Yersinia pestis Angola plasmid new_pCD, complete sequence NC_010157 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 162417751 Pathogen yopH protein-tyrosine-phosphatase YopH YpAngola_B0067 4 COG5599 PTP2, Protein tyrosine phosphatase Signal transduction mechanisms 162417814 Common tnpR resolvase TnpR YpAngola_B0090 147 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 162417787 Pathogen - hypothetical protein YpAngola_B0026 1 None None None 162417784 Pathogen yscE type III secretion appartus protein YscE YpAngola_B0056 1 None None None 162417756 Common - putative transposase, truncation YpAngola_B0068 43 None None None 162417801 Pathogen yscM type III secretion apparatus protein YscM YpAngola_B0064 2 None None None 162417792 Common yscU type III secretion appartus protein YscU YpAngola_B0048 129 COG4792 EscU, Type III secretory pathway, component EscU Intracellular trafficking and secretion 162417772 Common - integrase core domain protein YpAngola_B0001 98 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417768 Pathogen lcrG type III secretion protein LcrG YpAngola_B0033 5 None None None 162417789 Pathogen tap RepA leader peptide Tap YpAngola_B0079 1 None None None 162417753 Common - putative addiction module antidote protein, CC2985 family YpAngola_B0005 22 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 162417758 Pathogen - hypothetical protein YpAngola_B0087 1 None None None 162417736 Common - Integrase core domain protein YpAngola_B0097 84 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417816 Common - plasmid partition protein, ParB family YpAngola_B0008 22 COG1475 Spo0J, Predicted transcriptional regulators Transcription 162417770 Common yscQ type III secretion apparatus protein YscQ YpAngola_B0044 21 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 162417741 Common yscT type III secretion apparatus protein YscT YpAngola_B0047 22 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 162417790 Common - transposase YpAngola_B0093 64 None None None 162417761 Common yscR type III secretion apparatus protein YscR YpAngola_B0045 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 162417746 Common - hypothetical protein YpAngola_B0081 101 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417766 Pathogen yscY type III secretion chaperone YscY YpAngola_B0036 5 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 162417800 Pathogen - hypothetical protein YpAngola_B0007 1 None None None 162417807 Common - plasmid stabilization system protein, RelE/ParE family YpAngola_B0004 24 COG3668 ParE, Plasmid stabilization system protein General function prediction only 162417805 Pathogen - hypothetical protein YpAngola_B0022 1 None None None 162417810 Common repA plasmid replication protein RepA YpAngola_B0078 8 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 162417780 Common - Integrase core domain protein YpAngola_B0094 129 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417783 Common - transposase YpAngola_B0012 64 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417797 Pathogen yscX type III secretion protein YscX YpAngola_B0037 5 None None None 162417755 Common yscL type III secretion ATPase regulator YscL YpAngola_B0063 46 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 162417739 Common yscF type III secretion apparatus needle protein YscF YpAngola_B0057 6 None None None 162417764 Common lcrD type III secretion protein LcrD YpAngola_B0035 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 162417779 Common yopT cysteine protease YopT YpAngola_B0016 6 None None None 162417820 Pathogen - putative replication regulatory protein YpAngola_B0080 5 None None None 162417776 Pathogen - hypothetical protein YpAngola_B0091 1 None None None 162417743 Pathogen - hypothetical protein YpAngola_B0053 1 None None None 162417748 Pathogen yerA YopE regulator YerA YpAngola_B0002 3 None None None 162417785 Pathogen - hypothetical protein YpAngola_B0027 1 None None None 162417795 Pathogen yopK YopK protein YpAngola_B0015 1 None None None 162417812 Pathogen yopB translocator protein YopB YpAngola_B0030 5 COG5613 COG5613, Uncharacterized conserved protein Function unknown 162417804 Common - putative transposase, truncation YpAngola_B0084 21 None None None 162417774 Pathogen - hypothetical protein YpAngola_B0085 1 None None None 162417762 Pathogen - hypothetical protein YpAngola_B0071 1 None None None 162417733 Pathogen yscB YopN-specific chaperone YscB YpAngola_B0052 5 None None None 162417818 Common - putative transposase YpAngola_B0089 51 None None None 162417745 Common lcrS transposase YpAngola_B0065 54 None None None 162417737 Pathogen - hypothetical protein YpAngola_B0018 1 None None None 162417802 Common - putative transposase, truncation YpAngola_B0023 2 None None None 162417793 Pathogen tyeA type III secretion effector delivery regulator TyeA YpAngola_B0039 5 None None None 162417760 Common lcrH type III secretion low calcium response chaperone LcrH YpAngola_B0031 19 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 162417769 Common - transposase YpAngola_B0082 64 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417809 Common yscD type III secretion apparatus protein YscD YpAngola_B0055 8 None None None 162417808 Pathogen yscG type III secretion chaperone YscG YpAngola_B0058 5 None None None 162417813 Pathogen sycH YopH-specific chaperone SycH YpAngola_B0095 2 None None None 162417757 Common yscJ type III secretion apparatus lipoprotein YscJ YpAngola_B0061 42 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 162417778 Common yopN type III secretion regulator YopN YpAngola_B0040 7 None None None 162417771 Pathogen yscK type III secretion apparatus protein YscK YpAngola_B0062 5 None None None 162417735 Common - putative transposase, truncation YpAngola_B0024 54 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417740 Common - transposase YpAngola_B0088 54 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 162417767 Common - plasmid partition protein, ParA family YpAngola_B0009 198 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 162417806 Common lcrF thermoregulatory protein LcrF YpAngola_B0050 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 162417799 Pathogen - hypothetical protein YpAngola_B0010 1 None None None 162417773 Common - Integrase core domain protein YpAngola_B0069 123 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 162417759 Common yscC type III secretion outer membrane pore YscC YpAngola_B0054 139 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 162417750 Common yscN type III secretion apparatus H+-transporting two-sector ATPase YscN YpAngola_B0041 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 162417791 Pathogen - hypothetical protein YpAngola_B0076 1 None None None 162417786 Common - hypothetical protein YpAngola_B0006 5 None None None 162417815 Pathogen - hypothetical protein YpAngola_B0051 1 None None None 162417777 Common yopO protein kinase YopO YpAngola_B0072 5 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 162417765 Pathogen yscH type III secretion protein YopR YpAngola_B0059 4 None None None 162417738 Pathogen yscI type III secretion apparatus protein YscI YpAngola_B0060 5 None None None 162417747 Common yscS type III secretion apparatus protein YscS YpAngola_B0046 39 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 162417798 Pathogen yopJ effector protein YopJ YpAngola_B0070 7 None None None 162417742 Pathogen yopE outer membrane virulence protein YopE YpAngola_B0003 3 None None None 162417734 Pathogen yopD translocator protein YopD YpAngola_B0029 5 None None None 162417817 Pathogen yscO type III secretion protein YscO YpAngola_B0042 5 None None None 162417781 Pathogen - hypothetical protein YpAngola_B0092 1 None None None 162417752 Pathogen - hypothetical protein YpAngola_B0020 1 None None None 162417788 Common - putative insertion sequence ATP-binding protein YpAngola_B0096 89 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 162417796 Pathogen - hypothetical protein YpAngola_B0021 1 None None None 162417775 Pathogen virG type III secretion system chaperone VirG YpAngola_B0049 4 None None None 162417763 Pathogen sycT YopT-specific chaperone SycT YpAngola_B0017 3 None None None 162417749 Pathogen - hypothetical protein YpAngola_B0077 1 None None None 162417744 Pathogen lcrV virulence-associated V antigen LcrV YpAngola_B0032 5 None None None 162417754 Pathogen yscP type III secretion system needle length determinant YscP YpAngola_B0043 4 None None None 162417794 Pathogen - hypothetical protein YpAngola_B0075 2 None None None 162417782 Pathogen - putative type III secretion chaperone YpAngola_B0073 3 None None None 162417819 Common yopM effector protein YopM YpAngola_B0025 14 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 162417811 Pathogen sycN YopN-specific chaperone SycN YpAngola_B0038 5 None None None 162417803 Pathogen lcrR type III secretion system regulator LcrR YpAngola_B0034 5 None None None