Neisseria meningitidis 053442, complete genome NC_010120 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 161870434 Common hisG ATP phosphoribosyltransferase NMCC_1483 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 161870395 Pathogen - hypothetical protein NMCC_1442 1 None None None 161869861 Common sdhC succinate dehydrogenase cytochrome B subunit NMCC_0892 74 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 161869738 Common - transporter, NadC family NMCC_0758 137 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 161870718 Common tal transaldolase NMCC_1791 106 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 161869390 Common - hypothetical protein NMCC_0397 23 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 161871005 Common - hypothetical protein NMCC_2101 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 161870399 Common rpoD RNA polymerase primary sigma factor NMCC_1446 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 161870610 Common rpsT 30S ribosomal protein S20 NMCC_1679 206 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 161869045 Common - peptidyl-prolyl cis-trans isomerase NMCC_0028 154 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 161869076 Pathogen - hypothetical protein NMCC_0065 1 None None None 161870858 Common dapB dihydrodipicolinate reductase NMCC_1945 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 161870654 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase NMCC_1724 209 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 161869974 Pathogen - phage anti-repressor protein NMCC_1007 1 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 161869113 Pathogen - hypothetical protein NMCC_0104 2 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 161869496 Common apbE thiamine biosynthesis protein NMCC_0509 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 161870180 Common ndk nucleoside diphosphate kinase NMCC_1220 229 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 161870890 Common oxyR hydrogen peroxide-inducible genes activator NMCC_1979 153 COG0583 LysR, Transcriptional regulator Transcription 161870544 Common - integral membrane protein NMCC_1609 27 COG4648 COG4648, Predicted membrane protein Function unknown 161869389 Common - hypothetical protein NMCC_0396 21 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 161869551 Common ppsA phosphoenolpyruvate synthase NMCC_0566 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 161869850 Pathogen - lipoprotein NMCC_0881 1 None None None 161870141 Common - hypothetical protein NMCC_1180 30 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 161870958 Common - hypothetical protein NMCC_2053 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 161869757 Common norM putative transmembrane efflux protein NMCC_0777 177 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 161870403 Pathogen - hypothetical protein NMCC_1450 1 None None None 161870628 Common pheA chorismate mutase NMCC_1697 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 161869037 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosmine deacetylase NMCC_0020 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 161869231 Common cyaY cyaY protein NMCC_0235 43 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 161870619 Common - Tou1 NMCC_1688 32 COG3177 COG3177, Uncharacterized conserved protein Function unknown 161870379 Common dsbD thiol:disulfide interchange protein DsbD NMCC_1425 117 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 161869376 Common fhs formate--tetrahydrofolate ligase NMCC_0383 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 161869251 Common - hypothetical protein NMCC_0256 14 COG0824 FcbC, Predicted thioesterase General function prediction only 161869398 Pathogen - hypothetical protein NMCC_0405 1 None None None 161869472 Common lctP L-lactate permease, putative NMCC_0484 105 COG1620 LldP, L-lactate permease Energy production and conversion 161870563 Common mtrR TetR/AcrR family transcriptional regulator, acrAB operon repressor NMCC_1629 125 COG1309 AcrR, Transcriptional regulator Transcription 161869545 Common - oxidoreductase NMCC_0560 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 161869922 Common - hypothetical protein NMCC_0954 38 COG3926 zliS, Putative secretion activating protein General function prediction only 161869404 Common - ATP-cone domain protein NMCC_0412 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 161869054 Common - possible periplasmic protein NMCC_0037 44 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 161869084 Common - hypothetical protein NMCC_0073 5 None None None 161869576 Pathogen - MafB-related protein NMCC_0592 1 None None None 161870886 Common - sodium/alanine symporter, putative NMCC_1975 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 161869647 Pathogen - hypothetical protein NMCC_0664 1 None None None 161869772 Common - hypothetical protein NMCC_0795 117 COG2127 COG2127, Uncharacterized conserved protein Function unknown 161870960 Common lpcA phosphoheptose isomerase NMCC_2055 123 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 161870711 Common aroE shikimate dehydrogenase NMCC_1783 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 161870568 Common - cytochrome C555 NMCC_1634 15 COG3245 CycB, Cytochrome c5 Energy production and conversion 161869191 Common hrpA ATP-dependent RNA helicase HrpA NMCC_0194 86 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 161869561 Common hisF imidazoleglycerol phosphate synthase subunit NMCC_0576 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 161869167 Pathogen - hypothetical protein NMCC_0162 1 None None None 161870874 Pathogen - integral membrane protein NMCC_1962 1 None None None 161869316 Pathogen - periplasmic protein NMCC_0321 1 None None None 161870594 Pathogen - cell-surface protein NMCC_1661 1 None None None 161869695 Common xerD integrase/recombinase NMCC_0715 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 161870442 Common sohB serine protease SohB NMCC_1491 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 161869380 Common tyrS tyrosyl-tRNA synthetase NMCC_0387 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869863 Common sdhA succinate dehydrogenase flavoprotein subunit NMCC_0894 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 161870158 Pathogen - hypothetical protein NMCC_1197 3 None None None 161869146 Common - PTS system, IIAB component NMCC_0140 87 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 161870775 Common phr deoxyribodopyrimidine photolyase NMCC_1857 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 161870504 Pathogen - hypothetical protein NMCC_1567 1 None None None 161870124 Pathogen nlaIVR type II restriction enzyme NlaIV NMCC_1163 1 None None None 161869859 Common lpdA2 dihydrolipoamide dehydrogenase NMCC_0890 233 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 161869921 Pathogen - hypothetical protein NMCC_0953 1 None None None 161869531 Common tatC sec-independent protein translocase component NMCC_0545 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 161869238 Common - para-aminobenzoate synthase component I NMCC_0243 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 161869258 Common sspB stringent starvation protein B NMCC_0263 64 COG2969 SspB, Stringent starvation protein B General function prediction only 161869094 Common tex transcriptional accessory protein Tex, putative NMCC_0083 177 COG2183 Tex, Transcriptional accessory protein Transcription 161869069 Common pilT twitching motility protein PilT NMCC_0052 217 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 161869700 Common rfbD dTDP-4-dehydrorhamnose reductase NMCC_0720 170 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 161870790 Pathogen - hypothetical protein NMCC_1872 2 None None None 161870200 Common - cation transport ATPase, E1-E2 family NMCC_1240 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 161869904 Common - rubredoxin NMCC_0936 120 COG1773 COG1773, Rubredoxin Energy production and conversion 161870729 Common gloA lactoylglutathione lyase NMCC_1802 134 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 161869507 Common gcvT aminomethyltransferase NMCC_0520 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 161870837 Common - IS1655 transposase NMCC_1919 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161869024 Common - thioredoxin-related transmembrane protein NMCC_0006 87 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 161870382 Common slyD FKBP-type peptidyl-prolyl cis-trans isomerase SlyD NMCC_1428 126 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 161870111 Common - hypothetical protein NMCC_1150 11 None None None 161870947 Pathogen - hypothetical protein NMCC_2041 1 None None None 161869714 Common pilZ type IV pilus assembly protein PilZ NMCC_0734 32 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 161869198 Common - hypothetical inner membrane protein NMCC_0201 57 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 161869640 Common - hypothetical protein NMCC_0657 11 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 161870315 Common aroD 3-dehydroquinate dehydratase NMCC_1357 52 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 161871029 Common rplN 50S ribosomal protein L14 NMCC_1995a 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 161870551 Common - sodium- and chloride-dependent transporter NMCC_1617 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 161870274 Common - putative insertion element IS1106 transposase NMCC_1315 30 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870057 Common - putative ATP-binding protein NMCC_1093 25 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 161870902 Common rplF 50S ribosomal protein L6 NMCC_1992 235 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 161870402 Pathogen - hypothetical protein NMCC_1449 1 None None None 161869124 Common cytX probable hydroxymethylpyrimidine transporter CytX NMCC_0118 36 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 161870174 Common rpsA 30S ribosomal protein S1 NMCC_1214 222 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 161870340 Common clpB ATP-dependent Clp protease ATP-binding subunit ClpB NMCC_1384 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 161869681 Common - hypothetical protein NMCC_0699 104 COG1161 COG1161, Predicted GTPases General function prediction only 161869754 Common - tetR-family transcriptional regulator NMCC_0774 54 COG1309 AcrR, Transcriptional regulator Transcription 161869884 Pathogen - hypothetical protein NMCC_0915 1 None None None 161870288 Common - hypothetical protein NMCC_1329 17 None None None 161870039 Common cysD sulfate adenylyltransferase, subunit 2 NMCC_1072 126 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 161870603 Common - hypothetical protein NMCC_1671 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 161869938 Common glyA glycine hydroxymethyltransferase NMCC_0971 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 161870644 Common prpC citrate synthase NMCC_1714 194 COG0372 GltA, Citrate synthase Energy production and conversion 161869423 Common pbp3 Penicillin-binding protein 3 NMCC_0431 106 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 161869599 Common apaH bis(5'-nucleosyl)-tetraphosphatase NMCC_0615 91 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 161869580 Pathogen - hypothetical protein NMCC_0596 1 None None None 161869811 Common ilvA threonine dehydratase biosynthetic NMCC_0840 209 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 161869583 Common - hypothetical protein NMCC_0599 2 None None None 161871037 Common rpoA DNA-directed RNA polymerase alpha chain NMCC_1984 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 161869329 Common - hypothetical protein NMCC_0335 84 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 161869847 Pathogen - membrane protein NMCC_0878 1 None None None 161869282 Common - hypothetical protein NMCC_0287 5 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 161870794 Common - competence protein NMCC_1876 165 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 161870570 Common fixQ cb-type cytochrome c oxidase subunit IV NMCC_1636 2 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 161870209 Common - hypothetical protein NMCC_1249 131 COG1678 COG1678, Putative transcriptional regulator Transcription 161870424 Common - hypothetical protein NMCC_1472 90 COG0795 COG0795, Predicted permeases General function prediction only 161869621 Pathogen - lipoprotein NMCC_0638 1 None None None 161870875 Common - integral membrane protein NMCC_1964 19 COG1289 COG1289, Predicted membrane protein Function unknown 161870574 Common - hypothetical protein NMCC_1640 41 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 161869322 Common - hypothetical protein NMCC_0327 124 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 161870807 Common - hypothetical protein NMCC_1889 69 COG1479 COG1479, Uncharacterized conserved protein Function unknown 161870363 Common - hypothetical protein NMCC_1407 152 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 161870094 Pathogen - hypothetical protein NMCC_1132 1 None None None 161870323 Common - inner membrane protein NMCC_1367 23 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 161869106 Pathogen - hypothetical protein NMCC_0096 1 None None None 161870046 Common vacB ribonuclease NMCC_1082 196 COG0557 VacB, Exoribonuclease R Transcription 161869805 Common panC pantoate--beta-alanine ligase NMCC_0830 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 161869293 Common fabG 3-oxoacyl-[acyl-carrier protein] reductase NMCC_0298 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 161869464 Common - transmembrane transport protein NMCC_0476 57 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 161870443 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NMCC_1498 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 161869592 Common - hypothetical protein NMCC_0608 2 None None None 161869363 Common - hypothetical protein NMCC_0369 25 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 161869521 Common rplS 50S ribosomal protein L19 NMCC_0535 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 161869029 Common - transposase for IS1655 NMCC_0011 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161869898 Common - N-acetylmuramoyl-L-alanine amidase NMCC_0930 3 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 161869911 Common - tRNA-dihydrouridine synthase C NMCC_0943 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 161870007 Common - hypothetical protein NMCC_1040 4 None None None 161870240 Pathogen - membrane lipoprotein NMCC_1281 1 None None None 161869266 Common - D-methionine transport system substrate-binding protein NMCC_0271 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 161870018 Pathogen - hypothetical protein NMCC_1051 1 None None None 161870256 Common hscB molecular chaperone HscB (Hsc20) NMCC_1297 57 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 161869813 Common cysW sulphate permease inner membrane protein NMCC_0842 209 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 161869797 Common - hypothetical protein NMCC_0820 2 None None None 161870102 Common - hypothetical protein NMCC_1141 64 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 161869565 Common fbpC iron(III) ABC transporter, ATP-binding protein NMCC_0580 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 161870107 Common - lysR-family transcriptional regulator NMCC_1146 187 COG0583 LysR, Transcriptional regulator Transcription 161870491 Common - alanine or glycine:cation symporter, AGCS family NMCC_1547 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 161870216 Common lpdA dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) NMCC_1256 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 161869355 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein NMCC_0361 201 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 161869291 Common - IS1106A3 transposase NMCC_0296 42 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870844 Common fabF1 3-oxoacyl-[acyl-carrier-protein] synthase II NMCC_1926 211 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161869224 Pathogen - hypothetical protein NMCC_0228 3 None None None 161870266 Common zwf glucose 6-phosphate 1-dehydrogenase NMCC_1307 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 161870664 Common mraZ Protein mraZ NMCC_1734 132 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 161869827 Common - hypothetical protein NMCC_0856 77 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 161870580 Pathogen - hypothetical integral membrane protein NMCC_1646 1 None None None 161869724 Common hemE uroporphyrinogen decarboxylase NMCC_0744 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 161870727 Common ispZ intracellular septation protein A NMCC_1800 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 161869891 Common - membrane protein NMCC_0922 24 COG3686 COG3686, Predicted membrane protein Function unknown 161870589 Common - hypothetical protein NMCC_1656 5 None None None 161870247 Common - type III restriction/modification system modification methylase NMCC_1288 114 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 161870538 Common manB phosphoglucomutase/phosphomannomutase NMCC_1603 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 161870785 Common dsbA3 thiol:disulfide interchange protein DsbA NMCC_1867 41 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 161869209 Common - iron(III) ABC transporter, permease protein NMCC_0213 106 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 161870592 Pathogen - hypothetical protein NMCC_1659 1 None None None 161870930 Common tufA2 elongation factor TU NMCC_2021 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 161869098 Common rfbA2 glucose-1-phosphate thymidylyltransferase NMCC_0088 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 161869412 Common pilM type IV pilus assembly protein PilM NMCC_0420 62 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 161869176 Common - ABC transporter, permease protein NMCC_0173 190 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 161870366 Common pncB nicotinate phosphoribosyltransferase NMCC_1410 93 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 161870676 Common nadC nicotinate-nucleotide pyrophosphorylase NMCC_1748 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 161870792 Common - hypothetical protein NMCC_1874 37 None None None 161869470 Pathogen - hypothetical protein NMCC_0482 2 None None None 161870689 Common - transcriptional regulator, Fnr family NMCC_1761 154 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 161869100 Common lipA capsule polysaccharide modification protein NMCC_0090 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 161870034 Common - hypothetical protein NMCC_1067 28 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 161870767 Pathogen - hypothetical protein NMCC_1842 1 None None None 161869087 Common siaC polysialic acid capsule biosynthesis protein SiaC NMCC_0076 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 161871027 Common rplO 50S ribosomal protein L15 NMCC_1988a 197 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 161870050 Common glnD [protein-PII] uridylyltransferase NMCC_1086 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 161870680 Common pgmB beta-phosphoglucomutase NMCC_1752 130 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 161870813 Common nuoJ NADH dehydrogenase I chain J NMCC_1895 54 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 161869857 Pathogen - hypothetical protein NMCC_0888 1 None None None 161870168 Common plsC 1-acyl-SN-glycerol-3-phosphate acyltransferase NMCC_1207 117 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 161869653 Common - hypothetical protein NMCC_0670 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 161870189 Pathogen - hypothetical protein NMCC_1229 1 None None None 161869956 Common - hypothetical protein NMCC_0989 88 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 161869969 Pathogen - hypothetical protein NMCC_1002 1 None None None 161869990 Pathogen - hypothetical protein NMCC_1023 1 None None None 161871033 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NMCC_1418 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 161870227 Common - hypothetical membrane protein NMCC_1268 20 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 161870069 Common - ABC transporter, ATP-binding protein NMCC_1107 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 161870754 Common - hypothetical protein NMCC_1828 90 COG1738 COG1738, Uncharacterized conserved protein Function unknown 161869061 Common - competence/damage-inducible protein CinA C-terminal domain NMCC_0044 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 161870962 Pathogen - periplasmic protein NMCC_2057 1 None None None 161870026 Common - hypothetical protein NMCC_1059 182 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 161870948 Pathogen - integral membrane protein NMCC_2042 1 None None None 161869563 Common hisH imidazole-glycerol phosphate synthase amidotransferase component NMCC_0578 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 161869420 Common metK S-adenosylmethionine synthetase NMCC_0428 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 161870529 Common - hypothetical protein NMCC_1594 5 None None None 161869349 Common - bifunctional enzyme involved in thiolation and methylation of tRNA NMCC_0355 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 161869988 Common - hypothetical protein NMCC_1021 18 COG3422 COG3422, Uncharacterized conserved protein Function unknown 161870723 Common - hypothetical protein NMCC_1796 28 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 161869604 Common - hypothetical protein NMCC_0620 13 None None None 161870166 Pathogen - hypothetical protein NMCC_1205 1 None None None 161871015 Common - hypothetical protein NMCC_2111 3 None None None 161869612 Common - hypothetical protein NMCC_0628 91 COG2835 COG2835, Uncharacterized conserved protein Function unknown 161869770 Common - DNA-binding protein NMCC_0791 59 COG3943 COG3943, Virulence protein General function prediction only 161869189 Common - hypothetical protein NMCC_0192 3 None None None 161870300 Common aroA 5-enolpyruvoylshikimate-3-phosphate synthase NMCC_1342 227 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 161870063 Common - transporter, putative NMCC_1099 127 COG0628 PerM, Predicted permease General function prediction only 161870025 Common accA acetyl-CoA carboxylase, carboxyl transferase alpha subunit NMCC_1058 197 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 161870652 Common murG UDP-N-acetylglucosamine--N-acetylmuramyl- (pentape pyrophosphoryl-undecaprenol N-acetylglucosamine transferase NMCC_1722 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 161869158 Pathogen - hypothetical protein NMCC_0153 1 None None None 161869331 Common - hypothetical protein NMCC_0337 136 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 161870913 Common rplW 50S ribosomal protein L23 NMCC_2003 93 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 161870736 Common pgi2 glucose-6-phosphate isomerase 2 NMCC_1809 200 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 161869441 Pathogen - hypothetical protein NMCC_0452 1 None None None 161869135 Common rplM 50S ribosomal protein L13 NMCC_0129 218 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 161869836 Pathogen - hypothetical protein NMCC_0867 1 None None None 161870638 Common - hypothetical protein NMCC_1708 5 None None None 161870096 Pathogen - hypothetical protein NMCC_1134 1 None None None 161870839 Pathogen - hypothetical protein NMCC_1921 1 None None None 161870407 Pathogen - hypothetical protein NMCC_1454 1 None None None 161870190 Pathogen - hypothetical protein NMCC_1230 1 None None None 161870388 Pathogen - hypothetical protein NMCC_1434 1 None None None 161869736 Common pgm phosphoglucomutase NMCC_0756 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 161869483 Common - IS1106 transposase NMCC_0496 36 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870091 Common - molybdopterin-guanine dinucleotide biosynthesis protein A NMCC_1129 50 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 161870832 Common - hypothetical protein NMCC_1914 100 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 161870671 Common putP sodium/proline symporter NMCC_1743 167 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 161869059 Common - thiamin-binding periplasmic protein NMCC_0042 75 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 161869080 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase NMCC_0069 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 161870156 Common panD aspartate 1-decarboxylase NMCC_1195 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 161870920 Common rpsG 30S ribosomal protein S7 NMCC_2010 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 161870919 Common fusA elongation factor G NMCC_2009 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 161869246 Common - putative ABC transport system substrate-binding protein NMCC_0251 98 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 161870332 Common - IS1106A3 transposase NMCC_1376 4 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869699 Pathogen - hypothetical protein NMCC_0719 1 None None None 161870084 Common cca tRNA nucleotidyltransferase NMCC_1122 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 161869672 Pathogen - membrane protein NMCC_0690 2 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 161869435 Common - hypothetical protein NMCC_0443 20 COG2850 COG2850, Uncharacterized conserved protein Function unknown 161869878 Common trpG anthranilate synthase component II NMCC_0909 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 161869022 Common - periplasmic protein NMCC_0004 58 COG1434 COG1434, Uncharacterized conserved protein Function unknown 161869749 Common - NAD(P)H-flavin oxidoreductase NMCC_0769 92 COG0778 NfnB, Nitroreductase Energy production and conversion 161869589 Common - hypothetical protein NMCC_0605 3 None None None 161870236 Common trxA thioredoxin I NMCC_1277 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 161870941 Common - hypothetical protein NMCC_2035 19 None None None 161870698 Common - hypothetical protein NMCC_1770 3 None None None 161870778 Common - inner membrane trans-acylase protein NMCC_1860 93 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 161869052 Common - integral membrane protein NMCC_0035 94 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 161870707 Pathogen - FrpC operon protein NMCC_1779 1 None None None 161869947 Common - ADP-ribose pyrophosphatase NMCC_0980 163 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 161870773 Common - hypothetical protein NMCC_1855 25 COG2259 COG2259, Predicted membrane protein Function unknown 161870001 Pathogen - tail fibre protein, putative NMCC_1034 3 None None None 161870691 Pathogen - hypothetical protein NMCC_1763 1 None None None 161870037 Common cysJ sulphite reductase alpha subunit NMCC_1070 105 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 161870895 Common rpsD 30S ribosomal protein S4 NMCC_1985 216 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 161869636 Pathogen folI transcriptional regulator NMCC_0653 1 None None None 161870877 Common uppS undecaprenyl diphosphate synthase NMCC_1966 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 161869585 Pathogen mafA2 adhesin MafA2 NMCC_0601 1 None None None 161870080 Common recR recombination protein NMCC_1118 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 161870148 Common fadD1 long-chain-fatty-acid--CoA ligase NMCC_1187 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161870863 Pathogen - hypothetical protein NMCC_1951 1 None None None 161870210 Common - Putative Holliday junction resolvase NMCC_1250 181 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 161870074 Common lon ATP-dependent protease NMCC_1112 208 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 161869208 Common - hypothetical protein NMCC_0212 17 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 161869574 Common ppa inorganic pyrophosphatase NMCC_0589 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 161870865 Pathogen - hypothetical protein NMCC_1953 1 None None None 161870413 Common gshB glutathione synthetase NMCC_1461 131 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 161869447 Common - hypothetical protein NMCC_0458 4 None None None 161869774 Common pmbA pmbA protein NMCC_0797 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 161869498 Common nqrE Na(+)-translocating NADH-ubiquinone reductase subunit E NMCC_0511 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 161869139 Common petA ubiquinol-cytochrome c reductase iron-sulfur subunit NMCC_0133 92 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 161869628 Pathogen - hypothetical protein NMCC_0645 1 None None None 161869782 Common - glycosyl transferase NMCC_0805 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 161869165 Common - hypothetical protein NMCC_0160 3 COG2336 MazE, Growth regulator Signal transduction mechanisms 161869115 Pathogen - integral membrane protein NMCC_0106 1 COG1714 COG1714, Predicted membrane protein/domain Function unknown 161870182 Common - ftype IV pilus assembly protein NMCC_1222 72 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 161871008 Pathogen - hypothetical protein NMCC_2104 2 None None None 161869665 Common rplT 50S ribosomal protein L20 NMCC_0683 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 161870436 Common hisD histidinol dehydrogenase NMCC_1485 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 161870809 Common nuoL NADH dehydrogenase I chain L NMCC_1891 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 161869793 Pathogen - hypothetical protein NMCC_0816 1 None None None 161870221 Common - SUN-family protein NMCC_1262 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 161870617 Common - hypothetical protein NMCC_1686 203 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 161870712 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase NMCC_1784 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 161869747 Common - cystathionine gamma-synthase NMCC_0767 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 161869976 Pathogen - hypothetical protein NMCC_1009 1 None None None 161869147 Common ptsH sugar transport PTS system phosphocarrier protein HPR NMCC_0141 148 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 161870137 Common - cation uptake regulator NMCC_1176 72 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 161870634 Common - opacity protein NMCC_1704 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 161869374 Common - sugar-phosphate nucleotidyl transferase NMCC_0381 217 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 161869132 Common gpsA glycerol-3-phosphate dehydrogenase NMCC_0126 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 161869693 Common - D-alanyl-D-alanine-endopeptidase NMCC_0713 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 161869763 Common htpX membrane-bound zinc metallopeptidase NMCC_0783 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 161870405 Common lbpA lactoferrin binding protein A NMCC_1452 61 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 161871021 Common - hypothetical protein NMCC_2117 92 COG1720 COG1720, Uncharacterized conserved protein Function unknown 161870596 Common - hypothetical protein NMCC_1664 2 None None None 161869269 Pathogen - hypothetical protein NMCC_0274 2 None None None 161870282 Pathogen - hypothetical DNA-binding protein NMCC_1323 1 None None None 161870851 Common sdaA L-serine dehydratase NMCC_1934 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 161869657 Pathogen - hypothetical protein NMCC_0674 1 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 161869963 Common - ABC transporter, ATP-binding protein NMCC_0996 203 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 161869882 Common - hypothetical protein NMCC_0913 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 161870412 Common dgk diacylglycerol kinase NMCC_1460 69 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 161869353 Common prmA ribosomal protein L11 methyltransferase NMCC_0359 183 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 161870983 Common - hypothetical protein NMCC_2078 4 None None None 161869655 Common lnt apolipoprotein N-acyltransferase NMCC_0672 153 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 161869249 Common - VacJ-related protein NMCC_0254 93 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 161869152 Common thiC thiamin biosynthesis protein NMCC_0147 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 161870642 Common prpF putative AcnD-accessory protein PrpF NMCC_1712 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 161869392 Common - hypothetical protein NMCC_0399 51 COG2501 COG2501, Uncharacterized conserved protein Function unknown 161869126 Pathogen - integral membrane protein NMCC_0120 1 None None None 161869868 Common sucB dihydrolipoamide succinyltransferase E2 component NMCC_0899 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 161870299 Common greA transcription elongation factor NMCC_1341 197 COG0782 GreA, Transcription elongation factor Transcription 161870397 Common secA preprotein translocase SecA subunit NMCC_1444 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 161869156 Pathogen tspB TspB protein NMCC_0151 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 161869500 Common nqrC Na(+)-translocating NADH-ubiquinone reductase subunit C NMCC_0513 47 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 161870884 Common fabZ (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase NMCC_1973 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 161869278 Common atpG ATP synthase gamma chain NMCC_0283 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 161870020 Common - hypothetical protein NMCC_1053 10 COG3779 COG3779, Uncharacterized protein conserved in bacteria Function unknown 161869459 Common - periplasmic serine protease NMCC_0471 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 161870207 Pathogen - hypothetical protein NMCC_1247 1 None None None 161870720 Common glu glutamyl-tRNA synthetase NMCC_1793 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 161870327 Common fumC fumarate hydratase class II NMCC_1371 210 COG0114 FumC, Fumarase Energy production and conversion 161870997 Common - periplasmic protein NMCC_2092 92 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 161870751 Common farB fatty acid efflux system protein NMCC_1825 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 161870700 Common - hypothetical protein NMCC_1772 2 None None None 161869215 Pathogen - hypothetical protein NMCC_0219 1 None None None 161870469 Common thiD phosphomethylpyrimidine kinase NMCC_1525 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 161869840 Common - lipoprotein NMCC_0871 26 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 161870092 Common - two-component system, NarL family, nitrate/nitrite sensor histidine kinase NMCC_1130 139 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 161869645 Common comL competence lipoprotein NMCC_0662 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 161870495 Common alr alanine racemase NMCC_1552 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 161869638 Common - amino acid permease ATP-binding protein NMCC_0655 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 161869196 Common argJ arginine biosynthesis bifunctional protein NMCC_0199 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 161870426 Common - hypothetical protein NMCC_1474 119 COG0795 COG0795, Predicted permeases General function prediction only 161870572 Common fixN cb-type cytochrome c oxidase subunit I NMCC_1638 141 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 161870393 Common - hypothetical protein NMCC_1440 17 None None None 161869108 Common pykA pyruvate kinase NMCC_0098 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 161870506 Common spoT guanosine-3',5'-bis(diphosphate) 3'-pyrophophohydrolase NMCC_1569 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 161870576 Common exbB biopolymer transport protein NMCC_1642 151 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 161869324 Common - DNA-binding protein NMCC_0329 34 COG2944 COG2944, Predicted transcriptional regulator Transcription 161870325 Pathogen - hypothetical protein NMCC_1369 1 None None None 161869538 Common - hypothetical protein NMCC_0552 164 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 161869849 Common efp elongation factor P NMCC_0880 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 161869918 Common - hypothetical protein NMCC_0950 7 COG1414 IclR, Transcriptional regulator Transcription 161869092 Common ctrC capsule polysaccharide export inner-membrane protein NMCC_0081 63 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 161869387 Common - hypothetical protein NMCC_0394 19 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 161870805 Common nuoN NADH dehydrogenase chain N NMCC_1887 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 161870900 Common rpsE 30S ribosomal protein S5 NMCC_1990 238 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 161869314 Common - transposase for IS1016 NMCC_0319 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870462 Pathogen - hypothetical protein NMCC_1517 1 None None None 161870489 Common - integral membrane protein NMCC_1545 9 None None None 161870310 Pathogen - hypothetical protein NMCC_1352 1 None None None 161869268 Common ubiX 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NMCC_0273 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 161871011 Common - IS1016 transposase NMCC_2107 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870732 Pathogen - hypothetical protein NMCC_1805 1 None None None 161870272 Pathogen - hypothetical protein NMCC_1313 1 None None None 161869718 Common upp uracil phosphoribosyltransferase NMCC_0738 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 161869298 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase III NMCC_0303 226 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 161869688 Pathogen - hypothetical protein NMCC_0708 1 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 161870482 Common - YhbX/YhjW/YijP/YjdB family protein NMCC_1538 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 161869759 Common purA adenylosuccinate synthetase NMCC_0779 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 161870514 Common - hypothetical protein NMCC_1577 35 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 161869716 Common grlA monothiol glutaredoxin NMCC_0736 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 161870417 Common - transcriptional regulator, GntR family NMCC_1465 96 COG1802 GntR, Transcriptional regulators Transcription 161870458 Common - hypothetical protein NMCC_1513 50 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 161869937 Common - IS1106 transposase NMCC_0969 30 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870848 Common prlC oligopeptidase A NMCC_1931 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 161870361 Common lysC aspartate kinase NMCC_1405 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 161870965 Common - adhesin component NMCC_2060 3 None None None 161869019 Common - acetyltransferase NMCC_0001 21 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 161870373 Common - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NMCC_1417 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 161870475 Common nor nitric oxide reductase NMCC_1531 72 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 161870970 Common rpsB 30S ribosomal protein S2 NMCC_2065 218 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 161869547 Common amtB ammonium transporter NMCC_0562 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 161869401 Common - hypothetical protein NMCC_0409 5 None None None 161869606 Common - periplasmic protein NMCC_0622 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 161870542 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NMCC_1607 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 161869732 Common - putative iron-dependent peroxidase NMCC_0752 50 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 161870783 Common ostA organic solvent tolerance protein, putative NMCC_1865 116 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 161869178 Common - probable nicotinate-nucleotide adenylyltransferase NMCC_0175 188 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 161869128 Common - integral membrane protein NMCC_0122 29 COG2056 COG2056, Predicted permease General function prediction only 161871026 Common infA translation initiation factor IF-1 NMCC_1987b 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 161869536 Common - zinc-binding alcohol dehydrogenase NMCC_0550 171 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 161869555 Common lolA periplasmic carrier protein NMCC_0570 74 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 161869838 Pathogen - hypothetical protein NMCC_0869 1 None None None 161870139 Common - Glycerate kinase NMCC_1178 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 161870932 Common - DNA methylase NMCC_2026 208 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 161869173 Common thrB homoserine kinase NMCC_0170 66 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 161870129 Common - dnaJ-family protein NMCC_1168 233 COG3671 COG3671, Predicted membrane protein Function unknown 161870122 Common leuD 3-isopropylmalate dehydratase small subunit NMCC_1161 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 161869048 Common metG methionyl-tRNA synthetase NMCC_0031 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869842 Common - xanthine/uracil permease family protein NMCC_0873 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 161870636 Common - prephenate dehydrogenase, putative NMCC_1706 154 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 161869414 Common engB GTP-binding protein NMCC_0422 184 COG0218 COG0218, Predicted GTPase General function prediction only 161870253 Pathogen - hypothetical protein NMCC_1294 1 None None None 161870521 Common - lipase NMCC_1585 108 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 161869469 Common aspC aspartate aminotransferase NMCC_0481 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 161870032 Common mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase NMCC_1065 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 161870330 Common - drug resistance translocase family protein NMCC_1374 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 161869027 Common - BolA/YrbA family protein NMCC_0009 61 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 161870818 Common nuoF NADH dehydrogenase I chain F NMCC_1900 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 161869876 Common - phosphatidylserine decarboxylase precursor-related protein NMCC_0907 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 161870023 Common - hypothetical protein NMCC_1056 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 161870682 Common galM aldose 1-epimerase (mutarotase) NMCC_1754 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 161870130 Common - hypothetical protein NMCC_1169 124 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 161870565 Common mtrF efflux pump component MtrF NMCC_1631 40 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 161869171 Common - amino-acid transport protein NMCC_0168 36 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 161869365 Pathogen - hypothetical protein NMCC_0371 1 None None None 161869462 Pathogen - hypothetical protein NMCC_0474 1 None None None 161871035 Common speB agmatinase NMCC_1673 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 161869020 Pathogen - putative periplasmic protein NMCC_0002 1 None None None 161870800 Common - ABC transporter, ATP-binding protein NMCC_1882 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 161869801 Common - YabO/YceC/SfhB family protein NMCC_0824 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 161869505 Common - hypothetical protein NMCC_0518 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 161870437 Common hisC histidinol-phosphate aminotransferase NMCC_1486 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 161869896 Common - transposase NMCC_0927 51 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870957 Common - IS1016 transposase NMCC_2051 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870666 Common bacA bacitracin resistance protein NMCC_1738 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 161869075 Common - DNA transport competence protein NMCC_0064 126 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 161870349 Common - acyl-CoA hydrolase NMCC_1393 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 161869034 Common gnd 6-phosphogluconate dehydrogenase, decarboxylating NMCC_0017 144 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 161870245 Common truB tRNA pseudouridine synthase B NMCC_1286 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 161869248 Pathogen - hypothetical protein NMCC_0253 1 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 161869067 Common - integral membrane protein NMCC_0050 55 COG1289 COG1289, Predicted membrane protein Function unknown 161869803 Common - spermidine synthase NMCC_0826 59 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 161869515 Common - IS1016 transposase NMCC_0529 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870016 Common - phytoene synthase, putative NMCC_1049 113 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 161870176 Common - transcriptional regulator, MerR family NMCC_1216 78 COG0789 SoxR, Predicted transcriptional regulators Transcription 161870661 Common penA penicillin-binding protein 2 NMCC_1731 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 161869799 Pathogen - hypothetical protein NMCC_0822 1 None None None 161870059 Common - lipoic acid synthetase NMCC_1095 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 161870104 Common - putative ATPase NMCC_1143 235 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 161870220 Common - hypothetical protein NMCC_1261 5 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 161869610 Common lpxK tetraacyldisaccharide kinase NMCC_0626 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 161870263 Common - RpiR/YebK/YfhH family transcriptional regulator NMCC_1304 131 COG1737 RpiR, Transcriptional regulators Transcription 161869697 Common - thioredoxin NMCC_0717 19 None None None 161869590 Common - hypothetical protein NMCC_0606 13 None None None 161869319 Common drg type II restriction endonuclease NMCC_0324 5 None None None 161870626 Common pdxJ pyridoxal phophate biosynthetic protein NMCC_1695 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 161870009 Common chpA2 PEMK-like protein NMCC_1042 53 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 161870929 Common secE preprotein translocase SECE subunit NMCC_2019 23 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 161869790 Common - bacteriocin resistance protein, putative NMCC_0813 41 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 161870846 Common katA catalase NMCC_1929 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 161869361 Common carB carbamoyl phosphate synthase large subunit NMCC_0367 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 161869871 Common sucC succinyl-CoA synthetase beta subunit NMCC_0902 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 161869096 Common galE2 UDP-glucose 4-epimerase NMCC_0086 196 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 161870197 Common priB primosomal replication protein NMCC_1237 9 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 161869752 Pathogen - hypothetical protein NMCC_0772 1 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 161869035 Pathogen - hypothetical protein NMCC_0018 1 None None None 161870478 Common - pilS cassette NMCC_1534 4 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161870747 Pathogen - hypothetical protein NMCC_1821 1 None None None 161869982 Common - N-acetylmuramoyl-L-alanine amidase NMCC_1015 2 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 161870738 Common pilD leader peptidase (prepilin peptidase) / N-methyltransferase NMCC_1811 143 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 161869133 Common - hypothetical protein NMCC_0127 2 None None None 161870409 Common fadD2 long-chain-fatty-acid--CoA-ligase NMCC_1457 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161869928 Pathogen - hypothetical protein NMCC_0960 1 None None None 161869307 Common - hypothetical protein NMCC_0312 201 COG0313 COG0313, Predicted methyltransferases General function prediction only 161869999 Common - hypothetical protein NMCC_1032 26 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 161869818 Common dnaB replicative DNA helicase NMCC_0847 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 161870975 Pathogen - hypothetical protein NMCC_2070 1 None None None 161870765 Pathogen - hypothetical protein NMCC_1839 1 None None None 161870045 Common typA GTP-binding protein NMCC_1078 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 161870295 Common - aminopeptidase NMCC_1337 202 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 161869670 Common himA integration host factor alpha-subunit NMCC_0688 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 161870113 Pathogen - hypothetical protein NMCC_1152 1 None None None 161869338 Common - prolyl endopeptidase NMCC_0344 110 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 161870752 Common farA fatty acid efflux system protein NMCC_1826 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 161870289 Common - IS1106A3 transposase NMCC_1330 40 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869707 Common cysK cysteine synthase NMCC_0727 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 161870825 Common - putative integral membrane protein NMCC_1907 17 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 161870926 Common rplA 50S ribosomal protein L1 NMCC_2016 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 161870161 Common - iron-sulphur binding protein NMCC_1200 35 COG0633 Fdx, Ferredoxin Energy production and conversion 161870650 Common ddlB D-alanine--D-alanine ligase B NMCC_1720 216 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 161870524 Pathogen - hypothetical protein NMCC_1588 1 None None None 161869347 Common xerC integrase/recombinase NMCC_0353 229 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 161870501 Common - adenine specific methylase, putative NMCC_1558 220 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 161869384 Common lytB 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NMCC_0391 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 161870999 Common - peptide transporter NMCC_2095 77 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 161870968 Common - hypothetical protein NMCC_2063 152 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 161869949 Pathogen - hypothetical protein NMCC_0982 1 None None None 161870990 Common - protease IV NMCC_2085 159 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 161870740 Common - Hypothetical zinc-binding protein NMCC_1813 60 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 161869567 Common fbpA iron(III) ABC transporter, periplasmic binding protein NMCC_0582 114 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 161869734 Common - amino acid permease integral membrane protein NMCC_0754 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 161870830 Common uvrD DNA helicase II NMCC_1912 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 161869187 Pathogen - hypothetical protein NMCC_0190 1 None None None 161869449 Pathogen - periplasmic protein NMCC_0460 1 None None None 161870811 Common - cell filamentation protein Fic-related protein NMCC_1893 30 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 161870943 Common - histone macro-H2A1-related protein NMCC_2037 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 161869761 Pathogen - hypothetical protein NMCC_0781 1 None None None 161870582 Common relA GTP pyrophosphokinase NMCC_1648 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 161870302 Common - phopholipase D-family protein NMCC_1344 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 161870935 Pathogen - hypothetical protein NMCC_2029 1 None None None 161869618 Common accD acetyl-CoA carboxylase transferase beta subunit NMCC_0635 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 161869286 Pathogen - lacto-N-neotetraose biosynthesis glycosyl transferase-related protein NMCC_0291 1 None None None 161869940 Common ggt gamma-glutamyltranspeptidase NMCC_0973 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 161869568 Pathogen - hypothetical protein NMCC_0583 1 None None None 161870532 Common serS seryl-tRNA synthetase NMCC_1597 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869667 Common - hypothetical protein NMCC_0685 23 COG1106 COG1106, Predicted ATPases General function prediction only 161869426 Common - two-component system sensor kinase, OmpR family NMCC_0434 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 161870170 Common - hypothetical protein NMCC_1209 34 None None None 161869626 Common - hypothetical protein NMCC_0643 7 COG4859 COG4859, Uncharacterized protein conserved in bacteria Function unknown 161870841 Pathogen - hypothetical protein NMCC_1923 1 None None None 161870284 Common ruvC crossover junction endodeoxyribonuclease NMCC_1325 189 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 161869218 Common - putative inner membrane protein NMCC_0222 3 COG5346 COG5346, Predicted membrane protein Function unknown 161870370 Common - amino acid ABC transporter, permease protein NMCC_1414 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 161870344 Common gluD glutamate dehydrogenase, NAD-specific NMCC_1388 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 161870386 Common smpB small protein B NMCC_1432 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 161870937 Common - Smg protein NMCC_2031 28 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 161869475 Pathogen - transposase NMCC_0487 1 None None None 161869379 Common wbpC lipopolysaccharide biosynthesis protein WbpC, putative NMCC_0386 111 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 161869254 Common rpmE 50S ribosomal protein L31 NMCC_0259 203 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 161869479 Common ybjZ macrolide transport system ATP-binding protein NMCC_0491 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 161869965 Common - bacteriophage transposase NMCC_0998 21 None None None 161869750 Common - RNA-binding protein NMCC_0770 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 161870454 Common gpm phosphoglycerate mutase NMCC_1509 134 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 161869916 Common - phage integrase NMCC_0948 10 None None None 161870278 Pathogen - FrpC operon protein NMCC_1319 1 None None None 161869984 Pathogen - hypothetical protein NMCC_1017 1 None None None 161870534 Common prfA peptide chain release factor I NMCC_1599 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 161870419 Common - hypothetical protein NMCC_1467 88 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 161870329 Common ssb single-stranded binding protein NMCC_1373 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 161869154 Common - hypothetical protein NMCC_0149 8 COG4128 Zot, Zonula occludens toxin General function prediction only 161870909 Common rpsC 30S ribosomal protein S3 NMCC_1999 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 161870177 Common adhC alcohol dehydrogenase class-III NMCC_1217 197 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 161869719 Common - hypothetical protein NMCC_0739 15 COG4390 COG4390, Uncharacterized protein conserved in bacteria Function unknown 161869843 Common rlmB 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB NMCC_0874 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 161870992 Common argG argininosuccinate synthase NMCC_2087 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 161870013 Common - periplasmic protein NMCC_1046 29 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 161869686 Common - hypothetical protein NMCC_0706 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 161870586 Pathogen - hypothetical protein NMCC_1653 1 None None None 161870605 Common speA biosynthetic arginine decarboxylase NMCC_1674 103 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 161870799 Pathogen - hypothetical protein NMCC_1881 1 None None None 161870195 Common rplI 50S ribosomal protein L9 NMCC_1235 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 161870516 Common hemO haem utilisation protein NMCC_1580 12 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 161869276 Common atpH ATP synthase delta chain NMCC_0281 190 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 161869768 Common nmgI type II restriction endonuclease NMCC_0788 25 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 161869439 Pathogen - hypothetical protein NMCC_0450 1 None None None 161871025 Pathogen rpmJ 50S ribosomal protein L36 NMCC_1987a 1 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 161870893 Common minC septum site-determining protein NMCC_1982 92 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 161870694 Pathogen mafA2 adhesin MafA2 NMCC_1766 1 None None None 161870511 Pathogen - hypothetical protein NMCC_1574 1 None None None 161869908 Common dld D-lactate dehydrogenase NMCC_0940 32 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 161870205 Common - carboxy-terminal processing protease NMCC_1245 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 161870043 Common - nickel-dependent hydrogenase, b-type cytochrome subunit NMCC_1076 33 COG3658 COG3658, Cytochrome b Energy production and conversion 161869262 Common - soluble lytic murein transglycosylase, putative NMCC_0267 148 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 161869503 Common - membrane protein NMCC_0516 29 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 161869234 Common - insertion element IS1016 transposase NMCC_0239 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869689 Common folK 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine- pyrophosphokinase NMCC_0709 194 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 161869326 Pathogen - hypothetical protein NMCC_0331 1 None None None 161870976 Pathogen - hypothetical protein NMCC_2071 1 None None None 161869643 Common comA competence protein NMCC_0660 154 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 161870367 Common argS arginyl-tRNA synthetase NMCC_1411 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869194 Common hrpA' ATP-dependent DNA helicase NMCC_0197 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 161870065 Pathogen - membrane protein NMCC_1102 1 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 161869118 Common birA probable biotin-[acetyl-CoA-carboxylase] ligase NMCC_0112 216 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 161870509 Common apt adenine phosphoribosyltransferase NMCC_1572 184 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 161870262 Common pgi1 glucose-6-phosphate isomerase NMCC_1303 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 161870590 Pathogen - hypothetical protein NMCC_1657 1 None None None 161869780 Pathogen - periplasmic protein NMCC_0803 1 None None None 161869340 Pathogen - hypothetical protein NMCC_0346 1 None None None 161869159 Pathogen - hypothetical protein NMCC_0154 1 None None None 161869074 Pathogen - hypothetical protein NMCC_0057 1 None None None 161870439 Common - 3-hydroxyacid dehydrogenase NMCC_1488 171 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 161869978 Pathogen - hypothetical protein NMCC_1011 1 None None None 161869335 Pathogen - hypothetical protein NMCC_0341 1 None None None 161870356 Pathogen - lipoprotein NMCC_1400 2 COG3895 COG3895, Predicted periplasmic protein General function prediction only 161869090 Common ctrA capsule polysaccharide export outer membrane protein NMCC_0079 64 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 161870184 Common clpP ATP-dependent Clp protease, proteolytic subunit NMCC_1224 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 161869312 Common dnaA chromosomal replication initiator protein NMCC_0317 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 161870213 Pathogen - hypothetical protein NMCC_1253 1 None None None 161869373 Common - 4-hydroxyphenylacetate 3-hydroxylase, small subunit, putative NMCC_0380 98 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 161870010 Pathogen - hypothetical protein NMCC_1043 1 None None None 161871009 Pathogen - lipoprotein NMCC_2105 2 None None None 161870713 Common - ABC transporter, ATP-binding protein NMCC_1786 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 161871036 Common lpxB lipid-A-disaccharide synthase NMCC_1949 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 161870446 Common mtrA AraC-family transcriptional regulator NMCC_1501 124 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 161869487 Common dnaK chaperone protein (Heat shock protein 70) NMCC_0500 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 161869692 Common hfq Host factor-I protein NMCC_0712 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 161870269 Common - alcohol dehydrogenase, zinc-containing NMCC_1310 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 161869933 Common trpE anthranilate synthase component I NMCC_0965 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 161870954 Pathogen - integral membrane protein NMCC_2048 1 None None None 161870430 Common - hypothetical protein NMCC_1478 58 COG1359 COG1359, Uncharacterized conserved protein Function unknown 161870867 Common pdxA pyridoxal phosphate biosynthetic protein NMCC_1955 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 161869394 Common - hypothetical protein NMCC_0401 122 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 161869385 Common - phosphoglycolate phosphatase, putative NMCC_0392 70 COG0546 Gph, Predicted phosphatases General function prediction only 161869973 Pathogen - hypothetical protein NMCC_1006 1 None None None 161869855 Common metF 5,10-methylenetetrahydrofolate reductase NMCC_0886 145 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 161869150 Common - ABC-transport system ATP-binding protein NMCC_0144 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 161870556 Common - Histone acetyltransferase HPA2 NMCC_1622 5 None None None 161870659 Common dca division cell wall protein NMCC_1729 51 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 161869058 Common - hydrolase, putative NMCC_0041 82 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 161870804 Common - hypothetical inner membrane protein NMCC_1886 15 None None None 161869162 Pathogen - hypothetical protein NMCC_0157 1 None None None 161869776 Pathogen - hypothetical protein NMCC_0799 1 None None None 161870776 Common dinG ATP-dependent DNA helicase NMCC_1858 129 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 161869453 Common - 6-pyruvoyl tetrahydrobiopterin synthase, putative NMCC_0464 108 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 161869557 Common pglE glycosyltransferase PglE NMCC_0572 12 None None None 161870238 Common - ATP-dependent RNA helicase, putative NMCC_1279 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 161869408 Common pilQ type IV pilus assembly protein PilQ NMCC_0416 138 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 161870986 Pathogen - hypothetical protein NMCC_2081 1 None None None 161869089 Common synX polysialic acid capsule biosynthesis protein SynX NMCC_0078 85 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 161869669 Common pheT phenylalanyl-tRNA synthetase beta chain NMCC_0687 245 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 161869166 Common truA tRNA pseudouridine synthase NMCC_0161 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 161870131 Common - hypothetical protein NMCC_1170 109 COG2606 EbsC, Uncharacterized conserved protein Function unknown 161869492 Common ubiB ubiquinone biosynthesis protein NMCC_0505 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 161869660 Common hemH ferrochelatase NMCC_0677 156 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 161871000 Pathogen - hypothetical protein NMCC_2096 2 None None None 161869867 Common sucA 2-oxoglutarate dehydrogenase E1 component NMCC_0898 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 161869097 Common rfbB2 dTDP-D-glucose 4,6-dehydratase NMCC_0087 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 161870415 Common glpR glycerol 3-phosphate regulon repressor NMCC_1463 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 161870860 Pathogen - hypothetical protein NMCC_1947 1 None None None 161870500 Pathogen - hypothetical protein NMCC_1557 1 None None None 161870146 Common - periplasmic protein NMCC_1185 17 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 161870709 Common - MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG NMCC_1781 109 None None None 161870391 Common dapE succinyl-diaminopimelate desuccinylase NMCC_1438 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 161870771 Common - hypothetical protein NMCC_1852 12 COG1432 COG1432, Uncharacterized conserved protein Function unknown 161869662 Common thrS threonyl-tRNA synthetase NMCC_0680 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869206 Common glnB nitrogen regulatory protein P-II 1 NMCC_0210 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 161869994 Common - hypothetical protein NMCC_1027 12 None None None 161870115 Common hflX GTP-binding protein NMCC_1154 211 COG2262 HflX, GTPases General function prediction only 161870163 Common - type-II restriction endonuclease NMCC_1202 14 None None None 161870292 Common - IS1106 transposase NMCC_1334 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869182 Common - integral membrane protein NMCC_0179 79 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 161869934 Common abcZ ABC transporter ATP-binding protein NMCC_0966 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 161869951 Common - integral membrane protein NMCC_0984 14 COG3235 COG3235, Predicted membrane protein Function unknown 161869065 Pathogen - hypothetical protein NMCC_0048 1 None None None 161869709 Common lepB signal peptidase I NMCC_0729 204 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 161870924 Common rplL 50S ribosomal protein L7/L12 NMCC_2014 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 161869943 Common fbp fructose-1,6-bisphosphatase NMCC_0976 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 161869241 Pathogen - hypothetical protein NMCC_0246 1 None None None 161869616 Pathogen - hypothetical protein NMCC_0632 1 None None None 161869425 Common - citrate transporter NMCC_0433 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 161870966 Common mqo malate:quinone oxidoreductase NMCC_2061 56 COG0579 COG0579, Predicted dehydrogenase General function prediction only 161869720 Pathogen - secreted protein NMCC_0740 2 None None None 161870973 Pathogen mafA adhesin NMCC_2068 1 None None None 161869883 Common - hypothetical protein NMCC_0914 5 None None None 161869480 Common dsbC thiol:disulphide interchange protein NMCC_0492 71 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 161870449 Common potD3 spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein NMCC_1504 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 161869702 Common pnp polyribonucleotide nucleotidyltransferase NMCC_0722 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 161869032 Common - integral membrane protein NMCC_0015 6 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 161869116 Common folD methylenetetrahydrofolate dehydrogenase/cyclohydrolase NMCC_0107 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 161869345 Common - lipoprotein NMCC_0351 3 None None None 161869609 Pathogen - hypothetical protein NMCC_0625 1 None None None 161870487 Common infB initiation factor IF2 NMCC_1543 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 161870789 Common recQ ATP-dependent DNA helicase NMCC_1871 208 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 161870306 Common - iron-sulphur protein NMCC_1348 97 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 161870859 Pathogen - hypothetical protein NMCC_1946 1 None None None 161869272 Pathogen atpI ATP synthase I NMCC_0277 1 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 161870468 Pathogen - hypothetical protein NMCC_1523 1 None None None 161870758 Common vapA virulence associated protein NMCC_1832 12 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161869300 Pathogen - hypothetical protein NMCC_0305 1 None None None 161869764 Common adk adenylate kinase NMCC_0784 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 161870502 Pathogen - hypothetical protein NMCC_1559 1 None None None 161870355 Common gabD succinate semialdehyde dehydrogenase NMCC_1399 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 161870473 Common - hypothetical protein NMCC_1529 82 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 161870526 Common tyrB aromatic amino acid aminotransferase NMCC_1591 75 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 161869383 Common lsp lipoprotein signal peptidase NMCC_0390 194 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161870087 Common rpe ribulose-phosphate 3-epimerase NMCC_1125 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 161870648 Common ftsA cell division protein NMCC_1718 185 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 161869309 Common - hypothetical protein NMCC_0314 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 161870066 Pathogen - transposase NMCC_1104 2 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161871018 Common etfB electron transfer flavoprotein beta-subunit NMCC_2114 100 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 161870835 Common - transmembrane transport protein NMCC_1917 24 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 161870910 Common rplV 50S ribosomal protein L22 NMCC_2000 224 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 161870339 Common trpS tryptophanyl-tRNA synthetase NMCC_1383 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870916 Common - transposase NMCC_2006 13 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869816 Common - integral membrane protein NMCC_0845 15 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 161869831 Pathogen - hypothetical protein NMCC_0862 1 None None None 161870824 Common - putative integral membrane protein NMCC_1906 30 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 161870675 Common - transcriptional regulator, ArsR family NMCC_1747 55 COG4742 COG4742, Predicted transcriptional regulator Transcription 161869730 Common - putative phage shock protein E precursor NMCC_0750 106 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 161869289 Common - myo-inositol-1(or 4)-monophosphatase NMCC_0294 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 161869694 Common bcp bacterioferritin comigratory protein NMCC_0714 205 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 161870211 Common - hydrolase NMCC_1251 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 161869874 Common - hypothetical protein NMCC_0905 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 161869676 Pathogen - chorismate--pyruvate lyase NMCC_0694 2 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 161870383 Pathogen - hypothetical protein NMCC_1429 1 None None None 161869184 Common - putative psedouridine synthase NMCC_0181 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 161870480 Common - opacity outermembrane protein NMCC_1536 7 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 161871030 Common hsdS type I restriction enzyme NMCC_0792 47 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 161870318 Common - hypothetical protein NMCC_1360 74 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 161869742 Common ftsH ATP-dependent zinc metallopeptidase NMCC_0762 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 161870015 Common - putative oxidoreductase NMCC_1048 47 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 161870870 Common rnhB ribonuclease HII NMCC_1958 237 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 161869809 Common rplY 50S ribosomal protein L25 NMCC_0838 196 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 161870615 Common - IS1106A3 transposase NMCC_1684 42 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870816 Common nuoG NADH dehydrogenase I chain G NMCC_1898 192 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 161869894 Common - chloride channel protein-related protein NMCC_0925 93 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 161869516 Pathogen - FrpC operon protein NMCC_0530 1 None None None 161869514 Common - bacteriocin resistance protein, putative NMCC_0528 13 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 161870103 Common - putative type I restriction enzyme NMCC_1142 130 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 161870668 Common - hypothetical protein NMCC_1740 2 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 161870584 Common natC periplasmic type I secretion system protein NMCC_1650 107 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161869041 Pathogen - pilS cassette NMCC_0024 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161870623 Common acpS holo-(acyl-carrier protein) synthase NMCC_1692 69 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 161869229 Common - hypothetical protein NMCC_0233 4 COG4316 COG4316, Uncharacterized protein conserved in bacteria Function unknown 161870953 Common - hypothetical protein NMCC_2047 2 None None None 161869744 Common - putative RNA-binding protein containing KH domain NMCC_0764 91 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 161869220 Common - hypothetical protein NMCC_0224 11 COG3177 COG3177, Uncharacterized conserved protein Function unknown 161870780 Common - hypothetical protein NMCC_1862 151 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 161870054 Pathogen - hypothetical protein NMCC_1090 1 None None None 161870243 Common clpX ATP-dependent Clp protease ATP-binding subunit NMCC_1284 240 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 161870852 Common - ferredoxin, 4Fe-4S bacterial type NMCC_1939 129 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 161870457 Common - two component response regulator NMCC_1512 213 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 161869596 Pathogen - hypothetical protein NMCC_0612 1 None None None 161869517 Common frpA1 iron-regulated protein FrpA, putative NMCC_0531 101 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 161869442 Pathogen - hypothetical protein NMCC_0453 1 None None None 161869727 Common - site-specific DNA-methyltransferase M.NgoVII NMCC_0747 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 161869792 Pathogen - hypothetical protein NMCC_0815 1 None None None 161869366 Common - hypothetical protein NMCC_0372 17 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 161869704 Pathogen - lipoprotein NMCC_0724 1 None None None 161870465 Common trkA potassium uptake protein NMCC_1520 138 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 161870663 Common mraW S-adenosyl-methyltransferase mraW NMCC_1733 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 161870440 Common - transcriptional regulator, MarR family NMCC_1489 23 COG1846 MarR, Transcriptional regulators Transcription 161869725 Common - putative stress-sensitive restriction system protein NMCC_0745 25 None None None 161869520 Common - ABC-transporter ATP-binding protein NMCC_0534 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 161870079 Pathogen - periplasmic protein NMCC_1117 1 None None None 161869460 Common nth endonuclease III NMCC_0472 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 161870579 Common - integral membrane protein NMCC_1645 99 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 161869824 Pathogen - hypothetical protein NMCC_0853 1 None None None 161870745 Common rpmA 50S ribosomal protein L27 NMCC_1819 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 161870697 Common - hypothetical protein NMCC_1769 2 COG1403 McrA, Restriction endonuclease Defense mechanisms 161870496 Common - IS1016 transposase NMCC_1553 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869078 Common dnaJ Chaperone protein dnaJ NMCC_0067 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 161870304 Common - hypothetical protein NMCC_1346 152 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 161869359 Common mdaB modulator of drug activity B NMCC_0365 43 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 161869175 Common gntP gluconate permease NMCC_0172 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 161869534 Common - nucleotide-binding protein NMCC_0548 226 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 161869415 Common cyc cytochrome C NMCC_0423 55 COG2863 COG2863, Cytochrome c553 Energy production and conversion 161870523 Common gcvP glycine dehydrogenase NMCC_1587 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 161869350 Pathogen - hypothetical protein NMCC_0356 1 None None None 161869468 Pathogen - hypothetical protein NMCC_0480 1 None None None 161870224 Common - hypothetical protein NMCC_1265 131 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 161869553 Common pgp phosphoglycolate phosphatase NMCC_0568 147 COG0546 Gph, Predicted phosphatases General function prediction only 161870000 Common - hypothetical protein NMCC_1033 16 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 161870684 Common - ABC transporter ATP-binding protein NMCC_1756 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 161869926 Common - transposase NMCC_0958 114 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870031 Pathogen - periplasmic protein NMCC_1064 1 None None None 161870251 Pathogen - hypothetical protein NMCC_1292 1 None None None 161869256 Common - inner membrane protein NMCC_0261 19 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 161869710 Common lepA GTP-binding protein NMCC_0730 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 161870151 Common gcr site-specific recombinase NMCC_1190 23 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 161869845 Common - cytidine and deoxycytidylate deaminase family protein NMCC_0876 220 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 161869083 Common galE UDP-glucose 4-epimerase NMCC_0072 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 161869072 Common proC pyrroline-5-carboxylate reductase NMCC_0055 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 161869437 Pathogen - hypothetical protein NMCC_0447 1 None None None 161869833 Common - C-type cytochrome NMCC_0864 24 COG3909 COG3909, Cytochrome c556 Energy production and conversion 161870692 Common - inorganic phosphate transporter, PiT family NMCC_1764 171 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 161869455 Common - hypothetical protein NMCC_0466 167 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 161869302 Common plsX fatty acid/phospholipid biosynthesis protein NMCC_0307 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 161870019 Common - hypothetical protein NMCC_1052 2 None None None 161870731 Common - inner membrane hypothetical protein NMCC_1804 3 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 161870888 Common - integral membrane protein NMCC_1977 98 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 161870365 Common scpA segregation and condensation protein A NMCC_1409 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 161870600 Common bioC biotin synthesis protein BioC, putative NMCC_1668 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 161869543 Common potA1 spermidine/putrescine ABC transporter, ATP-binding protein NMCC_0557 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 161870681 Common mapA maltose phosphorylase NMCC_1753 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 161870630 Pathogen - hypothetical protein NMCC_1699 1 None None None 161870155 Common mfd transcription-repair coupling factor NMCC_1194 226 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 161870513 Common - hypothetical protein NMCC_1576 3 None None None 161869573 Pathogen - hypothetical protein NMCC_0588 1 None None None 161870444 Pathogen - hypothetical protein NMCC_1499 1 None None None 161870833 Common - hypothetical protein NMCC_1915 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 161870820 Common nuoD NADH dehydrogenase I chain D NMCC_1902 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 161870904 Common rplE 50S ribosomal protein L5 NMCC_1994 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 161870028 Pathogen - hypothetical protein NMCC_1061 1 None None None 161870797 Common - hypothetical protein NMCC_1879 5 COG3212 COG3212, Predicted membrane protein Function unknown 161870313 Common - hypothetical protein NMCC_1355 186 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 161869641 Common trpB tryptophan synthase beta chain NMCC_0658 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 161870607 Common aspS aspartyl-tRNA synthetase NMCC_1676 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869192 Common - YhbX/YhjW/YijP/YjdB family protein NMCC_0195 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 161870872 Common - chromosome partitioning protein, ParA family protein NMCC_1960 205 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 161869987 Pathogen - hypothetical protein NMCC_1020 1 None None None 161869274 Common atpE ATP synthase C chain NMCC_0279 55 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 161870193 Pathogen - hypothetical protein NMCC_1233 1 None None None 161870203 Common - tRNA (guanine-N(7)-)-methyltransferase NMCC_1243 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 161870856 Common - lipoprotein NMCC_1943 54 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 161869333 Common - ferric siderophore receptor protein NMCC_0339 93 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 161869901 Pathogen - hypothetical protein NMCC_0933 1 None None None 161869814 Common cysT sulfate ABC transporter, permease protein NMCC_0843 230 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 161869264 Common - D-methionine transport system ATP-binding protein NMCC_0269 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 161870320 Common fpr2 ferredoxin--NADP reductase NMCC_1362 106 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 161869712 Common pilT2 twitching motility protein NMCC_0732 217 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 161870110 Common thrC threonine synthase NMCC_1149 162 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 161870827 Common - hypothetical protein NMCC_1909 8 None None None 161870639 Common nsrR nitric oxide-sensitive repressor NMCC_1709 146 COG1959 COG1959, Predicted transcriptional regulator Transcription 161870090 Common ribC riboflavin synthase alpha subunit NMCC_1128 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 161870518 Common pqiB pqiB protein NMCC_1582 59 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 161869428 Common grxC glutaredoxin 3 NMCC_0436 117 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 161869477 Common pilV1 type IV pilus assembly protein NMCC_0489 55 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 161869586 Common mafB2 adhesin MafB2 NMCC_0602 3 None None None 161869216 Common thdF thiophene and furan oxidation protein NMCC_0220 220 COG0486 ThdF, Predicted GTPase General function prediction only 161869101 Common lipB capsule polysaccharide modification protein NMCC_0091 31 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 161870581 Common grxB glutaredoxin 2 NMCC_1647 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 161869456 Common - hexosaminidase NMCC_0468 176 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 161870843 Common acpP acyl carrier protein NMCC_1925 207 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161869771 Common clpA ATP-dependent Clp protease ATP-binding subunit ClpA NMCC_0794 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 161869421 Common - IS1016 transposase NMCC_0429 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870372 Common rpiA ribose 5-phosphate isomerase A NMCC_1416 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 161869954 Common proB glutamate 5-kinase NMCC_0987 194 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 161869203 Common mgtE magnesium transporter NMCC_0206 173 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 161870077 Common lolD putative lipoprotein releasing factor ATP-binding protein NMCC_1115 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 161870428 Common argF ornithine transcarbamoylase NMCC_1476 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 161870463 Common hisJ polar amino acid transport system substrate-binding protein NMCC_1518 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 161870421 Common purN phosphoribosylglycinamide transformylase NMCC_1469 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 161870749 Common rpmB 50S ribosomal protein L28 NMCC_1823 170 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 161870802 Common xseB exodeoxyribonuclease small subunit NMCC_1884 70 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 161869890 Common pntB NAD(P) transhydrogenase beta subunit NMCC_0921 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 161870342 Pathogen - 4-oxalocrotonate tautomerase, putative NMCC_1386 1 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 161869602 Common - oxygen-independent coproporphyrinogen III oxidase NMCC_0618 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 161870377 Common ackA1 acetate kinase NMCC_1423 162 COG0282 ackA, Acetate kinase Energy production and conversion 161869684 Pathogen - hypothetical protein NMCC_0704 1 None None None 161870725 Common - BolA/YrbA family protein NMCC_1798 73 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 161870400 Common - IS1106A3 transposase NMCC_1447 32 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870172 Common rsuA ribosomal small subunit pseudouridine synthase A NMCC_1211 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 161869025 Common ftsE ABC transporter ATP-binding protein NMCC_0007 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 161870703 Pathogen - hypothetical protein NMCC_1775 1 None None None 161869141 Common petC cytochrome C1 precursor NMCC_0135 78 COG2857 CYT1, Cytochrome c1 Energy production and conversion 161870360 Pathogen - hypothetical protein NMCC_1404 1 None None None 161870657 Pathogen - periplasmic protein NMCC_1727 1 None None None 161869160 Pathogen - hypothetical protein NMCC_0155 2 None None None 161870554 Common thyA thymidylate synthase NMCC_1620 145 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 161870186 Common ftsK2 cell division protein FtsK NMCC_1226 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 161869071 Pathogen - lipoprotein NMCC_0054 1 None None None 161870774 Common - LysR-family transcriptional regulator NMCC_1856 125 COG0583 LysR, Transcriptional regulator Transcription 161869778 Common - transposase, IS30 family NMCC_0801 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161869103 Common gltS sodium/glutamate symport carrier protein NMCC_0093 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 161869056 Common glmU UDP-N-acetylglucosamine pyrophosphorylase NMCC_0039 232 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 161869961 Common - hypothetical protein NMCC_0994 73 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 161869121 Common thiS thiamine biosynthesis protein ThiS NMCC_0115 17 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 161869664 Common rpmI 50S ribosomal protein L35 NMCC_0682 193 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 161870133 Common - hypothetical protein NMCC_1172 154 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 161869914 Pathogen - hypothetical protein NMCC_0946 1 None None None 161870144 Common algI putative polysaccharide modification protein NMCC_1183 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 161869250 Common - hypothetical protein NMCC_0255 6 None None None 161869872 Common sucD succinyl-CoA synthetase alpha subunit NMCC_0903 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 161870743 Common - octaprenyl-diphosphate synthase NMCC_1817 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 161869169 Common nlaB 1-acyl-SN-glycerol-3-phosphate acyltransferase NMCC_0164 184 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 161869923 Pathogen - hypothetical protein NMCC_0955 2 None None None 161869164 Common chpA1 PEMK-like protein NMCC_0159 50 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 161871002 Common - lipoprotein NMCC_2098 131 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 161869865 Common - hypothetical protein NMCC_0896 34 COG2938 COG2938, Uncharacterized conserved protein Function unknown 161869902 Common - IS1106 transposase NMCC_0934 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870984 Pathogen - hypothetical protein NMCC_2079 1 None None None 161869789 Common hisS2 histidyl-tRNA synthetase NMCC_0812 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870451 Common - hypothetical protein NMCC_1506 2 None None None 161869411 Common pilN type IV pilus assembly protein PilN NMCC_0419 39 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 161869931 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit NMCC_0963 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 161870613 Pathogen tbpB transferrin-binding protein B NMCC_1682 3 None None None 161869968 Pathogen - hypothetical protein NMCC_1001 1 None None None 161870716 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) NMCC_1789 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 161870432 Common ilvI acetolactate synthase isozyme III large subunit NMCC_1480 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 161869690 Common - regulator NMCC_0710 29 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 161870099 Common - hypothetical protein NMCC_1138 215 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 161870979 Pathogen - hypothetical protein NMCC_2074 1 None None None 161871003 Common - integral membrane protein NMCC_2099 5 COG2259 COG2259, Predicted membrane protein Function unknown 161870268 Common eda 2-keto-4-hydroxyglutarate aldolase NMCC_1309 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 161869501 Common nqrB Na(+)-translocating NADH-ubiquinone reductase subunit B NMCC_0514 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 161869913 Common - IS1106 transposase, putative NMCC_0945 36 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870083 Common - hypothetical protein NMCC_1121 108 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 161870673 Common - transposase NMCC_1745 49 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869144 Common - DNA ligase NMCC_0138 30 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 161870814 Common nuoI NADH dehydrogenase I chain I NMCC_1896 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 161869111 Common cysS cysteinyl-tRNA synthetase NMCC_0102 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870358 Pathogen - hypothetical protein NMCC_1402 5 COG2879 COG2879, Uncharacterized small protein Function unknown 161870899 Common rpmD 50S ribosomal protein L30 NMCC_1989 50 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 161869180 Common - hypothetical protein NMCC_0177 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 161871023 Common gapA2 glyceraldehyde 3-phosphate dehydrogenase C NMCC_2119 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 161870715 Common - hypothetical protein NMCC_1788 16 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 161869226 Common - transposition inhibitor protein NMCC_0230 17 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869886 Pathogen - hypothetical protein NMCC_0917 1 None None None 161870049 Pathogen - hypothetical protein NMCC_1085 1 None None None 161869357 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase NMCC_0363 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 161870567 Common - integral membrane protein NMCC_1633 65 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 161869853 Common rpmJ2 50S ribosomal protein L36 NMCC_0884 62 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 161869578 Common - ribonuclease inhibitor barstar NMCC_0594 6 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 161870869 Common gidA glucose inhibited division protein A NMCC_1957 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 161870891 Common minE cell division topological specificity factor NMCC_1980 82 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 161869966 Pathogen - hypothetical protein NMCC_0999 1 None None None 161869430 Common recG DNA helicase NMCC_0438 216 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 161870089 Common - hypothetical protein NMCC_1127 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 161869433 Pathogen - hypothetical protein NMCC_0441 1 None None None 161869138 Common - hypothetical protein NMCC_0132 104 COG0327 COG0327, Uncharacterized conserved protein Function unknown 161870646 Common - putative MFS transporter, AGZA family, xanthine/uracil permease NMCC_1716 136 COG2252 COG2252, Permeases General function prediction only 161869444 Pathogen - hypothetical protein NMCC_0455 1 None None None 161869396 Common pglD pilin glycosylation protein NMCC_0403 158 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 161869729 Common - periplasmic protein NMCC_0749 36 COG3439 COG3439, Uncharacterized conserved protein Function unknown 161870337 Pathogen - Ag473 NMCC_1381 1 None None None 161869243 Common - transcriptional regulator, AraC family NMCC_0248 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 161870923 Common rpoB DNA-directed RNA polymerase beta chain NMCC_2013 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 161870494 Pathogen - hypothetical protein NMCC_1550 1 None None None 161870862 Common rluC ribosomal large subunit pseudouridine synthase C NMCC_1950 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 161869674 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase NMCC_0692 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 161869053 Common - lipoprotein NMCC_0036 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 161870769 Common ffh signal recognition particle protein NMCC_1850 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 161869820 Common pilV type IV pilus assembly protein PilV NMCC_0849 6 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 161869881 Pathogen - hypothetical protein NMCC_0912 2 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869284 Common lgtA lacto-N-neotetraose biosynthesis glycosyl tranferase NMCC_0289 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 161869190 Common - transcriptional regulator, HTH_3 family NMCC_0193 60 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 161869888 Pathogen - cell-surface protein NMCC_0919 1 None None None 161871032 Common - stomatin/Mec-2 family protein NMCC_1100 202 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 161870822 Common nuoB NADH dehydrogenase I chain B NMCC_1904 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 161870559 Pathogen - hypothetical protein NMCC_1625 1 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 161869525 Common - hypothetical protein NMCC_0539 131 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 161869494 Common grpE molecular chaperone GrpE NMCC_0507 220 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 161870944 Common fmt methionyl-tRNA formyltransferase NMCC_2038 221 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 161869953 Common proA gamma-glutamyl phosphate reductase NMCC_0986 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 161869123 Common thiO D-amino acid oxidase flavoprotein, putative NMCC_0117 60 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 161869651 Pathogen - membrane protein NMCC_0668 1 None None None 161869851 Common - hypothetical protein NMCC_0882 75 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 161869310 Common rnpA ribonuclease P protein component NMCC_0315 45 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 161869945 Common - integral membrane protein NMCC_0978 155 COG0344 COG0344, Predicted membrane protein Function unknown 161869829 Pathogen - hypothetical protein NMCC_0860 1 None None None 161870165 Common nrdA ribonucleotide reductase I alpha chain NMCC_1204 206 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 161870219 Common - tRNA/rRNA methyltransferase NMCC_1260 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 161869624 Common ribE 6,7-dimethyl-8-ribityllumazine synthase NMCC_0641 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 161869631 Common purF amidophosphoribosyltransferase NMCC_0648 231 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 161870995 Common - sodium/dicarboxylate symporter family protein NMCC_2090 151 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 161870854 Common gapA1 glyceraldehyde 3-phosphate dehydrogenase NMCC_1941 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 161870653 Common ftsW cell division protein NMCC_1723 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 161869678 Common ptsN PTS system, nitrogen regulatory IIA protein NMCC_0696 136 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 161870829 Common - hypothetical protein NMCC_1911 9 None None None 161870486 Common nusA N utilisation substance protein A NMCC_1542 218 COG0195 NusA, Transcription elongation factor Transcription 161869614 Pathogen - hypothetical protein NMCC_0630 1 None None None 161870294 Common - integral membrane protein NMCC_1336 20 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 161870599 Pathogen - hypothetical protein NMCC_1667 1 None None None 161870756 Common - hypothetical protein NMCC_1830 17 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 161869039 Pathogen - hypothetical protein NMCC_0022 1 None None None 161870353 Pathogen - hypothetical protein NMCC_1397 1 None None None 161870528 Common aroC chorismate synthase NMCC_1593 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 161870308 Common - periplasmic protein NMCC_1350 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 161870914 Common rplD 50S ribosomal protein L4 NMCC_2004 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 161869766 Common rfaE ADP-heptose synthetase NMCC_0786 122 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 161870655 Common - periplasmic protein NMCC_1725 4 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 161869270 Common - transposase for IS1655 NMCC_0275 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161869539 Common secD protein-export membrane protein NMCC_0553 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 161869466 Common hemC porphobilinogen deaminase NMCC_0478 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 161870560 Common mtrE outer membrane lipoprotein NMCC_1626 124 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161869485 Pathogen - hypothetical protein NMCC_0498 1 None None None 161870536 Common ans L-asparaginase NMCC_1601 116 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 161870135 Common ppiA peptidyl-prolyl cis-trans isomerase A NMCC_1174 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 161870232 Common - oxalate/formate antiporter, putative NMCC_1273 88 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 161870989 Common - IS1016 transposase NMCC_2084 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870276 Common - ABC transporter family protein NMCC_1317 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 161870070 Common - hypothetical protein NMCC_1108 10 COG3737 COG3737, Uncharacterized conserved protein Function unknown 161869559 Common prfC peptide chain release factor 3 NMCC_0574 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 161870632 Common - IS1106A3 transposase NMCC_1701 33 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869787 Common engA GTP-binding protein engA NMCC_0810 228 COG1160 COG1160, Predicted GTPases General function prediction only 161869296 Common fabD malonyl CoA-acyl carrier protein transacylase NMCC_0301 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 161869541 Pathogen - hypothetical protein NMCC_0555 1 None None None 161870126 Common - periplasmic protein NMCC_1165 111 COG2353 COG2353, Uncharacterized conserved protein Function unknown 161870678 Common nadA quinolinate synthetase A NMCC_1750 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 161869023 Common arsC arsenate reductase NMCC_0005 100 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 161869473 Common - UDP-2,3-diacylglucosamine hydrolase NMCC_0485 76 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 161869085 Pathogen - hypothetical protein NMCC_0074 1 None None None 161870153 Pathogen - hypothetical protein NMCC_1192 1 None None None 161869236 Common groEL chaperonin 60kD subunit NMCC_0241 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 161870787 Common - hypothetical protein NMCC_1869 59 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 161869063 Common - signal recognition particle protein NMCC_0046 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 161869739 Common pth peptidyl-tRNA hydrolase NMCC_0759 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 161870569 Common fixP cb-type cytochrome c oxidase subunit III NMCC_1635 81 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 161870686 Common thiL thiamine-monophosphate kinase NMCC_1758 193 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 161869822 Common pilX type IV pilus assembly protein PilX NMCC_0851 2 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 161870381 Common - phytoene synthase-related protein NMCC_1427 93 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 161870257 Common gyrA DNA gyrase subunit A NMCC_1298 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 161869405 Common - hypothetical protein NMCC_0413 78 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 161870002 Pathogen - hypothetical protein NMCC_1035 1 None None None 161869740 Common - hypothetical protein NMCC_0760 69 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 161869807 Common lolB outer membrane lipoprotein LolB, putative NMCC_0832 26 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 161870609 Common - phospholipase A1, putative NMCC_1678 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 161870665 Common - hypothetical protein NMCC_1735 94 COG1565 COG1565, Uncharacterized conserved protein Function unknown 161870241 Pathogen - hypothetical protein NMCC_1282 1 None None None 161869523 Common rimM 16S rRNA processing protein NMCC_0537 185 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 161870951 Common - PhnO-related protein NMCC_2045 32 COG0456 RimI, Acetyltransferases General function prediction only 161869706 Pathogen - integral membrane protein NMCC_0726 1 None None None 161869594 Common - hypothetical protein NMCC_0610 3 None None None 161869992 Pathogen - hypothetical protein NMCC_1025 1 None None None 161870447 Pathogen - hypothetical protein NMCC_1502 1 None None None 161870225 Common gatC Glu-tRNA(Gln) amidotransferase subunit C NMCC_1266 60 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 161869512 Common nosL protein disulfide isomerase NosL, putative NMCC_0526 27 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 161870621 Common - secreted protein,Tou4 NMCC_1690 3 None None None 161869794 Pathogen - hypothetical protein NMCC_0817 1 None None None 161869722 Common hemX uroporphyrin-III C-methyltransferase HemX, putative NMCC_0742 53 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 161870602 Common bioF 8-amino-7-oxonoanoate synthase NMCC_1670 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 161870179 Common - nucleotide-binding protein NMCC_1219 97 COG1485 COG1485, Predicted ATPase General function prediction only 161869532 Common tatB sec-independent protein translocase component NMCC_0546 81 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 161869519 Common - ABC-transporter membrane protein NMCC_0533 115 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 161869368 Pathogen - hypothetical protein NMCC_0374 1 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 161869211 Common fetB iron(III) ABC transporter, periplasmic binding protein NMCC_0215 63 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 161869925 Pathogen - hypothetical protein NMCC_0957 1 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 161870906 Common rpsQ 30S ribosomal protein S17 NMCC_1996 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 161870546 Common - hypothetical protein NMCC_1611 2 None None None 161869257 Common sspA stringent starvation protein A NMCC_0262 109 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 161869892 Common pntA NAD(P) transhydrogenase alpha subunit NMCC_0923 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 161869410 Common pilO type IV pilus assembly protein PilO NMCC_0418 45 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 161869343 Common - ribosomal-protein-alanine acetyltransferase, putative NMCC_0349 163 COG0456 RimI, Acetyltransferases General function prediction only 161870105 Pathogen - hypothetical protein NMCC_1144 1 None None None 161870214 Common aceE pyruvate dehydrogenase E1 component NMCC_1254 147 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 161870112 Common fpr1 ferredoxin--NADP reductase NMCC_1151 111 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 161870100 Common ribB bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II NMCC_1139 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 161870760 Pathogen - hypothetical protein NMCC_1834 1 None None None 161870061 Pathogen - hypothetical protein NMCC_1097 1 None None None 161869417 Common - cytochrome c-type biogenesis protein, putative NMCC_0425 187 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 161869812 Common cysA sulphate permease ATP-binding protein NMCC_0841 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 161869796 Pathogen - hypothetical protein NMCC_0819 1 None None None 161870117 Common - hypothetical protein NMCC_1156 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 161870108 Common - integral membrane protein NMCC_1147 9 None None None 161870481 Common - hypothetical protein NMCC_1537 74 COG0778 NfnB, Nitroreductase Energy production and conversion 161870217 Common - hypothetical protein NMCC_1257 8 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 161869419 Common - lipid A biosynthesis lauroyl acyltransferase NMCC_0427 86 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 161870611 Common potD1 spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein NMCC_1680 125 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 161869413 Common ponA penicillin-binding protein 1 NMCC_0421 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 161869292 Common - hypothetical protein NMCC_0297 40 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870627 Common recO DNA repair protein (recombination protein o) NMCC_1696 67 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 161869105 Pathogen - hypothetical protein NMCC_0095 1 None None None 161870499 Common - periplasmic protein NMCC_1556 21 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 161870583 Common - transposase NMCC_1649 47 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870543 Common - hypothetical protein NMCC_1608 8 COG4899 COG4899, Uncharacterized protein conserved in bacteria Function unknown 161869791 Pathogen - hypothetical protein NMCC_0814 1 None None None 161869910 Common - oxidoreductase NMCC_0942 173 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 161869294 Common guaA GMP synthetase (glutamine-hydrolysing) NMCC_0299 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 161869362 Common - hypothetical protein NMCC_0368 8 None None None 161870248 Common - type III restriction/modification system enzyme NMCC_1289 9 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 161869522 Common trmD tRNA (guanine-N1)-methyltransferase NMCC_0536 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 161869919 Common - hypothetical protein NMCC_0951 8 None None None 161869899 Pathogen - hypothetical protein NMCC_0931 1 None None None 161869804 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase NMCC_0829 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 161869021 Common gltX glutamyl-tRNA synthetase NMCC_0003 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 161869201 Common - outer membrane protein precursor GNA2001 NMCC_0204 140 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 161870198 Common rpsF 30S ribosomal protein S6 NMCC_1238 171 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 161869409 Common pilP type IV pilus assembly protein PilP NMCC_0417 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 161869708 Common - integral membrane protein NMCC_0728 71 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 161870047 Pathogen - hypothetical protein NMCC_1083 1 None None None 161870035 Common ilvD dihydroxy-acid dehydratase NMCC_1068 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 161870637 Common - hypothetical integral membrane protein NMCC_1707 56 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 161870688 Common cysB putative cysteine transcriptional regulatory protein, activator NMCC_1760 183 COG0583 LysR, Transcriptional regulator Transcription 161869550 Common rho transcription termination factor NMCC_0565 204 COG1158 Rho, Transcription termination factor Transcription 161869471 Common - hypothetical protein NMCC_0483 21 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 161870492 Common - hypothetical protein NMCC_1548 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 161870006 Pathogen - hypothetical protein NMCC_1039 2 None None None 161870755 Common - hypothetical protein NMCC_1829 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 161870056 Common - hypothetical protein NMCC_1092 56 None None None 161869785 Common - periplasmic protein NMCC_0808 2 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 161871028 Common rpsH 30S ribosomal protein S8 NMCC_1992a 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 161870234 Common nadE NH(3)-dependent NAD synthetase NMCC_1275 207 COG0171 NadE, NAD synthase Coenzyme metabolism 161869593 Common - hypothetical protein NMCC_0609 2 None None None 161870022 Pathogen - hypothetical protein NMCC_1055 1 None None None 161870784 Common - hypothetical protein NMCC_1866 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 161870040 Common cysH phosphoadenosine phosphosulfate reductase NMCC_1073 162 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 161870588 Common - hypothetical protein NMCC_1655 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 161869451 Common - aluminum resistance protein, putative NMCC_0462 174 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 161869068 Common pilU twitching motility protein PilU NMCC_0051 205 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 161870938 Common dprA DNA processing chain A NMCC_2032 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 161869828 Common - IS1106A3 transposase NMCC_0859 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870539 Common folP dihydropteroate synthase NMCC_1604 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 161869465 Common - magnesium and cobalt transporter NMCC_0477 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 161870123 Common - DNA (cytosine-5-)-methyltransferase NMCC_1162 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 161869177 Common - putative carbonic anhydrase NMCC_0174 40 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 161870250 Common - conserved hypothetical DNA-binding protein NMCC_1291 127 COG1959 COG1959, Predicted transcriptional regulator Transcription 161870931 Common - ferredoxin, 4Fe-4S bacterial type NMCC_2025 120 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 161869445 Pathogen - hypothetical protein NMCC_0456 3 COG3792 COG3792, Uncharacterized protein conserved in bacteria Function unknown 161869819 Pathogen fimT fimbrial protein FimT NMCC_0848 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 161870387 Common rfaF ADP-heptose:LPS heptosyltransferase II NMCC_1433 104 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 161869348 Common dxs 1-deoxyxylulose-5-phosphate synthase NMCC_0354 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 161869611 Common - periplasmic protein NMCC_0627 3 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 161869760 Pathogen - hypothetical protein NMCC_0780 1 None None None 161869188 Common - hypothetical protein NMCC_0191 2 None None None 161870167 Pathogen - hypothetical protein NMCC_1206 1 None None None 161870826 Common - IS1016 transposase NMCC_1908 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869858 Common - peroxiredoxin 2 family protein/glutaredoxin NMCC_0889 106 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 161870085 Pathogen - hypothetical protein NMCC_1123 1 None None None 161870812 Common nuoK NADH dehydrogenase I chain K NMCC_1894 164 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 161869044 Pathogen - pilS cassette NMCC_0027 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161870351 Common surE 5'-nucleotidase surE NMCC_1395 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 161870301 Common - lipoprotein NMCC_1343 142 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 161869879 Common trpD anthranilate phosphoribosyltransferase NMCC_0910 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 161870188 Pathogen - hypothetical protein NMCC_1228 1 None None None 161870017 Common hscA chaperone protein HscA NMCC_1050 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 161869980 Common - E16-related protein NMCC_1013 9 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 161870296 Common porA porin, class I outer membrane protein NMCC_1338 31 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 161869946 Common folB dihydroneopterin aldolase NMCC_0979 89 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 161870226 Common gatA Glu-tRNA(Gln) amidotransferase subunit A NMCC_1267 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 161869399 Common pglB2 pilin glycosylation protein PglB2 NMCC_0406 182 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 161870472 Common - hypothetical protein NMCC_1528 70 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 161869721 Common hemD uroporphyrinogen-III synthase HemD, putative NMCC_0741 36 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 161870160 Common ftsB cell division protein FtsB NMCC_1199 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 161869247 Common - periplasmic transport protein NMCC_0252 72 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 161871014 Common purD phosphoribosylamine--glycine ligase NMCC_2110 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 161870679 Common nadB L-aspartate oxidase NMCC_1751 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 161870949 Common pyrI aspartate carbamoyltransferase regulatory chain NMCC_2043 62 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 161870178 Common esd esterase D NMCC_1218 96 COG0627 COG0627, Predicted esterase General function prediction only 161870963 Common map methionine aminopeptidase NMCC_2058 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 161870737 Common pilG type IV pilus assembly protein NMCC_1810 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 161869060 Common - integral membrane protein NMCC_0043 179 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 161870479 Common - pilS cassette NMCC_1535 5 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161869630 Common greB transcription elongation factor NMCC_0647 180 COG0782 GreA, Transcription elongation factor Transcription 161869369 Common pilC1 type IV pilus assembly protein NMCC_0375 33 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 161869835 Common - acyl CoA thioester hydrolase family protein NMCC_0866 130 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 161870157 Common kdsA 2-dehydro-deoxyphosphooctonate aldolase NMCC_1196 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 161869529 Common - hypothetical protein NMCC_0543 12 COG3308 COG3308, Predicted membrane protein Function unknown 161870998 Common - IS1106A3 transposase NMCC_2093 32 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869038 Pathogen - hypothetical protein NMCC_0021 1 None None None 161870097 Pathogen - hypothetical protein NMCC_1136 1 None None None 161869446 Pathogen - hypothetical protein NMCC_0457 1 None None None 161870918 Common tufA1 elongation factor TU NMCC_2008 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 161870335 Common - hypothetical protein NMCC_1379 12 None None None 161869434 Common - hypothetical protein NMCC_0442 6 COG2850 COG2850, Uncharacterized conserved protein Function unknown 161869588 Common - hypothetical protein NMCC_0604 2 COG1403 McrA, Restriction endonuclease Defense mechanisms 161869671 Pathogen - hypothetical protein NMCC_0689 1 None None None 161869605 Common ampD anhydro-N-acetylmuramyl-tripeptide amidase NMCC_0621 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 161870670 Common - hypothetical protein NMCC_1742 19 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 161869571 Common galU UTP--glucose-1-phosphate uridylyltransferase NMCC_0586 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 161870912 Common rplB 50S ribosomal protein L2 NMCC_2002 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 161869484 Common - IS1106 transposase NMCC_0497 37 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869870 Pathogen - membrane protein NMCC_0901 1 None None None 161870169 Common fpg formamidopyrimidine-DNA glycosylase NMCC_1208 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 161870062 Common - hypothetical protein NMCC_1098 39 COG2921 COG2921, Uncharacterized conserved protein Function unknown 161869330 Common pcm protein-L-isoaspartate O-methyltransferase NMCC_0336 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 161870191 Common pssA CDP-diacylglycerol--serineO-phosphatidyltransferse NMCC_1231 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 161869136 Common rpsI 30S ribosomal protein S9 NMCC_0130 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 161869989 Pathogen - hypothetical protein NMCC_1022 1 None None None 161870408 Common pyrG CTP synthase NMCC_1456 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 161869051 Common - membrane-bound lytic murein transglycosylase NMCC_0034 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 161869654 Common rpoH RNA polymerase sigma-32 factor NMCC_0671 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 161870831 Pathogen - hypothetical protein NMCC_1913 1 None None None 161870746 Common - monooxygenase NMCC_1820 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 161870229 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase, putative NMCC_1270 152 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 161870422 Common - peptidyl-prolyl isomerase NMCC_1470 131 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 161869656 Common - hypothetical protein NMCC_0673 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 161869773 Common cspA transcriptional regulator NMCC_0796 180 COG1278 CspC, Cold shock proteins Transcription 161870404 Pathogen - hypothetical protein NMCC_1451 1 None None None 161869200 Common - hypothetical protein NMCC_0203 8 None None None 161870898 Common secY preprotein translocase SECY subunit NMCC_1988 249 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 161869125 Common tldD TldD -like protein NMCC_0119 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 161869755 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase NMCC_0775 193 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 161870801 Common engC Probable GTPase engC NMCC_1883 164 COG1162 COG1162, Predicted GTPases General function prediction only 161870374 Common dnaQ DNA polymerase III, epsilon subunit NMCC_1419 140 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 161871022 Pathogen - hypothetical protein NMCC_2118 1 None None None 161869371 Common - periplasmic thioredoxin NMCC_0378 24 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 161870004 Common - hypothetical protein NMCC_1037 12 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 161870411 Common - hypothetical protein NMCC_1459 76 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 161870629 Common - bicyclomycin resistance protein, putative NMCC_1698 160 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 161870719 Pathogen - hypothetical protein NMCC_1792 1 None None None 161870333 Common - hypothetical protein NMCC_1377 39 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870433 Common - lipoprotein NMCC_1482 115 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 161869386 Common - IS1106A3 transposase NMCC_0393 37 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869391 Common dnaE DNA polymerase III, alpha subunit NMCC_0398 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 161870396 Common - hypothetical protein NMCC_1443 5 None None None 161870866 Pathogen - hypothetical protein NMCC_1954 1 None None None 161870181 Common - hypothetical protein NMCC_1221 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 161870235 Common - regulator of cell morphogenesis and NO signaling NMCC_1276 41 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 161870461 Pathogen - hypothetical protein NMCC_1516 1 None None None 161870733 Common ilvE branched-chain amino acid aminotransferase NMCC_1806 210 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 161870545 Pathogen - hypothetical protein NMCC_1610 1 None None None 161870857 Common fur ferric uptake regulation protein NMCC_1944 200 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 161869658 Pathogen - hypothetical protein NMCC_0675 1 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 161869562 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase NMCC_0577 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 161869862 Common sdhD succinate dehydrogenase hydrophobic membrane anchor protein NMCC_0893 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 161870429 Common ilvC ketol-acid reductoisomerase NMCC_1477 211 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 161869860 Pathogen - hypothetical protein NMCC_0891 1 None None None 161870878 Common cdsA phosphatidate cytidylyltransferase NMCC_1967 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 161870982 Pathogen - hypothetical protein NMCC_2077 1 None None None 161870595 Common - hypothetical protein NMCC_1663 9 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 161869381 Common ribF riboflavin kinase/FMN adenylyltransferase NMCC_0388 211 COG0196 RibF, FAD synthase Coenzyme metabolism 161869317 Common mlp lipoprotein NMCC_0322 9 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 161869157 Pathogen - hypothetical protein NMCC_0152 1 None None None 161869403 Common ribD diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase NMCC_0411 230 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 161870450 Common alaS alanyl-tRNA synthetase NMCC_1505 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870643 Common acnA aconitate hydratase NMCC_1713 223 COG1048 AcnA, Aconitase A Energy production and conversion 161870125 Common leuB 3-isopropylmalate dehydrogenase NMCC_1164 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 161869497 Common nqrF Na(+)-translocating NADH-ubiquinone reductase subunit F NMCC_0510 167 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 161869848 Common - hypothetical protein NMCC_0879 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 161869332 Pathogen - hypothetical protein NMCC_0338 1 None None None 161869869 Common lpdA3 dihydrolipoamide dehydrogenase E3 component NMCC_0900 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 161869666 Common pheS phenylalanyl-tRNA synthetase alpha chain NMCC_0684 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 161870864 Common rne ribonuclease E NMCC_1952 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 161871004 Pathogen - periplasmic protein NMCC_2100 1 None None None 161870285 Common fis factor-for-inversion-stimulation protein NMCC_1326 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 161870562 Common mtrC membrane fusion protein NMCC_1628 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 161869252 Common - periplasmic protein NMCC_0257 165 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 161870038 Common cysN sulphate adenylate transferase subunit 1 NMCC_1071 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 161870136 Common - CobW-related protein NMCC_1175 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 161869737 Common ppiB peptidyl-prolyl cis-trans isomerase B NMCC_0757 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 161869577 Pathogen - hypothetical protein NMCC_0593 1 None None None 161870739 Common - Dephospho-CoA kinase (Dephosphocoenzyme A kinase) NMCC_1812 201 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 161870068 Pathogen - hypothetical protein NMCC_1106 1 None None None 161870507 Common rpoZ DNA-directed RNA polymerase omega chain NMCC_1570 111 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 161870705 Pathogen - hypothetical protein NMCC_1777 1 None None None 161869214 Pathogen - hypothetical protein NMCC_0218 1 None None None 161870706 Pathogen frpC iron-regulated protein FrpC NMCC_1778 1 None None None 161869637 Common - hypothetical protein NMCC_0654 7 None None None 161870946 Common - periplasmic protein NMCC_2040 47 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 161870208 Common creA creA protein NMCC_1248 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 161869713 Common holB DNA polymerase III, delta' subunit NMCC_0733 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 161870142 Common - mercury transport periplasmic protein, putative NMCC_1181 55 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 161870273 Common sodC superoxide dismutase NMCC_1314 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 161870903 Common rpsN 30S ribosomal protein S14 NMCC_1993 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 161869622 Common pyrC dihydroorotase NMCC_0639 99 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 161870293 Common lysS lysyl-tRNA synthetase NMCC_1335 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 161869304 Common rpmF 50S ribosomal protein L32 NMCC_0309 110 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 161870845 Common pglA glycosyltransferase NMCC_1927 182 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 161869237 Common - hypothetical periplasmic protein NMCC_0242 12 None None None 161869598 Common trkH trk system potassium uptake protein TrkH NMCC_0614 132 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 161869259 Pathogen - hypothetical protein NMCC_0264 1 None None None 161869546 Pathogen - hypothetical protein NMCC_0561 1 None None None 161869095 Common - site-specific DNA methylase NMCC_0085 8 COG3392 COG3392, Adenine-specific DNA methylase DNA replication, recombination, and repair 161870484 Common serC phosphoserine aminotransferase NMCC_1540 110 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 161870552 Common - hypothetical protein NMCC_1618 38 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 161870726 Common - hypothetical protein NMCC_1799 68 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 161869112 Common exoA exodeoxyribonuclease NMCC_0103 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 161870791 Pathogen - hypothetical protein NMCC_1873 1 None None None 161871038 Common prsA ribose-phosphate pyrophosphokinase NMCC_0837 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 161870075 Common - hypothetical protein NMCC_1113 111 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 161870808 Common - hypothetical protein NMCC_1890 20 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 161870838 Common glnE glutamate-ammonia-ligase adenylyltransferase NMCC_1920 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 161870795 Common - tRNA/rRNA methyltransferase NMCC_1877 166 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 161869328 Common tpi triosephosphate isomerase NMCC_0334 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 161870571 Common fixO cb-type cytochrome c oxidase subunit II NMCC_1637 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 161869321 Pathogen - leucyl-tRNA synthetase NMCC_0326 1 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870515 Common - hypothetical protein NMCC_1578 13 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 161869230 Common - hypothetical inner membrane protein NMCC_0234 117 COG2855 COG2855, Predicted membrane protein Function unknown 161870575 Common exbD biopolymer transport protein NMCC_1641 139 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 161869648 Common - hypothetical protein NMCC_0665 165 COG1496 COG1496, Uncharacterized conserved protein Function unknown 161869199 Pathogen - hypothetical protein NMCC_0202 1 None None None 161869887 Pathogen - hypothetical protein NMCC_0918 1 None None None 161870423 Common holC DNA polymerase III chi subunit NMCC_1471 29 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 161870322 Common - 2-nitropropane dioxygenase NMCC_1366 78 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 161870604 Common - C4-dicarboxylate transporter NMCC_1672 88 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 161869458 Common - integral membrane protein NMCC_0470 52 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 161870683 Common - sugar transporter, putative NMCC_1755 37 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 161870690 Common hemN oxygen-independent coproporphyrinogen III oxidase NMCC_1762 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 161869530 Common - Maf/YceF/YhdE family protein NMCC_0544 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 161869299 Pathogen - hypothetical protein NMCC_0304 1 None None None 161869810 Common - D-alanyl-D-alanine carboxypeptidase NMCC_0839 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 161870119 Common gshA glutamate--cysteine ligase NMCC_1158 27 None None None 161869912 Pathogen - hypothetical protein NMCC_0944 1 None None None 161869581 Pathogen - hypothetical protein NMCC_0597 1 None None None 161869143 Common - hydrolase NMCC_0137 217 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 161870549 Common lgtF beta-1,4-glucosyltransferase NMCC_1615 123 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 161869265 Common - D-methionine transport system permease protein NMCC_0270 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 161869279 Common atpD ATP synthase beta chain NMCC_0284 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 161869508 Common gcvH glycine cleavage system component H NMCC_0521 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 161870817 Common - putative endonuclease NMCC_1899 33 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 161870364 Common - HesA/MoeB/ThiF family protein NMCC_1408 175 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 161871010 Pathogen - hypothetical protein NMCC_2106 1 None None None 161870051 Common - transcriptional regulator NMCC_1087 37 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 161870033 Common bioB biotin synthase NMCC_1066 178 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 161870254 Common - iron-sulfur cofactor synthesis protein nifU-like protein NMCC_1295 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 161869225 Common - IS1106A3 transposase NMCC_0229 43 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869509 Common hemA glutamyl-tRNA reductase NMCC_0522 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 161869698 Pathogen - hypothetical protein NMCC_0718 1 None None None 161870525 Common - cytochrome c5 NMCC_1589 44 COG3245 CycB, Cytochrome c5 Energy production and conversion 161869093 Common ctrD capsule polysaccharide export ATP-binding protein NMCC_0082 248 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 161870298 Pathogen - hypothetical protein NMCC_1340 1 None None None 161870933 Pathogen - hypothetical protein NMCC_2027 3 None None None 161869906 Common - macrophage infectivity potentiator-related protein NMCC_0938 64 COG2128 COG2128, Uncharacterized conserved protein Function unknown 161869402 Common - lipopolysaccharide biosynthesis translocase NMCC_0410 10 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 161870058 Common - modification methylase (cytosine-specific DNA methylase) NMCC_1094 99 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 161869607 Common tmk thymidylate kinase NMCC_0623 222 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 161869440 Common - hypothetical protein NMCC_0451 6 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 161870520 Common tag DNA-3-methyladenine glycosylase I NMCC_1584 131 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 161869179 Common - hypothetical protein NMCC_0176 194 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 161869837 Common - opacity protein NMCC_0868 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 161870917 Common rpsJ 30S ribosomal protein S10 NMCC_2007 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 161870618 Common amiC N-acetylmuramoyl-L-alanine amidase NMCC_1687 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 161870456 Common - two component sensor kinase NMCC_1511 80 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 161870128 Common - integral membrane protein NMCC_1167 15 None None None 161869066 Common pilC2 pilus-associated protein NMCC_0049 33 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 161869086 Pathogen siaD alpha-2,8 polysialyltransferase NMCC_0075 2 None None None 161869817 Common sodB superoxide dismutase NMCC_0846 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 161869354 Common accC acetyl-CoA carboxylase biotin carboxylase component NMCC_0360 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 161869482 Common - transposase NMCC_0495 54 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870883 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NMCC_1972 151 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 161870354 Common fimB fimbrial assembly protein NMCC_1398 9 None None None 161870490 Common - hemolysin, putative NMCC_1546 114 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 161870459 Common - hypothetical protein NMCC_1514 5 None None None 161870101 Common - hypothetical protein NMCC_1140 157 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 161870249 Common lldA L-lactate dehydrogenase NMCC_1290 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 161869802 Common - hypothetical protein NMCC_0825 77 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 161870928 Common nusG transcription antitermination protein NMCC_2018 215 COG0250 NusG, Transcription antiterminator Transcription 161869798 Pathogen - membrane protein NMCC_0821 1 None None None 161869301 Pathogen - hypothetical protein NMCC_0306 1 None None None 161870255 Common - HesB/YadR/YfhF family protein NMCC_1296 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 161869510 Common - NosR-related protein NMCC_0523 24 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 161870264 Common glk glucokinase NMCC_1305 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 161869107 Common - outer membrane protein P1, putative NMCC_0097 70 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 161870625 Pathogen - Tou3 NMCC_1694 1 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 161869566 Common fbpB iron(III) ABC transporter, permease protein NMCC_0581 204 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 161870341 Common - aminotransferase, class I NMCC_1385 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 161869290 Common - hypothetical protein NMCC_0295 45 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 161869600 Common - ribonuclease, putative NMCC_0616 193 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 161869364 Common - hypothetical protein NMCC_0370 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 161869318 Common leuS leucyl-tRNA synthetase NMCC_0323 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870810 Pathogen - hypothetical protein NMCC_1892 1 None None None 161869723 Common hemY HemY protein NMCC_0743 24 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 161870021 Common fdx ferredoxin, 2Fe-2S type NMCC_1054 64 COG0633 Fdx, Ferredoxin Energy production and conversion 161870956 Pathogen - integral membrane protein NMCC_2050 1 None None None 161869971 Common gam host-nuclease inhibitor protein NMCC_1004 7 COG4396 COG4396, Mu-like prophage host-nuclease inhibitor protein Gam General function prediction only 161869897 Common - hypothetical protein NMCC_0929 6 None None None 161870348 Pathogen - hypothetical protein NMCC_1392 1 None None None 161869800 Common - periplasmic protein NMCC_0823 3 None None None 161870175 Common hip integration host factor beta-subunit NMCC_1215 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 161870138 Common - low molecular weight protein tyrosine-phosphatase NMCC_1177 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 161870438 Common hisB imidazoleglycerol-phosphate dehydratase NMCC_1487 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 161870228 Common gatB Glu-tRNAGln amidotransferase subunit B NMCC_1269 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 161870667 Common dsbA1 thiol:disulfide interchange protein DsbA NMCC_1739 65 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 161870677 Common - cytoplasmic membrane protein NMCC_1749 64 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 161870259 Pathogen - transposase NMCC_1300 2 None None None 161870246 Common - hypothetical protein NMCC_1287 10 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 161869047 Common hprA glycerate dehydrogenase NMCC_0030 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 161869927 Common - hypothetical protein NMCC_0959 61 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 161869527 Common - two-component system regulator NMCC_0541 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 161870762 Common folA dihydrofolate reductase NMCC_1836 144 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 161869998 Common - I protein, putative NMCC_1031 23 COG4388 COG4388, Mu-like prophage I protein General function prediction only 161870974 Common mafB adhesin NMCC_2069 2 None None None 161869297 Common - integral membrane protein NMCC_0302 56 COG3326 COG3326, Predicted membrane protein Function unknown 161870150 Pathogen - hypothetical protein NMCC_1189 1 None None None 161871016 Common - hypothetical protein NMCC_2112 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 161870159 Common eno enolase NMCC_1198 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 161870651 Common murC UDP-N-acetylmuramate--alanine ligase NMCC_1721 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 161870685 Common pgpA phosphatidylglycerophosphatase A NMCC_1757 102 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 161869306 Common - Maf/YceF/YhdE family protein NMCC_0311 180 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 161870114 Common - P-type cation-transporting ATPase NMCC_1153 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 161869983 Pathogen - hypothetical protein NMCC_1016 1 None None None 161870497 Common - hypothetical protein NMCC_1554 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 161869360 Common crgA lysR-family transcriptional regulator NMCC_0366 166 COG0583 LysR, Transcriptional regulator Transcription 161869957 Common lgt prolipoprotein diacylglyceryl transferase NMCC_0990 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 161869748 Pathogen - hypothetical protein NMCC_0768 1 None None None 161870064 Common ung uracil-DNA glycosylase NMCC_1101 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 161869288 Common - hypothetical protein NMCC_0293 199 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 161869337 Common - araC-family transcriptional regulator NMCC_0343 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 161869948 Pathogen - hypothetical protein NMCC_0981 1 None None None 161870635 Common - nitrilase NMCC_1705 197 COG0388 COG0388, Predicted amidohydrolase General function prediction only 161869346 Common fba fructose-1,6-bisphosphate aldolase NMCC_0352 174 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 161869134 Common - hypothetical protein NMCC_0128 25 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 161870541 Common - hypothetical protein NMCC_1606 38 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 161869448 Pathogen - hypothetical protein NMCC_0459 1 None None None 161869099 Common rfbC2 dTDP-D-glucose 4,6-dehydratase NMCC_0089 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 161869751 Common - NAD+ kinase NMCC_0771 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 161869036 Pathogen - hypothetical protein NMCC_0019 1 None None None 161870303 Common agrA efflux transporter membrane protein AgrA NMCC_1345 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 161870380 Common - hypothetical protein NMCC_1426 23 None None None 161870121 Pathogen - lipoprotein NMCC_1160 1 None None None 161870385 Common - oxidoreductase, putative NMCC_1431 204 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 161869633 Common - colicin V production protein, putative NMCC_0650 38 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 161869081 Common rfbA probable glucose-1-phosphate thymidylyltransferase NMCC_0070 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 161869046 Pathogen - hypothetical protein NMCC_0029 1 COG3205 COG3205, Predicted membrane protein Function unknown 161869775 Common - hypothetical protein NMCC_0798 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 161870991 Common - CinA-related protein NMCC_2086 150 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 161870585 Common natD periplasmic type I secretion system protein NMCC_1651 115 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 161870921 Common rpsL 30S ribosomal protein S12 NMCC_2011 234 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 161869762 Pathogen - hypothetical protein NMCC_0782 1 None None None 161869826 Common - N-succinyldiaminopimelate aminotransferase NMCC_0855 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 161869877 Common - TonB-dependent receptor NMCC_0908 68 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 161870782 Common surA peptidyl-prolyl cis-trans isomerase NMCC_1864 162 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 161869627 Common era GTPase NMCC_0644 220 COG1159 Era, GTPase General function prediction only 161870753 Common - hypothetical protein NMCC_1827 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 161869635 Common folC bifunctional folylpolyglutamate synthase/dihydrofolate synthase NMCC_0652 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 161869991 Pathogen - hypothetical protein NMCC_1024 1 None None None 161870162 Common nrdB ribonucleoside diphosphate reductase I beta chain NMCC_1201 151 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 161871034 Common - putative transporter NMCC_1420 81 None None None 161870470 Common - hypothetical protein NMCC_1526 23 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 161870969 Pathogen - hypothetical protein NMCC_2064 1 None None None 161870477 Pathogen - pilS cassette NMCC_1533 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161870149 Common - high-affinity choline transport protein NMCC_1188 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 161870741 Common pilF type IV pilus assembly protein NMCC_1814 211 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 161869377 Common - GTP-binding protein, putative NMCC_0384 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 161869315 Common ppk polyphosphate kinase NMCC_0320 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 161870414 Common glnS glutaminyl-tRNA synthetase NMCC_1462 156 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 161869145 Common hpt hypoxanthine phosphoribosyltransferase NMCC_0139 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 161869452 Common - hypothetical protein NMCC_0463 13 None None None 161869575 Common ntpA nucleoside triphosphate pyrophosphohydrolase NMCC_0590 55 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 161869499 Common nqrD Na(+)-translocating NADH-ubiquinone reductase subunit D NMCC_0512 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 161869232 Pathogen - lipoprotein NMCC_0236 1 None None None 161869131 Common thiF 5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein NMCC_0125 217 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 161869783 Common - periplasmic protein NMCC_0806 20 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 161869168 Common - hypothetical protein NMCC_0163 142 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 161870036 Common cysI sulfite reductase hemoprotein, beta-component NMCC_1069 145 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 161870993 Pathogen - integral membrane protein NMCC_2088 1 None None None 161869155 Pathogen - putative integral membrane protein NMCC_0150 1 None None None 161870398 Common dnaG DNA primase NMCC_1445 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 161869207 Common - iron(III) ABC transporter, ATP-binding protein NMCC_0211 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 161870271 Pathogen - hypothetical protein NMCC_1312 1 None None None 161870641 Common ackA2 acetate kinase NMCC_1711 162 COG0282 ackA, Acetate kinase Energy production and conversion 161870701 Common - hypothetical protein NMCC_1773 13 None None None 161870708 Common - putative endonuclease NMCC_1780 61 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 161870772 Common - hypothetical protein NMCC_1854 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 161869977 Pathogen - hypothetical protein NMCC_1010 1 None None None 161870052 Common bfrB bacterioferritin B NMCC_1088 97 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 161870940 Common ntrY nitrogen regulation protein NtrY, putative NMCC_2034 220 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 161871006 Common - hypothetical protein NMCC_2102 13 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 161869339 Common argA acetylglutamate synthase NMCC_0345 199 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 161869668 Pathogen - hypothetical protein NMCC_0686 1 None None None 161870699 Pathogen - hypothetical protein NMCC_1771 2 None None None 161869186 Pathogen - type IV pilin-related protein NMCC_0189 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 161869735 Common - amino acid permease ATP-binding protein NMCC_0755 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 161869696 Common - bacterioferritin-associated ferredoxin, putative NMCC_0716 21 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 161870980 Pathogen - hypothetical protein NMCC_2075 1 None None None 161870406 Pathogen lbpB lactoferrin-binding protein NMCC_1453 3 COG5137 COG5137, Histone chaperone involved in gene silencing Transcription / Chromatin structure and dynamics 161870550 Common rfaK alpha 1,2 N-acetylglucosamine transferase NMCC_1616 210 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 161869240 Common aldA aldehyde dehydrogenase A NMCC_0245 223 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 161870394 Common - H.8 outer membrane protein NMCC_1441 19 COG3241 COG3241, Azurin Energy production and conversion 161869222 Pathogen - hypothetical protein NMCC_0226 1 None None None 161870140 Pathogen - hypothetical protein NMCC_1179 2 None None None 161869841 Common dapA dihydrodipicolinate synthase NMCC_0872 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 161871007 Common ecf ECF-family RNA polymerase sigma factor NMCC_2103 146 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 161870441 Common - integral membrane protein NMCC_1490 8 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 161870206 Common - hypothetical protein NMCC_1246 145 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 161869352 Common orn oligoribonuclease NMCC_0358 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 161869151 Common - thiamin pyrophosphokinase-related protein NMCC_0145 19 None None None 161869253 Common - hypothetical protein NMCC_0258 2 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 161869489 Common - transcriptional regulator NMCC_0502 51 COG2932 COG2932, Predicted transcriptional regulator Transcription 161869985 Pathogen - hypothetical protein NMCC_1018 2 None None None 161870616 Common glr glutamate racemase NMCC_1685 187 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 161869920 Pathogen - transcriptional regulator NMCC_0952 1 None None None 161870222 Pathogen - hypothetical protein NMCC_1263 1 None None None 161869393 Pathogen - hypothetical protein NMCC_0400 1 None None None 161869148 Common ptsI phosphoenolpyruvate-protein phosphotransferase NMCC_0142 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 161869746 Common - hypothetical protein NMCC_0766 81 COG1469 COG1469, Uncharacterized conserved protein Function unknown 161870798 Common ruvA Holliday junction DNA helicase NMCC_1880 212 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 161869552 Common - hypothetical protein NMCC_0567 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 161870435 Common - hypothetical protein NMCC_1484 4 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 161870183 Common - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NMCC_1223 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 161870764 Pathogen - hypothetical protein NMCC_1838 1 None None None 161870868 Common - amino-acid transport protein NMCC_1956 115 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 161869856 Common metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase NMCC_0887 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 161869996 Common - hypothetical protein NMCC_1029 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 161869929 Common sbp sulfate ABC transporter, periplasmic sulfate-binding protein NMCC_0961 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 161870279 Common frpA2 iron-regulated protein FrpA, putative NMCC_1320 101 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 161870896 Common rpsK 30S ribosomal protein S11 NMCC_1986 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 161870597 Common - hypothetical protein NMCC_1665 39 COG2229 COG2229, Predicted GTPase General function prediction only 161869564 Common - phosphate acyltransferase NMCC_0579 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 161869490 Common - hypothetical protein NMCC_0503 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 161869267 Common parB chromosome segregation protein NMCC_0272 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 161869582 Common - hypothetical protein NMCC_0598 4 None None None 161869962 Common - DnaA-related protein NMCC_0995 97 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 161870073 Common hupB DNA-binding protein NMCC_1111 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 161870577 Common tonB TonB protein NMCC_1643 21 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 161869646 Common - bile acid:Na+ symporter, BASS family NMCC_0663 75 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 161869109 Common - GTP-binding protein NMCC_0100 231 COG0536 Obg, Predicted GTPase General function prediction only 161869197 Common - hypothetical inner membrane protein NMCC_0200 82 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 161870881 Common omp85 outer membrane protein OMP85 NMCC_1970 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 161870573 Common - hypothetical protein NMCC_1639 56 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 161870425 Common pepA aminopeptidase A NMCC_1473 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 161870324 Common - ferredoxin, 4Fe-4S bacterial type NMCC_1368 76 COG0348 NapH, Polyferredoxin Energy production and conversion 161870095 Common purM phosphoribosylformylglycinamidine cyclo-ligase NMCC_1133 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 161869323 Pathogen - hypothetical protein NMCC_0328 1 None None None 161870346 Common - phosphatase NMCC_1390 177 COG0546 Gph, Predicted phosphatases General function prediction only 161870517 Common - PqiA family protein NMCC_1581 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 161869537 Common - histone deacetylase family protein NMCC_0551 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 161870793 Common - hydrolase NMCC_1875 131 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 161870996 Common - putative outer membrane protein NMCC_2091 124 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 161870369 Common - hypothetical protein NMCC_1413 4 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 161869277 Common atpA ATP synthase alpha chain NMCC_0282 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 161870086 Common ruvB Holliday junction DNA helicase NMCC_1124 233 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 161869506 Common - AsnC-family transcriptional regulator NMCC_0519 165 COG1522 Lrp, Transcriptional regulators Transcription 161870836 Common - hypothetical protein NMCC_1918 144 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 161870237 Common - hypothetical protein NMCC_1278 140 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 161870230 Common pdxH pyridoxamine-5'-phosphate oxidase NMCC_1271 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 161869463 Common gluP MFS transporter, FHS family, L-fucose permease NMCC_0475 56 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 161870326 Common tkt transketolase NMCC_1370 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 161870750 Pathogen - hypothetical protein NMCC_1824 1 None None None 161871012 Common - putative translation factor NMCC_2108 178 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 161869057 Pathogen - lipoprotein NMCC_0040 1 None None None 161869905 Common - acyl-CoA dehydrogenase family protein NMCC_0937 129 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 161869830 Common icd isocitrate dehydrogenase NMCC_0861 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 161869212 Common frpB iron-regulated outer membrane protein FrpB NMCC_0216 47 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 161870280 Common pepN membrane alanyl aminopeptidase NMCC_1321 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 161870971 Common tsf elongation factor TS NMCC_2066 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 161869281 Common glyQ glycyl-tRNA synthetase alpha chain NMCC_0286 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 161870964 Common - hypothetical protein NMCC_2059 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 161869682 Common scpB segregation and condensation protein B NMCC_0700 137 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 161869717 Pathogen - hypothetical protein NMCC_0737 1 None None None 161870418 Pathogen - hypothetical protein NMCC_1466 1 None None None 161871020 Common pncA pyrazinamidase/nicotinamidase PncA, putative NMCC_2116 58 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 161869050 Pathogen - lipoprotein NMCC_0033 1 None None None 161870081 Common - peptidyl-prolyl cis-trans isomerase NMCC_1119 110 None None None 161869715 Common - Mg-dependent DNase NMCC_0735 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 161869753 Common - hypothetical protein NMCC_0773 45 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 161869127 Common hemK HemK protein NMCC_0121 225 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 161869687 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase NMCC_0707 213 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 161869758 Common hisS1 histidyl-tRNA synthetase NMCC_0778 104 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 161869958 Common - hypothetical protein NMCC_0991 27 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 161870721 Common - hypothetical protein NMCC_1794 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 161869548 Common - IS1106A3 transposase NMCC_0563 17 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869936 Pathogen opcA outer membrane protein precursor NMCC_0968 1 None None None 161870530 Common parE topoisomerase IV subunit B NMCC_1595 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 161870287 Common - ATP-dependent RNA helicase, putative NMCC_1328 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 161870316 Common rep ATP-dependent DNA helicase NMCC_1358 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 161870376 Pathogen - hypothetical protein NMCC_1422 1 None None None 161869422 Common - IS1016 transposase NMCC_0430 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870901 Common rplR 50S ribosomal protein L18 NMCC_1991 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 161870201 Common uvrC excinuclease ABC subunit C NMCC_1241 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 161870806 Common nuoM NADH dehydrogenase chain M NMCC_1888 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 161870847 Common - integral membrane protein NMCC_1930 65 COG1971 COG1971, Predicted membrane protein Function unknown 161869885 Pathogen - integral membrane protein NMCC_0916 1 None None None 161870311 Common mutL DNA mismatch repair protein NMCC_1353 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 161869114 Common asd aspartate-semialdehyde dehydrogenase NMCC_0105 196 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 161869239 Common ausP autotransporter serine protease (AusP) NMCC_0244 75 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 161870239 Pathogen - hypothetical protein NMCC_1280 1 None None None 161870735 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase NMCC_1808 137 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 161869344 Common - hypothetical protein NMCC_0350 148 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 161870503 Pathogen - hypothetical protein NMCC_1560 1 None None None 161870522 Pathogen - integral membrane protein NMCC_1586 1 None None None 161870307 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit NMCC_1349 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 161870305 Common - hypothetical protein NMCC_1347 73 COG1556 COG1556, Uncharacterized conserved protein Function unknown 161869130 Common ppc phosphoenolpyruvate carboxylase NMCC_0124 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 161869650 Common holA DNA polymerase III, delta subunit NMCC_0667 101 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 161870359 Common - TonB-dependent receptor NMCC_1403 27 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 161869745 Common hemB delta-aminolevulinic acid dehydratase NMCC_0765 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 161869875 Common uvrA excinuclease ABC subunit A NMCC_0906 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 161869935 Common dedA putative DedA protein NMCC_0967 164 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 161869424 Common - oxidoreductase NMCC_0432 98 COG0431 COG0431, Predicted flavoprotein General function prediction only 161869659 Common - cytochrome, putative NMCC_0676 48 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 161869028 Common pgk phosphoglycerate kinase NMCC_0010 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 161870476 Common - transposase, IS30 family NMCC_1532 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161870291 Common - PspA-related protein NMCC_1333 22 None None None 161869679 Common - HPr kinase/phosphatase, putative NMCC_0697 70 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 161870853 Common - glutathione-regulated potassium-efflux system protein NMCC_1940 216 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 161870448 Common - hypothetical protein NMCC_1503 82 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 161869950 Common crcB integral membrane protein NMCC_0983 21 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 161869308 Common - preprotein translocase YidC subunit NMCC_0313 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 161870972 Common pyrH uridylate kinase NMCC_2067 236 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 161869866 Common gltA citrate synthase NMCC_0897 194 COG0372 GltA, Citrate synthase Energy production and conversion 161869040 Pathogen pilE fimbrial protein precursor (pilin) NMCC_0023 2 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161869701 Common purC phosphoribosylaminoimidazole-succinocarboxamidesynthase NMCC_0721 189 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 161870640 Common - putative translation factor NMCC_1710 229 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 161869120 Common thiG thiamine biosynthesis protein NMCC_0114 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 161869942 Common - hypothetical protein NMCC_0975 21 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 161869481 Common priA primosomal protein N' (replication factor Y) (superfamily II helicase) NMCC_0493 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 161870967 Common - hypothetical protein NMCC_2062 85 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 161870994 Pathogen - transferrin-binding protein-related protein NMCC_2089 2 None None None 161870687 Common rmpM outer membrane protein class 4 NMCC_1759 138 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 161870742 Common - hypothetical protein NMCC_1816 28 COG2707 COG2707, Predicted membrane protein Function unknown 161870823 Common nuoA NADH dehydrogenase I chain A NMCC_1905 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 161870212 Common proS prolyl-tRNA synthetase NMCC_1252 243 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870331 Common - transglycosylase NMCC_1375 61 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 161870674 Common xthA exodeoxyribonuclease III NMCC_1746 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 161870093 Common - two-component system, NarL family, nitrate/nitrite response regulator NarL NMCC_1131 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 161870527 Common trmA tRNA (uracil-5-)-methyltransferase NMCC_1592 163 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 161869675 Common bioD dethiobiotin synthetase NMCC_0693 156 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 161870882 Common ompH outer membrane protein OmpH, putative NMCC_1971 61 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 161870879 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase NMCC_1968 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 161869491 Pathogen - hypothetical protein NMCC_0504 1 None None None 161870649 Common ftsQ cell division protein NMCC_1719 82 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 161870116 Common - periplasmic protein NMCC_1155 6 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 161869528 Common - possible integral membrane protein NMCC_0542 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 161869170 Common - histidinol-phosphatase, putative NMCC_0166 127 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 161869382 Common ileS isoleucyl-tRNA synthetase NMCC_0389 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161869535 Common hisE phosphoribosyl-ATP cyclohydrolase NMCC_0549 180 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 161869488 Pathogen - hypothetical protein NMCC_0501 1 None None None 161870164 Common - C-5 cytosine-specific DNA-methylase NMCC_1203 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 161869839 Common pip proline iminopeptidase NMCC_0870 111 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 161869242 Common - hypothetical protein NMCC_0247 6 None None None 161871017 Common etfA electron transfer flavoprotein alpha-subunit NMCC_2113 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 161869731 Common recB exodeoxyribonuclease V beta subunit NMCC_0751 223 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 161869615 Pathogen - hypothetical protein NMCC_0631 1 None None None 161870889 Common valS valyl-tRNA synthetase NMCC_1978 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161870445 Common - hypothetical protein NMCC_1500 7 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 161870915 Common rplC 50S ribosomal protein L3 NMCC_2005 235 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 161870088 Pathogen - periplasmic protein NMCC_1126 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 161869275 Common atpF ATP synthase B chain NMCC_0280 77 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 161870127 Common aspA aspartate ammonia-lyase NMCC_1166 232 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 161870223 Common - aldehyde dehydrogenase NMCC_1264 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 161869726 Common - restriction endonuclease R.NgoVII NMCC_0746 4 None None None 161870338 Pathogen - hypothetical protein NMCC_1382 1 None None None 161870734 Common fabI enoyl-ACP reductase NMCC_1807 230 COG0623 FabI, Enoyl- acyl-carrier-protein 161870788 Common trpC indole-3-glycerol phosphate synthase NMCC_1870 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 161869049 Common glmS glucosamine--fructose-6-phosphate aminotransferase NMCC_0032 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 161869601 Common nspA outer membrane protein NMCC_0617 6 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 161870460 Common metZ O-succinylhomoserine sulfhydrolase NMCC_1515 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 161870485 Common - hypothetical protein NMCC_1541 160 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 161869795 Pathogen - hypothetical protein NMCC_0818 1 None None None 161869728 Common radA DNA repair protein NMCC_0748 206 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 161869997 Common - hypothetical protein NMCC_1030 14 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 161869765 Common pyrF orotidine 5'-phosphate decarboxylase NMCC_0785 160 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 161870578 Common - hypothetical protein NMCC_1644 74 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 161870014 Common - oxidoreductase, short chain dehydrogenase/reductase family NMCC_1047 187 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 161870352 Common - hypothetical protein NMCC_1396 216 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 161870942 Common rsmB 16S RNA methyltransferase NMCC_2036 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 161869895 Common purH bifunctional purine biosynthesis protein NMCC_0926 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 161870696 Pathogen - hypothetical protein NMCC_1768 1 None None None 161869033 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase NMCC_0016 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 161870196 Common rpsR 30S ribosomal protein S18 NMCC_1236 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 161870109 Common - lipoprotein NMCC_1148 3 None None None 161870952 Pathogen - lipoprotein NMCC_2046 1 None None None 161869513 Common - electron transfer flavoprotein-ubiquinone oxidoreductase NMCC_0527 112 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 161869079 Common - integral membrane protein NMCC_0068 42 COG1297 COG1297, Predicted membrane protein Function unknown 161869223 Pathogen - hypothetical protein NMCC_0227 1 None None None 161870815 Common nuoH NADH dehydrogenase I chain H NMCC_1897 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 161869351 Common hemL glutamate-1-semialdehyde 2,1-aminomutase NMCC_0357 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 161870003 Common - hypothetical protein NMCC_1036 22 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 161869228 Common - S-ribosylhomocysteine lyase NMCC_0232 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 161870660 Common murE UDP-N-acetylmuramyl-tripeptide synthetase NMCC_1730 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 161870347 Common recX regulatory protein RecX NMCC_1391 53 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 161869597 Common - hypothetical protein NMCC_0613 2 None None None 161870244 Common rbfA ribosomal-binding factor A NMCC_1285 168 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 161870317 Common dinP putative DNA-damage inducible protein P NMCC_1359 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 161870669 Common comM competence protein ComM NMCC_1741 192 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 161870375 Common fixS putative nitrogen fixation protein NMCC_1421 26 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 161869569 Common - hypothetical protein NMCC_0584 2 None None None 161869518 Common mntC putative periplasmic binding protein NMCC_0532 165 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 161870768 Common - CcsA-related protein NMCC_1849 109 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 161869255 Common cad cadmium resistance protein NMCC_0260 19 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 161869064 Common - putative endonuclease NMCC_0047 37 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 161870053 Common bfrA bacterioferritin A NMCC_1089 102 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 161870252 Common - NifS-like aminotranfserase NMCC_1293 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 161870934 Pathogen - integral membrane protein NMCC_2028 1 None None None 161869416 Common - cytochrome c-type biogenesis protein, putative NMCC_0424 62 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 161869172 Common ubiG 3-demethylubiquinone-9 3-methyltransferase NMCC_0169 176 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 161869073 Common dksA DnaK suppressor protein NMCC_0056 146 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 161870467 Common - IS1106A3 transposase NMCC_1522 39 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869825 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase NMCC_0854 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 161870453 Pathogen - hypothetical protein NMCC_1508 1 None None None 161869941 Pathogen - hypothetical protein NMCC_0974 1 None None None 161869844 Common - membrane protein NMCC_0875 29 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 161869213 Pathogen - hypothetical protein NMCC_0217 1 None None None 161870547 Common - IS1016 transposase NMCC_1612 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869436 Pathogen - hypothetical protein NMCC_0444 1 None None None 161870981 Pathogen - MafB-related protein NMCC_2076 1 COG5529 COG5529, Pyocin large subunit General function prediction only 161870044 Common - hypothetical protein NMCC_1077 220 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 161869461 Common - membrane protein NMCC_0473 54 COG1238 COG1238, Predicted membrane protein Function unknown 161870927 Common rplK 50S ribosomal protein L11 NMCC_2017 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 161869959 Common argB acetylglutamate kinase NMCC_0992 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 161870535 Common - Mg-dependent DNase NMCC_1600 233 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 161869137 Common metR LysR family transcriptional regulator, regulator for metE and metH NMCC_0131 188 COG0583 LysR, Transcriptional regulator Transcription 161869542 Common rpsO 30S ribosomal protein S15 NMCC_0556 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 161870622 Common - mutator MutT (7,8-dihydro-8-oxoguanine-triphosphatase) NMCC_1691 144 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 161869733 Common - amino acid permease substrate-binding protein NMCC_0753 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 161869540 Common secF protein-export membrane protein NMCC_0554 214 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 161870819 Common nuoE NADH dehydrogenase I chain E NMCC_1901 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 161870493 Common dsbB disulfide bond formation protein DsbB NMCC_1549 41 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 161869295 Common msbA putative ABC transporter ATP-binding protein NMCC_0300 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 161870072 Pathogen - membrane protein NMCC_1110 1 None None None 161870633 Pathogen - hypothetical protein NMCC_1703 1 None None None 161870281 Common - hypothetical protein NMCC_1322 30 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 161870290 Pathogen - hypothetical protein NMCC_1332 1 COG3792 COG3792, Uncharacterized protein conserved in bacteria Function unknown 161870907 Common rpmC 50S ribosomal protein L29 NMCC_1997 143 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 161870277 Common - IS1016C2 transposase NMCC_1318 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869233 Common lysA diaminopimelate decarboxylase NMCC_0237 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 161870204 Common uvrB excinuclease ABC subunit B NMCC_1244 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 161870936 Common topA DNA topoisomerase I NMCC_2030 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 161869649 Common - rare lipoprotein B, putative NMCC_0666 31 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 161869685 Common - hypothetical protein NMCC_0705 69 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 161870455 Common parC DNA topoisomerase IV subunit A NMCC_1510 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 161870519 Common - lipoprotein NMCC_1583 19 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 161870880 Common - integral membrane protein NMCC_1969 212 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 161870724 Common - cell-binding factor, putative NMCC_1797 47 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 161869917 Common - hypothetical protein NMCC_0949 8 None None None 161870770 Common dsbA2 thiol:disulphide interchange protein DsbA NMCC_1851 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 161869769 Common rfaD ADP-L-glycero-D-mannoheptose epimerase NMCC_0789 228 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 161869554 Common - hypothetical protein NMCC_0569 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 161869280 Common atpC ATP synthase epsilon chain NMCC_0285 172 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 161869219 Common app adhesion and penetration protein NMCC_0223 9 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161869161 Common - hypothetical protein NMCC_0156 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 161869767 Common nmgII DNA (cytosine-5-)-methyltransferase NMCC_0787 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 161869680 Common - hypothetical protein NMCC_0698 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 161869620 Common - hypothetical protein NMCC_0637 92 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 161869619 Common cnp1 periplasmic protein NMCC_0636 3 None None None 161869260 Common - hypothetical protein NMCC_0265 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 161870312 Common dnaZX DNA polymerase III tau and gamma subunit NMCC_1354 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 161870345 Pathogen - hypothetical protein NMCC_1389 1 None None None 161870531 Common - Probable (di)nucleoside polyphosphate hydrolase NMCC_1596 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 161869584 Pathogen - hypothetical protein NMCC_0600 1 None None None 161870466 Common - transposase, IS30 family NMCC_1521 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161869504 Common - membrane protein NMCC_0517 74 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 161869964 Common - transcriptional regulator, UmuD/LexA family NMCC_0997 49 COG2932 COG2932, Predicted transcriptional regulator Transcription 161869287 Common lgtE lacto-N-neotetraose biosynthesis glycosyl transferase LgtE NMCC_0292 18 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 161870152 Common - membrane-bound lytic murein transglycosylase B, putative NMCC_1191 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 161870540 Common aroX chorismate mutase-related protein NMCC_1605 66 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 161870071 Common hom homoserine dehydrogenase NMCC_1109 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 161869261 Common rpsU 30S ribosomal protein S21 NMCC_0266 97 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 161870171 Common - membrane bound murein transglycosylase NMCC_1210 135 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 161870270 Common mutY A/G-specific adenine glycosylase NMCC_1311 232 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 161870321 Common - putative DNA polymerase III subunit NMCC_1363 189 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 161869431 Common argC N-acetyl-gamma-glutamyl-phosphate reductase NMCC_0439 217 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 161869808 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NMCC_0833 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 161870078 Common lolC Lipoprotein releasing system transmembrane protein lolC NMCC_1116 216 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 161869195 Common - chloride channel protein-related protein NMCC_0198 140 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 161869644 Common rluD ribosomal large subunit pseudouridine synthase D NMCC_0661 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 161870587 Common - hypothetical protein NMCC_1654 2 None None None 161869454 Common - membrane protein NMCC_0465 23 COG3759 COG3759, Predicted membrane protein Function unknown 161870850 Common gyrB DNA gyrase subunit B NMCC_1933 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 161870977 Pathogen - putative MafB-like protein NMCC_2072 1 None None None 161869832 Common lst CMP-N-acetylneuraminate-beta-galactosamide- alpha- 2,3-sialyltransferase NMCC_0863 6 None None None 161869427 Common - putative ribonucleases G / cytoplasmic axial filament protein NMCC_0435 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 161870194 Pathogen - hypothetical protein NMCC_1234 1 None None None 161870606 Common - hypothetical periplasmic protein NMCC_1675 2 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 161869325 Common - hypothetical protein NMCC_0330 27 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 161870328 Common - hypothetical protein NMCC_1372 32 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 161869979 Pathogen - membrane protein NMCC_1012 1 None None None 161869055 Common phnA PhnA protein NMCC_0038 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 161869478 Common - HlyD family secretion protein NMCC_0490 172 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 161869091 Common ctrB capsule polysaccharide export inner-membrane protein NMCC_0080 39 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 161870510 Common - hypothetical protein NMCC_1573 117 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 161870695 Common mafB2 adhesin MafB2 NMCC_1767 3 None None None 161870744 Common rplU 50S ribosomal protein L21 NMCC_1818 213 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 161870392 Common - hypothetical protein NMCC_1439 6 None None None 161869691 Common - hypothetical protein NMCC_0711 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 161869372 Common farR regulator of the fatty acid efflux pump system NMCC_0379 30 COG1846 MarR, Transcriptional regulators Transcription 161869854 Common rpmE2 50S ribosomal protein L31 NMCC_0885 81 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 161870624 Common - Tou2 NMCC_1693 4 COG0730 COG0730, Predicted permeases General function prediction only 161869486 Pathogen - hypothetical protein NMCC_0499 1 None None None 161870011 Common - genome-derived Neisseria antigen 1162 NMCC_1044 22 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 161870955 Common - bacteriocin resistance protein, putative NMCC_2049 41 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 161869591 Pathogen - hypothetical protein NMCC_0607 1 None None None 161869970 Pathogen - hypothetical protein NMCC_1003 1 None None None 161869493 Common cysE serine acetyltransferase NMCC_0506 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 161870658 Common murF UDP-MurNAc-pentapeptide synthetase NMCC_1728 203 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 161870714 Common - hypothetical protein NMCC_1787 67 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 161870008 Common - hypothetical protein NMCC_1041 3 COG2336 MazE, Growth regulator Signal transduction mechanisms 161869634 Pathogen tpc tetrapac protein NMCC_0651 1 None None None 161869341 Common pyrE orotate phosphoribosyltransferase NMCC_0347 112 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 161869117 Common - transferase NMCC_0111 132 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 161869205 Common purL phophoribosylformylglycinamidine synthase NMCC_0209 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 161870261 Pathogen - hypothetical protein NMCC_1302 1 None None None 161870508 Common gmk guanylate kinase NMCC_1571 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 161869140 Common petB cytochrome B NMCC_0134 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 161869375 Common - integral membrane protein NMCC_0382 44 COG2510 COG2510, Predicted membrane protein Function unknown 161870614 Common - hypothetical protein NMCC_1683 100 COG3177 COG3177, Uncharacterized conserved protein Function unknown 161870894 Common rplQ 50S ribosomal protein L17 NMCC_1983 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 161869608 Common maeA malate oxidoreductase NMCC_0624 202 COG0281 SfcA, Malic enzyme Energy production and conversion 161870185 Common tig trigger factor NMCC_1225 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 161869395 Common avtA valine--pyruvate aminotransferase NMCC_0402 187 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 161870498 Common - hypothetical protein NMCC_1555 38 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 161870357 Common cstA carbon starvation protein A NMCC_1401 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 161869336 Common fetB2 ferric enterobactin transporter binding protein NMCC_0342 48 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 161869788 Common - membrane protein NMCC_0811 51 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 161870796 Common - RlpA-like protein precursor NMCC_1878 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 161870132 Common - hypothetical protein NMCC_1171 123 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 161870147 Pathogen - hypothetical protein NMCC_1186 1 None None None 161869781 Common - PhoH-related protein NMCC_0804 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 161870362 Common rph ribonuclease PH NMCC_1406 180 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 161870759 Common - hypothetical protein NMCC_1833 94 COG1981 COG1981, Predicted membrane protein Function unknown 161870647 Common ftsZ cell division protein NMCC_1717 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 161869661 Common tgt queuine tRNA-ribosyltransferase NMCC_0678 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 161870779 Common purB adenylosuccinate lyase NMCC_1861 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 161869129 Common slyX SlyX protein NMCC_0123 8 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 161869407 Common aroK shikimate kinase NMCC_0415 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 161869313 Common dnaN DNA polymerase III, beta subunit NMCC_0318 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 161869556 Common potD2 spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein NMCC_0571 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 161869777 Common recJ single-stranded-DNA-specific exonuclease NMCC_0800 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 161870120 Common leuC 3-isopropylmalate dehydratase large subunit NMCC_1159 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 161869629 Common trpF phosphoribosylanthranilate isomerase NMCC_0646 193 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 161869880 Pathogen - hypothetical protein NMCC_0911 1 None None None 161870763 Common aroG 3-deoxy-7-phosphoheptulonate synthase NMCC_1837 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 161870702 Pathogen - hypothetical protein NMCC_1774 1 None None None 161870557 Common - transcriptional regulator, GntR family NMCC_1623 131 COG2186 FadR, Transcriptional regulators Transcription 161870887 Common dadA D-amino acid dehydrogenase small subunit NMCC_1976 137 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 161870564 Pathogen - hypothetical protein NMCC_1630 1 None None None 161869153 Common pivNM-1B putative invertase/transposase NMCC_0148 90 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870987 Pathogen - hypothetical protein NMCC_2082 1 None None None 161869907 Pathogen - hypothetical protein NMCC_0939 1 None None None 161871024 Common mutS DNA mismatch repair protein NMCC_2120 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 161870591 Pathogen - integral membrane protein NMCC_1658 1 None None None 161869572 Common - HAM1 -like protein NMCC_0587 231 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 161870416 Common - hypothetical integral membrane protein NMCC_1464 48 COG2431 COG2431, Predicted membrane protein Function unknown 161869088 Common siaB polysialic acid capsule biosynthesis protein SiaB NMCC_0077 66 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 161870297 Pathogen - hypothetical protein NMCC_1339 1 None None None 161870672 Common putA proline dehydrogenase NMCC_1744 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 161870911 Common rpsS 30S ribosomal protein S19 NMCC_2001 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 161869821 Pathogen pilW type IV pilus assembly protein PilW NMCC_0850 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 161869283 Common glyS glycyl-tRNA synthetase beta subunit NMCC_0288 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 161870757 Common ompU putative outer membrane protein OmpU NMCC_1831 12 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 161869889 Common - modulator of drug activity B, putative NMCC_0920 45 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 161870978 Common - MafB-related protein NMCC_2073 3 None None None 161869342 Common - DNA polymerase, bacteriophage-type, putative NMCC_0348 20 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 161870766 Common - IS1016 transposase NMCC_1841 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869673 Pathogen - hypothetical protein NMCC_0691 1 None None None 161871031 Common - sodium-dependent inner membrane transport protein NMCC_0238 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 161869952 Common ftsK1 cell division protein FtsK NMCC_0985 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 161871019 Common rfaC lipopolysaccharide heptosyltransferase I NMCC_2115 60 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 161869244 Common - ABC transporter, ATP-binding protein NMCC_0249 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 161869995 Common - hypothetical protein NMCC_1028 28 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 161870821 Common nuoC NADH dehydrogenase I chain C NMCC_1903 167 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 161869185 Common - DNA transport competence protein NMCC_0188 128 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 161870601 Common - hypothetical protein NMCC_1669 14 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 161870922 Common rpoC DNA-directed RNA polymerase beta' chain NMCC_2012 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 161870067 Pathogen - periplasmic protein NMCC_1105 2 None None None 161869533 Common tatA sec-independent protein translocase component NMCC_0547 29 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 161869030 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase NMCC_0012 225 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 161869613 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase NMCC_0629 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 161869443 Common - hypothetical protein NMCC_0454 4 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 161870286 Common - tRNA-dihydrouridine synthase B NMCC_1327 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 161870598 Common - hypothetical protein NMCC_1666 2 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 161869110 Common - ATP-binding protein NMCC_0101 12 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 161869873 Common - hypothetical protein NMCC_0904 21 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869932 Common - hypothetical protein NMCC_0964 4 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 161870336 Common ppx exopolyphosphatase NMCC_1380 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 161869406 Common aroB 3-dehydroquinate synthase NMCC_0414 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 161870265 Common pgl 6-phosphogluconolactonase NMCC_1306 123 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 161870309 Common - methyltransferase NMCC_1351 88 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 161870384 Pathogen - proline-rich repeat protein NMCC_1430 1 None None None 161870656 Common mraY phopho-N-acetylmuramoyl-pentapeptide-transferase NMCC_1726 215 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 161870474 Common gpxA glutathione peroxidase NMCC_1530 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 161870319 Common - hypothetical protein NMCC_1361 88 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 161869031 Common - transmembrane transport protein NMCC_0014 98 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 161870143 Pathogen - hypothetical protein NMCC_1182 1 None None None 161870945 Common def polypeptide deformylase NMCC_2039 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 161870218 Common - myo-inositol-1(or 4)-monophosphatase NMCC_1259 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 161870350 Common nlpD lipoprotein NlpD, putative NMCC_1394 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 161869944 Common - hypothetical protein NMCC_0977 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 161870553 Pathogen - hypothetical protein NMCC_1619 1 None None None 161869903 Common - surface fibril protein NMCC_0935 36 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 161869183 Common kdtB lipopolysaccharide core biosynthesis protein NMCC_0180 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 161869432 Pathogen - hypothetical protein NMCC_0440 1 None None None 161869042 Pathogen - large pilS cassette NMCC_0025 2 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161869632 Pathogen - hypothetical protein NMCC_0649 1 None None None 161869677 Common ubiA 4-hydroxybenzoate octaprenyltransferase NMCC_0695 167 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 161870389 Common - methylated-DNA-protein-cysteinemethyltransferase NMCC_1436 200 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 161870925 Common rplJ 50S ribosomal protein L10 NMCC_2015 206 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 161870258 Pathogen - IS1016 family transposase, degenerate NMCC_1299 3 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869474 Common - hypothetical protein NMCC_0486 184 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 161870024 Common - ribosome-associated heat shock protein Hsp15 NMCC_1057 83 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 161869204 Common golB hydroxyacylglutathione hydrolase NMCC_0208 159 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 161869367 Common carA carbamoyl phosphate synthase small subunit NMCC_0373 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 161870781 Common - ribonuclease II-related protein NMCC_1863 147 COG0557 VacB, Exoribonuclease R Transcription 161870030 Pathogen - hypothetical protein NMCC_1063 1 None None None 161870561 Common mtrD drug efflux protein NMCC_1627 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 161869603 Common ligA DNA ligase NMCC_0619 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 161869358 Pathogen - hypothetical protein NMCC_0364 1 None None None 161869082 Common rfbB dTDP-D-glucose 4,6-dehydratase NMCC_0071 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 161869174 Common gntK thermoresistant gluconokinase NMCC_0171 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 161870042 Pathogen - hypothetical protein NMCC_1075 1 None None None 161869438 Common hecB hemolysin activation protein HecB, putative NMCC_0448 42 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 161870558 Common - L-lactate permease-related protein NMCC_1624 40 COG1620 LldP, L-lactate permease Energy production and conversion 161869062 Common - peptide methionine sulfoxide reductase NMCC_0045 207 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 161870548 Common fabF2 3-oxoacyl-(acyl-carrier-protein) synthase II NMCC_1613 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161869652 Common - membrane protein NMCC_0669 15 COG1714 COG1714, Predicted membrane protein/domain Function unknown 161869418 Common gcp O-sialoglycoprotein endopeptidase NMCC_0426 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 161870231 Common - pseudouridine synthase NMCC_1272 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 161870840 Common - hypothetical protein NMCC_1922 7 COG4304 COG4304, Uncharacterized protein conserved in bacteria Function unknown 161870378 Pathogen - hypothetical protein NMCC_1424 1 None None None 161870537 Common dedA putative DedA protein NMCC_1602 144 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 161870134 Pathogen - hypothetical protein NMCC_1173 1 None None None 161869823 Common - type IV pilus assembly protein NMCC_0852 57 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161870748 Common rpmG 50S ribosomal protein L33 NMCC_1822 140 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 161870988 Pathogen - hypothetical protein NMCC_2083 1 None None None 161869786 Common rdgC Recombination associated protein rdgC NMCC_0809 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 161869623 Common nusB N utilization substance protein B NMCC_0640 121 COG0781 NusB, Transcription termination factor Transcription 161870950 Common pyrB aspartate carbamoyltransferase catalytic chain NMCC_2044 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 161870202 Common - hypothetical protein NMCC_1242 89 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 161869210 Common - iron(III) ABC transporter, permease protein NMCC_0214 188 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 161869305 Common - hypothetical protein NMCC_0310 42 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 161870215 Common aceF dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex NMCC_1255 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 161869245 Common - putative ABC transport system permease protein NMCC_0250 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 161870106 Pathogen - hypothetical protein NMCC_1145 1 None None None 161870483 Pathogen - hypothetical protein NMCC_1539 1 None None None 161870761 Common - hypothetical protein NMCC_1835 47 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 161870012 Common - periplasmic protein NMCC_1045 7 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 161869756 Common - transposase NMCC_0776 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161870060 Common - lipoate-protein ligase B NMCC_1096 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 161869595 Pathogen - hypothetical protein NMCC_0611 1 None None None 161870828 Pathogen - hypothetical protein NMCC_1910 1 None None None 161869741 Common - hypothetical protein NMCC_0761 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 161870242 Common argD acetylornithine aminotransferase NMCC_1283 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 161870959 Common - hypothetical protein NMCC_2054 147 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 161869271 Pathogen - hypothetical protein NMCC_0276 1 None None None 161869511 Common nosF copper ABC transporter, ATP-binding protein NMCC_0525 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 161870055 Common - putative ATP-binding protein NMCC_1091 23 None None None 161869743 Common ftsJ cell division protein NMCC_0763 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 161869526 Common - two-component system sensor kinase NMCC_0540 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 161869467 Common - hypothetical protein NMCC_0479 202 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 161869806 Common - periplasmic protein NMCC_0831 100 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 161869524 Common rpsP 30S ribosomal protein S16 NMCC_0538 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 161869705 Common dapF diaminopimelate epimerase NMCC_0725 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 161870871 Pathogen - pilS cassette NMCC_1959 1 None None None 161870027 Common - RNA methyltransferase NMCC_1060 195 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 161869221 Common - hypothetical protein NMCC_0225 4 None None None 161869975 Pathogen - hypothetical protein NMCC_1008 1 None None None 161870620 Common - putative N6-adenine-specific DNA methylase NMCC_1689 130 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 161869077 Pathogen - hypothetical protein NMCC_0066 1 None None None 161870662 Common - cell division protein FtsL-related protein NMCC_1732 4 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 161870005 Common - hypothetical protein NMCC_1038 7 None None None 161869549 Pathogen - IS1016 family transposase, degenerate NMCC_0564 3 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 161869893 Common serB phosphoserine phosphatase NMCC_0924 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 161870855 Common aat leucyl/phenylalanyl-tRNA--protein transferase NMCC_1942 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 161869193 Common - hypothetical protein NMCC_0196 12 None None None 161870343 Common - hypothetical protein NMCC_1387 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 161869642 Common iga IgA-specific serine endopeptidase NMCC_0659 15 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161869815 Pathogen - hypothetical protein NMCC_0844 1 None None None 161870082 Common - ABC transporter, ATP-binding protein NMCC_1120 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 161870029 Pathogen - lipoprotein NMCC_1062 1 None None None 161869784 Common - deoxycytidine triphosphate deaminase, putative NMCC_0807 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 161870834 Common - hypothetical protein NMCC_1916 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 161870873 Common gidB glucose inhibited division protein B NMCC_1961 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 161869986 Pathogen - hypothetical protein NMCC_1019 1 None None None 161870876 Common frr ribosome recycling factor NMCC_1965 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 161870608 Common - integral membrane protein NMCC_1677 76 COG2928 COG2928, Uncharacterized conserved protein Function unknown 161869900 Pathogen - hypothetical protein NMCC_0932 2 None None None 161870076 Common recD exodeoxyribonuclease V, alpha subunit NMCC_1114 127 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 161869327 Pathogen secG protein-export integral membrane protein NMCC_0333 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 161870192 Common - hypothetical protein NMCC_1232 128 COG0730 COG0730, Predicted permeases General function prediction only 161869625 Common rnc ribonuclease III NMCC_0642 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 161870199 Common trxB thioredoxin reductase NMCC_1239 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 161869263 Pathogen - hypothetical protein NMCC_0268 1 None None None 161869450 Common - ribonuclease BN NMCC_0461 75 COG1295 Rbn, Predicted membrane protein Function unknown 161870730 Common - periplasmic hypothetical protein NMCC_1803 59 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 161869320 Common - DNA adenine methylase NMCC_0325 18 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 161869303 Common - hypothetical protein NMCC_0308 40 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 161870283 Common msbB acyl-transferase MsbB NMCC_1324 111 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 161870505 Common - DNA/pantothenate metabolism flavoprotein NMCC_1568 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 161870631 Common - hypothetical protein NMCC_1700 51 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 161869834 Common - oxidoreductase, short-chain dehydrogenase/reductase family NMCC_0865 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 161870693 Common - hypothetical protein NMCC_1765 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 161870717 Common - sugar isomerase, KpsF/GutQ family NMCC_1790 166 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 161870961 Common - hemolysin, putative NMCC_2056 53 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 161869993 Common - DNA-binding protein NMCC_1026 7 None None None 161870464 Common fumA fumarate hydratase NMCC_1519 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 161869273 Common atpB ATP synthase A chain NMCC_0278 190 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 161869639 Common ksgA dimethyladenosine transferase NMCC_0656 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 161870041 Common cysG siroheme synthase NMCC_1074 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 161869502 Common nqrA Na(+)-translocating NADH-ubiquinone reductase subunit A NMCC_0515 40 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 161870885 Common lpxA acyl-[acyl-carrier-protein]--UDP-N- acetylglucosam O-acyltransferase NMCC_1974 154 COG1043 LpxA, Acyl- acyl carrier protein 161870154 Common - very long chain acyl-CoA dehydrogenase-related protein NMCC_1193 17 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 161869909 Pathogen - hypothetical protein NMCC_0941 1 None None None 161869587 Pathogen - hypothetical protein NMCC_0603 1 None None None 161870512 Common - protease NMCC_1575 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 161870471 Common rnhA ribonuclease HI NMCC_1527 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 161869104 Common - lipoprotein NMCC_0094 2 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 161869334 Common - hypothetical protein NMCC_0340 34 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 161869711 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NMCC_0731 91 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 161869235 Common groES chaperonin 10 Kd subunit NMCC_0240 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 161869378 Pathogen - hypothetical protein NMCC_0385 1 None None None 161870786 Common - inner membrane virulence factor protein NMCC_1868 195 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 161870420 Common - hypothetical protein NMCC_1468 6 None None None 161870722 Common - D-tyrosyl-tRNA(Tyr) deacylase NMCC_1795 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 161869683 Common recN DNA repair protein NMCC_0701 211 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 161869026 Common ftsX ABC transporter integral membrane protein NMCC_0008 111 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 161869703 Common - hypothetical protein NMCC_0723 29 COG2836 COG2836, Uncharacterized conserved protein Function unknown 161870118 Common radC DNA repair protein NMCC_1157 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 161869202 Common - molecular chaperone Hsp33 NMCC_0205 121 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 161869217 Pathogen - hypothetical protein NMCC_0221 1 None None None 161869617 Common trpA tryptophan synthase alpha chain NMCC_0634 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 161870533 Common ldhA D-lactate dehydrogenase NMCC_1598 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 161869285 Common lgtB lacto-N-neotetraose biosynthesis glycosyl transferase LgtB NMCC_0290 12 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 161870098 Common ribA GTP cyclohydrolase II NMCC_1137 190 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 161870371 Common - thermonuclease family protein NMCC_1415 69 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 161870908 Common rplP 50S ribosomal protein L16 NMCC_1998 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 161869544 Common potC spermidine/putrescine ABC transporter, permease protein NMCC_0559 159 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 161869457 Pathogen - hypothetical protein NMCC_0469 1 None None None 161870233 Common xseA exonuclease VII large subunit NMCC_1274 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 161869915 Pathogen - hypothetical protein NMCC_0947 1 None None None 161869955 Common leuA 2-isopropylmalate synthase NMCC_0988 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 161870905 Common rplX 50S ribosomal protein L24 NMCC_1995 168 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 161870314 Common recA recombination protein RecA NMCC_1356 229 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 161870275 Common - IS1106A3 transposase NMCC_1316 18 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870939 Common ntrX nitrogen assimilation regulatory protein NtrX NMCC_2033 181 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 161870145 Common - periplasmic protein NMCC_1184 24 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 161869570 Common argH argininosuccinate lyase NMCC_0585 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 161869924 Pathogen - hypothetical protein NMCC_0956 1 None None None 161869663 Common infC translation initiation factor IF-3 NMCC_0681 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 161871001 Common prfB peptide chain release factor 2 NMCC_2097 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 161870410 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase NMCC_1458 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 161870566 Common recC exodeoxyribonuclease V gamma subunit NMCC_1632 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 161870368 Pathogen - hypothetical protein NMCC_1412 1 None None None 161869102 Common - hypothetical protein NMCC_0092 58 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 161869181 Common - hypothetical protein NMCC_0178 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 161870985 Pathogen mafB' MAFB alternative C-terminus NMCC_2080 1 None None None 161869400 Common - hypothetical protein NMCC_0407 3 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 161870645 Common prpB carboxyphosphonoenol pyruvate phosphonomutase NMCC_1715 135 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 161869864 Common sdhB succinate dehydrogenase iron-sulphur protein NMCC_0895 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 161870173 Common cmk cytidylate kinase NMCC_1213 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 161869930 Common - hypothetical protein NMCC_0962 9 COG0456 RimI, Acetyltransferases General function prediction only 161869779 Common pcnB poly(A) polymerase NMCC_0802 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 161869476 Common adhP alcohol dehydrogenase, propanol-preferring NMCC_0488 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 161869558 Common - hypothetical protein NMCC_0573 187 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 161869070 Common - hypothetical protein NMCC_0053 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 161869939 Pathogen - hypothetical protein NMCC_0972 1 None None None 161870704 Pathogen - hypothetical protein NMCC_1776 2 None None None 161870777 Common - hypothetical protein NMCC_1859 16 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 161869429 Common secB protein-export protein NMCC_0437 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 161869149 Pathogen - hypothetical protein NMCC_0143 1 None None None 161870555 Common gdhA glutamate dehydrogenase NMCC_1621 174 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 161870710 Common glnA glutamine synthetase NMCC_1782 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 161870427 Common acnB aconitate hydratase NMCC_1475 217 COG1049 AcnB, Aconitase B Energy production and conversion 161870593 Pathogen - hypothetical protein NMCC_1660 1 None None None 161869311 Common rpmH 50S ribosomal protein L34 NMCC_0316 3 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 161869356 Pathogen - hypothetical protein NMCC_0362 1 None None None 161870390 Common - putative AraC-family transcriptional regulator NMCC_1437 7 None None None 161869852 Common metX homoserine O-acetyltransferase NMCC_0883 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 161869388 Common - hypothetical protein NMCC_0395 13 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 161869043 Pathogen - pilS cassette NMCC_0026 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 161869579 Common - hypothetical protein NMCC_0595 4 None None None 161870861 Pathogen - hypothetical protein NMCC_1948 2 None None None 161870048 Common guaB inosine-5'-monophosphate dehydrogenase NMCC_1084 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 161870849 Common - integral membrane protein NMCC_1932 14 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 161869560 Common hisI phosphoribosyl-AMP cyclohydrolase NMCC_0575 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 161870334 Common opa95 opacity protein Opa95 NMCC_1378 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 161869981 Common - integral membrane protein NMCC_1014 8 None None None 161870401 Common - IS1106A3 transposase NMCC_1448 11 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161869972 Common - transposase for IS1655 NMCC_1005 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 161869227 Common polA DNA polymerase I NMCC_0231 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 161871013 Common - IS1106A3 transposase NMCC_2109 41 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 161870892 Common minD septum site-determining protein NMCC_1981 145 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 161869495 Common - periplasmic protein NMCC_0508 26 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 161870803 Common ispA geranyltranstransferase NMCC_1885 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 161869967 Common - phage transposase NMCC_1000 27 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 161869163 Common porB porin, major outer membrane protein P.I NMCC_0158 35 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 161869960 Pathogen - membrane protein NMCC_0993 1 None None None 161870612 Common tbpA transferrin-binding protein A NMCC_1681 71 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 161870431 Common ilvH acetolactate synthase isozyme III small subunit NMCC_1479 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 161870452 Common - hypothetical protein NMCC_1507 40 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 161870842 Common pyrD dihydroorotate dehydrogenase NMCC_1924 237 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 161870267 Common edd phosphogluconate dehydratase NMCC_1308 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 161869119 Pathogen - periplasmic protein NMCC_0113 1 None None None 161870260 Pathogen - hypothetical protein NMCC_1301 1 None None None 161870897 Common rpsM 30S ribosomal protein S13 NMCC_1987 238 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 161869142 Common - DNA recombination protein rmuC-like protein NMCC_0136 184 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 161870187 Common uraA uracil permease NMCC_1227 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 161869370 Common - ATP-binding protein involved in chromosome partitioning NMCC_0376 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 161870728 Common tspA Neisseria-specific antigen protein NMCC_1801 24 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 161869122 Common thiE thiamin-phosphate pyrophosphorylase NMCC_0116 198 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 161869846 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase NMCC_0877 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 161870488 Common - integral membrane protein NMCC_1544 17 COG0486 ThdF, Predicted GTPase General function prediction only 161869397 Common pglC pilin glycosylation protein NMCC_0404 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane