Rickettsia canadensis str. McKiel, complete genome NC_009879 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 157804011 Common - DNA-directed RNA polymerase subunit alpha A1E_04250 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 157803730 Common prfA peptide chain release factor 1 A1E_02750 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 157803551 Common - hypothetical protein A1E_01850 207 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 157803209 Common - ATP synthase subunit A A1E_00100 192 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 157803486 Common - pyruvate dehydrogenase subunit beta A1E_01525 18 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 157803494 Common - Cytochrome c1, heme protein precursor A1E_01565 77 COG2857 CYT1, Cytochrome c1 Energy production and conversion 157803946 Pathogen ppnK inorganic polyphosphate/ATP-NAD kinase A1E_03915 1 None None None 157803272 Common - 3-deoxy-D-manno-octulosonic-acid transferase A1E_00430 44 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 157803764 Common - hypothetical protein A1E_02940 1 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 157804060 Common - hypothetical protein A1E_04495 1 None None None 157803237 Pathogen - hypothetical protein A1E_00240 1 None None None 157803466 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase A1E_01425 164 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 157803538 Common - hypothetical protein A1E_01785 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157803642 Common - Transposase A1E_02305 2 None None None 157803506 Common - hypothetical protein A1E_01625 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 157803531 Common - 50S ribosomal protein L35 A1E_01750 94 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 157804187 Common - hypothetical protein A1E_05175 43 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 157803892 Common - hypothetical protein A1E_03625 1 None None None 157803859 Common - rare lipoprotein A precursor A1E_03440 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 157803830 Common - capM protein A1E_03295 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157803262 Common - hypothetical outer-membrane protein A1E_00380 30 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 157804170 Common - NADH dehydrogenase subunit G A1E_05090 21 COG3671 COG3671, Predicted membrane protein Function unknown 157803995 Common - hypothetical protein A1E_04170 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 157803715 Common - Tetratricopeptide repeat-containing protein A1E_02675 1 None None None 157804253 Common - NAD(P) transhydrogenase subunit alpha A1E_05515 99 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 157803202 Common - ComEC/Rec2-related protein A1E_00065 2 None None None 157803724 Common - hypothetical protein A1E_02720 1 None None None 157803850 Common - possible protease sohB A1E_03395 179 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157803274 Common - hypothetical protein A1E_00440 8 None None None 157804031 Common rpsS 30S ribosomal protein S19 A1E_04350 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 157803475 Common - hypothetical protein A1E_01470 1 None None None 157803610 Pathogen - hypothetical protein A1E_02145 1 None None None 157803738 Pathogen - hypothetical protein A1E_02805 1 None None None 157804167 Common - hypothetical protein A1E_05075 1 None None None 157803443 Common thrS threonyl-tRNA synthetase A1E_01310 1 None None None 157803513 Common - propionyl-CoA carboxylase beta chain precursor A1E_01660 214 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 157803862 Common - Multidrug resistance protein A1E_03455 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 157803291 Common - hypothetical protein A1E_00525 8 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 157803315 Common - succinate dehydrogenase A1E_00655 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 157803381 Common - DNA-binding protein HU A1E_00985 197 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 157804234 Pathogen - Predicted transcriptional regulator A1E_05410 1 None None None 157804150 Common - ampG protein A1E_04990 106 None None None 157803681 Common - hypothetical protein A1E_02500 1 None None None 157803350 Common - Ribosomal RNA large subunit methyltransferase J A1E_00830 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 157803659 Common - hypothetical protein A1E_02390 1 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 157804071 Common tdk thymidylate kinase A1E_04550 116 None None None 157804106 Common tgt queuine tRNA-ribosyltransferase A1E_04725 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 157803521 Pathogen - hypothetical protein A1E_01700 1 None None None 157803210 Common - hypothetical protein A1E_00105 2 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 157804241 Common - glycyl-tRNA synthetase alpha subunit A1E_05445 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 157803240 Common - putative inner membrane protein translocase component YidC A1E_00255 108 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 157803706 Common - Conjugal transfer protein TraA A1E_02630 2 None None None 157804001 Common - putative monovalent cation/H+ antiporter subunit D A1E_04200 203 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 157803297 Common - 50S ribosomal protein L19 A1E_00565 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 157803871 Common - GTP cyclohydrolase I A1E_03500 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 157803306 Common - hypothetical protein A1E_00610 16 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 157803406 Common rnhA ribonuclease H A1E_01125 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 157804147 Common - DNA polymerase III subunit alpha A1E_04975 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 157804000 Common - putative monovalent cation/H+ antiporter subunit C A1E_04195 88 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 157803583 Common - hypothetical protein A1E_02010 2 None None None 157804135 Pathogen - 3-oxoacyl-(acyl carrier protein) synthase II A1E_04915 1 None None None 157803649 Common - FeS cluster assembly scaffold IscU A1E_02340 146 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 157803247 Common - 2-dehydro-3-deoxyphosphooctonate aldolase A1E_00290 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 157804022 Common rpsN 30S ribosomal protein S14 A1E_04305 197 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 157803914 Common - hypothetical protein A1E_03745 1 None None None 157803601 Common - hypothetical protein A1E_02100 1 None None None 157803342 Common frr ribosome recycling factor A1E_00790 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 157803971 Pathogen - hypothetical protein A1E_04040 1 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 157803636 Common - primosome assembly protein PriA A1E_02275 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 157803905 Common - NADH dehydrogenase delta subunit A1E_03690 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 157803621 Common - hypothetical protein A1E_02200 144 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 157803335 Common - dihydrodipicolinate reductase A1E_00755 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 157803425 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase A1E_01220 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 157803469 Common - Cell division protein FtsA A1E_01440 177 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 157803458 Common - elongation factor P A1E_01385 6 None None None 157803667 Pathogen - hypothetical protein A1E_02430 1 None None None 157803364 Common - molecular chaperone DnaK A1E_00900 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 157803967 Common - hypothetical protein A1E_04020 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 157804112 Common - serine hydroxymethyltransferase A1E_04775 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 157803986 Pathogen - hypothetical protein A1E_04120 1 None None None 157803541 Pathogen - hypothetical protein A1E_01800 1 None None None 157804173 Common - F0F1 ATP synthase subunit beta A1E_05105 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 157804096 Common - Outer membrane protein B A1E_04675 70 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 157803613 Common - hypothetical protein A1E_02160 204 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 157804029 Common rpsC 30S ribosomal protein S3 A1E_04340 240 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 157804085 Common - hypothetical protein A1E_04620 1 None None None 157803460 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase A1E_01395 129 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 157803222 Common - clpB protein A1E_00165 220 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 157803752 Common - hypothetical protein A1E_02880 1 None None None 157803887 Common - Predicted permease A1E_03590 102 COG0679 COG0679, Predicted permeases General function prediction only 157804246 Common glyQ glycyl-tRNA synthetase subunit alpha A1E_05480 3 None None None 157803192 Common - O-antigen export system ATP-binding protein RfbE A1E_00015 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 157804104 Common - DNA ligase A1E_04715 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 157803845 Common - hypothetical protein A1E_03370 49 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 157803422 Common - methionyl-tRNA formyltransferase A1E_01205 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 157803793 Common - Predicted permease A1E_03110 16 COG0679 COG0679, Predicted permeases General function prediction only 157803229 Common - tRNA(Ile)-lysidine synthetase TilS A1E_00200 208 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 157803304 Common - Holliday junction resolvase A1E_00600 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 157803567 Common - protein export protein SecD A1E_01930 220 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 157803591 Common - Methylated-DNA--protein-cysteine methyltransferase A1E_02050 206 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 157803340 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A A1E_00780 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 157804055 Common - exodeoxyribonuclease VII large subunit A1E_04470 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 157803633 Common - hypothetical protein A1E_02260 1 None None None 157804212 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase A1E_05300 207 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 157804083 Common - Trans-regulatory protein ExsB A1E_04610 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 157803395 Common - excinuclease ABC subunit B A1E_01055 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 157804073 Common ubiA prenyltransferase A1E_04560 2 None None None 157803922 Common - hypothetical protein A1E_03785 47 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157803397 Pathogen - hypothetical protein A1E_01080 1 None None None 157803931 Common - Holliday junction resolvase-like protein A1E_03830 185 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 157803976 Common - hypothetical protein A1E_04065 1 None None None 157803751 Pathogen - hypothetical protein A1E_02875 1 None None None 157803524 Pathogen - hypothetical protein A1E_01715 1 None None None 157803864 Pathogen - hypothetical protein A1E_03465 1 None None None 157803809 Pathogen - hypothetical protein A1E_03190 1 None None None 157803504 Common groES co-chaperonin GroES A1E_01615 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 157803820 Common - ribonuclease D A1E_03245 80 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 157803412 Pathogen - hypothetical protein A1E_01155 1 None None None 157803880 Pathogen - hypothetical protein A1E_03555 1 None None None 157804034 Common rplD 50S ribosomal protein L4 A1E_04365 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 157803942 Common - frataxin-like protein A1E_03895 17 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 157804197 Pathogen - hypothetical protein A1E_05225 1 None None None 157804043 Pathogen - hypothetical protein A1E_04410 1 None None None 157803657 Common - ampG protein A1E_02380 102 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 157803284 Pathogen - Acetylglutamate kinase A1E_00490 1 None None None 157804276 Common - Oxidoreductase A1E_05645 141 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 157803282 Common - 50S ribosomal protein L31 A1E_00480 8 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 157803323 Common rplK 50S ribosomal protein L11 A1E_00695 239 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 157803359 Common - hypothetical protein A1E_00875 29 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 157803758 Common - pyruvate phosphate dikinase A1E_02910 7 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 157803989 Pathogen - hypothetical protein A1E_04135 1 None None None 157803695 Common rpsA 30S ribosomal protein S1 A1E_02575 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 157803408 Common - ABC transporter substrate binding protein A1E_01135 74 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 157803673 Common - alkaline phosphatase synthesis sensor protein phor (phor) A1E_02460 1 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157804224 Common uvrA excinuclease ABC subunit A A1E_05360 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 157803743 Pathogen - hypothetical protein A1E_02835 1 COG4285 COG4285, Uncharacterized conserved protein Function unknown 157803725 Common - hypothetical protein A1E_02725 1 None None None 157803511 Common - acylglycerophosphoethanolamine acyltransferase A1E_01650 226 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157804278 Common mutL DNA mismatch repair protein A1E_05655 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157803615 Pathogen - hypothetical protein A1E_02170 1 None None None 157803279 Common - Ribonucleotide ABC transporter ATP-binding protein A1E_00465 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 157803875 Pathogen - hypothetical protein A1E_03520 1 None None None 157804126 Common - hypothetical protein A1E_04845 26 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 157803709 Pathogen - hypothetical protein A1E_02645 1 None None None 157803245 Common - ABC transporter ATP-binding protein A1E_00280 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 157803935 Common - thioredoxin peroxidase 1 A1E_03850 223 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 157803852 Common - Protocatechuate-3,4-dioxygenase, beta subunit A1E_03405 37 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 157803789 Pathogen - hypothetical protein A1E_03090 1 None None None 157803473 Pathogen ddl D-alanine--D-alanine ligase A1E_01460 1 None None None 157803992 Common - hypothetical protein A1E_04155 118 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 157803439 Common - transposase IS200-family protein A1E_01290 10 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157803909 Common - 3-methyladenine DNA glycosylase A1E_03710 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 157803736 Pathogen - hypothetical protein A1E_02780 1 None None None 157803623 Common - translation initiation factor IF-2 A1E_02210 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 157803260 Pathogen - hypothetical protein A1E_00360 1 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 157804179 Common - Penicillin-binding protein 1A family A1E_05135 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 157804255 Common greA transcription elongation factor GreA A1E_05540 7 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 157803919 Common - Predicted hydrolase or acyltransferase A1E_03770 64 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 157803518 Common - isoleucyl-tRNA synthetase A1E_01685 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803900 Common - hypothetical protein A1E_03665 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 157803533 Common - 50S ribosomal protein L25/general stress protein Ctc A1E_01760 192 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 157803815 Common - petR protein A1E_03220 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157803239 Common - ADP,ATP carrier protein A1E_00250 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 157804263 Common - DNA polymerase III subunit chi A1E_05580 19 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 157803581 Pathogen - Ankyrin repeat A1E_02000 1 None None None 157803366 Common - hypothetical protein A1E_00910 16 COG4572 ChaB, Putative cation transport regulator General function prediction only 157803370 Common kgd alpha-ketoglutarate decarboxylase A1E_00930 150 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 157803200 Common - zinc/manganese ABC transporter substrate binding protein A1E_00055 34 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 157803588 Common - excinuclease ABC subunit C A1E_02035 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 157804018 Common rpsE 30S ribosomal protein S5 A1E_04285 243 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 157803832 Common - hypothetical protein A1E_03305 1 None None None 157803644 Pathogen - hypothetical protein A1E_02315 1 None None None 157804161 Common - NADH dehydrogenase subunit L A1E_05045 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 157803771 Pathogen - hypothetical protein A1E_02975 1 None None None 157803675 Common - Glycine cleavage T-protein A1E_02470 82 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 157803767 Common - tRNA delta(2)-isopentenylpyrophosphate transferase A1E_02955 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 157803234 Common - putative carbamate kinase A1E_00225 60 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 157803491 Common - hypothetical protein A1E_01550 1 None None None 157803484 Pathogen - hypothetical protein A1E_01515 1 None None None 157803325 Common rplJ 50S ribosomal protein L10 A1E_00705 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 157804152 Common - seryl-tRNA synthetase A1E_05000 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803349 Common - transcription antitermination protein NusB A1E_00825 75 COG0781 NusB, Transcription termination factor Transcription 157803777 Common - hypothetical protein A1E_03005 4 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 157804209 Pathogen xerC site-specific tyrosine recombinase XerC A1E_05285 1 None None None 157803207 Common - F0F1 ATP synthase subunit B' A1E_00090 29 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 157803984 Common - hypothetical protein A1E_04105 1 None None None 157803548 Common - hypothetical protein A1E_01835 17 COG2938 COG2938, Uncharacterized conserved protein Function unknown 157803231 Common - succinate dehydrogenase catalytic subunit A1E_00210 191 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 157804078 Common - Alpha-(1,3)-fucosyltransferase A1E_04585 1 None None None 157803907 Common - NADH dehydrogenase I chain E A1E_03700 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 157803269 Common rpsB 30S ribosomal protein S2 A1E_00415 231 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 157803333 Common - aspartyl-tRNA synthetase A1E_00745 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803483 Common - GTP-binding protein A1E_01510 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 157803558 Common - hypothetical protein A1E_01885 1 None None None 157804007 Common - Protease II A1E_04230 106 COG1770 PtrB, Protease II Amino acid transport and metabolism 157803873 Pathogen - hypothetical protein A1E_03510 1 None None None 157803803 Common - Predicted membrane protein A1E_03160 8 COG1238 COG1238, Predicted membrane protein Function unknown 157803576 Common - DNA-directed RNA polymerase omega subunit A1E_01975 59 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 157803212 Common - hypothetical protein A1E_00115 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 157803957 Common - hypothetical protein A1E_03970 129 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 157803492 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit A1E_01555 104 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 157804185 Common - hypothetical protein A1E_05165 1 None None None 157803503 Common rph ribonuclease PH A1E_01610 25 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 157804038 Common - elongation factor Tu A1E_04385 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 157803190 Common - hypothetical protein A1E_00005 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 157804200 Common - Maf-like protein A1E_05240 192 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 157803308 Common - protease activity modulator HflK A1E_00620 158 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 157803631 Common - predicted repair protein A1E_02250 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 157803543 Pathogen - hypothetical protein A1E_01810 1 None None None 157803843 Common - Cytochrome c oxidase polypeptide I A1E_03360 171 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 157803355 Common - hypothetical protein A1E_00855 8 None None None 157803444 Common - DNA topoisomerase IV subunit B A1E_01315 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 157803196 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase A1E_00035 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 157803383 Common - hypothetical protein A1E_00995 5 COG2155 COG2155, Uncharacterized conserved protein Function unknown 157803854 Pathogen - hypothetical protein A1E_03415 1 None None None 157803399 Pathogen - hypothetical protein A1E_01090 1 None None None 157804066 Common - hypothetical protein A1E_04525 1 None None None 157804057 Common xseA exodeoxyribonuclease VII large subunit A1E_04480 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 157803920 Common - hypothetical protein A1E_03775 2 None None None 157803769 Common nrdF ribonucleotide-diphosphate reductase subunit beta A1E_02965 155 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 157803949 Common - hypothetical protein A1E_03930 179 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 157803708 Common - Conjugal transfer protein TraA A1E_02640 1 None None None 157803939 Pathogen - hypothetical protein A1E_03880 1 None None None 157803933 Pathogen - hypothetical protein A1E_03840 1 None None None 157803754 Common - Glutamine synthetase A1E_02890 209 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 157803650 Common - Iron-sulfur cluster assembly accessory protein A1E_02345 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 157804222 Common - hypothetical protein A1E_05350 78 COG1881 COG1881, Phospholipid-binding protein General function prediction only 157803390 Common - hypothetical protein A1E_01030 1 None None None 157803451 Common - 30S ribosomal protein S9 A1E_01350 217 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 157803620 Common - tyrosyl-tRNA synthetase A1E_02195 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 157803224 Common - sialoglycoprotease A1E_00175 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 157803790 Pathogen - hypothetical protein A1E_03095 1 None None None 157803606 Pathogen - hypothetical protein A1E_02125 1 None None None 157803377 Common - coproporphyrinogen III oxidase A1E_00965 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 157803603 Common - nitrogen assimilation regulatory protein NtrX A1E_02110 213 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 157804133 Common - 3-oxoacyl-(acyl carrier protein) synthase A1E_04880 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157803481 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase A1E_01500 163 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 157803417 Pathogen - hypothetical protein A1E_01180 1 None None None 157803974 Common - hypothetical protein A1E_04055 153 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 157804087 Pathogen - hypothetical protein A1E_04630 1 None None None 157803940 Common - hypothetical protein A1E_03885 1 None None None 157804248 Common truA tRNA pseudouridine synthase A A1E_05490 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 157804194 Pathogen - hypothetical protein A1E_05210 1 None None None 157803357 Common - cytochrome c oxidase subunit III A1E_00865 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 157804028 Common rplP 50S ribosomal protein L16 A1E_04335 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 157803286 Common - Type IV secretion/conjugal transfer ATPase, VirB4 family protein A1E_00500 66 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 157803655 Common - ADP,ATP carrier protein A1E_02370 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 157803749 Common - hypothetical protein A1E_02865 2 None None None 157803912 Common - 16S rRNA-processing protein A1E_03725 121 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 157803969 Pathogen - hypothetical protein A1E_04030 1 None None None 157804210 Common - methionine aminopeptidase A1E_05290 243 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 157803258 Common - hypothetical protein A1E_00345 83 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 157803727 Common - transcription termination factor Rho A1E_02735 206 COG1158 Rho, Transcription termination factor Transcription 157803889 Common - hypothetical protein A1E_03600 8 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 157803817 Common - undecaprenyl pyrophosphate synthetase A1E_03230 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 157803800 Common - hypothetical protein A1E_03145 1 None None None 157804091 Common - hypothetical protein A1E_04650 2 COG5160 ULP1, Protease, Ulp1 family Posttranslational modification, protein turnover, chaperones 157804232 Common obgE GTPase ObgE A1E_05400 249 COG0536 Obg, Predicted GTPase General function prediction only 157804094 Pathogen - hypothetical protein A1E_04665 1 None None None 157804202 Common - tyrosine recombinase A1E_05250 223 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157803313 Common - hypothetical protein A1E_00645 1 None None None 157804140 Common - hypothetical protein A1E_04940 52 COG0795 COG0795, Predicted permeases General function prediction only 157803740 Common - folylpolyglutamate synthase A1E_02820 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 157803822 Common - hypothetical protein A1E_03255 17 None None None 157803760 Common rpsO 30S ribosomal protein S15 A1E_02920 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 157804046 Common - ATP-dependent RNA helicase RhlE A1E_04425 243 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 157803593 Common - hypothetical protein A1E_02060 122 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 157804036 Common rpsJ 30S ribosomal protein S10 A1E_04375 230 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 157804041 Pathogen - hypothetical protein A1E_04400 1 None None None 157803565 Common - Cytochrome c-type biogenesis protein CcmE A1E_01920 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 157804163 Common - heme exporter protein A A1E_05055 235 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 157803787 Common - transposase IS200-family protein A1E_03080 10 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157803586 Pathogen - hypothetical protein A1E_02025 1 None None None 157803414 Pathogen - hypothetical protein A1E_01165 1 None None None 157804190 Common - hypothetical protein A1E_05190 48 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 157803902 Common - NADH dehydrogenase beta subunit A1E_03675 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 157803214 Common - recombination protein F A1E_00125 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 157804006 Common - NADH dehydrogenase subunit N A1E_04225 159 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 157803574 Common - DNA gyrase subunit B A1E_01965 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 157803805 Common - hypothetical protein A1E_03170 4 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 157803813 Common - dihydrodipicolinate synthase A1E_03210 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 157803837 Common - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase A1E_03330 212 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 157803824 Common - phenylalanyl-tRNA synthetase beta subunit A1E_03265 243 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 157803958 Common - hypothetical protein A1E_03975 122 None None None 157803426 Common - Multidrug resistance ABC transporter ATP-binding protein A1E_01225 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 157804265 Pathogen - hypothetical protein A1E_05590 1 None None None 157803687 Pathogen - hypothetical protein A1E_02535 1 None None None 157803501 Common - hypothetical protein A1E_01600 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 157804223 Common - methionine aminopeptidase A1E_05355 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 157804258 Common - hypothetical protein A1E_05555 40 COG3577 COG3577, Predicted aspartyl protease General function prediction only 157803361 Common - hypothetical protein A1E_00885 1 None None None 157804272 Common rpmG 50S ribosomal protein L33 A1E_05625 124 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 157803339 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B A1E_00775 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 157803910 Common - exodeoxyribonuclease VII small subunit A1E_03715 97 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 157803388 Common - hypothetical protein A1E_01020 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 157804193 Pathogen - hypothetical protein A1E_05205 1 None None None 157803267 Common secG preprotein translocase subunit SecG A1E_00405 5 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 157803402 Common - DNA polymerase III subunit epsilon A1E_01105 191 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 157803243 Common - soj protein A1E_00270 223 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 157803409 Pathogen - hypothetical protein A1E_01140 1 None None None 157804280 Common - coproporphyrinogen III oxidase A1E_05665 96 COG1981 COG1981, Predicted membrane protein Function unknown 157803293 Pathogen - hypothetical protein A1E_00545 1 None None None 157803702 Common - hypothetical protein A1E_02610 10 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 157803347 Common - Outer membrane protein omp1 A1E_00815 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 157803587 Common - Sodium/pantothenate symporter A1E_02030 107 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 157803718 Common - hypothetical protein A1E_02690 1 None None None 157803963 Pathogen - hypothetical protein A1E_04000 1 None None None 157803462 Common - hypothetical protein A1E_01405 1 None None None 157803419 Common - hypothetical protein A1E_01190 1 None None None 157804124 Common - Proline/betaine transporter A1E_04835 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157803499 Common - hypothetical protein A1E_01590 49 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 157803225 Common - O-sialoglycoprotein endopeptidase A1E_00180 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 157803663 Pathogen - hypothetical protein A1E_02410 1 None None None 157803478 Common - ribosomal large subunit pseudouridine synthase C A1E_01485 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 157803877 Common - malate dehydrogenase A1E_03540 194 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 157803236 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase A1E_00235 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 157803368 Common - DNA repair protein RecN A1E_00920 229 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 157803572 Pathogen - hypothetical protein A1E_01955 1 None None None 157803278 Common - ABC transporter permease protein A1E_00460 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 157803698 Common - hypothetical protein A1E_02590 1 None None None 157804251 Common dnaG DNA primase A1E_05505 12 COG0170 SEC59, Dolichol kinase Lipid metabolism 157803896 Pathogen - hypothetical protein A1E_03645 1 None None None 157803786 Pathogen - hypothetical protein A1E_03065 1 None None None 157803434 Common - threonyl-tRNA synthetase A1E_01265 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803734 Pathogen - hypothetical protein A1E_02770 1 None None None 157803516 Common - acylglycerophosphoethanolamine acyltransferase A1E_01675 240 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 157803563 Pathogen - hypothetical protein A1E_01910 1 None None None 157804182 Pathogen - hypothetical protein A1E_05150 1 None None None 157803437 Common - hypothetical protein A1E_01280 2 None None None 157803205 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase A1E_00080 1 None None None 157803254 Common - DNA topoisomerase IV subunit A A1E_00325 6 None None None 157804238 Common - tRNA (guanine-N(7)-)-methyltransferase A1E_05430 226 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 157804062 Common engA GTP-binding protein EngA A1E_04505 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 157803528 Common rnpA ribonuclease P A1E_01735 5 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 157804047 Common - cold shock-like protein A1E_04430 172 COG1278 CspC, Cold shock proteins Transcription 157803311 Common - hypothetical protein A1E_00635 109 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 157803643 Common - hypothetical protein A1E_02310 4 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157803488 Common - putative monovalent cation/H+ antiporter subunit G A1E_01535 1 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 157803392 Common hscA chaperone protein HscA A1E_01040 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 157803711 Common - Conjugal transfer protein TraA A1E_02655 6 None None None 157803379 Common - coproporphyrinogen III oxidase A1E_00975 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 157803954 Common - hypothetical protein A1E_03955 162 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 157804080 Common valS valyl-tRNA synthetase A1E_04595 1 None None None 157803860 Common - Penicillin-binding protein DacF precursor A1E_03445 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 157803472 Common - cytochrome c A1E_01455 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 157803203 Pathogen - hypothetical protein A1E_00070 1 None None None 157803968 Common - hypothetical protein A1E_04025 2 None None None 157804099 Common - lipid A biosynthesis lauroyl acyltransferase A1E_04690 113 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 157803799 Common - hypothetical protein A1E_03140 1 None None None 157804139 Common - Rod shape-determining protein MreB A1E_04935 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 157803869 Common - hypothetical protein A1E_03490 7 COG3177 COG3177, Uncharacterized conserved protein Function unknown 157803288 Common - TrbL/VirB6 plasmid Conjugative transfer protein A1E_00510 7 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 157803519 Common ileS isoleucyl-tRNA synthetase A1E_01690 22 COG5590 COG5590, Uncharacterized conserved protein Function unknown 157803677 Common - Ribonuclease D A1E_02480 114 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 157803327 Common rpoB DNA-directed RNA polymerase subunit beta A1E_00715 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 157803747 Pathogen - hypothetical protein A1E_02855 1 None None None 157803372 Common - hypothetical protein A1E_00940 91 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 157803779 Common - ribonucleotide-diphosphate reductase subunit alpha A1E_03015 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 157803721 Pathogen - hypothetical protein A1E_02705 1 None None None 157803691 Common - isopentenyl pyrophosphate isomerase A1E_02555 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 157804026 Common rpsQ 30S ribosomal protein S17 A1E_04325 230 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 157803404 Common - hypothetical protein A1E_01115 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 157803625 Common infB translation initiation factor IF-2 A1E_02220 152 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 157803882 Common - hypothetical protein A1E_03565 1 None None None 157804116 Common - hypothetical protein A1E_04795 210 COG0313 COG0313, Predicted methyltransferases General function prediction only 157804208 Pathogen - hypothetical protein A1E_05280 1 None None None 157803555 Common - Succinyl-CoA:3-ketoacid-coenzyme A transferase A1E_01870 6 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 157804228 Common - hypothetical protein A1E_05380 9 COG1872 COG1872, Uncharacterized conserved protein Function unknown 157803453 Common rpsI 30S ribosomal protein S9 A1E_01360 98 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 157803608 Pathogen - hypothetical protein A1E_02135 1 None None None 157803701 Common - hypothetical protein A1E_02605 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 157803982 Common - hypothetical protein A1E_04095 1 None None None 157804165 Common - NADH dehydrogenase subunit M A1E_05065 1 None None None 157803927 Common - UDP-N-acetylglucosamine 2-epimerase A1E_03810 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 157803785 Pathogen - hypothetical protein A1E_03045 1 None None None 157803545 Pathogen - hypothetical protein A1E_01820 1 None None None 157804157 Pathogen - hypothetical protein A1E_05025 1 None None None 157803353 Common nusB transcription antitermination protein NusB A1E_00845 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 157803617 Pathogen - hypothetical protein A1E_02180 1 None None None 157804050 Pathogen - hypothetical protein A1E_04445 1 None None None 157803429 Common - Cytochrome d ubiquinol oxidase subunit II A1E_01240 146 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 157804219 Common - cytosine deaminase A1E_05335 207 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 157803630 Common - Uncharacterized low-complexity protein A1E_02245 68 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 157803637 Pathogen - hypothetical protein A1E_02280 1 None None None 157803849 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase A1E_03390 182 COG0756 Dut, dUTPase Nucleotide transport and metabolism 157803374 Common - proton/sodium-glutamate symport protein A1E_00950 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 157804059 Common - hypothetical protein A1E_04490 1 None None None 157803595 Common - Cell division protein FtsL A1E_02070 1 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 157804100 Common - tetraacyldisaccharide 4'-kinase A1E_04695 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 157804068 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase A1E_04535 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 157803990 Pathogen - hypothetical protein A1E_04140 1 None None None 157803720 Common - hypothetical protein A1E_02700 2 None None None 157803773 Common - Thioredoxin reductase A1E_02985 234 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 157803679 Common - dihydrolipoamide dehydrogenase A1E_02490 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 157803345 Common - Multidrug resistance protein B A1E_00805 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157803999 Common - hypothetical protein A1E_04190 55 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 157804204 Common - UbiD family decarboxylase A1E_05260 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 157804149 Common - hypothetical protein A1E_04985 14 COG3164 COG3164, Predicted membrane protein Function unknown 157804108 Common - ADP,ATP carrier protein A1E_04755 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 157803337 Common - dihydrodipicolinate reductase A1E_00765 141 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157803972 Common - hypothetical protein A1E_04045 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 157803322 Common nusG transcription antitermination protein NusG A1E_00690 216 COG0250 NusG, Transcription antiterminator Transcription 157804199 Common infA translation initiation factor IF-1 A1E_05235 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 157803329 Common - DNA-directed RNA polymerase subunit beta' A1E_00725 1 None None None 157804129 Pathogen trmE tRNA modification GTPase TrmE A1E_04860 1 None None None 157804023 Common rplE 50S ribosomal protein L5 A1E_04310 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 157803527 Common rpsU 30S ribosomal protein S21 A1E_01730 1 None None None 157804074 Common - valyl-tRNA synthetase A1E_04565 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157804236 Common - N-terminus of bacteriophage-type DNA polymerase A1E_05420 151 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 157803303 Common era GTP-binding protein Era A1E_00595 229 COG1159 Era, GTPase General function prediction only 157803839 Common - signal peptidase II A1E_03340 187 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157803330 Common - leucyl aminopeptidase A1E_00730 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 157803216 Pathogen - hypothetical protein A1E_00135 1 None None None 157803923 Common - minor teichoic acids biosynthesis protein ggab (ggab) A1E_03790 197 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 157804089 Common - hypothetical protein A1E_04640 202 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 157804142 Common - 3-oxoacyl-(acyl carrier protein) synthase III A1E_04950 216 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 157803448 Common - hypothetical protein A1E_01335 2 None None None 157803886 Common - phosphate acetyltransferase A1E_03585 208 COG0281 SfcA, Malic enzyme Energy production and conversion 157803826 Common - MiaB-like tRNA modifying enzyme A1E_03275 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 157804003 Common - NADH dehydrogenase subunit N A1E_04210 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 157804105 Common ligA NAD-dependent DNA ligase LigA A1E_04720 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 157803363 Common holA DNA polymerase III subunit delta A1E_00895 194 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 157804221 Common - 17 kDa surface antigen precursor A1E_05345 26 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 157804159 Common - NADH dehydrogenase subunit J A1E_05035 156 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 157803732 Common - translation initiation factor IF-3 A1E_02760 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 157803612 Common - Proline/betaine transporter A1E_02155 114 None None None 157803894 Common - enoyl-(acyl carrier protein) reductase A1E_03635 229 COG0623 FabI, Enoyl- acyl-carrier-protein 157803585 Common - Type I restriction-modification system, M subunit A1E_02020 8 None None None 157804260 Common - hypothetical protein A1E_05565 89 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 157803276 Common - aspartate aminotransferase A1E_00450 51 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 157804274 Common - hypothetical protein A1E_05635 1 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 157803432 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase A1E_01255 146 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 157803570 Pathogen - hypothetical protein A1E_01945 1 None None None 157803647 Common - hypothetical protein A1E_02330 235 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 157803561 Common - hypothetical protein A1E_01900 3 None None None 157803295 Pathogen - hypothetical protein A1E_00555 1 None None None 157803930 Pathogen - hypothetical protein A1E_03825 1 None None None 157803653 Common - Octaprenyl-diphosphate synthase A1E_02360 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 157803514 Pathogen - hypothetical protein A1E_01665 1 None None None 157803683 Pathogen - dihydrolipoamide dehydrogenase A1E_02510 1 None None None 157803256 Common - export protein SecB A1E_00335 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 157803627 Common recO DNA repair protein RecO A1E_02230 2 None None None 157803818 Common - Phosphatidate cytidylyltransferase A1E_03235 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 157803553 Common - Actin polymerization protein RickA A1E_01860 14 COG5373 COG5373, Predicted membrane protein Function unknown 157803456 Common - elongation factor P A1E_01375 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 157803665 Common - scaffold protein A1E_02420 165 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 157803950 Common - hypothetical protein A1E_03935 2 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 157804175 Common - F0F1 ATP synthase subunit alpha A1E_05115 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 157803704 Common - Conjugal transfer protein TraD A1E_02620 4 None None None 157803441 Common - outer membrane protein tolC precursor A1E_01300 112 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157804180 Common - hypothetical protein A1E_05140 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 157804015 Common secY preprotein translocase subunit SecY A1E_04270 242 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 157803811 Common - Thiol:disulfide interchange protein DsbA A1E_03200 81 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 157803928 Common - capD protein A1E_03815 161 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157803856 Common - FTR1 family protein A1E_03425 31 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 157803794 Pathogen - hypothetical protein A1E_03115 1 None None None 157803227 Common rpsR 30S ribosomal protein S18 A1E_00190 208 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 157803497 Common - GTP-binding protein LepA A1E_01580 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 157804231 Common tig trigger factor A1E_05395 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 157803476 Common - Ribonuclease E A1E_01475 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 157804267 Pathogen - succinyl-diaminopimelate desuccinylase A1E_05600 1 None None None 157803640 Common - NADH dehydrogenase subunit N A1E_02295 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 157803220 Common - hypothetical protein A1E_00155 2 None None None 157803619 Common - hypothetical protein A1E_02190 1 None None None 157803508 Common gltX glutamyl-tRNA synthetase A1E_01635 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 157803865 Pathogen - hypothetical protein A1E_03470 1 None None None 157803536 Common - translation-associated GTPase A1E_01775 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 157803265 Common - protein-export membrane protein A1E_00395 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 157803898 Common - tyrosine recombinase A1E_03655 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157803945 Common - lipid-A-disaccharide synthase A1E_03910 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 157803252 Common argS arginyl-tRNA synthetase A1E_00315 2 None None None 157804168 Common - NADH dehydrogenase subunit H A1E_05080 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 157804102 Common lpxK tetraacyldisaccharide 4'-kinase A1E_04705 8 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 157804111 Common - lipoyl synthase A1E_04770 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 157803980 Common - hypothetical protein A1E_04085 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 157804097 Common - Guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein A1E_04680 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 157804049 Common - cell division protein FtsZ A1E_04440 1 None None None 157803670 Pathogen - hypothetical protein A1E_02445 1 None None None 157803797 Common - inorganic polyphosphate/ATP-NAD kinase A1E_03130 232 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 157803917 Common - 30S ribosomal protein S4 A1E_03760 223 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 157803597 Common - hypothetical protein A1E_02080 2 None None None 157803534 Common - peptidyl-tRNA hydrolase A1E_01765 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 157803723 Common - F pilus assembly protein TraB A1E_02715 2 None None None 157804144 Common - hypothetical protein A1E_04960 14 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 157804064 Common - Formamidopyrimidine-DNA glycosidase A1E_04515 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 157804186 Common - hypothetical protein A1E_05170 1 None None None 157804012 Common - 30S ribosomal protein S11 A1E_04255 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 157803507 Common groEL chaperonin GroEL A1E_01630 1 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 157803568 Common - preprotein translocase subunit YajC A1E_01935 11 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 157803241 Common ndk nucleoside diphosphate kinase A1E_00260 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 157803645 Common - hypothetical protein A1E_02320 2 None None None 157803522 Common - nitrogen regulation protein ntrY A1E_01705 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 157804206 Common - 190-KDa cell surface antigen A1E_05270 141 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 157803867 Common - hypothetical protein A1E_03480 1 None None None 157804243 Pathogen - hypothetical protein A1E_05465 1 None None None 157803952 Common - hypothetical protein A1E_03945 150 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 157803651 Common - putrescine-ornithine antiporter A1E_02350 175 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 157803783 Common - DNA helicase II A1E_03035 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 157803410 Pathogen - hypothetical protein A1E_01145 1 None None None 157803218 Common - hypothetical protein A1E_00145 10 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 157803487 Common - isocitrate dehydrogenase A1E_01530 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 157803590 Pathogen - hypothetical protein A1E_02045 1 None None None 157803394 Common rnhB ribonuclease HII A1E_01050 208 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 157804122 Common - aspartate kinase A1E_04825 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 157803547 Common - hypothetical protein A1E_01830 22 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 157804076 Common - Predicted ATPase A1E_04575 65 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 157803420 Pathogen - hypothetical protein A1E_01195 1 None None None 157804054 Common ksgA dimethyladenosine transferase A1E_04465 89 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 157804052 Common - dimethyladenosine transferase A1E_04455 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 157803847 Pathogen - hypothetical protein A1E_03380 1 None None None 157803937 Common - glutamyl-tRNA synthetase A1E_03870 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 157803332 Pathogen - leucyl aminopeptidase A1E_00740 1 None None None 157803965 Common - hypothetical protein A1E_04010 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803693 Pathogen - hypothetical protein A1E_02565 1 None None None 157803376 Pathogen - hypothetical protein A1E_00960 1 None None None 157803996 Common - hypothetical protein A1E_04175 38 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 157803756 Common - Predicted transcriptional regulator A1E_02900 40 COG1396 HipB, Predicted transcriptional regulators Transcription 157804226 Common - single-strand DNA-binding protein A1E_05370 10 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 157803599 Pathogen - hypothetical protein A1E_02090 1 None None None 157803635 Common - aromatic acid decarboxylase A1E_02270 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 157803198 Common - nifR3-like protein A1E_00045 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 157803465 Common murC UDP-N-acetylmuramate--L-alanine ligase A1E_01420 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 157803763 Common - hypothetical protein A1E_02935 2 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 157803884 Common - Proline/betaine transporter A1E_03575 113 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 157803301 Common secF preprotein translocase subunit SecF A1E_00585 187 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 157803858 Common - hypothetical protein A1E_03435 60 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 157804118 Common - hypothetical protein A1E_04805 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 157803685 Common - hypothetical protein A1E_02520 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 157804137 Common - hypothetical protein A1E_04925 1 None None None 157804021 Common rpsH 30S ribosomal protein S8 A1E_04300 230 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 157803455 Common pleD response regulator PleD A1E_01370 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 157803970 Pathogen - hypothetical protein A1E_04035 1 None None None 157804217 Common - Ferredoxin A1E_05325 167 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 157803925 Common - probable glycosyltransferase A1E_03800 160 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157803609 Pathogen - hypothetical protein A1E_02140 1 None None None 157803602 Common - hypothetical protein A1E_02105 89 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 157803221 Pathogen - hypothetical protein A1E_00160 1 None None None 157803668 Common - porphobilinogen deaminase A1E_02435 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 157804134 Common - hypothetical protein A1E_04910 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 157803468 Common - cell division protein ftsQ A1E_01435 61 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 157803932 Common - hypothetical protein A1E_03835 69 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 157804215 Common - possible outer surface protein A1E_05315 9 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 157804113 Common - Serine esterase A1E_04780 81 COG0400 COG0400, Predicted esterase General function prediction only 157803979 Pathogen - hypothetical protein A1E_04080 1 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 157803987 Pathogen - hypothetical protein A1E_04125 1 None None None 157804110 Common - hypothetical protein A1E_04765 108 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 157803389 Common - hypothetical protein A1E_01025 75 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 157803872 Common - hypothetical protein A1E_03505 8 None None None 157804172 Common atpC F0F1 ATP synthase subunit epsilon A1E_05100 93 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 157804065 Common - Mannose-1-phosphate guanylyltransferase A1E_04520 1 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 157803694 Common clpP ATP-dependent Clp protease proteolytic subunit A1E_02570 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157804056 Pathogen - hypothetical protein A1E_04475 1 None None None 157804082 Common - Ribosomal-protein-alanine acetyltransferase A1E_04605 83 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 157803782 Pathogen - hypothetical protein A1E_03030 1 None None None 157803396 Common - Glutaredoxin, GrxC family protein A1E_01060 119 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 157804120 Common rplU 50S ribosomal protein L21 A1E_04815 208 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 157803398 Pathogen - hypothetical protein A1E_01085 1 None None None 157803881 Pathogen - hypothetical protein A1E_03560 1 None None None 157803540 Pathogen - hypothetical protein A1E_01795 1 None None None 157803193 Common - hypothetical protein A1E_00020 116 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 157803766 Common - polynucleotide phosphorylase/polyadenylase A1E_02950 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 157803382 Common - Hydrophobe/amphiphile efflux-1 HAE1 family protein A1E_00990 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 157803423 Pathogen - hypothetical protein A1E_01210 1 None None None 157803938 Pathogen - hypothetical protein A1E_03875 1 None None None 157803378 Common - Transposase and inactivated derivative A1E_00970 1 None None None 157804013 Common rpsM 30S ribosomal protein S13 A1E_04260 224 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 157803759 Common truB tRNA pseudouridine synthase B A1E_02915 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 157803913 Pathogen - hypothetical protein A1E_03740 1 None None None 157803316 Pathogen - hypothetical protein A1E_00660 1 None None None 157804269 Common - lipoyltransferase A1E_05610 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 157803413 Common - hypothetical protein A1E_01160 5 None None None 157803888 Common - lysyl-tRNA synthetase A1E_03595 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 157803525 Pathogen - hypothetical protein A1E_01720 1 None None None 157803808 Common - succinyl-CoA synthetase alpha subunit A1E_03185 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 157803801 Common - recombination protein RecR A1E_03150 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 157804254 Pathogen - hypothetical protein A1E_05520 1 None None None 157803792 Common - hypothetical protein A1E_03105 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 157803821 Common - leucyl-tRNA synthetase A1E_03250 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803863 Common - Holliday junction DNA helicase RuvB A1E_03460 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 157804227 Pathogen - hypothetical protein A1E_05375 1 None None None 157803250 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein A1E_00305 162 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 157803505 Common - chaperonin GroEL A1E_01620 241 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 157804040 Common fumC fumarate hydratase A1E_04395 228 COG0114 FumC, Fumarase Energy production and conversion 157803614 Pathogen - hypothetical protein A1E_02165 1 None None None 157804045 Common - NifU-like domain A1E_04420 93 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 157803775 Common - Probable sigma(54) modulation protein A1E_02995 91 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 157803658 Common - Lysine efflux permease A1E_02385 73 COG1279 COG1279, Lysine efflux permease General function prediction only 157803324 Common rplA 50S ribosomal protein L1 A1E_00700 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 157803744 Common infC translation initiation factor IF-3 A1E_02840 59 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 157803672 Pathogen - hypothetical protein A1E_02455 1 None None None 157803921 Common - Efflux transporter, RND family, MFP subunit A1E_03780 134 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 157803828 Common - hypothetical protein A1E_03285 3 None None None 157803263 Common - S-adenosylmethionine transporter A1E_00385 99 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 157803579 Common - translocase A1E_01990 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 157803351 Pathogen - hypothetical protein A1E_00835 1 None None None 157804189 Common - Iojap-related protein A1E_05185 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 157803283 Common - GTP-binding protein A1E_00485 178 COG0218 COG0218, Predicted GTPase General function prediction only 157803281 Common rpmB 50S ribosomal protein L28 A1E_00475 100 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 157803964 Pathogen - hypothetical protein A1E_04005 1 None None None 157804203 Common - Phospholipase D (PLD) superfamily protein A1E_05255 52 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 157803530 Common rplT 50S ribosomal protein L20 A1E_01745 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 157803947 Pathogen - hypothetical protein A1E_03920 1 None None None 157803271 Common - 3-deoxy-D-manno-octulosonic-acid transferase A1E_00425 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 157803765 Common - abc transporter atp-binding protein (abct2) A1E_02945 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 157804184 Common - ATPase (AAA+ superfamily)-like protein A1E_05160 11 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 157803616 Common - hypothetical protein A1E_02175 1 None None None 157803580 Common - NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain A1E_01995 1 None None None 157804171 Common - aconitate hydratase A1E_05095 223 COG1048 AcnA, Aconitase A Energy production and conversion 157803238 Common - hypothetical protein A1E_00245 2 None None None 157803259 Common - hypothetical protein A1E_00350 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 157804127 Common - aspartate kinase A1E_04850 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 157803467 Common - D-alanylalanine synthetase A1E_01430 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 157804262 Common - hypothetical protein A1E_05575 37 COG0795 COG0795, Predicted permeases General function prediction only 157803831 Pathogen - RND efflux system, outer membrane protein A1E_03300 1 None None None 157803622 Common nusA transcription elongation factor NusA A1E_02205 216 COG0195 NusA, Transcription elongation factor Transcription 157804010 Common rplQ 50S ribosomal protein L17 A1E_04245 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 157804178 Pathogen - hypothetical protein A1E_05130 1 None None None 157804277 Pathogen - hypothetical protein A1E_05650 1 None None None 157803296 Common trmD tRNA (guanine-N(1)-)-methyltransferase A1E_00560 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 157803438 Pathogen - hypothetical protein A1E_01285 1 None None None 157803442 Common - hypothetical protein A1E_01305 1 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 157804153 Common - Type IV secretion/conjugal transfer ATPase, VirB4 family protein A1E_05005 42 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 157804235 Pathogen - hypothetical protein A1E_05415 1 None None None 157803431 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase A1E_01250 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 157803731 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 A1E_02755 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 157803739 Common - Superoxide dismutase A1E_02815 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 157803512 Common - hypothetical protein A1E_01655 1 None None None 157803318 Common rpsL 30S ribosomal protein S12 A1E_00670 244 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 157803682 Common - hypothetical protein A1E_02505 45 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 157803893 Common - apolipoprotein N-acyltransferase A1E_03630 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 157804252 Common - transcription elongation factor GreA A1E_05510 204 COG0782 GreA, Transcription elongation factor Transcription 157803714 Common - Tetratricopeptide repeat-containing protein A1E_02670 2 None None None 157803816 Common - Osmolarity sensor protein EnvZ A1E_03225 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157803994 Common - hypothetical protein A1E_04165 152 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 157803806 Common - acylamino-acid-releasing enzyme A1E_03175 122 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 157803450 Common rplM 50S ribosomal protein L13 A1E_01345 217 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 157803273 Common - aspartate aminotransferase A1E_00435 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 157803851 Common - Thiol:disulfide interchange protein TlpA A1E_03400 108 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 157803838 Common - hypothetical protein A1E_03335 1 None None None 157803305 Common - tRNA/rRNA methyltransferase A1E_00605 154 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 157803951 Common - hypothetical protein A1E_03940 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 157804039 Pathogen - hypothetical protein A1E_04390 1 None None None 157803879 Pathogen - hypothetical protein A1E_03550 1 None None None 157804002 Pathogen - hypothetical protein A1E_04205 1 None None None 157803217 Common - hypothetical protein A1E_00140 123 COG1678 COG1678, Putative transcriptional regulator Transcription 157803870 Common - prolyl-tRNA synthetase A1E_03495 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157804072 Common - 4-hydroxybenzoate octaprenyltransferase A1E_04555 158 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 157803537 Common - hypothetical protein A1E_01780 1 None None None 157803261 Pathogen - hypothetical protein A1E_00370 1 None None None 157804245 Common - hypothetical protein A1E_05475 1 None None None 157803485 Pathogen - hypothetical protein A1E_01520 1 None None None 157804107 Common - Poly-beta-hydroxybutyrate polymerase A1E_04750 1 None None None 157803520 Common - 30S ribosomal protein S21 A1E_01695 2 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 157803819 Common - hypothetical protein A1E_03240 22 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 157803493 Common - Cytochrome b A1E_01560 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 157803705 Common - Conjugal transfer protein TraA A1E_02625 1 None None None 157804030 Common rplV 50S ribosomal protein L22 A1E_04345 222 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 157803904 Common - hypothetical protein A1E_03685 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 157804282 Common hemE uroporphyrinogen decarboxylase A1E_05675 180 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 157803320 Common - elongation factor G A1E_00680 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 157803290 Common - hypothetical protein A1E_00520 21 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 157803552 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase A1E_01855 214 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 157803336 Common - hypothetical protein A1E_00760 127 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 157803515 Pathogen - hypothetical protein A1E_01670 1 None None None 157804146 Common - DNA polymerase I A1E_04970 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 157803405 Common coaE dephospho-CoA kinase A1E_01120 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 157803666 Common - tryptophanyl-tRNA synthetase A1E_02425 227 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803776 Pathogen - hypothetical protein A1E_03000 1 None None None 157803770 Common - ribonucleotide-diphosphate reductase alpha subunit A1E_02970 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 157803915 Common - hypothetical protein A1E_03750 11 None None None 157803629 Common - N6-adenine-specific methylase A1E_02240 198 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 157803343 Common pyrH uridylate kinase A1E_00795 245 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 157803326 Common rplL 50S ribosomal protein L7/L12 A1E_00710 212 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 157803384 Common - hypothetical protein A1E_01000 204 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 157803356 Common - hypothetical protein A1E_00860 1 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 157803191 Common - Thioredoxin A1E_00010 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 157803768 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase A1E_02960 5 None None None 157804058 Common - GTP-binding protein EngA A1E_04485 234 COG1160 COG1160, Predicted GTPases General function prediction only 157803360 Common - hypothetical protein A1E_00880 1 None None None 157803726 Common cmk cytidylate kinase A1E_02730 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157803542 Pathogen - hypothetical protein A1E_01805 1 None None None 157804249 Common - RNA polymerase sigma factor RpoD A1E_05495 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 157803415 Pathogen - hypothetical protein A1E_01170 1 None None None 157803459 Common - phosphatidylserine decarboxylase A1E_01390 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 157803445 Common - tail-specific protease precursor A1E_01320 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 157803604 Common - Multisubunit Na+/H+ antiporter, MnhF subunit A1E_02115 1 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 157803966 Common - hypothetical protein A1E_04015 184 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 157803557 Common - hypothetical protein A1E_01880 1 None None None 157803985 Common - hypothetical protein A1E_04110 2 None None None 157803461 Common - Multidrug resistance protein A A1E_01400 151 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 157804132 Common acpP acyl carrier protein A1E_04875 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157803634 Common - replicative DNA helicase A1E_02265 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 157804020 Common rplF 50S ribosomal protein L6 A1E_04295 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 157803424 Common fmt methionyl-tRNA formyltransferase A1E_01215 102 COG1485 COG1485, Predicted ATPase General function prediction only 157804160 Common - NADH dehydrogenase subunit K A1E_05040 163 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 157803680 Common - biotin synthesis protein BioC A1E_02495 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 157803755 Common - hypothetical protein A1E_02895 73 COG1295 Rbn, Predicted membrane protein Function unknown 157804115 Common - Endonuclease III A1E_04790 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 157803661 Common - hypothetical protein A1E_02400 2 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 157804061 Common - hypothetical protein A1E_04500 1 None None None 157803842 Common - Virginiamycin A acetyltransferase A1E_03355 67 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 157803861 Common - AmpG protein A1E_03450 114 None None None 157803700 Common - Integrase, catalytic region A1E_02600 21 None None None 157803948 Pathogen - hypothetical protein A1E_03925 1 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 157804084 Common - multidrug resistance protein A1E_04615 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 157803471 Common - hypothetical protein A1E_01450 1 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157803195 Common - UDP-N-acetylglucosamine acyltransferase A1E_00030 146 COG1043 LpxA, Acyl- acyl carrier protein 157803566 Common - Sco2 protein precursor A1E_01925 106 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 157803674 Pathogen - hypothetical protein A1E_02465 1 None None None 157804019 Common rplR 50S ribosomal protein L18 A1E_04290 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 157804101 Common - Periplasmic protein A1E_04700 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 157803742 Common - hypothetical protein A1E_02830 6 COG4285 COG4285, Uncharacterized conserved protein Function unknown 157803696 Common - cytidylate kinase A1E_02580 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 157803407 Common - hypothetical protein A1E_01130 31 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 157803400 Common - ATP-dependent helicase A1E_01095 230 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 157803358 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase A1E_00870 29 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 157804213 Common - hypothetical protein A1E_05305 1 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 157803223 Pathogen - hypothetical protein A1E_00170 1 None None None 157804067 Common - Poly-beta-hydroxyalkanoate depolymerase A1E_04530 2 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 157804195 Pathogen - hypothetical protein A1E_05215 1 None None None 157803977 Common - hypothetical protein A1E_04070 50 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 157803656 Common - transposase IS200-family protein A1E_02375 59 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157803285 Common - Type IV secretory pathway, VirB3-like protein A1E_00495 17 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 157803918 Common - Glycosyltransferase A1E_03765 180 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157803835 Pathogen - hypothetical protein A1E_03320 1 None None None 157803911 Common - hypothetical protein A1E_03720 6 None None None 157804225 Common - single-strand DNA-binding protein A1E_05365 199 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 157803943 Common - hypothetical protein A1E_03900 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 157803592 Common - Type I site-specific restriction-modification system, R (restriction) subunit A1E_02055 53 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 157804086 Common - bicyclomycin resistance protein A1E_04625 1 None None None 157803391 Common - DNA polymerase III subunit delta' A1E_01035 100 COG0633 Fdx, Ferredoxin Energy production and conversion 157803257 Common - preprotein translocase subunit SecB A1E_00340 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157803246 Common - putative ABC transporter ATP-binding component A1E_00285 1 None None None 157803314 Common - hypothetical protein A1E_00650 26 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 157804027 Common rpmC 50S ribosomal protein L29 A1E_04330 1 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 157804256 Common - DNA polymerase III subunits gamma and tau A1E_05545 243 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 157803823 Common - DNA polymerase III subunit beta A1E_03260 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 157804095 Pathogen - hypothetical protein A1E_04670 1 None None None 157803741 Common - BioY family protein A1E_02825 91 COG1268 BioY, Uncharacterized conserved protein General function prediction only 157804141 Common gmk guanylate kinase A1E_04945 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 157804079 Pathogen - hypothetical protein A1E_04590 1 None None None 157803814 Common - branched-chain amino acid aminotransferase A1E_03215 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 157804042 Common - cell division protein FtsZ A1E_04405 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 157803934 Common - hypothetical protein A1E_03845 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 157803436 Pathogen - hypothetical protein A1E_01275 1 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 157803737 Common - biotin--protein ligase A1E_02785 210 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 157803510 Common - 3-demethylubiquinone-9 3-methyltransferase A1E_01645 83 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 157804017 Common rpmD 50S ribosomal protein L30 A1E_04280 136 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 157803268 Common cysS cysteinyl-tRNA synthetase A1E_00410 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157804035 Common rplC 50S ribosomal protein L3 A1E_04370 225 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 157803840 Common - hypothetical protein A1E_03345 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 157803788 Common - transposase IS200-family protein A1E_03085 10 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157804070 Common - thymidylate kinase A1E_04545 225 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 157804233 Common - citrate synthase A1E_05405 192 COG0372 GltA, Citrate synthase Energy production and conversion 157803891 Common - hypothetical protein A1E_03620 63 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 157803853 Common - hypothetical protein A1E_03410 2 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 157803550 Common - hypothetical protein A1E_01845 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 157803618 Common - tyrosyl-tRNA synthetase A1E_02185 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803874 Common - 3-deoxy-manno-octulosonate cytidylyltransferase A1E_03515 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 157803474 Common - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase A1E_01465 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 157803825 Common - phenylalanyl-tRNA synthetase alpha subunit A1E_03270 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 157803532 Common rpmI 50S ribosomal protein L35 A1E_01755 173 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 157803589 Common - hypothetical protein A1E_02040 58 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 157803624 Pathogen - hypothetical protein A1E_02215 1 COG5412 COG5412, Phage-related protein Function unknown 157803365 Common - DnaJ A1E_00905 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 157803908 Common - hypothetical protein A1E_03705 182 COG0759 COG0759, Uncharacterized conserved protein Function unknown 157803961 Common - hypothetical protein A1E_03990 139 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 157803833 Common - N-acetylglucosaminyl transferase A1E_03310 212 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 157804279 Common - coproporphyrinogen III oxidase A1E_05660 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 157803781 Common - hypothetical protein A1E_03025 2 None None None 157804240 Common glyS glycyl-tRNA synthetase subunit beta A1E_05440 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 157804176 Common - F0F1 ATP synthase subunit delta A1E_05120 152 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 157804281 Common hemH ferrochelatase A1E_05670 176 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 157803689 Common - hypothetical protein A1E_02545 1 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 157803208 Common - F0F1 ATP synthase subunit C A1E_00095 36 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 157803248 Pathogen - hypothetical protein A1E_00295 1 None None None 157803549 Common - hypothetical protein A1E_01840 216 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 157803298 Common rplS 50S ribosomal protein L19 A1E_00570 37 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 157803906 Pathogen - hypothetical protein A1E_03695 1 None None None 157803707 Common - Conjugal transfer protein TraA A1E_02635 1 None None None 157803386 Common - Bifunctional penicillin-binding protein 1C A1E_01010 1 None None None 157803490 Common - Heme exporter protein B A1E_01545 2 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 157803334 Common aspS aspartyl-tRNA synthetase A1E_00750 128 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 157804162 Common - NADH dehydrogenase subunit M A1E_05050 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 157803292 Common - GTPase EngB A1E_00540 2 None None None 157803716 Common - hypothetical protein A1E_02680 1 None None None 157803328 Common - DNA-directed RNA polymerase beta' subunit A1E_00720 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 157804270 Common lipB lipoyltransferase A1E_05615 108 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 157803341 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C A1E_00785 106 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 157804130 Common recA recombinase A A1E_04865 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 157803307 Common - Mrp protein A1E_00615 232 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 157803641 Pathogen - hypothetical protein A1E_02300 1 None None None 157803447 Common - hypothetical protein A1E_01330 35 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 157804037 Common - elongation factor Tu A1E_04380 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 157803502 Common - ribonuclease PH A1E_01605 185 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 157804125 Pathogen - hypothetical protein A1E_04840 1 None None None 157803753 Common - hypothetical protein A1E_02885 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 157803559 Common - ATP-dependent DNA helicase RecG A1E_01890 234 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 157803482 Common - dihydrolipoamide acetyltransferase A1E_01505 211 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 157804247 Common alaS alanyl-tRNA synthetase A1E_05485 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803539 Pathogen - hypothetical protein A1E_01790 1 None None None 157804009 Common rpsT 30S ribosomal protein S20 A1E_04240 145 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 157803219 Pathogen - hypothetical protein A1E_00150 1 None None None 157803230 Common rplI 50S ribosomal protein L9 A1E_00205 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 157803956 Common - hypothetical protein A1E_03965 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 157803577 Common - 4'-phosphopantetheinyl transferase A1E_01980 148 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 157804008 Common - putative monovalent cation/H+ antiporter subunit D A1E_04235 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 157804201 Common - Maf-like protein A1E_05245 158 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 157804155 Common - tellurium resistance protein TerC A1E_05015 89 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 157803211 Common - Protein-disulfide isomerase A1E_00110 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 157804207 Common - Cell division protein FtsK-like protein A1E_05275 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 157803955 Common - hypothetical protein A1E_03960 234 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 157803594 Common - S-adenosyl-methyltransferase MraW A1E_02065 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 157803791 Common - thioredoxin reductase A1E_03100 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 157804088 Pathogen - hypothetical protein A1E_04635 1 None None None 157804048 Pathogen - hypothetical protein A1E_04435 1 None None None 157803697 Common - hypothetical protein A1E_02585 2 None None None 157803699 Pathogen - hypothetical protein A1E_02595 1 None None None 157803780 Common - threonine dehydratase A1E_03020 221 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 157803489 Common - hypothetical protein A1E_01540 69 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 157803480 Common - exodeoxyribonuclease III A1E_01495 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 157804103 Pathogen - hypothetical protein A1E_04710 1 None None None 157803712 Common - Putative conjugative transfer protein TraD A1E_02660 2 None None None 157803841 Common - Cytochrome c oxidase polypeptide II A1E_03350 155 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 157803197 Common - UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase A1E_00040 159 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 157803312 Common - Succinate dehydrogenase cytochrome b-556 subunit A1E_00640 74 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 157803735 Common - hypothetical protein A1E_02775 1 None None None 157803778 Pathogen - hypothetical protein A1E_03010 1 None None None 157804131 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase A1E_04870 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 157804069 Common - methionyl-tRNA synthetase A1E_04540 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803761 Common - polyribonucleotide nucleotidyltransferase A1E_02925 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 157803654 Common - hypothetical protein A1E_02365 3 None None None 157804025 Common rplN 50S ribosomal protein L14 A1E_04320 245 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 157803798 Common - hypothetical protein A1E_03135 1 None None None 157804271 Common rpsP 30S ribosomal protein S16 A1E_05620 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 157803416 Common - hypothetical protein A1E_01175 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 157803632 Common - hypothetical protein A1E_02255 1 None None None 157803287 Common - TrbL/VirB6 plasmid Conjugative transfer protein A1E_00505 9 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 157803975 Common - hypothetical protein A1E_04060 32 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 157803371 Common - dihydrolipoamide acetyltransferase A1E_00935 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 157803676 Common - hypothetical protein A1E_02475 17 COG1723 COG1723, Uncharacterized conserved protein Function unknown 157803639 Common - delta-aminolevulinic acid dehydratase A1E_02290 1 None None None 157803729 Common rho transcription termination factor Rho A1E_02745 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 157803868 Pathogen - hypothetical protein A1E_03485 1 None None None 157803960 Common - hypothetical protein A1E_03985 10 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 157804242 Common - hypothetical protein A1E_05450 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 157804220 Common - Cation diffusion facilitator family transporter A1E_05340 181 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 157803901 Common - NADH dehydrogenase alpha subunit A1E_03670 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 157803941 Common - hypothetical protein A1E_03890 1 None None None 157803393 Common hscB co-chaperone HscB A1E_01045 49 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 157803605 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase A1E_02120 114 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 157803452 Common - D-alanyl-D-alanine dipeptidase A1E_01355 7 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 157803983 Common - hypothetical protein A1E_04100 1 None None None 157804177 Common - dihydrolipoamide dehydrogenase A1E_05125 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 157804093 Common - cytochrome c-type biogenesis protein ccmF A1E_04660 137 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 157804138 Common - Rod shape-determining protein MreC A1E_04930 156 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 157804114 Common - Glutaredoxin-like protein grla A1E_04785 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 157803883 Common - hypothetical protein A1E_03570 1 None None None 157804117 Common - ABC-type transport systems periplasmic component A1E_04800 17 None None None 157804063 Common - ubiquinone/menaquinone biosynthesis methyltransferase A1E_04510 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 157803554 Common - hypothetical protein A1E_01865 1 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 157803385 Pathogen - hypothetical protein A1E_01005 1 None None None 157803748 Pathogen - hypothetical protein A1E_02860 1 None None None 157804218 Common - Heme exporter protein C A1E_05330 113 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 157804051 Pathogen - hypothetical protein A1E_04450 1 None None None 157804211 Common - hypothetical protein A1E_05295 3 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 157803936 Common - DNA topoisomerase I A1E_03865 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 157804109 Common - acetyl-CoA acetyltransferase A1E_04760 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 157804264 Common - succinyl-diaminopimelate desuccinylase A1E_05585 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 157804164 Pathogen - hypothetical protein A1E_05060 1 None None None 157803848 Common - Soluble lytic murein transglycosylase precursor A1E_03385 147 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 157803319 Common - 30S ribosomal protein S7 A1E_00675 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 157803427 Common - hypothetical protein A1E_01230 1 None None None 157803564 Common - inorganic pyrophosphatase A1E_01915 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 157804154 Common - hypothetical protein A1E_05010 2 None None None 157803373 Common - Periplasmic divalent cation tolerance protein A1E_00945 108 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 157803270 Common tsf elongation factor Ts A1E_00420 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 157804092 Common - hypothetical protein A1E_04655 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 157803998 Common - hypothetical protein A1E_04185 3 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 157803354 Common - 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase A1E_00850 143 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 157803446 Common - Histidine kinase sensor protein A1E_01325 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157804191 Pathogen - hypothetical protein A1E_05195 1 None None None 157803728 Common - Putative methyltransferase A1E_02740 26 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 157803309 Common - hflc protein (hflc) A1E_00625 216 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 157803544 Common - hypothetical protein A1E_01815 33 COG3621 COG3621, Patatin General function prediction only 157804053 Common - hypothetical protein A1E_04460 19 None None None 157804198 Pathogen - dihydrolipoamide dehydrogenase A1E_05230 1 None None None 157803959 Common - hypothetical protein A1E_03980 204 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 157804143 Common - 50S ribosomal protein L32 A1E_04955 102 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 157803369 Common dnaK molecular chaperone DnaK A1E_00925 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 157803401 Common - excinuclease ABC subunit B A1E_01100 50 COG3346 COG3346, Uncharacterized conserved protein Function unknown 157803662 Common - hypothetical protein A1E_02405 89 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 157803500 Common - hypothetical protein A1E_01595 122 COG0628 PerM, Predicted permease General function prediction only 157804156 Common - hypothetical protein A1E_05020 1 None None None 157803213 Common - F0F1 ATP synthase subunit A A1E_00120 44 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 157804016 Common rplO 50S ribosomal protein L15 A1E_04275 95 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 157803575 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase A1E_01970 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 157804192 Pathogen - hypothetical protein A1E_05200 1 None None None 157803688 Pathogen - hypothetical protein A1E_02540 1 None None None 157803470 Pathogen - hypothetical protein A1E_01445 1 None None None 157803993 Common - hypothetical protein A1E_04160 72 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 157803669 Common - Microcin C7 resistance protein A1E_02440 1 None None None 157803556 Common - Succinyl-CoA:3-ketoacid-coenzyme A transferase A1E_01875 89 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 157803926 Common - hypothetical protein A1E_03805 5 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 157803387 Pathogen - hypothetical protein A1E_01015 1 None None None 157803772 Common - hypothetical protein A1E_02980 1 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 157803299 Common - protein export protein SecF A1E_00575 216 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 157803232 Common sdhB succinate dehydrogenase iron-sulfur subunit A1E_00215 93 COG1565 COG1565, Uncharacterized conserved protein Function unknown 157803463 Common - hypothetical protein A1E_01410 42 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 157803449 Common - DNA topoisomerase IV subunit B A1E_01340 77 COG1520 COG1520, FOG: WD40-like repeat Function unknown 157803367 Common - hypothetical protein A1E_00915 115 COG4105 ComL, DNA uptake lipoprotein General function prediction only 157803348 Common - putative monovalent cation/H+ antiporter subunit E A1E_00820 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 157803827 Common - diaminopimelate epimerase A1E_03280 195 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 157804230 Common - 5-aminolevulinate synthase A1E_05390 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 157803498 Common - hypothetical protein A1E_01585 1 None None None 157803418 Common - DNA gyrase subunit A A1E_01185 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 157803206 Common - F0F1 ATP synthase subunit B A1E_00085 1 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 157803802 Common - hypothetical protein A1E_03155 24 COG1714 COG1714, Predicted membrane protein/domain Function unknown 157804257 Common - hypothetical protein A1E_05550 141 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 157803876 Common - ADP,ATP carrier protein A1E_03535 8 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 157803226 Common rpsF 30S ribosomal protein S6 A1E_00185 197 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 157804266 Pathogen - hypothetical protein A1E_05595 1 None None None 157803626 Common - DNA repair protein RecO A1E_02225 36 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 157803479 Common - Penicillin-binding protein 4* A1E_01490 114 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 157804250 Common - DNA primase A1E_05500 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 157803962 Common - hypothetical protein A1E_03995 150 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 157803584 Common - Type I restriction-modification system, M subunit A1E_02015 3 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 157804239 Common - bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase A1E_05435 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 157803300 Common - NADH dehydrogenase I chain F A1E_00580 163 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 157804273 Common - DNA mismatch repair protein A1E_05630 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 157803411 Pathogen - hypothetical protein A1E_01150 1 None None None 157804174 Common - F0F1 ATP synthase subunit gamma A1E_05110 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 157803646 Pathogen - hypothetical protein A1E_02325 1 None None None 157803717 Common - Conjugative transfer protein TraG A1E_02685 1 None None None 157804183 Pathogen - hypothetical protein A1E_05155 1 None None None 157804128 Common - tRNA modification GTPase A1E_04855 219 COG0486 ThdF, Predicted GTPase General function prediction only 157803855 Common - hypothetical protein A1E_03420 19 None None None 157803253 Common - DNA topoisomerase IV subunit A A1E_00320 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 157803710 Common - Conjugal transfer protein TraA A1E_02650 1 None None None 157803529 Common - hypothetical protein A1E_01740 24 None None None 157803834 Common - Cell division protein FtsW A1E_03315 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 157804077 Common - hypothetical protein A1E_04580 92 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 157803509 Common - 3-demethylubiquinone-9 3-methyltransferase A1E_01640 149 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 157803277 Common - alanine racemase A1E_00455 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 157803435 Pathogen - hypothetical protein A1E_01270 1 None None None 157803233 Common - prolipoprotein diacylglyceryl transferase A1E_00220 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 157803812 Common - SsrA-binding protein A1E_03205 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 157803897 Common - hypothetical protein A1E_03650 1 None None None 157803562 Common - virulence factor mviN A1E_01905 190 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 157803890 Common - ABC transporter permease protein A1E_03605 1 None None None 157803652 Common - hypothetical protein A1E_02355 214 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 157803280 Common alr alanine racemase A1E_00470 1 None None None 157803762 Common - KpsF protein A1E_02930 172 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 157803988 Pathogen - hypothetical protein A1E_04130 1 None None None 157803796 Common - threonine dehydratase A1E_03125 150 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 157803713 Common - Putative conjugative transfer protein TraD A1E_02665 2 None None None 157803317 Common sdhA succinate dehydrogenase flavoprotein subunit A1E_00665 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 157803916 Common - protoheme IX farnesyltransferase A1E_03755 178 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 157803535 Common - peptidyl-tRNA hydrolase A1E_01770 1 None None None 157803692 Pathogen - hypothetical protein A1E_02560 1 None None None 157803289 Common - VirB6-like protein of the type IV secretion system A1E_00515 13 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 157803745 Common - pyruvate phosphate dikinase A1E_02845 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 157803251 Common - arginyl-tRNA synthetase A1E_00310 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157803266 Common - hypothetical protein A1E_00400 48 COG1738 COG1738, Uncharacterized conserved protein Function unknown 157803899 Common - hypothetical protein A1E_03660 13 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 157803573 Common - HAD-superfamily subfamily IIA hydrolase A1E_01960 50 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 157803678 Common hemC porphobilinogen deaminase A1E_02485 75 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 157803523 Common - hypothetical protein A1E_01710 6 None None None 157804098 Common clpX ATP-dependent protease ATP-binding subunit A1E_04685 173 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 157803866 Common - Holliday junction DNA helicase motor protein A1E_03475 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 157803807 Common - succinyl-CoA synthetase subunit beta A1E_03180 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 157803403 Common - dephospho-CoA kinase A1E_01110 122 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 157803249 Common - 2-dehydro-3-deoxyphosphooctonate aldolase A1E_00300 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 157803596 Common - Penicillin-binding protein A1E_02075 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 157803757 Common - Cell surface antigen A1E_02905 12 None None None 157803746 Pathogen - hypothetical protein A1E_02850 1 None None None 157803310 Common ruvC Holliday junction resolvase A1E_00630 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 157804181 Pathogen - hypothetical protein A1E_05145 1 None None None 157803953 Common - hypothetical protein A1E_03950 2 None None None 157803242 Common - glucose-inhibited division protein A A1E_00265 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 157803569 Common - Magnesium transporter A1E_01940 159 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 157804145 Common rpmF 50S ribosomal protein L32 A1E_04965 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 157803690 Pathogen - hypothetical protein A1E_02550 1 None None None 157803380 Common - DNA polymerase III subunit delta A1E_00980 33 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 157803375 Common - dihydrolipoamide acetyltransferase A1E_00955 1 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 157804166 Common - NADH dehydrogenase subunit I A1E_05070 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 157803846 Common - microcin C7 self-immunity protein A1E_03375 80 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 157803598 Common - Penicillin-binding protein A1E_02085 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 157803997 Common - hypothetical protein A1E_04180 27 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 157803784 Common - Glycosyltransferase A1E_03040 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 157803194 Common - putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase A1E_00025 116 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 157804123 Common - hypothetical protein A1E_04830 1 None None None 157804044 Common - Ecotin precursor A1E_04415 13 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 157804196 Common - Cell surface antigen-like protein Sca13 A1E_05220 1 None None None 157803331 Common - hypothetical protein A1E_00735 76 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 157803199 Common - hypothetical protein A1E_00050 200 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 157803546 Common - hypothetical protein A1E_01825 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 157804075 Pathogen - hypothetical protein A1E_04570 1 None None None 157803421 Common def peptide deformylase A1E_01200 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 157803981 Common - hypothetical protein A1E_04090 190 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 157804136 Common - guanylate kinase A1E_04920 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 157803454 Common - dinucleoside polyphosphate hydrolase A1E_01365 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 157803607 Pathogen - hypothetical protein A1E_02130 1 None None None 157804216 Common - Putative outer surface protein A1E_05320 9 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 157803924 Common - possible glycosyltransferase A1E_03795 3 None None None 157803878 Pathogen - hypothetical protein A1E_03545 1 None None None 157803362 Pathogen - hypothetical protein A1E_00890 1 None None None 157803464 Common - phosphatidylserine decarboxylase A1E_01415 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 157804119 Common glyA serine hydroxymethyltransferase A1E_04810 45 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 157803600 Common - hypothetical protein A1E_02095 1 None None None 157803428 Common - cytochrome d ubiquinol oxidase subunit I A1E_01235 163 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 157803885 Pathogen - hypothetical protein A1E_03580 1 None None None 157803750 Common - hypothetical protein A1E_02870 1 None None None 157804244 Common - hypothetical protein A1E_05470 2 None None None 157803302 Common rnc ribonuclease III A1E_00590 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 157803978 Common - hypothetical protein A1E_04075 1 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 157803703 Common - Proline/betaine transporter A1E_02615 124 None None None 157803294 Pathogen - hypothetical protein A1E_00550 1 COG0282 ackA, Acetate kinase Energy production and conversion 157804024 Common rplX 50S ribosomal protein L24 A1E_04315 196 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 157804148 Common - UDP-glucose 6-dehydrogenase A1E_04980 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 157803244 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA A1E_00275 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 157804214 Pathogen - hypothetical protein A1E_05310 1 None None None 157804151 Common dnaE DNA polymerase III subunit alpha A1E_04995 202 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 157803495 Common - putative monovalent cation/H+ antiporter subunit B A1E_01570 55 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 157803344 Common - hypothetical protein A1E_00800 20 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 157804205 Common - Parvulin-like peptidyl-prolyl isomerase A1E_05265 84 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 157803321 Common secE preprotein translocase subunit SecE A1E_00685 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 157803774 Common - Methylenetetrahydrofolate dehydrogenase A1E_02990 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 157803973 Common - hypothetical protein A1E_04050 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 157803338 Pathogen - hypothetical protein A1E_00770 1 None None None 157804081 Common - ATP-dependent protease ATP-binding subunit A1E_04600 232 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 157803991 Common - hypothetical protein A1E_04150 3 COG4695 COG4695, Phage-related protein Function unknown 157803346 Common - hypothetical protein A1E_00810 1 None None None 157803611 Pathogen - hypothetical protein A1E_02150 1 None None None 157803671 Pathogen - hypothetical protein A1E_02450 1 None None None 157804033 Common rplW 50S ribosomal protein L23 A1E_04360 32 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 157803836 Pathogen - hypothetical protein A1E_03325 1 None None None 157803638 Common - delta-aminolevulinic acid dehydratase A1E_02285 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 157803517 Pathogen - hypothetical protein A1E_01680 1 None None None 157803804 Common - ribosome-binding factor A A1E_03165 61 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 157803686 Common - UDP-N-acetylglucosamine pyrophosphorylase A1E_02525 219 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 157803526 Pathogen - hypothetical protein A1E_01725 1 None None None 157804090 Common - Lipoprotein releasing system ATP-binding protein LolD A1E_04645 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 157804229 Common - heat shock protein 90 A1E_05385 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 157803660 Common - hypothetical protein A1E_02395 1 None None None 157804268 Common - hypothetical protein A1E_05605 1 None None None 157804004 Common - Antitoxin of toxin-antitoxin system VapB A1E_04215 1 None None None 157803664 Common - hypothetical protein A1E_02415 3 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 157804158 Common - seryl-tRNA synthetase A1E_05030 48 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 157803201 Common - poly(A) polymerase A1E_00060 209 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 157804121 Common rpmA 50S ribosomal protein L27 A1E_04820 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 157804261 Common - hypothetical protein A1E_05570 5 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 157804005 Common - putative monovalent cation/H+ antiporter subunit D A1E_04220 1 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 157804032 Common rplB 50S ribosomal protein L2 A1E_04355 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 157803215 Common recF recombination protein F A1E_00130 2 None None None 157803810 Pathogen - hypothetical protein A1E_03195 1 None None None 157803857 Common - putative intracellular septation protein A1E_03430 59 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 157804188 Common - glutathione-regulated potassium-efflux system protein kefb (kefb) A1E_05180 184 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 157803578 Common - Protein export protein PrsA precursor A1E_01985 157 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 157803352 Common - hypothetical protein A1E_00840 2 None None None 157803722 Common - Putative conjugative transfer protein TraD A1E_02710 12 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 157803255 Common dcd deoxycytidine triphosphate deaminase A1E_00330 150 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 157803433 Pathogen - phosphoribosylaminoimidazole-succinocarboxamide synthase A1E_01260 1 None None None 157803235 Common - putative inner membrane protein translocase component YidC A1E_00230 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 157803895 Pathogen - hypothetical protein A1E_03640 1 None None None 157803684 Common - hypothetical protein A1E_02515 7 None None None 157803430 Common - Beta 1,4 glucosyltransferase A1E_01245 74 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 157803795 Pathogen - hypothetical protein A1E_03120 1 None None None 157803275 Common - vacJ lipoprotein precursor A1E_00445 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 157803560 Common - hypothetical protein A1E_01895 1 None None None 157803440 Common - transposase IS200-family protein A1E_01295 8 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157803844 Common - hypothetical protein A1E_03365 141 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 157803571 Pathogen - hypothetical protein A1E_01950 1 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 157803228 Common - 50S ribosomal protein L9 A1E_00195 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 157803929 Common - putative dTDP-4-dehydrorhamnose reductase A1E_03820 121 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 157803477 Common - Cytochrome c oxidase assembly protein A1E_01480 50 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 157803204 Common - Cell surface antigen Sca1 A1E_00075 3 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 157803496 Common prfB peptide chain release factor 2 A1E_01575 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 157804275 Common - Oxidoreductase A1E_05640 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 157804237 Common gltA type II citrate synthase A1E_05425 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 157803903 Common - NADH dehydrogenase subunit C A1E_03680 173 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 157803628 Common - DNA repair protein RadA A1E_02235 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 157803719 Common - hypothetical protein A1E_02695 1 None None None 157804014 Common adk adenylate kinase A1E_04265 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 157803582 Pathogen - hypothetical protein A1E_02005 1 None None None 157804169 Common - NADH dehydrogenase gamma subunit A1E_05085 191 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 157803457 Common - Extragenic suppressor protein SuhB A1E_01380 142 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 157803944 Common - hypothetical protein A1E_03905 1 None None None 157804259 Common - Glutamine ABC transporter ATP-binding protein A1E_05560 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 157803733 Common - hypothetical protein A1E_02765 1 COG5346 COG5346, Predicted membrane protein Function unknown 157803264 Common queF 7-cyano-7-deazaguanine reductase A1E_00390 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157803829 Pathogen - hypothetical protein A1E_03290 1 None None None 157803648 Common - NADH dehydrogenase subunit N A1E_02335 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism