Parvibaculum lavamentivorans DS-1, complete genome NC_009719 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 154251762 Common - protein of unknown function DUF971 Plav_1309 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 154251247 Common - cation diffusion facilitator family transporter Plav_0791 214 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 154253382 Common - plasmid maintenance system antidote protein, XRE family Plav_2942 64 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 154253444 Common - type I secretion outer membrane protein, TolC family Plav_3004 144 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154252863 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Plav_2421 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 154252104 Common - beta-lactamase domain protein Plav_1652 84 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154251342 Common - FAD dependent oxidoreductase Plav_0886 94 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 154252531 Common - AMP-dependent synthetase and ligase Plav_2084 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154252563 Common - Holliday junction DNA helicase RuvA Plav_2116 207 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 154251765 Common - thioredoxin Plav_1312 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 154250648 Common - RNA polymerase, sigma 54 subunit, RpoN Plav_0192 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 154253196 Common - ribosomal protein L15 Plav_2755 171 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 154252624 Common - protein of unknown function DUF520 Plav_2177 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 154251212 Common - hypothetical protein Plav_0756 13 None None None 154253834 Common - hypothetical protein Plav_3398 14 None None None 154250614 Common - short-chain dehydrogenase/reductase SDR Plav_0158 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252942 Common - hypothetical protein Plav_2500 12 None None None 154251259 Nonpathogen - hypothetical protein Plav_0803 1 None None None 154252684 Common - Polynucleotide adenylyltransferase region Plav_2237 186 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 154250996 Common - alpha amylase catalytic region Plav_0540 92 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 154253028 Common - phosphoribosylformylglycinamidine synthase I Plav_2587 230 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 154251204 Common - glycine cleavage T protein (aminomethyl transferase) Plav_0748 107 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 154253260 Common - aromatic amino acid beta-eliminating lyase/threonine aldolase Plav_2819 79 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 154253595 Common - CTP synthase Plav_3156 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 154253638 Nonpathogen - hypothetical protein Plav_3199 1 None None None 154252212 Common - short-chain dehydrogenase/reductase SDR Plav_1760 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252795 Nonpathogen - hypothetical protein Plav_2350 4 None None None 154252558 Common - 5-formyltetrahydrofolate cyclo-ligase Plav_2111 78 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 154251293 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Plav_0837 138 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 154253863 Common - protein of unknown function DUF1525 Plav_3427 17 None None None 154252086 Common - Ubiquinone biosynthesis protein COQ7 Plav_1634 45 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 154251592 Common - Limonene-12-epoxide hydrolase Plav_1138 9 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 154253707 Common - hypothetical protein Plav_3269 36 COG3164 COG3164, Predicted membrane protein Function unknown 154250751 Nonpathogen - hypothetical protein Plav_0295 14 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 154251181 Common - peptidase S49 Plav_0725 187 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154250571 Common - Phosphotransferase system, phosphocarrier protein HPr Plav_0115 106 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 154252207 Common - Resolvase domain Plav_1755 91 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 154251480 Common - AMP-dependent synthetase and ligase Plav_1025 216 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251807 Common - Homospermidine synthase Plav_1354 26 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 154252304 Common - 2,3-diketo-5-methylthio-1-phosphopentane phosphatase Plav_1854 31 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 154253431 Common - NUDIX hydrolase Plav_2991 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 154252071 Common - regulatory protein ArsR Plav_1619 128 COG0640 ArsR, Predicted transcriptional regulators Transcription 154253975 Common - AAA ATPase Plav_3544 69 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 154251608 Common - acetoacetyl-CoA synthase Plav_1154 207 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154250559 Common - protein of unknown function DUF1457 Plav_0103 10 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252592 Common - inner membrane protein Plav_2145 24 COG3686 COG3686, Predicted membrane protein Function unknown 154250675 Common - ribosomal protein L20 Plav_0219 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 154251512 Common - protein of unknown function DUF1289 Plav_1057 36 COG3313 COG3313, Predicted Fe-S protein General function prediction only 154251934 Common - GCN5-related N-acetyltransferase Plav_1481 96 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 154254075 Common - DNA-binding protein Plav_3644 40 COG2944 COG2944, Predicted transcriptional regulator Transcription 154251305 Common - Enoyl-CoA hydratase/isomerase Plav_0849 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253677 Common - hypothetical protein Plav_3239 12 None None None 154252286 Common - Conjugal transfer protein TrbC Plav_1836 23 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 154253923 Common - PAS/PAC sensor hybrid histidine kinase Plav_3491 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154251987 Common - acriflavin resistance protein Plav_1535 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154253462 Common - arginyl-tRNA synthetase Plav_3022 247 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154250747 Common - peptidase M16 domain protein Plav_0291 175 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 154251962 Common - hypothetical protein Plav_1510 15 None None None 154250736 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_0280 30 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154252159 Nonpathogen - hypothetical protein Plav_1707 1 COG1738 COG1738, Uncharacterized conserved protein Function unknown 154250581 Nonpathogen - hypothetical protein Plav_0125 1 None None None 154253060 Common - short-chain dehydrogenase/reductase SDR Plav_2619 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253090 Common - hypothetical protein Plav_2649 31 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 154250958 Common - glutamine amidotransferase class-I Plav_0502 125 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 154252857 Common - Peptidoglycan glycosyltransferase Plav_2415 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 154254081 Common - DSBA oxidoreductase Plav_3650 47 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 154250548 Common - aldehyde dehydrogenase Plav_0092 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154252601 Common - phospholipase D/Transphosphatidylase Plav_2154 146 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 154252781 Common - hypothetical protein Plav_2336 5 None None None 154253931 Common - cytochrome P450 Plav_3499 85 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154252836 Common - helix-turn-helix- domain containing protein AraC type Plav_2393 63 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154253069 Common - hypothetical protein Plav_2628 21 None None None 154251980 Common - Cytochrome c oxidase cbb3 type accessory protein FixG Plav_1528 80 COG0348 NapH, Polyferredoxin Energy production and conversion 154252447 Common - acriflavin resistance protein Plav_2000 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154253174 Common - translation elongation factor G Plav_2733 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 154250805 Nonpathogen - hypothetical protein Plav_0349 6 None None None 154250515 Nonpathogen - hypothetical protein Plav_0059 1 None None None 154253315 Common - GTP-binding protein Era Plav_2875 231 COG1159 Era, GTPase General function prediction only 154252899 Common - protein of unknown function DUF59 Plav_2457 233 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154251470 Common - potassium-transporting ATPase, A subunit Plav_1014 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 154252957 Common - ABC-type uncharacterized transport system auxiliary component-like protein Plav_2515 17 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 154253007 Nonpathogen - hypothetical protein Plav_2565 8 None None None 154252136 Common - OmpA domain protein transmembrane region-containing protein Plav_1684 7 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 154250846 Common - Integral membrane protein TerC Plav_0390 98 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 154251451 Common - TonB family protein Plav_0995 46 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154253071 Nonpathogen - hypothetical protein Plav_2630 1 None None None 154253620 Common - citrate synthase I Plav_3181 193 COG0372 GltA, Citrate synthase Energy production and conversion 154253350 Common - riboflavin biosynthesis protein RibD Plav_2910 225 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 154250642 Nonpathogen - hypothetical protein Plav_0186 1 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 154252294 Common - hypothetical protein Plav_1844 22 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 154253625 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Plav_3186 194 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 154253021 Common - alanyl-tRNA synthetase Plav_2579 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154251015 Common - short-chain dehydrogenase/reductase SDR Plav_0559 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154250500 Common - Ada metal-binding domain protein Plav_0044 124 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 154250685 Common - cyclic nucleotide-binding protein Plav_0229 17 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154251538 Common - patatin Plav_1083 14 None None None 154253155 Common - short-chain dehydrogenase/reductase SDR Plav_2714 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154253234 Common - aldehyde dehydrogenase Plav_2793 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154253615 Common - molybdenum cofactor biosynthesis protein C Plav_3176 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 154251385 Common - integral membrane sensor signal transduction histidine kinase Plav_0929 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154251055 Common - Histidine--tRNA ligase Plav_0599 221 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 154250828 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_0372 192 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 154252414 Common - Threonine aldolase Plav_1966 69 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 154253799 Common - ribosomal protein S18 Plav_3362 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 154252611 Common - pseudouridine synthase, RluA family Plav_2164 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 154253099 Nonpathogen - YCII-related Plav_2658 1 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 154252636 Common - Phosphatidylethanolamine N-methyltransferase Plav_2189 119 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154253015 Common - flagellar biosynthetic protein FliQ Plav_2573 27 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 154252813 Common - hypothetical protein Plav_2370 5 None None None 154253778 Common - SurA domain Plav_3341 133 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 154252650 Common - protein of unknown function DUF1007 Plav_2203 33 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 154252750 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Plav_2303 146 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 154252729 Common - hypothetical protein Plav_2282 11 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 154251752 Common - outer membrane lipoprotein carrier protein LolA Plav_1299 39 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 154251854 Common - protein of unknown function DUF1223 Plav_1401 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 154252673 Common - GCN5-related N-acetyltransferase Plav_2226 82 COG3153 COG3153, Predicted acetyltransferase General function prediction only 154251823 Common - protein of unknown function YGGT Plav_1370 34 None None None 154252676 Common - ABC transporter related Plav_2229 248 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 154251009 Common - ABC transporter related Plav_0553 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 154253586 Common - transcriptional regulator, PadR-like family Plav_3146 25 COG1695 COG1695, Predicted transcriptional regulators Transcription 154251116 Common - transcriptional regulator, AbrB family Plav_0660 10 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 154251262 Common - Pyridoxal-dependent decarboxylase Plav_0806 104 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 154251780 Common - peptidase M48 Ste24p Plav_1327 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 154251976 Common - integral membrane-like protein Plav_1524 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 154251697 Common - transcriptional regulator, LysR family Plav_1244 169 COG0583 LysR, Transcriptional regulator Transcription 154253083 Common - Enoyl-CoA hydratase/isomerase Plav_2642 75 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154251888 Common - succinate dehydrogenase, flavoprotein subunit Plav_1435 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154253935 Common - 3-demethylubiquinone-9 3-methyltransferase Plav_3503 66 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 154253113 Common - hypothetical protein Plav_2672 5 None None None 154253303 Common - SsrA-binding protein Plav_2863 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 154251664 Common - protein of unknown function DUF736 Plav_1211 27 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154251569 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Plav_1115 141 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 154251583 Common - Poly-beta-hydroxybutyrate polymerase domain protein Plav_1129 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154253873 Common - IstB domain protein ATP-binding protein Plav_3437 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 154251491 Common - aldehyde dehydrogenase Plav_1036 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154252934 Common - hypothetical protein Plav_2492 11 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 154251737 Common - thiamine monophosphate synthase Plav_1284 14 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 154253055 Common - amidohydrolase Plav_2614 158 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 154253568 Common - multi-sensor signal transduction histidine kinase Plav_3128 214 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 154253540 Common - transferase hexapeptide repeat containing protein Plav_3100 217 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 154253053 Common - alpha/beta hydrolase fold Plav_2612 149 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253700 Common - FeS assembly protein SufB Plav_3262 185 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 154251177 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Plav_0721 180 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 154250938 Common - hypothetical protein Plav_0482 3 None None None 154253299 Common - Na+/Picotransporter Plav_2859 83 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 154251886 Common - Succinate dehydrogenase cytochrome b556 subunit Plav_1433 49 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 154250890 Common - hypothetical protein Plav_0434 9 None None None 154251549 Common - glutathione-disulfide reductase Plav_1095 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154252788 Common - protein of unknown function DUF45 Plav_2343 151 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 154251580 Common - hypothetical protein Plav_1126 6 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253825 Common - putative transcriptional regulator, MerR family Plav_3389 127 COG0789 SoxR, Predicted transcriptional regulators Transcription 154252375 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Plav_1927 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 154251708 Common - maf protein Plav_1255 55 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 154252337 Common - ABC transporter related Plav_1889 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 154254088 Common - 2-polyprenylphenol 6-hydroxylase Plav_3657 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 154253749 Common - WbqC-like family protein Plav_3312 40 None None None 154251527 Common - protein of unknown function DUF1428 Plav_1072 38 COG5507 COG5507, Uncharacterized conserved protein Function unknown 154251733 Common - leucyl-tRNA synthetase Plav_1280 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154250467 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_0011 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 154253853 Common - hypothetical protein Plav_3417 10 None None None 154252313 Common - protein of unknown function DUF519 Plav_1863 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 154252248 Common - Alpha/beta hydrolase fold-3 domain protein Plav_1797 122 COG0657 Aes, Esterase/lipase Lipid metabolism 154251063 Common - protein of unknown function DUF72 Plav_0607 90 COG1801 COG1801, Uncharacterized conserved protein Function unknown 154251810 Common - L-carnitine dehydratase/bile acid-inducible protein F Plav_1357 79 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 154253346 Nonpathogen - hypothetical protein Plav_2906 2 None None None 154250716 Common - protein of unknown function DUF195 Plav_0260 143 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 154252038 Common - ChaC family protein Plav_1586 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 154251679 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein Plav_1226 86 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 154251551 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1097 163 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 154253302 Common - dihydrodipicolinate synthase Plav_2862 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 154251622 Common - inosine-5'-monophosphate dehydrogenase Plav_1168 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 154252151 Common - acyl-CoA dehydrogenase domain protein Plav_1699 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251315 Nonpathogen - hypothetical protein Plav_0859 1 None None None 154250916 Common - SCP-like extracellular Plav_0460 17 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 154252737 Nonpathogen - hypothetical protein Plav_2290 1 None None None 154252413 Nonpathogen - hypothetical protein Plav_1965 1 None None None 154252330 Common - phospholipase D/Transphosphatidylase Plav_1882 152 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 154254064 Common - hypothetical protein Plav_3633 5 None None None 154252232 Common - cyclohexanone monooxygenase Plav_1781 74 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154250914 Common - Peptidoglycan-binding domain 1 protein Plav_0458 105 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154253428 Common - GCN5-related N-acetyltransferase Plav_2988 31 COG0456 RimI, Acetyltransferases General function prediction only 154253267 Common - NUDIX hydrolase Plav_2827 40 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 154251759 Common - Pyrrolo-quinoline quinone Plav_1306 70 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 154253292 Common - alpha/beta hydrolase fold Plav_2852 66 COG2267 PldB, Lysophospholipase Lipid metabolism 154253131 Common - globin Plav_2690 47 COG2346 COG2346, Truncated hemoglobins General function prediction only 154252272 Common - Exodeoxyribonuclease I Plav_1822 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 154250990 Common - tartrate dehydrogenase Plav_0534 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 154252135 Common - thioesterase superfamily protein Plav_1683 14 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251629 Common - PglZ domain protein Plav_1175 15 None None None 154252487 Common - response regulator receiver protein Plav_2040 203 COG4566 TtrR, Response regulator Signal transduction mechanisms 154251716 Common - glutathione-dependent formaldehyde-activating GFA Plav_1263 50 COG3791 COG3791, Uncharacterized conserved protein Function unknown 154252365 Common - glycosyl transferase family 2 Plav_1917 185 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 154253768 Common - phosphoribosylformylglycinamidine cyclo-ligase Plav_3331 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 154251372 Common - hypothetical protein Plav_0916 26 COG5448 COG5448, Uncharacterized conserved protein Function unknown 154251004 Common - short-chain dehydrogenase/reductase SDR Plav_0548 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251135 Common - GCN5-related N-acetyltransferase Plav_0679 129 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 154250721 Nonpathogen - hypothetical protein Plav_0265 5 None None None 154250813 Common - integrase family protein Plav_0357 134 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154253661 Common - NADH-quinone oxidoreductase, E subunit Plav_3222 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 154252440 Common - metallophosphoesterase Plav_1993 61 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 154253228 Nonpathogen - hypothetical protein Plav_2787 1 None None None 154253389 Nonpathogen - hypothetical protein Plav_2949 1 None None None 154250651 Common - protein of unknown function DUF1239 Plav_0195 28 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 154252645 Common - protein of unknown function DUF323 Plav_2198 92 COG1262 COG1262, Uncharacterized conserved protein Function unknown 154251493 Common - L-carnitine dehydratase/bile acid-inducible protein F Plav_1038 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 154252323 Common - addiction module antitoxin, RelB/DinJ family Plav_1874 34 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 154250560 Common - ABC transporter related Plav_0104 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154250830 Common - TonB system transport protein ExbD type-1 Plav_0374 119 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154252766 Nonpathogen - hypothetical protein Plav_2319 1 None None None 154253903 Nonpathogen - hypothetical protein Plav_3471 4 None None None 154250797 Nonpathogen - hypothetical protein Plav_0341 2 None None None 154251789 Common - protein of unknown function DUF1330 Plav_1336 13 COG5470 COG5470, Uncharacterized conserved protein Function unknown 154253898 Common - integrase family protein Plav_3466 106 COG0582 XerC, Integrase DNA replication, recombination, and repair 154253512 Common - hypothetical protein Plav_3072 4 None None None 154250839 Common - protein of unknown function DUF490 Plav_0383 72 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 154251674 Common - hypothetical protein Plav_1221 9 None None None 154252107 Nonpathogen - hypothetical protein Plav_1655 1 None None None 154252529 Nonpathogen - protein of unknown function DUF465 Plav_2082 1 COG5570 COG5570, Uncharacterized small protein Function unknown 154252350 Common - metallophosphoesterase Plav_1902 85 None None None 154251284 Common - Taurine dioxygenase Plav_0828 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154250633 Common - binding-protein-dependent transport systems inner membrane component Plav_0177 164 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 154253490 Common - pantetheine-phosphate adenylyltransferase Plav_3050 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 154252579 Common - phosphomethylpyrimidine kinase Plav_2132 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 154253004 Common - flagellar basal body rod protein Plav_2562 123 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 154252197 Common - hypothetical protein Plav_1745 32 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 154253860 Common - hypothetical protein Plav_3424 30 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 154250885 Common - hypothetical protein Plav_0429 15 None None None 154252732 Common - hypothetical protein Plav_2285 20 COG3791 COG3791, Uncharacterized conserved protein Function unknown 154251250 Common - prophage CP4-57 regulatory Plav_0794 13 None None None 154251946 Common - thioesterase superfamily protein Plav_1494 57 COG0824 FcbC, Predicted thioesterase General function prediction only 154252999 Nonpathogen - hypothetical protein Plav_2557 5 None None None 154250949 Nonpathogen - hypothetical protein Plav_0493 1 None None None 154253570 Common - signal transduction histidine kinase, nitrogen specific, NtrB Plav_3130 219 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 154251699 Common - Smr protein/MutS2 Plav_1246 89 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 154251309 Common - flavin-binding family monooxygenase Plav_0853 65 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154253160 Nonpathogen - hypothetical protein Plav_2719 1 None None None 154253367 Common - cytochrome oxidase assembly Plav_2927 53 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 154252892 Common - PEP2-like protein Plav_2450 11 None None None 154250972 Common - YhhN family protein Plav_0516 26 COG3714 COG3714, Predicted membrane protein Function unknown 154251958 Common - 3-beta hydroxysteroid dehydrogenase/isomerase Plav_1506 140 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154251871 Common - signal recognition particle protein Plav_1418 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 154252583 Common - protein of unknown function DUF6 transmembrane Plav_2136 75 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 154251286 Common - protein of unknown function DUF6 transmembrane Plav_0830 28 None None None 154252818 Common - thiamine pyrophosphate protein domain protein TPP-binding Plav_2375 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 154251447 Common - luciferase family protein Plav_0991 84 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154252425 Nonpathogen - hypothetical protein Plav_1978 1 None None None 154252004 Common - methionine aminopeptidase, type I Plav_1552 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 154251999 Common - putative transcriptional regulator, MerR family Plav_1547 33 COG0789 SoxR, Predicted transcriptional regulators Transcription 154253559 Common - beta-lactamase domain protein Plav_3119 213 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154251644 Common - P-type conjugative transfer protein TrbJ Plav_1190 22 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 154252739 Common - transcriptional regulator, TetR family Plav_2292 113 COG1309 AcrR, Transcriptional regulator Transcription 154251133 Common - threonine synthase Plav_0677 142 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 154252485 Common - GCN5-related N-acetyltransferase Plav_2038 5 COG0456 RimI, Acetyltransferases General function prediction only 154250738 Common - transcriptional regulator, MarR family Plav_0282 13 COG1846 MarR, Transcriptional regulators Transcription 154250744 Common - lipoprotein signal peptidase Plav_0288 98 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154251401 Common - integral membrane sensor signal transduction histidine kinase Plav_0945 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154251800 Common - Alpha/beta hydrolase fold-3 domain protein Plav_1347 126 COG0657 Aes, Esterase/lipase Lipid metabolism 154253013 Common - flagellar basal-body rod protein FlgC Plav_2571 122 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 154250525 Common - SAF domain protein Plav_0069 39 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 154252016 Common - para-aminobenzoate synthase, subunit I Plav_1564 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 154253550 Common - dTMP kinase Plav_3110 226 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 154254014 Common - maleylacetoacetate isomerase Plav_3583 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253414 Common - putative cold-shock DNA-binding domain protein Plav_2974 163 COG1278 CspC, Cold shock proteins Transcription 154253215 Common - lipoate-protein ligase B Plav_2774 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 154250609 Common - transcriptional regulator, TetR family Plav_0153 40 COG1309 AcrR, Transcriptional regulator Transcription 154252394 Common - acyltransferase 3 Plav_1946 85 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 154250854 Common - phosphate uptake regulator, PhoU Plav_0398 203 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 154252507 Common - NAD(P)(+) transhydrogenase (AB-specific) Plav_2060 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 154250619 Common - protein of unknown function DUF1329 Plav_0163 19 None None None 154252237 Common - aldehyde dehydrogenase Plav_1786 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154252525 Common - transcriptional regulator, BadM/Rrf2 family Plav_2078 175 COG1959 COG1959, Predicted transcriptional regulator Transcription 154251724 Nonpathogen - hypothetical protein Plav_1271 13 None None None 154250538 Common - cytochrome P450 Plav_0082 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154253896 Common - transcriptional regulator, XRE family Plav_3463 13 COG1396 HipB, Predicted transcriptional regulators Transcription 154253524 Nonpathogen - hypothetical protein Plav_3084 1 None None None 154251817 Common - BNR/Asp-box repeat protein Plav_1364 43 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 154250490 Common - hypothetical protein Plav_0034 7 None None None 154250531 Common - Tetratricopeptide TPR_2 repeat protein Plav_0075 11 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 154253579 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase Plav_3139 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 154252559 Common - metallophosphoesterase Plav_2112 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 154251393 Common - Glutaryl-7-aminocephalosporanic-acid acylase Plav_0937 78 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 154253959 Common - hypothetical protein Plav_3527 13 None None None 154253960 Common - hypothetical protein Plav_3529 10 COG5419 COG5419, Uncharacterized conserved protein Function unknown 154253584 Common - extracellular solute-binding protein family 5 Plav_3144 139 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 154252376 Common - hypothetical protein Plav_1928 20 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 154252984 Common - protein of unknown function DUF1078 domain protein Plav_2542 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 154251275 Common - hypothetical protein Plav_0819 11 COG5379 BtaA, S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase Lipid metabolism 154252881 Common - D-lactate dehydrogenase (cytochrome) Plav_2439 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 154252438 Common - hypothetical protein Plav_1991 25 None None None 154252216 Common - hypothetical protein Plav_1764 36 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154250872 Common - short-chain dehydrogenase/reductase SDR Plav_0416 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251860 Nonpathogen - Heme exporter protein D (CcmD) Plav_1407 1 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 154252622 Common - flagellar protein export ATPase FliI Plav_2175 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 154251900 Common - Arylamine N-acetyltransferase Plav_1447 44 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 154252180 Common - Epoxide hydrolase domain protein Plav_1728 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251076 Common - exodeoxyribonuclease VII, large subunit Plav_0620 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 154252989 Common - short-chain dehydrogenase/reductase SDR Plav_2547 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253241 Common - NHL repeat containing protein Plav_2800 25 COG3391 COG3391, Uncharacterized conserved protein Function unknown 154252432 Nonpathogen - hypothetical protein Plav_1985 4 None None None 154253351 Common - riboflavin synthase, alpha subunit Plav_2911 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 154252705 Common - ribose-phosphate pyrophosphokinase Plav_2258 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 154250474 Common - two component transcriptional regulator, Fis family Plav_0018 218 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 154251878 Common - 3-isopropylmalate dehydrogenase Plav_1425 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 154253088 Common - hypothetical protein Plav_2647 26 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 154251990 Common - transcriptional regulator, TetR family Plav_1538 84 COG1309 AcrR, Transcriptional regulator Transcription 154251370 Nonpathogen - phage conserved hypothetical protein Plav_0914 4 None None None 154253374 Common - CoA-binding domain protein Plav_2934 137 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 154250659 Nonpathogen - hypothetical protein Plav_0203 5 None None None 154253497 Common - glutathione-dependent formaldehyde-activating GFA Plav_3057 70 COG3791 COG3791, Uncharacterized conserved protein Function unknown 154252842 Common - Methyltransferase type 11 Plav_2400 190 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252145 Common - RNA polymerase, sigma 32 subunit, RpoH Plav_1693 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 154252031 Common - Methyltransferase type 11 Plav_1579 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154251653 Common - protein of unknown function DUF736 Plav_1199 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154253630 Common - phosphatidate cytidylyltransferase Plav_3191 207 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 154253313 Common - signal peptidase I Plav_2873 204 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 154251896 Common - protein tyrosine phosphatase Plav_1443 121 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 154253713 Common - peptide chain release factor 2 Plav_3275 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 154253504 Common - sulfate adenylyltransferase, large subunit Plav_3064 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 154252692 Common - methylthioadenosine phosphorylase Plav_2245 147 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 154252165 Common - cobalt chelatase, pCobS small subunit Plav_1713 61 COG0714 COG0714, MoxR-like ATPases General function prediction only 154252721 Common - molybdopterin converting factor, subunit 1 Plav_2274 47 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 154251264 Common - TonB-dependent receptor Plav_0808 93 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154251613 Nonpathogen - hypothetical protein Plav_1159 5 None None None 154253081 Common - Enoyl-CoA hydratase/isomerase Plav_2640 182 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252281 Common - hypothetical protein Plav_1831 24 COG3673 COG3673, Uncharacterized conserved protein Function unknown 154253450 Common - dihydroxy-acid dehydratase Plav_3010 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 154251051 Common - cytochrome d ubiquinol oxidase, subunit II Plav_0595 149 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 154254026 Common - PAS/PAC sensor hybrid histidine kinase Plav_3595 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253203 Common - protease Do Plav_2762 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 154252228 Common - alpha/beta hydrolase fold Plav_1777 125 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251426 Common - transcriptional regulator, BadM/Rrf2 family Plav_0970 60 COG1959 COG1959, Predicted transcriptional regulator Transcription 154253816 Common - hypothetical protein Plav_3379 23 None None None 154251979 Common - FixH family protein Plav_1527 24 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 154252188 Common - phosphoribosyltransferase Plav_1736 170 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 154252312 Common - major facilitator superfamily MFS_1 Plav_1862 28 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 154253723 Common - membrane protein-like protein Plav_3285 64 COG2323 COG2323, Predicted membrane protein Function unknown 154253818 Common - hypothetical protein Plav_3381 21 None None None 154250483 Common - putative exporter of RND superfamily Plav_0027 58 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 154251552 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1098 136 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 154252456 Common - hypothetical protein Plav_2009 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253275 Common - dihydroorotase, multifunctional complex type Plav_2835 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 154252965 Common - ferredoxin Plav_2523 43 COG0633 Fdx, Ferredoxin Energy production and conversion 154251856 Common - Enoyl-CoA hydratase/isomerase Plav_1403 172 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154254072 Common - sulfatase Plav_3641 77 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154254029 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase Plav_3598 217 COG0281 SfcA, Malic enzyme Energy production and conversion 154251926 Common - peptidase M23B Plav_1473 105 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 154252257 Common - acyl-CoA dehydrogenase domain protein Plav_1806 133 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154250969 Common - Deoxyribodipyrimidine photo-lyase Plav_0513 144 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 154253534 Common - Invasion associated locus B family protein Plav_3094 17 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 154252915 Common - nitroreductase Plav_2473 48 COG0778 NfnB, Nitroreductase Energy production and conversion 154252266 Common - parB-like partition protein Plav_1816 154 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154252176 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Plav_1724 192 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 154253530 Common - AMP-dependent synthetase and ligase Plav_3090 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252175 Nonpathogen - hypothetical protein Plav_1723 3 None None None 154251335 Nonpathogen - hypothetical protein Plav_0879 4 None None None 154252748 Common - peptidase M48 Ste24p Plav_2301 131 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 154251082 Common - protein of unknown function DUF374 Plav_0626 44 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 154250691 Common - response regulator receiver protein Plav_0235 74 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 154252471 Common - signal transduction histidine kinase Plav_2024 122 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 154251160 Common - alpha/beta hydrolase fold Plav_0704 167 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154254048 Common - RNA modification enzyme, MiaB family Plav_3617 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 154253044 Common - choline/carnitine/betaine transporter Plav_2603 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 154252712 Common - pyrroline-5-carboxylate reductase Plav_2265 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 154252717 Common - transcriptional regulator, MarR family Plav_2270 58 COG1846 MarR, Transcriptional regulators Transcription 154252353 Common - hypothetical protein Plav_1905 28 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 154253918 Common - Colicin V production protein Plav_3486 50 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 154251459 Common - type I secretion membrane fusion protein, HlyD family Plav_1003 141 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154252908 Common - ketol-acid reductoisomerase Plav_2466 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 154253031 Common - protein of unknown function DUF1476 Plav_2590 25 COG5467 COG5467, Uncharacterized conserved protein Function unknown 154251577 Common - Enoyl-CoA hydratase/isomerase Plav_1123 172 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154250874 Common - hypothetical protein Plav_0418 17 None None None 154253981 Common - conjugation TrbI family protein Plav_3550 57 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 154251840 Common - short-chain dehydrogenase/reductase SDR Plav_1387 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251809 Common - nitrogen regulatory protein P-II Plav_1356 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 154253973 Common - Conjugal transfer protein TrbC Plav_3542 23 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 154253523 Common - short-chain dehydrogenase/reductase SDR Plav_3083 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154250778 Nonpathogen - helix-turn-helix domain protein Plav_0322 1 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 154252973 Common - DNA polymerase III, alpha subunit Plav_2531 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 154251089 Common - Appr-1-p processing domain protein Plav_0633 112 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 154252828 Common - DoxX family protein Plav_2385 71 COG2259 COG2259, Predicted membrane protein Function unknown 154253067 Nonpathogen - hypothetical protein Plav_2626 1 None None None 154250557 Nonpathogen - hypothetical protein Plav_0101 1 None None None 154251050 Common - protein of unknown function DUF955 Plav_0594 47 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 154252052 Common - diaminopimelate decarboxylase Plav_1600 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 154252061 Common - ATP--cobalamin adenosyltransferase Plav_1609 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 154252518 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Plav_2071 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 154253489 Common - DNA gyrase, A subunit Plav_3049 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 154253836 Common - hypothetical protein Plav_3400 13 None None None 154251635 Common - hypothetical protein Plav_1181 5 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 154251705 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_1252 46 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 154250807 Common - beta-lactamase domain protein Plav_0351 132 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 154250508 Common - response regulator receiver protein Plav_0052 94 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154252638 Nonpathogen - hypothetical protein Plav_2191 1 None None None 154253328 Common - flavin reductase domain protein FMN-binding Plav_2888 127 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 154252916 Common - phosphoribosylglycinamide formyltransferase 2 Plav_2474 196 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 154250513 Nonpathogen - Entericidin EcnAB Plav_0057 1 COG5510 COG5510, Predicted small secreted protein Function unknown 154251431 Common - Lytic transglycosylase catalytic Plav_0975 105 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 154252349 Common - KpsF/GutQ family protein Plav_1901 176 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 154250771 Common - ParB domain protein nuclease Plav_0315 62 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154252385 Common - glycoside hydrolase family 4 Plav_1937 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 154251601 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1147 129 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 154253845 Common - hypothetical protein Plav_3409 19 None None None 154250960 Common - ribonucleoside-diphosphate reductase, alpha subunit Plav_0504 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 154254035 Common - integral membrane protein MviN Plav_3604 196 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 154253127 Common - response regulator receiver protein Plav_2686 159 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 154253109 Common - threonyl-tRNA synthetase Plav_2668 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154250625 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Plav_0169 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 154252890 Common - Thymidylate synthase Plav_2448 142 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 154251236 Common - Polyprenyl synthetase Plav_0780 235 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 154253557 Nonpathogen - hypothetical protein Plav_3117 1 None None None 154253941 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein Plav_3509 86 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 154250703 Common - binding-protein-dependent transport systems inner membrane component Plav_0247 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 154253988 Common - hypothetical protein Plav_3557 7 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 154251687 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Plav_1234 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 154251484 Common - AMP-dependent synthetase and ligase Plav_1029 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251682 Common - pantothenate kinase Plav_1229 80 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 154251183 Common - glycyl-tRNA synthetase, alpha subunit Plav_0727 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 154252778 Nonpathogen - hypothetical protein Plav_2331 1 None None None 154250634 Common - ABC transporter related Plav_0178 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 154251229 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_0773 9 None None None 154251222 Common - ferric uptake regulator, Fur family Plav_0766 123 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154252210 Common - protein of unknown function DUF35 Plav_1758 54 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 154250584 Common - 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway)-like protein Plav_0128 36 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 154253254 Common - hypothetical protein Plav_2813 24 None None None 154253252 Common - ROK family protein Plav_2811 138 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 154253656 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Plav_3217 74 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 154251786 Common - hypothetical protein Plav_1333 14 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 154253407 Common - NADH dehydrogenase (quinone) Plav_2967 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 154252128 Common - ThiJ/PfpI domain protein Plav_1676 92 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 154251409 Nonpathogen - hypothetical protein Plav_0953 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 154251907 Common - 2-oxoglutarate dehydrogenase, E1 subunit Plav_1454 149 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 154251463 Common - hypothetical protein Plav_1007 19 COG5615 COG5615, Predicted integral membrane protein Function unknown 154252499 Common - oligoendopeptidase, pepF/M3 family Plav_2052 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 154251506 Common - protein of unknown function DUF81 Plav_1051 107 COG0730 COG0730, Predicted permeases General function prediction only 154251152 Common - H+transporting two-sector ATPase C subunit Plav_0696 59 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 154250907 Common - hypothetical protein Plav_0451 15 None None None 154251744 Common - cyclic nucleotide-binding protein Plav_1291 55 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154252403 Common - ATPase associated with various cellular activities AAA_5 Plav_1955 92 COG0714 COG0714, MoxR-like ATPases General function prediction only 154250793 Nonpathogen - hypothetical protein Plav_0337 1 None None None 154251477 Common - Amidohydrolase 3 Plav_1022 80 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 154252831 Common - Activator of Hsp90 ATPase 1 family protein Plav_2388 45 COG3832 COG3832, Uncharacterized conserved protein Function unknown 154253134 Common - NADH:flavin oxidoreductase/NADH oxidase Plav_2693 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 154251351 Common - protein of unknown function DUF1214 Plav_0895 38 COG5402 COG5402, Uncharacterized conserved protein Function unknown 154250576 Nonpathogen - hypothetical protein Plav_0120 1 None None None 154252114 Common - protein of unknown function DUF924 Plav_1662 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 154252657 Nonpathogen - hypothetical protein Plav_2210 2 None None None 154251367 Common - phage major tail protein, TP901-1 family Plav_0911 19 COG5437 COG5437, Predicted secreted protein Function unknown 154250983 Common - maf protein Plav_0527 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 154253171 Common - DNA-directed RNA polymerase, beta' subunit Plav_2730 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 154252057 Nonpathogen - protein of unknown function DUF1457 Plav_1605 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154251358 Common - protein of unknown function DUF264 Plav_0902 26 COG5323 COG5323, Uncharacterized conserved protein Function unknown 154252600 Nonpathogen - hypothetical protein Plav_2153 1 None None None 154253502 Nonpathogen - hypothetical protein Plav_3062 1 None None None 154254083 Common - transcriptional regulator, HxlR family Plav_3652 94 COG1733 COG1733, Predicted transcriptional regulators Transcription 154253176 Common - ribosomal protein S10 Plav_2735 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 154251680 Nonpathogen - hypothetical protein Plav_1227 1 None None None 154252783 Common - hypothetical protein Plav_2338 10 None None None 154250895 Common - MATE efflux family protein Plav_0439 83 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 154252603 Common - peptide methionine sulfoxide reductase Plav_2156 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 154250803 Common - copper resistance B precursor Plav_0347 42 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 154253269 Common - protein of unknown function DUF983 Plav_2829 29 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 154253286 Common - Glutathione S-transferase domain Plav_2846 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252500 Common - ABC-1 domain protein Plav_2053 182 COG0661 AarF, Predicted unusual protein kinase General function prediction only 154251436 Common - PfkB domain protein Plav_0980 106 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 154253094 Common - Rhomboid family protein Plav_2653 114 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 154252468 Nonpathogen - hypothetical protein Plav_2021 1 None None None 154253984 Common - phage transcriptional regulator, AlpA Plav_3553 25 COG3311 AlpA, Predicted transcriptional regulator Transcription 154253433 Common - ATP-dependent DNA helicase RecQ Plav_2993 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 154252874 Common - DNA ligase, NAD-dependent Plav_2432 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 154250528 Common - type II secretion system protein E Plav_0072 227 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 154253933 Common - aspartate-semialdehyde dehydrogenase Plav_3501 230 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 154252838 Common - histidine kinase Plav_2396 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252761 Common - carbamoyl-phosphate synthase, small subunit Plav_2314 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 154253188 Common - ribosomal protein L24 Plav_2747 209 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 154253646 Nonpathogen - hypothetical protein Plav_3207 1 None None None 154251844 Common - aldo/keto reductase Plav_1391 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 154253689 Common - integral membrane sensor signal transduction histidine kinase Plav_3251 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253913 Common - integral membrane sensor signal transduction histidine kinase Plav_3481 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154251536 Common - Uracil-DNA glycosylase superfamily Plav_1081 59 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 154250844 Common - transcriptional regulator, TetR family Plav_0388 38 COG1309 AcrR, Transcriptional regulator Transcription 154252931 Nonpathogen - hypothetical protein Plav_2489 5 None None None 154251735 Nonpathogen - porin, gram-negative type Plav_1282 4 None None None 154253009 Nonpathogen - hypothetical protein Plav_2567 9 None None None 154252461 Common - sulfatase Plav_2014 91 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154251252 Nonpathogen - hypothetical protein Plav_0796 1 None None None 154253758 Common - Methyltransferase type 12 Plav_3321 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154253092 Common - HfaB protein Plav_2651 7 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 154253118 Common - Phytanoyl-CoA dioxygenase Plav_2677 17 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 154252251 Common - 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase Plav_1800 30 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154251317 Common - ABC-2 type transporter Plav_0861 175 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 154252254 Common - putative nonspecific lipid-transfer protein Plav_1803 92 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253476 Common - protein-export membrane protein SecD Plav_3036 219 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 154253627 Common - surface antigen (D15) Plav_3188 158 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 154252112 Common - AMP-dependent synthetase and ligase Plav_1660 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253153 Common - transcriptional regulator, TetR family Plav_2712 30 COG1309 AcrR, Transcriptional regulator Transcription 154251356 Common - phosphate transporter Plav_0900 133 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 154251249 Common - hypothetical protein Plav_0793 9 None None None 154253073 Nonpathogen - hypothetical protein Plav_2632 7 None None None 154251348 Common - ABC transporter related Plav_0892 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 154252703 Common - Aminoacyl-tRNA hydrolase Plav_2256 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 154253161 Common - hypothetical protein Plav_2720 14 None None None 154253797 Common - malonyl CoA-acyl carrier protein transacylase Plav_3360 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 154253033 Common - regulatory protein TetR Plav_2592 7 None None None 154250684 Common - hypothetical protein Plav_0228 20 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 154253921 Common - hypothetical protein Plav_3489 24 COG4538 COG4538, Uncharacterized conserved protein Function unknown 154252490 Nonpathogen - hypothetical protein Plav_2043 1 None None None 154253690 Common - DEAD/DEAH box helicase domain protein Plav_3252 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 154251382 Common - nitroreductase Plav_0926 75 COG0778 NfnB, Nitroreductase Energy production and conversion 154253294 Common - protein of unknown function UPF0126 Plav_2854 133 COG2860 COG2860, Predicted membrane protein Function unknown 154251057 Common - hypothetical protein Plav_0601 17 None None None 154251563 Nonpathogen - hypothetical protein Plav_1109 2 None None None 154253617 Common - SOS-response transcriptional repressor, LexA Plav_3178 170 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 154252689 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Plav_2242 105 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 154251445 Common - TonB-dependent receptor plug Plav_0989 67 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154252138 Nonpathogen - hypothetical protein Plav_1686 1 None None None 154252360 Common - sulfotransferase Plav_1912 18 None None None 154250888 Common - lysyl-tRNA synthetase Plav_0432 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 154253446 Common - valyl-tRNA synthetase Plav_3006 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154253597 Nonpathogen - putative exported protein of unknown function Plav_3158 4 None None None 154252655 Common - protein of unknown function UPF0191 Plav_2208 10 COG2717 COG2717, Predicted membrane protein Function unknown 154253338 Common - acyl-CoA dehydrogenase domain protein Plav_2898 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252565 Common - Pol-Pal system-associated acyl-CoA thioesterase Plav_2118 124 COG0824 FcbC, Predicted thioesterase General function prediction only 154253771 Common - ABC transporter related Plav_3334 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 154250605 Common - ribosomal protein S1 Plav_0149 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 154252121 Common - Alkylglycerone-phosphate synthase Plav_1669 185 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 154250745 Common - hypothetical protein Plav_0289 13 None None None 154252804 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Plav_2359 215 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 154252753 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Plav_2306 225 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154250994 Common - hypothetical protein Plav_0538 29 None None None 154251362 Common - phage major capsid protein, HK97 family Plav_0906 54 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 154252861 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Plav_2419 209 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 154251770 Common - major facilitator superfamily MFS_1 Plav_1317 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 154253115 Common - nitroreductase Plav_2674 94 COG0778 NfnB, Nitroreductase Energy production and conversion 154252682 Common - protein of unknown function DUF1285 Plav_2235 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 154253542 Common - Glutathione S-transferase domain Plav_3102 108 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154250641 Common - TonB-dependent hemoglobin/transferrin/lactoferrin family receptor Plav_0185 132 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154253599 Nonpathogen - hypothetical protein Plav_3160 4 None None None 154253964 Common - hypothetical protein Plav_3533 16 None None None 154251273 Common - ABC transporter related Plav_0817 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 154254090 Common - formamidopyrimidine-DNA glycosylase Plav_3659 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 154253636 Common - DNA polymerase III, alpha subunit Plav_3197 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 154250765 Common - glucokinase Plav_0309 90 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 154250811 Common - heavy metal efflux pump, CzcA family Plav_0355 178 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 154253709 Common - protein of unknown function DUF455 Plav_3271 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 154252194 Common - ubiquinone biosynthesis O-methyltransferase Plav_1742 131 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154251340 Common - hypothetical protein Plav_0884 26 None None None 154251195 Common - hypothetical protein Plav_0739 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 154252406 Common - hypothetical protein Plav_1958 14 None None None 154253590 Common - GTP cyclohydrolase I Plav_3151 128 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 154250677 Common - phenylalanyl-tRNA synthetase, beta subunit Plav_0221 228 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 154251002 Common - malto-oligosyltrehalose synthase Plav_0546 125 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 154252868 Common - cell division protein FtsA Plav_2426 181 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 154253262 Common - putative transcriptional regulator, AsnC family Plav_2822 133 COG1522 Lrp, Transcriptional regulators Transcription 154252963 Common - Chorismate mutase Plav_2521 42 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 154253075 Common - transferase hexapeptide repeat containing protein Plav_2634 193 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 154251938 Common - excinuclease ATPase-like protein Plav_1485 14 None None None 154252084 Common - phospholipase/Carboxylesterase Plav_1632 107 COG0400 COG0400, Predicted esterase General function prediction only 154251214 Common - 2-nitropropane dioxygenase NPD Plav_0758 140 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154251884 Nonpathogen - hypothetical protein Plav_1431 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252102 Common - hypothetical protein Plav_1650 13 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251307 Common - major facilitator superfamily MFS_1 Plav_0851 103 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154252048 Common - MJ0042 family finger-like protein Plav_1596 16 None None None 154251295 Common - protein of unknown function DUF1214 Plav_0839 41 COG5402 COG5402, Uncharacterized conserved protein Function unknown 154253026 Common - BolA family protein Plav_2585 88 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 154250671 Common - hypothetical protein Plav_0215 17 None None None 154251964 Nonpathogen - hypothetical protein Plav_1512 1 None None None 154254036 Common - integral membrane sensor hybrid histidine kinase Plav_3605 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253675 Common - Phosphoglycerate mutase Plav_3237 10 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 154251179 Common - hypothetical protein Plav_0723 23 None None None 154253357 Common - sodium/hydrogen exchanger Plav_2917 162 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 154253827 Common - lipoprotein signal peptidase Plav_3391 180 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154252388 Common - protein of unknown function DUF404 Plav_1940 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 154251603 Common - Hydantoinase/oxoprolinase Plav_1149 108 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154250964 Common - Glutathione S-transferase domain Plav_0508 106 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251694 Common - putative ABC transporter, substrate-binding protein Plav_1241 69 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 154251105 Common - aminoglycoside phosphotransferase Plav_0649 63 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 154250734 Common - aminotransferase class-III Plav_0278 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 154252598 Common - Uracil-DNA glycosylase superfamily Plav_2151 28 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 154253145 Common - glycerol kinase Plav_2704 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 154250924 Common - transcriptional regulator, AraC family Plav_0468 143 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 154252209 Common - acetyl-CoA acetyltransferase Plav_1757 91 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154251461 Common - hypothetical protein Plav_1005 16 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 154251985 Nonpathogen - hypothetical protein Plav_1533 1 None None None 154252533 Common - transcriptional regulator, MarR family Plav_2086 43 COG1846 MarR, Transcriptional regulators Transcription 154250678 Common - Enoyl-CoA hydratase/isomerase Plav_0222 172 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252284 Common - CopG domain protein DNA-binding domain protein Plav_1834 23 None None None 154252631 Common - flagellar M-ring protein FliF Plav_2184 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 154250795 Nonpathogen - putative transcriptional regulator, XRE family Plav_0339 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 154253510 Common - thiolase family protein Plav_3070 157 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154251951 Common - Beta-ketoacyl synthase Plav_1499 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252442 Common - ferredoxin-dependent glutamate synthase Plav_1995 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 154250546 Common - acetyl-CoA acetyltransferase Plav_0090 182 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253460 Common - iron-sulfur cluster assembly accessory protein Plav_3020 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 154251915 Common - ATP synthase F1, delta subunit Plav_1462 185 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 154251797 Common - transcriptional regulator, TetR family Plav_1344 44 COG1309 AcrR, Transcriptional regulator Transcription 154252947 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_2505 212 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154250653 Common - NAD-dependent epimerase/dehydratase Plav_0197 115 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154251325 Nonpathogen - hypothetical protein Plav_0869 1 None None None 154250740 Common - thioesterase superfamily protein Plav_0284 25 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154254058 Common - protein of unknown function DUF448 Plav_3627 37 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 154253396 Common - protein of unknown function DUF182 Plav_2956 115 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 154253600 Common - putative cold-shock DNA-binding domain protein Plav_3161 176 COG1278 CspC, Cold shock proteins Transcription 154252397 Common - 3-hydroxyacyl-CoA dehydrogenase NAD-binding Plav_1949 191 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 154253387 Common - fructose-1,6-bisphosphatase, class II Plav_2947 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 154250945 Common - Methyltransferase type 12 Plav_0489 28 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 154250818 Common - hypothetical protein Plav_0362 17 None None None 154254066 Common - Beta-ketoacyl synthase Plav_3635 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154250586 Common - short-chain dehydrogenase/reductase SDR Plav_0130 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252122 Common - diacylglycerol kinase catalytic region Plav_1670 100 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 154251672 Common - hypothetical protein Plav_1219 4 None None None 154251728 Common - methyltransferase GidB Plav_1275 186 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 154252186 Nonpathogen - Flp/Fap pilin component Plav_1734 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 154251882 Nonpathogen - hypothetical protein Plav_1429 1 None None None 154252367 Common - glycosyl transferase group 1 Plav_1919 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154251149 Common - dienelactone hydrolase Plav_0693 8 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 154253667 Common - histone family protein DNA-binding protein Plav_3229 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 154250976 Common - hypothetical protein Plav_0520 21 None None None 154251338 Common - peptide chain release factor 3 Plav_0882 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 154251379 Common - short-chain dehydrogenase/reductase SDR Plav_0923 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154253885 Common - short-chain dehydrogenase/reductase SDR Plav_3452 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154250631 Common - acriflavin resistance protein Plav_0175 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154251140 Common - Ribonuclease H Plav_0684 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 154250799 Nonpathogen - hypothetical protein Plav_0343 2 None None None 154250974 Nonpathogen - hypothetical protein Plav_0518 1 None None None 154251168 Common - large conductance mechanosensitive channel protein Plav_0712 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154252699 Common - dienelactone hydrolase Plav_2252 95 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 154250646 Common - PTS IIA-like nitrogen-regulatory protein PtsN Plav_0190 140 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 154251828 Common - beta-lactamase Plav_1375 122 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 154252352 Nonpathogen - hypothetical protein Plav_1904 1 None None None 154253766 Common - protein of unknown function UPF0118 Plav_3329 196 COG0628 PerM, Predicted permease General function prediction only 154252768 Common - protein of unknown function DUF541 Plav_2321 101 COG2968 COG2968, Uncharacterized conserved protein Function unknown 154251107 Common - transcriptional regulator, TetR family Plav_0651 119 COG1309 AcrR, Transcriptional regulator Transcription 154252932 Common - hypothetical protein Plav_2490 14 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 154250510 Nonpathogen - hypothetical protein Plav_0054 1 None None None 154253660 Common - NADH-quinone oxidoreductase, F subunit Plav_3221 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 154250591 Common - aminoglycoside phosphotransferase Plav_0135 86 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 154253788 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Plav_3351 164 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 154251047 Nonpathogen - hypothetical protein Plav_0591 6 None None None 154253085 Common - glucose-methanol-choline oxidoreductase Plav_2644 97 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 154252678 Common - hypothetical protein Plav_2231 37 COG5426 COG5426, Uncharacterized membrane protein Function unknown 154252643 Common - Glutathione S-transferase domain Plav_2196 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252852 Common - N-acetylmuramoyl-L-alanine amidase family 2 Plav_2410 110 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 154251034 Common - alpha/beta hydrolase fold Plav_0578 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253871 Common - Relaxase Plav_3435 29 None None None 154252752 Common - thioredoxin reductase Plav_2305 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 154253893 Common - beta-lactamase domain protein Plav_3460 132 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 154251782 Common - Extensin family protein Plav_1329 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 154252463 Common - Alpha/beta hydrolase fold-3 domain protein Plav_2016 123 COG0657 Aes, Esterase/lipase Lipid metabolism 154250939 Common - short-chain dehydrogenase/reductase SDR Plav_0483 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252009 Common - alanine dehydrogenase Plav_1557 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 154252063 Common - alpha/beta hydrolase fold Plav_1611 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253838 Nonpathogen - hypothetical protein Plav_3402 4 None None None 154250607 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Plav_0151 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 154253607 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Plav_3168 126 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 154252944 Nonpathogen - hypothetical protein Plav_2502 1 None None None 154253702 Common - transcriptional regulator, BadM/Rrf2 family Plav_3264 170 COG1959 COG1959, Predicted transcriptional regulator Transcription 154253747 Common - SAM (and some other nucleotide) binding motif Plav_3310 20 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 154252723 Common - excinuclease ABC, C subunit Plav_2276 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 154251162 Common - Excinuclease ABC C subunit domain protein Plav_0706 61 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 154251240 Nonpathogen - hypothetical protein Plav_0784 1 None None None 154253057 Common - short-chain dehydrogenase/reductase SDR Plav_2616 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252097 Common - AMP-dependent synthetase and ligase Plav_1645 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154254003 Common - protein of unknown function DUF486 Plav_3572 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 154251669 Common - hypothetical protein Plav_1216 20 None None None 154252078 Nonpathogen - hypothetical protein Plav_1626 1 None None None 154250461 Common - DNA replication and repair protein RecF Plav_0005 152 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 154253344 Common - glycerophosphoryl diester phosphodiesterase Plav_2904 168 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 154252332 Common - cytochrome c oxidase assembly protein CtaG/Cox11 Plav_1884 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 154252028 Common - polysaccharide deacetylase Plav_1576 112 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 154253851 Common - hypothetical protein Plav_3415 20 None None None 154253995 Common - Isoprenylcysteine carboxyl methyltransferase Plav_3564 33 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 154251429 Nonpathogen - hypothetical protein Plav_0973 10 None None None 154251731 Common - DNA polymerase III, delta subunit Plav_1278 34 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 154252449 Common - hypothetical protein Plav_2002 29 None None None 154251011 Common - alpha/beta hydrolase fold Plav_0555 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251774 Common - Heparinase II/III family protein Plav_1321 46 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 154250892 Common - protein of unknown function DUF952 Plav_0436 33 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 154250956 Common - sodium/hydrogen exchanger Plav_0500 158 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 154251730 Common - parB-like partition protein Plav_1277 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154250519 Nonpathogen - hypothetical protein Plav_0063 1 None None None 154254092 Common - Enoyl-CoA hydratase/isomerase Plav_3661 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253380 Common - protein of unknown function DUF6 transmembrane Plav_2940 50 None None None 154250667 Common - transcriptional regulator, MarR family Plav_0211 38 COG1846 MarR, Transcriptional regulators Transcription 154252859 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Plav_2417 207 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 154254047 Common - phospholipid/glycerol acyltransferase Plav_3616 80 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 154253665 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 3 Plav_3226 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 154250718 Common - methionyl-tRNA formyltransferase Plav_0262 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 154252902 Nonpathogen - hypothetical protein Plav_2460 1 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 154254031 Common - Methyltransferase type 11 Plav_3600 25 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154251791 Common - death-on-curing family protein Plav_1338 45 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 154252274 Nonpathogen - transcriptional regulator, XRE family Plav_1824 10 COG1476 COG1476, Predicted transcriptional regulators Transcription 154251376 Common - hypothetical protein Plav_0920 24 None None None 154251943 Common - hypothetical protein Plav_1490 25 COG4648 COG4648, Predicted membrane protein Function unknown 154252541 Common - protein of unknown function DUF1465 Plav_2094 21 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 154250472 Common - hypothetical protein Plav_0016 108 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 154250786 Common - integrase family protein Plav_0330 141 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154252163 Common - putative transcriptional regulator Plav_1711 53 COG2345 COG2345, Predicted transcriptional regulator Transcription 154250816 Common - Steryl-sulfatase Plav_0360 86 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154251615 Nonpathogen - hypothetical protein Plav_1161 2 None None None 154251333 Common - Fe-S metabolism associated SufE Plav_0877 95 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 154250487 Common - Sporulation domain protein Plav_0031 20 COG5373 COG5373, Predicted membrane protein Function unknown 154253950 Common - hypothetical protein Plav_3518 37 None None None 154252613 Nonpathogen - membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG) Plav_2166 10 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 154250879 Common - response regulator receiver protein Plav_0423 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154252648 Nonpathogen - hypothetical protein Plav_2201 1 None None None 154253725 Common - conserved hypothetical membrane-anchored protein Plav_3287 60 COG2323 COG2323, Predicted membrane protein Function unknown 154253731 Common - AsmA family protein Plav_3293 57 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 154251053 Common - PAS/PAC sensor signal transduction histidine kinase Plav_0597 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252731 Common - hypothetical protein Plav_2284 3 None None None 154253217 Common - siroheme synthase Plav_2776 62 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 154253727 Common - thiamine biosynthesis protein ThiS Plav_3289 64 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 154250886 Common - helicase c2 Plav_0430 114 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 154251045 Common - hypothetical protein Plav_0589 11 None None None 154252641 Common - Excinuclease ABC C subunit domain protein Plav_2194 67 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 154251424 Common - transcriptional regulator, MarR family Plav_0968 65 COG1846 MarR, Transcriptional regulators Transcription 154253814 Common - Cobyrinic acid ac-diamide synthase Plav_3377 21 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154252300 Common - multi-sensor hybrid histidine kinase Plav_1850 225 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 154251667 Common - PilT protein domain protein Plav_1214 52 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 154252173 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Plav_1721 68 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 154253124 Common - MaoC domain protein dehydratase Plav_2683 82 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154251365 Common - phage head-tail adaptor, putative Plav_0909 21 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 154253532 Common - membrane protein involved in aromatic hydrocarbon degradation Plav_3092 82 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 154250940 Common - hypothetical protein Plav_0484 23 COG3461 COG3461, Uncharacterized conserved protein Function unknown 154253305 Common - protein of unknown function DUF88 Plav_2865 61 COG1432 COG1432, Uncharacterized conserved protein Function unknown 154250463 Common - DNA gyrase, B subunit Plav_0007 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 154251438 Common - Acetamidase/Formamidase Plav_0982 66 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 154252264 Common - domain of unknown function DUF1738 Plav_1814 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 154250781 Nonpathogen - hypothetical protein Plav_0325 1 None None None 154251858 Common - heme exporter protein CcmB Plav_1405 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 154252519 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Plav_2072 231 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 154253499 Common - GreA/GreB family elongation factor Plav_3059 26 COG0782 GreA, Transcription elongation factor Transcription 154252099 Common - transcriptional regulator, TetR family Plav_1647 81 COG1309 AcrR, Transcriptional regulator Transcription 154251554 Common - ABC transporter related Plav_1100 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154251836 Common - hypothetical protein Plav_1383 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 154253232 Common - pantoate--beta-alanine ligase Plav_2791 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 154251172 Common - transcriptional regulator, TetR family Plav_0716 92 COG1309 AcrR, Transcriptional regulator Transcription 154252259 Common - Biopolymer transport protein-like protein Plav_1809 14 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154251872 Common - ribosomal protein S16 Plav_1419 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 154252454 Common - protein of unknown function DUF1329 Plav_2007 17 None None None 154253715 Common - N-acetylmuramoyl-L-alanine amidase Plav_3277 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 154250499 Common - methylated-DNA--protein-cysteine methyltransferase Plav_0043 207 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 154253536 Common - hemimethylated DNA binding protein Plav_3096 38 COG3785 COG3785, Uncharacterized conserved protein Function unknown 154251598 Common - Agmatine deiminase Plav_1144 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 154251084 Common - TspO and MBR like protein Plav_0628 60 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 154253035 Common - Phosphoglycerate mutase Plav_2594 82 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 154252059 Common - Electron transfer flavoprotein alpha subunit Plav_1607 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 154252434 Common - helix-turn-helix- domain containing protein AraC type Plav_1987 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154253891 Common - ribose-phosphate pyrophosphokinase Plav_3458 242 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 154253621 Common - lipid-A-disaccharide synthase Plav_3182 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 154253398 Common - VWA containing CoxE family protein Plav_2958 51 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 154253658 Common - NADH dehydrogenase (quinone) Plav_3219 189 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 154253341 Common - transcriptional regulator, MarR family Plav_2901 22 COG1846 MarR, Transcriptional regulators Transcription 154252759 Common - transcription elongation factor GreA Plav_2312 204 COG0782 GreA, Transcription elongation factor Transcription 154254010 Common - heat-inducible transcription repressor HrcA Plav_3579 149 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 154252146 Common - transcriptional regulator, CarD family Plav_1694 82 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 154252771 Common - hypothetical protein Plav_2324 7 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 154250742 Common - Prephenate dehydratase Plav_0286 164 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154251965 Nonpathogen - hypothetical protein Plav_1513 1 None None None 154251642 Common - P-type conjugative transfer protein TrbL Plav_1188 31 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 154251288 Common - beta-lactamase Plav_0832 75 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 154252387 Common - lytic murein transglycosylase Plav_1939 107 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 154252018 Common - short-chain dehydrogenase/reductase SDR Plav_1566 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251391 Common - L-carnitine dehydratase/bile acid-inducible protein F Plav_0935 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 154250612 Common - hypothetical protein Plav_0156 30 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154253046 Common - hypothetical protein Plav_2605 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 154250902 Common - hypothetical protein Plav_0446 27 None None None 154252190 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Plav_1738 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 154252811 Common - RES domain protein Plav_2368 26 None None None 154251851 Common - cytochrome c-type biogenesis protein CcmB Plav_1398 41 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 154252585 Common - D-3-phosphoglycerate dehydrogenase Plav_2138 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 154254017 Common - protein of unknown function UPF0102 Plav_3586 30 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 154251802 Common - porphobilinogen deaminase Plav_1349 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 154252483 Common - alpha/beta hydrolase fold Plav_2036 35 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253552 Common - ATPase involved in DNA replication Plav_3112 181 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 154251300 Common - Oligopeptidase B Plav_0844 102 COG1770 PtrB, Protease II Amino acid transport and metabolism 154253927 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Plav_3495 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 154253484 Common - Alkaline phosphatase Plav_3044 56 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 154253841 Common - helicase domain protein Plav_3405 17 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 154251518 Common - Enoyl-CoA hydratase/isomerase Plav_1063 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253474 Common - protein of unknown function DUF815 Plav_3034 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 154250573 Common - adenosylhomocysteinase Plav_0117 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 154250468 Common - polyhydroxyalkanoate depolymerase, intracellular Plav_0012 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 154253803 Common - UspA domain protein Plav_3366 35 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154250862 Common - BLUF domain protein Plav_0406 38 None None None 154251768 Common - SEC-C motif domain protein Plav_1315 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 154250856 Common - GcrA cell cycle regulator Plav_0400 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 154250870 Common - Radical SAM domain protein Plav_0414 24 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 154251540 Common - response regulator receiver protein Plav_1086 205 COG4566 TtrR, Response regulator Signal transduction mechanisms 154253644 Common - prolyl-tRNA synthetase Plav_3205 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154251864 Common - General substrate transporter Plav_1411 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251677 Common - hypothetical protein Plav_1224 24 None None None 154253605 Common - Triose-phosphate isomerase Plav_3166 237 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 154252971 Nonpathogen - hypothetical protein Plav_2529 1 None None None 154252378 Common - metal-dependent hydrolase-like protein Plav_1930 23 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 154253688 Common - DNA topoisomerase IV, B subunit Plav_3250 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 154250536 Common - two component transcriptional regulator, winged helix family Plav_0080 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154250714 Common - recombination protein RecR Plav_0258 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 154250900 Common - transcriptional regulator, TetR family Plav_0444 82 COG1309 AcrR, Transcriptional regulator Transcription 154253962 Common - replication protein A Plav_3531 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 154251862 Common - transcriptional regulator, MarR family Plav_1409 85 COG1846 MarR, Transcriptional regulators Transcription 154251319 Nonpathogen - hypothetical protein Plav_0863 1 None None None 154251685 Common - CHAD domain containing protein Plav_1232 83 COG3025 COG3025, Uncharacterized conserved protein Function unknown 154253848 Common - Lytic transglycosylase catalytic Plav_3412 44 None None None 154252790 Common - hypothetical protein Plav_2345 11 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 154252239 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Plav_1788 168 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 154252620 Common - hypothetical protein Plav_2173 32 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 154251848 Common - protein of unknown function UPF0005 Plav_1395 128 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 154252423 Common - ABC transporter related Plav_1976 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 154253369 Common - Appr-1-p processing domain protein Plav_2929 27 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 154251224 Common - GCN5-related N-acetyltransferase Plav_0768 60 COG0456 RimI, Acetyltransferases General function prediction only 154252883 Common - transcriptional regulator, TetR family Plav_2441 151 COG1309 AcrR, Transcriptional regulator Transcription 154250918 Common - acyl-CoA dehydrogenase domain protein Plav_0462 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253189 Common - ribosomal protein L5 Plav_2748 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 154252214 Common - aromatic-ring-hydroxylating dioxygenase beta subunit Plav_1762 23 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154252552 Common - Fructose-bisphosphate aldolase Plav_2105 36 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 154251891 Nonpathogen - hypothetical protein Plav_1438 1 None None None 154250947 Common - thioesterase superfamily protein Plav_0491 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251898 Nonpathogen - hypothetical protein Plav_1445 1 None None None 154252616 Common - hypothetical protein Plav_2169 21 None None None 154253243 Common - protein of unknown function DUF482 Plav_2802 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 154251242 Common - short-chain dehydrogenase/reductase SDR Plav_0786 227 COG0623 FabI, Enoyl- acyl-carrier-protein 154253998 Nonpathogen - hypothetical protein Plav_3567 3 None None None 154252344 Nonpathogen - Abortive infection protein Plav_1896 1 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 154251748 Nonpathogen - hypothetical protein Plav_1295 2 None None None 154252664 Common - NUDIX hydrolase Plav_2217 55 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 154253459 Nonpathogen - protein of unknown function DUF1457 Plav_3019 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252920 Common - transcriptional regulator, LysR family Plav_2478 125 COG0583 LysR, Transcriptional regulator Transcription 154252840 Common - toluene tolerance family protein Plav_2398 63 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 154252849 Common - 5-oxoprolinase (ATP-hydrolyzing) Plav_2407 114 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253250 Common - DNA-directed DNA polymerase Plav_2809 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 154251035 Nonpathogen - hypothetical protein Plav_0579 1 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154252847 Common - Carboxymuconolactone decarboxylase Plav_2405 22 COG2128 COG2128, Uncharacterized conserved protein Function unknown 154250578 Common - superoxide dismutase copper/zinc binding Plav_0122 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 154250701 Common - ABC transporter related Plav_0245 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 154252185 Common - mutator MutT protein Plav_1733 101 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 154251574 Common - putative undecaprenol kinase Plav_1120 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 154252157 Common - LAO/AO transport system ATPase Plav_1705 101 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 154252990 Common - HPP family protein? Plav_2548 111 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 154251508 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II Plav_1053 230 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 154253887 Common - sodium/glutamate symporter Plav_3454 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 154254070 Common - anaerobic glycerol-3-phosphate dehydrogenase subunit C Plav_3639 132 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 154251416 Common - acriflavin resistance protein Plav_0960 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154250909 Common - DEAD/H associated domain protein Plav_0453 195 COG1201 Lhr, Lhr-like helicases General function prediction only 154252833 Common - Activator of Hsp90 ATPase 1 family protein Plav_2390 20 COG3832 COG3832, Uncharacterized conserved protein Function unknown 154253405 Nonpathogen - hypothetical protein Plav_2965 1 None None None 154252002 Common - binding-protein-dependent transport systems inner membrane component Plav_1550 205 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 154252633 Common - flagellar hook capping protein Plav_2186 106 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 154252954 Common - protein of unknown function DUF140 Plav_2512 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 154253704 Common - protein of unknown function UPF0075 Plav_3266 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 154252405 Common - protein of unknown function DUF459 Plav_1957 28 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 154250985 Common - protein of unknown function DUF329 Plav_0529 31 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 154253024 Common - RNA-binding S4 domain protein Plav_2583 238 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 154250821 Common - Enoyl-CoA hydratase/isomerase Plav_0365 140 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253259 Nonpathogen - hypothetical protein Plav_2818 4 None None None 154251649 Common - hypothetical protein Plav_1195 23 None None None 154251741 Common - sulfotransferase Plav_1288 114 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 154251026 Common - AMP-dependent synthetase and ligase Plav_0570 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251983 Common - cytochrome c oxidase, cbb3-type, subunit II Plav_1531 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 154253273 Common - DNA protecting protein DprA Plav_2833 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 154251399 Common - protease Do Plav_0943 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 154254038 Common - outer membrane autotransporter barrel domain Plav_3607 71 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 154251238 Common - hemolysin A Plav_0782 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 154251928 Common - protein of unknown function DUF163 Plav_1475 163 COG1576 COG1576, Uncharacterized conserved protein Function unknown 154253271 Common - DNA topoisomerase I Plav_2831 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 154252911 Common - hypothetical protein Plav_2469 15 COG1647 COG1647, Esterase/lipase General function prediction only 154252746 Common - hypothetical protein Plav_2299 31 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 154253539 Common - major facilitator superfamily MFS_1 Plav_3099 106 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 154253566 Common - TrkA-N domain protein Plav_3126 157 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 154251020 Common - Cytochrome c oxidase subunit I type Plav_0564 170 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 154253756 Common - glycosyl transferase family 2 Plav_3319 160 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154252416 Common - multi-sensor hybrid histidine kinase Plav_1968 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252950 Common - Activator of Hsp90 ATPase 1 family protein Plav_2508 8 None None None 154250922 Common - protein of unknown function DUF1302 Plav_0466 18 None None None 154253674 Common - carbohydrate kinase, YjeF related protein Plav_3236 213 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 154252929 Common - Phosphoglycerate mutase Plav_2487 61 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 154251713 Common - transcription termination factor Rho Plav_1260 209 COG1158 Rho, Transcription termination factor Transcription 154252054 Common - argininosuccinate lyase Plav_1602 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 154253239 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Plav_2798 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 154251842 Common - protein of unknown function DUF1025 Plav_1389 50 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 154252901 Common - HflC protein Plav_2459 201 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 154251475 Common - short-chain dehydrogenase/reductase SDR Plav_1020 233 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154252894 Common - S-formylglutathione hydrolase Plav_2452 92 COG0627 COG0627, Predicted esterase General function prediction only 154250523 Nonpathogen - PE-PGRS family protein Plav_0067 1 None None None 154252821 Common - Endoribonuclease L-PSP Plav_2378 62 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 154253100 Common - hypothetical protein Plav_2659 14 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 154251407 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Plav_0951 174 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 154251066 Common - chaperonin GroEL Plav_0610 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 154253696 Common - FeS assembly SUF system protein Plav_3258 135 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 154253915 Common - protein of unknown function DUF140 Plav_3483 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 154250769 Nonpathogen - hypothetical protein Plav_0313 2 None None None 154250699 Common - transcriptional regulator, MarR family Plav_0243 17 COG1846 MarR, Transcriptional regulators Transcription 154252573 Common - ATP-dependent metalloprotease FtsH Plav_2126 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 154253986 Common - hypothetical protein Plav_3555 8 None None None 154253360 Common - Ubiquinol-cytochrome C chaperone Plav_2920 23 COG5452 COG5452, Uncharacterized conserved protein Function unknown 154253125 Common - acyl-CoA dehydrogenase domain protein Plav_2684 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253869 Common - hypothetical protein Plav_3433 21 None None None 154253610 Common - glutamine amidotransferase of anthranilate synthase Plav_3171 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 154250693 Common - type II secretion system protein Plav_0237 80 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 154251073 Common - GCN5-related N-acetyltransferase Plav_0617 37 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 154253843 Common - UvrD/REP helicase Plav_3407 227 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 154252234 Common - ferredoxin Plav_1783 75 COG0633 Fdx, Ferredoxin Energy production and conversion 154251122 Common - peptidase U62 modulator of DNA gyrase Plav_0666 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 154253544 Common - thioesterase superfamily protein Plav_3104 35 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251703 Common - protein-export protein SecB Plav_1250 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 154251457 Common - C-type lectin domain protein Plav_1001 145 None None None 154251019 Common - Cytochrome c oxidase subunit II Plav_0563 155 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 154251524 Common - Glutathione S-transferase domain Plav_1069 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253741 Common - acyltransferase 3 Plav_3303 84 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 154251992 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Plav_1540 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 154253588 Common - hypothetical protein Plav_3149 156 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 154254041 Common - UspA domain protein Plav_3610 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154253311 Common - pyridoxal phosphate biosynthetic protein PdxJ Plav_2871 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 154252710 Common - protein of unknown function DUF526 Plav_2263 34 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 154253943 Common - hypothetical protein Plav_3511 24 None None None 154251111 Nonpathogen - hypothetical protein Plav_0655 1 None None None 154250623 Nonpathogen - hypothetical protein Plav_0167 2 None None None 154250506 Common - PRC-barrel domain protein Plav_0050 18 COG1873 COG1873, Uncharacterized conserved protein Function unknown 154252918 Common - hypothetical protein Plav_2476 16 COG5470 COG5470, Uncharacterized conserved protein Function unknown 154252509 Nonpathogen - hypothetical protein Plav_2062 2 None None None 154252816 Common - transcriptional regulator, LysR family Plav_2373 133 COG0583 LysR, Transcriptional regulator Transcription 154250962 Common - histone family protein DNA-binding protein Plav_0506 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 154252345 Common - phosphoheptose isomerase Plav_1897 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 154252089 Common - glutamine synthetase catalytic region Plav_1637 220 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154251826 Common - aldo/keto reductase Plav_1373 35 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 154252474 Common - Saccharopine dehydrogenase Plav_2027 58 COG3268 COG3268, Uncharacterized conserved protein Function unknown 154251008 Common - AsmA family protein Plav_0552 67 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 154253671 Common - GCN5-related N-acetyltransferase Plav_3233 96 COG3153 COG3153, Predicted acetyltransferase General function prediction only 154253907 Common - replicative DNA helicase Plav_3475 215 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 154253210 Common - AsmA family protein Plav_2769 43 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 154251428 Common - hypothetical protein Plav_0972 4 None None None 154251711 Common - Ferrochelatase Plav_1258 175 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 154252972 Common - nucleotidyltransferase/DNA polymerase Plav_2530 71 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 154250878 Common - AMP-dependent synthetase and ligase Plav_0422 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253786 Common - glycosyl transferase family 2 Plav_3349 112 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154252725 Common - short-chain dehydrogenase/reductase SDR Plav_2278 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252802 Common - response regulator receiver protein Plav_2357 201 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154252853 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_2411 194 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154253449 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_3009 209 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 154253312 Common - holo-acyl-carrier-protein synthase Plav_2872 126 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 154250545 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_0089 201 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 154252217 Common - cytochrome P450 Plav_1765 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154250897 Common - thioesterase superfamily protein Plav_0441 53 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154253602 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Plav_3163 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 154253877 Common - RND efflux system, outer membrane lipoprotein, NodT family Plav_3444 122 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154253058 Nonpathogen - hypothetical protein Plav_2617 1 None None None 154251588 Common - two component transcriptional regulator, LuxR family Plav_1134 207 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154252672 Common - short-chain dehydrogenase/reductase SDR Plav_2225 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253308 Common - (p)ppGpp synthetase I, SpoT/RelA Plav_2868 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 154252172 Common - tyrosine recombinase XerD Plav_1720 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154250931 Nonpathogen - transcriptional regulator, TetR family Plav_0475 1 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 154252679 Common - hypothetical protein Plav_2232 31 None None None 154252755 Common - conserved hypothetical cytosolic protein Plav_2308 5 None None None 154251173 Common - Lytic transglycosylase catalytic Plav_0717 166 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154251519 Common - Antibiotic biosynthesis monooxygenase Plav_1064 13 COG1359 COG1359, Uncharacterized conserved protein Function unknown 154250541 Nonpathogen - putative membrane protein, glycine-rich Plav_0085 1 COG5281 COG5281, Phage-related minor tail protein Function unknown 154250596 Common - FolC bifunctional protein Plav_0140 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 154252926 Common - hypothetical protein Plav_2484 11 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154251611 Common - hypothetical protein Plav_1157 30 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 154253361 Common - conserved hypothetical cytosolic protein Plav_2921 30 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 154253138 Common - hypothetical protein Plav_2697 16 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 154251109 Common - 4-hydroxybenzoate polyprenyl transferase Plav_0653 195 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 154252733 Nonpathogen - hypothetical protein Plav_2286 1 None None None 154253705 Common - tyrosyl-tRNA synthetase Plav_3267 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154252591 Common - Adenylosuccinate synthase Plav_2144 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 154253349 Common - ATP-cone domain protein Plav_2909 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 154253333 Nonpathogen - hypothetical protein Plav_2893 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154251266 Common - Enoyl-CoA hydratase/isomerase Plav_0810 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154250569 Common - HPr kinase Plav_0113 22 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 154253698 Common - FeS assembly protein SufD Plav_3260 181 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 154251814 Common - protein of unknown function DUF1302 Plav_1361 18 None None None 154252334 Common - Aldose 1-epimerase Plav_1886 43 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 154253939 Common - short-chain dehydrogenase/reductase SDR Plav_3507 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154253224 Common - acetyl-CoA acetyltransferase Plav_2783 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154250880 Common - glycosyl transferase family 2 Plav_0424 123 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154250517 Common - MOSC domain containing protein Plav_0061 44 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 154252229 Common - GntR domain protein Plav_1778 122 COG2186 FadR, Transcriptional regulators Transcription 154253982 Common - hypothetical protein Plav_3551 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 154252834 Common - regulatory protein ArsR Plav_2391 56 COG0640 ArsR, Predicted transcriptional regulators Transcription 154253342 Common - protein of unknown function DUF1295 Plav_2902 34 COG3752 COG3752, Predicted membrane protein Function unknown 154252720 Common - molybdopterin biosynthesis MoaE protein Plav_2273 157 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 154252435 Common - YceI family protein Plav_1988 120 COG2353 COG2353, Uncharacterized conserved protein Function unknown 154251619 Common - Cyclohexanone monooxygenase Plav_1165 52 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154253282 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Plav_2842 175 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 154251000 Common - malto-oligosyltrehalose trehalohydrolase Plav_0544 170 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 154253385 Common - aminotransferase class I and II Plav_2945 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 154253424 Common - extracellular solute-binding protein family 3 Plav_2984 107 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154252000 Common - spermidine/putrescine ABC transporter ATPase subunit Plav_1548 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 154252618 Common - hypothetical protein Plav_2171 30 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 154253912 Common - UspA domain protein Plav_3480 127 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154254059 Common - translation initiation factor IF-2 Plav_3628 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 154253794 Common - Beta-ketoacyl synthase Plav_3357 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154250661 Common - glycosyl transferase group 1 Plav_0205 178 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154250850 Common - phosphate ABC transporter, periplasmic binding protein Plav_0394 120 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 154250592 Common - Nucleotidyl transferase Plav_0136 216 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 154252022 Nonpathogen - hypothetical protein Plav_1570 1 None None None 154250817 Nonpathogen - putative transcriptional regulator, TetR family Plav_0361 8 None None None 154250565 Common - Phosphoenolpyruvate carboxykinase (ATP) Plav_0109 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 154250588 Common - transcriptional regulator, TetR family Plav_0132 78 COG1309 AcrR, Transcriptional regulator Transcription 154253421 Common - FAD-linked oxidoreductase Plav_2981 34 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 154251785 Common - hypothetical protein Plav_1332 22 None None None 154251142 Common - hydroxymethylbutenyl pyrophosphate reductase Plav_0686 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 154254039 Common - tryptophanyl-tRNA synthetase Plav_3608 235 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154251995 Nonpathogen - hypothetical protein Plav_1543 2 None None None 154251377 Nonpathogen - hypothetical protein Plav_0921 1 None None None 154252256 Common - acyl-CoA dehydrogenase domain protein Plav_1805 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251441 Common - NADPH-dependent FMN reductase Plav_0985 24 COG0431 COG0431, Predicted flavoprotein General function prediction only 154251497 Common - hypothetical protein Plav_1042 2 None None None 154252697 Common - OsmC family protein Plav_2250 98 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 154251360 Nonpathogen - hypothetical protein Plav_0904 2 None None None 154253296 Common - Methyltransferase type 12 Plav_2856 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252871 Common - UDP-3-0-acyl N-acetylglucosamine deacetylase Plav_2429 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 154251355 Common - putative transmembrane protein Plav_0899 28 COG4852 COG4852, Predicted membrane protein Function unknown 154252369 Common - UDP-glucose 6-dehydrogenase Plav_1921 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 154250836 Common - beta-lactamase domain protein Plav_0380 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 154251468 Nonpathogen - K+-transporting ATPase, F subunit Plav_1012 1 None None None 154250655 Common - Glutathione S-transferase domain Plav_0199 102 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154250978 Common - hypothetical protein Plav_0522 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 154251757 Common - nitrogen regulatory protein P-II Plav_1304 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 154253752 Nonpathogen - hypothetical protein Plav_3315 4 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 154253804 Common - heavy metal translocating P-type ATPase Plav_3367 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154252382 Common - galactokinase Plav_1934 121 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 154251190 Common - quinolinate synthetase complex, A subunit Plav_0734 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 154253592 Common - histidine kinase Plav_3153 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253895 Common - transcriptional regulator, LysR family Plav_3462 191 COG0583 LysR, Transcriptional regulator Transcription 154252204 Common - short-chain dehydrogenase/reductase SDR Plav_1752 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252326 Common - Glutathione S-transferase domain Plav_1878 80 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252548 Common - Inositol-phosphate phosphatase Plav_2101 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 154253165 Common - NusG antitermination factor Plav_2724 215 COG0250 NusG, Transcription antiterminator Transcription 154253641 Nonpathogen - hypothetical protein Plav_3202 1 None None None 154253831 Common - hypothetical protein Plav_3395 10 None None None 154251443 Common - short-chain dehydrogenase/reductase SDR Plav_0987 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154252621 Common - two component transcriptional regulator, winged helix family Plav_2174 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154252553 Common - Phosphoglycerate kinase Plav_2106 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 154252628 Common - flagellar motor switch protein FliN Plav_2181 125 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 154250767 Common - peptidase S58 DmpA Plav_0311 52 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251458 Common - ABC transporter related Plav_1002 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 154252465 Common - acyl-CoA dehydrogenase domain protein Plav_2018 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251203 Common - DNA-3-methyladenine glycosylase I Plav_0747 133 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 154253122 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Plav_2681 225 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 154250756 Nonpathogen - ribonuclease P protein component Plav_0300 16 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 154252535 Common - thioesterase superfamily protein Plav_2088 58 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154252026 Common - acetoacetyl-CoA reductase Plav_1574 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252566 Common - Tol-Pal system TolQ Plav_2119 152 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154251799 Nonpathogen - hypothetical protein Plav_1346 1 None None None 154253926 Common - hypothetical protein Plav_3494 19 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 154251942 Common - phosphopantetheine-binding Plav_1489 7 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154254007 Common - 2OG-Fe(II) oxygenase Plav_3576 56 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 154252148 Common - protein of unknown function DUF1332 Plav_1696 37 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 154252408 Nonpathogen - hypothetical protein Plav_1960 1 None None None 154253944 Common - domain of unknown function DUF1738 Plav_3512 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 154252866 Common - D-alanine--D-alanine ligase Plav_2424 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 154250840 Common - surface antigen (D15) Plav_0384 138 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 154251230 Common - Sua5/YciO/YrdC/YwlC family protein Plav_0774 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 154252878 Common - UvrD/REP helicase Plav_2436 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 154253319 Nonpathogen - hypothetical protein Plav_2879 1 None None None 154250992 Common - citrate/H+ symporter, CitMHS family Plav_0536 35 COG2851 CitM, H+/citrate symporter Energy production and conversion 154251725 Common - tRNA modification GTPase TrmE Plav_1272 217 COG0486 ThdF, Predicted GTPase General function prediction only 154251625 Common - GMP synthase, large subunit Plav_1171 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 154251255 Common - AMP-dependent synthetase and ligase Plav_0799 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253324 Common - TrkA-C domain protein Plav_2884 105 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 154253746 Common - glycosyl transferase family 2 Plav_3309 177 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154252797 Common - Integrase catalytic region Plav_2352 59 None None None 154250728 Common - OmpA/MotB domain protein Plav_0272 172 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154252687 Common - Coproporphyrinogen oxidase Plav_2240 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 154252095 Common - GCN5-related N-acetyltransferase Plav_1643 98 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 154250526 Common - type II and III secretion system protein Plav_0070 133 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 154251773 Common - thioesterase superfamily protein Plav_1320 61 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251199 Nonpathogen - hypothetical protein Plav_0743 9 None None None 154252680 Common - protein of unknown function DUF58 Plav_2233 51 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 154253993 Common - phage transcriptional regulator, AlpA Plav_3562 21 COG3311 AlpA, Predicted transcriptional regulator Transcription 154253519 Common - DEAD/DEAH box helicase domain protein Plav_3079 211 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 154252772 Common - outer membrane autotransporter barrel domain Plav_2325 63 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 154251696 Common - hypothetical protein Plav_1243 4 None None None 154253440 Common - polysaccharide export protein Plav_3000 96 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 154253919 Common - amidophosphoribosyltransferase Plav_3487 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 154253972 Common - P-type conjugative transfer ATPase TrbB Plav_3541 144 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 154250889 Nonpathogen - hypothetical protein Plav_0433 4 None None None 154251013 Common - Glutathione S-transferase domain Plav_0557 67 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154250610 Common - AMP-dependent synthetase and ligase Plav_0154 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251208 Common - Quinone oxidoreductase putative YhdH/YhfP Plav_0752 102 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154253076 Common - protein of unknown function DUF192 Plav_2635 89 COG1430 COG1430, Uncharacterized conserved protein Function unknown 154252606 Common - RNA polymerase, sigma 32 subunit, RpoH Plav_2159 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 154250669 Nonpathogen - hypothetical protein Plav_0213 1 None None None 154251967 Common - protein of unknown function DUF107 Plav_1515 68 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 154253969 Common - hypothetical protein Plav_3538 28 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 154252979 Nonpathogen - hypothetical protein Plav_2537 1 None None None 154253181 Common - ribosomal protein S19 Plav_2740 241 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 154251949 Common - tryptophan halogenase Plav_1497 50 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 154252362 Common - glycosyl transferase group 1 Plav_1914 120 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154252155 Nonpathogen - hypothetical protein Plav_1703 1 None None None 154252495 Nonpathogen - hypothetical protein Plav_2048 1 None None None 154252124 Nonpathogen - regulatory protein LuxR Plav_1672 4 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 154253375 Common - Enoyl-CoA hydratase/isomerase Plav_2935 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253545 Common - protein of unknown function DUF72 Plav_3105 103 COG1801 COG1801, Uncharacterized conserved protein Function unknown 154251349 Common - NMT1/THI5 like domain protein Plav_0893 80 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 154253018 Common - multi-sensor hybrid histidine kinase Plav_2576 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253238 Common - ATP-dependent Clp protease adaptor protein ClpS Plav_2797 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 154250760 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Plav_0304 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154253629 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Plav_3190 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 154253025 Common - glutaredoxin-like protein Plav_2584 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 154251331 Common - Chromosomal replication initiator DnaA domain Plav_0875 11 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 154253177 Common - ribosomal protein L3 Plav_2736 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 154253147 Nonpathogen - hypothetical protein Plav_2706 3 None None None 154250673 Common - Post-segregation antitoxin CcdA Plav_0217 6 COG5302 COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid General function prediction only 154252317 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Plav_1868 163 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 154251564 Common - RarD protein, DMT superfamily transporter Plav_1110 97 COG2962 RarD, Predicted permeases General function prediction only 154252298 Nonpathogen - hypothetical protein Plav_1848 2 None None None 154250849 Common - multi-sensor signal transduction histidine kinase Plav_0393 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 154253011 Common - hypothetical protein Plav_2569 11 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 154253219 Common - magnesium transporter Plav_2778 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 154252305 Nonpathogen - hypothetical protein Plav_1855 1 None None None 154252076 Common - acyl-CoA dehydrogenase domain protein Plav_1624 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251100 Common - RNA-binding S4 domain protein Plav_0644 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 154253140 Common - diguanylate phosphodiesterase Plav_2699 127 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 154253284 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Plav_2844 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 154250842 Common - helix-turn-helix domain protein Plav_0386 26 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 154254084 Common - cysteine synthase A Plav_3653 223 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 154253110 Common - 3-demethylubiquinone-9 3-methyltransferase Plav_2669 66 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 154251217 Nonpathogen - putative transmembrane protein Plav_0761 2 None None None 154250480 Common - hypothetical protein Plav_0024 221 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 154253159 Common - aminotransferase class-III Plav_2718 233 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 154252418 Common - heat shock protein Hsp20 Plav_1971 80 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 154252654 Nonpathogen - hypothetical protein Plav_2207 1 None None None 154251790 Common - Creatininase Plav_1337 84 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 154253279 Common - insertion element protein Plav_2839 8 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 154253624 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Plav_3185 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 154253609 Common - monooxygenase FAD-binding Plav_3170 82 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 154251984 Common - cytochrome c oxidase, cbb3-type, subunit I Plav_1532 136 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 154251228 Common - beta-lactamase Plav_0772 135 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 154252493 Common - hypothetical protein Plav_2046 14 COG4190 COG4190, Predicted transcriptional regulator Transcription 154252101 Common - Hyaluronidase Plav_1649 13 None None None 154253774 Common - Leucyl aminopeptidase Plav_3337 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 154251323 Common - hypothetical protein Plav_0867 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 154253248 Common - Glyoxylate reductase Plav_2807 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 154250808 Nonpathogen - hypothetical protein Plav_0352 5 None None None 154252763 Common - DNA primase Plav_2316 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 154251660 Common - hypothetical protein Plav_1206 10 COG5419 COG5419, Uncharacterized conserved protein Function unknown 154253828 Common - hypothetical protein Plav_3392 9 None None None 154253040 Common - DNA repair protein RadC Plav_2599 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 154251408 Nonpathogen - hypothetical protein Plav_0952 1 None None None 154251328 Nonpathogen - protein of unknown function DUF1457 Plav_0872 3 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252041 Nonpathogen - hypothetical protein Plav_1589 1 None None None 154252825 Common - isochorismatase hydrolase Plav_2382 75 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 154251481 Common - hypothetical protein Plav_1026 88 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154251023 Common - protein of unknown function DUF819 Plav_0567 12 COG5505 COG5505, Predicted integral membrane protein Function unknown 154253612 Common - Indole-3-glycerol-phosphate synthase Plav_3173 217 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 154251096 Common - hypothetical protein Plav_0640 29 COG3897 COG3897, Predicted methyltransferase General function prediction only 154250904 Common - alpha/beta hydrolase fold Plav_0448 143 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252743 Common - Glutathione S-transferase domain Plav_2296 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252925 Common - rod shape-determining protein RodA Plav_2483 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 154251937 Common - Phosphatidylcholine synthase Plav_1484 23 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 154253548 Common - rare lipoprotein A Plav_3108 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 154253699 Common - FeS assembly ATPase SufC Plav_3261 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 154252315 Common - TonB-dependent receptor Plav_1865 82 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154252992 Common - flagellar FlbT family protein Plav_2550 18 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 154250774 Common - UBA/THIF-type NAD/FAD binding protein Plav_0318 64 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 154251164 Common - glycosyl transferase family 2 Plav_0708 122 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154250928 Common - Alpha/beta hydrolase fold-3 domain protein Plav_0472 131 COG0657 Aes, Esterase/lipase Lipid metabolism 154251068 Common - transcriptional regulator, TetR family Plav_0612 142 COG1309 AcrR, Transcriptional regulator Transcription 154251414 Common - GCN5-related N-acetyltransferase Plav_0958 10 COG0456 RimI, Acetyltransferases General function prediction only 154252065 Common - acyl-CoA dehydrogenase domain protein Plav_1613 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251112 Common - protein of unknown function DUF558 Plav_0656 177 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 154250575 Nonpathogen - hypothetical protein Plav_0119 1 None None None 154253744 Common - dTDP-glucose 4,6-dehydratase Plav_3306 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 154253481 Common - gid protein Plav_3041 118 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 154252512 Common - PepSY-associated TM helix domain protein Plav_2065 36 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 154252823 Common - response regulator receiver protein Plav_2380 214 COG4566 TtrR, Response regulator Signal transduction mechanisms 154251931 Common - gamma-glutamyl phosphate reductase Plav_1478 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 154251912 Common - putative transaldolase Plav_1459 153 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 154252347 Nonpathogen - hypothetical protein Plav_1899 2 None None None 154251920 Common - hypothetical protein Plav_1467 10 COG1633 COG1633, Uncharacterized conserved protein Function unknown 154251126 Common - Cytochrome c oxidase subunit I type Plav_0670 172 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 154252053 Nonpathogen - hypothetical protein Plav_1601 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 154251902 Nonpathogen - hypothetical protein Plav_1449 1 None None None 154253563 Common - GTP-binding protein HSR1-related Plav_3123 215 COG2262 HflX, GTPases General function prediction only 154250629 Common - hypothetical protein Plav_0173 89 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 154252504 Nonpathogen - aa3 type cytochrome c oxidase subunit IV Plav_2057 1 None None None 154251913 Common - primosomal protein N' Plav_1460 210 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 154251124 Nonpathogen - hypothetical protein Plav_0668 1 None None None 154252713 Common - regulatory protein TetR Plav_2266 18 None None None 154251397 Common - cytochrome c-type biogenesis protein CcmF Plav_0941 132 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 154250860 Common - Hsp33 protein Plav_0404 133 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 154251226 Common - FAD linked oxidase domain protein Plav_0770 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 154252118 Common - HAD-superfamily subfamily IIA hydrolase like protein Plav_1666 70 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 154251406 Common - putative signal transduction protein with EFhand domain Plav_0950 30 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 154250600 Common - Phosphoribosylanthranilate isomerase Plav_0144 193 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 154254008 Common - NnrUfamily protein Plav_3577 45 COG4094 COG4094, Predicted membrane protein Function unknown 154252444 Common - N-formylglutamate amidohydrolase Plav_1997 56 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 154250823 Common - aminoglycoside phosphotransferase Plav_0367 14 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 154251821 Common - short-chain dehydrogenase/reductase SDR Plav_1368 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251632 Common - hypothetical protein Plav_1178 7 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 154251662 Common - transcriptional regulator, XRE family Plav_1209 13 None None None 154252646 Common - putative cold-shock DNA-binding domain protein Plav_2199 176 COG1278 CspC, Cold shock proteins Transcription 154250946 Common - 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase Plav_0490 27 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154252949 Common - regulatory protein ArsR Plav_2507 78 COG0640 ArsR, Predicted transcriptional regulators Transcription 154250520 Common - response regulator receiver protein Plav_0064 185 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154250731 Common - short-chain dehydrogenase/reductase SDR Plav_0275 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154253403 Common - carbon monoxide dehydrogenase subunit G Plav_2963 43 COG3427 COG3427, Uncharacterized conserved protein Function unknown 154253883 Common - hypothetical protein Plav_3450 21 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154253979 Common - Conjugal transfer protein Plav_3548 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 154252276 Common - AAA ATPase central domain protein Plav_1826 234 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 154251637 Common - transcriptional regulator, LysR family Plav_1183 189 COG0583 LysR, Transcriptional regulator Transcription 154253652 Common - proton-translocating NADH-quinone oxidoreductase, chain N Plav_3213 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 154251701 Common - import inner membrane translocase subunit Tim44 Plav_1248 40 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 154251570 Nonpathogen - hypothetical protein Plav_1116 1 None None None 154253258 Nonpathogen - hypothetical protein Plav_2817 2 None None None 154250638 Common - periplasmic binding protein Plav_0182 151 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 154252586 Nonpathogen - hypothetical protein Plav_2139 2 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252039 Common - protein of unknown function DUF1006 Plav_1587 61 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 154253270 Common - ribonuclease R Plav_2830 192 COG0557 VacB, Exoribonuclease R Transcription 154253757 Common - TDP-4-keto-6-deoxy-D-glucose transaminase Plav_3320 195 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 154252528 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Plav_2081 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 154250726 Common - glutathione peroxidase Plav_0270 113 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 154254055 Common - tRNA (guanine-N(7)-)-methyltransferase Plav_3624 174 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 154251239 Common - 23S rRNA (uracil-5-)-methyltransferase RumA Plav_0783 148 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 154253062 Common - sulfatase Plav_2621 70 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154252328 Nonpathogen - hypothetical protein Plav_1880 1 None None None 154251166 Common - putative transcriptional regulator, CopG/Arc/MetJ family Plav_0710 31 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 154251606 Common - Hydantoinase B/oxoprolinase Plav_1152 93 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251665 Nonpathogen - hypothetical protein Plav_1212 10 None None None 154252799 Common - beta-lactamase domain protein Plav_2354 81 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154251502 Common - plasmid stabilization system Plav_1047 6 COG3668 ParE, Plasmid stabilization system protein General function prediction only 154252952 Common - putative Chase2 sensor protein Plav_2510 71 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 154251188 Common - nicotinate-nucleotide pyrophosphorylase Plav_0732 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 154251489 Common - AMP-dependent synthetase and ligase Plav_1034 216 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253418 Common - Ku domain containing protein Plav_2978 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 154251683 Common - phosphoribosyl-ATP pyrophosphohydrolase Plav_1230 150 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 154250801 Nonpathogen - hypothetical protein Plav_0345 1 None None None 154250986 Common - efflux transporter, RND family, MFP subunit Plav_0530 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154252371 Common - GDP-mannose 4,6-dehydratase Plav_1923 227 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 154252845 Common - methionine synthase Plav_2403 168 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 154252183 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Plav_1731 153 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 154251771 Common - hypothetical protein Plav_1318 22 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 154254001 Common - phosphoglycerate mutase 1 family Plav_3570 182 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 154251845 Common - lipolytic protein G-D-S-L family Plav_1392 110 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 154250988 Common - RND efflux system, outer membrane lipoprotein, NodT family Plav_0532 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154252092 Common - transcriptional regulator, TetR family Plav_1640 34 COG1309 AcrR, Transcriptional regulator Transcription 154252193 Common - cytochrome c Plav_1741 41 COG3245 CycB, Cytochrome c5 Energy production and conversion 154250921 Common - 3-hydroxyacyl-CoA dehydrogenase NAD-binding Plav_0465 188 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 154252539 Common - Quinone oxidoreductase putative PIG3 Plav_2092 204 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154250594 Common - Double-strand break repair helicase AddA Plav_0138 216 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 154253200 Common - ribosomal protein S11 Plav_2759 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 154251043 Nonpathogen - hypothetical protein Plav_0587 2 None None None 154252453 Common - putative exporter of RND superfamily Plav_2006 71 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 154251833 Common - radical SAM enzyme, Cfr family Plav_1380 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 154253846 Common - hypothetical protein Plav_3410 13 None None None 154252669 Common - flavoprotein WrbA Plav_2222 99 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 154251534 Common - transcriptional regulator, TetR family Plav_1079 122 COG1309 AcrR, Transcriptional regulator Transcription 154253207 Common - CrcB protein Plav_2766 60 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 154252596 Common - thiamine biosynthesis protein ThiC Plav_2149 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 154251645 Common - AAA ATPase Plav_1191 69 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 154252886 Common - arylsulfate sulfotransferase-like protein Plav_2444 31 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 154253102 Common - putative signal-transduction protein with CBS domains Plav_2661 178 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 154253581 Common - Pyruvate dehydrogenase (acetyl-transferring) Plav_3141 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 154254079 Common - short-chain dehydrogenase/reductase SDR Plav_3648 225 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154253733 Common - cellulase-like protein Plav_3295 31 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 154251893 Common - hypothetical protein Plav_1440 3 None None None 154253347 Common - transcriptional regulator, MucR family Plav_2907 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 154250496 Common - dethiobiotin synthase Plav_0040 144 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 154252236 Common - 4-hydroxyphenylacetate 3-hydroxylase Plav_1785 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 154253317 Common - DNA topoisomerase IV, A subunit Plav_2877 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 154250869 Nonpathogen - hypothetical protein Plav_0413 1 None None None 154251867 Common - MiaB-like tRNA modifying enzyme Plav_1414 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 154253516 Common - aminoglycoside phosphotransferase Plav_3076 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 154253940 Nonpathogen - hypothetical protein Plav_3508 1 None None None 154251298 Nonpathogen - protein of unknown function DUF1254 Plav_0842 9 COG5436 COG5436, Predicted integral membrane protein Function unknown 154252961 Common - sulfatase Plav_2519 84 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154251831 Common - DSBA oxidoreductase Plav_1378 55 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 154252581 Common - phenazine biosynthesis protein PhzF family Plav_2134 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 154251389 Nonpathogen - hypothetical protein Plav_0933 6 None None None 154250478 Nonpathogen - aminoglycoside phosphotransferase Plav_0022 3 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 154251640 Common - P-type conjugative transfer protein TrbG Plav_1186 53 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 154254019 Common - hypothetical protein Plav_3588 49 COG2912 COG2912, Uncharacterized conserved protein Function unknown 154252977 Common - ABC transporter related Plav_2535 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154253486 Nonpathogen - hypothetical protein Plav_3046 2 None None None 154252224 Common - Enoyl-CoA hydratase/isomerase Plav_1772 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252437 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Plav_1990 24 None None None 154250534 Nonpathogen - TadE family protein Plav_0078 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 154251522 Common - short-chain dehydrogenase/reductase SDR Plav_1067 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252481 Common - hypothetical protein Plav_2034 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 154253466 Common - putative transcriptional regulator Plav_3026 141 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 154250494 Nonpathogen - hypothetical protein Plav_0038 4 None None None 154252161 Common - MATE efflux family protein Plav_1709 164 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 154252980 Nonpathogen - hypothetical protein Plav_2538 1 None None None 154254060 Common - ribosome-binding factor A Plav_3629 91 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 154251069 Nonpathogen - hypothetical protein Plav_0613 1 None None None 154253867 Common - hypothetical protein Plav_3431 23 None None None 154250696 Common - TRAP transporter solute receptor, TAXI family Plav_0240 80 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 154252219 Common - short-chain dehydrogenase/reductase SDR Plav_1767 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252399 Common - cytochrome P450 Plav_1951 72 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154253364 Common - integration host factor, alpha subunit Plav_2924 184 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 154251647 Common - Conjugal transfer protein TrbC Plav_1193 23 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 154252390 Common - transglutaminase domain protein Plav_1942 91 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 154253952 Common - putative plasmid stability protein StbC Plav_3520 26 COG4691 StbC, Plasmid stability protein General function prediction only 154251357 Common - NUDIX hydrolase Plav_0901 28 None None None 154251875 Common - ribosomal protein L19 Plav_1422 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 154252545 Common - OmpA/MotB domain protein Plav_2098 154 COG1360 MotB, Flagellar motor protein Cell motility and secretion 154251192 Common - hypothetical protein Plav_0736 57 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 154253164 Common - preprotein translocase, SecE subunit Plav_2723 22 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 154251838 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Plav_1385 45 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 154250759 Common - SNARE associated Golgi protein Plav_0303 15 COG0398 COG0398, Uncharacterized conserved protein Function unknown 154253479 Common - hypothetical protein Plav_3039 35 COG3748 COG3748, Predicted membrane protein Function unknown 154253710 Common - peptidase M23B Plav_3272 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154250954 Common - transcriptional regulator, TetR family Plav_0498 60 COG1309 AcrR, Transcriptional regulator Transcription 154253493 Common - Queuosine biosynthesis protein Plav_3053 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 154251657 Common - Cobyrinic acid ac-diamide synthase Plav_1203 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154251651 Common - hypothetical protein Plav_1197 28 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 154252262 Common - transcriptional regulator, XRE family Plav_1812 73 COG1396 HipB, Predicted transcriptional regulators Transcription 154253457 Common - glutathione-dependent formaldehyde-activating GFA Plav_3017 67 COG3791 COG3791, Uncharacterized conserved protein Function unknown 154253712 Common - HI0933 family protein Plav_3274 140 COG2081 COG2081, Predicted flavoproteins General function prediction only 154252380 Common - Undecaprenyl-phosphate galactose phosphotransferase Plav_1932 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 154252970 Nonpathogen - hypothetical protein Plav_2528 1 None None None 154252521 Common - sulfate ABC transporter, inner membrane subunit CysW Plav_2074 221 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 154252662 Common - Methyltransferase type 11 Plav_2215 148 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154250489 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Plav_0033 235 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 154253310 Common - hypothetical protein Plav_2870 38 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 154253508 Common - Sporulation domain protein Plav_3068 74 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 154251136 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Plav_0680 188 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 154253546 Nonpathogen - hypothetical protein Plav_3106 1 None None None 154252169 Common - 3-dehydroquinate synthase Plav_1717 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 154250788 Common - FRG domain protein Plav_0332 19 None None None 154252626 Common - flagellar biosynthesis protein FlhA Plav_2179 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 154251175 Common - Electron-transferring-flavoprotein dehydrogenase Plav_0719 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 154251572 Common - hypothetical protein Plav_1118 14 None None None 154250689 Common - type II and III secretion system protein Plav_0233 139 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 154254021 Nonpathogen - hypothetical protein Plav_3590 1 None None None 154252985 Common - flagellar hook-associated protein FlgK Plav_2543 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 154251617 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Plav_1163 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 154252774 Common - integral membrane sensor hybrid histidine kinase Plav_2327 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253392 Common - Silent information regulator protein Sir2 Plav_2952 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 154253016 Common - flagellar biosynthetic protein FliR Plav_2574 129 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 154252938 Nonpathogen - hypothetical protein Plav_2496 1 None None None 154253435 Common - hypothetical protein Plav_2995 17 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 154253575 Common - cyclase/dehydrase Plav_3135 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 154252556 Common - hypothetical protein Plav_2109 13 None None None 154251086 Common - Inositol-phosphate phosphatase Plav_0630 196 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 154252635 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Plav_2188 218 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 154252701 Common - MaoC domain protein dehydratase Plav_2254 60 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154250682 Common - TadE family protein Plav_0226 16 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 154250815 Common - acetyl-CoA acetyltransferase Plav_0359 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253631 Common - undecaprenyl diphosphate synthase Plav_3192 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 154251158 Common - DNA methylase N-4/N-6 domain protein Plav_0702 141 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 154251281 Common - transcriptional regulator, LysR family Plav_0825 154 COG0583 LysR, Transcriptional regulator Transcription 154250550 Common - protein of unknown function DUF454 Plav_0094 14 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 154251596 Common - ornithine carbamoyltransferase Plav_1142 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 154253573 Common - phosphatidylglycerophosphatase A Plav_3133 72 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 154250783 Common - Phosphoglycerate mutase Plav_0327 116 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 154253681 Common - nitrogen regulatory protein P-II Plav_3243 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 154252244 Common - Alkanal monooxygenase (FMN-linked) Plav_1793 110 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154252340 Common - Urea carboxylase Plav_1892 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 154251419 Common - beta-lactamase Plav_0963 81 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 154253719 Common - DSBA oxidoreductase Plav_3281 110 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 154253967 Common - protein of unknown function DUF736 Plav_3536 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154252873 Common - DNA repair protein RecN Plav_2431 197 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 154253037 Common - transcriptional regulator, AbrB family Plav_2596 15 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 154253501 Common - Carbonate dehydratase Plav_3061 149 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 154253335 Common - Orn/DAP/Arg decarboxylase 2 Plav_2895 168 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 154252476 Common - alpha/beta hydrolase fold Plav_2029 124 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252240 Common - HpcH/HpaI aldolase Plav_1789 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 154253812 Common - hypothetical protein Plav_3375 14 None None None 154251380 Common - acyl-CoA dehydrogenase domain protein Plav_0924 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253717 Common - gamma-glutamyltranspeptidase Plav_3279 108 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 154253080 Nonpathogen - hypothetical protein Plav_2639 2 None None None 154253806 Common - heavy metal efflux pump, CzcA family Plav_3369 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 154252153 Nonpathogen - hypothetical protein Plav_1701 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154253170 Common - DNA-directed RNA polymerase, beta subunit Plav_2729 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 154250912 Common - hypothetical protein Plav_0456 28 None None None 154251466 Common - putative transcriptional regulator, Crp/Fnr family Plav_1010 160 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154251978 Common - heavy metal translocating P-type ATPase Plav_1526 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154251620 Common - Ppx/GppA phosphatase Plav_1166 177 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 154250750 Common - pyrimidine 5'-nucleotidase Plav_0294 46 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 154251118 Common - putative DNA topology modulation protein FlaR Plav_0662 49 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 154251472 Common - two component transcriptional regulator, winged helix family Plav_1017 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154252133 Nonpathogen - protein of unknown function DUF1457 Plav_1681 3 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154253854 Common - hypothetical protein Plav_3418 18 None None None 154253383 Common - poly(R)-hydroxyalkanoic acid synthase, class I Plav_2943 74 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154251853 Common - hypothetical protein Plav_1400 8 None None None 154252296 Common - hypothetical protein Plav_1846 27 None None None 154254069 Common - Rubrerythrin Plav_3638 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 154252258 Common - acyl-CoA dehydrogenase domain protein Plav_1807 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154250563 Common - hypothetical protein Plav_0107 12 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154250657 Common - Tetratricopeptide domain protein Plav_0201 36 None None None 154251627 Common - phage transcriptional regulator, AlpA Plav_1173 21 COG3311 AlpA, Predicted transcriptional regulator Transcription 154252855 Common - S-adenosyl-methyltransferase MraW Plav_2413 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 154251412 Common - PAS/PAC sensor signal transduction histidine kinase Plav_0956 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252727 Common - sodium/hydrogen exchanger Plav_2280 187 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 154253023 Common - RNA methyltransferase, TrmH family, group 1 Plav_2581 152 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 154250482 Nonpathogen - hypothetical protein Plav_0026 2 None None None 154252043 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Plav_1591 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 154251824 Common - protein of unknown function DUF167 Plav_1371 16 COG1872 COG1872, Uncharacterized conserved protein Function unknown 154251479 Common - aldehyde dehydrogenase Plav_1024 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154251755 Common - Rh family protein/ammonium transporter Plav_1302 200 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 154252201 Common - hypothetical protein Plav_1749 31 None None None 154253514 Common - hypothetical protein Plav_3074 12 None None None 154251375 Common - gene transfer agent (GTA) like protein Plav_0919 26 None None None 154252850 Common - heat shock protein DnaJ domain protein Plav_2408 74 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 154252758 Common - putative transcriptional regulator, AsnC family Plav_2311 154 COG1522 Lrp, Transcriptional regulators Transcription 154251982 Nonpathogen - Cbb3-type cytochrome oxidase component Plav_1530 3 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 154251219 Common - transcriptional regulator, MarR family Plav_0763 30 COG1846 MarR, Transcriptional regulators Transcription 154252020 Nonpathogen - hypothetical protein Plav_1568 2 None None None 154250834 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Plav_0378 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 154250933 Common - hypothetical protein Plav_0477 8 COG0824 FcbC, Predicted thioesterase General function prediction only 154252936 Common - glycosyl transferase group 1 Plav_2494 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154251028 Common - alpha/beta hydrolase fold Plav_0572 69 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253792 Common - domain of unknown function DUF1732 Plav_3355 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 154253002 Common - SAF domain protein Plav_2560 45 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 154253280 Common - Auxin Efflux Carrier Plav_2840 75 COG0679 COG0679, Predicted permeases General function prediction only 154250832 Common - TonB-dependent siderophore receptor Plav_0376 93 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 154254043 Common - nitroreductase Plav_3612 48 COG0778 NfnB, Nitroreductase Energy production and conversion 154251881 Common - Citryl-CoA lyase Plav_1428 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 154251676 Common - domain of unknown function DUF1738 Plav_1223 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 154251501 Common - putative transcriptional regulator, CopG/Arc/MetJ family Plav_1046 20 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 154251495 Common - hypothetical protein Plav_1040 3 None None None 154252695 Common - class II aldolase/adducin family protein Plav_2248 143 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 154253879 Common - ABC transporter related Plav_3446 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154250637 Common - transport system permease protein Plav_0181 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154251787 Common - L-carnitine dehydratase/bile acid-inducible protein F Plav_1334 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 154252109 Common - short-chain dehydrogenase/reductase SDR Plav_1657 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253447 Nonpathogen - hypothetical protein Plav_3007 1 None None None 154252067 Common - hypothetical protein Plav_1615 2 None None None 154251532 Common - protein of unknown function DUF1457 Plav_1077 4 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154253875 Common - hypothetical protein Plav_3441 10 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 154253604 Nonpathogen - protein of unknown function DUF1457 Plav_3165 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252215 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Plav_1763 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 154253761 Common - ribonuclease D Plav_3324 122 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 154253087 Nonpathogen - hypothetical protein Plav_2646 1 None None None 154253784 Common - methyltransferase Plav_3347 41 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154250806 Common - copper-translocating P-type ATPase Plav_0350 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154252289 Common - P-type conjugative transfer protein TrbJ Plav_1839 23 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 154252488 Common - response regulator receiver protein Plav_2041 212 COG4566 TtrR, Response regulator Signal transduction mechanisms 154251244 Common - Sel1 domain protein repeat-containing protein Plav_0788 96 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154253212 Common - carboxyl transferase Plav_2771 212 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 154251146 Common - Glycine dehydrogenase (decarboxylating) Plav_0690 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 154250859 Common - ornithine carbamoyltransferase Plav_0403 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 154250704 Common - extracellular solute-binding protein family 5 Plav_0248 159 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 154251585 Common - sulfatase Plav_1131 87 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154252372 Common - NAD-dependent epimerase/dehydratase Plav_1924 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 154250543 Common - protein of unknown function DUF1302 Plav_0087 18 None None None 154251144 Common - glycine cleavage system T protein Plav_0688 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 154251586 Common - protein of unknown function DUF323 Plav_1132 88 COG1262 COG1262, Uncharacterized conserved protein Function unknown 154252024 Common - polyhydroxyalkonate synthesis repressor, PhaR Plav_1572 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 154253521 Common - transcription-repair coupling factor Plav_3081 221 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 154254089 Common - ubiquinone/menaquinone biosynthesis methyltransferase Plav_3658 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154251547 Common - succinic semialdehyde dehydrogenase Plav_1093 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154253469 Common - Sec-independent protein translocase, TatC subunit Plav_3029 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 154253897 Common - transcriptional regulator, LysR family Plav_3464 20 COG0583 LysR, Transcriptional regulator Transcription 154251805 Common - HemY domain protein Plav_1352 27 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 154252479 Common - N-formylglutamate amidohydrolase Plav_2032 39 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 154250936 Common - hypothetical protein Plav_0480 12 COG2267 PldB, Lysophospholipase Lipid metabolism 154252719 Common - thioesterase superfamily protein Plav_2272 29 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251812 Common - protein of unknown function DUF87 Plav_1359 89 COG0433 COG0433, Predicted ATPase General function prediction only 154252336 Common - binding-protein-dependent transport systems inner membrane component Plav_1888 177 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 154254046 Common - ferric uptake regulator, Fur family Plav_3615 191 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154250567 Common - two component transcriptional regulator, winged helix family Plav_0111 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154253340 Common - 3-hydroxyisobutyrate dehydrogenase Plav_2900 173 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 154252685 Nonpathogen - hypothetical protein Plav_2238 1 None None None 154253900 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Plav_3468 79 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154251517 Common - integral membrane sensor signal transduction histidine kinase Plav_1062 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252674 Common - periplasmic solute binding protein Plav_2227 163 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 154252472 Nonpathogen - ribosomal protein L36 Plav_2025 1 None None None 154253331 Nonpathogen - Biopolymer transport protein ExbD/TolR Plav_2891 1 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154251723 Common - protein of unknown function DUF255 Plav_1270 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 154252093 Common - hypothetical protein Plav_1641 14 COG5031 COQ4, Uncharacterized protein involved in ubiquinone biosynthesis Coenzyme metabolism 154251971 Common - short-chain dehydrogenase/reductase SDR Plav_1519 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253823 Common - cation efflux protein Plav_3386 43 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 154254062 Common - ribosomal protein S15 Plav_3631 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 154250952 Common - acyl-CoA dehydrogenase domain protein Plav_0496 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252907 Common - acetolactate synthase, small subunit Plav_2465 189 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 154253464 Common - Beta-N-acetylhexosaminidase Plav_3024 166 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 154253937 Common - FAD dependent oxidoreductase Plav_3505 14 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 154251311 Common - Male sterility domain Plav_0855 47 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154251511 Common - PhnA protein Plav_1056 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 154253051 Common - metal dependent phosphohydrolase Plav_2610 16 COG4341 COG4341, Predicted HD phosphohydrolase General function prediction only 154250598 Common - tryptophan synthase, alpha subunit Plav_0142 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 154253670 Common - Endopeptidase Clp Plav_3232 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154251595 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Plav_1141 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 154253119 Common - TPR repeat-containing protein Plav_2678 85 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 154252307 Nonpathogen - hypothetical protein Plav_1857 1 None None None 154252341 Common - Allophanate hydrolase Plav_1893 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154253112 Common - regulatory protein ArsR Plav_2671 104 COG0640 ArsR, Predicted transcriptional regulators Transcription 154254051 Common - CBS domain containing protein Plav_3620 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 154253133 Common - Carbamoyl-phosphate synthase L chain ATP-binding Plav_2692 232 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 154253864 Common - protein of unknown function DUF1527 Plav_3428 22 None None None 154250663 Common - translation initiation factor IF-3 Plav_0207 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 154251432 Common - OmpW family protein Plav_0976 73 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 154252530 Common - AMP-dependent synthetase and ligase Plav_2083 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252411 Common - glutamate synthase, NADH/NADPH, small subunit Plav_1963 188 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 154252497 Common - two component, sigma54 specific, transcriptional regulator, Fis family Plav_2050 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154250847 Common - short-chain dehydrogenase/reductase SDR Plav_0391 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154253910 Common - protein of unknown function DUF1538 Plav_3478 23 None None None 154252940 Common - FAD dependent oxidoreductase Plav_2498 23 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 154251344 Common - hypothetical protein Plav_0888 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 154251948 Common - putative lipoprotein transmembrane Plav_1496 20 COG4258 COG4258, Predicted exporter General function prediction only 154253439 Common - Non-specific protein-tyrosine kinase Plav_2999 165 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 154254086 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Plav_3655 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 154253265 Common - major facilitator superfamily MFS_1 Plav_2825 105 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 154252364 Common - glycosyl transferase group 1 Plav_1916 179 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154253141 Common - NUDIX hydrolase Plav_2700 46 None None None 154251102 Common - acyl-CoA dehydrogenase domain protein Plav_0646 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253858 Common - putative secreted protein Plav_3422 21 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 154253353 Common - 6,7-dimethyl-8-ribityllumazine synthase Plav_2913 212 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 154251336 Common - protein of unknown function DUF1491 Plav_0880 32 COG5447 COG5447, Uncharacterized conserved protein Function unknown 154253754 Common - hypothetical protein Plav_3317 16 None None None 154251321 Nonpathogen - hypothetical protein Plav_0865 1 None None None 154252792 Common - putative DNA-binding protein Plav_2347 61 COG3943 COG3943, Virulence protein General function prediction only 154253150 Common - helix-turn-helix- domain containing protein AraC type Plav_2709 10 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154253776 Common - permease YjgP/YjgQ family protein Plav_3339 124 COG0795 COG0795, Predicted permeases General function prediction only 154251092 Common - transcriptional regulator Plav_0636 23 None None None 154251487 Common - acyl-CoA dehydrogenase domain protein Plav_1032 142 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253686 Common - Protein of unknown function YqcI/YcgG Plav_3248 10 COG3403 COG3403, Uncharacterized conserved protein Function unknown 154253066 Common - FAD dependent oxidoreductase Plav_2625 124 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 154252515 Common - peptide deformylase Plav_2068 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 154252809 Common - tryptophanyl-tRNA synthetase Plav_2364 235 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154252074 Common - hypothetical protein Plav_1622 12 None None None 154251904 Common - beta-lactamase domain protein Plav_1451 96 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 154252800 Common - PAS/PAC sensor signal transduction histidine kinase Plav_2355 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154253472 Common - protein-L-isoaspartate O-methyltransferase Plav_3032 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 154252199 Common - peptide chain release factor 1 Plav_1747 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 154251792 Nonpathogen - MazG nucleotide pyrophosphohydrolase Plav_1339 1 COG1694 MazG, Predicted pyrophosphatase General function prediction only 154253179 Common - Ribosomal protein L25/L23 Plav_2738 228 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 154253735 Common - NADH:ubiquinone oxidoreductase 17.2 kD subunit Plav_3297 39 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 154252430 Common - amidohydrolase 2 Plav_1983 47 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 154250883 Common - sterol desaturase-like protein Plav_0427 69 COG3000 ERG3, Sterol desaturase Lipid metabolism 154251528 Common - protein of unknown function DUF899 thioredoxin family protein Plav_1073 27 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 154252904 Common - phosphoserine phosphatase SerB Plav_2462 153 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 154251197 Nonpathogen - hypothetical protein Plav_0741 4 None None None 154252896 Common - SMP-30/Gluconolaconase/LRE domain protein Plav_2454 80 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 154250458 Common - Rhodanese domain protein Plav_0002 38 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 154250749 Common - DNA mismatch repair protein MutL Plav_0293 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 154250620 Common - major facilitator superfamily MFS_1 Plav_0164 5 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154252206 Common - peptidase M23B Plav_1754 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154251201 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Plav_0745 16 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 154251206 Common - dihydroorotase, multifunctional complex type Plav_0750 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 154252537 Common - protein of unknown function DUF1013 Plav_2090 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 154251210 Common - Lysine exporter protein (LYSE/YGGA) Plav_0754 8 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 154251567 Common - ABC transporter related Plav_1113 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 154253945 Common - ParB domain protein nuclease Plav_3513 158 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154250552 Common - YidE/YbjL duplication Plav_0096 53 COG2985 COG2985, Predicted permease General function prediction only 154250618 Common - protein of unknown function DUF1302 Plav_0162 18 None None None 154253097 Common - Carotenoid oxygenase Plav_2656 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 154253078 Nonpathogen - hypothetical protein Plav_2637 1 None None None 154251456 Common - outer membrane efflux protein Plav_1000 28 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154253844 Common - hypothetical protein Plav_3408 72 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 154252652 Common - acyl-CoA dehydrogenase domain protein Plav_2205 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253639 Common - bifunctional deaminase-reductase domain protein Plav_3200 49 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 154253442 Common - hypothetical protein Plav_3002 15 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 154250791 Common - ExsB family protein Plav_0335 81 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 154250999 Common - glycogen debranching enzyme GlgX Plav_0543 144 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 154251232 Common - sodium/glutamate symporter Plav_0776 16 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 154250754 Common - GTP-binding protein HSR1-related Plav_0298 182 COG0218 COG0218, Predicted GTPase General function prediction only 154252568 Common - hypothetical protein Plav_2121 29 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154252142 Common - two component transcriptional regulator, LuxR family Plav_1690 157 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154252514 Common - ribosomal protein S21 Plav_2067 40 None None None 154251514 Common - putative intracellular septation protein Plav_1059 50 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 154251099 Common - putative methyltransferase Plav_0643 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 154251960 Common - catalase/peroxidase HPI Plav_1508 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 154250624 Common - DSBA oxidoreductase Plav_0168 33 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 154252864 Common - UDP-N-acetylmuramate--alanine ligase Plav_2422 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 154253157 Common - hypothetical protein Plav_2716 33 COG3652 COG3652, Predicted outer membrane protein Function unknown 154253833 Common - hypothetical protein Plav_3397 11 None None None 154251921 Common - hypothetical protein Plav_1468 3 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 154254076 Common - protein of unknown function DUF1044 Plav_3645 27 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 154251544 Common - hypothetical protein Plav_1090 92 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 154253821 Common - single-strand binding protein/Primosomal replication protein n Plav_3384 18 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 154253654 Common - proton-translocating NADH-quinone oxidoreductase, chain L Plav_3215 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 154253977 Common - hypothetical protein Plav_3546 9 None None None 154251277 Common - acyl-CoA dehydrogenase domain protein Plav_0821 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251531 Nonpathogen - protein of unknown function DUF1457 Plav_1076 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154253183 Common - ribosomal protein S3 Plav_2742 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 154251819 Common - acyl-CoA dehydrogenase domain protein Plav_1366 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252814 Common - hypothetical protein Plav_2371 33 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 154252876 Common - peptidase M24 Plav_2434 226 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 154252561 Common - protein of unknown function DUF28 Plav_2114 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 154251302 Common - MaoC domain protein dehydratase Plav_0846 65 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154252011 Common - ribosomal protein L32 Plav_1559 95 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 154252888 Common - protein of unknown function DUF1321 Plav_2446 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 154252694 Common - eIF-2B alpha/beta/delta-related uncharacterized protein Plav_2247 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 154253455 Common - AraC-type transcriptional regulator domain protein Plav_3015 117 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154252668 Common - Pirin domain protein Plav_2221 139 COG1741 COG1741, Pirin-related protein General function prediction only 154250942 Nonpathogen - hypothetical protein Plav_0486 1 None None None 154251268 Common - TonB-dependent receptor plug Plav_0812 128 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 154252007 Common - membrane protein-like protein Plav_1555 25 COG3205 COG3205, Predicted membrane protein Function unknown 154252088 Common - NADPH-dependent FMN reductase Plav_1636 48 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 154253359 Common - SmpA/OmlA domain protein Plav_2919 34 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 154253980 Common - P-type conjugative transfer protein TrbG Plav_3549 53 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 154252570 Common - Peptidoglycan-associated lipoprotein Plav_2123 152 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154253740 Common - aspartyl-tRNA synthetase Plav_3302 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154253917 Common - DNA repair protein RadA Plav_3485 216 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 154253970 Common - TRAG family protein Plav_3539 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 154252036 Common - Prephenate dehydrogenase Plav_1584 165 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 154251270 Common - peptidase M42 family protein Plav_0814 77 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 154250556 Nonpathogen - hypothetical protein Plav_0100 7 None None None 154252608 Common - helix-turn-helix domain protein Plav_2161 21 COG1395 COG1395, Predicted transcriptional regulator Transcription 154251754 Common - aminotransferase class I and II Plav_1301 218 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 154253167 Common - ribosomal protein L1 Plav_2726 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 154253377 Common - ribosomal protein L13 Plav_2937 223 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 154250997 Common - trehalose synthase Plav_0541 171 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 154251655 Common - hypothetical protein Plav_1201 23 None None None 154252913 Common - regulatory protein ArsR Plav_2471 21 COG0640 ArsR, Predicted transcriptional regulators Transcription 154253401 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Plav_2961 114 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 154252402 Common - RelE-like cytotoxic translational repressor of toxin-antitoxin stability system Plav_1954 28 None None None 154254033 Common - metal dependent phosphohydrolase Plav_3602 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 154251504 Common - integrase family protein Plav_1049 78 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154251078 Common - peptidase M23B Plav_0622 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154253881 Common - hypothetical protein Plav_3448 5 None None None 154251639 Common - conjugation TrbI family protein Plav_1185 57 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 154252072 Common - Rhodanese domain protein Plav_1620 57 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 154251029 Common - luciferase family protein Plav_0573 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154251353 Common - penicillin-binding protein, 1A family Plav_0897 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 154250708 Common - Prephenate dehydratase Plav_0252 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 154250752 Common - protein of unknown function DUF1036 Plav_0296 19 COG5480 COG5480, Predicted integral membrane protein Function unknown 154252786 Common - hypothetical protein Plav_2341 64 COG4717 COG4717, Uncharacterized conserved protein Function unknown 154252322 Common - acyl-CoA dehydrogenase domain protein Plav_1873 129 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251778 Common - Methyltransferase type 12 Plav_1325 150 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154250825 Common - monooxygenase FAD-binding Plav_0369 71 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 154253256 Common - response regulator receiver modulated diguanylate cyclase Plav_2815 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 154252141 Common - putative phage repressor Plav_1689 45 COG2932 COG2932, Predicted transcriptional regulator Transcription 154253370 Common - Glutathione S-transferase domain Plav_2930 95 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251395 Common - Peptidoglycan-binding domain 1 protein Plav_0939 10 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 154252116 Nonpathogen - hypothetical protein Plav_1664 2 None None None 154251186 Common - cell wall hydrolase SleB Plav_0730 46 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 154251923 Common - NUDIX hydrolase Plav_1470 116 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 154254074 Common - Glyoxylate reductase Plav_3643 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 154254024 Common - hypothetical protein Plav_3593 6 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 154253664 Common - NADH-quinone oxidoreductase, B subunit Plav_3225 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 154251745 Common - thioesterase superfamily protein Plav_1292 52 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251032 Common - Amidohydrolase 3 Plav_0576 77 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 154252812 Common - hypothetical protein Plav_2369 28 None None None 154251557 Common - NAD+ synthetase Plav_1103 231 COG0171 NadE, NAD synthase Coenzyme metabolism 154253529 Common - Phosphoglycerate mutase Plav_3089 41 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 154250724 Common - diguanylate phosphodiesterase Plav_0268 88 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 154253506 Common - Nucleotidyl transferase Plav_3066 232 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 154251561 Common - homocysteine S-methyltransferase Plav_1107 38 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 154252034 Common - chorismate mutase Plav_1582 13 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 154252577 Common - dihydropteroate synthase Plav_2130 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 154253191 Common - ribosomal protein S8 Plav_2750 245 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 154252329 Nonpathogen - hypothetical protein Plav_1881 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 154250780 Common - hypothetical protein Plav_0324 16 None None None 154252659 Common - response regulator receiver protein Plav_2212 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154250514 Common - MgtC/SapB transporter Plav_0058 113 COG1285 SapB, Uncharacterized membrane protein Function unknown 154251257 Common - beta-lactamase domain protein Plav_0801 121 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154252843 Common - 5,10-methylenetetrahydrofolate reductase Plav_2401 160 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 154252401 Common - helix-turn-helix domain protein Plav_1953 49 COG2944 COG2944, Predicted transcriptional regulator Transcription 154254053 Common - transcriptional regulator, XRE family Plav_3622 37 COG1396 HipB, Predicted transcriptional regulators Transcription 154252226 Common - Alkanal monooxygenase (FMN-linked) Plav_1774 122 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154253901 Common - hypothetical protein Plav_3469 5 None None None 154253371 Common - Activator of Hsp90 ATPase 1 family protein Plav_2931 48 COG3832 COG3832, Uncharacterized conserved protein Function unknown 154253277 Common - acyl-CoA dehydrogenase domain protein Plav_2837 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252310 Common - hypothetical protein Plav_1860 6 None None None 154252776 Nonpathogen - hypothetical protein Plav_2329 1 None None None 154250981 Common - protein of unknown function DUF541 Plav_0525 28 COG2859 COG2859, Uncharacterized protein conserved in bacteria Function unknown 154253064 Common - alpha/beta hydrolase fold Plav_2623 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252358 Common - polysaccharide biosynthesis protein Plav_1910 88 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 154250580 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Plav_0124 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 154250776 Common - Resolvase domain Plav_0320 68 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 154252741 Common - sortase family protein Plav_2294 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 154251098 Common - HAD-superfamily subfamily IIA hydrolase like protein Plav_0642 78 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 154252827 Common - protein of unknown function DUF894 DitE Plav_2384 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154252994 Common - hypothetical protein Plav_2552 42 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 154253298 Common - hypothetical protein Plav_2858 15 None None None 154251717 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1264 175 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154250688 Common - SAF domain protein Plav_0232 52 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 154251997 Common - acetyl-CoA acetyltransferase Plav_1545 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154251131 Common - Surfeit locus 1 family protein Plav_0675 37 COG3346 COG3346, Uncharacterized conserved protein Function unknown 154253419 Nonpathogen - transport-associated protein Plav_2979 5 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 154251114 Common - glutamate--cysteine ligase Plav_0658 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 154253014 Nonpathogen - flagellar hook-basal body complex subunit FliE Plav_2572 2 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 154252090 Common - Creatininase Plav_1638 83 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 154253483 Common - Amidase Plav_3043 216 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154250464 Common - penicillin-binding protein, 1A family Plav_0008 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 154250476 Common - plasmid maintenance system killer Plav_0020 62 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 154250926 Common - ThiJ/PfpI domain protein Plav_0470 122 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 154251869 Common - LmbE family protein Plav_1416 36 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 154250876 Nonpathogen - hypothetical protein Plav_0420 5 None None None 154252055 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Plav_1603 144 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 154252050 Common - response regulator receiver protein Plav_1598 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154252506 Common - NAD(P) transhydrogenase subunit alpha part Plav_2059 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 154253862 Common - DNA repair protein RadC Plav_3426 173 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 154252637 Common - hypothetical protein Plav_2190 6 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 154251973 Common - protein of unknown function DUF188 Plav_1521 90 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 154252467 Common - major facilitator superfamily MFS_1 Plav_2020 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154250690 Common - pilus (Caulobacter type) biogenesis lipoprotein CpaD Plav_0234 16 COG5461 COG5461, Type IV pili component Cell motility and secretion 154253408 Common - NADH-ubiquinone oxidoreductase chain 4L Plav_2968 46 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 154251404 Common - FAD dependent oxidoreductase Plav_0948 55 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 154251128 Nonpathogen - hypothetical protein Plav_0672 4 None None None 154251578 Common - Amidohydrolase 3 Plav_1124 111 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 154251234 Common - histone deacetylase superfamily Plav_0778 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 154251454 Common - Biopolymer transport protein ExbD/TolR Plav_0998 37 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154253888 Common - Poly-beta-hydroxybutyrate polymerase domain protein Plav_3455 76 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154250492 Common - biotin synthase Plav_0036 182 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 154251910 Common - integrase family protein Plav_1457 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154250502 Common - Alcohol dehydrogenase zinc-binding type 2 Plav_0046 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 154253561 Common - MazG family protein Plav_3121 157 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 154253152 Common - major facilitator superfamily MFS_1 Plav_2711 104 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251154 Common - hypothetical protein Plav_0698 13 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 154251761 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Plav_1308 120 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 154252923 Common - rod shape-determining protein MreD Plav_2481 9 None None None 154251018 Common - hypothetical protein Plav_0562 10 COG1981 COG1981, Predicted membrane protein Function unknown 154252958 Common - hypothetical protein Plav_2516 88 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154252111 Common - Carboxymuconolactone decarboxylase Plav_1659 34 COG2128 COG2128, Uncharacterized conserved protein Function unknown 154252171 Nonpathogen - hypothetical protein Plav_1719 8 None None None 154253692 Common - diguanylate cyclase Plav_3254 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 154252898 Common - protein of unknown function DUF1428 Plav_2456 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 154252740 Common - transcriptional regulator, TetR family Plav_2293 132 COG1309 AcrR, Transcriptional regulator Transcription 154253947 Common - hypothetical protein Plav_3515 9 None None None 154250627 Common - efflux transporter, RND family, MFP subunit Plav_0171 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154251710 Common - uroporphyrinogen decarboxylase Plav_1257 180 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 154253104 Common - Phosphoribosyl-AMP cyclohydrolase Plav_2663 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 154251795 Common - YCII-related Plav_1342 37 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 154253326 Common - OmpA/MotB domain protein Plav_2886 112 COG1360 MotB, Flagellar motor protein Cell motility and secretion 154253135 Common - Glutathione S-transferase domain Plav_2694 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253263 Common - hypothetical protein Plav_2823 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251021 Nonpathogen - hypothetical protein Plav_0565 2 None None None 154253759 Common - Methyltransferase type 12 Plav_3322 53 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252735 Common - excinuclease ABC, B subunit Plav_2288 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 154252178 Common - Citrate transporter Plav_1726 147 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 154252374 Common - UTP-glucose-1-phosphate uridylyltransferase Plav_1926 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 154252486 Common - putative transcriptional regulator, Crp/Fnr family Plav_2039 148 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154250852 Common - phosphate ABC transporter, inner membrane subunit PstA Plav_0396 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 154251847 Common - protein of unknown function DUF214 Plav_1394 87 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 154253526 Nonpathogen - hypothetical protein Plav_3086 1 None None None 154250944 Nonpathogen - hypothetical protein Plav_0488 1 None None None 154253810 Common - putative transcriptional regulator, MerR family Plav_3373 139 COG0789 SoxR, Predicted transcriptional regulators Transcription 154252765 Common - Methyltransferase type 11 Plav_2318 150 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252269 Common - plasmid transfer protein TraF Plav_1819 29 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154253495 Common - Pyrrolo-quinoline quinone Plav_3055 59 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 154254013 Common - putative oxygen-independent coproporphyrinogen III oxidase Plav_3582 212 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 154253789 Common - CDP-glucose 4,6-dehydratase Plav_3352 159 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154251386 Common - 17 kDa surface antigen Plav_0930 25 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 154252644 Common - hypothetical protein Plav_2197 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 154253289 Common - Sel1 domain protein repeat-containing protein Plav_2849 25 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154251088 Common - hypothetical protein Plav_0632 30 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 154252987 Common - hypothetical protein Plav_2545 10 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 154251138 Common - hypothetical protein Plav_0682 65 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 154251246 Common - pyridoxamine 5'-phosphate oxidase Plav_0790 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 154251156 Common - DSBA oxidoreductase Plav_0700 93 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 154252428 Common - alpha/beta hydrolase fold Plav_1981 67 COG2267 PldB, Lysophospholipase Lipid metabolism 154251905 Common - succinyl-CoA synthetase, beta subunit Plav_1452 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 154253412 Common - multiple resistance and pH regulation protein F Plav_2972 22 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 154252081 Common - Auxin Efflux Carrier Plav_1629 86 COG0679 COG0679, Predicted permeases General function prediction only 154253633 Common - uridylate kinase Plav_3194 245 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 154251261 Nonpathogen - hypothetical protein Plav_0805 1 None None None 154254023 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Plav_3592 37 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 154252291 Common - Conjugal transfer protein Plav_1841 30 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 154252458 Nonpathogen - hypothetical protein Plav_2011 1 None None None 154250865 Common - O-succinylhomoserine sulfhydrylase Plav_0409 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 154253236 Common - ATPase MipZ Plav_2795 25 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154251417 Common - efflux transporter, RND family, MFP subunit Plav_0961 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154252246 Common - amidohydrolase 2 Plav_1795 34 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 154250711 Common - DNA polymerase III, subunits gamma and tau Plav_0255 244 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 154252013 Nonpathogen - hypothetical protein Plav_1561 12 None None None 154251291 Common - ABC transporter related Plav_0835 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 154253129 Common - hypothetical protein Plav_2688 17 None None None 154253721 Common - Inositol phosphatase/fructose-16-bisphosphatase Plav_3283 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 154253801 Common - hypothetical protein Plav_3364 6 None None None 154251663 Nonpathogen - hypothetical protein Plav_1210 1 None None None 154252260 Common - hypothetical protein Plav_1810 18 COG5419 COG5419, Uncharacterized conserved protein Function unknown 154253577 Common - sulfatase Plav_3137 75 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 154250471 Common - Ankyrin Plav_0015 100 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 154253437 Common - hypothetical protein Plav_2997 20 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 154253555 Common - beta-lactamase-like protein Plav_3115 69 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 154253394 Common - alpha amylase catalytic region Plav_2954 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 154253683 Common - hypothetical protein Plav_3245 33 COG3911 COG3911, Predicted ATPase General function prediction only 154252278 Nonpathogen - hypothetical protein Plav_1828 6 None None None 154252167 Common - BolA family protein Plav_1715 110 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 154252393 Nonpathogen - hypothetical protein Plav_1945 1 None None None 154251876 Common - 3-isopropylmalate dehydratase, large subunit Plav_1423 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 154251037 Nonpathogen - hypothetical protein Plav_0581 1 None None None 154252242 Common - hypothetical protein Plav_1791 14 None None None 154250867 Nonpathogen - LrgA family protein Plav_0411 2 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 154251593 Common - SNARE associated Golgi protein Plav_1139 76 COG0398 COG0398, Uncharacterized conserved protein Function unknown 154253209 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Plav_2768 158 COG0546 Gph, Predicted phosphatases General function prediction only 154251368 Nonpathogen - hypothetical protein Plav_0912 1 None None None 154253470 Common - seryl-tRNA synthetase Plav_3030 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 154252355 Nonpathogen - hypothetical protein Plav_1907 1 None None None 154252238 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_1787 25 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 154252975 Common - efflux transporter, RND family, MFP subunit Plav_2533 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154252794 Common - hypothetical protein Plav_2349 11 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 154251889 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein Plav_1436 196 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 154250967 Common - ABC transporter related Plav_0511 248 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 154253808 Common - outer membrane efflux protein Plav_3371 57 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154251006 Nonpathogen - hypothetical protein Plav_0550 1 None None None 154251304 Common - AMP-dependent synthetase and ligase Plav_0848 217 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252769 Nonpathogen - putative transcriptional regulator, TetR family Plav_2322 1 COG1309 AcrR, Transcriptional regulator Transcription 154253194 Common - ribosomal protein S5 Plav_2753 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 154251434 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_0978 2 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154253186 Common - ribosomal protein S17 Plav_2745 229 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 154253426 Common - polar amino acid ABC transporter, inner membrane subunit Plav_2986 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 154250698 Common - Leucyl aminopeptidase Plav_0242 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 154251954 Common - Beta-ketoacyl synthase Plav_1502 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253042 Common - molybdopterin binding domain Plav_2601 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 154251895 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_1442 26 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154251887 Common - Succinate dehydrogenase hydrophobic membrane anchor Plav_1434 35 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 154253648 Common - protein of unknown function DUF1467 Plav_3209 12 COG5454 COG5454, Predicted secreted protein Function unknown 154251835 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1382 168 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154252421 Common - inner-membrane translocator Plav_1974 145 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 154250532 Nonpathogen - hypothetical protein Plav_0076 1 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 154253202 Common - ribosomal protein L17 Plav_2761 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 154251939 Common - hypothetical protein Plav_1486 26 None None None 154251041 Common - regulator of ribonuclease activity A Plav_0585 99 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 154253782 Common - Alcohol dehydrogenase GroES domain protein Plav_3345 199 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 154250762 Common - HAD-superfamily hydrolase, subfamily IIB Plav_0306 82 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 154251855 Common - aconitate hydratase 1 Plav_1402 223 COG1048 AcnA, Aconitase A Energy production and conversion 154251283 Common - putative transcriptional regulator, Crp/Fnr family Plav_0827 97 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154252588 Common - pentapeptide repeat protein Plav_2141 61 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 154250757 Common - ribosomal protein L34 Plav_0301 190 None None None 154251633 Common - putative transcriptional regulator Plav_1179 49 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 154251698 Common - transcriptional regulator, XRE family Plav_1245 12 COG1396 HipB, Predicted transcriptional regulators Transcription 154252997 Common - hypothetical protein Plav_2555 24 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 154253226 Common - transcriptional regulator, TetR family Plav_2785 72 COG1309 AcrR, Transcriptional regulator Transcription 154253583 Common - Phosphopyruvate hydratase Plav_3143 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 154252451 Common - Taurine dioxygenase Plav_2004 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154252738 Common - Methyltransferase type 11 Plav_2291 206 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154253366 Common - hypothetical protein Plav_2926 13 None None None 154251643 Common - hypothetical protein Plav_1189 9 None None None 154252543 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Plav_2096 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 154251314 Common - hypothetical protein Plav_0858 23 COG4427 COG4427, Uncharacterized protein conserved in bacteria Function unknown 154251919 Common - ATP synthase F1, epsilon subunit Plav_1466 182 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 154253954 Nonpathogen - hypothetical protein Plav_3522 7 None None None 154250959 Common - proline iminopeptidase Plav_0503 91 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251040 Nonpathogen - hypothetical protein Plav_0584 1 None None None 154252282 Nonpathogen - putative membrane protein of unknown function Plav_1832 9 None None None 154254028 Common - hypothetical protein Plav_3597 59 COG3176 COG3176, Putative hemolysin General function prediction only 154253216 Common - surface presentation of antigens (SPOA) protein Plav_2775 74 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 154250961 Common - Ribonucleoside-diphosphate reductase Plav_0505 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 154253840 Common - hypothetical protein Plav_3404 15 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 154253742 Nonpathogen - hypothetical protein Plav_3304 2 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 154250855 Common - two component transcriptional regulator, winged helix family Plav_0399 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154253899 Common - heavy metal translocating P-type ATPase Plav_3467 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154254016 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Plav_3585 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 154253525 Common - sodium/proline symporter Plav_3085 180 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 154252220 Common - transcriptional regulator, TetR family Plav_1768 149 COG1309 AcrR, Transcriptional regulator Transcription 154252265 Nonpathogen - hypothetical protein Plav_1815 1 None None None 154252524 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Plav_2077 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 154251956 Common - ABC transporter related Plav_1504 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154251816 Common - protein of unknown function DUF1329 Plav_1363 19 None None None 154252439 Common - glycosyl transferase group 1 Plav_1992 137 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154251837 Common - beta-lactamase Plav_1384 58 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 154253963 Common - Cobyrinic acid ac-diamide synthase Plav_3532 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154251276 Common - Methyltransferase type 11 Plav_0820 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154253496 Common - hypothetical protein Plav_3056 32 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 154253956 Common - protein of unknown function DUF736 Plav_3524 27 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154253585 Common - TonB-dependent receptor plug Plav_3145 129 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154251359 Common - phage portal protein, HK97 family Plav_0903 62 COG4695 COG4695, Phage-related protein Function unknown 154250873 Common - NADPH-dependent FMN reductase Plav_0417 27 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 154252225 Common - Rieske (2Fe-2S) domain protein Plav_1773 98 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 154252484 Nonpathogen - hypothetical protein Plav_2037 1 None None None 154251591 Common - short-chain dehydrogenase/reductase SDR Plav_1137 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253732 Common - Leucyltransferase Plav_3294 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 154250715 Common - amino acid carrier protein Plav_0259 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 154251691 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Plav_1238 46 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 154253168 Common - ribosomal protein L10 Plav_2727 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 154251879 Common - aspartate-semialdehyde dehydrogenase Plav_1426 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 154250730 Common - GCN5-related N-acetyltransferase Plav_0274 81 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 154253870 Common - transcriptional regulator, AbrB family Plav_3434 18 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 154253201 Common - DNA-directed RNA polymerase, alpha subunit Plav_2760 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 154251048 Common - isocitrate lyase Plav_0592 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 154252045 Common - protein of unknown function DUF218 Plav_1593 32 COG1434 COG1434, Uncharacterized conserved protein Function unknown 154250743 Common - isoleucyl-tRNA synthetase Plav_0287 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154251614 Common - glucose sorbosone dehydrogenase Plav_1160 118 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 154251998 Common - hypothetical protein Plav_1546 31 COG4420 COG4420, Predicted membrane protein Function unknown 154252005 Common - protein of unknown function DUF559 Plav_1553 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 154252196 Common - PTSINtr with GAF domain, PtsP Plav_1744 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 154253551 Common - peptidase M23B Plav_3111 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154251285 Common - Taurine dioxygenase Plav_0829 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154253948 Common - hypothetical protein Plav_3516 4 None None None 154251313 Common - Citrate (Si)-synthase Plav_0857 192 COG0372 GltA, Citrate synthase Energy production and conversion 154250665 Nonpathogen - hypothetical protein Plav_0209 1 None None None 154252424 Nonpathogen - hypothetical protein Plav_1977 1 None None None 154252730 Common - short chain dehydrogenase Plav_2283 4 None None None 154251476 Common - short-chain dehydrogenase/reductase SDR Plav_1021 222 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154251402 Common - (Glutamate--ammonia-ligase) adenylyltransferase Plav_0946 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 154252612 Common - methyltransferase FkbM family Plav_2165 43 None None None 154251729 Common - Cobyrinic acid ac-diamide synthase Plav_1276 228 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154252017 Common - alpha/beta hydrolase fold Plav_1565 174 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253475 Common - preprotein translocase, YajC subunit Plav_3035 170 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 154251641 Common - Conjugal transfer protein Plav_1187 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 154252642 Common - Exopolysaccharide synthesis ExoD Plav_2195 29 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 154252189 Common - glutaredoxin 3 Plav_1737 139 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 154251134 Common - peptidase M16 domain protein Plav_0678 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 154250770 Common - hypothetical protein Plav_0314 22 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 154253204 Common - bacterioferritin Plav_2763 105 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 154253406 Common - NADH dehydrogenase (quinone) Plav_2966 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 154253817 Common - hypothetical protein Plav_3380 24 None None None 154253287 Nonpathogen - hypothetical protein Plav_2847 1 None None None 154251415 Nonpathogen - hypothetical protein Plav_0959 4 None None None 154253819 Common - Domain of unknown function DUF1845 Plav_3382 22 None None None 154250493 Common - 2OG-Fe(II) oxygenase Plav_0037 46 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 154252290 Common - P-type conjugative transfer protein TrbL Plav_1840 33 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 154251924 Common - protein of unknown function DUF610 YibQ Plav_1471 60 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 154251364 Common - phage conserved hypothetical protein, phiE125 gp8 Plav_0908 20 None None None 154251553 Common - RND efflux system, outer membrane lipoprotein, NodT family Plav_1099 122 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154253531 Common - 2-nitropropane dioxygenase NPD Plav_3091 109 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154251430 Common - chaperone DnaJ domain protein Plav_0974 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154253535 Common - transferase hexapeptide repeat containing protein Plav_3095 204 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 154253304 Common - Uracil-DNA glycosylase superfamily Plav_2864 102 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 154253687 Common - hypothetical protein Plav_3249 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 154251957 Common - ABC-2 type transporter Plav_1505 149 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 154251439 Common - Extradiol ring-cleavage dioxygenase class III protein subunit B Plav_0983 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 154252767 Common - ThiJ/PfpI domain protein Plav_2320 28 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 154250509 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Plav_0053 130 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 154251235 Common - exodeoxyribonuclease VII, small subunit Plav_0779 141 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 154252619 Common - 3'(2'),5'-bisphosphate nucleotidase Plav_2172 181 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 154250764 Common - Alpha,alpha-trehalose-phosphate synthase (UDP-forming) Plav_0308 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 154251081 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Plav_0625 124 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 154253578 Common - dihydrolipoamide dehydrogenase Plav_3138 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154251857 Common - heme exporter protein CcmA Plav_1404 248 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 154250475 Common - plasmid maintenance system antidote protein, XRE family Plav_0019 87 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 154251899 Common - methylmalonate-semialdehyde dehydrogenase Plav_1446 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154252841 Common - VacJ family lipoprotein Plav_2399 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 154252431 Common - GTP-binding protein TypA Plav_1984 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 154253012 Common - flagellar basal-body rod protein FlgB Plav_2570 47 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 154252708 Common - protein of unknown function DUF185 Plav_2261 90 COG1565 COG1565, Uncharacterized conserved protein Function unknown 154253373 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Plav_2933 207 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 154251849 Common - hypothetical protein Plav_1396 30 None None None 154251308 Common - Phytanoyl-CoA dioxygenase Plav_0852 19 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 154253231 Common - peptidase S15 Plav_2790 74 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 154252273 Common - protein of unknown function DUF955 Plav_1823 10 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 154251334 Nonpathogen - hypothetical protein Plav_0878 1 None None None 154253047 Nonpathogen - hypothetical protein Plav_2606 1 None None None 154250608 Common - hypothetical protein Plav_0152 20 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 154253320 Common - TRAP dicarboxylate transporter, DctM subunit Plav_2880 123 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 154252144 Common - peptidase M48 Ste24p Plav_1692 130 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 154253714 Common - penicillin-binding protein, 1A family Plav_3276 203 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 154251378 Nonpathogen - hypothetical protein Plav_0922 1 None None None 154253089 Common - hypothetical protein Plav_2648 19 None None None 154250719 Common - tRNA pseudouridine synthase A Plav_0263 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 154251263 Common - nuclear export factor GLE1 Plav_0807 31 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 154253458 Common - exodeoxyribonuclease III Xth Plav_3018 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 154251052 Common - cytochrome bd ubiquinol oxidase subunit I Plav_0596 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 154252032 Common - methionine biosynthesis protein MetW Plav_1580 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252663 Nonpathogen - hypothetical protein Plav_2216 2 None None None 154253507 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Plav_3067 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 154253352 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Plav_2912 230 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 154253395 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Plav_2955 139 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 154251521 Common - Substrate-binding region of ABC-type glycine betaine transport system Plav_1066 182 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 154253244 Common - Endoribonuclease L-PSP Plav_2803 94 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 154250863 Common - acetylornithine deacetylase (ArgE) Plav_0407 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 154252517 Nonpathogen - protein of unknown function DUF1457 Plav_2070 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154251062 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Plav_0606 138 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 154251423 Common - protein of unknown function DUF899 thioredoxin family protein Plav_0967 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 154252691 Common - cytochrome c1 Plav_2244 81 COG2857 CYT1, Cytochrome c1 Energy production and conversion 154252069 Common - addiction module toxin, RelE/StbE family Plav_1617 32 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 154250692 Common - type II secretion system protein E Plav_0236 166 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 154252083 Common - glutamyl-tRNA synthetase class Ic Plav_1631 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 154253451 Common - Sel1 domain protein repeat-containing protein Plav_3011 80 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154250827 Common - short-chain dehydrogenase/reductase SDR Plav_0371 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253739 Common - beta-Ig-H3/fasciclin Plav_3301 39 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 154252287 Common - putative conjugal transfer TrbD transmembrane protein Plav_1837 25 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 154252213 Common - Rieske (2Fe-2S) domain protein Plav_1761 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 154252981 Common - Methyltransferase type 11 Plav_2539 49 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154253488 Common - hypothetical protein Plav_3048 6 None None None 154253724 Common - hypothetical protein Plav_3286 6 None None None 154250512 Nonpathogen - protein of unknown function DUF1328 Plav_0056 1 COG5487 COG5487, Small integral membrane protein Function unknown 154252917 Common - Helix-turn-helix type 11 domain protein Plav_2475 96 COG2378 COG2378, Predicted transcriptional regulator Transcription 154251706 Common - dephospho-CoA kinase Plav_1253 203 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 154251541 Common - alpha/beta hydrolase fold Plav_1087 131 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251115 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_0659 69 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154251925 Common - carboxyl-terminal protease Plav_1472 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 154252386 Common - Beta-galactosidase Plav_1938 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 154253276 Common - aspartate carbamoyltransferase Plav_2836 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 154253128 Common - major facilitator superfamily MFS_1 Plav_2687 157 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 154251049 Common - malate synthase A Plav_0593 62 COG2225 AceB, Malate synthase Energy production and conversion 154251764 Common - peptidase S16 lon domain protein Plav_1311 79 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 154251075 Common - phosphoribosylamine--glycine ligase Plav_0619 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 154252956 Common - Mammalian cell entry related domain protein Plav_2514 93 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154250522 Common - hypothetical protein Plav_0066 13 COG4655 COG4655, Predicted membrane protein Function unknown 154252656 Common - transcriptional regulator, TetR family Plav_2209 31 COG1309 AcrR, Transcriptional regulator Transcription 154251681 Common - PfkB domain protein Plav_1228 158 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 154253039 Common - Amidase Plav_2598 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154252170 Common - Shikimate kinase Plav_1718 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 154251121 Common - helix-turn-helix- domain containing protein AraC type Plav_0665 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154251074 Common - aminoglycoside phosphotransferase Plav_0618 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 154254002 Common - Dihydrodipicolinate reductase Plav_3571 194 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 154253485 Common - excinuclease ABC, A subunit Plav_3045 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 154252910 Nonpathogen - globin Plav_2468 3 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 154252747 Common - aminotransferase class I and II Plav_2300 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 154252921 Common - cell shape determining protein, MreB/Mrl family Plav_2479 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 154254044 Common - peptidase M22 glycoprotease Plav_3613 59 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 154253567 Common - two component, sigma54 specific, transcriptional regulator, Fis family Plav_3127 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154250925 Common - ThiJ/PfpI domain protein Plav_0469 105 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 154252343 Common - rfaE bifunctional protein Plav_1895 129 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 154251909 Common - dihydrolipoamide dehydrogenase Plav_1456 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154252177 Nonpathogen - protein of unknown function DUF1457 Plav_1725 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154253949 Common - putative methylase/helicase Plav_3517 22 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 154252900 Common - HflK protein Plav_2458 189 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 154253932 Nonpathogen - transcriptional regulator, MarR family Plav_3500 2 COG1846 MarR, Transcriptional regulators Transcription 154252470 Common - response regulator receiver protein Plav_2023 20 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 154250777 Common - hypothetical protein Plav_0321 7 None None None 154251299 Common - hypothetical protein Plav_0843 25 None None None 154252996 Nonpathogen - hypothetical protein Plav_2554 3 None None None 154253695 Common - iron-sulfur cluster assembly accessory protein Plav_3257 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 154252060 Common - Electron transfer flavoprotein alpha/beta-subunit Plav_1608 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 154251576 Common - 17 kDa surface antigen Plav_1122 12 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 154252293 Common - conjugation TrbI family protein Plav_1843 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 154253886 Common - acetate kinase Plav_3453 161 COG0282 ackA, Acetate kinase Energy production and conversion 154250875 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Plav_0419 160 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 154252572 Common - tRNA(Ile)-lysidine synthetase Plav_2125 182 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 154253030 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Plav_2589 168 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 154250906 Common - short-chain dehydrogenase/reductase SDR Plav_0450 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251038 Common - S-adenosylmethionine decarboxylase related Plav_0582 69 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 154251607 Nonpathogen - hypothetical protein Plav_1153 1 None None None 154252830 Common - regulatory protein ArsR Plav_2387 86 COG0640 ArsR, Predicted transcriptional regulators Transcription 154251292 Common - molybdate ABC transporter, inner membrane subunit Plav_0836 223 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 154254025 Common - Mg chelatase, subunit ChlI Plav_3594 197 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 154251153 Common - ATP synthase F0, A subunit Plav_0697 199 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 154252070 Common - beta-lactamase domain protein Plav_1618 213 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154252909 Common - hypothetical protein Plav_2467 14 None None None 154252639 Common - pseudouridine synthase Plav_2192 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 154250577 Common - glutathione S-transferase-like protein Plav_0121 18 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251392 Common - multi-sensor signal transduction histidine kinase Plav_0936 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252968 Common - Methyltransferase type 11 Plav_2526 123 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154250982 Common - translation initiation factor IF-1 Plav_0526 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 154252058 Common - 3-hydroxybutyryl-CoA dehydrogenase Plav_1606 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 154254034 Common - prevent-host-death family protein Plav_3603 25 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 154251743 Common - thioesterase superfamily protein Plav_1290 20 COG0824 FcbC, Predicted thioesterase General function prediction only 154253172 Common - ribosomal protein S12 Plav_2731 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 154251742 Common - two component transcriptional regulator, winged helix family Plav_1289 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154250702 Common - binding-protein-dependent transport systems inner membrane component Plav_0246 219 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 154251656 Common - hypothetical protein Plav_1202 16 None None None 154251485 Nonpathogen - hypothetical protein Plav_1030 1 None None None 154250585 Common - hypothetical protein Plav_0129 3 None None None 154253327 Common - MotA/TolQ/ExbB proton channel Plav_2887 102 COG1291 MotA, Flagellar motor component Cell motility and secretion 154250635 Common - extracellular solute-binding protein family 1 Plav_0179 105 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 154253655 Common - NADH-ubiquinone oxidoreductase chain 4L Plav_3216 137 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 154251749 Common - aminotransferase class-III Plav_1296 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 154253809 Nonpathogen - hypothetical protein Plav_3372 1 None None None 154251650 Common - TRAG family protein Plav_1196 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 154252356 Common - O-antigen polymerase Plav_1908 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 154253253 Nonpathogen - hypothetical protein Plav_2812 7 None None None 154253108 Common - protein of unknown function DUF37 Plav_2667 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 154253251 Nonpathogen - hypothetical protein Plav_2810 1 None None None 154251184 Common - glycyl-tRNA synthetase, beta subunit Plav_0728 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 154251636 Common - phage transcriptional regulator, AlpA Plav_1182 26 COG3311 AlpA, Predicted transcriptional regulator Transcription 154253193 Common - ribosomal protein L18 Plav_2752 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 154251221 Nonpathogen - hypothetical protein Plav_0765 1 None None None 154251027 Common - drug resistance transporter, Bcr/CflA subfamily Plav_0571 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251841 Common - transcriptional coactivator/pterin dehydratase Plav_1388 98 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 154251507 Common - phospholipase/Carboxylesterase Plav_1052 20 COG0400 COG0400, Predicted esterase General function prediction only 154253989 Common - hypothetical protein Plav_3558 22 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 154251906 Common - succinyl-CoA synthetase, alpha subunit Plav_1453 212 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 154251868 Common - Diaminopimelate epimerase Plav_1415 195 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 154251861 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Plav_1408 151 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 154253411 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Plav_2971 94 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 154251464 Common - pseudoazurin Plav_1008 31 COG3794 PetE, Plastocyanin Energy production and conversion 154252129 Common - alpha/beta hydrolase fold Plav_1677 89 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251575 Common - Glu/Leu/Phe/Val dehydrogenase Plav_1121 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 154252115 Common - short-chain dehydrogenase/reductase SDR Plav_1663 215 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253842 Common - hypothetical protein Plav_3406 5 COG4469 CoiA, Competence protein General function prediction only 154250735 Nonpathogen - hypothetical protein Plav_0279 1 None None None 154251251 Common - short-chain dehydrogenase/reductase SDR Plav_0795 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253332 Nonpathogen - Biopolymer transport protein ExbD/TolR Plav_2892 1 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154252208 Nonpathogen - hypothetical protein Plav_1756 1 None None None 154251294 Common - Taurine dioxygenase Plav_0838 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154253616 Common - molybdenum cofactor synthesis domain Plav_3177 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 154253976 Common - P-type conjugative transfer protein TrbJ Plav_3545 22 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 154252271 Common - hypothetical protein Plav_1821 28 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 154250794 Nonpathogen - hypothetical protein Plav_0338 4 COG1059 COG1059, Thermostable 8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 154252202 Common - MOSC domain containing protein Plav_1750 30 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 154253678 Common - acetyl-CoA acetyltransferase Plav_3240 14 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154250570 Common - PTS system fructose subfamily IIA component Plav_0114 97 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 154250617 Common - aminotransferase class-III Plav_0161 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 154253520 Common - protein of unknown function DUF339 Plav_3080 40 COG2938 COG2938, Uncharacterized conserved protein Function unknown 154251530 Common - thioesterase superfamily protein Plav_1075 13 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154253826 Common - heavy metal translocating P-type ATPase Plav_3390 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154251935 Common - ribosomal protein L27 Plav_1482 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 154253767 Nonpathogen - hypothetical protein Plav_3330 6 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 154253343 Common - Peptidoglycan-binding domain 1 protein Plav_2903 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 154253358 Common - UspA domain protein Plav_2918 92 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154252550 Common - Sel1 domain protein repeat-containing protein Plav_2103 96 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154250686 Nonpathogen - Flp/Fap pilin component Plav_0230 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 154250558 Common - Resolvase domain Plav_0102 89 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 154252491 Common - Ion transport protein Plav_2044 26 None None None 154250554 Common - CRISPR-associated protein Cas1 Plav_0098 25 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 154250674 Common - ribosomal protein L35 Plav_0218 143 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 154252532 Common - Alcohol dehydrogenase GroES domain protein Plav_2085 176 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 154253999 Common - endonuclease III Plav_3568 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 154251542 Nonpathogen - hypothetical protein Plav_1088 2 None None None 154251513 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Plav_1058 100 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 154251562 Common - helix-turn-helix- domain containing protein AraC type Plav_1108 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154251306 Common - sodium/hydrogen exchanger Plav_0850 115 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 154251753 Common - cell divisionFtsK/SpoIIIE Plav_1300 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 154252498 Common - OmpA/MotB domain protein Plav_2051 105 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154252862 Common - cell division protein FtsW Plav_2420 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 154251207 Common - Usg family protein Plav_0751 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 154250501 Common - major facilitator superfamily MFS_1 Plav_0045 176 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154253772 Common - beta-lactamase domain protein Plav_3335 25 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154253169 Common - ribosomal protein L7/L12 Plav_2728 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 154250748 Common - Glucose-6-phosphate isomerase Plav_0292 154 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 154251104 Common - PAS/PAC sensor signal transduction histidine kinase Plav_0648 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154250706 Common - cytochrome c class I Plav_0250 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 154251106 Common - fatty acid desaturase Plav_0650 25 COG3239 DesA, Fatty acid desaturase Lipid metabolism 154253079 Common - peptidylprolyl isomerase FKBP-type Plav_2638 165 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 154252976 Common - protein of unknown function DUF214 Plav_2534 221 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 154253195 Common - ribosomal protein L30 Plav_2754 106 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 154251494 Common - RES domain protein Plav_1039 14 None None None 154250622 Common - aldehyde dehydrogenase Plav_0166 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154253780 Common - dimethyladenosine transferase Plav_3343 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 154252609 Nonpathogen - putative transcriptional regulator Plav_2162 15 None None None 154253443 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Plav_3003 163 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 154252777 Nonpathogen - hypothetical protein Plav_2330 1 None None None 154253637 Common - protein of unknown function DUF262 Plav_3198 25 None None None 154253594 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Plav_3155 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 154253187 Common - ribosomal protein L14 Plav_2746 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 154252562 Common - crossover junction endodeoxyribonuclease RuvC Plav_2115 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 154251274 Common - ABC transporter related Plav_0818 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 154252105 Common - hypothetical protein Plav_1653 17 None None None 154253659 Common - NADH-quinone oxidoreductase, chain G Plav_3220 192 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 154253106 Common - cysteinyl-tRNA synthetase Plav_2665 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154250583 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Plav_0127 243 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 154251448 Common - isochorismatase hydrolase Plav_0992 117 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 154252127 Common - alpha/beta hydrolase fold Plav_1675 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252158 Common - ribosomal protein L28 Plav_1706 142 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 154251213 Common - hypothetical protein Plav_0757 15 COG5451 COG5451, Predicted secreted protein Function unknown 154253645 Common - hypothetical protein Plav_3206 5 None None None 154253835 Common - hypothetical protein Plav_3399 21 None None None 154253787 Common - C-methyltransferase Plav_3350 45 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154251750 Common - Glutamate--putrescine ligase Plav_1297 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154252625 Nonpathogen - hypothetical protein Plav_2178 2 None None None 154252433 Common - hypothetical protein Plav_1986 68 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 154253029 Common - phosphoribosylformylglycinamidine synthase, purS Plav_2588 117 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 154251628 Common - hypothetical protein Plav_1174 6 None None None 154252796 Common - hypothetical protein Plav_2351 25 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 154253603 Nonpathogen - hypothetical protein Plav_3164 10 None None None 154252686 Common - hypothetical protein Plav_2239 2 None None None 154252807 Common - short-chain dehydrogenase/reductase SDR Plav_2362 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252040 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_1588 19 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 154253070 Common - hypothetical protein Plav_2629 9 None None None 154253091 Common - small multidrug resistance protein Plav_2650 116 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 154251539 Common - multi-sensor signal transduction histidine kinase Plav_1084 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154253143 Common - CutA1 divalent ion tolerance protein Plav_2702 119 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 154251016 Common - glycosyl transferase family 2 Plav_0560 134 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 154251056 Common - ATP phosphoribosyltransferase Plav_0600 175 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 154251384 Common - two component transcriptional regulator, winged helix family Plav_0928 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154252943 Common - aminoglycoside phosphotransferase Plav_2501 56 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 154253156 Nonpathogen - hypothetical protein Plav_2715 1 None None None 154253173 Common - ribosomal protein S7 Plav_2732 224 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 154253146 Common - FAD linked oxidase domain protein Plav_2705 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 154251324 Common - transcriptional regulator, XRE family Plav_0868 13 COG1396 HipB, Predicted transcriptional regulators Transcription 154253453 Common - MlrC domain protein Plav_3013 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 154252415 Nonpathogen - Hpt domain protein Plav_1967 6 None None None 154251316 Nonpathogen - hypothetical protein Plav_0860 1 None None None 154253777 Common - Organic solvent tolerance protein Plav_3340 114 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 154250604 Common - signal peptide peptidase SppA, 36K type Plav_0148 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154253339 Common - Enoyl-CoA hydratase/isomerase Plav_2899 160 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154250645 Common - protein of unknown function DUF1150 Plav_0189 12 COG5568 COG5568, Uncharacterized small protein Function unknown 154252666 Common - hypothetical protein Plav_2219 5 None None None 154252137 Common - Enoyl-CoA hydratase/isomerase Plav_1685 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253628 Common - putative membrane-associated zinc metalloprotease Plav_3189 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 154253730 Common - acetyl-CoA carboxylase, biotin carboxylase Plav_3292 232 COG0439 AccC, Biotin carboxylase Lipid metabolism 154251180 Common - O-methyltransferase Plav_0724 53 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 154250829 Common - TonB family protein Plav_0373 22 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154252891 Common - Dihydrofolate reductase Plav_2449 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 154250820 Nonpathogen - hypothetical protein Plav_0364 1 None None None 154251452 Common - MotA/TolQ/ExbB proton channel Plav_0996 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154252782 Nonpathogen - hypothetical protein Plav_2337 3 None None None 154250804 Common - blue (type 1) copper domain protein Plav_0348 27 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 154253068 Common - short-chain dehydrogenase/reductase SDR Plav_2627 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253992 Common - hypothetical protein Plav_3561 6 None None None 154250466 Common - protein of unknown function DUF45 Plav_0010 150 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 154253922 Common - transcriptional regulator, HxlR family Plav_3490 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 154252446 Common - efflux transporter, RND family, MFP subunit Plav_1999 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154251988 Common - efflux transporter, RND family, MFP subunit Plav_1536 144 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154252683 Common - NUDIX hydrolase Plav_2236 117 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 154253468 Common - twin-arginine translocation protein, TatB subunit Plav_3028 42 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 154252837 Common - short-chain dehydrogenase/reductase SDR Plav_2395 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252301 Nonpathogen - transcriptional regulator, MarR family Plav_1851 8 COG1846 MarR, Transcriptional regulators Transcription 154251094 Common - hypothetical protein Plav_0638 6 None None None 154250810 Common - efflux transporter, RND family, MFP subunit Plav_0354 144 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154251471 Common - Potassium-transporting ATPase Plav_1015 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 154253543 Nonpathogen - hypothetical protein Plav_3103 1 None None None 154253316 Common - DNA repair protein RecO Plav_2876 39 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 154253116 Nonpathogen - hypothetical protein Plav_2675 1 None None None 154250845 Common - alpha/beta hydrolase fold Plav_0389 171 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252295 Common - protein of unknown function DUF736 Plav_1845 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154253045 Common - choline dehydrogenase Plav_2604 97 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 154252267 Common - protein of unknown function DUF736 Plav_1817 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154253737 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Plav_3299 181 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 154252003 Common - extracellular solute-binding protein family 1 Plav_1551 134 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 154253708 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Plav_3270 213 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154252469 Common - alpha/beta hydrolase fold Plav_2022 66 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253701 Common - aminotransferase class V Plav_3263 235 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 154252478 Common - Hydroxypyruvate reductase Plav_2031 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 154251559 Common - 2-isopropylmalate synthase/homocitrate synthase family protein Plav_1105 212 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 154253850 Common - hypothetical protein Plav_3414 33 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 154252079 Nonpathogen - hypothetical protein Plav_1627 1 None None None 154251148 Common - protein of unknown function DUF925 Plav_0692 22 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 154251548 Common - ribose 5-phosphate isomerase Plav_1094 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 154253694 Common - Enoyl-CoA hydratase/isomerase Plav_3256 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253560 Common - major facilitator superfamily MFS_1 Plav_3120 93 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154251178 Common - Polyprenyl synthetase Plav_0722 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 154251734 Common - hypothetical protein Plav_1281 24 None None None 154251722 Common - GCN5-related N-acetyltransferase Plav_1269 102 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 154251811 Common - histidine kinase Plav_1358 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154251885 Common - thioesterase superfamily protein Plav_1432 63 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154252595 Nonpathogen - hypothetical protein Plav_2148 2 None None None 154252869 Common - cell division protein FtsZ Plav_2427 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 154253052 Common - major facilitator superfamily MFS_1 Plav_2611 90 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154251526 Common - regulatory protein ArsR Plav_1071 63 COG0640 ArsR, Predicted transcriptional regulators Transcription 154251715 Common - alpha/beta hydrolase fold Plav_1262 35 COG2267 PldB, Lysophospholipase Lipid metabolism 154253266 Nonpathogen - hypothetical protein Plav_2826 1 None None None 154252311 Nonpathogen - hypothetical protein Plav_1861 2 None None None 154253569 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Plav_3129 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154251581 Common - hypothetical protein Plav_1127 14 None None None 154250957 Common - short-chain dehydrogenase/reductase SDR Plav_0501 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251738 Common - alanine racemase domain protein Plav_1285 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 154250891 Common - putative phage repressor Plav_0435 32 COG2932 COG2932, Predicted transcriptional regulator Transcription 154250658 Common - NAD-dependent epimerase/dehydratase Plav_0202 128 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154253763 Common - Polyphosphate kinase Plav_3326 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 154251794 Common - protein of unknown function DUF55 Plav_1341 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 154251022 Common - Enoyl-CoA hydratase/isomerase Plav_0566 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252789 Common - type I site-specific deoxyribonuclease, HsdR family Plav_2344 138 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 154251499 Common - ATPase-like protein Plav_1044 81 COG0433 COG0433, Predicted ATPase General function prediction only 154252314 Common - protein of unknown function DUF344 Plav_1864 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 154252351 Common - polysaccharide export protein Plav_1903 115 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 154252856 Common - hypothetical protein Plav_2414 28 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 154251410 Common - FAD dependent oxidoreductase Plav_0954 104 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 154251739 Common - hypothetical protein Plav_1286 40 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 154250831 Common - TonB-system energizer ExbB type-1 Plav_0375 123 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154251950 Nonpathogen - hypothetical protein Plav_1498 1 None None None 154252935 Common - Methyltransferase type 11 Plav_2493 151 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154251707 Common - shikimate 5-dehydrogenase Plav_1254 214 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 154252030 Common - Hydroxyacylglutathione hydrolase Plav_1578 201 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154253505 Common - UDP-glucose 4-epimerase Plav_3065 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 154250935 Common - alpha/beta hydrolase fold Plav_0479 32 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154250898 Nonpathogen - protein of unknown function DUF1457 Plav_0442 2 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154250590 Common - protein of unknown function UPF0079 Plav_0134 189 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 154252693 Common - adenine phosphoribosyltransferase Plav_2246 176 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 154253606 Nonpathogen - hypothetical protein Plav_3167 1 None None None 154251917 Common - ATP synthase F1, gamma subunit Plav_1464 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 154251584 Common - poly(3-hydroxyalkanoate) depolymerase Plav_1130 121 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253220 Common - Kelch repeat protein Plav_2779 30 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 154252396 Common - Glutathione S-transferase domain Plav_1948 23 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253082 Common - transglutaminase family protein cysteine peptidase BTLCP Plav_2641 20 COG3672 COG3672, Predicted periplasmic protein Function unknown 154252722 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Plav_2275 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 154251492 Common - MaoC domain protein dehydratase Plav_1037 11 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154252164 Common - cobalt chelatase, pCobT subunit Plav_1712 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 154250722 Common - succinyl-diaminopimelate desuccinylase Plav_0266 216 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 154251671 Common - putative methylase/helicase Plav_1218 22 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 154253798 Common - ribosomal protein S6 Plav_3361 205 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 154254015 Common - Extracellular ligand-binding receptor Plav_3584 45 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 154253420 Common - Sel1 domain protein repeat-containing protein Plav_2980 99 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154251003 Nonpathogen - hypothetical protein Plav_0547 1 None None None 154252426 Common - Propionyl-CoA carboxylase Plav_1979 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 154253513 Nonpathogen - protein of unknown function DUF1457 Plav_3073 2 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154250950 Common - acetyl-CoA acetyltransferase Plav_0494 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253753 Common - Phytanoyl-CoA dioxygenase Plav_3316 18 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 154251818 Common - Enoyl-CoA hydratase/isomerase Plav_1365 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253662 Common - NADH dehydrogenase I, D subunit Plav_3223 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 154252029 Common - protein of unknown function DUF985 Plav_1577 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 154252851 Common - protein of unknown function DUF6 transmembrane Plav_2409 115 COG2510 COG2510, Predicted membrane protein Function unknown 154252324 Common - MtN3 and saliva related transmembrane protein Plav_1876 26 COG4095 COG4095, Uncharacterized conserved protein Function unknown 154250650 Common - Cell envelope biogenesis YhbN Plav_0194 38 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 154251373 Common - hypothetical protein Plav_0917 29 COG5449 COG5449, Uncharacterized conserved protein Function unknown 154251343 Nonpathogen - hypothetical protein Plav_0887 2 None None None 154251550 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Plav_1096 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 154250632 Common - efflux transporter, RND family, MFP subunit Plav_0176 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154253498 Common - GreA/GreB family elongation factor Plav_3058 63 COG0782 GreA, Transcription elongation factor Transcription 154252578 Common - phosphoglucosamine mutase Plav_2131 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 154250798 Nonpathogen - hypothetical protein Plav_0342 11 COG0433 COG0433, Predicted ATPase General function prediction only 154252150 Common - helicase domain protein Plav_1698 64 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 154250547 Common - putative transcriptional regulator, MerR family Plav_0091 108 COG0789 SoxR, Predicted transcriptional regulators Transcription 154250518 Common - hypothetical protein Plav_0062 20 None None None 154252035 Common - histidinol-phosphate aminotransferase Plav_1583 240 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 154252582 Common - Lysine exporter protein (LYSE/YGGA) Plav_2135 40 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 154251248 Common - hypothetical protein Plav_0792 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 154250971 Common - tRNA/rRNA methyltransferase (SpoU) Plav_0515 39 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 154252015 Common - glutamine amidotransferase of anthranilate synthase Plav_1563 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 154250484 Common - Sterol desaturase Plav_0028 70 COG3000 ERG3, Sterol desaturase Lipid metabolism 154253491 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Plav_3051 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 154254065 Common - short-chain dehydrogenase/reductase SDR Plav_3634 210 COG0623 FabI, Enoyl- acyl-carrier-protein 154251621 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Plav_1167 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 154253872 Nonpathogen - hypothetical protein Plav_3436 1 None None None 154251975 Common - peptide methionine sulfoxide reductase Plav_1523 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 154250915 Common - TRAP dicarboxylate transporter- DctP subunit Plav_0459 88 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154252231 Common - thioesterase superfamily protein Plav_1780 72 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251033 Common - Taurine catabolism dioxygenase TauD/TfdA Plav_0577 10 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154253463 Common - Sporulation domain protein Plav_3023 21 None None None 154253054 Common - sodium:galactoside symporter family protein Plav_2613 91 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154252205 Nonpathogen - hypothetical protein Plav_1753 1 None None None 154253227 Common - Propionyl-CoA carboxylase Plav_2786 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 154250917 Common - putative transcriptional regulator, MerR family Plav_0461 103 COG0789 SoxR, Predicted transcriptional regulators Transcription 154253427 Common - ABC transporter related Plav_2987 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 154254052 Common - apolipoprotein N-acyltransferase Plav_3621 160 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 154253214 Nonpathogen - hypothetical protein Plav_2773 2 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 154251218 Common - L-lactate dehydrogenase (cytochrome) Plav_0762 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 154252455 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_2008 4 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 154253301 Common - Lytic transglycosylase catalytic Plav_2861 161 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154252366 Common - O-antigen polymerase Plav_1918 2 None None None 154252395 Common - acyltransferase 3 Plav_1947 98 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 154251781 Nonpathogen - protein of unknown function DUF1674 Plav_1328 1 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 154251039 Common - spermidine synthase Plav_0583 115 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 154251961 Common - hypothetical protein Plav_1509 16 None None None 154251777 Common - Methyltransferase type 11 Plav_1324 86 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154253622 Common - protein of unknown function DUF1009 Plav_3183 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 154250491 Common - hypothetical protein Plav_0035 15 None None None 154251573 Common - integral membrane sensor signal transduction histidine kinase Plav_1119 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252526 Common - diguanylate cyclase Plav_2079 160 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 154252174 Nonpathogen - hypothetical protein Plav_1722 6 None None None 154253034 Common - Quinoprotein glucose dehydrogenase Plav_2593 60 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 154251859 Common - heme exporter protein CcmC Plav_1406 126 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 154251483 Common - Enoyl-CoA hydratase/isomerase Plav_1028 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154251555 Common - efflux transporter, RND family, MFP subunit Plav_1101 178 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154250782 Nonpathogen - hypothetical protein Plav_0326 1 None None None 154253413 Common - cation antiporter Plav_2973 19 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 154253533 Common - extracellular solute-binding protein family 5 Plav_3093 153 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 154253890 Common - hypothetical protein Plav_3457 33 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 154251991 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_1539 37 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 154251054 Common - histidyl-tRNA synthetase Plav_0598 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154251437 Common - helix-turn-helix- domain containing protein AraC type Plav_0981 80 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 154251390 Common - 1-aminocyclopropane-1-carboxylate deaminase Plav_0934 59 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 154252227 Common - Enoyl-CoA hydratase/isomerase Plav_1776 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253849 Common - hypothetical protein Plav_3413 21 None None None 154251599 Common - carbamate kinase Plav_1145 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 154252306 Common - monofunctional biosynthetic peptidoglycan transglycosylase Plav_1856 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 154254011 Common - ribonuclease PH Plav_3580 188 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 154251661 Common - hypothetical protein Plav_1208 13 None None None 154250498 Nonpathogen - hypothetical protein Plav_0042 1 None None None 154253537 Common - NADH:flavin oxidoreductase/NADH oxidase Plav_3097 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 154253565 Common - aminotransferase class IV Plav_3125 186 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 154251873 Common - 16S rRNA processing protein RimM Plav_1420 174 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 154251083 Common - ABC transporter related Plav_0627 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 154252542 Common - ribosomal protein L31 Plav_2095 118 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 154251654 Common - conjugal transfer protein precursor Plav_1200 28 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154250785 Common - phosphoribosyltransferase-like protein Plav_0329 13 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 154253397 Common - protein of unknown function DUF182 Plav_2957 110 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 154251012 Common - sodium:neurotransmitter symporter Plav_0556 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 154253882 Common - acetoacetyl-CoA reductase Plav_3449 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253716 Common - ribonuclease, Rne/Rng family Plav_3278 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 154252249 Common - regulatory protein IclR Plav_1798 80 COG1414 IclR, Transcriptional regulator Transcription 154251863 Common - NUDIX hydrolase Plav_1410 53 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 154250717 Common - peptide deformylase Plav_0261 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 154252181 Common - major facilitator superfamily MFS_1 Plav_1729 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251571 Common - hypothetical protein Plav_1117 61 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 154253010 Common - flagellar biosynthetic protein FliP Plav_2568 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 154251783 Common - nuclease (SNase domain protein) Plav_1330 13 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 154252551 Common - thiamine-phosphate pyrophosphorylase Plav_2104 202 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 154250606 Common - cytidylate kinase Plav_0150 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 154251959 Common - transcriptional regulator, TetR family Plav_1507 48 COG1309 AcrR, Transcriptional regulator Transcription 154251332 Common - hypothetical protein Plav_0876 21 None None None 154251944 Common - AMP-dependent synthetase and ligase Plav_1491 168 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154251908 Common - 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase Plav_1455 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 154253951 Common - hypothetical protein Plav_3519 20 None None None 154253680 Common - aminotransferase class I and II Plav_3242 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 154253218 Common - phosphoadenosine phosphosulfate reductase Plav_2777 150 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 154254030 Common - DNA mismatch repair protein MutS Plav_3599 198 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 154250666 Common - luciferase family protein Plav_0210 106 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154253726 Common - thiazole biosynthesis family protein Plav_3288 170 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 154252819 Common - aldehyde dehydrogenase Plav_2376 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154253643 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Plav_3204 161 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 154252706 Nonpathogen - hypothetical protein Plav_2259 2 None None None 154250887 Common - integral membrane sensor signal transduction histidine kinase Plav_0431 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253728 Common - 3-dehydroquinate dehydratase, type II Plav_3290 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 154253815 Common - hypothetical protein Plav_3378 10 None None None 154251767 Common - YbaK/prolyl-tRNA synthetase associated region Plav_1314 30 COG3760 COG3760, Uncharacterized conserved protein Function unknown 154252510 Common - GCN5-related N-acetyltransferase Plav_2063 52 COG0456 RimI, Acetyltransferases General function prediction only 154253905 Common - Cyclopropane-fatty-acyl-phospholipid synthase Plav_3473 141 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 154251421 Common - acyl-CoA dehydrogenase domain protein Plav_0965 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252187 Common - Methyltransferase type 11 Plav_1735 95 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154250537 Nonpathogen - hypothetical protein Plav_0081 1 None None None 154250628 Common - transcriptional regulator, PadR-like family Plav_0172 40 COG1695 COG1695, Predicted transcriptional regulators Transcription 154253942 Common - Domain of unknown function DUF1814 Plav_3510 30 COG2253 COG2253, Uncharacterized conserved protein Function unknown 154254005 Common - chaperone protein DnaK Plav_3574 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 154253668 Common - ATP-dependent protease La Plav_3230 228 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 154251865 Common - intracellular septation protein A Plav_1412 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 154252574 Common - ferredoxin Plav_2127 57 COG0633 Fdx, Ferredoxin Energy production and conversion 154253571 Common - putative TIM-barrel protein, nifR3 family Plav_3131 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 154250713 Nonpathogen - hypothetical protein Plav_0257 7 None None None 154251064 Common - Glycine hydroxymethyltransferase Plav_0608 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 154253587 Common - exsB protein Plav_3148 172 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 154251914 Nonpathogen - hypothetical protein Plav_1461 1 None None None 154254000 Common - hypothetical protein Plav_3569 27 COG5488 COG5488, Integral membrane protein Function unknown 154250871 Common - hypothetical protein Plav_0415 21 None None None 154252983 Common - ATPase associated with various cellular activities AAA_5 Plav_2541 110 COG0714 COG0714, MoxR-like ATPases General function prediction only 154250857 Common - ABC-2 type transporter Plav_0401 142 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 154252623 Common - flagellar export protein FliJ Plav_2176 17 None None None 154252846 Common - transcriptional regulator, HxlR family Plav_2404 52 COG1733 COG1733, Predicted transcriptional regulators Transcription 154252422 Common - ABC transporter related Plav_1975 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 154251839 Common - protein of unknown function DUF1232 Plav_1386 47 COG3339 COG3339, Uncharacterized conserved protein Function unknown 154252882 Common - secretion protein HlyD family protein Plav_2440 58 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154252966 Common - hypothetical protein Plav_2524 18 None None None 154250948 Common - thioesterase superfamily protein Plav_0492 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251413 Common - aminopeptidase N Plav_0957 156 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 154251966 Common - band 7 protein Plav_1514 203 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 154253553 Common - methionyl-tRNA synthetase Plav_3113 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154252584 Common - phosphoserine aminotransferase Plav_2137 65 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 154252690 Common - Cytochrome b/b6 domain Plav_2243 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 154250613 Common - MaoC domain protein dehydratase Plav_0157 34 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154252549 Common - translation elongation factor P Plav_2102 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 154251095 Common - Enoyl-CoA hydratase/isomerase Plav_0639 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252770 Common - hypothetical protein Plav_2323 6 None None None 154254049 Common - PhoH family protein Plav_3618 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 154253958 Common - transcriptional regulator, XRE family Plav_3526 13 None None None 154251287 Common - beta-lactamase Plav_0831 141 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 154251318 Common - ABC transporter related Plav_0862 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154252810 Common - hypothetical protein Plav_2367 5 None None None 154251796 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Plav_1343 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 154252222 Common - naphthoate synthase Plav_1770 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 154251474 Common - major facilitator superfamily MFS_1 Plav_1019 40 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154252162 Common - major facilitator superfamily MFS_1 Plav_1710 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154252019 Common - Enoyl-CoA hydratase/isomerase Plav_1567 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154251870 Common - CinA domain protein Plav_1417 43 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 154252280 Common - hypothetical protein Plav_1830 9 None None None 154253650 Common - beta-lactamase domain protein Plav_3211 153 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 154251659 Common - putative transcriptional regulator Plav_1205 24 None None None 154251747 Common - exodeoxyribonuclease III Xth Plav_1294 193 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 154252640 Common - SlyX family protein Plav_2193 31 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 154250469 Common - 2-isopropylmalate synthase Plav_0013 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 154251400 Common - two component transcriptional regulator, winged helix family Plav_0944 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154250741 Common - Excinuclease ABC C subunit domain protein Plav_0285 46 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 154251989 Common - transcriptional regulator, TetR family Plav_1537 124 COG1309 AcrR, Transcriptional regulator Transcription 154254027 Common - major facilitator superfamily MFS_1 Plav_3596 101 None None None 154252191 Common - protein of unknown function DUF1178 Plav_1739 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 154253928 Nonpathogen - hypothetical protein Plav_3496 1 None None None 154251046 Nonpathogen - Parallel beta-helix repeat Plav_0590 4 None None None 154251801 Common - putative metalloendopeptidase, glycoprotease family Plav_1348 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 154252482 Common - alpha/beta hydrolase fold Plav_2035 50 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253936 Common - regulatory protein ArsR Plav_3504 93 COG0640 ArsR, Predicted transcriptional regulators Transcription 154250908 Common - MscS Mechanosensitive ion channel Plav_0452 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154252587 Nonpathogen - protein of unknown function DUF1457 Plav_2140 2 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252832 Nonpathogen - hypothetical protein Plav_2389 3 None None None 154253802 Nonpathogen - hypothetical protein Plav_3365 3 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 154252820 Common - potassium efflux system protein Plav_2377 187 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 154251609 Common - exporters of the RND superfamily Plav_1155 42 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 154253703 Common - hypothetical protein Plav_3265 89 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 154253027 Common - phosphoribosylformylglycinamidine synthase II Plav_2586 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 154251215 Nonpathogen - hypothetical protein Plav_0759 4 None None None 154251740 Common - hypothetical protein Plav_1287 4 None None None 154254037 Common - two component transcriptional regulator, LuxR family Plav_3606 173 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154251808 Nonpathogen - hypothetical protein Plav_1355 1 None None None 154252389 Common - protein of unknown function DUF403 Plav_1941 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 154252955 Common - ABC transporter related Plav_2513 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 154254073 Common - protein of unknown function DUF1058 Plav_3642 46 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 154251237 Common - deoxyxylulose-5-phosphate synthase Plav_0781 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 154251025 Common - hypothetical protein Plav_0569 36 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 154252319 Common - protein of unknown function DUF1365 Plav_1870 62 COG3496 COG3496, Uncharacterized conserved protein Function unknown 154252602 Nonpathogen - putative ketosteroid isomerase-related protein Plav_2155 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 154251890 Nonpathogen - hypothetical protein Plav_1437 1 None None None 154252630 Common - flagellar motor switch protein FliG Plav_2183 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 154251223 Common - protein of unknown function DUF159 Plav_0767 111 COG2135 COG2135, Uncharacterized conserved protein Function unknown 154253322 Common - TRAP dicarboxylate transporter- DctP subunit Plav_2882 95 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154253673 Common - trigger factor Plav_3235 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 154253456 Common - Beta-lactamase Plav_3016 38 COG2602 COG2602, Beta-lactamase class D Defense mechanisms 154251398 Common - cytochrome C biogenesis protein Plav_0942 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 154251688 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Plav_1235 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 154252661 Common - response regulator receiver protein Plav_2214 218 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 154251986 Common - putative exporter of RND superfamily Plav_1534 127 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 154251630 Common - helicase domain protein Plav_1176 229 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 154252848 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_2406 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154250579 Common - (2Fe-2S)-binding domain protein Plav_0123 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 154251182 Nonpathogen - hypothetical protein Plav_0726 1 None None None 154252477 Common - pyruvate kinase Plav_2030 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 154253061 Common - Enoyl-CoA hydratase/isomerase Plav_2620 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252951 Common - Mandelate racemase/muconate lactonizing protein Plav_2509 114 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 154253580 Common - Transketolase central region Plav_3140 219 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 154252354 Common - Non-specific protein-tyrosine kinase Plav_1906 134 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 154250984 Common - ribonuclease, Rne/Rng family Plav_0528 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 154251241 Common - Chorismate synthase Plav_0785 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 154252681 Common - ATPase associated with various cellular activities AAA_3 Plav_2234 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 154253416 Common - ETC complex I subunit conserved region Plav_2976 37 None None None 154250551 Common - aminotransferase class I and II Plav_0095 140 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 154252991 Nonpathogen - flagellar FlaF family protein Plav_2549 12 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 154253246 Common - diguanylate cyclase Plav_2805 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 154253657 Common - NADH-quinone oxidoreductase, chain I Plav_3218 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 154252974 Common - hypothetical protein Plav_2532 2 None None None 154251462 Common - NnrS family protein Plav_1006 57 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 154254018 Common - transport-associated Plav_3587 72 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 154253006 Common - flagellar motor switch protein FliM Plav_2564 106 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 154251509 Common - hypothetical protein Plav_1054 52 COG3577 COG3577, Predicted aspartyl protease General function prediction only 154251072 Common - 6-phosphofructokinase Plav_0616 148 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 154253329 Common - transcriptional regulator, MarR family Plav_2889 40 COG1846 MarR, Transcriptional regulators Transcription 154251169 Common - molybdenum cofactor biosynthesis protein B Plav_0713 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 154252404 Common - VWA containing CoxE family protein Plav_1956 45 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 154253379 Common - N-acetyl-gamma-glutamyl-phosphate reductase Plav_2939 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 154251065 Common - acyl-CoA dehydrogenase domain protein Plav_0609 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154250507 Common - signal transduction histidine kinase Plav_0051 74 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 154252253 Common - Alcohol dehydrogenase GroES domain protein Plav_1802 211 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 154252919 Common - Na+/Ca+ antiporter, CaCA family Plav_2477 120 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 154251388 Common - putative cold-shock DNA-binding domain protein Plav_0932 178 COG1278 CspC, Cold shock proteins Transcription 154252718 Common - branched-chain amino acid aminotransferase Plav_2271 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 154250694 Common - type II secretion system protein Plav_0238 75 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 154251704 Common - DNA polymerase III, epsilon subunit Plav_1251 193 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 154252508 Nonpathogen - hypothetical protein Plav_2061 1 None None None 154254040 Common - hypothetical protein Plav_3609 25 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 154251110 Common - NUDIX hydrolase Plav_0654 22 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 154251766 Nonpathogen - hypothetical protein Plav_1313 2 None None None 154252113 Common - AMP-dependent synthetase and ligase Plav_1661 207 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253314 Common - Ribonuclease III Plav_2874 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 154253049 Common - putative transcriptional regulator, Crp/Fnr family Plav_2608 137 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154252077 Common - methylmalonyl-CoA mutase, large subunit Plav_1625 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 154252285 Common - P-type conjugative transfer ATPase TrbB Plav_1835 227 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 154251280 Common - 2-nitropropane dioxygenase NPD Plav_0824 124 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154251123 Nonpathogen - hypothetical protein Plav_0667 1 None None None 154253589 Common - 6-pyruvoyl tetrahydropterin synthase Plav_3150 81 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 154250861 Nonpathogen - hypothetical protein Plav_0405 3 None None None 154251623 Common - Fmu (Sun) domain protein Plav_1169 205 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 154252377 Common - beta-lactamase domain protein Plav_1929 90 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154251602 Common - regulatory protein LuxR Plav_1148 140 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 154253868 Common - hypothetical protein Plav_3432 12 None None None 154253368 Common - hypothetical protein Plav_2928 10 None None None 154253618 Common - ComEC/Rec2-related protein Plav_3179 145 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 154253293 Common - sugar transporter Plav_2853 68 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154252346 Common - Tetratricopeptide TPR_2 repeat protein Plav_1898 12 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 154253126 Common - histidine triad (HIT) protein Plav_2685 64 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 154251079 Common - lipid A biosynthesis acyltransferase Plav_0623 126 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 154250779 Nonpathogen - hypothetical protein Plav_0323 1 None None None 154251927 Common - Phosphoglycerate mutase Plav_1474 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 154250504 Common - phosphate-selective porin O and P Plav_0048 24 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 154252744 Common - putative transcriptional regulator, GntR family Plav_2297 196 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 154252051 Common - hypothetical protein Plav_1599 28 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 154252745 Common - hypothetical protein Plav_2298 24 COG3813 COG3813, Uncharacterized protein conserved in bacteria Function unknown 154253274 Common - protein of unknown function DUF205 Plav_2834 134 COG0344 COG0344, Predicted membrane protein Function unknown 154252928 Common - Mg2 transporter protein CorA family protein Plav_2486 161 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 154252893 Common - Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase Plav_2451 199 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 154252998 Common - flagellar P-ring protein Plav_2556 104 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 154253861 Common - hypothetical protein Plav_3425 15 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 154250923 Common - protein of unknown function DUF1302 Plav_0467 18 None None None 154253272 Nonpathogen - hypothetical protein Plav_2832 1 None None None 154253697 Common - cysteine desulfurase, SufS subfamily Plav_3259 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 154252779 Nonpathogen - hypothetical protein Plav_2332 1 None None None 154252829 Common - hypothetical protein Plav_2386 24 None None None 154253103 Common - Patatin Plav_2662 129 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 154250772 Nonpathogen - hypothetical protein Plav_0316 1 None None None 154253734 Common - Mammalian cell entry related domain protein Plav_3296 101 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154253032 Nonpathogen - protein of unknown function DUF1457 Plav_2591 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252211 Common - AMP-dependent synthetase and ligase Plav_1759 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251970 Common - metal dependent phosphohydrolase, HD region Plav_1518 16 None None None 154252614 Common - hypothetical protein Plav_2167 17 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154252062 Common - cytochrome B561 Plav_1610 89 COG3038 CybB, Cytochrome B561 Energy production and conversion 154253404 Common - NADH dehydrogenase (quinone) Plav_2964 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 154250965 Common - periplasmic binding protein Plav_0509 20 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154253487 Common - single-strand binding protein Plav_3047 194 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 154253916 Common - ABC transporter related Plav_3484 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 154251525 Common - major facilitator superfamily MFS_1 Plav_1070 93 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154252103 Common - Glutathione S-transferase domain Plav_1651 112 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252252 Common - Carboxymuconolactone decarboxylase Plav_1801 18 COG2128 COG2128, Uncharacterized conserved protein Function unknown 154252441 Common - diacylglycerol kinase catalytic region Plav_1994 121 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 154253117 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Plav_2676 46 COG0546 Gph, Predicted phosphatases General function prediction only 154253101 Common - membrane protein-like protein Plav_2660 23 COG4872 COG4872, Predicted membrane protein Function unknown 154252303 Common - Acireductone dioxygenase ARD Plav_1853 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 154252462 Nonpathogen - response regulator receiver protein Plav_2015 5 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154253477 Common - protein-export membrane protein SecF Plav_3037 210 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 154253093 Common - DSBA oxidoreductase Plav_2652 47 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 154251194 Common - dienelactone hydrolase Plav_0738 10 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 154253198 Common - adenylate kinase Plav_2757 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 154251693 Common - heat shock protein HslVU, ATPase subunit HslU Plav_1240 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 154253072 Nonpathogen - conserved hypothetical protein; putative membrane protein; putative exported protein Plav_2631 5 None None None 154253154 Nonpathogen - hypothetical protein Plav_2713 1 None None None 154253632 Common - ribosome recycling factor Plav_3193 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 154251058 Common - short-chain dehydrogenase/reductase SDR Plav_0602 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154252417 Common - CoA-binding domain protein Plav_1969 198 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 154251446 Common - major facilitator superfamily MFS_1 Plav_0990 81 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 154253755 Common - Methyltransferase type 12 Plav_3318 24 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 154251450 Common - flavin reductase domain protein FMN-binding Plav_0994 47 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 154250602 Nonpathogen - hypothetical protein Plav_0146 1 None None None 154253148 Common - class II aldolase/adducin family protein Plav_2707 104 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 154252139 Common - hypothetical protein Plav_1687 8 None None None 154253635 Common - ribosomal protein S2 Plav_3196 217 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 154250486 Common - HAD-superfamily hydrolase, phosphatase Plav_0030 47 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 154254080 Common - DSBA oxidoreductase Plav_3649 45 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 154253268 Common - NUDIX hydrolase Plav_2828 36 None None None 154250516 Nonpathogen - hypothetical protein Plav_0060 1 None None None 154252784 Common - integrase family protein Plav_2339 74 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 154253285 Nonpathogen - putative histone H1 protein Plav_2845 1 None None None 154253175 Common - translation elongation factor Tu Plav_2734 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 154252805 Common - secretion protein HlyD family protein Plav_2360 124 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154253990 Common - helicase domain protein Plav_3559 229 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 154253503 Common - phosphoadenosine phosphosulfate reductase Plav_3063 138 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 154252501 Common - thioesterase superfamily protein Plav_2054 12 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251108 Common - major facilitator superfamily MFS_1 Plav_0652 111 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 154252534 Nonpathogen - hypothetical protein Plav_2087 1 None None None 154252448 Common - hypothetical protein Plav_2001 11 None None None 154251843 Common - 2'-5' RNA ligase Plav_1390 85 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 154250615 Common - Rieske (2Fe-2S) domain protein Plav_0159 84 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 154252945 Common - major facilitator superfamily MFS_1 Plav_2503 81 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154250843 Nonpathogen - hypothetical protein Plav_0387 5 None None None 154252762 Common - GatB/Yqey domain protein Plav_2315 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 154253132 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Plav_2691 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 154252460 Common - hypothetical protein Plav_2013 7 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154250802 Common - copper-resistance protein, CopA family Plav_0346 128 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 154253095 Nonpathogen - hypothetical protein Plav_2654 9 None None None 154250995 Common - hypothetical protein Plav_0539 12 None None None 154253987 Common - putative transcriptional regulator Plav_3556 49 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 154252130 Common - short-chain dehydrogenase/reductase SDR Plav_1678 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252839 Nonpathogen - protein of unknown function DUF1457 Plav_2397 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154252001 Common - Ornithine carbamoyltransferase Plav_1549 222 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 154252986 Common - hypothetical protein Plav_2544 23 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 154251326 Common - Alpha/beta hydrolase fold-3 domain protein Plav_0870 128 COG0657 Aes, Esterase/lipase Lipid metabolism 154253008 Common - hypothetical protein Plav_2566 13 COG3334 COG3334, Uncharacterized conserved protein Function unknown 154252200 Common - modification methylase, HemK family Plav_1748 208 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 154253929 Common - Tetratricopeptide TPR_2 repeat protein Plav_3497 86 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 154251253 Common - aminotransferase class-III Plav_0797 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 154250670 Common - hypothetical protein Plav_0214 5 None None None 154251296 Common - integral membrane protein-like protein Plav_0840 16 COG5436 COG5436, Predicted integral membrane protein Function unknown 154252368 Nonpathogen - Methyltransferase type 11 Plav_1920 1 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154252884 Nonpathogen - hypothetical protein Plav_2442 1 None None None 154250963 Common - Exo-beta-1 3-glucanase-like protein Plav_0507 14 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 154253222 Common - hypothetical protein Plav_2781 6 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251720 Nonpathogen - hypothetical protein Plav_1267 1 None None None 154252047 Common - cell division ATP-binding protein FtsE Plav_1595 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 154253837 Common - hypothetical protein Plav_3401 13 None None None 154253598 Nonpathogen - hypothetical protein Plav_3159 1 None None None 154253522 Common - DSBA oxidoreductase Plav_3082 78 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 154252195 Common - aspartate kinase Plav_1743 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 154253974 Common - conjugal transfer protein trbB Plav_3543 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 154251346 Common - hypothetical protein Plav_0890 7 None None None 154251933 Common - GTP-binding protein Obg/CgtA Plav_1480 249 COG0536 Obg, Predicted GTPase General function prediction only 154253001 Common - flagellar L-ring protein Plav_2559 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 154252520 Common - sulfate ABC transporter, ATPase subunit Plav_2073 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 154251963 Common - outer membrane autotransporter barrel domain Plav_1511 80 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 154253930 Common - hypothetical protein Plav_3498 12 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 154250733 Common - transcriptional regulator, XRE family Plav_0277 112 COG1396 HipB, Predicted transcriptional regulators Transcription 154252734 Common - hypothetical protein Plav_2287 32 COG4938 COG4938, Uncharacterized conserved protein Function unknown 154253750 Common - hypothetical protein Plav_3313 4 None None None 154253180 Common - ribosomal protein L2 Plav_2739 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 154253676 Common - hypothetical protein Plav_3238 28 COG3671 COG3671, Predicted membrane protein Function unknown 154250796 Common - phage transcriptional regulator, AlpA Plav_0340 5 COG3311 AlpA, Predicted transcriptional regulator Transcription 154251265 Nonpathogen - hypothetical protein Plav_0809 1 None None None 154252860 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Plav_2418 213 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 154250746 Common - peptidase M16 domain protein Plav_0290 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 154251171 Common - efflux transporter, RND family, MFP subunit Plav_0715 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154252283 Common - TRAG family protein Plav_1833 77 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 154251205 Common - glycosyl transferase family 9 Plav_0749 101 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 154253785 Common - NAD-dependent epimerase/dehydratase Plav_3348 81 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154253997 Common - protein of unknown function DUF540 Plav_3566 25 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 154253445 Common - hypothetical protein Plav_3005 25 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 154250766 Common - gamma-glutamyltransferase Plav_0310 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 154253337 Common - Porphobilinogen synthase Plav_2897 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 154252120 Common - sulphate transporter Plav_1668 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 154250649 Common - ABC transporter related Plav_0193 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 154253074 Common - protein of unknown function DUF839 Plav_2633 76 COG3211 PhoX, Predicted phosphatase General function prediction only 154253596 Nonpathogen - preprotein translocase, SecG subunit Plav_3157 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 154251341 Common - transcriptional regulator, TetR family Plav_0885 22 COG1309 AcrR, Transcriptional regulator Transcription 154253162 Common - RNA methyltransferase, TrmH family, group 3 Plav_2721 216 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 154252564 Common - Holliday junction DNA helicase RuvB Plav_2117 224 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 154252398 Common - transcriptional regulator, TetR family Plav_1950 29 COG1309 AcrR, Transcriptional regulator Transcription 154250640 Common - TonB family protein Plav_0184 31 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154250841 Common - heavy metal translocating P-type ATPase Plav_0385 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154250676 Common - phenylalanyl-tRNA synthetase, alpha subunit Plav_0220 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 154251279 Common - NAD-dependent epimerase/dehydratase Plav_0823 45 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154252156 Common - hypothetical protein Plav_1704 15 None None None 154250643 Common - Superoxide dismutase Plav_0187 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 154253965 Common - hypothetical protein Plav_3534 23 None None None 154253769 Common - phosphoribosylglycinamide formyltransferase Plav_3332 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 154253261 Common - transcriptional regulator, TetR family Plav_2820 2 COG1309 AcrR, Transcriptional regulator Transcription 154251272 Common - asparagine synthase (glutamine-hydrolyzing) Plav_0816 156 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 154253229 Common - Carbamoyl-phosphate synthase L chain ATP-binding Plav_2788 227 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 154251339 Common - MscS Mechanosensitive ion channel Plav_0883 126 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154252027 Common - protein of unknown function DUF882 Plav_1575 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 154250975 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Plav_0519 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 154253765 Common - Chromosomal replication initiator DnaA Plav_3328 86 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 154253422 Common - biotin/lipoyl attachment domain-containing protein Plav_2982 89 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 154251001 Common - 4-alpha-glucanotransferase Plav_0545 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 154251678 Common - Domain of unknown function DUF1814 Plav_1225 30 COG2253 COG2253, Uncharacterized conserved protein Function unknown 154251371 Common - phage-related minor tail protein-like protein Plav_0915 14 COG5281 COG5281, Phage-related minor tail protein Function unknown 154251727 Common - glucose inhibited division protein A Plav_1274 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 154252653 Common - AMP-dependent synthetase and ligase Plav_2206 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154250930 Common - Enoyl-CoA hydratase/isomerase Plav_0474 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154250700 Common - NLP/P60 protein Plav_0244 106 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 154251189 Common - L-aspartate oxidase Plav_0733 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 154250630 Common - Protein of unknown function DUF1974 Plav_0174 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252098 Common - luciferase family protein Plav_1646 131 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154251330 Nonpathogen - transcriptional regulator, XRE family Plav_0874 5 COG1396 HipB, Predicted transcriptional regulators Transcription 154253839 Common - hypothetical protein Plav_3403 11 None None None 154253884 Common - Phosphate butyryltransferase Plav_3451 150 COG0280 Pta, Phosphotransacetylase Energy production and conversion 154251167 Common - plasmid stabilization system Plav_0711 30 COG3668 ParE, Plasmid stabilization system protein General function prediction only 154252042 Common - diacylglycerol kinase catalytic region Plav_1590 99 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 154250729 Common - short-chain dehydrogenase/reductase SDR Plav_0273 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251141 Common - homoserine kinase Plav_0685 66 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 154251151 Common - H+transporting two-sector ATPase B/B' subunit Plav_0695 40 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 154254091 Nonpathogen - hypothetical protein Plav_3660 3 None None None 154250838 Nonpathogen - hypothetical protein Plav_0382 1 None None None 154251582 Common - hypothetical protein Plav_1128 21 COG5470 COG5470, Uncharacterized conserved protein Function unknown 154253796 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Plav_3359 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154250973 Common - helix-turn-helix- domain containing protein AraC type Plav_0517 131 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154251883 Common - MaoC domain protein dehydratase Plav_1430 63 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154253461 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Plav_3021 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 154253511 Common - membrane bound O-acyl transferase MBOAT family protein Plav_3071 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 154251916 Common - ATP synthase F1, alpha subunit Plav_1463 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 154252247 Common - D-aminoacylase domain protein Plav_1796 63 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 154251788 Common - GCN5-related N-acetyltransferase Plav_1335 19 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 154251822 Common - glutamine amidotransferase class-I Plav_1369 145 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 154252037 Nonpathogen - hypothetical protein Plav_1585 10 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 154250652 Common - 3'-5' exonuclease Plav_0196 103 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 154250919 Common - acyl-CoA dehydrogenase domain protein Plav_0463 155 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253830 Common - hypothetical protein Plav_3394 12 None None None 154252760 Common - carbamoyl-phosphate synthase, large subunit Plav_2313 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 154251604 Common - Acetone carboxylase gamma subunit Plav_1150 21 COG4647 AcxC, Acetone carboxylase, gamma subunit Secondary metabolites biosynthesis, transport, and catabolism 154253206 Common - AAA ATPase central domain protein Plav_2765 224 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 154253934 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_3502 45 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 154254057 Common - NusA antitermination factor Plav_3626 219 COG0195 NusA, Transcription elongation factor Transcription 154250819 Common - 2-nitropropane dioxygenase NPD Plav_0363 142 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154251803 Common - Uroporphyrinogen III synthase HEM4 Plav_1350 42 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 154253388 Common - single-stranded-DNA-specific exonuclease RecJ Plav_2948 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 154253429 Common - Rhodanese domain protein Plav_2989 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 154254067 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA Plav_3636 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 154252008 Common - NUDIX hydrolase Plav_1556 63 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 154254050 Common - protein of unknown function UPF0054 Plav_3619 141 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 154252331 Common - TonB-dependent receptor Plav_1883 93 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154251736 Common - sulfotransferase Plav_1283 19 None None None 154252875 Common - protein involved in cellulose biosynthesis (CelD)-like protein Plav_2433 8 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 154253856 Common - hypothetical protein Plav_3420 19 COG2183 Tex, Transcriptional accessory protein Transcription 154253330 Common - MotA/TolQ/ExbB proton channel Plav_2890 152 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154253518 Common - protein of unknown function DUF502 Plav_3078 83 COG2928 COG2928, Uncharacterized conserved protein Function unknown 154252867 Common - Polypeptide-transport-associated domain protein FtsQ-type Plav_2425 87 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 154252593 Common - inner membrane protein Plav_2146 22 COG3686 COG3686, Predicted membrane protein Function unknown 154253356 Common - V-type H(+)-translocating pyrophosphatase Plav_2916 99 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 154251775 Common - Ribulose-phosphate 3-epimerase Plav_1322 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 154250955 Common - acyl-CoA dehydrogenase domain protein Plav_0499 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154250460 Common - DNA polymerase III, beta subunit Plav_0004 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 154252724 Common - dihydroneopterin aldolase Plav_2277 79 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 154250561 Common - DNA polymerase I Plav_0105 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 154251732 Nonpathogen - hypothetical protein Plav_1279 6 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 154250668 Common - Phytanoyl-CoA dioxygenase Plav_0212 20 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 154250727 Common - DinB family protein Plav_0271 33 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 154250893 Common - dihydroorotate dehydrogenase Plav_0437 235 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 154251751 Common - peptidase C26 Plav_1298 112 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 154251993 Common - monooxygenase FAD-binding Plav_1541 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 154253971 Common - hypothetical protein Plav_3540 23 None None None 154250910 Common - putative ICC-like phosphoesterase Plav_0454 52 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 154252675 Common - ABC-3 protein Plav_2228 118 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 154251014 Common - AMP-dependent synthetase and ligase Plav_0558 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253430 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Plav_2990 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 154253904 Nonpathogen - protein of unknown function DUF433 Plav_3472 8 COG2442 COG2442, Uncharacterized conserved protein Function unknown 154251952 Common - Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ Plav_1500 24 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 154253056 Common - alpha/beta hydrolase fold Plav_2615 170 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252858 Common - UDP-N-acetylmuramyl-tripeptide synthetase Plav_2416 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 154251161 Common - transcriptional regulator, MarR family Plav_0705 117 COG1846 MarR, Transcriptional regulators Transcription 154253139 Common - beta-ketoadipyl CoA thiolase Plav_2698 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253084 Common - type IV pilus assembly PilZ Plav_2643 12 None None None 154253376 Common - thioesterase superfamily protein Plav_2936 35 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154253760 Common - hypothetical protein Plav_3323 19 COG2510 COG2510, Predicted membrane protein Function unknown 154252325 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1877 196 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 154251490 Common - glucose-methanol-choline oxidoreductase Plav_1035 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 154252933 Common - acyltransferase 3 Plav_2491 109 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 154252338 Common - hypothetical protein Plav_1890 48 COG3665 COG3665, Uncharacterized conserved protein Function unknown 154251829 Common - Inorganic diphosphatase Plav_1376 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 154253291 Common - transcriptional regulator, TetR family Plav_2851 11 COG1309 AcrR, Transcriptional regulator Transcription 154250530 Common - type II secretion system protein Plav_0074 73 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 154250539 Common - metal-dependent hydrolase-like protein Plav_0083 25 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 154253608 Common - anthranilate synthase component I Plav_3169 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 154250511 Common - CsbD family protein Plav_0055 54 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 154250937 Common - Enoyl-CoA hydratase/isomerase Plav_0481 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252715 Common - integral membrane sensor signal transduction histidine kinase Plav_2268 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154251537 Common - alpha/beta hydrolase fold Plav_1082 89 COG2267 PldB, Lysophospholipase Lipid metabolism 154252751 Common - sulfotransferase Plav_2304 15 None None None 154252865 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Plav_2423 188 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 154252348 Common - putative ribonuclease BN Plav_1900 114 COG1295 Rbn, Predicted membrane protein Function unknown 154252576 Common - transcriptional regulator, TetR family Plav_2129 5 COG1309 AcrR, Transcriptional regulator Transcription 154251668 Common - putative plasmid stability protein StbC Plav_1215 26 COG4691 StbC, Plasmid stability protein General function prediction only 154251125 Common - Cytochrome c oxidase subunit II Plav_0669 154 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 154252379 Nonpathogen - hypothetical protein Plav_1931 1 None None None 154251127 Common - protoheme IX farnesyltransferase Plav_0671 176 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 154251850 Common - ABC transporter related Plav_1397 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154253190 Common - ribosomal protein S14 Plav_2749 206 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 154253790 Common - glucose-1-phosphate cytidylyltransferase Plav_3353 147 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 154253773 Common - DNA polymerase III chi subunit HolC Plav_3336 53 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 154251231 Common - acyl-CoA dehydrogenase domain protein Plav_0775 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251702 Common - FxsA cytoplasmic membrane protein Plav_1249 70 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 154251405 Common - glycine cleavage T protein (aminomethyl transferase) Plav_0949 177 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 154252119 Common - AMP-dependent synthetase and ligase Plav_1667 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252370 Common - NAD-dependent epimerase/dehydratase Plav_1922 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154253682 Common - glutamine synthetase, type I Plav_3244 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154253247 Common - protein of unknown function DUF323 Plav_2806 102 COG1262 COG1262, Uncharacterized conserved protein Function unknown 154250707 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Plav_0251 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 154252844 Common - homocysteine S-methyltransferase Plav_2402 162 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 154253538 Common - HpcH/HpaI aldolase Plav_3098 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 154251901 Common - AFG1-family ATPase Plav_1448 101 COG1485 COG1485, Predicted ATPase General function prediction only 154251170 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Plav_0714 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154253582 Common - Septum formation initiator Plav_3142 28 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 154251071 Common - oxidoreductase domain protein Plav_0615 76 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 154252716 Common - two component transcriptional regulator, winged helix family Plav_2269 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154251929 Common - iojap-like protein Plav_1476 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 154253378 Common - ribosomal protein S9 Plav_2938 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 154250929 Common - hypothetical protein Plav_0473 9 None None None 154251024 Nonpathogen - hypothetical protein Plav_0568 1 None None None 154252243 Common - 3-oxosteroid 1-dehydrogenase Plav_1792 59 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154250603 Common - integration host factor, beta subunit Plav_0147 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 154250773 Nonpathogen - hypothetical protein Plav_0317 9 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 154252147 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Plav_1695 161 COG1146 COG1146, Ferredoxin Energy production and conversion 154252742 Common - Vault protein inter-alpha-trypsin domain protein Plav_2295 47 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 154252993 Common - putative flagellin protein, C-terminus Plav_2551 79 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 154252110 Common - Carboxymuconolactone decarboxylase Plav_1658 32 COG2128 COG2128, Uncharacterized conserved protein Function unknown 154253355 Common - thiamine-monophosphate kinase Plav_2915 195 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 154252168 Common - protein of unknown function DUF21 Plav_1716 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 154251067 Common - chaperonin Cpn10 Plav_0611 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 154252822 Common - integral membrane sensor signal transduction histidine kinase Plav_2379 219 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154252824 Common - response regulator receiver protein Plav_2381 201 COG4566 TtrR, Response regulator Signal transduction mechanisms 154253480 Common - putative phytoene synthase Plav_3040 49 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 154252660 Nonpathogen - hypothetical protein Plav_2213 3 None None None 154252064 Nonpathogen - Hypoxia induced protein conserved region Plav_1612 4 None None None 154253978 Common - P-type conjugative transfer protein TrbL Plav_3547 31 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 154253820 Common - hypothetical protein Plav_3383 15 None None None 154250505 Common - OsmC family protein Plav_0049 59 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 154252320 Common - diguanylate cyclase/phosphodiesterase Plav_1871 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 154251746 Common - transcriptional regulator, TetR family Plav_1293 61 COG1309 AcrR, Transcriptional regulator Transcription 154251779 Common - sun protein Plav_1326 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 154251455 Common - transcriptional regulator, LysR family Plav_0999 176 COG0583 LysR, Transcriptional regulator Transcription 154253611 Common - anthranilate phosphoribosyltransferase Plav_3172 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 154253743 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Plav_3305 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 154253323 Common - Arginyltransferase Plav_2883 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 154251605 Common - 5-oxoprolinase (ATP-hydrolyzing) Plav_1151 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252359 Nonpathogen - hypothetical protein Plav_1911 1 None None None 154251626 Common - integrase family protein Plav_1172 110 COG0582 XerC, Integrase DNA replication, recombination, and repair 154251911 Common - protein of unknown function DUF484 Plav_1458 17 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 154254056 Common - protein of unknown function DUF150 Plav_3625 169 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 154253063 Nonpathogen - hypothetical protein Plav_2622 1 None None None 154252511 Common - TonB-dependent siderophore receptor Plav_2064 91 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154251830 Common - Argininosuccinate synthase Plav_1377 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 154253399 Common - ATPase associated with various cellular activities AAA_5 Plav_2959 102 COG0714 COG0714, MoxR-like ATPases General function prediction only 154253123 Common - Citrate (pro-3S)-lyase Plav_2682 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 154253562 Common - inositol monophosphatase Plav_3122 183 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 154250712 Common - hypothetical protein Plav_0256 167 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 154252941 Common - protein of unknown function DUF423 Plav_2499 64 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 154251225 Common - protein of unknown function DUF21 Plav_0769 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 154253691 Common - aldehyde dehydrogenase Plav_3253 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154251091 Common - hypothetical protein Plav_0635 19 COG4683 COG4683, Uncharacterized protein conserved in bacteria Function unknown 154250987 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Plav_0531 184 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154254078 Common - hypothetical protein Plav_3647 15 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 154251686 Common - imidazoleglycerol phosphate synthase, cyclase subunit Plav_1233 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 154252736 Nonpathogen - hypothetical protein Plav_2289 1 None None None 154251579 Nonpathogen - transcriptional regulator, TetR family Plav_1125 4 COG1309 AcrR, Transcriptional regulator Transcription 154253390 Nonpathogen - hypothetical protein Plav_2950 4 None None None 154252459 Common - nitroreductase Plav_2012 78 COG0778 NfnB, Nitroreductase Energy production and conversion 154252953 Common - cytochrome c class I Plav_2511 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 154250920 Common - acetyl-CoA acetyltransferase Plav_0464 177 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154251327 Common - transcriptional regulator, MucR family Plav_0871 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 154252924 Common - Peptidoglycan glycosyltransferase Plav_2482 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 154251352 Common - ABC transporter related Plav_0896 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 154251846 Common - ABC transporter related Plav_1393 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 154253415 Common - thioesterase superfamily protein Plav_2975 28 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154252445 Common - response regulator receiver protein Plav_1998 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154251130 Common - protein of unknown function DUF983 Plav_0674 29 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 154253554 Common - hydrolase, TatD family Plav_3114 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 154253909 Common - putative nitrogen regulatory protein P-II family protein Plav_3477 22 None None None 154253666 Common - major facilitator superfamily MFS_1 Plav_3228 78 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251820 Common - Acyl-CoA dehydrogenase type 2 domain Plav_1367 69 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252131 Common - acyl-CoA dehydrogenase domain protein Plav_1679 139 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154250822 Common - FAD dependent oxidoreductase Plav_0366 73 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154253019 Common - fatty acid desaturase Plav_2577 34 COG3239 DesA, Fatty acid desaturase Lipid metabolism 154251709 Common - protein of unknown function DUF299 Plav_1256 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 154253402 Common - (2Fe-2S)-binding domain protein Plav_2962 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 154250521 Common - response regulator receiver protein Plav_0065 162 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154252536 Common - short-chain dehydrogenase/reductase SDR Plav_2089 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252649 Common - high-affinity nickel-transporter Plav_2202 42 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 154250462 Common - Endopeptidase Clp Plav_0006 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154250535 Common - histidine kinase Plav_0079 212 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154251638 Common - hypothetical protein Plav_1184 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 154253000 Common - transcriptional regulator, TraR/DksA family Plav_2558 118 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 154252948 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_2506 48 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 154250572 Common - hypothetical protein Plav_0116 13 None None None 154251940 Common - phospholipid/glycerol acyltransferase Plav_1487 60 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 154253197 Common - preprotein translocase, SecY subunit Plav_2756 217 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 154252879 Common - Chloride channel core Plav_2437 155 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 154253651 Common - biotin--acetyl-CoA-carboxylase ligase Plav_3212 225 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 154251503 Common - SMC domain protein Plav_1048 55 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154251396 Common - CcmE/CycJ protein Plav_0940 93 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 154253257 Common - ribosomal protein L33 Plav_2816 126 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 154252233 Common - cytochrome P450 Plav_1782 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154251516 Common - acyl-CoA dehydrogenase domain protein Plav_1061 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251354 Common - protein of unknown function UPF0153 Plav_0898 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 154251769 Common - major facilitator superfamily MFS_1 Plav_1316 61 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 154252012 Common - hypothetical protein Plav_1560 14 None None None 154252546 Common - hypothetical protein Plav_2099 28 None None None 154250901 Common - Alpha/beta hydrolase fold-3 domain protein Plav_0445 122 COG0657 Aes, Esterase/lipase Lipid metabolism 154253163 Common - translation elongation factor Tu Plav_2722 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 154253720 Common - fatty acid desaturase Plav_3282 36 COG3239 DesA, Fatty acid desaturase Lipid metabolism 154251460 Common - putative nitric-oxide reductase Plav_1004 72 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 154253953 Common - PilT protein domain protein Plav_3521 52 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 154253966 Common - conjugal transfer protein precursor Plav_3535 28 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154254006 Common - Sel1 domain protein repeat-containing protein Plav_3575 4 None None None 154251097 Common - riboflavin biosynthesis protein RibF Plav_0641 211 COG0196 RibF, FAD synthase Coenzyme metabolism 154253221 Common - acyl-CoA dehydrogenase domain protein Plav_2780 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251648 Common - P-type conjugative transfer ATPase TrbB Plav_1194 144 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 154250626 Common - acriflavin resistance protein Plav_0170 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154251090 Common - Class I peptide chain release factor Plav_0634 113 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 154252192 Common - FAD-linked oxidoreductase Plav_1740 46 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 154252391 Common - 20S proteasome A and B subunits Plav_1943 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 154251254 Common - Amidase Plav_0798 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154252817 Common - isochorismatase hydrolase Plav_2374 81 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 154253847 Common - conserved hypothetical protein; putative signal peptide Plav_3411 21 None None None 154252452 Common - Glutathione S-transferase domain Plav_2005 102 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253386 Common - Homoserine dehydrogenase Plav_2946 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 154251193 Common - hypothetical protein Plav_0737 16 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 154253205 Nonpathogen - hypothetical protein Plav_2764 4 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 154253105 Common - GTP cyclohydrolase I Plav_2664 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 154253336 Common - transcriptional regulator, TetR family Plav_2896 62 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 154251832 Common - antibiotic biosynthesis monooxygenase Plav_1379 8 None None None 154253208 Common - pseudouridine synthase, RluA family Plav_2767 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 154251271 Common - Glutathione synthase Plav_0815 61 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 154253471 Common - stationary-phase survival protein SurE Plav_3031 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 154252615 Common - hypothetical protein Plav_2168 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 154251044 Common - transcriptional regulator, XRE family Plav_0588 31 COG1396 HipB, Predicted transcriptional regulators Transcription 154251030 Nonpathogen - hypothetical protein Plav_0574 2 None None None 154251646 Common - conjugal transfer protein trbB Plav_1192 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 154252885 Common - AsmA family protein Plav_2443 42 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 154250903 Common - protein of unknown function UPF0016 Plav_0447 63 COG2119 COG2119, Predicted membrane protein Function unknown 154252555 Common - transketolase Plav_2108 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 154250868 Common - LrgB family protein Plav_0412 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 154251994 Common - putative monooxygenase Plav_1542 60 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154251297 Common - protein of unknown function DUF1214 Plav_0841 34 COG5402 COG5402, Uncharacterized conserved protein Function unknown 154252895 Common - amine oxidase Plav_2453 25 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 154252964 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Plav_2522 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 154253043 Common - hypothetical protein Plav_2602 35 None None None 154253363 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Plav_2923 214 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 154251150 Common - H+transporting two-sector ATPase B/B' subunit Plav_0694 33 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 154252221 Common - short-chain dehydrogenase/reductase SDR Plav_1769 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253783 Common - Cephalosporin hydroxylase Plav_3346 20 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 154252580 Common - putative transcriptional regulator, GntR family Plav_2133 121 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 154252773 Common - two component transcriptional regulator, LuxR family Plav_2326 170 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154250851 Common - phosphate ABC transporter, inner membrane subunit PstC Plav_0395 234 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 154250544 Nonpathogen - transcriptional regulator, TetR family Plav_0088 5 COG1309 AcrR, Transcriptional regulator Transcription 154251469 Common - K+-transporting ATPase, B subunit Plav_1013 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 154250479 Common - hypothetical protein Plav_0023 11 None None None 154250784 Common - hypothetical protein Plav_0328 5 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 154253500 Common - SH3 type 3 domain protein Plav_3060 59 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 154254071 Common - hypothetical protein Plav_3640 13 None None None 154251597 Common - amino acid permease-associated region Plav_1143 164 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 154252632 Common - protein of unknown function DUF1153 Plav_2185 27 None None None 154253813 Common - phage transcriptional regulator, AlpA Plav_3376 35 COG3311 AlpA, Predicted transcriptional regulator Transcription 154253866 Common - hypothetical protein Plav_3430 11 None None None 154252704 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Plav_2257 191 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 154250470 Common - Classical-complement-pathway C3/C5 convertase Plav_0014 107 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 154251290 Common - regulatory protein IclR Plav_0834 54 COG1414 IclR, Transcriptional regulator Transcription 154252589 Common - OsmC family protein Plav_2142 24 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 154253434 Common - polysaccharide deacetylase Plav_2994 39 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 154253235 Common - Glutamate--ammonia ligase Plav_2794 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154252250 Common - NADH:flavin oxidoreductase/NADH oxidase Plav_1799 195 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 154253036 Common - PilT protein domain protein Plav_2595 17 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 154250681 Common - TadE family protein Plav_0225 15 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 154252872 Common - DNA uptake lipoprotein Plav_2430 127 COG4105 ComL, DNA uptake lipoprotein General function prediction only 154253574 Common - CinA domain protein Plav_3134 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 154250814 Common - signal transduction histidine kinase Plav_0358 137 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 154251159 Common - Ribonuclease H Plav_0703 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 154252261 Common - hypothetical protein Plav_1811 13 None None None 154253718 Common - peptidase M48 Ste24p Plav_3280 115 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 154253391 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_2951 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154252392 Nonpathogen - hypothetical protein Plav_1944 1 None None None 154251422 Common - Glutathione S-transferase domain Plav_0966 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253478 Common - protein of unknown function DUF498 Plav_3038 45 COG3737 COG3737, Uncharacterized conserved protein Function unknown 154253572 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Plav_3132 196 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 154252184 Common - arginine biosynthesis bifunctional protein ArgJ Plav_1732 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 154253492 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Plav_3052 190 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 154254012 Common - Ham1 family protein Plav_3581 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 154250787 Nonpathogen - hypothetical protein Plav_0331 2 None None None 154252912 Common - cation diffusion facilitator family transporter Plav_2470 215 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 154253795 Common - acyl carrier protein Plav_3358 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154252381 Common - galactose-1-phosphate uridylyltransferase Plav_1933 67 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 154252277 Nonpathogen - hypothetical protein Plav_1827 5 None None None 154252540 Nonpathogen - protein of unknown function DUF1192 Plav_2093 5 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 154250943 Nonpathogen - hypothetical protein Plav_0487 1 None None None 154253880 Common - ABC-2 type transporter Plav_3447 136 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 154253547 Common - MmgE/PrpD family protein Plav_3107 57 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 154251892 Common - Antibiotic biosynthesis monooxygenase Plav_1439 20 COG1359 COG1359, Uncharacterized conserved protein Function unknown 154251435 Common - Alkaline phosphatase Plav_0979 55 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 154252429 Common - histidinol-phosphate phosphatase, putative Plav_1982 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 154250488 Common - Cobyrinic acid ac-diamide synthase Plav_0032 84 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154251137 Common - protein of unknown function DUF179 Plav_0681 130 COG1678 COG1678, Putative transcriptional regulator Transcription 154251556 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_1102 112 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 154254020 Common - glutathione synthetase Plav_3589 142 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 154250597 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Plav_0141 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 154252021 Common - gamma-glutamyltransferase Plav_1569 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 154251815 Common - Excinuclease ABC C subunit domain protein Plav_1362 57 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 154250568 Common - integral membrane sensor signal transduction histidine kinase Plav_0112 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253307 Common - DNA-directed RNA polymerase, omega subunit Plav_2867 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 154252927 Common - DEAD/DEAH box helicase domain protein Plav_2485 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 154252087 Common - Disulphide bond formation protein DsbB Plav_1635 31 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 154251085 Common - hypothetical protein Plav_0629 24 None None None 154250529 Common - type II secretion system protein Plav_0073 65 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 154251174 Common - phage SPO1 DNA polymerase-related protein Plav_0718 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 154251972 Common - HI0933 family protein Plav_1520 84 COG2081 COG2081, Predicted flavoproteins General function prediction only 154253706 Common - hypothetical protein Plav_3268 11 None None None 154252318 Common - amine oxidase Plav_1869 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 154250761 Common - integral membrane sensor signal transduction histidine kinase Plav_0305 205 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154252670 Common - transcriptional regulator, LysR family Plav_2223 170 COG0583 LysR, Transcriptional regulator Transcription 154251714 Nonpathogen - protein of unknown function DUF1457 Plav_1261 1 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154253805 Common - insertion element protein Plav_3368 8 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 154253137 Common - DoxX family protein Plav_2696 17 COG2259 COG2259, Predicted membrane protein Function unknown 154253362 Common - fatty acid/phospholipid synthesis protein PlsX Plav_2922 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 154251363 Nonpathogen - hypothetical protein Plav_0907 4 None None None 154252677 Common - protein of unknown function UPF0060 Plav_2230 46 COG1742 COG1742, Uncharacterized conserved protein Function unknown 154250953 Common - hypothetical protein Plav_0497 26 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 154251243 Common - chaperone DnaJ domain protein Plav_0787 228 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154251473 Common - Enoyl-CoA hydratase/isomerase Plav_1018 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253237 Common - Serine-type D-Ala-D-Ala carboxypeptidase Plav_2796 147 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 154252333 Common - Rhomboid family protein Plav_1885 155 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 154254042 Common - Scaffold protein Nfu/NifU Plav_3611 105 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 154253306 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Plav_2866 193 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 154250540 Common - helix-turn-helix- domain containing protein AraC type Plav_0084 74 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154252361 Common - glycosyl transferase group 1 Plav_1913 94 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154251310 Common - major facilitator superfamily MFS_1 Plav_0854 89 None None None 154250683 Common - von Willebrand factor type A Plav_0227 21 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 154252590 Common - Pirin domain protein Plav_2143 142 COG1741 COG1741, Pirin-related protein General function prediction only 154252939 Common - alpha/beta hydrolase fold Plav_2497 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252599 Common - Amidohydrolase 3 Plav_2152 77 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 154252475 Common - TPR repeat-containing protein Plav_2028 29 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 154251589 Common - FAD dependent oxidoreductase Plav_1135 23 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 154252339 Common - hypothetical protein Plav_1891 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 154254004 Common - chaperone protein DnaJ Plav_3573 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154253762 Common - Ppx/GppA phosphatase Plav_3325 173 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 154251119 Common - DinB family protein Plav_0663 15 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 154253832 Common - hypothetical protein Plav_3396 8 None None None 154251827 Common - conserved hypothetical protein; K09982 hypothetical protein Plav_1374 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 154252726 Common - Na+/Ca+ antiporter, CaCA family Plav_2279 125 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 154251776 Common - methyltransferase FkbM family Plav_1323 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252930 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Plav_2488 185 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 154253672 Common - Orn/DAP/Arg decarboxylase 2 Plav_3234 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 154253876 Common - hypothetical protein Plav_3442 16 None None None 154250660 Common - alpha/beta hydrolase fold Plav_0204 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253914 Common - alanine racemase Plav_3482 196 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 154251427 Common - hypothetical protein Plav_0971 16 None None None 154253048 Common - methylase Plav_2607 43 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 154250932 Common - thioesterase-like protein Plav_0476 22 COG0824 FcbC, Predicted thioesterase General function prediction only 154253857 Common - putative secreted protein Plav_3421 21 None None None 154253564 Common - RNA chaperone Hfq Plav_3124 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 154251996 Common - cytochrome P450 Plav_1544 85 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154253517 Common - hypothetical protein Plav_3077 5 None None None 154250977 Common - Histidinol dehydrogenase Plav_0521 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 154253130 Common - transcriptional regulator, BadM/Rrf2 family Plav_2689 86 COG1959 COG1959, Predicted transcriptional regulator Transcription 154250720 Common - glutamate racemase Plav_0264 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 154252480 Common - protein of unknown function DUF1244 Plav_2033 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 154253793 Common - aminodeoxychorismate lyase Plav_3356 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 154254022 Common - Membrane dipeptidase Plav_3591 96 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 154253467 Common - twin-arginine translocation protein, TatA/E family subunit Plav_3027 21 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 154252698 Common - transcriptional regulator, MarR family Plav_2251 131 COG1846 MarR, Transcriptional regulators Transcription 154253223 Common - phosphoesterase PA-phosphatase related Plav_2782 42 None None None 154251498 Common - hypothetical protein Plav_1043 20 None None None 154251695 Common - 2OG-Fe(II) oxygenase Plav_1242 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 154250654 Common - putative transcriptional regulator, MerR family Plav_0198 140 COG0789 SoxR, Predicted transcriptional regulators Transcription 154251675 Common - ParB domain protein nuclease Plav_1222 158 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154252651 Common - acyl-CoA dehydrogenase domain protein Plav_2204 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251758 Common - ammonium transporter Plav_1305 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 154251442 Common - Taurine dioxygenase Plav_0986 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154251670 Common - hypothetical protein Plav_1217 37 None None None 154251383 Nonpathogen - Propeptide PepSY amd peptidase M4 Plav_0927 2 COG3212 COG3212, Predicted membrane protein Function unknown 154254061 Common - tRNA pseudouridine synthase B Plav_3630 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 154252436 Common - major facilitator superfamily MFS_1 Plav_1989 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251535 Common - Abortive infection protein Plav_1080 3 None None None 154252604 Nonpathogen - hypothetical protein Plav_2157 2 None None None 154251007 Common - Cupin 2 conserved barrel domain protein Plav_0551 33 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 154251612 Nonpathogen - hypothetical protein Plav_1158 2 None None None 154250837 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_0381 122 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 154252617 Nonpathogen - hypothetical protein Plav_2170 3 None None None 154252629 Nonpathogen - putative flagellar assembly protein FliH Plav_2182 9 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 154253432 Common - Cyclopropane-fatty-acyl-phospholipid synthase Plav_2992 129 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 154252123 Common - FAD dependent oxidoreductase Plav_1671 153 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 154250709 Nonpathogen - hypothetical protein Plav_0253 1 None None None 154252096 Common - SirA family protein Plav_1644 95 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 154252835 Common - ABC transporter related Plav_2392 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 154253985 Common - hypothetical protein Plav_3554 5 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 154252025 Common - acetyl-CoA acetyltransferase Plav_1573 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154252407 Common - membrane bound O-acyl transferase MBOAT family protein Plav_1959 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 154252567 Common - Biopolymer transport TolR Plav_2120 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154250911 Common - cytochrome c biogenesis protein transmembrane region Plav_0455 104 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 154253423 Common - cystathionine beta-lyase Plav_2983 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 154250564 Common - Helix-turn-helix type 11 domain protein Plav_0108 98 COG2378 COG2378, Predicted transcriptional regulator Transcription 154250593 Common - Double-strand break repair protein AddB Plav_0137 56 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 154252754 Common - TPR repeat-containing protein Plav_2307 26 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 154251772 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Plav_1319 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 154253748 Common - transferase hexapeptide repeat containing protein Plav_3311 109 COG1043 LpxA, Acyl- acyl carrier protein 154251624 Common - hypothetical protein Plav_1170 8 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 154253321 Common - Tripartite ATP-independent periplasmic transporter DctQ component Plav_2881 71 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 154251256 Common - hypothetical protein Plav_0800 28 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 154250725 Common - peptidase U34 dipeptidase Plav_0269 8 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 154250639 Common - Haemin-degrading family protein Plav_0183 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 154253920 Common - short-chain dehydrogenase/reductase SDR Plav_3488 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154252575 Common - cytochrome P450 Plav_2128 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154252075 Common - Cyclohexanone monooxygenase Plav_1623 49 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154251566 Common - Peptidoglycan-binding LysM Plav_1112 40 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 154250848 Common - acyl-CoA dehydrogenase domain protein Plav_0392 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252605 Common - protein of unknown function UPF0118 Plav_2158 160 COG0628 PerM, Predicted permease General function prediction only 154252494 Nonpathogen - hypothetical protein Plav_2047 8 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 154250800 Common - 2-oxo-hepta-3-ene-1,7-dioic acid hydratase Plav_0344 58 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 154250966 Common - transport system permease protein Plav_0510 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154253906 Common - DoxX family protein Plav_3474 57 COG2259 COG2259, Predicted membrane protein Function unknown 154253182 Common - ribosomal protein L22 Plav_2741 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 154250775 Common - hypothetical protein Plav_0319 12 None None None 154252154 Common - methylmalonyl-CoA mutase, large subunit Plav_1702 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 154250993 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Plav_0537 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 154252995 Common - Tetratricopeptide TPR_2 repeat protein Plav_2553 84 COG0457 NrfG, FOG: TPR repeat General function prediction only 154250647 Common - sigma 54 modulation protein/ribosomal protein S30EA Plav_0191 52 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 154250679 Common - GTP-binding protein LepA Plav_0223 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 154252946 Common - Taurine dioxygenase Plav_2504 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154253166 Common - ribosomal protein L11 Plav_2725 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 154250790 Nonpathogen - hypothetical protein Plav_0334 1 None None None 154250739 Common - putative methylisocitrate lyase Plav_0283 122 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 154252327 Nonpathogen - hypothetical protein Plav_1879 4 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 154252443 Common - Lytic transglycosylase catalytic Plav_1996 45 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154253438 Nonpathogen - transcription factor jumonji/aspartyl beta-hydroxylase Plav_2998 7 None None None 154250755 Common - 60 kDa inner membrane insertion protein Plav_0299 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 154252149 Common - RNA-binding S4 domain protein Plav_1697 109 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 154252108 Common - hypothetical protein Plav_1656 6 None None None 154250662 Nonpathogen - hypothetical protein Plav_0206 1 None None None 154253642 Common - ABC transporter related Plav_3203 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154250768 Common - filamentation induced by cAMP protein Fic Plav_0312 34 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 154253822 Common - DNA topoisomerase III Plav_3385 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 154252547 Nonpathogen - hypothetical protein Plav_2100 1 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154251301 Common - methionine-R-sulfoxide reductase Plav_0845 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 154252049 Common - hypoxanthine phosphoribosyltransferase Plav_1597 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 154250672 Nonpathogen - hypothetical protein Plav_0216 3 None None None 154251202 Common - protein of unknown function DUF583 Plav_0746 52 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 154252554 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Plav_2107 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 154253911 Common - protein of unknown function DUF1538 Plav_3479 23 None None None 154251804 Common - hypothetical protein Plav_1351 6 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 154251347 Common - binding-protein-dependent transport systems inner membrane component Plav_0891 179 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 154250587 Common - 2,4-dichlorophenol 6-monooxygenase Plav_0131 115 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 154252275 Common - hypothetical protein Plav_1825 23 None None None 154251798 Nonpathogen - hypothetical protein Plav_1345 1 None None None 154253591 Common - integral membrane sensor signal transduction histidine kinase Plav_3152 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253121 Common - Amidohydrolase 3 Plav_2680 54 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 154253354 Common - NusB antitermination factor Plav_2914 175 COG0781 NusB, Transcription termination factor Transcription 154252410 Common - AzlC family protein Plav_1962 102 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 154251278 Common - transcriptional regulator, LysR family Plav_0822 178 COG0583 LysR, Transcriptional regulator Transcription 154253528 Common - L-carnitine dehydratase/bile acid-inducible protein F Plav_3088 113 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 154253892 Common - D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Plav_3459 64 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 154252808 Common - alpha/beta hydrolase fold Plav_2363 102 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154250457 Common - ribosomal protein S20 Plav_0001 193 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 154252263 Common - helix-turn-helix domain protein Plav_1813 16 COG1709 COG1709, Predicted transcriptional regulator Transcription 154251374 Common - putative phage cell wall peptidase, NlpC/P60 family Plav_0918 19 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 154252502 Common - alpha/beta hydrolase fold Plav_2055 92 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154251981 Common - cytochrome c oxidase, cbb3-type, subunit III Plav_1529 79 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 154253996 Common - transcriptional regulator, MarR family Plav_3565 28 COG1846 MarR, Transcriptional regulators Transcription 154252464 Nonpathogen - hypothetical protein Plav_2017 1 None None None 154253623 Common - acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase Plav_3184 154 COG1043 LpxA, Acyl- acyl carrier protein 154251198 Common - UspA domain protein Plav_0742 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154252503 Common - amidohydrolase 2 Plav_2056 21 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 154253245 Common - Agmatine deiminase Plav_2804 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 154251143 Nonpathogen - hypothetical protein Plav_0687 6 None None None 154252791 Common - restriction modification system DNA specificity domain Plav_2346 72 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 154253096 Common - transcriptional regulator, TetR family Plav_2655 67 COG1309 AcrR, Transcriptional regulator Transcription 154251267 Common - Enoyl-CoA hydratase/isomerase Plav_0811 142 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154251059 Common - Flavin-containing monooxygenase Plav_0603 70 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154250473 Common - integral membrane sensor signal transduction histidine kinase Plav_0017 143 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253649 Common - Methylmalonyl-CoA epimerase Plav_3210 90 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154252091 Common - transcriptional regulator, TetR family Plav_1639 103 COG1309 AcrR, Transcriptional regulator Transcription 154252903 Common - protease Do Plav_2461 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 154253829 Common - hypothetical protein Plav_3393 12 None None None 154251793 Common - Rieske (2Fe-2S) domain protein Plav_1340 40 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 154252764 Common - RNA polymerase, sigma 70 subunit, RpoD Plav_2317 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 154252492 Common - hypothetical protein Plav_2045 7 None None None 154252100 Common - short-chain dehydrogenase/reductase SDR Plav_1648 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154253041 Common - methionine aminopeptidase, type I Plav_2600 242 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 154251444 Common - Taurine catabolism dioxygenase TauD/TfdA Plav_0988 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 154253022 Common - isocitrate dehydrogenase, NADP-dependent Plav_2580 63 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 154252132 Common - hypothetical protein Plav_1680 15 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 154251565 Common - hypothetical protein Plav_1111 113 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 154254082 Common - short-chain dehydrogenase/reductase SDR Plav_3651 152 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251616 Common - Tripartite ATP-independent periplasmic transporter DctQ component Plav_1162 35 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 154253149 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Plav_2708 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 154253230 Common - hypothetical protein Plav_2789 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 154252198 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Plav_1746 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 154252419 Common - Extracellular ligand-binding receptor Plav_1972 132 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 154254085 Common - transcriptional regulator, BadM/Rrf2 family Plav_3654 164 COG1959 COG1959, Predicted transcriptional regulator Transcription 154252798 Nonpathogen - hypothetical protein Plav_2353 4 None None None 154250894 Common - arsenate reductase Plav_0438 113 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 154253003 Common - flagellar basal-body rod protein FlgG Plav_2561 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 154251560 Common - hypothetical protein Plav_1106 21 COG5500 COG5500, Predicted integral membrane protein Function unknown 154252803 Common - response regulator receiver protein Plav_2358 215 COG4566 TtrR, Response regulator Signal transduction mechanisms 154251101 Common - CMP/dCMP deaminase zinc-binding Plav_0645 199 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 154252299 Common - hypothetical protein Plav_1849 6 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 154253283 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Plav_2843 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154251941 Common - acyl carrier protein Plav_1488 37 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251932 Common - glutamate 5-kinase Plav_1479 194 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 154250601 Common - orotidine 5'-phosphate decarboxylase Plav_0145 149 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 154253142 Common - NAD(+) kinase Plav_2701 236 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 154253925 Common - Pyrrolo-quinoline quinone Plav_3493 104 COG1520 COG1520, FOG: WD40-like repeat Function unknown 154251350 Common - integral membrane protein-like protein Plav_0894 14 COG5436 COG5436, Predicted integral membrane protein Function unknown 154251155 Common - chromosome segregation protein SMC Plav_0699 176 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154252505 Common - NAD(P)(+) transhydrogenase (AB-specific) Plav_2058 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 154252182 Common - preprotein translocase, SecA subunit Plav_1730 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 154253065 Common - serine O-acetyltransferase Plav_2624 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 154251227 Common - Excinuclease ABC C subunit domain protein Plav_0771 59 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 154252400 Common - Rieske (2Fe-2S) domain protein Plav_1952 91 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 154252634 Common - flagellar hook-length control protein Plav_2187 16 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 154251634 Common - hypothetical protein Plav_1180 8 None None None 154253300 Common - alpha/beta hydrolase fold Plav_2860 105 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154252571 Common - Tol-Pal system YbgF Plav_2124 102 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 154253902 Common - hypothetical protein Plav_3470 5 None None None 154250980 Common - GCN5-related N-acetyltransferase Plav_0524 34 COG0456 RimI, Acetyltransferases General function prediction only 154252033 Common - homoserine O-acetyltransferase Plav_1581 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 154254054 Common - Methionine adenosyltransferase Plav_3623 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 154253738 Nonpathogen - hypothetical protein Plav_3300 1 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 154251689 Common - hypothetical protein Plav_1236 14 None None None 154252793 Common - type I restriction-modification system, M subunit Plav_2348 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 154251163 Common - Radical SAM domain protein Plav_0707 107 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 154252959 Nonpathogen - Hpt protein Plav_2517 3 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 154251322 Nonpathogen - hypothetical protein Plav_0866 1 None None None 154251366 Common - gene transfer agent (GTA) orfg8 Plav_0910 14 None None None 154252126 Common - alpha/beta hydrolase fold Plav_1674 142 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253417 Common - DNA ligase D Plav_2977 113 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 154251329 Nonpathogen - hypothetical protein Plav_0873 1 None None None 154251093 Common - UbiD family decarboxylase Plav_0637 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 154252357 Common - acyltransferase 3 Plav_1909 86 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 154253325 Common - RDD domain containing protein Plav_2885 19 COG1714 COG1714, Predicted membrane protein/domain Function unknown 154253400 Common - molybdopterin dehydrogenase FAD-binding Plav_2960 77 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 154250905 Common - Alcohol dehydrogenase zinc-binding domain protein Plav_0449 202 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154251060 Common - transcriptional regulator, TetR family Plav_0604 57 COG1309 AcrR, Transcriptional regulator Transcription 154253509 Common - protein of unknown function DUF35 Plav_3069 60 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 154252270 Common - Lytic transglycosylase catalytic Plav_1820 103 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154250732 Common - beta-lactamase domain protein Plav_0276 49 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 154251070 Common - alanine racemase domain protein Plav_0614 56 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 154252785 Common - metallophosphoesterase Plav_2340 50 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 154250582 Common - ferredoxin Plav_0126 57 COG0633 Fdx, Ferredoxin Energy production and conversion 154254032 Nonpathogen - hypothetical protein Plav_3601 1 None None None 154253549 Common - Serine-type D-Ala-D-Ala carboxypeptidase Plav_3109 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 154252321 Common - acyl-CoA dehydrogenase domain protein Plav_1872 153 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252056 Common - Methyltransferase type 12 Plav_1604 68 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154251897 Common - arsenical-resistance protein Plav_1444 132 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 154251245 Common - 17 kDa surface antigen Plav_0789 26 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 154251113 Common - NAD(P)H dehydrogenase (quinone) Plav_0657 72 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 154253255 Common - response regulator receiver protein Plav_2814 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 154253653 Common - proton-translocating NADH-quinone oxidoreductase, chain M Plav_3214 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 154252140 Common - glycosyl transferase family 9 Plav_1688 96 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 154252427 Nonpathogen - hypothetical protein Plav_1980 1 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 154253242 Common - histidine triad (HIT) protein Plav_2801 217 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 154250723 Common - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase Plav_0267 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 154252457 Common - protein of unknown function DUF35 Plav_2010 56 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 154253452 Common - Ethyl tert-butyl ether degradation EthD Plav_3012 7 None None None 154253558 Nonpathogen - filamentous haemagglutinin family outer membrane protein Plav_3118 1 None None None 154251631 Common - hypothetical protein Plav_1177 22 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 154252665 Nonpathogen - hypothetical protein Plav_2218 1 None None None 154252117 Common - Alpha/beta hydrolase fold-3 domain protein Plav_1665 125 COG0657 Aes, Esterase/lipase Lipid metabolism 154253663 Common - NADH (or F420H2) dehydrogenase, subunit C Plav_3224 166 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 154251394 Common - Tetratricopeptide domain protein Plav_0938 59 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 154250574 Common - PAS/PAC sensor signal transduction histidine kinase Plav_0118 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154251031 Common - major facilitator superfamily MFS_1 Plav_0575 94 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 154251505 Common - TIM-barrel protein, yjbN family Plav_1050 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 154251187 Common - short-chain dehydrogenase/reductase SDR Plav_0731 225 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154252014 Common - aminotransferase class IV Plav_1562 198 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 154252815 Common - Pirin domain protein Plav_2372 132 COG1741 COG1741, Pirin-related protein General function prediction only 154252279 Common - hypothetical protein Plav_1829 16 None None None 154252513 Common - hypothetical protein Plav_2066 4 None None None 154250555 Common - CRISPR-associated protein, Csn1 family Plav_0099 20 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 154251453 Common - Biopolymer transport protein ExbD/TolR Plav_0997 133 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154250503 Common - ABC-type phosphate transport system periplasmic component-like protein Plav_0047 68 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 154251666 Nonpathogen - hypothetical protein Plav_1213 7 None None None 154251233 Common - beta-lactamase domain protein Plav_0777 89 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154251129 Common - cytochrome c oxidase subunit III Plav_0673 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 154251543 Common - phosphoglycolate phosphatase Plav_1089 194 COG0546 Gph, Predicted phosphatases General function prediction only 154251700 Common - MltA domain protein Plav_1247 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 154251488 Common - transcriptional regulator, LysR family Plav_1033 188 COG0583 LysR, Transcriptional regulator Transcription 154252342 Common - histidinol-phosphate phosphatase family protein Plav_1894 105 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 154251165 Common - hypothetical protein Plav_0709 49 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 154252714 Nonpathogen - hypothetical protein Plav_2267 2 None None None 154253264 Common - Glutathione S-transferase domain Plav_2824 54 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253199 Common - ribosomal protein S13 Plav_2758 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 154253889 Common - UspA domain protein Plav_3456 71 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154252316 Common - anti-ECFsigma factor, ChrR Plav_1867 30 COG3806 ChrR, Transcriptional activator Transcription 154252922 Common - rod shape-determining protein MreC Plav_2480 150 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 154251903 Common - malate dehydrogenase, NAD-dependent Plav_1450 195 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 154253278 Common - hypothetical protein Plav_2838 10 COG4328 COG4328, Uncharacterized protein conserved in bacteria Function unknown 154253151 Common - Methyltransferase type 11 Plav_2710 15 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154251594 Common - Endonuclease/exonuclease/phosphatase Plav_1140 77 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 154253372 Common - regulatory protein ArsR Plav_2932 74 COG0640 ArsR, Predicted transcriptional regulators Transcription 154253136 Common - L-carnitine dehydratase/bile acid-inducible protein F Plav_2695 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 154251936 Common - ribosomal protein L21 Plav_1483 200 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 154252749 Common - Ferritin Dps family protein Plav_2302 132 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 154252826 Common - Amidohydrolase 3 Plav_2383 102 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 154253410 Common - putative multicomponent Na+-H+ antiporter subunit A Plav_2970 16 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 154252897 Nonpathogen - hypothetical protein Plav_2455 2 None None None 154253107 Common - nitrogen-fixing NifU domain protein Plav_2666 50 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 154251482 Common - protein of unknown function DUF35 Plav_1027 19 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 154250884 Common - hypothetical protein Plav_0428 6 None None None 154251403 Common - FAD dependent oxidoreductase Plav_0947 51 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 154253865 Common - hypothetical protein Plav_3429 22 None None None 154251718 Common - Lysine exporter protein (LYSE/YGGA) Plav_1265 108 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 154251077 Common - hypothetical protein Plav_0621 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 154253249 Common - Domain of unknown function DUF1849 Plav_2808 19 None None None 154252914 Common - transcriptional regulator, MarR family Plav_2472 118 COG1846 MarR, Transcriptional regulators Transcription 154253297 Common - Methyltransferase type 11 Plav_2857 155 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154253409 Common - Na+/H+ antiporter MnhB subunit-related protein Plav_2969 39 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 154251220 Common - short-chain dehydrogenase/reductase SDR Plav_0764 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154250877 Common - choline/carnitine/betaine transporter Plav_0421 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 154252610 Nonpathogen - hypothetical protein Plav_2163 1 None None None 154251529 Common - luciferase family protein Plav_1074 114 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 154251974 Common - methionine-R-sulfoxide reductase Plav_1522 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 154253613 Common - GCN5-related N-acetyltransferase Plav_3174 33 COG3153 COG3153, Predicted acetyltransferase General function prediction only 154253482 Common - Amidase Plav_3042 218 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154253745 Common - glucose-1-phosphate thymidylyltransferase Plav_3308 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 154251132 Common - Carboxypeptidase Taq Plav_0676 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 154250927 Common - hypothetical protein Plav_0471 5 None None None 154251945 Common - Histidine ammonia-lyase Plav_1493 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 154252066 Common - cation transporter Plav_1614 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 154251282 Common - 2-nitropropane dioxygenase NPD Plav_0826 111 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154253017 Common - flagellar biosynthetic protein FlhB Plav_2575 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 154252702 Common - GTP-binding protein YchF Plav_2255 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 154253626 Common - outer membrane chaperone Skp (OmpH) Plav_3187 31 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 154252292 Common - P-type conjugative transfer protein TrbG Plav_1842 50 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 154251478 Common - protein of unknown function DUF1302 Plav_1023 18 None None None 154250697 Common - glutathione S-transferase, N-terminal domain protein Plav_0241 66 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251418 Common - transcriptional regulator, MarR family Plav_0962 26 COG1846 MarR, Transcriptional regulators Transcription 154252245 Common - Enoyl-CoA hydratase/isomerase Plav_1794 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154252870 Common - acyltransferase 3 Plav_2428 81 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 154251120 Nonpathogen - Cupin 2 conserved barrel domain protein Plav_0664 4 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 154251467 Nonpathogen - hypothetical protein Plav_1011 6 None None None 154251658 Common - replication protein A Plav_1204 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 154253576 Common - lipoic acid synthetase Plav_3136 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 154251157 Common - A/G-specific adenine glycosylase Plav_0701 228 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 154253693 Common - Enoyl-CoA hydratase/isomerase Plav_3255 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253393 Common - short-chain dehydrogenase/reductase SDR Plav_2953 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154251036 Common - 2-nitropropane dioxygenase NPD Plav_0580 146 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154253800 Common - ribosomal protein L9 Plav_3363 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 154250680 Nonpathogen - hypothetical protein Plav_0224 1 None None None 154253290 Common - acyl-CoA thioesterase II Plav_2850 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 154253436 Common - polysaccharide biosynthesis protein Plav_2996 44 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 154250864 Common - ApaG domain protein Plav_0408 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 154252302 Common - class II aldolase/adducin family protein Plav_1852 54 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 154250687 Common - peptidase A24A prepilin type IV Plav_0231 16 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154251684 Common - pentapeptide repeat protein Plav_1231 108 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 154253233 Common - iron-containing alcohol dehydrogenase Plav_2792 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 154253281 Common - Holliday junction resolvase YqgF Plav_2841 166 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 154251877 Common - 3-isopropylmalate dehydratase, small subunit Plav_1424 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 154252450 Nonpathogen - hypothetical protein Plav_2003 1 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 154253213 Common - Carbamoyl-phosphate synthase L chain ATP-binding Plav_2772 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 154252241 Common - 4-oxalocrotonate decarboxylase Plav_1790 64 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 154252383 Common - integral membrane sensor signal transduction histidine kinase Plav_1935 222 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 154253527 Common - AMP-dependent synthetase and ligase Plav_3087 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154251369 Common - hypothetical protein Plav_0913 11 None None None 154252709 Common - prolipoprotein diacylglyceryl transferase Plav_2262 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 154251017 Common - Amidohydrolase 3 Plav_0561 76 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 154253494 Common - queuine tRNA-ribosyltransferase Plav_3054 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 154252647 Nonpathogen - hypothetical protein Plav_2200 1 None None None 154251425 Common - Methyltransferase type 12 Plav_0969 39 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154252268 Common - hypothetical protein Plav_1818 24 None None None 154251420 Common - acyl-CoA dehydrogenase domain protein Plav_0964 137 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252522 Common - sulfate ABC transporter, inner membrane subunit CysT Plav_2075 216 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 154252373 Common - sugar transferase Plav_1925 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 154251652 Common - Lytic transglycosylase catalytic Plav_1198 143 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154253711 Common - protein of unknown function DUF583 Plav_3273 71 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 154251387 Common - putative ribonuclease BN Plav_0931 128 COG1295 Rbn, Predicted membrane protein Function unknown 154252082 Common - acyltransferase 3 Plav_1630 28 COG4763 COG4763, Predicted membrane protein Function unknown 154253729 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Plav_3291 178 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 154252627 Common - two component, sigma54 specific, transcriptional regulator, Fis family Plav_2180 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154253318 Common - Excinuclease ABC C subunit domain protein Plav_2878 40 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 154251433 Common - putative flavin-binding monooxygenase Plav_0977 70 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154252309 Common - aldehyde dehydrogenase Plav_1859 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154251139 Common - Redoxin domain protein Plav_0683 85 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154252527 Common - protein of unknown function DUF465 Plav_2080 12 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 154250533 Common - Flp/Fap pilin component Plav_0077 13 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 154250477 Common - protein of unknown function DUF1052 Plav_0021 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 154253634 Common - translation elongation factor Ts Plav_3195 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 154251866 Common - signal recognition particle-docking protein FtsY Plav_1413 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 154252775 Nonpathogen - hypothetical protein Plav_2328 1 COG5373 COG5373, Predicted membrane protein Function unknown 154253924 Common - small GTP-binding protein Plav_3492 224 COG1160 COG1160, Predicted GTPases General function prediction only 154253192 Common - ribosomal protein L6 Plav_2751 241 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 154253640 Common - Activator of Hsp90 ATPase 1 family protein Plav_3201 56 COG3832 COG3832, Uncharacterized conserved protein Function unknown 154251523 Common - Na+ dependent nucleoside transporter domain protein Plav_1068 65 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 154251690 Common - Imidazoleglycerol-phosphate dehydratase Plav_1237 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 154250758 Common - protein of unknown function DUF547 Plav_0302 24 None None None 154252658 Common - alpha/beta hydrolase fold Plav_2211 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253722 Common - hypothetical protein Plav_3284 33 COG4325 COG4325, Predicted membrane protein Function unknown 154252218 Common - AMP-dependent synthetase and ligase Plav_1766 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154251852 Common - ABC-type uncharacterized transport system involved in gliding motility auxiliary component protein Plav_1399 21 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 154251269 Common - Cyclohexanone monooxygenase Plav_0813 70 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154252557 Common - protein of unknown function DUF710 Plav_2110 38 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 154253955 Nonpathogen - hypothetical protein Plav_3523 10 None None None 154252384 Common - protein of unknown function DUF368 Plav_1936 50 COG2035 COG2035, Predicted membrane protein Function unknown 154253556 Nonpathogen - hypothetical protein Plav_3116 1 None None None 154250853 Common - phosphate ABC transporter, ATPase subunit Plav_0397 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 154252544 Common - Arylesterase Plav_2097 3 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 154253684 Common - anion transporter Plav_3246 100 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 154251449 Common - hypothetical protein Plav_0993 18 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 154250616 Common - response regulator receiver protein Plav_0160 30 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154251874 Common - tRNA (guanine-N1)-methyltransferase Plav_1421 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 154250824 Nonpathogen - hypothetical protein Plav_0368 2 None None None 154253365 Common - putative transcriptional regulator, MerR family Plav_2925 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 154251918 Common - ATP synthase F1, beta subunit Plav_1465 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 154253781 Common - glycosyl transferase family 2 Plav_3344 180 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 154253334 Common - 6-phosphogluconate dehydrogenase NAD-binding Plav_2894 192 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 154252166 Common - heat shock protein DnaJ domain protein Plav_1714 77 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154251953 Common - 3-oxoacyl-(acyl-carrier-protein) reductase, putative Plav_1501 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154250968 Common - hypothetical protein Plav_0512 12 None None None 154250705 Common - extracellular solute-binding protein family 5 Plav_0249 158 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 154252962 Common - ferredoxin Plav_2520 66 COG0633 Fdx, Ferredoxin Energy production and conversion 154252179 Common - Epoxide hydrolase domain protein Plav_1727 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154250497 Common - hypothetical protein Plav_0041 4 None None None 154252594 Common - 2-nitropropane dioxygenase NPD Plav_2147 111 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154252969 Common - hypothetical protein Plav_2527 30 COG4544 COG4544, Uncharacterized conserved protein Function unknown 154250524 Common - Polypeptide-transport-associated domain protein ShlB-type Plav_0068 55 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 154250710 Common - NUDIX hydrolase Plav_0254 109 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 154252988 Common - transcriptional regulator, TetR family Plav_2546 84 COG1309 AcrR, Transcriptional regulator Transcription 154251969 Nonpathogen - hypothetical protein Plav_1517 1 None None None 154252235 Common - transcriptional regulator, TetR family Plav_1784 12 COG1309 AcrR, Transcriptional regulator Transcription 154251834 Common - hypothetical protein Plav_1381 30 None None None 154251721 Common - transcriptional regulator, LysR family Plav_1268 176 COG0583 LysR, Transcriptional regulator Transcription 154251087 Common - peptidase U62 modulator of DNA gyrase Plav_0631 149 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 154253669 Common - ATP-dependent Clp protease, ATP-binding subunit ClpX Plav_3231 221 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 154252978 Common - conserved hypothetical protein; K09989 hypothetical protein Plav_2536 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 154250465 Common - drug resistance transporter, Bcr/CflA subfamily Plav_0009 225 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154253647 Common - Xanthine/uracil/vitamin C permease Plav_3208 134 COG2252 COG2252, Permeases General function prediction only 154252044 Common - phospholipid/glycerol acyltransferase Plav_1592 179 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 154251042 Common - putative flavin-binding monooxygenase Plav_0586 79 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154251289 Common - hypothetical protein Plav_0833 8 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 154253185 Common - ribosomal protein L29 Plav_2744 133 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 154250866 Common - 2-deoxycytidine 5-triphosphate deaminase Plav_0410 33 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 154252223 Common - acyl-CoA dehydrogenase domain protein Plav_1771 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252420 Common - inner-membrane translocator Plav_1973 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 154250485 Common - cytochrome P450 Plav_0029 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154250656 Common - domain of unknown function DUF1730 Plav_0200 131 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 154250495 Common - 8-amino-7-oxononanoate synthase Plav_0039 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 154251496 Nonpathogen - hypothetical protein Plav_1041 1 None None None 154251145 Common - glycine cleavage system H protein Plav_0689 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 154253515 Nonpathogen - hypothetical protein Plav_3075 5 None None None 154250979 Common - protein tyrosine phosphatase Plav_0523 91 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 154251894 Common - regulatory protein ArsR Plav_1441 55 COG0640 ArsR, Predicted transcriptional regulators Transcription 154252757 Common - protein of unknown function DUF1022 Plav_2310 21 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 154252255 Common - protein of unknown function DUF35 Plav_1804 53 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 154250763 Common - glycoside hydrolase 15-related Plav_0307 70 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 154252023 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Plav_1571 171 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 154250934 Common - acyl-CoA dehydrogenase domain protein Plav_0478 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154252696 Common - glutathione peroxidase Plav_2249 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 154252094 Common - arsenate reductase and related Plav_1642 93 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 154253465 Common - chromosome segregation and condensation protein ScpA Plav_3025 111 COG1354 COG1354, Uncharacterized conserved protein Function unknown 154251880 Common - integral membrane sensor signal transduction histidine kinase Plav_1427 232 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 154251600 Common - TonB family protein Plav_1146 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154251692 Common - 20S proteasome A and B subunits Plav_1239 150 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 154251185 Common - pyruvate, phosphate dikinase Plav_0729 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 154251610 Common - hypothetical protein Plav_1156 7 None None None 154251500 Nonpathogen - hypothetical protein Plav_1045 1 None None None 154253295 Common - MscS Mechanosensitive ion channel Plav_2855 44 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154251756 Common - ammonium transporter Plav_1303 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 154250835 Nonpathogen - protein of unknown function DUF1457 Plav_0379 2 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154251440 Common - Rieske (2Fe-2S) domain protein Plav_0984 88 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 154250636 Common - ABC transporter related Plav_0180 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 154253225 Common - hypothetical protein Plav_2784 21 None None None 154250896 Common - thioesterase superfamily protein Plav_0440 28 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154251673 Common - hypothetical protein Plav_1220 9 None None None 154251533 Common - acyl-CoA dehydrogenase domain protein Plav_1078 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154251381 Common - acyl-CoA dehydrogenase domain protein Plav_0925 92 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253791 Common - Guanylate kinase Plav_3354 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 154250833 Common - 2OG-Fe(II) oxygenase Plav_0377 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 154251005 Nonpathogen - hypothetical protein Plav_0549 1 None None None 154252412 Common - Glutamate synthase (ferredoxin) Plav_1964 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 154251618 Common - TRAP dicarboxylate transporter- DctP subunit Plav_1164 84 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154254063 Common - Polyribonucleotide nucleotidyltransferase Plav_3632 234 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 154250562 Nonpathogen - hypothetical protein Plav_0106 2 None None None 154253807 Common - efflux transporter, RND family, MFP subunit Plav_3370 133 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154253178 Common - ribosomal protein L4/L1e Plav_2737 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 154253059 Common - protein of unknown function DUF427 Plav_2618 49 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 154252967 Nonpathogen - hypothetical protein Plav_2525 1 None None None 154252080 Nonpathogen - hypothetical protein Plav_1628 1 None None None 154252887 Common - fumarate hydratase, class II Plav_2445 217 COG0114 FumC, Fumarase Energy production and conversion 154250913 Common - protein of unknown function DUF81 Plav_0457 60 COG0730 COG0730, Predicted permeases General function prediction only 154250481 Common - cytochrome P450 Plav_0025 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 154251411 Common - glutamine synthetase catalytic region Plav_0955 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154253288 Common - Glutathione S-transferase domain Plav_2848 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253425 Common - polar amino acid ABC transporter, inner membrane subunit Plav_2985 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 154251977 Nonpathogen - cytochrome oxidase maturation protein, cbb3-type Plav_1525 3 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 154251955 Common - secretion protein HlyD family protein Plav_1503 133 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154252297 Common - Domain of unknown function DUF1814 Plav_1847 26 COG2253 COG2253, Uncharacterized conserved protein Function unknown 154252728 Common - protein of unknown function DUF861 cupin_3 Plav_2281 43 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 154253852 Common - plasmid conserved hypothetical protein, RAQPRD Plav_3416 19 None None None 154253020 Common - recA protein Plav_2578 218 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 154252671 Nonpathogen - hypothetical protein Plav_2224 2 None None None 154250695 Common - Tetratricopeptide TPR_2 repeat protein Plav_0239 133 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 154250527 Common - response regulator receiver protein Plav_0071 20 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 154252335 Common - putative transport protein Plav_1887 58 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 154252756 Common - hypothetical protein Plav_2309 8 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 154251813 Common - protein of unknown function DUF461 Plav_1360 81 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 154252203 Common - ATPase AAA-2 domain protein Plav_1751 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 154252073 Common - crotonyl-CoA reductase Plav_1621 173 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 154251726 Common - insertion element protein Plav_1273 8 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 154250858 Common - acetylornithine and succinylornithine aminotransferase Plav_0402 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 154251010 Common - acetoacetyl-CoA synthase Plav_0554 205 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154250589 Common - alkylhydroperoxidase like protein, AhpD family Plav_0133 79 COG2128 COG2128, Uncharacterized conserved protein Function unknown 154254068 Common - ferric uptake regulator, Fur family Plav_3637 153 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154251719 Common - Carboxymethylenebutenolidase Plav_1266 108 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 154253824 Nonpathogen - hypothetical protein Plav_3388 2 None None None 154252982 Nonpathogen - hypothetical protein Plav_2540 1 None None None 154252906 Common - acetolactate synthase, large subunit, biosynthetic type Plav_2464 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 154252496 Common - hypothetical protein Plav_2049 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154253938 Common - Intracellular septation protein A Plav_3506 91 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 154251568 Common - phosphatidylserine decarboxylase related protein Plav_1114 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 154250970 Common - hypothetical protein Plav_0514 7 None None None 154253348 Common - Glycine hydroxymethyltransferase Plav_2908 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 154253855 Common - hypothetical protein Plav_3419 12 None None None 154252473 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Plav_2026 59 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 154250951 Common - MaoC domain protein dehydratase Plav_0495 57 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154250599 Common - tryptophan synthase, beta subunit Plav_0143 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 154252597 Common - putative bleomycin resistance protein Plav_2150 9 None None None 154253050 Common - class II aldolase/adducin family protein Plav_2609 95 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 154253309 Common - orotate phosphoribosyltransferase Plav_2869 121 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 154251061 Common - thioesterase superfamily protein Plav_0605 124 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 154251712 Common - hypothetical protein Plav_1259 97 COG1981 COG1981, Predicted membrane protein Function unknown 154252160 Common - hypothetical protein Plav_1708 21 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 154252230 Common - 2-nitropropane dioxygenase NPD Plav_1779 143 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154251080 Common - tetraacyldisaccharide 4'-kinase Plav_0624 128 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 154253983 Common - transcriptional regulator, LysR family Plav_3552 189 COG0583 LysR, Transcriptional regulator Transcription 154252854 Common - protein of unknown function UPF0040 Plav_2412 141 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 154253448 Common - hypothetical protein Plav_3008 19 None None None 154253908 Common - putative signal-transduction protein with CBS domains Plav_3476 56 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 154252489 Common - PAS/PAC sensor signal transduction histidine kinase Plav_2042 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154250595 Common - thioredoxin Plav_0139 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 154251465 Common - nitrite reductase, copper-containing Plav_1009 59 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 154253894 Common - putative thymidine phosphorylase Plav_3461 135 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 154253811 Common - Heavy metal transport/detoxification protein Plav_3374 44 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154253779 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Plav_3342 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 154253770 Common - Nucleoside-diphosphate kinase Plav_3333 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 154250664 Common - glycerophosphoryl diester phosphodiesterase Plav_0208 162 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 154252711 Common - Protein of unknown function DUF1790 Plav_2264 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 154253878 Common - secretion protein HlyD family protein Plav_3445 147 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154251546 Common - hypothetical protein Plav_1092 14 None None None 154251117 Common - Pil-like protein Plav_0661 18 COG5611 COG5611, Predicted nucleic-acid-binding protein, contains PIN domain General function prediction only 154252068 Common - CopG domain protein DNA-binding domain protein Plav_1616 10 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 154251520 Common - acyl-CoA dehydrogenase domain protein Plav_1065 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154250899 Common - Flavin-containing monooxygenase Plav_0443 70 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 154253859 Common - conserved hypothetical protein; putative signal peptide Plav_3423 21 None None None 154252937 Common - hypothetical protein Plav_2495 12 None None None 154253384 Nonpathogen - hypothetical protein Plav_2944 1 None None None 154251784 Common - acetate--CoA ligase Plav_1331 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154251825 Common - Methenyltetrahydrofolate cyclohydrolase Plav_1372 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 154251147 Common - glycine cleavage system P-protein Plav_0691 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 154253211 Common - ATP12 ATPase Plav_2770 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 154252046 Common - protein of unknown function DUF214 Plav_1594 33 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 154251587 Common - putative signal transduction histidine kinase Plav_1133 143 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 154251806 Common - alpha/beta hydrolase fold Plav_1353 192 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154253764 Nonpathogen - hypothetical protein Plav_3327 1 None None None 154252085 Common - HNH endonuclease Plav_1633 97 COG1403 McrA, Restriction endonuclease Defense mechanisms 154250542 Nonpathogen - hypothetical protein Plav_0086 1 None None None 154252688 Common - tRNA/rRNA methyltransferase (SpoU) Plav_2241 170 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 154251486 Common - acyl-CoA dehydrogenase domain protein Plav_1031 129 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253968 Common - Lytic transglycosylase catalytic Plav_3537 143 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154250459 Common - chromosomal replication initiator protein DnaA Plav_0003 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 154253994 Common - integrase family protein Plav_3563 110 COG0582 XerC, Integrase DNA replication, recombination, and repair 154252889 Common - peptidase M19 renal dipeptidase Plav_2447 101 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 154252806 Common - drug resistance transporter, EmrB/QacA subfamily Plav_2361 107 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154251930 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Plav_1477 184 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 154253441 Common - glycosyl transferase group 1 Plav_3001 159 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154254045 Common - GCN5-related N-acetyltransferase Plav_3614 32 COG0456 RimI, Acetyltransferases General function prediction only 154252801 Common - response regulator receiver protein Plav_2356 211 COG4566 TtrR, Response regulator Signal transduction mechanisms 154253685 Common - NADH:flavin oxidoreductase/NADH oxidase Plav_3247 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 154252707 Common - protein of unknown function DUF152 Plav_2260 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 154250882 Common - putative phosphohistidine phosphatase, SixA Plav_0426 67 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 154251196 Common - peptidase S16 lon domain protein Plav_0740 129 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 154251209 Common - AMP-dependent synthetase and ligase Plav_0753 201 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253991 Common - PglZ domain protein Plav_3560 15 None None None 154253473 Common - peptidase M23B Plav_3033 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154250549 Common - Ferric reductase domain protein transmembrane component domain Plav_0093 48 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 154252905 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Plav_2463 210 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 154253751 Common - hypothetical protein Plav_3314 22 COG3551 COG3551, Uncharacterized protein conserved in bacteria Function unknown 154251361 Common - phage prohead protease, HK97 family Plav_0905 42 COG3740 COG3740, Phage head maturation protease General function prediction only 154253086 Common - protein of unknown function DUF1457 Plav_2645 19 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 154253736 Common - response regulator receiver protein Plav_3298 192 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 154251558 Common - glutamyl-tRNA synthetase Plav_1104 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 154252700 Common - MaoC domain protein dehydratase Plav_2253 56 COG2030 MaoC, Acyl dehydratase Lipid metabolism 154250989 Common - transcriptional regulator, TetR family Plav_0533 108 COG1309 AcrR, Transcriptional regulator Transcription 154251510 Common - uroporphyrin-III C-methyltransferase Plav_1055 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 154251968 Common - protein of unknown function DUF1458 Plav_1516 47 COG3360 COG3360, Uncharacterized conserved protein Function unknown 154253120 Common - chromate transporter, chromate ion transporter (CHR) family Plav_2679 107 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 154250789 Nonpathogen - hypothetical protein Plav_0333 3 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 154252363 Common - polysaccharide pyruvyl transferase Plav_1915 20 COG5039 COG5039, Exopolysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 154253614 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Plav_3175 178 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 154252010 Nonpathogen - Sporulation domain protein Plav_1558 1 None None None 154251103 Common - Glutathione S-transferase domain Plav_0647 89 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252134 Nonpathogen - hypothetical protein Plav_1682 1 None None None 154253114 Nonpathogen - hypothetical protein Plav_2673 8 None None None 154250566 Common - peptidase M20 Plav_0110 192 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 154251947 Common - hypothetical protein Plav_1495 12 None None None 154253098 Common - transcriptional regulator, TetR family Plav_2657 33 COG1309 AcrR, Transcriptional regulator Transcription 154252466 Common - glutathione S-transferase, N-terminal domain Plav_2019 17 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154252143 Common - nuclease (SNase domain protein) Plav_1691 25 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 154251515 Common - acyl-CoA dehydrogenase domain protein Plav_1060 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 154253874 Common - Integrase catalytic region Plav_3440 135 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 154254087 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Plav_3656 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 154253144 Common - molybdenum cofactor biosynthesis protein A Plav_2703 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 154251216 Common - glucose sorbosone dehydrogenase Plav_0760 122 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 154252409 Common - branched-chain amino acid transport Plav_1961 37 COG4392 COG4392, Predicted membrane protein Function unknown 154250812 Common - Rhodanese domain protein Plav_0356 88 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 154252569 Common - Tol-Pal system beta propeller repeat TolB Plav_2122 163 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 154250826 Common - aminoglycoside phosphotransferase Plav_0370 59 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 154251337 Nonpathogen - hypothetical protein Plav_0881 1 None None None 154252125 Common - DSBA oxidoreductase Plav_1673 24 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 154252667 Common - putative glutathione S-transferase Plav_2220 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154253541 Common - major facilitator superfamily MFS_1 Plav_3101 59 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 154252006 Common - prevent-host-death family protein Plav_1554 10 None None None 154252877 Common - ribosomal L11 methyltransferase Plav_2435 178 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 154253184 Common - ribosomal protein L16 Plav_2743 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 154250991 Common - transcriptional regulator, GntR family Plav_0535 124 COG1802 GntR, Transcriptional regulators Transcription 154251258 Common - transcriptional regulator, MarR family Plav_0802 112 COG1846 MarR, Transcriptional regulators Transcription 154251303 Nonpathogen - OmpA/MotB domain protein Plav_0847 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154250941 Common - glutathione S-transferase Plav_0485 9 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 154251590 Common - amidohydrolase 2 Plav_1136 20 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 154252780 Nonpathogen - hypothetical protein Plav_2335 3 None None None 154252960 Common - FAD dependent oxidoreductase Plav_2518 96 COG0579 COG0579, Predicted dehydrogenase General function prediction only 154251760 Common - Amidase Plav_1307 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154253454 Common - Antibiotic biosynthesis monooxygenase Plav_3014 21 COG1359 COG1359, Uncharacterized conserved protein Function unknown 154252607 Common - HipA domain protein Plav_2160 56 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 154251345 Common - Sulfite reductase (ferredoxin) Plav_0889 170 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 154251320 Common - Saccharopine dehydrogenase Plav_0864 15 COG3268 COG3268, Uncharacterized conserved protein Function unknown 154251312 Common - Citrate synthase Plav_0856 194 COG0372 GltA, Citrate synthase Energy production and conversion 154250998 Common - 1,4-alpha-glucan branching enzyme Plav_0542 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 154252516 Common - rpsU-divergently transcribed protein Plav_2069 26 COG5590 COG5590, Uncharacterized conserved protein Function unknown 154251176 Common - Tetratricopeptide TPR_2 repeat protein Plav_0720 147 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 154252152 Common - multi-sensor signal transduction histidine kinase Plav_1700 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154253381 Common - plasmid maintenance system killer Plav_2941 59 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 154250611 Common - Thiolase Plav_0155 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 154253005 Common - flagellar basal body-associated protein FliL Plav_2563 20 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 154253593 Common - Phytanoyl-CoA dioxygenase Plav_3154 13 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 154250881 Common - extracellular solute-binding protein family 3 Plav_0425 81 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154253345 Common - 5-aminolevulinic acid synthase Plav_2905 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 154252106 Nonpathogen - hypothetical protein Plav_1654 1 None None None 154252308 Common - FAD dependent oxidoreductase Plav_1858 77 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 154250621 Common - Amidase Plav_0165 209 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154253775 Common - permease YjgP/YjgQ family protein Plav_3338 110 COG0795 COG0795, Predicted permeases General function prediction only 154254009 Common - GrpE protein Plav_3578 223 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 154253946 Common - hypothetical protein Plav_3514 9 None None None 154252880 Common - hypothetical protein Plav_2438 30 COG0824 FcbC, Predicted thioesterase General function prediction only 154254077 Common - UBA/THIF-type NAD/FAD binding protein Plav_3646 219 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 154250809 Nonpathogen - hypothetical protein Plav_0353 1 None None None 154253111 Common - Activator of Hsp90 ATPase 1 family protein Plav_2670 16 COG3832 COG3832, Uncharacterized conserved protein Function unknown 154251260 Common - AMP-dependent synthetase and ligase Plav_0804 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154253961 Common - hypothetical protein Plav_3530 24 None None None 154250792 Nonpathogen - nucleoside 2-deoxyribosyltransferase Plav_0336 9 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 154250644 Common - heat shock protein Hsp20 Plav_0188 68 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 154250753 Common - acetylglutamate kinase Plav_0297 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 154250553 Common - CRISPR-associated protein Cas2 Plav_0097 21 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 154251763 Common - protein of unknown function DUF343 Plav_1310 100 COG2835 COG2835, Uncharacterized conserved protein Function unknown 154253240 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Plav_2799 55 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 154252560 Common - hypothetical protein Plav_2113 4 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 154253077 Common - Enoyl-CoA hydratase/isomerase Plav_2636 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 154253038 Common - adenylosuccinate lyase Plav_2597 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 154252787 Nonpathogen - hypothetical protein Plav_2342 2 None None None 154251211 Common - thiamine pyrophosphate protein domain protein TPP-binding Plav_0755 125 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 154251191 Nonpathogen - hypothetical protein Plav_0735 1 None None None 154252523 Common - phosphate-selective porin O and P Plav_2076 28 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 154253601 Common - putative transmembrane anti-sigma factor Plav_3162 10 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 154253158 Common - glutamine synthetase catalytic region Plav_2717 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154253619 Common - glutamyl-tRNA synthetase Plav_3180 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 154250737 Common - Carboxymuconolactone decarboxylase Plav_0281 45 COG2128 COG2128, Uncharacterized conserved protein Function unknown 154252288 Common - AAA ATPase Plav_1838 61 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 154251200 Common - Beta-ketoacyl-acyl-carrier-protein synthase I Plav_0744 203 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 154253679 Common - phospholipase/Carboxylesterase Plav_3241 77 COG0400 COG0400, Predicted esterase General function prediction only 154251545 Common - GCN5-related N-acetyltransferase Plav_1091 38 COG3393 COG3393, Predicted acetyltransferase General function prediction only 154251922 Nonpathogen - hypothetical protein Plav_1469 2 None None None 154252538 Common - twin-arginine translocation pathway signal Plav_2091 34 COG2930 COG2930, Uncharacterized conserved protein Function unknown 154253957 Nonpathogen - hypothetical protein Plav_3525 1 None None None