Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence NC_009717 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 154243819 Common - hypothetical protein Xaut_4954 20 None None None 154243893 Common - 2-nitropropane dioxygenase NPD Xaut_5032 33 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154243834 Common - protein of unknown function DUF1419 Xaut_4971 8 None None None 154243881 Common - LAO/AO transport system ATPase Xaut_5020 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 154243844 Common - hypothetical protein Xaut_4981 6 None None None 154243918 Common - hypothetical protein Xaut_5057 8 None None None 154243678 Common - protein of unknown function DUF1403 Xaut_4799 9 None None None 154243823 Common - hypothetical protein Xaut_4960 14 COG5591 COG5591, Uncharacterized conserved protein Function unknown 154243753 Common - Rhodanese domain protein Xaut_4882 9 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 154243704 Nonpathogen - hypothetical protein Xaut_4829 1 None None None 154243795 Common - acriflavin resistance protein Xaut_4928 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154243926 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Xaut_5065 242 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 154243872 Nonpathogen - hypothetical protein Xaut_5011 2 None None None 154243710 Common - Isoprenylcysteine carboxyl methyltransferase Xaut_4835 27 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 154243806 Nonpathogen - hypothetical protein Xaut_4940 1 None None None 154243732 Nonpathogen - Toluene-4-monooxygenase system B Xaut_4858 5 None None None 154243851 Nonpathogen - hypothetical protein Xaut_4989 1 None None None 154243790 Nonpathogen - hypothetical protein Xaut_4923 5 None None None 154243722 Common - copper-translocating P-type ATPase Xaut_4847 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154243883 Common - carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Xaut_5022 181 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 154243941 Common - P-type conjugative transfer protein VirB9 Xaut_5080 42 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 154243865 Common - Ti-type conjugative transfer relaxase TraA Xaut_5003 81 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 154243725 Common - transposase IS3/IS911 family protein Xaut_4851 54 None None None 154243879 Common - cobalamin B12-binding domain protein Xaut_5018 109 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 154243828 Common - oxidoreductase FAD/NAD(P)-binding domain protein Xaut_4965 79 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 154243686 Common - Recombinase Xaut_4807 55 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 154243739 Common - 2-hydroxypropyl-CoM lyase Xaut_4865 132 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 154243824 Common - two component transcriptional regulator, winged helix family Xaut_4961 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154243901 Common - putative phenylacetate-CoA ligase Xaut_5040 94 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 154243784 Common - ABC transporter related Xaut_4915 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154243696 Common - transposase IS3/IS911 family protein Xaut_4820 13 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243916 Common - 1-aminocyclopropane-1-carboxylate deaminase Xaut_5055 63 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 154243673 Common - PilT protein domain protein Xaut_4793 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 154243681 Nonpathogen - hypothetical protein Xaut_4802 1 None None None 154243763 Common - hypothetical protein Xaut_4892 8 None None None 154243842 Nonpathogen - hypothetical protein Xaut_4979 3 None None None 154243935 Common - short-chain dehydrogenase/reductase SDR Xaut_5074 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154243723 Common - major facilitator superfamily MFS_1 Xaut_4848 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154243870 Common - hypothetical protein Xaut_5009 27 COG5642 COG5642, Uncharacterized conserved protein Function unknown 154243849 Common - phage integrase family protein Xaut_4986 14 None None None 154243886 Common - aminotransferase class I and II Xaut_5025 165 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 154243928 Common - fumarate lyase Xaut_5067 222 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 154243780 Common - Isoprenylcysteine carboxyl methyltransferase Xaut_4910 27 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 154243768 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Xaut_4898 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 154243804 Common - hypothetical protein Xaut_4938 7 COG4916 COG4916, Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain Function unknown 154243751 Common - Bilirubin oxidase Xaut_4880 126 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 154243891 Common - transcriptional regulator, BadM/Rrf2 family Xaut_5030 157 COG1959 COG1959, Predicted transcriptional regulator Transcription 154243896 Common - hypothetical protein Xaut_5035 36 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 154243860 Common - addiction module toxin, RelE/StbE family Xaut_4998 33 COG3668 ParE, Plasmid stabilization system protein General function prediction only 154243684 Common - hypothetical protein Xaut_4805 10 None None None 154243734 Nonpathogen - monooxygenase component MmoB/DmpM Xaut_4860 6 None None None 154243847 Common - integrase domain protein SAM domain protein Xaut_4984 17 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154243853 Common - prevent-host-death family protein Xaut_4991 5 None None None 154243826 Nonpathogen - hypothetical protein Xaut_4963 1 None None None 154243720 Common - ABC transporter related Xaut_4845 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154243745 Common - Argininosuccinate lyase Xaut_4873 215 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 154243850 Common - protein of unknown function DUF736 Xaut_4988 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 154243775 Nonpathogen - hypothetical protein Xaut_4905 1 None None None 154243809 Nonpathogen - hypothetical protein Xaut_4943 6 None None None 154243943 Common - putative type IV secretion system protein VirB7 Xaut_5082 8 None None None 154243690 Common - hypothetical protein Xaut_4813 26 None None None 154243813 Common - hypothetical protein Xaut_4948 12 COG5591 COG5591, Uncharacterized conserved protein Function unknown 154243951 Common - hypothetical protein Xaut_5090 10 None None None 154243770 Common - protein of unknown function DUF411 Xaut_4900 63 COG3019 COG3019, Predicted metal-binding protein General function prediction only 154243903 Common - LAO/AO transport system ATPase Xaut_5042 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 154243786 Nonpathogen - hypothetical protein Xaut_4917 1 None None None 154243748 Common - transcriptional regulator, LysR family Xaut_4876 191 COG0583 LysR, Transcriptional regulator Transcription 154243675 Common - Resolvase domain Xaut_4796 84 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 154243765 Common - transposase Tn3 family protein Xaut_4894 56 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 154243953 Common - prevent-host-death family protein Xaut_5092 13 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 154243940 Common - conjugation TrbI family protein Xaut_5079 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 154243888 Common - MOSC domain containing protein Xaut_5027 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 154243717 Common - transposase IS3/IS911 family protein Xaut_4842 13 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243863 Common - Conjugal transfer TraD family protein Xaut_5001 6 None None None 154243856 Common - protein of unknown function DUF1173 Xaut_4994 16 None None None 154243741 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Xaut_4867 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154243876 Common - transposase IS66 Xaut_5015 60 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243715 Common - multicopper oxidase type 2 Xaut_4840 110 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 154243861 Common - addiction module antitoxin, RelB/DinJ family Xaut_4999 27 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 154243738 Nonpathogen - DNA binding domain, excisionase family Xaut_4864 6 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 154243845 Common - ArgG Xaut_4982 8 None None None 154243682 Common - AAA ATPase central domain protein Xaut_4803 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 154243815 Common - two component transcriptional regulator, winged helix family Xaut_4950 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154243904 Common - methylmalonyl-CoA mutase, large subunit Xaut_5043 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 154243708 Common - heavy metal efflux pump, CzcA family Xaut_4833 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 154243914 Common - fumarate lyase Xaut_5053 216 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 154243929 Common - Argininosuccinate lyase Xaut_5068 215 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 154243799 Common - transcriptional regulator, MarR family Xaut_4933 33 COG1846 MarR, Transcriptional regulators Transcription 154243714 Nonpathogen - hypothetical protein Xaut_4839 2 None None None 154243794 Common - efflux transporter, RND family, MFP subunit Xaut_4927 123 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154243894 Nonpathogen - 2-nitropropane dioxygenase-like protein Xaut_5033 1 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154243701 Common - outer membrane efflux protein Xaut_4826 31 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154243838 Common - hypothetical protein Xaut_4975 9 None None None 154243777 Common - hypothetical protein Xaut_4907 22 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154243746 Common - fumarate lyase Xaut_4874 209 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 154243938 Common - hypothetical protein Xaut_5077 13 None None None 154243767 Common - hypothetical protein Xaut_4896 15 None None None 154243920 Nonpathogen - hypothetical protein Xaut_5059 2 None None None 154243955 Nonpathogen - hypothetical protein Xaut_5095 3 None None None 154243887 Common - transposase-like protein Xaut_5026 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 154243788 Common - protein of unknown function DUF900 hydrolase family protein Xaut_4919 25 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 154243698 Common - hypothetical protein Xaut_4823 22 COG5569 COG5569, Uncharacterized conserved protein Function unknown 154243874 Common - transposase IS3/IS911 family protein Xaut_5013 15 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243760 Common - Autoinducer-binding domain protein Xaut_4889 40 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 154243756 Common - hypothetical protein Xaut_4885 10 None None None 154243693 Common - transposase IS66 Xaut_4817 59 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243906 Common - transcriptional regulator, TetR family Xaut_5045 85 COG1309 AcrR, Transcriptional regulator Transcription 154243733 Common - Rieske (2Fe-2S) domain protein Xaut_4859 54 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 154243945 Common - hypothetical protein Xaut_5084 5 None None None 154243912 Nonpathogen - hypothetical protein Xaut_5051 5 None None None 154243728 Nonpathogen - hypothetical protein Xaut_4854 1 None None None 154243858 Nonpathogen - hypothetical protein Xaut_4996 1 None None None 154243836 Common - helicase domain protein Xaut_4973 39 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 154243885 Common - extracellular ligand-binding receptor Xaut_5024 51 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 154243821 Common - ParB domain protein nuclease Xaut_4956 75 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154243792 Common - transcriptional regulator, TetR family Xaut_4925 111 COG1309 AcrR, Transcriptional regulator Transcription 154243712 Common - protein of unknown function DUF1520 Xaut_4837 4 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 154243705 Nonpathogen - hypothetical protein Xaut_4830 1 None None None 154243924 Common - binding-protein-dependent transport systems inner membrane component Xaut_5063 132 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 154243680 Nonpathogen - hypothetical protein Xaut_4801 6 None None None 154243934 Common - short-chain dehydrogenase/reductase SDR Xaut_5073 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154243803 Common - UspA domain protein Xaut_4937 42 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154243689 Common - protein of unknown function DUF305 Xaut_4811 19 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 154243677 Common - Rv0623 family protein transcription factor Xaut_4798 5 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 154243769 Common - permease-like protein Xaut_4899 75 COG0628 PerM, Predicted permease General function prediction only 154243931 Nonpathogen - hypothetical protein Xaut_5070 4 None None None 154243922 Common - transposase IS116/IS110/IS902 family protein Xaut_5061 59 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243679 Common - putative transcriptional regulator Xaut_4800 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 154243744 Common - Phosphosulfolactate synthase Xaut_4872 22 COG1809 COG1809, Uncharacterized conserved protein Function unknown 154243840 Common - hypothetical protein Xaut_4977 8 None None None 154243910 Common - short-chain dehydrogenase/reductase SDR Xaut_5049 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154243781 Common - heavy metal translocating P-type ATPase Xaut_4911 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154243843 Nonpathogen - hypothetical protein Xaut_4980 1 None None None 154243771 Common - hypothetical protein Xaut_4901 25 COG5569 COG5569, Uncharacterized conserved protein Function unknown 154243919 Common - conserved hypothetical protein; putative signal peptide Xaut_5058 16 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 154243762 Common - protein of unknown function DUF1419 Xaut_4891 8 None None None 154243758 Common - Isoprenylcysteine carboxyl methyltransferase Xaut_4887 26 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 154243908 Common - 2-hydroxypropyl-CoM lyase Xaut_5047 132 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 154243695 Common - IS66 Orf2 family protein Xaut_4819 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243816 Common - integral membrane sensor signal transduction histidine kinase Xaut_4951 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154243947 Common - type IV secretion/conjugal transfer ATPase, VirB4 family Xaut_5086 66 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 154243909 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Xaut_5048 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154243812 Common - Rubrerythrin Xaut_4947 76 COG1592 COG1592, Rubrerythrin Energy production and conversion 154243776 Nonpathogen - hypothetical protein Xaut_4906 1 None None None 154243942 Common - VirB8 family protein Xaut_5081 33 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 154243783 Common - ABC-2 type transporter Xaut_4914 130 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 154243801 Common - efflux transporter, RND family, MFP subunit Xaut_4935 149 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154243936 Common - 2-oxopropyl-CoM reductase (carboxylating) Xaut_5075 6 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154243697 Common - transposase Xaut_4821 64 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243740 Nonpathogen - hypothetical protein Xaut_4866 1 None None None 154243670 Common - parB-like partition protein Xaut_4790 56 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154243747 Common - 1-aminocyclopropane-1-carboxylate deaminase Xaut_4875 67 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 154243917 Common - transcriptional regulator, LysR family Xaut_5056 192 COG0583 LysR, Transcriptional regulator Transcription 154243880 Common - Phenylacetate--CoA ligase Xaut_5019 110 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 154243830 Common - protein of unknown function DUF125 transmembrane Xaut_4967 82 COG1814 COG1814, Uncharacterized membrane protein Function unknown 154243841 Common - hypothetical protein Xaut_4978 8 None None None 154243811 Common - transcriptional regulator, HxlR family Xaut_4945 72 COG1733 COG1733, Predicted transcriptional regulators Transcription 154243892 Common - protein of unknown function DUF488 Xaut_5031 77 COG3189 COG3189, Uncharacterized conserved protein Function unknown 154243900 Common - AMP-dependent synthetase and ligase Xaut_5039 202 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 154243718 Common - transposase IS4 family protein Xaut_4843 44 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243854 Common - hypothetical protein Xaut_4992 7 None None None 154243818 Nonpathogen - hypothetical protein Xaut_4953 2 None None None 154243807 Common - mobile mystery protein B Xaut_4941 16 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 154243899 Common - ABC transporter related Xaut_5038 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 154243766 Common - RES domain protein Xaut_4895 11 COG5654 COG5654, Uncharacterized conserved protein Function unknown 154243868 Common - prevent-host-death family protein Xaut_5007 5 None None None 154243925 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Xaut_5064 79 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 154243833 Common - hypothetical protein Xaut_4970 10 None None None 154243798 Common - beta-lactamase domain protein Xaut_4932 75 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154243873 Common - hypothetical protein Xaut_5012 7 None None None 154243721 Common - secretion protein HlyD family protein Xaut_4846 122 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154243719 Common - ABC-2 type transporter Xaut_4844 133 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 154243773 Common - multicopper oxidase type 3 Xaut_4903 131 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 154243754 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 3 Xaut_4883 158 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 154243825 Common - integral membrane sensor signal transduction histidine kinase Xaut_4962 73 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154243759 Common - protein of unknown function DUF1520 Xaut_4888 5 None None None 154243724 Common - protein of unknown function DUF344 Xaut_4849 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 154243882 Common - methylmalonyl-CoA mutase, large subunit Xaut_5021 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 154243793 Common - efflux transporter, RND family, MFP subunit Xaut_4926 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154243915 Common - fumarate lyase Xaut_5054 223 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 154243944 Common - TrbL/VirB6 plasmid conjugal transfer protein Xaut_5083 38 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 154243808 Common - mobile mystery protein A Xaut_4942 13 None None None 154243902 Common - phenylacetic acid degradation protein PaaD Xaut_5041 57 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154243778 Nonpathogen - protein of unknown function DUF1520 Xaut_4908 3 None None None 154243691 Common - transposase IS3/IS911 family protein Xaut_4815 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243736 Common - Oxidoreductase FAD-binding domain protein Xaut_4862 123 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 154243699 Common - blue (type 1) copper domain protein Xaut_4824 34 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 154243672 Common - integrase family protein Xaut_4792 46 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154243864 Common - TraC family protein Xaut_5002 5 None None None 154243950 Common - transport secretion system IV, VirB1 protein Xaut_5089 22 None None None 154243687 Common - ParB domain protein nuclease Xaut_4808 68 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154243805 Common - major facilitator superfamily MFS_1 Xaut_4939 146 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154243927 Common - CoA-binding domain protein Xaut_5066 177 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 154243831 Nonpathogen - hypothetical protein Xaut_4968 1 None None None 154243796 Nonpathogen - hypothetical protein Xaut_4930 6 None None None 154243889 Common - 5-formyltetrahydrofolate cyclo-ligase Xaut_5028 98 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 154243890 Common - globin Xaut_5029 45 COG2346 COG2346, Truncated hemoglobins General function prediction only 154243871 Common - RES domain protein Xaut_5010 30 COG5654 COG5654, Uncharacterized conserved protein Function unknown 154243703 Common - cyclic nucleotide-binding protein Xaut_4828 29 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154243752 Common - protein of unknown function DUF302 Xaut_4881 43 COG3439 COG3439, Uncharacterized conserved protein Function unknown 154243785 Common - secretion protein HlyD family protein Xaut_4916 102 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 154243827 Common - hypothetical protein Xaut_4964 14 None None None 154243848 Common - hypothetical protein Xaut_4985 13 None None None 154243731 Common - methane/phenol/toluene hydroxylase Xaut_4857 19 None None None 154243866 Common - hypothetical protein Xaut_5004 19 None None None 154243937 Nonpathogen - hypothetical protein Xaut_5076 1 None None None 154243949 Common - VIRB2 type IV secretion fmaily protein Xaut_5088 18 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 154243782 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Xaut_4913 234 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 154243952 Common - hypothetical protein Xaut_5091 6 None None None 154243930 Common - Phosphosulfolactate synthase Xaut_5069 22 COG1809 COG1809, Uncharacterized conserved protein Function unknown 154243669 Common - Cobyrinic acid ac-diamide synthase Xaut_4789 199 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154243772 Common - blue (type 1) copper domain protein Xaut_4902 30 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 154243743 Common - short-chain dehydrogenase/reductase SDR Xaut_4869 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154243939 Common - P-type DNA transfer ATPase VirB11 Xaut_5078 182 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 154243913 Common - Phosphosulfolactate synthase Xaut_5052 22 COG1809 COG1809, Uncharacterized conserved protein Function unknown 154243755 Nonpathogen - Ni Fe-hydrogenase III large subunit-like protein Xaut_4884 2 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 154243692 Common - IS66 Orf2 family protein Xaut_4816 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243905 Common - cobalamin B12-binding domain protein Xaut_5044 107 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 154243787 Common - transcriptional regulator, TetR family Xaut_4918 21 COG1309 AcrR, Transcriptional regulator Transcription 154243674 Nonpathogen - hypothetical protein Xaut_4794 1 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 154243946 Common - P-type DNA transfer protein VirB5 Xaut_5085 16 None None None 154243954 Common - transposase mutator type Xaut_5093 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243709 Common - heavy metal translocating P-type ATPase Xaut_4834 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154243877 Nonpathogen - hypothetical protein Xaut_5016 7 None None None 154243716 Common - hypothetical protein Xaut_4841 44 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243729 Nonpathogen - hypothetical protein Xaut_4855 1 None None None 154243855 Common - WGR domain protein Xaut_4993 17 COG3831 COG3831, Uncharacterized conserved protein Function unknown 154243846 Common - domain of unknown function DUF1738 Xaut_4983 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 154243735 Nonpathogen - methane/phenol/toluene hydroxylase Xaut_4861 12 None None None 154243820 Nonpathogen - hypothetical protein Xaut_4955 4 None None None 154243814 Common - cytochrome B561 Xaut_4949 42 COG3658 COG3658, Cytochrome b Energy production and conversion 154243829 Common - ApbE family lipoprotein Xaut_4966 133 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 154243685 Common - hypothetical protein Xaut_4806 8 COG2378 COG2378, Predicted transcriptional regulator Transcription 154243897 Common - inner-membrane translocator Xaut_5036 102 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 154243802 Common - drug resistance transporter, Bcr/CflA subfamily Xaut_4936 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154243832 Nonpathogen - hypothetical protein Xaut_4969 8 None None None 154243839 Common - ParB domain protein nuclease Xaut_4976 24 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154243713 Common - hypothetical protein Xaut_4838 22 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 154243837 Common - RES domain protein Xaut_4974 11 COG5654 COG5654, Uncharacterized conserved protein Function unknown 154243702 Common - hypothetical protein Xaut_4827 17 None None None 154243921 Common - transposase IS116/IS110/IS902 family protein Xaut_5060 23 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243671 Common - replication protein C Xaut_4791 17 None None None 154243956 Common - transposase mutator type Xaut_5096 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243750 Common - transposase IS4 family protein Xaut_4878 19 None None None 154243932 Common - coenzyme A transferase Xaut_5071 40 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 154243683 Common - hypothetical protein Xaut_4804 31 None None None 154243706 Nonpathogen - hypothetical protein Xaut_4831 8 None None None 154243779 Nonpathogen - hypothetical protein Xaut_4909 1 None None None 154243867 Common - protein of unknown function DUF140 Xaut_5005 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 154243911 Common - short-chain dehydrogenase/reductase SDR Xaut_5050 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154243797 Common - protein of unknown function UPF0118 Xaut_4931 182 COG0628 PerM, Predicted permease General function prediction only 154243764 Common - DEAD-like helicase Xaut_4893 32 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 154243948 Common - type IV secretory pathway VirB3 family protein Xaut_5087 14 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 154243761 Common - hypothetical protein Xaut_4890 10 None None None 154243817 Common - heavy metal translocating P-type ATPase Xaut_4952 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154243774 Common - outer membrane efflux protein Xaut_4904 33 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154243694 Common - hypothetical protein Xaut_4818 15 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243757 Common - hypothetical protein Xaut_4886 16 None None None 154243907 Common - hypothetical protein Xaut_5046 7 None None None 154243789 Common - peptidase C26 Xaut_4921 122 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 154243810 Nonpathogen - hypothetical protein Xaut_4944 1 None None None 154243862 Common - Ti-type conjugative transfer system TraG Xaut_5000 57 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 154243749 Common - OmpW family protein Xaut_4877 59 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 154243933 Common - coenzyme A transferase Xaut_5072 81 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 154243730 Common - hypothetical protein Xaut_4856 19 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 154243957 Nonpathogen - hypothetical protein Xaut_5097 3 None None None 154243875 Common - IS66 Orf2 family protein Xaut_5014 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243869 Common - hypothetical protein Xaut_5008 12 None None None 154243822 Common - hypothetical protein Xaut_4959 8 None None None 154243884 Common - ATP--cobalamin adenosyltransferase Xaut_5023 116 COG2096 COG2096, Uncharacterized conserved protein Function unknown 154243742 Common - short-chain dehydrogenase/reductase SDR Xaut_4868 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154243857 Common - hypothetical protein Xaut_4995 21 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243727 Nonpathogen - hypothetical protein Xaut_4853 4 None None None 154243711 Nonpathogen - hypothetical protein Xaut_4836 1 None None None 154243800 Common - Fusaric acid resistance protein conserved region Xaut_4934 53 COG1289 COG1289, Predicted membrane protein Function unknown 154243835 Common - hypothetical protein Xaut_4972 11 None None None 154243700 Common - multicopper oxidase type 3 Xaut_4825 130 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 154243923 Common - ABC transporter related Xaut_5062 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 154243859 Nonpathogen - hypothetical protein Xaut_4997 2 None None None 154243726 Common - Integrase catalytic region Xaut_4852 122 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 154243878 Common - transcriptional regulator, GntR family Xaut_5017 138 COG1802 GntR, Transcriptional regulators Transcription 154243791 Nonpathogen - hypothetical protein Xaut_4924 2 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154243898 Common - inner-membrane translocator Xaut_5037 90 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 154243737 Common - aldehyde dehydrogenase Xaut_4863 191 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154243895 Common - ABC transporter related Xaut_5034 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 154243676 Common - PilT protein domain protein Xaut_4797 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 154243707 Common - efflux transporter, RND family, MFP subunit Xaut_4832 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154243852 Nonpathogen - hypothetical protein Xaut_4990 3 None None None 154243688 Common - RepB plasmid partition Xaut_4809 16 COG1475 Spo0J, Predicted transcriptional regulators Transcription