Clostridium botulinum A str. Hall, complete genome NC_009698 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 153934940 Common - SpoVA family protein CLC_2986 15 None None None 153935174 Common - MATE efflux family protein CLC_1892 159 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153935760 Common - putative DNA-binding protein CLC_1440 2 None None None 153935351 Common - chromate transport protein CLC_0458 112 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 153937191 Common - putative internalin CLC_3006 40 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 153935681 Common - PTS system, glucose/glucoside family, IIBC component CLC_1633 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153937751 Common - hypothetical protein CLC_1801 1 None None None 153935475 Common rpmG ribosomal protein L33 CLC_3440 86 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 153934677 Common - sensor histidine kinase CLC_3520 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936138 Common treP PTS system, trehalose-specific IIBC component CLC_1933 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153935104 Common - hypothetical protein CLC_0058 8 None None None 153937063 Common cysS cysteinyl-tRNA synthetase CLC_3450 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153935432 Common - ABC transporter, ATP-binding protein CLC_0777 227 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153936224 Common - site-specific recombinase, phage integrase family CLC_1735 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153936915 Common - degV family protein CLC_0645 57 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 153937402 Common - hypothetical protein CLC_1328 59 COG1971 COG1971, Predicted membrane protein Function unknown 153937734 Common megL methionine gamma-lyase CLC_0047 211 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153935368 Common infA translation initiation factor IF-1 CLC_3401 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 153937461 Common sfsA sugar fermentation stimulation protein CLC_0056 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 153935406 Common - sensor histidine kinase CLC_0836 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936130 Common - MATE efflux family protein CLC_2716 121 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153936743 Common udk uridine kinase CLC_2425 97 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 153937007 Common - polysaccharide biosynthesis family protein CLC_1472 22 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153936684 Common - pseudouridine synthase, RluA family CLC_1470 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 153935342 Common - hypothetical protein CLC_3206 1 None None None 153936872 Common - superoxide dismutase, Mn/Fe family CLC_0594 169 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 153937585 Common - putative transcriptional regulator CLC_1562 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 153937400 Common - hypothetical protein CLC_2379 31 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 153936365 Common fruK fructose-1-phosphate kinase CLC_1706 101 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 153935206 Common addA recombination helicase AddA CLC_0511 217 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 153936473 Common - hypothetical protein CLC_2038 6 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 153937489 Common - hypothetical protein CLC_3227 18 COG3949 COG3949, Uncharacterized membrane protein Function unknown 153935885 Pathogen - hypothetical protein CLC_0989 1 None None None 153934985 Pathogen - hypothetical protein CLC_1321 1 None None None 153937865 Common - oxidoreductase family protein CLC_2200 19 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153935422 Common - putative hydrolase CLC_2845 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 153935903 Common - electron transport complex, RnfABCDGE type, A subunit CLC_0430 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 153936826 Common aor aldehyde ferredoxin oxidoreductase, tungsten-containing CLC_1881 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 153937107 Common metF 5,10-methylenetetrahydrofolate reductase CLC_1648 161 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 153937083 Common moaA molybdenum cofactor biosynthesis protein A CLC_1885 211 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 153935265 Common cobM precorrin-4 C11-methyltransferase CLC_1003 203 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 153934701 Pathogen - hypothetical protein CLC_2130 1 None None None 153937757 Common - hypothetical protein CLC_1142 2 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 153936905 Common - ABC transporter, ATP-binding protein CLC_1874 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935743 Common - rrf2 family protein CLC_1221 163 COG1959 COG1959, Predicted transcriptional regulator Transcription 153936988 Common sdhB L-serine dehydratase, iron-sulfur-dependent, beta subunit CLC_1255 54 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 153936579 Common - hypothetical protein CLC_0952 3 None None None 153934991 Common - acetyltransferase, GNAT family CLC_2024 12 COG0456 RimI, Acetyltransferases General function prediction only 153935074 Common - hypothetical protein CLC_0834 1 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 153937345 Common - hypothetical protein CLC_1960 103 COG2962 RarD, Predicted permeases General function prediction only 153935704 Common - glycine betaine/L-proline ABC transporter, ATP-binding protein CLC_1662 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 153935898 Common - conserved hypothetical protein TIGR00250 CLC_2433 182 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 153935797 Common atpD ATP synthase F1, beta subunit CLC_0204 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 153936857 Common - putative R-2-hydroxyglutaryl-CoA dehydratase subunit CLC_3156 33 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153936084 Pathogen - hypothetical protein CLC_0115 1 None None None 153934948 Common ilvA threonine dehydratase CLC_3451 212 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 153936422 Common proS prolyl-tRNA synthetase CLC_3289 184 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153934828 Common - hypothetical protein CLC_1113 2 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 153934611 Pathogen - hypothetical protein CLC_2753 1 None None None 153934994 Common - methyl-accepting chemotaxis protein/bacterial extracellular solute-binding protein, family 5 CLC_0870 216 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153937601 Common - hypothetical protein CLC_2220 2 None None None 153934578 Common - modification methylase family protein CLC_2992 40 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 153936383 Common - radical SAM domain protein CLC_0497 65 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 153934739 Common - ErfK/YbiS/YcfS/YnhG family protein CLC_3089 71 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153937493 Common - radical SAM domain protein CLC_1943 34 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 153934808 Common - CoA-binding protein CLC_3611 24 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 153936752 Common - aminotransferase, class V CLC_1175 172 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 153936242 Common rpsQ ribosomal protein S17 CLC_3416 223 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 153936961 Common - polyA polymerase family protein CLC_2230 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 153937799 Common - hypothetical protein CLC_0644 1 None None None 153937432 Common - penicillin-binding protein CLC_2896 196 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 153936995 Common - MutS2 family protein CLC_3025 205 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 153937532 Common - HDIG domain protein CLC_3116 45 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 153937121 Common - putative transcriptional regulator CLC_0018 16 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 153936236 Pathogen - hypothetical protein CLC_2325 1 None None None 153935123 Common - exonuclease, DNA polymerase III, epsilon subunit family CLC_0314 104 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 153935395 Common - glyoxalase family protein CLC_0516 9 None None None 153936410 Common - putative oxygen-independent coproporphyrinogen III oxidase CLC_2858 209 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 153936839 Common - amino acid permease family protein CLC_2322 162 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 153936001 Common - methyl-accepting chemotaxis protein CLC_0582 137 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153936323 Common - transcriptional regulator, AbrB family CLC_2012 8 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 153937094 Common - peptidase, M16 family CLC_2258 194 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 153935956 Common - transcriptional regulator, MerR family CLC_0762 16 COG0789 SoxR, Predicted transcriptional regulators Transcription 153934901 Common - MOSC domain protein CLC_1883 36 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 153937210 Common - hypothetical protein CLC_1204 10 None None None 153936273 Common ftsH-1 ATP-dependent metalloprotease FtsH CLC_3287 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 153935757 Common - hypothetical protein CLC_1111 106 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 153937407 Pathogen - hypothetical protein CLC_3297 1 None None None 153935648 Common - hypothetical protein CLC_0549 80 COG1284 COG1284, Uncharacterized conserved protein Function unknown 153936879 Common - hypothetical protein CLC_1131 1 None None None 153935692 Common - hypothetical protein CLC_2165 9 None None None 153934730 Pathogen - hypothetical protein CLC_1675 1 None None None 153936629 Common rplE ribosomal protein L5 CLC_3413 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 153937310 Common ruvB Holliday junction DNA helicase RuvB CLC_2972 224 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 153937482 Common rplT ribosomal protein L20 CLC_3038 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 153937078 Common - iron-sulfur binding protein CLC_2145 37 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 153935513 Common - methionine ABC transporter, MUT family, ATP-binding protein CLC_1136 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 153936691 Pathogen - hypothetical protein CLC_0998 1 None None None 153935806 Common - putative anion ABC transporter, ATP-binding protein CLC_1019 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153934655 Common punA purine nucleoside phosphorylase I, inosine and guanosine-specific CLC_1807 159 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 153935700 Common - putative transcriptional regulator CLC_1940 63 COG1737 RpiR, Transcriptional regulators Transcription 153936308 Pathogen - hypothetical protein CLC_1145 1 None None None 153937521 Common thyX thymidylate synthase, flavin-dependent CLC_3448 74 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 153934935 Common - hypothetical protein CLC_0689 8 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 153935090 Common - ABC transporter, permease protein CLC_3044 3 None None None 153936454 Common - glycosyl transferase, group 1 family protein CLC_2584 102 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153936562 Common - transcriptional regulator, PadR family CLC_0145 56 COG1695 COG1695, Predicted transcriptional regulators Transcription 153936004 Common hisF imidazoleglycerol phosphate synthase, cyclase subunit CLC_1603 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 153937596 Common purN phosphoribosylglycinamide formyltransferase CLC_2772 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 153936419 Common - DNA-binding protein CLC_1972 40 COG1476 COG1476, Predicted transcriptional regulators Transcription 153935046 Common - sensory box sigma-54 dependent transcriptional regulator CLC_2344 198 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153936492 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CLC_1223 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153935585 Common - 3D/G5 domain protein CLC_0126 37 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 153935036 Common - hypothetical protein CLC_2243 21 COG2155 COG2155, Uncharacterized conserved protein Function unknown 153935765 Pathogen - hypothetical protein CLC_3079 1 None None None 153937416 Common - hypothetical protein CLC_2749 2 None None None 153935550 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CLC_2792 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153937202 Common - GGDEF domain protein CLC_1402 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153937726 Common rplC ribosomal protein L3 CLC_3425 246 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 153937543 Pathogen - hypothetical protein CLC_1679 1 None None None 153934725 Common - hypothetical protein CLC_3536 20 COG3949 COG3949, Uncharacterized membrane protein Function unknown 153936940 Common - amidohydrolase domain protein CLC_2131 181 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153934839 Common - putative cell division protein FtsX CLC_3333 120 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 153935009 Common guaA GMP synthase CLC_3237 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 153934503 Common - HAD-superfamily hydrolase, subfamily IA CLC_2732 103 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153936977 Common - hypothetical protein CLC_1251 5 None None None 153936197 Common - putative transporter CLC_1372 106 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153934955 Common pnpA polyribonucleotide nucleotidyltransferase CLC_2259 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 153936059 Common - cell cycle protein, FtsW/RodA/SpoVE family CLC_1497 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 153934721 Common - cell envelope-related transcriptional attenuator domain protein CLC_2563 63 COG1316 LytR, Transcriptional regulator Transcription 153934541 Common - hypothetical protein CLC_0342 41 COG4420 COG4420, Predicted membrane protein Function unknown 153937057 Common - putative metalloprotease CLC_0569 76 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 153937044 Common - putative cyclase CLC_1066 3 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 153937502 Common - hypothetical protein CLC_2476 115 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 153935561 Common - protein kinase CLC_2359 163 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 153937533 Common - hypothetical protein CLC_2470 107 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 153937126 Common - hypothetical protein CLC_2493 7 None None None 153936963 Common - hypothetical protein CLC_1988 4 COG0714 COG0714, MoxR-like ATPases General function prediction only 153936761 Common - putative bacT protein CLC_2458 25 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 153937140 Common - hypothetical protein CLC_0817 1 None None None 153937849 Pathogen - hypothetical protein CLC_1110 1 None None None 153935528 Pathogen - hypothetical protein CLC_1728 1 None None None 153936870 Common - xanthine dehydrogenase family protein, iron-sulfur binding subunit CLC_1325 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 153937474 Common - RecF/RecN/SMC N terminal domain protein CLC_2736 29 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 153937471 Common nth endonuclease III CLC_0265 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 153937651 Common - glutamate decarboxylase CLC_1861 66 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 153935686 Common surE acid phosphatase SurE CLC_0289 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 153935381 Common lgt prolipoprotein diacylglyceryl transferase CLC_3119 210 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 153934582 Common - hypothetical protein CLC_1035 25 COG3506 COG3506, Uncharacterized conserved protein Function unknown 153936433 Common - DNA-binding protein CLC_2944 28 COG1476 COG1476, Predicted transcriptional regulators Transcription 153936603 Common maa maltose transacetylase CLC_1167 113 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 153936968 Common - carbohydrate kinase family protein CLC_3343 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 153936378 Common - putative drug resistance ABC transporter, ATP-binding protein CLC_0765 246 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 153934589 Common - glycosyl transferase, group 2 family protein CLC_2045 103 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153936739 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CLC_1099 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 153935159 Common trmU-2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CLC_2801 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 153935998 Common cotJB spore coat peptide assembly protein CotJB CLC_1270 9 None None None 153937491 Common - polysaccharide deacetylase family protein CLC_0279 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153937384 Common ptsI phosphoenolpyruvate-protein phosphotransferase CLC_3382 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 153935814 Common mraY-1 phospho-N-acetylmuramoyl-pentapeptide-transferase CLC_0937 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 153936258 Common - hypothetical protein CLC_3318 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 153936096 Common tilS tRNA(Ile)-lysidine synthetase CLC_3490 234 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153936280 Common - aminotransferase, class V CLC_1965 151 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 153937513 Common - putative PTS system, L-ascorbate family, IIC component CLC_2094 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 153936805 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III-like protein CLC_0773 197 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 153937174 Common - MATE efflux family protein CLC_1155 155 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153937149 Common - electron transfer flavoprotein, alpha subunit/FixB family protein CLC_3107 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 153937509 Common - putative DNA-binding protein CLC_2128 25 COG1476 COG1476, Predicted transcriptional regulators Transcription 153934571 Common - hypothetical protein CLC_0788 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 153936720 Common - metallopeptidase, family M24 CLC_0402 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153937409 Common - hypothetical protein CLC_3090 11 COG0730 COG0730, Predicted permeases General function prediction only 153935154 Common - DNA-cytosine methyltransferase family protein CLC_0890 112 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 153936311 Common - hypothetical protein CLC_1232 4 None None None 153935772 Common - DNA-binding protein CLC_0400 132 COG1396 HipB, Predicted transcriptional regulators Transcription 153937372 Common - DJ-1/PfpI family protein CLC_1078 91 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 153937234 Common uppS undecaprenyl diphosphate synthase CLC_2278 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 153936069 Common - hypothetical protein CLC_2106 41 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 153935728 Common - sulfate permease, SulP family CLC_3292 172 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 153934484 Common mog molybdopterin biosynthesis enzyme Mog CLC_1888 190 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 153936620 Common - acetyltransferase, GNAT family CLC_0312 11 COG2153 ElaA, Predicted acyltransferase General function prediction only 153935294 Common - hypothetical protein CLC_2506 1 None None None 153936906 Common - hypothetical protein CLC_3335 51 COG1284 COG1284, Uncharacterized conserved protein Function unknown 153935836 Common panD aspartate 1-decarboxylase CLC_0489 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 153937853 Common feoA-1 ferrous iron transport protein A CLC_0871 12 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 153935557 Common apt adenine phosphoribosyltransferase CLC_2962 178 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153937674 Common pgk phosphoglycerate kinase CLC_0283 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 153937551 Common - hypothetical protein CLC_3042 14 None None None 153936866 Common - putative sugar ABC transporter, ATP-binding protein CLC_0276 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 153936953 Common - ferredoxin, 4Fe-4S CLC_0107 192 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 153936508 Common nusG transcription termination/antitermination factor NusG CLC_3438 215 COG0250 NusG, Transcription antiterminator Transcription 153936645 Common - hypothetical protein CLC_2904 1 None None None 153937801 Common - hypothetical protein CLC_2949 2 None None None 153935787 Common - putative sensory box sigma-54 dependent transcriptional regulator CLC_0046 169 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153934487 Common hisG ATP phosphoribosyltransferase CLC_1597 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 153936165 Common - hypothetical protein CLC_0911 39 COG2320 GrpB, Uncharacterized conserved protein Function unknown 153934834 Common - hypothetical protein CLC_0558 20 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 153936618 Common - spore germination protein CLC_0171 15 None None None 153936291 Pathogen - hypothetical protein CLC_1085 1 None None None 153935789 Common - hypothetical protein CLC_3544 1 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 153937737 Common acoB TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit CLC_1657 206 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 153935777 Common xpt-2 xanthine phosphoribosyltransferase CLC_1188 64 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153935215 Common ribD riboflavin biosynthesis protein RibD CLC_2765 230 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 153935894 Common - metallo-beta-lactamase family protein CLC_2959 219 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153937071 Common def-2 peptide deformylase CLC_2365 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 153934814 Common - transcriptional regulator, MarR family CLC_1069 14 COG1846 MarR, Transcriptional regulators Transcription 153935829 Common - putative ABC transporter, permease protein CLC_1417 7 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 153937275 Common - YaiI/YqxD family protein CLC_3220 77 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 153935921 Common - SEC-C domain protein CLC_3548 75 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 153935893 Common - hypothetical protein CLC_1710 14 None None None 153936747 Common - putative glycosyl hydrolase CLC_1134 23 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 153936655 Common - hypothetical protein CLC_1771 7 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 153936261 Common eutE acetaldehyde dehydrogenase (acetylating) CLC_2050 156 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153936375 Common - etratricopeptide repeat protein CLC_1424 2 None None None 153935737 Common - D-alanyl-D-alanine carboxypeptidase family protein CLC_1086 39 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153934697 Common - hypothetical protein CLC_0509 4 None None None 153935000 Common - transcriptional regulator, GntR family CLC_1143 154 COG2186 FadR, Transcriptional regulators Transcription 153936572 Common - GTP-binding protein CLC_2290 101 COG1161 COG1161, Predicted GTPases General function prediction only 153936980 Common - hypothetical protein CLC_3132 2 None None None 153936558 Common - tetratricopeptide repeat/DNA binding domain protein CLC_0441 39 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 153935067 Common alr-3 alanine racemase CLC_3341 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 153937021 Common - hypothetical protein CLC_3631 2 None None None 153935242 Common - peptidase, M16 family CLC_3086 198 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 153934527 Common - iron chelate uptake ABC transporter, FeCT family, solute-binding protein CLC_1375 165 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153935289 Common - hypothetical protein CLC_2797 80 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153937232 Common - aldehyde dehydrogenase family protein CLC_1151 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153936399 Common - heat shock protein CLC_1703 158 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 153936442 Common - putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase CLC_3065 230 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 153937648 Pathogen - hypothetical protein CLC_0500 1 None None None 153935147 Common efp translation elongation factor P CLC_1841 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 153935945 Pathogen - hypothetical protein CLC_1378 1 None None None 153937646 Pathogen - hypothetical protein CLC_3014 1 None None None 153934776 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CLC_1510 213 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 153937635 Common rpoD RNA polymerase sigma factor RpoD CLC_2833 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 153936271 Common tupB tungstate ABC transporter, permease protein CLC_1890 178 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 153936351 Common srlD sorbitol-6-phosphate 2-dehydrogenase CLC_3358 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153936318 Common - hypothetical protein CLC_0251 72 COG2323 COG2323, Predicted membrane protein Function unknown 153937428 Common - hypothetical protein CLC_3624 5 None None None 153936098 Common - hypothetical protein CLC_2185 26 None None None 153934477 Common rpsR ribosomal protein S18 CLC_3625 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 153937745 Pathogen - hypothetical protein CLC_2112 1 None None None 153936663 Common - UBA/TS-N domain protein CLC_2839 4 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 153935227 Common - small acid-soluble spore protein CLC_3055 7 None None None 153935488 Common - transcriptional regulator, GntR family CLC_1247 45 COG1725 COG1725, Predicted transcriptional regulators Transcription 153935659 Common - electron transfer flavoprotein, alpha subunit/FixB family protein CLC_1061 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 153936677 Common - hypothetical protein CLC_1264 7 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 153934885 Common - hypothetical protein CLC_0388 6 None None None 153935030 Common - protein phosphatase family protein CLC_2360 134 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 153936890 Common - hypothetical protein CLC_1524 1 None None None 153937211 Common pyrH uridylate kinase CLC_2280 234 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 153936172 Common - polysaccharide deacetylase family protein CLC_0116 117 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153936888 Pathogen - hypothetical protein CLC_2633 1 None None None 153936702 Common lysS lysyl-tRNA synthetase CLC_3482 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 153936150 Common - high-affinity branched-chain amino acid ABC transporter, permease protein CLC_0528 165 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153935213 Common - conserved hypothetical protein TIGR00486 CLC_2830 155 COG0327 COG0327, Uncharacterized conserved protein Function unknown 153935533 Common - bacterial transferase, hexapeptide repeat family CLC_1996 185 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 153936709 Common cheV chemotaxis protein CheV CLC_1720 113 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 153935834 Common - ArsC family protein CLC_1118 63 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 153934643 Common - conserved hypothetical protein TIGR00103 CLC_0052 3 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 153935481 Common - copper-translocating P-type ATPase CLC_1342 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153937868 Common - hypothetical protein CLC_1075 20 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 153935948 Common glyS glycyl-tRNA synthetase CLC_3481 87 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 153937027 Common - hypothetical protein CLC_1241 50 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 153935872 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein CLC_0264 103 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 153936745 Common - hypothetical protein CLC_2811 4 None None None 153937817 Common - glycosyl transferase, group 2 family protein CLC_2600 120 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153936091 Common - electron transport complex, RnfABCDGE type, C subunit CLC_0426 130 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 153936716 Common - helicase, SNF2/RAD54 family CLC_1693 135 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 153934866 Common - sigma-54 dependent transcriptional regulator CLC_2786 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153937293 Common - putative R-2-hydroxyglutaryl-CoA dehydratase, beta subunit CLC_2140 35 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153934538 Common - dinitrogenase iron-molybdenum cofactor family protein CLC_1347 18 COG1433 COG1433, Uncharacterized conserved protein Function unknown 153935082 Common - transcriptional regulator, MarR family CLC_1154 52 COG1846 MarR, Transcriptional regulators Transcription 153936255 Common - hypothetical protein CLC_2312 2 None None None 153936321 Pathogen - putative lipoprotein CLC_2686 1 None None None 153935232 Common - putative adenylyl cyclase CyaB CLC_0247 3 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 153936895 Common - electron transfer flavoprotein, alpha subunit/FixB family protein CLC_3228 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 153934786 Common - putative cell division protein FtsA CLC_1467 120 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 153934964 Common - hypothetical protein CLC_1998 9 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153937308 Common - putative ferrichrome ABC transporter, ferrichrome-binding protein CLC_0740 64 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153937251 Common - hypothetical protein CLC_3567 17 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 153935376 Common - transcriptional regulator, GntR family CLC_2712 139 COG2188 PhnF, Transcriptional regulators Transcription 153937118 Common - putative nuclease SbcCD, D subunit CLC_0546 110 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 153935338 Common - hypothetical protein CLC_3634 14 None None None 153935548 Common - hypothetical protein CLC_0559 2 None None None 153937680 Common - hypothetical protein CLC_3069 4 None None None 153937277 Common - hypothetical protein CLC_0713 29 COG2461 COG2461, Uncharacterized conserved protein Function unknown 153934674 Common - putative ATP-dependent DNA helicase PcrA CLC_0737 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153936205 Pathogen - hypothetical protein CLC_0239 1 None None None 153935331 Common - hypothetical protein CLC_0806 11 None None None 153937770 Common rplF ribosomal protein L6 CLC_3410 235 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 153935451 Pathogen - hypothetical protein CLC_2914 1 None None None 153937393 Common - ABC transporter, ATP-binding protein CLC_1918 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153934913 Common dapA dihydrodipicolinate synthase CLC_3062 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153935280 Common - exopolysaccharide biosynthesis protein CLC_3011 224 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153935306 Common rbfA ribosome-binding factor A CLC_2264 156 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 153935326 Common ftsA cell division protein FtsA CLC_2394 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 153936549 Common pgi glucose-6-phosphate isomerase CLC_3221 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 153936540 Pathogen - hypothetical protein CLC_1764 1 None None None 153936014 Common - radical SAM domain protein CLC_1928 48 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 153936057 Pathogen - hypothetical protein CLC_2566 1 None None None 153935028 Common rimM 16S rRNA processing protein RimM CLC_2294 171 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 153937838 Common xpt-1 xanthine phosphoribosyltransferase CLC_0375 84 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153935507 Common - non-haem haloperoxidase family protein CLC_0903 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153937364 Common - NADH-dependent butanol dehydrogenase CLC_1669 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 153937374 Common - hypothetical protein CLC_2247 10 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 153937155 Common - putative transcriptional regulator CLC_0914 154 COG1733 COG1733, Predicted transcriptional regulators Transcription 153937776 Common dhaD glycerol dehydrogenase CLC_1030 92 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 153936074 Common aspS-1 aspartyl-tRNA synthetase CLC_1072 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 153937458 Common dacF D-alanyl-D-alanine carboxypeptidase CLC_1802 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153936230 Common - PAP2 family protein CLC_3352 42 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 153937847 Common recN DNA repair protein recN CLC_1821 207 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 153937168 Common - oxidoreductase, FAD dependent CLC_1539 75 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153937224 Common rnc ribonuclease III CLC_2303 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 153935697 Common - putative helicase CLC_0766 73 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 153935050 Common - amino acid/peptide transporter CLC_1974 79 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 153936640 Common - CRISPR-associated protein, TM1791 family CLC_2113 4 COG1604 COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 153937789 Common - putative pleiotropic regulatory protein CLC_0889 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 153937633 Pathogen - hypothetical protein CLC_2655 1 None None None 153936506 Common - Orn/Lys/Arg decarboxylase CLC_3020 106 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 153935978 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CLC_1377 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153934713 Pathogen - hypothetical protein CLC_2098 1 None None None 153934898 Common - hypothetical protein CLC_0999 2 None None None 153937710 Common - putative electron transport protein CLC_2343 152 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 153937525 Common adk adenylate kinase CLC_3404 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 153936670 Common - oxidoreductase, NAD-binding Rossmann fold family CLC_3009 191 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153937352 Common rnz ribonuclease Z CLC_1411 108 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 153935666 Common - hypothetical protein CLC_3043 3 None None None 153937597 Common - mutS domain protein CLC_1541 196 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 153936390 Common - methyltransferase, UbiE/COQ5 family CLC_0825 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153936800 Common - spore coat protein-like protein CLC_1463 3 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 153937612 Common - Na+/H+ antiporter family protein CLC_0487 73 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 153935595 Common - hypothetical protein CLC_1795 177 COG0628 PerM, Predicted permease General function prediction only 153935971 Common trpS tryptophanyl-tRNA synthetase CLC_3276 228 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153936053 Common - hypothetical protein CLC_2747 1 None None None 153936160 Pathogen - hypothetical protein CLC_2869 1 None None None 153934877 Common xerD tyrosine recombinase XerD CLC_1808 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153934971 Common rplV ribosomal protein L22 CLC_3420 220 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 153937376 Common csrA carbon storage regulator CLC_2611 83 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 153936167 Common - NeuB family protein CLC_2594 79 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 153935059 Common - hypothetical protein CLC_0884 24 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 153937824 Common cat-1 chloramphenicol acetyltransferase CLC_0674 22 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 153936780 Common ftsK DNA translocase FtsK/SpoIIIE CLC_2254 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 153934762 Common - integral membrane protein TIGR01906 CLC_3243 9 COG4478 COG4478, Predicted membrane protein Function unknown 153936778 Common ispE 4-diphosphocytidyl-2C-methyl-D-erythritol kinase CLC_0169 195 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 153935418 Common - hypothetical protein CLC_1317 2 None None None 153936807 Common - BNR/Asp-box repeat protein CLC_1108 57 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 153935718 Common - radical SAM domain protein CLC_0258 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 153934668 Common - transcriptional regulator, LysR family CLC_0920 182 COG0583 LysR, Transcriptional regulator Transcription 153936627 Pathogen - hypothetical protein CLC_1218 1 None None None 153936480 Common - putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase CLC_0150 162 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 153937679 Common - hypothetical protein CLC_1912 17 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 153937563 Common - putative B12-binding Fe-S oxidoreductase CLC_2505 84 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 153935961 Common - hypothetical protein CLC_0248 9 None None None 153935732 Common - alanine racemase, N-terminal domain protein CLC_1949 18 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 153935848 Pathogen - hypothetical protein CLC_1173 1 None None None 153934821 Common - ABC transporter, permease protein CLC_2090 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153936956 Common - ABC transporter, permease protein CLC_3082 172 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153934627 Pathogen - hypothetical protein CLC_2438 1 None None None 153935420 Common - hypothetical protein CLC_2809 38 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 153936723 Common - phospholipase family protein CLC_0514 30 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 153936157 Common - acyl-ACP thioesterase family protein CLC_3613 23 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 153934805 Common - hypothetical protein CLC_0794 15 None None None 153936533 Common - transcriptional regulator, AraC family CLC_2658 113 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153936148 Common - HIT family protein CLC_2850 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 153937706 Common - DNA-binding protein CLC_0819 52 COG1476 COG1476, Predicted transcriptional regulators Transcription 153937161 Pathogen - hypothetical protein CLC_1995 1 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153937198 Common - hypothetical protein CLC_2612 39 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 153936935 Common - bacitracin ABC transporter, ATP-binding protein CLC_3296 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935861 Pathogen - hypothetical protein CLC_2945 1 None None None 153937434 Common fabD malonyl CoA-acyl carrier protein transacylase CLC_3579 210 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 153936179 Common - xanthine/uracil permease family protein CLC_2132 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 153935164 Common - iron compound ABC transporter, permease protein CLC_0369 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153937285 Common - hypothetical protein CLC_0913 142 COG1741 COG1741, Pirin-related protein General function prediction only 153937038 Common hup DNA-binding protein HU CLC_3512 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 153936303 Common - GTP-binding protein, EutP/PduV family CLC_2057 17 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 153935365 Common - MATE efflux family protein CLC_2657 170 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153935223 Common - hypothetical protein CLC_1987 2 None None None 153936997 Pathogen - hypothetical protein CLC_0397 1 None None None 153934564 Common - ATP-binding protein CLC_2175 154 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153934515 Common - hypothetical protein CLC_3154 2 None None None 153936916 Common - hypothetical protein CLC_0179 1 None None None 153935112 Pathogen - hypothetical protein CLC_0778 1 COG2378 COG2378, Predicted transcriptional regulator Transcription 153937539 Pathogen - hypothetical protein CLC_0997 1 None None None 153937113 Common ldhA-2 D-lactate dehydrogenase CLC_3226 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 153936333 Common - putative methylcobalamin:Coenzyme M methyltransferase CLC_1525 93 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 153935461 Common - V-type ATPase, C subunit CLC_2500 24 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 153935621 Common - MATE efflux family protein CLC_0417 140 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153936215 Common - pseudouridine synthase, RluA family CLC_2877 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 153937381 Pathogen - hypothetical protein CLC_2759 1 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 153935034 Common - amino acid/peptide transporter CLC_1707 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 153935679 Common flgK flagellar hook-associated protein FlgK CLC_2614 108 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 153935566 Common purR pur operon repressor CLC_3525 118 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153936616 Common - cation transporting ATPase-like protein CLC_1569 21 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153935427 Common - transcriptional regulator, LysR family CLC_3570 193 COG0583 LysR, Transcriptional regulator Transcription 153937136 Common - AMP-binding enzyme CLC_3235 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153935048 Common speD S-adenosylmethionine decarboxylase CLC_3308 73 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 153935493 Pathogen - hypothetical protein CLC_1282 1 None None None 153937442 Pathogen - hypothetical protein CLC_2952 1 None None None 153934557 Common - methyl-accepting chemotaxis protein CLC_0747 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153936294 Common - hypothetical protein CLC_0691 5 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 153935169 Common - lipase CLC_2005 11 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 153937694 Common purE phosphoribosylaminoimidazole carboxylase, catalytic subunit CLC_2776 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 153937664 Common psd-2 phosphatidylserine decarboxylase CLC_0042 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 153937577 Common - molecular chaperone, DnaJ family CLC_0245 225 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 153935233 Common - exonuclease family protein CLC_2214 8 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 153934609 Common - pentapeptide repeat family protein CLC_1673 10 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 153937764 Common sagI drug ABC tranporter, ATP-binding/permease protein CLC_0568 32 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 153937337 Common atpH ATP synthase F1, delta subunit CLC_0201 104 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 153935918 Common - tetratricopeptide repeat protein CLC_3380 1 None None None 153937046 Common dnaN DNA polymerase III, beta chain CLC_0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 153935465 Common accD acetyl-CoA carboxylase, carboxyl transferase, beta subunit CLC_3573 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 153935314 Common - N-acetylmuramoyl-L-alanine amidase-like protein CLC_0518 9 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 153937588 Common - hypothetical protein CLC_0060 1 None None None 153934848 Common - putative general stress protein CLC_3507 128 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 153936204 Common - hypothetical protein CLC_2411 2 None None None 153937542 Common - ATPase, AAA family CLC_3099 87 COG0714 COG0714, MoxR-like ATPases General function prediction only 153934587 Common - Ser/Thr protein phosphatase family protein CLC_0234 16 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 153935633 Pathogen - hypothetical protein CLC_3134 1 None None None 153937850 Common - electron transport complex, RnfABCDGE type, G subunit CLC_0428 72 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 153934856 Pathogen - hypothetical protein CLC_2355 1 None None None 153935915 Common - [2Fe-2S]-binding domain protein CLC_0602 2 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 153935570 Common - arsenical pump family protein CLC_0571 160 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 153937187 Common - transcriptional regulator, TetR family CLC_3553 55 COG1309 AcrR, Transcriptional regulator Transcription 153935930 Common - putative ABC transporter, substrate-binding protein CLC_0724 57 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153935610 Common - putative lipase/esterase CLC_2129 140 COG0657 Aes, Esterase/lipase Lipid metabolism 153935795 Common - MutS domain protein CLC_1932 195 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 153936781 Common gcvH glycine cleavage system H protein CLC_0751 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 153934987 Common - putative peptidyl-prolyl cis-trans isomerase, cyclophilin-type CLC_3541 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 153936468 Common clpC negative regulator of genetic competence MecB/ClpC CLC_3458 243 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 153937056 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_0419 180 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 153937398 Common cheX chemotaxis protein CheX CLC_1730 22 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 153936797 Common aspB-1 aspartate aminotransferase CLC_1746 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153936385 Common dhaKL dihydroxyacetone kinase, subunit I/II CLC_1029 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153936581 Common recQ ATP-dependent DNA helicase RecQ CLC_1048 239 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 153935116 Common - ethanolamine utilization protein EutS-like protein CLC_2058 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 153936754 Common - methyl-accepting chemotaxis protein CLC_2567 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153936178 Common - hypothetical protein CLC_1418 4 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 153937666 Common - putative lipoprotein CLC_1768 5 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153935799 Common rpmF ribosomal protein L32 CLC_2306 67 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 153936244 Common - ABC transporter, ATP-binding protein CLC_0682 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937418 Common - DNA topoisomerase, GyrA/ParC subunit family CLC_2645 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 153937430 Common - transcriptional regulator, GntR family CLC_2978 214 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153937579 Common - hypothetical protein CLC_0213 164 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153934550 Common - hypothetical protein CLC_3054 54 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 153935109 Common - ABC transporter, substrate-binding protein CLC_1197 139 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 153935285 Common - hypothetical protein CLC_1054 4 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 153937312 Common soj sporulation initiation inhibitor protein soj CLC_3638 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153937179 Common grpE co-chaperone GrpE CLC_2856 225 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 153935005 Common ldh L-lactate dehydrogenase CLC_1552 163 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 153937568 Common ftsY signal recognition particle-docking protein FtsY CLC_2299 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 153935450 Common - N-acetylmuramoyl-L-alanine amidase CLC_2746 24 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 153935694 Common hgdC-1 2-hydroxyglutaryl-CoA dehydratase component A CLC_1585 57 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 153934734 Common - hypothetical protein CLC_2222 5 None None None 153937797 Pathogen - hypothetical protein CLC_2490 1 None None None 153935755 Common pta phosphate acetyltransferase CLC_2309 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 153935167 Pathogen - hypothetical protein CLC_2924 1 None None None 153935820 Common - RNA modification enzyme, MiaB family CLC_2253 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 153937780 Common - cysteine desulfurase family protein CLC_3632 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 153936689 Common cgs cyclic beta 1-2 glucan synthetase CLC_3280 46 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 153934732 Common - putative heavy metal-binding protein CLC_1169 2 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153937870 Common - spore germination protein CLC_1921 11 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 153936993 Common plsX fatty acid/phospholipid synthesis protein PlsX CLC_2305 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 153935397 Common - hypothetical protein CLC_1797 1 None None None 153936560 Common - DNA mismatch repair protein MutL CLC_1741 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 153934598 Common gcvT glycine cleavage system T protein CLC_0750 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 153934653 Common - metallo-beta-lactamase family protein/flavodoxin CLC_2492 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 153935069 Common - hypothetical protein CLC_1182 18 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153937500 Common cfa cyclopropane-fatty-acyl-phospholipid synthase CLC_0671 136 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 153934546 Common - sulfurtransferase family protein CLC_0848 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153937262 Common fliQ flagellar biosynthesis protein FliQ CLC_2522 129 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 153936501 Common - hypothetical protein CLC_3623 9 COG4241 COG4241, Predicted membrane protein Function unknown 153935423 Common ppnK ATP-NAD kinase CLC_1823 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 153935917 Common fliC flagellin CLC_2568 107 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153936182 Common - RNA polymerase sigma-70 factor, ECF family CLC_2227 126 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153935055 Common - capsular polysaccharide biosynthsis protein CLC_2562 52 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 153935833 Common - hypothetical protein CLC_2238 2 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 153935969 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CLC_0519 179 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153937200 Common secG preprotein translocase, SecG subunit CLC_0287 5 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 153934745 Common aroH chorismate mutase CLC_1751 30 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 153935509 Pathogen - hypothetical protein CLC_0849 1 None None None 153936763 Common gap-1 glyceraldehyde-3-phosphate dehydrogenase, type I CLC_0282 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 153937333 Common - putative lipoprotein CLC_3381 1 None None None 153936923 Common - hypothetical protein CLC_2171 16 COG3326 COG3326, Predicted membrane protein Function unknown 153937724 Common - iron-sulfur cluster-binding protein CLC_2816 47 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 153936002 Common - putative lipoprotein CLC_2202 4 None None None 153935407 Common - hypothetical protein CLC_1311 2 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 153936555 Pathogen - hypothetical protein CLC_0499 1 None None None 153937122 Common - stage V sporulation protein D CLC_1493 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 153936882 Common - hypothetical protein CLC_1623 3 None None None 153937319 Common - SEC-C motif domain protein CLC_0614 44 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 153937147 Common - cytidine/deoxycytidylate deaminase family protein CLC_0311 18 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 153936340 Common motA-1 chemotaxis protein MotA CLC_2149 82 COG1291 MotA, Flagellar motor component Cell motility and secretion 153935579 Common - putative DNA-binding protein CLC_3456 30 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 153934875 Common holA DNA polymerase III, delta subunit CLC_2864 45 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 153937463 Common - kinase, pfkB family CLC_1938 98 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 153937583 Common - hypothetical protein CLC_0124 30 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 153936488 Common arcD arginine/ornithine antiporter CLC_1618 166 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153934946 Common - oxidoreductase, 2-nitropropane dioxygenase family CLC_3580 130 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 153936577 Common - transcriptional regulator, AraC family CLC_0835 59 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153935400 Pathogen - hypothetical protein CLC_2019 1 None None None 153936093 Common - V-type ATPase, E subunit CLC_2501 14 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 153935176 Common - putative sodium extrusion protein NatB CLC_2160 57 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 153936475 Pathogen - hypothetical protein CLC_0598 1 None None None 153935060 Common - cyclic nucleotide-binding domain protein CLC_1580 35 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153935204 Common - hypothetical protein CLC_2199 4 None None None 153935171 Common - pseudouridine synthase, RluA family CLC_1513 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 153934685 Common - PTS system, glucose/maltose-specific, IIA component CLC_0349 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 153937029 Pathogen - hypothetical protein CLC_0936 1 None None None 153936229 Pathogen - hypothetical protein CLC_0447 1 None None None 153936705 Common rpe ribulose-phosphate 3-epimerase CLC_2357 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 153936373 Common - sensor histidine kinase CLC_1171 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153937100 Common glmU UDP-N-acetylglucosamine pyrophosphorylase CLC_3523 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 153937690 Common - putative undecaprenyl-phosphate galactosephosphotransferase CLC_2559 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 153934801 Pathogen - hypothetical protein CLC_2675 1 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 153936363 Common - DNA-binding response regulator CLC_1024 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935883 Common acpP-2 acyl carrier protein CLC_3581 196 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153937109 Common - DNA-binding response regulator CLC_1640 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936986 Common era GTP-binding protein Era CLC_2841 233 COG1159 Era, GTPase General function prediction only 153937465 Common modB molybdate ABC transporter, permease protein CLC_1520 229 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 153934682 Common - C4-dicarboxylate transporter/malic acid transport protein CLC_1555 28 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 153936213 Common crm2 CRISPR-associated protein, Crm2 family CLC_2117 22 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 153936855 Common - transcriptional regulator, Rex family CLC_3248 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 153936824 Common - hypothetical protein CLC_1092 3 COG3462 COG3462, Predicted membrane protein Function unknown 153937128 Common - ABC transporter, permease protein CLC_1198 176 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 153935134 Common folE GTP cyclohydrolase I CLC_1588 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 153937061 Common - TraX family protein CLC_1784 10 None None None 153936125 Common - hypothetical protein CLC_2515 1 None None None 153937347 Common - electron transport complex, RnfABCDGE type, D subunit CLC_0427 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 153935605 Common - putative nonribosomal peptide synthetase CLC_2459 200 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 153936136 Common - methyl-accepting chemotaxis protein CLC_2317 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937507 Pathogen - hypothetical protein CLC_2935 1 None None None 153935745 Common - hypothetical protein CLC_2269 170 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 153935041 Pathogen - hypothetical protein CLC_1320 1 None None None 153937059 Common - transcriptional regulator, PadR family CLC_0652 15 COG1695 COG1695, Predicted transcriptional regulators Transcription 153935630 Pathogen - hypothetical protein CLC_1275 1 None None None 153934929 Common smpB SsrA-binding protein CLC_0290 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 153937303 Common - ABC transporter, ATP-binding protein CLC_3075 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153935390 Common - putative iron-dependent repressor CLC_1572 90 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 153937217 Common - precorrin-2 dehydrogenase CLC_0974 3 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 153936853 Common ribF riboflavin biosynthesis protein RibF CLC_2261 211 COG0196 RibF, FAD synthase Coenzyme metabolism 153935868 Pathogen - hypothetical protein CLC_0138 1 None None None 153936082 Pathogen - hypothetical protein CLC_1196 1 None None None 153934996 Common - hypothetical protein CLC_2320 33 COG1915 COG1915, Uncharacterized conserved protein Function unknown 153937018 Common - hypothetical protein CLC_2692 8 None None None 153937855 Common - UDP-N-acetylmuramyl tripeptide synthetase-like protein CLC_0467 49 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 153937288 Common - glycosyl transferase, group 1 family protein CLC_2578 86 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153935308 Common - flagellin CLC_0854 75 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153934672 Common - sensor histidine kinase CLC_1639 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935785 Common - hypothetical protein CLC_3342 2 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 153936368 Common rpsI ribosomal protein S9 CLC_3389 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 153935291 Common - conserved hypothetical protein TIGR00726 CLC_2387 178 COG1496 COG1496, Uncharacterized conserved protein Function unknown 153937608 Common def-1 peptide deformylase CLC_2217 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 153936908 Common - methyl-accepting chemotaxis protein CLC_2687 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153934591 Common - NADH-dependent butanol dehydrogenase CLC_1444 173 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 153934534 Pathogen - hypothetical protein CLC_1950 1 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 153935024 Common - NHL repeat protein CLC_2640 44 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153934621 Pathogen - hypothetical protein CLC_2826 1 None None None 153937395 Common - hypothetical protein CLC_0775 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153935774 Common aroE shikimate 5-dehydrogenase CLC_2398 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 153937020 Common - aconitase/isopropylmalate dehydratase family protein CLC_0484 223 COG1048 AcnA, Aconitase A Energy production and conversion 153935818 Common - glycosyl transferase, group 1 family protein CLC_1107 20 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153935624 Common - hypothetical protein CLC_0693 32 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 153936868 Common - hypothetical protein CLC_2208 2 None None None 153937749 Common - hypothetical protein CLC_2410 1 None None None 153935923 Common - methyl-accepting chemotaxis protein CLC_1947 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937723 Common - malic enzyme CLC_0304 202 COG0281 SfcA, Malic enzyme Energy production and conversion 153936787 Pathogen - hypothetical protein CLC_2232 1 None None None 153934816 Common - germination protein, Ger(x)C family CLC_0173 16 None None None 153935477 Common - peptide ABC transporter, Pep4E family, ATP-binding protein CLC_1428 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153935823 Common groL chaperonin GroEL CLC_3240 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 153936435 Common - amine oxidase, flavin-containing CLC_1239 27 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 153936570 Common - PemK family protein CLC_3339 60 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 153937238 Common - GatB/Yqey domain protein CLC_2848 148 COG1610 COG1610, Uncharacterized conserved protein Function unknown 153935722 Common - sodium:alanine symporter family protein CLC_1333 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153937354 Common - V-type ATPase, I subunit CLC_2503 49 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 153934690 Common - hypothetical protein CLC_1474 1 None None None 153935258 Common - hypothetical protein CLC_1042 1 None None None 153937339 Common - NlpC/P60 family protein CLC_0578 159 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 153936355 Common - ethanolamine utilization protein EutQ-like protein CLC_2052 16 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 153935555 Common - ABC transporter, ATP-binding/permease protein CLC_0372 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153935239 Common - HAD hydrolase, IIB family CLC_3275 142 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 153935896 Common sigF RNA polymerase sigma-F factor CLC_2989 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 153936653 Common - major facilitator family transporter CLC_1642 132 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 153937558 Common - 2-hydroxychromene-2-carboxylate isomerase family protein CLC_0344 68 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 153934525 Common clpP-2 ATP-dependent Clp protease, proteolytic subunit ClpP CLC_3142 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153936169 Common gpmI 2,3-bisphosphoglycerate-independent phosphoglycerate mutase CLC_0285 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 153935076 Common - putative cytochrome c-type biogenesis protein CLC_1761 44 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153934791 Pathogen - hypothetical protein CLC_1128 1 None None None 153936040 Common - antibiotic ABC transporter, ATP-binding protein CLC_1612 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937653 Common sodF Mn/Fe superoxide dismutase CLC_2204 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 153936975 Common - EAL domain protein CLC_0522 48 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 153935842 Common - putative phosphatase CLC_2170 114 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 153936682 Common - putative polyhedral organelle formation protein CLC_2053 37 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 153935521 Common - putative chemotaxis protein CheW CLC_2619 80 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 153937005 Common - putative membrane-associated zinc metalloprotease CLC_2272 219 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 153934543 Common gcpE 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CLC_2271 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 153937370 Common - putative D-proline reductase, PrdB subunit, selenocysteine-containing CLC_2311 13 None None None 153937050 Common - hypothetical protein CLC_3345 2 None None None 153937454 Common - hypothetical protein CLC_2338 6 None None None 153936035 Common - 67 kDa myosin-cross-reactive antigen family protein CLC_1989 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 153937656 Common lspA signal peptidase II CLC_1512 188 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153936965 Common - putative transporter CLC_1192 149 COG0628 PerM, Predicted permease General function prediction only 153935730 Pathogen - hypothetical protein CLC_0683 1 None None None 153935434 Common - transcriptional regulator, MerR family/methyltransferase, UbiE/COQ5 family CLC_0887 135 COG0789 SoxR, Predicted transcriptional regulators Transcription 153935808 Common - exopolysaccharide biosynthesis protein CLC_2561 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 153934756 Common - glycoprotease family protein CLC_3266 171 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 153936875 Common - kinase, PfkB family CLC_1712 132 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153937684 Common murI glutamate racemase CLC_3542 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 153936402 Pathogen - hypothetical protein CLC_1968 1 None None None 153936444 Common - sortase family protein CLC_2076 41 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 153935928 Pathogen - hypothetical protein CLC_2034 1 None None None 153935779 Pathogen - hypothetical protein CLC_2405 1 None None None 153936267 Common gluD glutamate dehydrogenase, NAD-specific CLC_1753 176 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 153937802 Pathogen - hypothetical protein CLC_1711 1 None None None 153934501 Common - lrgA family protein CLC_0382 67 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 153937478 Pathogen - hypothetical protein CLC_2802 1 None None None 153936601 Common - hypothetical protein CLC_2570 7 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 153936532 Common - putative 8-oxoguanine DNA glycosylase CLC_3245 25 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 153936588 Pathogen - hypothetical protein CLC_0954 1 None None None 153937863 Common - CAAX amino terminal protease family protein CLC_0657 20 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 153937035 Common - putative anion ABC transporter, permease protein CLC_1018 215 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 153935157 Common - amidohydrolase family protein CLC_1468 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153937382 Common lepA GTP-binding protein LepA CLC_2859 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 153934826 Pathogen - hypothetical protein CLC_2423 1 None None None 153937244 Pathogen - hypothetical protein CLC_2213 1 None None None 153936631 Common - hypothetical protein CLC_1894 23 COG0398 COG0398, Uncharacterized conserved protein Function unknown 153935152 Common yqfC sporulation protein YqfC CLC_2847 15 None None None 153937495 Common - electron transfer flavoprotein, beta subunit/FixA family protein CLC_1060 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 153936103 Common - exsB protein CLC_1589 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 153934496 Common - hypothetical protein CLC_0181 1 None None None 153937599 Common - cation efflux family protein CLC_1570 200 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 153936816 Common - PHP domain protein CLC_3322 49 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 153937628 Common - hypothetical protein CLC_2316 11 None None None 153935316 Pathogen - hypothetical protein CLC_0495 2 None None None 153936611 Common - putative sensory box-containing diguanylate cyclase CLC_1557 193 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 153935304 Common - cell division protein FtsQ CLC_1498 19 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 153934707 Common - iron-sulfur cluster-binding protein CLC_0932 21 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 153937510 Common - hypothetical protein CLC_0718 3 None None None 153934836 Common - hypothetical protein CLC_1701 11 COG4086 COG4086, Predicted secreted protein Function unknown 153937253 Common serS-1 seryl-tRNA synthetase CLC_0024 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 153934932 Common - xanthine/uracil permease family protein CLC_0374 130 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 153935954 Common - peptide/opine/nickel uptake ABC transporter, PepT family, permease protein CLC_1698 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153934628 Common - putative 1-acyl-sn-glycerol-3-phosphate acyltransferase CLC_0482 201 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 153935467 Common - aminotransferase, classes I and II CLC_3064 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153936494 Pathogen - hypothetical protein CLC_2336 1 None None None 153935007 Common - hypothetical protein CLC_2190 2 None None None 153934758 Common - hypothetical protein CLC_3313 4 None None None 153937172 Common pyrE orotate phosphoribosyltransferase CLC_3146 130 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 153935644 Common - formate acetyltransferase CLC_3093 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 153935801 Common - hypothetical protein CLC_1278 1 None None None 153936285 Common typA GTP-binding protein TypA CLC_2429 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 153935996 Common - hypothetical protein CLC_1354 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 153936027 Common atpB ATP synthase F0, A subunit CLC_0198 149 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 153937444 Pathogen - hypothetical protein CLC_2650 1 None None None 153934950 Common - hypothetical protein CLC_3222 14 None None None 153937263 Common - metallo-beta-lactamase family protein CLC_3546 57 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 153935212 Common - oxidoreductase, aldo/keto reductase family CLC_1542 191 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 153937807 Common - peptidase, U32 family CLC_3026 143 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 153937011 Common - metallopeptidase, family M24 CLC_2188 186 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153937614 Common - universal stress protein family protein CLC_2682 5 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 153935677 Common - ABC transporter, ATP-binding protein CLC_1161 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153935453 Common - major facilitator superfamily protein CLC_1374 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153937451 Common - phenazine biosynthesis protein, PhzF family CLC_0901 66 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 153937769 Common priA primosomal protein N' CLC_2366 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 153937226 Common - DNA-binding response regulator, LytTr family CLC_0632 104 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 153935271 Common - DNA-cytosine methyltransferase family protein CLC_0945 112 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 153935541 Pathogen - hypothetical protein CLC_2921 1 None None None 153935991 Common - glycerophosphoryl diester phosphodiesterase family protein CLC_2822 185 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 153937836 Common - carbohydrate binding protein CLC_1903 18 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 153936547 Common purM phosphoribosylformylglycinamidine cyclo-ligase CLC_2773 233 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 153935816 Common - polar amino acid uptake family ABC transporter, PAAT family, ATP-binding protein CLC_1962 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153937025 Common - hypothetical protein CLC_1385 21 None None None 153936638 Common dnaG DNA primase CLC_2834 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 153935052 Common mreC rod shape-determining protein MreC CLC_2898 158 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 153936278 Common - methyl-accepting chemotaxis protein CLC_1559 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153935324 Common - PTS system, glucitol/sorbitol-specific, IIA component CLC_3359 22 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 153937537 Common folP dihydropteroate synthase CLC_0883 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 153934793 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CLC_1721 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153935699 Common - hypothetical protein CLC_3028 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 153934907 Common murG undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase CLC_2635 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 153937488 Common - aminopeptidase II CLC_2670 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 153936191 Common - antibiotic ABC transporter, ATP-binding protein CLC_0038 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935500 Common - site-specific recombinase, phage integrase family CLC_2757 116 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153934892 Common - ADP-ribosylglycohydrolase family protein CLC_1794 75 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 153936672 Common - putative RNA polymerase-binding protein DksA CLC_1511 145 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 153936802 Common - tetratricopeptide repeat protein CLC_0442 4 None None None 153935688 Common nadC nicotinate-nucleotide pyrophosphorylase CLC_1484 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 153936328 Pathogen - hypothetical protein CLC_2549 1 None None None 153936287 Common - hypothetical protein CLC_1384 15 COG3554 COG3554, Uncharacterized protein conserved in bacteria Function unknown 153936944 Common kdgT 2-keto-3-deoxygluconate transporter CLC_0305 27 COG2855 COG2855, Predicted membrane protein Function unknown 153936392 Common - hypothetical protein CLC_0653 3 None None None 153935219 Common iscS-1 cysteine desulfhydrase CLC_1225 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 153935363 Common - flagellar protein FliJ CLC_2533 3 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 153936012 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CLC_0361 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153936482 Common addB ATP-dependent nuclease subunit B CLC_0492 36 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 153935443 Common - isochorismate family protein CLC_0316 36 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153934711 Common dinB DNA polymerase IV CLC_2694 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 153936792 Common metK S-adenosylmethionine synthetase CLC_0222 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 153936055 Common ilvD dihydroxy-acid dehydratase CLC_0350 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 153936164 Common - transcriptional regulator, AraC family CLC_0678 107 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153935357 Common rnhB ribonuclease HII CLC_2289 201 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 153935095 Common - hypothetical protein CLC_1106 2 None None None 153936412 Common npr-3 thermolysin metallopeptidase CLC_1480 47 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 153934930 Pathogen - hypothetical protein CLC_0795 1 None None None 153936511 Common modA molybdate ABC transporter, periplasmic molybdate-binding protein CLC_1519 163 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 153935196 Common secD protein-export membrane protein SecD CLC_2965 217 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 153935879 Common - hypothetical protein CLC_0626 1 None None None 153935245 Pathogen - hypothetical protein CLC_0592 1 None None None 153934768 Common - ribonuclease, Rne/Rng family CLC_2887 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 153934531 Common - hypothetical protein CLC_0433 23 COG4769 COG4769, Predicted membrane protein Function unknown 153936047 Common - hypothetical protein CLC_1967 13 COG3478 COG3478, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 153934760 Common - vanW family protein CLC_0875 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 153937258 Common - metalloendopeptidase, putative, glycoprotease family CLC_3255 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 153935943 Pathogen - hypothetical protein CLC_2150 1 None None None 153935657 Common - DNA-binding response regulator CLC_0665 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935373 Common - DNA binding protein, excisionase family CLC_2754 3 None None None 153934631 Common - RNA-metabolising metallo-beta-lactamase CLC_1332 163 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 153937590 Common ftsH-2 ATP-dependent metalloprotease FtsH CLC_3488 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 153936704 Common - hypothetical protein CLC_2022 11 None None None 153935486 Common - ABC transporter, ATP-binding protein CLC_2091 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153934667 Common - hypothetical protein CLC_0188 1 None None None 153935229 Common - GTP-binding protein CLC_3138 185 COG0218 COG0218, Predicted GTPase General function prediction only 153935642 Common - putative CoA-substrate-specific enzyme activase CLC_3105 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 153936679 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_0236 248 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 153934854 Common - ABC transporter transcriptional regulator, MerR family CLC_1900 32 COG0789 SoxR, Predicted transcriptional regulators Transcription 153936038 Common - iron-sulfur cluster-binding protein CLC_0019 47 COG2006 COG2006, Uncharacterized conserved protein Function unknown 153935084 Common thrS threonyl-tRNA synthetase CLC_3041 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937144 Common - hypothetical protein CLC_2903 1 None None None 153934709 Common - hypothetical protein CLC_0241 81 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153935875 Common - conserved hypothetical protein TIGR00255 CLC_2371 139 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 153936688 Common - flagellar basal body rod protein CLC_2513 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 153936227 Common - putative peptide deformylase CLC_0929 189 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 153937840 Common - hypothetical protein CLC_0699 5 COG1478 COG1478, Uncharacterized conserved protein Function unknown 153937819 Common - cation-transporting ATPase, P-type CLC_1344 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153936877 Common - ABC transporter, ATP-binding protein/permease protein CLC_1345 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153935349 Common nrdD anaerobic ribonucleoside-triphosphate reductase CLC_0141 106 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 153935564 Pathogen - hypothetical protein CLC_1978 1 None None None 153936918 Common - hypothetical protein CLC_0797 1 None None None 153936776 Common - manganese/zinc/iron chelate uptake ABC transporter, Mzt family, substrate-binding protein CLC_1399 174 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 153934868 Common - putative oligopeptide ABC transporter, oligopeptide-binding protein CLC_1268 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153935230 Common - methyl-accepting chemotaxis protein CLC_1390 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153935546 Common - hypothetical protein CLC_1846 1 None None None 153936525 Common - iron-sulfur cluster-binding protein CLC_0136 9 COG1141 Fer, Ferredoxin Energy production and conversion 153937299 Common guaB inosine-5'-monophosphate dehydrogenase CLC_3238 243 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 153936848 Common - PRC-barrel domain protein CLC_2437 1 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 153934479 Common nusB N utilization substance protein B CLC_1830 156 COG0781 NusB, Transcription termination factor Transcription 153935149 Common - hypothetical protein CLC_3320 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 153936809 Common - hypothetical protein CLC_0340 1 None None None 153934511 Common accB acetyl-CoA carboxylase, biotin carboxyl carrier protein CLC_3576 184 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 153934781 Common - RelA/SpoT domain protein CLC_1625 32 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 153934915 Common - bacterial transferase, hexapeptide repeat family CLC_0454 213 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 153936661 Common pyrC dihydroorotase, multifunctional complex type CLC_3150 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 153936114 Common hemC porphobilinogen deaminase CLC_0975 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 153937291 Common - transcriptional regulator, MarR family CLC_3583 51 COG1846 MarR, Transcriptional regulators Transcription 153936253 Common - hypothetical protein CLC_0925 5 None None None 153936346 Pathogen - hypothetical protein CLC_1083 1 None None None 153935635 Common - CBS domain protein CLC_1127 114 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 153937157 Common - Mg chelatase-like protein CLC_2287 197 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 153936462 Common - hypothetical protein CLC_0809 16 None None None 153936011 Common - NAD-dependent epimerase/dehydratase family protein CLC_2598 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153935889 Pathogen - CAAX amino terminal protease family protein CLC_0564 2 None None None 153936713 Common - putative R-2-hydroxyglutaryl-CoA dehydratase, alpha subunit CLC_2141 12 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153936668 Common rpoA DNA-directed RNA polymerase, alpha subunit CLC_3396 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 153936949 Common - radical SAM protein, TIGR01212 family CLC_3534 83 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 153936643 Common feoB-2 ferrous iron transport protein B CLC_1082 178 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 153934691 Common - dihydroorotate dehydrogenase family protein CLC_2695 156 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 153937766 Common - putative thymidylate kinase CLC_0102 23 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 153937067 Pathogen - hypothetical protein CLC_0510 1 None None None 153937096 Common - MazG family protein CLC_1193 16 COG1694 MazG, Predicted pyrophosphatase General function prediction only 153937794 Common fliN flagellar motor switch protein FliN CLC_2617 124 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 153936202 Common - hypothetical protein CLC_2915 2 None None None 153935125 Common fliH flagellar assembly protein FliH CLC_2535 9 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 153937530 Common adhE aldehyde-alcohol dehydrogenase CLC_0403 206 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 153936296 Common - hypothetical protein CLC_3205 1 None None None 153935019 Common - putative CoA-substrate-specific enzyme activase CLC_3080 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 153937696 Common - DNA-cytosine methyltransferase family protein CLC_2229 112 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 153935185 Common - DNA-binding response regulator CLC_0323 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937565 Common - hypothetical protein CLC_1705 20 COG1309 AcrR, Transcriptional regulator Transcription 153936926 Common - acetyltransferase, GNAT family CLC_0910 7 COG0456 RimI, Acetyltransferases General function prediction only 153935603 Common - hypothetical protein CLC_0667 15 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 153935032 Common rplS ribosomal protein L19 CLC_2292 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 153935140 Common cobA/hemD uroporphyrinogen III synthase/methyltransferase CLC_0976 207 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 153935932 Common - hypothetical protein CLC_1144 51 COG1284 COG1284, Uncharacterized conserved protein Function unknown 153937359 Common gidA-1 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CLC_2241 6 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153935986 Common nrdR transcriptional regulator, NrdR family CLC_2388 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 153937086 Common - putative antibiotic transporter response regulator CLC_1615 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937048 Common - radical SAM enzyme, Cfr family CLC_2361 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 153935198 Common - hypothetical protein CLC_2868 23 None None None 153936338 Common - putative iron chelate uptake ABC transporter, solute-binding protein CLC_2794 74 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153937603 Pathogen - hypothetical protein CLC_2403 1 None None None 153934596 Common - putative asparagine synthetase, glutamine-hydrolyzing CLC_2579 93 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 153935866 Common - putative DNA polymerase III, delta prime subunit CLC_0104 233 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 153936382 Common - hypothetical protein CLC_2789 25 None None None 153937189 Pathogen - hypothetical protein CLC_2072 1 None None None 153935416 Common - transcriptional regulator, AsnC family CLC_0450 119 COG1522 Lrp, Transcriptional regulators Transcription 153934924 Common - hypothetical protein CLC_2035 11 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 153934559 Common - bacterial type II secretion system protein F CLC_1852 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 153934774 Common - amidase domain protein CLC_0432 6 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 153936212 Common - hypothetical protein CLC_2725 46 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 153935162 Common fliF flagellar M-ring protein fliF CLC_2537 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 153934552 Common - sensor histidine kinase CLC_1432 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153937274 Common hpt-2 hypoxanthine phosphoribosyltransferase CLC_3489 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 153935531 Common - transcriptional regulator, RpiR family CLC_1754 91 COG1737 RpiR, Transcriptional regulators Transcription 153935664 Common - transcriptional regulator, GntR family/aminotransferase CLC_0692 193 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153936305 Pathogen - hypothetical protein CLC_1785 1 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 153935627 Common - peptide ABC transporter, Pep4E family, permease protein CLC_0380 22 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153935952 Common potB spermidine/putrescine ABC transporter, permease protein PotB CLC_0619 214 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153937843 Common - oxidoreductase, short chain dehydrogenase/reductase family CLC_1689 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153937449 Common - DNA-binding protein CLC_0658 28 COG1476 COG1476, Predicted transcriptional regulators Transcription 153934974 Common hgdC-2 2-hydroxyglutaryl-CoA dehydratase component A CLC_2135 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 153934645 Common - hypothetical protein CLC_2546 1 None None None 153935086 Pathogen - hypothetical protein CLC_1286 1 None None None 153936176 Common - putative DNA-binding protein CLC_0600 60 COG1476 COG1476, Predicted transcriptional regulators Transcription 153936594 Common - sensor histidine kinase CLC_1913 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936535 Pathogen - hypothetical protein CLC_1677 2 COG3422 COG3422, Uncharacterized conserved protein Function unknown 153937713 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CLC_1276 135 COG0756 Dut, dUTPase Nucleotide transport and metabolism 153937196 Common pstA phosphate ABC transporter, permease protein PstA CLC_2382 228 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 153935225 Common - transcriptional regulator, GntR family/aminotransferase, classes I and II CLC_2126 218 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153936596 Common - putative PRD domain protein/PTS system, L-ascorbate family, IIA component CLC_2093 56 COG3711 BglG, Transcriptional antiterminator Transcription 153937340 Common ddlB D-alanine--D-alanine ligase CLC_0526 216 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 153936721 Pathogen - hypothetical protein CLC_0966 1 None None None 153935344 Common - methionine ABC transporter, MUT family, permease protein CLC_1534 154 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 153935328 Common nadE glutamine-dependent NAD(+) synthetase CLC_0461 187 COG0171 NadE, NAD synthase Coenzyme metabolism 153935959 Common - putative magnesium and cobalt transport protein CorA CLC_2478 179 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 153936933 Common - hypothetical protein CLC_3024 55 COG1683 COG1683, Uncharacterized conserved protein Function unknown 153935114 Common - xanthine dehydrogenase family protein, FAD-binding subunit CLC_2727 53 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 153935852 Common - cellulose synthase domain protein CLC_1337 22 None None None 153934613 Common - hypothetical protein CLC_3101 33 COG1915 COG1915, Uncharacterized conserved protein Function unknown 153936232 Common - [Fe] hydrogenase CLC_3530 31 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 153937163 Common - sporulation domain protein CLC_1773 15 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 153937570 Common - hypothetical protein CLC_0443 1 None None None 153937182 Common fba fructose-1,6-bisphosphate aldolase, class II CLC_0249 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 153937134 Common - glycosyl transferase-like protein CLC_2572 30 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 153936499 Common fhuB ferrichrome ABC transporter, permease protein FhuB CLC_0741 168 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153935429 Common - PTS system, beta-glucoside-specific, IIABC component CLC_0708 57 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153935841 Common - pyridoxamine 5'-phosphate oxidase family protein CLC_0690 27 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 153937349 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_1793 11 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 153935593 Common - CoA-transferase, B subunit CLC_2724 101 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 153935180 Common rpoN RNA polymerase sigma-54 factor CLC_0280 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 153936832 Common - DNA-binding response regulator CLC_0423 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153934887 Common - putative ABC transporter, ATP-binding/permease protein CLC_2206 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153937549 Common - decarboxylase family protein CLC_2824 116 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 153935880 Common - transcriptional regulator, AraC family CLC_1101 115 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153936063 Common - acetyltransferase, GNAT family CLC_1747 1 COG0456 RimI, Acetyltransferases General function prediction only 153936237 Common tyrS-1 tyrosyl-tRNA synthetase CLC_1246 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937426 Common - hypothetical protein CLC_2370 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 153934513 Pathogen - hypothetical protein CLC_3291 1 None None None 153935491 Common - low molecular weight protein tyrosine phosphatase CLC_0191 33 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 153937074 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase CLC_1495 213 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 153936335 Pathogen - hypothetical protein CLC_0720 1 None None None 153935370 Common - cell wall hydrolase family protein CLC_3376 19 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 153936973 Pathogen - hypothetical protein CLC_1759 1 None None None 153935361 Common - transcriptional regulator, Fur family CLC_1407 63 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153937052 Common cphB cyanophycinase CLC_0167 33 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 153937435 Common - transcriptional regulator, TetR family CLC_0675 37 COG1309 AcrR, Transcriptional regulator Transcription 153936108 Common - D-alanyl-D-alanine carboxypeptidase family protein CLC_2876 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153937475 Common - hypothetical protein CLC_2980 6 None None None 153936081 Common xseA exodeoxyribonuclease VII, large subunit CLC_1829 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 153935652 Pathogen - hypothetical protein CLC_2929 1 None None None 153934580 Pathogen - hypothetical protein CLC_2511 1 None None None 153936755 Common oxdD oxalate decarboxylase CLC_0917 15 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 153936139 Common - aminotransferase, classes I and II CLC_1744 232 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153934880 Common - sodium:alanine symporter family protein CLC_2449 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153935582 Common - putative methionine-S-sulfoxide reductase CLC_1427 166 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 153934694 Common - hypothetical protein CLC_3145 1 None None None 153937425 Common - hypothetical protein CLC_0416 12 None None None 153934922 Common - RNA polymerase sigma-70 factor family CLC_0079 39 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153934600 Common fliD Flagellar hook-associated protein 2 CLC_2607 32 COG1345 FliD, Flagellar capping protein Cell motility and secretion 153937289 Common gcvPB glycine cleavage system P protein, subunit 2 CLC_0753 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 153934687 Common yabP sporulation protein YabP CLC_3510 14 None None None 153935385 Pathogen - hypothetical protein CLC_1714 1 None None None 153934823 Common rplX ribosomal protein L24 CLC_3414 210 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 153937658 Common - putative sporulation protein CLC_1810 15 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 153937540 Common flgD flagellar hook capping protein CLC_2531 59 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 153934623 Common - conserved hypothetical protein TIGR00252 CLC_2288 145 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 153937388 Common - peptide ABC transporter, Pep4E family, ATP-binding protein CLC_0333 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153935850 Common - SIS domain protein CLC_0339 51 COG1737 RpiR, Transcriptional regulators Transcription 153936607 Pathogen - hypothetical protein CLC_3257 1 None None None 153934728 Pathogen - acyl carrier protein-like protein CLC_2455 1 None None None 153934838 Pathogen - hypothetical protein CLC_0366 1 None None None 153934507 Pathogen - hypothetical protein CLC_0850 1 None None None 153934666 Common - putative stage IV sporulation protein CLC_2846 15 None None None 153935724 Common - putative glucitol operon regulator CLC_3364 69 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153936862 Common - extracellular exochitinase CLC_1109 24 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 153935810 Common - hypothetical protein CLC_2602 24 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 153936613 Common - acetyltransferase, GNAT family CLC_2162 93 COG2153 ElaA, Predicted acyltransferase General function prediction only 153936735 Common - apbE family protein CLC_0435 133 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 153936420 Common - ThiH/BioB family protein CLC_3561 59 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 153937572 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase / ribosomal protein S1-like protein CLC_1749 222 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 153937170 Common - hypothetical protein CLC_2820 43 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 153936065 Common - hypothetical protein CLC_0866 11 None None None 153937033 Common rsgA ribosome small subunit-dependent GTPase A CLC_2358 165 COG1162 COG1162, Predicted GTPases General function prediction only 153937249 Common - metallo-beta-lactamase family protein CLC_2216 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 153935021 Common noxA nitrate reductase, NADH oxidase subunit CLC_1371 236 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 153935389 Common tipA transcriptional activator TipA CLC_0965 90 COG0789 SoxR, Predicted transcriptional regulators Transcription 153937830 Pathogen - hypothetical protein CLC_1456 1 None None None 153936404 Pathogen - putative ATP synthase protein I CLC_0197 1 None None None 153934480 Common - acetyltransferase, GNAT family CLC_0986 23 COG0456 RimI, Acetyltransferases General function prediction only 153934586 Common - glutamyl aminopeptidase family protein CLC_0269 85 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 153934659 Common ileS isoleucyl-tRNA synthetase CLC_0147 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153935155 Pathogen - hypothetical protein CLC_0297 1 None None None 153936451 Common - nucleotidyltransferase domain protein CLC_2979 2 None None None 153935446 Common - hypothetical protein CLC_2974 3 None None None 153935277 Common secY preprotein translocase, SecY subunit CLC_3405 216 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 153937145 Common moaC molybdenum cofactor biosynthesis protein C CLC_1884 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 153937746 Common - dehydrogenase, isocitrate/isopropylmalate family CLC_0485 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 153937220 Common - hypothetical protein CLC_3527 1 None None None 153936957 Pathogen - hypothetical protein CLC_2919 1 None None None 153936316 Common - response regulator CLC_0668 212 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 153937793 Common - transcriptional regulator, Crp/Fnr family CLC_0710 183 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153936437 Common - ABC transporter, ATP-binding protein CLC_1416 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153934670 Common - methionine ABC transporter, MUT family, ATP-binding protein CLC_1533 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 153936651 Common - V-type ATPase, A subunit CLC_2498 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 153934747 Common - putative molybdate ABC transporter, ATP-binding protein CLC_1521 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153934748 Common - heme/steroid binding domain protein CLC_1780 7 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 153936662 Common - transcriptional regulator, MarR family CLC_2186 40 COG1846 MarR, Transcriptional regulators Transcription 153937177 Common - putative sugar-binding protein CLC_0155 35 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153937721 Common - hypothetical protein CLC_1473 2 COG1633 COG1633, Uncharacterized conserved protein Function unknown 153934810 Common - glycyl-radical enzyme activating family protein CLC_3094 94 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 153937730 Common - putative sigma-54 dependent transcriptional regulator CLC_1956 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153935127 Common spoIIGA sporulation factor SpoIIGA CLC_2392 11 None None None 153934771 Common - methyl-accepting chemotaxis protein CLC_0774 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153936899 Common nifH nitrogenase iron protein CLC_0744 72 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 153934498 Common - N-acetylmuramoyl-L-alanine amidase CLC_0799 23 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 153936008 Common - putative ABC transporter, ATP-binding/permease protein CLC_1877 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153934649 Common fldA E-cinnamoyl-CoA:R-phenyllactate CoA transferase CLC_3234 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 153937363 Common - methyl-accepting chemotaxis protein CLC_1590 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937857 Pathogen - hypothetical protein CLC_2164 1 None None None 153937573 Pathogen - hypothetical protein CLC_2703 1 None None None 153935589 Common - methyl-accepting chemotaxis protein CLC_1686 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937626 Pathogen - hypothetical protein CLC_2737 1 None None None 153936812 Common - putative electron transport protein CLC_2335 113 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 153935963 Common - GGDEF/HD domain protein CLC_0391 178 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 153937518 Common - hypothetical protein CLC_2267 44 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 153937605 Common - hypothetical protein CLC_1194 6 None None None 153936284 Common greA-1 transcription elongation factor GreA CLC_0730 180 COG0782 GreA, Transcription elongation factor Transcription 153935142 Common - YbaK/prolyl-tRNA synthetase domain protein CLC_1718 115 COG2606 EbsC, Uncharacterized conserved protein Function unknown 153935211 Common - hypothetical protein CLC_0448 5 None None None 153935616 Common rpsE ribosomal protein S5 CLC_3408 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 153935733 Pathogen - hypothetical protein CLC_0719 1 None None None 153937323 Common - methyl-accepting chemotaxis protein CLC_0609 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153935925 Pathogen - small acid-soluble spore protein, H-type CLC_0845 1 None None None 153936456 Pathogen - hypothetical protein CLC_0545 1 None None None 153934491 Common - polysaccharide biosynthesis protein CLC_2551 11 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153934469 Common - major facilitator family protein CLC_3551 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153936630 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha region CLC_3386 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 153936659 Pathogen - hypothetical protein CLC_1862 1 None None None 153934842 Common - oxidoreductase, FAD/[2Fe-2S]-binding CLC_2167 162 COG0579 COG0579, Predicted dehydrogenase General function prediction only 153934818 Common argF ornithine carbamoyltransferase CLC_2465 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 153935275 Common - DNA-binding response regulator CLC_1866 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937150 Pathogen - hypothetical protein CLC_2674 1 None None None 153937689 Pathogen - hypothetical protein CLC_2916 1 None None None 153937728 Common - putative methylcobalamin:Coenzyme M methyltransferase CLC_1529 9 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 153935769 Common - hypothetical protein CLC_1250 3 None None None 153936228 Pathogen - hypothetical protein CLC_0039 1 None None None 153935764 Common - transporter, HlyC/CorC family CLC_2805 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 153937080 Common - hypothetical protein CLC_1724 2 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 153935831 Common - methyltransferase-like protein CLC_2590 50 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 153937485 Common - NAD-dependent epimerase/dehydratase family protein CLC_2588 227 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153936495 Pathogen - hypothetical protein CLC_3635 1 None None None 153936504 Common - putative diamine N-acetyltransferase CLC_1217 16 COG0456 RimI, Acetyltransferases General function prediction only 153936246 Common lexA LexA repressor CLC_1737 175 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 153936134 Common - hypothetical protein CLC_2606 1 None None None 153934957 Common - GTP-binding protein CLC_3562 198 COG1160 COG1160, Predicted GTPases General function prediction only 153936821 Common - hypothetical protein CLC_1465 120 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153935202 Common - parB family protein CLC_3639 189 COG1475 Spo0J, Predicted transcriptional regulators Transcription 153936429 Common fusA-2 translation elongation factor G CLC_3463 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 153936486 Common - PAP2 family protein CLC_0408 140 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 153935079 Common - hypothetical protein CLC_1041 4 None None None 153937866 Common - transcriptional regulator, AraC family CLC_0621 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153936623 Common - hypothetical protein CLC_2832 1 None None None 153935371 Common bofA sigma-K factor processing regulatory protein BofA CLC_0055 11 None None None 153937468 Common - flavodoxin-like fold domain protein CLC_0906 78 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 153934650 Common infC translation initiation factor IF-3 CLC_3040 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 153936476 Common - hypothetical protein CLC_0232 11 None None None 153935177 Common asnS asparaginyl-tRNA synthetase CLC_0651 239 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 153935740 Common - transcriptional regulator, Crp/Fnr family CLC_1373 164 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153936362 Common - hypothetical protein CLC_1453 3 None None None 153935070 Common - response regulator CLC_0583 218 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 153937206 Common - conserved hypothetical protein TIGR00147 CLC_0256 117 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 153936152 Common - hypothetical protein CLC_3067 2 None None None 153936343 Common - hypothetical protein CLC_2092 2 None None None 153935472 Pathogen - hypothetical protein CLC_0851 1 None None None 153934548 Pathogen - hypothetical protein CLC_0560 1 None None None 153935904 Common - stage V sporulation protein AD family protein CLC_2987 15 None None None 153935748 Common - ABC transporter, permease protein CLC_2008 3 None None None 153936575 Common tagO UDP-GlcNAc:undecaprenyl-P GlcNAc 1-P transferase CLC_0195 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 153935003 Common pilT twitching motility protein CLC_2397 209 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 153936089 Pathogen - hypothetical protein CLC_1910 1 None None None 153935150 Common - dinitrogenase iron-molybdenum cofactor biosynthesis CLC_2143 31 COG1433 COG1433, Uncharacterized conserved protein Function unknown 153936095 Common - hypothetical protein CLC_2691 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 153937315 Pathogen - hypothetical protein CLC_0604 1 None None None 153937215 Common - bacitracin ABC transporter, ATP-binding protein CLC_0833 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935439 Common alr-1 alanine racemase CLC_0335 201 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 153935100 Common - hypothetical protein CLC_1020 10 COG2014 COG2014, Uncharacterized conserved protein Function unknown 153935435 Common - hypothetical protein CLC_0554 1 None None None 153934740 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 CLC_2631 64 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 153937874 Common - putative DNA-binding protein CLC_2422 7 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 153935647 Common - hypothetical protein CLC_0273 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 153937582 Common - hypothetical protein CLC_0767 40 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 153937098 Common - acyl-CoA dehydrogenase family protein/electron transfer protein CLC_2719 207 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153934804 Common nrdG anaerobic ribonucleoside-triphosphate reductase activating protein CLC_0142 71 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 153934949 Common - hypothetical protein CLC_1731 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 153936568 Common - polar amino acid uptake ABC transporter, PAAT family, amino acid-binding protein CLC_1448 166 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153936851 Common - hypothetical protein CLC_2420 5 None None None 153935022 Common - PTS system, glucose family, IIABC component CLC_2628 59 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153937861 Common - NAD-dependent glycerol-3-phosphate dehydrogenase family protein CLC_2377 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153937068 Common thiD-2 phosphomethylpyrimidine kinase CLC_0827 223 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 153934551 Common - hypothetical protein CLC_3484 2 None None None 153935685 Common aroF phospho-2-dehydro-3-deoxyheptonate aldolase CLC_1509 189 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 153937032 Common ptsG PTS system, glucose-specific, IIABC component CLC_1364 61 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153935442 Common - hypothetical protein CLC_0955 7 None None None 153935859 Common purD phosphoribosylamine--glycine ligase CLC_2770 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 153937103 Common - hypothetical protein CLC_1452 4 None None None 153935062 Common - YihY family protein CLC_3348 172 COG1295 Rbn, Predicted membrane protein Function unknown 153936037 Common thrC threonine synthase CLC_1664 131 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 153935251 Common gerAC spore germination protein CLC_2671 9 None None None 153936941 Pathogen - hypothetical protein CLC_2341 1 None None None 153936836 Common - putative cobalt ABC transporter, ATP-binding protein CLC_3393 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 153936414 Common - putative 6-pyruvoyl tetrahydropterin synthase CLC_1586 91 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 153936625 Common - iron-sulfur cluster-binding protein CLC_2683 24 COG0348 NapH, Polyferredoxin Energy production and conversion 153935753 Common - phosphodiesterase, MJ0936 family CLC_1050 49 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153936231 Common - V-type ATPase, G subunit CLC_2499 10 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 153935713 Common flhF flagellar biosynthesis protein FlhF CLC_2519 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 153936971 Common - peptidase, M20/M25/M40 family CLC_2477 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 153936991 Common - hypothetical protein CLC_1561 3 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 153937523 Common - glycosyl transferase, WecB/TagA/CpsF family CLC_2994 110 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 153937506 Common - hypothetical protein CLC_1249 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 153935303 Common recF DNA replication and repair protein RecF CLC_0004 152 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 153936389 Common - hypothetical protein CLC_2124 45 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153937782 Common - putative chloramphenicol O-acetyltransferase CLC_0939 20 None None None 153937554 Common - hypothetical protein CLC_1389 3 None None None 153934574 Pathogen - hypothetical protein CLC_0596 1 None None None 153935097 Pathogen - putative DNA-binding protein CLC_2942 1 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 153936803 Common - membrane protein, VanZ family CLC_2667 4 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 153934872 Common - tetratricopeptide repeat family protein CLC_1929 111 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 153935626 Common - transcriptional regulator, PadR family CLC_2233 56 COG1695 COG1695, Predicted transcriptional regulators Transcription 153935554 Common - peptide ABC transporter, Pep4E family, ATP-binding protein CLC_1433 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153937675 Common - hypothetical protein CLC_1692 5 None None None 153934905 Common - spore germination protein CLC_1922 15 None None None 153936984 Common - aspartate/ornithine carbamoyltransferase family protein CLC_2782 228 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 153935516 Common - nitrate reductase, iron-sulfur subunit CLC_1370 156 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 153936184 Common - putative sensory box sigma-54 dependent transcriptional regulator CLC_3383 181 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153935355 Common - spore germination protein CLC_1925 13 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 153935479 Common - putative peptidase CLC_3585 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153936192 Common cobD cobalamin biosynthesis protein CobD CLC_0969 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 153935107 Common - hypothetical protein CLC_3160 3 None None None 153936270 Common - rubredoxin/rubrerythrin CLC_3124 23 COG1592 COG1592, Rubrerythrin Energy production and conversion 153935218 Common - hypothetical protein CLC_0521 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153935888 Common - hydrolase, NUDIX family CLC_0548 39 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153935101 Common - peptide/opine/nickel uptake ABC transporter, PepT family, permease protein CLC_1697 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153935607 Common - transcriptional regulator, GntR family CLC_2666 139 COG1725 COG1725, Predicted transcriptional regulators Transcription 153934981 Common - transcriptional regulator, TetR family CLC_1283 13 COG1309 AcrR, Transcriptional regulator Transcription 153934529 Common - hypothetical protein CLC_3455 9 None None None 153936320 Common - putative lipoprotein CLC_0384 1 None None None 153934522 Common - putative NADPH-dependent FMN reductase CLC_0907 52 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153935602 Common - CAAX amino terminal protease family protein CLC_0981 6 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 153934753 Common - bacterial microcompartments family protein CLC_2062 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 153936371 Pathogen - hypothetical protein CLC_0852 1 None None None 153937619 Common - propanediol utilization protein PduL-like protein CLC_2049 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 153937091 Common - TPR domain protein CLC_1425 1 None None None 153936566 Pathogen - hypothetical protein CLC_0295 1 None None None 153936530 Common rplB ribosomal protein L2 CLC_3422 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 153937060 Pathogen - hypothetical protein CLC_2373 1 COG3655 COG3655, Predicted transcriptional regulator Transcription 153934952 Common - TPR domain protein CLC_2823 1 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 153936049 Common - putative dipeptidase CLC_3288 184 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 153936696 Common - hypothetical protein CLC_0745 18 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 153935399 Common - putative molybdopterin binding protein CLC_1016 106 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 153937808 Common - ROK family protein CLC_1243 102 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 153935802 Common - acetyltransferase, GNAT family CLC_0962 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153937125 Common - hypothetical protein CLC_2564 2 None None None 153937003 Common - 5-nitroimidazole antibiotic resistance protein CLC_1349 29 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 153936409 Common - putative transcriptional regulator CLC_0346 44 COG1737 RpiR, Transcriptional regulators Transcription 153936554 Pathogen - hypothetical protein CLC_1322 1 None None None 153935391 Common - putative low specificity L-threonine aldolase CLC_2156 80 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 153936548 Common - HDIG domain protein CLC_2880 42 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 153935711 Common - polysaccharide deacetylase family protein CLC_0409 97 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153935791 Common ptsH phosphocarrier protein HPr CLC_2244 132 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 153937715 Common - hypothetical protein CLC_0996 4 None None None 153935130 Common - oxidoreductase, short chain dehydrogenase/reductase family CLC_2221 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153935911 Common - peptide ABC transporter, Pep4E family, ATP-binding protein CLC_1544 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153935938 Common - nitroreductase family protein CLC_0988 48 COG0778 NfnB, Nitroreductase Energy production and conversion 153937445 Common cbiD cobalamin biosynthesis protein CbiD CLC_0991 91 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 153937227 Common spmA spore maturation protein A CLC_0118 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 153936589 Pathogen - hypothetical protein CLC_1410 1 None None None 153934472 Common - transcriptional regulator, RpiR family CLC_0329 79 COG1737 RpiR, Transcriptional regulators Transcription 153936844 Common - radical SAM domain protein CLC_2958 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 153937508 Common - response regulator CLC_0580 222 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 153936912 Common - hypothetical protein CLC_2246 61 COG2510 COG2510, Predicted membrane protein Function unknown 153935523 Pathogen - hypothetical protein CLC_2340 1 None None None 153937440 Common sagG ABC transporter, ATP-binding protein SagG CLC_0566 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937342 Common - putative methylcobalamin:Coenzyme M methyltransferase CLC_1532 66 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 153937752 Common - DedA family protein CLC_2483 117 COG0398 COG0398, Uncharacterized conserved protein Function unknown 153936982 Common spoIIAB anti-sigma F factor CLC_2990 17 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 153937560 Pathogen - hypothetical protein CLC_1133 1 None None None 153934576 Common - hypothetical protein CLC_2450 14 None None None 153934794 Common cobH precorrin-8X methylmutase CLC_0980 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 153937592 Common - putative 2-phosphosulfolactate phosphatase CLC_3533 48 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 153937269 Pathogen - hypothetical protein CLC_1897 1 None None None 153937332 Common - VanZ family protein CLC_2550 16 COG5652 COG5652, Predicted integral membrane protein Function unknown 153934610 Common cbiQ cobalt ABC transporter, permease protein CbiQ CLC_0973 17 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 153935864 Common - HAD-superfamily hydrolase, subfamily IIB CLC_1643 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 153936951 Common - hypothetical protein CLC_1865 1 None None None 153936726 Common - hypothetical protein CLC_0386 7 COG4868 COG4868, Uncharacterized protein conserved in bacteria Function unknown 153935182 Common - putative permease CLC_3166 101 COG0701 COG0701, Predicted permeases General function prediction only 153937683 Common - flagellin protein CLC_0300 121 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153935081 Common - hypothetical protein CLC_1383 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 153937805 Pathogen - hypothetical protein CLC_2172 1 None None None 153935474 Common rpoB DNA-directed RNA polymerase, beta subunit CLC_3433 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 153937660 Common - TraG/TraD family protein CLC_2407 73 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 153937194 Common rpmA ribosomal protein L27 CLC_2884 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 153935172 Common - DHH domain protein CLC_2963 190 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 153935497 Common - cyclic nucleotide-binding domain protein CLC_1077 46 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153934799 Common argS arginyl-tRNA synthetase CLC_1124 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153935845 Common - putative aspartate aminotransferase CLC_1067 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153936537 Common - putative lipoprotein CLC_3547 8 COG5401 COG5401, Spore germination protein General function prediction only 153934568 Common - zinc metalloprotease, aminopeptidase I family CLC_3283 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 153937845 Common - site-specific recombinase, phage integrase family CLC_3307 208 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153935735 Common - putative metal-dependent hydrolase, membrane-bound CLC_3324 13 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 153935137 Common - peptidase family protein CLC_0229 40 COG2234 Iap, Predicted aminopeptidases General function prediction only 153937439 Common bioD dethiobiotin synthase CLC_2182 148 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 153935983 Common recX regulatory protein RecX CLC_3085 20 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 153936266 Common - hypothetical protein CLC_1007 11 None None None 153935268 Common - DNA-binding response regulator CLC_1431 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936380 Common tuf-2 translation elongation factor Tu CLC_3441 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 153937668 Common thiM-1 hydroxyethylthiazole kinase CLC_0524 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 153936939 Pathogen - hypothetical protein CLC_1946 1 None None None 153937698 Common acpS holo-(acyl-carrier-protein) synthase CLC_3344 168 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 153935590 Common - transcriptional regulator, Fur family CLC_3130 133 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153935662 Common - spore germination protein CLC_2228 20 None None None 153935708 Common - oxidoreductase, aldo/keto reductase family CLC_3314 197 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 153936219 Common - hypothetical protein CLC_2415 10 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 153935261 Common sagD streptolysin associated protein SagD CLC_0563 10 COG1944 COG1944, Uncharacterized conserved protein Function unknown 153936710 Common grdD glycine reductase complex component C, alpha subunit CLC_1302 19 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 153937235 Common - hypothetical protein CLC_2226 1 None None None 153934882 Common tyrS-2 tyrosyl-tRNA synthetase CLC_3268 219 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153936518 Common - HDIG domain protein CLC_0581 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 153934533 Common - hypothetical protein CLC_3462 1 None None None 153937207 Common aroQ 3-dehydroquinate dehydratase, type II CLC_1842 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 153934615 Common - hypothetical protein CLC_1688 10 COG5523 COG5523, Predicted integral membrane protein Function unknown 153936591 Pathogen - hypothetical protein CLC_0734 1 None None None 153936356 Common - transposase, IS3 family CLC_0865 147 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153937261 Common - sensory box histidine kinase CLC_2637 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936259 Common - C4-dicarboxylate transporter CLC_1446 46 COG1288 COG1288, Predicted membrane protein Function unknown 153934584 Common ftsZ cell division protein FtsZ CLC_2393 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 153936732 Common - ribosomal protein L7Ae family protein CLC_2266 12 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 153937733 Common recR recombination protein recR CLC_0053 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 153935613 Pathogen - hypothetical protein CLC_1200 1 None None None 153935484 Common radA DNA repair protein radA CLC_3457 221 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 153935013 Common - hypothetical protein CLC_1872 2 None None None 153936032 Common infB translation initiation factor IF-2 CLC_2265 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 153937546 Common - uracil-DNA glycosylase family protein CLC_0071 141 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 153936464 Pathogen - hypothetical protein CLC_1063 1 None None None 153937535 Common - ErfK/YbiS/YcfS/YnhG family protein CLC_0021 13 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153936930 Common - methyl-accepting chemotaxis protein CLC_1690 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153934891 Common dapB-2 dihydrodipicolinate reductase CLC_3063 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 153935298 Common - manganese/zinc/iron chelate uptake ABC transporter, Mzt family, substrate-binding protein CLC_3263 62 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 153937357 Common - glycosyl transferase, group 1 family protein CLC_3003 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153935244 Common - stage III sporulation protein AA CLC_1839 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 153936120 Common - isochorismatase family protein CLC_1001 119 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153935538 Common - hypothetical protein CLC_1359 6 COG4194 COG4194, Predicted membrane protein General function prediction only 153937133 Common - comF protein-like protein CLC_0225 154 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 153934944 Common - transglycosylase, SLT family CLC_3217 176 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153935701 Common - lipoprotein, NLPA family CLC_1138 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 153936911 Common - TrpR family protein CLC_3215 18 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 153935017 Common - hypothetical protein CLC_0488 25 COG2155 COG2155, Uncharacterized conserved protein Function unknown 153935220 Common - peptidase, family M23/M37 CLC_2891 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153937760 Common - hypothetical protein CLC_0460 17 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 153936764 Common - stage III sporulation protein AD CLC_1836 15 None None None 153935039 Common - hypothetical protein CLC_0345 78 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 153937138 Common - DNA-binding protein CLC_3095 85 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 153935976 Common - spore germination protein CLC_2672 15 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 153935194 Common csaA csaA protein CLC_0677 137 COG0073 ARC1, EMAP domain General function prediction only 153936690 Common - hypothetical protein CLC_1809 1 None None None 153936598 Common cstA carbon starvation protein CstA CLC_3252 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 153936794 Common - response regulator CLC_1869 17 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 153936929 Common - nitroreductase family protein CLC_3556 183 COG0778 NfnB, Nitroreductase Energy production and conversion 153936200 Common - hypothetical protein CLC_2708 3 None None None 153935018 Pathogen - hypothetical protein CLC_0820 1 None None None 153937326 Pathogen - hypothetical protein CLC_1366 1 None None None 153937301 Pathogen - hypothetical protein CLC_2111 1 None None None 153935117 Common udgA uracil-DNA glycosylase CLC_0121 156 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 153936302 Common - hypothetical protein CLC_0451 1 None None None 153935093 Pathogen - hypothetical protein CLC_0841 1 None None None 153934597 Pathogen - hypothetical protein CLC_2741 1 None None None 153936582 Common - hypothetical protein CLC_1591 10 COG5523 COG5523, Predicted integral membrane protein Function unknown 153937313 Common - ferritin-like diiron domain protein CLC_1049 27 COG1592 COG1592, Rubrerythrin Energy production and conversion 153937321 Pathogen - hypothetical protein CLC_2934 1 None None None 153936467 Common - hypothetical protein CLC_0421 117 COG2855 COG2855, Predicted membrane protein Function unknown 153936022 Common - phenazine biosynthesis protein, PhzF family CLC_2125 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 153935695 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_2696 185 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153937670 Common - putative endoribonuclease L-PSP CLC_2878 194 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153935575 Common dpaL diaminopropionate ammonia-lyase CLC_2785 168 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 153935825 Common dnaB replicative DNA helicase CLC_3619 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 153937272 Common - amidohydrolase family protein CLC_2780 160 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153935965 Common - putative D-proline reductase, PrdA proprotein CLC_2313 8 None None None 153935683 Common rpiB ribose 5-phosphate isomerase B CLC_0192 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 153934489 Common - hypothetical protein CLC_2814 7 None None None 153936711 Common - sensor histidine kinase CLC_1089 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936773 Common - cysteine synthase family protein CLC_0780 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 153936697 Common rpsT ribosomal protein S20 CLC_2863 178 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 153937641 Common pyrK dihydroorotate dehydrogenase, electron transfer subunit CLC_3148 92 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153934647 Common - putative bacteriocin CLC_0802 2 None None None 153935784 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CLC_1098 111 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 153936673 Common - mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase domain protein CLC_1726 70 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 153937639 Common - hydrogenase maturation protease CLC_1781 1 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 153935387 Common groES chaperonin, 10 kDa CLC_3241 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 153936395 Common ypeB germination protein YpeB CLC_0176 15 None None None 153935346 Common - hypothetical protein CLC_2056 5 COG4812 EutT, Ethanolamine utilization cobalamin adenosyltransferase Amino acid transport and metabolism 153937742 Common - MazG family protein CLC_3513 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 153935544 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CLC_2793 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153937823 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_1765 163 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153936817 Common - hypothetical protein CLC_2601 1 None None None 153936876 Common - glycosyl transferase, group 2 family protein CLC_2575 133 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153935414 Common - csfB protein-like protein CLC_0100 1 None None None 153936174 Common dprA DNA protecting protein DprA CLC_2286 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 153936513 Common - transcriptional regulator, MerR family CLC_1070 37 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 153936909 Common - DNA-binding response regulator CLC_0376 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153934976 Common - ABC transporter, ATP-binding protein CLC_0723 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 153936667 Common - polysaccharide deacetylase family protein CLC_3068 130 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153936234 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase CLC_1601 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 153934520 Common - hypothetical protein CLC_3091 48 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 153935660 Pathogen - hypothetical protein CLC_2003 1 None None None 153935941 Common - putative sensor histidine kinase CLC_0306 175 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 153937184 Common - putative drug resistance ABC transporter, ATP-binding protein CLC_1717 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153937716 Common - hypothetical protein CLC_3349 2 None None None 153935909 Common - hypothetical protein CLC_2152 5 None None None 153936083 Common - transcriptional regulator, AraC family CLC_2207 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153934636 Common nagA N-acetylglucosamine-6-phosphate deacetylase CLC_2711 121 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 153937772 Common - oligopeptide/dipeptide ABC transporter, ATP-binding protein CLC_3056 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 153937624 Common - AP endonuclease, family 2 CLC_2088 47 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153937820 Common - O-methyltransferase family protein CLC_2427 115 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 153937691 Common - cytidine/deoxycytidylate deaminase family protein CLC_0048 217 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 153936660 Common - hypothetical protein CLC_2007 6 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 153937511 Common purF-2 amidophosphoribosyltransferase CLC_2808 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 153936275 Common - phosphoglucomutase/phosphomannomutase family protein CLC_3618 234 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 153936127 Common - hypothetical protein CLC_3540 1 None None None 153936635 Common - lemA family protein CLC_0536 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 153934852 Common - putative cell division protein FtsL CLC_1492 1 None None None 153936749 Common - tfoX domain protein CLC_0771 15 None None None 153936018 Common glmM phosphoglucosamine mutase CLC_3365 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 153936846 Pathogen - hypothetical protein CLC_0613 1 None None None 153936900 Common - putative LexA repressor CLC_0963 162 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 153935334 Common cheD chemotaxis protein CheD CLC_2625 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 153936347 Common - oxidoreductase, NAD-binding CLC_3247 93 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153935935 Pathogen - hypothetical protein CLC_2928 1 None None None 153937813 Common tuf-1 translation elongation factor Tu CLC_3427 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 153936810 Common - hypothetical protein CLC_1436 21 None None None 153935705 Common - hypothetical protein CLC_2099 3 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 153935273 Common phoU phosphate transport system regulatory protein PhoU CLC_2380 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 153935426 Common - metallo-beta-lactamase family protein CLC_0309 18 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153934518 Common - putative phospholipase C CLC_2507 8 None None None 153936889 Common - NADPH-dependent FMN reductase CLC_1901 43 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153935946 Common fhuC ferrichrome ABC transporter, ATP-binding protein CLC_0743 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153936884 Pathogen - hypothetical protein CLC_3030 1 None None None 153934554 Common - ErfK/YbiS/YcfS/YnhG family protein CLC_0950 83 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153934889 Common gap-2 glyceraldehyde-3-phosphate dehydrogenase, type I CLC_1147 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 153936834 Common - PTS system, fructose family, IIA component CLC_1936 139 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 153936325 Common - restriction/helicase domain protein CLC_2028 121 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 153936222 Common - PAP2 family protein CLC_3273 6 None None None 153937632 Common spo0A sporulation transcription factor Spo0A CLC_1816 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937368 Common serS-2 seryl-tRNA synthetase CLC_0584 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937292 Common secE preprotein translocase, SecE subunit CLC_3439 1 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 153935068 Common - putative mannosyltransferase CLC_0156 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153937159 Pathogen - hypothetical protein CLC_1125 1 None None None 153934965 Common - SpoVA family protein CLC_2988 15 None None None 153937143 Common - pyridoxine biosynthesis protein CLC_2676 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 153937617 Common fabH 3-oxoacyl-(acyl-carrier-protein) synthase III CLC_3582 210 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 153936609 Common - putative ATP-dependent helicase CLC_0585 62 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 153934783 Common - hypothetical protein CLC_0923 6 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 153937701 Common - stage III sporulation protein AC CLC_1837 8 None None None 153937810 Common - putative dnaD protein CLC_0792 6 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 153934717 Common spoVS stage V sporulation protein S CLC_2249 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 153937529 Common ha33 hemagglutinin component HA33 CLC_0859 2 None None None 153934766 Common mraZ mraZ protein CLC_1490 140 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 153937421 Common - putative mutator mutT protein CLC_2027 151 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153934509 Common - putative 6-pyruvoyl tetrahydropterin synthase CLC_0882 138 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 153936750 Common - RNA polymerase sigma factor, sigma-70 family CLC_2750 11 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153937165 Common - CBS domain protein CLC_2838 23 COG0517 COG0517, FOG: CBS domain General function prediction only 153937024 Common - transcription activator, effector binding domain protein CLC_1582 34 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 153935455 Common aspB-3 aspartate aminotransferase CLC_2245 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153936071 Common - oxidoreductase, pyridine nucleotide-disulfide family CLC_2781 212 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153935187 Pathogen - hypothetical protein CLC_1745 1 None None None 153937557 Common - DegV family protein CLC_1348 57 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 153934931 Common - transcriptional regulator, MerR family CLC_2067 36 COG0789 SoxR, Predicted transcriptional regulators Transcription 153935993 Common - putative diguanylate cyclase CLC_0139 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153934606 Common ptb phosphate butyryltransferase CLC_3371 160 COG0280 Pta, Phosphotransacetylase Energy production and conversion 153935601 Common - exopolysaccharide biosynthesis family protein CLC_3000 17 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 153936924 Common boNT/A1 botulinum neurotoxin type A1, BoNT/A1 CLC_0862 3 None None None 153934640 Common atpE ATP synthase F0, C subunit CLC_0199 26 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 153937114 Common - pyridine nucleotide-disulfide oxidoreductase CLC_3258 103 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153936117 Common - rrf2 family protein CLC_0343 64 COG1959 COG1959, Predicted transcriptional regulator Transcription 153936076 Common - amino acid permease family protein CLC_1412 167 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153937829 Common rumA-1 23S rRNA (uracil-5-)-methyltransferase RumA CLC_2758 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 153936509 Common - hypothetical protein CLC_2828 12 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153935877 Common cphA cyanophycin synthetase CLC_0168 130 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 153936799 Common xseB exodeoxyribonuclease VII, small subunit CLC_1828 74 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 153937287 Common - calcium-translocating P-type ATPase, PMCA-type CLC_0456 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153935248 Common - metallo-beta-lactamase family protein CLC_0721 82 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153936210 Common - transcriptional regulator, LysR family CLC_1079 193 COG0583 LysR, Transcriptional regulator Transcription 153936545 Common tdk thymidine kinase CLC_0184 81 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 153937453 Common fliS flagellar protein FliS CLC_2608 78 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 153936641 Common - hypothetical protein CLC_3133 61 COG2378 COG2378, Predicted transcriptional regulator Transcription 153935599 Common mraW S-adenosyl-methyltransferase MraW CLC_1491 216 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 153937835 Common - choloylglycine hydrolase family protein CLC_2193 13 COG4927 COG4927, Predicted choloylglycine hydrolase General function prediction only 153935502 Common - small, acid-soluble spore protein CLC_2950 15 None None None 153935674 Common - putative cell division ATP-binding protein FtsE CLC_3334 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 153937379 Common - putative methyltransferase CLC_2349 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 153936894 Common ligT 2'-5' RNA ligase CLC_2702 94 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 153937610 Common - putative helicase CLC_2800 121 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 153935301 Common - peptide/opine/nickel uptake ABC transporter, PepT family, substrate-binding protein CLC_1696 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153935562 Common - hypothetical protein CLC_2751 1 None None None 153937240 Common - hypothetical protein CLC_0407 12 None None None 153934588 Pathogen - hypothetical protein CLC_1259 1 None None None 153935253 Pathogen - hypothetical protein CLC_2733 1 None None None 153936796 Common - hypothetical protein CLC_0574 1 None None None 153937066 Common - hypothetical protein CLC_1626 1 None None None 153935979 Common - fructose-1,6-bisphosphatase CLC_0589 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 153934812 Common - sensor histidine kinase CLC_0666 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 153936527 Common - stress responsive A/B barrel domain protein CLC_2215 30 None None None 153934594 Common - DNA-binding response regulator, LytTr family CLC_1229 57 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 153937212 Common rumA-2 23S rRNA (uracil-5-)-methyltransferase RumA CLC_3312 205 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 153937076 Common - pyridine nucleotide-disulphide oxidoreductase CLC_1121 174 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153935179 Common - ZIP transporter family protein CLC_0189 125 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 153936282 Common cysK-2 cysteine synthase A CLC_1222 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 153937335 Common - putative high-affinity branched chain amino acid ABC transporter, ATP-binding protein CLC_0531 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153936021 Common spoVB-1 stage V sporulation protein B CLC_1471 78 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153936430 Common - PTS system, glucitol/sorbitol-specific, IIC component CLC_3361 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 153935088 Common - hypothetical protein CLC_0438 9 COG3339 COG3339, Uncharacterized conserved protein Function unknown 153937703 Common - peptidase, M20/M25/M40 family CLC_2803 28 COG4187 RocB, Arginine degradation protein (predicted deacylase) Amino acid transport and metabolism 153937119 Common - transcriptional regulator, MerR family CLC_2168 62 COG0789 SoxR, Predicted transcriptional regulators Transcription 153937859 Common rplP ribosomal protein L16 CLC_3418 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 153936814 Common - hypothetical protein CLC_3100 33 COG1915 COG1915, Uncharacterized conserved protein Function unknown 153935618 Common - hypothetical protein CLC_1023 1 None None None 153937325 Common - hypothetical protein CLC_1313 68 COG2323 COG2323, Predicted membrane protein Function unknown 153937204 Common ychF GTP-binding protein YchF CLC_1489 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 153936573 Common - putative transaldolase CLC_3356 104 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 153935726 Common - amino acid/peptide transporter CLC_2105 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 153937790 Common - transcriptional antiterminator, BglG family CLC_2713 29 COG3711 BglG, Transcriptional antiterminator Transcription 153935927 Common - hypothetical protein CLC_0725 1 None None None 153937307 Common - FHA domain protein CLC_3328 60 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 153935886 Common - putative ABC transporter, permease protein CLC_1263 191 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153936407 Common - putative phosphate regulon sensor protein CLC_2385 224 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 153937547 Common - glycosyl transferase, group 1 family protein CLC_2998 202 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153936950 Common - oligopeptide transporter, OPT family CLC_2154 42 COG1297 COG1297, Predicted membrane protein Function unknown 153937152 Common - major facilitator family protein CLC_1704 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153937687 Common - fibronectin-binding protein CLC_1857 79 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 153934789 Common ade adenine deaminase CLC_0353 71 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 153935767 Common - hypothetical protein CLC_3027 3 None None None 153934928 Common gltA-2 glutamate synthase (NADPH), homotetrameric CLC_3246 192 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153934723 Common - lipoprotein, NLPA family CLC_1139 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 153934569 Common - hypothetical protein CLC_0406 9 None None None 153936892 Common - hypothetical protein CLC_2580 5 None None None 153937516 Common - hypothetical protein CLC_1164 14 None None None 153935208 Common prdB D-proline reductase, PrdB subunit, selenocysteine-containing CLC_2329 13 None None None 153936869 Common potA spermidine/putrescine ABC transporter, ATP-binding protein CLC_0618 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153935319 Common - hypothetical protein CLC_0553 1 None None None 153934970 Common - hypothetical protein CLC_1543 29 COG3760 COG3760, Uncharacterized conserved protein Function unknown 153936605 Common gltA-1 glutamate synthase (NADPH), homotetrameric CLC_1671 193 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153937589 Common - putative lipoprotein CLC_2101 2 COG5270 COG5270, PUA domain (predicted RNA-binding domain) Translation, ribosomal structure and biogenesis 153934644 Common - stage III sporulation protein AB CLC_1838 12 None None None 153935856 Common - thiF domain protein CLC_0061 114 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 153934831 Common - xanthine/uracil permease family protein CLC_3115 135 COG2252 COG2252, Permeases General function prediction only 153936289 Common - S4 domain protein CLC_0003 40 COG2501 COG2501, Uncharacterized conserved protein Function unknown 153935153 Common truA-1 tRNA pseudouridine synthase A CLC_1858 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 153935448 Pathogen - hypothetical protein CLC_3272 1 None None None 153935383 Common - hypothetical protein CLC_0926 102 COG2378 COG2378, Predicted transcriptional regulator Transcription 153935710 Common - xanthine dehydrogenase family protein, molybdopterin-binding subunit CLC_1323 118 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 153936185 Common gatC glutamyl-tRNA(Gln) amidotransferase, C subunit CLC_3210 149 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 153934505 Common - putative accessory gene regulator protein B CLC_0389 5 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 153935499 Common - DegV family protein CLC_2445 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 153937278 Common - helicase, Snf2 family CLC_1624 146 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 153937222 Common asrB anaerobic sulfite reductase, subunit B CLC_1014 74 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153935891 Pathogen - hypothetical protein CLC_1285 1 None None None 153936180 Common mtnN MTA/SAH nucleosidase CLC_1508 97 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 153935846 Common - hypothetical protein CLC_0877 12 None None None 153936015 Pathogen - putative lipoprotein CLC_1847 1 None None None 153936447 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family CLC_3204 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 153936145 Common - hypothetical protein CLC_0828 1 None None None 153936657 Common nadD nicotinate nucleotide adenylyltransferase CLC_2881 176 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 153934602 Common - choline/carnitine/betaine transporter CLC_1180 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 153937498 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_1610 245 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 153937759 Common - cytidylyltransferase domain protein CLC_2554 78 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 153934983 Common rpsF ribosomal protein S6 CLC_3627 207 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 153936966 Common hom-1 homoserine dehydrogenase CLC_1667 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 153935628 Common - hypothetical protein CLC_1262 3 None None None 153937739 Common uvrA excinuclease ABC, A subunit CLC_3329 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 153935640 Common msrB methionine-R-sulfoxide reductase CLC_2203 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 153936440 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CLC_3453 198 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 153937386 Common - xanthine dehydrogenase family protein, FAD-binding subunit CLC_0318 50 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 153936078 Common - putative N-acetylmuramoyl-L-alanine amidase CLC_3012 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153936978 Common - hypothetical protein CLC_1314 2 None None None 153936031 Pathogen - hypothetical protein CLC_0801 1 None None None 153936955 Common - putative type I restriction-modification system, M subunit CLC_0732 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 153935580 Common - sodium:alanine symporter family protein CLC_1153 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153936439 Common - DNA-binding response regulator CLC_0958 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935775 Common - ABC transporter, ATP-binding protein CLC_0821 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935812 Common scpB segregation and condensation protein B CLC_1799 160 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 153934482 Common - sodium:alanine symporter family protein CLC_1287 116 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153936314 Pathogen - putative thiaminase I CLC_0826 2 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153935950 Common - peptidase, M16 family CLC_2641 174 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 153937652 Common selA L-seryl-tRNA selenium transferase CLC_2873 72 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 153934703 Common - hypothetical protein CLC_1769 100 COG0393 COG0393, Uncharacterized conserved protein Function unknown 153937247 Common npr-5 thermolysin metallopeptidase CLC_1482 47 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 153936928 Common - regulator of flagellin synthesis FlgM CLC_2616 2 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 153936106 Common - nlpC/P60 family protein CLC_1813 156 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 153934657 Common - oligopeptide/dipeptide ABC transporter, permease protein CLC_3059 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936737 Common - drug resistance ABC transporter, RA2 family, ATP-binding protein CLC_2735 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153935279 Common - hypothetical protein CLC_2469 23 COG3610 COG3610, Uncharacterized conserved protein Function unknown 153936996 Common pepT peptidase T CLC_0513 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 153934681 Pathogen - hypothetical protein CLC_3121 1 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 153937677 Common lon ATP-dependent protease La CLC_3139 208 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 153936542 Pathogen - small acid-soluble spore protein, H-type CLC_1277 1 None None None 153936331 Common mraY-2 phospho-N-acetylmuramoyl-pentapeptide-transferase CLC_1496 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 153935552 Common - hypothetical protein CLC_1503 51 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 153937504 Common recA recA protein CLC_2251 220 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 153936005 Common - ABC transporter, permease protein CLC_1160 193 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153934727 Common spoIVB stage IV sporulation protein B CLC_1817 15 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 153935045 Common - hypothetical protein CLC_0257 1 None None None 153934663 Common - sensor histidine kinase CLC_0377 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936585 Common - aminotransferase family protein CLC_0970 192 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 153935098 Common - hypothetical protein CLC_3285 10 COG5192 BMS1, GTP-binding protein required for 40S ribosome biogenesis Translation, ribosomal structure and biogenesis 153935105 Common - putative cobalt ABC transporter, ATP-binding protein CLC_3394 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 153937081 Common - alanine racemase, N-terminal domain protein CLC_1920 23 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 153936947 Pathogen - hypothetical protein CLC_2740 1 None None None 153935981 Common - hypothetical protein CLC_2918 1 None None None 153936452 Common - putative thioredoxin reductase CLC_1294 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153936615 Common - aminotransferase, DegT/DnrJ/EryC1/StrS family CLC_1997 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 153936490 Common - HAD superfamily (subfamily IA) hydrolase, TIGR02254 CLC_1076 53 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 153934998 Common fabZ beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ CLC_3575 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 153935586 Common serA D-3-phosphoglycerate dehydrogenase CLC_1176 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 153937087 Common - hypothetical protein CLC_2122 13 None None None 153936686 Common - putative high-affinity branched-chain amino acid ABC transporter, permease protein CLC_0529 148 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153936240 Common - thrombospondin type 3 repeat protein CLC_1984 34 None None None 153934933 Common - hypothetical protein CLC_2191 2 None None None 153936564 Common - hypothetical protein CLC_2609 1 None None None 153937254 Pathogen - hypothetical protein CLC_0143 1 None None None 153935731 Pathogen - hypothetical protein CLC_0634 1 None None None 153937001 Common coaBC phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CLC_2367 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 153936521 Common - stage 0 sporulation protein J CLC_3637 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 153935459 Common - hypothetical protein CLC_0881 6 COG5298 COG5298, Uncharacterized protein conserved in bacteria Function unknown 153934751 Common - glycosyl transferase, group 1 family protein CLC_2999 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153935393 Common - transcriptional regulator, RpiR family CLC_0328 78 COG1737 RpiR, Transcriptional regulators Transcription 153935751 Common - ABC transporter, ATP-binding protein CLC_1895 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153936757 Pathogen - hypothetical protein CLC_2201 1 None None None 153935281 Common - putative lipoate-protein ligase A CLC_0755 87 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 153934870 Common - sensory box-containing [Fe] hydrogenase CLC_1774 36 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 153936043 Common - putative xanthine dehydrogenase accessory factor CLC_2790 120 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 153937009 Common - RNA methyltransferase, TrmH family, group 3 CLC_3447 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 153935715 Common - desulfoferrodoxin CLC_3278 28 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 153935051 Common - putative lipoate-protein ligase A CLC_1661 82 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 153936397 Common - nucleoside transporter, NupC family CLC_0650 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 153934679 Common clpP-1 clp protease CLC_2255 22 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153936073 Common - hypothetical protein CLC_2047 8 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 153935804 Common - hypothetical protein CLC_2231 1 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 153935518 Common - drug resistance ABC transporter, ATP-binding protein CLC_1116 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153935490 Common - hypothetical protein CLC_3309 16 COG1568 COG1568, Predicted methyltransferases General function prediction only 153936478 Common - putative 2-oxoacid:acceptor oxidoreductase, alpha subunit CLC_3367 116 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 153934879 Common - MATE efflux family protein CLC_0120 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153936497 Common - transcriptional regulator, AsnC family CLC_0902 101 COG1522 Lrp, Transcriptional regulators Transcription 153935377 Common - phosphate acetyl/butyryl transferase CLC_3022 110 COG0280 Pta, Phosphotransacetylase Energy production and conversion 153935072 Pathogen - copper amine oxidase domain protein CLC_2451 1 None None None 153935287 Common - hypothetical protein CLC_0543 50 COG3655 COG3655, Predicted transcriptional regulator Transcription 153937433 Common - ABC transporter, ATP-binding/permease protein CLC_0957 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153937042 Common - neuB family protein CLC_2553 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 153936767 Common - PTS system, lactose/cellobiose family, IIC component CLC_3304 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 153936140 Common - hypothetical protein CLC_1840 10 None None None 153936551 Common cheA chemotaxis protein CheA CLC_2622 160 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 153935762 Common pepP xaa-pro aminopeptidase CLC_0465 243 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153935200 Common - KWG leptospira repeat protein CLC_1691 27 None None None 153936132 Common bcd butyryl-CoA dehydrogenase CLC_3109 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153934516 Common - hypothetical protein CLC_3163 2 None None None 153936471 Pathogen - hypothetical protein CLC_0037 1 None None None 153935782 Common - sensor histidine kinase CLC_0324 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936225 Common thrB homoserine kinase CLC_1665 123 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 153935690 Common - HDIG/HD/KH domain protein CLC_2250 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 153936360 Common - sodium:neurotransmitter symporter family protein CLC_1979 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 153936248 Common pcrA ATP-dependent DNA helicase PcrA CLC_3214 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153937317 Common thiC thiamine biosynthesis protein ThiC CLC_2807 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 153937762 Common - PTS system, IIBC components CLC_1382 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153934742 Common - peptide/opine/nickel uptake ABC transporter, PepT family, ATP-binding protein CLC_1394 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936121 Common coaE dephospho-CoA kinase CLC_2910 208 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 153935437 Common - CAAX amino terminal protease family protein CLC_1346 15 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 153937575 Pathogen - hypothetical protein CLC_0798 1 None None None 153934864 Common - hypothetical protein CLC_3212 1 None None None 153935049 Common - putative 5-methyltetrahydrofolate--homocysteine methyltransferase CLC_1650 181 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 153936874 Common - hypothetical protein CLC_0250 6 None None None 153937413 Common - PTS system, glucose/maltose-specfic, IIBC component CLC_0347 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153937055 Common - putative 3-oxoacyl-(acyl-carrier-protein) synthase III CLC_2457 199 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 153937778 Common acoL TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase CLC_1660 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153937411 Common glvA-3 maltose-6'-phosphate glucosidase CLC_0348 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 153936765 Pathogen - hypothetical protein CLC_0504 1 None None None 153935404 Common - HDIG domain protein CLC_3264 120 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 153937872 Common - hypothetical protein CLC_1547 12 COG5418 COG5418, Predicted secreted protein Function unknown 153934806 Common - hypothetical protein CLC_0672 3 COG0640 ArsR, Predicted transcriptional regulators Transcription 153934977 Common - response regulator CLC_0307 207 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 153935401 Common - putative methyltransferase CLC_1517 134 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 153936195 Common - putative [Fe] hydrogenase, electron-transfer subunit CLC_1791 194 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 153934942 Common - putative lipoprotein CLC_3129 2 None None None 153937030 Common - PP-loop family protein CLC_3239 169 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153935064 Common - putative high-affinity branched-chain amino acid ABC transporter, amino acid-binding protein CLC_0527 154 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153934959 Common - sensor histidine kinase CLC_0843 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153934737 Common - DNA topoisomerase CLC_1540 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 153936694 Common - polysaccharide biosynthesis protein CLC_2595 66 COG1861 SpsF, Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog Cell envelope biogenesis, outer membrane 153935144 Pathogen - hypothetical protein CLC_2332 1 None None None 153936903 Common - drug/metabolite transporter, DMT family CLC_0948 83 COG2510 COG2510, Predicted membrane protein Function unknown 153935534 Common - acetyltransferase, GNAT family CLC_1084 6 COG0456 RimI, Acetyltransferases General function prediction only 153937744 Common - transcriptional regulator, MarR family CLC_1560 10 COG1846 MarR, Transcriptional regulators Transcription 153935972 Common - flagellar biosynthesis domain protein CLC_2524 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 153935189 Common - acyl-CoA dehydrogenase family protein CLC_3230 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153936828 Common - potassium uptake protein, TrkH family CLC_3037 122 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153936087 Common - sodium:alanine symporter family protein CLC_1152 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153937105 Common - glycosyl transferase, group 2 family protein CLC_2487 102 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153937580 Common - putative ABC transporter, permease protein CLC_0897 6 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 153934664 Common glf UDP-galactopyranose mutase CLC_2558 55 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 153934986 Common - dinitrogenase iron-molybdenum cofactor family protein CLC_2146 31 COG1433 COG1433, Uncharacterized conserved protein Function unknown 153935075 Common - hypothetical protein CLC_0103 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 153936024 Common - hypothetical protein CLC_1219 2 None None None 153937239 Pathogen - hypothetical protein CLC_3617 1 None None None 153936922 Common - PTS system, glucose/glucoside family, IIBC component CLC_0336 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153936998 Common - cell cycle protein, FtsW/RodA/SpoVE family CLC_3327 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 153934846 Common - transcriptional regulator, GntR family/aminotransferase, classes I and II CLC_1980 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153936143 Common - aminotransferase, classes I and II CLC_1908 231 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 153937864 Common greA-2 transcription elongation factor GreA CLC_3483 204 COG0782 GreA, Transcription elongation factor Transcription 153934850 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CLC_1027 196 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153935015 Common - hypothetical protein CLC_3103 31 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 153935988 Common - radical SAM domain protein CLC_0154 94 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 153935937 Common - hypothetical protein CLC_1522 2 None None None 153937209 Common - proline racemase CLC_2326 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 153935780 Common - transcriptional regulator, AraC family CLC_0367 29 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153937131 Common rluB ribosomal large subunit pseudouridine synthase B CLC_1755 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 153935463 Common - glycosyl transferase, group 1 family protein CLC_3564 154 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153934485 Common rplL ribosomal protein L7/L12 CLC_3434 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 153935536 Pathogen - hypothetical protein CLC_2147 1 None None None 153934617 Common - glycine cleavage system, dihydrolipoamide dehydrogenase CLC_0754 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153936386 Common - hypothetical protein CLC_2649 4 None None None 153936783 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase CLC_2815 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 153937350 Common - hypothetical protein CLC_0726 5 None None None 153935742 Common crt 3-hydroxybutyryl-CoA dehydratase CLC_3112 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153937827 Common - hypothetical protein CLC_0731 5 None None None 153936066 Common - GIY-YIG domain protein CLC_3114 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 153935615 Common - hypothetical protein CLC_2462 24 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153936945 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CLC_1376 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153937662 Common - transcriptional regulator, TetR family CLC_3223 2 COG1309 AcrR, Transcriptional regulator Transcription 153937727 Common - hypothetical protein CLC_1315 8 None None None 153934979 Common nagE PTS system, N-acetylglucosamine-specific, IIBC component CLC_2715 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153934695 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta region CLC_3385 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 153935967 Common - GTP-binding protein CLC_2982 228 COG2262 HflX, GTPases General function prediction only 153936290 Common - hypothetical protein CLC_2181 7 COG5566 COG5566, Uncharacterized conserved protein Function unknown 153936154 Common - peptidase, U32 family CLC_2426 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 153935166 Common polA DNA polymerase I CLC_2911 221 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 153937328 Common - hypothetical protein CLC_3340 13 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 153937704 Common - DNA-binding response regulator CLC_0331 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937053 Common - sensor histidine kinase CLC_2235 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935129 Common - putative calcium-translocating P-type ATPase, PMCA-type CLC_2509 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153937116 Common - ABC transport ATP-binding/permease protein CLC_1103 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153936469 Pathogen - hypothetical protein CLC_2577 1 None None None 153936109 Common - putative ABC transporter, substrate-binding protein CLC_1205 54 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153935974 Common - lipase CLC_0916 7 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 153935295 Common - von Willebrand factor type A domain protein CLC_3098 32 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 153936849 Common treC alpha,alpha-phosphotrehalase CLC_1934 164 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 153935476 Common clpX ATP-dependent Clp protease, ATP-binding subunit ClpX CLC_3141 232 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 153935011 Common - DHH family protein CLC_3622 91 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 153935222 Common - hypothetical protein CLC_0404 17 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 153937186 Common cadA cadmium-translocating P-type ATPase CLC_0551 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153936842 Common - putative tetracycline resistance protein CLC_2046 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 153936734 Common - hypothetical protein CLC_2347 27 None None None 153935091 Common - sensor histidine kinase CLC_1414 149 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 153937693 Common atpA ATP synthase F1, alpha subunit CLC_0202 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 153935622 Common - NAD-dependent deacetylase CLC_0094 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 153935132 Common - AP endonuclease, family 2 CLC_3144 12 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153934778 Common asrA anaerobic sulfite reductase, subunit A CLC_1013 32 None None None 153937344 Common - sodium:dicarboxylate symporter family protein CLC_3211 123 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 153936427 Common - metallo-beta-lactamase family protein CLC_2767 47 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153937447 Pathogen - hypothetical protein CLC_2037 1 None None None 153937833 Common - xanthine dehydrogenase family protein, iron-sulfur binding protein CLC_2726 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 153936252 Common - hypothetical protein CLC_0532 22 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 153937754 Common - putative phage infection protein CLC_1045 63 COG1511 COG1511, Predicted membrane protein Function unknown 153935184 Common - BioY family protein CLC_0960 114 COG1268 BioY, Uncharacterized conserved protein General function prediction only 153935862 Common - formylmethanofuran dehydrogenase E subunit-related protein CLC_1695 38 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 153935139 Common - hypothetical protein CLC_2102 2 None None None 153934688 Common - sensor histidine kinase CLC_1104 15 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 153934661 Common acoX acetoin catabolism protein X CLC_1658 15 COG3199 COG3199, Uncharacterized conserved protein Function unknown 153937267 Common - sensor histidine kinase CLC_3251 115 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 153935577 Pathogen - hypothetical protein CLC_1309 1 None None None 153934562 Common - hypothetical protein CLC_1279 1 None None None 153935720 Common - hypothetical protein CLC_1905 7 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 153934474 Common pstC phosphate ABC transporter, permease protein PstC CLC_2383 231 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 153935906 Common tgt queuine tRNA-ribosyltransferase CLC_2970 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 153937199 Common - endoribonuclease L-PSP family protein CLC_1942 31 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153934556 Common - putative RNA-binding protein CLC_2882 89 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 153935650 Common - putative phosphoenolpyruvate synthase CLC_2454 194 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 153936751 Pathogen - hypothetical protein CLC_3277 1 None None None 153936539 Common - hypothetical protein CLC_1400 5 None None None 153937569 Common - putative cell wall teichoic acid glycosylation protein GtcA CLC_0357 23 COG2246 COG2246, Predicted membrane protein Function unknown 153936524 Common recJ single-stranded-DNA-specific exonuclease RecJ CLC_2638 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 153937279 Common argH argininosuccinate lyase CLC_2543 229 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 153937192 Common - hypothetical protein CLC_0818 2 None None None 153935495 Common - putative DNA-binding protein CLC_1289 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 153937160 Common fliA RNA polymerase sigma factor for flagellar operon FliA CLC_2516 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 153936583 Common hisD histidinol dehydrogenase CLC_1598 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 153936760 Common - pyruvate ferredoxin oxidoreductase CLC_1235 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 153935110 Common grdA glycine reductase complex component A, selenocysteine-containing CLC_1300 7 None None None 153937070 Common - transcriptional regulator, GntR family CLC_2010 137 COG1725 COG1725, Predicted transcriptional regulators Transcription 153935957 Common gltS sodium/glutamate symporter CLC_0715 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 153935170 Common - polysaccharide biosynthesis protein CLC_3007 41 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153937437 Common - transcriptional regulator, AraC family CLC_1565 126 COG5564 COG5564, Predicted TIM-barrel enzyme, possibly a dioxygenase General function prediction only 153935312 Common - transcriptional regulator, AraC family CLC_1031 129 COG4936 PocR, Predicted sensor domain Signal transduction mechanisms / Transcription 153936263 Common fabG-2 3-oxoacyl-[acyl-carrier-protein] reductase CLC_3578 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153935525 Common - hypothetical protein CLC_1036 1 None None None 153936937 Common - redox family protein CLC_1554 13 None None None 153937562 Common - GIY-YIG domain protein CLC_3290 90 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 153935636 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase CLC_0254 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 153936683 Common - pyrophosphatase, MutT/nudix family CLC_1442 119 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153936297 Common gerAA spore germination protein CLC_2673 15 None None None 153936016 Pathogen - hypothetical protein CLC_3097 1 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 153935057 Pathogen - hypothetical protein CLC_3117 1 None None None 153937593 Common - acetyltransferase domain protein CLC_0953 3 COG3981 COG3981, Predicted acetyltransferase General function prediction only 153937377 Pathogen - hypothetical protein CLC_0944 1 None None None 153937630 Pathogen - D-alanyl carrier protein-like protein CLC_2461 1 None None None 153937405 Common - hypothetical protein CLC_0597 68 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153936771 Common - putative cadmium resistance transcriptional regulator CadC CLC_0550 80 COG0640 ArsR, Predicted transcriptional regulators Transcription 153934599 Common - RNA-binding protein CLC_0230 227 COG2183 Tex, Transcriptional accessory protein Transcription 153937522 Common mgtE magnesium transporter CLC_1174 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 153935457 Pathogen - hypothetical protein CLC_2133 1 None None None 153935504 Common - dihydrouridine synthase CLC_3485 218 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 153935670 Common - hypothetical protein CLC_2070 5 COG1846 MarR, Transcriptional regulators Transcription 153934895 Common - sigma-54 dependent transcriptional regulator CLC_3106 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153935511 Common - DNA-binding response regulator CLC_2079 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935001 Common - transcriptional regulator, MarR family CLC_1065 11 COG1846 MarR, Transcriptional regulators Transcription 153937455 Common - hypothetical protein CLC_2938 1 None None None 153937022 Common - hypothetical protein CLC_0020 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 153934764 Common - hypothetical protein CLC_2066 11 None None None 153934862 Common - putative acyl-CoA synthetase CLC_2456 107 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153937361 Common - hypothetical protein CLC_2274 10 COG0628 PerM, Predicted permease General function prediction only 153937544 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_1930 157 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 153936006 Common argR arginine repressor CLC_1822 52 COG1438 ArgR, Arginine repressor Transcription 153934535 Common - conserved hypothetical protein TIGR00268 CLC_0152 70 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 153934642 Common cobU cobinamide kinase / cobinamide phosphate guanyltransferase CLC_0964 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 153936207 Common rpoC DNA-directed RNA polymerase, beta' subunit CLC_3432 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 153934954 Common - hypothetical protein CLC_2434 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 153935119 Pathogen - hypothetical protein CLC_1875 1 None None None 153936354 Common yfiA ribosomal subunit interface protein CLC_0226 173 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 153937527 Common - hypothetical protein CLC_0159 2 None None None 153934896 Common - CoA-transferase, A subunit CLC_2723 111 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 153934715 Common - ABC transporter, ATP-binding protein CLC_3045 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153934967 Common - sigma-54 dependent transcriptional regulator CLC_1904 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153936543 Common rpsK ribosomal protein S11 CLC_3398 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 153937784 Common acpP-1 acyl carrier protein CLC_2304 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153937622 Pathogen - hypothetical protein CLC_2636 1 None None None 153935597 Common - hypothetical protein CLC_1606 7 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 153935837 Common - mechanosensitive ion channel family protein CLC_3630 182 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 153937484 Common - sigma-54 dependent transcriptional regulator CLC_3303 160 COG3933 COG3933, Transcriptional antiterminator Transcription 153935793 Common - vanW-like family protein CLC_0270 37 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 153937396 Common - hypothetical protein CLC_2662 103 COG0393 COG0393, Uncharacterized conserved protein Function unknown 153934918 Common mscL large conductance mechanosensitive channel protein CLC_0611 137 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 153934904 Common - PHP domain protein CLC_0709 108 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 153934858 Pathogen - hypothetical protein CLC_2419 1 None None None 153936458 Common - sensor histidine kinase CLC_0332 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935321 Common - putative DNA-binding protein CLC_1568 15 COG1476 COG1476, Predicted transcriptional regulators Transcription 153937077 Common spoIIAA anti-sigma F factor antagonist CLC_2991 72 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 153935913 Common - hypothetical protein CLC_0302 17 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 153935235 Common - nitroreductase family protein CLC_0931 93 COG0778 NfnB, Nitroreductase Energy production and conversion 153935026 Common - transcriptional regulator, TetR family CLC_1990 16 COG1309 AcrR, Transcriptional regulator Transcription 153935669 Common - acetyltransferase, GNAT family CLC_0601 3 COG0456 RimI, Acetyltransferases General function prediction only 153936161 Common - oxidoreductase, pyridine nucleotide-disulphide family CLC_3377 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153936819 Common - major cold shock protein CLC_1422 180 COG1278 CspC, Cold shock proteins Transcription 153937330 Common - site-specific recombinase, phage integrase family CLC_1815 38 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153934844 Common - hypothetical protein CLC_1177 46 COG4198 COG4198, Uncharacterized conserved protein Function unknown 153934699 Common rpoZ DNA-directed RNA polymerase, omega subunit CLC_2368 41 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 153936675 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_2730 195 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153936665 Common trmB tRNA (guanine-N(7)-)-methyltransferase CLC_0573 77 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 153937014 Common - hypothetical protein CLC_2474 5 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 153937600 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 CLC_3128 160 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 153935560 Common - DJ-1 family protein CLC_2643 173 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 153937110 Common - hypothetical protein CLC_2002 2 None None None 153936115 Pathogen - hypothetical protein CLC_2742 1 None None None 153936155 Common - hypothetical protein CLC_2688 8 None None None 153935241 Common - hypothetical protein CLC_3369 14 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153937637 Pathogen - hypothetical protein CLC_0977 2 None None None 153937229 Common - hypothetical protein CLC_0880 6 None None None 153937283 Common spoIID stage II sporulation protein D CLC_0208 44 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 153936515 Common amyB beta-amylase CLC_1245 2 None None None 153936700 Common lonB ATP-dependent protease LonB CLC_3140 244 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 153934493 Common - flaG family protein CLC_2610 15 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 153936741 Common - transcriptional regulator, AraC family CLC_0768 101 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 153935871 Common - xanthine/uracil permease family protein CLC_2798 136 COG2252 COG2252, Permeases General function prediction only 153936770 Common - GGDEF domain protein CLC_1954 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153935283 Common - radical SAM domain protein CLC_1119 53 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 153935995 Common - putative excinuclease ABC, A subunit CLC_2700 247 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 153935703 Common cobB cobyrinic acid a,c-diamide synthase CLC_0979 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 153937718 Pathogen - hypothetical protein CLC_1708 1 None None None 153937740 Common - xanthine/uracil permease family protein CLC_2784 124 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 153934638 Common cheY chemotaxis protein CheY CLC_2620 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 153934796 Pathogen uviB bacteriocin UviB CLC_1459 1 None None None 153935336 Common - iron-sulfur cluster-binding protein CLC_3102 28 COG1141 Fer, Ferredoxin Energy production and conversion 153935559 Common glpT glycerol-3-phosphate transporter CLC_1123 146 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153934542 Common - iron compound ABC transporter, permease protein CLC_0370 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153936633 Common divIVA cell-division initiation protein DivIVA CLC_1506 34 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 153937629 Common - transcriptional regulator, GntR family CLC_0535 219 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153936707 Common - putative N-acetylmuramoyl-L-alanine amidase CLC_3013 180 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153937391 Common - putative sugar ABC transporter, permease protein CLC_0278 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 153935120 Common - hypothetical protein CLC_2485 5 None None None 153936050 Common pfl formate acetyltransferase 1 CLC_3126 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 153937366 Pathogen - hypothetical protein CLC_2017 1 None None None 153936864 Common glpX fructose-1,6-bisphosphatase, class II CLC_2489 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 153935263 Common - DNA-binding protein CLC_2298 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 153936319 Common - putative ABC transporter, permease protein CLC_1919 24 COG4721 COG4721, Predicted membrane protein Function unknown 153935944 Common - xanthine dehydrogenase family protein, molybdopterin-binding subunit CLC_2728 112 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 153935569 Common arcA-2 arginine deiminase CLC_1617 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 153935255 Common - hypothetical protein CLC_1848 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 153937305 Common - hypothetical protein CLC_0185 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 153936257 Common arsC anaerobic sulfite reductase, subunit C CLC_1015 89 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 153936217 Common - N-acetylmuramoyl-L-alanine amidase CLC_1469 142 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153936189 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_3616 84 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 153936349 Common - hypothetical protein CLC_1994 11 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153935542 Common - nucleoside recognition domain protein CLC_2346 15 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 153936342 Common - transcriptional regulator, MarR family CLC_0122 3 COG1846 MarR, Transcriptional regulators Transcription 153935672 Pathogen - hypothetical protein CLC_0170 1 None None None 153937295 Common cbiM cobalamin biosynthesis protein CbiM CLC_0971 90 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 153937214 Common - exopolysaccharide biosynthesis protein CLC_2599 172 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153934911 Common - ABC transporter, ATP-binding protein CLC_3158 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153936449 Common - HD domain protein CLC_0624 62 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 153937276 Common - flagellar protein FlbD CLC_2528 24 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 153935083 Common - cysteine-rich domain protein CLC_2484 57 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 153934660 Common - putative DNA-binding protein CLC_0790 11 COG1396 HipB, Predicted transcriptional regulators Transcription 153937846 Common - phosphodiesterase, MJ0936 family CLC_3120 67 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153936090 Pathogen - hypothetical protein CLC_0738 1 None None None 153935651 Common - putative ATP phosphoribosyltransferase regulatory subunit CLC_1596 237 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 153934899 Common - HD domain protein CLC_0418 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 153937367 Pathogen - hypothetical protein CLC_1948 1 None None None 153934855 Common pepIP proline iminopeptidase CLC_1977 123 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153936520 Common - MATE efflux family protein CLC_2717 179 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153934555 Common - bacterial microcompartments family protein CLC_2063 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 153936717 Common - sigma-54 dependent transcriptional regulator CLC_0649 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 153937219 Common - putative CoA-substrate-specific enzyme activase CLC_3153 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 153937816 Common - pentapeptide repeat family protein CLC_0628 31 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 153934972 Common - putative type I restriction-modification system, S subunit CLC_0733 79 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 153937392 Common fhs formate--tetrahydrofolate ligase CLC_3487 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 153934639 Common nagB glucosamine-6-phosphate isomerase CLC_2710 80 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 153934646 Common - glutamine amidotransferase, CobB/CobQ family CLC_0466 61 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 153936880 Pathogen - hypothetical protein CLC_0638 1 None None None 153936123 Common - antibiotic ABC transporter, permease protein CLC_1614 4 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 153934537 Common - DNA-binding protein CLC_0899 24 COG1396 HipB, Predicted transcriptional regulators Transcription 153935375 Common - iron-sulfur cluster-binding protein CLC_1527 36 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 153937154 Common - transaldolase CLC_2097 96 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 153935337 Common ffh signal recognition particle protein CLC_2297 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 153935231 Common clpB clpB protein CLC_0449 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 153937028 Pathogen - hypothetical protein CLC_1141 1 None None None 153934914 Common - ABC transporter, ATP-binding protein CLC_2020 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153936264 Common ackA acetate kinase CLC_2308 162 COG0282 ackA, Acetate kinase Energy production and conversion 153934785 Common - MORN repeat protein CLC_1536 25 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 153936898 Common purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase CLC_2771 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 153936187 Common - methyl-accepting chemotaxis protein CLC_1716 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937815 Common - hypothetical protein CLC_0805 2 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 153936701 Pathogen - hypothetical protein CLC_1195 1 None None None 153935417 Common - glycosyl transferase, group 2 family protein CLC_1758 115 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153934884 Common - hypothetical protein CLC_0823 5 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 153936171 Common fliE flagellar hook-basal body complex protein FliE CLC_2538 77 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 153934532 Common - oxidoreductase, 2-nitropropane dioxygenase family CLC_3584 138 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 153935529 Common - putative DNA-binding protein CLC_2218 57 COG1476 COG1476, Predicted transcriptional regulators Transcription 153935330 Common - glycosyl transferase, group 2 family protein CLC_2044 174 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153934544 Common hprK HPr(Ser) kinase/phosphatase CLC_2480 77 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 153936317 Common - CAAX amino terminal protease family protein CLC_0993 9 None None None 153935676 Common - beta-N-acetylglucosaminidase CLC_3015 9 COG4193 LytD, Beta- N-acetylglucosaminidase Carbohydrate transport and metabolism 153934632 Common - transcriptional regulator, GntR family CLC_0615 110 COG1725 COG1725, Predicted transcriptional regulators Transcription 153935146 Common - amino acid permease family protein CLC_1812 32 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153936678 Common - putative oligopeptide ABC transporter, permease protein CLC_1267 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936885 Common - hypothetical protein CLC_0686 1 None None None 153936648 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_3612 137 COG2081 COG2081, Predicted flavoproteins General function prediction only 153935366 Common - peptide/opine/nickel uptake ABC transporter, PepT family, ATP-binding protein CLC_1395 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153935658 Common - DNA-binding response regulator CLC_0354 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937712 Common - putative R-2-hydroxyglutaryl-CoA dehydratase subunit CLC_3104 12 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 153937640 Common - hypothetical protein CLC_0746 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 153937645 Common - UDP-glucose/GDP-mannose dehydrogenase family CLC_3010 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 153935348 Common - hypothetical protein CLC_1684 25 COG3945 COG3945, Uncharacterized conserved protein Function unknown 153935214 Common - hypothetical protein CLC_0919 74 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 153936156 Pathogen - hypothetical protein CLC_0315 1 None None None 153935494 Common - mgtC family protein CLC_0140 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 153934712 Common metA homoserine O-succinyltransferase CLC_1818 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 153937598 Common - aminotransferase, classes I and II CLC_1437 238 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 153936391 Common arcA-1 arginine deiminase CLC_0113 58 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 153935412 Common dnaA chromosomal replication initiator protein DnaA CLC_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 153937526 Common - hypothetical protein CLC_1826 9 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 153935667 Common - alcohol dehydrogenase, iron-containing CLC_1475 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 153934908 Common - antibiotic ABC transporter, ATP-binding protein CLC_2210 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935329 Common - ATP-dependent DNA helicase, UvrD/REP family CLC_2031 224 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153937786 Common - putative macrolide efflux transporter, RND family, MFP subunit CLC_0132 95 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153936413 Pathogen - hypothetical protein CLC_1319 1 None None None 153935540 Common - methyl-accepting chemotaxis protein CLC_3123 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937265 Common - transcriptional regulator, GntR family CLC_1181 15 COG2188 PhnF, Transcriptional regulators Transcription 153934878 Common - hypothetical protein CLC_1651 1 None None None 153937294 Common - hypothetical protein CLC_2831 36 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 153937611 Common - peptidase, M20/M25/M40 family CLC_2779 189 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 153937375 Common - heat shock protein CLC_0886 157 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 153935717 Common - hypothetical protein CLC_0153 72 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 153936359 Common - ABC transporter, ATP-binding protein CLC_1406 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153934719 Common - HIT family protein CLC_1860 161 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 153934961 Common atpC ATP synthase F1, epsilon subunit CLC_0205 96 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 153936329 Common - transglutaminase domain protein CLC_3084 12 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 153936777 Common - hypothetical protein CLC_1117 8 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 153937711 Pathogen - hypothetical protein CLC_2240 1 None None None 153936628 Common - oxidoreductase, zinc-binding dehydrogenase family CLC_2087 196 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153936056 Common cbiG cobalamin biosynthesis protein CbiG CLC_1004 90 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 153937010 Common rodA-2 rod shape-determining protein RodA CLC_2892 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 153936367 Common - transcriptional regulator, MerR family CLC_0909 54 COG0789 SoxR, Predicted transcriptional regulators Transcription 153937256 Common - acetyltransferase, GNAT family CLC_1034 23 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 153935053 Common - radical SAM domain protein CLC_0636 108 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 153934504 Common ribE riboflavin synthase, alpha subunit CLC_2764 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 153934512 Common - acetyltransferase, GNAT family CLC_0310 12 None None None 153937373 Common mfd transcription-repair coupling factor CLC_3517 235 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 153937550 Common - hypothetical protein CLC_0822 1 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 153937839 Common - DNA-binding response regulator CLC_3521 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935936 Pathogen - hypothetical protein CLC_0647 1 None None None 153937309 Common brnQ-2 branched-chain amino acid transport system II carrier protein CLC_0869 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 153934822 Common glpP glycerol uptake operon antiterminator regulatory protein CLC_2644 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 153935506 Common - iron-sulfur cluster-binding protein CLC_0263 131 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 153936052 Common - hypothetical protein CLC_0896 75 COG1683 COG1683, Uncharacterized conserved protein Function unknown 153935029 Common - hypothetical protein CLC_1955 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 153936541 Common - putative spore coat protein CLC_0157 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 153936639 Common pykA pyruvate kinase CLC_3315 232 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 153935270 Common - Orn/Lys/Arg decarboxylase CLC_0101 90 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 153937457 Common - transcriptional regulator, ArsR family CLC_0235 107 COG0640 ArsR, Predicted transcriptional regulators Transcription 153937705 Common thiE thiamine-phosphate pyrophosphorylase CLC_0523 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 153936279 Common - ABC transporter, permease protein CLC_2083 18 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153936045 Common - hypothetical protein CLC_0544 2 None None None 153937223 Common proC pyrroline-5-carboxylate reductase CLC_3092 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 153936075 Common - hypothetical protein CLC_1646 2 None None None 153935687 Common rpsA ribosomal protein S1 CLC_1202 224 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 153935325 Common - transcriptional regulator, DeoR family CLC_1644 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153937167 Common aroB 3-dehydroquinate synthase CLC_1507 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 153936946 Common - putative amino acid decarboxylase CLC_0299 110 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 153934763 Common - YGGT family protein CLC_1504 29 None None None 153935186 Common - hypothetical protein CLC_2085 50 COG3655 COG3655, Predicted transcriptional regulator Transcription 153936135 Common - putative transposase CLC_2720 131 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153936030 Common - hypothetical protein CLC_2468 52 COG2966 COG2966, Uncharacterized conserved protein Function unknown 153934849 Common - sensor histidine kinase CLC_2211 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 153934561 Pathogen - hypothetical protein CLC_2951 1 None None None 153937112 Common - hypothetical protein CLC_0177 58 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 153935869 Common rfbB dTDP-glucose 4,6-dehydratase CLC_2000 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 153936334 Common deaD ATP-dependent RNA helicase DeaD CLC_1723 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153934926 Common - hypothetical protein CLC_2761 97 COG0730 COG0730, Predicted permeases General function prediction only 153934867 Common - putative V-type ATPase, G subunit CLC_2504 3 None None None 153935113 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CLC_1438 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153936634 Common cobC alpha-ribazole phosphatase CLC_0874 183 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 153935854 Common - hypothetical protein CLC_1916 24 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 153937346 Common - hypothetical protein CLC_0164 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 153935594 Common - putative cell wall hydrolase CLC_2818 9 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 153935914 Common - transcriptional regulator, Fur family CLC_2431 191 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153937380 Common hypA hydrogenase nickel insertion protein HypA CLC_0508 72 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 153936062 Common - hypothetical protein CLC_0783 135 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153936113 Common - hypothetical protein CLC_3319 99 COG0391 COG0391, Uncharacterized conserved protein Function unknown 153936505 Common - putative lipoprotein CLC_1855 1 COG4247 Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) Lipid metabolism 153936400 Common - dipeptidase CLC_1126 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153937415 Common gmk guanylate kinase CLC_2369 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 153935620 Common - B3/4 domain protein CLC_1071 37 COG3382 COG3382, Uncharacterized conserved protein Function unknown 153935396 Common atpG ATP synthase F1, gamma subunit CLC_0203 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 153935161 Pathogen - DNA-binding protein CLC_0791 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 153935224 Common - transcriptional regulator, MarR family CLC_2163 36 COG1846 MarR, Transcriptional regulators Transcription 153936724 Pathogen - hypothetical protein CLC_0590 1 None None None 153935796 Common - transcriptional antiterminator, BglG family CLC_2629 29 COG3711 BglG, Transcriptional antiterminator Transcription 153937512 Common - rubredoxin CLC_1292 74 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 153936595 Common - hypothetical protein CLC_0054 3 None None None 153935058 Common - glyoxalase family protein CLC_1563 8 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153935192 Common - single-strand binding domain protein CLC_3066 12 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 153935452 Pathogen - hypothetical protein CLC_1350 1 None None None 153937531 Common - CAAX amino terminal protease family protein CLC_1114 5 None None None 153936105 Common - hypothetical protein CLC_0756 2 None None None 153937663 Common rplQ ribosomal protein L17 CLC_3395 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 153936529 Pathogen - hypothetical protein CLC_2755 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 153936051 Common galU UTP-glucose-1-phosphate uridylyltransferase CLC_3016 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 153937037 Common iadA isoaspartyl dipeptidase CLC_3379 30 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 153935462 Common glpK glycerol kinase CLC_2660 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 153935532 Common - hypothetical protein CLC_3269 2 None None None 153936920 Common - hypothetical protein CLC_0117 1 None None None 153936274 Common - glycosyltransferase, MGT family CLC_2011 44 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 153936304 Common - nitroreductase family protein CLC_0915 81 COG0778 NfnB, Nitroreductase Energy production and conversion 153935124 Common - hypothetical protein CLC_1638 1 None None None 153935970 Common - hypothetical protein CLC_1756 26 COG3875 COG3875, Uncharacterized conserved protein Function unknown 153934797 Common - transcriptional regulator, DeoR family CLC_1310 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153935133 Common - putative DNA replication protein DnaC CLC_3587 18 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 153935489 Common - hypothetical protein CLC_2118 3 None None None 153934476 Common - PBS lyase HEAT-like repeat protein CLC_2977 9 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 153936666 Pathogen - hypothetical protein CLC_2158 1 None None None 153937587 Common - radical SAM domain protein CLC_1587 126 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 153937566 Common - spore germination protein CLC_0172 17 None None None 153935576 Common - xanthine/uracil permease family protein CLC_1687 134 COG2252 COG2252, Permeases General function prediction only 153935199 Common - hypothetical protein CLC_0112 6 None None None 153935571 Common - stage II sporulation protein R CLC_0174 15 None None None 153937604 Common - V-type ATPase, B subunit CLC_2497 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 153937851 Common - stage II sporulation protein CLC_2861 15 None None None 153936534 Common - glycosyl transferase, group 2 family protein CLC_2395 123 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153935987 Common - hypothetical protein CLC_1352 11 COG1950 COG1950, Predicted membrane protein Function unknown 153935725 Common - putative neutral zinc metallopeptidase CLC_2363 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 153937106 Common - Na+/H+ antiporter family protein CLC_1526 36 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 153936147 Common - patatin-like phospholipase family protein CLC_1523 54 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 153935931 Common rpsG ribosomal protein S7 CLC_3429 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 153936460 Common rnhA ribonuclease HI CLC_0439 157 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 153936798 Common - methionine ABC transporter, MUT family, permease protein CLC_1137 141 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 153935031 Common - hypothetical protein CLC_2542 3 None None None 153935264 Common pflA pyruvate formate-lyase activating enzyme CLC_3125 118 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 153936914 Common npr-4 thermolysin metallopeptidase CLC_1481 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 153936216 Common - hypothetical protein CLC_2926 7 None None None 153934777 Common - hemolysin III CLC_1619 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 153937264 Common - glycosyl hydrolase, family 1 CLC_1244 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 153934988 Common - sensory box histidine kinase CLC_0394 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936669 Common miaB tRNA-i(6)A37 thiotransferase enzyme MiaB CLC_1743 235 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 153934612 Pathogen - hypothetical protein CLC_2939 1 None None None 153934608 Common - carbohydrate uptake ABC transporter, CUT1 family, permease protein CLC_1549 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153937765 Pathogen sagC streptolysin associated protein SagC CLC_0562 5 None None None 153937638 Common - putative phosphate regulon DNA-binding response regulator CLC_2386 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936730 Common motB-2 chemotaxis motB protein CLC_2526 159 COG1360 MotB, Flagellar motor protein Cell motility and secretion 153937725 Common arsR arsenical resistance operon repressor ArsR CLC_0810 140 COG0640 ArsR, Predicted transcriptional regulators Transcription 153935960 Common prsA-1 foldase protein PrsA CLC_3516 168 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 153936026 Common pstB phosphate ABC transporter, ATP-binding protein CLC_2381 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 153937647 Common - ABC transporter, ATP-binding protein CLC_1207 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 153935035 Common - hypothetical protein CLC_1635 16 COG1971 COG1971, Predicted membrane protein Function unknown 153936293 Common - putative transcriptional regulator CLC_1368 118 COG1959 COG1959, Predicted transcriptional regulator Transcription 153935299 Common - hypothetical protein CLC_0224 3 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 153937695 Common - transcriptional regulator, AraC family CLC_1096 126 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153937336 Common - ribosomal protein L7Ae family protein CLC_3431 18 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 153934593 Common - glycosyl transferase, group 1 family protein CLC_3001 184 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153935466 Common - hypothetical protein CLC_2585 13 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 153936159 Common - MATE efflux family protein CLC_2453 150 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153935632 Common - molybdopterin biosynthesis enzyme MoeA / putative molybdate binding domain CLC_1886 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 153935482 Common hrcA heat-inducible transcriptional repressor HrcA CLC_2857 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 153936789 Common - haloacid dehalogenase, IA family protein CLC_3357 195 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153936934 Common - peptide ABC transporter, Pep4E family, permease protein CLC_1429 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153937858 Common - putative lipoprotein CLC_3164 32 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153936177 Common - cold shock protein CLC_1715 166 COG1278 CspC, Cold shock proteins Transcription 153936925 Common - hypothetical protein CLC_0606 4 None None None 153934993 Common dtd D-tyrosyl-tRNA(Tyr) deacylase CLC_2960 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 153934624 Common ytvI sporulation integral membrane protein YtvI CLC_3633 81 COG0628 PerM, Predicted permease General function prediction only 153936170 Common - ABC transporter, ATP-binding protein CLC_1199 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153935884 Common - stage V sporulation protein T CLC_3515 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 153934800 Common cobI precorrin-2 C20-methyltransferase CLC_1002 177 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 153936425 Common - DedA family protein CLC_2482 134 COG0398 COG0398, Uncharacterized conserved protein Function unknown 153937627 Common fldC R-phenyllactate dehydratase, C subunit CLC_3231 38 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153936403 Common - hypothetical protein CLC_1694 98 COG1720 COG1720, Uncharacterized conserved protein Function unknown 153935758 Pathogen - exopolysaccharide biosynthesis protein CLC_2556 3 None None None 153936858 Common - cinA family protein CLC_0267 213 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 153934936 Common - ABC transporter, ATP-binding protein CLC_0616 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153934630 Common - putative thiosulfate sulfurtransferase CLC_2488 147 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153934999 Common - sulfatase family protein CLC_0648 64 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 153937188 Common - transcriptional regulator, Fur family CLC_2707 82 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153935826 Common - dipeptidase family protein CLC_1261 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 153936838 Common - hypothetical protein CLC_2436 161 COG0628 PerM, Predicted permease General function prediction only 153936904 Common - putative lipoprotein CLC_3165 3 None None None 153937123 Common - TPR domain protein CLC_3083 2 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 153936981 Common aroC chorismate synthase CLC_2912 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 153936484 Pathogen - hypothetical protein CLC_0565 1 None None None 153934558 Common - hypothetical protein CLC_1274 7 COG4894 COG4894, Uncharacterized conserved protein Function unknown 153934577 Common lepB-1 signal peptidase I CLC_0630 158 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 153935900 Pathogen - hypothetical protein CLC_2025 1 None None None 153934514 Common - peptide ABC transporter, Pep4E family, permease protein CLC_0334 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153937129 Common - putative drug resistance ABC-2 type transporter, permease protein CLC_0764 152 COG1511 COG1511, Predicted membrane protein Function unknown 153936379 Common fliI flagellar protein export ATPase FliI CLC_2534 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 153936249 Common oxaA membrane protein OxaA CLC_3644 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 153935768 Common - putative thiol-disulfide oxidoreductase ResA CLC_0322 153 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 153936489 Common - hypothetical protein CLC_1162 25 COG4866 COG4866, Uncharacterized conserved protein Function unknown 153937735 Pathogen - hypothetical protein CLC_1973 1 None None None 153937401 Common - radical SAM domain protein CLC_3558 93 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 153935430 Common - hypothetical protein CLC_0949 28 COG2320 GrpB, Uncharacterized conserved protein Function unknown 153935367 Pathogen - hypothetical protein CLC_0631 1 None None None 153935558 Common - FAD-binding protein CLC_0293 56 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153936753 Common rpsJ ribosomal protein S10 CLC_3426 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 153936681 Pathogen - hypothetical protein CLC_1845 1 None None None 153934947 Common - putative diguanylate cyclase CLC_0415 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 153935122 Common - hypothetical protein CLC_3532 1 None None None 153937093 Common fhuG ferrichrome ABC transporter, permease protein FhuG CLC_0742 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153937064 Common - putative cation transporting ATPase CLC_2867 191 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153937578 Common - cation-transporting ATPase, P-type CLC_1577 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153937671 Common - hypothetical protein CLC_1443 1 None None None 153937750 Common - DNA-binding response regulator, LuxR family CLC_1415 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153934876 Pathogen - hypothetical protein CLC_0445 1 None None None 153935205 Common ppdK pyruvate, phosphate dikinase CLC_2837 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 153936292 Common - DNA-binding response regulator CLC_0832 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937586 Common - vanZF protein CLC_2006 13 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 153936871 Common - DNA-binding protein CLC_3539 8 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 153936474 Common - response regulator CLC_1729 191 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153935354 Common - branched-chain amino acid transport system II carrier protein CLC_3236 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 153937520 Common - transcriptional regulator, TetR family CLC_0505 115 COG1309 AcrR, Transcriptional regulator Transcription 153936989 Common selB selenocysteine-specific translation elongation factor CLC_2872 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 153934744 Common - phosphoglycerate mutase family protein CLC_0815 13 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 153935043 Common murA-1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase CLC_0207 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 153936544 Common - carbon monoxide dehydrogenase CLC_1369 24 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 153934654 Common - transcriptional regulator, GntR family/aminotransferase, classes I and II CLC_1959 182 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153935478 Common - 5-formyltetrahydrofolate cyclo-ligase family protein CLC_2479 58 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 153936500 Common ldhA-1 D-lactate dehydrogenase CLC_3225 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 153936455 Pathogen - hypothetical protein CLC_2198 1 None None None 153936432 Common - hydrolase, alpha/beta fold family CLC_2041 110 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153936126 Common glxK glycerate kinase CLC_2157 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 153935077 Common - putative glucokinase CLC_1631 173 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 153936559 Common - PRC-barrel domain protein CLC_2257 12 COG1873 COG1873, Uncharacterized conserved protein Function unknown 153935750 Common jag jag protein CLC_3643 72 COG1847 Jag, Predicted RNA-binding protein General function prediction only 153936823 Common metG methionyl-tRNA synthetase CLC_0123 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937039 Common - putative ABC transporter, ATP-binding protein/permease protein CLC_0639 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153934860 Common dacB D-alanyl-D-alanine carboxypeptidase CLC_1796 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153937758 Common - ABC transporter, permease protein CLC_0722 46 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 153934788 Common - ABC transporter, ATP-binding protein CLC_3081 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153936137 Common cggR central glycolytic genes regulator CLC_0281 40 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153937595 Common - RNA modification enzyme, MiaB family CLC_2851 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 153936491 Common - class II aldolase, tagatose bisphosphate family CLC_1939 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 153937429 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase CLC_0491 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 153936416 Common - hypothetical protein CLC_2679 14 None None None 153937120 Common - ATPase, AAA family CLC_1056 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 153936068 Common - HAD-superfamily hydrolase, subfamily IIB CLC_2471 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 153935047 Common - oxidoreductase, FAD dependent CLC_0022 47 COG0579 COG0579, Predicted dehydrogenase General function prediction only 153937686 Common - glyoxalase family protein CLC_1578 4 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 153937201 Pathogen - hypothetical protein CLC_2907 1 None None None 153934683 Common - MATE efflux family protein CLC_0363 137 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153937798 Common - xanthine dehydrogenase family protein, FAD-binding subunit CLC_1324 101 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 153936960 Common - hypothetical protein CLC_2647 1 None None None 153936411 Common - hypothetical protein CLC_2888 40 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 153936994 Common - polar amino acid uptake family ABC transporter, PAAT family, ATP-binding protein CLC_0486 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153937431 Common - putative chitinase CLC_0785 41 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 153936235 Common add adenosine deaminase CLC_1043 115 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 153934902 Common - methyltransferase domain protein CLC_2582 4 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 153937069 Common cysK-1 cysteine synthase A CLC_0261 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 153935638 Common - putative ABC transporter, permease protein CLC_0642 33 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153936550 Common - iron-sulfur binding protein CLC_2144 40 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 153936324 Common cotJC spore coat peptide assembly protein CotJC CLC_1271 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 153936241 Common hypF [NiFe] hydrogenase maturation protein HypF CLC_1778 117 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 153935999 Common - putative polysaccharide transporter CLC_2996 77 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153937008 Common - putative nicotinate phosphoribosyltransferase CLC_1447 112 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 153935744 Common rimI ribosomal-protein-alanine acetyltransferase CLC_3267 192 COG0456 RimI, Acetyltransferases General function prediction only 153935341 Common - hypothetical protein CLC_3161 2 None None None 153934909 Pathogen - hypothetical protein CLC_0784 1 None None None 153935807 Common galE UDP-glucose 4-epimerase CLC_2653 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 153935449 Common - hypothetical protein CLC_1445 1 None None None 153937791 Common - manganese/zinc/iron chelate uptake ABC transporter, Mzt family, permease protein CLC_1397 193 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 153937494 Common - peptide ABC transporter, Pep4E family, ATP-binding protein CLC_0379 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153934731 Common - D-alanyl-D-alanine carboxypeptidase family protein CLC_0664 38 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153935649 Common - putative glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent CLC_1293 223 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153937501 Common - N-acetylmuramoyl-L-alanine amidase CLC_3387 174 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153937385 Pathogen - hypothetical protein CLC_1641 1 None None None 153936250 Common - metallo-beta-lactamase family protein CLC_1115 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 153937492 Common luxS autoinducer-2 production protein LuxS CLC_0781 56 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 153937266 Common - putative sodium extrusion ATP-binding protein NatA CLC_2161 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 153936646 Common - transcriptional regulator, LytR family CLC_0681 210 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937245 Common - DNA-binding response regulator CLC_3294 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936561 Common - putative methylcobalamin:Coenzyme M methyltransferase CLC_1531 24 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 153936061 Common - putative anaerobic ribonucleoside-triphosphate reductase activating protein CLC_1055 73 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 153935929 Common gpr spore protease CLC_2862 15 None None None 153936104 Common - pyruvate ferredoxin oxidoreductase CLC_2634 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 153937841 Common - PHP domain protein CLC_3565 36 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 153937146 Common - NlpC/P60 family protein CLC_0110 158 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 153936194 Common nusA N utilization substance protein A CLC_2268 223 COG0195 NusA, Transcription elongation factor Transcription 153937175 Common - transcriptional regulator, PadR family CLC_0496 52 COG1695 COG1695, Predicted transcriptional regulators Transcription 153934669 Common - hypothetical protein CLC_2953 2 None None None 153934483 Common - pentapeptide repeat family protein CLC_0905 44 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 153937659 Common pyrB aspartate carbamoyltransferase CLC_3152 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 153935148 Common - hypothetical protein CLC_0534 36 COG3610 COG3610, Uncharacterized conserved protein Function unknown 153935305 Common - hypothetical protein CLC_0900 1 None None None 153937016 Common dnaK chaperone protein DnaK CLC_2855 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 153936312 Common prdA D-proline reductase, PrdA proprotein CLC_2331 8 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153935727 Common - MATE efflux family protein CLC_2069 77 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153935955 Common - glycerol uptake facilitator protein CLC_2661 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 153934759 Pathogen - hypothetical protein CLC_0633 1 None None None 153935815 Common - PTS system, fructose family, IIBC component CLC_1937 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 153935643 Common - NAD-dependent epimerase/dehydratase family protein CLC_2552 234 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 153934790 Common - peptide ABC transporter, Pep4E family, permease protein CLC_1434 9 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153936586 Common - ATP-dependent protease CLC_3620 239 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 153934720 Common - hypothetical protein CLC_0023 12 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 153937479 Common - metallo-beta-lactamase family protein CLC_0515 20 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153937654 Common - acetyltransferase, GNAT family CLC_0676 19 COG0456 RimI, Acetyltransferases General function prediction only 153936976 Common - PemK family protein CLC_0459 34 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 153934956 Common - hypothetical protein CLC_2475 2 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153936369 Common - hypothetical protein CLC_2194 45 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153935625 Common - hypothetical protein CLC_0892 2 None None None 153937473 Common - transcriptional regulator, RpiR family CLC_1380 114 COG1737 RpiR, Transcriptional regulators Transcription 153935085 Common - glycosyl hydrolase, family 18 CLC_1253 81 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 153936307 Common - BRCT domain protein CLC_3096 109 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 153937000 Common - capsular exopolysaccharide family protein CLC_2560 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153937072 Common - putative electron transport protein CLC_2315 175 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 153935527 Common - putative ABC transporter, ATP-binding protein/permease protein CLC_0673 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153934757 Common rnpA ribonuclease P protein component CLC_3646 25 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 153936617 Common - HD domain protein CLC_1150 37 None None None 153934724 Common murC UDP-N-acetylmuramate--alanine ligase CLC_3526 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 153936376 Common - N-acetylmuramoyl-L-alanine amidase CLC_1461 24 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153935549 Common - metallo-beta-lactamase family protein CLC_1148 124 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 153935403 Common - glycerophosphoryl diester phosphodiesterase family protein CLC_3122 175 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 153934825 Common - ethanolamine utilization protein EutJ family protein CLC_2055 183 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 153934813 Common - hypothetical protein CLC_2330 2 None None None 153936962 Common - CAAX amino terminal protease family protein CLC_0464 54 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 153937250 Common - hypothetical protein CLC_0541 5 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 153936299 Common - hypothetical protein CLC_1566 29 COG5441 COG5441, Uncharacterized conserved protein Function unknown 153936013 Common flgE flagellar hook protein flgE CLC_2529 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 153936262 Common - ABC transporter, ATP-binding/permease protein CLC_1876 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153937862 Common - transcriptional regulator, AraC family CLC_2023 118 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153935151 Common - BioY family protein CLC_2184 76 COG1268 BioY, Uncharacterized conserved protein General function prediction only 153936522 Common cysE serine O-acetyltransferase CLC_0262 216 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 153935920 Common - conserved hypothetical protein TIGR00268 CLC_1226 73 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 153936656 Pathogen - hypothetical protein CLC_2195 1 None None None 153935895 Pathogen - putative lipoprotein CLC_1064 1 None None None 153936097 Common - PTS system, beta-glucoside-specific, IIABC component CLC_0934 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153934528 Common folD methylenetetrahydrofolate dehydrogenase CLC_1215 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 153937338 Common - metallo-beta-lactamase family protein CLC_0481 119 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 153935838 Common - putative deoxyribonucleoside regulator CLC_1593 70 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153935008 Pathogen - hypothetical protein CLC_2555 1 None None None 153937462 Common - flagellin CLC_2604 117 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153935468 Pathogen - hypothetical protein CLC_3162 1 None None None 153934675 Common - glycosyl transferase, group 1 family protein CLC_0161 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153937231 Common - glycosyl hydrolase, family 1 CLC_0935 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 153937552 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 CLC_2596 50 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 153936398 Common - collagenase CLC_1647 39 COG3291 COG3291, FOG: PKD repeat General function prediction only 153936748 Common - DNA-binding response regulator CLC_2212 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935899 Common - glycosyl hydrolase, family 4 CLC_3305 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 153937259 Common - hypothetical protein CLC_3636 13 None None None 153935293 Common - putative alginate O-acetyltransferase AlgI CLC_2948 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 153937079 Common truB tRNA pseudouridine synthase B CLC_2262 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 153935228 Pathogen - hypothetical protein CLC_0714 1 None None None 153937469 Common - Na+/H+ antiporter family protein CLC_3347 79 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 153935309 Common - putative spore coat protein CLC_0160 5 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 153934590 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase CLC_2775 167 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 153936865 Common aspS-2 aspartyl-tRNA synthetase CLC_2956 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937452 Common - hypothetical protein CLC_2652 3 None None None 153936046 Pathogen - hypothetical protein CLC_2777 1 None None None 153935771 Common - hypothetical protein CLC_2925 2 None None None 153937852 Pathogen - hypothetical protein CLC_2064 1 None None None 153937781 Common - sodium:dicarboxylate symporter family protein CLC_3351 133 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 153935691 Common - hypothetical protein CLC_2080 2 None None None 153936352 Common - hypothetical protein CLC_1605 5 COG2391 COG2391, Predicted transporter component General function prediction only 153936768 Common - sodium:alanine symporter family protein CLC_1609 34 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153936806 Common sbp small basic protein CLC_1500 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 153934886 Pathogen - hypothetical protein CLC_1915 1 None None None 153937602 Common - DNA-cytosine methyltransferase family protein CLC_2744 121 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 153934495 Common - prenyltransferase, UbiA family CLC_2248 63 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 153936715 Common rodA-1 rod shape-determining protein RodA CLC_0670 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 153936443 Common coaD pantetheine-phosphate adenylyltransferase CLC_2348 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 153935835 Common - transcriptional regulator, PadR family CLC_1040 18 COG1695 COG1695, Predicted transcriptional regulators Transcription 153937141 Common - hypothetical protein CLC_0149 82 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 153936604 Common ruvA Holliday junction DNA helicase RuvA CLC_2973 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 153935788 Common - hypothetical protein CLC_1338 7 None None None 153935250 Common - hypothetical protein CLC_1166 49 COG2431 COG2431, Predicted membrane protein Function unknown 153935698 Common - hypothetical protein CLC_2491 1 None None None 153936327 Common spoIVA stage IV sporulation protein A CLC_2374 15 None None None 153935327 Common - putative DNA replication protein CLC_2940 42 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 153936931 Common - hypothetical protein CLC_0405 6 None None None 153937634 Common - hypothetical protein CLC_3509 3 None None None 153936288 Common - transglycosylase SLT domain protein CLC_2909 173 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153936054 Common rpsN ribosomal protein S14 CLC_3412 188 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 153935364 Common - sensor histidine kinase CLC_1230 27 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 153935977 Common - electron transfer flavoprotein, beta subunit/FixA family protein CLC_3229 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 153936801 Common gyrB DNA gyrase, B subunit CLC_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 153935317 Common - putative lipoprotein CLC_0660 1 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 153935358 Common arsA arsenical pump-driving ATPase ArsA CLC_0812 98 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 153934710 Common - hypothetical protein CLC_3354 3 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 153936163 Common - methyl-accepting chemotaxis protein CLC_0512 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153934470 Common - HD domain protein CLC_3325 44 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 153935094 Common - acetyltransferase, GNAT family CLC_1039 7 COG0456 RimI, Acetyltransferases General function prediction only 153934938 Common - xanthine dehydrogenase family protein, molybdopterin-binding subunit CLC_2778 123 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 153936536 Pathogen - hypothetical protein CLC_2866 1 None None None 153936028 Common - RNA methyltransferase, TrmH family CLC_3035 211 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 153935454 Pathogen - hypothetical protein CLC_0440 1 COG4980 GvpP, Gas vesicle protein General function prediction only 153935878 Pathogen - hypothetical protein CLC_2412 1 None None None 153936272 Common - non-haem haloperoxidase family protein CLC_0894 135 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153936058 Common - transcriptional regulator, MerR family CLC_2110 6 COG0789 SoxR, Predicted transcriptional regulators Transcription 153937353 Common pepQ proline dipeptidase CLC_1976 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153936786 Common - oligopeptide/dipeptide ABC transporter, ATP-binding protein CLC_3057 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153934963 Common - hypothetical protein CLC_2074 13 None None None 153934920 Common sbcC exonuclease SbcC CLC_0547 143 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 153937556 Common - heavy metal-associated domain protein CLC_1091 79 COG2836 COG2836, Uncharacterized conserved protein Function unknown 153936415 Common - CAAX amino terminal protease family protein CLC_0627 2 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 153937115 Pathogen - hypothetical protein CLC_0770 1 None None None 153935006 Common cadD cadmium resistance transporter CadD CLC_0895 17 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 153935665 Common - hypothetical protein CLC_1080 7 None None None 153935547 Common - ornithine cyclodeaminase family protein CLC_2447 98 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 153935985 Common - MutT/nudix family protein CLC_2706 153 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153935440 Common - metallo-beta-lactamase family protein CLC_0595 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 153936775 Common trmU-1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CLC_1228 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 153935238 Common - hypothetical protein CLC_0586 2 None None None 153936907 Common cls cardiolipin synthetase CLC_2547 152 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 153937636 Common - hypothetical protein CLC_0129 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 153936190 Pathogen - putative transposase, OrfA CLC_0856 2 None None None 153935332 Common - UDP-N-acetylglucosamine 2-epimerase CLC_3002 152 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 153936350 Common - hypothetical protein CLC_1814 1 None None None 153937225 Common - conserved hypothetical protein TIGR00150 CLC_3265 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 153937613 Common - RibD domain protein CLC_0313 66 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 153937771 Common - hypothetical protein CLC_3262 4 COG4025 COG4025, Predicted membrane protein Function unknown 153934706 Common - hypothetical protein CLC_0694 2 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 153935508 Common - hypothetical protein CLC_0108 71 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 153934524 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_1237 20 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153937012 Common panE 2-dehydropantoate 2-reductase CLC_1213 125 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 153936277 Common gidA-2 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CLC_3641 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 153935272 Common - ABC transporter, permease protein CLC_1896 21 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 153937524 Common - hypothetical protein CLC_2587 37 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 153936142 Common - aluminum resistance protein CLC_1738 30 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 153937365 Common - sensory box sigma-54 dependent transcriptional regulator CLC_1672 180 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 153936637 Common fusA-1 translation elongation factor G CLC_3428 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 153935038 Common - acetyltransferase, GNAT family CLC_3074 86 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153937026 Common - hypothetical protein CLC_2806 25 COG0011 COG0011, Uncharacterized conserved protein Function unknown 153934792 Common npr-6 thermolysin metallopeptidase CLC_1483 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 153936039 Common - putative thiol peroxidase CLC_0575 125 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 153936238 Common relA GTP pyrophosphokinase CLC_2961 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 153935297 Common gatB glutamyl-tRNA(Gln) amidotransferase, B subunit CLC_3208 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 153936632 Common - hypothetical protein CLC_2081 4 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 153934893 Common - hypothetical protein CLC_2743 2 None None None 153937753 Common - methyl-accepting chemotaxis protein CLC_1760 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153935323 Common - iron chelate uptake ABC transporter, FeCT family, solute-binding protein CLC_0360 75 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153935689 Common - putative phage head-tail adaptor CLC_3535 1 None None None 153937837 Common copZ copper chaperone CopZ CLC_1343 39 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153937169 Common trmE tRNA modification GTPase TrmE CLC_3642 224 COG0486 ThdF, Predicted GTPase General function prediction only 153935310 Common - helix-turn-helix domain protein CLC_0679 112 COG1396 HipB, Predicted transcriptional regulators Transcription 153937643 Common pyrR-2 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase CLC_2697 132 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 153937869 Common - putative 2-oxoacid:acceptor oxidoreductase, delta subunit CLC_3368 50 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 153935567 Common lctP L-lactate permease CLC_1058 105 COG1620 LldP, L-lactate permease Energy production and conversion 153935382 Common - putative accessory gene regulator protein B CLC_0396 9 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 153934519 Common - DHH family protein CLC_2263 81 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 153937825 Common - flagellar biosynthetic protein FliR/FlhB CLC_2521 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 153934539 Common - hypothetical protein CLC_3032 32 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 153935539 Pathogen - hypothetical protein CLC_2569 1 None None None 153936878 Pathogen - hypothetical protein CLC_0623 1 None None None 153937358 Common cmr3 CRISPR-associated protein, Cmr3 family CLC_2116 3 COG1769 COG1769, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 153936512 Pathogen - hypothetical protein CLC_1893 1 None None None 153937282 Common - TPR domain protein CLC_3017 14 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 153936111 Common - hypothetical protein CLC_3402 5 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 153936526 Common - cytosine permease CLC_2016 70 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 153937297 Common - hypothetical protein CLC_1678 6 None None None 153934692 Common - uroporphyrinogen decarboxylase family protein CLC_2166 35 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 153934787 Common - hypothetical protein CLC_2917 11 None None None 153936774 Common - hypothetical protein CLC_0717 2 None None None 153936345 Common - aldolase, class II, AraD/FucA subfamily CLC_1308 171 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 153936481 Common - rubredoxin CLC_2981 123 COG1773 COG1773, Rubredoxin Energy production and conversion 153936847 Common - peptidil-prolyl isomerase family protein CLC_0088 152 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 153937806 Common - hypothetical protein CLC_2968 1 None None None 153937480 Common - hypothetical protein CLC_3087 15 COG4708 COG4708, Predicted membrane protein Function unknown 153936226 Common - glycosyl hydrolase, family 13 CLC_1632 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 153935942 Common - DedA family protein CLC_0414 101 COG0398 COG0398, Uncharacterized conserved protein Function unknown 153937190 Common enr 2-enoate reductase CLC_2109 234 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 153935712 Common tsf translation elongation factor Ts CLC_2282 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 153934916 Common - ABC transporter, ATP-binding protein CLC_1022 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153934761 Common aroK shikimate kinase CLC_1843 193 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 153937818 Pathogen - hypothetical protein CLC_1854 1 None None None 153936322 Pathogen - hypothetical protein CLC_2123 1 None None None 153935410 Common - putative internalin CLC_1902 25 None None None 153936703 Common prfA peptide chain release factor 1 CLC_0187 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 153935415 Common - putative iron chelate uptake ABC transporter, solute-binding protein CLC_1028 78 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153937427 Common - transcriptional regulator, Crp/Fnr family CLC_1011 162 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153937714 Common - bacterial extracellular solute-binding protein CLC_3131 8 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153935874 Common - hypothetical protein CLC_0237 15 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 153937156 Common gltX glutamyl-tRNA synthetase CLC_1146 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 153937394 Common - acetyltransferase, GNAT family CLC_0921 48 COG0456 RimI, Acetyltransferases General function prediction only 153935990 Common - flagellin CLC_2541 112 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153934634 Common - DNA-binding response regulator, LytTr family CLC_3250 213 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 153935530 Pathogen - hypothetical protein CLC_2301 1 None None None 153936687 Common selD selenide, water dikinase, selenocysteine-containing CLC_2874 132 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 153935419 Common purF-1 amidophosphoribosyltransferase CLC_2774 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 153937777 Pathogen - hypothetical protein CLC_3029 1 None None None 153934780 Common rplD ribosomal protein L4 CLC_3424 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 153937019 Pathogen - hypothetical protein CLC_0702 1 None None None 153937183 Common deoC deoxyribose-phosphate aldolase CLC_1594 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 153935656 Common - tetratricopeptide repeat protein CLC_3384 49 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 153937748 Common - hypothetical protein CLC_0106 2 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153937620 Common - ABC transporter, ATP-binding protein CLC_2009 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937197 Common - penicillin-binding protein CLC_3326 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 153936887 Common - hypothetical protein CLC_1964 28 COG3875 COG3875, Uncharacterized conserved protein Function unknown 153936220 Common - hypothetical protein CLC_2701 8 None None None 153935949 Common - ABC transporter, permease protein CLC_2664 1 None None None 153937848 Common - hypothetical protein CLC_2581 15 None None None 153936943 Pathogen - hypothetical protein CLC_1288 1 None None None 153935873 Common - endonuclease/exonuclease/phosphatase family protein CLC_1804 11 None None None 153936593 Common - putative rubrerythrin CLC_0696 8 COG1633 COG1633, Uncharacterized conserved protein Function unknown 153934853 Common - acetyltransferase, GNAT family CLC_1767 29 COG0456 RimI, Acetyltransferases General function prediction only 153937062 Common - carboxyl-terminal protease CLC_3332 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 153935933 Common - sodium:solute symporter family protein CLC_3563 37 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 153937767 Common - bacterial extracellular solute-binding protein, family 5 CLC_3207 115 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153934614 Common - hypothetical protein CLC_1046 2 None None None 153935033 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CLC_2252 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 153934923 Common - putative amidohydrolase CLC_0867 70 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 153936729 Common hisC histidinol-phosphate aminotransferase CLC_1602 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 153936214 Common - hypothetical protein CLC_2819 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 153934595 Common - NAD-dependent epimerase/dehydratase family protein CLC_2043 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 153936381 Common - putative ABC transporter, ATP-binding/permease protein CLC_1898 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153937606 Common pfkA 6-phosphofructokinase CLC_3316 155 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 153937441 Common - HAD hydrolase, IIB family CLC_1216 121 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 153936357 Common - hydrolase, alpha/beta fold family CLC_0579 84 COG2267 PldB, Lysophospholipase Lipid metabolism 153935881 Pathogen - hypothetical protein CLC_0637 1 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 153937842 Common hisS histidyl-tRNA synthetase CLC_2957 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937273 Common - restriction endonuclease family protein CLC_1304 18 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 153934775 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CLC_3321 209 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 153934648 Common - hypothetical protein CLC_0395 3 None None None 153936556 Common - flagellin CLC_2605 116 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153935634 Common - transcriptional regulator, LacI family CLC_1630 129 COG1609 PurR, Transcriptional regulators Transcription 153936295 Pathogen - hypothetical protein CLC_0166 1 None None None 153936463 Common - hypothetical protein CLC_0422 4 None None None 153934840 Pathogen - hypothetical protein CLC_0253 1 None None None 153935037 Common - thiolase CLC_3110 188 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 153935197 Common - putative cell envelope-related function transcriptional attenuator CLC_2879 65 COG1316 LytR, Transcriptional regulator Transcription 153935578 Common - hypothetical protein CLC_2432 9 None None None 153935611 Common - ComEC/Rec2 family protein CLC_2865 91 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 153935573 Common fldI R-phenyllactate dehydratase activator CLC_3233 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 153935916 Common - glycerophosphoryl diester phosphodiesterase family protein CLC_1233 139 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 153936201 Pathogen - hypothetical protein CLC_2739 1 None None None 153937541 Common - hypothetical protein CLC_0758 1 None None None 153937162 Common - cobalt transport permease, CbiQ family CLC_3392 77 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 153936175 Common - hypothetical protein CLC_1637 51 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 153935962 Pathogen ntnH botulinum neurotoxin type A1, nontoxic-nonhemagglutinin component, NTNH CLC_0861 1 None None None 153937707 Common - lipoprotein, NLPA family CLC_1535 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 153936840 Common grdB glycine reductase, selenoprotein B CLC_1297 12 None None None 153935188 Common pyrI aspartate carbamoyltransferase, regulatory subunit CLC_3151 65 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 153937697 Common rplI ribosomal protein L9 CLC_3621 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 153935480 Common - hypothetical protein CLC_0787 1 None None None 153937348 Common - hypothetical protein CLC_0462 7 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153935756 Common - peptide/opine/nickel uptake ABC transporter, PepT family, permease protein CLC_1393 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936621 Common - putative protein-glutamine gamma-glutamyltransferase CLC_2219 3 None None None 153935709 Common - hypothetical protein CLC_1620 8 None None None 153935591 Common - hypothetical protein CLC_1466 1 None None None 153935421 Common sdhA L-serine dehydratase, iron-sulfur-dependent, alpha subunit CLC_1256 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 153935867 Pathogen - hypothetical protein CLC_2574 3 None None None 153935444 Pathogen - hypothetical protein CLC_1556 1 None None None 153937487 Common - putative lipoprotein CLC_1291 7 None None None 153935266 Common - hypothetical protein CLC_1057 3 None None None 153937567 Common gutM glucitol operon activator protein CLC_3362 16 COG4578 GutM, Glucitol operon activator Transcription 153935492 Common - glycosyl transferase, group 1 family protein CLC_2576 76 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153936917 Common - hypothetical protein CLC_0413 29 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 153934869 Common cdsA phosphatidate cytidylyltransferase CLC_2277 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 153937137 Common - hypothetical protein CLC_2464 19 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 153934769 Common - hypothetical protein CLC_3271 15 COG4720 COG4720, Predicted membrane protein Function unknown 153934510 Common rho transcription termination factor Rho CLC_0182 203 COG1158 Rho, Transcription termination factor Transcription 153935849 Common - DNA binding protein, excisionase family CLC_2075 6 None None None 153936833 Common sigG RNA polymerase sigma-G factor CLC_2390 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 153936336 Common mtnK 5-methylthioribose kinase CLC_1305 27 COG4857 COG4857, Predicted kinase General function prediction only 153936010 Common - hypothetical protein CLC_2583 4 None None None 153937834 Common - putative ATP-dependent DNA helicase PcrA CLC_1451 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153936064 Common - hypothetical protein CLC_1986 4 None None None 153935840 Common ligA DNA ligase, NAD-dependent CLC_3213 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 153936199 Common - putative ATP-binding protein CLC_3270 17 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 153936896 Pathogen - hypothetical protein CLC_2738 2 None None None 153935173 Common - antibiotic ABC transporter, permease protein CLC_1613 5 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 153935790 Common - oxidoreductase, NAD/FAD-binding CLC_1670 88 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153934563 Pathogen - hypothetical protein CLC_1032 1 None None None 153935592 Common - transcriptional regulator, AraC family CLC_0364 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153937073 Common rpsS ribosomal protein S19 CLC_3421 241 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 153936019 Common - manganese/zinc/iron chelate uptake ABC transporter, Mzt family, ATP-binding protein CLC_1398 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 153935853 Common - spore germination protein CLC_1923 10 None None None 153934807 Common - leucine rich repeat protein CLC_1725 32 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 153936714 Common - GTP-binding protein CLC_2378 238 COG1160 COG1160, Predicted GTPases General function prediction only 153935487 Common - hypothetical protein CLC_0268 36 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 153935168 Common - iron-sulfur cluster-binding protein CLC_1379 69 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 153936306 Common - methyl-accepting chemotaxis protein CLC_3538 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153935226 Common - ABC transporter, permease protein CLC_1159 154 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 153935953 Common - transcriptional regulator, AraC family CLC_0359 98 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153934566 Common - chromate transporter protein CLC_0457 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 153935798 Common trmD tRNA (guanine-N1)-methyltransferase CLC_2293 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 153936664 Common prdD PrdD protein CLC_2328 2 None None None 153937665 Common rhlE ATP-dependent RNA helicase RhlE CLC_0695 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153936158 Pathogen - hypothetical protein CLC_2030 1 None None None 153936722 Common hsp90 heat shock protein CLC_1931 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 153934478 Common - D-isomer specific 2-hydroxyacid dehydrogenase CLC_3571 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 153937047 Common ksgA dimethyladenosine transferase CLC_0128 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 153937795 Common - DNA-binding response regulator CLC_1914 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935190 Common - V-type ATPase, D subunit CLC_2496 44 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 153935195 Common topA DNA topoisomerase I CLC_2285 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 153937538 Common - putative helicase CLC_3286 75 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 153935286 Common - hypothetical protein CLC_2748 1 None None None 153935345 Common - hypothetical protein CLC_0941 20 None None None 153934545 Common - iron-sulfur cluster-binding protein CLC_0059 25 COG0716 FldA, Flavodoxins Energy production and conversion 153936418 Common - amino acid permease family protein CLC_2169 53 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153934604 Common - glucose-1-phosphate cytidylyltransferase CLC_2592 172 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 153937571 Common feoB-3 ferrous iron transport protein B CLC_1129 164 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 153937481 Common - hypothetical protein CLC_3557 14 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 153934980 Common - putative scdA protein CLC_0712 39 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 153937559 Common - auxin efflux carrier family protein CLC_2444 156 COG0679 COG0679, Predicted permeases General function prediction only 153936203 Pathogen - hypothetical protein CLC_0776 1 None None None 153936077 Common - hypothetical protein CLC_2086 3 None None None 153935135 Pathogen - hypothetical protein CLC_2413 1 None None None 153936181 Common - putative lipoprotein CLC_0131 1 None None None 153934619 Common pyc pyruvate carboxylase CLC_3254 242 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 153936387 Common - putative undecaprenol kinase CLC_0470 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 153937729 Pathogen - hypothetical protein CLC_2337 1 None None None 153935061 Common - multicopper oxidase family protein CLC_0942 74 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 153937423 Common mnaA UDP-N-acetylglucosamine 2-epimerase CLC_0196 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 153936557 Common - D-alanyl-D-alanine carboxypeptidase family protein CLC_1441 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153934746 Pathogen - hypothetical protein CLC_0041 1 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 153936831 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase CLC_2589 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 153937615 Common - RelA/SpoT domain protein CLC_0238 49 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 153935851 Common - putative prolyl-tRNA synthetase CLC_3452 213 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153936034 Common dnaJ chaperone protein DnaJ CLC_2854 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 153937655 Pathogen - hypothetical protein CLC_1786 1 None None None 153936493 Common - DNA-binding response regulator CLC_1105 114 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 153936393 Common - hypothetical protein CLC_1583 98 COG2378 COG2378, Predicted transcriptional regulator Transcription 153936384 Common eno enolase CLC_0286 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 153935352 Common uvrB excinuclease ABC, B subunit CLC_3330 235 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 153936987 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CLC_1957 242 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153935501 Common obg Spo0B-associated GTP-binding protein CLC_2883 249 COG0536 Obg, Predicted GTPase General function prediction only 153936300 Common - hypothetical protein CLC_1653 3 None None None 153935343 Common flhA flagellar biosynthesis protein FlhA CLC_2520 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 153935359 Common - putative CoA-substrate-specific enzyme activase CLC_1179 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 153936932 Common - hypothetical protein CLC_1172 1 None None None 153937788 Common - amino acid permease family protein CLC_0453 194 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153934735 Common - hypothetical protein CLC_1386 11 None None None 153934973 Common - cephalosporin hydroxylase family protein CLC_2586 20 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 153936580 Common - rrF2 family protein CLC_2441 179 COG1959 COG1959, Predicted transcriptional regulator Transcription 153936243 Common hsp33 33 kDa chaperonin CLC_3053 134 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 153934749 Common - hypothetical protein CLC_2656 3 COG4889 COG4889, Predicted helicase General function prediction only 153935821 Common - putative pyrazinamidase/nicotinamidase CLC_1183 77 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153935087 Common - PSP1 domain protein CLC_0105 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 153936602 Common - TPR domain protein CLC_1156 1 None None None 153936992 Common - tetratricopeptide repeat family protein CLC_1187 121 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 153937796 Common asp alkaline shock protein CLC_1831 41 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 153934684 Pathogen - hypothetical protein CLC_3135 1 None None None 153937006 Common - UBA/TS-N domain protein CLC_2237 5 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 153935809 Common - ABC transporter, ATP-binding/permease protein CLC_1899 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153935252 Common - hypothetical protein CLC_1269 1 None None None 153934733 Common - HDIG domain protein CLC_1574 64 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 153935115 Pathogen - hypothetical protein CLC_2593 2 None None None 153934549 Common - hypothetical protein CLC_0080 3 None None None 153935882 Pathogen - hypothetical protein CLC_0796 1 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153935424 Common - hypothetical protein CLC_0985 54 COG0789 SoxR, Predicted transcriptional regulators Transcription 153937625 Common asnA aspartate--ammonia ligase CLC_1538 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 153935604 Common - DNA-binding protein CLC_2401 31 COG1476 COG1476, Predicted transcriptional regulators Transcription 153937871 Common pepD-1 aminoacyl-histidine dipeptidase CLC_1423 55 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 153934995 Common - hypothetical protein CLC_0303 1 None None None 153935746 Common - hypothetical protein CLC_0878 6 None None None 153935766 Common rplW ribosomal protein L23 CLC_3423 211 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 153934755 Common - hypothetical protein CLC_1501 21 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 153937108 Pathogen - hypothetical protein CLC_0625 1 None None None 153937519 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_1752 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 153934921 Common - hypothetical protein CLC_0844 20 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 153937085 Common secF protein-export membrane protein SecF CLC_2964 214 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 153936856 Common ribH 6,7-dimethyl-8-ribityllumazine synthase CLC_2762 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 153937466 Common - RNA polymerase sigma-70 factor family CLC_0793 22 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153935103 Pathogen - hypothetical protein CLC_2376 1 None None None 153934802 Common - hypothetical protein CLC_3157 10 None None None 153936003 Pathogen - hypothetical protein CLC_1165 1 None None None 153936854 Common - putative RNA polymerase sigma factor CLC_1645 21 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153936315 Common rpmB ribosomal protein L28 CLC_2353 57 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 153934945 Common - hypothetical protein CLC_0990 41 COG2320 GrpB, Uncharacterized conserved protein Function unknown 153935609 Common - hypothetical protein CLC_3610 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 153937243 Common - sodium:dicarboxylate symporter family protein CLC_1907 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 153937417 Pathogen - hypothetical protein CLC_1573 1 None None None 153935040 Common - hypothetical protein CLC_1189 1 None None None 153934626 Common - putative hydroxyacyl-CoA:R-2-hydroxyglutaryl-CoA transferase CLC_2142 114 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 153935431 Pathogen - hypothetical protein CLC_2932 1 None None None 153936405 Common - ABC transporter, ATP-binding protein CLC_2812 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153936860 Common - DNA-binding protein CLC_2402 49 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 153937218 Common - putative DNA replication protein DnaD CLC_3586 11 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 153936085 Common - putative sugar ABC transporter, permease protein CLC_0277 132 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 153937302 Common - penicillin-binding protein CLC_2424 197 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 153935203 Common - transcriptional regulator, GntR family CLC_1360 110 COG1725 COG1725, Predicted transcriptional regulators Transcription 153934579 Common - DNA-binding response regulator CLC_0661 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153934773 Pathogen - hypothetical protein CLC_2281 1 None None None 153937318 Common rpmI ribosomal protein L35 CLC_3039 201 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 153935680 Common - putative branched-chain amino acid aminotransferase CLC_2630 166 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 153935408 Common - hypothetical protein CLC_0233 95 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 153937464 Common - hypothetical protein CLC_2174 4 None None None 153937403 Common hisK histidinol-phosphatase CLC_2443 27 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 153937584 Common - DNA repair protein, RadC family CLC_2900 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 153936487 Common - polysaccharide deacetylase family protein CLC_2651 90 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153935405 Common - putative transcriptional regulator CLC_0816 16 COG1309 AcrR, Transcriptional regulator Transcription 153936000 Common mtnA S-methyl-5-thioribose-1-phosphate isomerase CLC_1306 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 153937774 Common - hypothetical protein CLC_0838 6 None None None 153936881 Common - subtilase family protein CLC_3569 50 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 153937355 Common - hypothetical protein CLC_2627 36 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 153936578 Common - putative ABC transporter, permease protein CLC_0617 2 None None None 153935858 Common rplA ribosomal protein L1 CLC_3436 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 153935004 Common - PP-loop family protein CLC_0399 164 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153937095 Common - hypothetical protein CLC_0231 21 COG3601 COG3601, Predicted membrane protein Function unknown 153936706 Common - putative lipoprotein CLC_0412 6 None None None 153935520 Common moeA molybdopterin biosynthesis enzyme MoeA CLC_1887 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 153935398 Common - hypothetical protein CLC_1458 1 None None None 153935860 Common cas6 CRISPR-associated protein Cas6 CLC_2121 7 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 153937101 Pathogen - hypothetical protein CLC_2827 1 None None None 153935514 Common - putative pilin CLC_1851 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 153935832 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CLC_0885 198 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 153937252 Common rplJ ribosomal protein L10 CLC_3435 213 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 153936808 Common - transcriptional regulator, AraC family CLC_0757 39 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 153937860 Common - cation efflux family protein CLC_3284 206 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 153936699 Common - putative phage infection protein CLC_1044 31 COG1511 COG1511, Predicted membrane protein Function unknown 153936434 Common - sensor histidine kinase CLC_0355 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936788 Common feoA-2 ferrous ion transport protein A CLC_1130 50 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 153937311 Common - bacterial sugar transferase family protein CLC_2995 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 153934833 Common ogt methylated-DNA-[protein]-cysteine S-methyltransferase CLC_1564 220 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 153936740 Common - drug resistance transporter, EmrB/QacA family CLC_0698 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153935257 Common - [Fe] hydrogenase CLC_1790 184 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 153937280 Common - putative transketolase, N-terminal subunit CLC_3338 222 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 153937237 Common - transcriptional regulator, AraC family CLC_2040 137 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153935380 Common cheC chemotaxis protein CheC CLC_2621 48 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 153935922 Common - putative R-2-hydroxyglutaryl-CoA dehydratase subunit CLC_3155 39 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153937320 Common - amidohydrolase family protein CLC_1140 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153936654 Common pyrD dihydroorotate oxidase CLC_3147 223 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 153934526 Common - putative L-iditol 2-dehydrogenase CLC_3363 216 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153935773 Common - transcriptional regulator, GntR family CLC_0930 167 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153936048 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase CLC_2273 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 153936680 Common - O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein CLC_1820 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 153937514 Pathogen - hypothetical protein CLC_0593 1 None None None 153935631 Common thyA thymidylate synthase CLC_0824 98 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 153934815 Common - hypothetical protein CLC_0444 21 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153937017 Common arsD arsenical resistence operon repressor ArsD CLC_0811 31 None None None 153936815 Common - KWG leptospira repeat protein CLC_1052 29 None None None 153935897 Common - LD-carboxypeptidase family protein CLC_0096 86 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 153937607 Common brnQ-1 branched-chain amino acid transport system II carrier protein CLC_0868 51 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 153936507 Common - metallo-beta-lactamase family protein/flavodoxin CLC_1178 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 153936567 Common - putative phage shock protein CLC_1184 149 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153937459 Common cheR chemotaxis protein methyltransferase CheR CLC_2623 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 153937854 Common - hypothetical protein CLC_2930 27 COG5412 COG5412, Phage-related protein Function unknown 153934592 Common - acyl-CoA dehydrogenase family protein CLC_2139 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153937058 Common - putative threonyl-tRNA synthetase/uridine kinase CLC_0252 96 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 153934673 Common - formate/nitrite transporter family protein CLC_1012 100 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 153937722 Common - sensory box sigma-54 dependent transcriptional regulator CLC_1668 179 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 153935025 Common - ABC transporter, ATP-binding protein CLC_0830 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153936762 Common ceo N(5)-(carboxyethyl)ornithine synthase CLC_0588 119 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 153935584 Common - hypothetical protein CLC_1655 12 None None None 153936571 Common - sigma-E factor regulator, RseC/MucC family CLC_2955 8 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 153934497 Common - xanthine dehydrogenase family protein, iron-sulfur-binding subunit CLC_0319 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 153935786 Common - hypothetical protein CLC_2187 6 None None None 153935693 Common cbiK anaerobic sirohydrochlorin cobaltochelatase CLC_1008 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 153937783 Common - DNA-binding protein CLC_2943 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 153935096 Common - hypothetical protein CLC_1112 10 COG4129 COG4129, Predicted membrane protein Function unknown 153935612 Common rplO ribosomal protein L15 CLC_3406 215 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 153935307 Common - lipase/acylhydrolase, GDSL family CLC_2796 82 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 153934708 Common frr ribosome recycling factor CLC_2279 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 153936166 Pathogen - hypothetical protein CLC_1487 1 COG2234 Iap, Predicted aminopeptidases General function prediction only 153936445 Common - hypothetical protein CLC_1201 3 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 153936692 Common asdA aspartate 4-decarboxylase CLC_1209 118 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153936867 Common - transcriptional antiterminator, BglG family CLC_0707 29 COG3711 BglG, Transcriptional antiterminator Transcription 153934502 Common - ferritin family protein CLC_1727 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 153935997 Common - methyl-accepting chemotaxis protein CLC_0436 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153937410 Common - hypothetical protein CLC_2077 23 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 153935828 Common - thioredoxin family protein CLC_1762 158 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 153936310 Common - SCP-like extracellular protein CLC_1958 83 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 153936377 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CLC_1494 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 153937383 Common - exopolysaccharide biosynthesis protein CLC_2557 14 None None None 153936423 Common - hypothetical protein CLC_1272 24 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 153936102 Common - hypothetical protein CLC_3005 4 None None None 153935654 Common - hypothetical protein CLC_1318 1 None None None 153936309 Common fliP flagellar biosynthetic protein FliP CLC_2523 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 153935817 Common - zinc carboxypeptidase family protein CLC_1409 49 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 153934698 Common - RNA pseudouridine synthase family protein CLC_3216 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 153934581 Common cheB protein-glutamate methylesterase CheB CLC_2624 222 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 153937708 Common - oxidoreductase family protein CLC_1951 176 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153936587 Pathogen - hypothetical protein CLC_0555 1 None None None 153936728 Pathogen - hypothetical protein CLC_2936 1 None None None 153937230 Pathogen - hypothetical protein CLC_3136 1 None None None 153935315 Common dnaX DNA polymerase III, gamma and tau subunits CLC_0051 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 153937371 Common - putative multidrug export ATP-binding/permease protein CLC_0501 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 153936408 Pathogen - hypothetical protein CLC_2571 1 None None None 153937173 Common grdX GrdX protein CLC_1295 6 None None None 153935645 Common hisB imidazoleglycerol-phosphate dehydratase CLC_1599 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 153935066 Common - putative lipoprotein CLC_2472 1 COG5510 COG5510, Predicted small secreted protein Function unknown 153936041 Pathogen - hypothetical protein CLC_2178 1 None None None 153935902 Common - flagellar basal body rod protein CLC_2512 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 153936610 Common pth peptidyl-tRNA hydrolase CLC_3518 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 153935968 Common - small, acid-soluble spore protein alpha CLC_1732 15 None None None 153935721 Common - hypothetical protein CLC_1435 6 None None None 153935158 Common - putative PTS system, L-Ascorbate family, IIB component CLC_2095 29 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 153934629 Common - putative high-affinity branched chain amino acid ABC transporter, ATP-binding protein CLC_0530 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153935729 Common - transcription antiterminator CLC_0933 29 COG3711 BglG, Transcriptional antiterminator Transcription 153936964 Common - putative transketolase, C-terminal subunit CLC_3337 229 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 153936619 Common hemB delta-aminolevulinic acid dehydratase CLC_0978 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 153936268 Common - hemolysin A CLC_1824 132 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 153937650 Common - hypothetical protein CLC_3279 1 None None None 153935738 Common - bacterial microcompartments family protein CLC_2051 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 153937477 Common - glycosyl transferase, group 2 family protein CLC_2603 118 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153937803 Common - NADH dehydrogenase family protein CLC_2333 176 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 153936099 Common gidB methyltransferase GidB CLC_3640 203 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 153936954 Common - oxidoreductase, aldo/keto reductase family CLC_1037 195 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 153937472 Common - polar amino acid uptake ABC transporter, PAAT family, amino acid-binding protein CLC_1224 168 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153935071 Common - hypothetical protein CLC_0608 7 COG4758 COG4758, Predicted membrane protein Function unknown 153935843 Common npr-2 thermolysin metallopeptidase CLC_1479 47 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 153936974 Common - xanthine/uracil permease family protein CLC_1953 6 COG2252 COG2252, Permeases General function prediction only 153934704 Common flhG flagellar biosynthesis protein FlhG CLC_2518 241 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153935556 Common - RNA polymerase sigma-70 factor family CLC_1652 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153937673 Common - transaldolase CLC_1331 166 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 153937490 Common - transcriptional regulator, TetR family CLC_1236 30 COG1309 AcrR, Transcriptional regulator Transcription 153934982 Common - electron transport complex, RnfABCDGE type, E subunit CLC_0429 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 153934874 Common - RNA polymerase sigma-70 factor, ECF family CLC_0891 152 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153937756 Common - hypothetical protein CLC_3446 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 153936502 Common - ABC transporter, ATP-binding protein CLC_2665 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153936256 Common - putative peptidase CLC_0209 141 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153935819 Common - putative lipoprotein CLC_0640 3 None None None 153936531 Common cheW chemotaxis protein CheW CLC_2626 124 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 153936959 Common - iron chelate uptake ABC transporter, FeCT family, solute-binding protein CLC_1100 77 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 153936366 Common - hypothetical protein CLC_1157 14 None None None 153936196 Common - putative Fe] hydrogenase, electron-transfer subunit CLC_1792 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 153934652 Common - hypothetical protein CLC_1683 2 None None None 153937036 Common - transcriptional regulator, LysR family CLC_1608 189 COG0583 LysR, Transcriptional regulator Transcription 153937685 Common grdC glycine reductase complex component C, beta subunit CLC_1301 9 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 153934798 Common - hypothetical protein CLC_0727 1 None None None 153935844 Common - ATP-dependent metalloprotease CLC_0437 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 153935469 Pathogen - hypothetical protein CLC_2004 1 None None None 153937682 Common pepD-2 aminoacyl-histidine dipeptidase CLC_2155 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 153937132 Common ribAB bifunctional riboflavin biosynthesis protein RibAB CLC_2763 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 153936649 Common - sodium:alanine symporter family protein CLC_2799 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 153937040 Common - exopolysaccharide biosynthesis protein CLC_0888 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 153935736 Common - putative drug resistance ABC transporter, ATP-binding protein CLC_3249 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153935565 Pathogen - hypothetical protein CLC_1191 1 None None None 153935608 Common secA preprotein translocase, SecA subunit CLC_0227 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 153937804 Common sigE RNA polymerase sigma-E factor CLC_2391 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 153937844 Common - hypothetical protein CLC_2032 43 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 153936791 Common mviN integral membrane protein MviN CLC_2997 191 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 153937124 Common - putative undecaprenol kinase CLC_0378 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 153937667 Common codY GTP-sensing transcriptional pleiotropic repressor CodY CLC_2284 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 153934565 Common - hypothetical protein CLC_3559 14 None None None 153935982 Common - undecaprenyl pyrophosphate synthetase-like protein CLC_1365 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 153936151 Common - dehydrogenase, FMN-dependent CLC_3023 174 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 153936330 Common - DNA-binding response regulator CLC_2236 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936698 Common - PTS system, mannose/fructose/sorbose family, IID component CLC_2721 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 153936265 Common - hypothetical protein CLC_1341 90 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 153935707 Common - LD-carboxypeptidase family protein CLC_2659 48 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 153935165 Common recG ATP-dependent DNA helicase RecG CLC_2350 220 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 153934863 Common - putative seryl-tRNA synthetase CLC_2463 21 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 153934754 Common mreD rod shape-determining protein MreD CLC_2897 7 None None None 153934873 Common - hypothetical protein CLC_0017 3 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 153937609 Common - recombinase, phage RecT family CLC_2421 14 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 153936110 Common - putative ABC transporter, permease protein CLC_2021 33 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 153936209 Common - CAAX amino terminal protease family protein CLC_3137 2 None None None 153937164 Common - hypothetical protein CLC_1095 7 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 153936254 Common - putative ABC transporter, permease protein CLC_3076 1 None None None 153935136 Common - ABC transporter, permease protein CLC_1206 78 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 153935714 Common - hypothetical protein CLC_1558 37 None None None 153936938 Common - peptidase family protein CLC_0163 11 None None None 153935267 Common - putative spore coat protein CLC_1748 5 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 153936759 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CLC_2678 244 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153935073 Common - putative lipoprotein CLC_2404 1 None None None 153937013 Common pyrG CTP synthase CLC_0180 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 153936624 Common - ABC transporter, ATP-binding/permease protein CLC_1629 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153936101 Pathogen - hypothetical protein CLC_1227 1 None None None 153935792 Common buk-2 butyrate kinase CLC_3372 96 COG3426 COG3426, Butyrate kinase Energy production and conversion 153934471 Common truA-2 tRNA pseudouridine synthase A CLC_3391 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 153936298 Common - electron transfer flavoprotein, beta subunit/FixA family protein CLC_3108 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 153936727 Common - hypothetical protein CLC_3374 19 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 153935374 Common - putative protease CLC_3519 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 153936843 Pathogen - hypothetical protein CLC_2933 1 None None None 153937692 Common rpmH ribosomal protein L34 CLC_3647 10 None None None 153935939 Common accC acetyl-CoA carboxylase, biotin carboxylase CLC_3574 231 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 153937424 Common - PIN/TRAM domain protein CLC_3454 48 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 153935910 Pathogen - hypothetical protein CLC_3118 1 None None None 153936612 Common - PTS system, maltose/glucose-specfic, IIBC component CLC_0327 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 153935485 Common thiM-2 hydroxyethylthiazole kinase CLC_2176 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 153937185 Pathogen - hypothetical protein CLC_0296 1 None None None 153935016 Common - hypothetical protein CLC_2239 43 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 153937446 Pathogen - hypothetical protein CLC_1284 1 None None None 153937496 Common - hypothetical protein CLC_2127 1 None None None 153937284 Common - PhoH family protein CLC_0557 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 153937536 Common - hypothetical protein CLC_1505 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 153935160 Common - transcriptional regulator, AraC family CLC_0656 98 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 153937768 Common ctsR transciptional repressor CtsR CLC_3461 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 153937135 Common flgB flagellar basal-body rod protein FlgB CLC_2540 54 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 153934772 Pathogen - hypothetical protein CLC_1403 1 None None None 153935865 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CLC_1449 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153934978 Common - hypothetical protein CLC_0995 1 None None None 153935193 Common - putative diguanylate cyclase CLC_3306 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153936033 Pathogen - hypothetical protein CLC_0855 1 None None None 153936576 Common iscS-2 cysteine desulfurase CLC_2440 241 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 153937268 Common - DNA-binding protein CLC_1280 104 COG1396 HipB, Predicted transcriptional regulators Transcription 153935221 Common - electron transfer flavoprotein, beta subunit/FixA family protein CLC_2138 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 153937271 Common - hypothetical protein CLC_0043 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 153936538 Common - deoxynucleotide triphosphohydrolase family protein CLC_2835 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 153936910 Common - putative spermidine/putrescine ABC transporter, permease protein/spermidine/putrescine-binding protein CLC_0620 235 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153935992 Common - transcriptional regulator, MarR family CLC_0697 47 COG1846 MarR, Transcriptional regulators Transcription 153935118 Common - DnaA domain protein CLC_2752 9 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 153934900 Common - putative comE operon protein 1 CLC_2875 72 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 153937775 Common - sensor histidine kinase CLC_0663 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153937049 Common - phosphoribosylformylglycinamidine synthase CLC_2452 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 153937117 Common - ABC transporter, ATP-binding protein CLC_2082 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153935128 Common - hypothetical protein CLC_3004 4 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153935572 Common - MRP protein-like protein CLC_0135 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153936712 Common - methyltransferase, UbiE/COQ5 family, selenocysteine-containing CLC_0814 157 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153935259 Common hisH imidazole glycerol phosphate synthase, glutamine amidotransferase subunit CLC_1600 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 153935964 Common pepD-3 aminoacyl-histidine dipeptidase CLC_2766 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 153935063 Common - amino acid permease family protein CLC_0401 172 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153935246 Common - hypothetical protein CLC_1611 69 COG2391 COG2391, Predicted transporter component General function prediction only 153935663 Common - hypothetical protein CLC_2481 11 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 153935824 Common - amino acid/peptide transporter CLC_1975 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 153937678 Common - hypothetical protein CLC_2136 10 COG3949 COG3949, Uncharacterized membrane protein Function unknown 153935719 Common rplU ribosomal protein L21 CLC_2886 202 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 153937236 Common - putative 2-dehydro-3-deoxygluconokinase CLC_0352 107 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153936921 Common prs ribose-phosphate pyrophosphokinase CLC_3522 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 153935537 Common - RNA-binding protein CLC_1722 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 153934616 Pathogen - hypothetical protein CLC_2314 1 None None None 153937699 Common - S4 domain protein CLC_3511 37 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 153935783 Common - DNA-binding response regulator CLC_0842 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936465 Common - stage III sporulation protein AH CLC_1832 8 None None None 153937208 Common - GGDEF domain protein CLC_1334 129 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 153937732 Common - hypothetical protein CLC_1649 13 None None None 153935260 Common maf maf protein CLC_2901 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 153934605 Pathogen - hypothetical protein CLC_2920 1 None None None 153936590 Common - UVR domain protein CLC_3460 19 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 153937456 Common - metallo-beta-lactamase family protein CLC_0711 90 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 153936144 Common - hypothetical protein CLC_2224 1 None None None 153934517 Common sagH ABC transporter, ATP-binding/permease protein SagH CLC_0567 50 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 153936731 Common - hypothetical protein CLC_0144 6 None None None 153935201 Common tpiA triosephosphate isomerase CLC_0284 225 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 153937260 Common - hypothetical protein CLC_2722 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 153937755 Common buk-1 butyrate kinase CLC_3370 133 COG3426 COG3426, Butyrate kinase Energy production and conversion 153935989 Common - glycyl-radical enzyme activating family protein CLC_2059 69 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 153934583 Common bioB biotin synthase CLC_2183 188 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 153936208 Common gatA glutamyl-tRNA(Gln) amidotransferase, A subunit CLC_3209 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153937761 Common - hypothetical protein CLC_0928 30 COG2966 COG2966, Uncharacterized conserved protein Function unknown 153936017 Common - putative kinase CLC_1009 17 COG4542 PduX, Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase Secondary metabolites biosynthesis, transport, and catabolism 153934851 Pathogen - hypothetical protein CLC_0603 1 None None None 153937812 Common treR trehalose operon repressor CLC_1935 99 COG2188 PhnF, Transcriptional regulators Transcription 153935333 Common cbiT precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit CLC_0994 73 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 153935311 Pathogen - hypothetical protein CLC_1680 1 None None None 153936845 Common - hypothetical protein CLC_2001 4 None None None 153936919 Common - amino acid permease family protein CLC_0452 169 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 153934767 Common - sensor histidine kinase CLC_1870 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936128 Common - hypothetical protein CLC_2295 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 153936348 Common glyA serine hydroxymethyltransferase CLC_2467 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 153935425 Common - major facilitator superfamily protein CLC_0062 4 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 153934910 Common ansA L-asparaginase, type II CLC_2372 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 153937631 Common - putative type I restriction-modification system, R subunit CLC_0736 94 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 153935598 Common rpsL ribosomal protein S12 CLC_3430 233 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 153936337 Common - hypothetical protein CLC_0175 43 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 153935347 Common - RNA polymerase sigma-70 factor family CLC_0728 10 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153935369 Common rpmE ribosomal protein L31 CLC_0183 187 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 153936221 Common - nucleoside hydrolase, IUNH family CLC_2494 56 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 153935637 Common aorR aor transcriptional regulator CLC_1882 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 153934859 Common - hypothetical protein CLC_0572 3 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 153936769 Pathogen - hypothetical protein CLC_0716 1 None None None 153937378 Common glmS glucosamine--fructose-6-phosphate aminotransferase, isomerizing CLC_3355 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 153937304 Common - iron ABC transporter, iron-binding protein CLC_0365 57 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153934635 Common atpF ATP synthase F0, B subunit CLC_0200 66 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 153936893 Common - ABC transporter ATP-binding/permease protein CLC_1102 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153935661 Common - spore coat protein-like protein CLC_2836 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 153934716 Common - hypothetical protein CLC_3070 52 COG3391 COG3391, Uncharacterized conserved protein Function unknown 153936514 Common - plasmid recombination enzyme CLC_2406 13 None None None 153937111 Common cbiN cobalt transport protein CLC_0972 41 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 153935413 Common - AP endonuclease, family 2 CLC_2639 46 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 153936818 Common - hypothetical protein CLC_3261 3 None None None 153934782 Common - thioesterase family protein CLC_1203 105 COG0824 FcbC, Predicted thioesterase General function prediction only 153935284 Common - transcriptional regulator, GntR family CLC_2813 142 COG1725 COG1725, Predicted transcriptional regulators Transcription 153937644 Common - hypothetical protein CLC_2054 7 None None None 153935447 Common leuS leucyl-tRNA synthetase CLC_0240 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937822 Common - malic enzyme CLC_0266 202 COG0281 SfcA, Malic enzyme Energy production and conversion 153937158 Common - oligopeptide/dipeptide ABC transporter, permease protein CLC_3058 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936396 Common - BadF/BadG/BcrA/BcrD ATPase family protein CLC_3300 61 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 153935545 Common - decarboxylase family protein CLC_0918 128 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 153935940 Common - guanine deaminase CLC_1326 213 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 153937298 Common - amino acid/peptide transporter CLC_2189 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 153937195 Pathogen - putative lipoprotein CLC_0390 1 None None None 153936708 Common metC cystathionine beta-lyase CLC_0782 212 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153937242 Common - DNA-binding response regulator CLC_1088 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153937828 Common - transcriptional regulator, LysR family CLC_3568 192 COG0583 LysR, Transcriptional regulator Transcription 153937341 Common - vanadium-dependent haloperoxidase CLC_0301 7 None None None 153935876 Common - tungstate ABC transporter, tungstate-binding protein CLC_1891 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 153934705 Common - hypothetical protein CLC_0879 4 None None None 153937832 Common fabF 3-oxoacyl-(acyl-carrier-protein) synthase II CLC_3577 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153937290 Common pdp pyrimidine-nucleoside phosphorylase CLC_1806 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 153937362 Common - hypothetical protein CLC_2693 11 None None None 153934499 Common - acetyltransferase, GNAT family CLC_0063 125 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153937709 Common bcrA bacitracin ABC transporter, ATP-binding protein BcrA CLC_1231 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153936118 Pathogen - hypothetical protein CLC_2922 1 None None None 153935302 Common - hypothetical protein CLC_2769 1 None None None 153936211 Common - hypothetical protein CLC_2745 4 None None None 153937397 Common - hypothetical protein CLC_0244 2 None None None 153937700 Common - hypothetical protein CLC_1210 161 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153935141 Common - hypothetical protein CLC_1450 12 COG5418 COG5418, Predicted secreted protein Function unknown 153934536 Common - restriction/helicase domain protein CLC_0705 164 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 153935675 Common - hypothetical protein CLC_3071 7 None None None 153935054 Pathogen - hypothetical protein CLC_0137 1 None None None 153934939 Pathogen - hypothetical protein CLC_1307 1 None None None 153935274 Common hydA dihydropyrimidinase CLC_2783 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 153937443 Common - hypothetical protein CLC_0924 5 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153936450 Common - electron transport complex, RnfABCDGE type, B subunit CLC_0431 97 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 153937831 Common - STE like transcription factor domain protein CLC_1335 13 COG5298 COG5298, Uncharacterized protein conserved in bacteria Function unknown 153934888 Common rpmD ribosomal protein L30 CLC_3407 140 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 153934917 Common - glycosyl transferase, group 2 family protein CLC_1336 205 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153937142 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CLC_0362 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153936436 Common - acetyltransferase, GNAT family CLC_1135 5 COG0456 RimI, Acetyltransferases General function prediction only 153935668 Common - PTS system, lactose/cellobiose-specific family, IIB component CLC_3302 32 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 153936162 Common - acetyltransferase, GNAT family CLC_0772 37 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153936772 Common - putative flavin reductase CLC_3088 74 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153935247 Common - zinc transporter, ZIP family CLC_1220 90 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 153937404 Pathogen - hypothetical protein CLC_0951 1 None None None 153935236 Common - acetyltransferase, GNAT family CLC_0392 11 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153936644 Pathogen - hypothetical protein CLC_0635 1 None None None 153934894 Common panC pantoate--beta-alanine ligase CLC_0490 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 153934966 Common topB DNA topoisomerase III CLC_1327 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 153936784 Common pcaC-2 4-carboxymuconolactone decarboxylase CLC_1927 58 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 153936353 Common - HIT family protein CLC_1351 169 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 153937616 Common - hypothetical protein CLC_0961 104 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 153937356 Common folC FolC bifunctional protein CLC_3072 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 153935362 Common - hydrolase, carbon-nitrogen family CLC_1763 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 153935322 Common - nitroreductase family protein CLC_1420 104 COG0778 NfnB, Nitroreductase Energy production and conversion 153937389 Common mgtA magnesium-translocating P-type ATPase CLC_2768 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 153935655 Common - tetracycline resistance domain protein CLC_2042 6 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 153936597 Common purB adenylosuccinate lyase CLC_2242 186 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 153935908 Common - putative nimA protein CLC_0688 31 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 153934508 Common - transcriptional regulator, GntR family CLC_0587 25 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 153937517 Common - hypothetical protein CLC_2860 1 None None None 153936967 Common - hypothetical protein CLC_2013 14 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 153936736 Common - acetyltransferase, GNAT family CLC_1163 121 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153937497 Common - polar amino acid uptake ABC transporter, PAAT family, amino acid-binding protein CLC_0520 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153936608 Pathogen - hypothetical protein CLC_0517 1 None None None 153934927 Common cat-2 chloramphenicol acetyltransferase CLC_1966 21 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 153937281 Common - hesB family protein CLC_1734 4 None None None 153937419 Pathogen - hypothetical protein CLC_2029 1 None None None 153935156 Common xth exodeoxyribonuclease III CLC_1516 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 153934835 Common pdxK pyridoxine kinase CLC_1426 40 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 153937470 Common asd aspartate-semialdehyde dehydrogenase CLC_3061 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 153937171 Common - hypothetical protein CLC_1421 1 None None None 153935951 Pathogen - hypothetical protein CLC_2375 1 None None None 153937090 Common - hypothetical protein CLC_2632 1 None None None 153935445 Common - PrdA domain protein CLC_2342 2 None None None 153934500 Common - hypothetical protein CLC_2473 4 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 153937792 Common - hypothetical protein CLC_2192 3 None None None 153936100 Common - transcriptional regulator, AraC family CLC_1627 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153935811 Common - sensor histidine kinase CLC_1025 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153934809 Common - hypothetical protein CLC_1053 2 None None None 153935209 Common tlp small, acid-soluble spore protein tlp CLC_1087 6 None None None 153937041 Pathogen - putative lipoprotein CLC_1396 1 None None None 153935800 Common cotS spore coat protein CotS CLC_0162 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 153934665 Common - lipase/acylhydrolase, GDSL family CLC_2573 7 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 153936092 Common - sulfite/nitrite reductase family protein CLC_1719 162 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 153936112 Common - carbon starvation protein CstA CLC_0607 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 153935386 Common - hypothetical protein CLC_0789 14 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 153937178 Common - hypothetical protein CLC_2084 15 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 153935653 Pathogen - hypothetical protein CLC_1419 1 None None None 153936652 Common hupL [Ni/Fe] hydrogenase, large subunit CLC_1782 100 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 153935318 Common - radical SAM domain protein CLC_2966 113 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 153934937 Common prdE PrdE protein CLC_2327 2 None None None 153934990 Common - glycosyl hydrolase, family 18 CLC_2709 41 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 153935433 Common sagB streptolysin associated protein SagB CLC_0561 59 COG0778 NfnB, Nitroreductase Energy production and conversion 153937051 Common - putative DNA-binding protein CLC_2408 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 153935629 Common - endodeoxyribonuclease RusA family protein CLC_3256 2 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 153935178 Common map-2 methionine aminopeptidase, type I CLC_3555 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 153935456 Common - hypothetical protein CLC_2276 2 None None None 153934881 Common - hypothetical protein CLC_2787 18 None None None 153936600 Common - hypothetical protein CLC_0393 4 None None None 153936198 Common map-1 methionine aminopeptidase, type I CLC_3403 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 153935890 Common - hypothetical protein CLC_0703 5 None None None 153936009 Common - hypothetical protein CLC_1567 19 COG5564 COG5564, Predicted TIM-barrel enzyme, possibly a dioxygenase General function prediction only 153934824 Common - putative DNA polymerase III, epsilon subunit CLC_1700 3 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 153936972 Common rpsD-1 ribosomal protein S4 CLC_3350 241 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 153937657 Common nadB L-aspartate oxidase CLC_1485 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 153937856 Common alaS alanyl-tRNA synthetase CLC_2435 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153936979 Common - hypothetical protein CLC_0646 23 COG4843 COG4843, Uncharacterized protein conserved in bacteria Function unknown 153934830 Common - hypothetical protein CLC_0044 3 COG3937 COG3937, Uncharacterized conserved protein Function unknown 153935682 Common - DNA-binding response regulator CLC_1093 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153935958 Common - peptide/opine/nickel uptake ABC transporter, PepT family, substrate-binding protein CLC_1391 214 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153935237 Common - methyl-accepting chemotaxis protein CLC_2704 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153934547 Common - polar amino acid uptake family ABC transporter, PAAT family, ATP-binding protein CLC_1439 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153935776 Pathogen - hypothetical protein CLC_1622 1 None None None 153936260 Common hlyIII hemolysin III CLC_1488 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 153934523 Common fmt methionyl-tRNA formyltransferase CLC_2364 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 153935924 Common lysC aspartokinase II CLC_3282 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 153936119 Common - probable proton-coupled thiamine transporter YuaJ CLC_0612 13 COG3859 COG3859, Predicted membrane protein Function unknown 153936339 Common - aminotransferase, class V CLC_0420 234 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 153936861 Common - xanthine dehydrogenase family protein, molybdopterin-binding subunit CLC_0317 121 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 153935617 Common gyrA DNA gyrase, A subunit CLC_0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 153936457 Common - carbohydrate uptake ABC transporter, CUT1 family, permease protein CLC_1550 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153937322 Common - hypothetical protein CLC_1736 2 None None None 153937548 Common - hypothetical protein CLC_1969 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 153934490 Common grdE glycine reductase complex component B, alpha and beta subunits CLC_1296 8 None None None 153936042 Common - helicase, RecD/TraA family CLC_0223 147 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 153936372 Common spoVG stage V sporulation protein G CLC_3524 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 153934841 Common - hydrolase, TatD family CLC_0125 239 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 153934658 Common - hypothetical protein CLC_2804 83 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 153936470 Common fldB R-phenyllactate dehydratase, B subunit CLC_3232 16 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153934492 Common - transcriptional regulator, AbrB family CLC_0111 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 153937334 Common glvA-1 maltose-6'-phosphate glucosidase CLC_0326 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 153937102 Common - putative iron-sulfur cluster assembly protein CLC_2439 159 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 153937241 Pathogen - hypothetical protein CLC_2414 1 None None None 153937151 Common - putative ABC transporter, ATP-binding/permease protein CLC_2205 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153936406 Common - transcriptional activator, putative, Baf family CLC_3486 130 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 153936394 Common - hypothetical protein CLC_1122 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 153937720 Common - transcriptional regulator, AraC family CLC_3554 112 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153934671 Common - flgN family protein CLC_2615 1 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 153936811 Common - putative ABC transporter, permease protein CLC_0493 16 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 153937743 Common - HD domain protein CLC_0983 4 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 153936674 Common rpsB ribosomal protein S2 CLC_2283 238 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 153934678 Common - radical SAM domain protein CLC_2018 16 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 153937075 Common - hypothetical protein CLC_2788 57 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 153935254 Pathogen - hypothetical protein CLC_0502 1 None None None 153936107 Common pyrR-1 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase CLC_1514 121 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 153937034 Common - hypothetical protein CLC_1592 4 None None None 153936431 Common - hypothetical protein CLC_2791 15 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 153935126 Common - conserved hypothetical protein TIGR01033 CLC_2975 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 153934693 Common rnr ribonuclease R CLC_0288 203 COG0557 VacB, Exoribonuclease R Transcription 153935089 Common - potassium uptake protein, TrkA family CLC_3036 114 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 153937555 Common moeB molybdopterin biosynthesis protein MoeB CLC_1879 222 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 153937785 Common - FAD-dependent oxidoreductase CLC_1120 151 COG0579 COG0579, Predicted dehydrogenase General function prediction only 153934770 Common - HDIG domain protein CLC_0680 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 153937731 Common - glycerol dehydrogenase CLC_1945 119 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 153934714 Common - putative macrolide efflux ABC transporter, ATP-binding protein CLC_0133 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153936785 Common - hypothetical protein CLC_0984 1 None None None 153936358 Common - putative ABC transporter, permease protein CLC_1917 46 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 153936523 Common - putative endoribonuclease L-PSP CLC_1906 178 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153935723 Pathogen - hypothetical protein CLC_1844 1 None None None 153935822 Common - ABC transporter, ATP-binding protein CLC_0494 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153936283 Pathogen ha17 haemagglutinin component HA17 CLC_0858 1 None None None 153936829 Common - hypothetical protein CLC_2334 2 None None None 153934633 Common arsB arsenical-resistance protein CLC_0813 142 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 153937574 Common hbd 3-hydroxybutyryl-CoA dehydrogenase CLC_3111 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 153937738 Common trx thioredoxin CLC_3378 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 153936183 Common - V-type ATPase, K subunit CLC_2502 23 None None None 153937412 Common - phosphodiesterase, MJ0936 family CLC_3203 65 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153935217 Common - type IV leader peptidase family protein CLC_1353 118 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153935471 Common - DJ-1/PfpI family protein CLC_0446 101 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153935002 Common - hypothetical protein CLC_2310 11 None None None 153937216 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CLC_1740 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 153936088 Common - putative PTS system, L-ascorbate family, IIA component CLC_2096 47 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 153936569 Pathogen - hypothetical protein CLC_2321 1 None None None 153936446 Common - transcriptional regulator, AraC family CLC_0739 134 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153934989 Common nrdB ribonucleoside-diphosphate reductase, beta subunit CLC_2689 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 153937255 Common - putative 3-dehydroquinate synthase CLC_2089 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 153935441 Common acoC TPP-dependent acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase CLC_1659 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 153937300 Pathogen - hypothetical protein CLC_2354 1 None None None 153936827 Pathogen - hypothetical protein CLC_2275 1 None None None 153934570 Common fliM flagellar motor switch protein FliM CLC_2618 108 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 153936313 Common spoIIID stage III sporulation protein D CLC_0210 15 None None None 153936852 Common - hypothetical protein CLC_3127 1 None None None 153935078 Common - LysM domain protein CLC_0165 13 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 153934702 Common - cyclic nucleotide-binding protein CLC_2817 138 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153936517 Common - putative glutamine synthetase CLC_3543 222 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 153934829 Common - DNA-3-methyladenine glycosylase CLC_1303 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 153937097 Common arcC carbamate kinase CLC_2466 68 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 153937875 Common - hypothetical protein CLC_2073 8 COG3878 COG3878, Uncharacterized protein conserved in bacteria Function unknown 153935857 Common spoIIIAF stage III sporulation protein AF CLC_1834 6 None None None 153935763 Common - haloacid dehalogenase, IB family protein CLC_1132 34 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 153935012 Common - peptide/opine/nickel uptake ABC transporter, PepT family, permease protein CLC_1392 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936496 Common - hypothetical protein CLC_2446 25 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 153936133 Common fliG flagellar motor switch protein fliG CLC_2536 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 153934573 Common - hypothetical protein CLC_1607 59 None None None 153936822 Common hypB hydrogenase accessory protein HypB CLC_0506 150 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 153936129 Common - hypothetical protein CLC_0178 12 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 153934958 Common - hypothetical protein CLC_1234 4 None None None 153936361 Common - sensory box-containing [Fe] hydrogenase CLC_1772 36 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 153936685 Pathogen - hypothetical protein CLC_0036 1 None None None 153936820 Common - putative lipoprotein CLC_0537 89 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 153936592 Common manA mannose-6-phosphate isomerase, class I CLC_0468 48 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 153936344 Common sun ribosomal RNA small subunit methyltransferase B CLC_2362 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 153936622 Pathogen - hypothetical protein CLC_1788 1 None None None 153936122 Common - hypothetical protein CLC_1252 46 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 153937327 Common - putative Immunity repressor protein CLC_2756 3 COG1709 COG1709, Predicted transcriptional regulator Transcription 153936149 Pathogen - hypothetical protein CLC_2324 1 None None None 153934651 Common - hypothetical protein CLC_3242 67 COG0398 COG0398, Uncharacterized conserved protein Function unknown 153936985 Common - hypothetical protein CLC_1047 9 None None None 153934943 Common - kinase, PfkB family CLC_1211 145 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153936245 Common - hypothetical protein CLC_3566 11 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 153937205 Common - hypothetical protein CLC_2685 24 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 153937867 Common flgC flagellar basal-body rod protein FlgC CLC_2539 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 153935522 Common polC DNA polymerase III, alpha subunit, Gram-positive type CLC_2270 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 153935830 Common valS valyl-tRNA synthetase CLC_3073 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153937414 Common ispA geranyltranstransferase CLC_1827 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 153934890 Common fliK flagellar hook-length control protein CLC_2532 8 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 153936485 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase CLC_3480 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 153936477 Common - heavy metal binding protein CLC_0786 39 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153937676 Common - hypothetical protein CLC_2323 11 None None None 153936835 Common - hypothetical protein CLC_0130 1 None None None 153934984 Common ispF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CLC_0114 188 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 153934620 Common - putative antibiotic transporter sensor protein CLC_1616 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935102 Common - radical SAM domain protein CLC_2591 86 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 153936671 Common - formate acetyltransferase CLC_2060 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 153936364 Common - hypothetical protein CLC_1059 27 COG3875 COG3875, Uncharacterized conserved protein Function unknown 153937314 Common - putative cell division protein FtsL CLC_3508 2 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 153934736 Common cobJ precorrin-3B C17-methyltransferase CLC_1005 163 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 153935515 Common scpA segregation and condensation protein A CLC_1800 143 COG1354 COG1354, Uncharacterized conserved protein Function unknown 153935759 Common rplK ribosomal protein L11 CLC_3437 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 153936756 Common - iron compound ABC transporter, iron compound-binding protein CLC_0368 38 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153936239 Common - alcohol dehydrogenase, iron-containing CLC_2068 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 153935887 Common - transcriptional regulator, MarR family CLC_2173 95 COG1846 MarR, Transcriptional regulators Transcription 153935210 Common - radical SAM domain protein CLC_3537 49 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 153936286 Common - hypothetical protein CLC_3311 88 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153937004 Common - oxidoreductase, FAD-binding CLC_3373 80 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 153935108 Common - hypothetical protein CLC_1073 2 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 153935975 Common hemK protein-(glutamine-N5) methyltransferase, release factor-specific CLC_0186 215 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 153934540 Common - hypothetical protein CLC_2108 3 None None None 153937065 Common - hypothetical protein CLC_2923 6 None None None 153934752 Common cloSI clostripain CLC_1864 11 None None None 153935392 Common - transcriptional regulator, LacI family CLC_0148 131 COG1609 PurR, Transcriptional regulators Transcription 153937809 Common - putative transcriptional regulator CLC_1281 14 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 153936036 Common - haloacid dehalogenase, IA family protein CLC_3531 148 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153935498 Common - stage III sporulation protein AG CLC_1833 15 None None None 153935803 Pathogen - hypothetical protein CLC_2036 1 None None None 153936695 Pathogen - hypothetical protein CLC_1357 1 None None None 153936193 Common - putative NADPH-dependent FMN reductase CLC_3552 45 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153935292 Common - hypothetical protein CLC_1413 29 None None None 153936388 Pathogen - hypothetical protein CLC_2565 1 None None None 153936942 Common - electron transfer flavoprotein, alpha subunit/FixB family protein CLC_2137 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 153937505 Common - hypothetical protein CLC_2967 7 None None None 153935023 Common - vanW-like family protein CLC_0271 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 153935754 Common - hypothetical protein CLC_2345 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 153936173 Common trxB thioredoxin-disulfide reductase CLC_1298 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153937486 Common - hypothetical protein CLC_1430 5 None None None 153936990 Common acoA TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit CLC_1656 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 153937082 Common - putative ABC transporter, solute-binding protein CLC_1158 33 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153934906 Common rpmC ribosomal protein L29 CLC_3417 175 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 153934486 Common - membrane protein, VanZ family CLC_2663 5 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 153934686 Common - germination protein, Ger(x)C family CLC_1924 14 None None None 153935583 Common - penicillin-binding protein, 1A family CLC_2985 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 153935553 Pathogen - hypothetical protein CLC_3219 1 None None None 153936970 Common - putative ABC transporter, substrate-binding protein CLC_3078 48 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153937591 Common - hypothetical protein CLC_2209 3 None None None 153935606 Common hypE hydrogenase expression/formation protein HypE CLC_1775 127 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 153936804 Common moaD molybdopterin converting factor subunit 1 CLC_1880 14 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 153936029 Common - sensor histidine kinase CLC_3293 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935984 Pathogen - tetratricopeptide repeat protein CLC_0503 1 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 153936952 Common - hypothetical protein CLC_1339 14 None None None 153936428 Common - hypothetical protein CLC_2026 6 None None None 153934871 Common - hypothetical protein CLC_0759 1 None None None 153937331 Common - cytidine/deoxycytidylate deaminase family protein CLC_0194 67 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 153935905 Common - transcriptional regulator, LytR family CLC_0654 9 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 153936859 Common eda 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase CLC_0351 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 153935436 Common - hypothetical protein CLC_1021 1 None None None 153937088 Common - HD domain protein CLC_1621 52 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 153935320 Common - ABC Transporter, ATP-binding protein CLC_0763 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937763 Common - putative anion ABC transporter, solute-binding protein CLC_1017 114 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 153937316 Common - hypothetical protein CLC_2954 1 None None None 153936153 Common - thiamine pyrophosphokinase CLC_2356 51 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 153935574 Common - hydrolase, NUDIX family CLC_0539 41 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153934696 Common - DNA-binding response regulator CLC_1871 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936746 Common - thioredoxin family protein CLC_1299 225 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 153936461 Common accA acetyl-CoA carboxylase, carboxyl transferase, alpha subunit CLC_3572 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 153937329 Pathogen - hypothetical protein CLC_2927 1 None None None 153935496 Common - iron compound ABC transporter, ATP-binding protein CLC_0371 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153935614 Common thiD-1 phosphomethylpyrimidine kinase CLC_0525 224 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 153937672 Common - sensor histidine kinase CLC_0411 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935639 Common - mbl protein CLC_0211 189 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 153936830 Common - rod shape-determining protein MreB CLC_2899 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 153934530 Common - transcriptional regulator, TetR family CLC_1074 60 COG1309 AcrR, Transcriptional regulator Transcription 153937399 Common - putative thiosulfate sulfurtransferase CLC_1190 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153936466 Common - conserved hypothetical protein TIGR00043 CLC_2844 198 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 153936565 Common - putative cell wall hydrolase CLC_1361 52 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 153935288 Common - amino acid/peptide transporter CLC_1571 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 153935966 Common - florfenicol/chloramphenicol resistance protein CLC_2734 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 153935749 Pathogen - hypothetical protein CLC_0748 1 None None None 153935339 Common - hypothetical protein CLC_1777 4 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 153935296 Common - O-acetyltransferase family protein CLC_2103 99 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 153936206 Common - hypothetical protein CLC_1329 18 COG5460 COG5460, Uncharacterized conserved protein Function unknown 153934820 Pathogen - hypothetical protein CLC_3346 1 None None None 153935919 Common - putative iron-dependent repressor CLC_0373 105 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 153936642 Common - transcriptional regulator, AraC family CLC_2107 107 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 153936025 Common minE cell division topological specificity factor MinE CLC_2893 68 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 153937450 Common - oxidoreductase, short chain dehydrogenase/reductase family CLC_2159 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 153934607 Pathogen - hypothetical protein CLC_1258 1 None None None 153936218 Common flgL flagellar hook-associated protein 3 CLC_2613 87 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153935234 Common - dolichyl-phosphate-mannose-protein mannosyltransferase family protein CLC_0358 26 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 153937023 Common - ABC transporter, ATP-binding protein CLC_0839 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153937180 Pathogen - hypothetical protein CLC_0498 1 None None None 153936766 Common cmk cytidylate kinase CLC_1750 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 153934560 Common - hypothetical protein CLC_2339 5 None None None 153937545 Common - hypothetical protein CLC_1185 2 None None None 153937054 Common - conserved hypothetical protein TIGR00044 CLC_1502 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 153935438 Pathogen ha70 haemagglutinin component HA70 CLC_0857 1 None None None 153936999 Common rbsK ribokinase CLC_1595 187 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153934847 Common - sensor histidine kinase CLC_0669 97 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153935183 Common - hypothetical protein CLC_2698 43 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153935696 Common - carbohydrate uptake ABC transporter, CUT1 family, ATP-binding protein CLC_1548 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153937139 Common - transcriptional regulator, ArsR family CLC_0908 11 COG0640 ArsR, Predicted transcriptional regulators Transcription 153934779 Common - methlytransferase-like protein CLC_0542 88 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153935535 Common - hypothetical protein CLC_3299 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 153934618 Common minD septum site-determining protein MinD CLC_2894 158 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 153935600 Common - metallo-beta-lactamase family protein CLC_2180 53 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153937130 Common - response regulator CLC_0577 210 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153935464 Common - putative cell-surface protein CLC_1387 7 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 153934567 Common - hypothetical protein CLC_2119 2 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 153934553 Common motA-2 chemotaxis MotA protein CLC_2527 116 COG1291 MotA, Flagellar motor component Cell motility and secretion 153936067 Common - peptidyl-arginine deiminase, Porphyromonas-type CLC_0946 84 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 153937681 Common - hypothetical protein CLC_3167 3 None None None 153936636 Common - oxidoreductase, FAD/FMN-binding CLC_1537 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 153936725 Common - hypothetical protein CLC_2223 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 153935526 Common - transcriptional regulator, MarR family CLC_1878 48 COG1846 MarR, Transcriptional regulators Transcription 153935111 Common - hypothetical protein CLC_0749 6 None None None 153934897 Common - hypothetical protein CLC_2234 3 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 153935138 Common - putative ABC transporter, permease protein CLC_1405 130 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153936913 Common - putative transporter CLC_0829 18 COG2426 COG2426, Predicted membrane protein Function unknown 153936793 Common - hypothetical protein CLC_3113 2 None None None 153935827 Common - glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein CLC_1663 145 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 153934689 Common - amidase, hydantoinase/carbamoylase family CLC_0684 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 153934741 Common - putative N-acetylmuramoyl-L-alanine amidase CLC_2409 24 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 153936584 Common - cation efflux family protein CLC_1312 202 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 153934662 Common fabG-1 3-oxoacyl-[acyl-carrier-protein] reductase CLC_0576 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153934865 Common - hypothetical protein CLC_0212 14 None None None 153936719 Common - radical SAM domain protein CLC_2889 66 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 153935794 Common - hypothetical protein CLC_0206 1 None None None 153935191 Common - hypothetical protein CLC_2225 3 None None None 153935934 Common - PRC-barrel domain protein CLC_2389 14 COG1873 COG1873, Uncharacterized conserved protein Function unknown 153935684 Common - hypothetical protein CLC_1779 1 None None None 153936936 Pathogen - hypothetical protein CLC_1787 1 None None None 153935340 Common - hypothetical protein CLC_2352 40 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 153935678 Common rplN ribosomal protein L14 CLC_3415 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 153935010 Common cobK precorrin-6x reductase CLC_1006 47 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 153937669 Common - metallo-beta-lactamase family protein/flavodoxin CLC_2718 84 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 153937031 Pathogen - hypothetical protein CLC_2729 1 None None None 153937561 Common - acetyltransferase, GNAT family CLC_2460 1 COG0456 RimI, Acetyltransferases General function prediction only 153935269 Common - sensor histidine kinase CLC_1867 223 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 153935131 Common rpsH ribosomal protein S8 CLC_3411 247 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 153935805 Common cbiE precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit CLC_0992 70 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 153935042 Common codA cytosine deaminase CLC_2015 77 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153935912 Common - glucose-1-phosphate thymidylyltransferase CLC_1999 238 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 153936332 Common minC septum site-determining protein MinC CLC_2895 88 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 153935379 Pathogen - hypothetical protein CLC_2514 1 None None None 153935623 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase CLC_2971 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 153936424 Common - hemerythrin-like metal-binding domain protein CLC_0591 51 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 153935372 Common - hypothetical protein CLC_2545 1 None None None 153936060 Common - ATPase, AAA family CLC_2442 245 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 153934473 Common - amidase domain protein CLC_2151 8 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 153936251 Pathogen - hypothetical protein CLC_0320 1 None None None 153935163 Common nadA quinolinate synthetase complex, A subunit CLC_1486 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 153937661 Common pyrF orotidine 5'-phosphate decarboxylase CLC_3149 67 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 153935980 Common - putative N-acetylmuramoyl-L-alanine amidase CLC_2913 19 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153935863 Common - acetyltransferase, GNAT family CLC_0904 123 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153934625 Pathogen - hypothetical protein CLC_1290 1 None None None 153935587 Common - methyltransferase, UbiE/COQ5 family CLC_1702 133 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153935901 Common rpsO ribosomal protein S15 CLC_2260 216 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 153936841 Common - hypothetical protein CLC_0846 1 None None None 153935460 Common - CobW/P47K family protein CLC_1528 125 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 153937534 Common msrA methionine-S-sulfoxide reductase CLC_1868 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 153935243 Common prfC peptide chain release factor 3 CLC_3274 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 153935483 Common spoIIE stage II sporulation protein E CLC_3491 22 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 153936779 Common - tetrapyrrole methylase family protein CLC_0109 212 COG0313 COG0313, Predicted methyltransferases General function prediction only 153935143 Common - hypothetical protein CLC_1909 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 153936546 Common - response regulator CLC_1051 177 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 153934968 Common mtbC dimethylamine corrinoid protein CLC_1530 173 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 153937221 Common - uracil permease CLC_1515 122 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 153936599 Common - hypothetical protein CLC_1518 3 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 153937621 Common trkH Trk system potassium uptake protein TrkH CLC_1356 139 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153937623 Common - indigoidine synthase A family protein CLC_1212 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 153936116 Common - putative lipoprotein CLC_1404 52 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153935262 Common npr-1 thermolysin metallopeptidase CLC_1478 46 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 153937166 Common - hypothetical protein CLC_1000 2 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 153936168 Pathogen - hypothetical protein CLC_1770 1 None None None 153935276 Common ytfJ sporulation protein YtfJ CLC_1798 21 COG3874 COG3874, Uncharacterized conserved protein Function unknown 153935568 Pathogen - hypothetical protein CLC_0760 1 None None None 153934817 Common - ABC transporter, ATP-binding protein CLC_1248 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153934903 Common - PTS system, glucose/glucoside family, IIA component CLC_0338 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 153934656 Common - sensor histidine kinase CLC_2078 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153937422 Common - hypothetical protein CLC_2120 2 None None None 153935300 Common - transcriptional regulator, LysR family CLC_0700 192 COG0583 LysR, Transcriptional regulator Transcription 153937564 Common - pyridine nucleotide-disulphide oxidoreductase family protein CLC_0507 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153936676 Common - conserved hypothetical protein TIGR00023 CLC_2100 169 COG0344 COG0344, Predicted membrane protein Function unknown 153936070 Common - primase-related protein CLC_0127 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 153937688 Common - DNA topoisomerase, GyrB/ParE subunit family CLC_2646 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 153935411 Common - conserved hypothetical protein TIGR00257 CLC_2976 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 153935702 Common cobQ cobyric acid synthase CobQ CLC_0968 158 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 153937406 Common - hypothetical protein CLC_1849 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 153937618 Common - hybrid cluster protein CLC_2668 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 153934919 Common - stage III sporulation protein AE CLC_1835 15 None None None 153935673 Common pstS phosphate ABC transporter, phosphate-binding protein CLC_2384 173 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 153937649 Common - hypothetical protein CLC_0151 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 153934953 Pathogen - hypothetical protein CLC_2931 1 None None None 153935360 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 CLC_3019 169 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 153936301 Common safA spore coat assembly protein SafA CLC_1713 51 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 153935512 Common ssb single-strand binding protein CLC_3626 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 153937594 Common - hypothetical protein CLC_0005 12 None None None 153937741 Common - MutS domain protein CLC_0685 205 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 153936186 Common rplR ribosomal protein L18 CLC_3409 222 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 153935092 Common - PTS system, glucose family, EIIA component CLC_0330 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 153935671 Common hom-2 homoserine dehydrogenase CLC_1819 216 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 153935256 Common ptbA PTS system, glucose subfamily, IIA component CLC_2714 61 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 153935056 Common murA-2 UDP-N-acetylglucosamine 1-carboxyvinyltransferase CLC_3545 227 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 153937483 Common - radical SAM domain protein CLC_0385 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 153936782 Common - conserved hypothetical protein TIGR00278 CLC_3645 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 153935519 Common - putative peptidase CLC_3253 73 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 153936233 Common - CBS domain protein CLC_0255 212 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 153935313 Common rbr rubrerythrin CLC_1362 78 COG1592 COG1592, Rubrerythrin Energy production and conversion 153937528 Common - conserved hypothetical protein TIGR00159 CLC_3375 68 COG1624 COG1624, Uncharacterized conserved protein Function unknown 153936079 Common prfB peptide chain release factor 2 CLC_0228 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 153935458 Pathogen - hypothetical protein CLC_2680 1 None None None 153936417 Common splB spore photoproduct lyase CLC_0272 27 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 153935121 Common - hypothetical protein CLC_3614 17 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 153935080 Common - putative cyclase CLC_1068 6 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 153937826 Common - drug resistance ABC transporter, RA1 family, ATP-binding protein CLC_1789 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153935543 Common - phenazine biosynthesis protein, PhzF family CLC_1981 119 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 153937390 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CLC_1097 188 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 153935335 Common - HMGL-related enzyme CLC_0483 187 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 153935470 Common - hypothetical protein CLC_1971 10 COG2267 PldB, Lysophospholipase Lipid metabolism 153934601 Common hfq RNA chaperone Hfq CLC_1739 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 153934857 Pathogen - hypothetical protein CLC_2400 1 None None None 153935249 Common dnaE DNA polymerase III, alpha subunit CLC_3317 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 153934861 Common - acetyltransferase, GNAT family CLC_2179 40 COG0456 RimI, Acetyltransferases General function prediction only 153937515 Common - ABC transporter, permease protein CLC_1873 4 None None None 153937369 Common - Fic family protein CLC_0987 66 COG3177 COG3177, Uncharacterized conserved protein Function unknown 153936883 Common - hypothetical protein CLC_0735 1 None None None 153935947 Common - hypothetical protein CLC_2071 5 None None None 153934960 Common - putative sanA protein CLC_0704 40 COG2949 SanA, Uncharacterized membrane protein Function unknown 153935027 Common hpt-1 hypoxanthine phosphoribosyltransferase CLC_2983 131 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 153935020 Common - arsenate reductase ArsC CLC_0808 90 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 153935503 Common thiW thiW protein CLC_2177 13 COG4732 COG4732, Predicted membrane protein Function unknown 153936326 Common - hypothetical protein CLC_0570 1 None None None 153936341 Common - hypothetical protein CLC_3331 12 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 153935353 Common - putative DNA-binding protein CLC_0938 1 None None None 153934912 Common - hypothetical protein CLC_3629 29 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 153935175 Common - hydrolase, NUDIX family CLC_1811 190 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153937248 Common - hypothetical protein CLC_0434 14 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 153937296 Common rpsM ribosomal protein S13 CLC_3399 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 153934784 Common - putative phage infection protein CLC_2821 35 COG1511 COG1511, Predicted membrane protein Function unknown 153936223 Common - hypothetical protein CLC_2885 20 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 153937702 Common - hypothetical protein CLC_1340 11 None None None 153935428 Common - putative macrolide efflux ABC transporter, permease protein CLC_0134 176 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 153934795 Pathogen - hypothetical protein CLC_1983 1 None None None 153936891 Pathogen - hypothetical protein CLC_0943 1 None None None 153934637 Common - hypothetical protein CLC_1316 2 None None None 153937015 Common - hypothetical protein CLC_1681 5 None None None 153934845 Common - sensor histidine kinase CLC_0424 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 153937228 Common - transcriptional regulator, AraC family CLC_1240 89 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153937811 Common glvA-2 maltose-6'-phosphate glucosidase CLC_0337 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 153936742 Pathogen - hypothetical protein CLC_1330 1 None None None 153937343 Common - Na/Pi-cotransporter family protein/PhoU family protein CLC_3388 165 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 153936516 Common aspB-2 aspartate aminotransferase CLC_1961 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153937821 Common - cold shock protein CLC_0341 180 COG1278 CspC, Cold shock proteins Transcription 153934975 Common - bacterial microcompartments family protein CLC_2048 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 153937814 Common - DJ-1/PfpI family protein CLC_0779 28 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 153937286 Common - helicase domain protein CLC_1401 91 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153937773 Common - ABC transporter ATP-binding/permease protein CLC_1628 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153937642 Common - aldehyde dehydrogenase family protein CLC_2061 175 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153936276 Common - hypothetical protein CLC_2984 14 None None None 153935839 Common - transcriptional regulator, LuxR family CLC_1581 51 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 153937360 Common - putative glycolate oxidase CLC_1062 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153935870 Common - radical SAM domain protein CLC_3560 43 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 153935994 Common - putative R-2-hydroxyglutaryl-CoA dehydratase subunit CLC_3628 38 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153937719 Common - hypothetical protein CLC_1636 47 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 153935014 Common - ribosomal protein L32 family protein CLC_2307 32 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 153934521 Common - proton/sodium-glutamate symporter CLC_0622 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 153935778 Common - transcriptional regulator, GntR family CLC_1553 157 COG2186 FadR, Transcriptional regulators Transcription 153936574 Common - hypothetical protein CLC_2810 1 None None None 153937257 Common - putative manganese-dependent inorganic pyrophosphatase CLC_2510 61 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 153937324 Common - putative zinc-dependent hydrolase CLC_0146 85 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 153936650 Common - ABC transporter, ATP-binding protein CLC_1699 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153936044 Common - PTS system, glucitol/sorbitol-specific, IIBC component CLC_3360 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 153936863 Common - aspartokinase CLC_1666 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 153937084 Common - O-glycosyl hydrolase, family 30 CLC_1242 23 COG5520 COG5520, O-Glycosyl hydrolase Cell envelope biogenesis, outer membrane 153936647 Pathogen - hypothetical protein CLC_0662 1 None None None 153937246 Common - putative flavoredoxin CLC_0893 30 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153937153 Common - transcriptional regulator, TetR family CLC_1546 12 COG1309 AcrR, Transcriptional regulator Transcription 153936438 Common - conserved hypothetical protein TIGR00246 CLC_3549 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 153936131 Common def-3 peptide deformylase CLC_2495 206 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 153936825 Common - flagellar operon protein CLC_2530 16 None None None 153937408 Common - CBS domain protein CLC_1170 9 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 153935278 Common sleB spore-cortex-lytic enzyme CLC_0260 50 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 153935619 Common - oligopeptide/dipeptide ABC transporter, oligopeptide/dipeptide-binding protein CLC_3060 193 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153934843 Common rpsP ribosomal protein S16 CLC_2296 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 153936795 Pathogen - hypothetical protein CLC_0540 1 None None None 153937213 Common - hypothetical protein CLC_1186 2 None None None 153936552 Common hypD hydrogenase expression/formation protein HypD CLC_1776 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 153937270 Common lepB-2 signal peptidase I CLC_2291 198 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 153934494 Common - putative 2-hydroxyglutaryl-CoA dehydratase subunit CLC_1584 19 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 153936020 Common - amidase domain protein CLC_1363 7 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 153937553 Pathogen - hypothetical protein CLC_1464 1 None None None 153935563 Common - hypothetical protein CLC_0831 3 None None None 153935734 Common - RNA-metabolizing metallo-beta-lactamase family protein CLC_2430 158 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 153935588 Common rpsC ribosomal protein S3 CLC_3419 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 153934506 Pathogen - hypothetical protein CLC_0956 1 None None None 153935926 Common - cytochrome P450 CLC_1090 35 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 153935892 Pathogen - hypothetical protein CLC_1149 1 None None None 153937787 Common - putative sensory box-containing diguanylate cyclase CLC_1254 188 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153936813 Common - ABC transporter, ATP-binding protein CLC_0898 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153937045 Common - putative oligopeptide ABC transporter, ATP-binding protein CLC_1265 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153936441 Common pheS phenylalanyl-tRNA synthetase, alpha subunit CLC_3034 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 153937387 Common - carbohydrate uptake ABC transporter, CUT1 family, carbohydrate-binding protein CLC_1551 116 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153936658 Common rpsU ribosomal protein S21 CLC_2849 67 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 153935240 Common - hypothetical protein CLC_2597 49 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 153934837 Common - two component regulator three Y motif protein CLC_3218 2 None None None 153935813 Pathogen - hypothetical protein CLC_1454 1 None None None 153934934 Common - hypothetical protein CLC_0599 2 None None None 153935641 Common - polysaccharide deacetylase family protein CLC_2993 101 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153937747 Common - TfoX domain protein CLC_1038 10 COG3070 TfoX, Regulator of competence-specific genes Transcription 153937717 Pathogen - hypothetical protein CLC_1944 1 None None None 153937581 Common pcaC-1 4-carboxymuconolactone decarboxylase CLC_1766 80 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 153934481 Common gcvPA glycine cleavage system P protein, subunit 1 CLC_0752 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 153936606 Common - hypothetical protein CLC_1709 1 None None None 153935581 Common - nitroreductase family protein CLC_1985 141 COG0778 NfnB, Nitroreductase Energy production and conversion 153936901 Common - hypothetical protein CLC_2065 6 None None None 153934729 Common - hypothetical protein CLC_0927 20 COG3610 COG3610, Uncharacterized conserved protein Function unknown 153935739 Common pheB ACT domain protein pheB CLC_2906 14 COG4492 PheB, ACT domain-containing protein General function prediction only 153934883 Common - sensor histidine kinase CLC_1094 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153936614 Common lysP lysine-specific permease CLC_0308 138 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 153937127 Common - lipoprotein, bmp family CLC_0275 106 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 153935747 Common - acetyltransferase, GNAT family CLC_1455 22 COG0456 RimI, Acetyltransferases General function prediction only 153936927 Pathogen - hypothetical protein CLC_2033 1 None None None 153934819 Common - hypothetical protein CLC_0655 4 COG4758 COG4758, Predicted membrane protein Function unknown 153934738 Common - methyl-accepting chemotaxis protein CLC_2681 119 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153935388 Common rplM ribosomal protein L13 CLC_3390 223 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 153936281 Common - ATP-dependent protease CLC_1476 191 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 153937476 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase CLC_1825 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 153934585 Common rpmJ ribosomal protein L36 CLC_3400 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 153934700 Common - hypothetical protein CLC_2517 17 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 153935596 Pathogen - hypothetical protein CLC_1993 1 None None None 153936958 Common - phosphoribosyl transferase domain protein CLC_1952 7 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153936459 Common - acetyltransferase, GNAT family CLC_1033 53 COG0456 RimI, Acetyltransferases General function prediction only 153934803 Common - hypothetical protein CLC_3298 13 None None None 153936528 Common - putative lipoprotein CLC_0659 2 None None None 153937499 Common - transporter, EamA family CLC_0769 151 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153936738 Common - glucokinase regulator-like protein CLC_1381 85 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 153934726 Common - transcriptional regulator, MarR family CLC_2699 26 COG1846 MarR, Transcriptional regulators Transcription 153934832 Common - hypothetical protein CLC_1499 23 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 153936744 Common - hypothetical protein CLC_1388 1 None None None 153936448 Common - hypothetical protein CLC_1850 1 None None None 153936790 Common - [Fe] hydrogenase CLC_3244 65 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 153936718 Common smc chromosome segregation protein SMC CLC_2300 194 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 153936370 Common - DNA-dependent RNA polymerase sigma subunit CLC_2399 14 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 153936094 Common - putative acetyltransferase CLC_3008 184 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 153934676 Common - hypothetical protein CLC_1757 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 153934722 Common upp uracil phosphoribosyltransferase CLC_0193 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 153935847 Common - putative ABC transporter, permease protein CLC_0840 41 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153934718 Pathogen - hypothetical protein CLC_0967 1 None None None 153934641 Common - hypothetical protein CLC_0837 3 None None None 153936007 Common - glutaminase CLC_2684 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 153935706 Pathogen - hypothetical protein CLC_0040 1 None None None 153934827 Common - radical SAM domain protein CLC_2302 146 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 153934603 Common - hypothetical protein CLC_1926 15 None None None 153934765 Common - membrane-spanning protein CLC_2669 7 None None None 153935106 Common prmA ribosomal protein L11 methyltransferase CLC_2853 189 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 153937176 Common - transporter, CorA metal ion transporter family CLC_0097 41 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 153936072 Common - hypothetical protein CLC_2486 46 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 153936969 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CLC_1026 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153935384 Common dapF diaminopimelate epimerase CLC_1856 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 153936897 Pathogen - hypothetical protein CLC_1460 1 None None None 153936188 Common - hypothetical protein CLC_0098 2 None None None 153935510 Common rpsD-2 ribosomal protein S4 CLC_3397 240 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 153936553 Common argG argininosuccinate synthase CLC_2544 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 153935770 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CLC_2648 69 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153934475 Common - polysaccharide deacetylase family protein CLC_2677 94 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153936510 Common - metallo-beta-lactamase family protein CLC_0455 107 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 153935065 Common - hypothetical protein CLC_1408 41 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 153937448 Common - lrgB-like family protein CLC_0383 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 153935716 Pathogen - hypothetical protein CLC_1208 1 None None None 153935402 Common - hypothetical protein CLC_3295 5 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 153935356 Common - sodium:solute symporter family protein CLC_0425 156 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 153937438 Common - putative mutator mutT protein CLC_0706 160 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153936758 Pathogen - hypothetical protein CLC_2642 1 COG2246 COG2246, Predicted membrane protein Function unknown 153937800 Common dapB-1 dihydrodipicolinate reductase CLC_0847 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 153935505 Pathogen - hypothetical protein CLC_2039 1 None None None 153935973 Common - hypothetical protein CLC_2829 33 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 153934951 Pathogen - hypothetical protein CLC_1859 1 None None None 153935282 Common - DegV family protein CLC_0274 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 153934750 Common botR transcriptional regulator BotR, P-21 CLC_0860 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153934962 Common - DNA-binding response regulator CLC_0410 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153936693 Common yajC preprotein translocase, YajC subunit CLC_2969 142 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 153936023 Pathogen - putative lipoprotein CLC_1676 1 None None None 153937002 Common - flavodoxin CLC_2654 47 COG0716 FldA, Flavodoxins Energy production and conversion 153935517 Common - putative lipoprotein CLC_0469 2 None None None 153937460 Common pheT phenylalanyl-tRNA synthetase, beta subunit CLC_3033 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 153937104 Pathogen - hypothetical protein CLC_2795 1 None None None 153935551 Common - hypothetical protein CLC_0701 12 None None None 153936733 Common - glycosyl transferase, group 2 family protein CLC_0356 201 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153935290 Common cobO cob(I)alamin adenosyltransferase CLC_1010 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 153934488 Common - ABC transporter, ATP-binding protein CLC_0643 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153936626 Common spoVB-2 stage V sporulation protein B CLC_3514 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153937503 Common - hypothetical protein CLC_2937 1 None None None 153935752 Common - amino acid permease family protein CLC_2134 108 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 153935099 Common - phosphoglucomutase/phosphomannomutase family protein CLC_3018 207 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 153937467 Common - hypothetical protein CLC_1260 11 COG5663 COG5663, Uncharacterized conserved protein Function unknown 153937420 Common - diacylglycerol kinase/PAP2 family protein CLC_2843 63 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 153936401 Common - PTS system, lactose/cellobiose-specific family, IIA component CLC_3301 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 153936503 Common - hypothetical protein CLC_2153 2 None None None 153934969 Common - conserved hypothetical protein TIGR00046 CLC_2852 195 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 153935044 Pathogen - acetyltransferase, GNAT family CLC_0641 1 None None None 153936948 Common - small, acid-soluble spore protein beta CLC_1733 15 None None None 153936426 Common - sulfatase family protein CLC_2760 62 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 153934680 Common - hypothetical protein CLC_3021 4 None None None 153936146 Common - hypothetical protein CLC_1238 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 153937873 Common tupC tungstate ABC transporter, ATP-binding protein CLC_1889 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153937203 Common purA adenylosuccinate synthetase CLC_3615 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 153937779 Common - sensory box histidine kinase CLC_0398 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 153937576 Common - hypothetical protein CLC_1462 2 None None None 153934941 Common alr-2 alanine racemase CLC_1685 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 153934622 Common - LysM domain protein CLC_0807 16 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153936086 Common hupS [Ni/Fe] hydrogenase, small subunit CLC_1783 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 153937351 Pathogen - hypothetical protein CLC_2396 1 None None None 153937306 Common - hypothetical protein CLC_2319 33 COG1915 COG1915, Uncharacterized conserved protein Function unknown 153937148 Common - ATP:guanido phosphotransferase domain protein CLC_3459 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 153935907 Common - hypothetical protein CLC_0381 3 None None None 153936886 Pathogen - hypothetical protein CLC_1457 1 None None None 153936850 Common cdd cytidine deaminase CLC_2842 113 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 153937099 Common sigH RNA polymerase sigma-H factor CLC_3445 76 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153935646 Pathogen - hypothetical protein CLC_0387 1 None None None 153935145 Common cmr4 CRISPR-associated RAMP protein, Cmr4 family CLC_2115 25 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 153937092 Common motB-1 chemotaxis MotB protein CLC_2148 147 COG1360 MotB, Flagellar motor protein Cell motility and secretion 153936902 Common - hypothetical protein CLC_3310 7 COG5566 COG5566, Uncharacterized conserved protein Function unknown 153935207 Common dapG aspartokinase I CLC_2256 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 153934992 Common - hypothetical protein CLC_2416 16 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 153936421 Common - hypothetical protein CLC_0556 3 None None None 153935741 Common cobS cobalamin 5'-phosphate synthase CLC_0876 144 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 153937233 Pathogen - hypothetical protein CLC_1367 1 None None None 153936519 Common - helicase, UvrD/REP/exonuclease family protein CLC_1358 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153936563 Common - SPFH domain/Band 7 family protein CLC_0463 221 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 153935216 Common - putative oligopeptide ABC transporter, permease protein CLC_1266 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153936472 Pathogen - hypothetical protein CLC_3336 1 None None None 153936837 Common lysA diaminopimelate decarboxilase CLC_3281 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 153935781 Common - hypothetical protein CLC_2548 32 COG4129 COG4129, Predicted membrane protein Function unknown 153937043 Common - hypothetical protein CLC_1273 3 None None None 153934811 Common - hypothetical protein CLC_0761 33 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 153937436 Pathogen - hypothetical protein CLC_0158 1 None None None 153935350 Common - hypothetical protein CLC_2902 2 None None None 153935761 Common - putative metalloprotease CLC_2890 49 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 153935378 Common - hypothetical protein CLC_2114 2 None None None 153934997 Common - acetyltransferase, GNAT family CLC_0912 9 None None None 153935524 Common - dihydrouridine synthase family protein CLC_0729 188 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 153934925 Common - general secretion pathway protein E CLC_1853 180 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 153936269 Common uvrC excinuclease ABC, C subunit CLC_3323 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 153936498 Common - hypothetical protein CLC_0538 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 153936080 Common tig trigger factor CLC_3143 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 153936483 Common - hypothetical protein CLC_1805 5 None None None 153936124 Common - DAK2 domain protein CLC_2351 51 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 153935181 Common - hypothetical protein CLC_0982 12 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153935409 Common - bacterial Ig-like domain protein CLC_1674 19 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 153935394 Common birA birA bifunctional protein CLC_1168 209 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 153937193 Common - methyl-accepting chemotaxis protein CLC_1863 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 153934572 Common - spore maturation protein B CLC_0119 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 153937089 Pathogen - hypothetical protein CLC_0853 1 None None None 153936247 Common - hypothetical protein CLC_2905 61 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 153937736 Pathogen - putative lipoprotein CLC_3077 1 None None None 153934743 Common - RNase3 domain protein CLC_3449 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 153935473 Common fchA methenyltetrahydrofolate cyclohydrolase CLC_1214 39 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 153936479 Common - hydrolase, NUDIX family CLC_0057 86 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 153936453 Common - Sua5/YciO/YrdC/YwlC family protein CLC_0190 241 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 153936873 Common - conserved hypothetical protein TIGR00247 CLC_2428 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 153934575 Common - hypothetical protein CLC_1803 7 None None None 153936983 Common - PRC-barrel domain/MgtE domain/CBS domain protein CLC_0259 166 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 153935855 Common - sodium:dicarboxylate symporter family protein CLC_0291 93 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion