Marinomonas sp. MWYL1, complete genome NC_009654 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 152994330 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mmwyl1_0289 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 152998407 Common - GAF domain-containing protein Mmwyl1_4412 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 152997533 Common - transcriptional regulator, LysR family Mmwyl1_3530 109 COG0583 LysR, Transcriptional regulator Transcription 152997707 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_3706 124 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152994447 Common - Cytochrome-c peroxidase Mmwyl1_0409 95 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 152997876 Common - hypothetical protein Mmwyl1_3877 27 COG4648 COG4648, Predicted membrane protein Function unknown 152997006 Common - protein of unknown function DUF1624 Mmwyl1_2995 27 COG3503 COG3503, Predicted membrane protein Function unknown 152996927 Common - rare lipoprotein B precursor Mmwyl1_2916 6 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 152996248 Common - response regulator receiver protein Mmwyl1_2226 213 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 152997321 Common - hypothetical protein Mmwyl1_3316 21 None None None 152997023 Common - formate dehydrogenase family accessory protein FdhD Mmwyl1_3012 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 152997227 Common - TPR repeat-containing protein Mmwyl1_3221 61 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 152996669 Common - 2-nitropropane dioxygenase NPD Mmwyl1_2656 138 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 152995544 Common - hypothetical protein Mmwyl1_1516 5 None None None 152995674 Common - ABC transporter related Mmwyl1_1648 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152994626 Nonpathogen - hypothetical protein Mmwyl1_0592 1 None None None 152998211 Common - protein of unknown function DUF262 Mmwyl1_4216 44 COG1479 COG1479, Uncharacterized conserved protein Function unknown 152995897 Common - ABC transporter related Mmwyl1_1873 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152998271 Common - ribosomal protein L3 Mmwyl1_4276 232 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 152996442 Common - Phosphotransferase system, phosphocarrier protein HPr Mmwyl1_2420 150 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 152997515 Common - aminotransferase class I and II Mmwyl1_3512 233 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 152998045 Common - NusB antitermination factor Mmwyl1_4049 159 COG0781 NusB, Transcription termination factor Transcription 152996592 Common - Integrase catalytic region Mmwyl1_2575 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997251 Common - sigma 54 modulation protein/ribosomal protein S30EA Mmwyl1_3245 98 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 152998087 Common - ABC transporter related Mmwyl1_4091 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152996200 Common - hypothetical protein Mmwyl1_2178 6 None None None 152996080 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2058 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994877 Common - LmbE family protein Mmwyl1_0845 2 None None None 152996948 Common - protein of unknown function DUF486 Mmwyl1_2937 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 152997057 Common - coenzyme A transferase Mmwyl1_3046 41 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 152994239 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0197 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997296 Common - Phospholipase A(1) Mmwyl1_3291 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 152995840 Common - transcriptional regulator, MarR family Mmwyl1_1816 40 COG1846 MarR, Transcriptional regulators Transcription 152995817 Common - aminotransferase class V Mmwyl1_1792 156 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 152995652 Common - TonB-dependent siderophore receptor Mmwyl1_1625 87 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 152997847 Common - KAP P-loop domain protein Mmwyl1_3848 15 None None None 152996129 Common - AzlC family protein Mmwyl1_2107 104 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 152997159 Common - hypothetical protein Mmwyl1_3150 42 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 152994305 Common - drug resistance transporter, Bcr/CflA subfamily Mmwyl1_0263 143 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994321 Common - DNA polymerase I Mmwyl1_0280 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 152994512 Common - ethanolamine transproter Mmwyl1_0475 160 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 152997500 Common - Beta-ketoacyl synthase Mmwyl1_3497 206 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152996443 Common - magnesium transporter Mmwyl1_2421 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 152997245 Nonpathogen - hypothetical protein Mmwyl1_3239 3 None None None 152995794 Common - ABC transporter related Mmwyl1_1768 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152997620 Common - anti-ECFsigma factor, ChrR Mmwyl1_3618 35 COG3806 ChrR, Transcriptional activator Transcription 152994203 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0161 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995767 Nonpathogen - hypothetical protein Mmwyl1_1741 1 None None None 152996079 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2057 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152997786 Common - protein of unknown function DUF400 Mmwyl1_3785 18 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 152995401 Common - 67-dimethyl-8-ribityllumazine synthase Mmwyl1_1372 172 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 152994786 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Mmwyl1_0752 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 152997109 Common - 3-hydroxyacyl-CoA dehydrogenase PaaC Mmwyl1_3099 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 152995506 Common - MATE efflux family protein Mmwyl1_1477 144 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 152994569 Common - hypothetical protein Mmwyl1_0533 2 None None None 152996855 Common - protein of unknown function DUF493 Mmwyl1_2843 8 COG2921 COG2921, Uncharacterized conserved protein Function unknown 152996023 Common - transcriptional regulator, LysR family Mmwyl1_2001 182 COG0583 LysR, Transcriptional regulator Transcription 152994087 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0044 25 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152994533 Common - 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Mmwyl1_0497 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 152995076 Common - putative metalloendopeptidase, glycoprotease family Mmwyl1_1045 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 152995501 Common - pyruvate carboxyltransferase Mmwyl1_1472 134 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 152997742 Common - Dihydrofolate reductase Mmwyl1_3741 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 152998235 Common - alpha/beta hydrolase fold Mmwyl1_4240 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152994136 Common - Tannase and feruloyl esterase Mmwyl1_0094 20 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 152997396 Common - protein of unknown function DUF1499 Mmwyl1_3393 21 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 152996120 Common - protein of unknown function DUF323 Mmwyl1_2098 107 COG1262 COG1262, Uncharacterized conserved protein Function unknown 152997724 Common - L-asparaginase II Mmwyl1_3723 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 152996043 Nonpathogen - hypothetical protein Mmwyl1_2021 1 None None None 152994674 Common - histone deacetylase superfamily Mmwyl1_0640 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 152995165 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mmwyl1_1136 93 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 152994143 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_0101 120 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152995465 Common - aminotransferase class V Mmwyl1_1436 227 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 152996011 Common - carbohydrate kinase FGGY Mmwyl1_1988 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 152996451 Common - putative inner membrane protein Mmwyl1_2429 3 None None None 152997664 Common - transcriptional regulator, LysR family Mmwyl1_3663 95 COG0583 LysR, Transcriptional regulator Transcription 152995078 Common - Polynucleotide adenylyltransferase region Mmwyl1_1047 163 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 152995215 Nonpathogen - hypothetical protein Mmwyl1_1186 1 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 152996344 Common - ZIP zinc transporter family protein Mmwyl1_2322 23 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 152995982 Common - ATP synthase F0, A subunit Mmwyl1_1958 173 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 152996758 Common - protein of unknown function DUF523 Mmwyl1_2745 67 COG1683 COG1683, Uncharacterized conserved protein Function unknown 152995369 Common - Endonuclease/exonuclease/phosphatase Mmwyl1_1340 31 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 152995404 Common - precorrin-4 C11-methyltransferase Mmwyl1_1375 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 152996019 Common - magnesium and cobalt transport protein CorA Mmwyl1_1997 185 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 152995157 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Mmwyl1_1126 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 152995129 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mmwyl1_1098 173 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 152994440 Common - transport system permease protein Mmwyl1_0402 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152996962 Nonpathogen - hypothetical protein Mmwyl1_2951 2 None None None 152998150 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_4154 125 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996416 Common - Putative lipoprotein-like protein Mmwyl1_2394 40 COG3107 LppC, Putative lipoprotein General function prediction only 152997653 Common - Bile acid:sodium symporter Mmwyl1_3652 89 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 152998361 Common - phosphoesterase PA-phosphatase related Mmwyl1_4366 26 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 152994579 Common - dihydroorotase, multifunctional complex type Mmwyl1_0543 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 152998186 Common - multi-sensor hybrid histidine kinase Mmwyl1_4190 214 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 152996494 Common - NAD-dependent epimerase/dehydratase Mmwyl1_2473 62 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152995956 Common - protein of unknown function UPF0153 Mmwyl1_1932 34 None None None 152994425 Common - Domain of unknown function DUF1852 Mmwyl1_0387 24 None None None 152995936 Common - protein of unknown function DUF453 Mmwyl1_1912 56 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 152998077 Common - choline dehydrogenase Mmwyl1_4081 94 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 152996119 Common - aconitate hydratase 2 Mmwyl1_2097 173 COG1049 AcnB, Aconitase B Energy production and conversion 152998060 Common - protein of unknown function DUF6 transmembrane Mmwyl1_4064 38 COG2962 RarD, Predicted permeases General function prediction only 152996933 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_2922 96 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152994681 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0647 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152998305 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_4310 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 152995021 Common - protein of unknown function DUF404 Mmwyl1_0990 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 152995979 Common - H+transporting two-sector ATPase delta/epsilon subunit Mmwyl1_1955 16 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 152997546 Common - CRISPR-associated protein, Cse3 family Mmwyl1_3543 27 None None None 152996053 Common - RNA binding S1 domain protein Mmwyl1_2031 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 152994194 Common - ABC transporter related Mmwyl1_0152 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152997229 Common - integration host factor, beta subunit Mmwyl1_3223 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 152994379 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0341 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994528 Nonpathogen - hypothetical protein Mmwyl1_0492 3 None None None 152995252 Nonpathogen - hypothetical protein Mmwyl1_1223 1 None None None 152994717 Common - ThiJ/PfpI domain protein Mmwyl1_0683 117 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 152997754 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3753 167 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 152997926 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3929 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997565 Common - Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase-like protein Mmwyl1_3563 18 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 152997358 Common - bifunctional deaminase-reductase domain protein Mmwyl1_3354 69 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 152998258 Common - ribosomal protein S14 Mmwyl1_4263 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 152995387 Common - hypothetical protein Mmwyl1_1358 69 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 152996702 Common - CRISPR-associated protein, Cmr5 family Mmwyl1_2689 8 COG3337 COG3337, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 152995418 Common - transcriptional regulator, LysR family Mmwyl1_1389 193 COG0583 LysR, Transcriptional regulator Transcription 152997220 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein Mmwyl1_3212 119 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 152994789 Common - A/G-specific adenine glycosylase Mmwyl1_0755 231 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 152994163 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0121 224 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 152997361 Common - hypothetical protein Mmwyl1_3357 2 None None None 152997561 Common - DNA-3-methyladenine glycosylase I Mmwyl1_3559 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 152995734 Nonpathogen - hypothetical protein Mmwyl1_1708 1 None None None 152995245 Nonpathogen - hypothetical protein Mmwyl1_1216 1 None None None 152997695 Common - ABC transporter related Mmwyl1_3694 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152996915 Nonpathogen - hypothetical protein Mmwyl1_2904 7 None None None 152996811 Common - 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase Mmwyl1_2799 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 152994999 Common - GCN5-related N-acetyltransferase Mmwyl1_0968 21 COG3153 COG3153, Predicted acetyltransferase General function prediction only 152998100 Common - aldehyde dehydrogenase Mmwyl1_4104 174 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994223 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0181 145 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 152995050 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Mmwyl1_1019 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 152995120 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_1089 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994243 Common - extracellular solute-binding protein, family 3 Mmwyl1_0201 12 None None None 152997368 Common - transposase IS3/IS911 family protein Mmwyl1_3364 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997119 Common - ABC transporter related Mmwyl1_3109 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152996322 Common - transcriptional regulator, AraC family Mmwyl1_2300 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995694 Common - phage Tail Collar domain protein Mmwyl1_1668 36 COG4675 MdpB, Microcystin-dependent protein Function unknown 152995309 Common - surface antigen (D15) Mmwyl1_1280 155 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 152996234 Common - putative signal transduction protein Mmwyl1_2212 43 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 152996535 Common - glucose sorbosone dehydrogenase Mmwyl1_2516 114 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 152998092 Common - isoaspartyl dipeptidase Mmwyl1_4096 21 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 152997915 Common - regulatory protein GntR HTH Mmwyl1_3918 72 COG1802 GntR, Transcriptional regulators Transcription 152997138 Common - transcriptional regulator, LysR family Mmwyl1_3128 138 COG0583 LysR, Transcriptional regulator Transcription 152997761 Common - single-stranded-DNA-specific exonuclease RecJ Mmwyl1_3760 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 152997459 Common - 8-amino-7-oxononanoate synthase Mmwyl1_3456 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 152996953 Common - MscS Mechanosensitive ion channel Mmwyl1_2942 228 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 152995055 Nonpathogen - preprotein translocase, SecG subunit Mmwyl1_1024 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 152997860 Common - hypothetical protein Mmwyl1_3861 20 None None None 152996305 Common - Glycine hydroxymethyltransferase Mmwyl1_2283 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 152996249 Common - yecA family protein Mmwyl1_2227 21 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 152995719 Common - lipid A biosynthesis acyltransferase Mmwyl1_1693 103 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 152995873 Common - major facilitator superfamily MFS_1 Mmwyl1_1849 33 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996505 Common - extracellular solute-binding protein family 1 Mmwyl1_2484 90 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 152996630 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Mmwyl1_2617 223 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 152997478 Common - rfaE bifunctional protein Mmwyl1_3475 144 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 152995720 Common - Mn2+-dependent serine/threonine protein kinase Mmwyl1_1694 20 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 152995744 Common - protein of unknown function DUF539 Mmwyl1_1718 7 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 152994485 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_0448 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152994570 Common - hypothetical protein Mmwyl1_0534 2 None None None 152996693 Common - hypothetical protein Mmwyl1_2680 4 None None None 152994428 Common - hypothetical protein Mmwyl1_0390 14 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 152994262 Common - aminotransferase class I and II Mmwyl1_0220 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152996528 Nonpathogen - hypothetical protein Mmwyl1_2509 1 None None None 152996608 Common - ribosomal protein L35 Mmwyl1_2595 109 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 152996281 Common - Electron-transferring-flavoprotein dehydrogenase Mmwyl1_2259 109 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 152998324 Nonpathogen - hypothetical protein Mmwyl1_4329 1 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 152994991 Common - HupE/UreJ protein Mmwyl1_0960 45 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 152995490 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Mmwyl1_1461 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152996062 Common - tRNA pseudouridine synthase A Mmwyl1_2040 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 152997335 Common - diguanylate cyclase Mmwyl1_3330 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994742 Common - SEC-C motif domain protein Mmwyl1_0708 31 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 152997747 Common - prolipoprotein diacylglyceryl transferase Mmwyl1_3746 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 152994388 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0350 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152994453 Nonpathogen - GCN5-related N-acetyltransferase Mmwyl1_0415 6 COG0456 RimI, Acetyltransferases General function prediction only 152995293 Common - hypothetical protein Mmwyl1_1264 6 None None None 152996513 Common - GCN5-related N-acetyltransferase Mmwyl1_2493 48 None None None 152998243 Common - major facilitator superfamily MFS_1 Mmwyl1_4248 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994521 Common - transcriptional regulator, LysR family Mmwyl1_0484 114 COG0583 LysR, Transcriptional regulator Transcription 152994833 Common - NAD-dependent epimerase/dehydratase Mmwyl1_0799 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152995668 Nonpathogen - hypothetical protein Mmwyl1_1642 2 None None None 152998162 Common - aldehyde dehydrogenase Mmwyl1_4166 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994108 Common - globin Mmwyl1_0066 142 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 152995829 Common - hypothetical protein Mmwyl1_1805 8 None None None 152995804 Common - protein of unknown function DUF1568 Mmwyl1_1779 11 None None None 152995822 Common - protein of unknown function DUF6 transmembrane Mmwyl1_1798 60 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152994296 Common - monofunctional biosynthetic peptidoglycan transglycosylase Mmwyl1_0254 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 152997538 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_3535 109 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152998455 Nonpathogen - transcriptional regulator, TrmB Mmwyl1_4460 8 COG1378 COG1378, Predicted transcriptional regulators Transcription 152994253 Common - Transcriptional regulator IclR Mmwyl1_0211 117 COG1414 IclR, Transcriptional regulator Transcription 152998387 Common - putative transcriptional regulator, AsnC family Mmwyl1_4392 152 COG1522 Lrp, Transcriptional regulators Transcription 152994126 Common - major facilitator superfamily MFS_1 Mmwyl1_0084 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996087 Common - lipase class 3 Mmwyl1_2065 16 COG3675 COG3675, Predicted lipase Lipid metabolism 152994046 Common - DNA replication and repair protein RecF Mmwyl1_0003 167 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 152998204 Nonpathogen - hypothetical protein Mmwyl1_4208 1 None None None 152994563 Common - Peptidoglycan-binding LysM Mmwyl1_0527 18 COG3673 COG3673, Uncharacterized conserved protein Function unknown 152996481 Common - CBS domain containing protein Mmwyl1_2459 15 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 152996612 Common - hypothetical protein Mmwyl1_2599 2 None None None 152994559 Common - transcriptional regulator, TetR family Mmwyl1_0523 39 COG1309 AcrR, Transcriptional regulator Transcription 152994584 Common - pantetheine-phosphate adenylyltransferase Mmwyl1_0548 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 152995019 Common - transglutaminase domain protein Mmwyl1_0988 78 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 152996137 Nonpathogen - hypothetical protein Mmwyl1_2115 1 None None None 152997401 Common - YCII-related Mmwyl1_3398 70 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 152997493 Common - Integrase catalytic region Mmwyl1_3490 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997541 Common - Pirin domain protein Mmwyl1_3538 135 COG1741 COG1741, Pirin-related protein General function prediction only 152997957 Nonpathogen - hypothetical protein Mmwyl1_3960 1 None None None 152998430 Common - protein of unknown function DUF112 transmembrane Mmwyl1_4435 86 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152994367 Common - sodium:dicarboxylate symporter Mmwyl1_0327 157 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 152995642 Common - sugar (Glycoside-Pentoside-Hexuronide) transporter Mmwyl1_1614 89 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 152996964 Common - Integrase catalytic region Mmwyl1_2953 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152995458 Common - uracil-DNA glycosylase superfamily Mmwyl1_1429 59 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 152995223 Common - Rhs element Vgr protein Mmwyl1_1194 62 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 152997454 Common - PAS/PAC sensor signal transduction histidine kinase Mmwyl1_3451 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995740 Common - NADH:ubiquinone oxidoreductase, subunit D Mmwyl1_1714 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 152996780 Common - transcriptional regulator, LysR family Mmwyl1_2767 163 COG0583 LysR, Transcriptional regulator Transcription 152997001 Common - Diverse 7TM receptor extracellular region 2 Mmwyl1_2990 18 None None None 152998285 Common - Sporulation domain protein Mmwyl1_4290 4 None None None 152997930 Common - protein of unknown function DUF112 transmembrane Mmwyl1_3933 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152994635 Common - HNH endonuclease Mmwyl1_0601 22 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 152995931 Common - histidine kinase Mmwyl1_1907 225 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 152995906 Common - hypothetical protein Mmwyl1_1882 8 None None None 152998218 Common - hypothetical protein Mmwyl1_4223 3 None None None 152994182 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0140 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994695 Common - glutamine amidotransferase of anthranilate synthase Mmwyl1_0661 235 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 152998199 Common - transposase, IS4 Mmwyl1_4203 27 None None None 152996391 Common - ATP dependent DNA ligase Mmwyl1_2369 30 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 152996405 Common - integral membrane sensor hybrid histidine kinase Mmwyl1_2383 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996171 Common - ComEC/Rec2-related protein Mmwyl1_2149 127 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 152995621 Common - oxidoreductase domain protein Mmwyl1_1593 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152997556 Common - DNA topoisomerase IV, B subunit Mmwyl1_3554 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 152996788 Common - Helix-turn-helix type 11 domain protein Mmwyl1_2775 101 COG2378 COG2378, Predicted transcriptional regulator Transcription 152996721 Common - hypothetical protein Mmwyl1_2708 49 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 152997772 Common - signal recognition particle protein Mmwyl1_3771 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 152994945 Common - multi-sensor signal transduction histidine kinase Mmwyl1_0914 160 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 152997840 Common - major facilitator superfamily MFS_1 Mmwyl1_3841 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994508 Common - transcriptional regulator, GntR family Mmwyl1_0471 123 COG1802 GntR, Transcriptional regulators Transcription 152994417 Common - ABC transporter related Mmwyl1_0379 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152997527 Common - Glutamate--putrescine ligase Mmwyl1_3524 230 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 152997072 Common - filamentous haemagglutinin family outer membrane protein Mmwyl1_3062 157 None None None 152998156 Common - TRAP transporter solute receptor, TAXI family Mmwyl1_4160 86 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 152994978 Common - hypothetical protein Mmwyl1_0947 9 None None None 152994933 Nonpathogen - hypothetical protein Mmwyl1_0901 2 None None None 152998294 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mmwyl1_4299 68 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 152996396 Common - Caffeoyl-CoA O-methyltransferase Mmwyl1_2374 94 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 152994074 Common - Beta-ketoacyl synthase Mmwyl1_0031 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152995014 Common - hypothetical protein Mmwyl1_0983 3 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152995811 Common - site-specific recombinase, phage integrase family Mmwyl1_1786 65 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152996599 Common - putative transposase Mmwyl1_2585 71 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152996381 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_2359 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 152997090 Common - tartrate dehydrogenase Mmwyl1_3080 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 152997195 Common - Uncharacterized protein UPF0065 Mmwyl1_3187 52 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152994721 Nonpathogen - hypothetical protein Mmwyl1_0687 1 None None None 152996141 Common - DEAD/DEAH box helicase domain protein Mmwyl1_2119 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152997552 Common - hypothetical protein Mmwyl1_3550 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 152994092 Common - TonB-dependent siderophore receptor Mmwyl1_0049 127 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 152997974 Common - DNA binding domain, excisionase family Mmwyl1_3978 31 None None None 152998050 Common - Abi family protein Mmwyl1_4054 35 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 152996996 Common - putative TIM-barrel protein, nifR3 family Mmwyl1_2985 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 152998457 Common - ATP synthase F1, beta subunit Mmwyl1_4462 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 152995035 Common - nitroreductase Mmwyl1_1004 103 COG0778 NfnB, Nitroreductase Energy production and conversion 152996834 Common - response regulator receiver protein Mmwyl1_2822 142 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997408 Common - DNA ligase, NAD-dependent Mmwyl1_3405 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 152994956 Common - methylisocitrate lyase Mmwyl1_0925 136 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 152998461 Common - ATP synthase F0, B subunit Mmwyl1_4466 149 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 152995885 Common - Xylose isomerase domain protein TIM barrel Mmwyl1_1861 53 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 152994048 Common - NmrA family protein Mmwyl1_0005 98 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152994596 Common - KilA domain protein Mmwyl1_0561 15 None None None 152996621 Common - UDP-3-0-acyl N-acetylglucosamine deacetylase Mmwyl1_2608 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 152994769 Common - signal transduction histidine kinase, nitrogen specific, NtrB Mmwyl1_0735 210 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 152997031 Common - Enoyl-CoA hydratase/isomerase Mmwyl1_3020 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 152994369 Common - major facilitator superfamily MFS_1 Mmwyl1_0331 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152997172 Common - Uncharacterized protein UPF0065 Mmwyl1_3164 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152995966 Common - membrane protein-like protein Mmwyl1_1942 55 COG3164 COG3164, Predicted membrane protein Function unknown 152996682 Common - Rieske (2Fe-2S) domain protein Mmwyl1_2669 80 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 152998226 Common - riboflavin biosynthesis protein RibF Mmwyl1_4231 211 COG0196 RibF, FAD synthase Coenzyme metabolism 152994543 Common - transcriptional regulator, LysR family Mmwyl1_0507 77 COG0583 LysR, Transcriptional regulator Transcription 152995908 Common - hypothetical protein Mmwyl1_1884 15 None None None 152996262 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mmwyl1_2240 185 COG0546 Gph, Predicted phosphatases General function prediction only 152995598 Common - cobalamin synthesis protein P47K Mmwyl1_1570 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 152997851 Common - abortive infection protein Mmwyl1_3852 26 COG1106 COG1106, Predicted ATPases General function prediction only 152995114 Common - aminoglycoside phosphotransferase Mmwyl1_1083 27 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 152997379 Common - Precorrin-8X methylmutase Mmwyl1_3376 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 152998466 Common - Cobyrinic acid ac-diamide synthase Mmwyl1_4471 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 152997149 Common - monooxygenase FAD-binding Mmwyl1_3140 73 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152994319 Nonpathogen - hypothetical protein Mmwyl1_0278 1 None None None 152994863 Common - WbqC-like family protein Mmwyl1_0831 38 None None None 152997435 Common - flagellar biosynthetic protein FliR Mmwyl1_3432 120 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 152997374 Nonpathogen - hypothetical protein Mmwyl1_3371 1 None None None 152996383 Common - aminoacyl-histidine dipeptidase Mmwyl1_2361 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 152995901 Common - hypothetical protein Mmwyl1_1877 18 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 152996324 Common - anion transporter Mmwyl1_2302 74 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 152994940 Common - Alcohol dehydrogenase zinc-binding domain protein Mmwyl1_0909 168 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 152994116 Common - Porphobilinogen synthase Mmwyl1_0074 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 152997460 Common - biotin synthase Mmwyl1_3457 180 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 152995102 Common - tyrosyl-tRNA synthetase Mmwyl1_1071 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152995861 Common - amino acid permease-associated region Mmwyl1_1837 133 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 152994399 Common - LamB/YcsF family protein Mmwyl1_0361 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 152995751 Common - ATP-dependent protease La Mmwyl1_1725 218 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 152996903 Common - protein of unknown function UPF0029 Mmwyl1_2891 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 152997381 Common - cobalamin biosynthesis protein CbiD Mmwyl1_3378 79 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 152996896 Common - Aspartyl aminopeptidase Mmwyl1_2884 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 152995845 Common - inner-membrane translocator Mmwyl1_1821 135 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 152996790 Common - pentapeptide repeat protein Mmwyl1_2777 33 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 152994842 Common - Alcohol dehydrogenase zinc-binding domain protein Mmwyl1_0808 197 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152996146 Common - alpha/beta hydrolase fold Mmwyl1_2124 108 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152996299 Common - NAD(P) transhydrogenase, alpha subunit Mmwyl1_2277 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 152996656 Common - phosphatidylserine decarboxylase Mmwyl1_2643 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 152997135 Common - glycosyl transferase, family 2 Mmwyl1_3125 64 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 152996099 Common - heat shock protein DnaJ domain protein Mmwyl1_2077 131 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 152997645 Common - diacylglycerol kinase Mmwyl1_3643 68 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 152995184 Common - putative transcriptional regulator, MerR family Mmwyl1_1155 35 COG0789 SoxR, Predicted transcriptional regulators Transcription 152997657 Common - nitrogen regulatory protein P-II Mmwyl1_3656 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 152997184 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Mmwyl1_3176 161 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152998354 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Mmwyl1_4359 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152995617 Common - transcriptional regulator, RpiR family Mmwyl1_1589 95 COG1737 RpiR, Transcriptional regulators Transcription 152996491 Common - putative prophage repressor Mmwyl1_2469 55 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 152994758 Common - peptidase M23B Mmwyl1_0724 184 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 152995868 Common - Threonine aldolase Mmwyl1_1844 112 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 152995549 Common - AzlC family protein Mmwyl1_1521 111 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 152997060 Common - alpha/beta hydrolase fold Mmwyl1_3049 167 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152998440 Common - Aspartate transaminase Mmwyl1_4445 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152995638 Common - hypothetical protein Mmwyl1_1610 5 None None None 152996033 Common - glycoside hydrolase clan GH-D Mmwyl1_2011 42 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 152996645 Common - RNA chaperone Hfq Mmwyl1_2632 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 152998016 Nonpathogen - hypothetical protein Mmwyl1_4020 4 None None None 152995527 Common - hypothetical protein Mmwyl1_1499 8 None None None 152995350 Common - putative transcriptional regulator, AsnC family Mmwyl1_1321 154 COG1522 Lrp, Transcriptional regulators Transcription 152994390 Common - hypothetical protein Mmwyl1_0352 14 None None None 152994797 Common - WD-40 repeat protein Mmwyl1_0763 39 COG2319 COG2319, FOG: WD40 repeat General function prediction only 152997317 Nonpathogen - hypothetical protein Mmwyl1_3312 1 None None None 152994815 Common - Ribose/galactose isomerase Mmwyl1_0781 22 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 152996105 Nonpathogen - hypothetical protein Mmwyl1_2083 1 None None None 152995830 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_1806 123 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996091 Common - Alcohol dehydrogenase zinc-binding domain protein Mmwyl1_2069 175 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 152997269 Common - NUDIX hydrolase Mmwyl1_3264 45 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 152997117 Common - PfkB domain protein Mmwyl1_3107 170 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 152998166 Common - Monosaccharide-transporting ATPase Mmwyl1_4170 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152997618 Common - hypothetical protein Mmwyl1_3616 28 COG3148 COG3148, Uncharacterized conserved protein Function unknown 152996164 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Mmwyl1_2142 224 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 152994158 Common - lipolytic protein G-D-S-L family Mmwyl1_0116 14 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 152996764 Common - Carboxypeptidase Taq Mmwyl1_2751 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 152998116 Nonpathogen - hypothetical protein Mmwyl1_4120 1 None None None 152995993 Common - putative NAD(P) transhydrogenase alpha-2 subunit Mmwyl1_1969 56 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 152994981 Common - inner-membrane translocator Mmwyl1_0950 161 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 152994085 Common - Malate/L-lactate dehydrogenase Mmwyl1_0042 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 152996373 Common - Di-haem cytochrome c peroxidase Mmwyl1_2351 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 152996726 Common - ABC transporter related Mmwyl1_2713 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152998088 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_4092 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152997231 Common - thioredoxin reductase Mmwyl1_3225 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 152996823 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Mmwyl1_2811 85 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 152997882 Common - hypothetical protein Mmwyl1_3884 3 None None None 152994358 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mmwyl1_0318 93 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 152994831 Common - RNA-metabolising metallo-beta-lactamase Mmwyl1_0797 127 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 152996365 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Mmwyl1_2343 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 152994515 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0478 87 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995289 Common - SlyX family protein Mmwyl1_1260 12 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 152995193 Common - HupE/UreJ protein Mmwyl1_1164 46 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 152995499 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_1470 82 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152997584 Common - flagellar basal-body rod protein FlgC Mmwyl1_3582 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 152994284 Common - diacylglycerol kinase catalytic region Mmwyl1_0242 105 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 152994698 Common - hypothetical protein Mmwyl1_0664 22 COG4683 COG4683, Uncharacterized protein conserved in bacteria Function unknown 152994212 Common - transcriptional regulator, AraC family Mmwyl1_0170 140 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152995321 Common - Fusaric acid resistance protein conserved region Mmwyl1_1292 41 COG1289 COG1289, Predicted membrane protein Function unknown 152996485 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_2463 20 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152995448 Common - short chain fatty acid transporter Mmwyl1_1419 43 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 152996555 Common - 2OG-Fe(II) oxygenase Mmwyl1_2536 30 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 152997603 Common - Tetratricopeptide TPR_2 repeat protein Mmwyl1_3601 97 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 152996676 Common - glycosyl transferase family 39 Mmwyl1_2663 97 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 152994483 Common - ABC transporter related Mmwyl1_0446 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152994671 Common - putative ammonia monooxygenase Mmwyl1_0637 46 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 152995680 Common - N-acetylglucosamine-6-phosphate deacetylase Mmwyl1_1654 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 152997627 Common - dihydrouridine synthase DuS Mmwyl1_3625 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 152997982 Common - multiple resistance and pH regulation protein F Mmwyl1_3986 69 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 152996628 Common - cell division protein FtsW Mmwyl1_2615 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 152996006 Common - putative transcriptional regulator Mmwyl1_1983 37 COG3636 COG3636, Predicted transcriptional regulator Transcription 152996646 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Mmwyl1_2633 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 152996421 Common - ribosomal protein S9 Mmwyl1_2399 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 152997994 Common - Porphobilinogen synthase Mmwyl1_3998 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 152995088 Common - Ribulose-phosphate 3-epimerase Mmwyl1_1057 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 152996582 Common - Integrase catalytic region Mmwyl1_2563 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997999 Common - CBS domain containing protein Mmwyl1_4003 131 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 152995516 Common - Protoporphyrinogen oxidase Mmwyl1_1487 35 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 152996295 Nonpathogen - hypothetical protein Mmwyl1_2273 1 None None None 152995312 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Mmwyl1_1283 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 152998221 Common - hypothetical protein Mmwyl1_4226 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 152994972 Common - Helix-turn-helix type 11 domain protein Mmwyl1_0941 107 COG2378 COG2378, Predicted transcriptional regulator Transcription 152996279 Common - NADH dehydrogenase Mmwyl1_2257 179 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 152996704 Nonpathogen - hypothetical protein Mmwyl1_2691 9 COG1769 COG1769, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 152995335 Common - protein of unknown function DUF368 Mmwyl1_1306 50 COG2035 COG2035, Predicted membrane protein Function unknown 152997823 Common - extracellular solute-binding protein family 5 Mmwyl1_3824 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152995614 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1586 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998184 Common - Monosaccharide-transporting ATPase Mmwyl1_4188 157 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152996001 Common - uncharacterized conserved coiled coil protein Mmwyl1_1978 24 None None None 152994660 Common - Integrase catalytic region Mmwyl1_0626 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152996830 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2818 147 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 152998411 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4416 222 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 152998400 Common - Alkaline phosphatase Mmwyl1_4405 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152997674 Nonpathogen - hypothetical protein Mmwyl1_3673 7 None None None 152997050 Common - putative protein-disulfide isomerase Mmwyl1_3039 33 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 152996876 Nonpathogen - hypothetical protein Mmwyl1_2864 1 None None None 152996253 Nonpathogen - YfaZ family protein Mmwyl1_2231 3 None None None 152994606 Common - hypothetical protein Mmwyl1_0571 12 None None None 152997738 Common - dihydroxy-acid dehydratase Mmwyl1_3737 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 152997363 Nonpathogen - hypothetical protein Mmwyl1_3359 1 None None None 152996540 Common - hypothetical protein Mmwyl1_2521 6 None None None 152997345 Common - carbon starvation protein CstA Mmwyl1_3340 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 152998263 Common - ribosomal protein L29 Mmwyl1_4268 131 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 152994286 Common - major facilitator superfamily MFS_1 Mmwyl1_0244 25 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994342 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_0301 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997254 Common - putative sulfur oxidation protein DsrF Mmwyl1_3248 7 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 152994710 Common - histidine kinase Mmwyl1_0676 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996882 Common - phospholipid/glycerol acyltransferase Mmwyl1_2870 30 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 152997162 Common - cytochrome bd ubiquinol oxidase subunit I Mmwyl1_3153 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 152994898 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Mmwyl1_0866 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152996461 Common - ABC transporter, fused inner membrane subunits Mmwyl1_2439 45 COG4135 COG4135, ABC-type uncharacterized transport system, permease component General function prediction only 152996318 Nonpathogen - hypothetical protein Mmwyl1_2296 1 None None None 152996590 Common - AMP-dependent synthetase and ligase Mmwyl1_2573 208 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152997948 Common - protein of unknown function DUF501 Mmwyl1_3951 27 COG1507 COG1507, Uncharacterized conserved protein Function unknown 152994708 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_0674 157 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 152996731 Common - periplasmic binding protein Mmwyl1_2718 104 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 152994196 Common - GCN5-related N-acetyltransferase Mmwyl1_0154 25 COG0456 RimI, Acetyltransferases General function prediction only 152994339 Common - Membrane-fusion protein-like protein Mmwyl1_0298 130 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152995731 Common - DNA polymerase III, epsilon subunit Mmwyl1_1705 190 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 152995714 Common - GTP-binding protein HSR1-related Mmwyl1_1688 103 COG1161 COG1161, Predicted GTPases General function prediction only 152995270 Common - glycogen/starch synthase, ADP-glucose type Mmwyl1_1241 151 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 152995423 Common - heat shock protein DnaJ domain protein Mmwyl1_1394 2 None None None 152994915 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0883 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152998370 Common - hypothetical protein Mmwyl1_4375 2 None None None 152997890 Common - heat shock protein Hsp20 Mmwyl1_3892 83 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 152997019 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mmwyl1_3008 57 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 152994463 Common - dienelactone hydrolase Mmwyl1_0425 46 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 152998393 Common - Chorismate lyase Mmwyl1_4398 41 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 152994538 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0502 31 COG2962 RarD, Predicted permeases General function prediction only 152995315 Common - Ribonuclease H Mmwyl1_1286 240 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 152997428 Common - CheA signal transduction histidine kinase Mmwyl1_3425 155 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 152996215 Common - Tol-Pal system TolA Mmwyl1_2193 8 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 152997127 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_3117 54 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152995608 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_1580 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 152995200 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1171 124 COG1609 PurR, Transcriptional regulators Transcription 152998249 Common - ribosomal protein S13 Mmwyl1_4254 238 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 152995532 Common - phospholipid/glycerol acyltransferase Mmwyl1_1504 45 COG3176 COG3176, Putative hemolysin General function prediction only 152994736 Nonpathogen - hypothetical protein Mmwyl1_0702 1 None None None 152996069 Common - Colicin V production protein Mmwyl1_2047 117 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 152994201 Nonpathogen - metallophosphoesterase Mmwyl1_0159 3 None None None 152994479 Common - flavin-containing monooxygenase FMO Mmwyl1_0442 64 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 152996196 Common - MOSC domain containing protein Mmwyl1_2174 53 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 152997489 Common - hemolysin A Mmwyl1_3486 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 152997856 Common - CitB domain protein Mmwyl1_3857 19 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 152996549 Common - protein of unknown function DUF709 Mmwyl1_2530 33 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 152996750 Common - 4-hydroxyphenylpyruvate dioxygenase Mmwyl1_2737 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 152995910 Common - monooxygenase FAD-binding Mmwyl1_1886 42 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152996559 Common - DTW domain containing protein Mmwyl1_2540 30 COG3148 COG3148, Uncharacterized conserved protein Function unknown 152994908 Common - transcriptional regulator, TetR family Mmwyl1_0876 81 COG1309 AcrR, Transcriptional regulator Transcription 152996661 Common - S-adenosylmethionine--tRNA-ribosyltransferase-isomerase Mmwyl1_2648 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 152998002 Nonpathogen - hypothetical protein Mmwyl1_4006 1 None None None 152995774 Common - plasmid stabilization system Mmwyl1_1748 24 COG3668 ParE, Plasmid stabilization system protein General function prediction only 152994372 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0334 149 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152994144 Common - acyltransferase 3 Mmwyl1_0102 17 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 152997634 Nonpathogen - putative sigma 54 modulation protein/ribosomal protein S30EA Mmwyl1_3632 6 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 152994332 Common - high-affinity nickel-transporter Mmwyl1_0291 38 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 152995948 Common - inner-membrane translocator Mmwyl1_1924 157 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 152995328 Common - Phosphopyruvate hydratase Mmwyl1_1299 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 152994726 Common - transport system permease protein Mmwyl1_0692 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152996290 Common - aminodeoxychorismate lyase Mmwyl1_2268 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 152996689 Common - fumarylacetoacetate (FAA) hydrolase Mmwyl1_2676 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152997520 Common - Glutamate--putrescine ligase Mmwyl1_3517 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 152995136 Common - adenylate cyclase Mmwyl1_1105 54 COG3025 COG3025, Uncharacterized conserved protein Function unknown 152995850 Common - Rieske (2Fe-2S) domain protein Mmwyl1_1826 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 152994701 Common - hypothetical protein Mmwyl1_0667 9 COG4902 COG4902, Uncharacterized protein conserved in archaea Function unknown 152996748 Common - fumarylacetoacetase Mmwyl1_2735 57 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152995363 Common - transcriptional regulator, LysR family Mmwyl1_1334 174 COG0583 LysR, Transcriptional regulator Transcription 152995259 Common - GCN5-related N-acetyltransferase Mmwyl1_1230 33 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 152995568 Common - electron transport complex, RnfABCDGE type, E subunit Mmwyl1_1540 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 152994237 Common - hypothetical protein Mmwyl1_0195 5 None None None 152998139 Common - transcriptional regulator, LysR family Mmwyl1_4143 103 COG0583 LysR, Transcriptional regulator Transcription 152997192 Common - hypothetical protein Mmwyl1_3184 2 None None None 152995277 Common - DNA repair protein RecO Mmwyl1_1248 55 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 152997413 Common - cytochrome c-type biogenesis protein CcmF Mmwyl1_3410 148 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 152996228 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_2206 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 152996357 Nonpathogen - hypothetical protein Mmwyl1_2335 1 None None None 152996438 Common - Cell envelope biogenesis YhbN Mmwyl1_2416 52 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 152995595 Common - GumN family protein Mmwyl1_1567 51 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 152995207 Common - transcriptional regulator, XRE family Mmwyl1_1178 6 COG1396 HipB, Predicted transcriptional regulators Transcription 152998342 Common - two component transcriptional regulator, winged helix family Mmwyl1_4347 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152995378 Common - protein of unknown function DUF59 Mmwyl1_1349 137 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 152996152 Common - fatty acid synthesis plsX protein Mmwyl1_2130 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 152995770 Common - transposase IS4 family protein Mmwyl1_1744 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 152994870 Common - glucose-1-phosphate thymidylyltransferase Mmwyl1_0838 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 152994892 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0860 60 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152997607 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Mmwyl1_3605 191 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 152997965 Common - SmpA/OmlA domain protein Mmwyl1_3968 63 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 152997816 Common - hypothetical protein Mmwyl1_3817 6 None None None 152995149 Common - uroporphyrinogen decarboxylase Mmwyl1_1118 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 152998025 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_4029 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995756 Common - Dyp-type peroxidase family Mmwyl1_1730 51 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 152997107 Common - beta-ketoadipyl CoA thiolase Mmwyl1_3097 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152995488 Common - hypothetical protein Mmwyl1_1459 32 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 152995237 Common - ImpA domain protein Mmwyl1_1208 19 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 152994646 Common - Transcriptional regulator IclR Mmwyl1_0612 121 COG1414 IclR, Transcriptional regulator Transcription 152997218 Common - inner-membrane translocator Mmwyl1_3210 147 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 152998005 Common - permease YjgP/YjgQ family protein Mmwyl1_4009 117 COG0795 COG0795, Predicted permeases General function prediction only 152994051 Common - TonB-dependent siderophore receptor Mmwyl1_0008 124 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 152994961 Common - oxidoreductase, short-chain dehydrogenase/reductase family protein Mmwyl1_0930 54 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152995460 Common - phenazine biosynthesis protein PhzF family Mmwyl1_1431 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 152998409 Common - phosphate ABC transporter, ATPase subunit Mmwyl1_4414 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 152996828 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mmwyl1_2816 197 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 152995511 Common - sodium/sulphate symporter Mmwyl1_1482 76 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 152998449 Common - ABC transporter related Mmwyl1_4454 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 152995266 Common - metal dependent phosphohydrolase Mmwyl1_1237 62 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 152994185 Common - hypothetical protein Mmwyl1_0143 4 None None None 152997276 Common - transcriptional regulator, LysR family Mmwyl1_3271 138 COG0583 LysR, Transcriptional regulator Transcription 152994474 Common - GCN5-related N-acetyltransferase Mmwyl1_0437 85 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 152994901 Common - beta-lactamase domain protein Mmwyl1_0869 183 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 152995046 Common - efflux transporter, RND family, MFP subunit Mmwyl1_1015 156 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152995269 Common - extracellular solute-binding protein family 3 Mmwyl1_1240 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152995313 Common - acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase Mmwyl1_1284 165 COG1043 LpxA, Acyl- acyl carrier protein 152996864 Common - gamma-glutamyl phosphate reductase Mmwyl1_2852 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 152994889 Common - hypothetical protein Mmwyl1_0857 6 None None None 152995384 Common - hypothetical protein Mmwyl1_1355 42 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 152995866 Common - GCN5-related N-acetyltransferase Mmwyl1_1842 113 COG0456 RimI, Acetyltransferases General function prediction only 152997543 Common - CRISPR-associated protein Cas2 Mmwyl1_3540 29 None None None 152996743 Common - tRNA synthetase class II (G H P and S) Mmwyl1_2730 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152996825 Common - molybdopterin oxidoreductase Mmwyl1_2813 194 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 152996931 Common - conserved protein/domain typically associated with flavoprotein oxygenase, DIM6/NTAB family Mmwyl1_2920 71 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 152994582 Common - pyrroline-5-carboxylate reductase Mmwyl1_0546 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 152995946 Common - adenosine deaminase Mmwyl1_1922 100 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 152996960 Nonpathogen - hypothetical protein Mmwyl1_2949 1 None None None 152997423 Common - CheW domain protein Mmwyl1_3420 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 152995552 Common - thioredoxin Mmwyl1_1524 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 152997088 Common - GCN5-related N-acetyltransferase Mmwyl1_3078 20 None None None 152996579 Common - uncharacterised conserved protein UCP028101 Mmwyl1_2560 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 152997351 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3346 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998231 Common - GTP-binding protein Obg/CgtA Mmwyl1_4236 249 COG0536 Obg, Predicted GTPase General function prediction only 152997658 Common - ammonium transporter Mmwyl1_3657 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 152998034 Nonpathogen - hypothetical protein Mmwyl1_4038 1 None None None 152996026 Common - secretion protein HlyD family protein Mmwyl1_2004 155 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 152995240 Common - protein of unknown function DUF796 Mmwyl1_1211 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 152995984 Common - H+transporting two-sector ATPase B/B' subunit Mmwyl1_1960 54 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 152998283 Common - NusG antitermination factor Mmwyl1_4288 215 COG0250 NusG, Transcription antiterminator Transcription 152997563 Common - DegT/DnrJ/EryC1/StrS aminotransferase Mmwyl1_3561 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 152997928 Common - Uncharacterized protein UPF0065 Mmwyl1_3931 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152997573 Common - flagellin domain protein Mmwyl1_3571 124 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 152996017 Common - putative transcriptional regulator, MerR family Mmwyl1_1995 93 COG0789 SoxR, Predicted transcriptional regulators Transcription 152994230 Common - protein of unknown function DUF45 Mmwyl1_0188 42 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 152996938 Common - Tannase and feruloyl esterase Mmwyl1_2927 20 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 152998158 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4162 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997253 Common - DsrE family protein Mmwyl1_3247 42 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 152995732 Common - Na+ antiporter NhaB Mmwyl1_1706 25 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 152995353 Common - quorum-sensing autoinducer 2 (AI-2), LuxS Mmwyl1_1324 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 152997164 Common - uncharacterised conserved protein UCP030820 Mmwyl1_3155 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 152996055 Common - protein of unknown function DUF520 Mmwyl1_2033 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 152994468 Common - HPP family protein? Mmwyl1_0430 68 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 152994849 Common - UDP-glucose 4-epimerase Mmwyl1_0816 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 152996072 Common - acriflavin resistance protein Mmwyl1_2050 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 152996553 Common - DNA polymerase III, subunits gamma and tau Mmwyl1_2534 245 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 152997609 Common - GTP-binding protein YchF Mmwyl1_3607 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 152998066 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mmwyl1_4070 127 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 152997282 Nonpathogen - hypothetical protein Mmwyl1_3277 4 None None None 152998192 Common - transcriptional regulator Mmwyl1_4196 40 COG2378 COG2378, Predicted transcriptional regulator Transcription 152997721 Common - FAD dependent oxidoreductase Mmwyl1_3720 55 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 152995462 Common - protein of unknown function DUF962 Mmwyl1_1433 27 COG4539 COG4539, Predicted membrane protein Function unknown 152996005 Common - DNA-directed DNA polymerase Mmwyl1_1982 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 152997567 Common - hypothetical protein Mmwyl1_3565 16 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 152994402 Common - HI0933 family protein Mmwyl1_0364 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 152997323 Common - hypothetical protein Mmwyl1_3318 3 None None None 152995163 Common - YbaK/prolyl-tRNA synthetase associated region Mmwyl1_1134 29 COG3760 COG3760, Uncharacterized conserved protein Function unknown 152994719 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0685 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998056 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Mmwyl1_4060 102 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 152994650 Common - protein of unknown function DUF785 Mmwyl1_0616 38 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 152994161 Common - transcriptional regulator, DeoR family Mmwyl1_0119 114 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 152994472 Nonpathogen - hypothetical protein Mmwyl1_0435 1 None None None 152996928 Common - DNA polymerase III, delta subunit Mmwyl1_2917 86 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 152994053 Common - major facilitator superfamily MFS_1 Mmwyl1_0010 39 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 152997439 Common - flagellar motor switch protein FliN Mmwyl1_3436 121 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 152996884 Common - two component transcriptional regulator, winged helix family Mmwyl1_2872 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152998078 Common - 5'-Nucleotidase domain protein Mmwyl1_4082 130 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 152995332 Common - tRNA pseudouridine synthase D TruD Mmwyl1_1303 85 COG0585 COG0585, Uncharacterized conserved protein Function unknown 152998276 Common - ribosomal protein S12 Mmwyl1_4281 243 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 152994808 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0774 171 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152994214 Common - Alcohol dehydrogenase Mmwyl1_0172 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 152996103 Common - molybdopterin biosynthesis MoaE protein Mmwyl1_2081 153 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 152997386 Common - protein of unknown function DUF161 Mmwyl1_3383 41 COG1284 COG1284, Uncharacterized conserved protein Function unknown 152995546 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_1518 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152994531 Common - Altronate dehydratase Mmwyl1_0495 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 152995842 Common - 2-dehydropantoate 2-reductase Mmwyl1_1818 108 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 152997294 Common - hypothetical protein Mmwyl1_3289 24 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 152994496 Common - FAD dependent oxidoreductase Mmwyl1_0459 102 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152998029 Common - transcription elongation factor GreA Mmwyl1_4033 204 COG0782 GreA, Transcription elongation factor Transcription 152995268 Common - Peptidoglycan glycosyltransferase Mmwyl1_1239 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 152998090 Common - extracellular solute-binding protein family 3 Mmwyl1_4094 126 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152994362 Common - hypothetical protein Mmwyl1_0322 5 None None None 152995895 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1871 100 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152998386 Nonpathogen - hypothetical protein Mmwyl1_4391 1 None None None 152995849 Common - hypothetical protein Mmwyl1_1825 11 None None None 152997008 Common - Ribonucleoside-diphosphate reductase Mmwyl1_2997 154 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 152997398 Common - Sua5/YciO/YrdC/YwlC family protein Mmwyl1_3395 198 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 152994657 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Mmwyl1_0623 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 152997102 Common - phenylacetate-CoA oxygenase, PaaJ subunit Mmwyl1_3092 57 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 152994099 Common - hypothetical protein Mmwyl1_0057 10 None None None 152994344 Common - Flp/Fap pilin component Mmwyl1_0303 4 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 152997052 Common - Muconolactone Delta-isomerase Mmwyl1_3041 24 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 152996850 Common - GCN5-related N-acetyltransferase Mmwyl1_2838 95 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152995176 Common - exodeoxyribonuclease VII, small subunit Mmwyl1_1147 108 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 152998405 Common - histidine kinase Mmwyl1_4410 186 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995593 Common - Methyltransferase type 11 Mmwyl1_1565 56 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152994506 Common - Chitin deacetylase Mmwyl1_0469 65 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 152995001 Common - Dicarboxylate carrier MatC domain protein Mmwyl1_0970 28 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 152997955 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Mmwyl1_3958 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 152994875 Common - O-antigen polymerase Mmwyl1_0843 8 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 152997370 Common - hypothetical protein Mmwyl1_3367 3 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 152995961 Common - cell shape determining protein, MreB/Mrl family Mmwyl1_1937 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 152995028 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mmwyl1_0997 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 152997642 Common - TonB-dependent siderophore receptor Mmwyl1_3640 122 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 152996984 Common - Integrase catalytic region Mmwyl1_2973 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997247 Common - excinuclease ABC, C subunit Mmwyl1_3241 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 152994323 Common - Helix-turn-helix type 11 domain protein Mmwyl1_0282 99 COG2378 COG2378, Predicted transcriptional regulator Transcription 152996064 Common - tryptophan synthase, beta subunit Mmwyl1_2042 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 152995503 Common - transcriptional regulator, LysR family Mmwyl1_1474 190 COG0583 LysR, Transcriptional regulator Transcription 152996449 Nonpathogen - hypothetical protein Mmwyl1_2427 1 None None None 152996993 Common - acetyl-CoA carboxylase, biotin carboxylase Mmwyl1_2982 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 152997714 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Mmwyl1_3713 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 152994101 Common - transcriptional regulator, TetR family Mmwyl1_0059 49 COG1309 AcrR, Transcriptional regulator Transcription 152994567 Common - hypothetical protein Mmwyl1_0531 2 None None None 152996025 Common - dienelactone hydrolase Mmwyl1_2003 41 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 152996695 Common - transcriptional regulator, LysR family Mmwyl1_2682 182 COG0583 LysR, Transcriptional regulator Transcription 152994303 Common - hypothetical protein Mmwyl1_0261 4 None None None 152997878 Common - 4-hydroxybenzoyl-CoA thioesterase domain protein Mmwyl1_3880 46 COG0824 FcbC, Predicted thioesterase General function prediction only 152997292 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_3287 223 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152995676 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1650 159 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152997784 Common - hypothetical protein Mmwyl1_3783 19 COG4240 COG4240, Predicted kinase General function prediction only 152996671 Common - GtrA family protein Mmwyl1_2658 14 COG2246 COG2246, Predicted membrane protein Function unknown 152995815 Common - preprotein translocase subunit SecA (ATPase, RNA helicase) Mmwyl1_1790 9 None None None 152995037 Common - TonB-dependent siderophore receptor Mmwyl1_1006 119 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 152996813 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein Mmwyl1_2801 184 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 152997884 Common - hypothetical protein Mmwyl1_3886 24 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 152996632 Common - UDP-N-acetylmuramyl-tripeptide synthetase Mmwyl1_2619 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 152994633 Nonpathogen - hypothetical protein Mmwyl1_0599 1 None None None 152997554 Common - Aspartate transaminase Mmwyl1_3552 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152996398 Common - dihydroorotase, homodimeric type Mmwyl1_2376 98 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 152998236 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA Mmwyl1_4241 83 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 152995291 Common - Redoxin domain protein Mmwyl1_1262 121 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 152997495 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_3492 125 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152994642 Common - Glycerophosphodiester phosphodiesterase Mmwyl1_0608 160 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 152995113 Common - transcriptional regulator, RpiR family Mmwyl1_1082 103 COG1737 RpiR, Transcriptional regulators Transcription 152998363 Common - hypothetical protein Mmwyl1_4368 6 None None None 152997304 Common - CheA signal transduction histidine kinase Mmwyl1_3299 158 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 152997804 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_3805 30 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152996762 Nonpathogen - hypothetical protein Mmwyl1_2749 1 None None None 152995416 Common - hypothetical protein Mmwyl1_1387 22 COG4129 COG4129, Predicted membrane protein Function unknown 152995225 Common - uncharacterised conserved protein UCP028301 Mmwyl1_1196 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 152994076 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0033 50 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152997886 Common - Beta-ketoacyl synthase Mmwyl1_3888 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152998041 Common dddR transcriptional regulator, LysR family Mmwyl1_4045 164 COG0583 LysR, Transcriptional regulator Transcription 152998216 Common - hypothetical protein Mmwyl1_4221 2 None None None 152996135 Nonpathogen - hypothetical protein Mmwyl1_2113 1 None None None 152995648 Common - transport system permease protein Mmwyl1_1620 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152997580 Common - flagellar basal-body rod protein FlgG Mmwyl1_3578 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 152997773 Common - cytochrome c assembly protein Mmwyl1_3772 80 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 152998335 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_4340 126 COG1609 PurR, Transcriptional regulators Transcription 152995391 Common - Succinylglutamate desuccinylase/aspartoacylase Mmwyl1_1362 55 COG3608 COG3608, Predicted deacylase General function prediction only 152997558 Common - protein of unknown function DUF1249 Mmwyl1_3556 24 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 152998436 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_4441 101 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152995367 Common - protein of unknown function UPF0153 Mmwyl1_1338 9 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 152994784 Common - glutamate--cysteine ligase Mmwyl1_0750 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 152994410 Nonpathogen - hypothetical protein Mmwyl1_0372 1 None None None 152997449 Common - flagellar assembly protein FliH Mmwyl1_3446 23 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 152996870 Common - chorismate mutase Mmwyl1_2858 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 152995483 Common - glycosyl transferase group 1 Mmwyl1_1454 180 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152994649 Common - diguanylate cyclase Mmwyl1_0615 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152998422 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_4427 133 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997442 Common - flagellar hook-length control protein Mmwyl1_3439 47 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 152994855 Common - oxidoreductase domain protein Mmwyl1_0822 105 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152995345 Common - Palmitoyl-CoA hydrolase Mmwyl1_1316 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 152997591 Nonpathogen - hypothetical protein Mmwyl1_3589 1 None None None 152996403 Common - SEC-C motif domain protein Mmwyl1_2381 97 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 152997598 Common - hypothetical protein Mmwyl1_3596 8 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 152998379 Common - Guanylate kinase Mmwyl1_4384 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 152994456 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_0418 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152994771 Common - thiamine biosynthesis/tRNA modification protein ThiI Mmwyl1_0737 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 152994861 Common - hypothetical protein Mmwyl1_0829 17 None None None 152995933 Common - amino acid carrier protein Mmwyl1_1909 113 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 152997266 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Mmwyl1_3260 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 152997470 Common - protein of unknown function DUF6 transmembrane Mmwyl1_3467 88 COG2962 RarD, Predicted permeases General function prediction only 152996994 Common - ribosomal protein L11 methyltransferase Mmwyl1_2983 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 152996836 Common - ABC transporter related Mmwyl1_2824 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 152998251 Common - preprotein translocase, SecY subunit Mmwyl1_4256 224 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 152996467 Common - hypothetical protein Mmwyl1_2445 21 None None None 152994315 Common - transcriptional regulator, LysR family Mmwyl1_0273 176 COG0583 LysR, Transcriptional regulator Transcription 152995691 Common - GCN5-related N-acetyltransferase Mmwyl1_1665 22 COG0456 RimI, Acetyltransferases General function prediction only 152997649 Common - Ribonuclease H Mmwyl1_3648 42 None None None 152994094 Common - proline racemase Mmwyl1_0052 48 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 152997638 Common - periplasmic binding protein Mmwyl1_3636 41 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 152995813 Common - putative transposase Mmwyl1_1788 31 None None None 152994947 Common - gamma-glutamyltransferase Mmwyl1_0916 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 152994123 Common - hypothetical protein Mmwyl1_0081 10 None None None 152995669 Nonpathogen - hypothetical protein Mmwyl1_1643 2 None None None 152997933 Common - cystathionine beta-lyase Mmwyl1_3936 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 152997369 Nonpathogen - hypothetical protein Mmwyl1_3365 1 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 152996971 Nonpathogen - hypothetical protein Mmwyl1_2960 1 None None None 152997197 Common - flavin reductase domain protein FMN-binding Mmwyl1_3189 126 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 152995282 Common - (p)ppGpp synthetase I, SpoT/RelA Mmwyl1_1253 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 152994124 Common - amino acid carrier protein Mmwyl1_0082 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 152996124 Common - UDP-2,3-diacylglucosamine hydrolase Mmwyl1_2102 72 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 152996794 Common - glycoside hydrolase family 31 Mmwyl1_2781 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 152998085 Common - MotA/TolQ/ExbB proton channel Mmwyl1_4089 19 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 152996945 Common - hypothetical protein Mmwyl1_2934 19 None None None 152997835 Common - hypothetical protein Mmwyl1_3836 37 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 152998376 Common - transcription activator effector binding Mmwyl1_4381 92 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 152994381 Common - TonB-dependent receptor plug Mmwyl1_0343 79 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 152995513 Common - major facilitator superfamily MFS_1 Mmwyl1_1484 166 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152997529 Common - FAD dependent oxidoreductase Mmwyl1_3526 128 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152994997 Common - sulfate ABC transporter, inner membrane subunit CysT Mmwyl1_0966 238 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 152997756 Common - putative signal transduction protein Mmwyl1_3755 65 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 152996303 Common - protein of unknown function DUF462 Mmwyl1_2281 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 152996237 Common - Ferrochelatase Mmwyl1_2215 161 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 152996601 Common - transposase Mmwyl1_2587 9 None None None 152996301 Nonpathogen - hypothetical protein Mmwyl1_2279 3 None None None 152995587 Common - hypothetical protein Mmwyl1_1559 4 None None None 152997536 Common - Monosaccharide-transporting ATPase Mmwyl1_3533 132 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152995802 Nonpathogen - hypothetical protein Mmwyl1_1776 3 None None None 152995703 Common - Guanine deaminase Mmwyl1_1677 161 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 152994916 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0884 174 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152996786 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2773 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994882 Common - MATE efflux family protein Mmwyl1_0850 139 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 152998112 Common - 3-dehydroquinate synthase Mmwyl1_4116 211 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 152996232 Common - DNA polymerase B region Mmwyl1_2210 66 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 152994938 Common - DoxX family protein Mmwyl1_0907 108 COG2259 COG2259, Predicted membrane protein Function unknown 152995782 Common - N-acylglucosamine 2-epimerase Mmwyl1_1756 49 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 152995492 Common - 1,4-alpha-glucan branching enzyme Mmwyl1_1463 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 152997779 Common - MscS Mechanosensitive ion channel Mmwyl1_3778 205 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 152995570 Common - electron transport complex, RnfABCDGE type, D subunit Mmwyl1_1542 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 152995871 Common - hypothetical protein Mmwyl1_1847 2 None None None 152995301 Common - ribosomal protein S2 Mmwyl1_1272 236 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 152995623 Common - thiamine pyrophosphate protein central region Mmwyl1_1595 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 152994971 Common - transcriptional regulator, LysR family Mmwyl1_0940 165 COG0583 LysR, Transcriptional regulator Transcription 152996818 Nonpathogen - hypothetical protein Mmwyl1_2806 1 None None None 152997112 Common - regulatory PhaM protein Mmwyl1_3102 199 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 152997701 Common - putative periplasmic ligand-binding sensor protein Mmwyl1_3700 16 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 152995398 Common - protein kinase Mmwyl1_1369 42 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 152994911 Common - hypothetical protein Mmwyl1_0879 16 COG2267 PldB, Lysophospholipase Lipid metabolism 152995303 Common - uridylate kinase Mmwyl1_1274 233 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 152996917 Common - metal dependent phosphohydrolase Mmwyl1_2906 56 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 152996185 Common - ATP-NAD/AcoX kinase Mmwyl1_2163 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 152994298 Common - hypothetical protein Mmwyl1_0256 9 None None None 152994115 Common - Acetyl-CoA C-acetyltransferase Mmwyl1_0073 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152994200 Nonpathogen - HPr kinase Mmwyl1_0158 3 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152998160 Common - protein of unknown function DUF6 transmembrane Mmwyl1_4164 89 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 152997476 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Mmwyl1_3473 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 152997241 Common - thioesterase superfamily protein Mmwyl1_3235 141 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 152997167 Common - Electron transfer flavoprotein alpha subunit Mmwyl1_3159 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 152997337 Common - chaperone DnaJ domain protein Mmwyl1_3332 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 152994345 Common - peptidase A24A prepilin type IV Mmwyl1_0304 23 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 152994747 Common - hypothetical protein Mmwyl1_0713 23 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 152998322 Common - cell division ATP-binding protein FtsE Mmwyl1_4327 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 152995765 Common - putative RNA methylase Mmwyl1_1739 157 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 152995717 Common - fatty acid cistrans isomerase Mmwyl1_1691 15 None None None 152996414 Common - thiamine biosynthesis protein ThiC Mmwyl1_2392 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 152996308 Common - transcriptional regulator, LysR family Mmwyl1_2286 182 COG0583 LysR, Transcriptional regulator Transcription 152995247 Common - hypothetical protein Mmwyl1_1218 4 None None None 152994360 Common - Oligopeptidase A Mmwyl1_0320 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 152997805 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_3806 114 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152995213 Nonpathogen - hypothetical protein Mmwyl1_1184 2 None None None 152996314 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_2292 80 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152994740 Common - transcriptional regulator, AraC family Mmwyl1_0706 90 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994326 Common - ABC-type uncharacterized transport system periplasmic component-like protein Mmwyl1_0285 8 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 152997749 Common - NUDIX hydrolase Mmwyl1_3748 116 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 152994273 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0231 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152995057 Common - NusA antitermination factor Mmwyl1_1026 216 COG0195 NusA, Transcription elongation factor Transcription 152996654 Common - flagellar motor component Mmwyl1_2641 109 COG1291 MotA, Flagellar motor component Cell motility and secretion 152995295 Common - succinyl-diaminopimelate desuccinylase Mmwyl1_1266 215 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152998415 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like protein Mmwyl1_4420 66 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 152997673 Common - hypothetical protein Mmwyl1_3672 10 None None None 152995093 Common - anthranilate phosphoribosyltransferase Mmwyl1_1062 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 152995729 Common - SAM-dependent methyltransferase Mmwyl1_1703 67 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152998118 Common - conserved hypothetical protein 730 Mmwyl1_4122 119 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 152997124 Common - transcriptional regulator, DeoR family Mmwyl1_3114 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 152997214 Common - Amidase Mmwyl1_3206 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152998141 Common - AAA ATPase central domain protein Mmwyl1_4145 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 152996521 Common - Phage regulatory protein Rha family Mmwyl1_2502 24 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 152995686 Common - hypothetical protein Mmwyl1_1660 23 None None None 152997975 Nonpathogen - hypothetical protein Mmwyl1_3979 2 None None None 152997589 Common - Diaminopimelate epimerase Mmwyl1_3587 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 152996045 Common - response regulator receiver modulated diguanylate cyclase Mmwyl1_2023 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152998173 Common - major facilitator superfamily MFS_1 Mmwyl1_4177 31 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 152994572 Common - oxidoreductase domain protein Mmwyl1_0536 185 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152997849 Common - prevent-host-death family protein Mmwyl1_3850 25 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 152994294 Common - transport system permease protein Mmwyl1_0252 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152998332 Common - protein of unknown function UPF0016 Mmwyl1_4337 75 COG2119 COG2119, Predicted membrane protein Function unknown 152996853 Common - lipoic acid synthetase Mmwyl1_2841 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 152998119 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) Mmwyl1_4123 202 COG0281 SfcA, Malic enzyme Energy production and conversion 152998314 Common - transketolase Mmwyl1_4319 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 152998459 Common - ATP synthase F1, alpha subunit Mmwyl1_4464 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 152997858 Common - transcriptional regulator, LysR family Mmwyl1_3859 181 COG0583 LysR, Transcriptional regulator Transcription 152995352 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_1323 82 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152994465 Common - protein of unknown function DUF805 Mmwyl1_0427 33 COG3152 COG3152, Predicted membrane protein Function unknown 152996610 Common - threonyl-tRNA synthetase Mmwyl1_2597 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152994403 Nonpathogen - OmpA domain protein transmembrane region-containing protein Mmwyl1_0365 6 None None None 152996270 Common - hypothetical protein Mmwyl1_2248 2 None None None 152994623 Common - phage portal protein, PBSX family Mmwyl1_0588 25 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 152997147 Common - fumarylacetoacetate (FAA) hydrolase Mmwyl1_3138 58 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152994113 Common - GntR domain protein Mmwyl1_0071 143 COG2186 FadR, Transcriptional regulators Transcription 152994680 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0646 29 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152995235 Common - sigma54 specific transcriptional regulator, Fis family Mmwyl1_1206 168 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152994817 Common - glycosyl hydrolase BNR repeat-containing protein Mmwyl1_0783 90 None None None 152996190 Common - hypothetical protein Mmwyl1_2168 25 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 152995619 Common - Monosaccharide-transporting ATPase Mmwyl1_1591 122 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152995738 Common - NADH:ubiquinone oxidoreductase, subunit B Mmwyl1_1712 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 152995026 Common - transcriptional regulator, TetR family Mmwyl1_0995 51 COG1309 AcrR, Transcriptional regulator Transcription 152995832 Common - hypothetical protein Mmwyl1_1808 14 None None None 152997946 Common - putative transcriptional regulator, GntR family Mmwyl1_3949 224 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152997984 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Mmwyl1_3988 222 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 152996532 Common - TIM-barrel protein, yjbN family Mmwyl1_2513 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 152994377 Common - membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG) Mmwyl1_0339 34 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 152997682 Common - transcriptional regulator, LysR family Mmwyl1_3681 131 COG0583 LysR, Transcriptional regulator Transcription 152995923 Common - glutaredoxin Mmwyl1_1899 25 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152996606 Common - phenylalanyl-tRNA synthetase, alpha subunit Mmwyl1_2593 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 152995529 Common - hypothetical protein Mmwyl1_1501 7 None None None 152997950 Common - glycerol kinase Mmwyl1_3953 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 152994312 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0270 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152997187 Common - 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Mmwyl1_3179 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 152994397 Common - urea amidolyase related protein Mmwyl1_0359 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 152995520 Common - sigma54 specific transcriptional regulator, Fis family Mmwyl1_1491 173 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152995824 Common - hypothetical protein Mmwyl1_1800 11 None None None 152996355 Common - ApbE family lipoprotein Mmwyl1_2333 128 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 152995104 Common - major facilitator superfamily MFS_1 Mmwyl1_1073 21 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 152996267 Common - protein of unknown function DUF84 Mmwyl1_2245 31 COG1986 COG1986, Uncharacterized conserved protein Function unknown 152994289 Common - UspA Mmwyl1_0247 8 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 152997256 Common - DsrC family protein Mmwyl1_3250 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 152994156 Common - extracellular solute-binding protein family 5 Mmwyl1_0114 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152995064 Common - thioesterase superfamily protein Mmwyl1_1033 137 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 152996487 Common - nucleoside recognition domain protein Mmwyl1_2465 23 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 152994351 Common - type II secretion system protein Mmwyl1_0310 78 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 152995241 Common - Rhs element Vgr protein Mmwyl1_1212 63 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 152995205 Common - hypothetical protein Mmwyl1_1176 5 None None None 152995780 Common - Carbonate dehydratase Mmwyl1_1754 148 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 152996873 Common - ubiquinone biosynthesis O-methyltransferase Mmwyl1_2861 169 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 152994828 Common - polysaccharide export protein Mmwyl1_0794 114 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 152995310 Common - outer membrane chaperone Skp (OmpH) Mmwyl1_1281 16 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 152996346 Common - Ectoine/hydroxyectoine ABC transporter permease protein EhuD Mmwyl1_2324 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152997689 Common - peptidylprolyl isomerase FKBP-type Mmwyl1_3688 128 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 152994517 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_0480 128 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152998380 Common - DNA-directed RNA polymerase, omega subunit Mmwyl1_4385 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 152994838 Common - polysaccharide biosynthesis protein Mmwyl1_0804 7 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 152995253 Common - hypothetical protein Mmwyl1_1224 36 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 152997996 Common - extracellular solute-binding protein family 3 Mmwyl1_4000 26 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152996947 Nonpathogen - hypothetical protein Mmwyl1_2936 11 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 152994772 Common - GTP-binding protein TypA Mmwyl1_0738 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 152996191 Common - methionine synthase Mmwyl1_2169 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 152996524 Nonpathogen - hypothetical protein Mmwyl1_2505 1 None None None 152996573 Common - Gluconate transporter Mmwyl1_2554 81 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 152996921 Common - PhoH family protein Mmwyl1_2910 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 152996659 Common - preprotein translocase, YajC subunit Mmwyl1_2646 93 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 152994799 Common - tRNA (guanine-N(7)-)-methyltransferase Mmwyl1_0765 174 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 152996648 Common - N-acetylmuramoyl-L-alanine amidase Mmwyl1_2635 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 152997389 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_3386 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152994632 Nonpathogen - hypothetical protein Mmwyl1_0598 3 None None None 152997699 Common - ABC transporter related Mmwyl1_3698 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152995800 Common - protein of unknown function DUF6 transmembrane Mmwyl1_1774 105 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 152997582 Common - protein of unknown function DUF1078 domain protein Mmwyl1_3580 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 152997302 Common - response regulator receiver protein Mmwyl1_3297 166 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152995596 Common - tRNA/rRNA methyltransferase (SpoU) Mmwyl1_1568 21 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 152997067 Common - transcriptional regulator, LysR family Mmwyl1_3057 86 COG0583 LysR, Transcriptional regulator Transcription 152995557 Common - hypothetical protein Mmwyl1_1529 45 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 152994763 Common - inner-membrane translocator Mmwyl1_0729 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 152995518 Common - Agmatine deiminase Mmwyl1_1489 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 152997043 Common - protein of unknown function DUF86 Mmwyl1_3032 51 COG2361 COG2361, Uncharacterized conserved protein Function unknown 152995133 Common - protease Do Mmwyl1_1102 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 152996331 Common - acetate kinase Mmwyl1_2309 162 COG0282 ackA, Acetate kinase Energy production and conversion 152994221 Common - protein of unknown function DUF81 Mmwyl1_0179 82 COG0730 COG0730, Predicted permeases General function prediction only 152996976 Common - Tfp pilus assembly protein FimT Mmwyl1_2965 7 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 152996684 Common - Rieske (2Fe-2S) domain protein Mmwyl1_2671 82 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 152995837 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Mmwyl1_1813 123 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 152995485 Common - aminoglycoside phosphotransferase Mmwyl1_1456 50 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 152994896 Common - aldehyde dehydrogenase Mmwyl1_0864 191 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152995111 Common - 6-phosphogluconate dehydratase Mmwyl1_1080 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 152994691 Common - TPR repeat-containing protein Mmwyl1_0657 43 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 152995671 Common - response regulator receiver modulated diguanylate cyclase Mmwyl1_1645 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152997989 Nonpathogen - hypothetical protein Mmwyl1_3993 1 None None None 152996589 Common - SMC domain protein Mmwyl1_2572 34 COG3910 COG3910, Predicted ATPase General function prediction only 152997433 Common - flagellar biosynthesis protein FlhA Mmwyl1_3430 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 152994608 Common - hypothetical protein Mmwyl1_0573 10 None None None 152995903 Common - TRAP transporter, 4TM/12TM fusion protein Mmwyl1_1879 107 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 152995616 Common - GCN5-related N-acetyltransferase Mmwyl1_1588 53 COG0456 RimI, Acetyltransferases General function prediction only 152996260 Nonpathogen - hypothetical protein Mmwyl1_2238 1 None None None 152996251 Common - protein of unknown function DUF335 SprT Mmwyl1_2229 26 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 152996542 Common - hypothetical protein Mmwyl1_2523 5 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 152994942 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0911 53 COG2962 RarD, Predicted permeases General function prediction only 152995991 Common - Alcohol dehydrogenase GroES domain protein Mmwyl1_1967 217 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 152996619 Common - arginine biosynthesis bifunctional protein ArgJ Mmwyl1_2606 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 152995284 Common - Phosphoenolpyruvate carboxylase Mmwyl1_1255 120 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 152996177 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Mmwyl1_2155 187 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 152997110 Common - phenylacetate degradation Mmwyl1_3100 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 152995359 Common - oxidoreductase molybdopterin binding Mmwyl1_1330 113 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 152996144 Nonpathogen - hypothetical protein Mmwyl1_2122 2 None None None 152997531 Common - major facilitator superfamily MFS_1 Mmwyl1_3528 65 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152997901 Common - protein of unknown function DUF886 Mmwyl1_3904 31 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 152994062 Common - RNA-binding S4 domain protein Mmwyl1_0019 99 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 152996188 Common - hypothetical protein Mmwyl1_2166 20 None None None 152996775 Common - extracellular solute-binding protein family 1 Mmwyl1_2762 73 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152995360 Common - Ferric reductase domain protein transmembrane component domain Mmwyl1_1331 76 COG2717 COG2717, Predicted membrane protein Function unknown 152998356 Common - ribonuclease PH Mmwyl1_4361 189 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 152994430 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0392 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994840 Common - Putative protein of poly-gamma-glutamate biosynthesis (capsule formation)-like protein Mmwyl1_0806 48 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 152995539 Common - ATP-binding region, ATPase-like protein Mmwyl1_1511 8 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 152995964 Common - maf protein Mmwyl1_1940 195 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 152994756 Common - transcriptional regulator, LysR family Mmwyl1_0722 177 COG0583 LysR, Transcriptional regulator Transcription 152994556 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0520 27 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152997175 Common - Endoribonuclease L-PSP Mmwyl1_3167 71 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152994850 Common - DNA polymerase, beta domain protein region Mmwyl1_0817 10 None None None 152994615 Common - prophage PSPPH06, putative tail sheath protein Mmwyl1_0580 10 None None None 152997204 Common - major facilitator superfamily MFS_1 Mmwyl1_3196 70 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996364 Common - protein of unknown function DUF81 Mmwyl1_2342 127 COG0730 COG0730, Predicted permeases General function prediction only 152994545 Common - Protocatechuate 4,5-dioxygenase Mmwyl1_0509 30 None None None 152995428 Common - addiction module toxin, RelE/StbE family Mmwyl1_1399 14 None None None 152995847 Common - Acyl-CoA dehydrogenase type 2 domain Mmwyl1_1823 74 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 152996126 Common - hypothetical protein Mmwyl1_2104 143 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 152996070 Common - amidophosphoribosyltransferase Mmwyl1_2048 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 152995159 Common - 5-formyltetrahydrofolate cyclo-ligase Mmwyl1_1129 186 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 152994437 Common - transcriptional regulator, AraC family Mmwyl1_0399 92 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995134 Common - amino-acid N-acetyltransferase Mmwyl1_1103 198 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 152998472 Common - Quinone oxidoreductase putative YhdH/YhfP Mmwyl1_4477 169 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 152994191 Common - extracellular solute-binding protein family 3 Mmwyl1_0149 130 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152997908 Common - protein of unknown function DUF112 transmembrane Mmwyl1_3911 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152994370 Common - amino acid-binding ACT domain protein Mmwyl1_0332 29 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 152997522 Common - glutamine amidotransferase class-I Mmwyl1_3519 74 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 152995912 Common - H+transporting two-sector ATPase alpha/beta subunit central region Mmwyl1_1888 200 COG1158 Rho, Transcription termination factor Transcription 152995475 Common - cobalamin synthesis protein P47K Mmwyl1_1446 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 152997100 Common - phenylacetic acid degradation protein paaN Mmwyl1_3090 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996085 Common - transport system permease protein Mmwyl1_2063 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152994968 Common - GCN5-related N-acetyltransferase Mmwyl1_0937 16 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152994755 Common - FAD dependent oxidoreductase Mmwyl1_0721 134 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152996756 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2743 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994906 Common - ABC transporter related Mmwyl1_0874 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 152997871 Common - excinuclease ATPase subunit Mmwyl1_3872 14 None None None 152995279 Common - multi-sensor hybrid histidine kinase Mmwyl1_1250 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997071 Common - Polypeptide-transport-associated domain protein ShlB-type Mmwyl1_3061 60 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 152997132 Common - catalytic domain of components of various dehydrogenase complexes Mmwyl1_3122 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 152996409 Nonpathogen - hypothetical protein Mmwyl1_2387 1 None None None 152996035 Common - KDPG and KHG aldolase Mmwyl1_2013 123 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 152996698 Common - TRAP transporter, 4TM/12TM fusion protein Mmwyl1_2685 124 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 152997482 Nonpathogen - glycosyl transferase family 9 Mmwyl1_3479 2 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 152995772 Nonpathogen - hypothetical protein Mmwyl1_1746 1 None None None 152997402 Common - conserved hypothetical selenoprotein Mmwyl1_3399 29 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 152997233 Common - Inosine kinase Mmwyl1_3227 68 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 152995888 Common - small integral membrane protein Mmwyl1_1864 20 COG5472 COG5472, Predicted small integral membrane protein Function unknown 152994924 Common - diguanylate cyclase Mmwyl1_0892 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152995413 Common - molecular chaperone Mmwyl1_1384 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 152997480 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Mmwyl1_3477 192 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152997769 Common - tRNA (guanine-N1)-methyltransferase Mmwyl1_3768 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 152997415 Nonpathogen - Heme exporter protein D (CcmD) Mmwyl1_3412 1 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 152995762 Common - ATPase associated with various cellular activities AAA_3 Mmwyl1_1736 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 152996728 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2715 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152995072 Common - RNA polymerase, sigma 70 subunit, RpoD Mmwyl1_1041 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 152997636 Common - hypothetical protein Mmwyl1_3634 4 None None None 152998131 Common - threonine dehydratase, biosynthetic Mmwyl1_4135 226 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 152997616 Common - putative cold-shock DNA-binding domain protein Mmwyl1_3614 181 COG1278 CspC, Cold shock proteins Transcription 152996113 Common - 3-isopropylmalate dehydratase, large subunit Mmwyl1_2091 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 152994083 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0040 14 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152998311 Common - fructose-bisphosphate aldolase, class II, Calvin cycle subtype Mmwyl1_4316 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 152994724 Common - ABC transporter related Mmwyl1_0690 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152997912 Common - Auxin Efflux Carrier Mmwyl1_3915 101 COG0679 COG0679, Predicted permeases General function prediction only 152995147 Common - nitrogen regulatory protein P-II Mmwyl1_1116 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 152997430 Common - response regulator receiver protein Mmwyl1_3427 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152994931 Common - translation elongation factor P Mmwyl1_0899 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 152994411 Nonpathogen - hypothetical protein Mmwyl1_0373 1 None None None 152994988 Common - UreE urease accessory domain protein Mmwyl1_0957 60 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 152995273 Common - GTP-binding protein LepA Mmwyl1_1244 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 152997731 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3730 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997967 Common - cyclase/dehydrase Mmwyl1_3970 99 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 152995859 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_1835 48 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997059 Common - beta-ketoadipyl CoA thiolase Mmwyl1_3048 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152995852 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_1828 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152995797 Common - alpha amylase catalytic region Mmwyl1_1771 136 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 152996008 Common - Monosaccharide-transporting ATPase Mmwyl1_1985 104 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152997091 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Mmwyl1_3081 235 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 152995168 Common - protein of unknown function UPF0060 Mmwyl1_1139 82 COG1742 COG1742, Uncharacterized conserved protein Function unknown 152995044 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_1013 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995954 Common - hypothetical protein Mmwyl1_1930 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 152996170 Common - hypothetical protein Mmwyl1_2148 49 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 152995016 Common - DEAD/DEAH box helicase domain protein Mmwyl1_0985 230 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152998181 Common - Auxin Efflux Carrier Mmwyl1_4185 122 COG0679 COG0679, Predicted permeases General function prediction only 152996846 Common - bacterioferritin Mmwyl1_2834 97 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 152998143 Common - GMP synthase, large subunit Mmwyl1_4147 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 152998269 Common - Ribosomal protein L25/L23 Mmwyl1_4274 217 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 152996226 Common - GCN5-related N-acetyltransferase Mmwyl1_2204 6 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152996380 Common - hypothetical protein Mmwyl1_2358 2 None None None 152994734 Common - Exonuclease RNase T and DNA polymerase III Mmwyl1_0700 36 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 152998228 Common - ribosomal protein S20 Mmwyl1_4233 203 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 152996198 Common - protein of unknown function DUF395 YeeE/YedE Mmwyl1_2176 64 COG2391 COG2391, Predicted transporter component General function prediction only 152997274 Common - Cupin 4 family protein Mmwyl1_3269 63 COG2850 COG2850, Uncharacterized conserved protein Function unknown 152998202 Common - dual specificity protein phosphatase Mmwyl1_4206 3 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 152996214 Common - Biopolymer transport TolR Mmwyl1_2192 140 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 152998447 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_4452 60 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152994146 Common - hypothetical protein Mmwyl1_0104 14 None None None 152998340 Common - extracellular solute-binding protein family 1 Mmwyl1_4345 36 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152995081 Common - ApaG domain protein Mmwyl1_1050 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 152995919 Common - Glutamate dehydrogenase (NADP(+)) Mmwyl1_1895 165 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 152997426 Common - MotA/TolQ/ExbB proton channel Mmwyl1_3423 100 COG1291 MotA, Flagellar motor component Cell motility and secretion 152997625 Common - oxaloacetate decarboxylase alpha subunit Mmwyl1_3623 211 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 152996297 Common - NADH dehydrogenase (quinone) Mmwyl1_2275 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 152997315 Common - protein of unknown function DUF419 Mmwyl1_3310 42 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 152995575 Common - ParA family protein Mmwyl1_1547 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 152995198 Common - ribose-phosphate pyrophosphokinase Mmwyl1_1169 204 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 152998451 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4456 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994687 Nonpathogen - FeoA family protein Mmwyl1_0653 3 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 152994560 Common - aldo/keto reductase Mmwyl1_0524 192 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 152997347 Common - signal transduction histidine kinase, LytS Mmwyl1_3342 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 152997980 Common - NADH dehydrogenase (quinone) Mmwyl1_3984 192 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 152998480 Common - 60 kDa inner membrane insertion protein Mmwyl1_4485 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 152995436 Common - ribonuclease R Mmwyl1_1407 206 COG0557 VacB, Exoribonuclease R Transcription 152995707 Common - transcriptional regulator, LysR family Mmwyl1_1681 171 COG0583 LysR, Transcriptional regulator Transcription 152997015 Common - protein of unknown function DUF37 Mmwyl1_3004 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 152998223 Common - peptidylprolyl isomerase FKBP-type Mmwyl1_4228 136 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 152995272 Common - riboflavin synthase, alpha subunit Mmwyl1_1243 208 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 152996456 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_2434 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152998395 Common - two component transcriptional regulator, winged helix family Mmwyl1_4400 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152997825 Common - D-serine ammonia-lyase Mmwyl1_3826 115 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 152996908 Nonpathogen - hypothetical protein Mmwyl1_2896 2 None None None 152996242 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Mmwyl1_2220 33 COG2138 COG2138, Uncharacterized conserved protein Function unknown 152996316 Common - transcriptional regulator, LysR family Mmwyl1_2294 186 COG0583 LysR, Transcriptional regulator Transcription 152994337 Common - Ig family protein Mmwyl1_0296 66 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 152994661 Common - transposase IS3/IS911 family protein Mmwyl1_0627 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152995712 Common - extracellular solute-binding protein family 5 Mmwyl1_1686 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152996374 Common - cell division topological specificity factor MinE Mmwyl1_2352 74 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 152995220 Nonpathogen - Peptidoglycan-binding LysM Mmwyl1_1191 2 None None None 152998261 Common - ribosomal protein L14 Mmwyl1_4266 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 152998019 Common - prevent-host-death family protein Mmwyl1_4023 50 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 152995333 Common - stationary-phase survival protein SurE Mmwyl1_1304 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 152995425 Common - hypothetical protein Mmwyl1_1396 6 None None None 152996003 Common - cation diffusion facilitator family transporter Mmwyl1_1980 204 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 152996463 Common - hypothetical protein Mmwyl1_2441 7 None None None 152997086 Common - haloacid dehalogenase, type II Mmwyl1_3076 41 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 152998036 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_4040 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152998307 Common - hypothetical protein Mmwyl1_4312 8 None None None 152998413 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4418 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997502 Common - YceI family protein Mmwyl1_3499 117 COG2353 COG2353, Uncharacterized conserved protein Function unknown 152994282 Common - choline/carnitine/betaine transporter Mmwyl1_0240 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 152995191 Common - aspartate/glutamate/uridylate kinase Mmwyl1_1162 160 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 152997017 Common - acetate--CoA ligase Mmwyl1_3006 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 152994659 Common - transcriptional regulator, XRE family Mmwyl1_0625 14 COG1476 COG1476, Predicted transcriptional regulators Transcription 152996898 Common - conserved helix-turn-helix protein Mmwyl1_2886 21 None None None 152998099 Common - transcriptional regulator, LysR family Mmwyl1_4103 175 COG0583 LysR, Transcriptional regulator Transcription 152997892 Common - nitroreductase Mmwyl1_3894 86 COG0778 NfnB, Nitroreductase Energy production and conversion 152996514 Common - Protein of unknown function DUF1778 Mmwyl1_2494 19 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 152998007 Common - transcriptional regulator, TraR/DksA family Mmwyl1_4011 149 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 152995467 Common - hypothetical protein Mmwyl1_1438 10 None None None 152998124 Common - 20S proteasome A and B subunits Mmwyl1_4128 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 152995186 Common - sodium:neurotransmitter symporter Mmwyl1_1157 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 152997791 Common - 2-amino-3-ketobutyrate coenzyme A ligase Mmwyl1_3792 191 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 152996097 Common - elongation factor P-like protein YeiP Mmwyl1_2075 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 152996738 Common - hypothetical protein Mmwyl1_2725 10 None None None 152996807 Common - FAD dependent oxidoreductase Mmwyl1_2794 104 COG0579 COG0579, Predicted dehydrogenase General function prediction only 152996954 Common - multiple antibiotic resistance (MarC)-related protein Mmwyl1_2943 156 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 152994594 Nonpathogen - hypothetical protein Mmwyl1_0559 1 None None None 152994172 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0130 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994198 Common - hypothetical protein Mmwyl1_0156 4 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 152996431 Common - BolA family protein Mmwyl1_2409 78 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 152997289 Common - major facilitator superfamily MFS_1 Mmwyl1_3284 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152998278 Common - DNA-directed RNA polymerase, beta subunit Mmwyl1_4283 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 152994498 Common - ornithine cyclodeaminase/mu-crystallin Mmwyl1_0461 88 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 152998107 Common - sodium/hydrogen exchanger Mmwyl1_4111 191 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 152997078 Common - Succinylglutamate desuccinylase/aspartoacylase Mmwyl1_3068 13 COG3608 COG3608, Predicted deacylase General function prediction only 152997440 Common - flagellar motor switch protein FliM Mmwyl1_3437 113 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 152997447 Common - flagellar export protein FliJ Mmwyl1_3444 34 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 152994652 Common - exodeoxyribonuclease III Xth Mmwyl1_0618 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 152996800 Common - response regulator receiver protein Mmwyl1_2787 88 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152994746 Nonpathogen - hypothetical protein Mmwyl1_0712 1 None None None 152998164 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_4168 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152994713 Common - two component transcriptional regulator, LuxR family Mmwyl1_0679 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997789 Nonpathogen - hypothetical protein Mmwyl1_3788 1 None None None 152996710 Common - Xanthine dehydrogenase accessory protein XdhC Mmwyl1_2697 98 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 152996108 Common - SirA family protein Mmwyl1_2086 48 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 152995008 Common - molybdate ABC transporter, ATPase subunit Mmwyl1_0977 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 152997383 Common - Magnesium chelatase Mmwyl1_3380 125 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 152996889 Common - flavodoxin Mmwyl1_2877 73 COG0716 FldA, Flavodoxins Energy production and conversion 152995161 Common - lysyl-tRNA synthetase Mmwyl1_1132 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 152994953 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0922 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996872 Common - DNA gyrase, A subunit Mmwyl1_2860 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 152994216 Common - sigma54 specific transcriptional regulator, Fis family Mmwyl1_0174 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 152997243 Common - hypothetical protein Mmwyl1_3237 21 None None None 152995494 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1465 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998288 Common - carboxylesterase Mmwyl1_4293 51 COG1647 COG1647, Esterase/lipase General function prediction only 152996309 Common - major facilitator superfamily MFS_1 Mmwyl1_2287 190 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994880 Common - hypothetical protein Mmwyl1_0848 7 COG5340 COG5340, Predicted transcriptional regulator Transcription 152994265 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_0223 114 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995305 Common - undecaprenyl diphosphate synthase Mmwyl1_1276 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 152996746 Common - putative periplasmic ligand-binding sensor protein Mmwyl1_2733 183 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 152995585 Common - diguanylate cyclase with PAS/PAC sensor Mmwyl1_1557 187 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152997458 Common - Carboxylesterase Mmwyl1_3455 49 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152998364 Common - 7TM domain sensor diguanylate cyclase Mmwyl1_4369 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152994866 Common - polysaccharide biosynthesis protein Mmwyl1_0834 11 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 152997326 Common - protein of unknown function UPF0153 Mmwyl1_3321 11 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 152995059 Common - ribosome-binding factor A Mmwyl1_1028 186 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 152996919 Nonpathogen - hypothetical protein Mmwyl1_2908 2 None None None 152995786 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_1760 202 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152995690 Common - drug resistance transporter, Bcr/CflA subfamily Mmwyl1_1664 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996991 Common - cytochrome c biogenesis protein transmembrane region Mmwyl1_2980 114 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 152998357 Common - domain of unknown function DUF1732 Mmwyl1_4362 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 152995173 Common - Aspartoacylase Mmwyl1_1144 12 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 152995705 Common - DEAD/DEAH box helicase domain protein Mmwyl1_1679 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152995141 Common - NAD-glutamate dehydrogenase Mmwyl1_1110 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 152996525 Common - phage late control D family protein Mmwyl1_2506 34 COG3500 COG3500, Phage protein D General function prediction only 152996741 Nonpathogen - hypothetical protein Mmwyl1_2728 1 None None None 152995054 Common - Triose-phosphate isomerase Mmwyl1_1023 222 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 152997258 Common - seryl-tRNA synthetase Mmwyl1_3252 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 152998291 Common - periplasmic glucan biosynthesis protein MdoG Mmwyl1_4296 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 152997889 Common - FAD dependent oxidoreductase Mmwyl1_3891 110 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152996516 Common - Alcohol dehydrogenase zinc-binding domain protein Mmwyl1_2497 182 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 152995342 Common - molybdenum cofactor synthesis domain Mmwyl1_1313 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 152995588 Nonpathogen - hypothetical protein Mmwyl1_1560 2 None None None 152998300 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4305 192 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 152996910 Common - 3-demethylubiquinone-9 3-methyltransferase Mmwyl1_2898 51 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 152995085 Common - Organic solvent tolerance protein Mmwyl1_1054 118 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 152994489 Common - Gamma-glutamyltransferase Mmwyl1_0452 145 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 152995160 Common - protein of unknown function DUF710 Mmwyl1_1130 58 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 152997712 Common - hypothetical protein Mmwyl1_3711 7 None None None 152997339 Nonpathogen - hypothetical protein Mmwyl1_3334 2 None None None 152996616 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Mmwyl1_2603 143 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 152997865 Nonpathogen - hypothetical protein Mmwyl1_3866 11 None None None 152995435 Common - protein of unknown function DUF299 Mmwyl1_1406 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 152994328 Common - putative transcriptional regulator, TetR family Mmwyl1_0287 9 COG1309 AcrR, Transcriptional regulator Transcription 152995443 Nonpathogen - hypothetical protein Mmwyl1_1414 1 None None None 152994818 Common - TPR repeat-containing protein Mmwyl1_0784 16 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 152995249 Common - hypothetical protein Mmwyl1_1220 4 None None None 152994574 Common - 2OG-Fe(II) oxygenase Mmwyl1_0538 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 152995688 Common - tryptophan synthase, beta subunit Mmwyl1_1662 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 152997788 Common - hypothetical protein Mmwyl1_3787 4 None None None 152997953 Common - protein of unknown function DUF81 Mmwyl1_3956 102 COG0730 COG0730, Predicted permeases General function prediction only 152994686 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Mmwyl1_0652 90 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 152994078 Common - transcriptional regulator, LysR family Mmwyl1_0035 166 COG0583 LysR, Transcriptional regulator Transcription 152998113 Common - Shikimate kinase Mmwyl1_4117 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 152995834 Common - permease Mmwyl1_1810 103 COG0701 COG0701, Predicted permeases General function prediction only 152994104 Common - shikimate 5-dehydrogenase Mmwyl1_0062 221 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 152996168 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Mmwyl1_2146 217 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 152995394 Common - Thiopurine S-methyltransferase Mmwyl1_1365 32 None None None 152997263 Nonpathogen - hypothetical protein Mmwyl1_3257 1 None None None 152996869 Common - Prephenate dehydrogenase., 3-phosphoshikimate 1-carboxyvinyltransferase Mmwyl1_2857 180 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 152997743 Common - Thymidylate synthase Mmwyl1_3742 135 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 152995123 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1092 161 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152994638 Common - extracellular solute-binding protein family 1 Mmwyl1_0604 91 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152994252 Common - hypothetical protein Mmwyl1_0210 18 COG0645 COG0645, Predicted kinase General function prediction only 152997904 Nonpathogen - hypothetical protein Mmwyl1_3907 2 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 152997473 Common - ABC transporter related Mmwyl1_3470 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 152994260 Common - putative malonate transporter, MadM subunit Mmwyl1_0218 9 None None None 152996158 Common - ABC transporter related Mmwyl1_2136 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 152997114 Common - ABC transporter related Mmwyl1_3104 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152995727 Common - Lytic transglycosylase catalytic Mmwyl1_1701 122 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 152996501 Common - protein of unknown function DUF1185 Mmwyl1_2480 23 None None None 152996046 Common - 2-isopropylmalate synthase Mmwyl1_2024 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 152998281 Common - ribosomal protein L1 Mmwyl1_4286 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 152994522 Common - protein of unknown function DUF606 Mmwyl1_0485 42 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 152997199 Common - transcriptional regulator, MarR family Mmwyl1_3191 58 COG1846 MarR, Transcriptional regulators Transcription 152997371 Nonpathogen - hypothetical protein Mmwyl1_3368 1 None None None 152998194 Common - hypothetical protein Mmwyl1_4198 4 None None None 152995572 Common - electron transport complex, RnfABCDGE type, B subunit Mmwyl1_1544 127 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 152995877 Common - sulphate transporter Mmwyl1_1853 170 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 152995759 Common - von Willebrand factor type A Mmwyl1_1733 82 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 152996581 Common - membrane protein involved in aromatic hydrocarbon degradation Mmwyl1_2562 77 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 152996577 Common - protein of unknown function DUF1111 Mmwyl1_2558 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 152995701 Common - hypothetical protein Mmwyl1_1675 3 None None None 152998434 Common - dihydrodipicolinate synthetase Mmwyl1_4439 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 152996337 Common - peptidase A24A domain protein Mmwyl1_2315 115 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 152994887 Common - TonB-dependent hemoglobin/transferrin/lactoferrin family receptor Mmwyl1_0855 123 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 152995749 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Mmwyl1_1723 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 152995380 Common - aminotransferase class V Mmwyl1_1351 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 152997977 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3981 42 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998103 Common - protein of unknown function DUF1238 Mmwyl1_4107 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 152998215 Common - phage integrase family protein Mmwyl1_4220 5 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152997765 Common - threonine synthase Mmwyl1_3764 130 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 152995167 Common - GCN5-related N-acetyltransferase Mmwyl1_1138 17 COG0456 RimI, Acetyltransferases General function prediction only 152995242 Common - hypothetical protein Mmwyl1_1213 4 None None None 152994644 Common - HAD-superfamily hydrolase, subfamily IIB Mmwyl1_0610 26 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 152997802 Common - Dihydroxy-acid dehydratase Mmwyl1_3803 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 152995454 Common - Dopa 45-dioxygenase Mmwyl1_1425 17 COG3805 DodA, Aromatic ring-cleaving dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 152996838 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_2826 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152996717 Common - CMP/dCMP deaminase zinc-binding Mmwyl1_2704 170 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 152995227 Common - GPW/gp25 family protein Mmwyl1_1198 12 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 152997587 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mmwyl1_3585 108 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 152997728 Common - protein kinase Mmwyl1_3727 155 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 152996998 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Mmwyl1_2987 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 152994413 Common - extracellular solute-binding protein family 1 Mmwyl1_0375 43 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996664 Common - amino acid carrier protein Mmwyl1_2651 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 152997937 Common - amidohydrolase 2 Mmwyl1_3940 45 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 152996333 Nonpathogen - hypothetical protein Mmwyl1_2311 1 None None None 152996981 Common - transcriptional regulator, LysR family Mmwyl1_2970 171 COG0583 LysR, Transcriptional regulator Transcription 152997844 Common - transcriptional regulator, LysR family Mmwyl1_3845 188 COG0583 LysR, Transcriptional regulator Transcription 152995626 Common - Myo-inositol catabolism IolB domain protein Mmwyl1_1598 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 152998136 Common - sugar fermentation stimulation protein Mmwyl1_4140 108 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 152997089 Common - GCN5-related N-acetyltransferase Mmwyl1_3079 35 COG2153 ElaA, Predicted acyltransferase General function prediction only 152995939 Common - sulfatase Mmwyl1_1915 64 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 152995484 Common - ATP-dependent DNA helicase, RecQ family Mmwyl1_1455 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 152997332 Common - amidohydrolase 2 Mmwyl1_3327 5 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 152996034 Common - 2-dehydro-3-deoxygalactonokinase Mmwyl1_2012 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 152996219 Common - quinolinate synthetase complex, A subunit Mmwyl1_2197 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 152997211 Common - sigma54 specific transcriptional regulator, Fis family Mmwyl1_3203 169 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 152995799 Common - mannosyl-3-phosphoglycerate phosphatase family Mmwyl1_1773 36 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 152998043 Common - thiamine-monophosphate kinase Mmwyl1_4047 212 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 152994837 Nonpathogen - hypothetical protein Mmwyl1_0803 1 None None None 152994505 Common - TonB-dependent receptor Mmwyl1_0468 72 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 152994110 Common - globin Mmwyl1_0068 51 COG2346 COG2346, Truncated hemoglobins General function prediction only 152994494 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0457 75 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995110 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Mmwyl1_1079 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 152997143 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3134 41 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994482 Common - acetylornithine deacetylase (ArgE) Mmwyl1_0445 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152994588 Common - RNA methyltransferase, TrmH family, group 2 Mmwyl1_0552 158 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 152996427 Nonpathogen - hypothetical protein Mmwyl1_2405 1 None None None 152997596 Common - HemY domain protein Mmwyl1_3594 52 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 152997301 Common - anti-sigma-factor antagonist Mmwyl1_3296 18 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 152997907 Nonpathogen - hypothetical protein Mmwyl1_3910 3 None None None 152996287 Common - hydrolase, TatD family Mmwyl1_2265 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 152995119 Common - xylulokinase Mmwyl1_1088 182 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 152995071 Common - PhoH family protein Mmwyl1_1040 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 152995600 Common - Sterol-binding domain protein Mmwyl1_1572 16 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 152996392 Common - heat shock protein Hsp90 Mmwyl1_2370 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 152996408 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Mmwyl1_2386 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 152994826 Nonpathogen - hypothetical protein Mmwyl1_0792 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 152997838 Common - 5'-Nucleotidase domain protein Mmwyl1_3839 110 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 152998238 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Mmwyl1_4243 196 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 152995370 Common - hypothetical protein Mmwyl1_1341 40 COG4325 COG4325, Predicted membrane protein Function unknown 152997820 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_3821 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994082 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_0039 103 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996205 Common - sulfate adenylyltransferase, large subunit Mmwyl1_2183 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 152997559 Common - phospholipid/glycerol acyltransferase Mmwyl1_3557 29 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 152998298 Common - conserved hypothetical protein; putative peptide signal Mmwyl1_4303 13 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 152994122 Common - transcriptional regulator, LysR family Mmwyl1_0080 173 COG0583 LysR, Transcriptional regulator Transcription 152997176 Common - ornithine cyclodeaminase/mu-crystallin Mmwyl1_3168 82 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 152994301 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0259 41 None None None 152996635 Common - S-adenosyl-methyltransferase MraW Mmwyl1_2622 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 152997929 Nonpathogen - hypothetical protein Mmwyl1_3932 1 None None None 152997045 Common - hypothetical protein Mmwyl1_3034 3 None None None 152995971 Common - AraC-type transcriptional regulator domain protein Mmwyl1_1947 122 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994364 Common - alpha amylase catalytic region Mmwyl1_0324 157 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 152998275 Common - ribosomal protein S7 Mmwyl1_4280 241 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 152994537 Common - N-acetyltransferase Mmwyl1_0501 44 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 152996369 Common - hypothetical protein Mmwyl1_2347 24 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 152994055 Common - ybaK/ebsC protein Mmwyl1_0012 118 COG2606 EbsC, Uncharacterized conserved protein Function unknown 152996923 Common - CBS domain containing protein Mmwyl1_2912 216 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 152995003 Common - transcriptional regulator, GntR family Mmwyl1_0972 122 COG2188 PhnF, Transcriptional regulators Transcription 152997571 Common - flagellar protein FlaG protein Mmwyl1_3569 12 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 152998257 Common - ribosomal protein S8 Mmwyl1_4262 220 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 152996015 Common - sodium/hydrogen exchanger Mmwyl1_1993 144 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 152997028 Common - AMP-dependent synthetase and ligase Mmwyl1_3017 199 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152997504 Nonpathogen - hypothetical protein Mmwyl1_3501 1 None None None 152996799 Common - PAS/PAC sensor signal transduction histidine kinase Mmwyl1_2786 223 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 152994408 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_0370 22 None None None 152994383 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0345 110 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152998032 Common - DJ-1 family protein Mmwyl1_4036 99 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 152994207 Common - RimK domain protein ATP-grasp Mmwyl1_0165 65 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 152994235 Common - transcriptional regulator, TetR family Mmwyl1_0193 66 COG1309 AcrR, Transcriptional regulator Transcription 152996986 Common - MATE efflux family protein Mmwyl1_2975 126 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 152995405 Common - cobalamin biosynthesis protein CobW Mmwyl1_1376 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 152997392 Common - ornithine carbamoyltransferase Mmwyl1_3389 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 152997867 Common - oxidoreductase FAD/NAD(P)-binding domain protein Mmwyl1_3868 118 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 152995975 Common - Fructose-bisphosphate aldolase Mmwyl1_1951 40 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 152997775 Common - NUDIX hydrolase Mmwyl1_3774 81 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 152994119 Common - FAD linked oxidase-like protein Mmwyl1_0077 34 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 152998049 Common - ABC transporter related Mmwyl1_4053 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 152997511 Common - oxidoreductase domain protein Mmwyl1_3508 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152994258 Common - Glutathionylspermidine amidase Mmwyl1_0216 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 152996470 Common - peptidase M15D vanX D-ala-D-ala dipeptidase Mmwyl1_2448 48 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 152998195 Common - AAA ATPase central domain protein Mmwyl1_4199 138 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 152997035 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_3024 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152995981 Nonpathogen - hypothetical protein Mmwyl1_1957 12 None None None 152994436 Common - Radical SAM domain protein Mmwyl1_0398 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 152995963 Common - Rod shape-determining protein MreD Mmwyl1_1939 63 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 152997290 Common - hypothetical protein Mmwyl1_3285 4 None None None 152998154 Common - cytochrome d ubiquinol oxidase, subunit II Mmwyl1_4158 151 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 152994656 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Mmwyl1_0622 175 COG0756 Dut, dUTPase Nucleotide transport and metabolism 152994555 Common - 2-dehydro-3-deoxyglucarate aldolase Mmwyl1_0519 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 152995689 Common - transcriptional regulator, TetR family Mmwyl1_1663 35 COG1309 AcrR, Transcriptional regulator Transcription 152996760 Common - hypothetical protein Mmwyl1_2747 9 None None None 152995515 Common - sodium/hydrogen exchanger Mmwyl1_1486 192 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 152998072 Common - anti-ECFsigma factor, ChrR Mmwyl1_4076 31 COG3806 ChrR, Transcriptional activator Transcription 152997021 Common - TRAP transporter, 4TM/12TM fusion protein Mmwyl1_3010 69 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 152994219 Common - protein of unknown function DUF547 Mmwyl1_0177 25 None None None 152998079 Common - hypothetical protein Mmwyl1_4083 17 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 152994711 Common - sulfatase Mmwyl1_0677 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 152994809 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0775 165 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152997189 Common - protein of unknown function DUF336 Mmwyl1_3181 21 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 152998325 Common - putative methyltransferase Mmwyl1_4330 207 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 152998418 Common - hypothetical protein Mmwyl1_4423 10 None None None 152997082 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3072 201 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152996943 Common - Mammalian cell entry related domain protein Mmwyl1_2932 63 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 152995986 Common - H+transporting two-sector ATPase gamma subunit Mmwyl1_1962 207 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 152997169 Common - FAD linked oxidase domain protein Mmwyl1_3161 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 152996056 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding Mmwyl1_2034 59 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 152994595 Nonpathogen - hypothetical protein Mmwyl1_0560 1 None None None 152994347 Common - type II and III secretion system protein Mmwyl1_0306 135 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 152998171 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_4175 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152997854 Common - putative tricarboxylic transport membrane protein Mmwyl1_3855 7 None None None 152995904 Common - TRAP transporter solute receptor, TAXI family Mmwyl1_1880 73 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 152995509 Common - FAD dependent oxidoreductase Mmwyl1_1480 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 152994306 Common - ABC transporter related Mmwyl1_0264 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 152995790 Common - TRAP transporter solute receptor, TAXI family Mmwyl1_1764 90 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 152994097 Nonpathogen - hypothetical protein Mmwyl1_0055 1 None None None 152994444 Common - phage shock protein A, PspA Mmwyl1_0406 87 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 152995864 Common - ornithine cyclodeaminase/mu-crystallin Mmwyl1_1840 85 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 152996625 Common - D-alanine--D-alanine ligase Mmwyl1_2612 220 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 152998301 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4306 183 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 152995098 Common - Flagellar basal body P-ring biosynthesis protein-like protein Mmwyl1_1067 35 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 152996201 Common - protein of unknown function DUF1332 Mmwyl1_2179 24 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 152994459 Common - transcriptional regulator, MarR family Mmwyl1_0421 113 COG1846 MarR, Transcriptional regulators Transcription 152994872 Common - dTDP-4-dehydrorhamnose reductase Mmwyl1_0840 167 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 152994762 Common - inner-membrane translocator Mmwyl1_0728 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 152995763 Common - hypothetical protein Mmwyl1_1737 5 None None None 152997465 Common - ribosomal protein L9 Mmwyl1_3462 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 152994246 Common - Ornithine cyclodeaminase Mmwyl1_0204 89 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 152996862 Common - iojap-like protein Mmwyl1_2850 147 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 152996028 Common - transcriptional regulator, LysR family Mmwyl1_2006 164 COG0583 LysR, Transcriptional regulator Transcription 152997516 Common - transcriptional regulator, TetR family Mmwyl1_3513 61 COG1309 AcrR, Transcriptional regulator Transcription 152995379 Common - Fe-S metabolism associated SufE Mmwyl1_1350 87 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 152995180 Common - transcriptional regulator, TrmB Mmwyl1_1151 82 COG1846 MarR, Transcriptional regulators Transcription 152998254 Common - ribosomal protein S5 Mmwyl1_4259 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 152996349 Common - histidine kinase Mmwyl1_2327 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996937 Common - hypothetical protein Mmwyl1_2926 112 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 152995414 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1385 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996538 Common - ATP-dependent helicase HrpA Mmwyl1_2519 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 152998182 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_4186 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996867 Common - ribosomal protein S1 Mmwyl1_2855 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 152997935 Common - Protocatechuate 4,5-dioxygenase Mmwyl1_3938 31 COG3384 COG3384, Uncharacterized conserved protein Function unknown 152996563 Nonpathogen - hypothetical protein Mmwyl1_2544 2 None None None 152997360 Common - protein of unknown function DUF1568 Mmwyl1_3356 17 None None None 152996114 Common - 3-isopropylmalate dehydratase, small subunit Mmwyl1_2092 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 152997279 Common - UspA domain protein Mmwyl1_3274 99 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 152997945 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3948 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997235 Common - import inner membrane translocase subunit Tim44 Mmwyl1_3229 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 152995474 Nonpathogen - hypothetical protein Mmwyl1_1445 6 None None None 152996412 Common - thiamine biosynthesis protein ThiS Mmwyl1_2390 19 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 152995530 Common - YHS domain protein Mmwyl1_1502 19 COG3350 COG3350, Uncharacterized conserved protein Function unknown 152997692 Common - YebG family protein Mmwyl1_3691 17 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 152996832 Common - nitrate transporter Mmwyl1_2820 89 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 152996432 Common - toluene tolerance family protein Mmwyl1_2410 28 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 152996426 Common - 2-alkenal reductase Mmwyl1_2404 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 152997353 Common - iron-containing alcohol dehydrogenase Mmwyl1_3348 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 152995653 Common - periplasmic binding protein Mmwyl1_1626 81 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 152996826 Common - nitrite reductase (NAD(P)H), small subunit Mmwyl1_2814 44 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 152996266 Common - Chorismate synthase Mmwyl1_2244 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 152995219 Nonpathogen - hypothetical protein Mmwyl1_1190 1 None None None 152994168 Common - hypothetical protein Mmwyl1_0126 17 None None None 152994994 Common - transcriptional regulator, LysR family Mmwyl1_0963 192 COG0583 LysR, Transcriptional regulator Transcription 152997002 Common - histidine triad (HIT) protein Mmwyl1_2991 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 152997568 Nonpathogen - hypothetical protein Mmwyl1_3566 1 None None None 152996466 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_2444 114 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152996571 Common - Hydroxypyruvate isomerase Mmwyl1_2552 79 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 152995297 Common - tetrahydrodipicolinate succinylase, putative Mmwyl1_1268 35 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 152994745 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0711 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152998187 Common - two component transcriptional regulator, winged helix family Mmwyl1_4191 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152998316 Common - protein of unknown function DUF558 Mmwyl1_4321 198 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 152996957 Common - NIPSNAP family containing protein Mmwyl1_2946 18 None None None 152996706 Nonpathogen - CRISPR-associated RAMP protein, Cmr1 family Mmwyl1_2693 6 COG1367 COG1367, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 152994134 Common - Cytochrome o ubiquinol oxidase subunit IV Mmwyl1_0092 59 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 152995393 Common - Radical SAM domain protein Mmwyl1_1364 75 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 152997217 Common - ABC transporter related Mmwyl1_3209 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152998064 Common - hypothetical protein Mmwyl1_4068 5 None None None 152996699 Common - CRISPR-associated protein, Csy4 family Mmwyl1_2686 18 None None None 152997940 Common - amidohydrolase 2 Mmwyl1_3943 41 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 152996235 Common - putative CheW protein Mmwyl1_2213 172 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 152994170 Common - methylated-DNA--protein-cysteine methyltransferase Mmwyl1_0128 206 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 152996507 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2486 158 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 152996729 Common - extracellular solute-binding protein family 1 Mmwyl1_2716 70 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152997655 Common - hypothetical protein Mmwyl1_3654 10 None None None 152997299 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_3294 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 152998063 Common - lipoprotein, putative Mmwyl1_4067 35 None None None 152998374 Common - major facilitator superfamily MFS_1 Mmwyl1_4379 74 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 152994733 Common - putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase Mmwyl1_0699 186 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 152995543 Common - hypothetical protein Mmwyl1_1515 19 None None None 152995739 Common - NADH:ubiquinone oxidoreductase, subunit C Mmwyl1_1713 46 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 152995343 Common - molybdenum cofactor biosynthesis protein B Mmwyl1_1314 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 152998264 Common - ribosomal protein L16 Mmwyl1_4269 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 152996245 Common - hypothetical protein Mmwyl1_2223 19 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 152997647 Common - hypothetical protein Mmwyl1_3645 2 None None None 152997922 Common - oxaloacetate decarboxylase alpha subunit Mmwyl1_3925 203 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 152995023 Common - Pyrrolo-quinoline quinone Mmwyl1_0992 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 152995382 Common - radical SAM enzyme, Cfr family Mmwyl1_1353 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 152996362 Common - flavodoxin/nitric oxide synthase Mmwyl1_2340 116 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 152994678 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0644 69 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152994065 Common - ABC transporter related Mmwyl1_0022 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152996084 Common - transport system permease protein Mmwyl1_2062 185 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 152995809 Common - putative adenylyl cyclase CyaB Mmwyl1_1784 17 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 152995943 Common - PepSY-associated TM helix domain protein Mmwyl1_1919 58 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 152994640 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0606 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152995456 Common - peptidylprolyl isomerase FKBP-type Mmwyl1_1427 128 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 152997700 Common - multicopper oxidase type 3 Mmwyl1_3699 132 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 152997794 Common - Glutaminase Mmwyl1_3795 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 152995565 Nonpathogen - hypothetical protein Mmwyl1_1537 1 None None None 152997711 Common - signal peptidase I Mmwyl1_3710 184 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 152998157 Common - ABC-type Fe3+ transport system, periplasmic component Mmwyl1_4161 30 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152998148 Common - peptidase M20 Mmwyl1_4152 93 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152996652 Common - ribosome small subunit-dependent GTPase A Mmwyl1_2639 163 COG1162 COG1162, Predicted GTPases General function prediction only 152997663 Common - methylmalonate-semialdehyde dehydrogenase Mmwyl1_3662 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152998097 Common - amidohydrolase Mmwyl1_4101 171 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 152995189 Common - Ectoine synthase Mmwyl1_1160 35 None None None 152996459 Common - Succinylglutamate desuccinylase/aspartoacylase Mmwyl1_2437 24 COG3608 COG3608, Predicted deacylase General function prediction only 152998392 Common - putative signal transduction protein Mmwyl1_4397 53 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 152997308 Common - CheD Mmwyl1_3303 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 152995697 Common - AcrA-like protein Mmwyl1_1671 77 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152995807 Common - prevent-host-death family protein Mmwyl1_1782 19 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 152994167 Common - hypothetical protein Mmwyl1_0125 7 None None None 152995839 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_1815 107 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152998397 Common - response regulator receiver protein Mmwyl1_4402 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152997429 Common - chemotaxis phosphatase, CheZ Mmwyl1_3426 43 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994739 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_0705 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152994976 Common - hypothetical protein Mmwyl1_0945 11 None None None 152997733 Common - recA protein Mmwyl1_3732 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 152997943 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_3946 135 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152995275 Common - Ribonuclease III Mmwyl1_1246 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 152994893 Common - Dihydroxy-acid dehydratase Mmwyl1_0861 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 152995952 Common - diguanylate cyclase Mmwyl1_1928 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152994495 Common - amino acid permease-associated region Mmwyl1_0458 155 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 152994663 Common - ribosomal protein L28 Mmwyl1_0629 162 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 152996779 Nonpathogen - hypothetical protein Mmwyl1_2766 2 COG2105 COG2105, Uncharacterized conserved protein Function unknown 152997690 Nonpathogen - hypothetical protein Mmwyl1_3689 1 None None None 152996844 Common - DSBA oxidoreductase Mmwyl1_2832 83 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 152996735 Common - Electron transfer flavoprotein alpha subunit Mmwyl1_2722 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 152996183 Common - FAD linked oxidase domain protein Mmwyl1_2161 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 152996906 Nonpathogen - hypothetical protein Mmwyl1_2894 1 None None None 152995196 Common - transcriptional regulator, TraR/DksA family Mmwyl1_1167 23 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 152997894 Common - protein of unknown function DUF924 Mmwyl1_3897 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 152997896 Common - N-formylglutamate amidohydrolase Mmwyl1_3899 56 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 152996435 Common - ABC transporter related Mmwyl1_2413 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 152996544 Common - NAD(P)H dehydrogenase (quinone) Mmwyl1_2525 59 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 152995362 Common - hypothetical protein Mmwyl1_1333 21 None None None 152995331 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Mmwyl1_1302 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 152994921 Common - oxidoreductase domain protein Mmwyl1_0889 165 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152994275 Common - regulatory protein LacI Mmwyl1_0233 126 COG1609 PurR, Transcriptional regulators Transcription 152995646 Common - major facilitator superfamily MFS_1 Mmwyl1_1618 102 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152998414 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_4419 214 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152994475 Common - class II aldolase/adducin family protein Mmwyl1_0438 57 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 152997313 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Mmwyl1_3308 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152994050 Common - hypothetical protein Mmwyl1_0007 6 None None None 152994852 Nonpathogen - Il-IS_3, transposase Mmwyl1_0819 2 None None None 152997065 Common - 3-oxoacid CoA-transferase, A subunit Mmwyl1_3055 102 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 152998126 Common - protein of unknown function DUF971 Mmwyl1_4130 48 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 152995854 Common - flavin reductase domain protein FMN-binding Mmwyl1_1830 107 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 152998109 Common - glutamate synthase, small subunit Mmwyl1_4113 197 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 152997832 Common - alanine dehydrogenase/PNT domain protein Mmwyl1_3833 111 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 152995412 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1383 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996313 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_2291 128 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152998266 Common - ribosomal protein L22 Mmwyl1_4271 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 152998481 Common - ribonuclease P protein component Mmwyl1_4486 63 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 152994433 Common - major facilitator superfamily MFS_1 Mmwyl1_0395 83 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152997179 Common - tripartite ATP-independent periplasmic (TRAP) C4-dicarboxylate transporter subunit DctQ Mmwyl1_3171 7 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152997341 Nonpathogen - hypothetical protein Mmwyl1_3336 2 None None None 152996958 Common - GCN5-related N-acetyltransferase Mmwyl1_2947 10 None None None 152998389 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_4394 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152998169 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_4173 76 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152994804 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mmwyl1_0770 49 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 152996036 Common - SMP-30/Gluconolaconase/LRE domain protein Mmwyl1_2014 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 152995560 Common - OmpA/MotB domain protein Mmwyl1_1532 124 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 152997404 Common - protein of unknown function DUF752 Mmwyl1_3401 81 COG4121 COG4121, Uncharacterized conserved protein Function unknown 152996851 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mmwyl1_2839 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 152997417 Common - cytochrome c-type biogenesis protein CcmB Mmwyl1_3414 86 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 152996082 Common - ABC transporter related Mmwyl1_2060 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 152997223 Common - excinuclease ABC, B subunit Mmwyl1_3217 232 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 152994951 Common - protein of unknown function DUF699 ATPase putative Mmwyl1_0920 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 152997873 Common - phospholipid/glycerol acyltransferase Mmwyl1_3874 58 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 152997152 Common - BNR domain protein Mmwyl1_3143 29 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 152995914 Common - protein of unknown function DUF583 Mmwyl1_1890 76 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 152994314 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0272 95 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152998346 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4351 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152998424 Common - delta-1-pyrroline-5-carboxylate dehydrogenase Mmwyl1_4429 53 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 152994936 Common - 6-aminohexanoate-dimer hydrolase Mmwyl1_0905 104 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 152995898 Common - Monosaccharide-transporting ATPase Mmwyl1_1874 175 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152997608 Common - Aminoacyl-tRNA hydrolase Mmwyl1_3606 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 152997962 Common - GrpE protein Mmwyl1_3965 229 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 152994193 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_0151 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152994457 Common - two component transcriptional regulator, winged helix family Mmwyl1_0419 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152996051 Common - DEAD/DEAH box helicase domain protein Mmwyl1_2029 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152994879 Common - protein of unknown function DUF340 membrane Mmwyl1_0847 49 COG2431 COG2431, Predicted membrane protein Function unknown 152998120 Common - nuclease (SNase domain protein) Mmwyl1_4124 43 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 152994180 Common - major facilitator superfamily MFS_1 Mmwyl1_0138 160 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996225 Common - translation initiation factor SUI1 Mmwyl1_2203 69 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 152995778 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_1752 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152997130 Common - Ribulose-bisphosphate carboxylase Mmwyl1_3120 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 152996795 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_2782 124 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152996597 Common - transposase, IS4 Mmwyl1_2583 14 COG5433 COG5433, Transposase DNA replication, recombination, and repair 152994666 Common - basic membrane lipoprotein Mmwyl1_0632 106 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 152995882 Common - Monosaccharide-transporting ATPase Mmwyl1_1858 124 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152997617 Common - Rh family protein/ammonium transporter Mmwyl1_3615 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 152994500 Common - periplasmic binding protein Mmwyl1_0463 63 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 152997238 Common - exodeoxyribonuclease V, beta subunit Mmwyl1_3232 204 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 152996224 Common - diguanylate cyclase Mmwyl1_2202 147 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996754 Common - metal-dependent protein hydrolase Mmwyl1_2741 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 152996951 Common - hypothetical protein Mmwyl1_2940 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 152994907 Common - secretion protein HlyD family protein Mmwyl1_0875 140 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 152995060 Common - tRNA pseudouridine synthase B Mmwyl1_1029 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 152994966 Common - transcriptional regulator, LysR family Mmwyl1_0935 157 COG0583 LysR, Transcriptional regulator Transcription 152995203 Common - major facilitator superfamily MFS_1 Mmwyl1_1174 43 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 152996424 Nonpathogen - hypothetical protein Mmwyl1_2402 1 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 152994750 Common - glutaredoxin 3 Mmwyl1_0716 128 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 152995233 Common - hypothetical protein Mmwyl1_1204 43 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 152996970 Common - phage integrase family protein Mmwyl1_2959 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152994336 Common - hypothetical protein Mmwyl1_0295 7 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 152995537 Common - ABC transporter related Mmwyl1_1509 229 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 152996744 Common - diguanylate cyclase Mmwyl1_2731 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994857 Common - DegT/DnrJ/EryC1/StrS aminotransferase Mmwyl1_0824 211 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 152996041 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2019 211 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152997852 Common - isoleucyl-tRNA synthetase Mmwyl1_3853 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152995042 Common - peptide chain release factor 3 Mmwyl1_1011 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 152997485 Common - sulfatase Mmwyl1_3482 52 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 152998445 Common - aminotransferase class V Mmwyl1_4450 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 152994441 Common - periplasmic binding protein Mmwyl1_0403 101 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 152995710 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1684 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152996805 Nonpathogen - hypothetical protein Mmwyl1_2792 2 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152996824 Common - glycosyl transferase family 3 Mmwyl1_2812 108 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 152995255 Common - citrate/H+ symporter, CitMHS family Mmwyl1_1226 32 COG2851 CitM, H+/citrate symporter Energy production and conversion 152996258 Common - SirA family protein Mmwyl1_2236 80 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 152997272 Common - isocitrate dehydrogenase, NADP-dependent Mmwyl1_3267 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 152994470 Common - GCN5-related N-acetyltransferase Mmwyl1_0432 51 COG0456 RimI, Acetyltransferases General function prediction only 152998102 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_4106 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152994716 Common - Stress responsive alpha-beta barrel domain protein Mmwyl1_0682 14 None None None 152995145 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_1114 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 152994217 Common - major facilitator superfamily MFS_1 Mmwyl1_0175 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994189 Common - DNA-3-methyladenine glycosylase I Mmwyl1_0147 131 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 152995633 Nonpathogen - conserved hypothetical ABC transporter periplasmic solute-binding protein Mmwyl1_1605 6 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152994967 Common - Zn-dependent hydrolase of the beta-lactamase fold Mmwyl1_0936 82 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 152997093 Common - protein of unknown function DUF861 cupin_3 Mmwyl1_3083 17 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 152995318 Common - tRNA(Ile)-lysidine synthetase Mmwyl1_1289 180 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 152994287 Common - cytidyltransferase-related domain Mmwyl1_0245 54 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 152995761 Common - protein of unknown function DUF58 Mmwyl1_1735 80 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 152997827 Common - hypothetical protein Mmwyl1_3828 13 None None None 152996203 Common - hypothetical protein Mmwyl1_2181 12 None None None 152994770 Common - glutamine synthetase, type I Mmwyl1_0736 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 152997055 Common - transcriptional regulator, LysR family Mmwyl1_3044 193 COG0583 LysR, Transcriptional regulator Transcription 152994868 Common - hypothetical protein Mmwyl1_0836 28 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152994705 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0671 99 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152996886 Common - multi-sensor signal transduction histidine kinase Mmwyl1_2874 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 152998127 Common - protein of unknown function DUF1243 Mmwyl1_4131 15 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 152995578 Common - transposase IS3/IS911 family protein Mmwyl1_1550 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152995755 Common - Integrase catalytic region Mmwyl1_1729 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997155 Common - protein of unknown function DUF1329 Mmwyl1_3146 18 None None None 152994507 Common - Asp/Glu racemase Mmwyl1_0470 46 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 152998453 Common - hypothetical protein Mmwyl1_4458 8 None None None 152997613 Common - pseudouridine synthase, RluA family Mmwyl1_3611 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 152997745 Common - putative transcriptional regulator Mmwyl1_3744 34 COG3636 COG3636, Predicted transcriptional regulator Transcription 152996048 Common - GTP cyclohydrolase II Mmwyl1_2026 182 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 152994949 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0918 32 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152994845 Common - NAD-dependent epimerase/dehydratase Mmwyl1_0811 215 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152997280 Common - DNA topoisomerase III Mmwyl1_3275 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 152994593 Common - response regulator receiver protein Mmwyl1_0558 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997375 Common - Sel1 domain protein repeat-containing protein Mmwyl1_3372 121 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 152996575 Nonpathogen - hypothetical protein Mmwyl1_2556 1 None None None 152998402 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_4407 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 152996448 Nonpathogen - hypothetical protein Mmwyl1_2426 1 None None None 152994586 Common - sodium/hydrogen exchanger Mmwyl1_0550 149 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 152997575 Common - flagellar hook-associated protein 3 Mmwyl1_3573 88 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 152995083 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Mmwyl1_1052 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 152995244 Nonpathogen - hypothetical protein Mmwyl1_1215 1 None None None 152995032 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Mmwyl1_1001 82 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 152996473 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_2451 99 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152994779 Common - 2-polyprenylphenol 6-hydroxylase Mmwyl1_0745 183 COG0661 AarF, Predicted unusual protein kinase General function prediction only 152996784 Common - ApbE family lipoprotein Mmwyl1_2771 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 152996157 Common - hypothetical protein Mmwyl1_2135 3 None None None 152998331 Common - choline/carnitine/betaine transporter Mmwyl1_4336 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 152997812 Common - Glutathione S-transferase domain Mmwyl1_3813 62 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152996147 Common - hypothetical protein Mmwyl1_2125 5 None None None 152994847 Common - polysaccharide biosynthesis protein CapD Mmwyl1_0813 144 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152996244 Nonpathogen - hypothetical protein Mmwyl1_2222 8 None None None 152995132 Common - positive regulator of sigma E, RseC/MucC Mmwyl1_1101 40 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 152997201 Common - succinic semialdehyde dehydrogenase Mmwyl1_3193 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994547 Common - aromatic-ring-hydroxylating dioxygenase beta subunit Mmwyl1_0511 6 None None None 152995783 Common - ROK family protein Mmwyl1_1757 113 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 152996678 Common - Oxidoreductase FAD-binding domain protein Mmwyl1_2665 152 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 152995925 Common - protein of unknown function DUF984 Mmwyl1_1901 36 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 152998138 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_4142 94 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152996815 Common - Succinate dehydrogenase hydrophobic membrane anchor Mmwyl1_2803 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 152996916 Common - histone deacetylase superfamily Mmwyl1_2905 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 152994766 Common - SUA5/yciO/yrdC domain Mmwyl1_0732 220 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 152995421 Common - TonB-dependent copper receptor Mmwyl1_1392 92 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 152995630 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1602 125 COG1609 PurR, Transcriptional regulators Transcription 152995999 Common - Arginine deiminase Mmwyl1_1975 51 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 152997986 Common - Ppx/GppA phosphatase Mmwyl1_3990 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 152994270 Common - ABC transporter related Mmwyl1_0228 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152997497 Common - diguanylate cyclase Mmwyl1_3494 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152995843 Common - ABC transporter related Mmwyl1_1819 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152998470 Common - AraC-type transcriptional regulator domain protein Mmwyl1_4475 135 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995178 Common - OmpA/MotB domain protein Mmwyl1_1149 138 COG1360 MotB, Flagellar motor protein Cell motility and secretion 152994179 Common - protein of unknown function DUF917 Mmwyl1_0137 10 COG3535 COG3535, Uncharacterized conserved protein Function unknown 152997103 Common - phenylacetate-CoA oxygenase, PaaI subunit Mmwyl1_3093 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 152996111 Common - major facilitator superfamily MFS_1 Mmwyl1_2089 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152998463 Common - ATP synthase F0, A subunit Mmwyl1_4468 200 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 152994782 Common - DSBA oxidoreductase Mmwyl1_0748 67 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 152998353 Nonpathogen - hypothetical protein Mmwyl1_4358 1 None None None 152995469 Common - hypothetical protein Mmwyl1_1440 53 COG4327 COG4327, Predicted membrane protein Function unknown 152996370 Common - sodium/hydrogen exchanger Mmwyl1_2348 203 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 152997287 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3282 131 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997441 Common - flagellar basal body-associated protein FliL Mmwyl1_3438 13 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 152998477 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_4482 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 152996712 Common - Xanthine dehydrogenase small subunit Mmwyl1_2699 122 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 152997643 Common - phosphoesterase PA-phosphatase related Mmwyl1_3641 21 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 152998383 Common - NAD-dependent epimerase/dehydratase Mmwyl1_4388 96 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152995996 Common - hypothetical protein Mmwyl1_1972 3 None None None 152995603 Common - Enoyl-CoA hydratase/isomerase Mmwyl1_1575 157 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 152995106 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Mmwyl1_1075 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 152997680 Common - S-formylglutathione hydrolase Mmwyl1_3679 102 COG0627 COG0627, Predicted esterase General function prediction only 152998010 Common - poly(A) polymerase Mmwyl1_4014 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 152997145 Common - Choline dehydrogenase Mmwyl1_3136 106 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 152995175 Common - Polyprenyl synthetase Mmwyl1_1146 233 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 152996773 Common - sarcosine oxidase, beta subunit family Mmwyl1_2760 128 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152995285 Common - Nucleoside-triphosphate--adenylate kinase Mmwyl1_1256 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 152995263 Common - transposase Mmwyl1_1234 9 None None None 152998244 Common - excinuclease ABC, A subunit Mmwyl1_4249 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 152995212 Common - Rhs element Vgr protein Mmwyl1_1183 63 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 152998022 Common - transcriptional regulator, AraC family Mmwyl1_4026 116 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996767 Common - esterase/lipase/thioesterase family protein Mmwyl1_2754 106 COG0657 Aes, Esterase/lipase Lipid metabolism 152996508 Common - ABC transporter related Mmwyl1_2487 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 152995663 Common - ABC transporter related Mmwyl1_1636 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152996551 Common - recombination protein RecR Mmwyl1_2532 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 152996095 Common - peptidase M14 carboxypeptidase A Mmwyl1_2073 29 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 152997064 Common - 3-oxoacid CoA-transferase, B subunit Mmwyl1_3054 101 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 152997679 Common - cobyric acid synthase CobQ Mmwyl1_3678 152 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 152995325 Common - Rieske (2Fe-2S) domain protein Mmwyl1_1296 74 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 152996566 Common - 3-hydroxyisobutyrate dehydrogenase Mmwyl1_2547 170 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 152995066 Nonpathogen - hypothetical protein Mmwyl1_1035 1 None None None 152998133 Common - Mg2 transporter protein CorA family protein Mmwyl1_4137 99 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 152996075 Common - hypothetical protein Mmwyl1_2053 19 None None None 152997407 Common - protein of unknown function UPF0270 Mmwyl1_3404 30 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 152995434 Common - phosphoenolpyruvate synthase Mmwyl1_1405 237 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 152995554 Common - peptidase U32 Mmwyl1_1526 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 152997668 Common - protein of unknown function DUF1653 Mmwyl1_3667 34 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 152998009 Common - putative two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_4013 173 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152996667 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_2654 32 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 152996376 Common - septum site-determining protein MinC Mmwyl1_2354 107 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 152996387 Nonpathogen - hypothetical protein Mmwyl1_2365 1 None None None 152994375 Common - transcriptional regulator, LysR family Mmwyl1_0337 151 COG0583 LysR, Transcriptional regulator Transcription 152997842 Common - diguanylate cyclase with PAS/PAC sensor Mmwyl1_3843 186 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152995826 Common - two component transcriptional regulator, winged helix family Mmwyl1_1802 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152996125 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Mmwyl1_2103 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 152997622 Common - hypothetical protein Mmwyl1_3620 30 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 152994395 Common - multi-sensor hybrid histidine kinase Mmwyl1_0357 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995368 Common - phospholipase D/Transphosphatidylase Mmwyl1_1339 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 152994393 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Mmwyl1_0355 216 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 152997755 Common - extracellular solute-binding protein family 1 Mmwyl1_3754 111 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152995658 Common - Non-ribosomal peptide synthetase Mmwyl1_1631 44 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152996161 Common - Auxin Efflux Carrier Mmwyl1_2139 75 COG0679 COG0679, Predicted permeases General function prediction only 152996353 Common - putative lipoprotein Mmwyl1_2331 6 None None None 152996586 Common - amino acid adenylation domain Mmwyl1_2569 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152997467 Common - ribosomal protein S18 Mmwyl1_3464 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 152994694 Common - Anthranilate synthase Mmwyl1_0660 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 152996944 Common - integral membrane protein, PqiA family Mmwyl1_2933 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 152994986 Common - urease, beta subunit Mmwyl1_0955 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 152996640 Common - tRNA synthetase class II (G H P and S) Mmwyl1_2627 198 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 152996272 Common - Radical SAM domain protein Mmwyl1_2250 39 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 152996900 Common - putative exonuclease RdgC Mmwyl1_2888 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 152994354 Common - hypothetical protein Mmwyl1_0313 2 None None None 152998349 Common - hypothetical protein Mmwyl1_4354 2 None None None 152997995 Common - Polyphosphate kinase Mmwyl1_3999 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 152994811 Common - extracellular solute-binding protein family 1 Mmwyl1_0777 79 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996291 Common - aminotransferase class IV Mmwyl1_2269 144 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 152996269 Common - putative methylamine utilization protein MauG precursor Mmwyl1_2247 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 152994089 Common - transcriptional regulator, LysR family Mmwyl1_0046 169 COG0583 LysR, Transcriptional regulator Transcription 152996212 Common - Holliday junction DNA helicase RuvB Mmwyl1_2190 230 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 152994601 Common - hypothetical protein Mmwyl1_0566 12 None None None 152994518 Common - filamentous haemagglutinin family outer membrane protein Mmwyl1_0481 187 None None None 152996192 Common - cob(I)alamin adenosyltransferase Mmwyl1_2170 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 152994154 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0112 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994753 Common - transcriptional regulator, LysR family Mmwyl1_0719 182 COG0583 LysR, Transcriptional regulator Transcription 152996979 Common - NUDIX hydrolase Mmwyl1_2968 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 152997424 Common - Cobyrinic acid ac-diamide synthase Mmwyl1_3421 231 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 152998217 Common - phage integrase family protein Mmwyl1_4222 3 None None None 152997951 Common - transcriptional regulator, DeoR family Mmwyl1_3954 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 152996276 Common - major facilitator superfamily MFS_1 Mmwyl1_2254 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996649 Common - protein of unknown function UPF0079 Mmwyl1_2636 205 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 152997686 Common - aspartate racemase Mmwyl1_3685 82 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 152995354 Common - amino acid permease-associated region Mmwyl1_1325 186 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 152996419 Common - Stringent starvation protein B Mmwyl1_2397 64 COG2969 SspB, Stringent starvation protein B General function prediction only 152997475 Common - thiamine ABC transporter, periplasmic binding protein Mmwyl1_3472 69 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 152996384 Common - Pectate lyase Mmwyl1_2362 5 None None None 152997763 Common - diguanylate cyclase Mmwyl1_3762 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996089 Common - Putative ParB-like nuclease Mmwyl1_2067 7 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 152997096 Common - class II aldolase/adducin family protein Mmwyl1_3086 72 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 152998180 Common - small-conductance mechanosensitive channel Mmwyl1_4184 11 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 152998421 Common - Alcohol dehydrogenase zinc-binding domain protein Mmwyl1_4426 191 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 152996259 Common - CBS domain containing protein Mmwyl1_2237 16 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 152994080 Common - Mandelate racemase/muconate lactonizing protein Mmwyl1_0037 112 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 152994291 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_0249 221 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 152997373 Nonpathogen - hypothetical protein Mmwyl1_3370 1 None None None 152997585 Common - flagellar basal-body rod protein FlgB Mmwyl1_3583 94 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 152996687 Common - maleylacetoacetate isomerase Mmwyl1_2674 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152994131 Common - ubiquinol oxidase, subunit II Mmwyl1_0089 106 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 152996605 Common - phenylalanyl-tRNA synthetase, beta subunit Mmwyl1_2592 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 152997037 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Mmwyl1_3026 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152997340 Common - fimbrial biogenesis outer membrane usher protein Mmwyl1_3335 34 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 152995125 Common - extracellular solute-binding protein family 1 Mmwyl1_1094 91 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996638 Common - two component transcriptional regulator, winged helix family Mmwyl1_2625 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152997808 Common - peptidase M16 domain protein Mmwyl1_3809 187 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 152996021 Common - hypothetical protein Mmwyl1_1999 9 None None None 152994975 Common - GCN5-related N-acetyltransferase Mmwyl1_0944 21 COG0456 RimI, Acetyltransferases General function prediction only 152995632 Common - Inositol-phosphate phosphatase Mmwyl1_1604 203 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 152994446 Common - phage shock protein C, PspC Mmwyl1_0408 10 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 152995018 Common - protein of unknown function DUF404 Mmwyl1_0987 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 152994503 Common - ABC transporter related Mmwyl1_0466 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152995875 Common - regulatory protein ArsR Mmwyl1_1851 150 COG0640 ArsR, Predicted transcriptional regulators Transcription 152996983 Common - transposase IS3/IS911 family protein Mmwyl1_2972 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152994524 Nonpathogen - hypothetical protein Mmwyl1_0487 3 None None None 152998252 Common - ribosomal protein L15 Mmwyl1_4257 195 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 152994611 Nonpathogen - hypothetical protein Mmwyl1_0576 6 None None None 152994280 Common - 67 kDa myosin-cross-reactive antigen family protein Mmwyl1_0238 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 152998213 Nonpathogen - hypothetical protein Mmwyl1_4218 1 None None None 152995742 Common - NADH:ubiquinone oxidoreductase, subunit F Mmwyl1_1716 160 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 152997116 Common - Tagatose-6-phosphate kinase Mmwyl1_3106 36 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 152997190 Common - drug resistance transporter, Bcr/CflA subfamily Mmwyl1_3182 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996817 Common - citrate synthase I Mmwyl1_2805 194 COG0372 GltA, Citrate synthase Energy production and conversion 152995171 Common - transcriptional regulator, LysR family Mmwyl1_1142 184 COG0583 LysR, Transcriptional regulator Transcription 152995155 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Mmwyl1_1124 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 152995746 Common - phosphoribosyltransferase Mmwyl1_1720 154 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 152997033 Common - coenzyme A transferase Mmwyl1_3022 107 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 152995329 Common - Septum formation initiator Mmwyl1_1300 56 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 152995340 Common - transcriptional regulator, LysR family Mmwyl1_1311 145 COG0583 LysR, Transcriptional regulator Transcription 152996394 Nonpathogen - hypothetical protein Mmwyl1_2372 1 None None None 152994174 Common - Pectate lyase/Amb allergen Mmwyl1_0132 19 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 152995628 Common - hypothetical protein Mmwyl1_1600 17 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 152997635 Common - transcriptional regulator, LysR family Mmwyl1_3633 165 COG0583 LysR, Transcriptional regulator Transcription 152998075 Common - glycoside hydrolase family 13 domain protein Mmwyl1_4079 16 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 152997213 Common - Domain of unknown function DUF1814 Mmwyl1_3205 11 COG2253 COG2253, Uncharacterized conserved protein Function unknown 152996007 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1984 130 COG1609 PurR, Transcriptional regulators Transcription 152996218 Common - Tol-Pal system YbgF Mmwyl1_2196 96 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 152995039 Common - transport system permease protein Mmwyl1_1008 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152996293 Common - aminotransferase class I and II Mmwyl1_2271 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152994387 Common - hypothetical protein Mmwyl1_0349 24 None None None 152996207 Common - transcriptional regulator, MarR family Mmwyl1_2185 28 COG1846 MarR, Transcriptional regulators Transcription 152997445 Nonpathogen - hypothetical protein Mmwyl1_3442 1 None None None 152997919 Common - transcriptional regulator, LysR family Mmwyl1_3922 181 COG0583 LysR, Transcriptional regulator Transcription 152994821 Common - type I secretion membrane fusion protein, HlyD family Mmwyl1_0787 146 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 152994824 Common - hypothetical protein Mmwyl1_0790 9 None None None 152994934 Common - hypothetical protein Mmwyl1_0902 9 None None None 152994683 Common - sulfate ABC transporter, ATPase subunit Mmwyl1_0649 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 152995126 Common - protein of unknown function DUF339 Mmwyl1_1095 39 COG2938 COG2938, Uncharacterized conserved protein Function unknown 152994385 Common - hypothetical protein Mmwyl1_0347 31 None None None 152994480 Common - Endoribonuclease L-PSP Mmwyl1_0443 141 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152998089 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4093 170 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152998170 Common - L-fuculose-phosphate aldolase Mmwyl1_4174 142 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 152995229 Common - protein of unknown function DUF1305 Mmwyl1_1200 45 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 152995696 Common - outer membrane efflux protein Mmwyl1_1670 64 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152994120 Common - KAP P-loop domain protein Mmwyl1_0078 29 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 152997751 Common - conserved hypothetical protein 95 Mmwyl1_3750 140 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 152995322 Common - hypothetical protein Mmwyl1_1293 44 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 152995372 Common - transcriptional regulator, BadM/Rrf2 family Mmwyl1_1343 171 COG1959 COG1959, Predicted transcriptional regulator Transcription 152997550 Common - CRISPR-associated protein, Cse1 family Mmwyl1_3547 18 None None None 152996912 Nonpathogen - hypothetical protein Mmwyl1_2901 1 None None None 152996782 Common - major facilitator superfamily MFS_1 Mmwyl1_2769 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152997120 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_3110 100 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152998433 Common - class II aldolase/adducin family protein Mmwyl1_4438 122 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 152996307 Common - glycine dehydrogenase Mmwyl1_2285 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 152994205 Nonpathogen - hypothetical protein Mmwyl1_0163 2 None None None 152995496 Nonpathogen - Sporulation domain protein Mmwyl1_1467 9 None None None 152997040 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_3029 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 152996320 Common - Threonyl/alanyl tRNA synthetase SAD Mmwyl1_2298 186 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 152998338 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4343 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152996637 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_2624 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995231 Common - hypothetical protein Mmwyl1_1202 24 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 152997513 Common - Sterol desaturase Mmwyl1_3510 77 COG3000 ERG3, Sterol desaturase Lipid metabolism 152996325 Common - pseudouridine synthase, RluA family Mmwyl1_2303 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 152994117 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0075 77 None None None 152997506 Common - TatD-related deoxyribonuclease Mmwyl1_3503 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 152994950 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_0919 99 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996155 Common - acyl carrier protein Mmwyl1_2133 176 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152997809 Common - TonB-dependent receptor plug Mmwyl1_3810 29 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 152998358 Common - HipA domain protein Mmwyl1_4363 46 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 152994912 Common - hypothetical protein Mmwyl1_0880 15 COG5453 COG5453, Uncharacterized conserved protein Function unknown 152995308 Common - putative membrane-associated zinc metalloprotease Mmwyl1_1279 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 152994580 Common - diguanylate cyclase Mmwyl1_0544 26 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152997910 Common - Xylose isomerase domain protein TIM barrel Mmwyl1_3913 81 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 152994233 Common - hypothetical protein Mmwyl1_0191 84 COG1738 COG1738, Uncharacterized conserved protein Function unknown 152995590 Common - two component transcriptional regulator, winged helix family Mmwyl1_1562 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152998366 Common - hypothetical protein Mmwyl1_4371 61 COG3943 COG3943, Virulence protein General function prediction only 152996527 Common - phage P2 GpU family protein Mmwyl1_2508 18 COG3499 COG3499, Phage protein U General function prediction only 152997932 Common - Rhodanese domain protein Mmwyl1_3935 29 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 152996719 Common - YcfA family protein Mmwyl1_2706 6 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 152996445 Common - Methionine sulfoxide reductase B Mmwyl1_2423 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 152997971 Nonpathogen - hypothetical protein Mmwyl1_3975 2 None None None 152998177 Common - acetoacetyl-CoA synthase Mmwyl1_4181 205 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 152997709 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_3708 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 152997831 Common - Tetratricopeptide TPR_2 repeat protein Mmwyl1_3832 16 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 152995893 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_1869 73 COG1609 PurR, Transcriptional regulators Transcription 152997869 Common - OmpA domain protein transmembrane region-containing protein Mmwyl1_3870 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 152995677 Common - extracellular solute-binding protein family 1 Mmwyl1_1651 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152998426 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4431 158 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152994255 Common - hypothetical protein Mmwyl1_0213 12 None None None 152994618 Common - putative phage head completeion protein Mmwyl1_0583 11 None None None 152994992 Common - integral membrane sensor hybrid histidine kinase Mmwyl1_0961 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152994743 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0709 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152995396 Common - protein of unknown function DUF1304 Mmwyl1_1367 35 COG3759 COG3759, Predicted membrane protein Function unknown 152998241 Common - Smr protein/MutS2 Mmwyl1_4246 96 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 152994780 Common - ubiquinone/menaquinone biosynthesis methyltransferase Mmwyl1_0746 220 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152994576 Common - Holliday junction resolvase YqgF Mmwyl1_0540 183 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 152995869 Common - band 7 protein Mmwyl1_1845 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 152996311 Common - aldehyde dehydrogenase Mmwyl1_2289 208 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994106 Common - Helix-turn-helix type 11 domain protein Mmwyl1_0064 84 COG2378 COG2378, Predicted transcriptional regulator Transcription 152994186 Common - FAD linked oxidase domain protein Mmwyl1_0144 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 152997988 Common - oxidoreductase FAD/NAD(P)-binding domain protein Mmwyl1_3992 98 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 152997704 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_3703 126 COG1609 PurR, Transcriptional regulators Transcription 152995452 Common - transcriptional regulator, TetR family Mmwyl1_1423 61 COG1309 AcrR, Transcriptional regulator Transcription 152998286 Common - putative transcriptional acitvator, Baf family Mmwyl1_4291 137 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 152996131 Common - glutaminyl-tRNA synthetase Mmwyl1_2109 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 152998200 Nonpathogen - hypothetical protein Mmwyl1_4204 1 None None None 152997129 Common - hypothetical protein Mmwyl1_3119 12 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 152994138 Common - transcriptional regulator, MarR family Mmwyl1_0096 92 COG1846 MarR, Transcriptional regulators Transcription 152994605 Common - hypothetical protein Mmwyl1_0570 10 None None None 152997509 Common - RNA methyltransferase, TrmH family, group 1 Mmwyl1_3506 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 152998000 Common - putative cold-shock DNA-binding domain protein Mmwyl1_4004 148 COG1278 CspC, Cold shock proteins Transcription 152997499 Common - Lysozyme subfamily 2 Mmwyl1_3496 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 152997434 Common - flagellar biosynthetic protein FlhB Mmwyl1_3431 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 152994264 Common - putative transcriptional regulator, AsnC family Mmwyl1_0222 32 COG1522 Lrp, Transcriptional regulators Transcription 152995725 Common - transcriptional regulator, LysR family Mmwyl1_1699 186 COG0583 LysR, Transcriptional regulator Transcription 152996116 Common - aspartate-semialdehyde dehydrogenase Mmwyl1_2094 202 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 152996454 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2432 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996878 Common - glycosyl transferase group 1 Mmwyl1_2866 61 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152996941 Common - homocysteine S-methyltransferase Mmwyl1_2930 145 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 152994071 Common - oxidoreductase domain protein Mmwyl1_0028 157 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152996401 Common - protein of unknown function UPF0118 Mmwyl1_2379 137 COG0628 PerM, Predicted permease General function prediction only 152994250 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0208 18 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152996503 Common - Carboxymuconolactone decarboxylase Mmwyl1_2482 52 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 152996969 Common - putative transposase Mmwyl1_2958 31 None None None 152997836 Common - diguanylate cyclase Mmwyl1_3837 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152998209 Nonpathogen - prevent-host-death family protein Mmwyl1_4213 4 None None None 152995927 Common - NADPH-dependent FMN reductase Mmwyl1_1903 65 COG0431 COG0431, Predicted flavoprotein General function prediction only 152996537 Common - VacJ family lipoprotein Mmwyl1_2518 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 152995525 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Mmwyl1_1496 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 152995789 Common - Integrase catalytic region Mmwyl1_1763 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152994044 Common - chromosomal replication initiator protein DnaA Mmwyl1_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 152995373 Common - FeS assembly protein SufB Mmwyl1_1344 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 152994248 Common - diguanylate cyclase Mmwyl1_0206 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994067 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0024 188 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152996556 Common - type III restriction protein res subunit Mmwyl1_2537 154 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 152996561 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mmwyl1_2542 180 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 152996892 Common - glutamyl-tRNA synthetase Mmwyl1_2880 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 152994668 Common - inner-membrane translocator Mmwyl1_0634 110 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 152995757 Common - hypothetical protein Mmwyl1_1731 30 None None None 152998165 Common - PfkB domain protein Mmwyl1_4169 137 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 152994499 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0462 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994464 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0426 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995388 Common - Pyrrolo-quinoline quinone Mmwyl1_1359 115 COG1520 COG1520, FOG: WD40-like repeat Function unknown 152994732 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0698 107 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152996708 Nonpathogen - plasmid stabilization system Mmwyl1_2695 4 COG3668 ParE, Plasmid stabilization system protein General function prediction only 152994565 Common - hypothetical protein Mmwyl1_0529 2 None None None 152995819 Common - hypothetical protein Mmwyl1_1795 2 None None None 152996410 Common - thiazole biosynthesis protein ThiH Mmwyl1_2388 54 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 152998015 Common - hypothetical protein Mmwyl1_4019 4 None None None 152996122 Nonpathogen - hypothetical protein Mmwyl1_2100 1 None None None 152996865 Common - protein of unknown function UPF0066 Mmwyl1_2853 89 COG1720 COG1720, Uncharacterized conserved protein Function unknown 152997518 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3515 178 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 152995217 Nonpathogen - hypothetical protein Mmwyl1_1188 1 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 152996495 Common - succinic semialdehyde dehydrogenase Mmwyl1_2474 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994647 Common - protein of unknown function UPF0052 and CofD Mmwyl1_0613 81 COG0391 COG0391, Uncharacterized conserved protein Function unknown 152995655 Common - transport system permease protein Mmwyl1_1628 122 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 152998059 Common - transcriptional regulator, LysR family Mmwyl1_4063 98 COG0583 LysR, Transcriptional regulator Transcription 152995299 Common - metal dependent phosphohydrolase Mmwyl1_1270 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 152996849 Nonpathogen - hypothetical protein Mmwyl1_2837 1 None None None 152997355 Common - Transcriptional regulator IclR Mmwyl1_3350 108 COG1414 IclR, Transcriptional regulator Transcription 152996614 Common - transcriptional regulator, XRE family Mmwyl1_2601 101 COG1396 HipB, Predicted transcriptional regulators Transcription 152996722 Common - Hydroxyisourate hydrolase Mmwyl1_2709 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 152996420 Common - Glutathione S-transferase domain Mmwyl1_2398 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152995559 Common - ribonuclease T Mmwyl1_1531 64 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 152996368 Common - uncharacterised conserved protein UCP030820 Mmwyl1_2346 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 152996013 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_1990 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152996935 Nonpathogen - Transglycosylase-associated protein Mmwyl1_2924 1 COG2261 COG2261, Predicted membrane protein Function unknown 152996061 Common - Tfp pilus assembly protein FimV-like protein Mmwyl1_2039 37 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 152994132 Common - Cytochrome o ubiquinol oxidase subunit I Mmwyl1_0090 166 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 152997183 Common - response regulator receiver protein Mmwyl1_3175 89 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152994340 Common - hypothetical protein Mmwyl1_0299 73 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152994165 Common - beta-lactamase-like protein Mmwyl1_0123 17 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 152994269 Common - diguanylate phosphodiesterase Mmwyl1_0227 160 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152998061 Common - hypothetical protein Mmwyl1_4065 6 None None None 152994373 Common - deoxyribodipyrimidine photolyase-related protein Mmwyl1_0335 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 152995357 Common - glutamate-1-semialdehyde-2,1-aminomutase Mmwyl1_1328 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 152996068 Common - Sporulation domain protein Mmwyl1_2046 14 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 152995737 Common - NADH:ubiquinone oxidoreductase, subunit A Mmwyl1_1711 45 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 152994151 Common - major facilitator superfamily MFS_1 Mmwyl1_0109 7 None None None 152997924 Common - transcriptional regulator, LysR family Mmwyl1_3927 189 COG0583 LysR, Transcriptional regulator Transcription 152995073 Common - DNA primase Mmwyl1_1042 217 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 152997334 Common - putative transcriptional regulator, MerR family Mmwyl1_3329 144 COG0789 SoxR, Predicted transcriptional regulators Transcription 152998046 Common - riboflavin biosynthesis protein RibD Mmwyl1_4050 225 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 152994885 Common - periplasmic binding protein Mmwyl1_0853 130 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 152996429 Common - ATP phosphoribosyltransferase Mmwyl1_2407 207 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 152997160 Common - hypothetical protein Mmwyl1_3151 5 None None None 152995768 Common - transposase IS116/IS110/IS902 family protein Mmwyl1_1742 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 152996483 Common - Glutathione peroxidase Mmwyl1_2461 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 152997857 Common - precorrin 3B synthase CobZ Mmwyl1_3858 59 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 152996797 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_2784 115 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152998080 Common - heat shock protein DnaJ domain protein Mmwyl1_4084 16 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 152995403 Common - precorrin-3B C17-methyltransferase Mmwyl1_1374 118 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 152998296 Common - TonB-dependent receptor Mmwyl1_4301 55 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 152994703 Common - GCN5-related N-acetyltransferase Mmwyl1_0669 64 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 152998197 Nonpathogen - hypothetical protein Mmwyl1_4201 2 None None None 152996899 Common - Thymidine kinase Mmwyl1_2887 95 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 152996340 Common - response regulator receiver protein Mmwyl1_2318 120 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152998030 Common - carbamoyl-phosphate synthase, large subunit Mmwyl1_4034 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 152994492 Common - amidase, hydantoinase/carbamoylase family Mmwyl1_0455 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152997170 Common - protein of unknown function DUF112 transmembrane Mmwyl1_3162 78 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152995968 Common - hypothetical protein Mmwyl1_1944 15 COG4925 COG4925, Uncharacterized conserved protein Function unknown 152998038 Common dddT choline/carnitine/betaine transporter Mmwyl1_4042 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 152995977 Common - transaldolase Mmwyl1_1953 59 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 152995973 Nonpathogen - hypothetical protein Mmwyl1_1949 3 COG3462 COG3462, Predicted membrane protein Function unknown 152997026 Common - Electron transfer flavoprotein alpha/beta-subunit Mmwyl1_3015 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 152997535 Common - Monosaccharide-transporting ATPase Mmwyl1_3532 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152995151 Common - NUDIX hydrolase Mmwyl1_1120 35 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 152995983 Common - ATP synthase F0, C subunit Mmwyl1_1959 84 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 152995005 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0974 125 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152997651 Common - cytochrome c class I Mmwyl1_3650 46 COG3245 CycB, Cytochrome c5 Energy production and conversion 152995988 Common - heat shock protein DnaJ domain protein Mmwyl1_1964 230 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 152994552 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0516 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152998052 Common - putative transcriptional regulator, AsnC family Mmwyl1_4056 153 COG1522 Lrp, Transcriptional regulators Transcription 152994728 Common - regulatory protein LacI Mmwyl1_0694 128 COG1609 PurR, Transcriptional regulators Transcription 152998224 Common - lipoprotein signal peptidase Mmwyl1_4229 206 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152995934 Common - protein of unknown function DUF112 transmembrane Mmwyl1_1910 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152997939 Common - 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase Mmwyl1_3942 59 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 152996335 Common - type II secretion system protein E Mmwyl1_2313 169 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 152997225 Common - competence protein ComEA helix-hairpin-helix repeat protein Mmwyl1_3219 76 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 152994654 Common - transcriptional regulator, TetR family Mmwyl1_0620 68 COG1309 AcrR, Transcriptional regulator Transcription 152997328 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3323 111 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994057 Common - TrkA-N domain protein Mmwyl1_0014 143 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 152996675 Common - glycosyl transferase family 2 Mmwyl1_2662 147 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 152995437 Common - RNA methyltransferase, TrmH family, group 3 Mmwyl1_1408 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 152994451 Common - transcriptional regulator, LysR family Mmwyl1_0413 178 COG0583 LysR, Transcriptional regulator Transcription 152995666 Common - hypothetical protein Mmwyl1_1639 6 None None None 152994487 Common - transcriptional regulator, RpiR family Mmwyl1_0450 59 COG1737 RpiR, Transcriptional regulators Transcription 152998382 Common - putative endoribonuclease L-PSP Mmwyl1_4387 187 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152998273 Common - translation elongation factor Tu Mmwyl1_4278 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 152996139 Common - SOS-response transcriptional repressor, LexA Mmwyl1_2117 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 152994535 Nonpathogen - hypothetical protein Mmwyl1_0499 5 None None None 152995640 Common - L-fucose transporter Mmwyl1_1612 46 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 152996254 Common - adenine phosphoribosyltransferase Mmwyl1_2232 197 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 152997047 Nonpathogen - hypothetical protein Mmwyl1_3036 1 None None None 152994310 Common - hypothetical protein Mmwyl1_0268 20 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152996077 Common - molecular chaperone Mmwyl1_2055 226 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 152994128 Common - hypothetical protein Mmwyl1_0086 28 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 152997394 Common - histidine kinase Mmwyl1_3391 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997084 Common - extracellular solute-binding protein family 5 Mmwyl1_3074 180 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152995408 Common - hypothetical protein Mmwyl1_1379 3 None None None 152995441 Common - protein of unknown function UPF0126 Mmwyl1_1412 133 COG2860 COG2860, Predicted membrane protein Function unknown 152994331 Common - multiple antibiotic resistance (MarC)-related protein Mmwyl1_0290 81 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 152994095 Common - Dihydrodipicolinate synthase Mmwyl1_0053 201 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 152994760 Common - protein of unknown function DUF610 YibQ Mmwyl1_0726 64 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 152996770 Common - Sarcosine oxidase gamma subunit Mmwyl1_2757 28 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 152995504 Nonpathogen - hypothetical protein Mmwyl1_1475 1 None None None 152997615 Common - Glutathione S-transferase domain Mmwyl1_3613 36 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152995034 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_1003 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 152994864 Common - TDP-4-keto-6-deoxy-D-glucose transaminase Mmwyl1_0832 195 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 152996472 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_2450 15 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152996058 Common - chaperonin Cpn10 Mmwyl1_2036 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 152996974 Nonpathogen - hypothetical protein Mmwyl1_2963 1 None None None 152998303 Common - extracellular solute-binding protein family 1 Mmwyl1_4308 122 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 152994774 Common - Pectinesterase Mmwyl1_0740 21 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 152994835 Common - UDP-N-acetylglucosamine 2-epimerase Mmwyl1_0801 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 152996595 Nonpathogen - hypothetical protein Mmwyl1_2580 2 None None None 152996703 Common - CRISPR-associated RAMP protein, Cmr4 family Mmwyl1_2690 33 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 152995601 Common - AMP-dependent synthetase and ligase Mmwyl1_1573 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152997964 Common - ferric uptake regulator, Fur family Mmwyl1_3967 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 152996093 Common - regulator of ribonuclease activity A Mmwyl1_2071 92 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 152997419 Common - hypothetical protein Mmwyl1_3416 9 COG3889 COG3889, Predicted solute binding protein General function prediction only 152996066 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Mmwyl1_2044 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 152996209 Common - aspartyl-tRNA synthetase Mmwyl1_2187 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152998344 Common - extracellular solute-binding protein family 1 Mmwyl1_4349 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152998207 Common - hypothetical protein Mmwyl1_4211 10 None None None 152998246 Common - DNA-directed RNA polymerase, alpha subunit Mmwyl1_4251 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 152997443 Common - response regulator receiver protein Mmwyl1_3440 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152995896 Common - putative lipoprotein Mmwyl1_1872 10 COG5618 COG5618, Predicted periplasmic lipoprotein General function prediction only 152997452 Common - flagellar hook-basal body complex subunit FliE Mmwyl1_3449 82 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 152997768 Common - ribosomal protein L19 Mmwyl1_3767 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 152996107 Common - peptidase M48 Ste24p Mmwyl1_2085 120 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 152998443 Common - sulfatase Mmwyl1_4448 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 152997633 Common - regulatory protein RecX Mmwyl1_3631 114 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 152997422 Common - putative CheW protein Mmwyl1_3419 139 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 152996724 Common - regulatory protein ArsR Mmwyl1_2711 15 COG4189 COG4189, Predicted transcriptional regulator Transcription 152996691 Common - transcriptional regulator, LysR family Mmwyl1_2678 179 COG0583 LysR, Transcriptional regulator Transcription 152995916 Common - DEAD/DEAH box helicase domain protein Mmwyl1_1892 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152997875 Common - phosphopantetheine-binding Mmwyl1_3876 31 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152997718 Common - nucleoside recognition domain protein Mmwyl1_3717 17 COG0700 SpmB, Uncharacterized membrane protein Function unknown 152998122 Common - primosomal protein N' Mmwyl1_4126 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 152997074 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_3064 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 152995776 Common - protein of unknown function DUF446 Mmwyl1_1750 29 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 152997549 Common - CRISPR-associated protein, Cse2 family Mmwyl1_3546 9 None None None 152994696 Common - hypothetical protein Mmwyl1_0662 15 None None None 152995040 Common - periplasmic binding protein Mmwyl1_1009 52 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 152995535 Common - cyd operon protein YbgT Mmwyl1_1507 17 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 152997818 Common - peptidase M20 Mmwyl1_3819 98 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152994905 Common - ABC-2 type transporter Mmwyl1_0873 145 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 152997140 Common - protein of unknown function DUF1486 Mmwyl1_3131 17 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 152997010 Common - CDP-alcohol phosphatidyltransferase Mmwyl1_2999 43 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 152996350 Common - two component transcriptional regulator, winged helix family Mmwyl1_2328 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152997487 Nonpathogen - hypothetical protein Mmwyl1_3484 1 None None None 152994928 Common - amidohydrolase Mmwyl1_0896 181 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 152995143 Common - ABC transporter related Mmwyl1_1112 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 152995950 Common - ABC transporter related Mmwyl1_1926 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 152994859 Common - hypothetical protein Mmwyl1_0827 19 None None None 152997829 Common - putative transcriptional activator, TenA family Mmwyl1_3830 26 COG0819 TenA, Putative transcription activator Transcription 152996222 Common - hypothetical protein Mmwyl1_2200 22 None None None 152995030 Common - phosphonate ABC transporter, inner membrane subunit Mmwyl1_0999 99 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 152997992 Common - Hsp33 protein Mmwyl1_3996 138 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 152995062 Common - Polyribonucleotide nucleotidyltransferase Mmwyl1_1031 245 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 152997916 Common - Shikimate dehydrogenase substrate binding domain protein Mmwyl1_3919 222 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 152997594 Common - Uroporphyrinogen III synthase HEM4 Mmwyl1_3592 75 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 152994195 Common - FAD dependent oxidoreductase Mmwyl1_0153 134 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152996888 Common - hypothetical protein Mmwyl1_2876 3 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997380 Common - Precorrin-6A reductase Mmwyl1_3377 73 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 152996256 Common - oxygen-independent coproporphyrinogen III oxidase Mmwyl1_2234 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 152996584 Common - putative transposase Mmwyl1_2566 35 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152994621 Common - hypothetical protein Mmwyl1_0586 22 None None None 152997270 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Mmwyl1_3265 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 152995047 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mmwyl1_1016 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 152995486 Common - response regulator receiver protein Mmwyl1_1457 81 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 152996289 Common - dTMP kinase Mmwyl1_2267 227 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 152994903 Common - PEBP family protein Mmwyl1_0871 120 COG1881 COG1881, Phospholipid-binding protein General function prediction only 152995880 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1856 131 COG1609 PurR, Transcriptional regulators Transcription 152995643 Common - glycoside hydrolase family 3 domain protein Mmwyl1_1615 178 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 152996329 Common - 2-oxo-acid dehydrogenase E1 subunit, homodimeric type Mmwyl1_2307 143 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 152994322 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_0281 14 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 152996650 Common - protein of unknown function DUF81 Mmwyl1_2637 76 COG0730 COG0730, Predicted permeases General function prediction only 152997941 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_3944 101 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152997798 Common - NADH/Ubiquinone/plastoquinone (complex I) Mmwyl1_3799 189 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 152995194 Common - hypothetical protein Mmwyl1_1165 8 None None None 152996842 Common - Pyridoxal phosphate biosynthetic protein PdxJ Mmwyl1_2830 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 152997249 Common - hypothetical protein Mmwyl1_3243 4 None None None 152994329 Common - efflux transporter, RND family, MFP subunit Mmwyl1_0288 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152995805 Common - hypothetical protein Mmwyl1_1780 33 COG3911 COG3911, Predicted ATPase General function prediction only 152997735 Common - DNA mismatch repair protein MutS Mmwyl1_3734 207 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 152994069 Common - regulatory protein LacI Mmwyl1_0026 126 COG1609 PurR, Transcriptional regulators Transcription 152994737 Common - methylenetetrahydrofolate reductase Mmwyl1_0703 20 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 152994730 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0696 124 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 152996493 Common - carbon storage regulator, CsrA Mmwyl1_2472 76 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 152996733 Nonpathogen - hypothetical protein Mmwyl1_2720 1 None None None 152996283 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_2261 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997796 Common - AFG1-family ATPase Mmwyl1_3797 96 COG1485 COG1485, Predicted ATPase General function prediction only 152998167 Common - inner-membrane translocator Mmwyl1_4171 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152996457 Common - 2OG-Fe(II) oxygenase Mmwyl1_2435 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 152994749 Common - protein-export protein SecB Mmwyl1_0715 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 152996510 Common - putative DNA-binding protein Mmwyl1_2489 13 None None None 152995682 Common - beta-Ig-H3/fasciclin Mmwyl1_1656 68 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 152996546 Common - glutamine amidotransferase class-II Mmwyl1_2527 70 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 152995375 Common - FeS assembly protein SufD Mmwyl1_1346 170 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 152995338 Common - hypothetical protein Mmwyl1_1309 5 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 152997311 Common - transposase Mmwyl1_3306 9 None None None 152997105 Common - phenylacetate-CoA oxygenase, PaaG subunit Mmwyl1_3095 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 152996497 Common - aldehyde dehydrogenase Mmwyl1_2476 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152995116 Common - glycine cleavage T protein (aminomethyl transferase) Mmwyl1_1085 95 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 152994984 Common - Urease accessory protein UreD Mmwyl1_0953 75 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 152998329 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Mmwyl1_4334 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 152995723 Common - protein of unknown function DUF1285 Mmwyl1_1697 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 152997960 Common - chaperone protein DnaJ Mmwyl1_3963 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 152998369 Common - DNA-cytosine methyltransferase Mmwyl1_4374 130 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 152996154 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Mmwyl1_2132 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152994277 Common - putative transcriptional regulator, AsnC family Mmwyl1_0235 156 COG1522 Lrp, Transcriptional regulators Transcription 152996173 Common - Biopolymer transport protein ExbD/TolR Mmwyl1_2151 41 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 152998399 Common - extracellular solute-binding protein family 5 Mmwyl1_4404 212 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 152997469 Common - MltA-interacting MipA family protein Mmwyl1_3466 28 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 152994598 Common - pentapeptide repeat protein Mmwyl1_0563 88 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 152997366 Common - hypothetical protein Mmwyl1_3362 6 None None None 152996904 Common - helicase domain protein Mmwyl1_2892 117 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 152997577 Common - flagellar rod assembly protein/muramidase FlgJ Mmwyl1_3575 68 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 152994177 Common - response regulator receiver modulated diguanylate cyclase Mmwyl1_0135 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152996379 Nonpathogen - ferredoxin Mmwyl1_2357 1 COG0633 Fdx, Ferredoxin Energy production and conversion 152995182 Common - Protein of unknown function DUF1722 Mmwyl1_1153 62 COG3272 COG3272, Uncharacterized conserved protein Function unknown 152997898 Common - histidine ammonia-lyase Mmwyl1_3901 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 152994923 Common - diguanylate cyclase Mmwyl1_0891 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996777 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2764 166 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152997285 Common - L-serine dehydratase 1 Mmwyl1_3280 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 152994431 Common - TonB-dependent receptor Mmwyl1_0393 114 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 152996194 Common - cyclic nucleotide-binding protein Mmwyl1_2172 5 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 152997180 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_3172 59 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152997387 Common - transcriptional regulator, LysR family Mmwyl1_3384 191 COG0583 LysR, Transcriptional regulator Transcription 152997438 Common - flagellar biosynthesis protein FliO Mmwyl1_3435 25 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 152997696 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_3695 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152998416 Common - succinic semialdehyde dehydrogenase Mmwyl1_4421 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996385 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Mmwyl1_2363 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 152997343 Nonpathogen - hypothetical protein Mmwyl1_3338 2 None None None 152998082 Common - TonB family protein Mmwyl1_4086 51 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 152995464 Common - putative transcriptional regulator, AsnC family Mmwyl1_1435 163 COG1522 Lrp, Transcriptional regulators Transcription 152998095 Common - MATE efflux family protein Mmwyl1_4099 148 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 152995472 Common - aminotransferase class V Mmwyl1_1443 198 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 152997237 Common - exodeoxyribonuclease V, alpha subunit Mmwyl1_3231 127 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 152994204 Common - protein of unknown function DUF1272 Mmwyl1_0162 24 COG3813 COG3813, Uncharacterized protein conserved in bacteria Function unknown 152996894 Nonpathogen - hypothetical protein Mmwyl1_2882 1 None None None 152996189 Common - aminopeptidase N Mmwyl1_2167 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 152997545 Common - hypothetical protein Mmwyl1_3542 13 None None None 152995887 Common - diguanylate cyclase Mmwyl1_1863 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152995096 Nonpathogen - FlgN family protein Mmwyl1_1065 2 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 152995067 Common - diguanylate cyclase Mmwyl1_1036 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152997524 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3521 219 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 152995856 Common - Amidase Mmwyl1_1832 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152995562 Common - PfkB domain protein Mmwyl1_1534 188 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 152996519 Common - phage P2 GpU family protein Mmwyl1_2500 19 COG3499 COG3499, Phage protein U General function prediction only 152994806 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Mmwyl1_0772 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 152994918 Common - Xylose isomerase domain protein TIM barrel Mmwyl1_0886 32 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 152996714 Common - NMT1/THI5 like domain protein Mmwyl1_2701 120 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 152994550 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0514 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152996564 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_2545 124 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152997958 Common - phosphoribulokinase/uridine kinase Mmwyl1_3961 80 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 152996278 Common - putative transcriptional regulator, MerR family Mmwyl1_2256 127 COG0789 SoxR, Predicted transcriptional regulators Transcription 152997261 Common - outer membrane lipoprotein carrier protein LolA Mmwyl1_3255 69 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 152994152 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_0110 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 152994990 Common - urease accessory protein UreG Mmwyl1_0959 135 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 152997150 Common - Rieske (2Fe-2S) domain protein Mmwyl1_3141 37 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 152996643 Common - HflK protein Mmwyl1_2630 215 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 152995192 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_1163 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152995582 Common - protein of unknown function DUF1499 Mmwyl1_1554 22 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 152994356 Common - Haem oxygenase Mmwyl1_0316 13 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 152996378 Common - nuclease SbcCD, D subunit Mmwyl1_2356 114 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 152997409 Common - cell division protein ZipA Mmwyl1_3406 45 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 152997819 Common - ABC transporter related Mmwyl1_3820 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 152995323 Common - hypothetical protein Mmwyl1_1294 3 None None None 152995836 Common - alkylhydroperoxidase like protein, AhpD family Mmwyl1_1812 79 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 152997062 Common - short chain fatty acid transporter Mmwyl1_3052 41 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 152994140 Common - drug resistance transporter, EmrB/QacA subfamily Mmwyl1_0098 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994527 Common - hypothetical protein Mmwyl1_0491 6 None None None 152994603 Common - hypothetical protein Mmwyl1_0568 3 None None None 152994149 Common - penicillin-binding protein 1C Mmwyl1_0107 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 152996351 Common - cytochrome c biogenesis protein transmembrane region Mmwyl1_2329 103 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 152998479 Common - tRNA modification GTPase TrmE Mmwyl1_4484 234 COG0486 ThdF, Predicted GTPase General function prediction only 152998020 Common - hypothetical protein Mmwyl1_4024 38 COG3177 COG3177, Uncharacterized conserved protein Function unknown 152997684 Nonpathogen - GCN5-related N-acetyltransferase Mmwyl1_3683 11 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152994932 Common - transcriptional regulator, LysR family Mmwyl1_0900 191 COG0583 LysR, Transcriptional regulator Transcription 152996793 Common - Glucuronate isomerase Mmwyl1_2780 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 152995100 Common - Protein-glutamate O-methyltransferase Mmwyl1_1069 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 152997902 Common - transcriptional regulator, GntR family Mmwyl1_3905 128 COG2188 PhnF, Transcriptional regulators Transcription 152994813 Common - Transcriptional regulator IclR Mmwyl1_0779 121 COG1414 IclR, Transcriptional regulator Transcription 152995611 Common - N-isopropylammelide isopropylaminohydrolase Mmwyl1_1583 74 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 152995139 Common - phenazine biosynthesis protein PhzF family Mmwyl1_1108 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 152994794 Common - flagellar basal body-associated protein FliL Mmwyl1_0760 17 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 152995821 Common - hypothetical protein Mmwyl1_1797 18 COG3673 COG3673, Uncharacterized conserved protein Function unknown 152996972 Common - NAD+ synthetase Mmwyl1_2961 227 COG0171 NadE, NAD synthase Coenzyme metabolism 152995251 Nonpathogen - hypothetical protein Mmwyl1_1222 2 None None None 152996342 Common - transcriptional regulator, GntR family Mmwyl1_2320 115 COG1802 GntR, Transcriptional regulators Transcription 152996274 Common - protein of unknown function UPF0187 Mmwyl1_2252 56 COG3781 COG3781, Predicted membrane protein Function unknown 152997203 Common - hypothetical protein Mmwyl1_3195 28 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 152994366 Common - nitroreductase Mmwyl1_0326 87 COG0778 NfnB, Nitroreductase Energy production and conversion 152995280 Common - cysteine synthase B Mmwyl1_1251 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 152997208 Common - N-6 DNA methylase Mmwyl1_3200 162 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 152996452 Common - hypothetical protein Mmwyl1_2430 15 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 152997880 Common - hypothetical protein Mmwyl1_3882 40 COG4258 COG4258, Predicted exporter General function prediction only 152996821 Common - phosphoribosylglycinamide formyltransferase Mmwyl1_2809 223 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 152995921 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Mmwyl1_1897 177 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 152995635 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1607 213 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 152994620 Common - phage major capsid protein, P2 family Mmwyl1_0585 22 None None None 152994391 Common - protein of unknown function DUF891 Mmwyl1_0353 23 COG4679 COG4679, Phage-related protein Function unknown 152994334 Common - ABC transporter related Mmwyl1_0293 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 152997641 Common - ABC transporter related Mmwyl1_3639 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152994241 Common - Na+/H+ antiporter NhaC Mmwyl1_0199 75 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 152995356 Common - Chloride channel core Mmwyl1_1327 121 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 152996803 Common - signal transduction histidine kinase regulating citrate/malate metabolism Mmwyl1_2790 100 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 152996133 Common - UspA domain protein Mmwyl1_2111 129 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 152998360 Common - hypothetical protein Mmwyl1_4365 2 None None None 152996673 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_2660 115 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995287 Common - putative undecaprenol kinase Mmwyl1_1258 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 152994790 Common - chromate transporter, chromate ion transporter (CHR) family Mmwyl1_0756 96 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 152996417 Common - protein of unknown function UPF0102 Mmwyl1_2395 121 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 152997997 Common - phosphoribosylformylglycinamidine synthase Mmwyl1_4001 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 152998012 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Mmwyl1_4016 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 152995349 Common - acetolactate synthase, small subunit Mmwyl1_1320 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 152997139 Common - Phenol hydroxylase domain protein dimerisation Mmwyl1_3129 67 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152994843 Common - Heparinase II/III family protein Mmwyl1_0809 52 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 152997661 Common - protein of unknown function DUF1289 Mmwyl1_3660 19 COG3313 COG3313, Predicted Fe-S protein General function prediction only 152997611 Common - ATPase AAA-2 domain protein Mmwyl1_3609 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 152995753 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Mmwyl1_1727 170 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 152995941 Common - hypothetical protein Mmwyl1_1917 5 None None None 152997670 Common - Arginine N-succinyltransferase Mmwyl1_3669 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 152994511 Common - hypothetical protein Mmwyl1_0474 11 None None None 152995576 Common - deoxycytidine triphosphate deaminase Mmwyl1_1548 99 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 152997748 Common - PTSINtr with GAF domain, PtsP Mmwyl1_3747 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 152996475 Common - hypothetical protein Mmwyl1_2453 23 None None None 152997377 Common - precorrin-2 C20-methyltransferase Mmwyl1_3374 187 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 152998465 Common - parB-like partition protein Mmwyl1_4470 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 152995011 Common - metal dependent phosphohydrolase Mmwyl1_0980 107 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 152994777 Common - twin-arginine translocation protein, TatA/E family subunit Mmwyl1_0743 53 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 152994591 Common - hypothetical protein Mmwyl1_0555 10 None None None 152994675 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mmwyl1_0641 139 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 152996030 Common - Transcriptional regulator IclR Mmwyl1_2008 122 COG1414 IclR, Transcriptional regulator Transcription 152995567 Common - endonuclease III Mmwyl1_1539 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 152997410 Common - Tetratricopeptide TPR_2 repeat protein Mmwyl1_3407 26 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 152995108 Common - methylglyoxal synthase Mmwyl1_1077 82 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 152996680 Common - transcriptional regulator, LysR family Mmwyl1_2667 117 COG0583 LysR, Transcriptional regulator Transcription 152997725 Nonpathogen - antibiotic biosynthesis monooxygenase domain protein Mmwyl1_3724 5 None None None 152995130 Nonpathogen - hypothetical protein Mmwyl1_1099 1 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 152994090 Common - 4-aminobutyrate aminotransferase Mmwyl1_0047 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 152997601 Common - peptide chain release factor 1 Mmwyl1_3599 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 152997676 Common - Adenosylcobinamide-phosphate guanylyltransferase Mmwyl1_3675 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 152994423 Nonpathogen - hypothetical protein Mmwyl1_0385 2 None None None 152996264 Common - hypothetical protein Mmwyl1_2242 5 None None None 152997024 Common - cation transporter Mmwyl1_3013 131 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 152995994 Common - alanine dehydrogenase/PNT domain protein Mmwyl1_1970 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 152994541 Common - sigma54 specific transcriptional regulator, Fis family Mmwyl1_0505 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 152994549 Nonpathogen - hypothetical protein Mmwyl1_0513 5 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152998475 Common - TrkA-N domain protein Mmwyl1_4480 108 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 152994957 Common - transcriptional regulator, GntR family Mmwyl1_0926 140 COG1802 GntR, Transcriptional regulators Transcription 152997758 Common - peptidase M24 Mmwyl1_3757 231 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 152994964 Common - glycyl-tRNA synthetase Mmwyl1_0933 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 152995365 Common - transcriptional regulator, TetR family Mmwyl1_1336 87 COG1309 AcrR, Transcriptional regulator Transcription 152995661 Common - AMP-dependent synthetase and ligase Mmwyl1_1634 210 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152997306 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3301 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996924 Common - apolipoprotein N-acyltransferase Mmwyl1_2913 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 152994228 Common - Inositol-phosphate phosphatase Mmwyl1_0186 208 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 152997629 Common - aspartate kinase Mmwyl1_3627 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 152997778 Common - transcription elongation factor GreB Mmwyl1_3777 191 COG0782 GreA, Transcription elongation factor Transcription 152994272 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0230 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152994585 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mmwyl1_0549 120 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 152994461 Common - transcriptional coactivator/pterin dehydratase Mmwyl1_0423 106 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 152996988 Common - GCN5-related N-acetyltransferase Mmwyl1_2977 85 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 152994854 Common - UDP-glucose/GDP-mannose dehydrogenase Mmwyl1_0821 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 152994316 Common - hypothetical protein Mmwyl1_0275 6 None None None 152996626 Common - UDP-N-acetylmuramate--alanine ligase Mmwyl1_2613 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 152995481 Common - Excinuclease ABC C subunit domain protein Mmwyl1_1452 70 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 152997605 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Mmwyl1_3603 190 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 152998438 Nonpathogen - hypothetical protein Mmwyl1_4443 2 None None None 152994405 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mmwyl1_0367 161 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 152994941 Common - putative transcriptional regulator, GntR family Mmwyl1_0910 200 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152994963 Common - hypothetical protein Mmwyl1_0932 5 None None None 152995609 Nonpathogen - hypothetical protein Mmwyl1_1581 1 None None None 152995637 Common - isochorismatase hydrolase Mmwyl1_1609 71 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 152996677 Common - transcriptional regulator, AraC family Mmwyl1_2664 114 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152995995 Common - aldehyde dehydrogenase Mmwyl1_1971 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152998321 Common - protein of unknown function DUF214 Mmwyl1_4326 110 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 152996488 Nonpathogen - glycosyl transferase group 1 Mmwyl1_2466 13 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152994558 Common - protein of unknown function DUF81 Mmwyl1_0522 10 COG0730 COG0730, Predicted permeases General function prediction only 152995846 Common - Extracellular ligand-binding receptor Mmwyl1_1822 133 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 152995440 Common - Phosphoglycerate mutase Mmwyl1_1411 95 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 152997490 Common - MATE efflux family protein Mmwyl1_3487 153 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 152994274 Common - extracellular solute-binding protein family 1 Mmwyl1_0232 65 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996358 Common - histidine triad (HIT) protein Mmwyl1_2336 65 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 152995750 Common - ATP-dependent Clp protease, ATP-binding subunit ClpX Mmwyl1_1724 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 152994690 Common - Cupin 2 conserved barrel domain protein Mmwyl1_0656 15 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 152994841 Common - Coenzyme F390 synthetase-like protein Mmwyl1_0807 22 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 152997136 Common - periplasmic glucan biosynthesis protein MdoG Mmwyl1_3126 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 152995148 Nonpathogen - hypothetical protein Mmwyl1_1117 1 None None None 152996143 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Mmwyl1_2121 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 152997461 Common - K+-dependent Na+/Ca+ exchanger related-protein Mmwyl1_3458 155 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 152997602 Common - Glutamyl-tRNA reductase Mmwyl1_3600 181 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 152995992 Common - NAD(P)(+) transhydrogenase (AB-specific) Mmwyl1_1968 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 152997185 Common - 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit Mmwyl1_3177 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152997205 Common - Amidase Mmwyl1_3197 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152998175 Common - protein of unknown function DUF35 Mmwyl1_4179 37 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 152995347 Nonpathogen - hypothetical protein Mmwyl1_1318 4 None None None 152994759 Common - carboxyl-terminal protease Mmwyl1_0725 185 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 152998454 Common - UBA/THIF-type NAD/FAD binding protein Mmwyl1_4459 222 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 152998388 Common - extracellular solute-binding protein family 3 Mmwyl1_4393 116 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152994798 Common - protein of unknown function DUF423 Mmwyl1_0764 34 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 152995135 Common - acetylornithine deacetylase (ArgE) Mmwyl1_1104 206 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152995967 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mmwyl1_1943 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 152995548 Common - transcriptional regulator, XRE family Mmwyl1_1520 78 COG1396 HipB, Predicted transcriptional regulators Transcription 152997883 Common - Beta-ketoacyl synthase Mmwyl1_3885 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152996071 Common - O-succinylhomoserine sulfhydrylase Mmwyl1_2049 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 152994805 Common - UDP-N-acetylglucosamine pyrophosphorylase Mmwyl1_0771 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 152997215 Common - amidase, hydantoinase/carbamoylase family Mmwyl1_3207 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152998464 Common - ATP synthase I chain Mmwyl1_4469 12 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 152996090 Common - GCN5-related N-acetyltransferase Mmwyl1_2068 50 COG3153 COG3153, Predicted acetyltransferase General function prediction only 152994514 Common - Ethanolamine ammonia lyase large subunit Mmwyl1_0477 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 152998017 Nonpathogen - plasmid stabilization system Mmwyl1_4021 11 None None None 152996477 Common - 2,4-diaminobutyrate 4-transaminase Mmwyl1_2455 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 152996195 Common - ABC transporter related Mmwyl1_2173 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 152996296 Common - formate dehydrogenase, alpha subunit Mmwyl1_2274 214 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 152997399 Common - PHP domain protein Mmwyl1_3396 125 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 152996629 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Mmwyl1_2616 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 152995080 Common - bis(5'nucleosyl)-tetraphosphatase, ApaH Mmwyl1_1049 99 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 152997606 Common - ribose-phosphate pyrophosphokinase Mmwyl1_3604 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 152995922 Common - diguanylate cyclase Mmwyl1_1898 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152997049 Common - beta-lactamase domain protein Mmwyl1_3038 27 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 152996765 Common - D-lactate dehydrogenase Mmwyl1_2752 64 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 152994599 Common - hypothetical protein Mmwyl1_0564 11 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 152998467 Common - methyltransferase GidB Mmwyl1_4472 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 152996533 Common - transaldolase Mmwyl1_2514 185 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 152995334 Common - protein-L-isoaspartate O-methyltransferase Mmwyl1_1305 154 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 152997468 Common - ribosomal protein S6 Mmwyl1_3465 197 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 152997626 Nonpathogen - sodium pump decarboxylase, gamma subunit Mmwyl1_3624 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 152998473 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4478 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 152996791 Common - mannonate dehydratase Mmwyl1_2778 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 152995566 Common - aminotransferase class-III Mmwyl1_1538 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 152995930 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_1906 203 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152994318 Common - transposase IS116/IS110/IS902 family protein Mmwyl1_0277 15 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 152995599 Common - acyl-CoA dehydrogenase domain protein Mmwyl1_1571 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 152996683 Common - aromatic-ring-hydroxylating dioxygenase beta subunit Mmwyl1_2670 14 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 152997411 Common - cytochrome C biogenesis protein Mmwyl1_3408 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 152995670 Common - PAS/PAC sensor hybrid histidine kinase Mmwyl1_1644 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996153 Common - malonyl CoA-acyl carrier protein transacylase Mmwyl1_2131 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 152996263 Common - signal peptide peptidase SppA, 36K type Mmwyl1_2241 173 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 152995858 Common - aldehyde dehydrogenase Mmwyl1_1834 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994359 Common - transferase hexapeptide repeat Mmwyl1_0319 195 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 152994856 Common - WbbJ protein Mmwyl1_0823 195 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 152996657 Common - protein-export membrane protein SecF Mmwyl1_2644 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 152995491 Common - glycogen debranching enzyme GlgX Mmwyl1_1462 134 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 152994224 Common - extracellular solute-binding protein family 1 Mmwyl1_0182 24 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 152996822 Common - hypothetical protein Mmwyl1_2810 16 None None None 152996422 Common - ribosomal protein L13 Mmwyl1_2400 235 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 152996341 Common - histidine kinase Mmwyl1_2319 96 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152994283 Common - cytochrome B561 Mmwyl1_0241 45 COG3038 CybB, Cytochrome B561 Energy production and conversion 152995550 Nonpathogen - branched-chain amino acid transport Mmwyl1_1522 3 None None None 152994672 Common - rare lipoprotein A Mmwyl1_0638 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 152997900 Common - formiminoglutamate deiminase Mmwyl1_3903 127 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 152994211 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0169 154 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 152995828 Common - ABC-type Fe3+ transport system, periplasmic component Mmwyl1_1804 33 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152994350 Common - type II secretion system protein E Mmwyl1_0309 226 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 152996554 Common - Rhodanese domain protein Mmwyl1_2535 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 152994982 Common - ABC transporter related Mmwyl1_0951 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 152995470 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_1441 16 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152997099 Common - hypothetical protein Mmwyl1_3089 6 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152994832 Common - putative transcriptional regulator, AsnC family Mmwyl1_0798 17 COG1522 Lrp, Transcriptional regulators Transcription 152994061 Common - DNA protecting protein DprA Mmwyl1_0018 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 152995216 Nonpathogen - hypothetical protein Mmwyl1_1187 1 None None None 152997981 Common - cation antiporter Mmwyl1_3985 84 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 152996920 Common - tRNA-i(6)A37 thiotransferase enzyme MiaB Mmwyl1_2909 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 152995519 Common - hypothetical protein Mmwyl1_1490 3 None None None 152998229 Common - diacylglycerol kinase Mmwyl1_4234 84 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 152996647 Common - DNA mismatch repair protein MutL Mmwyl1_2634 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 152994466 Nonpathogen - hypothetical protein Mmwyl1_0428 1 None None None 152995498 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_1469 126 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152998220 Common - protein of unknown function DUF227 Mmwyl1_4225 9 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 152996366 Common - HesB/YadR/YfhF-family protein Mmwyl1_2344 70 COG0316 IscA, Uncharacterized conserved protein Function unknown 152997817 Common - peptidase dimerisation domain protein Mmwyl1_3818 127 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 152998115 Nonpathogen - hypothetical protein Mmwyl1_4119 1 None None None 152995311 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Mmwyl1_1282 182 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 152995089 Common - phosphoglycolate phosphatase Mmwyl1_1058 195 COG0546 Gph, Predicted phosphatases General function prediction only 152996359 Common - SMP-30/Gluconolaconase/LRE domain protein Mmwyl1_2337 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 152994773 Common - D-tyrosyl-tRNA(Tyr) deacylase Mmwyl1_0739 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 152995618 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1590 49 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152994313 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0271 23 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152996134 Common - hypothetical protein Mmwyl1_2112 2 None None None 152996534 Common - transferase hexapeptide repeat containing protein Mmwyl1_2515 135 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 152994068 Common - extracellular solute-binding protein family 1 Mmwyl1_0025 109 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996009 Common - ABC transporter related Mmwyl1_1986 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152994607 Common - uncharacterized phage Mu protein GP47-like protein Mmwyl1_0572 11 None None None 152996725 Common - Alpha-N-arabinofuranosidase Mmwyl1_2712 31 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 152996098 Common - RNA methyltransferase, TrmH family, group 1 Mmwyl1_2076 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 152996977 Nonpathogen - alpha/beta hydrolase Mmwyl1_2966 4 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152997255 Nonpathogen - hypothetical protein Mmwyl1_3249 1 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 152996372 Common - aldo/keto reductase Mmwyl1_2350 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 152996541 Common - Methyltransferase type 11 Mmwyl1_2522 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152997683 Common - hypothetical protein Mmwyl1_3682 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 152995580 Nonpathogen - hypothetical protein Mmwyl1_1552 1 None None None 152995128 Common - L-aspartate oxidase Mmwyl1_1097 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 152995351 Common - protein of unknown function DUF6 transmembrane Mmwyl1_1322 103 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152995358 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Mmwyl1_1329 148 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 152997148 Common - Cupin 2 conserved barrel domain protein Mmwyl1_3139 15 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 152997305 Common - putative CheW protein Mmwyl1_3300 124 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 152996178 Common - glutamate racemase Mmwyl1_2156 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 152998371 Common - HipA domain protein Mmwyl1_4376 55 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 152994709 Common - two component transcriptional regulator, winged helix family Mmwyl1_0675 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152995684 Common - transcriptional regulator, LysR family Mmwyl1_1658 176 COG0583 LysR, Transcriptional regulator Transcription 152994989 Common - Urease accessory protein UreF Mmwyl1_0958 76 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 152997891 Common - transcriptional regulator, LysR family Mmwyl1_3893 162 COG0583 LysR, Transcriptional regulator Transcription 152994197 Common - transferase hexapeptide repeat containing protein Mmwyl1_0155 162 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 152995957 Common - response regulator receiver modulated diguanylate cyclase Mmwyl1_1933 208 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152995851 Common - aromatic-ring-hydroxylating dioxygenase beta subunit Mmwyl1_1827 12 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 152997703 Common - hypothetical protein Mmwyl1_3702 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 152996310 Common - diguanylate cyclase Mmwyl1_2288 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152995715 Nonpathogen - hypothetical protein Mmwyl1_1689 1 None None None 152996227 Common - pseudouridine synthase Mmwyl1_2205 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 152994914 Common - extracellular solute-binding protein family 1 Mmwyl1_0882 60 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152994682 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0648 144 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152997016 Common - two component transcriptional regulator, LuxR family Mmwyl1_3005 175 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997968 Common - sodium:neurotransmitter symporter Mmwyl1_3971 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 152996603 Common - hypothetical protein Mmwyl1_2590 8 None None None 152994539 Common - cyclic nucleotide-binding protein Mmwyl1_0503 33 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 152996239 Nonpathogen - hypothetical protein Mmwyl1_2217 1 None None None 152996220 Common - hypothetical protein Mmwyl1_2198 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 152996323 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2301 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997128 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_3118 100 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152995468 Common - Na+ symporter Mmwyl1_1439 171 COG4147 DhlC, Predicted symporter General function prediction only 152997384 Common - PAS/PAC sensor hybrid histidine kinase Mmwyl1_3381 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996216 Common - Tol-Pal system beta propeller repeat TolB Mmwyl1_2194 156 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 152998268 Common - ribosomal protein L2 Mmwyl1_4273 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 152997318 Nonpathogen - hypothetical protein Mmwyl1_3313 1 None None None 152997729 Common - formate/nitrite transporter Mmwyl1_3728 91 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 152998317 Common - type I secretion outer membrane protein, TolC family Mmwyl1_4322 135 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152995838 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_1814 69 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152995480 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_1451 83 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152998448 Common - transcriptional regulator, LysR family Mmwyl1_4453 181 COG0583 LysR, Transcriptional regulator Transcription 152995316 Common - DNA polymerase III, alpha subunit Mmwyl1_1287 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 152997448 Common - flagellar protein export ATPase FliI Mmwyl1_3445 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 152995730 Common - Ribonuclease H Mmwyl1_1704 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 152995201 Common - dienelactone hydrolase-like protein Mmwyl1_1172 9 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 152995153 Common - periplasmic solute binding protein Mmwyl1_1122 160 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 152996165 Common - dihydrodipicolinate synthase Mmwyl1_2143 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 152996739 Common - Membrane dipeptidase Mmwyl1_2726 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 152997837 Common - diguanylate cyclase Mmwyl1_3838 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152995891 Common - Monosaccharide-transporting ATPase Mmwyl1_1867 129 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 152995238 Common - ImcF domain protein Mmwyl1_1209 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 152997783 Common - Carboxylesterase Mmwyl1_3782 95 COG0400 COG0400, Predicted esterase General function prediction only 152998183 Common - ABC transporter related Mmwyl1_4187 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152996400 Common - DEAD/DEAH box helicase domain protein Mmwyl1_2378 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152997277 Common - aldehyde dehydrogenase Mmwyl1_3272 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152995577 Common - Integrase catalytic region Mmwyl1_1549 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152998401 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4406 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152996241 Common - domain of unknown function DUF1731 Mmwyl1_2219 111 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 152997822 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3823 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152997068 Nonpathogen - hypothetical protein Mmwyl1_3058 1 None None None 152996317 Common - hypothetical protein Mmwyl1_2295 13 None None None 152996705 Common - CRISPR-associated protein, Crm2 family Mmwyl1_2692 23 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 152995679 Common - ATPase BadF/BadG/BcrA/BcrD type Mmwyl1_1653 61 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 152997014 Common - Prephenate dehydratase Mmwyl1_3003 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 152994962 Common - putative thiol-disulphide oxidoreductase DCC Mmwyl1_0931 17 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 152998129 Common - Asparaginase Mmwyl1_4133 123 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 152995271 Common - glucose-1-phosphate adenylyltransferase Mmwyl1_1242 195 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 152997993 Common - ABC transporter related Mmwyl1_3997 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 152994324 Common - diguanylate cyclase Mmwyl1_0283 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996000 Common - ornithine carbamoyltransferase Mmwyl1_1976 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 152994925 Common - protein of unknown function DUF88 Mmwyl1_0893 44 COG1432 COG1432, Uncharacterized conserved protein Function unknown 152998262 Common - ribosomal protein S17 Mmwyl1_4267 233 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 152996840 Common - protein of unknown function DUF1244 Mmwyl1_2828 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 152996880 Common - protein of unknown function DUF28 Mmwyl1_2868 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 152996730 Common - Aldose 1-epimerase Mmwyl1_2717 91 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 152997230 Common - Inorganic diphosphatase Mmwyl1_3224 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 152998410 Common - phosphate ABC transporter, inner membrane subunit PstA Mmwyl1_4415 225 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 152994285 Common - transcriptional regulator, LysR family Mmwyl1_0243 163 COG0583 LysR, Transcriptional regulator Transcription 152996252 Common - PP-loop domain protein Mmwyl1_2230 164 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 152997364 Nonpathogen - hypothetical protein Mmwyl1_3360 2 None None None 152996759 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mmwyl1_2746 44 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 152997799 Common - hypothetical protein Mmwyl1_3800 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 152997792 Common - L-threonine 3-dehydrogenase Mmwyl1_3793 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 152994897 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0865 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152996895 Common - type I secretion outer membrane protein, TolC family Mmwyl1_2883 145 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152998441 Common - hypothetical protein Mmwyl1_4446 31 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 152996808 Common - succinyl-CoA synthetase, alpha subunit Mmwyl1_2796 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 152995115 Common - uracil-DNA glycosylase Mmwyl1_1084 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 152994202 Nonpathogen - hypothetical protein Mmwyl1_0160 1 None None None 152994173 Common - protein of unknown function DUF81 Mmwyl1_0131 137 COG0730 COG0730, Predicted permeases General function prediction only 152995000 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0969 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995208 Common - Malate synthase Mmwyl1_1179 76 COG2225 AceB, Malate synthase Energy production and conversion 152995187 Common - L-2,4-diaminobutyric acid acetyltransferase Mmwyl1_1158 29 COG0456 RimI, Acetyltransferases General function prediction only 152994702 Common - protein of unknown function DUF218 Mmwyl1_0668 59 COG1434 COG1434, Uncharacterized conserved protein Function unknown 152997716 Common - NAD(P)H dehydrogenase (quinone) Mmwyl1_3715 85 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 152995103 Common - protein of unknown function UPF0057 Mmwyl1_1072 38 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 152998026 Common - glucose-methanol-choline oxidoreductase Mmwyl1_4030 91 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 152998234 Common - Polyprenyl synthetase Mmwyl1_4239 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 152996437 Common - protein of unknown function DUF1239 Mmwyl1_2415 3 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 152995771 Nonpathogen - hypothetical protein Mmwyl1_1745 1 None None None 152995521 Nonpathogen - hypothetical protein Mmwyl1_1492 1 None None None 152997219 Common - inner-membrane translocator Mmwyl1_3211 147 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 152995489 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1460 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996847 Common - bacterioferritin Mmwyl1_2835 102 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 152998108 Common - hypothetical protein Mmwyl1_4112 7 None None None 152995662 Common - ABC transporter related Mmwyl1_1635 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152998428 Common - Uncharacterized protein UPF0065 Mmwyl1_4433 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152997007 Common - ribonucleoside-diphosphate reductase, alpha subunit Mmwyl1_2996 202 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 152994891 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0859 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152995510 Common - 5'-nucleotidase, lipoprotein e(P4) family Mmwyl1_1481 30 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 152997483 Common - glycosyl transferase family 2 Mmwyl1_3480 132 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 152996112 Common - transcriptional regulator, LysR family Mmwyl1_2090 193 COG0583 LysR, Transcriptional regulator Transcription 152997079 Common - FAD dependent oxidoreductase Mmwyl1_3069 97 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152995045 Common - two component transcriptional regulator, winged helix family Mmwyl1_1014 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152994973 Common - glutathione-dependent formaldehyde-activating GFA Mmwyl1_0942 49 COG3791 COG3791, Uncharacterized conserved protein Function unknown 152995265 Common - OmpW family protein Mmwyl1_1236 70 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 152994184 Common - major facilitator superfamily MFS_1 Mmwyl1_0142 3 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996858 Common - lytic murein transglycosylase B Mmwyl1_2846 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 152998004 Common - permease YjgP/YjgQ family protein Mmwyl1_4008 77 COG0795 COG0795, Predicted permeases General function prediction only 152998190 Common - ATP-dependent helicase HrpB Mmwyl1_4194 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 152997488 Common - Rhodanese domain protein Mmwyl1_3485 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 152995796 Common - periplasmic binding protein Mmwyl1_1770 37 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 152995602 Common - hypothetical protein Mmwyl1_1574 13 None None None 152996585 Common - amino acid adenylation domain Mmwyl1_2568 198 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152995607 Common - acetyl-CoA C-acyltransferase FadA Mmwyl1_1579 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152998163 Common - Flavin-containing monooxygenase Mmwyl1_4167 98 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 152996751 Common - homogentisate 1,2-dioxygenase Mmwyl1_2738 49 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 152997425 Common - OmpA/MotB domain protein Mmwyl1_3422 59 COG1360 MotB, Flagellar motor protein Cell motility and secretion 152996700 Nonpathogen - hypothetical protein Mmwyl1_2687 1 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 152997667 Common - transcriptional regulator, LysR family Mmwyl1_3666 140 COG0583 LysR, Transcriptional regulator Transcription 152994909 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0877 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994473 Common - GCN5-related N-acetyltransferase Mmwyl1_0436 59 COG0456 RimI, Acetyltransferases General function prediction only 152995476 Common - acriflavin resistance protein Mmwyl1_1447 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 152994627 Nonpathogen - hypothetical protein Mmwyl1_0593 1 None None None 152996558 Common - hypothetical protein Mmwyl1_2539 28 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 152997859 Common - HAD superfamily (subfamily IIIB) phosphatase, TIGR01672 Mmwyl1_3860 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 152998144 Common - inosine-5'-monophosphate dehydrogenase Mmwyl1_4148 237 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 152997481 Common - lipopolysaccharide heptosyltransferase II Mmwyl1_3478 93 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 152994662 Common - HipA domain protein Mmwyl1_0628 62 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 152995327 Common - CTP synthase Mmwyl1_1298 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 152994086 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_0043 111 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996752 Common - transcriptional regulator, MarR family Mmwyl1_2739 40 COG1846 MarR, Transcriptional regulators Transcription 152997592 Common - argininosuccinate lyase Mmwyl1_3590 231 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 152997346 Common - two component transcriptional regulator, LytTR family Mmwyl1_3341 210 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 152994883 Common - ABC transporter related Mmwyl1_0851 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 152998044 Common - hypothetical protein Mmwyl1_4048 12 None None None 152995320 Common - secretion protein HlyD family protein Mmwyl1_1291 160 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 152996660 Common - queuine tRNA-ribosyltransferase Mmwyl1_2647 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 152997737 Common - diguanylate phosphodiesterase Mmwyl1_3736 63 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 152997637 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3635 14 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997056 Common - Transcriptional regulator IclR Mmwyl1_3045 111 COG1414 IclR, Transcriptional regulator Transcription 152997521 Common - FAD dependent oxidoreductase Mmwyl1_3518 126 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152994419 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Mmwyl1_0381 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 152997193 Common - UspA domain protein Mmwyl1_3185 58 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 152995775 Common - hypothetical protein Mmwyl1_1749 10 None None None 152994073 Common - transcriptional regulator, TetR family Mmwyl1_0030 89 COG1309 AcrR, Transcriptional regulator Transcription 152998132 Common - ribose 5-phosphate isomerase Mmwyl1_4136 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 152995569 Common - electron transport complex, RnfABCDGE type, G subunit Mmwyl1_1541 59 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 152994238 Common - diguanylate cyclase Mmwyl1_0196 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152997412 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Mmwyl1_3409 132 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 152995278 Common - holo-acyl-carrier-protein synthase Mmwyl1_1249 153 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 152995258 Common - MgtC/SapB transporter Mmwyl1_1229 117 COG1285 SapB, Uncharacterized membrane protein Function unknown 152996881 Common - putative transcriptional regulator, GntR family Mmwyl1_2869 227 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152995706 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_1680 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152994725 Common - transport system permease protein Mmwyl1_0691 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152997850 Nonpathogen - hypothetical protein Mmwyl1_3851 3 None None None 152998310 Common - LuxP protein precursor Mmwyl1_4315 4 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152995424 Common - hypothetical protein Mmwyl1_1395 8 None None None 152998232 Common - ribosomal protein L27 Mmwyl1_4237 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 152996128 Common - GCN5-related N-acetyltransferase Mmwyl1_2106 27 COG0456 RimI, Acetyltransferases General function prediction only 152995594 Common - Xanthine/uracil/vitamin C permease Mmwyl1_1566 134 COG2252 COG2252, Permeases General function prediction only 152998076 Common - betaine aldehyde dehydrogenase Mmwyl1_4080 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994490 Common - protein of unknown function DUF81 Mmwyl1_0453 121 COG0730 COG0730, Predicted permeases General function prediction only 152997579 Common - flagellar L-ring protein Mmwyl1_3577 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 152994944 Common - lysyl-tRNA synthetase-related protein GenX Mmwyl1_0913 218 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 152994259 Common - NADH:flavin oxidoreductase/NADH oxidase Mmwyl1_0217 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 152995500 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_1471 106 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996856 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mmwyl1_2844 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 152997785 Common - DNA-directed DNA polymerase Mmwyl1_3784 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 152998212 Common - helix-turn-helix domain protein Mmwyl1_4217 33 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 152995793 Common - drug resistance transporter, Bcr/CflA subfamily Mmwyl1_1767 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152995818 Common - hypothetical protein Mmwyl1_1794 2 None None None 152995094 Common - Indole-3-glycerol-phosphate synthase Mmwyl1_1063 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 152997868 Common - peptide methionine sulfoxide reductase Mmwyl1_3869 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 152994800 Common - histone family protein nucleoid-structuring protein H-NS Mmwyl1_0766 3 COG2916 Hns, DNA-binding protein H-NS General function prediction only 152995410 Common - carboxynorspermidine decarboxylase Mmwyl1_1381 53 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 152996240 Common - DNA topoisomerase type IA zn finger domain protein Mmwyl1_2218 95 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 152997158 Common - cyclase family protein Mmwyl1_3149 57 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 152997553 Common - hypothetical protein Mmwyl1_3551 14 None None None 152997108 Common - phenylacetic acid degradation protein PaaD Mmwyl1_3098 62 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 152994213 Common - beta-lactamase domain protein Mmwyl1_0171 82 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 152997723 Common - hypothetical protein Mmwyl1_3722 45 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 152997621 Common - porin Gram-negative type Mmwyl1_3619 32 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 152995164 Nonpathogen - hypothetical protein Mmwyl1_1135 4 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 152996027 Common - major facilitator superfamily MFS_1 Mmwyl1_2005 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996397 Common - protein of unknown function DUF599 Mmwyl1_2375 25 COG3821 COG3821, Predicted membrane protein Function unknown 152997925 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3928 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994568 Common - hypothetical protein Mmwyl1_0532 2 None None None 152997022 Common - peptidase M23B Mmwyl1_3011 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 152994513 Common - Ethanolamine ammonia-lyase Mmwyl1_0476 54 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 152998140 Common - major facilitator superfamily MFS_1 Mmwyl1_4144 151 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152995027 Common - efflux transporter, RND family, MFP subunit Mmwyl1_0996 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152997004 Common - pyridoxamine 5'-phosphate oxidase Mmwyl1_2993 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 152997741 Common - protein of unknown function UPF0047 Mmwyl1_3740 123 COG0432 COG0432, Uncharacterized conserved protein Function unknown 152995075 Common - ribosomal protein S21 Mmwyl1_1044 102 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 152994651 Common - Aldose 1-epimerase Mmwyl1_0617 53 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 152995665 Common - condensation domain protein Mmwyl1_1638 65 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152998279 Common - ribosomal protein L7/L12 Mmwyl1_4284 212 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 152994052 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0009 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996280 Common - protein of unknown function DUF188 Mmwyl1_2258 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 152995685 Common - methionine aminopeptidase, type I Mmwyl1_1659 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 152996940 Common - alpha/beta hydrolase fold Mmwyl1_2929 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152996321 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_2299 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152996339 Common - protein of unknown function DUF329 Mmwyl1_2317 69 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 152995629 Common - thioesterase superfamily protein Mmwyl1_1601 39 COG0824 FcbC, Predicted thioesterase General function prediction only 152996520 Common - peptidylprolyl isomerase FKBP-type Mmwyl1_2501 158 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 152994448 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0410 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995553 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mmwyl1_1525 130 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 152996926 Common - leucyl-tRNA synthetase Mmwyl1_2915 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152994625 Common - hypothetical protein Mmwyl1_0590 6 None None None 152996022 Common - glutathione-dependent formaldehyde-activating GFA Mmwyl1_2000 60 COG3791 COG3791, Uncharacterized conserved protein Function unknown 152997708 Common - PfkB domain protein Mmwyl1_3707 195 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 152994127 Common - transcriptional regulator, LysR family Mmwyl1_0085 87 COG0583 LysR, Transcriptional regulator Transcription 152998406 Common - Hpt domain protein Mmwyl1_4411 4 None None None 152997297 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Mmwyl1_3292 20 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 152997226 Common - orotidine 5'-phosphate decarboxylase Mmwyl1_3220 166 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 152997348 Common - protein of unknown function DUF181 Mmwyl1_3343 51 COG1944 COG1944, Uncharacterized conserved protein Function unknown 152994142 Common - rRNA (guanine-N(2)-)-methyltransferase Mmwyl1_0100 89 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 152998091 Common - transcriptional regulator, GntR family Mmwyl1_4095 120 COG1802 GntR, Transcriptional regulators Transcription 152994532 Common - succinic semialdehyde dehydrogenase Mmwyl1_0496 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996819 Common - hypothetical protein Mmwyl1_2807 20 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 152996749 Common - maleylacetoacetate isomerase Mmwyl1_2736 86 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152995069 Common - glucose-6-phosphate 1-dehydrogenase Mmwyl1_1038 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 152997436 Common - flagellar biosynthetic protein FliQ Mmwyl1_3433 125 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 152998210 Nonpathogen - hypothetical protein Mmwyl1_4215 4 None None None 152995545 Common - hypothetical protein Mmwyl1_1517 4 None None None 152998373 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_4378 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995764 Common - Dihydroorotate oxidase Mmwyl1_1738 235 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 152996963 Nonpathogen - hypothetical protein Mmwyl1_2952 1 None None None 152995206 Common - hypothetical protein Mmwyl1_1177 4 None None None 152995426 Common - 3'-5' exonuclease Mmwyl1_1397 15 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 152998037 Common dddD L-carnitine dehydratase/bile acid-inducible protein F Mmwyl1_4041 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 152997228 Nonpathogen - hypothetical protein Mmwyl1_3222 6 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 152995949 Common - inner-membrane translocator Mmwyl1_1925 108 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 152994540 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0504 191 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152997085 Common - FAD dependent oxidoreductase Mmwyl1_3075 125 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152995735 Common - transcription-repair coupling factor Mmwyl1_1709 234 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 152995170 Common - small multidrug resistance protein Mmwyl1_1141 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 152995872 Common - hypothetical protein Mmwyl1_1848 10 None None None 152996462 Common - ABC transporter related Mmwyl1_2440 249 COG4136 COG4136, ABC-type uncharacterized transport system, ATPase component General function prediction only 152996182 Common - spermine synthase Mmwyl1_2160 33 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 152997547 Common - CRISPR-associated protein Cas5 family Mmwyl1_3544 27 None None None 152994162 Common - extracellular solute-binding protein family 1 Mmwyl1_0120 89 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152996552 Common - conserved hypothetical protein 103 Mmwyl1_2533 191 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 152997956 Common - hypothetical protein Mmwyl1_3959 9 None None None 152996444 Common - protein of unknown function DUF615 Mmwyl1_2422 58 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 152994231 Common - Oligogalacturonate-specific porin Mmwyl1_0189 9 None None None 152997759 Common - protein of unknown function UPF0149 Mmwyl1_3758 39 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 152996578 Common - periplasmic lipoprotein-like protein Mmwyl1_2559 22 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 152996985 Common - hypothetical protein Mmwyl1_2974 2 None None None 152997250 Nonpathogen - hypothetical protein Mmwyl1_3244 1 None None None 152998067 Common - protein of unknown function DUF1365 Mmwyl1_4071 63 COG3496 COG3496, Uncharacterized conserved protein Function unknown 152997846 Common - ABC transporter related Mmwyl1_3847 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 152996504 Common - protein of unknown function DUF1330 Mmwyl1_2483 44 COG5470 COG5470, Uncharacterized conserved protein Function unknown 152998306 Common - tRNA (uracil-5-)-methyltransferase Mmwyl1_4311 172 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 152997564 Common - acylneuraminate cytidylyltransferase Mmwyl1_3562 94 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 152997508 Common - 6-phosphogluconate dehydrogenase, decarboxylating Mmwyl1_3505 169 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 152997877 Common - AMP-dependent synthetase and ligase Mmwyl1_3878 55 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 152995929 Common - fumarate lyase Mmwyl1_1905 234 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 152995022 Common - Salicylate 1-monooxygenase Mmwyl1_0991 91 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152997322 Common - protein of unknown function DUF1460 Mmwyl1_3317 17 None None None 152994529 Common - GCN5-related N-acetyltransferase Mmwyl1_0493 123 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 152997212 Common - hypothetical protein Mmwyl1_3204 6 None None None 152997936 Common - Extradiol ring-cleavage dioxygenase LigAB LigA subunit Mmwyl1_3939 17 None None None 152998446 Common - Fe-S metabolism associated SufE Mmwyl1_4451 91 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 152998248 Common - ribosomal protein S11 Mmwyl1_4253 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 152997560 Common - NUDIX hydrolase Mmwyl1_3558 119 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 152994684 Common - sulfate ABC transporter, inner membrane subunit CysW Mmwyl1_0650 208 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 152995386 Common - histidyl-tRNA synthetase Mmwyl1_1357 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152995959 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Mmwyl1_1935 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152996118 Common - sigma 54 modulation protein/ribosomal protein S30EA Mmwyl1_2096 51 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 152994357 Common - hypothetical protein Mmwyl1_0317 8 None None None 152996863 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Mmwyl1_2851 168 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 152994641 Common - ABC transporter related Mmwyl1_0607 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152994130 Nonpathogen - hypothetical protein Mmwyl1_0088 1 None None None 152996010 Common - Monosaccharide-transporting ATPase Mmwyl1_1987 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 152997420 Common - hypothetical protein Mmwyl1_3417 104 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 152996932 Common - cyclic nucleotide-binding protein Mmwyl1_2921 13 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 152995415 Common - major facilitator superfamily MFS_1 Mmwyl1_1386 80 None None None 152995385 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Mmwyl1_1356 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 152995978 Common - ATP synthase F1, beta subunit Mmwyl1_1954 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 152995985 Common - ATP synthase F1, alpha subunit Mmwyl1_1961 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 152996860 Common - Peptidoglycan glycosyltransferase Mmwyl1_2848 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 152994341 Common - hypothetical protein Mmwyl1_0300 36 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152995364 Common - protein of unknown function DUF6 transmembrane Mmwyl1_1335 95 COG2962 RarD, Predicted permeases General function prediction only 152994814 Common - Cupin 2 conserved barrel domain protein Mmwyl1_0780 41 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 152996949 Common - pseudouridine synthase Mmwyl1_2938 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 152998240 Common - Peptidase M16C associated domain protein Mmwyl1_4245 106 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 152998336 Common - alpha amylase catalytic region Mmwyl1_4341 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 152994060 Common - peptide deformylase Mmwyl1_0017 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 152995056 Common - protein of unknown function DUF150 Mmwyl1_1025 184 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 152997163 Common - putative transcriptional regulator, GntR family Mmwyl1_3154 222 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152996939 Common - sodium/hydrogen exchanger Mmwyl1_2928 123 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 152998040 Common dddC methylmalonate-semialdehyde dehydrogenase Mmwyl1_4044 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152995346 Common - putative iron-sulfur cluster binding protein Mmwyl1_1317 139 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 152994420 Common - Endoribonuclease L-PSP Mmwyl1_0382 43 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152996415 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Mmwyl1_2393 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 152994371 Common - transcriptional regulator, LysR family Mmwyl1_0333 152 COG0583 LysR, Transcriptional regulator Transcription 152995402 Nonpathogen - hypothetical protein Mmwyl1_1373 1 COG3895 COG3895, Predicted periplasmic protein General function prediction only 152996781 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_2768 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152997333 Common - putative undecaprenol kinase Mmwyl1_3328 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 152995907 Common - response regulator receiver protein Mmwyl1_1883 33 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997327 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3322 118 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994261 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0219 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994571 Common - transcriptional regulator, LysR family Mmwyl1_0535 191 COG0583 LysR, Transcriptional regulator Transcription 152994295 Common - ABC transporter related Mmwyl1_0253 247 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152995718 Common - luciferase family protein Mmwyl1_1692 108 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 152998323 Common - signal recognition particle-docking protein FtsY Mmwyl1_4328 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 152995900 Common - xylose isomerase Mmwyl1_1876 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 152996609 Common - translation initiation factor IF-3 Mmwyl1_2596 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 152994256 Common - glycoside hydrolase family 3 domain protein Mmwyl1_0214 111 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 152997336 Common - hypothetical protein Mmwyl1_3331 18 None None None 152997471 Common - protein of unknown function DUF6 transmembrane Mmwyl1_3468 186 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152995294 Nonpathogen - hypothetical protein Mmwyl1_1265 1 None None None 152996512 Common - plasmid maintenance system killer Mmwyl1_2492 2 None None None 152995862 Common - FAD dependent oxidoreductase Mmwyl1_1838 96 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152998130 Common - arginyl-tRNA synthetase Mmwyl1_4134 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152996694 Common - hypothetical protein Mmwyl1_2681 4 None None None 152994047 Common - DNA gyrase, B subunit Mmwyl1_0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 152994491 Common - aminotransferase class V Mmwyl1_0454 164 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 152996086 Common - periplasmic binding protein Mmwyl1_2064 68 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 152997715 Common - Licheninase Mmwyl1_3714 13 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 152994226 Common - metal-dependent hydrolase of the beta-lactamase superfamily III Mmwyl1_0184 48 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 152997069 Common - Xylan 1,4-beta-xylosidase Mmwyl1_3059 104 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 152994741 Common - 4-hydroxybenzoate 3-monooxygenase Mmwyl1_0707 47 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152996117 Common - protein of unknown function DUF1275 Mmwyl1_2095 27 COG3619 COG3619, Predicted membrane protein Function unknown 152997479 Common - N-acylglucosamine 2-epimerase Mmwyl1_3476 38 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 152997539 Common - Auxin Efflux Carrier Mmwyl1_3536 37 COG0679 COG0679, Predicted permeases General function prediction only 152998174 Common - MaoC domain protein dehydratase Mmwyl1_4178 69 COG2030 MaoC, Acyl dehydratase Lipid metabolism 152995709 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_1683 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 152998295 Common - sigma factor regulatory protein, FecR/PupR family Mmwyl1_4300 36 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 152994673 Common - GCN5-related N-acetyltransferase Mmwyl1_0639 146 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 152995693 Common - formyl transferase domain protein Mmwyl1_1667 28 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 152995466 Common - cob(II)yrinic acid a,c-diamide reductase Mmwyl1_1437 112 COG0778 NfnB, Nitroreductase Energy production and conversion 152994427 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0389 57 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996482 Common - alpha/beta hydrolase fold Mmwyl1_2460 16 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152994279 Common - Alcohol dehydrogenase GroES domain protein Mmwyl1_0237 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 152996529 Common - Phage regulatory protein Rha family Mmwyl1_2510 25 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 152996631 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Mmwyl1_2618 207 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 152995803 Common - NUDIX hydrolase Mmwyl1_1778 42 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 152995721 Common - glycosyl transferase family 9 Mmwyl1_1695 98 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 152997118 Common - Monosaccharide-transporting ATPase Mmwyl1_3108 121 COG4158 COG4158, Predicted ABC-type sugar transport system, permease component General function prediction only 152997694 Common - transcriptional regulator, LysR family Mmwyl1_3693 161 COG0583 LysR, Transcriptional regulator Transcription 152997976 Common - protein of unknown function DUF1282 Mmwyl1_3980 24 None None None 152997631 Common - alanine racemase Mmwyl1_3629 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 152997949 Common - hypothetical protein Mmwyl1_3952 3 None None None 152996536 Common - diguanylate cyclase Mmwyl1_2517 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996732 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2719 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997861 Common - hypothetical protein Mmwyl1_3862 13 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152995036 Common - 4'-phosphopantetheinyl transferase Mmwyl1_1005 59 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 152997125 Common - transcriptional regulator, DeoR family Mmwyl1_3115 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 152994100 Common - dihydrolipoamide dehydrogenase Mmwyl1_0058 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 152995390 Common - alpha-L-glutamate ligase, RimK family Mmwyl1_1361 162 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 152994562 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0526 100 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152994998 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Mmwyl1_0967 93 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 152994075 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0032 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 152995969 Common - major facilitator superfamily MFS_1 Mmwyl1_1945 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152998068 Common - amine oxidase Mmwyl1_4072 76 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 152997432 Common - GTP-binding signal recognition particle SRP54 G- domain Mmwyl1_3429 242 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 152995894 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1870 128 COG1609 PurR, Transcriptional regulators Transcription 152996952 Common - intracellular protease, PfpI family Mmwyl1_2941 142 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 152995457 Common - hypothetical protein Mmwyl1_1428 3 None None None 152996613 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Mmwyl1_2600 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 152994299 Common - hypothetical protein Mmwyl1_0257 6 None None None 152996076 Common - Heat shock protein 70 Mmwyl1_2054 233 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 152998105 Common - ABC transporter related Mmwyl1_4109 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152997806 Common - transcriptional regulator, LysR family Mmwyl1_3807 192 COG0583 LysR, Transcriptional regulator Transcription 152997530 Common - aldehyde dehydrogenase Mmwyl1_3527 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997599 Common - protein of unknown function DUF328 Mmwyl1_3597 88 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 152997557 Common - protein of unknown function UPF0227 Mmwyl1_3555 47 COG3150 COG3150, Predicted esterase General function prediction only 152997762 Common - glucose/galactose transporter Mmwyl1_3761 56 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 152994398 Common - Allophanate hydrolase subunit 1 Mmwyl1_0360 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 152998272 Common - ribosomal protein S10 Mmwyl1_4277 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 152994829 Common - lipopolysaccharide biosynthesis protein Mmwyl1_0795 17 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 152996302 Common - D-isomer specific 2-hydroxyacid dehydrogenase catalytic region Mmwyl1_2280 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 152996300 Common - NAD(P)(+) transhydrogenase (AB-specific) Mmwyl1_2278 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 152998423 Common - delta-1-pyrroline-5-carboxylate dehydrogenase Mmwyl1_4428 219 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 152996967 Common - hypothetical protein Mmwyl1_2956 3 None None None 152997774 Common - protein of unknown function DUF21 Mmwyl1_3773 217 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 152994748 Common - hypothetical protein Mmwyl1_0714 11 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 152994787 Common - Imidazoleglycerol-phosphate dehydratase Mmwyl1_0753 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 152996720 Common - protein of unknown function UPF0150 Mmwyl1_2707 13 COG1598 COG1598, Uncharacterized conserved protein Function unknown 152997973 Common - hypothetical protein Mmwyl1_3977 32 None None None 152995246 Nonpathogen - hypothetical protein Mmwyl1_1217 1 None None None 152996172 Common - MotA/TolQ/ExbB proton channel Mmwyl1_2150 141 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 152996789 Common - hypothetical protein Mmwyl1_2776 9 None None None 152994416 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0378 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152997134 Common - putative transcriptional regulator, AsnC family Mmwyl1_3124 151 COG1522 Lrp, Transcriptional regulators Transcription 152997267 Common - ATP-dependent Clp protease adaptor protein ClpS Mmwyl1_3261 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 152995745 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Mmwyl1_1719 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 152997656 Nonpathogen - protein of unknown function DUF526 Mmwyl1_3655 1 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 152997771 Common - ribosomal protein S16 Mmwyl1_3770 209 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 152996404 Common - response regulator receiver modulated metal dependent phosphohydrolase Mmwyl1_2382 223 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 152998191 Common - purine or other phosphorylase family 1 Mmwyl1_4195 64 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 152994636 Common - integral membrane sensor hybrid histidine kinase Mmwyl1_0602 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152994486 Common - extracellular solute-binding protein family 3 Mmwyl1_0449 171 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152994583 Common - protein of unknown function YGGT Mmwyl1_0547 89 COG0762 COG0762, Predicted integral membrane protein Function unknown 152997526 Common - extracellular solute-binding protein family 1 Mmwyl1_3523 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 152998456 Common - ATP synthase F1, epsilon subunit Mmwyl1_4461 191 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 152997970 Common - hypothetical protein Mmwyl1_3973 9 None None None 152997583 Common - flagellar hook capping protein Mmwyl1_3581 118 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 152996997 Common - transcriptional regulator, Fis family Mmwyl1_2986 62 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 152996382 Common - AraC-type transcriptional regulator domain protein Mmwyl1_2360 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996136 Common - DNA topoisomerase I Mmwyl1_2114 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 152998057 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_4061 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152994109 Common - transcriptional regulator, NifA subfamily, Fis Family Mmwyl1_0067 169 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 152997098 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_3088 133 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152997887 Common - nitroreductase Mmwyl1_3889 95 COG0778 NfnB, Nitroreductase Energy production and conversion 152998161 Common - Ion transport protein Mmwyl1_4165 26 None None None 152996598 Common - Thioesterase Mmwyl1_2584 53 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 152995812 Common - phage integrase family protein Mmwyl1_1787 214 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152997194 Common - aldehyde dehydrogenase Mmwyl1_3186 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997841 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3842 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996044 Common - multi-sensor hybrid histidine kinase Mmwyl1_2022 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152994091 Common - succinic semialdehyde dehydrogenase Mmwyl1_0048 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152995692 Common - hypothetical protein Mmwyl1_1666 4 None None None 152994137 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0095 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152996450 Common - RNA-directed DNA polymerase (Reverse transcriptase) Mmwyl1_2428 43 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 152998253 Common - ribosomal protein L30 Mmwyl1_4258 60 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 152998205 Nonpathogen - hypothetical protein Mmwyl1_4209 1 None None None 152996810 Common - dihydrolipoamide dehydrogenase Mmwyl1_2798 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 152995728 Common - Hydroxyacylglutathione hydrolase Mmwyl1_1702 184 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 152994183 Common - putative transcriptional regulator Mmwyl1_0141 40 COG3636 COG3636, Predicted transcriptional regulator Transcription 152997934 Common - sulfate transporter Mmwyl1_3937 156 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 152996600 Common - Integrase catalytic region Mmwyl1_2586 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997885 Common - 3-oxoacyl-(acyl-carrier-protein) reductase, putative Mmwyl1_3887 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152995013 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0982 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995442 Common - cob(I)alamin adenosyltransferase Mmwyl1_1413 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 152995290 Common - putative cold-shock DNA-binding domain protein Mmwyl1_1261 171 COG1278 CspC, Cold shock proteins Transcription 152994445 Common - phage shock B family protein Mmwyl1_0407 21 None None None 152998362 Common - hypothetical protein Mmwyl1_4367 13 COG2932 COG2932, Predicted transcriptional regulator Transcription 152994368 Common - hypothetical protein Mmwyl1_0328 12 None None None 152996054 Common - 2-dehydropantoate 2-reductase Mmwyl1_2032 72 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 152997400 Common - intracellular septation protein A Mmwyl1_3397 82 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 152995935 Common - Uncharacterized protein UPF0065 Mmwyl1_1911 33 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152996123 Common - sodium:neurotransmitter symporter Mmwyl1_2101 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 152997914 Common - Auxin Efflux Carrier Mmwyl1_3917 56 COG0679 COG0679, Predicted permeases General function prediction only 152995622 Common - PfkB domain protein Mmwyl1_1594 161 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 152996801 Common - response regulator receiver modulated diguanylate cyclase/phosphodiesterase Mmwyl1_2788 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152998431 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_4436 79 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152995222 Nonpathogen - hypothetical protein Mmwyl1_1193 1 None None None 152996327 Common - sulphate transporter Mmwyl1_2305 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 152997492 Common - uracil phosphoribosyltransferase Mmwyl1_3489 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 152995524 Common - Class I peptide chain release factor Mmwyl1_1495 114 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 152995741 Common - NADH:ubiquinone oxidoreductase, subunit E Mmwyl1_1715 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 152997650 Common - Antibiotic biosynthesis monooxygenase Mmwyl1_3649 33 COG1359 COG1359, Uncharacterized conserved protein Function unknown 152995641 Common - Cupin 2 conserved barrel domain protein Mmwyl1_1613 81 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997030 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_3019 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152997000 Nonpathogen - hypothetical protein Mmwyl1_2989 1 None None None 152996261 Common - MaoC domain protein dehydratase Mmwyl1_2239 92 COG2030 MaoC, Acyl dehydratase Lipid metabolism 152996806 Common - hypothetical protein Mmwyl1_2793 4 None None None 152994063 Common - 3'(2'),5'-bisphosphate nucleotidase Mmwyl1_0020 175 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 152995823 Common - Uncharacterized protein UPF0065 Mmwyl1_1799 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152997257 Common - uroporphyrin-III C-methyltransferase Mmwyl1_3251 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 152995063 Nonpathogen - hypothetical protein Mmwyl1_1032 5 None None None 152994114 Common - D-lactate dehydrogenase (cytochrome) Mmwyl1_0072 198 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 152996423 Common - AFG1-family ATPase Mmwyl1_2401 102 COG1485 COG1485, Predicted ATPase General function prediction only 152994927 Nonpathogen - hypothetical protein Mmwyl1_0895 1 None None None 152995377 Common - iron-sulfur cluster assembly accessory protein Mmwyl1_1348 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 152994352 Common - type II secretion system protein Mmwyl1_0311 74 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 152994830 Common - protein of unknown function DUF1568 Mmwyl1_0796 38 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 152996685 Common - TRAP transporter solute receptor, TAXI family Mmwyl1_2672 68 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 152996568 Common - 2-hydroxy-3-oxopropionate reductase Mmwyl1_2549 160 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 152996268 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mmwyl1_2246 113 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 152996389 Common - regulatory protein ArsR Mmwyl1_2367 167 COG0640 ArsR, Predicted transcriptional regulators Transcription 152994361 Common - hypothetical protein Mmwyl1_0321 13 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 152995781 Common - transcriptional regulator, LysR family Mmwyl1_1755 99 COG0583 LysR, Transcriptional regulator Transcription 152998245 Common - ribosomal protein L17 Mmwyl1_4250 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 152994858 Common - glucose-1-phosphate thymidylyltransferase Mmwyl1_0826 9 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 152996583 Common - putative transposase subunit Mmwyl1_2565 51 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 152997672 Common - Succinylarginine dihydrolase Mmwyl1_3671 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 152994516 Common - two component transcriptional regulator, winged helix family Mmwyl1_0479 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152994222 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0180 213 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 152997688 Common - hypothetical protein Mmwyl1_3687 3 None None None 152998024 Common - lipoyltransferase and lipoate-protein ligase Mmwyl1_4028 70 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 152994697 Common - putative transcriptional regulator Mmwyl1_0663 2 COG3636 COG3636, Predicted transcriptional regulator Transcription 152996492 Common - putative prophage repressor Mmwyl1_2471 40 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 152997815 Nonpathogen - hypothetical protein Mmwyl1_3816 3 None None None 152995801 Common - hypothetical protein Mmwyl1_1775 9 None None None 152996572 Common - 3-beta hydroxysteroid dehydrogenase/isomerase Mmwyl1_2553 158 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152996655 Common - Metal-dependent hydrolase HDOD Mmwyl1_2642 9 None None None 152994335 Common - ABC-3 protein Mmwyl1_0294 187 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 152997687 Common - fumarate lyase Mmwyl1_3686 212 COG0114 FumC, Fumarase Energy production and conversion 152996464 Common - ATPase Mmwyl1_2442 14 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 152996845 Common - BFD domain protein (2Fe-2S)-binding domain protein Mmwyl1_2833 38 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 152994404 Common - OmpA/MotB domain protein Mmwyl1_0366 163 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 152996890 Common - hypothetical protein Mmwyl1_2878 7 None None None 152994722 Common - isochorismatase hydrolase Mmwyl1_0688 94 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 152994955 Common - 2-methylcitrate synthase/citrate synthase II Mmwyl1_0924 194 COG0372 GltA, Citrate synthase Energy production and conversion 152995965 Common - ribonuclease, Rne/Rng family Mmwyl1_1941 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 152996163 Common - aldo/keto reductase Mmwyl1_2141 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 152997681 Common - Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase Mmwyl1_3680 198 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 152994792 Common - transposase IS3/IS911 family protein Mmwyl1_0758 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152996347 Common - Ectoine/hydroxyectoine ABC transporter permease protein EhuC Mmwyl1_2325 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152995478 Common - RND efflux system, outer membrane lipoprotein, NodT family Mmwyl1_1449 134 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152995624 Common - Xylose isomerase domain protein TIM barrel Mmwyl1_1596 72 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 152997853 Common - protein of unknown function DUF112 transmembrane Mmwyl1_3854 77 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152998458 Common - ATP synthase F1, gamma subunit Mmwyl1_4463 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 152994970 Common - hypothetical protein Mmwyl1_0939 13 COG5470 COG5470, Uncharacterized conserved protein Function unknown 152994624 Nonpathogen - hypothetical protein Mmwyl1_0589 1 None None None 152998117 Common - penicillin-binding protein, 1A family Mmwyl1_4121 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 152996096 Common - MazG nucleotide pyrophosphohydrolase Mmwyl1_2074 42 COG1694 MazG, Predicted pyrophosphatase General function prediction only 152995025 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0994 100 COG2962 RarD, Predicted permeases General function prediction only 152998320 Common - RNA polymerase, sigma 32 subunit, RpoH Mmwyl1_4325 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 152997239 Common - exodeoxyribonuclease V, gamma subunit Mmwyl1_3233 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 152995831 Common - hypothetical protein Mmwyl1_1807 19 COG3794 PetE, Plastocyanin Energy production and conversion 152994084 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0041 131 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152997983 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Mmwyl1_3987 95 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 152994664 Common - ribosomal protein L33 Mmwyl1_0630 142 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 152996032 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2010 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152994700 Common - RelB protein Mmwyl1_0666 3 None None None 152997146 Common - NAD-dependent epimerase/dehydratase Mmwyl1_3137 128 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152994980 Common - inner-membrane translocator Mmwyl1_0949 144 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 152994600 Common - hypothetical protein Mmwyl1_0565 11 None None None 152995639 Common - heavy metal translocating P-type ATPase Mmwyl1_1611 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 152994943 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_0912 120 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152997111 Common - Enoyl-CoA hydratase/isomerase Mmwyl1_3101 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 152994276 Common - Alcohol dehydrogenase GroES domain protein Mmwyl1_0234 213 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 152994557 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0521 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152994862 Common - Phytanoyl-CoA dioxygenase Mmwyl1_0830 9 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 152996356 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit Mmwyl1_2334 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 152996879 Common - protein of unknown function DUF1289 Mmwyl1_2867 14 COG3313 COG3313, Predicted Fe-S protein General function prediction only 152994707 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0673 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 152994376 Common - monooxygenase FAD-binding Mmwyl1_0338 72 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152995211 Common - protein of unknown function DUF796 Mmwyl1_1182 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 152996187 Common - protein of unknown function DUF1315 Mmwyl1_2165 26 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 152996618 Common - mutator MutT protein Mmwyl1_2605 156 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 152994438 Common - 2-isopropylmalate synthase Mmwyl1_0400 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 152994679 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0645 84 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152995420 Nonpathogen - hypothetical protein Mmwyl1_1391 1 None None None 152995945 Common - hypothetical protein Mmwyl1_1921 12 None None None 152994544 Common - protocatechuate 45-dioxygenase alpha subunit Mmwyl1_0508 13 None None None 152997174 Common - FAD dependent oxidoreductase Mmwyl1_3166 91 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152996298 Common - NADH dehydrogenase (ubiquinone) 24 kDa subunit Mmwyl1_2276 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 152996774 Common - glycoside hydrolase family 3 domain protein Mmwyl1_2761 121 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 152997624 Common - sodium ion-translocating decarboxylase, beta subunit Mmwyl1_3622 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 152997275 Common - GCN5-related N-acetyltransferase Mmwyl1_3270 72 COG2153 ElaA, Predicted acyltransferase General function prediction only 152998471 Common - transcriptional regulator, TetR family Mmwyl1_4476 81 COG1309 AcrR, Transcriptional regulator Transcription 152994616 Common - hypothetical protein Mmwyl1_0581 10 None None None 152994757 Common - phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent Mmwyl1_0723 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 152995990 Common - hypothetical protein Mmwyl1_1966 14 None None None 152995082 Common - dimethyladenosine transferase Mmwyl1_1051 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 152997042 Common - DNA polymerase beta domain protein region Mmwyl1_3031 47 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 152994157 Common - 3-hydroxyisobutyrate dehydrogenase Mmwyl1_0115 182 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 152995158 Nonpathogen - ThiS, thiamine-biosynthesis Mmwyl1_1128 5 None None None 152995784 Common - sigma-54 factor interaction domain-containing protein Mmwyl1_1758 155 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 152996127 Common - exsB protein Mmwyl1_2105 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 152995672 Common - hypothetical protein Mmwyl1_1646 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 152998327 Common - homoserine O-acetyltransferase Mmwyl1_4332 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 152995038 Common - cyclic peptide transporter Mmwyl1_1007 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 152997066 Common - transcriptional regulator, LysR family Mmwyl1_3056 193 COG0583 LysR, Transcriptional regulator Transcription 152995445 Nonpathogen - putative phage repressor Mmwyl1_1416 2 COG2932 COG2932, Predicted transcriptional regulator Transcription 152998319 Common - TonB family protein Mmwyl1_4324 38 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 152996763 Nonpathogen - hypothetical protein Mmwyl1_2750 1 None None None 152994816 Common - response regulator receiver protein Mmwyl1_0782 30 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997029 Common - acyl-CoA dehydrogenase domain protein Mmwyl1_3018 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 152997863 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_3864 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152994631 Common - hypothetical protein Mmwyl1_0597 28 COG3081 COG3081, Nucleoid-associated protein General function prediction only 152998250 Common - ribosomal protein L36 Mmwyl1_4255 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 152995645 Common - amino acid adenylation domain Mmwyl1_1617 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152995902 Common - GCN5-related N-acetyltransferase Mmwyl1_1878 21 COG0456 RimI, Acetyltransferases General function prediction only 152994874 Common - Undecaprenyl-phosphate galactose phosphotransferase Mmwyl1_0842 182 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 152995597 Common - protein of unknown function DUF481 Mmwyl1_1569 35 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 152996250 Common - ATP-dependent DNA helicase, RecQ family Mmwyl1_2228 229 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 152995556 Common - hypothetical protein Mmwyl1_1528 10 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 152998469 Common - Alcohol dehydrogenase GroES domain protein Mmwyl1_4474 192 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 152995105 Common - putative transcriptional regulator, AsnC family Mmwyl1_1074 155 COG1522 Lrp, Transcriptional regulators Transcription 152998460 Common - ATP synthase F1, delta subunit Mmwyl1_4465 181 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 152996591 Common - amino acid adenylation domain Mmwyl1_2574 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152996243 Nonpathogen - hypothetical protein Mmwyl1_2221 10 None None None 152994396 Common - Extracellular ligand-binding receptor Mmwyl1_0358 77 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 152995528 Common - hypothetical protein Mmwyl1_1500 7 None None None 152995613 Common - catalase/peroxidase HPI Mmwyl1_1585 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 152997058 Common - coenzyme A transferase Mmwyl1_3047 63 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 152995274 Common - signal peptidase I Mmwyl1_1245 211 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 152996499 Common - flavin reductase domain protein FMN-binding Mmwyl1_2478 119 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 152996393 Common - putative transcriptional regulator, XRE family Mmwyl1_2371 14 COG3655 COG3655, Predicted transcriptional regulator Transcription 152996479 Common - aldehyde dehydrogenase Mmwyl1_2457 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152998006 Common - aminotransferase class I and II Mmwyl1_4010 235 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152995043 Common - iron-sulfur cluster assembly accessory protein Mmwyl1_1012 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 152995049 Common - protein of unknown function UPF0044 Mmwyl1_1018 92 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 152995523 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Mmwyl1_1494 41 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 152997288 Common - major facilitator superfamily MFS_1 Mmwyl1_3283 88 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994412 Common - Glutathione S-transferase domain Mmwyl1_0374 87 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152994954 Common - 2-methylcitrate dehydratase Mmwyl1_0923 56 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 152994378 Common - alkylphosphonate utilization operon protein PhnA Mmwyl1_0340 100 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 152996439 Common - ABC transporter related Mmwyl1_2417 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 152997092 Common - Ornithine cyclodeaminase Mmwyl1_3082 99 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 152996110 Common - alpha amylase catalytic region Mmwyl1_2088 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 152996197 Common - Ornithine decarboxylase Mmwyl1_2175 215 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 152995538 Common - alpha/beta superfamily hydrolase Mmwyl1_1510 6 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 152998396 Common - histidine kinase Mmwyl1_4401 212 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 152995605 Common - Electron transfer flavoprotein alpha subunit Mmwyl1_1577 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 152995798 Common - glycosyltransferase involved in cell wall biogenesis Mmwyl1_1772 36 None None None 152998189 Common - ATP-dependent helicase HrpB Mmwyl1_4193 122 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 152995634 Common - ABC transporter related Mmwyl1_1606 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152996670 Common - NADPH-dependent FMN reductase Mmwyl1_2657 74 COG0431 COG0431, Predicted flavoprotein General function prediction only 152996206 Common - Siderophore-interacting protein Mmwyl1_2184 62 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 152994890 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_0858 110 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996711 Common - Xanthine dehydrogenase molybdopterin binding subunit Mmwyl1_2698 112 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 152997879 Common - hypothetical protein Mmwyl1_3881 28 None None None 152994930 Common - lysine 2,3-aminomutase YodO family protein Mmwyl1_0898 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 152996883 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_2871 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996955 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_2944 115 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152997329 Common - diguanylate phosphodiesterase Mmwyl1_3324 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152995913 Common - diguanylate cyclase Mmwyl1_1889 199 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996430 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Mmwyl1_2408 214 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 152997101 Common - phenylacetate-CoA oxygenase/reductase, PaaK subunit Mmwyl1_3091 153 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 152998312 Common - Phosphoglycerate kinase Mmwyl1_4317 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 152995267 Common - Rieske (2Fe-2S) domain protein Mmwyl1_1238 38 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 152996100 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_2078 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152997523 Common - Ornithine carbamoyltransferase Mmwyl1_3520 161 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 152997385 Common - response regulator receiver modulated diguanylate cyclase/phosphodiesterase Mmwyl1_3382 219 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152994969 Common - hypothetical protein Mmwyl1_0938 19 None None None 152997070 Common - Formaldehyde dehydrogenase glutathione-independent Mmwyl1_3060 192 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 152997133 Common - Transketolase domain protein Mmwyl1_3123 177 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 152997077 Common - succinic semialdehyde dehydrogenase Mmwyl1_3067 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997153 Common - major facilitator superfamily MFS_1 Mmwyl1_3144 7 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994735 Common - sodium/glutamate symporter Mmwyl1_0701 15 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 152995889 Common - D-xylose ABC transporter, periplasmic substrate-binding protein Mmwyl1_1865 99 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 152995541 Common - hypothetical protein Mmwyl1_1513 7 COG4859 COG4859, Uncharacterized protein conserved in bacteria Function unknown 152994723 Common - aminotransferase class I and II Mmwyl1_0689 165 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152997913 Common - 3-dehydroquinate dehydratase, type II Mmwyl1_3916 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 152997619 Common - fumarylacetoacetate (FAA) hydrolase Mmwyl1_3617 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 152996727 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2714 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152996388 Common - exodeoxyribonuclease III Mmwyl1_2366 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 152998348 Common - Peptidoglycan-binding LysM Mmwyl1_4353 18 COG3673 COG3673, Uncharacterized conserved protein Function unknown 152994308 Nonpathogen - hypothetical protein Mmwyl1_0266 1 None None None 152995430 Common - addiction module toxin, Txe/YoeB family Mmwyl1_1401 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 152997870 Common - 4'-phosphopantetheinyl transferase Mmwyl1_3871 4 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 152997665 Common - efflux transporter, RND family, MFP subunit Mmwyl1_3664 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152997705 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_3704 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152997969 Common - SsrA-binding protein Mmwyl1_3972 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 152998098 Common - NMT1/THI5 like domain protein Mmwyl1_4102 116 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 152996897 Common - carboxyl-terminal protease Mmwyl1_2885 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 152995773 Common - prevent-host-death family protein Mmwyl1_1747 15 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 152995190 Common - ectoine hydroxylase Mmwyl1_1161 36 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 152994895 Common - transcriptional regulator, LysR family Mmwyl1_0863 190 COG0583 LysR, Transcriptional regulator Transcription 152997909 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3912 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995326 Common - ferredoxin Mmwyl1_1297 107 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 152997403 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Mmwyl1_3400 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 152994609 Common - phage tail tape measure protein, TP901 family Mmwyl1_0574 24 None None None 152998341 Common - PfkB domain protein Mmwyl1_4346 144 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 152998152 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4156 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152995726 Common - protein of unknown function DUF1255 Mmwyl1_1700 51 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 152996515 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_2496 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996176 Common - protein tyrosine phosphatase Mmwyl1_2154 139 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 152996737 Common - NADH:flavin oxidoreductase/NADH oxidase Mmwyl1_2724 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 152995924 Nonpathogen - hypothetical protein Mmwyl1_1900 3 None None None 152996169 Common - ABC transporter related Mmwyl1_2147 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 152996902 Common - protein of unknown function DUF195 Mmwyl1_2890 142 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 152996151 Common - ribosomal protein L32 Mmwyl1_2129 110 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 152998123 Common - Sporulation domain protein Mmwyl1_4127 16 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 152995146 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_1115 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 152997927 Common - transcriptional regulator, LysR family Mmwyl1_3930 178 COG0583 LysR, Transcriptional regulator Transcription 152996531 Common - hypothetical protein Mmwyl1_2512 2 None None None 152997232 Common - UBA/THIF-type NAD/FAD binding protein Mmwyl1_3226 219 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 152997893 Common - diguanylate cyclase Mmwyl1_3895 175 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152995955 Common - Peptidoglycan-binding domain 1 protein Mmwyl1_1931 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 152997395 Common - two component transcriptional regulator, winged helix family Mmwyl1_3392 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152997126 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_3116 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152995533 Common - cytochrome bd ubiquinol oxidase subunit I Mmwyl1_1505 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 152998134 Common - Inositol phosphatase/fructose-16-bisphosphatase Mmwyl1_4138 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 152994209 Common - RarD protein, DMT superfamily transporter Mmwyl1_0167 97 COG2962 RarD, Predicted permeases General function prediction only 152998146 Common - major facilitator superfamily MFS_1 Mmwyl1_4150 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152998355 Common - hypothetical protein Mmwyl1_4360 10 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152995007 Common - transcriptional regulator, ModE family Mmwyl1_0976 86 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 152995236 Common - hypothetical protein Mmwyl1_1207 11 None None None 152995461 Nonpathogen - hypothetical protein Mmwyl1_1432 2 None None None 152995162 Common - histidinol-phosphate aminotransferase Mmwyl1_1133 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 152994714 Common - Diaminopimelate epimerase Mmwyl1_0680 198 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 152994497 Common - Endoribonuclease L-PSP Mmwyl1_0460 103 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152996109 Common - protein of unknown function UPF0118 Mmwyl1_2087 114 COG0628 PerM, Predicted permease General function prediction only 152997456 Common - dethiobiotin synthase Mmwyl1_3453 162 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 152994199 Common - RimK domain protein ATP-grasp Mmwyl1_0157 73 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 152998222 Common - hydroxymethylbutenyl pyrophosphate reductase Mmwyl1_4227 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 152994147 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0105 92 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152997309 Common - response regulator receiver modulated CheB methylesterase Mmwyl1_3304 220 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 152994802 Common - NAD(P)H dehydrogenase (quinone) Mmwyl1_0768 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 152994987 Common - urease, alpha subunit Mmwyl1_0956 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 152997207 Common - restriction modification system DNA specificity domain Mmwyl1_3199 95 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 152997947 Common - TonB-like protein Mmwyl1_3950 5 None None None 152997051 Common - catechol 1,2-dioxygenase Mmwyl1_3040 50 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 152996909 Common - transcriptional regulator, TetR family Mmwyl1_2897 40 COG1309 AcrR, Transcriptional regulator Transcription 152995199 Common - NUDIX hydrolase Mmwyl1_1170 131 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 152996543 Common - protein of unknown function DUF1706 Mmwyl1_2524 24 COG4283 COG4283, Uncharacterized conserved protein Function unknown 152995713 Common - hypothetical protein Mmwyl1_1687 32 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 152994597 Nonpathogen - hypothetical protein Mmwyl1_0562 1 None None None 152997316 Common - ABC transporter related Mmwyl1_3311 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 152994688 Common - ferrous iron transport protein B Mmwyl1_0654 167 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 152995314 Common - lipid-A-disaccharide synthase Mmwyl1_1285 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 152998270 Common - ribosomal protein L4/L1e Mmwyl1_4275 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 152997281 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_3276 120 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152996757 Common - protein of unknown function DUF925 Mmwyl1_2744 24 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 152997781 Common - hypothetical protein Mmwyl1_3780 8 None None None 152997012 Common - hypothetical protein Mmwyl1_3001 7 None None None 152995221 Nonpathogen - hypothetical protein Mmwyl1_1192 3 None None None 152997824 Common - transcriptional regulator, LysR family Mmwyl1_3825 189 COG0583 LysR, Transcriptional regulator Transcription 152994561 Common - transcriptional regulator, GntR family Mmwyl1_0525 132 COG2188 PhnF, Transcriptional regulators Transcription 152998137 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_4141 99 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 152995673 Common - transcriptional regulator, GntR family Mmwyl1_1647 136 COG2188 PhnF, Transcriptional regulators Transcription 152996620 Common - preprotein translocase, SecA subunit Mmwyl1_2607 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 152994848 Common - hypothetical protein Mmwyl1_0814 19 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 152995574 Common - methionyl-tRNA synthetase Mmwyl1_1546 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152995169 Common - hypothetical protein Mmwyl1_1140 7 None None None 152998260 Common - ribosomal protein L24 Mmwyl1_4265 194 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 152996002 Common - NHL repeat containing protein Mmwyl1_1979 63 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 152997739 Common - protein of unknown function DUF519 Mmwyl1_3738 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 152997574 Common - metal dependent phosphohydrolase Mmwyl1_3572 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 152996874 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_2862 228 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152997431 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG Mmwyl1_3428 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 152997732 Nonpathogen - hypothetical protein Mmwyl1_3731 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 152998412 Common - phosphate binding protein Mmwyl1_4417 120 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 152995002 Common - amidohydrolase 2 Mmwyl1_0971 40 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 152995651 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_1624 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152998055 Common - GTP-binding protein HSR1-related Mmwyl1_4059 19 COG0486 ThdF, Predicted GTPase General function prediction only 152997938 Common - protein of unknown function DUF453 Mmwyl1_3941 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 152998351 Common - hypothetical protein Mmwyl1_4356 2 None None None 152994160 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0118 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998343 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4348 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997562 Common - polysaccharide biosynthesis protein CapD Mmwyl1_3560 150 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152996390 Common - alpha/beta hydrolase fold Mmwyl1_2368 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152995248 Common - hypothetical protein Mmwyl1_1219 4 None None None 152996550 Common - ribonuclease D Mmwyl1_2531 114 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 152998065 Common - hypothetical protein Mmwyl1_4069 20 None None None 152997252 Common - protein of unknown function UPF0005 Mmwyl1_3246 114 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 152995214 Common - hypothetical protein Mmwyl1_1185 2 None None None 152994995 Common - sulfate ABC transporter, ATPase subunit Mmwyl1_0964 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 152997165 Common - Sulfite reductase (ferredoxin) Mmwyl1_3156 172 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 152996016 Common - major facilitator superfamily MFS_1 Mmwyl1_1994 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152995392 Common - hypothetical protein Mmwyl1_1363 12 None None None 152994460 Common - OsmC family protein Mmwyl1_0422 102 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 152995099 Common - putative CheW protein Mmwyl1_1068 178 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 152994481 Common - protein of unknown function DUF1028 Mmwyl1_0444 40 COG3342 COG3342, Uncharacterized conserved protein Function unknown 152995733 Common - Peptidase S49 domain protein Mmwyl1_1707 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 152996162 Common - transcriptional regulator, LysR family Mmwyl1_2140 151 COG0583 LysR, Transcriptional regulator Transcription 152997566 Common - N-acylneuraminate-9-phosphate synthase Mmwyl1_3564 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 152994145 Common - protein of unknown function DUF1456 Mmwyl1_0103 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 152994302 Common - protein of unknown function DUF1526 Mmwyl1_0260 15 None None None 152997283 Nonpathogen - hypothetical protein Mmwyl1_3278 1 None None None 152997295 Common - phosphoesterase PA-phosphatase related Mmwyl1_3290 86 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 152995432 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Mmwyl1_1403 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 152994589 Nonpathogen - hypothetical protein Mmwyl1_0553 1 None None None 152994645 Common - protein of unknown function DUF808 Mmwyl1_0611 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 152997265 Common - translation initiation factor IF-1 Mmwyl1_3259 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 152997572 Common - flagellin domain protein Mmwyl1_3570 122 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 152997324 Common - Thioredoxin domain Mmwyl1_3319 85 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 152997390 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Mmwyl1_3387 226 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 152997221 Common - regulatory protein GntR HTH Mmwyl1_3213 127 COG2186 FadR, Transcriptional regulators Transcription 152997954 Common - transcriptional regulator, LysR family Mmwyl1_3957 175 COG0583 LysR, Transcriptional regulator Transcription 152996121 Common - tRNA--hydroxylase Mmwyl1_2099 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 152996861 Common - protein of unknown function DUF163 Mmwyl1_2849 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 152998011 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Mmwyl1_4015 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 152998193 Common - hypothetical protein Mmwyl1_4197 8 None None None 152996742 Common - 5'-nucleotidase Mmwyl1_2729 30 None None None 152994643 Common - transcriptional regulator, DeoR family Mmwyl1_0609 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 152994338 Common - outer membrane efflux protein Mmwyl1_0297 45 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152995911 Common - diguanylate cyclase Mmwyl1_1887 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994059 Common - methionyl-tRNA formyltransferase Mmwyl1_0016 223 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 152997597 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3595 159 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998086 Common - magnesium and cobalt transport protein CorA Mmwyl1_4090 164 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 152996073 Common - efflux transporter, RND family, MFP subunit Mmwyl1_2051 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152997503 Nonpathogen - hypothetical protein Mmwyl1_3500 1 None None None 152994343 Common - two component transcriptional regulator, winged helix family Mmwyl1_0302 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152996668 Common - ribosomal protein L35 Mmwyl1_2655 25 None None None 152996441 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Mmwyl1_2419 134 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 152996930 Nonpathogen - hypothetical protein Mmwyl1_2919 11 None None None 152994450 Common - Glutathione S-transferase domain Mmwyl1_0412 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152998018 Common - addiction module toxin, Txe/YoeB family Mmwyl1_4022 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 152998308 Common - Adenosylhomocysteine nucleosidase Mmwyl1_4313 97 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 152997540 Common - transcriptional regulator, LysR family Mmwyl1_3537 176 COG0583 LysR, Transcriptional regulator Transcription 152994281 Common - hypothetical protein Mmwyl1_0239 4 None None None 152998042 Common - phosphatidylglycerophosphatase A Mmwyl1_4046 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 152998219 Common - ATP-dependent helicase HrpB Mmwyl1_4224 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 152995400 Common - Integrase catalytic region Mmwyl1_1371 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152995853 Common - ferredoxin Mmwyl1_1829 116 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 152997157 Common - transcriptional regulator, LysR family Mmwyl1_3148 95 COG0583 LysR, Transcriptional regulator Transcription 152995092 Common - glutamine amidotransferase of anthranilate synthase Mmwyl1_1061 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 152995409 Common - Saccharopine dehydrogenase Mmwyl1_1380 51 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 152995795 Common - small multidrug resistance protein Mmwyl1_1769 142 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 152997352 Common - Citrate transporter Mmwyl1_3347 44 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 152994876 Common - peptidylprolyl isomerase FKBP-type Mmwyl1_0844 134 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 152998035 Common - extracellular solute-binding protein family 3 Mmwyl1_4039 163 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152996247 Common - anti-sigma-factor antagonist Mmwyl1_2225 14 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 152995687 Common - tryptophan synthase, alpha subunit Mmwyl1_1661 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 152997414 Common - CcmE/CycJ protein Mmwyl1_3411 95 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 152996063 Common - Phosphoribosylanthranilate isomerase Mmwyl1_2041 200 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 152995987 Common - putative transcriptional regulator, Crp/Fnr family Mmwyl1_1963 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 152995592 Nonpathogen - hypothetical protein Mmwyl1_1564 2 None None None 152995675 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1649 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152998070 Common - protein of unknown function DUF1486 Mmwyl1_4074 26 None None None 152995502 Common - L-carnitine dehydratase/bile acid-inducible protein F Mmwyl1_1473 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 152995960 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Mmwyl1_1936 172 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 152994566 Common - hypothetical protein Mmwyl1_0530 2 None None None 152995816 Common - hypothetical protein Mmwyl1_1791 11 None None None 152997039 Common - multi-sensor hybrid histidine kinase Mmwyl1_3028 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996433 Common - Mammalian cell entry related domain protein Mmwyl1_2411 105 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152996696 Common - dihydrodipicolinate synthetase Mmwyl1_2683 223 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 152997713 Common - transcriptional regulator, LysR family Mmwyl1_3712 188 COG0583 LysR, Transcriptional regulator Transcription 152997648 Common - putative RNA polymerase ECF-type sigma factor Mmwyl1_3646 8 None None None 152997744 Common - GCN5-related N-acetyltransferase Mmwyl1_3743 19 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152996149 Common - maf protein Mmwyl1_2127 191 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 152998242 Common - single-strand binding protein Mmwyl1_4247 200 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 152995077 Common - dihydroneopterin aldolase Mmwyl1_1046 103 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 152998259 Common - ribosomal protein L5 Mmwyl1_4264 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 152997293 Common - Carboxymethylenebutenolidase Mmwyl1_3288 112 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 152995867 Common - GCN5-related N-acetyltransferase Mmwyl1_1843 59 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152997357 Common - transcriptional regulator, TetR family Mmwyl1_3353 14 COG1309 AcrR, Transcriptional regulator Transcription 152997978 Common - NADH dehydrogenase (quinone) Mmwyl1_3982 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 152994888 Common - protein of unknown function DUF861 cupin_3 Mmwyl1_0856 37 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 152994477 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_0440 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152995918 Common - NAD-dependent epimerase/dehydratase Mmwyl1_1894 219 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 152996522 Common - hypothetical protein Mmwyl1_2503 7 None None None 152994471 Common - adenylate kinase Mmwyl1_0433 45 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 152998404 Common - hypothetical protein Mmwyl1_4409 28 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 152996914 Common - hypothetical protein Mmwyl1_2903 16 COG3608 COG3608, Predicted deacylase General function prediction only 152994054 Common - histidinol-phosphate phosphatase family protein Mmwyl1_0011 129 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 152995947 Common - basic membrane lipoprotein Mmwyl1_1923 101 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 152996102 Common - thiamineS protein Mmwyl1_2080 4 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 152998277 Common - DNA-directed RNA polymerase, beta' subunit Mmwyl1_4282 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 152994363 Common - hypothetical protein Mmwyl1_0323 6 None None None 152997463 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3460 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996233 Common - TatD-related deoxyribonuclease Mmwyl1_2211 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 152996024 Common - diaminopimelate decarboxylase Mmwyl1_2002 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 152994807 Common - Oligogalacturonide lyase Mmwyl1_0773 14 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 152994960 Common - Protein of unknown function DUF1826 Mmwyl1_0929 16 None None None 152997776 Common - hypothetical protein Mmwyl1_3775 53 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 152995547 Common - methylated-DNA--protein-cysteine methyltransferase Mmwyl1_1519 212 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 152994520 Nonpathogen - Invasion associated locus B family protein Mmwyl1_0483 7 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 152996576 Common - putative iron-regulated protein Mmwyl1_2557 35 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 152995121 Common - Mannitol dehydrogenase domain Mmwyl1_1090 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 152994530 Common - transcriptional regulator, LysR family Mmwyl1_0494 176 COG0583 LysR, Transcriptional regulator Transcription 152995020 Common - protein of unknown function DUF403 Mmwyl1_0989 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 152995381 Common - Nucleoside-diphosphate kinase Mmwyl1_1352 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 152997397 Common - RNA-binding S4 domain protein Mmwyl1_3394 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 152998385 Common - ATP-dependent DNA helicase RecG Mmwyl1_4390 224 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 152997009 Common - ferredoxin Mmwyl1_2998 41 COG0633 Fdx, Ferredoxin Energy production and conversion 152995177 Common - MotA/TolQ/ExbB proton channel Mmwyl1_1148 100 COG1291 MotA, Flagellar motor component Cell motility and secretion 152995848 Common - hypothetical protein Mmwyl1_1824 9 None None None 152994689 Common - diguanylate cyclase Mmwyl1_0655 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152997514 Nonpathogen - hypothetical protein Mmwyl1_3511 1 None None None 152996634 Nonpathogen - cell division protein FtsL Mmwyl1_2621 3 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 152997659 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mmwyl1_3658 179 COG0388 COG0388, Predicted amidohydrolase General function prediction only 152996345 Common - Ectoine/hydroxyectoine ABC transporter ATP-binding protein Mmwyl1_2323 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152995261 Common - hypothetical protein Mmwyl1_1232 12 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 152996623 Common - cell division protein FtsA Mmwyl1_2610 181 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 152995841 Common - class II aldolase/adducin family protein Mmwyl1_1817 77 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 152997087 Common - aldehyde dehydrogenase Mmwyl1_3077 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994764 Common - ABC transporter related Mmwyl1_0730 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152994979 Common - branched-chain amino acid ABC transporter, putative Mmwyl1_0948 108 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 152996180 Common - Beta-ketoacyl-acyl-carrier-protein synthase I Mmwyl1_2158 198 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 152997639 Common - transport system permease protein Mmwyl1_3637 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152996707 Common - hypothetical protein Mmwyl1_2694 8 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 152996995 Common - MJ0042 family finger-like protein Mmwyl1_2984 16 None None None 152994484 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_0447 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152994422 Nonpathogen - hypothetical protein Mmwyl1_0384 3 None None None 152995932 Common - Domain of unknown function DUF1791 Mmwyl1_1908 15 COG1416 COG1416, Uncharacterized conserved protein Function unknown 152994418 Common - ABC transporter related Mmwyl1_0380 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152995660 Common - Isochorismatase Mmwyl1_1633 56 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 152995937 Common - transcriptional regulator, LysR family Mmwyl1_1913 191 COG0583 LysR, Transcriptional regulator Transcription 152995879 Common - peptide methionine sulfoxide reductase Mmwyl1_1855 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 152998378 Common - response regulator receiver modulated diguanylate phosphodiesterase Mmwyl1_4383 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152997053 Common - muconate and chloromuconate cycloisomerase Mmwyl1_3042 126 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 152996506 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2485 210 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 152995702 Common - hypothetical protein Mmwyl1_1676 3 None None None 152994455 Common - putative transcriptional regulator, AsnC family Mmwyl1_0417 154 COG1522 Lrp, Transcriptional regulators Transcription 152994218 Common - SNARE associated Golgi protein Mmwyl1_0176 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 152997555 Common - yecA family protein Mmwyl1_3553 17 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 152994093 Common - transcriptional regulator, GntR family Mmwyl1_0050 133 COG1802 GntR, Transcriptional regulators Transcription 152994669 Common - inner-membrane translocator Mmwyl1_0635 117 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 152994720 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0686 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996787 Common - hypothetical protein Mmwyl1_2774 3 None None None 152997319 Nonpathogen - hypothetical protein Mmwyl1_3314 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 152995586 Common - branched-chain amino acid aminotransferase Mmwyl1_1558 207 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 152997196 Common - Acyl-CoA dehydrogenase type 2 domain Mmwyl1_3188 42 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 152996468 Nonpathogen - hypothetical protein Mmwyl1_2446 1 None None None 152996769 Common - formyltetrahydrofolate deformylase Mmwyl1_2756 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 152995344 Common - molybdenum cofactor biosynthesis protein A Mmwyl1_1315 198 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 152995814 Nonpathogen - hypothetical protein Mmwyl1_1789 1 None None None 152994614 Common - prophage PSPPH06, putative tail tube protein Mmwyl1_0579 11 None None None 152997590 Common - diaminopimelate decarboxylase Mmwyl1_3588 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 152998142 Common - peptidase S8 and S53 subtilisin kexin sedolisin Mmwyl1_4146 43 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 152995281 Common - RNA methyltransferase, TrmA family Mmwyl1_1252 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 152995526 Common - hypothetical protein Mmwyl1_1498 7 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 152995112 Common - sodium/proline symporter Mmwyl1_1081 180 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 152994634 Common - Ion transport protein Mmwyl1_0600 92 None None None 152996399 Common - sulfatase Mmwyl1_2377 58 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 152997753 Common - ABC transporter related Mmwyl1_3752 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 152996812 Common - 2-oxoglutarate dehydrogenase, E1 subunit Mmwyl1_2800 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 152995224 Common - protein of unknown function DUF796 Mmwyl1_1195 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 152995292 Common - aspartate 1-decarboxylase Mmwyl1_1263 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 152998110 Common - Glutamate synthase (ferredoxin) Mmwyl1_4114 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 152996029 Common - ABC transporter related Mmwyl1_2007 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152996588 Common - cyclic peptide transporter Mmwyl1_2571 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 152994181 Common - transcriptional regulator, LysR family Mmwyl1_0139 183 COG0583 LysR, Transcriptional regulator Transcription 152997494 Common - transposase Mmwyl1_3491 9 None None None 152996330 Common - nicotinate-nucleotide pyrophosphorylase Mmwyl1_2308 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 152997303 Common - response regulator receiver protein Mmwyl1_3298 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152995482 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_1453 42 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152994236 Common - protein of unknown function RIO1 Mmwyl1_0194 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 152994509 Common - permease for cytosine/purines uracil thiamine allantoin Mmwyl1_0472 52 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 152994244 Common - integral membrane sensor hybrid histidine kinase Mmwyl1_0202 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997702 Common - hypothetical protein Mmwyl1_3701 12 None None None 152994839 Common - glycosyl transferase group 1 Mmwyl1_0805 29 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152997693 Common - hypothetical protein Mmwyl1_3692 24 None None None 152996285 Nonpathogen - hypothetical protein Mmwyl1_2263 1 None None None 152996633 Common - Peptidoglycan glycosyltransferase Mmwyl1_2620 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 152998284 Common - preprotein translocase, SecE subunit Mmwyl1_4289 76 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 152996150 Common - protein of unknown function DUF177 Mmwyl1_2128 59 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 152994380 Common - Siderophore-interacting protein Mmwyl1_0342 8 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 152998179 Common - hypothetical protein Mmwyl1_4183 7 None None None 152998155 Common - TRAP transporter, 4TM/12TM fusion protein Mmwyl1_4159 79 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 152995647 Common - ABC transporter related Mmwyl1_1619 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152997652 Common - ATP-dependent DNA helicase Rep Mmwyl1_3651 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 152994692 Common - transcriptional regulator, XRE family Mmwyl1_0658 32 COG1476 COG1476, Predicted transcriptional regulators Transcription 152994785 Common - imidazoleglycerol phosphate synthase, cyclase subunit Mmwyl1_0751 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 152997581 Common - flagellar basal-body rod protein FlgF Mmwyl1_3579 125 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 152997314 Common - protein of unknown function DUF839 Mmwyl1_3309 74 COG3211 PhoX, Predicted phosphatase General function prediction only 152996662 Nonpathogen - hypothetical protein Mmwyl1_2649 1 None None None 152998437 Common - oxidoreductase domain protein Mmwyl1_4442 175 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152996315 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_2293 106 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996413 Common - thiamine-phosphate pyrophosphorylase Mmwyl1_2391 225 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 152996835 Common - type I secretion membrane fusion protein, HlyD family Mmwyl1_2823 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 152994267 Common - hypothetical protein Mmwyl1_0225 14 None None None 152994297 Nonpathogen - hypothetical protein Mmwyl1_0255 13 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 152998334 Common - Exonuclease RNase T and DNA polymerase III Mmwyl1_4339 85 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 152995399 Common - transposase Mmwyl1_1370 9 None None None 152996078 Common - extracellular solute-binding protein family 5 Mmwyl1_2056 189 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152997338 Common - response regulator receiver protein Mmwyl1_3333 70 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997477 Common - lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA Mmwyl1_3474 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 152998293 Common - uracil-xanthine permease Mmwyl1_4298 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 152995052 Common - dihydropteroate synthase Mmwyl1_1021 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 152994573 Common - Auxin Efflux Carrier Mmwyl1_0537 96 COG0679 COG0679, Predicted permeases General function prediction only 152995058 Common - translation initiation factor IF-2 Mmwyl1_1027 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 152995260 Common - diguanylate cyclase Mmwyl1_1231 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152996946 Common - Late embryogenesis abundant protein 2 Mmwyl1_2935 10 COG5608 COG5608, Conserved secreted protein Function unknown 152997244 Nonpathogen - hypothetical protein Mmwyl1_3238 1 None None None 152997803 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Mmwyl1_3804 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 152997537 Common - ABC transporter related Mmwyl1_3534 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152995296 Common - arsenate reductase and related Mmwyl1_1267 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 152997814 Common - TonB-dependent receptor Mmwyl1_3815 130 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 152994946 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_0915 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152994325 Common - homoserine kinase Mmwyl1_0284 63 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 152995667 Nonpathogen - hypothetical protein Mmwyl1_1641 1 None None None 152994429 Common - peptidase M42 family protein Mmwyl1_0391 7 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 152994293 Common - periplasmic binding protein Mmwyl1_0251 141 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 152995716 Nonpathogen - hypothetical protein Mmwyl1_1690 2 None None None 152995860 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1836 57 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996202 Common - Superoxide dismutase Mmwyl1_2180 205 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 152995909 Nonpathogen - hypothetical protein Mmwyl1_1885 1 None None None 152995699 Common - hypothetical protein Mmwyl1_1673 30 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152995383 Nonpathogen - hypothetical protein Mmwyl1_1354 3 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 152997848 Common - addiction module toxin, RelE/StbE family Mmwyl1_3849 31 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 152996159 Common - ABC-2 type transporter Mmwyl1_2137 156 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 152997123 Common - Triose-phosphate isomerase Mmwyl1_3113 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 152997044 Common - Radical SAM domain protein Mmwyl1_3033 20 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 152994996 Common - sulfate ABC transporter, inner membrane subunit CysW Mmwyl1_0965 207 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 152994827 Common - hypothetical protein Mmwyl1_0793 8 None None None 152994125 Common - phenylalanyl-tRNA synthetase, class IIc Mmwyl1_0083 211 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 152995571 Common - electron transport complex, RnfABCDGE type, C subunit Mmwyl1_1543 83 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 152994869 Common - dTDP-glucose 4,6-dehydratase Mmwyl1_0837 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 152996653 Common - OmpA/MotB domain protein Mmwyl1_2640 102 COG1360 MotB, Flagellar motor protein Cell motility and secretion 152994254 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Mmwyl1_0212 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 152997834 Common - Malonyl-CoA decarboxylase Mmwyl1_3835 29 None None None 152994049 Common - transcriptional regulator, HxlR family Mmwyl1_0006 133 COG1733 COG1733, Predicted transcriptional regulators Transcription 152998237 Common - Beta-ketoacyl synthase Mmwyl1_4242 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152994389 Common - prevent-host-death family protein Mmwyl1_0351 46 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 152997528 Common - response regulator receiver protein Mmwyl1_3525 44 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152998111 Common - Sporulation domain protein Mmwyl1_4115 56 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 152994401 Common - protein of unknown function DUF502 Mmwyl1_0363 74 COG2928 COG2928, Uncharacterized conserved protein Function unknown 152996611 Common - Caffeoyl-CoA O-methyltransferase Mmwyl1_2598 99 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 152994881 Common - Domain of unknown function DUF1814 Mmwyl1_0849 9 COG2253 COG2253, Uncharacterized conserved protein Function unknown 152994102 Common - lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase Mmwyl1_0060 85 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 152997706 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_3705 25 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152994917 Common - ABC transporter related Mmwyl1_0885 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152995455 Common - GCN5-related N-acetyltransferase Mmwyl1_1426 6 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 152996965 Common - transposase IS3/IS911 family protein Mmwyl1_2954 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152998390 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_4395 185 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152996570 Common - class II aldolase/adducin family protein Mmwyl1_2551 159 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 152995493 Common - phosphorylase kinase alphabeta Mmwyl1_1464 9 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 152995870 Common - protein of unknown function DUF107 Mmwyl1_1846 5 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 152996987 Common - transcriptional regulator, LysR family Mmwyl1_2976 166 COG0583 LysR, Transcriptional regulator Transcription 152997760 Common - Methenyltetrahydrofolate cyclohydrolase Mmwyl1_3759 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 152997453 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_3450 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152995234 Common - ATPase AAA-2 domain protein Mmwyl1_1205 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 152995300 Common - methionine aminopeptidase, type I Mmwyl1_1271 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 152994208 Common - hypothetical protein Mmwyl1_0166 3 None None None 152994939 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0908 235 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 152996038 Common - extracellular solute-binding protein family 1 Mmwyl1_2016 85 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152994670 Common - cytidine deaminase Mmwyl1_0636 129 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 152996607 Common - ribosomal protein L20 Mmwyl1_2594 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 152995450 Common - pseudouridine synthase Mmwyl1_1421 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 152996771 Common - sarcosine oxidase, alpha subunit family Mmwyl1_2758 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 152997897 Common - imidazolonepropionase Mmwyl1_3900 114 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 152997895 Common - helix-turn-helix domain protein Mmwyl1_3898 54 COG2944 COG2944, Predicted transcriptional regulator Transcription 152996697 Common - TRAP transporter solute receptor, TAXI family Mmwyl1_2684 59 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 152996223 Common - thioesterase superfamily protein Mmwyl1_2201 43 COG0824 FcbC, Predicted thioesterase General function prediction only 152994227 Common - Alanine racemase Mmwyl1_0185 128 COG1609 PurR, Transcriptional regulators Transcription 152996545 Common - putative transcriptional regulator, MerR family Mmwyl1_2526 35 COG0789 SoxR, Predicted transcriptional regulators Transcription 152997286 Common - aldehyde dehydrogenase Mmwyl1_3281 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997234 Common - putative CheW protein Mmwyl1_3228 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 152995473 Common - putative transcriptional regulator, AsnC family Mmwyl1_1444 152 COG1522 Lrp, Transcriptional regulators Transcription 152997437 Common - flagellar biosynthetic protein FliP Mmwyl1_3434 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 152997273 Common - adenylosuccinate lyase Mmwyl1_3268 232 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 152994622 Common - protein of unknown function DUF264 Mmwyl1_0587 27 COG5484 COG5484, Uncharacterized conserved protein Function unknown 152997462 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Mmwyl1_3459 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 152995319 Nonpathogen - hypothetical protein Mmwyl1_1290 5 None None None 152996363 Common - transcriptional regulator, LysR family Mmwyl1_2341 188 COG0583 LysR, Transcriptional regulator Transcription 152998482 Common - ribosomal protein L34 Mmwyl1_4487 35 None None None 152995411 Common - NnrUfamily protein Mmwyl1_1382 32 COG4094 COG4094, Predicted membrane protein Function unknown 152997342 Common - hypothetical protein Mmwyl1_3337 7 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 152998125 Common - heat shock protein HslVU, ATPase subunit HslU Mmwyl1_4129 214 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 152997833 Common - AMP-dependent synthetase and ligase Mmwyl1_3834 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152994860 Common - conserved hypothetical protein, possibly an acyltransferase Mmwyl1_0828 72 COG1043 LpxA, Acyl- acyl carrier protein 152994902 Common - putative PAS/PAC sensor protein Mmwyl1_0870 169 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 152996658 Common - protein-export membrane protein SecD Mmwyl1_2645 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 152995286 Common - peptidase M22 glycoprotease Mmwyl1_1257 185 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 152995855 Common - L-lactate dehydrogenase (cytochrome) Mmwyl1_1831 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 152994677 Common - hypothetical protein Mmwyl1_0643 15 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152997178 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_3170 133 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152997104 Common - phenylacetate-CoA oxygenase, PaaH subunit Mmwyl1_3094 38 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 152996959 Common - GCN5-related N-acetyltransferase Mmwyl1_2948 55 COG0456 RimI, Acetyltransferases General function prediction only 152994919 Common - oxidoreductase domain protein Mmwyl1_0887 161 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152997156 Common - protein of unknown function DUF1302 Mmwyl1_3147 18 None None None 152994155 Common - Nickel-transporting ATPase Mmwyl1_0113 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152995188 Common - diaminobutyrate--2-oxoglutarate aminotransferase Mmwyl1_1159 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 152997300 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3295 10 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995339 Common - phosphoserine phosphatase SerB Mmwyl1_1310 150 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 152996622 Common - cell division protein FtsZ Mmwyl1_2609 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 152998039 Common dddB iron-containing alcohol dehydrogenase Mmwyl1_4043 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 152998147 Common - protein of unknown function DUF81 Mmwyl1_4151 147 COG0730 COG0730, Predicted permeases General function prediction only 152998398 Common - protein of unknown function DUF540 Mmwyl1_4403 38 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 152994801 Common - RNA binding S1 domain protein Mmwyl1_0767 211 COG2183 Tex, Transcriptional accessory protein Transcription 152995091 Common - MgtE intracellular region Mmwyl1_1060 169 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 152996106 Nonpathogen - hypothetical protein Mmwyl1_2084 1 None None None 152994706 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0672 76 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152994112 Common - shikimate 5-dehydrogenase Mmwyl1_0070 218 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 152996936 Common - putative mobilization protein MobD Mmwyl1_2925 18 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 152997793 Common - NAD(+) diphosphatase Mmwyl1_3794 101 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 152995711 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1685 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994985 Common - urease, gamma subunit Mmwyl1_0954 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 152995698 Common - autotransporter-associated beta strand repeat protein Mmwyl1_1672 164 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 152997632 Common - D-amino-acid dehydrogenase Mmwyl1_3630 144 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152997944 Common - Redoxin domain protein Mmwyl1_3947 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 152994613 Common - hypothetical protein Mmwyl1_0578 5 None None None 152996434 Common - protein of unknown function DUF140 Mmwyl1_2412 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 152997734 Common - CinA domain protein Mmwyl1_3733 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 152995953 Common - pseudouridine synthase Rlu family protein, TIGR01621 Mmwyl1_1929 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 152994665 Common - formamidopyrimidine-DNA glycosylase Mmwyl1_0631 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 152995615 Common - hypothetical protein Mmwyl1_1587 14 COG3305 COG3305, Predicted membrane protein Function unknown 152996174 Common - tetraacyldisaccharide 4'-kinase Mmwyl1_2152 126 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 152994977 Common - transcriptional regulator, LysR family Mmwyl1_0946 172 COG0583 LysR, Transcriptional regulator Transcription 152997122 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Mmwyl1_3112 124 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 152994553 Common - succinic semialdehyde dehydrogenase Mmwyl1_0517 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152998313 Common - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Mmwyl1_4318 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 152995479 Common - putative transcriptional regulator, GntR family Mmwyl1_1450 227 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152997013 Common - TonB-dependent receptor plug Mmwyl1_3002 102 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 152994929 Common - beta-lactamase domain protein Mmwyl1_0897 163 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 152997484 Common - glycosyl transferase group 1 Mmwyl1_3481 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152995283 Common - MazG family protein Mmwyl1_1254 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 152994133 Common - Cytochrome o ubiquinol oxidase subunit III Mmwyl1_0091 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 152998172 Common - transcriptional regulator, GntR family Mmwyl1_4176 118 COG2188 PhnF, Transcriptional regulators Transcription 152997698 Common - Cystathionine gamma-synthase Mmwyl1_3697 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 152994712 Common - diacylglycerol kinase Mmwyl1_0678 69 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 152995204 Common - hypothetical protein Mmwyl1_1175 4 None None None 152996755 Nonpathogen - hypothetical protein Mmwyl1_2742 1 None None None 152994904 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0872 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994178 Common - PAS/PAC sensor hybrid histidine kinase Mmwyl1_0136 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997421 Common - hypothetical protein Mmwyl1_3418 9 None None None 152996523 Common - hypothetical protein Mmwyl1_2504 11 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 152994333 Common - putative ferric uptake regulator, Fur family Mmwyl1_0292 132 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 152998417 Common - Alcohol dehydrogenase Mmwyl1_4422 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 152996257 Common - putative hydrolase protein Mmwyl1_2235 35 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 152995254 Common - transcriptional regulator, LysR family Mmwyl1_1225 192 COG0583 LysR, Transcriptional regulator Transcription 152996386 Nonpathogen - hypothetical protein Mmwyl1_2364 1 None None None 152998008 Common - Glutamate--tRNA ligase Mmwyl1_4012 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 152998444 Common - putative transcriptional regulator, GntR family Mmwyl1_4449 118 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152997570 Common - flagellar hook-associated 2 domain protein Mmwyl1_3568 87 COG1345 FliD, Flagellar capping protein Cell motility and secretion 152996713 Common - hypothetical protein Mmwyl1_2700 19 COG3305 COG3305, Predicted membrane protein Function unknown 152995760 Nonpathogen - hypothetical protein Mmwyl1_1734 1 None None None 152994409 Common - Extradiol ring-cleavage dioxygenase class III protein subunit B Mmwyl1_0371 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 152996312 Common - iron-containing alcohol dehydrogenase Mmwyl1_2290 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 152998267 Common - ribosomal protein S19 Mmwyl1_4272 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 152995886 Common - hypothetical protein Mmwyl1_1862 5 None None None 152997444 Common - anti-sigma-factor antagonist Mmwyl1_3441 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 152998350 Common - hypothetical protein Mmwyl1_4355 2 None None None 152994920 Common - Xylose isomerase domain protein TIM barrel Mmwyl1_0888 55 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 152996518 Common - phage tail X family protein Mmwyl1_2499 11 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 152998403 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_4408 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 152995536 Common - ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydD Mmwyl1_1508 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 152995048 Nonpathogen - hypothetical protein Mmwyl1_1017 1 None None None 152994867 Common - UDP-N-acetylglucosamine 2-epimerase Mmwyl1_0835 150 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 152995970 Common - peptidase S15 Mmwyl1_1946 55 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 152994699 Common - putative transcriptional regulator, XRE family Mmwyl1_0665 26 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 152996885 Common - Auxin Efflux Carrier Mmwyl1_2873 113 COG0679 COG0679, Predicted permeases General function prediction only 152997826 Common - Amidase Mmwyl1_3827 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152994458 Common - hypothetical protein Mmwyl1_0420 3 COG3212 COG3212, Predicted membrane protein Function unknown 152994148 Common - hypothetical protein Mmwyl1_0106 4 None None None 152997961 Common - chaperone protein DnaK Mmwyl1_3964 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 152995262 Common - Integrase catalytic region Mmwyl1_1233 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997054 Common - TRAP dicarboxylate transporter, DctP subunit Mmwyl1_3043 96 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996040 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2018 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152996050 Common - transcriptional regulator, TetR family Mmwyl1_2028 85 COG1309 AcrR, Transcriptional regulator Transcription 152994501 Common - transport system permease protein Mmwyl1_0464 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152997405 Nonpathogen - hypothetical protein Mmwyl1_3402 3 None None None 152997416 Common - heme exporter protein CcmC Mmwyl1_3413 126 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 152997662 Common - hydrolase, alpha/beta fold family Mmwyl1_3661 13 COG3904 COG3904, Predicted periplasmic protein Function unknown 152996843 Common - DNA-3-methyladenine glycosylase Mmwyl1_2831 37 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 152997075 Common - aminotransferase class-III Mmwyl1_3065 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 152998101 Common - Dihydroxy-acid dehydratase Mmwyl1_4105 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 152995561 Common - Argininosuccinate synthase Mmwyl1_1533 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 152995915 Common - peptidase M23B Mmwyl1_1891 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 152996204 Common - sulfate adenylyltransferase, small subunit Mmwyl1_2182 143 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 152995374 Common - FeS assembly ATPase SufC Mmwyl1_1345 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 152996083 Common - ABC transporter related Mmwyl1_2061 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152997872 Common - hypothetical protein Mmwyl1_3873 30 None None None 152994077 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0034 117 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152998425 Common - periplasmic iron-binding protein Mmwyl1_4430 32 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152994952 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0921 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997131 Common - type III effector Hrp-dependent outers Mmwyl1_3121 47 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 152995427 Common - hypothetical protein Mmwyl1_1398 13 None None None 152996734 Common - Electron transfer flavoprotein alpha/beta-subunit Mmwyl1_2721 17 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 152998347 Common - ABC transporter related Mmwyl1_4352 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152997349 Common - Lytic transglycosylase catalytic Mmwyl1_3344 134 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 152995431 Common - prevent-host-death family protein Mmwyl1_1402 51 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 152997186 Common - 2-oxo-hepta-3-ene-1,7-dioic acid hydratase Mmwyl1_3178 61 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 152998247 Common - ribosomal protein S4 Mmwyl1_4252 222 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 152994278 Common - diguanylate cyclase Mmwyl1_0236 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996469 Common - hypothetical protein Mmwyl1_2447 21 COG0824 FcbC, Predicted thioesterase General function prediction only 152996596 Common - transposase IS4 family protein Mmwyl1_2582 29 COG5433 COG5433, Transposase DNA replication, recombination, and repair 152995779 Common - rRNA (guanine-N(1)-)-methyltransferase Mmwyl1_1753 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152996891 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2879 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152995276 Common - GTP-binding protein Era Mmwyl1_1247 218 COG1159 Era, GTPase General function prediction only 152998054 Common - hypothetical protein Mmwyl1_4058 9 None None None 152995197 Nonpathogen - hypothetical protein Mmwyl1_1168 1 None None None 152994729 Common - carbohydrate kinase, thermoresistant glucokinase family Mmwyl1_0695 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 152996854 Common - lipoate-protein ligase B Mmwyl1_2842 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 152997388 Common - transcriptional regulator, LysR family Mmwyl1_3385 93 COG0583 LysR, Transcriptional regulator Transcription 152994103 Common - Coproporphyrinogen oxidase Mmwyl1_0061 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 152994546 Common - alpha/beta hydrolase fold Mmwyl1_0510 94 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152995920 Common - putative flavoprotein involved in K+ transport Mmwyl1_1896 66 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 152996973 Nonpathogen - hypothetical protein Mmwyl1_2962 1 None None None 152994765 Common - ABC transporter related Mmwyl1_0731 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152995183 Common - hypothetical protein Mmwyl1_1154 20 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 152995179 Common - Dihydrodipicolinate reductase Mmwyl1_1150 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 152995606 Common - fatty oxidation complex, alpha subunit FadB Mmwyl1_1578 182 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 152998435 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_4440 111 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 152995998 Common - C4-dicarboxylate anaerobic carrier Mmwyl1_1974 38 COG1288 COG1288, Predicted membrane protein Function unknown 152998476 Common - potassium uptake protein, TrkH family Mmwyl1_4481 122 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 152994846 Common - sugar transferase Mmwyl1_0812 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 152995084 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Mmwyl1_1053 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 152998384 Common - transcriptional regulator, LysR family Mmwyl1_4389 190 COG0583 LysR, Transcriptional regulator Transcription 152996580 Common - diguanylate cyclase/phosphodiesterase Mmwyl1_2561 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152995422 Common - 2-alkenal reductase Mmwyl1_1393 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 152996679 Common - Rieske (2Fe-2S) domain protein Mmwyl1_2666 84 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 152998450 Common - extracellular solute-binding protein family 5 Mmwyl1_4455 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152997209 Common - protein of unknown function DUF1016 Mmwyl1_3201 51 COG4804 COG4804, Uncharacterized conserved protein Function unknown 152996292 Nonpathogen - hypothetical protein Mmwyl1_2270 4 None None None 152994844 Common - glycosyl transferase group 1 Mmwyl1_0810 61 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152997094 Common - hypothetical protein Mmwyl1_3084 37 COG4628 COG4628, Uncharacterized conserved protein Function unknown 152996490 Common - YaeQ family protein Mmwyl1_2468 51 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 152996672 Common - Pirin domain protein Mmwyl1_2659 146 COG1741 COG1741, Pirin-related protein General function prediction only 152995174 Common - deoxyxylulose-5-phosphate synthase Mmwyl1_1145 223 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 152997677 Common - aminotransferase class I and II Mmwyl1_3676 160 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 152998468 Common - glucose inhibited division protein A Mmwyl1_4473 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 152997746 Common - Addiction module killer protein HI1419 Mmwyl1_3745 41 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 152995833 Common - globin Mmwyl1_1809 22 COG2346 COG2346, Truncated hemoglobins General function prediction only 152996447 Common - GCN5-related N-acetyltransferase Mmwyl1_2425 8 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 152996877 Common - Trans-2-enoyl-CoA reductase (NAD(+)) Mmwyl1_2865 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 152996039 Common - extracellular solute-binding protein family 5 Mmwyl1_2017 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 152997671 Common - aldehyde dehydrogenase Mmwyl1_3670 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996772 Common - sarcosine oxidase, delta subunit family Mmwyl1_2759 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 152994478 Common - transcriptional regulator, LysR family Mmwyl1_0441 190 COG0583 LysR, Transcriptional regulator Transcription 152995878 Common - Hemolysin-type calcium-binding region Mmwyl1_1854 168 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 152997720 Nonpathogen - hypothetical protein Mmwyl1_3719 3 None None None 152994754 Common - aldehyde dehydrogenase Mmwyl1_0720 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996474 Common - transcriptional regulator, LysR family Mmwyl1_2452 161 COG0583 LysR, Transcriptional regulator Transcription 152997576 Common - flagellar hook-associated protein FlgK Mmwyl1_3574 112 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 152995031 Common - phosphonate ABC transporter, ATPase subunit Mmwyl1_1000 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 152996271 Common - Peptidoglycan-binding domain 1 protein Mmwyl1_2249 5 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 152996574 Common - HI0933 family protein Mmwyl1_2555 137 COG2081 COG2081, Predicted flavoproteins General function prediction only 152996768 Common - FAD linked oxidase domain protein Mmwyl1_2755 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 152996901 Common - cation diffusion facilitator family transporter Mmwyl1_2889 218 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 152995065 Common - hypothetical protein Mmwyl1_1034 10 None None None 152996718 Common - 2OG-Fe(II) oxygenase Mmwyl1_2705 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 152995825 Common - protein of unknown function DUF112 transmembrane Mmwyl1_1801 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152998330 Common - putative oxygen-independent coproporphyrinogen III oxidase Mmwyl1_4335 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 152994778 Common - phosphoribosyl-ATP pyrophosphohydrolase Mmwyl1_0744 179 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 152995107 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Mmwyl1_1076 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 152996148 Common - Patatin Mmwyl1_2126 120 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 152996745 Common - peptidase M48 Ste24p Mmwyl1_2732 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 152994587 Common - Ion transport 2 domain protein Mmwyl1_0551 51 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 152997813 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3814 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995131 Common - sigma E regulatory protein, MucB/RseB Mmwyl1_1100 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 152996500 Common - alpha/beta hydrolase fold Mmwyl1_2479 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152994392 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mmwyl1_0354 248 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 152994394 Common - response regulator receiver modulated metal dependent phosphohydrolase Mmwyl1_0356 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 152997888 Common - Peroxiredoxin Mmwyl1_3890 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 152996978 Common - para-aminobenzoate synthase, subunit I Mmwyl1_2967 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 152995787 Common - histidine kinase Mmwyl1_1761 229 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 152996354 Common - hypothetical protein Mmwyl1_2332 13 None None None 152994355 Common - hypothetical protein Mmwyl1_0314 2 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 152994467 Common - transcriptional regulator, LysR family Mmwyl1_0429 176 COG0583 LysR, Transcriptional regulator Transcription 152997141 Common - hypothetical protein Mmwyl1_3132 19 None None None 152997640 Common - transport system permease protein Mmwyl1_3638 191 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 152994851 Nonpathogen - hypothetical protein Mmwyl1_0818 5 None None None 152995657 Common - L-lysine 6-monooxygenase (NADPH) Mmwyl1_1630 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 152996213 Common - Tol-Pal system TolQ Mmwyl1_2191 122 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 152997685 Common - GCN5-related N-acetyltransferase Mmwyl1_3684 50 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 152997905 Common - peptidase M24 Mmwyl1_3908 93 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 152995355 Common - putative transcriptional regulator, AsnC family Mmwyl1_1326 142 COG1522 Lrp, Transcriptional regulators Transcription 152994215 Common - succinic semialdehyde dehydrogenase Mmwyl1_0173 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152994317 Common - filamentation induced by cAMP protein Fic Mmwyl1_0276 54 COG3177 COG3177, Uncharacterized conserved protein Function unknown 152997952 Common - FAD dependent oxidoreductase Mmwyl1_3955 150 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 152995228 Common - protein of unknown function DUF879 Mmwyl1_1199 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 152997864 Common - GTPase EngC Mmwyl1_3865 163 COG1162 COG1162, Predicted GTPases General function prediction only 152994462 Common - hypothetical protein Mmwyl1_0424 9 None None None 152996663 Common - transcriptional regulator Mmwyl1_2650 11 None None None 152996328 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase Mmwyl1_2306 198 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 152996286 Common - putative ATP-dependent protease Mmwyl1_2264 148 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 152995754 Common - transposase Mmwyl1_1728 9 None None None 152998023 Common - hypothetical protein Mmwyl1_4027 5 None None None 152997612 Common - protein of unknown function DUF152 Mmwyl1_3610 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 152997144 Common - aldehyde dehydrogenase Mmwyl1_3135 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152995636 Common - pentapeptide repeat protein Mmwyl1_1608 53 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 152997151 Common - transporter, putative Mmwyl1_3142 71 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 152996792 Common - Mannitol dehydrogenase domain Mmwyl1_2779 91 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 152994374 Common - Cryptochrome DASH Mmwyl1_0336 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 152996961 Common - Chloramphenicol O-acetyltransferase Mmwyl1_2950 152 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 152994421 Common - transcriptional regulator, LysR family Mmwyl1_0383 142 COG0583 LysR, Transcriptional regulator Transcription 152998333 Common - putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase Mmwyl1_4338 171 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 152994081 Common - Alcohol dehydrogenase GroES domain protein Mmwyl1_0038 214 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 152995610 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_1582 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997063 Common - acetyl-CoA acetyltransferase Mmwyl1_3053 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152997678 Common - cobalamin biosynthesis protein CobD Mmwyl1_3677 150 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 152994400 Common - Amidase Mmwyl1_0362 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152996641 Nonpathogen - hypothetical protein Mmwyl1_2628 1 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 152997985 Common - hypothetical protein Mmwyl1_3989 4 None None None 152997264 Common - Leucyltransferase Mmwyl1_3258 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 152997998 Common - CMP/dCMP deaminase zinc-binding Mmwyl1_4002 224 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 152994819 Common - outer membrane efflux protein Mmwyl1_0785 53 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 152995555 Common - TonB-dependent siderophore receptor Mmwyl1_1527 124 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 152996375 Common - septum site-determining protein MinD Mmwyl1_2353 137 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 152996094 Nonpathogen - hypothetical protein Mmwyl1_2072 2 None None None 152996074 Common - ABC transporter related Mmwyl1_2052 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 152997200 Common - luciferase family protein Mmwyl1_3192 109 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 152996642 Common - HflC protein Mmwyl1_2629 192 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 152994793 Common - Fe(II) trafficking protein YggX Mmwyl1_0759 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 152996509 Common - hypothetical protein Mmwyl1_2488 9 None None None 152996567 Common - transcriptional regulator, DeoR family Mmwyl1_2548 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 152997259 Common - CrcB protein Mmwyl1_3253 186 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 152997787 Common - hypothetical protein Mmwyl1_3786 11 None None None 152994079 Common - GntR domain protein Mmwyl1_0036 137 COG2186 FadR, Transcriptional regulators Transcription 152994251 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0209 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152997862 Common - diguanylate cyclase Mmwyl1_3863 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994245 Common - FAD dependent oxidoreductase Mmwyl1_0203 107 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 152994268 Common - oxidoreductase FAD/NAD(P)-binding domain protein Mmwyl1_0226 83 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 152997166 Common - putative electron transfer flavoprotein-ubiquinone oxidoreductase Mmwyl1_3158 74 None None None 152994575 Common - protein of unknown function DUF179 Mmwyl1_0539 129 COG1678 COG1678, Putative transcriptional regulator Transcription 152996402 Common - Exodeoxyribonuclease I Mmwyl1_2380 52 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 152997046 Nonpathogen - hypothetical protein Mmwyl1_3035 1 None None None 152995395 Common - hypothetical protein Mmwyl1_1366 11 None None None 152995341 Nonpathogen - hypothetical protein Mmwyl1_1312 1 COG2445 COG2445, Uncharacterized conserved protein Function unknown 152998427 Common - two component transcriptional regulator, winged helix family Mmwyl1_4432 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152996666 Common - Asparaginase Mmwyl1_2653 131 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 152994327 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_0286 124 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152995446 Common - protein of unknown function DUF161 Mmwyl1_1417 54 COG1284 COG1284, Uncharacterized conserved protein Function unknown 152997246 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Mmwyl1_3240 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 152996617 Common - response regulator receiver protein Mmwyl1_2604 217 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152994602 Common - hypothetical protein Mmwyl1_0567 5 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 152996604 Common - integration host factor, alpha subunit Mmwyl1_2591 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 152997750 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Mmwyl1_3749 75 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 152996562 Common - 37kDa nucleoid-associated protein Mmwyl1_2543 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 152996736 Common - protein of unknown function DUF224 cysteine-rich region domain protein Mmwyl1_2723 87 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 152996275 Common - diguanylate cyclase Mmwyl1_2253 182 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996455 Common - hypothetical protein Mmwyl1_2433 58 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 152994320 Nonpathogen - hypothetical protein Mmwyl1_0279 1 None None None 152994639 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0605 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152996211 Common - Holliday junction DNA helicase RuvA Mmwyl1_2189 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 152998432 Common - putative transcriptional regulator, GntR family Mmwyl1_4437 161 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152996230 Common - ABC transporter related Mmwyl1_2208 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 152995302 Common - translation elongation factor Ts Mmwyl1_1273 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 152997990 Common - malate--quinone oxidoreductase Mmwyl1_3994 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 152998178 Common - acetyl-CoA acetyltransferase Mmwyl1_4182 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152998208 Common - hypothetical protein Mmwyl1_4212 7 COG5642 COG5642, Uncharacterized conserved protein Function unknown 152995704 Nonpathogen - hypothetical protein Mmwyl1_1678 7 None None None 152997450 Common - flagellar motor switch protein FliG Mmwyl1_3447 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 152995051 Common - ATP-dependent metalloprotease FtsH Mmwyl1_1020 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 152994836 Common - UDP-glucose/GDP-mannose dehydrogenase Mmwyl1_0802 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 152997330 Common - transcriptional regulator, XRE family Mmwyl1_3325 9 COG1396 HipB, Predicted transcriptional regulators Transcription 152997534 Common - UTP-glucose-1-phosphate uridylyltransferase Mmwyl1_3531 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 152997800 Common - pyruvate carboxyltransferase Mmwyl1_3801 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 152997121 Common - inositol monophosphatase Mmwyl1_3111 180 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 152998365 Common - Ion transport protein Mmwyl1_4370 26 None None None 152994064 Common - alpha amylase catalytic region Mmwyl1_0021 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 152995304 Common - ribosome recycling factor Mmwyl1_1275 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 152995573 Common - electron transport complex, RnfABCDGE type, A subunit Mmwyl1_1545 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 152998299 Common - TPR repeat-containing protein Mmwyl1_4304 30 None None None 152997766 Common - Homoserine dehydrogenase Mmwyl1_3765 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 152995700 Common - peptidase M50 Mmwyl1_1674 31 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152997972 Common - prophage MuMc02, peptidase, family S24 Mmwyl1_3976 5 COG2932 COG2932, Predicted transcriptional regulator Transcription 152998339 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4344 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152996929 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_2918 31 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152997262 Common - cell divisionFtsK/SpoIIIE Mmwyl1_3256 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 152996306 Common - glycine cleavage system H protein Mmwyl1_2284 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 152997191 Common - protein of unknown function DUF112 transmembrane Mmwyl1_3183 76 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152994292 Common - TonB-dependent receptor plug Mmwyl1_0250 122 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 152995584 Common - protein of unknown function DUF1294 Mmwyl1_1556 61 COG3326 COG3326, Predicted membrane protein Function unknown 152996047 Common - putative transcriptional regulator, AsnC family Mmwyl1_2025 149 COG1522 Lrp, Transcriptional regulators Transcription 152998028 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_4032 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996911 Nonpathogen - hypothetical protein Mmwyl1_2900 1 None None None 152997206 Nonpathogen - hypothetical protein Mmwyl1_3198 2 None None None 152994271 Common - Glycosyl hydrolase family 32 domain protein Mmwyl1_0229 8 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 152995724 Common - DEAD/DEAH box helicase domain protein Mmwyl1_1698 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152994346 Common - SAF domain protein Mmwyl1_0305 54 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 152995785 Common - HAD-superfamily hydrolase, subfamily IIB Mmwyl1_1759 98 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 152996065 Common - tryptophan synthase, alpha subunit Mmwyl1_2043 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 152997455 Common - transcriptional regulator, Fis family Mmwyl1_3452 17 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152997770 Common - 16S rRNA processing protein RimM Mmwyl1_3769 160 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 152995589 Common - protein of unknown function Spy-related Mmwyl1_1561 22 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 152995495 Common - hypothetical protein Mmwyl1_1466 87 COG1238 COG1238, Predicted membrane protein Function unknown 152994658 Common - DNA repair protein RadC Mmwyl1_0624 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 152995453 Common - multi-sensor hybrid histidine kinase Mmwyl1_1424 221 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 152998188 Common - ferredoxin Mmwyl1_4192 71 COG0633 Fdx, Ferredoxin Energy production and conversion 152996636 Common - MraZ protein Mmwyl1_2623 146 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 152998328 Common - methionine biosynthesis protein MetW Mmwyl1_4333 65 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152996004 Common - putative prophage repressor Mmwyl1_1981 160 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 152996956 Common - alpha/beta hydrolase fold Mmwyl1_2945 41 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152995938 Common - histidine kinase Mmwyl1_1914 23 COG3897 COG3897, Predicted methyltransferase General function prediction only 152998239 Common - phospholipid/glycerol acyltransferase Mmwyl1_4244 17 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 152997727 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_3726 38 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152994993 Common - response regulator receiver protein Mmwyl1_0962 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152997034 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_3023 100 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152998292 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Mmwyl1_4297 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 152995944 Nonpathogen - hypothetical protein Mmwyl1_1920 1 None None None 152996716 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2703 160 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 152998135 Common - flavoprotein WrbA Mmwyl1_4139 105 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 152994744 Nonpathogen - hypothetical protein Mmwyl1_0710 5 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152996407 Common - aldo/keto reductase Mmwyl1_2385 185 COG4989 COG4989, Predicted oxidoreductase General function prediction only 152994309 Common - transposase and inactivated derivatives Mmwyl1_0267 32 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 152998214 Common - FOG domain containing protein Mmwyl1_4219 35 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 152994783 Common - GTP-binding protein HSR1-related Mmwyl1_0749 175 COG0218 COG0218, Predicted GTPase General function prediction only 152996332 Common - phosphate acetyltransferase Mmwyl1_2310 171 COG0280 Pta, Phosphotransacetylase Energy production and conversion 152997391 Common - glutaredoxin-like protein Mmwyl1_3388 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 152994504 Common - hypothetical protein Mmwyl1_0467 7 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 152997845 Common - ketol-acid reductoisomerase Mmwyl1_3846 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 152997359 Nonpathogen - hypothetical protein Mmwyl1_3355 3 None None None 152995118 Common - multi-sensor hybrid histidine kinase Mmwyl1_1087 225 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 152998033 Common - GCN5-related N-acetyltransferase Mmwyl1_4037 157 COG0456 RimI, Acetyltransferases General function prediction only 152997472 Common - protein of unknown function DUF6 transmembrane Mmwyl1_3469 86 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152994825 Common - putative regulator Mmwyl1_0791 9 None None None 152997722 Common - hypothetical protein Mmwyl1_3721 11 None None None 152994948 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0917 132 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152998289 Common - hypothetical protein Mmwyl1_4294 6 None None None 152995079 Common - Rhodanese domain protein Mmwyl1_1048 90 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 152997076 Common - putative transcriptional regulator, AsnC family Mmwyl1_3066 135 COG1522 Lrp, Transcriptional regulators Transcription 152996132 Common - cysteinyl-tRNA synthetase Mmwyl1_2110 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152994190 Common - transcriptional regulator, LysR family Mmwyl1_0148 182 COG0583 LysR, Transcriptional regulator Transcription 152997906 Common - Uncharacterized protein UPF0065 Mmwyl1_3909 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152996208 Common - GreA/GreB family elongation factor Mmwyl1_2186 13 COG0782 GreA, Transcription elongation factor Transcription 152994070 Common - protein of unknown function DUF1037 Mmwyl1_0027 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 152996288 Common - DNA polymerase III, delta prime subunit Mmwyl1_2266 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 152994300 Common - putative transcriptional regulator, GntR family Mmwyl1_0258 211 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152997198 Common - major facilitator superfamily MFS_1 Mmwyl1_3190 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152998377 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_4382 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 152995009 Common - molybdate ABC transporter, inner membrane subunit Mmwyl1_0978 210 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 152995122 Common - ABC transporter related Mmwyl1_1091 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152996785 Common - ABC transporter related Mmwyl1_2772 239 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 152998203 Common - putative signal peptide protein Mmwyl1_4207 6 None None None 152994592 Nonpathogen - hypothetical protein Mmwyl1_0556 1 None None None 152997811 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mmwyl1_3812 84 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 152997376 Common - cobalamin (vitamin B12) biosynthesis CbiG protein Mmwyl1_3373 94 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 152997979 Common - NADH-ubiquinone oxidoreductase chain 4L Mmwyl1_3983 96 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 152998302 Common - ABC transporter related Mmwyl1_4307 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 152998104 Common - Monosaccharide-transporting ATPase Mmwyl1_4108 108 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 152996352 Common - Redoxin domain protein Mmwyl1_2330 182 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 152997038 Common - transcriptional regulator, MarR family Mmwyl1_3027 59 COG1846 MarR, Transcriptional regulators Transcription 152997542 Common - FAD-binding 9 siderophore-interacting domain protein Mmwyl1_3539 62 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 152996999 Common - phosphoribosylamine--glycine ligase Mmwyl1_2988 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 152996871 Common - phosphoserine aminotransferase Mmwyl1_2859 113 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 152995243 Nonpathogen - Peptidoglycan-binding LysM Mmwyl1_1214 2 None None None 152996837 Common - hypothetical protein Mmwyl1_2825 10 None None None 152996992 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Mmwyl1_2981 189 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 152997801 Common - Acetaldehyde dehydrogenase Mmwyl1_3802 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 152996526 Common - phage tail X family protein Mmwyl1_2507 10 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 152994234 Common - HPP family protein? Mmwyl1_0192 73 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 152996336 Common - type II secretion system protein Mmwyl1_2314 5 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 152995166 Common - hypothetical protein Mmwyl1_1137 31 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 152998048 Common - protein of unknown function DUF6 transmembrane Mmwyl1_4052 36 COG2510 COG2510, Predicted membrane protein Function unknown 152995010 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Mmwyl1_0979 140 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 152997496 Common - transcriptional regulator, TetR family Mmwyl1_3493 60 COG1309 AcrR, Transcriptional regulator Transcription 152997911 Common - transcriptional regulator, LysR family Mmwyl1_3914 192 COG0583 LysR, Transcriptional regulator Transcription 152994382 Common - major facilitator superfamily MFS_1 Mmwyl1_0344 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994523 Common - hypothetical protein Mmwyl1_0486 13 None None None 152996814 Common - succinate dehydrogenase, flavoprotein subunit Mmwyl1_2802 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 152995015 Nonpathogen - hypothetical protein Mmwyl1_0984 1 None None None 152995324 Common - transcriptional regulator, GntR family Mmwyl1_1295 133 COG1802 GntR, Transcriptional regulators Transcription 152995226 Common - protein of unknown function DUF877 Mmwyl1_1197 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 152994751 Common - Rhodanese domain protein Mmwyl1_0717 170 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 152997782 Common - Inositol-phosphate phosphatase Mmwyl1_3781 205 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 152996284 Nonpathogen - hypothetical protein Mmwyl1_2262 1 None None None 152997020 Common - TRAP transporter solute receptor, TAXI family Mmwyl1_3009 82 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 152995540 Common - hypothetical protein Mmwyl1_1512 6 COG3779 COG3779, Uncharacterized protein conserved in bacteria Function unknown 152995905 Common - aconitate hydratase 1 Mmwyl1_1881 222 COG1048 AcnA, Aconitase A Energy production and conversion 152997188 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3180 84 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996101 Common - molybdenum cofactor biosynthesis protein C Mmwyl1_2079 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 152994820 Common - ABC transporter related Mmwyl1_0786 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 152996175 Common - protein of unknown function DUF343 Mmwyl1_2153 89 COG2835 COG2835, Uncharacterized conserved protein Function unknown 152997646 Common - protein kinase Mmwyl1_3644 144 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 152994442 Common - ABC transporter related Mmwyl1_0404 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152996831 Common - putative nitrate transport protein Mmwyl1_2819 79 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 152995980 Common - F0F1-ATPase subunit, putative Mmwyl1_1956 17 None None None 152997855 Common - Uncharacterized protein UPF0065 Mmwyl1_3856 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152995962 Common - rod shape-determining protein MreC Mmwyl1_1938 151 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 152994135 Common - protoheme IX farnesyltransferase Mmwyl1_0093 171 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 152995407 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Mmwyl1_1378 80 COG2138 COG2138, Uncharacterized conserved protein Function unknown 152995508 Common - Carboxymuconolactone decarboxylase Mmwyl1_1479 96 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 152996465 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_2443 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995678 Common - glucosamine-6-phosphate isomerase Mmwyl1_1652 87 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 152997240 Common - diguanylate phosphodiesterase Mmwyl1_3234 56 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 152994111 Common - MATE efflux family protein Mmwyl1_0069 162 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 152998053 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_4057 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152998083 Common - Biopolymer transport protein ExbD/TolR Mmwyl1_4087 2 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 152995041 Common - ABC transporter related Mmwyl1_1010 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 152995865 Common - RimK domain protein ATP-grasp Mmwyl1_1841 79 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 152997081 Common - ABC transporter related Mmwyl1_3071 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 152995505 Common - transglutaminase domain protein Mmwyl1_1476 92 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 152994098 Common - hypothetical protein Mmwyl1_0056 4 None None None 152998196 Common - Exonuclease RNase T and DNA polymerase III Mmwyl1_4200 14 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 152994873 Common - glycosyl transferase family 2 Mmwyl1_0841 24 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 152996348 Common - Ectoine/hydroxyEctoine ABC transporter solute-binding protein Mmwyl1_2326 135 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152997588 Common - protein of unknown function DUF484 Mmwyl1_3586 53 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 152994761 Common - Extracellular ligand-binding receptor Mmwyl1_0727 148 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 152995144 Common - extracellular solute-binding protein family 3 Mmwyl1_1113 163 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152996624 Common - Polypeptide-transport-associated domain protein FtsQ-type Mmwyl1_2611 68 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 152996530 Nonpathogen - hypothetical protein Mmwyl1_2511 1 None None None 152996922 Common - protein of unknown function UPF0054 Mmwyl1_2911 190 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 152998071 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mmwyl1_4075 159 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 152994655 Common - acetylglutamate kinase Mmwyl1_0621 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 152995150 Common - hypothetical protein Mmwyl1_1119 15 None None None 152995210 Common - integral membrane sensor hybrid histidine kinase Mmwyl1_1181 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152997365 Nonpathogen - hypothetical protein Mmwyl1_3361 1 None None None 152994554 Common - Dihydroxy-acid dehydratase Mmwyl1_0518 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 152994407 Common - Helix-turn-helix type 11 domain protein Mmwyl1_0369 98 COG2378 COG2378, Predicted transcriptional regulator Transcription 152994206 Common - histidine acid phosphatase Mmwyl1_0164 7 None None None 152995004 Common - hypothetical protein Mmwyl1_0973 14 None None None 152997222 Common - Sporulation domain protein Mmwyl1_3216 4 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 152996238 Common - Haloacid dehalogenase domain protein hydrolase Mmwyl1_2216 37 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 152994171 Common - phospholipase/Carboxylesterase Mmwyl1_0129 51 COG0400 COG0400, Predicted esterase General function prediction only 152994365 Common - hypothetical protein Mmwyl1_0325 16 None None None 152997177 Common - 3,4-dihydroxyphenylacetate 2,3-dioxygenase Mmwyl1_3169 22 COG3384 COG3384, Uncharacterized conserved protein Function unknown 152996231 Common - protein of unknown function DUF214 Mmwyl1_2209 89 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 152997003 Common - hypothetical protein Mmwyl1_2992 49 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 152995389 Common - small GTP-binding protein Mmwyl1_1360 243 COG1160 COG1160, Predicted GTPases General function prediction only 152994581 Common - alanine racemase domain protein Mmwyl1_0545 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 152995558 Common - protein of unknown function DUF454 Mmwyl1_1530 59 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 152994188 Common - hypothetical protein Mmwyl1_0146 22 None None None 152998256 Common - ribosomal protein L6 Mmwyl1_4261 240 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 152997027 Common - thioesterase superfamily protein Mmwyl1_3016 22 COG0824 FcbC, Predicted thioesterase General function prediction only 152997291 Common - GTP cyclohydrolase I Mmwyl1_3286 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 152994435 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_0397 136 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994056 Common - potassium uptake protein, TrkH family Mmwyl1_0013 150 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 152997350 Common - hypothetical protein Mmwyl1_3345 8 None None None 152997113 Common - transcriptional regulator, PaaX family Mmwyl1_3103 33 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 152995330 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Mmwyl1_1301 193 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 152995892 Common - xylulokinase Mmwyl1_1868 184 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 152996199 Common - protein of unknown function DUF395 YeeE/YedE Mmwyl1_2177 70 COG2391 COG2391, Predicted transporter component General function prediction only 152996186 Common - Rhomboid family protein Mmwyl1_2164 46 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 152995512 Common - N-acetyl-gamma-glutamyl-phosphate reductase Mmwyl1_1483 216 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 152996761 Common - hypothetical protein Mmwyl1_2748 10 None None None 152995438 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Mmwyl1_1409 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 152995883 Common - ABC transporter related Mmwyl1_1859 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152995974 Common - Phosphoketolase Mmwyl1_1950 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 152995591 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_1563 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152996907 Common - hypothetical protein Mmwyl1_2895 4 None None None 152996057 Common - FxsA cytoplasmic membrane protein Mmwyl1_2035 71 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 152996569 Common - type III effector Hrp-dependent outers Mmwyl1_2550 60 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 152995361 Common - hypothetical protein Mmwyl1_1332 15 None None None 152994630 Common - hypothetical protein Mmwyl1_0596 3 None None None 152995097 Common - anti-sigma-28 factor, FlgM Mmwyl1_1066 15 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 152995736 Common - dihydroneopterin aldolase Mmwyl1_1710 23 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 152994166 Common - Phosphoglycerate mutase Mmwyl1_0124 103 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 152997271 Common - protein of unknown function DUF489 Mmwyl1_3266 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 152994727 Common - periplasmic binding protein Mmwyl1_0693 101 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 152998047 Common - ATP-cone domain protein Mmwyl1_4051 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 152998151 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_4155 187 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152998062 Common - diguanylate phosphodiesterase Mmwyl1_4066 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152994810 Common - ABC transporter related Mmwyl1_0776 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152996440 Common - RNA polymerase, sigma 54 subunit, RpoN Mmwyl1_2418 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 152996361 Common - arsenate reductase Mmwyl1_2339 119 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 152996246 Common - BolA family protein Mmwyl1_2224 73 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 152994536 Common - protein of unknown function DUF112 transmembrane Mmwyl1_0500 76 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 152995477 Common - efflux transporter, RND family, MFP subunit Mmwyl1_1448 139 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 152997614 Common - competence lipoprotein ComL, putative Mmwyl1_3612 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 152995808 Common - plasmid stabilization system Mmwyl1_1783 22 COG3668 ParE, Plasmid stabilization system protein General function prediction only 152997595 Common - protein of unknown function DUF513 hemX Mmwyl1_3593 48 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 152995181 Common - Deoxyribodipyrimidine photo-lyase Mmwyl1_1152 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 152998230 Common - glutamate 5-kinase Mmwyl1_4235 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 152995024 Common - Na+ antiporter NhaC Mmwyl1_0993 65 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 152997921 Common - aldo/keto reductase Mmwyl1_3924 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 152997710 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_3709 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994449 Common - OsmC family protein Mmwyl1_0411 41 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 152998084 Nonpathogen - Biopolymer transport protein ExbD/TolR Mmwyl1_4088 1 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 152998096 Common - drug resistance transporter, Bcr/CflA subfamily Mmwyl1_4100 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152995154 Common - KpsF/GutQ family protein Mmwyl1_1123 163 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 152995989 Common - carbohydrate kinase, YjeF related protein Mmwyl1_1965 215 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 152995654 Common - ABC transporter related Mmwyl1_1627 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 152996539 Common - cysteine synthase A Mmwyl1_2520 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 152996489 Common - dienelactone hydrolase Mmwyl1_2467 40 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 152995522 Nonpathogen - hypothetical protein Mmwyl1_1493 1 COG5665 NOT5, CCR4-NOT transcriptional regulation complex, NOT5 subunit Transcription 152997719 Common - putative transcriptional regulator, AsnC family Mmwyl1_3718 166 COG1522 Lrp, Transcriptional regulators Transcription 152994353 Common - Tetratricopeptide TPR_2 repeat protein Mmwyl1_0312 30 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 152994926 Common - membrane protein-like protein Mmwyl1_0894 25 COG3671 COG3671, Predicted membrane protein Function unknown 152997505 Common - dTDP-4-dehydrorhamnose reductase Mmwyl1_3502 145 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 152996798 Common - GntR domain protein Mmwyl1_2785 139 COG2186 FadR, Transcriptional regulators Transcription 152997517 Common - Substrate-binding region of ABC-type glycine betaine transport system Mmwyl1_3514 63 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 152996709 Common - prevent-host-death family protein Mmwyl1_2696 17 None None None 152994169 Common - protein of unknown function UPF0131 Mmwyl1_0127 21 COG2105 COG2105, Uncharacterized conserved protein Function unknown 152996014 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_1991 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 152996411 Common - thiazole biosynthesis family protein Mmwyl1_2389 167 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 152996827 Common - nitrite reductase (NAD(P)H), large subunit Mmwyl1_2815 211 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 152994612 Common - hypothetical protein Mmwyl1_0577 4 None None None 152998419 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_4424 72 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152998315 Common - Methionine adenosyltransferase Mmwyl1_4320 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 152994619 Common - phage small terminase subunit Mmwyl1_0584 21 None None None 152994685 Common - sulfate ABC transporter, inner membrane subunit CysT Mmwyl1_0651 231 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 152998145 Common - exodeoxyribonuclease VII, large subunit Mmwyl1_4149 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 152997354 Common - methylmalonate-semialdehyde dehydrogenase Mmwyl1_3349 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997691 Common - MscS Mechanosensitive ion channel Mmwyl1_3690 38 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 152996868 Common - cytidylate kinase Mmwyl1_2856 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 152995406 Common - cobaltochelatase, CobN subunit Mmwyl1_1377 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 152996740 Common - hypothetical protein Mmwyl1_2727 12 None None None 152996425 Common - protein of unknown function DUF34 Mmwyl1_2403 123 COG0327 COG0327, Uncharacterized conserved protein Function unknown 152998282 Common - ribosomal protein L11 Mmwyl1_4287 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 152994910 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_0878 230 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 152995074 Common - GatB/Yqey domain protein Mmwyl1_1043 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 152995298 Common - aminotransferase class I and II Mmwyl1_1269 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 152995447 Common - iron-containing alcohol dehydrogenase Mmwyl1_1418 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 152997486 Common - UDP-glucose/GDP-mannose dehydrogenase Mmwyl1_3483 206 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 152996893 Common - 5'-3' exonuclease Mmwyl1_2881 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 152995012 Common - sodium:dicarboxylate symporter Mmwyl1_0981 156 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 152995644 Common - GreA/GreB family elongation factor Mmwyl1_1616 91 COG0782 GreA, Transcription elongation factor Transcription 152994752 Common - hypothetical protein Mmwyl1_0718 19 None None None 152996436 Common - Na+/Ca+ antiporter, CaCA family Mmwyl1_2414 126 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 152994058 Common - sun protein Mmwyl1_0015 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 152995061 Common - ribosomal protein S15 Mmwyl1_1030 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 152997828 Common - AMP-dependent synthetase and ligase Mmwyl1_3829 196 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 152996406 Common - hypothetical protein Mmwyl1_2384 25 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 152995664 Common - Pyridoxal-dependent decarboxylase Mmwyl1_1637 75 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 152996229 Common - Arylesterase Mmwyl1_2207 106 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 152998442 Common - phosphoesterase PA-phosphatase related Mmwyl1_4447 13 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 152996140 Common - helicase c2 Mmwyl1_2118 135 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 152994715 Common - endo alpha-1,4 polygalactosaminidase precusor Mmwyl1_0681 19 COG3868 COG3868, Uncharacterized conserved protein Function unknown 152995087 Common - hypothetical protein Mmwyl1_1056 5 None None None 152998265 Common - ribosomal protein S3 Mmwyl1_4270 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 152996181 Common - phosphoglucomutase, alpha-D-glucose phosphate-specific Mmwyl1_2159 230 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 152996255 Common - putative transcriptional regulator, Crp/Fnr family Mmwyl1_2233 163 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 152994519 Common - Polypeptide-transport-associated domain protein ShlB-type Mmwyl1_0482 36 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 152997525 Common - spermidine/putrescine ABC transporter ATPase subunit Mmwyl1_3522 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 152996887 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_2875 207 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152995429 Common - prevent-host-death family protein Mmwyl1_1400 25 None None None 152995487 Common - response regulator receiver protein Mmwyl1_1458 86 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152998128 Common - protein of unknown function DUF6 transmembrane Mmwyl1_4132 55 None None None 152995958 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Mmwyl1_1934 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 152996651 Common - Exonuclease RNase T and DNA polymerase III Mmwyl1_2638 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 152996715 Common - ABC transporter related Mmwyl1_2702 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 152995563 Common - Inosine/uridine-preferring nucleoside hydrolase Mmwyl1_1535 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 152994775 Common - Sec-independent protein translocase, TatC subunit Mmwyl1_0741 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 152998345 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4350 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152997660 Common - DNA repair protein RadA Mmwyl1_3659 210 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 152994192 Common - polar amino acid ABC transporter, inner membrane subunit Mmwyl1_0150 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152998206 Nonpathogen - hypothetical protein Mmwyl1_4210 1 None None None 152994452 Common - Antibiotic biosynthesis monooxygenase Mmwyl1_0414 9 COG1359 COG1359, Uncharacterized conserved protein Function unknown 152997278 Common - peptidylprolyl isomerase FKBP-type Mmwyl1_3273 139 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 152996594 Common - 4'-phosphopantetheinyl transferase Mmwyl1_2578 62 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 152997451 Common - flagellar M-ring protein FliF Mmwyl1_3448 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 152995376 Common - cysteine desulfurase, SufS subfamily Mmwyl1_1347 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 152995117 Common - response regulator receiver modulated metal dependent phosphohydrolase Mmwyl1_1086 223 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 152998227 Common - integral membrane protein MviN Mmwyl1_4232 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 152997307 Common - Protein-glutamate O-methyltransferase Mmwyl1_3302 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 152996221 Common - nitroreductase Mmwyl1_2199 83 COG0778 NfnB, Nitroreductase Energy production and conversion 152995433 Nonpathogen - hypothetical protein Mmwyl1_1404 1 None None None 152998121 Common - ribosomal protein L31 Mmwyl1_4125 205 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 152994311 Nonpathogen - hypothetical protein Mmwyl1_0269 1 None None None 152994415 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0377 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152997073 Common - carbohydrate kinase, YjeF related protein Mmwyl1_3063 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 152997966 Common - protein of unknown function UPF0125 Mmwyl1_3969 61 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 152997669 Common - Arginine N-succinyltransferase Mmwyl1_3668 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 152994176 Common - FMN-binding negative transcriptional regulator Mmwyl1_0134 61 COG2808 PaiB, Transcriptional regulator Transcription 152996067 Common - FolC bifunctional protein Mmwyl1_2045 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 152996776 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2763 159 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152994894 Common - hypothetical protein Mmwyl1_0862 36 COG3970 COG3970, Fumarylacetoacetate (FAA) hydrolase family protein General function prediction only 152995232 Common - protein of unknown function DUF876 Mmwyl1_1203 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 152996690 Common - phospholipase D/Transphosphatidylase Mmwyl1_2677 36 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 152997963 Common - DNA repair protein RecN Mmwyl1_3966 200 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 152995917 Common - pseudouridine synthase Mmwyl1_1893 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 152997356 Common - ADP-heptose:LPS heptosyltransferase-like protein Mmwyl1_3351 14 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 152996179 Common - Patatin Mmwyl1_2157 65 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 152997881 Common - monooxygenase FAD-binding Mmwyl1_3883 55 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 152997810 Common - anti-FecI sigma factor, FecR Mmwyl1_3811 38 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 152997268 Common - putative cold-shock DNA-binding domain protein Mmwyl1_3262 176 COG1278 CspC, Cold shock proteins Transcription 152996723 Common - monooxygenase FAD-binding Mmwyl1_2710 79 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152996796 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_2783 56 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152994476 Common - extracellular solute-binding protein family 3 Mmwyl1_0439 144 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152994439 Common - diguanylate cyclase Mmwyl1_0401 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994432 Common - Methyltransferase type 12 Mmwyl1_0394 44 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152997464 Common - replicative DNA helicase Mmwyl1_3461 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 152998368 Common - hypothetical protein Mmwyl1_4373 34 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 152997284 Common - phosphate transporter Mmwyl1_3279 131 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 152995857 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_1833 22 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997236 Common - tryptophanyl-tRNA synthetase Mmwyl1_3230 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152996950 Nonpathogen - cytochrome B561 Mmwyl1_2939 3 COG3038 CybB, Cytochrome B561 Energy production and conversion 152994965 Common - TonB-dependent receptor Mmwyl1_0934 131 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 152994551 Common - DSBA oxidoreductase Mmwyl1_0515 82 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 152997697 Common - extracellular solute-binding protein family 3 Mmwyl1_3696 184 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152995471 Common - MOSC domain containing protein Mmwyl1_1442 20 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 152995951 Nonpathogen - hypothetical protein Mmwyl1_1927 1 None None None 152998094 Common - transcriptional regulator, AraC family Mmwyl1_4098 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997181 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Mmwyl1_3173 32 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 152994886 Common - Haemin-degrading family protein Mmwyl1_0854 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 152995185 Common - membrane protein-like protein Mmwyl1_1156 25 COG3205 COG3205, Predicted membrane protein Function unknown 152996486 Common - alkylhydroperoxidase like protein, AhpD family Mmwyl1_2464 79 COG2128 COG2128, Uncharacterized conserved protein Function unknown 152997173 Common - protein of unknown function DUF1338 Mmwyl1_3165 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 152998149 Common - transcriptional regulator, LysR family Mmwyl1_4153 189 COG0583 LysR, Transcriptional regulator Transcription 152997018 Common - Methyltransferase type 11 Mmwyl1_3007 41 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152997767 Common - Protein-disulfide isomerase-like protein Mmwyl1_3766 65 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 152998372 Common - hypothetical protein Mmwyl1_4377 5 None None None 152997154 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_3145 25 None None None 152995142 Common - transcriptional regulator, AraC family Mmwyl1_1111 146 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152995090 Common - MscS Mechanosensitive ion channel Mmwyl1_1059 173 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 152994922 Common - hypothetical protein Mmwyl1_0890 37 COG4628 COG4628, Uncharacterized conserved protein Function unknown 152994704 Common - lipolytic protein G-D-S-L family Mmwyl1_0670 27 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 152998452 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_4457 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994288 Common - Radical SAM domain protein Mmwyl1_0246 60 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 152997899 Common - urocanate hydratase Mmwyl1_3902 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 152997874 Common - acyl carrier protein, putative Mmwyl1_3875 47 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152994983 Common - ABC transporter related Mmwyl1_0952 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152997736 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mmwyl1_3735 143 COG1146 COG1146, Ferredoxin Energy production and conversion 152997795 Common - conserved hypothetical protein 730 Mmwyl1_3796 44 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 152997248 Common - two component transcriptional regulator, LuxR family Mmwyl1_3242 205 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152997418 Common - heme exporter protein CcmA Mmwyl1_3415 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 152997797 Common - transcriptional regulator, LysR family Mmwyl1_3798 176 COG0583 LysR, Transcriptional regulator Transcription 152996859 Common - rod shape-determining protein RodA Mmwyl1_2847 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 152996966 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_2955 9 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 152995881 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_1857 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152996458 Common - UvrD/REP helicase Mmwyl1_2436 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 152996547 Common - von Willebrand factor type A Mmwyl1_2528 9 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 152998391 Common - ABC transporter related Mmwyl1_4396 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 152996104 Common - phage integrase family protein Mmwyl1_2082 34 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152995928 Common - sodium:dicarboxylate symporter Mmwyl1_1904 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 152994738 Common - metallophosphoesterase Mmwyl1_0704 62 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 152995337 Common - RNA polymerase, sigma 70 subunit, RpoD family Mmwyl1_1308 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 152995722 Common - hypothetical protein Mmwyl1_1696 7 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 152995806 Common - GCN5-related N-acetyltransferase Mmwyl1_1781 11 COG0456 RimI, Acetyltransferases General function prediction only 152997942 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_3945 34 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152998168 Common - ABC transporter related Mmwyl1_4172 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152996841 Common - DTW domain containing protein Mmwyl1_2829 30 COG3148 COG3148, Uncharacterized conserved protein Function unknown 152994667 Common - ABC transporter related Mmwyl1_0633 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 152996511 Common - plasmid maintenance system antidote protein, XRE family Mmwyl1_2491 79 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 152997312 Common - ferredoxin-dependent glutamate synthase Mmwyl1_3307 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 152995463 Nonpathogen - hypothetical protein Mmwyl1_1434 1 None None None 152997578 Common - flagellar P-ring protein Mmwyl1_3576 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 152996498 Common - luciferase family protein Mmwyl1_2477 87 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 152997675 Common - Xanthine phosphoribosyltransferase Mmwyl1_3674 78 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 152995681 Common - putative cold-shock DNA-binding domain protein Mmwyl1_1655 178 COG1278 CspC, Cold shock proteins Transcription 152997991 Common - CBS domain containing protein Mmwyl1_3995 115 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 152995564 Common - RNP-1 like RNA-binding protein Mmwyl1_1536 65 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 152996848 Common - DNA topoisomerase IV, A subunit Mmwyl1_2836 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 152997011 Common - alpha/beta hydrolase fold Mmwyl1_3000 148 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152998233 Common - ribosomal protein L21 Mmwyl1_4238 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 152996905 Common - pseudouridine synthase Mmwyl1_2893 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 152994693 Common - Trp operon repressor Mmwyl1_0659 12 COG2973 TrpR, Trp operon repressor Transcription 152994959 Common - putative transcriptional regulator, AsnC family Mmwyl1_0928 165 COG1522 Lrp, Transcriptional regulators Transcription 152996665 Common - fumarate lyase Mmwyl1_2652 227 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 152997202 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3194 74 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152994791 Common - Integrase catalytic region Mmwyl1_0757 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152995659 Common - 2,3-dihydroxybenzoate-AMP ligase Mmwyl1_1632 221 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 152994795 Common - Disulphide bond formation protein DsbB Mmwyl1_0761 59 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 152996820 Common - phosphoribosylformylglycinamidine cyclo-ligase Mmwyl1_2808 233 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 152994249 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0207 121 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152995202 Common - Cupin 2 conserved barrel domain protein Mmwyl1_1173 131 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995256 Common - protein of unknown function DUF1446 Mmwyl1_1227 36 None None None 152994812 Common - 2-deoxy-D-gluconate 3-dehydrogenase Mmwyl1_0778 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 152996265 Common - modification methylase, HemK family Mmwyl1_2243 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 152996829 Common - nitrate ABC transporter, ATPase subunits C and D Mmwyl1_2817 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 152997512 Common - protein of unknown function DUF480 Mmwyl1_3509 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 152996809 Common - succinyl-CoA synthetase, beta subunit Mmwyl1_2797 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 152995317 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Mmwyl1_1288 195 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 152996587 Common - amino acid adenylation domain Mmwyl1_2570 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 152995604 Common - Electron transfer flavoprotein alpha/beta-subunit Mmwyl1_1576 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 152998287 Common - biotin--acetyl-CoA-carboxylase ligase Mmwyl1_4292 229 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 152994853 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Mmwyl1_0820 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 152998462 Common - ATP synthase F0, C subunit Mmwyl1_4467 67 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 152996802 Common - Citrate carrier protein Mmwyl1_2789 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 152994629 Common - hypothetical protein Mmwyl1_0595 2 None None None 152997142 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mmwyl1_3133 167 COG0388 COG0388, Predicted amidohydrolase General function prediction only 152995650 Common - Isochorismatase Mmwyl1_1623 65 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 152994242 Common - two component transcriptional regulator, winged helix family Mmwyl1_0200 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152996371 Common - translation elongation factor G Mmwyl1_2349 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 152998352 Common - 5'-Nucleotidase domain protein Mmwyl1_4357 140 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 152998408 Common - phosphate uptake regulator, PhoU Mmwyl1_4413 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 152995625 Common - methylmalonate-semialdehyde dehydrogenase Mmwyl1_1597 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996418 Common - putative phosphoheptose isomerase Mmwyl1_2396 119 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 152998003 Common - Leucyl aminopeptidase Mmwyl1_4007 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 152998013 Common - pantoate--beta-alanine ligase Mmwyl1_4017 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 152998106 Common - Monosaccharide-transporting ATPase Mmwyl1_4110 91 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 152996548 Common - protein of unknown function UPF0153 Mmwyl1_2529 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 152997903 Common - cytochrome B561 Mmwyl1_3906 51 COG3658 COG3658, Cytochrome b Energy production and conversion 152998478 Common - AraC-type transcriptional regulator domain protein Mmwyl1_4483 130 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997061 Common - hypothetical protein Mmwyl1_3051 34 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 152996277 Common - copper-translocating P-type ATPase Mmwyl1_2255 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 152995517 Common - GTPase EngC Mmwyl1_1488 154 COG1162 COG1162, Predicted GTPases General function prediction only 152995583 Common - protein of unknown function DUF533 Mmwyl1_1555 38 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 152994526 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0490 144 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152996644 Common - GTP-binding protein HSR1-related Mmwyl1_2631 224 COG2262 HflX, GTPases General function prediction only 152995876 Common - UspA domain protein Mmwyl1_1852 39 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 152998021 Common - protein of unknown function DUF1349 Mmwyl1_4025 28 COG3506 COG3506, Uncharacterized conserved protein Function unknown 152994153 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_0111 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994088 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0045 132 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152994141 Common - hypothetical protein Mmwyl1_0099 12 None None None 152997378 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Mmwyl1_3375 106 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 152994937 Common - regulatory protein LuxR Mmwyl1_0906 24 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 152996018 Common - hypothetical protein Mmwyl1_1996 3 None None None 152996156 Common - Beta-ketoacyl synthase Mmwyl1_2134 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152994590 Nonpathogen - hypothetical protein Mmwyl1_0554 3 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 152994796 Common - regulator of sigma D Mmwyl1_0762 24 COG3160 Rsd, Regulator of sigma D Transcription 152996565 Common - OmpA/MotB domain protein Mmwyl1_2546 169 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 152997344 Nonpathogen - hypothetical protein Mmwyl1_3339 2 None None None 152994225 Common - ABC transporter related Mmwyl1_0183 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 152996852 Common - arginine decarboxylase Mmwyl1_2840 69 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 152996925 Nonpathogen - hypothetical protein Mmwyl1_2914 1 None None None 152995612 Common - permease for cytosine/purines uracil thiamine allantoin Mmwyl1_1584 55 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 152997987 Common - transcription termination factor Rho Mmwyl1_3991 201 COG1158 Rho, Transcription termination factor Transcription 152995708 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mmwyl1_1682 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 152996343 Common - benzoate transporter Mmwyl1_2321 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 152994469 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_0431 63 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152995101 Common - peptidase M23B Mmwyl1_1070 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 152996160 Common - GTP cyclohydrolase I Mmwyl1_2138 108 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 152995250 Nonpathogen - hypothetical protein Mmwyl1_1221 1 None None None 152996377 Common - SMC domain protein Mmwyl1_2355 200 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 152996980 Common - adenylylsulfate reductase, thioredoxin dependent Mmwyl1_2969 167 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 152997790 Common - polysaccharide deacetylase Mmwyl1_3791 93 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 152994676 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_0642 121 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152996273 Common - Radical SAM domain protein Mmwyl1_2251 43 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 152994767 Common - putative structural protein Mmwyl1_0733 17 None None None 152994958 Common - hypothetical protein Mmwyl1_0927 7 None None None 152997106 Common - phenylacetate-CoA ligase Mmwyl1_3096 115 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 152997466 Common - hypothetical protein Mmwyl1_3463 11 None None None 152994406 Common - transcriptional regulator, BadM/Rrf2 family Mmwyl1_0368 56 COG1959 COG1959, Predicted transcriptional regulator Transcription 152994105 Common - protein of unknown function DUF482 Mmwyl1_0063 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 152994304 Common - transcriptional regulator, AraC family Mmwyl1_0262 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152997025 Common - Electron transfer flavoprotein alpha subunit Mmwyl1_3014 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 152995086 Common - heat shock protein DnaJ domain protein Mmwyl1_1055 102 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 152997382 Common - Cobyrinic acid ac-diamide synthase Mmwyl1_3379 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 152997501 Common - transcriptional regulator, LysR family Mmwyl1_3498 183 COG0583 LysR, Transcriptional regulator Transcription 152995033 Common - two component, sigma54 specific, transcriptional regulator, Fis family Mmwyl1_1002 215 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152995137 Common - (Glutamate--ammonia-ligase) adenylyltransferase Mmwyl1_1106 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 152997623 Common - putative cold-shock DNA-binding domain protein Mmwyl1_3621 181 COG1278 CspC, Cold shock proteins Transcription 152997446 Nonpathogen - hypothetical protein Mmwyl1_3443 1 None None None 152997917 Common - Protocatechuate 4,5-dioxygenase Mmwyl1_3920 31 COG3384 COG3384, Uncharacterized conserved protein Function unknown 152996294 Common - HtpX domain protein Mmwyl1_2272 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 152996326 Common - ribonuclease, Rne/Rng family Mmwyl1_2304 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 152996918 Common - protein of unknown function DUF55 Mmwyl1_2907 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 152995264 Common - carboxylate/amino acid/amine transporter Mmwyl1_1235 46 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152995997 Common - OmpA/MotB domain protein Mmwyl1_1973 161 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 152994604 Nonpathogen - hypothetical protein Mmwyl1_0569 1 None None None 152995940 Common - sulfatase Mmwyl1_1916 65 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 152996989 Common - hypothetical protein Mmwyl1_2978 21 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 152996193 Common - Endoribonuclease L-PSP Mmwyl1_2171 127 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152997920 Common - oxidoreductase domain protein Mmwyl1_3923 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152996037 Common - Beta-galactosidase Mmwyl1_2015 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 152995288 Common - protein of unknown function DUF548 Mmwyl1_1259 49 None None None 152998439 Common - UvrD/REP helicase Mmwyl1_4444 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 152995649 Common - isochorismate synthase Mmwyl1_1621 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 152996092 Common - multiple antibiotic resistance (MarC)-related protein Mmwyl1_2070 113 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 152998474 Common - two component transcriptional regulator, winged helix family Mmwyl1_4479 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152994900 Common - protein of unknown function DUF442 Mmwyl1_0868 105 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 152997604 Common - outer membrane lipoprotein LolB Mmwyl1_3602 51 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 152994803 Common - transcriptional regulator, LysR family Mmwyl1_0769 155 COG0583 LysR, Transcriptional regulator Transcription 152994548 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_0512 60 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152995752 Common - histone family protein DNA-binding protein Mmwyl1_1726 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 152996446 Common - hypothetical protein Mmwyl1_2424 3 COG3499 COG3499, Phage protein U General function prediction only 152995835 Common - redox-active disulfide protein 2 Mmwyl1_1811 58 None None None 152995336 Common - peptidase M23B Mmwyl1_1307 189 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 152996627 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Mmwyl1_2614 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 152994220 Common - transcriptional regulator, LysR family Mmwyl1_0178 172 COG0583 LysR, Transcriptional regulator Transcription 152996476 Common - amidohydrolase Mmwyl1_2454 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 152997764 Common - protein of unknown function DUF558 Mmwyl1_3763 17 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 152995172 Common - C4-dicarboxylate anaerobic carrier Mmwyl1_1143 50 COG1288 COG1288, Predicted membrane protein Function unknown 152995884 Common - oxidoreductase domain protein Mmwyl1_1860 154 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152995792 Common - HopJ type III effector protein Mmwyl1_1766 15 None None None 152996681 Common - Oxidoreductase FAD-binding domain protein Mmwyl1_2668 154 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 152997726 Common - hypothetical protein Mmwyl1_3725 4 None None None 152996031 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_2009 158 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152996875 Common - peptidase M16 domain protein Mmwyl1_2863 193 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 152997097 Common - TRAP dicarboxylate transporter- DctP subunit Mmwyl1_3087 62 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 152996338 Common - dephospho-CoA kinase Mmwyl1_2316 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 152996688 Common - Cupin 2 conserved barrel domain protein Mmwyl1_2675 29 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 152997600 Common - modification methylase, HemK family Mmwyl1_3598 228 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 152997630 Common - alanyl-tRNA synthetase Mmwyl1_3628 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152994502 Common - transport system permease protein Mmwyl1_0465 191 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 152996766 Common - BLUF domain protein Mmwyl1_2753 39 None None None 152995138 Common - SbmABacA family protein Mmwyl1_1107 57 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 152995109 Common - pyruvate kinase Mmwyl1_1078 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 152994776 Common - twin-arginine translocation protein, TatB subunit Mmwyl1_0742 39 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 152994424 Nonpathogen - hypothetical protein Mmwyl1_0386 1 None None None 152995863 Common - Endoribonuclease L-PSP Mmwyl1_1839 86 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 152997080 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_3070 140 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152995631 Nonpathogen - dual specificity protein phosphatase Mmwyl1_1603 3 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 152994510 Common - regulatory protein IclR Mmwyl1_0473 56 COG1414 IclR, Transcriptional regulator Transcription 152995070 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Mmwyl1_1039 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 152997757 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Mmwyl1_3756 120 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 152994386 Common - transcriptional regulator, HxlR family Mmwyl1_0348 144 COG1733 COG1733, Predicted transcriptional regulators Transcription 152998051 Common - protein of unknown function DUF6 transmembrane Mmwyl1_4055 47 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 152995810 Common - hypothetical protein Mmwyl1_1785 4 None None None 152994935 Common - GCN5-related N-acetyltransferase Mmwyl1_0904 22 COG0456 RimI, Acetyltransferases General function prediction only 152997032 Common - Acetyl-CoA C-acetyltransferase Mmwyl1_3021 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152997406 Common - serine O-acetyltransferase Mmwyl1_3403 188 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 152996236 Common - hypothetical protein Mmwyl1_2214 12 COG0730 COG0730, Predicted permeases General function prediction only 152994878 Common - glycosyl transferase group 1 Mmwyl1_0846 203 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 152998185 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_4189 98 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 152994534 Common - Uncharacterized protein UPF0065 Mmwyl1_0498 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 152997362 Common - hypothetical protein Mmwyl1_3358 2 None None None 152994187 Nonpathogen - hypothetical protein Mmwyl1_0145 1 None None None 152996460 Common - hypothetical protein Mmwyl1_2438 32 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 152994107 Common - Glutathione S-transferase domain Mmwyl1_0065 95 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152994823 Common - protein of unknown function DUF940 membrane lipoprotein putative Mmwyl1_0789 21 None None None 152997918 Common - Extradiol ring-cleavage dioxygenase LigAB LigA subunit Mmwyl1_3921 13 None None None 152994072 Common - oxidoreductase domain protein Mmwyl1_0029 160 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152997474 Common - thiamine ABC transporter, inner membrane subunit Mmwyl1_3471 146 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 152995581 Common - NUDIX hydrolase Mmwyl1_1553 16 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 152995124 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_1093 161 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 152996167 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Mmwyl1_2145 210 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 152998375 Common - hypothetical protein Mmwyl1_4380 7 None None None 152998201 Common - transposase IS4 family protein Mmwyl1_4205 29 None None None 152996502 Common - transcriptional regulator, GntR family Mmwyl1_2481 130 COG1802 GntR, Transcriptional regulators Transcription 152994139 Common - secretion protein HlyD family protein Mmwyl1_0097 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 152994384 Common - GCN5-related N-acetyltransferase Mmwyl1_0346 9 COG2153 ElaA, Predicted acyltransferase General function prediction only 152998114 Common - type II and III secretion system protein Mmwyl1_4118 132 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 152994121 Nonpathogen - hypothetical protein Mmwyl1_0079 5 None None None 152994175 Common - diguanylate cyclase Mmwyl1_0133 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152994718 Common - transcriptional regulator, LysR family Mmwyl1_0684 151 COG0583 LysR, Transcriptional regulator Transcription 152996042 Common - ABC transporter related Mmwyl1_2020 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 152997498 Common - putative glutathione S-transferase Mmwyl1_3495 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152996138 Nonpathogen - hypothetical protein Mmwyl1_2116 1 None None None 152996480 Common - SMC domain protein Mmwyl1_2458 31 COG3910 COG3910, Predicted ATPase General function prediction only 152997095 Common - transcriptional regulator, LysR family Mmwyl1_3085 191 COG0583 LysR, Transcriptional regulator Transcription 152995053 Common - phosphoglucosamine mutase Mmwyl1_1022 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 152998280 Common - ribosomal protein L10 Mmwyl1_4285 209 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 152994266 Common - two component transcriptional regulator, winged helix family Mmwyl1_0224 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152995743 Common - ApbE family lipoprotein Mmwyl1_1717 141 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 152997777 Common - protein of unknown function DUF72 Mmwyl1_3776 92 COG1801 COG1801, Uncharacterized conserved protein Function unknown 152995417 Common - hypothetical protein Mmwyl1_1388 14 None None None 152996639 Common - Adenylosuccinate synthase Mmwyl1_2626 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 152995748 Common - trigger factor Mmwyl1_1722 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 152996088 Nonpathogen - hypothetical protein Mmwyl1_2066 1 None None None 152996968 Common - hypothetical protein Mmwyl1_2957 2 None None None 152996783 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_2770 122 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 152996686 Common - TRAP transporter, 4TM/12TM fusion protein Mmwyl1_2673 107 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 152997036 Common - hypothetical protein Mmwyl1_3025 17 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 152997807 Common - major facilitator superfamily MFS_1 Mmwyl1_3808 86 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152997628 Common - carbon storage regulator, CsrA Mmwyl1_3626 82 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 152995497 Nonpathogen - hypothetical protein Mmwyl1_1468 2 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 152996210 Common - crossover junction endodeoxyribonuclease RuvC Mmwyl1_2188 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 152995348 Common - acetolactate synthase, large subunit, biosynthetic type Mmwyl1_1319 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 152995747 Common - putative ribonuclease BN Mmwyl1_1721 79 COG1295 Rbn, Predicted membrane protein Function unknown 152995366 Common - NADH:flavin oxidoreductase/NADH oxidase Mmwyl1_1337 203 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 152996130 Common - branched-chain amino acid transport Mmwyl1_2108 29 COG4392 COG4392, Predicted membrane protein Function unknown 152996816 Common - Succinate dehydrogenase cytochrome b556 subunit Mmwyl1_2804 73 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 152994974 Common - Na+ antiporter NhaC Mmwyl1_0943 42 COG2056 COG2056, Predicted permease General function prediction only 152995156 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family Mmwyl1_1125 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 152996334 Common - hypothetical protein Mmwyl1_2312 3 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 152994610 Nonpathogen - hypothetical protein Mmwyl1_0575 1 None None None 152996593 Common - IS630 ORF Mmwyl1_2577 27 None None None 152997843 Common - extracellular solute-binding protein family 1 Mmwyl1_3844 127 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 152996052 Common - protein of unknown function DUF1415 Mmwyl1_2030 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 152996478 Common - creatinase Mmwyl1_2456 160 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 152994426 Common - Methionine synthase vitamin-B12 independent Mmwyl1_0388 144 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 152994525 Common - GCN5-related N-acetyltransferase Mmwyl1_0488 125 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 152994488 Common - Amidase Mmwyl1_0451 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 152998420 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_4425 125 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 152996839 Common - periplasmic protein-like protein Mmwyl1_2827 34 COG3672 COG3672, Predicted periplasmic protein Function unknown 152994781 Common - diguanylate cyclase Mmwyl1_0747 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996517 Common - hypothetical protein Mmwyl1_2498 3 COG3500 COG3500, Phage protein D General function prediction only 152995017 Common - transglutaminase domain protein Mmwyl1_0986 108 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 152997610 Common - hypothetical protein Mmwyl1_3608 15 None None None 152995627 Common - oxidoreductase domain protein Mmwyl1_1599 131 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 152996395 Common - hypothetical protein Mmwyl1_2373 7 COG4727 COG4727, Uncharacterized protein conserved in bacteria Function unknown 152997260 Common - AAA ATPase central domain protein Mmwyl1_3254 236 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 152996615 Common - protein of unknown function DUF442 Mmwyl1_2602 41 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 152997931 Common - hypothetical protein Mmwyl1_3934 15 COG5553 COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily General function prediction only 152997830 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_3831 201 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 152997048 Common - transcriptional regulator, LysR family Mmwyl1_3037 174 COG0583 LysR, Transcriptional regulator Transcription 152995397 Common - DinB family protein Mmwyl1_1368 39 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 152998326 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_4331 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152996049 Common - drug resistance transporter, EmrB/QacA subfamily Mmwyl1_2027 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152996942 Common - protein of unknown function DUF330 Mmwyl1_2931 22 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 152998159 Common - two component transcriptional regulator, winged helix family Mmwyl1_4163 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152997310 Common - Integrase catalytic region Mmwyl1_3305 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997839 Common - diguanylate cyclase Mmwyl1_3840 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 152997730 Common - cyanate lyase Mmwyl1_3729 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 152997866 Common - Glutathione S-transferase domain Mmwyl1_3867 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 152997959 Common - Rieske (2Fe-2S) domain protein Mmwyl1_3962 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 152997551 Common - CRISPR-associated helicase Cas3 Mmwyl1_3548 71 COG1203 COG1203, Predicted helicases General function prediction only 152994822 Common - protein of unknown function DUF1568 Mmwyl1_0788 26 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 152997331 Common - channel protein, hemolysin III family Mmwyl1_3326 118 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 152997137 Common - protein of unknown function DUF980 Mmwyl1_3127 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 152998297 Common - hypothetical protein Mmwyl1_4302 5 None None None 152994865 Common - acyltransferase 3 Mmwyl1_0833 52 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 152998309 Nonpathogen - hypothetical protein Mmwyl1_4314 1 None None None 152997491 Common - ATP-dependent protease La Mmwyl1_3488 198 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 152994045 Common - DNA polymerase III, beta subunit Mmwyl1_0002 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 152997427 Common - response regulator receiver modulated CheB methylesterase Mmwyl1_3424 211 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 152994493 Common - protein of unknown function DUF861 cupin_3 Mmwyl1_0456 11 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 152995029 Common - phosphonate ABC transporter, inner membrane subunit Mmwyl1_0998 93 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 152995451 Common - hypothetical protein Mmwyl1_1422 15 None None None 152995695 Common - phage Tail Collar domain protein Mmwyl1_1669 35 COG4675 MdpB, Microcystin-dependent protein Function unknown 152995579 Nonpathogen - hypothetical protein Mmwyl1_1551 2 None None None 152996602 Nonpathogen - hypothetical protein Mmwyl1_2589 1 None None None 152998394 Common - 4-hydroxybenzoate polyprenyl transferase Mmwyl1_4399 190 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 152997752 Common - putative signal transduction protein Mmwyl1_3751 56 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 152996990 Common - Tetratricopeptide TPR_2 repeat protein Mmwyl1_2979 3 None None None 152994263 Common - glutathione-dependent formaldehyde-activating GFA Mmwyl1_0221 65 COG3791 COG3791, Uncharacterized conserved protein Function unknown 152994788 Common - AsmA family protein Mmwyl1_0754 54 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 152994414 Common - hypothetical protein Mmwyl1_0376 25 COG5477 COG5477, Predicted small integral membrane protein Function unknown 152995127 Nonpathogen - hypothetical protein Mmwyl1_1096 1 None None None 152996428 Common - Histidinol dehydrogenase Mmwyl1_2406 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 152996453 Common - Phosphoribosyl-AMP cyclohydrolase Mmwyl1_2431 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 152996319 Common - phosphatase-like protein Mmwyl1_2297 43 COG3211 PhoX, Predicted phosphatase General function prediction only 152997372 Nonpathogen - hypothetical protein Mmwyl1_3369 1 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 152995306 Common - phosphatidate cytidylyltransferase Mmwyl1_1277 214 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 152996913 Common - alpha/beta hydrolase fold Mmwyl1_2902 17 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 152995551 Nonpathogen - hypothetical protein Mmwyl1_1523 3 None None None 152995459 Common - GCN5-related N-acetyltransferase Mmwyl1_1430 70 COG2153 ElaA, Predicted acyltransferase General function prediction only 152995827 Common - integral membrane sensor signal transduction histidine kinase Mmwyl1_1803 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 152998290 Common - Beta-glucosidase Mmwyl1_4295 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 152998367 Common - hypothetical protein Mmwyl1_4372 21 COG1700 COG1700, Uncharacterized conserved protein Function unknown 152995152 Common - Succinylglutamate desuccinylase/aspartoacylase Mmwyl1_1121 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 152994229 Common - diguanylate cyclase with PAS/PAC sensor Mmwyl1_0187 180 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152996747 Common - Beta-galactosidase Mmwyl1_2734 75 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 152996304 Common - glycine cleavage system T protein Mmwyl1_2282 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 152997041 Common - inositol monophosphatase Mmwyl1_3030 183 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 152998093 Nonpathogen - Lysine exporter protein (LYSE/YGGA) Mmwyl1_4097 2 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152998001 Common - valyl-tRNA synthetase Mmwyl1_4005 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152996804 Common - response regulator receiver and unknown domain protein Mmwyl1_2791 199 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 152998337 Common - ABC transporter related Mmwyl1_4342 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152997457 Common - Methyltransferase type 11 Mmwyl1_3454 175 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 152998069 Common - short-chain dehydrogenase/reductase SDR Mmwyl1_4073 231 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 152997740 Common - diguanylate cyclase Mmwyl1_3739 116 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 152998274 Common - translation elongation factor G Mmwyl1_4279 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 152996982 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Mmwyl1_2971 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 152995766 Common - formyltetrahydrofolate deformylase Mmwyl1_1740 215 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 152996484 Nonpathogen - hypothetical protein Mmwyl1_2462 6 None None None 152994564 Common - hypothetical protein Mmwyl1_0528 2 None None None 152995874 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Mmwyl1_1850 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 152995514 Common - putative transcriptional regulator, fis family protein Mmwyl1_1485 9 None None None 152994118 Nonpathogen - response regulator receiver protein Mmwyl1_0076 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 152994913 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_0881 128 COG1609 PurR, Transcriptional regulators Transcription 152996081 Common - ABC transporter related Mmwyl1_2059 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 152994578 Common - aspartate carbamoyltransferase Mmwyl1_0542 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 152997532 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_3529 82 COG1279 COG1279, Lysine efflux permease General function prediction only 152996217 Common - Peptidoglycan-associated lipoprotein Mmwyl1_2195 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 152995230 Common - putative FHA domain containing protein Mmwyl1_1201 14 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 152994257 Common - transcriptional regulator, TetR family Mmwyl1_0215 25 COG1309 AcrR, Transcriptional regulator Transcription 152998359 Common - hypothetical protein Mmwyl1_4364 5 None None None 152994617 Common - hypothetical protein Mmwyl1_0582 10 None None None 152996166 Nonpathogen - hypothetical protein Mmwyl1_2144 1 None None None 152994577 Common - phosphoribosyltransferase Mmwyl1_0541 110 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 152995820 Common - hypothetical protein Mmwyl1_1796 2 None None None 152995307 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mmwyl1_1278 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 152995239 Common - hypothetical protein Mmwyl1_1210 7 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 152997593 Common - porphobilinogen deaminase Mmwyl1_3591 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 152996012 Common - xylulokinase Mmwyl1_1989 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 152997666 Common - acriflavin resistance protein Mmwyl1_3665 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 152997210 Common - type III restriction protein res subunit Mmwyl1_3202 126 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 152997393 Common - transcriptional regulator, LysR family Mmwyl1_3390 182 COG0583 LysR, Transcriptional regulator Transcription 152994349 Common - response regulator receiver protein Mmwyl1_0308 25 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 152994884 Common - transport system permease protein Mmwyl1_0852 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 152997654 Common - Mg chelatase, subunit ChlI Mmwyl1_3653 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 152994159 Common - aldehyde dehydrogenase Mmwyl1_0117 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996060 Common - diguanylate phosphodiesterase Mmwyl1_2038 148 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152994164 Common - ABC transporter related Mmwyl1_0122 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 152997510 Common - inositol monophosphatase Mmwyl1_3507 168 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 152998014 Common - Glucose-6-phosphate isomerase Mmwyl1_4018 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 152994307 Common - transcriptional regulator, MarR family Mmwyl1_0265 13 COG1846 MarR, Transcriptional regulators Transcription 152994443 Common - transcriptional regulator, Fis family Mmwyl1_0405 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 152994834 Common - UDP-glucose/GDP-mannose dehydrogenase Mmwyl1_0800 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 152997320 Common - protein of unknown function DUF21 Mmwyl1_3315 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 152994232 Common - hypothetical protein Mmwyl1_0190 28 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 152997507 Common - Phosphoenolpyruvate carboxykinase (ATP) Mmwyl1_3504 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 152997923 Common - Carbamoyl-phosphate synthase L chain ATP-binding Mmwyl1_3926 236 COG0439 AccC, Biotin carboxylase Lipid metabolism 152995257 Common - hypothetical protein Mmwyl1_1228 28 None None None 152997161 Common - cytochrome d ubiquinol oxidase, subunit II Mmwyl1_3152 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 152995769 Nonpathogen - hypothetical protein Mmwyl1_1743 1 None None None 152994150 Common - alpha-2-macroglobulin domain protein Mmwyl1_0108 71 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 152995068 Common - glucokinase Mmwyl1_1037 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 152995942 Common - hypothetical protein Mmwyl1_1918 130 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 152997821 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3822 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152996059 Common - chaperonin GroEL Mmwyl1_2037 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 152994247 Common - helix-turn-helix- domain containing protein AraC type Mmwyl1_0205 80 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 152995531 Common - hypothetical protein Mmwyl1_1503 5 None None None 152995758 Common - TPR repeat-containing protein Mmwyl1_1732 57 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 152995195 Common - Lysine exporter protein (LYSE/YGGA) Mmwyl1_1166 112 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 152995209 Common - isocitrate lyase and phosphorylmutase Mmwyl1_1180 116 COG2224 AceA, Isocitrate lyase Energy production and conversion 152997717 Common - transcriptional regulator, LysR family Mmwyl1_3716 176 COG0583 LysR, Transcriptional regulator Transcription 152995899 Common - RbsD or FucU transport Mmwyl1_1875 30 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 152998027 Common - aldehyde dehydrogenase Mmwyl1_4031 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997519 Common - ABC transporter related Mmwyl1_3516 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 152995926 Common - diguanylate phosphodiesterase Mmwyl1_1902 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 152996360 Common - prolyl-tRNA synthetase Mmwyl1_2338 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152998304 Common - methyl-accepting chemotaxis sensory transducer Mmwyl1_4309 49 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 152994290 Common - MOFRL domain protein Mmwyl1_0248 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 152995444 Nonpathogen - Superoxide dismutase Ni-type Mmwyl1_1415 13 None None None 152998255 Common - ribosomal protein L18 Mmwyl1_4260 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 152997544 Common - CRISPR-associated protein Cas1 Mmwyl1_3541 46 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 152994628 Common - hypothetical protein Mmwyl1_0594 4 None None None 152996496 Common - choline/carnitine/betaine transporter Mmwyl1_2475 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 152994066 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_0023 189 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 152995218 Common - VgrG protein Mmwyl1_1189 15 None None None 152995656 Common - transport system permease protein Mmwyl1_1629 189 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 152994240 Common - DEAD/DEAH box helicase domain protein Mmwyl1_0198 242 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 152996367 Common - Sulfite reductase (ferredoxin) Mmwyl1_2345 170 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 152994648 Common - response regulator receiver protein Mmwyl1_0614 198 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 152995788 Common - transposase IS3/IS911 family protein Mmwyl1_1762 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 152994731 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mmwyl1_0697 47 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 152996866 Nonpathogen - hypothetical protein Mmwyl1_2854 1 None None None 152997586 Common - thioredoxin Mmwyl1_3584 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 152995683 Common - protein of unknown function DUF6 transmembrane Mmwyl1_1657 135 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152997216 Common - ABC transporter related Mmwyl1_3208 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152996560 Common - hypothetical protein Mmwyl1_2541 6 None None None 152997182 Common - 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase Mmwyl1_3174 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152997168 Common - Electron transfer flavoprotein alpha/beta-subunit Mmwyl1_3160 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 152998198 Nonpathogen - hypothetical protein Mmwyl1_4202 2 None None None 152994637 Nonpathogen - hypothetical protein Mmwyl1_0603 1 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 152996282 Common - acyl-CoA dehydrogenase domain protein Mmwyl1_2260 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 152994210 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0168 34 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 152995777 Common - Domain of unknown function DUF1853 Mmwyl1_1751 17 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 152997298 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mmwyl1_3293 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 152995620 Common - ABC transporter related Mmwyl1_1592 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 152997242 Common - hypothetical protein Mmwyl1_3236 4 None None None 152995844 Common - ABC transporter related Mmwyl1_1820 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 152995542 Common - hypothetical protein Mmwyl1_1514 3 None None None 152996674 Common - two component transcriptional regulator, winged helix family Mmwyl1_2661 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 152994096 Nonpathogen - hypothetical protein Mmwyl1_0054 1 None None None 152997644 Common - sulfatase Mmwyl1_3642 65 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 152998176 Common - putative acetyl-CoA C-acetyltransferase Mmwyl1_4180 89 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 152994129 Common - putative transcriptional regulator, GntR family Mmwyl1_0087 178 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 152996145 Common - phosphohistidine phosphatase, SixA Mmwyl1_2123 51 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 152995507 Common - transcriptional regulator, LysR family Mmwyl1_1478 96 COG0583 LysR, Transcriptional regulator Transcription 152996557 Common - transcriptional regulator, TetR family Mmwyl1_2538 18 COG1309 AcrR, Transcriptional regulator Transcription 152995371 Nonpathogen - hypothetical protein Mmwyl1_1342 2 None None None 152998081 Common - MltA domain protein Mmwyl1_4085 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 152996701 Common - CRISPR-associated RAMP protein, Cmr6 family Mmwyl1_2688 24 COG1604 COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 152995791 Common - TRAP transporter, 4TM/12TM fusion protein Mmwyl1_1765 116 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 152997083 Common - binding-protein-dependent transport systems inner membrane component Mmwyl1_3073 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 152997780 Nonpathogen - hypothetical protein Mmwyl1_3779 1 None None None 152996975 Nonpathogen - hypothetical protein Mmwyl1_2964 1 None None None 152997224 Common - sulfate transporter Mmwyl1_3218 136 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 152996142 Common - protein of unknown function UPF0061 Mmwyl1_2120 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 152996471 Common - TRAP dicarboxylate transporter, DctM subunit Mmwyl1_2449 136 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 152997115 Common - periplasmic binding protein/LacI transcriptional regulator Mmwyl1_3105 124 COG1609 PurR, Transcriptional regulators Transcription 152995095 Common - OsmC family protein Mmwyl1_1064 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 152994899 Common - sulfate transporter Mmwyl1_0867 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 152995439 Common - cobalamin-5-phosphate synthase CobS Mmwyl1_1410 128 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 152997171 Nonpathogen - hypothetical protein Mmwyl1_3163 1 COG4485 COG4485, Predicted membrane protein Function unknown 152998318 Common - glutathione synthetase Mmwyl1_4323 122 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 152996115 Common - 3-isopropylmalate dehydrogenase Mmwyl1_2093 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 152995419 Common - major facilitator superfamily MFS_1 Mmwyl1_1390 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152994871 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Mmwyl1_0839 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 152998031 Common - carbamoyl-phosphate synthase, small subunit Mmwyl1_4035 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 152995006 Common - isochorismatase hydrolase Mmwyl1_0975 91 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 152994454 Common - protein of unknown function DUF6 transmembrane Mmwyl1_0416 82 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 152996020 Common - protein of unknown function DUF125 transmembrane Mmwyl1_1998 86 COG1814 COG1814, Uncharacterized membrane protein Function unknown 152994434 Nonpathogen - hypothetical protein Mmwyl1_0396 2 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 152995972 Common - Endonuclease I Mmwyl1_1948 38 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 152994653 Common - orotate phosphoribosyltransferase Mmwyl1_0619 129 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 152996934 Common - dihydrodipicolinate synthase Mmwyl1_2923 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 152995976 Common - Haloacid dehalogenase domain protein hydrolase Mmwyl1_1952 3 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 152998429 Common - putative tricarboxylic transport membrane protein Mmwyl1_4434 19 None None None 152997569 Common - flagellar protein FliS Mmwyl1_3567 76 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 152994542 Common - aldehyde dehydrogenase Mmwyl1_0506 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 152996778 Common - ABC transporter related Mmwyl1_2765 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152994348 Common - pilus (Caulobacter type) biogenesis lipoprotein CpaD Mmwyl1_0307 2 COG5461 COG5461, Type IV pili component Cell motility and secretion 152998381 Common - (p)ppGpp synthetase I, SpoT/RelA Mmwyl1_4386 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 152995534 Common - cytochrome d ubiquinol oxidase, subunit II Mmwyl1_1506 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 152996753 Common - MscS Mechanosensitive ion channel Mmwyl1_2740 207 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 152995140 Common - acetylornithine and succinylornithine aminotransferase Mmwyl1_1109 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 152998225 Common - isoleucyl-tRNA synthetase Mmwyl1_4230 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 152997367 Common - Integrase catalytic region Mmwyl1_3363 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 152998058 Common - protein of unknown function DUF890 Mmwyl1_4062 28 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 152996833 Common - response regulator receiver and ANTAR domain protein Mmwyl1_2821 146 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 152998074 Common - phospholipid/glycerol acyltransferase Mmwyl1_4078 52 COG3176 COG3176, Putative hemolysin General function prediction only 152996692 Nonpathogen - hypothetical protein Mmwyl1_2679 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 152998073 Common - hypothetical protein Mmwyl1_4077 6 None None None 152994768 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Mmwyl1_0734 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 152997005 Common - putative alkylated DNA repair protein Mmwyl1_2994 41 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 152996857 Common - rare lipoprotein A Mmwyl1_2845 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 152996184 Common - D-cysteine desulfhydrase, PLP-dependent enzyme Mmwyl1_2162 58 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 152997325 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mmwyl1_3320 53 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 152995449 Common - GCN5-related N-acetyltransferase Mmwyl1_1420 32 COG0456 RimI, Acetyltransferases General function prediction only 152997548 Common - CRISPR-associated protein, Cse4 family Mmwyl1_3545 42 None None None 152998153 Common - cytochrome bd ubiquinol oxidase subunit I Mmwyl1_4157 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 152995890 Common - D-xylose ABC transporter, ATPase subunit Mmwyl1_1866 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism