Alkaliphilus metalliredigens QYMF, complete genome NC_009633 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 150388477 Common - TRAP transporter, 4TM/12TM fusion protein Amet_0642 109 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 150389500 Common - arginyl-tRNA synthetase Amet_1714 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150390515 Common - acyl carrier protein Amet_2754 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150388521 Common - hypothetical protein Amet_0686 6 None None None 150388029 Common - S-layer domain protein Amet_0182 21 None None None 150389913 Common - RNA polymerase, alpha subunit domain protein Amet_2144 33 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 150391080 Nonpathogen - hypothetical protein Amet_3342 3 None None None 150389290 Common - amidinotransferase Amet_1484 38 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 150389297 Common - protein of unknown function DUF405 Amet_1491 56 COG2311 COG2311, Predicted membrane protein Function unknown 150392176 Common - elongation factor Tu Amet_4494 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 150392169 Common - ribosomal protein L7/L12 Amet_4487 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 150388302 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Amet_0464 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 150388338 Common - Gluconate transporter Amet_0501 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 150388357 Nonpathogen - Membrane-bound metallopeptidase-like protein Amet_0520 1 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 150392004 Common - protein of unknown function DUF1576 Amet_4320 5 None None None 150390845 Common - NADH dehydrogenase (quinone) Amet_3095 184 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150389543 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_1761 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150390017 Nonpathogen - hypothetical protein Amet_2249 1 None None None 150389691 Common - two component transcriptional regulator, winged helix family Amet_1917 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391513 Common - mannonate dehydratase Amet_3784 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 150391917 Common - protein of unknown function DUF1657 Amet_4227 8 None None None 150392438 Common - Peptidase M1, membrane alanine aminopeptidase-like protein Amet_4762 129 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150389232 Common - pentapeptide repeat protein Amet_1422 45 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150392204 Common - hypothetical protein Amet_4522 12 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 150392297 Common - Leucyl aminopeptidase Amet_4616 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 150388250 Nonpathogen - hypothetical protein Amet_0412 1 None None None 150390658 Common - Propanediol utilization protein Amet_2898 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 150389489 Common - hypothetical protein Amet_1703 13 COG4997 COG4997, Uncharacterized conserved protein Function unknown 150390455 Common - protein of unknown function DUF342 Amet_2693 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 150389711 Nonpathogen - hypothetical protein Amet_1938 1 None None None 150391068 Common - binding-protein-dependent transport systems inner membrane component Amet_3330 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388544 Common - integral membrane sensor signal transduction histidine kinase Amet_0709 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390476 Common - MotA/TolQ/ExbB proton channel Amet_2714 106 COG1291 MotA, Flagellar motor component Cell motility and secretion 150388503 Common - hypothetical protein Amet_0668 3 None None None 150390512 Common - Radical SAM domain protein Amet_2751 115 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 150390649 Nonpathogen - hypothetical protein Amet_2889 1 None None None 150390794 Common - RNA modification enzyme, MiaB family Amet_3044 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150388863 Common - Abortive infection protein Amet_1036 22 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 150390351 Nonpathogen - hypothetical protein Amet_2589 1 None None None 150392160 Common - ribosomal protein L3 Amet_4478 243 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 150389594 Nonpathogen - hypothetical protein Amet_1814 1 None None None 150389863 Common - cobalamin B12-binding domain protein Amet_2093 166 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 150389153 Common - protein of unknown function DUF21 Amet_1343 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150389951 Common - Ion transport protein Amet_2182 109 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 150390183 Nonpathogen - hypothetical protein Amet_2419 2 None None None 150390251 Nonpathogen - hypothetical protein Amet_2488 1 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 150388679 Nonpathogen - hypothetical protein Amet_0844 1 None None None 150389623 Nonpathogen - hypothetical protein Amet_1843 1 None None None 150392093 Nonpathogen - hypothetical protein Amet_4410 4 None None None 150392379 Nonpathogen - hypothetical protein Amet_4701 1 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 150390509 Common - putative helix-turn-helix protein, YlxM/p13 family protein Amet_2748 27 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 150388622 Nonpathogen - hypothetical protein Amet_0787 5 None None None 150389705 Nonpathogen - hypothetical protein Amet_1932 1 None None None 150390884 Nonpathogen - hypothetical protein Amet_3135 2 None None None 150388988 Common - hypothetical protein Amet_1169 34 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 150389183 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1373 36 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150388788 Common - phosphodiesterase, MJ0936 family Amet_0958 65 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150391163 Common - hypothetical protein Amet_3425 5 None None None 150388511 Common - Gamma-glutamyltransferase Amet_0676 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 150389392 Nonpathogen - transposase IS3/IS911 Amet_1605 2 None None None 150387923 Common - cobalamin biosynthesis protein CbiD Amet_0070 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 150392148 Common - ribosomal protein L5 Amet_4466 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 150388383 Common - two component transcriptional regulator, winged helix family Amet_0546 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391719 Common - hypothetical protein Amet_4027 4 None None None 150390536 Common - thiamine pyrophosphokinase Amet_2776 51 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 150392300 Common - FMN-binding domain protein Amet_4619 12 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 150389524 Nonpathogen - hypothetical protein Amet_1739 1 None None None 150391212 Common - type IV pilus assembly protein PilM Amet_3474 69 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 150389522 Common - extracellular solute-binding protein, family 1 Amet_1736 107 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150388682 Common hsdR type I restriction enzyme EcoKI subunit R Amet_0847 119 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 150389700 Common - Uncharacterized ATPase putative transposase Amet_1927 15 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 150387962 Common - methionyl-tRNA synthetase Amet_0110 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150391904 Common - hypothetical protein Amet_4214 3 None None None 150390531 Common - ATP-dependent DNA helicase RecG Amet_2770 223 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 150390209 Common - Threonine aldolase Amet_2445 119 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 150391385 Common - manganese containing catalase Amet_3653 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 150391346 Common - putative L-threonine-O-3-phosphate decarboxylase Amet_3614 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150390785 Common - protein of unknown function DUF1429 Amet_3035 14 None None None 150390970 Common - Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Amet_3222 24 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 150388695 Common - hypothetical protein Amet_0860 6 None None None 150391478 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Amet_3749 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150391862 Common - S-layer domain protein Amet_4171 12 None None None 150390394 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Amet_2632 55 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 150391145 Common - aspartate kinase Amet_3407 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 150391818 Common - excinuclease ABC subunit B Amet_4127 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 150392267 Common - glutamate formiminotransferase Amet_4586 22 COG3643 COG3643, Glutamate formiminotransferase Amino acid transport and metabolism 150392354 Nonpathogen - hypothetical protein Amet_4676 1 None None None 150391774 Nonpathogen - copper amine oxidase domain protein Amet_4082 1 None None None 150390188 Common - hypothetical protein Amet_2424 4 None None None 150388780 Common - hypothetical protein Amet_0950 15 None None None 150391826 Common - Exopolysaccharide biosynthesis protein Amet_4135 23 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150387998 Common - Orn/Lys/Arg decarboxylase, major region Amet_0149 90 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 150388689 Nonpathogen - hypothetical protein Amet_0854 1 None None None 150389781 Common - ABC transporter related Amet_2008 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390009 Common - GCN5-related N-acetyltransferase Amet_2241 26 COG3981 COG3981, Predicted acetyltransferase General function prediction only 150389800 Common - bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta Amet_2028 19 COG1614 CdhC, CO dehydrogenase/acetyl-CoA synthase beta subunit Energy production and conversion 150389242 Common - YbaK/prolyl-tRNA synthetase associated region Amet_1433 29 COG2606 EbsC, Uncharacterized conserved protein Function unknown 150391156 Common - acetolactate synthase, large subunit, biosynthetic type Amet_3418 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150391860 Common - Recombination helicase AddA Amet_4169 229 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 150388832 Nonpathogen - hypothetical protein Amet_1005 1 None None None 150390833 Common - hypothetical protein Amet_3083 3 None None None 150391356 Common - hypothetical protein Amet_3624 8 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 150388943 Common - MATE efflux family protein Amet_1122 156 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150388107 Common - hypothetical protein Amet_0264 3 None None None 150391668 Nonpathogen - hypothetical protein Amet_3972 1 None None None 150390734 Common - hypothetical protein Amet_2975 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 150387978 Common - regulatory protein, ArsR Amet_0129 178 COG0640 ArsR, Predicted transcriptional regulators Transcription 150388947 Common - putative transcriptional regulator, Crp/Fnr family Amet_1126 91 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150388240 Nonpathogen - hypothetical protein Amet_0402 1 None None None 150389531 Nonpathogen - hypothetical protein Amet_1747 1 None None None 150390238 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Amet_2474 213 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150390675 Common - extracellular solute-binding protein, family 5 Amet_2915 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150389049 Common - redox-active disulfide protein 2 Amet_1231 67 None None None 150390572 Common - Monosaccharide-transporting ATPase Amet_2812 112 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 150391327 Common - thioredoxin reductase Amet_3595 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150391121 Common - N-acetyl-gamma-glutamyl-phosphate reductase Amet_3383 217 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 150391470 Nonpathogen - hypothetical protein Amet_3741 2 None None None 150388014 Nonpathogen - hypothetical protein Amet_0167 3 None None None 150389605 Nonpathogen - hypothetical protein Amet_1825 1 None None None 150391674 Nonpathogen - hypothetical protein Amet_3979 1 None None None 150388886 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Amet_1064 171 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150388463 Nonpathogen - hypothetical protein Amet_0627 1 None None None 150392465 Common - cysteine desulfurase family protein Amet_4789 245 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150389431 Common - ABC transporter related Amet_1644 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 150391568 Common - Choline/ethanolamine kinase Amet_3841 23 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 150388424 Common - ABC transporter related Amet_0587 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150392059 Common - Exopolysaccharide biosynthesis protein Amet_4375 16 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150392052 Nonpathogen - hypothetical protein Amet_4368 1 None None None 150390459 Common - putative CheW protein Amet_2697 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150388851 Common - ABC transporter related Amet_1024 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 150391128 Common aspC aspartyl-tRNA synthetase Amet_3390 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150389114 Common - hypothetical protein Amet_1299 9 None None None 150388082 Common - membrane protein-like protein Amet_0239 9 COG4640 COG4640, Predicted membrane protein Function unknown 150389985 Common - stage V sporulation protein AB Amet_2217 4 None None None 150391741 Common - virulence-associated E family protein Amet_4049 33 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 150387878 Nonpathogen - hypothetical protein Amet_0025 1 None None None 150389793 Common - hypothetical protein Amet_2021 16 None None None 150389145 Nonpathogen - hypothetical protein Amet_1333 2 None None None 150389032 Common - membrane-bound metal-dependent hydrolase Amet_1214 5 None None None 150388936 Nonpathogen - hypothetical protein Amet_1115 1 None None None 150390981 Nonpathogen - hypothetical protein Amet_3233 2 None None None 150389772 Common - GCN5-related N-acetyltransferase Amet_1999 6 None None None 150388204 Common - Sporulation stage III, transcriptional regulator SpoIIID Amet_0364 15 None None None 150391171 Nonpathogen - hypothetical protein Amet_3433 2 None None None 150392250 Common - aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead Amet_4569 115 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150392429 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Amet_4753 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 150391119 Common - acetylglutamate kinase Amet_3381 214 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 150390168 Nonpathogen - small acid-soluble spore protein, alpha/beta type Amet_2404 2 None None None 150390450 Common - translation elongation factor Ts Amet_2688 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 150388275 Common - hypothetical protein Amet_0437 4 None None None 150390633 Common - cell division protein FtsZ Amet_2873 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 150391572 Nonpathogen - hypothetical protein Amet_3845 1 None None None 150388825 Common - twin-arginine translocation protein, TatA/E family subunit Amet_0998 6 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 150388047 Common - Heparinase II/III family protein Amet_0202 45 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 150389005 Common - methyl-accepting chemotaxis sensory transducer Amet_1187 135 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150388220 Common - GntR domain protein Amet_0381 151 COG2186 FadR, Transcriptional regulators Transcription 150388763 Nonpathogen - hypothetical protein Amet_0933 1 None None None 150389132 Common - aconitate hydratase Amet_1320 223 COG1048 AcnA, Aconitase A Energy production and conversion 150389357 Common - transcriptional regulator, PadR-like family Amet_1565 62 COG1695 COG1695, Predicted transcriptional regulators Transcription 150388953 Common - binding-protein-dependent transport systems inner membrane component Amet_1132 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388180 Common - CMP/dCMP deaminase, zinc-binding Amet_0340 110 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 150388841 Common - two component transcriptional regulator, winged helix family Amet_1014 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150389461 Common - polar amino acid ABC transporter, inner membrane subunit Amet_1674 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150387954 Common - ABC transporter related Amet_0101 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390336 Nonpathogen - hypothetical protein Amet_2574 2 None None None 150388271 Common - hypothetical protein Amet_0433 16 None None None 150391434 Common - Na+/H+ antiporter NhaC Amet_3704 53 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 150392184 Common - serine O-acetyltransferase Amet_4502 216 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 150389839 Common - peptidase M55, D-aminopeptidase Amet_2068 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 150390304 Common - RNA chaperone Hfq Amet_2541 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 150390873 Common - dephospho-CoA kinase Amet_3124 211 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 150388366 Common - putative transmembrane protein Amet_0529 14 COG4758 COG4758, Predicted membrane protein Function unknown 150390296 Common - pyrroline-5-carboxylate reductase Amet_2533 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 150389167 Common - glycine dehydrogenase subunit 2 Amet_1357 174 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 150389485 Common - TraB family protein Amet_1699 39 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 150391329 Common - degV family protein Amet_3597 55 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150389514 Common - Methyltransferase type 11 Amet_1728 91 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150389966 Common - hypothetical protein Amet_2198 2 None None None 150392337 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Amet_4657 119 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150389559 Common - IS66 Orf2 family protein Amet_1777 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389822 Common - hypothetical protein Amet_2051 7 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 150392226 Common - tRNA(Ile)-lysidine synthetase Amet_4544 239 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 150391320 Common - basic membrane lipoprotein Amet_3588 94 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 150390810 Common - beta-lactamase domain protein Amet_3060 115 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 150391473 Common - D-alanine--D-alanine ligase domain protein Amet_3744 231 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150391198 Common - flavocytochrome c Amet_3460 219 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150388757 Nonpathogen - FAD dependent dehydrogenase Amet_0927 7 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 150390381 Common - putative transcriptional regulator, MerR family Amet_2619 4 COG0789 SoxR, Predicted transcriptional regulators Transcription 150391987 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Amet_4303 71 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 150389094 Common - hypothetical protein Amet_1279 13 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150391980 Nonpathogen - hypothetical protein Amet_4294 1 None None None 150390199 Nonpathogen - hypothetical protein Amet_2435 1 None None None 150389646 Nonpathogen - hypothetical protein Amet_1870 1 None None None 150389343 Common - putative transcriptional regulator, GntR family Amet_1547 222 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150390311 Common - Sporulation domain protein Amet_2548 11 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 150391278 Common - ATPase associated with various cellular activities, AAA_5 Amet_3542 38 COG0714 COG0714, MoxR-like ATPases General function prediction only 150388413 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Amet_0576 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 150388133 Nonpathogen - hypothetical protein Amet_0291 2 COG4305 COG4305, Endoglucanase C-terminal domain/subunit and related proteins Carbohydrate transport and metabolism 150388460 Nonpathogen - hypothetical protein Amet_0624 1 None None None 150391462 Nonpathogen - hypothetical protein Amet_3733 1 None None None 150390891 Common - histidine kinase Amet_3142 157 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150389944 Common - ABC transporter related Amet_2175 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150390719 Common garR tartronate semialdehyde reductase Amet_2959 193 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 150388976 Common - phosphonate metabolism PhnJ Amet_1155 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 150392121 Common - hypothetical protein Amet_4439 9 COG1950 COG1950, Predicted membrane protein Function unknown 150388697 Nonpathogen - hypothetical protein Amet_0862 2 None None None 150392474 Common - single-stranded nucleic acid binding R3H domain protein Amet_4798 71 COG1847 Jag, Predicted RNA-binding protein General function prediction only 150391023 Nonpathogen - hypothetical protein Amet_3276 2 None None None 150389884 Nonpathogen - hypothetical protein Amet_2115 1 None None None 150388447 Common - flagellar basal body-associated protein FliL Amet_0611 8 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 150388923 Nonpathogen - hypothetical protein Amet_1102 1 None None None 150390988 Common - BioY protein Amet_3240 75 COG1268 BioY, Uncharacterized conserved protein General function prediction only 150390260 Common - Sporulation stage III, protein AF Amet_2497 4 None None None 150392115 Common - PAS/PAC sensor signal transduction histidine kinase Amet_4433 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390498 Common - Mg chelatase, subunit ChlI Amet_2737 199 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 150387947 Common - putative nicotinate phosphoribosyltransferase Amet_0094 140 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 150391969 Common - GCN5-related N-acetyltransferase Amet_4282 20 COG0456 RimI, Acetyltransferases General function prediction only 150389999 Common - hypothetical protein Amet_2231 12 COG0730 COG0730, Predicted permeases General function prediction only 150390160 Nonpathogen - hypothetical protein Amet_2396 1 COG5532 COG5532, Uncharacterized conserved protein Function unknown 150392025 Nonpathogen - hypothetical protein Amet_4341 1 None None None 150390020 Common - GCN5-related N-acetyltransferase Amet_2252 3 COG0456 RimI, Acetyltransferases General function prediction only 150391550 Common - Propanediol utilization protein Amet_3823 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 150387933 Nonpathogen - hypothetical protein Amet_0080 1 None None None 150391998 Common - transport-associated protein Amet_4314 34 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 150391200 Common - protein of unknown function DUF520 Amet_3462 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 150390002 Common - NAD+ synthetase Amet_2234 218 COG0171 NadE, NAD synthase Coenzyme metabolism 150391607 Common - hypothetical protein Amet_3900 3 None None None 150392365 Nonpathogen - copper amine oxidase domain protein Amet_4687 9 None None None 150388485 Common - 3-dehydroquinate synthase Amet_0650 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 150390966 Nonpathogen - sodium pump decarboxylase, gamma subunit Amet_3218 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 150387869 Common - glycine dehydrogenase subunit 2 Amet_0016 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 150392236 Common - sigma54 specific transcriptional regulator, Fis family Amet_4554 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150390666 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2906 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390588 Common - major facilitator superfamily MFS_1 Amet_2828 174 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150390698 Common - beta-lactamase domain protein Amet_2938 72 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150388059 Common - integral membrane protein MviN Amet_0214 200 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 150389449 Common - CRISPR-associated helicase Cas3 Amet_1662 77 COG1203 COG1203, Predicted helicases General function prediction only 150389178 Common - Spore germination YpeB Amet_1368 14 None None None 150387940 Common - putative RNA polymerase sigma factor SigI Amet_0087 19 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150390388 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Amet_2626 178 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150391926 Common - thiamine biosynthesis protein ThiF Amet_4236 183 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 150390826 Common - spore germination protein Amet_3076 7 None None None 150389741 Nonpathogen - hypothetical protein Amet_1968 2 None None None 150390469 Common - flagellar biosynthetic protein FliP Amet_2707 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 150391844 Common - NADH-ubiquinone oxidoreductase, chain 4L Amet_4153 81 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 150389367 Common - protein of unknown function DUF81 Amet_1578 12 COG0730 COG0730, Predicted permeases General function prediction only 150390034 Nonpathogen - hypothetical protein Amet_2266 4 None None None 150391481 Common - protein of unknown function DUF1271 Amet_3752 29 COG3592 COG3592, Uncharacterized conserved protein Function unknown 150389629 Nonpathogen - hypothetical protein Amet_1849 1 None None None 150391702 Common - NUMOD4 domain protein Amet_4010 8 None None None 150388236 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Amet_0398 122 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150390109 Common - hypothetical protein Amet_2345 7 None None None 150391405 Common - fructose-1,6-bisphosphate aldolase, class II Amet_3675 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 150391783 Common - hypothetical protein Amet_4092 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 150388482 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Amet_0647 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 150389807 Common - extracellular solute-binding protein, family 5 Amet_2035 198 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150389229 Common - GCN5-related N-acetyltransferase Amet_1419 19 COG0456 RimI, Acetyltransferases General function prediction only 150390423 Common - tRNA 2-selenouridine synthase Amet_2661 66 COG2603 COG2603, Predicted ATPase General function prediction only 150391035 Common - binding-protein-dependent transport systems inner membrane component Amet_3294 141 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 150392417 Common - efflux transporter, RND family, MFP subunit Amet_4741 65 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150392432 Nonpathogen - hypothetical protein Amet_4756 1 None None None 150390866 Common - beta-lactamase domain protein Amet_3117 65 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 150389683 Nonpathogen - hypothetical protein Amet_1909 1 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 150390546 Common - peptide deformylase Amet_2786 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 150391318 Common - Radical SAM domain protein Amet_3586 101 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150388390 Common - transcriptional regulator, GntR family Amet_0553 137 COG1802 GntR, Transcriptional regulators Transcription 150390651 Common - peptidase M16 domain protein Amet_2891 157 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150390772 Common - glycyl-tRNA synthetase Amet_3022 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150391744 Common - Phage regulatory protein, Rha family Amet_4052 27 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 150389973 Common - aminotransferase, class V Amet_2205 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 150390626 Common - two component transcriptional regulator, winged helix family Amet_2866 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150390951 Common - spore germination B3 GerAC family protein Amet_3203 15 None None None 150388859 Common - ABC-type bacteriocin transporter Amet_1032 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 150388533 Common - amino acid permease-associated region Amet_0698 167 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150391238 Common - Mov34/MPN/PAD-1 family protein Amet_3500 47 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 150389245 Common - GCN5-related N-acetyltransferase Amet_1436 74 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150391302 Common smpB SsrA-binding protein Amet_3570 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 150389545 Common - conserved hypothetical membrane-spanning protein Amet_1763 2 None None None 150390243 Common - putative RNA polymerase, sigma 28 subunit, FliA/WhiG family Amet_2480 51 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150389455 Common - CRISPR-associated protein Cas2 Amet_1668 51 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150391410 Common - conserved hypothetical selenoprotein Amet_3680 11 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 150390131 Common - dihydrodipicolinate reductase Amet_2367 27 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 150390462 Common - type IV pilus assembly PilZ Amet_2700 14 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 150391249 Nonpathogen - hypothetical protein Amet_3512 1 None None None 150389856 Common - cobalamin B12-binding domain protein Amet_2086 166 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 150389757 Common - hypothetical protein Amet_1984 2 None None None 150390129 Common - Glycine hydroxymethyltransferase Amet_2365 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 150391556 Common - Ethanolamine utilization protein EutN/carboxysome structural protein Ccml Amet_3829 7 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150391650 Common - conserved hypothetical protein 1655 Amet_3952 4 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 150389088 Common - putative metal dependent hydrolase Amet_1272 7 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150389003 Common - glutaredoxin Amet_1185 42 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 150388443 Common - (2Fe-2S)-binding domain protein Amet_0606 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 150389439 Common - cobalt transport protein Amet_1652 10 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150388001 Common - purine operon repressor Amet_0154 106 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 150388032 Nonpathogen - hypothetical protein Amet_0185 1 None None None 150388132 Nonpathogen - hypothetical protein Amet_0290 1 None None None 150390723 Common - 3-isopropylmalate dehydratase Amet_2963 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 150390817 Nonpathogen - hypothetical protein Amet_3067 1 None None None 150389903 Nonpathogen - hypothetical protein Amet_2134 5 None None None 150388654 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Amet_0819 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150387876 Nonpathogen - hypothetical protein Amet_0023 1 None None None 150389634 Common - KWG Leptospira repeat protein Amet_1855 26 None None None 150388458 Common - RNA-directed DNA polymerase (Reverse transcriptase) Amet_0622 92 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150390071 Common - protein of unknown function DUF464 Amet_2304 20 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 150390257 Common - Stage III sporulation AC family protein Amet_2494 15 None None None 150388269 Nonpathogen - hypothetical protein Amet_0431 2 None None None 150391574 Common - ABC transporter related Amet_3847 247 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 150389445 Common - hypothetical protein Amet_1658 3 None None None 150389998 Common - CoA-binding domain protein Amet_2230 128 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 150389224 Common - Methyltransferase type 12 Amet_1414 36 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150391894 Common - ABC-2 type transporter Amet_4204 177 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 150390401 Nonpathogen - GCN5-related N-acetyltransferase Amet_2639 1 None None None 150392389 Common - protein of unknown function DUF395, YeeE/YedE Amet_4711 76 None None None 150388439 Common - integral membrane sensor signal transduction histidine kinase Amet_0602 190 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390048 Common - electron transport complex, RnfABCDGE type, D subunit Amet_2281 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 150391355 Common - Adenosylcobinamide-phosphate guanylyltransferase Amet_3623 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 150389018 Common - tryptophanyl-tRNA synthetase Amet_1200 234 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150390949 Common - spore germination protein Amet_3201 15 None None None 150388922 Common - YibE/F family protein Amet_1101 33 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150389029 Common - MATE efflux family protein Amet_1211 185 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150391259 Common - nitrogen regulatory protein P-II Amet_3522 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150389674 Common - hypothetical protein Amet_1900 30 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 150390958 Common - putative CoA-substrate-specific enzyme activase Amet_3210 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 150387951 Nonpathogen - Accessory gene regulator B Amet_0098 2 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150392400 Common - nickel ABC transporter, periplasmic nickel-binding protein Amet_4722 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150390541 Common - radical SAM enzyme, Cfr family Amet_2781 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 150388584 Nonpathogen - hypothetical protein Amet_0749 5 None None None 150392265 Common - dihydroorotase, multifunctional complex type Amet_4584 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150389192 Common - dipeptidase, putative Amet_1382 142 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 150391594 Common - methyl-accepting chemotaxis sensory transducer Amet_3881 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150388968 Common - Na+/H+ antiporter MnhB subunit-related protein Amet_1147 23 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 150390204 Common - DNA adenine methylase Amet_2440 101 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 150388120 Common - polysaccharide biosynthesis protein CapD Amet_0277 218 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150390770 Common - hypothetical protein Amet_3020 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 150390720 Common - methyl-accepting chemotaxis sensory transducer Amet_2960 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150389138 Common - phosphonate ABC transporter, ATPase subunit Amet_1326 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 150390045 Common - PHP C-terminal domain protein Amet_2278 26 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 150390755 Common - two component transcriptional regulator, winged helix family Amet_3001 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150389737 Common - hypothetical protein Amet_1964 5 None None None 150391606 Nonpathogen - hypothetical protein Amet_3899 1 None None None 150388961 Common - protein of unknown function DUF156 Amet_1140 86 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 150388869 Nonpathogen - hypothetical protein Amet_1044 1 None None None 150392336 Common - Patatin Amet_4656 82 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 150388614 Common - TRAP transporter solute receptor, TAXI family Amet_0779 85 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 150388657 Common - protein of unknown function DUF77 Amet_0822 48 COG0011 COG0011, Uncharacterized conserved protein Function unknown 150391396 Common - arginine degradation protein (gene RocB) Amet_3665 18 COG4187 RocB, Arginine degradation protein (predicted deacylase) Amino acid transport and metabolism 150388772 Common ligA NAD-dependent DNA ligase LigA Amet_0942 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 150390177 Common - phage prohead protease, HK97 family Amet_2413 19 COG3740 COG3740, Phage head maturation protease General function prediction only 150391890 Common - aspartate carbamoyltransferase Amet_4200 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 150390496 Common - DNA topoisomerase I Amet_2735 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150392411 Common - peptidase M56, BlaR1 Amet_4735 26 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 150389170 Common - metal-dependent protein-like protein Amet_1360 16 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 150391285 Common - protein of unknown function DUF214 Amet_3551 17 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 150389676 Common - Chloramphenicol O-acetyltransferase Amet_1902 145 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150392067 Nonpathogen - hypothetical protein Amet_4383 2 None None None 150388522 Common - FdrA family protein Amet_0687 153 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 150390561 Common - RNA-binding S4 domain protein Amet_2801 33 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 150389287 Common - ABC transporter related Amet_1481 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150390555 Common - Uracil phosphoribosyltransferase Amet_2795 117 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 150392071 Nonpathogen - hypothetical protein Amet_4387 1 None None None 150390012 Common - GCN5-related N-acetyltransferase Amet_2244 20 COG0456 RimI, Acetyltransferases General function prediction only 150391801 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Amet_4110 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150391435 Nonpathogen - hypothetical protein Amet_3705 8 COG1584 COG1584, Predicted membrane protein Function unknown 150387953 Common - hypothetical protein Amet_0100 4 COG4652 COG4652, Uncharacterized protein conserved in bacteria Function unknown 150388181 Common - glycosyl transferase, family 4 Amet_0341 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 150389762 Nonpathogen - hypothetical protein Amet_1989 1 None None None 150389051 Common - ApbE family lipoprotein Amet_1234 139 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150391429 Nonpathogen - hypothetical protein Amet_3699 9 None None None 150389717 Common - Exopolysaccharide biosynthesis protein Amet_1944 16 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150389618 Common - cysteine desulfurase family protein Amet_1838 242 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150391109 Common - ABC transporter related Amet_3371 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150392133 Common - 30S ribosomal protein S11 Amet_4451 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 150389853 Nonpathogen - hypothetical protein Amet_2083 1 None None None 150390128 Common - protein of unknown function DUF1212 Amet_2364 41 COG2966 COG2966, Uncharacterized conserved protein Function unknown 150392453 Common - sodium/hydrogen exchanger Amet_4777 145 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 150389043 Common - Na/Pi-cotransporter II-related protein Amet_1225 129 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 150387900 Common - UBA/THIF-type NAD/FAD binding protein Amet_0047 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 150390442 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Amet_2680 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 150390800 Common - heat-inducible transcription repressor HrcA Amet_3050 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 150388664 Nonpathogen - Propeptide, PepSY amd peptidase M4 Amet_0829 1 None None None 150390503 Common - ribosomal protein L19 Amet_2742 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 150389507 Nonpathogen - hypothetical protein Amet_1721 1 COG3393 COG3393, Predicted acetyltransferase General function prediction only 150389166 Common - glycine dehydrogenase subunit 1 Amet_1356 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 150391044 Common - TrkA-N domain protein Amet_3305 124 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 150389687 Common - transcriptional regulator, TetR family Amet_1913 50 COG1309 AcrR, Transcriptional regulator Transcription 150391426 Common - nitroreductase Amet_3696 50 COG0778 NfnB, Nitroreductase Energy production and conversion 150389065 Common - phosphomethylpyrimidine kinase Amet_1249 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 150388000 Common murC UDP-N-acetylmuramate--L-alanine ligase Amet_0153 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 150391735 Nonpathogen - hypothetical protein Amet_4043 3 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 150388705 Common - GerA spore germination protein Amet_0870 15 None None None 150389798 Common - acetyl-CoA decarbonylase/synthase complex subunit gamma Amet_2026 22 COG1456 CdhE, CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) Energy production and conversion 150388997 Common - Methyltransferase type 12 Amet_1179 51 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150391265 Nonpathogen - hypothetical protein Amet_3529 2 None None None 150390280 Common - hypothetical protein Amet_2517 8 None None None 150390221 Common - protein of unknown function UPF0118 Amet_2457 210 COG0628 PerM, Predicted permease General function prediction only 150388033 Common - hypothetical protein Amet_0186 14 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150390265 Common - O-sialoglycoprotein endopeptidase Amet_2502 247 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 150390366 Common - phage recombination protein Bet Amet_2604 6 None None None 150388897 Common - shikimate 5-dehydrogenase Amet_1075 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 150392277 Nonpathogen - hypothetical protein Amet_4596 2 None None None 150391515 Common - TRAP dicarboxylate transporter, DctM subunit Amet_3786 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150387889 Nonpathogen - hypothetical protein Amet_0036 1 None None None 150391444 Common - copper amine oxidase domain protein Amet_3714 26 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150392344 Common - protein of unknown function DUF458 Amet_4664 15 COG1978 COG1978, Uncharacterized protein conserved in bacteria Function unknown 150390830 Common - secretion protein HlyD family protein Amet_3080 21 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150388418 Nonpathogen - hypothetical protein Amet_0581 1 None None None 150389189 Common - hypothetical protein Amet_1379 6 None None None 150390580 Common - glycerophosphoryl diester phosphodiesterase Amet_2820 164 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 150388567 Common - flagellin domain protein Amet_0732 123 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 150389536 Common - transposase Amet_1753 6 None None None 150389622 Nonpathogen - hypothetical protein Amet_1842 1 None None None 150391456 Common - protein of unknown function DUF421 Amet_3726 63 COG2323 COG2323, Predicted membrane protein Function unknown 150391873 Common - glucosamine-6-phosphate isomerase Amet_4182 91 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 150388894 Common - ATP-dependent protease La Amet_1072 209 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 150389237 Common - helix-turn-helix- domain containing protein, AraC type Amet_1428 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150389075 Common - phosphoenolpyruvate-protein phosphotransferase Amet_1259 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 150390321 Common - Baseplate J family protein Amet_2559 30 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150387866 Common - protein of unknown function DUF988 Amet_0013 19 COG4708 COG4708, Predicted membrane protein Function unknown 150389655 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_1880 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 150391925 Common - thiazole biosynthesis family protein Amet_4235 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 150389415 Common - Hsp33 protein Amet_1628 97 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 150388726 Common - ABC transporter related Amet_0894 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 150388909 Common - BFD domain protein (2Fe-2S)-binding domain protein Amet_1087 4 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 150388842 Nonpathogen - hypothetical protein Amet_1015 1 None None None 150391679 Nonpathogen - hypothetical protein Amet_3986 1 None None None 150390730 Common - hypothetical protein Amet_2970 5 None None None 150389219 Common - hypothetical protein Amet_1409 37 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150389081 Nonpathogen - hypothetical protein Amet_1265 2 None None None 150389574 Nonpathogen - hypothetical protein Amet_1793 1 None None None 150391617 Common - IstB domain protein ATP-binding protein Amet_3911 77 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150388259 Common - hypothetical protein Amet_0421 2 None None None 150390696 Common - hypothetical protein Amet_2936 5 None None None 150388814 Common - arsenite-activated ATPase ArsA Amet_0987 94 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 150390839 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Amet_3089 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150391721 Common - peptidase S14, ClpP Amet_4029 73 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150388874 Nonpathogen - hypothetical protein Amet_1049 1 None None None 150391363 Common - efflux transporter, RND family, MFP subunit Amet_3631 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150391696 Common - helix-turn-helix domain protein Amet_4004 4 None None None 150391850 Common - cation antiporter Amet_4159 67 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 150390856 Common - DNA topoisomerase (ATP-hydrolyzing) Amet_3106 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 150389832 Common - extracellular solute-binding protein, family 5 Amet_2061 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150390703 Common - methyl-accepting chemotaxis sensory transducer Amet_2943 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150388341 Common - aminotransferase, class I and II Amet_0504 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150392108 Common - lipoate-protein ligase B Amet_4426 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 150390711 Common - hypothetical protein Amet_2951 4 None None None 150389410 Common - Abortive infection protein Amet_1623 39 None None None 150391420 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Amet_3690 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150390155 Nonpathogen - hypothetical protein Amet_2391 1 None None None 150388640 Common - ribosomal-protein-alanine acetyltransferase Amet_0805 166 COG0456 RimI, Acetyltransferases General function prediction only 150388324 Common - OmpA/MotB domain protein Amet_0487 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150391710 Nonpathogen - hypothetical protein Amet_4018 1 None None None 150391373 Common - nitroreductase Amet_3641 10 COG0778 NfnB, Nitroreductase Energy production and conversion 150390718 Common - citrate lyase ligase Amet_2958 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 150391758 Common - Stage II sporulation E family protein Amet_4066 12 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150387907 Nonpathogen - hypothetical protein Amet_0054 1 None None None 150388555 Nonpathogen - hypothetical protein Amet_0720 2 None None None 150390808 Common - ComEC/Rec2-related protein Amet_3058 156 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 150390361 Common - hypothetical protein Amet_2599 11 None None None 150391135 Common - Glutamate synthase (ferredoxin) Amet_3397 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 150391539 Common - hypothetical protein Amet_3811 4 COG5660 COG5660, Predicted integral membrane protein Function unknown 150391773 Common - Integrase, catalytic region Amet_4081 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150392348 Common - ABC-2 type transporter Amet_4668 63 None None None 150387897 Common - protein of unknown function DUF156 Amet_0044 53 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 150388781 Nonpathogen - hypothetical protein Amet_0951 1 None None None 150390370 Nonpathogen - hypothetical protein Amet_2608 1 None None None 150388216 Common - prevent-host-death family protein Amet_0377 7 None None None 150388714 Nonpathogen - hypothetical protein Amet_0882 1 None None None 150387856 Common - RNA-binding S4 domain protein Amet_0003 52 COG2501 COG2501, Uncharacterized conserved protein Function unknown 150390341 Common - hypothetical protein Amet_2579 14 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 150390039 Nonpathogen - hypothetical protein Amet_2271 1 None None None 150389789 Common - Cobyrinic acid a,c-diamide synthase Amet_2017 31 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 150392311 Common - acetyl-CoA acetyltransferase Amet_4630 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150388152 Common - acyltransferase 3 Amet_0311 21 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 150388435 Common - ABC transporter related Amet_0598 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390377 Nonpathogen - hypothetical protein Amet_2615 1 None None None 150390319 Nonpathogen - hypothetical protein Amet_2557 1 None None None 150391330 Common - tRNA/rRNA methyltransferase (SpoU) Amet_3598 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 150391692 Common - hypothetical protein Amet_4000 20 None None None 150390610 Nonpathogen - hypothetical protein Amet_2850 3 None None None 150392405 Common - putative transcriptional regulator, GntR family Amet_4727 209 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150388199 Common - Sporulation stage II, protein D firmicutes Amet_0359 42 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 150391648 Common - hypothetical protein Amet_3947 19 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 150389263 Nonpathogen - hypothetical protein Amet_1454 1 None None None 150389083 Common - protein of unknown function DUF112, transmembrane Amet_1267 79 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 150390111 Common - carbonic anhydrase/acetyltransferase, isoleucine patch superfamily Amet_2347 215 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 150388309 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Amet_0472 121 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150391598 Common - major facilitator superfamily MFS_1 Amet_3887 119 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 150391638 Common - daunorubicin resistance ABC transporter ATPase subunit Amet_3937 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150389814 Common - Lytic transglycosylase, catalytic Amet_2042 168 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150391494 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_3765 169 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 150390056 Common - DNA repair protein RadC Amet_2289 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 150391104 Common - GCN5-related N-acetyltransferase Amet_3366 147 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150389206 Nonpathogen - hypothetical protein Amet_1396 1 None None None 150392452 Common - PhoH family protein Amet_4776 192 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 150391557 Common - microcompartments protein Amet_3830 7 None None None 150390428 Common - polysaccharide deacetylase Amet_2666 119 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150388560 Common - Anti-sigma-28 factor, FlgM family protein Amet_0725 10 None None None 150389037 Nonpathogen - hypothetical protein Amet_1219 4 None None None 150389599 Nonpathogen - hypothetical protein Amet_1819 1 None None None 150392138 Common - methionine aminopeptidase, type I Amet_4456 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 150388585 Common - Rubrerythrin Amet_0750 26 COG1592 COG1592, Rubrerythrin Energy production and conversion 150392037 Nonpathogen - hypothetical protein Amet_4353 1 None None None 150390575 Common - Monosaccharide-transporting ATPase Amet_2815 97 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 150389922 Nonpathogen - hypothetical protein Amet_2153 11 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 150392357 Nonpathogen - hypothetical protein Amet_4679 1 None None None 150390086 Common - Serine-type D-Ala-D-Ala carboxypeptidase Amet_2319 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150390681 Common - amine oxidase Amet_2921 30 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 150392290 Common - Arginine deiminase Amet_4609 60 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 150388173 Common - FHA domain containing protein Amet_0333 69 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 150389779 Common - binding-protein-dependent transport systems inner membrane component Amet_2006 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150387916 Common - glutamate-1-semialdehyde-2,1-aminomutase Amet_0063 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 150390634 Common - protein of unknown function DUF1290 Amet_2874 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 150390677 Nonpathogen - hypothetical protein Amet_2917 1 None None None 150391313 Common - transcriptional regulator, DeoR family Amet_3581 42 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 150388853 Common - CBS domain containing protein Amet_1026 5 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 150388599 Common - D-lactate dehydrogenase (cytochrome) Amet_0764 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150388636 Nonpathogen - hypothetical protein Amet_0801 1 None None None 150390220 Nonpathogen - hypothetical protein Amet_2456 1 None None None 150389372 Common - pentapeptide repeat protein Amet_1583 30 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150389022 Nonpathogen - hypothetical protein Amet_1204 1 None None None 150389286 Common - arsenite-activated ATPase ArsA Amet_1480 91 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 150392155 Common - ribosomal protein L22 Amet_4473 232 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 150392444 Common - replicative DNA helicase Amet_4768 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 150388097 Common - reactivating factor for ethanolamine ammonia lyase Amet_0254 17 COG4819 EutA, Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition Amino acid transport and metabolism 150390216 Common - transcriptional regulator, BadM/Rrf2 family Amet_2452 178 COG1959 COG1959, Predicted transcriptional regulator Transcription 150388981 Common - phosphonate ABC transporter, inner membrane subunit Amet_1161 85 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 150390473 Common - flagellar motor switch protein FliM Amet_2711 110 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 150388161 Common glpX fructose 1,6-bisphosphatase II Amet_0321 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 150391514 Nonpathogen - hypothetical protein Amet_3785 2 None None None 150392044 Common - hypothetical protein Amet_4360 2 None None None 150390729 Common - diguanylate phosphodiesterase Amet_2969 56 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 150391192 Common - degV family protein Amet_3454 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150388663 Common - PTS system, fructose subfamily, IIC subunit Amet_0828 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 150390939 Common - response regulator receiver protein Amet_3191 8 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 150389565 Common - ribosomal RNA adenine dimethylase Amet_1783 40 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 150390287 Common - phosphopentomutase Amet_2524 72 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 150389869 Common - ferredoxin Amet_2099 36 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 150388775 Common - Rubrerythrin Amet_0945 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 150389430 Common - iron dependent repressor Amet_1643 94 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 150391091 Nonpathogen - hypothetical protein Amet_3353 1 None None None 150391508 Common - SecA DEAD domain protein Amet_3779 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 150391505 Common - S-adenosyl-methyltransferase MraW Amet_3776 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 150391767 Common - deoxyguanosine kinase Amet_4075 40 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 150390432 Common - tRNA pseudouridine synthase B Amet_2670 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 150391450 Common - C_GCAxxG_C_C family protein Amet_3720 12 None None None 150389402 Common - Na+/Pi-cotransporter Amet_1615 88 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 150387976 Common - protein of unknown function DUF1568 Amet_0127 52 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389291 Nonpathogen - hypothetical protein Amet_1485 1 None None None 150391112 Common - Vitamin B12 dependent methionine synthase, activation region Amet_3374 14 None None None 150388301 Common - metal-dependent protein hydrolase Amet_0463 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 150391253 Common - ferredoxin, 2Fe-2S Amet_3516 98 COG3411 COG3411, Ferredoxin Energy production and conversion 150389730 Common - hypothetical protein Amet_1957 11 COG4834 COG4834, Uncharacterized protein conserved in bacteria Function unknown 150391088 Common - DEAD/DEAH box helicase domain protein Amet_3350 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150391336 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Amet_3604 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150390240 Nonpathogen - hypothetical protein Amet_2476 1 None None None 150391244 Nonpathogen - hypothetical protein Amet_3507 2 None None None 150390094 Common - hypothetical protein Amet_2327 11 COG5401 COG5401, Spore germination protein General function prediction only 150388377 Common - Pyridoxal-5'-phosphate-dependent protein, beta subunit Amet_0540 200 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 150389608 Common - arsenical-resistance protein Amet_1828 136 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 150390648 Common - MraZ protein Amet_2888 141 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 150390190 Common - hypothetical protein Amet_2426 6 None None None 150388710 Nonpathogen - hypothetical protein Amet_0878 1 None None None 150388793 Common - transposase, IS605 OrfB family Amet_0966 71 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 150391667 Common - IstB domain protein ATP-binding protein Amet_3971 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150389484 Common - GCN5-related N-acetyltransferase Amet_1698 97 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 150392372 Nonpathogen - hypothetical protein Amet_4694 1 None None None 150391857 Common - CBS domain containing protein Amet_4166 100 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 150391384 Common - NAD(P)H dehydrogenase (quinone) Amet_3652 56 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 150392327 Common - Nitrate reductase Amet_4646 186 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 150387882 Common - MscS Mechanosensitive ion channel Amet_0029 201 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150389450 Common - CRISPR-associated protein Cas5 family Amet_1663 31 None None None 150390945 Common - dihydrodipicolinate synthase Amet_3197 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150389316 Common - extracellular solute-binding protein, family 5 Amet_1512 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150390749 Common - protein of unknown function DUF188 Amet_2995 98 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 150390537 Common - Ribulose-phosphate 3-epimerase Amet_2777 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150392318 Nonpathogen - hypothetical protein Amet_4637 1 None None None 150391546 Common - Helix-turn-helix, type 11 domain protein Amet_3818 61 COG2378 COG2378, Predicted transcriptional regulator Transcription 150389179 Common - hypothetical protein Amet_1369 6 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150388604 Common - GCN5-related N-acetyltransferase Amet_0769 25 COG0456 RimI, Acetyltransferases General function prediction only 150390145 Common - hypothetical protein Amet_2381 3 None None None 150389921 Common - MukB N-terminal domain/M protein repeat protein Amet_2152 88 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 150389939 Common - band 7 protein Amet_2170 47 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 150391140 Common - ketol-acid reductoisomerase Amet_3402 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 150389154 Nonpathogen - hypothetical protein Amet_1344 1 None None None 150391223 Common - Radical SAM domain protein Amet_3485 90 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150390146 Common - AAA ATPase, central domain protein Amet_2382 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 150391561 Common - microcompartments protein Amet_3834 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 150390080 Common - iojap-like protein Amet_2313 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 150389280 Common - IstB domain protein ATP-binding protein Amet_1472 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150392157 Common rplB 50S ribosomal protein L2 Amet_4475 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 150387963 Common - hydrolase, TatD family Amet_0111 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 150388318 Common - protein of unknown function DUF111 Amet_0481 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 150391949 Common - hypothetical protein Amet_4261 26 None None None 150392361 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_4683 157 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150391830 Common - glycosyl transferase, WecB/TagA/CpsF family Amet_4139 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 150389221 Common - Group II intron, maturase-specific domain protein Amet_1411 80 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150390389 Common - cytidylate kinase Amet_2627 206 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 150392418 Common - binding-protein-dependent transport systems inner membrane component Amet_4742 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150391615 Common - transcriptional regulator, MarR family Amet_3909 40 COG1846 MarR, Transcriptional regulators Transcription 150390805 Common - germination protease Amet_3055 15 None None None 150390210 Common - recombination factor protein RarA Amet_2446 244 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 150392132 Common - ribosomal protein S4 Amet_4450 246 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 150390083 Common - putative endoribonuclease L-PSP Amet_2316 194 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 150390189 Common - hypothetical protein Amet_2425 16 COG5412 COG5412, Phage-related protein Function unknown 150390495 Common - transcriptional repressor CodY Amet_2734 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 150388900 Common - glutamine amidotransferase of anthranilate synthase Amet_1078 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 150391861 Nonpathogen - hypothetical protein Amet_4170 1 None None None 150389334 Common - cell wall/surface repeat protein Amet_1534 55 None None None 150391479 Common - GntR domain protein Amet_3750 145 COG2186 FadR, Transcriptional regulators Transcription 150391103 Common - death-on-curing family protein Amet_3365 60 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 150389060 Common - MgtC/SapB transporter Amet_1243 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 150387915 Common - delta-aminolevulinic acid dehydratase Amet_0062 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 150391447 Nonpathogen - ABC-2 type transporter Amet_3717 3 COG1511 COG1511, Predicted membrane protein Function unknown 150387999 Common - cell envelope-related transcriptional attenuator Amet_0152 61 COG1316 LytR, Transcriptional regulator Transcription 150388172 Common - zinc/iron permease Amet_0332 126 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 150389645 Common - Excinuclease ABC, C subunit domain protein Amet_1869 41 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 150391825 Common - Peptidoglycan-binding LysM Amet_4134 91 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 150391127 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Amet_3389 35 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 150388688 Common - hypothetical protein Amet_0853 16 None None None 150388887 Common - Alanine racemase Amet_1065 131 COG1609 PurR, Transcriptional regulators Transcription 150391155 Common - regulatory protein GntR, HTH Amet_3417 152 COG1725 COG1725, Predicted transcriptional regulators Transcription 150388613 Nonpathogen - hypothetical protein Amet_0778 1 None None None 150389351 Common - two-component sensor histidine kinase Amet_1557 5 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150390552 Common - domain of unknown function DUF1732 Amet_2792 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 150388774 Common - integral membrane protein TIGR01906 Amet_0944 6 COG4478 COG4478, Predicted membrane protein Function unknown 150391094 Common - YcfA family protein Amet_3356 14 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 150390827 Common - Membrane dipeptidase Amet_3077 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 150391471 Common - hypothetical protein Amet_3742 16 COG4843 COG4843, Uncharacterized protein conserved in bacteria Function unknown 150391492 Common - Cobyrinic acid a,c-diamide synthase Amet_3763 31 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 150388125 Common - acriflavin resistance protein Amet_0283 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150389400 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1613 108 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150390252 Common - peptidase M24 Amet_2489 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150391982 Common - putative restriction endonuclease Amet_4297 22 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 150390605 Common - IstB domain protein ATP-binding protein Amet_2845 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150388694 Nonpathogen - hypothetical protein Amet_0859 1 None None None 150391386 Common - spore coat peptide assembly protein cotJB Amet_3654 9 None None None 150390832 Common - protein of unknown function DUF112, transmembrane Amet_3082 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 150389486 Common - Quinone oxidoreductase putative, YhdH/YhfP Amet_1700 127 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 150389146 Common - HI0933 family protein Amet_1334 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 150388274 Common - hypothetical protein Amet_0436 27 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150389241 Common - protein of unknown function DUF1200 Amet_1432 6 None None None 150388499 Common - Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Amet_0664 74 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150390244 Common - hypothetical protein Amet_2481 8 None None None 150389432 Common - ABC-3 protein Amet_1645 192 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 150391326 Common - Thioredoxin domain Amet_3594 225 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150388948 Common - putative CoA-substrate-specific enzyme activase Amet_1127 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 150391845 Common - Na+/H+ antiporter MnhB subunit-related protein Amet_4154 5 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 150392210 Common - pantothenate kinase Amet_4528 131 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 150390050 Common - electron transport complex, RnfABCDGE type, E subunit Amet_2283 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 150391120 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Amet_3382 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 150390306 Common - DNA mismatch repair protein MutL Amet_2543 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 150387884 Common - putative transcriptional regulator, GntR family Amet_0031 226 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150389710 Nonpathogen - hypothetical protein Amet_1937 2 None None None 150390475 Common - OmpA/MotB domain protein Amet_2713 150 COG1360 MotB, Flagellar motor protein Cell motility and secretion 150392016 Common - Heptaprenyl diphosphate synthase component I Amet_4332 24 COG4769 COG4769, Predicted membrane protein Function unknown 150388899 Common - anthranilate synthase component I Amet_1077 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 150392355 Nonpathogen - hypothetical protein Amet_4677 3 None None None 150391328 Common - GrdX protein Amet_3596 6 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 150392094 Common - integral membrane sensor signal transduction histidine kinase Amet_4411 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150392114 Common - transcriptional regulator, LysR family Amet_4432 191 COG0583 LysR, Transcriptional regulator Transcription 150389749 Nonpathogen - hypothetical protein Amet_1976 1 None None None 150390235 Common - peptidase U32 Amet_2471 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150391172 Nonpathogen - hypothetical protein Amet_3434 5 None None None 150389105 Common - TRAP dicarboxylate transporter, DctM subunit Amet_1290 133 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150391817 Common - excinuclease ABC, A subunit Amet_4126 232 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 150388933 Nonpathogen - hypothetical protein Amet_1112 1 None None None 150388071 Common - type III effector Hrp-dependent outers Amet_0226 60 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 150388396 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_0559 48 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150391868 Common - putative metal dependent phosphohydrolase Amet_4177 71 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150389133 Common aksA trans-homoaconitate synthase Amet_1321 195 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150390191 Common - hypothetical protein Amet_2427 5 None None None 150388862 Common - Abortive infection protein Amet_1035 36 None None None 150392308 Common - ABC transporter related Amet_4627 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 150389585 Nonpathogen - hypothetical protein Amet_1805 1 None None None 150389391 Common - integrase, catalytic region Amet_1604 131 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389366 Nonpathogen - hypothetical protein Amet_1577 1 None None None 150392296 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Amet_4615 231 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150391017 Common - hypothetical protein Amet_3269 15 COG3462 COG3462, Predicted membrane protein Function unknown 150388256 Common - hypothetical protein Amet_0418 14 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 150389217 Nonpathogen - hypothetical protein Amet_1407 1 None None None 150388658 Common - ABC transporter related Amet_0823 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150388384 Common - integral membrane sensor signal transduction histidine kinase Amet_0547 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150389815 Nonpathogen - hypothetical protein Amet_2044 3 None None None 150391372 Common - regulatory protein, ArsR Amet_3640 10 COG4189 COG4189, Predicted transcriptional regulator Transcription 150391441 Common - integral membrane sensor signal transduction histidine kinase Amet_3711 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150388251 Common - hypothetical protein Amet_0413 10 None None None 150391251 Common - methylated-DNA--protein-cysteine methyltransferase Amet_3514 211 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 150389609 Common - Arsenical resistance operon trans-acting repressor ArsD Amet_1829 31 None None None 150390360 Common - protein of unknown function DUF1064 Amet_2598 11 None None None 150392378 Nonpathogen - hypothetical protein Amet_4700 1 None None None 150391597 Common - hypothetical protein Amet_3885 9 None None None 150388476 Common - hydrogenase, Fe-only Amet_0641 182 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150391005 Common - hypothetical protein Amet_3257 8 None None None 150390657 Common - deoxyribose-phosphate aldolase Amet_2897 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 150391956 Common - 1-phosphofructokinase Amet_4268 124 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 150390152 Nonpathogen - hypothetical protein Amet_2388 2 None None None 150391162 Common - hypothetical protein Amet_3424 6 None None None 150388579 Common - hypothetical protein Amet_0744 5 None None None 150389899 Common - GCN5-related N-acetyltransferase Amet_2130 24 COG0456 RimI, Acetyltransferases General function prediction only 150388918 Nonpathogen - hypothetical protein Amet_1096 1 None None None 150389808 Common - binding-protein-dependent transport systems inner membrane component Amet_2036 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388462 Nonpathogen - hypothetical protein Amet_0626 3 None None None 150390865 Common - Glycine hydroxymethyltransferase Amet_3116 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 150392203 Common - hypothetical protein Amet_4521 19 COG1306 COG1306, Uncharacterized conserved protein Function unknown 150389328 Common - permease, major facilitator superfamily Amet_1526 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150387870 Common - quinolinate synthetase complex, A subunit Amet_0017 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 150389523 Common - polynucleotide phosphorylase/polyadenylase Amet_1737 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 150388987 Common - phospholipase D/Transphosphatidylase Amet_1168 155 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 150391799 Common - NADH dehydrogenase (quinone) Amet_4108 192 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150390947 Common - cell wall hydrolase, SleB Amet_3199 36 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 150392227 Common - protein kinase Amet_4545 65 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 150389950 Common - RelA/SpoT domain protein Amet_2181 82 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 150389525 Nonpathogen - hypothetical protein Amet_1740 1 None None None 150389542 Common - Methyltransferase type 11 Amet_1760 95 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150388211 Common - Rod binding protein-like protein Amet_0371 39 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 150390513 Common - Ribonuclease III Amet_2752 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 150392026 Nonpathogen - hypothetical protein Amet_4342 1 None None None 150390773 Common - ubiquitin-associated- domain-containing protein Amet_3023 6 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 150389829 Common - Lytic transglycosylase, catalytic Amet_2058 170 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150391169 Nonpathogen - hypothetical protein Amet_3431 2 None None None 150391941 Common - peptidase M29, aminopeptidase II Amet_4253 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 150389128 Common - hypothetical protein Amet_1315 82 None None None 150391734 Common - HNH endonuclease Amet_4042 35 COG1403 McrA, Restriction endonuclease Defense mechanisms 150389501 Common - methyl-accepting chemotaxis sensory transducer Amet_1715 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150388315 Common - putative transcriptional regulator, MerR family Amet_0478 21 COG0789 SoxR, Predicted transcriptional regulators Transcription 150389918 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_2149 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150390592 Nonpathogen - hypothetical protein Amet_2832 4 None None None 150388631 Nonpathogen - Flagellin-specific chaperone FliS-like protein Amet_0796 2 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 150392065 Nonpathogen - hypothetical protein Amet_4381 1 None None None 150388134 Nonpathogen - hypothetical protein Amet_0292 3 None None None 150389632 Nonpathogen - hypothetical protein Amet_1853 1 None None None 150389298 Common - hypothetical protein Amet_1492 10 None None None 150388017 Common - Spore cortex biosynthesis protein YabQ Amet_0170 9 None None None 150390077 Common - metal dependent phosphohydrolase Amet_2310 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 150388237 Nonpathogen - hypothetical protein Amet_0399 2 None None None 150388520 Common - transcriptional regulator, PucR family Amet_0685 41 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 150389182 Common - transposase, IS4 family protein Amet_1372 17 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 150388975 Common - phosphonate metabolism Amet_1154 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 150391720 Common - phage major capsid protein, HK97 family Amet_4028 63 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 150389508 Common - Radical SAM domain protein Amet_1722 106 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150391905 Common - peptidase M55, D-aminopeptidase Amet_4215 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 150388512 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Amet_0677 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 150390539 Common - protein kinase Amet_2779 161 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 150390617 Common - small GTP-binding protein Amet_2857 235 COG1160 COG1160, Predicted GTPases General function prediction only 150389982 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Amet_2214 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150390967 Common - carboxyl transferase Amet_3219 211 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 150390001 Common - cysteine synthase A Amet_2233 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150387948 Common - nucleoside recognition domain protein Amet_0095 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 150388754 Common - phosphoribosylglycinamide formyltransferase Amet_0924 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 150390424 Common - cell division protein FtsK/SpoIIIE Amet_2662 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 150389054 Common - Di-trans-poly-cis-decaprenylcistransferase Amet_1237 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 150389624 Nonpathogen - hypothetical protein Amet_1844 1 None None None 150388980 Common - phosphonate ABC transporter, inner membrane subunit Amet_1160 127 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 150390980 Common - integral membrane sensor signal transduction histidine kinase Amet_3232 141 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 150391099 Common - hypothetical protein Amet_3361 35 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150391833 Nonpathogen - hypothetical protein Amet_4142 5 None None None 150391211 Common - Fimbrial assembly family protein Amet_3473 3 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 150390697 Common - putative ammonia monooxygenase Amet_2937 44 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 150390818 Nonpathogen - hypothetical protein Amet_3068 2 None None None 150391113 Common - Methylenetetrahydrofolate reductase (NAD(P)H) Amet_3375 169 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 150390421 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Amet_2659 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 150387924 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Amet_0071 98 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 150388083 Common - hypothetical protein Amet_0240 3 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 150390482 Nonpathogen - hypothetical protein Amet_2720 1 None None None 150391749 Common - restriction modification system DNA specificity domain Amet_4057 58 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 150387929 Common - precorrin-3B C17-methyltransferase Amet_0076 169 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 150391703 Common - hypothetical protein Amet_4011 14 None None None 150389378 Common - chromate transporter, chromate ion transporter (CHR) family Amet_1589 101 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 150389912 Common - hypothetical protein Amet_2143 30 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 150390489 Common - flagellar basal-body rod protein FlgC Amet_2727 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 150392258 Common - microcompartments protein Amet_4577 28 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150388621 Common - flagellar protein FliS Amet_0786 89 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 150390033 Nonpathogen - hypothetical protein Amet_2265 1 None None None 150390909 Common - ABC transporter related Amet_3160 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150391186 Common - YheD Amet_3448 6 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 150390924 Common - sodium:dicarboxylate symporter Amet_3175 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 150387868 Common - Glycine dehydrogenase (decarboxylating) Amet_0015 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 150389361 Nonpathogen - hypothetical protein Amet_1571 1 None None None 150389203 Common - hypothetical protein Amet_1393 8 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150391784 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Amet_4093 203 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 150388484 Common - chorismate synthase Amet_0649 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 150389769 Common - hypothetical protein Amet_1996 12 COG5036 COG5036, SPX domain-containing protein involved in vacuolar polyphosphate accumulation Inorganic ion transport and metabolism 150388719 Nonpathogen - hypothetical protein Amet_0887 1 None None None 150391743 Nonpathogen - hypothetical protein Amet_4051 2 None None None 150389864 Common - Na+/melibiose symporter and related transporter-like protein Amet_2094 76 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150389661 Common - N-acetylmuramoyl-L-alanine amidase Amet_1886 184 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150392237 Common - putative RNA methylase Amet_4555 135 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 150391319 Common - hypothetical protein Amet_3587 14 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150391995 Common - sigma54 specific transcriptional regulator, Fis family Amet_4311 180 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150388907 Common - aminopeptidase Amet_1085 61 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 150390527 Common - H+-ATPase subunit H Amet_2766 34 None None None 150389177 Common - Spore cortex-lytic enzyme SleB Amet_1367 40 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 150389972 Common - protein of unknown function DUF1121 Amet_2204 20 None None None 150388114 Common - 67 kDa myosin-cross-reactive antigen family protein Amet_0271 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 150388270 Common - hypothetical protein Amet_0432 2 None None None 150390650 Common - prolipoprotein diacylglyceryl transferase Amet_2890 191 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150388534 Common - Aldehyde ferredoxin oxidoreductase Amet_0699 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 150390768 Common - transcriptional regulator, PadR-like family Amet_3018 62 COG1695 COG1695, Predicted transcriptional regulators Transcription 150388347 Common - 4-aminobutyrate aminotransferase Amet_0510 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 150391603 Common - ABC transporter related Amet_3894 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 150389591 Nonpathogen - hypothetical protein Amet_1811 1 None None None 150390717 Common - initiator RepB protein Amet_2957 26 COG5527 COG5527, Protein involved in initiation of plasmid replication DNA replication, recombination, and repair 150391292 Common - IstB domain protein ATP-binding protein Amet_3560 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150388858 Nonpathogen - hypothetical protein Amet_1031 2 None None None 150388335 Common - multi antimicrobial extrusion protein MatE Amet_0498 123 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150391237 Common - Sulfite reductase (ferredoxin) Amet_3499 168 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 150390303 Common - AAA ATPase, central domain protein Amet_2540 64 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 150389246 Nonpathogen - hypothetical protein Amet_1437 1 None None None 150389544 Nonpathogen - hypothetical protein Amet_1762 1 None None None 150390382 Common - Cellulase Amet_2620 83 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 150391486 Common - translation initiation factor IF-2B subunit alpha Amet_3757 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 150391575 Nonpathogen - hypothetical protein Amet_3850 3 None None None 150391404 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Amet_3674 152 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 150389580 Nonpathogen - hypothetical protein Amet_1800 1 None None None 150389855 Common - methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase Amet_2085 161 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150391804 Common - dihydroxyacetone kinase, L subunit Amet_4113 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 150392364 Nonpathogen - hypothetical protein Amet_4686 1 None None None 150388442 Common - molybdopterin dehydrogenase, FAD-binding Amet_0605 15 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 150389759 Common - Formate C-acetyltransferase Amet_1986 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150387936 Common - protein of unknown function DUF970 Amet_0083 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 150388035 Common - acriflavin resistance protein Amet_0188 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150389758 Common - Cupin 2, conserved barrel domain protein Amet_1985 28 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150389692 Common - integral membrane sensor signal transduction histidine kinase Amet_1918 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150389639 Nonpathogen - hypothetical protein Amet_1860 1 None None None 150389656 Common - extracellular solute-binding protein, family 5 Amet_1881 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150389446 Common - nitroreductase Amet_1659 76 COG0778 NfnB, Nitroreductase Energy production and conversion 150390722 Common - 3-isopropylmalate dehydratase, small subunit Amet_2962 213 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 150390169 Common - putative sigma factor Amet_2405 4 None None None 150391779 Common - protein of unknown function DUF199 Amet_4088 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 150391975 Nonpathogen - hypothetical protein Amet_4289 1 None None None 150390516 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Amet_2755 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150388221 Common - plasmid maintenance system antidote protein, XRE family Amet_0383 4 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 150390709 Common - 1,4-alpha-glucan branching enzyme Amet_2949 160 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 150392034 Nonpathogen - hypothetical protein Amet_4350 2 None None None 150389006 Nonpathogen - hypothetical protein Amet_1188 1 None None None 150392395 Common - methyl-accepting chemotaxis sensory transducer Amet_4717 137 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150388824 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Amet_0997 109 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 150389515 Common - DNA binding domain, excisionase family Amet_1729 23 None None None 150388046 Common - sugar transferase Amet_0201 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150388228 Nonpathogen - hypothetical protein Amet_0390 1 None None None 150388223 Nonpathogen - hypothetical protein Amet_0385 1 None None None 150392168 Common rpoB DNA-directed RNA polymerase subunit beta Amet_4486 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 150389650 Common - hypothetical protein Amet_1874 19 None None None 150390275 Common - Peptidase S55, sporulation stage IV, protein B Amet_2512 15 None None None 150389041 Common - acyl carrier protein Amet_1223 69 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150391918 Common - purine nucleoside phosphorylase Amet_4228 100 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 150388954 Common - binding-protein-dependent transport systems inner membrane component Amet_1133 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389470 Common - hypothetical protein Amet_1683 4 None None None 150390180 Common - uncharacterized phage protein Amet_2416 6 None None None 150388504 Common - D-proline reductase (dithiol) Amet_0669 2 None None None 150389477 Common - two component transcriptional regulator, winged helix family Amet_1691 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150388378 Common - Peptidoglycan-binding domain 1 protein Amet_0541 73 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 150389004 Common - SCP-like extracellular protein Amet_1186 59 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150392020 Common - amidohydrolase Amet_4336 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150390337 Nonpathogen - hypothetical protein Amet_2575 2 None None None 150390914 Common - polysaccharide biosynthesis protein Amet_3165 35 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150388700 Nonpathogen - hypothetical protein Amet_0865 1 None None None 150390402 Common - pseudouridine synthase Amet_2640 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150392473 Common - tRNA modification GTPase TrmE Amet_4797 225 COG0486 ThdF, Predicted GTPase General function prediction only 150392158 Common - Ribosomal protein L25/L23 Amet_4476 148 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 150390231 Common - beta-lactamase domain protein Amet_2467 163 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 150389760 Common - glycyl-radical enzyme activating protein family Amet_1987 61 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150387970 Common - hypothetical protein Amet_0119 38 None None None 150388823 Common - molybdenum cofactor synthesis domain Amet_0996 196 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 150391893 Common - integral membrane sensor signal transduction histidine kinase Amet_4203 139 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150389821 Common - hypothetical protein Amet_2050 6 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 150389965 Common - CRISPR-associated protein Cas2 Amet_2196 24 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150390811 Common - TPR repeat-containing protein Amet_3061 61 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150388425 Common - Monosaccharide-transporting ATPase Amet_0588 131 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 150390874 Common - DNA polymerase I Amet_3125 220 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 150388266 Nonpathogen - hypothetical protein Amet_0428 1 None None None 150391989 Common - 2-ketoisovalerate ferredoxin reductase Amet_4305 120 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150388189 Common - ATP synthase F0, B subunit Amet_0349 131 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 150389464 Common - 4-alpha-glucanotransferase Amet_1677 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 150390676 Common - NUDIX hydrolase Amet_2916 95 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150391199 Common - Na+/H+ antiporter NhaC Amet_3461 59 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 150388330 Nonpathogen - hypothetical protein Amet_0493 1 None None None 150388666 Common - 8-oxoguanine DNA glycosylase domain protein Amet_0831 25 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 150389356 Common - nucleoside recognition domain protein Amet_1562 22 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 150389902 Nonpathogen - hypothetical protein Amet_2133 3 None None None 150390263 Common - protein of unknown function DUF322 Amet_2500 35 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 150390589 Nonpathogen - hypothetical protein Amet_2829 1 None None None 150389558 Nonpathogen - hypothetical protein Amet_1776 1 None None None 150388678 Nonpathogen - hypothetical protein Amet_0843 1 None None None 150388155 Common - sodium:neurotransmitter symporter Amet_0315 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 150389080 Common - GntR domain protein Amet_1264 133 COG2186 FadR, Transcriptional regulators Transcription 150391277 Common - Nitric oxide reductase activation protein-like protein Amet_3541 15 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 150389891 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Amet_2122 90 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150390266 Common - exodeoxyribonuclease VII, large subunit Amet_2503 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 150388706 Common - spore germination protein Amet_0871 28 None None None 150391034 Common - binding-protein-dependent transport systems inner membrane component Amet_3293 199 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 150387905 Common - Radical SAM domain protein Amet_0052 177 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150389883 Common - Integrase, catalytic region Amet_2114 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388433 Nonpathogen - plasmid stabilization system Amet_0596 3 None None None 150388446 Common fliG flagellar motor switch protein G Amet_0609 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 150388707 Common - spore germination B3 GerAC family protein Amet_0872 15 None None None 150388209 Common - flagellar basal body rod protein Amet_0369 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 150390203 Nonpathogen - hypothetical protein Amet_2439 1 None None None 150390735 Common - branched chain amino acid transport system II carrier protein Amet_2976 40 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 150392123 Nonpathogen - hypothetical protein Amet_4441 1 None None None 150389726 Common - phage-associated protein, HI1409 family Amet_1953 17 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 150391205 Common - choline/carnitine/betaine transporter Amet_3467 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 150388760 Common - NLPA lipoprotein Amet_0930 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 150388696 Nonpathogen - hypothetical protein Amet_0861 1 None None None 150389427 Common pheT phenylalanyl-tRNA synthetase subunit beta Amet_1640 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 150391347 Common - cobalamin biosynthesis protein CobD Amet_3615 150 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 150389321 Common - two component transcriptional regulator, winged helix family Amet_1518 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150390102 Common - Holliday junction DNA helicase RuvA Amet_2338 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 150391146 Common - Triphosphoribosyl-dephospho-CoA synthase Amet_3408 50 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 150392262 Common - UbiD family decarboxylase Amet_4581 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 150389342 Nonpathogen - hypothetical protein Amet_1546 2 None None None 150392120 Common - protein of unknown function DUF610, YibQ Amet_4438 66 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 150391856 Nonpathogen - hypothetical protein Amet_4165 1 None None None 150389300 Common - NADPH-dependent FMN reductase Amet_1496 43 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150390100 Common - hypothetical protein Amet_2336 4 None None None 150391968 Common - hypothetical protein Amet_4281 3 None None None 150388998 Common - putative transcriptional regulator, Crp/Fnr family Amet_1180 180 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150391646 Nonpathogen - hypothetical protein Amet_3945 1 None None None 150391487 Common - L-fuculose phosphate aldolase Amet_3758 136 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 150390625 Common - multi-sensor signal transduction histidine kinase Amet_2865 224 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150391193 Common - 3-isopropylmalate dehydrogenase Amet_3455 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 150388568 Common - TPR repeat-containing protein Amet_0733 9 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150390393 Common - transcriptional regulator, RpiR family Amet_2631 103 COG1737 RpiR, Transcriptional regulators Transcription 150389990 Common - stage V sporulation protein AE Amet_2222 7 None None None 150390977 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Amet_3229 202 COG0281 SfcA, Malic enzyme Energy production and conversion 150391580 Common - Integrase, catalytic region Amet_3855 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389964 Common - CRISPR-associated protein Cas1 Amet_2195 91 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150390702 Common - membrane protein Amet_2942 7 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 150390011 Nonpathogen - hypothetical protein Amet_2243 1 None None None 150389320 Common - GCN5-related N-acetyltransferase Amet_1516 46 COG0456 RimI, Acetyltransferases General function prediction only 150389934 Common - proteinase inhibitor I4, serpin Amet_2165 29 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 150388101 Common - microcompartments protein Amet_0258 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150389688 Common - pyruvate phosphate dikinase, PEP/pyruvate-binding Amet_1914 152 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150391432 Common - GCN5-related N-acetyltransferase Amet_3702 49 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 150391457 Common - TRAP dicarboxylate transporter, DctM subunit Amet_3727 125 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150388875 Nonpathogen - hypothetical protein Amet_1050 1 None None None 150389095 Common - hypothetical protein Amet_1280 7 None None None 150388725 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_0893 5 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150392209 Common - putative TIM-barrel protein, nifR3 family Amet_4527 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 150391518 Common - transcriptional regulator, GntR family Amet_3789 128 COG1802 GntR, Transcriptional regulators Transcription 150390276 Common - response regulator receiver protein Amet_2513 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150389770 Common - hypothetical protein Amet_1997 16 None None None 150390769 Common - pyruvate phosphate dikinase Amet_3019 233 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150392431 Common - hypothetical protein Amet_4755 3 COG4863 COG4863, Uncharacterized protein conserved in bacteria Function unknown 150390356 Nonpathogen - hypothetical protein Amet_2594 1 None None None 150389130 Common - MazG nucleotide pyrophosphohydrolase Amet_1318 10 None None None 150390072 Common rpmA 50S ribosomal protein L27 Amet_2305 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 150390710 Common - GCN5-related N-acetyltransferase Amet_2950 13 COG0456 RimI, Acetyltransferases General function prediction only 150391427 Common - methionine sulfoxide reductase A Amet_3697 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150391874 Common anmK anhydro-N-acetylmuramic acid kinase Amet_4183 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 150391260 Common - nitrogen regulatory protein P-II Amet_3523 182 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150389074 Common - Phosphotransferase system, phosphocarrier protein HPr Amet_1258 150 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 150392424 Common - hypothetical protein Amet_4748 4 None None None 150388868 Common - Abortive infection protein Amet_1042 39 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 150388896 Common - 3-dehydroquinate dehydratase Amet_1074 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 150389169 Common - Hemerythrin HHE cation binding domain protein Amet_1359 23 COG3945 COG3945, Uncharacterized conserved protein Function unknown 150391697 Common - Resolvase, N-terminal domain Amet_4005 83 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150391616 Nonpathogen - hypothetical protein Amet_3910 1 None None None 150390963 Common - transcriptional regulator, LysR family Amet_3215 192 COG0583 LysR, Transcriptional regulator Transcription 150388962 Common - DNA topoisomerase, type IA, central domain protein Amet_1141 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150390908 Common - ABC transporter related Amet_3159 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150389801 Common - glycine cleavage system H protein Amet_2029 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 150391350 Common - transport system permease protein Amet_3618 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150388667 Common - protein of unknown function DUF554 Amet_0832 48 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 150390322 Common - phage-like element pbsx protein XkdS Amet_2560 3 None None None 150389537 Common - hypothetical protein Amet_1754 11 COG1103 COG1103, Archaea-specific pyridoxal phosphate-dependent enzymes General function prediction only 150389121 Nonpathogen - hypothetical protein Amet_1306 1 None None None 150392316 Common - hypothetical protein Amet_4635 16 COG2308 COG2308, Uncharacterized conserved protein Function unknown 150392345 Common - protein of unknown function DUF1063 Amet_4665 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 150388843 Common - nucleoside recognition domain protein Amet_1016 23 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 150390340 Nonpathogen - hypothetical protein Amet_2578 2 None None None 150392107 Common - lipoyl synthase Amet_4425 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 150390731 Nonpathogen - hypothetical protein Amet_2971 2 None None None 150391948 Common - channel protein, hemolysin III family Amet_4260 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 150388203 Common - acriflavin resistance protein Amet_0363 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150391545 Common - transposase IS200-family protein Amet_3817 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388106 Common - ethanolamine utilization protein EutJ family protein Amet_0263 24 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 150388441 Common - uracil-xanthine permease Amet_0604 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150391934 Common - 3-oxoacid CoA-transferase, B subunit Amet_4246 108 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 150391065 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_3327 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150391421 Common - putative metal dependent phosphohydrolase Amet_3691 10 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150388131 Common - integral membrane sensor signal transduction histidine kinase Amet_0289 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391887 Common - transcriptional regulator, TrmB Amet_4197 160 COG3933 COG3933, Transcriptional antiterminator Transcription 150389139 Common - phosphonate ABC transporter, inner membrane subunit Amet_1327 92 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 150391528 Common - putative solute-binding component of ABC transporter Amet_3799 91 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 150389017 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Amet_1199 112 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150390864 Common - glycerophosphoryl diester phosphodiesterase Amet_3115 163 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 150391074 Common - ABC transporter related Amet_3336 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150392185 Common - glutamyl-tRNA synthetase Amet_4503 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150390948 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Amet_3200 205 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150389633 Nonpathogen - hypothetical protein Amet_1854 1 None None None 150389673 Common - ATPase associated with various cellular activities, AAA_5 Amet_1899 15 COG0714 COG0714, MoxR-like ATPases General function prediction only 150388350 Common - spore germination protein Amet_0513 15 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 150389181 Common - hypothetical protein Amet_1371 4 None None None 150389256 Common - UspA domain protein Amet_1447 132 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 150389199 Nonpathogen - hypothetical protein Amet_1389 1 None None None 150387875 Common - protein of unknown function UPF0182 Amet_0022 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 150390615 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Amet_2855 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 150390560 Common - DivIVA family protein Amet_2800 48 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 150388921 Common - integral membrane sensor signal transduction histidine kinase Amet_1100 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150391045 Nonpathogen - hypothetical protein Amet_3306 1 None None None 150391495 Common - sigma54 specific transcriptional regulator, Fis family Amet_3766 178 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150388056 Common - hypothetical protein Amet_0211 16 None None None 150388419 Common - methyl-accepting chemotaxis sensory transducer Amet_0582 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150389082 Common - Uncharacterized protein UPF0065 Amet_1266 68 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 150390540 Common - Protein phosphatase 2C-like protein Amet_2780 137 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 150389059 Common - extracellular solute-binding protein, family 3 Amet_1242 178 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150389193 Common - polysaccharide biosynthesis protein Amet_1383 56 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 150390047 Common - electron transport complex, RnfABCDGE type, C subunit Amet_2280 75 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150392419 Common - binding-protein-dependent transport systems inner membrane component Amet_4743 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150390229 Common - sugar fermentation stimulation protein Amet_2465 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 150390095 Common - alpha/beta hydrolase fold Amet_2331 156 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150390526 Common - Sporulation integral membrane protein YlbJ Amet_2765 27 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 150391407 Common - metallophosphoesterase Amet_3677 15 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 150389617 Common - regulatory protein, ArsR Amet_1837 90 COG0640 ArsR, Predicted transcriptional regulators Transcription 150390502 Common - GTP-binding protein, HSR1-related Amet_2741 117 COG1161 COG1161, Predicted GTPases General function prediction only 150391079 Nonpathogen - hypothetical protein Amet_3341 1 None None None 150388739 Common - thioesterase family protein Amet_0908 38 COG5496 COG5496, Predicted thioesterase General function prediction only 150388113 Common - putative transcriptional regulator, TetR family Amet_0270 13 COG1309 AcrR, Transcriptional regulator Transcription 150388572 Nonpathogen - hypothetical protein Amet_0737 2 None None None 150388805 Common - hypothetical protein Amet_0978 8 None None None 150389675 Common - transcriptional regulator, XRE family Amet_1901 15 COG1396 HipB, Predicted transcriptional regulators Transcription 150390441 Common - glycosyl transferase, family 2 Amet_2679 75 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150388281 Common - Electron transfer flavoprotein, alpha subunit-like protein Amet_0443 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150392219 Nonpathogen - sodium pump decarboxylase, gamma subunit Amet_4537 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 150389044 Common - cyanophycinase Amet_1226 32 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 150388960 Common - heavy metal translocating P-type ATPase Amet_1139 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150387979 Common - heavy metal translocating P-type ATPase Amet_0130 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150392412 Common - transcriptional repressor, CopY family Amet_4736 10 COG3682 COG3682, Predicted transcriptional regulator Transcription 150387898 Common - Heavy metal transport/detoxification protein Amet_0045 84 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150391659 Common - protein kinase Amet_3962 64 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 150390383 Common - Cellulase Amet_2621 88 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 150388438 Common - Radical SAM domain protein Amet_0601 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150388290 Common - heat shock protein DnaJ domain protein Amet_0452 152 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150392326 Common - peptidase M28 Amet_4645 20 COG2234 Iap, Predicted aminopeptidases General function prediction only 150388128 Common - Tetratricopeptide TPR_2 repeat protein Amet_0286 4 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150388401 Common - hypothetical protein Amet_0564 27 COG3875 COG3875, Uncharacterized conserved protein Function unknown 150390771 Common - CBS domain containing protein Amet_3021 26 COG0517 COG0517, FOG: CBS domain General function prediction only 150390754 Common - Succinate dehydrogenase Amet_3000 90 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150392068 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Amet_4384 122 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150391906 Common - DNA-directed DNA polymerase Amet_4216 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 150389716 Common - 3D domain protein Amet_1943 14 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150390224 Common - hypothetical protein Amet_2460 11 None None None 150389957 Common - transposase Amet_2188 6 None None None 150388191 Common - ATP synthase F1, alpha subunit Amet_0351 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 150389761 Nonpathogen - membrane protein Amet_1988 5 None None None 150389610 Common - arsenite-activated ATPase ArsA Amet_1830 94 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 150392385 Nonpathogen - hypothetical protein Amet_4707 1 None None None 150391560 Common - hypothetical protein Amet_3833 18 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 150391766 Common - urocanate hydratase Amet_4074 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 150389861 Nonpathogen - hypothetical protein Amet_2091 1 None None None 150389850 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Amet_2080 206 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150391662 Nonpathogen - hypothetical protein Amet_3965 2 None None None 150390778 Common - hypothetical protein Amet_3028 14 None None None 150388819 Common - cytoplasmic chaperone TorD family protein Amet_0992 24 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 150388162 Common glpX fructose 1,6-bisphosphatase II Amet_0322 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 150388397 Common - TRAP dicarboxylate transporter, DctM subunit Amet_0560 125 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150389285 Common - transcriptional regulator, TrmB Amet_1479 42 COG1846 MarR, Transcriptional regulators Transcription 150389727 Common - phage putative head morphogenesis protein, SPP1 gp7 family Amet_1954 17 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 150391254 Common - nitrogenase cofactor biosynthesis protein NifB Amet_3517 114 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150390618 Common - response regulator receiver protein Amet_2858 31 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 150392360 Nonpathogen - hypothetical protein Amet_4682 1 None None None 150388833 Common - polynucleotide phosphorylase/polyadenylase Amet_1006 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 150391053 Nonpathogen - hypothetical protein Amet_3315 1 None None None 150391399 Common - protein of unknown function DUF187 Amet_3669 49 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 150391185 Nonpathogen - hypothetical protein Amet_3447 1 None None None 150390305 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Amet_2542 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 150388313 Common - peptidase U61, LD-carboxypeptidase A Amet_0476 88 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 150388607 Common - hypothetical protein Amet_0772 6 None None None 150391022 Common - 40-residue YVTN family beta-propeller repeat protein Amet_3275 96 COG3391 COG3391, Uncharacterized conserved protein Function unknown 150389373 Common - two component transcriptional regulator, LuxR family Amet_1584 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150387980 Common uvsE putative UV damage endonuclease Amet_0131 30 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 150390838 Nonpathogen - hypothetical protein Amet_3088 1 None None None 150391243 Common - hypothetical protein Amet_3506 8 None None None 150392301 Common - phosphate uptake regulator, PhoU Amet_4620 199 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 150389720 Nonpathogen - hypothetical protein Amet_1947 1 None None None 150388410 Common - histidinol-phosphate aminotransferase Amet_0573 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150390215 Common - dTDP-4-dehydrorhamnose reductase Amet_2451 170 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 150388861 Nonpathogen - hypothetical protein Amet_1034 1 None None None 150390883 Nonpathogen - hypothetical protein Amet_3134 2 None None None 150390944 Common - Dihydrodipicolinate reductase Amet_3196 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 150390728 Common - peptidase C26 Amet_2968 135 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 150392256 Common - Ethanolamine utilization protein EutN/carboxysome structural protein Ccml Amet_4575 39 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150388096 Common - signal transduction histidine kinase Amet_0253 123 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 150392003 Nonpathogen - hypothetical protein Amet_4319 2 None None None 150387964 Nonpathogen - hypothetical protein Amet_0113 1 None None None 150391686 Common - Cobyrinic acid a,c-diamide synthase Amet_3994 235 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150389738 Nonpathogen - hypothetical protein Amet_1965 1 None None None 150391224 Common - Methyltransferase type 12 Amet_3486 49 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150388813 Common - arsenite-activated ATPase ArsA Amet_0986 94 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 150391250 Common - Uncharacterized protein UPF0065 Amet_3513 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 150390901 Common - peptidase M23B Amet_3152 183 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150391010 Common - NLP/P60 protein Amet_3262 150 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150391085 Nonpathogen - hypothetical protein Amet_3347 1 None None None 150388210 Common - protein of unknown function DUF1078 domain protein Amet_0370 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 150390712 Common - DEAD/DEAH box helicase domain protein Amet_2952 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150389129 Common - integral membrane protein MviN Amet_1317 196 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 150389920 Nonpathogen - hypothetical protein Amet_2151 8 None None None 150390314 Common - hypothetical protein Amet_2552 10 None None None 150389317 Common - binding-protein-dependent transport systems inner membrane component Amet_1513 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150387881 Common - hypothetical protein Amet_0028 7 None None None 150388630 Common - flagellin domain protein Amet_0795 120 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 150392371 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_4693 157 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150392449 Common - hypothetical protein Amet_4773 42 COG4129 COG4129, Predicted membrane protein Function unknown 150391567 Common - membrane spanning protein Amet_3840 12 None None None 150391770 Nonpathogen - hypothetical protein Amet_4078 1 None None None 150388991 Common - ABC transporter related Amet_1173 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 150389792 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Amet_2020 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 150389841 Common - transcriptional regulator, TetR family Amet_2070 58 COG1309 AcrR, Transcriptional regulator Transcription 150391335 Common - uncharacterised conserved protein UCP033563 Amet_3603 49 COG4198 COG4198, Uncharacterized conserved protein Function unknown 150390930 Common - sodium:dicarboxylate symporter Amet_3182 156 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 150392251 Common - (2Fe-2S)-binding domain protein Amet_4570 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 150389478 Common - integral membrane sensor signal transduction histidine kinase Amet_1692 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150392319 Common - methyl-accepting chemotaxis sensory transducer Amet_4638 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150389739 Nonpathogen - hypothetical protein Amet_1966 1 None None None 150390147 Common - hypothetical protein Amet_2383 32 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150389318 Common - binding-protein-dependent transport systems inner membrane component Amet_1514 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390417 Common - PHP C-terminal domain protein Amet_2655 135 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 150388876 Nonpathogen - hypothetical protein Amet_1053 1 None None None 150391757 Common - hypothetical protein Amet_4065 8 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150390593 Nonpathogen - hypothetical protein Amet_2833 1 None None None 150392186 Common - protein of unknown function DUF1002 Amet_4504 12 COG4086 COG4086, Predicted secreted protein Function unknown 150387857 Common - DNA replication and repair protein RecF Amet_0004 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 150390606 Common - Integrase, catalytic region Amet_2846 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388323 Common - hypothetical protein Amet_0486 3 None None None 150390807 Common - DNA polymerase III, delta subunit Amet_3057 51 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 150390479 Common - flagellar operon protein Amet_2717 16 None None None 150390119 Common - beta-lactamase domain protein Amet_2355 224 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150389475 Common - protein of unknown function DUF214 Amet_1689 17 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 150390427 Common - peptidase M16 domain protein Amet_2665 203 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150392143 Common - ribosomal protein S5 Amet_4461 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 150392351 Common - transcriptional regulator, TetR family Amet_4671 77 COG1309 AcrR, Transcriptional regulator Transcription 150388342 Common - 2-dehydro-3-deoxyglucarate aldolase Amet_0505 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 150390456 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG Amet_2694 213 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150390645 Common - Peptidoglycan glycosyltransferase Amet_2885 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150390678 Common - cytochrome c assembly protein Amet_2918 185 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 150391711 Common - hypothetical protein Amet_4019 36 COG5412 COG5412, Phage-related protein Function unknown 150390448 Common - ribosome recycling factor Amet_2686 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 150390987 Nonpathogen - hypothetical protein Amet_3239 1 None None None 150388365 Nonpathogen - protein of unknown function DUF34 Amet_0528 5 COG0327 COG0327, Uncharacterized conserved protein Function unknown 150391060 Common - histidine kinase internal region Amet_3322 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150388147 Common - glycosyl transferase, family 2 Amet_0306 187 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150390995 Common - Tn554-related, transposase A Amet_3247 9 None None None 150391639 Common - hypothetical protein Amet_3938 7 None None None 150389901 Common - transposase IS116/IS110/IS902 family protein Amet_2132 77 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150387908 Common - SirA family protein Amet_0055 22 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 150391280 Nonpathogen - hypothetical protein Amet_3544 1 None None None 150391693 Nonpathogen - hypothetical protein Amet_4001 1 None None None 150390055 Common - maf protein Amet_2288 195 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 150390376 Nonpathogen - hypothetical protein Amet_2614 2 None None None 150387989 Common - sodium/calcium exchanger membrane region Amet_0140 113 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 150392072 Nonpathogen - hypothetical protein Amet_4388 1 None None None 150390957 Common - two component transcriptional regulator, winged helix family Amet_3209 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391357 Common - hypothetical protein Amet_3625 16 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 150390334 Common - hypothetical protein Amet_2572 2 None None None 150387969 Common - transposase, IS4 family protein Amet_0118 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150388545 Common - spore germination protein-like protein Amet_0710 6 COG5401 COG5401, Spore germination protein General function prediction only 150392454 Common - hypothetical protein Amet_4778 4 None None None 150388095 Common - response regulator receiver and ANTAR domain protein Amet_0252 222 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 150391647 Common - hypothetical protein Amet_3946 4 None None None 150392045 Common - hypothetical protein Amet_4361 11 COG4834 COG4834, Uncharacterized protein conserved in bacteria Function unknown 150392174 Common - preprotein translocase, SecE subunit Amet_4492 26 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 150392349 Common - hypothetical protein Amet_4669 7 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 150390574 Common - Monosaccharide-transporting ATPase Amet_2814 106 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 150388406 Common - Phosphotransferase system, phosphocarrier protein HPr Amet_0569 145 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 150389038 Common - RNA binding S1 domain protein Amet_1220 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 150392442 Common - conserved hypothetical protein, CF-27 family Amet_4766 10 None None None 150388554 Nonpathogen - hypothetical protein Amet_0719 1 None None None 150388681 Common - hypothetical protein Amet_0846 39 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150392177 Common - RNA polymerase factor sigma-70 Amet_4495 82 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150388434 Common - transcriptional regulator, TetR family Amet_0597 101 COG1309 AcrR, Transcriptional regulator Transcription 150390110 Common - Radical SAM domain protein Amet_2346 108 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 150388586 Nonpathogen - hypothetical protein Amet_0751 1 None None None 150391632 Nonpathogen - hypothetical protein Amet_3929 1 None None None 150388713 Nonpathogen - hypothetical protein Amet_0881 1 None None None 150390141 Common - Resolvase, N-terminal domain Amet_2377 133 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150392443 Common - GCN5-related N-acetyltransferase Amet_4767 31 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150389021 Nonpathogen - hypothetical protein Amet_1203 1 None None None 150392466 Common - phenazine biosynthesis protein PhzF family Amet_4790 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 150388655 Common - Electron transfer flavoprotein, alpha subunit-like protein Amet_0820 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150389407 Common - putative GAF sensor protein Amet_1620 85 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 150391671 Nonpathogen - hypothetical protein Amet_3976 1 None None None 150392472 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Amet_4796 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 150389652 Common - binding-protein-dependent transport systems inner membrane component Amet_1877 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389068 Common - Transketolase, central region Amet_1252 206 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 150391276 Nonpathogen - hypothetical protein Amet_3540 1 None None None 150388045 Common - hypothetical protein Amet_0200 25 None None None 150390269 Common - acid phosphatase/vanadium-dependent haloperoxidase related Amet_2506 28 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 150389736 Common - hypothetical protein Amet_1963 10 None None None 150390022 Nonpathogen - hypothetical protein Amet_2254 1 None None None 150390646 Nonpathogen - hypothetical protein Amet_2886 1 None None None 150390264 Common - NusB antitermination factor Amet_2501 156 COG0781 NusB, Transcription termination factor Transcription 150388449 Common - flagellar motor switch protein FliN Amet_0613 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 150390232 Common - hypothetical protein Amet_2468 3 None None None 150389586 Nonpathogen - hypothetical protein Amet_1806 1 None None None 150388026 Nonpathogen - hypothetical protein Amet_0179 1 None None None 150389882 Common - IstB domain protein ATP-binding protein Amet_2113 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150388229 Nonpathogen - hypothetical protein Amet_0391 1 None None None 150389127 Nonpathogen - hypothetical protein Amet_1313 1 None None None 150391640 Common - hypothetical protein Amet_3939 15 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 150388358 Common - heat shock protein 90 Amet_0521 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 150391902 Common - orotidine 5'-phosphate decarboxylase Amet_4212 68 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 150389657 Common - peptidase M19, renal dipeptidase Amet_1882 103 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 150389442 Common - hypothetical protein Amet_1655 2 None None None 150389345 Common - flavocytochrome c Amet_1551 207 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150391959 Common - PTS system, mannitol-specific IIC subunit Amet_4271 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 150388822 Common - molybdopterin binding domain Amet_0995 82 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 150388422 Common - exodeoxyribonuclease III Xth Amet_0585 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 150391273 Common - glycosyltransferase 36 Amet_3537 48 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 150391846 Common - hypothetical protein Amet_4155 23 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 150390628 Common - ATP-cone domain protein Amet_2868 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 150391003 Common - two component, sigma54 specific, transcriptional regulator, Fis family Amet_3255 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150391476 Common - FAD linked oxidase domain protein Amet_3747 203 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150389979 Common - formate acetyltransferase Amet_2211 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150388445 Common - flagellar M-ring protein FliF Amet_0608 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 150388052 Common - UDP-N-acetylglucosamine 2-epimerase Amet_0207 156 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 150391683 Common - hypothetical protein Amet_3991 4 None None None 150388818 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_0991 166 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 150388865 Common - Radical SAM domain protein Amet_1039 154 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150391712 Common - hypothetical protein Amet_4020 4 None None None 150391967 Common - Abortive infection protein Amet_4279 19 None None None 150390782 Common - metal dependent phosphohydrolase Amet_3032 60 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 150388135 Common - S-layer domain protein Amet_0293 24 None None None 150389359 Nonpathogen - hypothetical protein Amet_1569 1 None None None 150388175 Common - Peptidoglycan glycosyltransferase Amet_0335 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150389142 Common - molybdopterin oxidoreductase Amet_1330 172 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 150392150 Common - ribosomal protein L14 Amet_4468 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 150387971 Nonpathogen - hypothetical protein Amet_0121 1 None None None 150388699 Common - transcriptional repressor, LexA family Amet_0864 22 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150389555 Common - cell wall/surface repeat protein Amet_1773 33 None None None 150391605 Common - hypothetical protein Amet_3897 41 None None None 150392122 Common - N-acetylmuramoyl-L-alanine amidase CwlD Amet_4440 181 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150391021 Common - integral membrane protein TIGR01906 Amet_3274 10 COG4478 COG4478, Predicted membrane protein Function unknown 150391630 Nonpathogen - hypothetical protein Amet_3927 1 None None None 150389685 Common - helix-turn-helix- domain containing protein, AraC type Amet_1911 139 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150389557 Common - protein of unknown function DUF6, transmembrane Amet_1775 82 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150389946 Nonpathogen - hypothetical protein Amet_2177 1 None None None 150388513 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Amet_0678 231 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 150391106 Nonpathogen - hypothetical protein Amet_3368 1 None None None 150391521 Nonpathogen - hypothetical protein Amet_3792 2 None None None 150388721 Common - protein of unknown function DUF6, transmembrane Amet_0889 83 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150391158 Common - Domain of unknown function DUF1846 Amet_3420 7 COG4868 COG4868, Uncharacterized protein conserved in bacteria Function unknown 150389053 Common - ErfK/YbiS/YcfS/YnhG family protein Amet_1236 106 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150392027 Common - hypothetical protein Amet_4343 3 None None None 150390664 Common - ATP--cobalamin adenosyltransferase Amet_2904 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 150390968 Common - oxaloacetate decarboxylase Amet_3220 175 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 150389905 Common - hypothetical protein Amet_2136 8 None None None 150390422 Common - MiaB-like tRNA modifying enzyme YliG Amet_2660 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150389001 Nonpathogen - hypothetical protein Amet_1183 1 None None None 150389227 Nonpathogen - hypothetical protein Amet_1417 1 None None None 150388844 Common - nucleoside recognition domain protein Amet_1017 18 None None None 150392367 Nonpathogen - hypothetical protein Amet_4689 1 None None None 150389644 Nonpathogen - hypothetical protein Amet_1868 1 None None None 150390797 Common - chaperone protein DnaJ Amet_3047 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150389335 Nonpathogen - hypothetical protein Amet_1535 4 None None None 150391062 Common - transcriptional regulator, CdaR Amet_3324 33 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 150392322 Nonpathogen - metallophosphoesterase, calcineurin superfamily Amet_4641 4 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150390398 Common - stationary-phase survival protein SurE Amet_2636 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 150391576 Common - transcriptional regulator, TetR family Amet_3851 6 COG1309 AcrR, Transcriptional regulator Transcription 150392070 Nonpathogen - hypothetical protein Amet_4386 1 None None None 150389452 Common - CRISPR-associated protein, Csd2 family Amet_1665 55 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150387935 Common - dTMP kinase Amet_0082 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 150391398 Nonpathogen - hypothetical protein Amet_3668 2 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 150391419 Common - hypothetical protein Amet_3689 2 None None None 150390591 Nonpathogen - hypothetical protein Amet_2831 3 None None None 150390326 Common - phage tail tape measure protein, TP901 family Amet_2564 62 COG5283 COG5283, Phage-related tail protein Function unknown 150390553 Common - Diaminopimelate epimerase Amet_2793 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 150390824 Common - spore germination B3 GerAC family protein Amet_3074 7 None None None 150390467 Common fliR flagellar biosynthesis protein FliR Amet_2705 129 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 150392182 Common - ribonuclease III Amet_4500 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 150389369 Common - hypothetical protein Amet_1580 80 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150388750 Common - phosphoribosylformylglycinamidine synthase I Amet_0920 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 150388791 Common - S-layer domain protein Amet_0963 37 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150388777 Common - small GTP-binding protein Amet_0947 167 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 150391293 Common - Integrase, catalytic region Amet_3561 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150387938 Common - PSP1 domain protein Amet_0085 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 150392088 Common - asparagine synthase (glutamine-hydrolyzing) Amet_4405 165 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 150388653 Common - GntR domain protein Amet_0818 153 COG2186 FadR, Transcriptional regulators Transcription 150388348 Common - Catalase Amet_0511 129 COG0753 KatE, Catalase Inorganic ion transport and metabolism 150388264 Common - hypothetical protein Amet_0426 10 None None None 150392036 Nonpathogen - hypothetical protein Amet_4352 1 None None None 150389669 Common - hypothetical protein Amet_1894 15 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 150388267 Nonpathogen - hypothetical protein Amet_0429 1 None None None 150389662 Common - peptidase S41 Amet_1887 4 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150389548 Common - IstB domain protein ATP-binding protein Amet_1766 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150392217 Common - sodium ion-translocating decarboxylase, beta subunit Amet_4535 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 150389858 Nonpathogen - hypothetical protein Amet_2088 1 None None None 150391305 Nonpathogen - protein of unknown function DUF1294 Amet_3573 1 COG3326 COG3326, Predicted membrane protein Function unknown 150389971 Common - Asparaginase/glutaminase Amet_2203 139 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 150392234 Common - lysine 2,3-aminomutase YodO family protein Amet_4552 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 150388809 Nonpathogen - hypothetical protein Amet_0982 1 None None None 150392257 Nonpathogen - hypothetical protein Amet_4576 3 None None None 150390445 Common - phosphatidate cytidylyltransferase Amet_2683 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 150391334 Common - oxidoreductase domain protein Amet_3602 188 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150390510 Common - signal recognition particle-docking protein FtsY Amet_2749 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 150389010 Common - amidohydrolase Amet_1192 174 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150389247 Nonpathogen - hypothetical protein Amet_1438 1 None None None 150389292 Common - cell wall hydrolase/autolysin Amet_1486 93 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150392017 Common - hypothetical protein Amet_4333 7 None None None 150391781 Common - NUDIX hydrolase Amet_4090 42 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150389805 Common - hypothetical protein Amet_2033 11 None None None 150390608 Nonpathogen - hypothetical protein Amet_2848 1 None None None 150391928 Nonpathogen - hypothetical protein Amet_4238 1 None None None 150389421 Common - ribosomal protein L35 Amet_1634 139 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 150392159 Common - ribosomal protein L4/L1e Amet_4477 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 150388955 Common - ABC transporter related Amet_1134 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389026 Nonpathogen - hypothetical protein Amet_1208 1 None None None 150389386 Common - helix-turn-helix domain protein Amet_1597 6 None None None 150391704 Common - hypothetical protein Amet_4012 15 None None None 150391114 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Amet_3376 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150388351 Common - GerA spore germination protein Amet_0514 15 None None None 150389541 Nonpathogen - hypothetical protein Amet_1759 1 None None None 150390344 Common - DNA methylase N-4/N-6 domain protein Amet_2582 75 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 150391161 Common - hypothetical protein Amet_3423 5 None None None 150390185 Common - phage-like element pbsx protein XkdM Amet_2421 4 None None None 150388582 Common - addiction module toxin, RelE/StbE family Amet_0747 9 COG3668 ParE, Plasmid stabilization system protein General function prediction only 150388548 Common - protein of unknown function DUF1256 Amet_0713 14 None None None 150392381 Common - TRAP transporter solute receptor, TAXI family Amet_4703 91 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 150389188 Common - two component transcriptional regulator, LytTR family Amet_1378 212 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150390736 Common - hypothetical protein Amet_2977 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 150391503 Common - periplasmic binding protein Amet_3774 74 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150392141 Common - ribosomal protein L15 Amet_4459 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 150389447 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Amet_1660 92 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 150389218 Common - hypothetical protein Amet_1408 14 None None None 150390330 Common - hypothetical protein Amet_2568 6 None None None 150389299 Nonpathogen - hypothetical protein Amet_1495 1 None None None 150388783 Common - N-acetylmuramoyl-L-alanine amidase Amet_0953 182 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150389289 Common - hypothetical protein Amet_1483 10 None None None 150390478 Common - protein of unknown function DUF1078 domain protein Amet_2716 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 150388919 Common - hypothetical protein Amet_1097 3 None None None 150392006 Common - hypothetical protein Amet_4322 14 COG4828 COG4828, Predicted membrane protein Function unknown 150390088 Common - selenide, water dikinase Amet_2321 136 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 150391191 Nonpathogen - hypothetical protein Amet_3453 2 None None None 150391869 Nonpathogen - hypothetical protein Amet_4178 2 None None None 150389600 Nonpathogen - hypothetical protein Amet_1820 1 None None None 150389931 Common - dihydroneopterin aldolase Amet_2162 128 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 150388501 Common - hypothetical protein Amet_0666 2 None None None 150388475 Common - NADH dehydrogenase (quinone) Amet_0640 179 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150389502 Common - hypothetical protein Amet_1716 2 None None None 150390403 Common - glucose-inhibited division protein A Amet_2641 6 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 150392022 Common - succinic semialdehyde dehydrogenase Amet_4338 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150388677 Common - phage protein Amet_0842 10 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150389533 Nonpathogen - hypothetical protein Amet_1750 1 None None None 150389693 Common - ABC transporter related Amet_1919 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150392199 Common - superoxide dismutase, copper/zinc binding Amet_4517 85 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 150389124 Nonpathogen - hypothetical protein Amet_1310 1 None None None 150390758 Common - hypothetical protein Amet_3004 6 None None None 150389953 Common - Resolvase, N-terminal domain Amet_2184 14 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150388188 Nonpathogen - ATP synthase F0, C subunit Amet_0348 1 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 150389282 Common - ThiJ/PfpI domain protein Amet_1474 118 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150391011 Nonpathogen - hypothetical protein Amet_3263 1 None None None 150389155 Common - Cysteine desulfurase Amet_1345 236 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150391228 Common - aminotransferase, class I and II Amet_3490 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150389715 Nonpathogen - hypothetical protein Amet_1942 1 None None None 150391449 Common - ABC transporter related Amet_3719 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150390889 Common - putative aminopeptidase 1 Amet_3140 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 150388252 Common - NusG antitermination factor Amet_0414 188 COG0250 NusG, Transcription antiterminator Transcription 150389395 Common - restriction modification system DNA specificity domain Amet_1608 57 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 150391206 Common - glucose-6-phosphate 1-dehydrogenase Amet_3468 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 150390029 Common - GCN5-related N-acetyltransferase Amet_2261 24 COG0456 RimI, Acetyltransferases General function prediction only 150390506 Common - RNA-binding protein (KH domain) Amet_2745 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 150389983 Nonpathogen - hypothetical protein Amet_2215 1 None None None 150390898 Common - histidine ammonia-lyase Amet_3149 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 150392220 Common - carboxyl transferase Amet_4538 211 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 150388399 Common - glycerol-3-phosphate responsive antiterminator Amet_0562 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 150388316 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Amet_0479 52 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150392295 Nonpathogen - hypothetical protein Amet_4614 1 None None None 150391168 Common - SCP-like extracellular protein Amet_3430 53 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150390433 Common - phosphoesterase, RecJ domain protein Amet_2671 86 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 150391210 Common - hypothetical protein Amet_3472 7 None None None 150392263 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Amet_4582 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 150389329 Nonpathogen - hypothetical protein Amet_1527 2 None None None 150389428 Common - protein of unknown function DUF710 Amet_1641 19 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 150389487 Common - Peptidase M16C associated domain protein Amet_1701 63 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 150389915 Common - helicase domain protein Amet_2146 31 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150391446 Common - integral membrane sensor signal transduction histidine kinase Amet_3716 126 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150389723 Common - hypothetical protein Amet_1950 10 None None None 150390060 Common - penicillin-binding protein, transpeptidase Amet_2293 194 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150391999 Nonpathogen - hypothetical protein Amet_4315 1 None None None 150390274 Common - DNA repair protein RecN Amet_2511 210 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 150392341 Common - hemerythrin-like metal-binding protein Amet_4661 50 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150387914 Common - uroporphyrin-III C-methyltransferase Amet_0061 209 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 150387996 Common - AbgT putative transporter Amet_0147 44 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 150391820 Common - peptidase M23B Amet_4129 201 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150391981 Common - Methyltransferase type 12 Amet_4295 41 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150388496 Common - C4-dicarboxylate anaerobic carrier Amet_0661 61 COG1288 COG1288, Predicted membrane protein Function unknown 150388634 Common - RNA binding S1 domain protein Amet_0799 221 COG2183 Tex, Transcriptional accessory protein Transcription 150388800 Common - FAD dependent oxidoreductase Amet_0973 139 COG0579 COG0579, Predicted dehydrogenase General function prediction only 150390019 Nonpathogen - hypothetical protein Amet_2251 1 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 150390452 Nonpathogen - hypothetical protein Amet_2690 1 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 150392434 Common - two component transcriptional regulator, winged helix family Amet_4758 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150388080 Common - abortive infection protein, putative Amet_0237 24 COG1106 COG1106, Predicted ATPases General function prediction only 150390258 Common - Sporulation stage III, protein AD Amet_2495 15 None None None 150391834 Common - transcriptional modulator of MazE/toxin, MazF Amet_4143 59 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 150388642 Nonpathogen - hypothetical protein Amet_0807 1 None None None 150390535 Common - transposase, IS4 family protein Amet_2775 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150388546 Common - Auxin Efflux Carrier Amet_0711 134 COG0679 COG0679, Predicted permeases General function prediction only 150390804 Common - Stage II sporulation P family protein Amet_3054 15 None None None 150390925 Common - response regulator receiver protein Amet_3176 148 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150391824 Common - peptidase S16, lon domain protein Amet_4133 139 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 150392223 Common - cobalamin B12-binding domain protein Amet_4541 110 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 150389740 Common - phage tail tape measure protein, TP901 family Amet_1967 19 COG5280 COG5280, Phage-related minor tail protein Function unknown 150391344 Common - Cof-like hydrolase Amet_3612 134 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150392146 Common - ribosomal protein S8 Amet_4464 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 150390158 Nonpathogen - hypothetical protein Amet_2394 1 None None None 150390750 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Amet_2996 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 150388834 Common - NUDIX hydrolase Amet_1007 18 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150392113 Common - butyrate kinase Amet_4431 133 COG3426 COG3426, Butyrate kinase Energy production and conversion 150391666 Common - Integrase, catalytic region Amet_3970 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388524 Common - protein of unknown function DUF1116 Amet_0689 17 None None None 150390392 Common - Phosphoglycerate mutase Amet_2630 198 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150388717 Nonpathogen - hypothetical protein Amet_0885 1 None None None 150388884 Nonpathogen - hypothetical protein Amet_1062 1 None None None 150389222 Nonpathogen - hypothetical protein Amet_1412 1 None None None 150390121 Common - coproporphyrinogen III oxidase Amet_2357 215 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150389360 Common - catalase/peroxidase HPI Amet_1570 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 150388612 Common - RNA-metabolising metallo-beta-lactamase Amet_0777 129 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 150391585 Common - transcriptional regulator, TetR family Amet_3862 33 COG1309 AcrR, Transcriptional regulator Transcription 150390457 Common - CheD Amet_2695 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 150392298 Common - Na+/H+ antiporter NhaC Amet_4617 66 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 150389030 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Amet_1212 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150392054 Nonpathogen - hypothetical protein Amet_4370 1 None None None 150389526 Nonpathogen - hypothetical protein Amet_1741 1 None None None 150390524 Common - acetate kinase Amet_2763 162 COG0282 ackA, Acetate kinase Energy production and conversion 150391440 Common - D-alanine--D-alanine ligase Amet_3710 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150391816 Nonpathogen - hypothetical protein Amet_4125 3 None None None 150388261 Common - hypothetical protein Amet_0423 5 None None None 150389777 Common - hypothetical protein Amet_2004 4 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 150391676 Nonpathogen - hypothetical protein Amet_3981 1 None None None 150390616 Common - protein of unknown function DUF205 Amet_2856 170 COG0344 COG0344, Predicted membrane protein Function unknown 150390983 Common - Rhodanese domain protein Amet_3235 166 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150391077 Common - cytochrome P450 family protein Amet_3339 4 None None None 150388901 Common - anthranilate phosphoribosyltransferase Amet_1079 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 150389350 Common - efflux transporter, RND family, MFP subunit Amet_1556 154 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150391602 Common - binding-protein-dependent transport systems inner membrane component Amet_3893 117 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 150391791 Common - NADH dehydrogenase (quinone) Amet_4100 188 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150392041 Nonpathogen - hypothetical protein Amet_4357 1 None None None 150391593 Common - MATE efflux family protein Amet_3876 190 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150390972 Common - Citrate (pro-3S)-lyase Amet_3224 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 150388469 Common - hypothetical protein Amet_0633 2 None None None 150391361 Common - protein of unknown function DUF503 Amet_3629 40 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 150389496 Common - GTP-binding protein TypA Amet_1710 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 150391532 Common - response regulator receiver and SARP domain protein Amet_3804 186 COG3947 COG3947, Response regulator containing CheY-like receiver and SARP domains Signal transduction mechanisms 150391628 Common - helix-turn-helix- domain containing protein, AraC type Amet_3923 18 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 150389104 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_1289 63 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150390318 Nonpathogen - hypothetical protein Amet_2556 1 None None None 150388345 Common - hypothetical protein Amet_0508 7 None None None 150390166 Nonpathogen - hypothetical protein Amet_2402 1 None None None 150389433 Common - periplasmic solute binding protein Amet_1646 145 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150390716 Common - NAD/NADP octopine/nopaline dehydrogenase Amet_2956 31 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 150388094 Common - ethanolamine utilization protein, EutP Amet_0251 19 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 150389474 Common - ABC transporter related Amet_1688 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390113 Common - protein-export membrane protein SecF Amet_2349 220 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 150391690 Nonpathogen - hypothetical protein Amet_3998 1 None None None 150388193 Common - F0F1 ATP synthase subunit beta Amet_0353 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 150389210 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Amet_1400 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 150390806 Common - ribosomal protein S20 Amet_3056 187 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 150390582 Common - ATPase AAA-2 domain protein Amet_2822 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150388148 Common - GtrA family protein Amet_0307 16 COG2246 COG2246, Predicted membrane protein Function unknown 150388329 Common - peptidase S26B, signal peptidase Amet_0492 18 None None None 150389842 Common - transcriptional regulator, MarR family Amet_2072 120 COG1846 MarR, Transcriptional regulators Transcription 150390148 Nonpathogen - hypothetical protein Amet_2384 1 None None None 150388712 Nonpathogen - hypothetical protein Amet_0880 1 None None None 150390893 Common - putative CheW protein Amet_3144 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150392396 Common - ABC transporter related Amet_4718 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388870 Common - IstB domain protein ATP-binding protein Amet_1045 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150388116 Nonpathogen - hypothetical protein Amet_0273 1 None None None 150388929 Nonpathogen - hypothetical protein Amet_1108 1 None None None 150390250 Nonpathogen - hypothetical protein Amet_2487 11 None None None 150391636 Common - putative transcriptional regulator, MerR family Amet_3935 50 COG0789 SoxR, Predicted transcriptional regulators Transcription 150388307 Common - molybdopterin dehydrogenase, FAD-binding Amet_0470 36 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 150392375 Nonpathogen - hypothetical protein Amet_4697 1 None None None 150388589 Nonpathogen - hypothetical protein Amet_0754 1 None None None 150391694 Nonpathogen - hypothetical protein Amet_4002 1 None None None 150391992 Common - butyrate kinase Amet_4308 145 COG3426 COG3426, Butyrate kinase Energy production and conversion 150390375 Common - helix-turn-helix domain protein Amet_2613 26 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150388121 Common - putative small multi-drug export Amet_0278 19 COG2426 COG2426, Predicted membrane protein Function unknown 150390680 Common - Nitrite reductase (cytochrome; ammonia-forming) Amet_2920 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 150391882 Common - ATPase, BadF/BadG/BcrA/BcrD type Amet_4191 61 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 150390140 Nonpathogen - hypothetical protein Amet_2376 3 None None None 150388743 Common - BFD domain protein (2Fe-2S)-binding domain protein Amet_0912 21 None None None 150389527 Nonpathogen - hypothetical protein Amet_1742 1 None None None 150390577 Common - histidine kinase internal region Amet_2817 121 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150389024 Common - tRNA (guanine-N(7)-)-methyltransferase Amet_1206 171 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 150388234 Nonpathogen - hypothetical protein Amet_0396 1 None None None 150388314 Common - Membrane dipeptidase Amet_0477 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 150390788 Common - protein of unknown function DUF107 Amet_3038 74 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 150389046 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Amet_1228 50 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 150390632 Common - peptidase U4, sporulation factor SpoIIGA Amet_2872 15 None None None 150388076 Common - TRAP transporter, 4TM/12TM fusion protein Amet_0231 93 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 150392140 Common - preprotein translocase, SecY subunit Amet_4458 240 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 150391009 Common - isoprenylcysteine carboxyl methyltransferase Amet_3261 51 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 150388041 Common - regulatory protein, MarR Amet_0194 14 COG1497 COG1497, Predicted transcriptional regulator Transcription 150392039 Common - hypothetical protein Amet_4355 10 None None None 150389463 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Amet_1676 112 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150389694 Common - bacitracin ABC transporter, permease protein Amet_1920 10 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 150390293 Common - peptidase M50 Amet_2530 105 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 150391641 Nonpathogen - hypothetical protein Amet_3940 2 None None None 150388075 Common - TRAP transporter solute receptor, TAXI family Amet_0230 45 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 150388411 Common - Imidazoleglycerol-phosphate dehydratase Amet_0574 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 150388407 Common - Histidine--tRNA ligase Amet_0570 249 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 150389924 Common - MscS Mechanosensitive ion channel Amet_2155 59 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150388855 Nonpathogen - hypothetical protein Amet_1028 2 None None None 150391246 Common - OsmC family protein Amet_3509 33 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 150390982 Nonpathogen - hypothetical protein Amet_3234 1 None None None 150387988 Common - hypothetical protein Amet_0139 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 150391182 Common - oxidoreductase domain protein Amet_3444 196 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150391555 Common - Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Amet_3828 124 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150391627 Common - hypothetical protein Amet_3922 18 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 150390683 Common - hypothetical protein Amet_2923 9 None None None 150391762 Nonpathogen - hypothetical protein Amet_4070 10 None None None 150390384 Common - peptidase M42 family protein Amet_2622 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 150389833 Common - binding-protein-dependent transport systems inner membrane component Amet_2062 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390791 Common - GatB/Yqey domain protein Amet_3041 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 150388009 Common - transcriptional regulator, AbrB family Amet_0162 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150388171 Common prfA peptide chain release factor 1 Amet_0331 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 150390499 Common - lysine 2,3-aminomutase YodO family protein Amet_2738 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 150388803 Common - MgtC/SapB transporter Amet_0976 120 COG1285 SapB, Uncharacterized membrane protein Function unknown 150388986 Common - diguanylate cyclase Amet_1167 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150390331 Common - hypothetical protein Amet_2569 2 None None None 150390172 Common - YqaS Amet_2408 4 COG5484 COG5484, Uncharacterized conserved protein Function unknown 150388381 Common - helix-turn-helix- domain containing protein, AraC type Amet_0544 141 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150389980 Common - anti-sigma-factor antagonist Amet_2212 58 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 150390481 Common - flagellar hook-length control protein Amet_2719 24 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 150391190 Common - glycosyl transferase, group 1 Amet_3452 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150390175 Common - phage Terminase Amet_2411 42 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 150389379 Common - 40-residue YVTN family beta-propeller repeat protein Amet_1590 66 COG3391 COG3391, Uncharacterized conserved protein Function unknown 150388597 Common - C_GCAxxG_C_C family protein Amet_0762 2 None None None 150390653 Nonpathogen - hypothetical protein Amet_2893 1 None None None 150390882 Common - helix-turn-helix domain protein Amet_3133 11 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150391054 Common - protein of unknown function DUF624 Amet_3316 9 COG5578 COG5578, Predicted integral membrane protein Function unknown 150389963 Common - CRISPR-associated protein Cas4 Amet_2194 35 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 150391935 Common - 3-oxoacid CoA-transferase, A subunit Amet_4247 93 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 150388364 Common - metal dependent phosphohydrolase Amet_0527 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150390161 Common - phage replication protein Amet_2397 5 None None None 150391512 Common - Mannitol dehydrogenase, C-terminal domain Amet_3783 76 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150388030 Common - CTP synthetase Amet_0183 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 150389293 Nonpathogen - hypothetical protein Amet_1487 1 None None None 150391078 Nonpathogen - hypothetical protein Amet_3340 4 None None None 150389932 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Amet_2163 198 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 150389370 Common - helix-turn-helix domain protein Amet_1581 2 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150392446 Common - phosphoesterase, RecJ domain protein Amet_4770 90 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 150390308 Common - tRNA-i(6)A37 thiotransferase enzyme MiaB Amet_2545 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150390679 Common - ResB protein required for cytochrome c biosynthesis-like protein Amet_2919 30 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 150389592 Common - peptidase M23B Amet_1812 36 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150390281 Common - glycosyl transferase, family 2 Amet_2518 103 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150387880 Common - SirA family protein Amet_0027 32 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 150388048 Common - glycosyl transferase, group 1 Amet_0203 184 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150391333 Common - uncharacterized conserved protein, repeat-containing protein Amet_3601 7 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 150391771 Nonpathogen - hypothetical protein Amet_4079 1 None None None 150391738 Common - phage-associated helicase Amet_4046 99 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150388676 Common - prophage antirepressor Amet_0841 42 COG3617 COG3617, Prophage antirepressor Transcription 150387890 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Amet_0037 146 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 150389164 Common - glycine cleavage system T protein Amet_1354 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 150391221 Common - diguanylate cyclase and metal dependent phosphohydrolase Amet_3483 191 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150388877 Common - Abortive infection protein Amet_1054 4 None None None 150390082 Common - YheO domain protein Amet_2315 47 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 150388595 Common - nitroreductase Amet_0760 137 COG0778 NfnB, Nitroreductase Energy production and conversion 150390545 Common - methionyl-tRNA formyltransferase Amet_2785 225 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 150391299 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_3567 55 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150392030 Common - hypothetical protein Amet_4346 3 None None None 150390713 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Amet_2953 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 150388883 Nonpathogen - hypothetical protein Amet_1061 1 None None None 150388388 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_0551 80 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150391376 Common - putative signal-transduction protein with CBS domains Amet_3644 195 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 150388535 Common - sigma54 specific transcriptional regulator, Fis family Amet_0700 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150388578 Common - hypothetical protein Amet_0743 21 None None None 150392302 Common - phosphate ABC transporter, ATPase subunit Amet_4621 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 150387854 Common dnaA chromosomal replication initiation protein Amet_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 150390214 Common - SCP-like extracellular protein Amet_2450 56 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150391086 Common - DNA topoisomerase III Amet_3348 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150390416 Common - transcriptional regulator, PadR-like family Amet_2654 26 COG1695 COG1695, Predicted transcriptional regulators Transcription 150390915 Common - PHP C-terminal domain protein Amet_3166 80 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 150389380 Common - hypothetical protein Amet_1591 4 None None None 150390192 Nonpathogen - hypothetical protein Amet_2428 2 None None None 150390943 Common - Tetrahydrodipicolinate succinyltransferase N-terminal domain protein Amet_3195 153 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 150388904 Common - tryptophan synthase subunit beta Amet_1082 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 150391596 Nonpathogen - hypothetical protein Amet_3884 2 None None None 150388669 Common - chaperonin GroEL Amet_0834 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 150388322 Common - succinyl-CoA synthetase subunit alpha Amet_0485 208 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 150391974 Common - metal dependent phosphohydrolase Amet_4288 65 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150390905 Common - hypothetical protein Amet_3156 3 None None None 150391375 Common - phosphoribulokinase/uridine kinase Amet_3643 148 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 150390994 Common - magnesium transporter Amet_3246 178 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 150389809 Common - binding-protein-dependent transport systems inner membrane component Amet_2037 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390255 Common - Sporulation stage III, protein AA Amet_2492 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 150389996 Common - NUDIX hydrolase Amet_2228 7 None None None 150392078 Common - hypothetical protein Amet_4395 3 None None None 150388016 Common - YabP family protein Amet_0169 15 None None None 150388392 Common - altronate oxidoreductase Amet_0555 87 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150391134 Common - Auxin Efflux Carrier Amet_3396 107 COG0679 COG0679, Predicted permeases General function prediction only 150391940 Common - polysaccharide deacetylase Amet_4252 133 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150390870 Nonpathogen - hypothetical protein Amet_3121 1 COG2378 COG2378, Predicted transcriptional regulator Transcription 150391072 Common - branched-chain amino acid aminotransferase Amet_3334 202 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150391526 Common - Monosaccharide-transporting ATPase Amet_3797 110 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 150388053 Common - UDP-glucose/GDP-mannose dehydrogenase Amet_0208 66 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 150389412 Common - small, acid-soluble spore protein, alpha/beta family Amet_1625 7 None None None 150392363 Common - IstB domain protein ATP-binding protein Amet_4685 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150390153 Nonpathogen - transcriptional regulator, XRE family Amet_2389 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 150388296 Common - Monosaccharide-transporting ATPase Amet_0458 166 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 150388068 Nonpathogen - hypothetical protein Amet_0223 1 COG1316 LytR, Transcriptional regulator Transcription 150390092 Common - two component transcriptional regulator, winged helix family Amet_2325 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150389112 Common - hypothetical protein Amet_1297 42 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 150391899 Common - oxidoreductase FAD/NAD(P)-binding domain protein Amet_4209 95 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150390068 Common - hypothetical protein Amet_2301 43 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 150390979 Nonpathogen - hypothetical protein Amet_3231 1 None None None 150392272 Common - D-alanine--D-alanine ligase Amet_4591 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150389368 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_1579 39 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150392282 Nonpathogen - hypothetical protein Amet_4601 1 None None None 150388183 Common - UDP-N-acetylglucosamine 2-epimerase Amet_0343 156 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 150390931 Common - Fe-S cluster domain protein Amet_3183 36 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150389172 Common - hypothetical protein Amet_1362 2 None None None 150391039 Common - protein of unknown function DUF224, cysteine-rich region domain protein Amet_3298 60 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 150389190 Common - carbon starvation protein CstA Amet_1380 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 150390004 Nonpathogen - hypothetical protein Amet_2236 1 None None None 150388421 Common - Formate C-acetyltransferase Amet_0584 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150392010 Common - glutaredoxin Amet_4326 82 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 150389678 Common - major facilitator superfamily MFS_1 Amet_1904 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150390200 Nonpathogen - hypothetical protein Amet_2436 1 None None None 150391002 Common - prolipoprotein diacylglyceryl transferase Amet_3254 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150387941 Common - hypothetical protein Amet_0088 11 None None None 150391950 Common - putative ribonuclease BN Amet_4262 76 COG1295 Rbn, Predicted membrane protein Function unknown 150389408 Common - hypoxanthine phosphoribosyltransferase Amet_1621 154 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 150390440 Common - DNA polymerase III, alpha subunit Amet_2678 220 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 150388561 Common - hypothetical protein Amet_0726 11 None None None 150391775 Nonpathogen - Accessory gene regulator B Amet_4083 2 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150390490 Common - flagellar basal-body rod protein FlgB Amet_2728 21 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 150390847 Nonpathogen - hypothetical protein Amet_3097 1 None None None 150392387 Common - protein of unknown function DUF395, YeeE/YedE Amet_4709 51 None None None 150387877 Common - seryl-tRNA synthetase Amet_0024 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 150390563 Common - protein of unknown function DUF552 Amet_2803 55 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 150390508 Common - signal recognition particle protein Amet_2747 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 150390227 Common - protein of unknown function DUF1292 Amet_2463 18 None None None 150389310 Common - two component transcriptional regulator, winged helix family Amet_1506 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150392178 Common - protein of unknown function DUF901 Amet_4496 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 150389257 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Amet_1448 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150391214 Nonpathogen - hypothetical protein Amet_3476 2 None None None 150388192 Common - ATP synthase F1, gamma subunit Amet_0352 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 150391255 Common - Nitrogenase Amet_3518 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150389876 Nonpathogen - hypothetical protein Amet_2106 2 None None None 150390543 Common - peptidase, membrane zinc metallopeptidase, putative Amet_2783 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 150389207 Nonpathogen - hypothetical protein Amet_1397 1 None None None 150388652 Common - L-lactate transport Amet_0817 104 COG1620 LldP, L-lactate permease Energy production and conversion 150391673 Common - hypothetical protein Amet_3978 3 None None None 150388249 Nonpathogen - hypothetical protein Amet_0411 1 None None None 150389643 Nonpathogen - hypothetical protein Amet_1867 1 None None None 150391769 Nonpathogen - hypothetical protein Amet_4077 1 None None None 150390757 Common tnaA tryptophanase Amet_3003 44 COG3033 TnaA, Tryptophanase Amino acid transport and metabolism 150391004 Common - integral membrane sensor signal transduction histidine kinase Amet_3256 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150392334 Nonpathogen - hypothetical protein Amet_4654 1 None None None 150389260 Common - ABC transporter related Amet_1451 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150390964 Common - sodium ion-translocating decarboxylase, beta subunit Amet_3216 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 150390737 Common - two component, sigma54 specific, transcriptional regulator, Fis family Amet_2978 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150390850 Common - hypothetical protein Amet_3100 2 None None None 150387863 Common - phage transcriptional regulator, RinA family Amet_0010 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150392380 Nonpathogen - hypothetical protein Amet_4702 6 None None None 150392471 Common - methyltransferase GidB Amet_4795 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 150391807 Common - ABC transporter related Amet_4116 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150388375 Common - hypothetical protein Amet_0538 29 COG3875 COG3875, Uncharacterized conserved protein Function unknown 150390501 Common - Ribonuclease H Amet_2740 237 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 150392005 Common - Sporulation protein YtaF Amet_4321 20 COG1971 COG1971, Predicted membrane protein Function unknown 150391018 Common - Heavy metal transport/detoxification protein Amet_3271 82 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150392275 Nonpathogen - hypothetical protein Amet_4594 2 None None None 150388928 Common - protein of unknown function DUF112, transmembrane Amet_1107 79 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 150387955 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_0102 92 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150389764 Common - hypothetical protein Amet_1991 71 COG1432 COG1432, Uncharacterized conserved protein Function unknown 150391232 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_3494 48 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150390073 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_2306 4 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150389196 Nonpathogen - hypothetical protein Amet_1386 1 None None None 150391501 Common - transport system permease protein Amet_3772 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150391484 Common - DEAD/DEAH box helicase domain protein Amet_3755 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150391037 Common - CDP-alcohol phosphatidyltransferase Amet_3296 28 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 150388590 Common - DNA polymerase, beta domain protein region Amet_0755 15 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 150390099 Common - hypothetical protein Amet_2335 2 None None None 150390014 Nonpathogen - hypothetical protein Amet_2246 1 None None None 150389849 Common - protein of unknown function UPF0061 Amet_2079 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 150389143 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1331 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 150389509 Nonpathogen - hypothetical protein Amet_1723 1 None None None 150390061 Common - septum site-determining protein MinC Amet_2294 41 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 150392459 Nonpathogen - hypothetical protein Amet_4783 2 None None None 150389279 Common - Integrase, catalytic region Amet_1471 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150390236 Common - uridine kinase Amet_2472 83 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 150388104 Common - cobalamin adenosyltransferase Amet_0261 12 COG4812 EutT, Ethanolamine utilization cobalamin adenosyltransferase Amino acid transport and metabolism 150389239 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1430 6 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 150390594 Nonpathogen - hypothetical protein Amet_2834 1 None None None 150389187 Common - signal transduction histidine kinase, LytS Amet_1377 107 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150391422 Common - peptide chain release factor 3 Amet_3692 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 150390841 Common - acyl-CoA dehydrogenase domain protein Amet_3091 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150392051 Common - NusG antitermination factor Amet_4367 188 COG0250 NusG, Transcription antiterminator Transcription 150388002 Common - SpoVG family protein Amet_0155 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 150391268 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_3532 74 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150390357 Nonpathogen - hypothetical protein Amet_2595 1 None None None 150391651 Common - protein of unknown function DUF214 Amet_3953 17 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 150389880 Nonpathogen - hypothetical protein Amet_2111 2 None None None 150391871 Common - Rubrerythrin Amet_4180 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 150391098 Common - Resolvase, N-terminal domain Amet_3360 46 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150389958 Common - CRISPR-associated protein Cas6 Amet_2189 8 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 150390694 Common - methyl-accepting chemotaxis sensory transducer Amet_2934 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150392207 Common - transcription elongation factor GreA Amet_4525 204 COG0782 GreA, Transcription elongation factor Transcription 150389795 Common - dihydrolipoamide dehydrogenase Amet_2023 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 150391458 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_3728 42 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150391592 Common - transcriptional regulator, LysR family Amet_3875 180 COG0583 LysR, Transcriptional regulator Transcription 150389893 Nonpathogen - hypothetical protein Amet_2124 1 None None None 150392245 Common - protein of unknown function DUF182 Amet_4564 120 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 150388703 Nonpathogen - hypothetical protein Amet_0868 1 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 150389538 Common - von Willebrand factor, type A Amet_1755 86 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 150390136 Common - methylaspartate mutase Amet_2372 23 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150388213 Common - protein of unknown function DUF1568 Amet_0373 51 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150390323 Common - hypothetical protein Amet_2561 2 None None None 150392102 Common - 7TM domain sensor diguanylate cyclase Amet_4420 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 150388963 Common - cation antiporter Amet_1142 22 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 150389680 Nonpathogen - hypothetical protein Amet_1906 1 None None None 150390024 Nonpathogen - hypothetical protein Amet_2256 2 None None None 150392346 Common - sigma54 specific transcriptional regulator, Fis family Amet_4666 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150391317 Common - ABC transporter related Amet_3585 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 150389689 Common - two component transcriptional regulator, winged helix family Amet_1915 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391684 Common - replication initiator A domain protein Amet_3992 8 None None None 150391892 Common - two component transcriptional regulator, LuxR family Amet_4202 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150392101 Common - cyclase family protein Amet_4419 56 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 150389073 Common - transcriptional antiterminator, BglG Amet_1257 29 COG3711 BglG, Transcriptional antiterminator Transcription 150388938 Common - binding-protein-dependent transport systems inner membrane component Amet_1117 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391631 Nonpathogen - hypothetical protein Amet_3928 1 None None None 150389035 Common - Haloacid dehalogenase domain protein hydrolase Amet_1217 12 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150390907 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_3158 107 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 150389234 Nonpathogen - hypothetical protein Amet_1425 1 None None None 150391723 Nonpathogen - hypothetical protein Amet_4031 1 None None None 150390312 Common - conserved hypothetical protein, CF-8 family Amet_2549 2 None None None 150392317 Common - Glutamate--cysteine ligase Amet_4636 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 150392463 Common - diacylglycerol kinase, catalytic region Amet_4787 122 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 150391173 Common - hypothetical protein Amet_3435 6 None None None 150391383 Common - hypothetical protein Amet_3651 37 COG2339 COG2339, Predicted membrane protein Function unknown 150389806 Common - hypothetical protein Amet_2034 6 COG1532 COG1532, Predicted RNA-binding protein General function prediction only 150389887 Common - hypothetical protein Amet_2118 10 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150390857 Common - DNA gyrase, subunit B domain protein Amet_3107 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 150391049 Common - potassium uptake protein, TrkH family Amet_3310 103 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 150389991 Common - penicillin-binding protein, 1A family Amet_2223 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 150390122 Common hisS histidyl-tRNA synthetase Amet_2358 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150391042 Common - hypothetical protein Amet_3301 61 COG3943 COG3943, Virulence protein General function prediction only 150391889 Nonpathogen - hypothetical protein Amet_4199 1 None None None 150389735 Nonpathogen - hypothetical protein Amet_1962 1 None None None 150389782 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2009 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150391029 Nonpathogen - hypothetical protein Amet_3284 1 None None None 150388363 Common - hypothetical protein Amet_0526 3 None None None 150389197 Common - anaerobic ribonucleoside triphosphate reductase Amet_1387 127 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 150388944 Common - Succinylglutamate desuccinylase/aspartoacylase Amet_1123 53 COG3608 COG3608, Predicted deacylase General function prediction only 150388852 Nonpathogen - hypothetical protein Amet_1025 1 None None None 150390399 Nonpathogen - hypothetical protein Amet_2637 4 None None None 150390682 Common - Acetamidase/Formamidase Amet_2922 66 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 150390108 Common - hypothetical protein Amet_2344 2 COG1289 COG1289, Predicted membrane protein Function unknown 150390689 Nonpathogen - hypothetical protein Amet_2929 4 None None None 150391465 Common - Redoxin domain protein Amet_3736 96 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150389025 Nonpathogen - hypothetical protein Amet_1207 1 None None None 150388969 Common - NADH-ubiquinone oxidoreductase, chain 4L Amet_1148 9 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 150391782 Common - protein of unknown function UPF0052 and CofD Amet_4091 94 COG0391 COG0391, Uncharacterized conserved protein Function unknown 150388444 Common - Xanthine dehydrogenase Amet_0607 117 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150389228 Common - beta-lactamase domain protein Amet_1418 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 150390796 Common prmA ribosomal protein L11 methyltransferase Amet_3046 179 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 150389724 Common - NusG antitermination factor Amet_1951 188 COG0250 NusG, Transcription antiterminator Transcription 150392325 Common - sigma54 specific transcriptional regulator, Fis family Amet_4644 179 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150389056 Common - FMN-binding domain protein Amet_1239 9 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 150388416 Common - pyruvate carboxylase Amet_0579 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 150391451 Common - C4-dicarboxylate transporter/malic acid transport protein Amet_3721 18 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 150388792 Common - transposase IS200-family protein Amet_0965 71 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389904 Nonpathogen - hypothetical protein Amet_2135 1 None None None 150391997 Common - protein of unknown function DUF147 Amet_4313 68 COG1624 COG1624, Uncharacterized conserved protein Function unknown 150389085 Common - glutamine synthetase, catalytic region Amet_1269 221 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 150391143 Common - Collagen triple helix repeat Amet_3405 4 COG5180 PBP1, Protein interacting with poly(A)-binding protein RNA processing and modification 150387942 Nonpathogen - hypothetical protein Amet_0089 1 None None None 150391951 Common - amidohydrolase 2 Amet_4263 30 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 150391411 Common - hypothetical protein Amet_3681 2 None None None 150387899 Common - aminodeoxychorismate lyase Amet_0046 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 150389852 Common - transcriptional regulator, XRE family Amet_2082 55 COG1476 COG1476, Predicted transcriptional regulators Transcription 150389002 Common - hydrolase, HAD-superfamily, subfamily IIIA Amet_1184 129 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 150392183 Common - cysteinyl-tRNA synthetase Amet_4501 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150388605 Common - putative metal dependent phosphohydrolase Amet_0770 90 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150388149 Common - hypothetical protein Amet_0308 14 COG5036 COG5036, SPX domain-containing protein involved in vacuolar polyphosphate accumulation Inorganic ion transport and metabolism 150392235 Common - alcohol dehydrogenase, zinc-containing, putative Amet_4553 17 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150388376 Common - Uncharacterized membrane protein Amet_0539 14 COG3949 COG3949, Uncharacterized membrane protein Function unknown 150390003 Common - protein of unknown function DUF28 Amet_2235 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 150391055 Common - Alpha-N-arabinofuranosidase Amet_3317 40 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 150388756 Common - phosphoribosylamine--glycine ligase Amet_0926 235 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 150389857 Nonpathogen - hypothetical protein Amet_2087 6 None None None 150392216 Common - biotin--acetyl-CoA-carboxylase ligase Amet_4534 214 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 150390461 Common - response regulator receiver modulated CheB methylesterase Amet_2699 220 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 150389748 Common - hypothetical protein Amet_1975 3 None None None 150390511 Common - chromosome segregation protein SMC Amet_2750 224 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150389382 Common - phage integrase family protein Amet_1593 201 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150391927 Common - thiamine biosynthesis protein ThiS Amet_4237 49 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 150387879 Common - CMP/dCMP deaminase, zinc-binding Amet_0026 219 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 150388265 Common - hypothetical protein Amet_0427 5 None None None 150389823 Nonpathogen - hypothetical protein Amet_2052 2 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150392366 Nonpathogen - hypothetical protein Amet_4688 1 None None None 150389756 Common - NADPH-dependent FMN reductase Amet_1983 106 COG0431 COG0431, Predicted flavoprotein General function prediction only 150391831 Common - polysaccharide pyruvyl transferase Amet_4140 49 COG2327 WcaK, Uncharacterized conserved protein Function unknown 150392260 Nonpathogen - hypothetical protein Amet_4579 1 None None None 150390317 Nonpathogen - hypothetical protein Amet_2555 1 None None None 150389970 Common - UvrD/REP helicase Amet_2202 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150390934 Common - NQR2 and RnfD family protein Amet_3186 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 150390779 Common - protein of unknown function DUF502 Amet_3029 84 COG2928 COG2928, Uncharacterized conserved protein Function unknown 150392284 Common - transcriptional regulator, GntR family Amet_4603 142 COG1802 GntR, Transcriptional regulators Transcription 150389405 Common - UDP-N-acetylmuramyl-tripeptide synthetase Amet_1618 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150392232 Common - DNA mismatch repair protein MutS domain protein Amet_4550 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150391304 Common - ribonuclease R Amet_3572 203 COG0557 VacB, Exoribonuclease R Transcription 150387937 Common - DNA polymerase III, delta prime subunit Amet_0084 234 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 150388808 Common - regulatory protein, ArsR Amet_0981 185 COG0640 ArsR, Predicted transcriptional regulators Transcription 150389530 Common - transcriptional repressor, LexA family Amet_1746 29 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150390525 Common - protein of unknown function DUF795 Amet_2764 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 150391653 Common - integral membrane sensor signal transduction histidine kinase Amet_3955 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391705 Common - rRNA biogenesis protein rrp5, putative Amet_4013 8 None None None 150390464 Common - GTP-binding signal recognition particle SRP54, G- domain Amet_2702 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 150390548 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Amet_2788 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 150388423 Common - periplasmic binding protein/LacI transcriptional regulator Amet_0586 130 COG1609 PurR, Transcriptional regulators Transcription 150391294 Nonpathogen - hypothetical protein Amet_3562 1 None None None 150389448 Common - Indolepyruvate ferredoxin oxidoreductase Amet_1661 114 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 150390872 Common - Lytic transglycosylase, catalytic Amet_3123 175 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150391577 Common - beta-lactamase domain protein Amet_3852 33 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150389248 Nonpathogen - catalytic domain of components of various dehydrogenase complexes Amet_1439 2 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 150390816 Nonpathogen - hypothetical protein Amet_3066 1 None None None 150388044 Nonpathogen - hypothetical protein Amet_0199 1 None None None 150388992 Common - ABC-3 protein Amet_1174 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 150388404 Common - threonine synthase Amet_0567 227 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 150388956 Common - ABC transporter related Amet_1135 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150389319 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_1515 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150391184 Common - hypothetical protein Amet_3446 6 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 150391713 Common - hypothetical protein Amet_4021 6 None None None 150391916 Common - protein of unknown function DUF421 Amet_4226 66 COG2323 COG2323, Predicted membrane protein Function unknown 150389353 Common - two component transcriptional regulator, LuxR family Amet_1559 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150390620 Nonpathogen - hypothetical protein Amet_2860 1 None None None 150391965 Nonpathogen - hypothetical protein Amet_4277 7 None None None 150390023 Nonpathogen - hypothetical protein Amet_2255 1 None None None 150390273 Common argR arginine repressor Amet_2510 47 COG1438 ArgR, Arginine repressor Transcription 150391780 Nonpathogen - protein of unknown function DUF1540 Amet_4089 2 None None None 150388337 Common - Transcriptional regulator IclR-like protein Amet_0500 117 COG1414 IclR, Transcriptional regulator Transcription 150389420 Common - translation initiation factor IF-3 Amet_1633 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 150390159 Nonpathogen - hypothetical protein Amet_2395 1 None None None 150389344 Common - hypothetical protein Amet_1548 12 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 150391262 Nonpathogen - hypothetical protein Amet_3525 1 None None None 150391275 Common - peptidase M28 Amet_3539 84 COG2234 Iap, Predicted aminopeptidases General function prediction only 150388563 Common - flagellar hook-associated protein 3 Amet_0728 105 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 150388359 Nonpathogen - hypothetical protein Amet_0522 3 None None None 150388448 Common - flagellar motor switch protein FliM Amet_0612 110 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 150391321 Common - Glycine reductase Amet_3589 12 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 150391787 Common - molybdenum cofactor biosynthesis protein A Amet_4096 206 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 150391990 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_4306 58 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 150388821 Common - twin-arginine translocation protein, TatA/E family subunit Amet_0994 20 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 150389862 Common - methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase Amet_2092 161 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150388878 Common - hypothetical protein Amet_1055 35 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150390021 Common - transposase Amet_2253 6 None None None 150389658 Common - amidohydrolase Amet_1883 26 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 150389067 Common - Pyruvate dehydrogenase (acetyl-transferring) Amet_1251 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 150390670 Nonpathogen - hypothetical protein Amet_2910 1 None None None 150388168 Nonpathogen - hypothetical protein Amet_0328 1 None None None 150389881 Nonpathogen - hypothetical protein Amet_2112 1 None None None 150391966 Common - NUDIX hydrolase Amet_4278 7 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150388027 Nonpathogen - Fibronectin, type III domain protein Amet_0180 7 None None None 150391544 Common - transposase, IS605 OrfB family Amet_3816 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 150391971 Common - hypothetical protein Amet_4284 2 None None None 150389977 Common - membrane protein of unknown function Amet_2209 49 COG1950 COG1950, Predicted membrane protein Function unknown 150389556 Nonpathogen - hypothetical protein Amet_1774 1 None None None 150390434 Common - ribosome-binding factor A Amet_2672 186 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 150388624 Nonpathogen - hypothetical protein Amet_0789 3 None None None 150391213 Common - peptidase A24A domain protein Amet_3475 119 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150390783 Common - PhoH family protein Amet_3033 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 150390198 Nonpathogen - hypothetical protein Amet_2434 1 None None None 150390120 Nonpathogen - hypothetical protein Amet_2356 1 None None None 150388751 Common - phosphoribosylformylglycinamidine synthase II Amet_0921 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 150389571 Nonpathogen - hypothetical protein Amet_1790 1 None None None 150390261 Common - Sporulation stage III, protein AG Amet_2498 15 None None None 150388623 Common - sigma 54 modulation protein/ribosomal protein S30EA Amet_0788 162 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 150391150 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit Amet_3412 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 150388698 Common - Peptidase M15A Amet_0863 47 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 150389626 Common - ABC transporter related Amet_1846 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150391660 Nonpathogen - hypothetical protein Amet_3963 1 None None None 150387972 Nonpathogen - hypothetical protein Amet_0122 1 None None None 150390989 Common - biotin synthase Amet_3241 184 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 150387926 Common - precorrin-2 C20-methyltransferase Amet_0073 124 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 150392149 Common - ribosomal protein L24 Amet_4467 202 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 150389476 Common - conserved hypothetical protein 1655 Amet_1690 6 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 150392080 Nonpathogen - hypothetical protein Amet_4397 1 None None None 150389115 Nonpathogen - hypothetical protein Amet_1300 2 None None None 150391604 Common - transposase Amet_3895 41 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388641 Common - ABC-type antimicrobial peptide transport system ATPase component-like protein Amet_0806 34 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390863 Common ileS isoleucyl-tRNA synthetase Amet_3114 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150388745 Common - copper amine oxidase domain protein Amet_0914 14 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 150391879 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Amet_4188 29 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150392221 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_4539 144 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150388177 Common - protein tyrosine phosphatase Amet_0337 101 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 150391362 Common - acriflavin resistance protein Amet_3630 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150392433 Common - multi-sensor signal transduction histidine kinase Amet_4757 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150389180 Common - Collagen triple helix repeat Amet_1370 3 None None None 150389332 Common - hypothetical protein Amet_1530 22 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 150388949 Common - ABC transporter related Amet_1128 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150389459 Common - RDD domain containing protein Amet_1672 18 COG1714 COG1714, Predicted membrane protein/domain Function unknown 150391863 Common - ABC transporter related Amet_4172 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390665 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2905 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388902 Common - Indole-3-glycerol-phosphate synthase Amet_1080 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 150388497 Common - Radical SAM domain protein Amet_0662 25 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 150390803 Nonpathogen - hypothetical protein Amet_3053 1 None None None 150391105 Common - GCN5-related N-acetyltransferase Amet_3367 86 COG3153 COG3153, Predicted acetyltransferase General function prediction only 150391116 Common - carbamoyl-phosphate synthase, large subunit Amet_3378 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 150389198 Common - anaerobic ribonucleoside-triphosphate reductase activating protein Amet_1388 90 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150391584 Nonpathogen - hypothetical protein Amet_3861 1 None None None 150388985 Common - metal dependent phosphohydrolase Amet_1165 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150391516 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_3787 3 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150388547 Common - Lytic transglycosylase, catalytic Amet_0712 21 None None None 150388431 Common - Non-specific serine/threonine protein kinase Amet_0594 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150390222 Common alaS alanyl-tRNA synthetase Amet_2458 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150389062 Common - transposase, IS4 family protein Amet_1246 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150391984 Common - phosphoglucosamine mutase Amet_4300 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150387913 Common - porphobilinogen deaminase Amet_0060 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 150390835 Common - Uncharacterized protein UPF0065 Amet_3085 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 150391613 Nonpathogen - hypothetical protein Amet_3907 1 None None None 150387997 Common - peptidase T-like protein Amet_0148 131 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 150390607 Common - hypothetical protein Amet_2847 4 None None None 150388174 Common - cell cycle protein Amet_0334 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150392135 Common - ribosomal protein L36 Amet_4453 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 150391665 Common - Relaxase/mobilization nuclease family protein Amet_3969 14 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 150390899 Common - protein of unknown function UPF0180 Amet_3150 8 None None None 150388885 Common - oligoendopeptidase, pepF/M3 family Amet_1063 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 150391522 Common - protein of unknown function DUF1568 Amet_3793 56 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388468 Nonpathogen - hypothetical protein Amet_0632 1 None None None 150391629 Common - hypothetical protein Amet_3926 72 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150388391 Common - Alcohol dehydrogenase, zinc-binding domain protein Amet_0554 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150388691 Common - protein of unknown function DUF955 Amet_0856 24 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 150390242 Nonpathogen - hypothetical protein Amet_2478 3 None None None 150392439 Common - primosome, DnaD subunit Amet_4763 6 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150389583 Nonpathogen - hypothetical protein Amet_1803 3 None None None 150391823 Common - 5-formyltetrahydrofolate cyclo-ligase Amet_4132 110 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 150390627 Common - protein of unknown function DUF152 Amet_2867 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 150391126 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Amet_3388 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 150391792 Common - ferredoxin Amet_4101 23 COG3411 COG3411, Ferredoxin Energy production and conversion 150388577 Nonpathogen - hypothetical protein Amet_0742 2 None None None 150392112 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_4430 53 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150388571 Nonpathogen - hypothetical protein Amet_0736 1 None None None 150390295 Common - putative transcriptional regulator Amet_2532 161 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 150390613 Common - phage integrase family protein Amet_2853 202 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150391815 Common uvrC excinuclease ABC subunit C Amet_4124 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 150389686 Common - 3-demethylubiquinone-9 3-methyltransferase Amet_1912 66 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 150389778 Common - binding-protein-dependent transport systems inner membrane component Amet_2005 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390534 Common - ribosomal protein L28 Amet_2773 64 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 150390514 Common - Beta-ketoacyl synthase-like protein Amet_2753 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150392046 Common - hypothetical protein Amet_4362 2 None None None 150388127 Common - 2-alkenal reductase Amet_0285 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 150389107 Common - mannonate dehydratase Amet_1292 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 150391160 Common - hypothetical protein Amet_3422 3 COG0439 AccC, Biotin carboxylase Lipid metabolism 150387903 Common - putative transcriptional regulator, AsnC family Amet_0050 53 COG1522 Lrp, Transcriptional regulators Transcription 150388683 Common - N-6 DNA methylase Amet_0848 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150392386 Common - transcriptional regulator, LysR family Amet_4708 193 COG0583 LysR, Transcriptional regulator Transcription 150388346 Common - Pyridoxal-5'-phosphate-dependent protein, beta subunit Amet_0509 212 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150388102 Common - acetaldehyde dehydrogenase (acetylating) Amet_0259 195 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150390950 Common - GerA spore germination protein Amet_3202 15 None None None 150392229 Nonpathogen - hypothetical protein Amet_4547 1 None None None 150387949 Common - nucleoside recognition domain protein Amet_0096 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 150390751 Common - branched-chain amino acid transport Amet_2997 21 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 150390844 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Amet_3094 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150389363 Common - transcriptional regulator, XRE family Amet_1574 34 COG1396 HipB, Predicted transcriptional regulators Transcription 150390079 Common - Na+/Ca+ antiporter, CaCA family Amet_2312 134 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 150388835 Common - DNA binding domain, excisionase family Amet_1008 19 None None None 150388549 Nonpathogen - hypothetical protein Amet_0714 1 None None None 150389540 Common - Integrase, catalytic region Amet_1758 79 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388782 Common - AIR synthase related protein domain protein Amet_0952 191 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 150387872 Common - nicotinate-nucleotide pyrophosphorylase Amet_0019 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 150388019 Common - RNA binding S1 domain protein Amet_0172 214 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 150391498 Common - helicase c2 Amet_3769 132 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 150388509 Common - prolyl-tRNA synthetase Amet_0674 246 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150391903 Common - dihydroorotase, multifunctional complex type Amet_4213 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150389945 Common - ABC transporter, transmembrane region Amet_2176 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150391012 Nonpathogen - hypothetical protein Amet_3264 1 None None None 150391167 Common - hypothetical protein Amet_3429 5 None None None 150391019 Common - heavy metal translocating P-type ATPase Amet_3272 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150390404 Common - hypothetical protein Amet_2642 16 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150391722 Common - phage portal protein, HK97 family Amet_4030 70 COG4695 COG4695, Phage-related protein Function unknown 150389131 Common - Isocitrate dehydrogenase (NAD(+)) Amet_1319 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 150390458 Common - CheC, inhibitor of MCP methylation Amet_2696 33 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 150388973 Common - hypothetical protein Amet_1152 7 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 150389126 Common - transposase, IS4 family protein Amet_1312 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150391958 Common - transcriptional antiterminator, BglG Amet_4270 38 COG3711 BglG, Transcriptional antiterminator Transcription 150392399 Common - binding-protein-dependent transport systems inner membrane component Amet_4721 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150392161 Common - ribosomal protein S10 Amet_4479 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 150387855 Common - DNA polymerase III subunit beta Amet_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 150392423 Common - two component transcriptional regulator, winged helix family Amet_4747 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391809 Common - inner-membrane translocator Amet_4118 170 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 150389952 Common - penicillin-binding protein, 1A family Amet_2183 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 150392201 Common - Chloride channel, core Amet_4519 163 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 150390659 Common - protein serine phosphatase with GAF(s) sensor(s) Amet_2899 106 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150392087 Common - sodium/hydrogen exchanger Amet_4404 13 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 150388253 Common - phage uncharacterized protein Amet_0415 23 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 150389394 Common - type I restriction-modification system, M subunit Amet_1607 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150390851 Common - glycosyl transferase, family 2 Amet_3101 181 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150390182 Common - hypothetical protein Amet_2418 2 None None None 150388817 Common - molybdopterin oxidoreductase Amet_0990 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 150389914 Common - hypothetical protein Amet_2145 6 None None None 150390150 Common - protein of unknown function DUF955 Amet_2386 2 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 150392021 Common - diaminopimelate decarboxylase Amet_4337 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 150388235 Nonpathogen - hypothetical protein Amet_0397 1 None None None 150390888 Common - degV family protein Amet_3139 56 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150388995 Common - carbon-monoxide dehydrogenase, catalytic subunit Amet_1177 28 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150391477 Common - Electron transfer flavoprotein, alpha subunit-like protein Amet_3748 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150392195 Common - ATP:guanido phosphotransferase Amet_4513 26 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 150392294 Nonpathogen - hypothetical protein Amet_4613 5 None None None 150388474 Common - NADH dehydrogenase (quinone) Amet_0639 16 COG3411 COG3411, Ferredoxin Energy production and conversion 150389156 Common - Ferritin, Dps family protein Amet_1346 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 150388382 Common - MATE efflux family protein Amet_0545 50 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150391448 Nonpathogen - ABC-2 type transporter Amet_3718 2 None None None 150388058 Nonpathogen - hypothetical protein Amet_0213 1 None None None 150391418 Common - protein of unknown function DUF378 Amet_3688 25 COG2155 COG2155, Uncharacterized conserved protein Function unknown 150390571 Nonpathogen - hypothetical protein Amet_2811 1 None None None 150389157 Common - Cof-like hydrolase Amet_1347 130 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150389709 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Amet_1936 122 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150389488 Common - putative manganese-dependent inorganic pyrophosphatase Amet_1702 53 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 150389704 Common - transcriptional regulator/antitoxin, MazE Amet_1931 12 COG2336 MazE, Growth regulator Signal transduction mechanisms 150388776 Nonpathogen - FeoA family protein Amet_0946 2 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 150388864 Nonpathogen - hypothetical protein Amet_1038 2 None None None 150392151 Common - ribosomal protein S17 Amet_4469 223 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 150390477 Common - flagellar FlbD family protein Amet_2715 29 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 150389393 Nonpathogen - hypothetical protein Amet_1606 2 None None None 150389503 Nonpathogen - hypothetical protein Amet_1717 1 None None None 150388398 Common - Glycerophosphodiester phosphodiesterase Amet_0561 184 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 150390040 Nonpathogen - hypothetical protein Amet_2273 1 None None None 150388077 Common - plasmid pRiA4b ORF-3 family protein Amet_0232 40 None None None 150390776 Common - GTP-binding protein Era Amet_3026 232 COG1159 Era, GTPase General function prediction only 150391245 Nonpathogen - hypothetical protein Amet_3508 2 None None None 150389695 Common - plasmid maintenance system antidote protein, XRE family Amet_1921 4 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 150388248 Nonpathogen - hypothetical protein Amet_0410 1 None None None 150392274 Nonpathogen - hypothetical protein Amet_4593 5 None None None 150392362 Common - Integrase, catalytic region Amet_4684 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150391772 Common - IstB domain protein ATP-binding protein Amet_4080 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150389933 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Amet_2164 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150392202 Common - ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent Amet_4520 99 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 150391203 Nonpathogen - hypothetical protein Amet_3465 1 None None None 150391506 Common - methyl-accepting chemotaxis sensory transducer Amet_3777 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150389294 Nonpathogen - hypothetical protein Amet_1488 1 None None None 150388802 Common - protein of unknown function DUF1667 Amet_0975 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 150388596 Common - degV family protein Amet_0761 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150391097 Common - RNA-directed DNA polymerase (Reverse transcriptase) Amet_3359 87 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150392445 Common - ribosomal protein L9 Amet_4769 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 150388311 Common - hypothetical protein Amet_0474 4 None None None 150390419 Common - metal dependent phosphohydrolase Amet_2657 78 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150389186 Common - glutamate racemase Amet_1376 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 150390174 Nonpathogen - hypothetical protein Amet_2410 1 None None None 150388049 Common - 3-beta hydroxysteroid dehydrogenase/isomerase Amet_0204 101 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150391291 Nonpathogen - hypothetical protein Amet_3559 1 None None None 150389249 Common - Methyltransferase type 11 Amet_1440 103 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150389311 Common - integral membrane sensor signal transduction histidine kinase Amet_1507 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390790 Common - transposase, IS4 family protein Amet_3040 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150388170 Common - modification methylase, HemK family Amet_0330 230 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 150388569 Common - hypothetical protein Amet_0734 4 None None None 150392134 Common rpsM 30S ribosomal protein S13 Amet_4452 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 150388160 Common - alpha/beta hydrolase fold Amet_0320 167 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150389301 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Amet_1497 186 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150391530 Nonpathogen - transposase and inactivated derivatives-like protein Amet_3801 6 None None None 150390213 Nonpathogen - hypothetical protein Amet_2449 3 None None None 150388720 Common - helix-turn-helix- domain containing protein, AraC type Amet_0888 128 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150389597 Nonpathogen - hypothetical protein Amet_1817 1 None None None 150390307 Common - DNA mismatch repair protein MutS Amet_2544 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150391149 Common - citrate lyase subunit gamma Amet_3411 26 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 150389023 Common - MgtC/SapB transporter Amet_1205 118 COG1285 SapB, Uncharacterized membrane protein Function unknown 150389371 Nonpathogen - hypothetical protein Amet_1582 3 None None None 150391858 Common - SMC domain protein Amet_4167 142 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150392179 Common - RNA methyltransferase, TrmH family, group 3 Amet_4497 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150390167 Nonpathogen - hypothetical protein Amet_2403 1 None None None 150388895 Common - GTP-binding protein, HSR1-related Amet_1073 198 COG0218 COG0218, Predicted GTPase General function prediction only 150390595 Nonpathogen - hypothetical protein Amet_2835 1 None None None 150388226 Common - Transposase-like, Mu-like protein Amet_0388 35 None None None 150390858 Common - Carboxymuconolactone decarboxylase Amet_3108 11 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 150391092 Nonpathogen - hypothetical protein Amet_3354 1 None None None 150391973 Nonpathogen - hypothetical protein Amet_4287 1 None None None 150392060 Common - 3D domain protein Amet_4376 14 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150391115 Common - SCP-like extracellular protein Amet_3377 59 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150388340 Common - fumarylacetoacetate (FAA) hydrolase Amet_0503 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 150388974 Common - phosphonate metabolism protein Amet_1153 30 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 150390137 Common - alanine racemase domain protein Amet_2373 19 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 150389264 Common - GCN5-related N-acetyltransferase Amet_1455 82 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150391737 Common - hypothetical protein Amet_4045 3 None None None 150390193 Common - hypothetical protein Amet_2429 2 None None None 150390414 Common - adenylosuccinate lyase Amet_2652 203 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 150392299 Nonpathogen - hypothetical protein Amet_4618 1 None None None 150388432 Common - prevent-host-death family protein Amet_0595 8 None None None 150390652 Common - peptidase M16 domain protein Amet_2892 59 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150389783 Common - Methyltransferase type 11 Amet_2010 177 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150389165 Common - glycine cleavage system H protein Amet_1355 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 150388258 Common - hypothetical protein Amet_0420 11 COG4834 COG4834, Uncharacterized protein conserved in bacteria Function unknown 150391637 Common - ABC-2 type transporter Amet_3936 121 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150389725 Common - phage uncharacterized protein Amet_1952 23 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 150392303 Common - phosphate ABC transporter, inner membrane subunit PstA Amet_4622 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 150390415 Common - aminotransferase, class I and II Amet_2653 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150391222 Common - Radical SAM domain protein Amet_3484 100 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150387906 Common - conserved hypothetical protein 698 Amet_0053 114 COG2855 COG2855, Predicted membrane protein Function unknown 150388389 Common - TRAP dicarboxylate transporter, DctM subunit Amet_0552 127 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150391759 Common - putative PAS/PAC sensor protein Amet_4067 35 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150390904 Common - putative transcriptional regulator, GntR family Amet_3155 224 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150389473 Nonpathogen - hypothetical protein Amet_1686 7 None None None 150389788 Common - carbon-monoxide dehydrogenase, catalytic subunit Amet_2016 44 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150388815 Common - Radical SAM domain protein Amet_0988 92 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150392031 Nonpathogen - hypothetical protein Amet_4347 1 None None None 150391859 Common - nuclease SbcCD, D subunit Amet_4168 120 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 150392373 Common - ATP-dependent DNA helicase RecQ Amet_4695 235 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 150388321 Common - succinyl-CoA synthetase, beta subunit Amet_0484 207 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 150388950 Common - putative sulfonate/nitrate transport system substrate-binding protein Amet_1129 56 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150388502 Common - D-proline reductase (dithiol) Amet_0667 11 None None None 150391569 Common - iron-containing alcohol dehydrogenase Amet_3842 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150390256 Common - Sporulation stage III, protein AB Amet_2493 14 None None None 150388308 Common - (2Fe-2S)-binding domain protein Amet_0471 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 150392259 Common - microcompartments protein Amet_4578 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150388459 Common - transposase, IS4 Amet_0623 14 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150391802 Common - sigma54 specific transcriptional regulator, Fis family Amet_4111 166 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150390365 Common - hypothetical protein Amet_2603 58 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 150391286 Common - ABC transporter related Amet_3552 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150388711 Common - hypothetical protein Amet_0879 16 None None None 150391583 Common - transcriptional regulator, TetR family Amet_3860 37 COG1309 AcrR, Transcriptional regulator Transcription 150392464 Common - hypothetical protein Amet_4788 13 None None None 150390959 Common - 2-hydroxyglutaryl-CoA dehydratase, D-component Amet_3211 38 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 150388684 Common - restriction modification system DNA specificity domain Amet_0849 98 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 150390374 Nonpathogen - transcriptional regulator, XRE family Amet_2612 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 150388074 Common - dihydrodipicolinate synthase Amet_0229 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150391891 Common - aspartate carbamoyltransferase regulatory subunit Amet_4201 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 150387987 Common - dimethyladenosine transferase Amet_0138 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 150389440 Common - ABC transporter related Amet_1653 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150391840 Nonpathogen - hypothetical protein Amet_4149 4 None None None 150391691 Common - regulatory protein, ArsR Amet_3999 152 COG0640 ArsR, Predicted transcriptional regulators Transcription 150389697 Nonpathogen - hypothetical protein Amet_1923 1 None None None 150392314 Common - protein of unknown function DUF421 Amet_4633 57 COG2323 COG2323, Predicted membrane protein Function unknown 150390671 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2911 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 150389281 Nonpathogen - hypothetical protein Amet_1473 1 None None None 150392374 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_4696 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150390789 Common - Endonuclease/exonuclease/phosphatase Amet_3039 86 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 150390233 Common - protein of unknown function DUF340, membrane Amet_2469 49 COG2431 COG2431, Predicted membrane protein Function unknown 150388219 Nonpathogen - hypothetical protein Amet_0380 1 None None None 150388122 Nonpathogen - hypothetical protein Amet_0280 1 None None None 150388556 Nonpathogen - hypothetical protein Amet_0721 5 None None None 150391345 Common - ferric uptake regulator, Fur family Amet_3613 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150390576 Common - response regulator receiver protein Amet_2816 227 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150389495 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Amet_1709 161 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150390085 Common - L-serine dehydratase, iron-sulfur-dependent, alpha subunit Amet_2318 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 150390497 Common - DNA protecting protein DprA Amet_2736 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 150391036 Common - hypothetical protein Amet_3295 35 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 150388232 Nonpathogen - hypothetical protein Amet_0394 1 None None None 150388523 Common - hypothetical protein Amet_0688 6 None None None 150391020 Nonpathogen - hypothetical protein Amet_3273 1 None None None 150389205 Common - putative transcriptional regulator, MerR family Amet_1395 13 COG0789 SoxR, Predicted transcriptional regulators Transcription 150391591 Common - integral membrane sensor signal transduction histidine kinase Amet_3868 188 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150392047 Common - hypothetical protein Amet_4363 14 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 150390241 Nonpathogen - hypothetical protein Amet_2477 1 None None None 150392406 Common - protein of unknown function DUF6, transmembrane Amet_4728 128 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150388744 Common - Ion transport 2 domain protein Amet_0913 115 None None None 150388153 Common - efflux transporter, RND family, MFP subunit Amet_0312 176 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150388762 Common - ABC transporter related Amet_0932 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 150389136 Common - ABC transporter related Amet_1324 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150391649 Common - AAA - ATPase, putative Amet_3948 26 None None None 150388140 Common - S-layer domain protein Amet_0298 22 None None None 150391183 Common - hexapeptide transferase family protein Amet_3445 145 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 150390112 Common - protein-export membrane protein SecD Amet_2348 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 150391847 Common - putative multicomponent Na+:H+ antiporter subunit B Amet_4156 27 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 150391750 Common - N-6 DNA methylase Amet_4058 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150388194 Common - ATP synthase F1, epsilon subunit Amet_0354 76 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 150391761 Common - 6-phosphofructokinase Amet_4069 155 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 150390890 Common - two component transcriptional regulator, LuxR family Amet_3141 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150388729 Common - binding-protein-dependent transport systems inner membrane component Amet_0897 160 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150388003 Common - UDP-N-acetylglucosamine pyrophosphorylase Amet_0156 236 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 150388241 Nonpathogen - hypothetical protein Amet_0403 1 None None None 150388957 Common - MATE efflux family protein Amet_1136 156 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150390013 Nonpathogen - hypothetical protein Amet_2245 2 None None None 150390825 Common - GerA spore germination protein Amet_3075 15 None None None 150391459 Common - TRAP dicarboxylate transporter- DctP subunit Amet_3729 104 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150389962 Common - metal dependent phosphohydrolase Amet_2193 99 COG1203 COG1203, Predicted helicases General function prediction only 150391229 Common - hypothetical protein Amet_3491 140 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 150391543 Common - hypothetical protein Amet_3815 11 None None None 150390385 Common - Protein-glutamate O-methyltransferase Amet_2623 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 150390123 Common - aspartyl-tRNA synthetase Amet_2359 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150391157 Common - acetolactate synthase, small subunit Amet_3419 152 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 150391267 Common - TRAP dicarboxylate transporter, DctM subunit Amet_3531 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150389554 Common - flagellar protein FlaG protein Amet_1772 30 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 150389894 Nonpathogen - hypothetical protein Amet_2125 1 None None None 150389938 Nonpathogen - hypothetical protein Amet_2169 5 None None None 150390062 Common - septum site-determining protein MinD Amet_2295 152 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 150389775 Common - ABC transporter related Amet_2002 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150392285 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Amet_4604 185 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 150392340 Common - asparagine synthetase AsnA Amet_4660 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 150391652 Common - ABC transporter related Amet_3954 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150388845 Common - riboflavin biosynthesis protein RibD Amet_1018 230 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 150391554 Common - microcompartments protein Amet_3827 27 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150391485 Common mtnK methylthioribose kinase Amet_3756 27 COG4857 COG4857, Predicted kinase General function prediction only 150391174 Common - glycosyl transferase, family 2 Amet_3436 105 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150391511 Common - Cupin 2, conserved barrel domain protein Amet_3782 38 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150388108 Common - Ethanolamine utilization protein EutN/carboxysome structural protein Ccml Amet_0265 43 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150389036 Common - Domain of unknown function DUF1893 Amet_1218 5 None None None 150391746 Common - hypothetical protein Amet_4054 4 None None None 150390799 Common - GrpE protein Amet_3049 233 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 150392409 Nonpathogen - hypothetical protein Amet_4731 1 None None None 150388704 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Amet_0869 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 150390695 Common - peptidase S41 Amet_2935 137 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150392426 Nonpathogen - hypothetical protein Amet_4750 2 None None None 150390971 Common - citrate lyase, alpha subunit Amet_3223 28 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 150391736 Common - hypothetical protein Amet_4044 4 None None None 150391872 Common - N-acetylglucosamine-6-phosphate deacetylase Amet_4181 121 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 150390391 Common - HI0933 family protein Amet_2629 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 150390549 Common - DNA-directed RNA polymerase, omega subunit Amet_2789 19 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 150389144 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1332 14 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 150392347 Common - 2-nitropropane dioxygenase, NPD Amet_4667 135 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 150390935 Common - FMN-binding domain protein Amet_3187 57 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 150388103 Common - microcompartments protein Amet_0260 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150389009 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal protein Amet_1191 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 150390074 Common - GTP-binding protein Obg/CgtA Amet_2307 249 COG0536 Obg, Predicted GTPase General function prediction only 150391270 Common - dihydroxy-acid dehydratase Amet_3534 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150390294 Common - chromosome segregation and condensation protein ScpA Amet_2531 150 COG1354 COG1354, Uncharacterized conserved protein Function unknown 150388300 Common - alpha/beta hydrolase fold Amet_0462 87 COG2267 PldB, Lysophospholipase Lipid metabolism 150389794 Common - methylenetetrahydrofolate reductase Amet_2022 65 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 150391695 Nonpathogen - hypothetical protein Amet_4003 2 None None None 150390500 Common - protein of unknown function UPF0102 Amet_2739 157 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 150392100 Nonpathogen - hypothetical protein Amet_4418 2 None None None 150389215 Common - phage integrase family protein Amet_1405 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150389670 Common - hypothetical protein Amet_1895 15 None None None 150388935 Common - hypothetical protein Amet_1114 7 None None None 150390780 Common - diacylglycerol kinase Amet_3030 101 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 150391316 Common - inner-membrane translocator Amet_3584 130 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 150389072 Common - metal dependent phosphohydrolase Amet_1256 129 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150387965 Common - protein of unknown function DUF1568 Amet_0114 52 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150392244 Common - biotin/lipoyl attachment Amet_4563 24 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 150388129 Common - heat shock protein DnaJ domain protein Amet_0287 52 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150391307 Nonpathogen - preprotein translocase, SecG subunit Amet_3575 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 150392194 Common - ATPase AAA-2 domain protein Amet_4512 228 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150389539 Common - IstB domain protein ATP-binding protein Amet_1757 92 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150391230 Common - sulfate adenylyltransferase, large subunit Amet_3492 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 150391881 Common - transcriptional regulator, RpiR family Amet_4190 88 COG1737 RpiR, Transcriptional regulators Transcription 150388352 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Amet_0515 100 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 150388583 Common - protein of unknown function DUF1568 Amet_0748 50 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389231 Common - ThiJ/PfpI domain protein Amet_1421 26 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 150391043 Common - hypothetical protein Amet_3302 8 None None None 150389625 Common - hypothetical protein Amet_1845 39 COG1725 COG1725, Predicted transcriptional regulators Transcription 150390978 Common - transcriptional regulator, DeoR family Amet_3230 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 150391614 Common - ABC-type spermidine/putrescine transport systems ATPase components-like protein Amet_3908 245 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 150391936 Common - sigma54 specific transcriptional regulator, Fis family Amet_4248 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150390300 Common - Aluminium resistance family protein Amet_2537 29 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 150388668 Common groES co-chaperonin GroES Amet_0833 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 150390069 Common - ribonuclease, Rne/Rng family Amet_2302 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 150390288 Common - inosine guanosine and xanthosine phosphorylase family Amet_2525 135 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 150388785 Common - hypothetical protein Amet_0955 13 COG5401 COG5401, Spore germination protein General function prediction only 150389250 Common - HEAT domain containing protein Amet_1441 37 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 150391685 Common - ParB domain protein nuclease Amet_3993 147 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150390558 Common - transcriptional regulator, TraR/DksA family Amet_2798 96 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 150388964 Common - multiple resistance and pH regulation protein F Amet_1143 27 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 150392109 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Amet_4427 76 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 150390324 Common - hypothetical protein Amet_2562 2 None None None 150392397 Common - ABC transporter related Amet_4719 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388212 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Amet_0372 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 150390906 Common - Aldehyde ferredoxin oxidoreductase Amet_3157 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 150388205 Common - cell shape determining protein, MreB/Mrl family Amet_0365 215 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 150389564 Common - metallophosphoesterase Amet_1782 89 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150392125 Common rplM 50S ribosomal protein L13 Amet_4443 233 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 150391374 Common - glutaminase Amet_3642 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 150388927 Common - hypothetical protein Amet_1106 6 None None None 150389422 Common - ribosomal protein L20 Amet_1635 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 150389813 Common - NmrA family protein Amet_2041 81 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150390738 Common - multi-sensor signal transduction histidine kinase Amet_2979 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150391595 Nonpathogen - hypothetical protein Amet_3883 1 None None None 150391071 Common - Indolepyruvate ferredoxin oxidoreductase Amet_3333 108 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 150392018 Common - protein of unknown function DUF421 Amet_4334 71 COG2323 COG2323, Predicted membrane protein Function unknown 150392079 Nonpathogen - hypothetical protein Amet_4396 1 None None None 150388158 Common - protein of unknown function DUF849 Amet_0318 63 COG3246 COG3246, Uncharacterized conserved protein Function unknown 150391354 Common - ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Amet_3622 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 150388115 Nonpathogen - hypothetical protein Amet_0272 2 None None None 150391601 Common - lipoprotein, YaeC family Amet_3892 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 150390862 Common - ErfK/YbiS/YcfS/YnhG family protein Amet_3113 42 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150388611 Common - VanZ family protein Amet_0776 11 COG5652 COG5652, Predicted integral membrane protein Function unknown 150388871 Common - Integrase, catalytic region Amet_1046 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389602 Nonpathogen - hypothetical protein Amet_1822 1 None None None 150390581 Common - S-adenosylmethionine decarboxylase Amet_2821 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 150388656 Common - FAD linked oxidase domain protein Amet_0821 203 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150391611 Common - daunorubicin resistance ABC transporter ATPase subunit Amet_3905 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150392011 Common - A/G-specific adenine glycosylase Amet_4327 239 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 150389997 Common - protein of unknown function UPF0029 Amet_2229 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 150392451 Common - hypothetical protein Amet_4775 5 None None None 150390946 Common - aspartate-semialdehyde dehydrogenase Amet_3198 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 150390093 Common - histidine kinase Amet_2326 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390942 Common - aspartate kinase Amet_3194 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 150391562 Common - glycyl-radical enzyme activating protein family Amet_3835 65 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150388570 Nonpathogen - hypothetical protein Amet_0735 1 None None None 150391493 Common - carbon-monoxide dehydrogenase, catalytic subunit Amet_3764 39 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150392324 Common - Aldehyde ferredoxin oxidoreductase Amet_4643 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 150389381 Common - small acid-soluble spore protein, alpha/beta type Amet_1592 15 None None None 150391067 Common - binding-protein-dependent transport systems inner membrane component Amet_3329 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391943 Common - uracil-DNA glycosylase Amet_4255 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 150389843 Nonpathogen - hypothetical protein Amet_2073 1 None None None 150390631 Common - sporulation sigma factor SigE Amet_2871 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150391776 Nonpathogen - hypothetical protein Amet_4084 2 None None None 150389418 Common thrS threonyl-tRNA synthetase Amet_1631 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150389824 Nonpathogen - Histidyl-tRNA synthetase-like protein Amet_2053 5 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150389258 Common - methyl-accepting chemotaxis sensory transducer Amet_1449 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150392388 Common - SirA family protein Amet_4710 16 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 150388417 Common - sodium:neurotransmitter symporter Amet_0580 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 150389619 Common - Fe-S cluster domain protein Amet_1839 18 COG4871 COG4871, Uncharacterized protein conserved in archaea Function unknown 150390871 Common - extracellular solute-binding protein, family 5 Amet_3122 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150388182 Common - sodium:neurotransmitter symporter Amet_0342 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 150390049 Common - electron transport complex, RnfABCDGE type, G subunit Amet_2282 61 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 150390965 Common - biotin/lipoyl attachment domain-containing protein Amet_3217 196 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 150388514 Common - putative oxidoreductase Amet_0679 203 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150389191 Nonpathogen - hypothetical protein Amet_1381 4 COG0011 COG0011, Uncharacterized conserved protein Function unknown 150390562 Common - protein of unknown function YGGT Amet_2802 38 None None None 150390206 Nonpathogen - hypothetical protein Amet_2442 1 None None None 150389288 Common - ABC-2 type transporter Amet_1482 9 None None None 150387862 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Amet_0009 40 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 150389763 Nonpathogen - hypothetical protein Amet_1990 1 None None None 150388562 Common - flagellar hook-associated protein FlgK Amet_0727 121 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 150389171 Common - hypothetical protein Amet_1361 8 None None None 150389208 Common - NMT1/THI5 like protein Amet_1398 77 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150389084 Common - Dihydroxy-acid dehydratase Amet_1268 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150389875 Nonpathogen - hypothetical protein Amet_2105 1 None None None 150388297 Common - Xylose isomerase domain protein TIM barrel Amet_0459 61 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 150388854 Nonpathogen - hypothetical protein Amet_1027 1 None None None 150390756 Common - integral membrane sensor signal transduction histidine kinase Amet_3002 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391256 Common - nitrogenase MoFe cofactor biosynthesis protein NifE Amet_3519 60 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150388637 Common - hypothetical protein Amet_0802 22 COG3601 COG3601, Predicted membrane protein Function unknown 150388024 Common - carboxyl-terminal protease Amet_0177 186 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150389923 Nonpathogen - hypothetical protein Amet_2154 1 None None None 150391428 Common - diguanylate cyclase Amet_3698 189 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 150391133 Common - transposase IS200-family protein Amet_3395 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150390431 Common - riboflavin biosynthesis protein RibF Amet_2669 211 COG0196 RibF, FAD synthase Coenzyme metabolism 150388730 Common - binding-protein-dependent transport systems inner membrane component Amet_0898 169 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150390542 Common - sun protein Amet_2782 216 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 150391768 Common - deoxynucleoside kinase Amet_4076 41 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 150392211 Common - membrane protein Amet_4529 11 COG4684 COG4684, Predicted membrane protein Function unknown 150390969 Common - methyl-accepting chemotaxis sensory transducer Amet_3221 167 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150388598 Common - helix-turn-helix- domain containing protein, AraC type Amet_0763 107 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150391423 Common - hypothetical protein Amet_3693 14 COG4720 COG4720, Predicted membrane protein Function unknown 150391525 Common - xylose isomerase Amet_3796 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 150388004 Common - ribose-phosphate pyrophosphokinase Amet_0157 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 150392470 Common - parB-like partition protein Amet_4794 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150390354 Nonpathogen - hypothetical protein Amet_2592 1 None None None 150391797 Common - hypothetical protein Amet_4106 13 None None None 150387956 Common - two component transcriptional regulator, LytTR family Amet_0103 164 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150392335 Common - phospholipase D/Transphosphatidylase Amet_4655 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 150391231 Common - sulfate adenylyltransferase subunit 2 Amet_3493 150 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 150389733 Common - hypothetical protein Amet_1960 5 None None None 150392238 Nonpathogen - hypothetical protein Amet_4556 1 None None None 150389612 Nonpathogen - hypothetical protein Amet_1832 1 None None None 150388588 Common - transcriptional regulator, XRE family Amet_0753 14 COG1476 COG1476, Predicted transcriptional regulators Transcription 150389014 Common - protein of unknown function DUF6, transmembrane Amet_1196 103 COG2962 RarD, Predicted permeases General function prediction only 150392019 Common - NADH:flavin oxidoreductase/NADH oxidase Amet_4335 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150390912 Common - hypothetical protein Amet_3163 6 None None None 150389216 Common - hypothetical protein Amet_1406 3 None None None 150389266 Common - two component transcriptional regulator, winged helix family Amet_1457 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150388294 Common - ABC-type sugar transport system periplasmic component-like protein Amet_0456 84 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150389012 Common - creatinase Amet_1194 153 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150389784 Common - cysteine desulfurase family protein Amet_2011 242 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150390253 Common - translation elongation factor P Amet_2490 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 150391490 Common - hypothetical protein Amet_3761 3 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 150392332 Common - putative proton-coupled thiamine transporter YuaJ Amet_4652 12 COG3859 COG3859, Predicted membrane protein Function unknown 150391730 Common - virulence-related protein Amet_4038 13 None None None 150388117 Nonpathogen - hypothetical protein Amet_0274 1 None None None 150388110 Common - microcompartments protein Amet_0267 32 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150389267 Common - integral membrane sensor signal transduction histidine kinase Amet_1458 205 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150389994 Common - PBS lyase HEAT domain protein repeat-containing protein Amet_2226 7 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 150388247 Common - hypothetical protein Amet_0409 3 COG5566 COG5566, Uncharacterized conserved protein Function unknown 150388846 Common - riboflavin synthase subunit alpha Amet_1019 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 150392279 Common - spore germination protein Amet_4598 23 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 150389019 Common - small acid-soluble spore protein, alpha/beta type Amet_1201 2 None None None 150388806 Common - transcriptional regulator, LysR family Amet_0979 192 COG0583 LysR, Transcriptional regulator Transcription 150390228 Nonpathogen - hypothetical protein Amet_2464 1 None None None 150390693 Common - NUDIX hydrolase Amet_2933 167 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150390643 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Amet_2883 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 150388063 Common - hypothetical protein Amet_0218 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 150390339 Common - hypothetical protein Amet_2577 6 None None None 150390465 Common - flagellar biosynthesis protein FlhA Amet_2703 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 150392205 Common - 3-hydroxybutyryl-CoA dehydrogenase Amet_4523 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 150390284 Common - NUDIX hydrolase Amet_2521 190 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 150391069 Common - extracellular solute-binding protein, family 5 Amet_3331 180 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150388736 Common - Coat F domain protein Amet_0905 11 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 150390878 Nonpathogen - hypothetical protein Amet_3129 1 None None None 150389937 Nonpathogen - hypothetical protein Amet_2168 1 None None None 150388005 Common - peptidyl-tRNA hydrolase Amet_0158 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 150389677 Common - ABC transporter related Amet_1903 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150390299 Common - transposase Amet_2536 6 None None None 150391219 Common - twitching motility protein Amet_3481 183 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 150389878 Common - putative transcriptional regulator, XRE family Amet_2109 49 COG3655 COG3655, Predicted transcriptional regulator Transcription 150389517 Common - hypothetical protein Amet_1731 12 COG5418 COG5418, Predicted secreted protein Function unknown 150391600 Common - hypothetical protein Amet_3891 24 COG3875 COG3875, Uncharacterized conserved protein Function unknown 150391798 Common - hydrogenase, Fe-only Amet_4107 184 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150388557 Common - helicase, RecD/TraA family Amet_0722 145 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 150388906 Common - Rubredoxin-type Fe(Cys)4 protein Amet_1084 120 COG1773 COG1773, Rubredoxin Energy production and conversion 150389383 Common - phage integrase family protein Amet_1594 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150388926 Common - Uncharacterized protein UPF0065 Amet_1105 64 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 150391852 Nonpathogen - hypothetical protein Amet_4161 1 None None None 150388746 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Amet_0916 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 150388141 Common - TPR repeat-containing protein Amet_0299 47 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150389566 Nonpathogen - hypothetical protein Amet_1784 2 None None None 150391132 Common - transposase, IS605 OrfB family Amet_3394 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389194 Common - FMN-binding domain protein Amet_1384 11 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 150388285 Nonpathogen - hypothetical protein Amet_0447 1 None None None 150389283 Nonpathogen - hypothetical protein Amet_1476 1 None None None 150390006 Nonpathogen - hypothetical protein Amet_2238 4 None None None 150390044 Common - HPr kinase Amet_2277 8 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 150390852 Common - metal dependent phosphohydrolase Amet_3102 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 150390705 Common - glycogen/starch/alpha-glucan phosphorylase Amet_2945 145 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 150391726 Nonpathogen - hypothetical protein Amet_4034 1 None None None 150390894 Common - protein of unknown function DUF896 Amet_3145 12 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 150392103 Common - Linocin_M18 bacteriocin protein Amet_4421 19 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 150388996 Nonpathogen - protein of unknown function DUF1622 Amet_1178 5 COG4828 COG4828, Predicted membrane protein Function unknown 150391524 Common - ROK family protein Amet_3795 153 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150391898 Common - dihydroorotate dehydrogenase family protein Amet_4208 235 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 150388018 Nonpathogen - Septum formation initiator Amet_0171 2 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 150387871 Common - L-aspartate oxidase Amet_0018 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 150389061 Nonpathogen - hypothetical protein Amet_1244 1 None None None 150389721 Nonpathogen - hypothetical protein Amet_1948 1 None None None 150390065 Common - peptidase M23B Amet_2298 11 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150392077 Common - Uncharacterized ATPase putative transposase Amet_4393 15 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 150391534 Common - MATE efflux family protein Amet_3806 123 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150388715 Nonpathogen - hypothetical protein Amet_0883 1 None None None 150391047 Common - integral membrane sensor signal transduction histidine kinase Amet_3308 223 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150392043 Common - hypothetical protein Amet_4359 3 None None None 150392391 Common - hypothetical protein Amet_4713 5 COG1478 COG1478, Uncharacterized conserved protein Function unknown 150391739 Nonpathogen - HNH endonuclease Amet_4047 2 None None None 150388299 Common - hypothetical protein Amet_0461 2 None None None 150388732 Common - 5-keto-4-deoxyuronate isomerase Amet_0900 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 150388787 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Amet_0957 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 150389261 Common - GCN5-related N-acetyltransferase Amet_1452 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150390714 Common - D-alanine--D-alanine ligase Amet_2954 220 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150387891 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Amet_0038 172 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 150388067 Common - putative transcriptional regulator Amet_0222 61 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 150388530 Nonpathogen - hypothetical protein Amet_0695 5 None None None 150389315 Common - Cyclopropane-fatty-acyl-phospholipid synthase Amet_1511 39 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 150392261 Common - microcompartments protein Amet_4580 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150391877 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Amet_4186 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150392343 Common - FAD dependent oxidoreductase Amet_4663 113 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 150390834 Common - Uncharacterized protein UPF0065 Amet_3084 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 150387893 Common - C4-dicarboxylate anaerobic carrier Amet_0040 59 COG1288 COG1288, Predicted membrane protein Function unknown 150388039 Common - lipopolysaccharide biosynthesis protein Amet_0192 66 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 150388644 Nonpathogen - hypothetical protein Amet_0809 1 None None None 150391040 Common - Rhodanese domain protein Amet_3299 4 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150389494 Common - alanine racemase domain protein Amet_1708 61 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 150389071 Common - response regulator receiver protein Amet_1255 109 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150392243 Common - aspartate aminotransferase Amet_4562 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150391839 Nonpathogen - hypothetical protein Amet_4148 2 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 150389411 Common - conserved hypothetical protein; putative phospholipase D endonuclease domain Amet_1624 4 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 150389851 Nonpathogen - hypothetical protein Amet_2081 1 None None None 150390997 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Amet_3249 197 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150390151 Nonpathogen - hypothetical protein Amet_2387 3 None None None 150390932 Common - nitrogen regulatory protein P-II Amet_3184 19 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150391810 Common - Extracellular ligand-binding receptor Amet_4119 146 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 150388798 Common - TRAP dicarboxylate transporter, DctM subunit Amet_0971 132 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150391612 Nonpathogen - hypothetical protein Amet_3906 1 None None None 150390656 Common - GTP-binding protein YchF Amet_2896 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 150390208 Nonpathogen - hypothetical protein Amet_2444 1 None None None 150391994 Common - butyrate kinase Amet_4310 103 COG3426 COG3426, Butyrate kinase Energy production and conversion 150387885 Common - ribosomal protein S6 Amet_0032 205 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 150388965 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Amet_1144 44 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 150389033 Common - branched-chain amino acid transport Amet_1215 14 COG4392 COG4392, Predicted membrane protein Function unknown 150390559 Common - Adenosylhomocysteine nucleosidase Amet_2799 95 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 150390941 Common - aminotransferase class-III Amet_3193 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150391795 Common - Radical SAM domain protein Amet_4104 114 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 150388156 Common - response regulator receiver protein Amet_0316 215 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150388618 Common - aminotransferase, class IV Amet_0783 168 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150389079 Common - GntR domain protein Amet_1263 141 COG2186 FadR, Transcriptional regulators Transcription 150391587 Nonpathogen - hypothetical protein Amet_3864 1 None None None 150391264 Nonpathogen - hypothetical protein Amet_3528 1 None None None 150388305 Common - methyl-accepting chemotaxis sensory transducer Amet_0467 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150389090 Common - metal dependent phosphohydrolase Amet_1274 125 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 150390124 Common - hypothetical protein Amet_2360 17 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 150390493 Common - putative CheW protein Amet_2732 187 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150391070 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Amet_3332 80 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 150392181 Nonpathogen - hypothetical protein Amet_4499 1 None None None 150388405 Common - homoserine kinase Amet_0568 123 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 150388526 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Amet_0691 207 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150390565 Nonpathogen - hypothetical protein Amet_2805 3 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150391806 Common - ABC transporter related Amet_4115 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150390859 Common - Endoribonuclease L-PSP Amet_3109 125 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 150391634 Common - zinc/iron permease Amet_3932 98 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 150388890 Common clpX ATP-dependent protease ATP-binding subunit Amet_1068 226 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 150391778 Common - two component transcriptional regulator, LytTR family Amet_4087 148 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150392124 Common - ribosomal protein S9 Amet_4442 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 150391393 Common - extracellular solute-binding protein, family 3 Amet_3661 183 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150391367 Common - ATP-dependent protease Amet_3635 132 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 150388650 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal protein Amet_0815 178 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 150389895 Nonpathogen - hypothetical protein Amet_2126 1 None None None 150390614 Common - Sporulation stage IV, protein A Amet_2854 15 None None None 150390292 Common - Polynucleotide adenylyltransferase region Amet_2529 240 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 150389048 Common - permease Amet_1230 94 COG0701 COG0701, Predicted permeases General function prediction only 150389845 Common - inner-membrane translocator Amet_2075 163 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 150391453 Common - beta-lactamase domain protein Amet_3723 89 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150388516 Common - molybdopterin dehydrogenase, FAD-binding Amet_0681 101 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 150391196 Common - 2-isopropylmalate synthase Amet_3458 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150388011 Common - MazG family protein Amet_0164 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 150387904 Common - Radical SAM domain protein Amet_0051 178 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150390438 Common - NusA antitermination factor Amet_2676 230 COG0195 NusA, Transcription elongation factor Transcription 150389362 Common - diguanylate cyclase Amet_1573 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150390622 Common - hypothetical protein Amet_2862 9 None None None 150391258 Common - nitrogenase molybdenum-iron protein alpha chain Amet_3521 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150388195 Common - hypothetical protein Amet_0355 6 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 150391403 Nonpathogen - hypothetical protein Amet_3673 2 None None None 150388165 Common - Thymidine kinase Amet_0325 94 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 150390725 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Amet_2965 202 COG0281 SfcA, Malic enzyme Energy production and conversion 150391083 Common - molybdopterin dehydrogenase, FAD-binding Amet_3345 54 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 150392083 Common - plasmid maintenance system antidote protein, XRE family Amet_4400 4 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 150389471 Common - uracil-xanthine permease Amet_1684 136 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150391436 Common - Cystathionine gamma-synthase Amet_3706 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150391689 Common - heavy metal translocating P-type ATPase Amet_3997 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150391643 Common - ABC transporter related Amet_3942 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150389595 Nonpathogen - hypothetical protein Amet_1815 1 None None None 150390692 Common - ABC-type phosphate transport system periplasmic component-like protein Amet_2932 109 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 150391510 Common - major facilitator superfamily MFS_1 Amet_3781 96 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 150391535 Common - ABC transporter related Amet_3807 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150392377 Common - DEAD/DEAH box helicase domain protein Amet_4699 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150387984 Common - SCP-like extracellular protein Amet_0135 57 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150390134 Common - hypothetical protein Amet_2370 7 None None None 150388564 Nonpathogen - hypothetical protein Amet_0729 7 None None None 150388472 Common - protein of unknown function DUF881 Amet_0637 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 150390315 Common - hypothetical protein Amet_2553 5 COG1262 COG1262, Uncharacterized conserved protein Function unknown 150388723 Common - Cof-like hydrolase Amet_0891 130 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150388741 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Amet_0910 241 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 150391714 Common - phage major tail protein, phi13 family Amet_4022 8 None None None 150391180 Common - NAD-dependent epimerase/dehydratase Amet_3442 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150391311 Common - Phosphoglycerate kinase Amet_3579 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 150388837 Common - sulphate transporter Amet_1010 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 150391290 Common - two component transcriptional regulator, winged helix family Amet_3556 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150388939 Common - binding-protein-dependent transport systems inner membrane component Amet_1118 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389055 Nonpathogen - putative mercuric transport protein, selenocysteine-containing Amet_1238 1 None None None 150391332 Common - uncharacterized conserved protein, repeat-containing protein Amet_3600 15 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 150391670 Common - SMC domain protein Amet_3975 83 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150392255 Common - adenine deaminase Amet_4574 78 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 150390054 Nonpathogen - hypothetical protein Amet_2287 1 None None None 150390744 Common - protein of unknown function DUF34 Amet_2990 113 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 150388043 Nonpathogen - hypothetical protein Amet_0198 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150391970 Nonpathogen - hypothetical protein Amet_4283 1 None None None 150388603 Common - hypothetical protein Amet_0768 17 None None None 150391144 Common - glycosyl transferase, family 2 Amet_3406 58 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150391945 Common - protein of unknown function DUF45 Amet_4257 152 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 150390991 Nonpathogen - hypothetical protein Amet_3243 1 None None None 150388073 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Amet_0228 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 150391348 Common - cobyric acid synthase CobQ Amet_3616 154 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 150390420 Common - recA protein Amet_2658 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 150388206 Common - ABC transporter related Amet_0366 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390923 Common - NAD(+) kinase Amet_3174 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 150388686 Common - hypothetical protein Amet_0851 10 None None None 150392095 Nonpathogen - hypothetical protein Amet_4412 1 None None None 150388632 Common - sulfatase Amet_0797 70 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 150390271 Common - deoxyxylulose-5-phosphate synthase Amet_2508 225 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 150389213 Common - FolC bifunctional protein Amet_1403 218 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 150391496 Common - oligoendopeptidase F Amet_3767 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 150392033 Common - hypothetical protein Amet_4349 2 None None None 150390579 Common - Tetratricopeptide TPR_2 repeat protein Amet_2819 149 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 150387986 Common - primase/topoisomerase like protein Amet_0137 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 150388867 Nonpathogen - hypothetical protein Amet_1041 1 None None None 150389569 Common - hypothetical protein Amet_1788 3 None None None 150390059 Common - hypothetical protein Amet_2292 14 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 150391377 Common - glutamate 5-kinase Amet_3645 200 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 150390230 Common - ferric uptake regulator, Fur family Amet_2466 206 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150387912 Common - siroheme synthase Amet_0059 154 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 150388372 Nonpathogen - hypothetical protein Amet_0535 2 None None None 150389810 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2038 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388093 Common - microcompartments protein Amet_0250 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 150388325 Common - integral membrane sensor signal transduction histidine kinase Amet_0488 141 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150388362 Common - cobalt ABC transporter, ATPase subunit Amet_0525 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150390570 Common - Substrate-binding region of ABC-type glycine betaine transport system Amet_2810 70 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 150391953 Common - zinc/iron permease Amet_4265 128 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 150388550 Common - putative small multi-drug export Amet_0715 18 COG2426 COG2426, Predicted membrane protein Function unknown 150391064 Common - xanthine phosphoribosyltransferase Amet_3326 57 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 150392407 Common - two component transcriptional regulator, winged helix family Amet_4729 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150388797 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Amet_0970 34 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 150391623 Common - palmitoyl-CoA hydrolase Amet_3918 9 None None None 150390115 Common - single-stranded-DNA-specific exonuclease RecJ Amet_2351 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 150389254 Common - Domain of unknown function DUF1858 Amet_1445 26 COG2461 COG2461, Uncharacterized conserved protein Function unknown 150389570 Common - hypothetical protein Amet_1789 3 None None None 150391464 Common - nitroreductase Amet_3735 9 COG0778 NfnB, Nitroreductase Energy production and conversion 150391189 Nonpathogen - hypothetical protein Amet_3451 2 None None None 150391226 Common - hypothetical protein Amet_3488 9 None None None 150389162 Common - CapA domain protein Amet_1352 65 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 150391368 Common - domain of unknown function DUF1730 Amet_3636 131 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150389747 Common - hypothetical protein Amet_1974 4 None None None 150390630 Common - sporulation sigma factor SigG Amet_2870 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150390823 Common - DEAD/DEAH box helicase domain protein Amet_3073 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150391110 Common - ABC transporter related Amet_3372 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150389306 Common - transcriptional regulator, TetR family Amet_1502 79 COG1309 AcrR, Transcriptional regulator Transcription 150390149 Nonpathogen - hypothetical protein Amet_2385 1 None None None 150388327 Nonpathogen - hypothetical protein Amet_0490 1 None None None 150388078 Common - ABC transporter related Amet_0234 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150389835 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2064 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388430 Common - nitroreductase Amet_0593 74 COG0778 NfnB, Nitroreductase Energy production and conversion 150391139 Common - dihydroxy-acid dehydratase Amet_3401 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150388913 Common - major facilitator superfamily MFS_1 Amet_1091 114 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150388593 Nonpathogen - hypothetical protein Amet_0758 2 None None None 150391920 Common - MATE efflux family protein Amet_4230 186 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150388758 Nonpathogen - hypothetical protein Amet_0928 1 None None None 150388893 Common - Sporulation protease LonB Amet_1071 240 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 150388951 Common - binding-protein-dependent transport systems inner membrane component Amet_1130 86 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150390036 Nonpathogen - hypothetical protein Amet_2268 4 None None None 150390081 Common - leucyl-tRNA synthetase Amet_2314 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150388608 Nonpathogen - hypothetical protein Amet_0773 1 None None None 150390639 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Amet_2879 213 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150391754 Common - aldo/keto reductase Amet_4062 192 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 150391284 Common - hypothetical protein Amet_3548 6 None None None 150390443 Common - putative membrane-associated zinc metalloprotease Amet_2681 212 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 150390484 Common - flagellar protein export ATPase FliI Amet_2722 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 150390328 Common - Phage XkdN-like protein Amet_2566 3 None None None 150391663 Common - protein of unknown function DUF262 Amet_3966 32 COG1479 COG1479, Uncharacterized conserved protein Function unknown 150390881 Nonpathogen - hypothetical protein Amet_3132 3 None None None 150389981 Common - anti-sigma F factor Amet_2213 24 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 150390170 Common - Peptidoglycan-binding domain 1 protein Amet_2406 9 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 150392048 Common - phage putative head morphogenesis protein, SPP1 gp7 family Amet_4364 17 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 150390903 Common - diacylglycerol kinase, catalytic region Amet_3154 119 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 150390349 Nonpathogen - hypothetical protein Amet_2587 1 None None None 150388816 Common - Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein Amet_0989 104 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 150390585 Common - Peptidoglycan-binding LysM Amet_2825 70 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 150389927 Common - para-aminobenzoate synthase, subunit I Amet_2158 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 150391176 Common - DegT/DnrJ/EryC1/StrS aminotransferase Amet_3438 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150391281 Common - histidinol phosphate phosphatase HisJ family Amet_3545 47 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 150392458 Nonpathogen - hypothetical protein Amet_4782 1 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 150391832 Nonpathogen - hypothetical protein Amet_4141 8 None None None 150390090 Common - selenocysteine synthase Amet_2323 75 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 150389376 Common - ABC transporter related Amet_1587 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150391764 Common - transcriptional activator domain Amet_4072 45 COG3899 COG3899, Predicted ATPase General function prediction only 150392270 Common - Formiminotransferase-cyclodeaminase Amet_4589 37 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 150392289 Common - ornithine carbamoyltransferase Amet_4608 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 150388022 Common - helix-turn-helix domain protein Amet_0175 5 None None None 150389406 Common - single-strand DNA-binding protein Amet_1619 4 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150390097 Common - ferric uptake regulator, Fur family Amet_2333 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150391391 Common - ABC transporter related Amet_3659 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150390550 Common - Guanylate kinase Amet_2790 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 150391509 Nonpathogen - hypothetical protein Amet_3780 1 None None None 150391610 Common - ABC-2 type transporter Amet_3904 42 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150389277 Common - HAD family hydrolase Amet_1468 17 COG4087 COG4087, Soluble P-type ATPase General function prediction only 150388081 Nonpathogen - hypothetical protein Amet_0238 1 None None None 150389324 Common - efflux transporter, RND family, MFP subunit Amet_1521 182 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150392222 Common - LAO/AO transport system ATPase Amet_4540 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 150391166 Common - hypothetical protein Amet_3428 6 None None None 150390405 Common - Serine-type D-Ala-D-Ala carboxypeptidase Amet_2643 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150392110 Common - thiamine pyrophosphate protein domain protein TPP-binding Amet_4428 110 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150390861 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Amet_3112 3 COG5015 COG5015, Uncharacterized conserved protein Function unknown 150391030 Common - metal dependent phosphohydrolase Amet_3286 120 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150389766 Common - two component transcriptional regulator, winged helix family Amet_1993 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150390348 Nonpathogen - hypothetical protein Amet_2586 1 None None None 150392249 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Amet_4568 120 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150388784 Common - hypothetical protein Amet_0954 23 COG4843 COG4843, Uncharacterized protein conserved in bacteria Function unknown 150389326 Common - transposase, IS111A/IS1328/IS1533 Amet_1524 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388373 Nonpathogen - hypothetical protein Amet_0536 1 None None None 150391790 Common - molybdopterin oxidoreductase Fe4S4 region Amet_4099 208 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 150390739 Common - Na+/solute symporter Amet_2980 142 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 150389636 Nonpathogen - hypothetical protein Amet_1857 1 None None None 150390164 Common - hypothetical protein Amet_2400 2 None None None 150388353 Common - phosphonate ABC transporter, ATPase subunit Amet_0516 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 150390529 Common - putative methyltransferase Amet_2768 214 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 150392461 Common - protein of unknown function DUF1256 Amet_4785 14 None None None 150388610 Common - 2'-5' RNA ligase Amet_0775 87 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 150391063 Common - peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin Amet_3325 39 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150391622 Common - transcriptional regulator, PadR-like family Amet_3917 11 COG1695 COG1695, Predicted transcriptional regulators Transcription 150391529 Common - Aldose 1-epimerase Amet_3800 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 150388796 Common - TRAP dicarboxylate transporter- DctP subunit Amet_0969 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150392000 Common - Shikimate/quinate 5-dehydrogenase Amet_4316 36 COG5322 COG5322, Predicted dehydrogenase General function prediction only 150392320 Common - nitroreductase Amet_4639 9 COG0778 NfnB, Nitroreductase Energy production and conversion 150391942 Common - glutaminyl-tRNA synthetase Amet_4254 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150388540 Nonpathogen - protein of unknown function DUF1292 Amet_0705 2 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150387943 Common - methyltransferase small Amet_0090 131 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 150388233 Nonpathogen - hypothetical protein Amet_0395 1 None None None 150391008 Nonpathogen - hypothetical protein Amet_3260 2 None None None 150389168 Common - putative CoA-substrate-specific enzyme activase Amet_1358 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 150388836 Common - major facilitator superfamily MFS_1 Amet_1009 97 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150391151 Common - fumarate hydratase Amet_3413 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 150391216 Nonpathogen - hypothetical protein Amet_3478 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150390355 Nonpathogen - hypothetical protein Amet_2593 1 None None None 150390179 Nonpathogen - hypothetical protein Amet_2415 1 None None None 150388254 Common - phage-associated protein, HI1409 family Amet_0416 17 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 150389312 Nonpathogen - hypothetical protein Amet_1508 1 None None None 150388752 Common - amidophosphoribosyltransferase Amet_0922 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 150390504 Common - tRNA (guanine-N1)-methyltransferase Amet_2743 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 150389534 Nonpathogen - hypothetical protein Amet_1751 1 None None None 150389654 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_1879 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390556 Common - pseudouridine synthase, RluA family Amet_2796 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150390777 Common - cytidine deaminase Amet_3027 117 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 150391553 Common - hypothetical protein Amet_3826 12 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 150391415 Common - glycoside hydrolase, family 18 Amet_3685 35 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 150392170 Common - ribosomal protein L10 Amet_4488 216 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 150392280 Common - spore germination B3 GerAC family protein Amet_4599 15 None None None 150388487 Common - argininosuccinate lyase Amet_0652 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 150389466 Common - protein of unknown function DUF218 Amet_1679 64 COG2949 SanA, Uncharacterized membrane protein Function unknown 150390247 Nonpathogen - hypothetical protein Amet_2484 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 150387930 Common - precorrin-6x reductase Amet_0077 80 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 150389398 Common - hypothetical protein Amet_1611 16 None None None 150390843 Nonpathogen - hypothetical protein Amet_3093 1 None None None 150392084 Common - transposase, IS4 family protein Amet_4401 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150391417 Common - alkylhydroperoxidase like protein, AhpD family Amet_3687 108 COG2128 COG2128, Uncharacterized conserved protein Function unknown 150389499 Common - protein of unknown function DUF523 Amet_1713 77 COG1683 COG1683, Uncharacterized conserved protein Function unknown 150388086 Common - plasmid pRiA4b ORF-3 family protein Amet_0243 11 None None None 150390105 Common - S-adenosylmethionine--tRNA-ribosyltransferase-isomerase Amet_2341 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 150390451 Common - ribosomal protein S2 Amet_2689 241 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 150388649 Common - hypothetical protein Amet_0814 11 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 150388467 Common - ATP-binding region, ATPase domain protein Amet_0631 17 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150388946 Common - Cupin 2, conserved barrel domain protein Amet_1125 36 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150390184 Common - phage-like element pbsx protein XkdK Amet_2420 5 None None None 150387994 Common - hypothetical protein Amet_0145 4 None None None 150388958 Common - histidine kinase internal region Amet_1137 104 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150388494 Common - methyl-accepting chemotaxis sensory transducer Amet_0659 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150388452 Common - MATE efflux family protein Amet_0616 101 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150390089 Common - amino acid carrier protein Amet_2322 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 150392478 Nonpathogen - ribosomal protein L34 Amet_4802 1 None None None 150390470 Nonpathogen - hypothetical protein Amet_2708 1 None None None 150389158 Common - flavocytochrome c Amet_1348 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150389333 Nonpathogen - hypothetical protein Amet_1533 2 None None None 150388675 Common - hypothetical protein Amet_0840 2 None None None 150388740 Common - inosine-5'-monophosphate dehydrogenase Amet_0909 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 150387992 Common - hypothetical protein Amet_0143 8 None None None 150390219 Nonpathogen - hypothetical protein Amet_2455 3 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 150389140 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Amet_1328 92 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 150391175 Common - Collagen triple helix repeat Amet_3437 3 None None None 150389096 Common - Accessory gene regulator B Amet_1281 7 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150391467 Common - conserved hypothetical protein 698 Amet_3738 118 COG2855 COG2855, Predicted membrane protein Function unknown 150392214 Common - coenzyme A transferase Amet_4532 106 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 150390533 Common - protein of unknown function DUF322 Amet_2772 42 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 150392425 Common - protein of unknown function DUF163 Amet_4749 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 150390928 Nonpathogen - hypothetical protein Amet_3180 1 None None None 150387946 Common - polynucleotide adenylyltransferase/metal dependent phosphohydrolase Amet_0093 183 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 150388473 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Amet_0638 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150388609 Common - hypothetical protein Amet_0774 10 None None None 150391381 Nonpathogen - hypothetical protein Amet_3649 1 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 150391865 Common - hypothetical protein Amet_4174 3 None None None 150388972 Common - hypothetical protein Amet_1151 11 COG5663 COG5663, Uncharacterized conserved protein Function unknown 150389776 Common - hypothetical protein Amet_2003 4 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 150390390 Nonpathogen - hypothetical protein Amet_2628 1 None None None 150388492 Common - CBS domain containing protein Amet_0657 6 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 150389948 Common - 60 kDa inner membrane insertion protein Amet_2179 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 150391028 Common - Catalase Amet_3282 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 150391141 Common - acetolactate synthase, small subunit Amet_3403 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 150389397 Common - putative transcriptional regulator Amet_1610 17 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 150390596 Common - phage portal protein, SPP1 Amet_2836 10 None None None 150389274 Common - Cobyrinic acid a,c-diamide synthase Amet_1465 36 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150390249 Nonpathogen - hypothetical protein Amet_2486 1 None None None 150388245 Common - Exopolysaccharide biosynthesis protein Amet_0407 16 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150390922 Common - pseudouridine synthase, RluA family Amet_3173 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150390740 Nonpathogen - hypothetical protein Amet_2981 1 None None None 150388456 Common - Accessory gene regulator B Amet_0620 6 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150389584 Nonpathogen - hypothetical protein Amet_1804 1 None None None 150390234 Common - O-methyltransferase, family 3 Amet_2470 113 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 150389106 Common - glucuronate isomerase Amet_1291 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 150389174 Common - small acid-soluble spore protein, alpha/beta type Amet_1364 13 None None None 150389601 Common - hypothetical protein Amet_1821 3 None None None 150388010 Common - polysaccharide biosynthesis protein Amet_0163 31 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150389954 Nonpathogen - hypothetical protein Amet_2185 1 None None None 150392254 Common - Xanthine/uracil/vitamin C permease Amet_4573 139 COG2252 COG2252, Permeases General function prediction only 150392436 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Amet_4760 151 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150388536 Common - protein of unknown function DUF368 Amet_0701 50 COG2035 COG2035, Predicted membrane protein Function unknown 150388227 Common - Uncharacterized ATPase putative transposase Amet_0389 15 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 150391013 Nonpathogen - hypothetical protein Amet_3265 1 None None None 150390660 Nonpathogen - hypothetical protein Amet_2900 1 COG1715 Mrr, Restriction endonuclease Defense mechanisms 150388279 Common - phage integrase domain protein SAM domain protein Amet_0441 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150392055 Nonpathogen - hypothetical protein Amet_4371 1 None None None 150389236 Nonpathogen - hypothetical protein Amet_1427 1 None None None 150390364 Common - primosome, DnaD subunit Amet_2602 4 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150391900 Common carB carbamoyl phosphate synthase large subunit Amet_4210 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 150390984 Common - hypothetical protein Amet_3236 7 COG0701 COG0701, Predicted permeases General function prediction only 150388645 Common - ABC transporter related Amet_0810 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150390672 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2912 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391884 Common - glycoside hydrolase, family 4 Amet_4194 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150389804 Common - periplasmic zinc transporter/adhesin B precursor Amet_2032 4 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150391964 Nonpathogen - hypothetical protein Amet_4276 1 None None None 150389110 Common - ABC transporter related Amet_1295 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150388709 Nonpathogen - hypothetical protein Amet_0877 1 None None None 150391309 Common - phosphoglyceromutase Amet_3577 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 150388169 Nonpathogen - hypothetical protein Amet_0329 1 None None None 150388289 Nonpathogen - Zn-finger containing protein Amet_0451 2 None None None 150391878 Common - PTS system, lactose/cellobiose family IIC subunit Amet_4187 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150390468 Common - flagellar biosynthetic protein FliQ Amet_2706 128 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 150389665 Nonpathogen - hypothetical protein Amet_1890 1 None None None 150389870 Common - hypothetical protein Amet_2100 7 COG5423 COG5423, Predicted metal-binding protein Function unknown 150390310 Nonpathogen - hypothetical protein Amet_2547 1 None None None 150389423 Common - potassium uptake protein, TrkH family Amet_1636 118 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 150389101 Common - Resolvase, N-terminal domain Amet_1286 117 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150388702 Common - hypothetical protein Amet_0867 18 None None None 150388185 Common - hypothetical protein Amet_0345 3 None None None 150390026 Common - GCN5-related N-acetyltransferase Amet_2258 93 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150387966 Nonpathogen - hypothetical protein Amet_0115 3 None None None 150390877 Common - membrane-bound metal-dependent hydrolase Amet_3128 19 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 150389498 Common - MutS2 family protein Amet_1712 200 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150391929 Common - hypothetical protein Amet_4239 5 None None None 150389753 Common - membrane bound O-acyl transferase, MBOAT family protein Amet_1980 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 150391408 Common - RelA/SpoT domain protein Amet_3678 89 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 150389885 Common - transcriptional regulator, XRE family Amet_2116 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 150388428 Common - xylulokinase Amet_0591 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 150390342 Common - YqaS Amet_2580 5 COG5484 COG5484, Uncharacterized conserved protein Function unknown 150388042 Common - nucleotidyltransferase substrate binding protein, HI0074 family Amet_0195 34 None None None 150389516 Nonpathogen - hypothetical protein Amet_1730 1 None None None 150392189 Common - PilT protein domain protein Amet_4507 47 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 150388527 Common - Formyl-CoA transferase Amet_0692 117 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 150389667 Nonpathogen - hypothetical protein Amet_1892 1 None None None 150391366 Common - pyridoxal phosphate-dependent acyltransferase, putative Amet_3634 192 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 150389916 Common - hypothetical protein Amet_2147 4 None None None 150389642 Nonpathogen - hypothetical protein Amet_1866 1 None None None 150391837 Common - Outer membrane lipoprotein-sorting protein-like protein Amet_4146 8 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 150390116 Common - adenine phosphoribosyltransferase Amet_2352 174 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 150391745 Common - hypothetical protein Amet_4053 3 None None None 150390564 Common - alanine racemase domain protein Amet_2804 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 150390449 Common - uridylate kinase Amet_2687 230 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 150389826 Common - hypothetical protein Amet_2055 115 COG0439 AccC, Biotin carboxylase Lipid metabolism 150391474 Common - gamma-glutamyltransferase Amet_3745 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 150392200 Common - hypothetical protein Amet_4518 17 COG0700 SpmB, Uncharacterized membrane protein Function unknown 150388515 Common - Alcohol dehydrogenase, zinc-binding domain protein Amet_0680 185 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 150390205 Common - conserved hypothetical cytosolic protein Amet_2441 3 None None None 150391306 Common hppA membrane-bound proton-translocating pyrophosphatase Amet_3574 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 150388025 Common - S-layer domain protein Amet_0178 19 None None None 150388123 Nonpathogen - hypothetical protein Amet_0281 1 None None None 150392173 Common - NusG antitermination factor Amet_4491 215 COG0250 NusG, Transcription antiterminator Transcription 150389387 Nonpathogen - hypothetical protein Amet_1598 5 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150388619 Common - flagellar protein FlaG protein Amet_0784 30 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 150389811 Common - ABC transporter related Amet_2039 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389682 Common - transcriptional regulator, TetR family Amet_1908 11 COG1309 AcrR, Transcriptional regulator Transcription 150392180 Common thyX FAD-dependent thymidylate synthase Amet_4498 61 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 150392116 Nonpathogen - hypothetical protein Amet_4434 1 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150389529 Nonpathogen - hypothetical protein Amet_1745 2 None None None 150389137 Common - hypothetical protein Amet_1325 6 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 150390412 Common - putative agmatinase Amet_2650 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 150387928 Common - cobalamin (vitamin B12) biosynthesis CbiG protein Amet_0075 90 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 150392413 Nonpathogen - hypothetical protein Amet_4737 3 COG5578 COG5578, Predicted integral membrane protein Function unknown 150389119 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Amet_1304 201 COG0281 SfcA, Malic enzyme Energy production and conversion 150390662 Nonpathogen - hypothetical protein Amet_2902 1 None None None 150391431 Nonpathogen - hypothetical protein Amet_3701 10 None None None 150387865 Nonpathogen - hypothetical protein Amet_0012 1 None None None 150388320 Common - peptidase M20 Amet_0483 30 COG4187 RocB, Arginine degradation protein (predicted deacylase) Amino acid transport and metabolism 150390519 Common - 3-oxoacyl-(acyl carrier protein) synthase III Amet_2758 204 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150389441 Common - SNARE associated Golgi protein Amet_1654 71 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150391443 Common - protein of unknown function DUF833 Amet_3713 44 COG3332 COG3332, Uncharacterized conserved protein Function unknown 150388764 Common - TrpR like protein, YerC/YecD Amet_0934 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 150390522 Common - ribosomal protein L32 Amet_2761 92 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 150389346 Common - putative transcriptional regulator, MerR family Amet_1552 20 COG0789 SoxR, Predicted transcriptional regulators Transcription 150389454 Common - CRISPR-associated protein Cas1 Amet_1667 97 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150389696 Nonpathogen - hypothetical protein Amet_1922 1 None None None 150388626 Common - peptide chain release factor 2 Amet_0791 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 150390106 Common - queuine tRNA-ribosyltransferase Amet_2342 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 150389549 Nonpathogen - hypothetical protein Amet_1767 1 None None None 150392012 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Amet_4328 228 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150390848 Nonpathogen - glutaredoxin Amet_3098 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 150391204 Common - Ferritin, Dps family protein Amet_3466 103 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 150391848 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Amet_4157 54 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 150390283 Common - hypothetical protein Amet_2520 12 None None None 150390333 Common - hypothetical protein Amet_2571 2 None None None 150389598 Nonpathogen - hypothetical protein Amet_1818 1 None None None 150389978 Common - pyruvate formate-lyase activating enzyme Amet_2210 101 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150392420 Common - ABC transporter related Amet_4744 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150390761 Common - transposase, IS4 family protein Amet_3010 17 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 150391271 Common - response regulator receiver protein Amet_3535 226 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150392127 Common - cobalt transport protein Amet_4445 108 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150388993 Nonpathogen - hypothetical protein Amet_1175 1 None None None 150392398 Common - binding-protein-dependent transport systems inner membrane component Amet_4720 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389309 Common - ubiquitin-associated domain-containing protein Amet_1505 7 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 150389660 Common - Bile acid:sodium symporter Amet_1885 132 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 150391261 Common - nitrogenase iron protein Amet_3524 78 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 150390798 Common - chaperone protein DnaK Amet_3048 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 150391625 Common - BAAT/Acyl-CoA thioester hydrolase-like protein Amet_3920 19 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 150390602 Nonpathogen - hypothetical protein Amet_2842 1 None None None 150388990 Common - putative CoA-substrate-specific enzyme activase Amet_1171 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 150392028 Common - hypothetical protein Amet_4344 4 None None None 150391056 Common - binding-protein-dependent transport systems inner membrane component Amet_3318 157 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150391972 Common - protein of unknown function UPF0150 Amet_4285 13 COG1598 COG1598, Uncharacterized conserved protein Function unknown 150388055 Common - O-antigen polymerase Amet_0210 6 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 150390765 Common - protein of unknown function DUF156 Amet_3015 103 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 150389844 Common - Extracellular ligand-binding receptor Amet_2074 151 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 150388576 Common - hypothetical protein Amet_0741 5 None None None 150389867 Common - cobalamin B12-binding domain protein Amet_2097 166 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 150390715 Nonpathogen - hypothetical protein Amet_2955 7 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 150391937 Nonpathogen - hypothetical protein Amet_4249 3 None None None 150388386 Common - phospholipase C zinc-binding protein Amet_0549 7 None None None 150389578 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_1798 151 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150389358 Common - cell cycle protein Amet_1566 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150389553 Common - integral membrane sensor signal transduction histidine kinase Amet_1771 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150392086 Common - MazG nucleotide pyrophosphohydrolase Amet_4403 25 COG1694 MazG, Predicted pyrophosphatase General function prediction only 150390781 Common - protein of unknown function UPF0054 Amet_3031 213 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 150391654 Common - two component transcriptional regulator, winged helix family Amet_3956 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150389028 Nonpathogen - hypothetical protein Amet_1210 1 None None None 150389988 Common - stage V sporulation protein AD Amet_2220 15 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150392369 Nonpathogen - hypothetical protein Amet_4691 2 None None None 150388394 Common - glycerol kinase Amet_0557 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 150391578 Nonpathogen - hypothetical protein Amet_3853 1 None None None 150389305 Common - ABC transporter related Amet_1501 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150389479 Nonpathogen - hypothetical protein Amet_1693 1 None None None 150388879 Common - Resolvase, N-terminal domain Amet_1056 46 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150389255 Common - hydroxylamine reductase Amet_1446 76 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150391897 Common - orotate phosphoribosyltransferase Amet_4207 177 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 150387860 Common - DNA gyrase, A subunit Amet_0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 150391295 Common - two component transcriptional regulator, LytTR family Amet_3563 119 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150391342 Common - 5'-Nucleotidase domain protein Amet_3610 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150388361 Common - cobalt transport protein Amet_0524 53 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150388298 Common - oxidoreductase domain protein Amet_0460 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150391041 Common - protein of unknown function DUF450 Amet_3300 105 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 150390066 Common - peptidase M50 Amet_2299 87 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 150391502 Common - transport system permease protein Amet_3773 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150390551 Common - hypothetical protein Amet_2791 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 150388525 Common - cyclase family protein Amet_0690 71 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 150390663 Common - hypoxanthine phosphoribosyltransferase Amet_2903 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 150391552 Common - microcompartments protein Amet_3825 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150390397 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_2635 54 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150390272 Common - hemolysin A Amet_2509 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 150389409 Common - amidohydrolase Amet_1622 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150390759 Common - transcriptional regulator, TetR family Amet_3008 26 COG1309 AcrR, Transcriptional regulator Transcription 150389896 Nonpathogen - hypothetical protein Amet_2127 1 None None None 150391748 Common - type I site-specific deoxyribonuclease, HsdR family Amet_4056 134 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 150388799 Common - HAD-superfamily hydrolase, subfamily IIA Amet_0972 117 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 150390030 Common - HAD-superfamily hydrolase, subfamily IB (PSPase-like) Amet_2262 146 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 150392096 Nonpathogen - hypothetical protein Amet_4414 1 None None None 150388531 Common - anion transporter Amet_0696 139 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 150392053 Common - hypothetical protein Amet_4369 8 None None None 150388136 Common - putative transcriptional regulator, TetR family Amet_0294 14 COG1309 AcrR, Transcriptional regulator Transcription 150388801 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Amet_0974 182 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150389930 Common - dihydropteroate synthase Amet_2161 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 150392403 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_4725 41 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 150391586 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Amet_3863 103 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150390629 Common - Sporulation protein YlmC/YmxH Amet_2869 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 150391805 Common - dihydroxyacetone kinase, DhaK subunit Amet_4114 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 150387894 Common - Amidohydrolase 3 Amet_0041 54 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 150388197 Common - hypothetical protein Amet_0357 5 None None None 150389414 Common - putative cold-shock DNA-binding domain protein Amet_1627 182 COG1278 CspC, Cold shock proteins Transcription 150389070 Common - dihydrolipoamide dehydrogenase Amet_1254 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 150389078 Common - PfkB domain protein Amet_1262 134 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150390408 Common - hypothetical protein Amet_2646 10 None None None 150389200 Common - protein of unknown function DUF606 Amet_1390 3 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 150388013 Common - RNA-binding S4 domain protein Amet_0166 78 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 150388230 Common - hypothetical protein Amet_0392 2 None None None 150390840 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Amet_3090 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150388109 Common - Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Amet_0266 76 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150391763 Common dnaE DNA polymerase III DnaE Amet_4071 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 150392137 Common - hypothetical protein Amet_4455 6 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 150390990 Common - methyl-accepting chemotaxis sensory transducer Amet_3242 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150390207 Common - membrane spanning protein Amet_2443 2 None None None 150390973 Common - citrate lyase subunit gamma Amet_3225 26 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 150391675 Common - peptidase M23B Amet_3980 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150390091 Common - selenocysteine-specific translation elongation factor Amet_2324 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 150392007 Common - integral membrane sensor signal transduction histidine kinase Amet_4323 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150388651 Nonpathogen - hypothetical protein Amet_0816 1 None None None 150390098 Common - protein of unknown function DUF378 Amet_2334 24 COG2155 COG2155, Uncharacterized conserved protein Function unknown 150392376 Common - RNA-binding S4 domain protein Amet_4698 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150387901 Common - SNARE associated Golgi protein Amet_0048 89 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150388260 Common - hypothetical protein Amet_0422 3 None None None 150392242 Common - putative tryptophan transport protein Amet_4561 6 None None None 150389034 Common - AzlC family protein Amet_1216 106 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 150390996 Nonpathogen - hypothetical protein Amet_3248 1 None None None 150389113 Common - beta-lactamase domain protein Amet_1298 123 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 150390655 Nonpathogen - hypothetical protein Amet_2895 1 None None None 150392450 Nonpathogen - sigmaK-factor processing regulatory BofA Amet_4774 3 None None None 150389417 Common - hypothetical protein Amet_1630 12 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 150389846 Common - inner-membrane translocator Amet_2076 137 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 150390724 Common - Citrate carrier protein Amet_2964 32 COG3493 CitS, Na+/citrate symporter Energy production and conversion 150392273 Common - Sporulation stage II, protein R Amet_4592 15 None None None 150390860 Common - protein of unknown function DUF606 Amet_3111 34 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 150388731 Common - glycoside hydrolase, family 28 Amet_0899 30 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 150392338 Common - ABC transporter, transmembrane region Amet_4658 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150389259 Common - Pirin domain protein Amet_1450 147 COG1741 COG1741, Pirin-related protein General function prediction only 150391886 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Amet_4196 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150390125 Common - UBA/THIF-type NAD/FAD binding protein Amet_2361 181 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 150391883 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Amet_4193 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150389377 Common - transcriptional regulator, PadR-like family Amet_1588 38 COG1695 COG1695, Predicted transcriptional regulators Transcription 150390492 Common - transposase Amet_2731 6 None None None 150391234 Common - Adenylyl-sulfate kinase Amet_3496 145 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 150390369 Nonpathogen - hypothetical protein Amet_2607 1 None None None 150392428 Common - beta-lactamase domain protein Amet_4752 62 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 150387892 Common - acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase Amet_0039 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 150391269 Common - TRAP dicarboxylate transporter, DctP subunit Amet_3533 101 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150388643 Common - putative metalloendopeptidase, glycoprotease family Amet_0808 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 150389888 Common - hypothetical protein Amet_2119 64 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150389091 Common - multi-sensor signal transduction histidine kinase Amet_1275 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390933 Common - protein of unknown function DUF1538 Amet_3185 23 None None None 150391452 Common - putative transcriptional regulator, Crp/Fnr family Amet_3722 182 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150391590 Common - ABC transporter related Amet_3867 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150389773 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_2000 151 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150388159 Common - putative transaldolase Amet_0319 158 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150388066 Common - DNA protecting protein DprA Amet_0221 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 150391709 Nonpathogen - hypothetical protein Amet_4017 1 None None None 150388062 Common - cell envelope-related transcriptional attenuator Amet_0217 63 COG1316 LytR, Transcriptional regulator Transcription 150388671 Nonpathogen - hypothetical protein Amet_0836 1 None None None 150391402 Common - pseudouridine synthase Amet_3672 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150389995 Common - hypothetical protein Amet_2227 9 None None None 150390437 Common - protein of unknown function DUF448 Amet_2675 46 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 150392239 Common - metallophosphoesterase Amet_4558 106 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150389100 Common - GerA spore germination protein Amet_1285 15 None None None 150390466 Common - flagellar biosynthetic protein FlhB Amet_2704 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 150390373 Nonpathogen - hypothetical protein Amet_2611 1 None None None 150391914 Common - stage V sporulation protein AD Amet_4224 15 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150390142 Nonpathogen - hypothetical protein Amet_2378 2 None None None 150390569 Common - binding-protein-dependent transport systems inner membrane component Amet_2809 182 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 150388288 Nonpathogen - hypothetical protein Amet_0450 1 None None None 150391760 Common - pyruvate kinase Amet_4068 234 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 150392278 Common - spore germination protein Amet_4597 21 None None None 150389567 Common - type III restriction protein, res subunit Amet_1785 119 COG4951 COG4951, Uncharacterized protein conserved in bacteria Function unknown 150389604 Nonpathogen - hypothetical protein Amet_1824 2 None None None 150388118 Nonpathogen - hypothetical protein Amet_0275 1 None None None 150389011 Common - Transcriptional regulator IclR-like protein Amet_1193 122 COG1414 IclR, Transcriptional regulator Transcription 150391308 Common - Phosphopyruvate hydratase Amet_3576 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 150390430 Common - ribosomal protein S15 Amet_2668 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 150391921 Common - protein of unknown function DUF124 Amet_4231 72 COG2013 COG2013, Uncharacterized conserved protein Function unknown 150388295 Common - ABC transporter related Amet_0457 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150388393 Common - Altronate dehydratase Amet_0556 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 150390597 Common - hypothetical protein Amet_2837 14 None None None 150390704 Common - alpha amylase, catalytic region Amet_2944 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150391263 Nonpathogen - hypothetical protein Amet_3527 1 None None None 150392382 Nonpathogen - Domain of unknown function DUF1850 Amet_4704 4 COG4729 COG4729, Uncharacterized conserved protein Function unknown 150389734 Nonpathogen - hypothetical protein Amet_1961 1 None None None 150389785 Nonpathogen - Fe-S cluster domain protein Amet_2012 17 COG4871 COG4871, Uncharacterized protein conserved in archaea Function unknown 150388790 Nonpathogen - hypothetical protein Amet_0962 2 None None None 150391851 Nonpathogen - hypothetical protein Amet_4160 3 None None None 150389278 Common - Silent information regulator protein Sir2 Amet_1469 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 150390507 Common rpsP 30S ribosomal protein S16 Amet_2746 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 150390960 Common - GerA spore germination protein Amet_3212 15 None None None 150389659 Common - peptidase S58, DmpA Amet_1884 55 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150391978 Common - hypothetical protein Amet_4292 37 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150390644 Common - UDP-N-acetylmuramyl-tripeptide synthetase Amet_2884 214 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150390814 Common - hypothetical protein Amet_3064 57 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150391549 Common - microcompartments protein Amet_3822 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150388847 Common - GTP cyclohydrolase II Amet_1020 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 150388722 Common - export-related chaperone CsaA Amet_0890 103 COG0073 ARC1, EMAP domain General function prediction only 150388246 Common - cell wall hydrolase/autolysin Amet_0408 37 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150389877 Nonpathogen - hypothetical protein Amet_2107 1 None None None 150391563 Common - Formate C-acetyltransferase Amet_3836 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150389797 Common - acetyl-CoA decarbonylase/synthase complex subunit delta Amet_2025 20 COG2069 CdhD, CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) Energy production and conversion 150391725 Common - phage Terminase Amet_4033 49 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 150389141 Common - cytoplasmic chaperone TorD family protein Amet_1329 33 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 150392163 Common - translation elongation factor G Amet_4481 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150390035 Nonpathogen - hypothetical protein Amet_2267 3 None None None 150391491 Common - ABC transporter related Amet_3762 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150392333 Nonpathogen - Desulfoferrodoxin, ferrous iron-binding region Amet_4653 20 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 150391938 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_4250 142 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150391131 Common - Threonyl/alanyl tRNA synthetase, SAD Amet_3393 226 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150390895 Nonpathogen - hypothetical protein Amet_3146 1 None None None 150388507 Common - hypothetical protein Amet_0672 14 COG0730 COG0730, Predicted permeases General function prediction only 150389384 Common - phage integrase family protein Amet_1595 13 None None None 150388925 Common - Ppx/GppA phosphatase Amet_1104 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 150390879 Common - transposase, IS4 family protein Amet_3130 13 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150388150 Common - hypothetical protein Amet_0309 14 None None None 150388124 Common - efflux transporter, RND family, MFP subunit Amet_0282 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150389947 Common - hypothetical protein Amet_2178 4 None None None 150392198 Common - histidinol-phosphate aminotransferase Amet_4516 241 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150388031 Nonpathogen - copper amine oxidase domain protein Amet_0184 9 None None None 150388602 Common - sodium/glutamate symporter Amet_0767 56 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 150390005 Common - phage integrase family protein Amet_2237 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150388331 Nonpathogen - hypothetical protein Amet_0494 1 None None None 150389253 Common - hypothetical protein Amet_1444 12 None None None 150390846 Common - molybdopterin oxidoreductase Amet_3096 234 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 150392013 Nonpathogen - protein of unknown function UPF0016 Amet_4329 6 COG2119 COG2119, Predicted membrane protein Function unknown 150389214 Common - cation diffusion facilitator family transporter Amet_1404 204 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150391523 Common - xylulokinase Amet_3794 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 150392392 Common - protein of unknown function DUF6, transmembrane Amet_4714 155 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150390621 Common - hypothetical protein Amet_2861 6 None None None 150389265 Nonpathogen - hypothetical protein Amet_1456 1 None None None 150388284 Nonpathogen - hypothetical protein Amet_0446 1 None None None 150388735 Nonpathogen - hypothetical protein Amet_0904 6 None None None 150389611 Common - arsenite-activated ATPase ArsA Amet_1831 94 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 150389589 Nonpathogen - hypothetical protein Amet_1809 1 None None None 150390042 Common - hypothetical protein Amet_2275 8 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 150388747 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Amet_0917 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 150389013 Common - Asp/Glu racemase Amet_1195 47 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 150388092 Common - methyl-accepting chemotaxis sensory transducer Amet_0249 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150390043 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Amet_2276 37 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 150388718 Common - transcriptional regulator, XRE family Amet_0886 28 COG1476 COG1476, Predicted transcriptional regulators Transcription 150388079 Common - ABC-2 type transporter Amet_0235 152 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150389649 Common - transcriptional regulator, MarR family Amet_1873 44 COG1846 MarR, Transcriptional regulators Transcription 150392049 Common - phage-associated protein, HI1409 family Amet_4365 17 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 150389746 Common - hypothetical protein Amet_1973 27 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150388238 Nonpathogen - hypothetical protein Amet_0400 1 None None None 150391026 Common - Methyltransferase type 11 Amet_3279 90 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150391655 Common - protein of unknown function DUF1232 Amet_3957 26 COG3339 COG3339, Uncharacterized conserved protein Function unknown 150388142 Common - hypothetical protein Amet_0300 19 None None None 150391542 Common - hypothetical protein Amet_3814 7 COG0456 RimI, Acetyltransferases General function prediction only 150391084 Common - (2Fe-2S)-binding domain protein Amet_3346 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 150391100 Common - hypothetical protein Amet_3362 3 None None None 150388414 Common - imidazoleglycerol phosphate synthase, cyclase subunit Amet_0577 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 150388091 Common - response regulator receiver protein Amet_0248 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 150390638 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Amet_2878 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 150389818 Common - binding-protein-dependent transport systems inner membrane component Amet_2047 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388006 Nonpathogen - hypothetical protein Amet_0159 5 None None None 150391089 Nonpathogen - Abortive infection protein Amet_3351 1 None None None 150387864 Nonpathogen - hypothetical protein Amet_0011 1 None None None 150389698 Nonpathogen - hypothetical protein Amet_1924 1 None None None 150388306 Nonpathogen - hypothetical protein Amet_0468 1 None None None 150389561 Common - transcriptional regulator, TetR family Amet_1779 81 COG1309 AcrR, Transcriptional regulator Transcription 150391220 Common - type II secretion system protein E Amet_3482 218 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 150389163 Common - Xanthine/uracil/vitamin C permease Amet_1353 41 COG2252 COG2252, Permeases General function prediction only 150390822 Common - phosphatidylglycerophosphatase A Amet_3072 13 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 150389195 Nonpathogen - hypothetical protein Amet_1385 1 None None None 150389493 Common - 30S ribosomal protein S4 Amet_1707 239 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 150391227 Common - hypothetical protein Amet_3489 24 None None None 150390786 Nonpathogen - hypothetical protein Amet_3036 1 None None None 150388215 Common - UTP-glucose-1-phosphate uridylyltransferase Amet_0375 234 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150388312 Common - Mandelate racemase/muconate lactonizing protein Amet_0475 151 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 150391301 Nonpathogen - hypothetical protein Amet_3569 1 None None None 150391177 Common - UDP-glucose/GDP-mannose dehydrogenase Amet_3439 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 150389040 Nonpathogen - hypothetical protein Amet_1222 1 None None None 150388966 Common - hypothetical protein Amet_1145 3 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 150391048 Common - TrkA-N domain protein Amet_3309 101 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 150391181 Common - spore protein Amet_3443 12 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 150390741 Common - membrane protein-like protein Amet_2982 7 COG4907 COG4907, Predicted membrane protein Function unknown 150391880 Common - glucokinase regulatory-like protein Amet_4189 85 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 150388892 Common - Chromate transporter Amet_1070 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 150390173 Common - hypothetical protein Amet_2409 6 None None None 150391504 Common - helix-turn-helix- domain containing protein, AraC type Amet_3775 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150389840 Common - PAS/PAC sensor hybrid histidine kinase Amet_2069 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391061 Common - ABC transporter related Amet_3323 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 150390483 Nonpathogen - flagellar export protein FliJ Amet_2721 4 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 150390880 Nonpathogen - hypothetical protein Amet_3131 1 None None None 150391239 Common - UBA/THIF-type NAD/FAD binding protein Amet_3501 214 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 150391753 Nonpathogen - hypothetical protein Amet_4061 1 None None None 150392288 Common - carbamate kinase Amet_4607 66 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 150389926 Common - glutamine amidotransferase of anthranilate synthase Amet_2157 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 150391353 Common - cobalamin 5'-phosphate synthase Amet_3621 88 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 150392144 Common - ribosomal protein L18 Amet_4462 219 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 150389532 Nonpathogen - hypothetical protein Amet_1749 1 None None None 150388402 Common - hypothetical protein Amet_0565 14 COG4492 PheB, ACT domain-containing protein General function prediction only 150391283 Common - SirA family protein Amet_3547 19 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 150388594 Common - flavocytochrome c Amet_0759 216 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150391390 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Amet_3658 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 150392312 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Amet_4631 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150389087 Nonpathogen - hypothetical protein Amet_1271 1 None None None 150390902 Common - protein of unknown function DUF583 Amet_3153 72 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 150392315 Common - tRNA pseudouridine synthase A Amet_4634 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 150390126 Common - positive regulator of sigma E, RseC/MucC Amet_2362 16 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 150390053 Common - Heptaprenyl diphosphate synthase component I Amet_2286 24 COG4769 COG4769, Predicted membrane protein Function unknown 150391090 Nonpathogen - hypothetical protein Amet_3352 2 None None None 150390584 Common - LemA family protein Amet_2824 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 150388023 Nonpathogen - hypothetical protein Amet_0176 1 None None None 150388742 Nonpathogen - hypothetical protein Amet_0911 2 None None None 150388952 Common - nickel ABC transporter, periplasmic nickel-binding protein Amet_1131 186 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150390999 Common - positive regulator of sigma E, RseC/MucC Amet_3251 3 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 150388218 Nonpathogen - hypothetical protein Amet_0379 2 None None None 150391635 Common - Catalase Amet_3934 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 150391289 Common - integral membrane sensor signal transduction histidine kinase Amet_3555 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390936 Common - RnfA-Nqr electron transport subunit Amet_3188 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 150390359 Nonpathogen - hypothetical protein Amet_2597 1 None None None 150390345 Common - putative sigma factor Amet_2583 3 None None None 150389651 Common - transcriptional regulator, RpiR family Amet_1876 61 COG1737 RpiR, Transcriptional regulators Transcription 150391437 Common - Cystathionine gamma-synthase Amet_3707 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150388581 Common - prevent-host-death family protein Amet_0746 16 None None None 150388050 Common - glycosyl transferase, group 1 Amet_0205 27 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150391369 Common - signal peptidase I Amet_3637 158 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150391392 Common - polar amino acid ABC transporter, inner membrane subunit Amet_3660 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150387967 Common - IS66 Orf2 family protein Amet_0116 49 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 150390087 Common - competence protein ComEA helix-hairpin-helix repeat protein Amet_2320 81 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 150391197 Common - hypothetical protein Amet_3459 5 None None None 150391536 Common - ABC transporter related Amet_3808 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150392193 Common - DNA repair protein RadA Amet_4511 223 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 150389596 Common - hypothetical protein Amet_1816 4 None None None 150389125 Nonpathogen - hypothetical protein Amet_1311 1 None None None 150391310 Common - Triose-phosphate isomerase Amet_3578 222 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 150391715 Common - hypothetical protein Amet_4023 5 None None None 150387887 Common - ribosomal protein S18 Amet_0034 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 150390135 Common - cobalamin B12-binding domain protein Amet_2371 28 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 150391682 Nonpathogen - hypothetical protein Amet_3989 1 None None None 150389765 Common - integral membrane sensor signal transduction histidine kinase Amet_1992 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150392293 Common - transcriptional regulator, MarR family Amet_4612 43 COG1846 MarR, Transcriptional regulators Transcription 150388387 Common - TRAP dicarboxylate transporter, DctP subunit Amet_0550 103 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150391314 Common - RNA polymerase, sigma 54 subunit, RpoN Amet_3582 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 150390685 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Amet_2925 183 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150389451 Common - CRISPR-associated protein, Csd1 family Amet_1664 14 None None None 150389313 Common - formylmethanofuran dehydrogenase, subunit E region Amet_1509 35 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 150391360 Common - endonuclease III Amet_3628 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 150388872 Common - hypothetical protein Amet_1047 68 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 150388040 Common - O-antigen polymerase Amet_0193 15 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 150391152 Common - Methylaspartate ammonia-lyase Amet_3414 15 COG3799 Mal, Methylaspartate ammonia-lyase Amino acid transport and metabolism 150392062 Nonpathogen - hypothetical protein Amet_4378 1 None None None 150391323 Common - selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family Amet_3591 10 None None None 150391240 Common - thiamine biosynthesis protein ThiS Amet_3502 25 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 150387911 Common - Glutamyl-tRNA reductase Amet_0058 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 150390636 Common - protein of unknown function DUF881 Amet_2876 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 150390745 Common - protein of unknown function DUF633 Amet_2991 32 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 150392323 Common - thiamineS protein Amet_4642 18 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 150390114 Common - ABC-1 domain protein Amet_2350 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 150390913 Common - diguanylate cyclase Amet_3164 161 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 150391944 Common - MATE efflux family protein Amet_4256 118 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150390578 Common - periplasmic sugar-binding protein Amet_2818 89 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150388196 Common - protein of unknown function DUF1694 Amet_0356 7 COG5506 COG5506, Uncharacterized conserved protein Function unknown 150390413 Common - transposase, IS4 family protein Amet_2651 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150387985 Common - 3D domain protein Amet_0136 40 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 150391349 Common - ABC transporter related Amet_3617 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150388685 Common - SMC domain protein Amet_0850 40 COG4938 COG4938, Uncharacterized conserved protein Function unknown 150388779 Common - conserved hypothetical protein 374 Amet_0949 28 COG0392 COG0392, Predicted integral membrane protein Function unknown 150387983 Common - hypothetical protein Amet_0134 4 None None None 150389109 Common - transcriptional regulator, GntR family Amet_1294 133 COG1802 GntR, Transcriptional regulators Transcription 150389064 Common - Hydroxyethylthiazole kinase Amet_1248 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 150390532 Common - Dak phosphatase Amet_2771 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 150387888 Common - YibE/F family protein Amet_0035 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150388453 Common - putative transcriptional regulator, MerR family Amet_0617 41 COG0789 SoxR, Predicted transcriptional regulators Transcription 150390837 Common - two component transcriptional regulator, winged helix family Amet_3087 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391125 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Amet_3387 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 150392477 Common - ribonuclease P protein component Amet_4801 80 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 150391057 Common - binding-protein-dependent transport systems inner membrane component Amet_3319 167 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150391531 Common - copper amine oxidase domain protein Amet_3803 24 COG4371 COG4371, Predicted membrane protein Function unknown 150388959 Common - response regulator receiver protein Amet_1138 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150388674 Common - phage protein Amet_0839 5 None None None 150389007 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Amet_1189 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 150392435 Nonpathogen - hypothetical protein Amet_4759 10 None None None 150388319 Common - ExsB family protein Amet_0482 74 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 150388465 Nonpathogen - hypothetical protein Amet_0629 1 None None None 150389150 Common - transcriptional regulator, TetR family Amet_1339 83 COG1309 AcrR, Transcriptional regulator Transcription 150389273 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Amet_1464 28 COG1433 COG1433, Uncharacterized conserved protein Function unknown 150388971 Common - transcriptional regulator, GntR family Amet_1150 96 COG2188 PhnF, Transcriptional regulators Transcription 150390929 Nonpathogen - hypothetical protein Amet_3181 1 None None None 150391038 Common - SNARE associated Golgi protein Amet_3297 46 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150388466 Nonpathogen - hypothetical protein Amet_0630 1 None None None 150392147 Common - ribosomal protein S14 Amet_4465 206 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 150390491 Common - GAF sensor signal transduction histidine kinase Amet_2729 201 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150388457 Nonpathogen - hypothetical protein Amet_0621 1 None None None 150388493 Nonpathogen - hypothetical protein Amet_0658 2 None None None 150389469 Nonpathogen - hypothetical protein Amet_1682 3 None None None 150387995 Common - AbgT putative transporter Amet_0146 48 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 150389641 Common - nitroreductase Amet_1863 154 COG0778 NfnB, Nitroreductase Energy production and conversion 150390849 Common - hypothetical protein Amet_3099 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 150392283 Nonpathogen - hypothetical protein Amet_4602 17 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 150388380 Common - YibE/F family protein Amet_0543 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150388495 Common - acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase Amet_0660 226 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 150388244 Common - 3D domain protein Amet_0406 14 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150388278 Nonpathogen - hypothetical protein Amet_0440 1 None None None 150389097 Common - Peptidylprolyl isomerase Amet_1282 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 150390289 Common - purine nucleoside phosphorylase Amet_2526 155 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 150391864 Common - hypothetical protein Amet_4173 3 None None None 150392097 Common - potassium uptake protein, TrkH family Amet_4415 122 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 150391382 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Amet_3650 164 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150392056 Nonpathogen - hypothetical protein Amet_4372 1 None None None 150389581 Nonpathogen - hypothetical protein Amet_1801 1 None None None 150388937 Common - flavodoxin Amet_1116 52 COG0716 FldA, Flavodoxins Energy production and conversion 150389233 Common - GCN5-related N-acetyltransferase Amet_1423 122 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150389714 Nonpathogen - hypothetical protein Amet_1941 1 None None None 150392197 Common - translation elongation factor G Amet_4515 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150392390 Common - hypothetical protein Amet_4712 2 None None None 150389745 Common - hypothetical protein Amet_1972 3 None None None 150388575 Common - DNA polymerase, beta domain protein region Amet_0740 22 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 150389480 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1694 125 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 150392061 Nonpathogen - hypothetical protein Amet_4377 1 None None None 150391322 Common - Betaine reductase Amet_3590 8 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150392304 Common - phosphate ABC transporter, inner membrane subunit PstC Amet_4623 229 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 150389708 Nonpathogen - hypothetical protein Amet_1935 1 None None None 150391142 Common - threonine dehydratase Amet_3404 212 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 150389703 Common - hypothetical protein Amet_1930 2 None None None 150389365 Nonpathogen - hypothetical protein Amet_1576 2 None None None 150388537 Common - PfkB domain protein Amet_0702 144 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150388910 Common - protein of unknown function DUF161 Amet_1088 30 COG2364 COG2364, Predicted membrane protein Function unknown 150390523 Common - protein of unknown function DUF177 Amet_2762 53 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 150390887 Common - transcriptional regulator, LysR family Amet_3138 189 COG0583 LysR, Transcriptional regulator Transcription 150389225 Common - hypothetical protein Amet_1415 18 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 150388072 Common - iron-containing alcohol dehydrogenase Amet_0227 177 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150389330 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Amet_1528 72 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 150390156 Nonpathogen - putative transcriptional regulator, XRE family Amet_2392 1 COG1396 HipB, Predicted transcriptional regulators Transcription 150392228 Common - hypothetical protein Amet_4546 4 None None None 150389396 Common - type I site-specific deoxyribonuclease, HsdR family Amet_1609 138 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 150389327 Common - phosphoenolpyruvate synthase Amet_1525 153 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150390583 Common - protein of unknown function DUF477 Amet_2823 85 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 150392192 Common - protein of unknown function DUF147 Amet_4510 30 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 150388778 Common - hypothetical protein Amet_0948 6 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 150387919 Common - hypothetical protein Amet_0066 10 None None None 150389308 Common - transcription activator, effector binding Amet_1504 111 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 150392305 Common - phosphate binding protein Amet_4624 160 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 150388420 Common - glycyl-radical enzyme activating protein family Amet_0583 67 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150391983 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Amet_4299 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 150388914 Nonpathogen - hypothetical protein Amet_1092 2 None None None 150389497 Common - polysaccharide deacetylase Amet_1711 98 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150389635 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_1856 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150387950 Common - peptidase S58, DmpA Amet_0097 56 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150391724 Nonpathogen - hypothetical protein Amet_4032 1 None None None 150392248 Common - adenine deaminase Amet_4567 82 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 150388176 Common - Sua5/YciO/YrdC/YwlC family protein Amet_0336 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 150388051 Common - UDP-glucose/GDP-mannose dehydrogenase Amet_0206 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 150389535 Nonpathogen - hypothetical protein Amet_1752 1 None None None 150390195 Common - phage-like element pbsx protein XkdT Amet_2431 3 None None None 150391901 Common - carbamoyl phosphate synthase small subunit Amet_4211 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 150389424 Common - TrkA-N domain protein Amet_1637 147 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 150392462 Nonpathogen - hypothetical protein Amet_4786 1 None None None 150388343 Common - pyruvate formate-lyase Amet_0506 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150391001 Common - YibE/F family protein Amet_3253 33 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150390793 Common - histidine triad (HIT) protein Amet_3043 233 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 150391813 Common - HPr kinase/phosphorylase Amet_4122 71 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 150388690 Nonpathogen - helix-turn-helix domain protein Amet_0855 1 None None None 150388119 Nonpathogen - hypothetical protein Amet_0276 1 None None None 150390869 Common - hypothetical protein Amet_3120 16 COG1291 MotA, Flagellar motor component Cell motility and secretion 150391466 Common - amidohydrolase Amet_3737 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150392268 Common - cyclase family protein Amet_4587 93 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 150389834 Common - binding-protein-dependent transport systems inner membrane component Amet_2063 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390557 Common - lipoprotein signal peptidase Amet_2797 199 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150392208 Common - hypothetical protein Amet_4526 20 None None None 150392171 Common - ribosomal protein L1 Amet_4489 242 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 150388255 Common - phage putative head morphogenesis protein, SPP1 gp7 family Amet_0417 17 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 150389510 Nonpathogen - GCN5-related N-acetyltransferase Amet_1724 4 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 150391108 Common - putative transcriptional regulator, XRE family Amet_3370 48 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 150391716 Common - phage protein, HK97 gp10 family Amet_4024 5 None None None 150391414 Nonpathogen - UspA Amet_3684 5 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150389347 Common - ABC transporter related Amet_1553 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150389925 Common - metal dependent phosphohydrolase Amet_2156 7 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150391352 Common - Phosphoglycerate mutase Amet_3620 193 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150392358 Nonpathogen - hypothetical protein Amet_4680 1 None None None 150389812 Common - transcriptional regulator, MarR family Amet_2040 12 COG1846 MarR, Transcriptional regulators Transcription 150390406 Nonpathogen - hypothetical protein Amet_2644 3 None None None 150392069 Nonpathogen - hypothetical protein Amet_4385 1 None None None 150388374 Common - beta-lactamase domain protein Amet_0537 224 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150391416 Common - Peptidoglycan-binding LysM Amet_3686 37 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 150391952 Common - YCII-related Amet_4264 7 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 150392414 Common - ABC transporter related Amet_4738 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 150389325 Common - acriflavin resistance protein Amet_1522 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150388087 Nonpathogen - hypothetical protein Amet_0244 1 None None None 150390248 Nonpathogen - hypothetical protein Amet_2485 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 150388635 Common - major facilitator superfamily MFS_1 Amet_0800 138 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150388866 Common - regulatory protein, LuxR Amet_1040 7 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 150391499 Common - major facilitator superfamily MFS_1 Amet_3770 173 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 150388648 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_0813 188 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 150391915 Common - Sporulation stage V, protein AC Amet_4225 15 None None None 150390590 Nonpathogen - hypothetical protein Amet_2830 1 None None None 150390178 Common - putative major capsid protein Amet_2414 2 None None None 150389722 Nonpathogen - hypothetical protein Amet_1949 1 None None None 150388486 Common - chorismate mutase Amet_0651 205 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 150389352 Common - putative signal transduction histidine kinase Amet_1558 61 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150391626 Nonpathogen - hypothetical protein Amet_3921 1 None None None 150388332 Nonpathogen - hypothetical protein Amet_0495 1 None None None 150389729 Common - hypothetical protein Amet_1956 2 None None None 150388765 Common - aspartate kinase I Amet_0935 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 150391979 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Amet_4293 29 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 150389959 Common - CRISPR-associated CXXC_CXXC protein Cst1 Amet_2190 5 None None None 150388625 Common secA preprotein translocase subunit SecA Amet_0790 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 150388670 Common - phage integrase family protein Amet_0835 147 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150390472 Common - flagellar motor switch protein Amet_2710 122 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 150389465 Common - glycogen/starch/alpha-glucan phosphorylase Amet_1678 134 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 150388984 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Amet_1164 94 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 150389159 Common - PfkB domain protein Amet_1349 35 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150390463 Common - Cobyrinic acid a,c-diamide synthase Amet_2701 233 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150391442 Common - two component transcriptional regulator, winged helix family Amet_3712 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150387861 Common - anti-sigma-factor antagonist Amet_0008 62 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 150389755 Common - cell wall hydrolase/autolysin Amet_1982 183 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150389000 Common - hypothetical protein Amet_1182 9 COG4720 COG4720, Predicted membrane protein Function unknown 150390107 Common - preprotein translocase, YajC subunit Amet_2343 91 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 150390282 Common - hypothetical protein Amet_2519 11 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 150389118 Common - response regulator receiver and unknown domain protein Amet_1303 222 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 150391642 Common - regulatory protein GntR, HTH Amet_3941 57 COG1725 COG1725, Predicted transcriptional regulators Transcription 150391209 Nonpathogen - S-layer domain protein Amet_3471 1 None None None 150388994 Common - hypothetical protein Amet_1176 15 None None None 150389552 Common - two component transcriptional regulator, winged helix family Amet_1770 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150390760 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Amet_3009 91 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150392040 Nonpathogen - hypothetical protein Amet_4356 1 None None None 150392233 Common - hypothetical protein Amet_4551 11 None None None 150391579 Common - IstB domain protein ATP-binding protein Amet_3854 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150391752 Common - RNA methyltransferase, TrmA family Amet_4060 210 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 150389481 Common - metallophosphoesterase Amet_1695 87 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150390325 Common - Peptidoglycan-binding LysM Amet_2563 37 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 150390815 Nonpathogen - hypothetical protein Amet_3065 2 None None None 150391482 Common - diguanylate cyclase and metal dependent phosphohydrolase Amet_3753 216 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150390910 Common - arginine deiminase Amet_3161 58 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 150392126 Common - tRNA pseudouridine synthase A Amet_4444 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 150387973 Nonpathogen - hypothetical protein Amet_0123 1 None None None 150389579 Nonpathogen - hypothetical protein Amet_1799 3 None None None 150388224 Nonpathogen - hypothetical protein Amet_0386 1 None None None 150391027 Common - Radical SAM domain protein Amet_3280 104 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150389868 Common - transcriptional regulator, GntR family Amet_2098 132 COG2188 PhnF, Transcriptional regulators Transcription 150388508 Common - glutamate 5-kinase Amet_0673 198 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 150390601 Nonpathogen - hypothetical protein Amet_2841 1 None None None 150392085 Common - protein of unknown function DUF542, ScdA domain protein Amet_4402 46 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 150392162 Common - elongation factor Tu Amet_4480 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 150391986 Nonpathogen - hypothetical protein Amet_4302 1 None None None 150390165 Nonpathogen - hypothetical protein Amet_2401 1 None None None 150391564 Common - microcompartments protein Amet_3837 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150390262 Common - hypothetical protein Amet_2499 10 None None None 150389906 Nonpathogen - hypothetical protein Amet_2137 1 None None None 150391706 Common - hypothetical protein Amet_4014 3 None None None 150389989 Common - Sporulation stage V, protein AE Amet_2221 15 None None None 150391296 Nonpathogen - hypothetical protein Amet_3564 1 None None None 150391274 Common - Nucleotidyl transferase Amet_3538 241 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 150392368 Nonpathogen - hypothetical protein Amet_4690 1 None None None 150389859 Common - sugar (Glycoside-Pentoside-Hexuronide) transporter Amet_2089 65 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150388137 Common - UTP-glucose-1-phosphate uridylyltransferase Amet_0295 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150389744 Nonpathogen - hypothetical protein Amet_1971 1 None None None 150391788 Common - Rubrerythrin Amet_4097 17 COG1633 COG1633, Uncharacterized conserved protein Function unknown 150387920 Common - hypothetical protein Amet_0067 12 COG2144 COG2144, Selenophosphate synthetase-related proteins General function prediction only 150388882 Common - regulatory protein, LuxR Amet_1060 30 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 150387925 Common - precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit Amet_0072 117 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 150390684 Nonpathogen - hypothetical protein Amet_2924 1 None None None 150391117 Common - carbamoyl-phosphate synthase, small subunit Amet_3379 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 150389027 Nonpathogen - hypothetical protein Amet_1209 1 None None None 150389976 Common - molybdenum cofactor synthesis domain Amet_2208 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 150392152 Common - ribosomal protein L29 Amet_4470 193 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 150388903 Common - Phosphoribosylanthranilate isomerase Amet_1081 196 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 150389969 Common - S-layer domain protein Amet_2201 9 None None None 150389819 Common - ABC transporter related Amet_2048 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390764 Common - flavodoxin Amet_3014 80 COG0716 FldA, Flavodoxins Energy production and conversion 150392029 Common - hypothetical protein Amet_4345 27 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150388360 Common - cobalt transport protein CbiM Amet_0523 23 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 150388008 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Amet_0161 158 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150389122 Common - transposase, IS4 family protein Amet_1307 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150388660 Common - transcriptional regulator, DeoR family Amet_0825 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150391165 Common - Serine-type D-Ala-D-Ala carboxypeptidase Amet_3427 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150388262 Nonpathogen - hypothetical protein Amet_0424 1 None None None 150388069 Common - putative DNA helicase Amet_0224 95 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 150388184 Common - hypothetical protein Amet_0344 8 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 150390279 Common - Thiamin pyrophosphokinase, catalytic region Amet_2516 19 COG4825 COG4825, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 150391050 Nonpathogen - hypothetical protein Amet_3311 1 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 150388829 Common - Methyltransferase type 12 Amet_1002 78 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150390918 Common - molybdenum cofactor synthesis domain Amet_3169 196 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 150391822 Common - cell division ATP-binding protein FtsE Amet_4131 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 150389134 Nonpathogen - hypothetical protein Amet_1322 1 None None None 150389890 Common - Abortive infection protein Amet_2121 2 None None None 150388429 Common - D-cysteine desulfhydrase Amet_0592 81 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 150387858 Common - hypothetical protein Amet_0005 9 None None None 150390920 Common - hypothetical protein Amet_3171 9 COG3081 COG3081, Nucleoid-associated protein General function prediction only 150390254 Common - hypothetical protein Amet_2491 10 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 150389666 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_1891 51 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150391279 Common - ABC-type metal ion transport system periplasmic component/surface adhesin-like protein Amet_3543 105 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150389304 Common - putative ABC antibiotics transporter Amet_1500 18 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 150390892 Nonpathogen - hypothetical protein Amet_3143 1 None None None 150389220 Common - Resolvase, N-terminal domain Amet_1410 46 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150390407 Common - Sporulation protein YtfJ Amet_2645 21 COG3874 COG3874, Uncharacterized conserved protein Function unknown 150391559 Common - hypothetical protein Amet_3832 4 COG4812 EutT, Ethanolamine utilization cobalamin adenosyltransferase Amino acid transport and metabolism 150391991 Common - hypothetical protein Amet_4307 15 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150391796 Common thiH thiamine biosynthesis protein ThiH Amet_4105 67 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 150388151 Common - Spore coat protein CotH Amet_0310 22 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 150389173 Nonpathogen - hypothetical protein Amet_1363 1 None None None 150390446 Common - undecaprenyl diphosphate synthase Amet_2684 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 150389460 Common - extracellular solute-binding protein, family 3 Amet_1673 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150389045 Common - cyanophycin synthetase Amet_1227 173 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150389434 Common - putative ATP-binding protein Amet_1647 17 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 150389754 Common - hypothetical protein Amet_1981 3 None None None 150390067 Common - Radical SAM domain protein Amet_2300 62 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150391838 Common - holo-acyl-carrier-protein synthase Amet_4147 96 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 150388038 Common - S-layer domain protein Amet_0191 11 None None None 150389492 Common - NAD-dependent epimerase/dehydratase Amet_1706 188 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150389668 Nonpathogen - hypothetical protein Amet_1893 1 None None None 150389590 Nonpathogen - hypothetical protein Amet_1810 1 None None None 150388820 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_0993 54 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 150391159 Nonpathogen - hypothetical protein Amet_3421 1 None None None 150392038 Common - hypothetical protein Amet_4354 5 None None None 150390654 Common - Sporulation lipoprotein YhcN/YlaJ Amet_2894 10 None None None 150388479 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Amet_0644 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150387944 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Amet_0091 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 150389825 Common - protein of unknown function DUF201 Amet_2054 74 COG0439 AccC, Biotin carboxylase Lipid metabolism 150391343 Common - protein of unknown function DUF362 Amet_3611 46 COG2006 COG2006, Uncharacterized conserved protein Function unknown 150391808 Common - inner-membrane translocator Amet_4117 152 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 150387958 Nonpathogen - hypothetical protein Amet_0105 1 None None None 150392117 Common - 7-cyano-7-deazaguanine reductase Amet_4435 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 150391520 Common - Non-specific serine/threonine protein kinase Amet_3791 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150390025 Common - transcriptional regulator, XRE family Amet_2257 68 COG1476 COG1476, Predicted transcriptional regulators Transcription 150391461 Nonpathogen - hypothetical protein Amet_3732 1 None None None 150388481 Common - Prephenate dehydrogenase Amet_0646 165 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 150388753 Common - phosphoribosylformylglycinamidine cyclo-ligase Amet_0923 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 150389069 Common - catalytic domain of components of various dehydrogenase complexes Amet_1253 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 150389020 Common - protein of unknown function DUF881 Amet_1202 20 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 150389050 Common - transposase, IS4 family protein Amet_1232 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150391963 Common - D-3-phosphoglycerate dehydrogenase Amet_4275 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150391215 Nonpathogen - hypothetical protein Amet_3477 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150391475 Common - hypothetical protein Amet_3746 29 COG3875 COG3875, Uncharacterized conserved protein Function unknown 150392404 Common - GCN5-related N-acetyltransferase Amet_4726 56 COG0456 RimI, Acetyltransferases General function prediction only 150388930 Common - transposase, IS4 family protein Amet_1109 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150392035 Common - phage tail tape measure protein, TP901 family Amet_4351 19 COG5280 COG5280, Phage-related minor tail protein Function unknown 150388339 Common - Dihydroxy-acid dehydratase Amet_0502 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150389816 Common - extracellular solute-binding protein, family 5 Amet_2045 178 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150390078 Common - cell envelope-related transcriptional attenuator Amet_2311 65 COG1316 LytR, Transcriptional regulator Transcription 150391207 Common - 6-phosphogluconate dehydrogenase-like protein Amet_3469 192 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 150390568 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Amet_2808 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 150390746 Nonpathogen - hypothetical protein Amet_2992 1 None None None 150390286 Common - tyrosine recombinase XerD Amet_2523 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150391081 Common - hypothetical protein Amet_3343 9 None None None 150391922 Common - Thiamine-phosphate diphosphorylase Amet_4232 130 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 150388020 Common - Sporulation stage II, protein E Amet_0173 36 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150390358 Common - hypothetical protein Amet_2596 6 None None None 150392353 Common - helix-turn-helix- domain containing protein, AraC type Amet_4675 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150390598 Nonpathogen - hypothetical protein Amet_2838 2 None None None 150387909 Common - cysteine synthase A Amet_0056 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150389968 Common - exonuclease-like protein Amet_2200 19 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 150391194 Common - 3-isopropylmalate dehydratase, small subunit Amet_3456 207 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 150388403 Common - Homoserine dehydrogenase Amet_0566 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 150392175 Common rpmG 50S ribosomal protein L33 Amet_4493 45 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 150390181 Nonpathogen - phage head-tail adaptor, putative Amet_2417 2 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 150388100 Common - microcompartments protein Amet_0257 15 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 150387982 Common - ABC transporter related Amet_0133 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150388727 Common - glycosyl hydrolase, family 88 Amet_0895 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 150390363 Common - IstB domain protein ATP-binding protein Amet_2601 96 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150391252 Common - pyruvate carboxyltransferase Amet_3515 219 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150392467 Common - parB-like partition protein Amet_4791 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150388812 Common - Arsenical resistance operon trans-acting repressor ArsD Amet_0985 31 None None None 150389467 Common - protein of unknown function DUF984 Amet_1680 36 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 150388112 Common - iron-containing alcohol dehydrogenase Amet_0269 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150390986 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_3238 53 COG0348 NapH, Polyferredoxin Energy production and conversion 150390163 Nonpathogen - hypothetical protein Amet_2399 1 None None None 150388437 Common - efflux transporter, RND family, MFP subunit Amet_0600 171 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150390742 Common - hypothetical protein Amet_2984 14 COG3410 COG3410, Uncharacterized conserved protein Function unknown 150388811 Common - arsenical-resistance protein Amet_0984 135 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 150388761 Common - binding-protein-dependent transport systems inner membrane component Amet_0931 176 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 150391645 Nonpathogen - membrane protein Amet_3944 1 COG1950 COG1950, Predicted membrane protein Function unknown 150391733 Common - hypothetical protein Amet_4041 8 None None None 150388970 Common - NADH dehydrogenase (quinone) Amet_1149 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 150390955 Nonpathogen - hypothetical protein Amet_3207 1 None None None 150388552 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_0717 7 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150391325 Common - Sarcosine reductase Amet_3593 8 None None None 150392329 Common - dUTPase Amet_4649 12 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 150388920 Common - two component transcriptional regulator, winged helix family Amet_1099 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150390567 Nonpathogen - hypothetical protein Amet_2807 1 None None None 150387974 Common - Accessory gene regulator B Amet_0124 2 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150388208 Common - protein of unknown function DUF214 Amet_0368 180 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150389252 Nonpathogen - hypothetical protein Amet_1443 2 None None None 150391387 Nonpathogen - hypothetical protein Amet_3655 3 None None None 150391537 Common - helix-turn-helix- domain containing protein, AraC type Amet_3809 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150387910 Common - Cysteine synthase Amet_0057 209 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150390133 Common - Pyridoxal-5'-phosphate-dependent protein, beta subunit Amet_2369 199 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150392188 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Amet_4506 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 150390611 Nonpathogen - hypothetical protein Amet_2851 1 None None None 150388370 Nonpathogen - hypothetical protein Amet_0533 1 None None None 150390218 Common - nitrogen-fixing NifU domain protein Amet_2454 159 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 150388553 Common - methyl-accepting chemotaxis sensory transducer Amet_0718 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150391438 Common - homoserine O-succinyltransferase Amet_3708 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 150392441 Common - Adenylosuccinate synthase Amet_4765 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 150392066 Nonpathogen - hypothetical protein Amet_4382 1 None None None 150389135 Common - regulatory protein GntR, HTH Amet_1323 118 COG1725 COG1725, Predicted transcriptional regulators Transcription 150390802 Common - GTP-binding protein LepA Amet_3052 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 150388163 Common rho transcription termination factor Rho Amet_0323 210 COG1158 Rho, Transcription termination factor Transcription 150390058 Common - rod shape-determining protein MreC Amet_2291 101 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 150390635 Common - protein of unknown function DUF881 Amet_2875 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 150389796 Common - Cobyrinic acid a,c-diamide synthase Amet_2024 35 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 150390138 Nonpathogen - hypothetical protein Amet_2374 1 None None None 150388518 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Amet_0683 121 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150390587 Nonpathogen - hypothetical protein Amet_2827 1 None None None 150389201 Common - putative membrane-spanning protein Amet_1391 19 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 150391087 Common - Abortive infection protein Amet_3349 3 None None None 150391483 Common - methyl-accepting chemotaxis sensory transducer Amet_3754 120 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150390998 Nonpathogen - hypothetical protein Amet_3250 1 None None None 150390727 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_2967 215 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150391680 Nonpathogen - hypothetical protein Amet_3987 1 None None None 150389039 Common - protein of unknown function DUF322 Amet_1221 39 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 150390084 Common - L-serine dehydratase, iron-sulfur-dependent, beta subunit Amet_2317 86 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 150391460 Common - putative hydrolase Amet_3731 82 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 150389573 Nonpathogen - hypothetical protein Amet_1792 1 None None None 150390245 Common - HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 Amet_2482 43 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 150392415 Common - extracellular solute-binding protein, family 1 Amet_4739 32 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150391033 Common - ABC transporter related Amet_3292 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 150391541 Common - hypothetical protein Amet_3813 9 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 150391698 Common - Recombinase Amet_4006 9 None None None 150391747 Common - protein of unknown function DUF45 Amet_4055 121 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 150391187 Nonpathogen - hypothetical protein Amet_3449 1 None None None 150388415 Common - phosphoribosyl-AMP cyclohydrolase Amet_0578 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 150390486 Common fliG flagellar motor switch protein G Amet_2724 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 150391093 Common - protein of unknown function UPF0150 Amet_3355 16 COG1598 COG1598, Uncharacterized conserved protein Function unknown 150391076 Common - peptidase M24 Amet_3338 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150390809 Nonpathogen - hypothetical protein Amet_3059 1 None None None 150388908 Common - protein of unknown function DUF541 Amet_1086 87 COG2968 COG2968, Uncharacterized conserved protein Function unknown 150390347 Common - single-strand binding protein Amet_2585 207 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150391288 Common - ABC transporter related Amet_3554 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150391379 Common - signal peptidase I Amet_3647 128 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150389275 Common - Cobyrinic acid a,c-diamide synthase Amet_1466 34 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150390117 Common - (p)ppGpp synthetase I, SpoT/RelA Amet_2353 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 150388639 Common - peptidase M22, glycoprotease Amet_0804 198 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 150390821 Common - Amidohydrolase 3 Amet_3071 113 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 150389768 Common - Spore coat protein CotH Amet_1995 34 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 150391756 Common - thioesterase superfamily protein Amet_4064 111 COG0824 FcbC, Predicted thioesterase General function prediction only 150390637 Common - Polypeptide-transport-associated protein domain protein, FtsQ-type Amet_2877 27 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 150390688 Nonpathogen - hypothetical protein Amet_2928 2 COG5660 COG5660, Predicted integral membrane protein Function unknown 150388130 Common - two component transcriptional regulator, winged helix family Amet_0288 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150392145 Common - ribosomal protein L6 Amet_4463 244 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 150390127 Common - membrane spanning protein Amet_2363 19 COG3610 COG3610, Uncharacterized conserved protein Function unknown 150391242 Common - transcriptional regulator, TetR family Amet_3505 42 COG1309 AcrR, Transcriptional regulator Transcription 150391947 Common - Rubrerythrin Amet_4259 12 COG1633 COG1633, Uncharacterized conserved protein Function unknown 150391178 Nonpathogen - hypothetical protein Amet_3440 1 None None None 150389743 Common - hypothetical protein Amet_1970 16 None None None 150390052 Common - electron transport complex, RnfABCDGE type, B subunit Amet_2285 145 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 150389340 Common - Abortive infection protein Amet_1544 11 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 150391803 Common - Pyridoxal-5'-phosphate-dependent protein, beta subunit Amet_4112 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150389086 Nonpathogen - hypothetical protein Amet_1270 1 COG4980 GvpP, Gas vesicle protein General function prediction only 150391401 Common - RNA methyltransferase, TrmA family Amet_3671 203 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 150391656 Common - hypothetical protein Amet_3958 33 COG4430 COG4430, Uncharacterized protein conserved in bacteria Function unknown 150388090 Common - CheC domain protein Amet_0247 20 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 150391233 Common - adenylylsulfate reductase Amet_3495 200 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150390038 Common - excinuclease ABC, C subunit, N-terminal protein Amet_2270 31 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 150390176 Common - phage portal protein Amet_2412 4 COG4695 COG4695, Phage-related protein Function unknown 150391507 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Amet_3778 71 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150392287 Nonpathogen - hypothetical protein Amet_4606 8 None None None 150389929 Common - GTP cyclohydrolase I Amet_2160 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 150389838 Common - N-acyl-D-amino-acid deacylase Amet_2067 103 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 150389374 Nonpathogen - hypothetical protein Amet_1585 1 None None None 150390937 Common - RnfA-Nqr electron transport subunit Amet_3189 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 150388768 Common - diguanylate cyclase and metal dependent phosphohydrolase Amet_0938 213 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150389919 Nonpathogen - hypothetical protein Amet_2150 11 None None None 150392009 Common - NADPH-dependent FMN reductase Amet_4325 38 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150388201 Common - transcriptional regulator, TetR family Amet_0361 29 COG1309 AcrR, Transcriptional regulator Transcription 150389016 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Amet_1198 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150390544 Common - protein of unknown function DUF116 Amet_2784 30 COG1852 COG1852, Uncharacterized conserved protein Function unknown 150388898 Common - protein of unknown function DUF6, transmembrane Amet_1076 145 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150388559 Common - flagellar protein Amet_0724 9 None None None 150391236 Nonpathogen - hypothetical protein Amet_3498 1 None None None 150389614 Common - permease Amet_1834 108 COG0701 COG0701, Predicted permeases General function prediction only 150388379 Common - 5'-Nucleotidase domain protein Amet_0542 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150391932 Common - citrate/H+ symporter, CitMHS family Amet_4244 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 150391266 Nonpathogen - hypothetical protein Amet_3530 1 None None None 150388034 Common - efflux transporter, RND family, MFP subunit Amet_0187 179 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150390753 Common - putative transcriptional regulator, GntR family Amet_2999 176 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150391854 Nonpathogen - hypothetical protein Amet_4163 9 None None None 150391908 Common - major facilitator superfamily MFS_1 Amet_4218 155 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150388355 Common - protein of unknown function DUF214 Amet_0518 27 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 150389504 Common - MATE efflux family protein Amet_1718 188 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150391006 Common - integral membrane sensor signal transduction histidine kinase Amet_3258 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150392330 Common - hypothetical protein Amet_4650 2 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 150391488 Common - methyl-accepting chemotaxis sensory transducer Amet_3759 150 COG4936 PocR, Predicted sensor domain Signal transduction mechanisms / Transcription 150388061 Common - protein of unknown function DUF1568 Amet_0216 48 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389992 Common - Sporulation protein YunB Amet_2224 14 None None None 150390353 Nonpathogen - hypothetical protein Amet_2591 1 None None None 150391896 Common - ABC transporter related Amet_4206 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150390297 Common - phage integrase family protein Amet_2534 204 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150392402 Common - phosphoesterase, PA-phosphatase related Amet_4724 20 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 150392448 Common - hypothetical protein Amet_4772 5 None None None 150390853 Common - HflC protein Amet_3103 200 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 150391395 Nonpathogen - hypothetical protein Amet_3663 1 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150390202 Common - cell wall hydrolase/autolysin Amet_2438 132 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150390961 Common - citrate/H+ symporter, CitMHS family Amet_3213 32 COG2851 CitM, H+/citrate symporter Energy production and conversion 150388070 Common - putative PAS/PAC sensor protein Amet_0225 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150392276 Nonpathogen - membrane protein Amet_4595 5 None None None 150392063 Nonpathogen - hypothetical protein Amet_4379 1 None None None 150388057 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_0212 14 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 150390896 Nonpathogen - hypothetical protein Amet_3147 1 None None None 150392309 Common - binding-protein-dependent transport systems inner membrane component Amet_4628 207 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 150390707 Common - glucose-1-phosphate adenylyltransferase, GlgD subunit Amet_2947 115 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 150389672 Common - Superoxide dismutase Amet_1897 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 150390792 Common - ribosomal protein S21 Amet_3042 108 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 150392393 Nonpathogen - hypothetical protein Amet_4715 3 COG4720 COG4720, Predicted membrane protein Function unknown 150388099 Common - ethanolamine ammonia-lyase small subunit Amet_0256 53 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 150388848 Common ribH riboflavin synthase subunit beta Amet_1021 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 150389058 Common - polar amino acid ABC transporter, inner membrane subunit Amet_1241 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150391939 Nonpathogen - hypothetical protein Amet_4251 1 None None None 150391930 Common - hypothetical protein Amet_4242 33 None None None 150387874 Common - phosphotransferase system, EIIC Amet_0021 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 150388012 Common - histone family protein DNA-binding protein Amet_0165 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 150392190 Common - transcriptional regulator, CarD family Amet_4508 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 150389786 Common - regulatory protein, ArsR Amet_2013 141 COG0640 ArsR, Predicted transcriptional regulators Transcription 150391014 Nonpathogen - hypothetical protein Amet_3266 1 None None None 150388283 Common - FAD linked oxidase domain protein Amet_0445 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150390223 Common - hypothetical protein Amet_2459 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 150390409 Common - transcriptional regulator, XRE family Amet_2647 108 COG1396 HipB, Predicted transcriptional regulators Transcription 150388873 Nonpathogen - hypothetical protein Amet_1048 1 None None None 150389679 Common - aminoglycoside phosphotransferase Amet_1905 13 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 150392384 Nonpathogen - Rhodanese domain protein Amet_4706 1 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150388369 Common - protein of unknown function DUF74 Amet_0532 82 COG0393 COG0393, Uncharacterized conserved protein Function unknown 150392218 Common - biotin/lipoyl attachment domain-containing protein Amet_4536 196 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 150388738 Common - aldo/keto reductase Amet_0907 155 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 150391728 Common - hypothetical protein Amet_4036 2 None None None 150390010 Nonpathogen - hypothetical protein Amet_2242 2 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 150388620 Common - flagellar hook-associated 2 domain protein Amet_0785 83 COG1345 FliD, Flagellar capping protein Cell motility and secretion 150390975 Common - response regulator receiver protein Amet_3227 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150392105 Common - putative transcriptional regulator, MerR family Amet_4423 73 COG0789 SoxR, Predicted transcriptional regulators Transcription 150388601 Common - Electron transfer flavoprotein, alpha subunit-like protein Amet_0766 172 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150391548 Common - protein of unknown function DUF1568 Amet_3821 53 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389616 Nonpathogen - hypothetical protein Amet_1836 1 None None None 150389831 Common - sigma54 specific transcriptional regulator, Fis family Amet_2060 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150388231 Common - transcriptional regulator/antitoxin, MazE Amet_0393 12 COG2336 MazE, Growth regulator Signal transduction mechanisms 150390538 Common - ribosome small subunit-dependent GTPase A Amet_2778 166 COG1162 COG1162, Predicted GTPases General function prediction only 150391388 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Amet_3656 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 150391732 Common - S-adenosylmethionine synthetase Amet_4040 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 150389699 Common - hypothetical protein Amet_1925 3 None None None 150389860 Common - nucleoside recognition domain protein Amet_2090 24 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 150389847 Common - ABC transporter related Amet_2077 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150390290 Common - pyrimidine-nucleoside phosphorylase Amet_2527 134 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 150390836 Common - multi-sensor signal transduction histidine kinase Amet_3086 225 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150390494 Common - response regulator receiver protein Amet_2733 218 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 150389828 Nonpathogen - hypothetical protein Amet_2057 1 None None None 150391371 Common - protein of unknown function DUF456 Amet_3639 17 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 150391573 Common - transcription activator, effector binding Amet_3846 130 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 150388126 Common - hypothetical protein Amet_0284 4 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 150389648 Nonpathogen - hypothetical protein Amet_1872 1 None None None 150390309 Nonpathogen - hypothetical protein Amet_2546 2 None None None 150388292 Common - glutamine amidotransferase class-I Amet_0454 151 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 150389092 Common - binding-protein-dependent transport systems inner membrane component Amet_1276 186 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150389631 Nonpathogen - hypothetical protein Amet_1852 1 None None None 150390046 Common - histidine kinase Amet_2279 30 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391619 Common - protein of unknown function DUF303, acetylesterase putative Amet_3913 12 None None None 150392422 Common - integral membrane sensor signal transduction histidine kinase Amet_4746 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150388198 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Amet_0358 212 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 150391339 Common - degV family protein Amet_3607 49 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150389116 Common - glycoside hydrolase, family 3 domain protein Amet_1301 183 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150388734 Common - Alanine racemase Amet_0902 131 COG1609 PurR, Transcriptional regulators Transcription 150391566 Common - hypothetical protein Amet_3839 6 None None None 150388007 Common - transcription-repair coupling factor Amet_0160 233 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 150392136 Common - translation initiation factor IF-1 Amet_4454 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 150390368 Common - hypothetical protein Amet_2606 99 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150390787 Common - protein of unknown function DUF1432 Amet_3037 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 150388037 Common - Spore coat protein CotH Amet_0190 9 None None None 150388065 Common - Mg chelatase, subunit ChlI Amet_0220 194 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 150390701 Common - amidohydrolase Amet_2941 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150392241 Common - hydroxylamine reductase Amet_4560 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150391424 Common - protein of unknown function DUF6, transmembrane Amet_3694 163 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150388771 Common - ATP-dependent DNA helicase PcrA Amet_0941 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150389562 Common - ketoreductase Amet_1780 86 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 150388565 Common - flagellar assembly protein FliW Amet_0730 42 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 150390226 Common - Holliday junction resolvase YqgF Amet_2462 182 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 150389403 Common - aspartate aminotransferase Amet_1616 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150391977 Common - Resolvase, N-terminal domain Amet_4291 46 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150388967 Nonpathogen - hypothetical protein Amet_1146 2 None None None 150391875 Common - YdjC family protein Amet_4184 46 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 150388541 Common - metal dependent phosphohydrolase Amet_0706 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150391885 Common - PTS system, lactose/cellobiose family IIC subunit Amet_4195 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150392075 Nonpathogen - hypothetical protein Amet_4391 1 None None None 150391793 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Amet_4102 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150389713 Nonpathogen - hypothetical protein Amet_1940 1 None None None 150389077 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Amet_1261 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 150390007 Nonpathogen - hypothetical protein Amet_2239 1 None None None 150390673 Common - binding-protein-dependent transport systems inner membrane component Amet_2913 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391677 Common - hypothetical protein Amet_3983 4 None None None 150390267 Common - exodeoxyribonuclease VII, small subunit Amet_2504 85 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 150389791 Common - Formiminotransferase-cyclodeaminase Amet_2019 37 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 150389802 Common - ferredoxin Amet_2030 66 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 150388167 Common - flavocytochrome c Amet_0327 190 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150392106 Common - arginase Amet_4424 146 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 150389042 Nonpathogen - Rubredoxin-type Fe(Cys)4 protein Amet_1224 10 COG1592 COG1592, Rubrerythrin Energy production and conversion 150391657 Nonpathogen - hypothetical protein Amet_3959 3 None None None 150391138 Common - acetolactate synthase, large subunit, biosynthetic type Amet_3400 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150392455 Common - recombination protein RecR Amet_4779 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 150390143 Common - hypothetical protein Amet_2379 4 None None None 150389176 Common - magnesium transporter Amet_1366 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 150392339 Common - hypothetical protein Amet_4659 3 None None None 150390762 Common - hypothetical protein Amet_3012 2 None None None 150389731 Common - hypothetical protein Amet_1958 2 None None None 150390641 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Amet_2881 212 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 150391919 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Amet_4229 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150390329 Common - phage-like element PBSX protein Amet_2567 4 None None None 150390063 Common - cell division topological specificity factor MinE Amet_2296 37 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 150390372 Nonpathogen - hypothetical protein Amet_2610 1 None None None 150391455 Common - Chloride channel, core Amet_3725 103 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 150388934 Common - protein of unknown function DUF1540 Amet_1113 2 None None None 150388978 Common - phosphonate metabolism protein PhnM Amet_1157 58 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 150392313 Common - protein of unknown function UPF0118 Amet_4632 168 COG0628 PerM, Predicted permease General function prediction only 150388287 Common - transposase, IS4 family protein Amet_0449 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150389413 Common - Methyltransferase type 11 Amet_1626 74 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150392073 Common - transcriptional regulator/antitoxin, MazE Amet_4389 12 COG2336 MazE, Growth regulator Signal transduction mechanisms 150392090 Common - multi-sensor signal transduction histidine kinase Amet_4407 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391358 Common - VanW family protein Amet_3626 39 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 150388214 Common - protein of unknown function DUF368 Amet_0374 49 COG2035 COG2035, Predicted membrane protein Function unknown 150391835 Common - putative transcriptional regulator, CopG family Amet_4144 14 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 150390313 Common - RNA-directed DNA polymerase (Reverse transcriptase) Amet_2550 82 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150389238 Nonpathogen - hypothetical protein Amet_1429 1 None None None 150389512 Common - Phosphate butyryltransferase Amet_1726 130 COG0280 Pta, Phosphotransacetylase Energy production and conversion 150388830 Common - DNA binding domain, excisionase family Amet_1003 21 None None None 150391609 Common - transcriptional repressor, CopY family Amet_3902 15 COG3682 COG3682, Predicted transcriptional regulator Transcription 150390921 Nonpathogen - hypothetical protein Amet_3172 1 None None None 150387918 Common - cobyrinic acid a,c-diamide synthase Amet_0065 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 150389663 Common - transposase, IS4 family protein Amet_1888 17 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 150392187 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Amet_4505 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 150389437 Common - aminotransferase, class V Amet_1650 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150389307 Nonpathogen - hypothetical protein Amet_1503 2 None None None 150388827 Common - formate dehydrogenase accessory protein Amet_1000 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 150389457 Common - Malate/lactate dehydrogenase-like protein Amet_1670 5 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 150390642 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Amet_2882 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 150387968 Common - transposase IS66 Amet_0117 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 150391985 Common - carbon starvation protein CstA Amet_4301 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 150388440 Common - response regulator receiver protein Amet_0603 223 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150390278 Common - regulatory protein RecX Amet_2515 53 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 150388505 Common - D-proline reductase (dithiol) Amet_0670 4 None None None 150390708 Common - glucose-1-phosphate adenylyltransferase Amet_2948 222 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 150389889 Common - Glutathione transferase Amet_2120 23 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150390952 Nonpathogen - hypothetical protein Amet_3204 1 None None None 150391841 Common - NADH dehydrogenase (quinone) Amet_4150 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 150389117 Common - glutamine synthetase, type I Amet_1302 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 150390690 Common - hypothetical protein Amet_2930 10 COG3874 COG3874, Uncharacterized conserved protein Function unknown 150388461 Nonpathogen - hypothetical protein Amet_0625 1 None None None 150392118 Nonpathogen - protein of unknown function DUF988 Amet_4436 3 COG4708 COG4708, Predicted membrane protein Function unknown 150389425 Common - RNA methyltransferase, TrmH family, group 3 Amet_1638 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150388344 Common - glycyl-radical enzyme activating protein family Amet_0507 80 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150390379 Nonpathogen - hypothetical protein Amet_2617 1 None None None 150392359 Nonpathogen - hypothetical protein Amet_4681 2 None None None 150390875 Common - hypothetical protein Amet_3126 30 None None None 150390447 Nonpathogen - hypothetical protein Amet_2685 1 None None None 150389211 Nonpathogen - hypothetical protein Amet_1401 1 None None None 150392167 Common - DNA-directed RNA polymerase subunit beta' Amet_4485 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 150391406 Nonpathogen - hypothetical protein Amet_3676 1 None None None 150390436 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Amet_2674 23 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 150392165 Common rpsL 30S ribosomal protein S12 Amet_4483 244 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 150390335 Nonpathogen - hypothetical protein Amet_2573 2 None None None 150389684 Common - transposase Amet_1910 6 None None None 150390993 Common - Dynamin family protein Amet_3245 68 COG1159 Era, GTPase General function prediction only 150389204 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Amet_1394 58 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150392269 Common - transcriptional regulator, CdaR Amet_4588 49 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 150391315 Common - inner-membrane translocator Amet_3583 118 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 150392476 Common - protein of unknown function DUF37 Amet_4800 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 150391855 Common - ABC transporter related Amet_4164 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150387921 Common - GHMP kinase Amet_0068 18 COG4542 PduX, Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase Secondary metabolites biosynthesis, transport, and catabolism 150388860 Common - secretion protein HlyD family protein Amet_1033 109 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150389435 Common - Orn/DAP/Arg decarboxylase 2 Amet_1648 115 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 150389751 Common - phage integrase domain protein SAM domain protein Amet_1978 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150388426 Common - ABC-type sugar transport system periplasmic component-like protein Amet_0589 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150390028 Nonpathogen - hypothetical protein Amet_2260 1 None None None 150388154 Common - transcriptional regulator, TetR family Amet_0314 143 COG1309 AcrR, Transcriptional regulator Transcription 150390669 Common - extracellular solute-binding protein, family 5 Amet_2909 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150390919 Common - ATP-dependent metalloprotease FtsH Amet_3170 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150388999 Common - protein of unknown function DUF156 Amet_1181 107 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 150389750 Nonpathogen - hypothetical protein Amet_1977 1 None None None 150390008 Common - aminoglycoside nucleotidyltransferase, putative Amet_2240 7 None None None 150390488 Common - flagellar hook-basal body complex subunit FliE Amet_2726 67 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 150388478 Common - TRAP transporter solute receptor, TAXI family Amet_0643 83 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 150391147 Common - citrate lyase, alpha subunit Amet_3409 28 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 150391137 Common - hypothetical protein Amet_3399 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 150391961 Common - hypothetical protein Amet_4273 2 None None None 150387895 Common - amidohydrolase Amet_0042 130 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150391102 Common - transcriptional regulator/antitoxin, MazE Amet_3364 15 COG2336 MazE, Growth regulator Signal transduction mechanisms 150388617 Nonpathogen - hypothetical protein Amet_0782 7 None None None 150389355 Common - beta-lactamase Amet_1561 97 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150391962 Common - tartrate dehydrogenase Amet_4274 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 150390103 Common ruvB Holliday junction DNA helicase B Amet_2339 235 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 150390101 Common - crossover junction endodeoxyribonuclease RuvC Amet_2337 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 150390763 Common - 30S ribosomal protein S4 Amet_3013 242 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 150391821 Common - protein of unknown function DUF214 Amet_4130 125 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 150391819 Common - carboxyl-terminal protease Amet_4128 190 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150389348 Common - protein of unknown function DUF214 Amet_1554 180 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150391248 Common - protein of unknown function DUF112, transmembrane Amet_3511 76 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 150389518 Common - metallophosphoesterase Amet_1732 103 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150390667 Common - binding-protein-dependent transport systems inner membrane component Amet_2907 222 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390767 Nonpathogen - hypothetical protein Amet_3017 1 COG4817 COG4817, Uncharacterized protein conserved in bacteria Function unknown 150392230 Common - cobalamin B12-binding domain protein Amet_4548 22 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 150388517 Common - (2Fe-2S)-binding domain protein Amet_0682 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 150389008 Common - hypothetical protein Amet_1190 10 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150389520 Common - binding-protein-dependent transport systems inner membrane component Amet_1734 169 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150389547 Common - Integrase, catalytic region Amet_1765 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150391472 Common - N-formylglutamate amidohydrolase Amet_3743 44 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 150392153 Common rplP 50S ribosomal protein L16 Amet_4471 219 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 150388647 Common - transcriptional regulator, MarR family Amet_0812 4 COG1846 MarR, Transcriptional regulators Transcription 150392213 Common - Citrate transporter Amet_4531 41 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 150388629 Common - flagellar biosynthesis protein Amet_0794 96 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 150390239 Common - Resolvase, N-terminal domain Amet_2475 136 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150390819 Common - ABC-2 type transporter Amet_3069 143 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150391717 Common - phage head-tail adaptor, putative Amet_4025 5 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 150388606 Common - metal dependent phosphohydrolase Amet_0771 62 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 150389456 Common - NADPH-dependent FMN reductase Amet_1669 2 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150389482 Nonpathogen - Domain of unknown function DUF1874 Amet_1696 3 None None None 150389627 Nonpathogen - hypothetical protein Amet_1847 2 None None None 150389389 Common - Resolvase, N-terminal domain Amet_1602 31 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150391433 Common - hypothetical protein Amet_3703 11 None None None 150389702 Nonpathogen - hypothetical protein Amet_1929 1 None None None 150388354 Common - phosphonate ABC transporter, inner membrane subunit Amet_0517 122 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 150388529 Common - Na+/H+ antiporter NhaC Amet_0694 73 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 150392089 Common - protein of unknown function DUF21 Amet_4406 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150388333 Common - S-layer domain protein Amet_0496 23 None None None 150391785 Common - extracellular solute-binding protein, family 1 Amet_4094 70 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150389576 Nonpathogen - hypothetical protein Amet_1796 1 None None None 150387932 Nonpathogen - hypothetical protein Amet_0079 1 None None None 150390212 Common - hypothetical protein Amet_2448 4 None None None 150389404 Common - polysaccharide deacetylase Amet_1617 131 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150391394 Common - NLP/P60 protein Amet_3662 134 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150389640 Common - beta-lactamase domain protein Amet_1861 37 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150390460 Common - CheA signal transduction histidine kinase Amet_2698 163 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 150389943 Common - Radical SAM domain protein Amet_2174 89 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150392430 Nonpathogen - hypothetical protein Amet_4754 5 COG4853 COG4853, Uncharacterized protein conserved in bacteria Function unknown 150391364 Nonpathogen - hypothetical protein Amet_3632 1 None None None 150388166 Common - putative transcriptional regulator, MerR family Amet_0326 84 COG0789 SoxR, Predicted transcriptional regulators Transcription 150391300 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_3568 70 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150389986 Nonpathogen - hypothetical protein Amet_2218 1 None None None 150390352 Nonpathogen - hypothetical protein Amet_2590 1 None None None 150391096 Common - hypothetical protein Amet_3358 25 None None None 150391707 Common - N-acetylmuramoyl-L-alanine amidase, family 2 Amet_4015 9 COG5632 COG5632, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150389941 Common - diguanylate cyclase with PAS/PAC sensor Amet_2172 188 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150391118 Common - acetylornithine and succinylornithine aminotransferase Amet_3380 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150388273 Common - hypothetical protein Amet_0435 3 None None None 150388857 Common - Stage II sporulation E family protein Amet_1030 110 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150389865 Nonpathogen - hypothetical protein Amet_2095 6 None None None 150389872 Nonpathogen - hypothetical protein Amet_2102 1 None None None 150392292 Common - SpoIID/LytB domain protein Amet_4611 176 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150390471 Common - response regulator receiver protein Amet_2709 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150391687 Nonpathogen - hypothetical protein Amet_3995 1 None None None 150390032 Common - hypothetical protein Amet_2264 2 None None None 150388138 Common - MotA/TolQ/ExbB proton channel Amet_0296 117 COG1291 MotA, Flagellar motor component Cell motility and secretion 150389322 Common - integral membrane sensor signal transduction histidine kinase Amet_1519 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390520 Common - fatty acid/phospholipid synthesis protein PlsX Amet_2759 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 150388336 Common - hypothetical protein Amet_0499 11 None None None 150389728 Common - hypothetical protein Amet_1955 14 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 150390517 Common - malonyl CoA-acyl carrier protein transacylase Amet_2756 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 150389269 Common - protein of unknown function DUF214 Amet_1460 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150391661 Nonpathogen - hypothetical protein Amet_3964 1 None None None 150391910 Common - DEAD_2 domain protein Amet_4220 112 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 150387939 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Amet_0086 47 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150391338 Common - tyrosyl-tRNA synthetase Amet_3606 218 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150389707 Nonpathogen - hypothetical protein Amet_1934 1 None None None 150391700 Common - hypothetical protein Amet_4008 6 None None None 150388766 Nonpathogen - hypothetical protein Amet_0936 1 None None None 150391297 Nonpathogen - hypothetical protein Amet_3565 2 None None None 150390302 Common - GTP-binding protein, HSR1-related Amet_2539 6 COG2262 HflX, GTPases General function prediction only 150390118 Common - D-tyrosyl-tRNA(Tyr) deacylase Amet_2354 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 150389243 Common - protein of unknown function DUF1697 Amet_1434 24 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 150389874 Common - putative transcriptional regulator, XRE family Amet_2104 49 COG3655 COG3655, Predicted transcriptional regulator Transcription 150391032 Common - Rhodanese domain protein Amet_3291 33 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150390926 Common - transposase Amet_3178 6 None None None 150392247 Common - hypothetical protein Amet_4566 18 None None None 150388828 Common - polynucleotide phosphorylase/polyadenylase Amet_1001 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 150392350 Common - ABC transporter related Amet_4670 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150389336 Common - ABC transporter ATP-binding protein Amet_1536 200 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150388979 Common - ABC transporter related Amet_1158 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 150388542 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Amet_0707 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150388538 Common - Indigoidine synthase A family protein Amet_0703 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 150389185 Common - Glucose-6-phosphate isomerase Amet_1375 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 150392252 Common - molybdopterin dehydrogenase, FAD-binding Amet_4571 101 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 150389429 Common - peptidase U32 Amet_1642 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150388850 Common - binding-protein-dependent transport systems inner membrane component Amet_1023 200 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 150391015 Common - Methyltransferase type 11 Amet_3267 148 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150390886 Common - cation diffusion facilitator family transporter Amet_3137 195 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150389226 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1416 125 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150391073 Common - PP-loop domain protein Amet_3335 163 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 150388915 Nonpathogen - hypothetical protein Amet_1093 1 None None None 150388088 Nonpathogen - hypothetical protein Amet_0245 5 None None None 150388881 Common - Peptidase M16C associated domain protein Amet_1059 95 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 150390604 Nonpathogen - hypothetical protein Amet_2844 1 None None None 150390868 Nonpathogen - hypothetical protein Amet_3119 1 None None None 150389900 Common - GCN5-related N-acetyltransferase Amet_2131 28 COG3153 COG3153, Predicted acetyltransferase General function prediction only 150391538 Nonpathogen - hypothetical protein Amet_3810 1 None None None 150389295 Nonpathogen - copper amine oxidase domain protein Amet_1489 10 None None None 150389240 Common - beta-lactamase Amet_1431 106 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150389443 Common - Excinuclease ABC, C subunit domain protein Amet_1656 81 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 150388179 Common - uracil phosphoribosyltransferase Amet_0339 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 150391699 Common - Resolvase, N-terminal domain Amet_4007 107 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150389603 Nonpathogen - hypothetical protein Amet_1823 1 None None None 150392091 Common - ErfK/YbiS/YcfS/YnhG family protein Amet_4408 71 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150388659 Common - hypothetical protein Amet_0824 14 None None None 150389551 Common - DNA-directed DNA polymerase Amet_1769 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 150388084 Common - hypothetical protein Amet_0241 3 None None None 150387902 Common - putative transcriptional regulator, AsnC family Amet_0049 52 COG1522 Lrp, Transcriptional regulators Transcription 150390600 Nonpathogen - hypothetical protein Amet_2840 2 None None None 150388580 Nonpathogen - hypothetical protein Amet_0745 1 None None None 150388786 Common - ribonuclease PH Amet_0956 208 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 150390453 Nonpathogen - hypothetical protein Amet_2691 1 None None None 150388263 Nonpathogen - hypothetical protein Amet_0425 1 None None None 150390732 Common - urea amidolyase related protein Amet_2973 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 150391527 Common - ABC transporter related Amet_3798 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150388804 Common - fructose-1,6-bisphosphatase Amet_0977 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 150391517 Common - TRAP dicarboxylate transporter- DctP subunit Amet_3788 117 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150388680 Nonpathogen - hypothetical protein Amet_0845 1 None None None 150389303 Common - transposase, IS4 family protein Amet_1499 65 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389780 Common - extracellular solute-binding protein, family 5 Amet_2007 202 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150389638 Nonpathogen - hypothetical protein Amet_1859 1 None None None 150389909 Nonpathogen - hypothetical protein Amet_2140 2 None None None 150391729 Common - hypothetical protein Amet_4037 8 None None None 150388838 Nonpathogen - hypothetical protein Amet_1011 1 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150390196 Nonpathogen - hypothetical protein Amet_2432 1 None None None 150388942 Common - ABC transporter related Amet_1121 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150388015 Common - SpoIID/LytB domain protein Amet_0168 45 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 150389911 Common - ADP-ribosylglycohydrolase Amet_2142 6 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 150390774 Common - DNA repair protein RecO Amet_3024 105 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 150391867 Common - ATP-dependent nuclease subunit AddB Amet_4176 28 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 150388291 Common - VanZ family protein Amet_0453 14 COG5652 COG5652, Predicted integral membrane protein Function unknown 150387959 Nonpathogen - hypothetical protein Amet_0107 1 None None None 150390425 Common - peptidase S14, ClpP Amet_2663 24 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150392082 Nonpathogen - hypothetical protein Amet_4399 1 None None None 150392131 Common - DNA-directed RNA polymerase, alpha subunit Amet_4449 221 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 150389063 Common - thiamine-phosphate pyrophosphorylase Amet_1247 185 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 150390041 Nonpathogen - Sporulation domain protein Amet_2274 1 None None None 150390940 Nonpathogen - hypothetical protein Amet_3192 1 None None None 150388143 Common - hypothetical protein Amet_0301 10 None None None 150389375 Common - conserved hypothetical protein 245 Amet_1586 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 150388748 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Amet_0918 196 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 150392306 Common - beta-lactamase domain protein Amet_4625 108 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150391672 Nonpathogen - hypothetical protein Amet_3977 1 None None None 150391620 Common - hypothetical protein Amet_3914 36 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 150389961 Common - CRISPR-associated protein Cas5 family Amet_2192 5 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 150391955 Common - Alcohol dehydrogenase, zinc-binding domain protein Amet_4267 96 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150389468 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_1681 165 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150391912 Nonpathogen - hypothetical protein Amet_4222 1 None None None 150389108 Common - Mannitol dehydrogenase, C-terminal domain Amet_1293 74 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150388243 Nonpathogen - hypothetical protein Amet_0405 1 None None None 150391551 Common - acetaldehyde dehydrogenase (acetylating) Amet_3824 167 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150388480 Nonpathogen - hypothetical protein Amet_0645 1 None None None 150390976 Common - integral membrane sensor signal transduction histidine kinase Amet_3228 210 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150390386 Common - RNA binding S1 domain protein Amet_2624 219 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 150388693 Nonpathogen - hypothetical protein Amet_0858 1 None None None 150389774 Common - hypothetical protein Amet_2001 3 None None None 150390132 Common - hypothetical protein Amet_2368 7 None None None 150391469 Common - protein of unknown function DUF6, transmembrane Amet_3740 199 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150391124 Common - glutamine synthetase, type I Amet_3386 230 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 150391812 Common - putative glucokinase, ROK family Amet_4121 163 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150391907 Common asnC asparaginyl-tRNA synthetase Amet_4217 231 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150392437 Common - peptidase M23B Amet_4761 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150391413 Common - major facilitator superfamily MFS_1 Amet_3683 95 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150388450 Common - response regulator receiver protein Amet_0614 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150391589 Nonpathogen - hypothetical protein Amet_3866 1 None None None 150390016 Nonpathogen - hypothetical protein Amet_2248 2 None None None 150391751 Nonpathogen - hypothetical protein Amet_4059 1 None None None 150388471 Common - hypothetical protein Amet_0636 5 None None None 150388464 Nonpathogen - hypothetical protein Amet_0628 1 None None None 150391828 Nonpathogen - hypothetical protein Amet_4137 1 None None None 150389511 Common - TPR repeat-containing protein Amet_1725 62 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 150390186 Nonpathogen - hypothetical protein Amet_2422 1 None None None 150392050 Common - phage uncharacterized protein Amet_4366 23 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 150388277 Nonpathogen - hypothetical protein Amet_0439 1 None None None 150390338 Nonpathogen - hypothetical protein Amet_2576 2 None None None 150389103 Common - TRAP dicarboxylate transporter, DctP subunit Amet_1288 103 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150389935 Common - small acid-soluble spore H family protein Amet_2166 4 None None None 150391066 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_3328 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391164 Common - Mur ligase, middle domain protein Amet_3426 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 150389582 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_1802 147 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150389587 Nonpathogen - hypothetical protein Amet_1807 1 None None None 150390162 Common - hypothetical protein Amet_2398 6 None None None 150387883 Common - protein of unknown function DUF951 Amet_0030 26 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 150388105 Common - Propanediol utilization protein Amet_0262 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 150388280 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Amet_0442 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150389975 Common - molybdenum cofactor biosynthesis protein C Amet_2207 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 150392057 Common - hypothetical protein Amet_4373 3 COG5566 COG5566, Uncharacterized conserved protein Function unknown 150389272 Common - protein of unknown function DUF134 Amet_1463 41 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 150390530 Common - small acid-soluble spore protein, alpha/beta type Amet_2769 14 None None None 150388225 Common - hypothetical protein Amet_0387 3 None None None 150388794 Common - diguanylate cyclase and metal dependent phosphohydrolase Amet_0967 202 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150392224 Common - methylmalonyl-CoA mutase, large subunit Amet_4542 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 150388489 Common - NLP/P60 protein Amet_0654 35 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150388454 Common - two component transcriptional regulator, LytTR family Amet_0618 143 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150389120 Common - Radical SAM domain protein Amet_1305 65 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150388673 Common - helix-turn-helix domain protein Amet_0838 6 COG4800 COG4800, Predicted transcriptional regulator with an HTH domain Transcription 150389338 Common - YbaK/prolyl-tRNA synthetase associated region Amet_1540 76 COG2606 EbsC, Uncharacterized conserved protein Function unknown 150389956 Common - Helix-turn-helix, type 11 domain protein Amet_2187 66 COG2378 COG2378, Predicted transcriptional regulator Transcription 150390956 Common - integral membrane sensor signal transduction histidine kinase Amet_3208 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150392427 Common - 2-alkenal reductase Amet_4751 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 150391153 Common - methylaspartate mutase, E subunit Amet_3415 17 COG4865 COG4865, Glutamate mutase epsilon subunit Amino acid transport and metabolism 150389151 Common - efflux transporter, RND family, MFP subunit Amet_1340 167 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150389364 Common - methyl-accepting chemotaxis sensory transducer Amet_1575 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150391351 Common - periplasmic binding protein Amet_3619 176 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150391923 Common - thiamine biosynthesis protein ThiC Amet_4233 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 150388983 Common - transposase Amet_1163 6 None None None 150390828 Common - protein of unknown function DUF214 Amet_3078 62 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150392002 Nonpathogen - Ion transport 2 domain protein Amet_4318 4 None None None 150389572 Common - transposase and inactivated derivatives Amet_1791 16 None None None 150390812 Common - beta-lactamase domain protein Amet_3062 125 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 150391201 Nonpathogen - hypothetical protein Amet_3463 1 None None None 150390075 Common - protein of unknown function UPF0044 Amet_2308 90 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 150388202 Common - efflux transporter, RND family, MFP subunit Amet_0362 176 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150389098 Common - spore germination protein Amet_1283 15 None None None 150389620 Common - permease Amet_1840 51 COG0701 COG0701, Predicted permeases General function prediction only 150387990 Common - Rhodanese domain protein Amet_0141 102 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150389147 Common - hypothetical protein Amet_1335 79 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 150389331 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_1529 24 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 150388911 Common - glycoside hydrolase, family 18 Amet_1089 31 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 150389491 Common - metal dependent phosphohydrolase Amet_1705 125 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150390784 Common - putative stage IV sporulation YqfD Amet_3034 15 None None None 150391463 Nonpathogen - hypothetical protein Amet_3734 1 None None None 150392342 Nonpathogen - hypothetical protein Amet_4662 1 None None None 150388098 Common - Ethanolamine ammonia lyase large subunit Amet_0255 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 150390037 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Amet_2269 24 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 150388888 Common - trigger factor Amet_1066 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 150389719 Common - hypothetical protein Amet_1946 3 COG5566 COG5566, Uncharacterized conserved protein Function unknown 150391179 Common - hypothetical protein Amet_3441 17 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150392142 Common - ribosomal protein L30 Amet_4460 149 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 150388310 Nonpathogen - hypothetical protein Amet_0473 1 None None None 150390051 Common - electron transport complex, RnfABCDGE type, A subunit Amet_2284 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 150391111 Common - homocysteine S-methyltransferase Amet_3373 180 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150389161 Common - hypothetical protein Amet_1351 4 None None None 150389251 Common - phospholipid/glycerol acyltransferase Amet_1442 127 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150390144 Nonpathogen - hypothetical protein Amet_2380 1 None None None 150390327 Nonpathogen - hypothetical protein Amet_2565 1 None None None 150388716 Nonpathogen - hypothetical protein Amet_0884 1 None None None 150390171 Common - phage integrase family protein Amet_2407 104 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150388488 Common - Argininosuccinate synthase Amet_0653 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 150390820 Common - ABC transporter related Amet_3070 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150390225 Common - aldo/keto reductase Amet_2461 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 150389560 Nonpathogen - hypothetical protein Amet_1778 2 None None None 150390320 Common - hypothetical protein Amet_2558 3 None None None 150391075 Nonpathogen - hypothetical protein Amet_3337 2 None None None 150390474 Common - flagellar basal body-associated protein FliL Amet_2712 14 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 150392370 Nonpathogen - hypothetical protein Amet_4692 1 None None None 150387859 Common - DNA gyrase, B subunit Amet_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 150390418 Common - Stage V sporulation protein S Amet_2656 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 150387975 Common - transposase Amet_0126 8 None None None 150389836 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_2065 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 150389647 Nonpathogen - hypothetical protein Amet_1871 1 None None None 150389209 Nonpathogen - hypothetical protein Amet_1399 2 None None None 150389262 Common - ThiJ/PfpI domain protein Amet_1453 106 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150389910 Nonpathogen - hypothetical protein Amet_2141 1 None None None 150391681 Common - hypothetical protein Amet_3988 14 None None None 150388328 Nonpathogen - hypothetical protein Amet_0491 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 150389907 Nonpathogen - hypothetical protein Amet_2138 2 None None None 150390485 Common - Flagellar biosynthesis/type III secretory pathway protein-like protein Amet_2723 30 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 150390586 Common - nitroreductase Amet_2826 10 COG0778 NfnB, Nitroreductase Energy production and conversion 150388490 Common - integral membrane sensor signal transduction histidine kinase Amet_0655 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150389771 Common - leucine-rich repeat-containing protein, typical subtype Amet_1998 39 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 150391303 Common - TrkA-C domain protein Amet_3571 7 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 150391581 Common - protein of unknown function UPF0016 Amet_3856 71 COG2119 COG2119, Predicted membrane protein Function unknown 150391378 Common - gamma-glutamyl phosphate reductase Amet_3646 193 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 150388190 Common - ATP synthase F1, delta subunit Amet_0350 191 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 150390130 Common - sigma54 specific transcriptional regulator, Fis family Amet_2366 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150389790 Common - Formate--tetrahydrofolate ligase Amet_2018 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 150388759 Common - methyl-accepting chemotaxis sensory transducer Amet_0929 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150390573 Common - ABC transporter related Amet_2813 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150391946 Common - aspartate racemase Amet_4258 72 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 150388304 Nonpathogen - hypothetical protein Amet_0466 5 None None None 150392154 Common - ribosomal protein S3 Amet_4472 238 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 150392286 Common - Peptidoglycan-binding LysM Amet_4605 8 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 150390566 Nonpathogen - hypothetical protein Amet_2806 1 None None None 150389767 Common - hypothetical protein Amet_1994 11 None None None 150388532 Common - 4-aminobutyrate aminotransferase Amet_0697 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 150389483 Common - flavodoxin/nitric oxide synthase Amet_1697 82 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150391624 Common - transposase, IS4 family protein Amet_3919 17 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 150391755 Common - FxsA cytoplasmic membrane protein Amet_4063 73 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 150391272 Common - histidine kinase Amet_3536 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150391359 Common - cell division protein FtsA Amet_3627 161 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 150390726 Common - response regulator receiver and unknown domain protein Amet_2966 224 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 150392156 Common rpsS 30S ribosomal protein S19 Amet_4474 240 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 150387957 Nonpathogen - hypothetical protein Amet_0104 1 None None None 150390070 Common - ribosomal protein L21 Amet_2303 186 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 150388638 Common - protein of unknown function UPF0079 Amet_0803 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 150391633 Nonpathogen - hypothetical protein Amet_3930 1 None None None 150389928 Common - aminotransferase, class IV Amet_2159 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150391765 Common - glutamate formiminotransferase Amet_4073 22 COG3643 COG3643, Glutamate formiminotransferase Amino acid transport and metabolism 150391241 Common - ybaK/ebsC protein Amet_3503 109 COG2606 EbsC, Uncharacterized conserved protein Function unknown 150389742 Common - hypothetical protein Amet_1969 2 None None None 150391993 Common - phosphate butyryltransferase Amet_4309 132 COG0280 Pta, Phosphotransacetylase Energy production and conversion 150389837 Common - NLP/P60 protein Amet_2066 143 COG2367 PenP, Beta-lactamase class A Defense mechanisms 150391800 Common - ferredoxin Amet_4109 21 COG3411 COG3411, Ferredoxin Energy production and conversion 150389276 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Amet_1467 32 COG1433 COG1433, Uncharacterized conserved protein Function unknown 150388977 Common - ABC transporter related Amet_1156 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 150391324 Common - glycine/sarcosine/betaine reductase complex protein A Amet_3592 7 None None None 150389047 Common - regulatory protein, ArsR Amet_1229 177 COG0640 ArsR, Predicted transcriptional regulators Transcription 150388036 Common - transcriptional regulator, TetR family Amet_0189 98 COG1309 AcrR, Transcriptional regulator Transcription 150390743 Common - ribonuclease H Amet_2989 42 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 150389230 Common - GCN5-related N-acetyltransferase Amet_1420 15 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150390371 Nonpathogen - hypothetical protein Amet_2609 1 None None None 150389568 Common - hypothetical protein Amet_1787 2 None None None 150388661 Common - 1-phosphofructokinase Amet_0826 99 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 150391257 Common - nitrogenase molybdenum-iron protein beta chain Amet_3520 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150388217 Common - addiction module toxin, RelE/StbE family Amet_0378 12 COG3668 ParE, Plasmid stabilization system protein General function prediction only 150392457 Common - DNA polymerase III subunits gamma and tau Amet_4781 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 150390911 Common - histidinol phosphate phosphatase HisJ family Amet_3162 40 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 150388592 Common - nucleoside recognition domain protein Amet_0757 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 150390285 Common - Sporulation stage II, protein M Amet_2522 14 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 150391731 Common - DNA methylase N-4/N-6 domain protein Amet_4039 78 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 150390201 Common - toxin secretion/phage lysis holin Amet_2437 13 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 150391480 Common - L-lactate transport Amet_3751 104 COG1620 LldP, L-lactate permease Energy production and conversion 150391130 Common - ammonium transporter Amet_3392 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 150387981 Common - regulatory protein GntR, HTH Amet_0132 96 COG1725 COG1725, Predicted transcriptional regulators Transcription 150391895 Common - ABC-2 type transporter Amet_4205 27 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 150392352 Common - DNA mismatch repair protein MutS domain protein Amet_4672 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150392447 Common - membrane protein-like protein Amet_4771 5 COG4241 COG4241, Predicted membrane protein Function unknown 150391082 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Amet_3344 116 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150392468 Common - Cobyrinic acid a,c-diamide synthase Amet_4792 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150388436 Common - protein of unknown function DUF214 Amet_0599 71 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150390380 Common - aspartate aminotransferase Amet_2618 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150390599 Nonpathogen - hypothetical protein Amet_2839 1 None None None 150390687 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_2927 160 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150391400 Nonpathogen - hypothetical protein Amet_3670 1 None None None 150392310 Common - extracellular solute-binding protein, family 1 Amet_4629 110 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 150389462 Common - ABC transporter related Amet_1675 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150392064 Nonpathogen - hypothetical protein Amet_4380 1 None None None 150390954 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Amet_3206 132 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 150388905 Common trpA tryptophan synthase subunit alpha Amet_1083 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 150388144 Common - UDP-glucose 4-epimerase Amet_0302 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 150392328 Common - transketolase Amet_4648 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 150392191 Common - hypothetical protein Amet_4509 9 None None None 150391439 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Amet_3709 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 150387961 Nonpathogen - hypothetical protein Amet_0109 1 None None None 150391024 Nonpathogen - hypothetical protein Amet_3277 2 None None None 150389284 Nonpathogen - hypothetical protein Amet_1477 1 None None None 150390057 Common - cell shape determining protein, MreB/Mrl family Amet_2290 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 150388924 Nonpathogen - hypothetical protein Amet_1103 2 None None None 150390612 Common - phage related protein Amet_2852 2 None None None 150388371 Common - hypothetical protein Amet_0534 10 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 150392440 Common - DNA replication protein DnaC Amet_4764 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150388574 Common - nucleotidyltransferase substrate binding protein, HI0074 family Amet_0739 32 None None None 150390801 Common - putative oxygen-independent coproporphyrinogen III oxidase Amet_3051 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150388728 Common - extracellular solute-binding protein, family 1 Amet_0896 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150389123 Nonpathogen - hypothetical protein Amet_1309 1 None None None 150388810 Common - protein tyrosine phosphatase Amet_0983 128 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 150390747 Common - RNA polymerase, sigma 70 subunit, RpoD family Amet_2993 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 150392104 Common - hypothetical protein Amet_4422 23 COG3461 COG3461, Uncharacterized conserved protein Function unknown 150391331 Nonpathogen - hypothetical protein Amet_3599 1 None None None 150391225 Common - Radical SAM domain protein Amet_3487 77 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150391340 Common - protein of unknown function DUF362 Amet_3608 14 COG2006 COG2006, Uncharacterized conserved protein Function unknown 150389270 Common - alkyl hydroperoxide reductase Amet_1461 191 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150390139 Common - hypothetical protein Amet_2375 6 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 150390429 Common - polynucleotide phosphorylase/polyadenylase Amet_2667 241 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 150388326 Common - two component transcriptional regulator, LuxR family Amet_0489 191 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150391519 Common - zinc finger, SWIM-type Amet_3790 39 COG4279 COG4279, Uncharacterized conserved protein Function unknown 150391380 Common - hypothetical protein Amet_3648 5 None None None 150391489 Common - putative CheW protein Amet_3760 104 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150389854 Common - transcriptional regulator, TetR family Amet_2084 43 COG1309 AcrR, Transcriptional regulator Transcription 150391658 Nonpathogen - hypothetical protein Amet_3960 2 None None None 150388146 Common - transposase, IS4 family protein Amet_0304 19 None None None 150391218 Common - type II secretion system protein Amet_3480 149 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 150390367 Nonpathogen - hypothetical protein Amet_2605 1 None None None 150388770 Common - methyl-accepting chemotaxis sensory transducer Amet_0940 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150391533 Common - signal transduction histidine kinase, LytS Amet_3805 121 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150392098 Common trkA potassium transporter peripheral membrane component Amet_4416 182 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 150391888 Common - phosphatidylserine decarboxylase Amet_4198 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 150390795 Common - protein of unknown function DUF558 Amet_3045 202 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 150388483 Common - Prephenate dehydratase Amet_0648 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 150390018 Nonpathogen - hypothetical protein Amet_2250 2 None None None 150390259 Common - Sporulation stage III, protein AE Amet_2496 15 None None None 150390270 Common - hypothetical protein Amet_2507 12 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150390096 Common - tRNA pseudouridine synthase A Amet_2332 230 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 150390395 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Amet_2633 115 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150391425 Common - flavodoxin Amet_3695 26 COG0716 FldA, Flavodoxins Energy production and conversion 150388615 Common - Domain of unknown function DUF1850 Amet_0780 3 COG4729 COG4729, Uncharacterized conserved protein Function unknown 150392240 Nonpathogen - hypothetical protein Amet_4559 1 None None None 150391500 Common - ABC transporter related Amet_3771 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150391742 Common - hypothetical protein Amet_4050 12 None None None 150392266 Common - Formate--tetrahydrofolate ligase Amet_4585 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 150390700 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Amet_2940 84 COG0546 Gph, Predicted phosphatases General function prediction only 150391618 Common - transcriptional regulator, PadR-like family Amet_3912 6 COG1695 COG1695, Predicted transcriptional regulators Transcription 150388400 Common - MgtC/SapB transporter Amet_0563 120 COG1285 SapB, Uncharacterized membrane protein Function unknown 150389621 Common - regulatory protein, ArsR Amet_1841 138 COG0640 ArsR, Predicted transcriptional regulators Transcription 150389202 Common - cyclic nucleotide-binding protein Amet_1392 27 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150389799 Common - dihydropteroate synthase, DHPS Amet_2027 155 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150390439 Common - protein of unknown function DUF150 Amet_2677 180 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 150391370 Common - endodeoxyribonuclease RusA Amet_3638 3 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 150388157 Common - acyl-CoA hydrolase Amet_0317 19 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 150390974 Common - Citrate carrier protein Amet_3226 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 150389848 Common - ABC transporter related Amet_2078 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150390900 Common - transcriptional regulator, MarR family Amet_3151 119 COG1846 MarR, Transcriptional regulators Transcription 150388551 Common - Methionine adenosyltransferase Amet_0716 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 150388566 Common - carbon storage regulator, CsrA Amet_0731 83 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 150391547 Common - transposase, IS4 family protein Amet_3819 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 150392456 Common - conserved hypothetical protein 103 Amet_4780 178 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 150389438 Common - ABC-type Co2+ transport system permease component-like protein Amet_1651 41 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 150391814 Common - phage shock protein C, PspC Amet_4123 41 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 150388286 Nonpathogen - hypothetical protein Amet_0448 1 None None None 150390350 Nonpathogen - hypothetical protein Amet_2588 1 None None None 150392074 Common - hypothetical protein Amet_4390 2 None None None 150392129 Common - ABC transporter related Amet_4447 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150388500 Common - D-proline reductase (dithiol) Amet_0665 8 None None None 150390268 Common - Polyprenyl synthetase Amet_2505 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 150389031 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Amet_1213 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150391794 Common - small GTP-binding protein Amet_4103 216 COG1160 COG1160, Predicted GTPases General function prediction only 150388891 Common - Chromate transporter Amet_1069 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 150392023 Common - putative undecaprenol kinase Amet_4339 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 150392401 Common - major facilitator superfamily MFS_1 Amet_4723 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150389076 Common - Transcriptional regulator IclR-like protein Amet_1260 124 COG1414 IclR, Transcriptional regulator Transcription 150391876 Common - glycoside hydrolase, family 4 Amet_4185 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150391678 Common - hypothetical protein Amet_3984 4 None None None 150391843 Common - NADH dehydrogenase (quinone) Amet_4152 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 150389314 Common - redox-sensing transcriptional repressor Rex Amet_1510 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 150389712 Nonpathogen - hypothetical protein Amet_1939 1 None None None 150391976 Common - RNA-directed DNA polymerase (Reverse transcriptase) Amet_4290 81 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150392271 Common - Domain of unknown function DUF1934 Amet_4590 13 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 150389830 Common - Cupin 2, conserved barrel domain protein Amet_2059 19 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 150388064 Nonpathogen - hypothetical protein Amet_0219 2 None None None 150390346 Common - protein of unknown function DUF968 Amet_2584 6 None None None 150390237 Common - Peptidoglycan glycosyltransferase Amet_2473 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150389419 Common - ATP-dependent metalloprotease FtsH Amet_1632 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150391909 Common - putative transcriptional regulator, MerR family Amet_4219 6 COG0789 SoxR, Predicted transcriptional regulators Transcription 150391107 Common - protein of unknown function DUF891 Amet_3369 27 COG4679 COG4679, Phage-related protein Function unknown 150388733 Common - short-chain dehydrogenase/reductase SDR Amet_0901 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150391777 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_4086 109 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150390435 Common - translation initiation factor IF-2 Amet_2673 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 150389341 Common - ABC transporter related Amet_1545 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150390444 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Amet_2682 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 150390064 Common - methylglyoxal synthase Amet_2297 87 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 150389093 Common - integral membrane sensor signal transduction histidine kinase Amet_1278 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150391454 Nonpathogen - conserved hypothetical protein, glutamine-rich Amet_3724 3 None None None 150388368 Common - Phosphoglycerate mutase Amet_0531 185 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150388356 Common - ABC transporter related Amet_0519 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 150389015 Common - GCN5-related N-acetyltransferase Amet_1197 35 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150391282 Common - hypothetical protein Amet_3546 19 None None None 150391740 Common - VRR_NUC domain protein Amet_4048 14 None None None 150388587 Common - metal dependent phosphohydrolase Amet_0752 110 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150389967 Common - protein of unknown function DUF45 Amet_2199 147 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 150391933 Common - sigma54 specific transcriptional regulator, Fis family Amet_4245 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150388268 Common - phage tail tape measure protein, TP901 family Amet_0430 19 COG5280 COG5280, Phage-related minor tail protein Function unknown 150388931 Common - transcriptional regulator, MarR family Amet_1110 54 COG1846 MarR, Transcriptional regulators Transcription 150390623 Common - Stage II sporulation P family protein Amet_2863 14 None None None 150392331 Common - MATE efflux family protein Amet_4651 175 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150388600 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Amet_0765 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150390316 Nonpathogen - hypothetical protein Amet_2554 1 None None None 150391853 Nonpathogen - hypothetical protein Amet_4162 1 None None None 150391058 Common - extracellular solute-binding protein, family 1 Amet_3320 76 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150391565 Common - microcompartments protein Amet_3838 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150390706 Common - glycogen/starch synthase, ADP-glucose type Amet_2946 143 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 150389613 Common - peptidase C26 Amet_1833 123 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 150389984 Common - stage V sporulation protein AA Amet_2216 4 None None None 150388021 Common - transcriptional regulator, XRE family Amet_0174 6 COG1396 HipB, Predicted transcriptional regulators Transcription 150390752 Common - AzlC family protein Amet_2998 96 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 150391007 Common - two component transcriptional regulator, winged helix family Amet_3259 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150388111 Common - Ethanolamine utilisation protein, EutH Amet_0268 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 150391571 Common - response regulator receiver protein Amet_3844 215 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150389671 Common - hypothetical protein Amet_1896 7 None None None 150390691 Common - putative transcriptional regulator, MerR family Amet_2931 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 150389505 Common - hypothetical protein Amet_1719 3 None None None 150387873 Common - 3H domain protein Amet_0020 16 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 150390301 Nonpathogen - hypothetical protein Amet_2538 1 None None None 150388293 Common - Alanine racemase Amet_0455 129 COG1609 PurR, Transcriptional regulators Transcription 150389268 Common - ABC transporter related Amet_1459 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150389593 Nonpathogen - hypothetical protein Amet_1813 1 None None None 150388282 Common - Uncharacterized membrane protein Amet_0444 8 COG3949 COG3949, Uncharacterized membrane protein Function unknown 150387952 Nonpathogen - bacteriocin, lactococcin 972 family Amet_0099 1 None None None 150387886 Common - single-strand binding protein Amet_0033 216 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150391235 Common - anion transporter Amet_3497 129 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 150392394 Nonpathogen - hypothetical protein Amet_4716 1 None None None 150388060 Common - hypothetical protein Amet_0215 8 None None None 150391727 Common - hypothetical protein Amet_4035 2 None None None 150391599 Common - amidohydrolase Amet_3889 55 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 150390854 Common - HflK protein Amet_3104 172 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 150392383 Common - TRAP transporter, 4TM/12TM fusion protein Amet_4705 119 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 150388187 Common - ATP synthase F0, C subunit Amet_0347 5 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 150389615 Nonpathogen - hypothetical protein Amet_1835 1 None None None 150388164 Common - ribosomal protein L31 Amet_0324 195 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 150389897 Nonpathogen - hypothetical protein Amet_2128 2 None None None 150388519 Common - uracil-xanthine permease Amet_0684 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150390962 Common - hypothetical protein Amet_3214 218 COG1048 AcnA, Aconitase A Energy production and conversion 150390505 Common - 16S rRNA processing protein RimM Amet_2744 166 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 150388849 Common - extracellular solute-binding protein, family 1 Amet_1022 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 150387896 Common - methyl-accepting chemotaxis sensory transducer Amet_0043 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150392408 Common - integral membrane sensor signal transduction histidine kinase Amet_4730 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150390362 Common - phage protein Amet_2600 10 None None None 150392008 Common - hypothetical protein Amet_4324 11 None None None 150389993 Common - GTP-binding protein, HSR1-related Amet_2225 221 COG2262 HflX, GTPases General function prediction only 150388510 Common - methyl-accepting chemotaxis sensory transducer Amet_0675 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150390298 Common - SOS-response transcriptional repressor, LexA Amet_2535 175 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150389416 Common - Sporulation protein YtxC Amet_1629 14 None None None 150389787 Nonpathogen - hypothetical protein Amet_2015 1 None None None 150389879 Common - hypothetical protein Amet_2110 2 None None None 150390217 Common - aminotransferase, class V Amet_2453 241 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 150387960 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_0108 151 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150390619 Common - hypothetical protein Amet_2859 9 None None None 150391051 Common - Na+/H+ antiporter NhaC Amet_3313 29 COG2056 COG2056, Predicted permease General function prediction only 150390897 Common - imidazolonepropionase Amet_3148 112 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 150392015 Common - protein of unknown function DUF1312 Amet_4331 10 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 150388789 Nonpathogen - hypothetical protein Amet_0961 1 None None None 150388558 Common - phosphoribosyltransferase Amet_0723 178 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 150392196 Common - UvrB/UvrC protein Amet_4514 19 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 150388200 Common - peptidase M23B Amet_0360 169 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150389212 Common - valyl-tRNA synthetase Amet_1402 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150391497 Common - protein of unknown function DUF1653 Amet_3768 35 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 150389606 Nonpathogen - hypothetical protein Amet_1826 1 None None None 150391046 Common - two component transcriptional regulator, winged helix family Amet_3307 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391208 Common - 6-phosphogluconolactonase Amet_3470 122 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 150391931 Common - protein of unknown function DUF1446 Amet_4243 35 None None None 150389057 Common - ABC transporter related Amet_1240 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150392421 Common - protein of unknown function DUF214 Amet_4745 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150388724 Common - PfkB domain protein Amet_0892 187 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150390609 Common - hypothetical protein Amet_2849 5 None None None 150388737 Nonpathogen - hypothetical protein Amet_0906 3 None None None 150388840 Common - histidine kinase Amet_1013 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150392076 Nonpathogen - hypothetical protein Amet_4392 1 None None None 150388633 Common - hypothetical protein Amet_0798 11 None None None 150390992 Nonpathogen - hypothetical protein Amet_3244 1 None None None 150388409 Common - Histidinol dehydrogenase Amet_0572 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 150389820 Common - ABC transporter related Amet_2049 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150388028 Nonpathogen - S-layer domain protein Amet_0181 7 None None None 150390157 Nonpathogen - hypothetical protein Amet_2393 1 None None None 150387945 Common - transcriptional regulator, AbrB family Amet_0092 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150389563 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Amet_1781 15 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 150389577 Common - hypothetical protein Amet_1797 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 150388701 Nonpathogen - hypothetical protein Amet_0866 1 None None None 150392264 Common - isochorismatase hydrolase Amet_4583 146 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 150390699 Nonpathogen - hypothetical protein Amet_2939 2 None None None 150391913 Common - Sporulation stage V, protein AE Amet_4223 15 None None None 150387931 Common - hypothetical protein Amet_0078 2 None None None 150390624 Nonpathogen - hypothetical protein Amet_2864 10 COG4089 COG4089, Predicted membrane protein Function unknown 150390686 Common - diguanylate cyclase/phosphodiesterase Amet_2926 173 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150388773 Nonpathogen - hypothetical protein Amet_0943 1 None None None 150387934 Common - Orn/Lys/Arg decarboxylase, major region Amet_0081 96 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 150388755 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Amet_0925 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 150389873 Nonpathogen - hypothetical protein Amet_2103 1 None None None 150392231 Common - D-Lysine 5,6-aminomutase alpha subunit Amet_4549 17 None None None 150388470 Nonpathogen - hypothetical protein Amet_0634 1 None None None 150388767 Nonpathogen - hypothetical protein Amet_0937 1 None None None 150391789 Common - molybdopterin oxidoreductase Amet_4098 199 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 150388856 Common - cell envelope-related transcriptional attenuator Amet_1029 63 COG1316 LytR, Transcriptional regulator Transcription 150391540 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_3812 124 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150389385 Common - hypothetical protein Amet_1596 5 None None None 150390766 Common - MATE efflux family protein Amet_3016 190 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150389388 Common - Group II intron, maturase-specific domain protein Amet_1601 84 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150388982 Common - phosphonate ABC transporter, ATPase subunit Amet_1162 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 150392024 Common - phage integrase domain protein SAM domain protein Amet_4340 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150388139 Common - OmpA/MotB domain protein Amet_0297 149 COG1360 MotB, Flagellar motor protein Cell motility and secretion 150389546 Nonpathogen - hypothetical protein Amet_1764 1 None None None 150391298 Nonpathogen - hypothetical protein Amet_3566 1 None None None 150389942 Common - hypothetical protein Amet_2173 50 COG3885 COG3885, Uncharacterized conserved protein Function unknown 150387922 Common - Precorrin-8X methylmutase CbiC/CobH Amet_0069 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 150389866 Nonpathogen - hypothetical protein Amet_2096 1 None None None 150390603 Common - hypothetical protein Amet_2843 4 None None None 150390187 Nonpathogen - hypothetical protein Amet_2423 1 None None None 150388662 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Amet_0827 140 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 150390855 Common - ATPase Amet_3105 10 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 150389987 Common - Sporulation stage V, protein AC Amet_2219 15 None None None 150391095 Common - adenylyltransferase Amet_3357 10 None None None 150387927 Common - precorrin-4 C11-methyltransferase Amet_0074 204 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 150388627 Common - protein of unknown function DUF327 Amet_0792 14 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 150390332 Common - hypothetical protein Amet_2570 2 None None None 150390518 Common - 2-nitropropane dioxygenase, NPD Amet_2757 147 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 150390521 Common - fatty acid biosynthesis transcriptional regulator Amet_2760 22 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 150389908 Common - Peptidase M15A Amet_2139 39 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 150391570 Common - signal transduction histidine kinase, LytS Amet_3843 102 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150388940 Common - extracellular solute-binding protein, family 5 Amet_1119 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150389339 Nonpathogen - hypothetical protein Amet_1542 1 None None None 150392410 Common - transposase IS3/IS911 family protein Amet_4732 6 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 150390813 Nonpathogen - hypothetical protein Amet_3063 1 None None None 150388628 Common - hypothetical protein Amet_0793 14 None None None 150389732 Common - hypothetical protein Amet_1959 3 None None None 150390547 Common - primosomal protein N' Amet_2787 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 150390674 Common - binding-protein-dependent transport systems inner membrane component Amet_2914 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150390031 Common - hypothetical protein Amet_2263 5 None None None 150389175 Common - cell cycle protein Amet_1365 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150389817 Common - binding-protein-dependent transport systems inner membrane component Amet_2046 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150388427 Common - Alcohol dehydrogenase, zinc-binding domain protein Amet_0590 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150391911 Common - hypothetical protein Amet_4221 2 None None None 150390277 Common - Exonuclease, RNase T and DNA polymerase III Amet_2514 11 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 150389898 Common - hypothetical protein Amet_2129 3 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 150391988 Common - thiamine pyrophosphate protein domain protein TPP-binding Amet_4304 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150390916 Common - MOSC domain containing protein Amet_3167 46 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 150389955 Common - transcriptional regulator, XRE family Amet_2186 3 COG1396 HipB, Predicted transcriptional regulators Transcription 150392014 Common - glutaredoxin 3 Amet_4330 129 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 150390194 Common - Baseplate J family protein Amet_2430 19 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150391052 Common - phage shock protein C, PspC Amet_3314 16 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 150388334 Nonpathogen - hypothetical protein Amet_0497 1 None None None 150389871 Nonpathogen - Protein of unknown function DUF1638 Amet_2101 4 None None None 150391337 Common - Alanine--glyoxylate transaminase Amet_3605 174 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 150391664 Nonpathogen - hypothetical protein Amet_3967 1 None None None 150391016 Common - SNARE associated Golgi protein Amet_3268 7 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150391701 Common - DNA-directed DNA polymerase Amet_4009 174 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 150391688 Common - arsenical-resistance protein Amet_3996 135 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 150390748 Common dnaG DNA primase Amet_2994 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 150389588 Nonpathogen - hypothetical protein Amet_1808 1 None None None 150392001 Common - aminotransferase class-III Amet_4317 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150389244 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Amet_1435 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150389349 Common - ABC transporter related Amet_1555 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150391708 Common - toxin secretion/phage lysis holin Amet_4016 13 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 150388395 Common - TRAP dicarboxylate transporter- DctP subunit Amet_0558 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 150389426 Common - phenylalanyl-tRNA synthetase, alpha subunit Amet_1639 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 150388708 Nonpathogen - hypothetical protein Amet_0876 1 None None None 150392212 Common - methyl-accepting chemotaxis sensory transducer Amet_4530 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150390480 Common - flagellar hook capping protein Amet_2718 107 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 150391786 Common - hypothetical protein Amet_4095 14 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 150389892 Nonpathogen - hypothetical protein Amet_2123 1 None None None 150389940 Common - histidyl-tRNA synthetase Amet_2171 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150391170 Nonpathogen - hypothetical protein Amet_3432 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150388186 Common - ATP synthase F0, A subunit Amet_0346 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 150389235 Common - VanW family protein Amet_1426 37 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 150388272 Nonpathogen - hypothetical protein Amet_0434 1 None None None 150389444 Common - iron-containing alcohol dehydrogenase Amet_1657 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150391996 Common - YbbR family protein Amet_4312 29 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 150391842 Common - NADH dehydrogenase (quinone) Amet_4151 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 150390721 Common - Auxin Efflux Carrier Amet_2961 147 COG0679 COG0679, Predicted permeases General function prediction only 150391644 Nonpathogen - hypothetical protein Amet_3943 4 None None None 150392291 Common - protein of unknown function DUF1021 Amet_4610 17 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 150389519 Common - ABC transporter related Amet_1733 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 150390661 Nonpathogen - hypothetical protein Amet_2901 1 None None None 150392111 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Amet_4429 114 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150388826 Common - Sec-independent protein translocase, TatC subunit Amet_0999 201 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 150391136 Common - ACT domain-containing protein Amet_3398 35 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 150389223 Common - GCN5-related N-acetyltransferase Amet_1413 18 COG0456 RimI, Acetyltransferases General function prediction only 150388145 Common - hypothetical protein Amet_0303 14 COG5305 COG5305, Predicted membrane protein Function unknown 150392253 Common - N-ethylammeline chlorohydrolase Amet_4572 179 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 150388408 Common - ATP phosphoribosyltransferase Amet_0571 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 150390454 Common - hypothetical protein Amet_2692 2 None None None 150389111 Common - putative cold-shock DNA-binding domain protein Amet_1296 183 COG1278 CspC, Cold shock proteins Transcription 150391960 Common - Coat F domain protein Amet_4272 2 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 150388239 Nonpathogen - hypothetical protein Amet_0401 1 None None None 150388506 Common - proline racemase Amet_0671 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 150388769 Nonpathogen - hypothetical protein Amet_0939 1 None None None 150390985 Common - hypothetical protein Amet_3237 7 COG0701 COG0701, Predicted permeases General function prediction only 150392032 Common - hypothetical protein Amet_4348 16 None None None 150391000 Nonpathogen - hypothetical protein Amet_3252 2 None None None 150391217 Nonpathogen - putative type IV pilin Amet_3479 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150389664 Nonpathogen - hypothetical protein Amet_1889 1 None None None 150389436 Common - Pyridoxal-5'-phosphate-dependent protein, beta subunit Amet_1649 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150389472 Nonpathogen - hypothetical protein Amet_1685 1 None None None 150389681 Common - alpha/beta hydrolase fold Amet_1907 189 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150388367 Common - Peptidase M15A Amet_0530 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 150389458 Common - cytidylyltransferase Amet_1671 2 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 150392119 Common - Rubrerythrin Amet_4437 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 150392321 Nonpathogen - hypothetical protein Amet_4640 4 None None None 150392164 Common - 30S ribosomal protein S7 Amet_4482 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 150389528 Common - BFD domain protein (2Fe-2S)-binding domain protein Amet_1743 20 None None None 150390400 Common - oxaloacetate decarboxylase Amet_2638 175 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 150391608 Common - peptidase M56, BlaR1 Amet_3901 23 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 150390938 Common - oxidoreductase FAD/NAD(P)-binding domain protein Amet_3190 167 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 150389302 Nonpathogen - copper amine oxidase domain protein Amet_1498 11 None None None 150392166 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Amet_4484 14 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 150388795 Nonpathogen - hypothetical protein Amet_0968 1 None None None 150391836 Common - alanine racemase Amet_4145 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 150390211 Nonpathogen - hypothetical protein Amet_2447 1 None None None 150391389 Common - GCN5-related N-acetyltransferase Amet_3657 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150389490 Common - competence damage-inducible protein A Amet_1704 213 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 150390647 Common - S-adenosyl-methyltransferase MraW Amet_2887 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 150392128 Common - ABC transporter related Amet_4446 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150389974 Common - thiamine biosynthesis/tRNA modification protein ThiI Amet_2206 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 150391558 Common - ethanolamine utilization protein EutJ family protein Amet_3831 87 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 150391312 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Amet_3580 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 150391025 Nonpathogen - hypothetical protein Amet_3278 1 None None None 150391445 Common - two component transcriptional regulator, LuxR family Amet_3715 215 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150388207 Common - S-layer domain-like protein Amet_0367 17 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 150390876 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_3127 177 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150389752 Common - lipolytic protein, G-D-S-L family Amet_1979 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150389917 Nonpathogen - hypothetical protein Amet_2148 1 None None None 150388932 Common - MATE efflux family protein Amet_1111 176 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150389653 Common - binding-protein-dependent transport systems inner membrane component Amet_1878 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150389453 Common - CRISPR-associated protein Cas4 Amet_1666 52 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 150389513 Nonpathogen - hypothetical protein Amet_1727 1 None None None 150391188 Common - glycosyl transferase, family 2 Amet_3450 54 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150389401 Common - polysaccharide deacetylase Amet_1614 7 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150389827 Common - MATE efflux family protein Amet_2056 134 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150389066 Common - thiW protein Amet_1250 16 COG4732 COG4732, Predicted membrane protein Function unknown 150389089 Common - SNARE associated Golgi protein Amet_1273 95 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150390953 Common - lipoyltransferase and lipoate-protein ligase Amet_3205 85 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 150392281 Common - GerA spore germination protein Amet_4600 15 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 150390104 Common - SpoIID/LytB domain protein Amet_2340 45 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 150388831 Common - superfamily I DNA helicase Amet_1004 70 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 150391397 Nonpathogen - hypothetical protein Amet_3667 1 None None None 150391849 Common - multiple resistance and pH regulation protein F Amet_4158 71 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 150392172 Common - ribosomal protein L11 Amet_4490 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 150388412 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Amet_0575 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 150392475 Common - 60 kDa inner membrane insertion protein Amet_4799 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 150388222 Nonpathogen - hypothetical protein Amet_0384 1 None None None 150390668 Common - Nickel-transporting ATPase Amet_2908 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391148 Common - Citryl-CoA lyase Amet_3410 113 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 150392469 Common - protein of unknown function UPF0016 Amet_4793 18 COG2119 COG2119, Predicted membrane protein Function unknown 150390426 Common - Sporulation protein YlmC/YmxH Amet_2664 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 150389052 Nonpathogen - GCN5-related N-acetyltransferase Amet_1235 2 COG0456 RimI, Acetyltransferases General function prediction only 150390411 Common - spermidine synthase Amet_2649 131 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 150392092 Nonpathogen - hypothetical protein Amet_4409 1 None None None 150388543 Common - two component transcriptional regulator, winged helix family Amet_0708 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150389354 Common - protein of unknown function DUF418 Amet_1560 46 COG2311 COG2311, Predicted membrane protein Function unknown 150390027 Nonpathogen - hypothetical protein Amet_2259 1 None None None 150391247 Common - Threonine aldolase Amet_3510 93 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 150388687 Common - hypothetical protein Amet_0852 5 None None None 150390842 Common - MaoC domain protein dehydratase Amet_3092 100 COG2030 MaoC, Acyl dehydratase Lipid metabolism 150391669 Common - hypothetical protein Amet_3974 2 None None None 150389152 Common - acriflavin resistance protein Amet_1341 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150391827 Common - hypothetical protein Amet_4136 5 None None None 150391430 Common - metal dependent phosphohydrolase Amet_3700 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150391811 Common - hypothetical protein Amet_4120 4 None None None 150392416 Common - hypothetical protein Amet_4740 17 None None None 150388451 Common - flagellar biosynthesis protein FlhA Amet_0615 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 150390015 Nonpathogen - hypothetical protein Amet_2247 1 None None None 150388591 Common - HEPN domain protein Amet_0756 14 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 150389390 Common - reverse transcriptase Amet_1603 35 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150391718 Common - uncharacterized phage protein Amet_4026 5 None None None 150388945 Common - Protein of unknown function CGGC region Amet_1124 5 COG5561 COG5561, Predicted metal-binding protein Function unknown 150391954 Common - transcriptional coactivator/pterin dehydratase Amet_4266 109 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 150388692 Nonpathogen - hypothetical protein Amet_0857 1 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 150391924 Common - thiazole biosynthesis protein ThiH Amet_4234 61 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 150391957 Common - PTS system, mannitol-specific IIC subunit Amet_4269 76 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 150388242 Nonpathogen - hypothetical protein Amet_0404 1 None None None 150389886 Nonpathogen - hypothetical protein Amet_2117 1 None None None 150388989 Common - hypothetical protein Amet_1170 26 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 150388672 Common - protein of unknown function DUF955 Amet_0837 7 None None None 150391123 Common - response regulator receiver and ANTAR domain protein Amet_3385 176 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 150392246 Common - conserved hypothetical protein, possibly involved in molybdenum cofactor biosynthesis Amet_4565 68 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 150388491 Common - two component transcriptional regulator, winged helix family Amet_0656 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150391122 Common - methionine-R-sulfoxide reductase Amet_3384 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150389706 Nonpathogen - hypothetical protein Amet_1933 1 None None None 150389102 Nonpathogen - hypothetical protein Amet_1287 1 None None None 150391582 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Amet_3859 59 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150390291 Common - Serine-type D-Ala-D-Ala carboxypeptidase Amet_2528 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150392215 Common - sigma54 specific transcriptional regulator, Fis family Amet_4533 175 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150389936 Nonpathogen - hypothetical protein Amet_2167 1 None None None 150391870 Common - metal dependent phosphohydrolase Amet_4179 44 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 150391588 Nonpathogen - hypothetical protein Amet_3865 1 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 150390831 Common - MgtC/SapB transporter Amet_3081 121 COG1285 SapB, Uncharacterized membrane protein Function unknown 150389271 Common - peroxiredoxin-like protein Amet_1462 59 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150391202 Common - protein of unknown function DUF1456 Amet_3464 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 150391866 Nonpathogen - hypothetical protein Amet_4175 1 None None None 150388455 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_0619 56 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150391341 Common - 5'-Nucleotidase domain protein Amet_3609 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150389160 Nonpathogen - hypothetical protein Amet_1350 2 None None None 150389148 Nonpathogen - hypothetical protein Amet_1336 1 None None None 150389949 Common - protein of unknown function UPF0118 Amet_2180 193 COG0628 PerM, Predicted permease General function prediction only 150390000 Common - permease Amet_2232 22 COG0730 COG0730, Predicted permeases General function prediction only 150388276 Common - hypothetical protein Amet_0438 3 None None None 150390378 Common - Resolvase, N-terminal domain Amet_2616 140 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150390528 Common - pantetheine-phosphate adenylyltransferase Amet_2767 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 150392099 Nonpathogen - hypothetical protein Amet_4417 1 None None None 150390343 Nonpathogen - hypothetical protein Amet_2581 2 None None None 150391154 Common - methylaspartate mutase subunit S Amet_3416 18 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 150392225 Common - ATP-dependent metalloprotease FtsH Amet_4543 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150388573 Nonpathogen - hypothetical protein Amet_0738 1 None None None 150390733 Common - Allophanate hydrolase subunit 1 Amet_2974 115 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 150391195 Common - 3-isopropylmalate dehydratase, large subunit Amet_3457 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 150387991 Common - hypothetical protein Amet_0142 3 None None None 150391129 Common - nitrogen regulatory protein P-II Amet_3391 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150391621 Common - transcription activator, effector binding Amet_3916 9 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150387867 Nonpathogen - hypothetical protein Amet_0014 11 None None None 150391059 Common - response regulator receiver protein Amet_3321 222 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150387993 Nonpathogen - hypothetical protein Amet_0144 1 None None None 150388665 Common - GCN5-related N-acetyltransferase Amet_0830 9 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 150389149 Common - hypothetical protein Amet_1337 43 COG2210 COG2210, Uncharacterized conserved protein Function unknown 150390829 Common - ABC transporter related Amet_3079 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150389575 Common - hypothetical protein Amet_1794 6 None None None 150390396 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Amet_2634 119 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150390076 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Amet_2309 191 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 150388912 Common - ADP-ribosylation/Crystallin J1 Amet_1090 38 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 150389099 Common - spore germination B3 GerAC family protein Amet_1284 15 None None None 150392042 Common - hypothetical protein Amet_4358 5 None None None 150391468 Common - hypothetical protein Amet_3739 22 COG4895 COG4895, Uncharacterized conserved protein Function unknown 150388385 Nonpathogen - hypothetical protein Amet_0548 1 None None None 150390154 Nonpathogen - hypothetical protein Amet_2390 3 None None None 150389960 Common - CRISPR-associated autoregulator, DevR family Amet_2191 13 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150390867 Common - KWG Leptospira repeat protein Amet_3118 9 None None None 150389803 Common - hypothetical protein Amet_2031 7 None None None 150390885 Nonpathogen - hypothetical protein Amet_3136 1 None None None 150392356 Nonpathogen - hypothetical protein Amet_4678 1 None None None 150388539 Common - signal transduction histidine kinase regulating citrate/malate metabolism Amet_0704 141 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150389690 Common - integral membrane sensor signal transduction histidine kinase Amet_1916 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150388054 Common - glycosyl transferase, group 1 Amet_0209 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150389323 Nonpathogen - hypothetical protein Amet_1520 6 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 150388317 Common - 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase Amet_0480 89 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 150391031 Common - Rhodanese domain protein Amet_3290 67 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150388646 Common - redox-sensing transcriptional repressor Rex Amet_0811 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 150388807 Common - conserved hypothetical protein, CF-27 family Amet_0980 12 None None None 150388889 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Amet_1067 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150389550 Nonpathogen - hypothetical protein Amet_1768 1 None None None 150388257 Common - hypothetical protein Amet_0419 2 None None None 150389630 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Amet_1851 152 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150390927 Nonpathogen - hypothetical protein Amet_3179 1 None None None 150391287 Common - protein of unknown function DUF214 Amet_3553 16 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 150388880 Nonpathogen - hypothetical protein Amet_1058 1 None None None 150388178 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Amet_0338 129 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 150389637 Nonpathogen - hypothetical protein Amet_1858 1 None None None 150388085 Nonpathogen - hypothetical protein Amet_0242 2 None None None 150390917 Common - molybdenum cofactor synthesis domain Amet_3168 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 150388498 Common - sigma54 specific transcriptional regulator, Fis family Amet_0663 200 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150389521 Common - binding-protein-dependent transport systems inner membrane component Amet_1735 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150392307 Common - protein of unknown function DUF6, transmembrane Amet_4626 98 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150387977 Nonpathogen - hypothetical protein Amet_0128 1 None None None 150391412 Common - conserved hypothetical radical SAM protein Amet_3682 65 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 150389607 Common - regulatory protein, ArsR Amet_1827 72 COG0640 ArsR, Predicted transcriptional regulators Transcription 150388941 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Amet_1120 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150391829 Common - protein of unknown function DUF161 Amet_4138 69 COG1284 COG1284, Uncharacterized conserved protein Function unknown 150392206 Common - lysyl-tRNA synthetase Amet_4524 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150390410 Common - S-adenosylmethionine decarboxylase related Amet_2648 69 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 150388839 Common - PAS/PAC sensor signal transduction histidine kinase Amet_1012 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150389628 Nonpathogen - hypothetical protein Amet_1848 1 None None None 150389701 Nonpathogen - hypothetical protein Amet_1928 1 None None None 150390246 Nonpathogen - hypothetical protein Amet_2483 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 150390554 Common - Fibronectin-binding A domain protein Amet_2794 89 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 150388749 Common - phosphoribosylformylglycinamidine synthase, purS Amet_0919 108 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 150391365 Common - signal peptidase I Amet_3633 140 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150389506 Nonpathogen - hypothetical protein Amet_1720 1 None None None 150392130 Common - ribosomal protein L17 Amet_4448 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 150390640 Common - stage V sporulation protein E Amet_2880 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150392460 Common - uncharacterized membrane protein-like protein Amet_4784 23 COG3949 COG3949, Uncharacterized membrane protein Function unknown 150392139 Common - Nucleoside-triphosphate--adenylate kinase Amet_4457 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 150390387 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Amet_2625 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 150391101 Common - putative transposase Amet_3363 32 None None None 150388089 Nonpathogen - hypothetical protein Amet_0246 2 None None None 150388616 Common - TRAP transporter, 4TM/12TM fusion protein Amet_0781 116 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 150388528 Nonpathogen - hypothetical protein Amet_0693 4 None None None 150390775 Nonpathogen - hypothetical protein Amet_3025 1 None None None 150388349 Common - spore germination B3 GerAC family protein Amet_0512 15 None None None 150388303 Common - uracil-xanthine permease Amet_0465 128 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150388916 Common - heavy metal translocating P-type ATPase Amet_1094 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150392081 Nonpathogen - hypothetical protein Amet_4398 1 None None None 150389399 Common - transposase, mutator type Amet_1612 90 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 150387917 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Amet_0064 77 COG2138 COG2138, Uncharacterized conserved protein Function unknown 150389296 Nonpathogen - hypothetical protein Amet_1490 1 None None None 150389184 Nonpathogen - hypothetical protein Amet_1374 1 None None None 150389337 Common - hypothetical protein Amet_1537 2 None None None 150391409 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Amet_3679 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 150392058 Common - cell wall hydrolase/autolysin Amet_4374 37 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150390197 Nonpathogen - hypothetical protein Amet_2433 1 None None None 150388917 Nonpathogen - hypothetical protein Amet_1095 2 None None None 150390487 Common - flagellar M-ring protein FliF Amet_2725 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 150389718 Common - cell wall hydrolase/autolysin Amet_1945 37 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane