Clostridium beijerinckii NCIMB 8052, complete genome NC_009617 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 150017022 Common - transcriptional regulator, MarR family Cbei_2153 66 COG1846 MarR, Transcriptional regulators Transcription 150018870 Common - microcompartments protein Cbei_4058 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150015116 Common - Transketolase domain protein Cbei_0224 222 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 150018780 Common - TPR repeat-containing protein Cbei_3968 2 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 150018759 Common - transcriptional regulator, HxlR family Cbei_3947 137 COG1733 COG1733, Predicted transcriptional regulators Transcription 150015764 Common - Resolvase, N-terminal domain Cbei_0878 109 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150017603 Common - molybdate metabolism regulator Cbei_2750 9 None None None 150014898 Common gyrB DNA gyrase subunit B Cbei_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 150018478 Common - protein of unknown function DUF6, transmembrane Cbei_3658 13 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 150015361 Common - putative endoribonuclease L-PSP Cbei_0471 176 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 150016693 Nonpathogen - hypothetical protein Cbei_1820 1 None None None 150017530 Common - coagulation factor 5/8 type domain protein Cbei_2675 22 None None None 150017914 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Cbei_3075 188 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150018615 Common - hydrogenase, Fe-only Cbei_3796 50 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150015440 Common - Phosphomannomutase Cbei_0550 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150016273 Common - membrane protein Cbei_1392 2 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 150016761 Nonpathogen - GRound-like protein Cbei_1888 1 COG4907 COG4907, Predicted membrane protein Function unknown 150019127 Common - transposase, IS4 family protein Cbei_4315 17 None None None 150014893 Common dnaA chromosomal replication initiation protein Cbei_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 150016898 Common - osmosensitive K+ channel signal transduction histidine kinase Cbei_2027 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150015784 Nonpathogen - hypothetical protein Cbei_0898 1 None None None 150016909 Common - sigma54 specific transcriptional regulator, Fis family Cbei_2039 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150017017 Common - dihydroxyacetone kinase, DhaK subunit Cbei_2148 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 150019299 Common - hydroxyethylthiazole kinase Cbei_4488 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 150017614 Nonpathogen - hypothetical protein Cbei_2761 7 None None None 150018563 Common - UviB-like protein Cbei_3744 2 None None None 150014947 Common - methionyl-tRNA synthetase Cbei_0055 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017992 Nonpathogen - HNH endonuclease Cbei_3157 1 None None None 150015687 Common - DNA polymerase I Cbei_0801 219 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 150015159 Nonpathogen - signal transduction histidine kinase regulating citrate/malate metabolism Cbei_0268 2 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150017760 Common - MORN repeat-containing protein Cbei_2915 29 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 150018729 Common - transcriptional regulator, MarR family Cbei_3915 54 COG1846 MarR, Transcriptional regulators Transcription 150017455 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cbei_2597 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150015100 Common - protein of unknown function DUF124 Cbei_0208 26 COG2013 COG2013, Uncharacterized conserved protein Function unknown 150016001 Common - cell division protein FtsA Cbei_1117 175 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 150017500 Common - hypothetical protein Cbei_2644 1 None None None 150019748 Common - spermidine/putrescine ABC transporter ATPase subunit Cbei_4940 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 150018400 Common - RNA polymerase factor sigma-70 Cbei_3576 34 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150017938 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3099 29 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015188 Common - hypothetical protein Cbei_0298 5 None None None 150016460 Common - Polypeptide-transport-associated domain protein, FtsQ-type Cbei_1584 17 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 150016283 Common - metal-dependent hydrolase of the beta-lactamase superfamily Cbei_1403 27 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 150016341 Nonpathogen - hypothetical protein Cbei_1461 1 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 150016295 Common - hypothetical protein Cbei_1415 5 None None None 150017836 Common - NADH-quinone oxidoreductase, B subunit Cbei_2995 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 150018231 Common - integral membrane sensor hybrid histidine kinase Cbei_3403 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015408 Common - aspartate-semialdehyde dehydrogenase Cbei_0518 183 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 150015513 Common - ABC transporter related Cbei_0624 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 150016540 Common - hypothetical protein Cbei_1664 1 None None None 150015741 Common - protein of unknown function DUF34 Cbei_0855 152 COG0327 COG0327, Uncharacterized conserved protein Function unknown 150015336 Common - L-rhamnose isomerase Cbei_0446 23 COG4806 RhaA, L-rhamnose isomerase Carbohydrate transport and metabolism 150017626 Common - hypothetical protein Cbei_2773 6 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 150016148 Common - cobalamin biosynthesis protein CobU, putative, truncation Cbei_1266 2 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 150017788 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_2945 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 150015095 Common - phosphate butyryltransferase Cbei_0203 153 COG0280 Pta, Phosphotransacetylase Energy production and conversion 150015750 Common - 4-alpha-glucanotransferase Cbei_0864 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 150019799 Common - phage minor structural protein Cbei_4991 8 COG4926 PblB, Phage-related protein Function unknown 150019225 Common - hypothetical protein Cbei_4414 1 None None None 150017043 Common - arsenate reductase and related Cbei_2174 30 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 150017055 Common - methyl-accepting chemotaxis sensory transducer Cbei_2186 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019130 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Cbei_4318 114 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150016063 Common trmD tRNA (guanine-N(1)-)-methyltransferase Cbei_1179 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 150017999 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3165 138 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150014905 Common - ATP-dependent nuclease subunit AddB Cbei_0013 32 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 150016965 Common - AMP-dependent synthetase and ligase Cbei_2096 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150015562 Nonpathogen - NAD-dependent aldehyde dehydrogenase-like protein Cbei_0674 4 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150018170 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3341 125 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150016652 Common - hypothetical protein Cbei_1779 11 None None None 150016598 Common - glycosyl transferase, family 2 Cbei_1724 207 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150016908 Common - MaoC domain protein dehydratase Cbei_2038 84 COG2030 MaoC, Acyl dehydratase Lipid metabolism 150018747 Common - putative galactoside ABC transporter Cbei_3935 49 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018342 Common - ROK family protein Cbei_3517 169 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150017877 Common - putative cell wall binding repeat-containing protein Cbei_3036 3 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016880 Common - Radical SAM domain protein Cbei_2008 203 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150017622 Common - Extracellular ligand-binding receptor Cbei_2769 161 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 150019546 Common - Glycosyltransferase 28, C-terminal domain Cbei_4736 15 COG5017 COG5017, Uncharacterized conserved protein Function unknown 150015608 Common - transcriptional regulator, LysR family Cbei_0722 189 COG0583 LysR, Transcriptional regulator Transcription 150016732 Common - short-chain dehydrogenase/reductase SDR Cbei_1859 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150019242 Common - response regulator receiver protein Cbei_4431 222 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150017817 Common - methyl-accepting chemotaxis sensory transducer Cbei_2975 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017321 Common - methionine sulfoxide reductase B Cbei_2461 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150017823 Common - hypothetical protein Cbei_2981 1 None None None 150019054 Common - hypothetical protein Cbei_4242 1 None None None 150017011 Common - major facilitator superfamily MFS_1 Cbei_2142 172 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 150019152 Nonpathogen - hypothetical protein Cbei_4340 1 None None None 150014923 Common - metal dependent phosphohydrolase Cbei_0031 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150017084 Common - hypothetical protein Cbei_2216 1 None None None 150017435 Nonpathogen - hypothetical protein Cbei_2577 1 None None None 150018224 Common - Phage XkdN-like protein Cbei_3396 1 None None None 150016547 Nonpathogen - hypothetical protein Cbei_1672 1 None None None 150017002 Nonpathogen - hypothetical protein Cbei_2133 1 None None None 150017638 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_2786 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017744 Common - response regulator receiver protein Cbei_2897 221 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150015317 Common - hypothetical protein Cbei_0427 1 None None None 150015449 Common - ExsB family protein Cbei_0560 79 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 150018202 Common - hypothetical protein Cbei_3374 3 None None None 150019677 Common - protein of unknown function DUF161 Cbei_4869 63 COG1284 COG1284, Uncharacterized conserved protein Function unknown 150015216 Common - 8-oxoguanine DNA glycosylase domain protein Cbei_0326 23 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 150017968 Common - regulatory protein GntR, HTH Cbei_3130 100 COG2188 PhnF, Transcriptional regulators Transcription 150016638 Common - inner-membrane translocator Cbei_1764 151 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 150019290 Common - Glycerate kinase Cbei_4479 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 150018792 Common - binding-protein-dependent transport systems inner membrane component Cbei_3980 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150016402 Common - sodium:dicarboxylate symporter Cbei_1524 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 150017695 Common - two component transcriptional regulator, winged helix family Cbei_2845 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017404 Common - NUDIX hydrolase Cbei_2546 127 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 150015169 Common - methyl-accepting chemotaxis sensory transducer Cbei_0279 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016489 Common - hypothetical protein Cbei_1613 3 None None None 150018668 Common - hypothetical protein Cbei_3851 3 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150018290 Common - Methyltransferase type 12 Cbei_3463 23 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150015698 Common - anti-sigma-factor antagonist Cbei_0812 46 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 150019148 Common - aminotransferase, class V Cbei_4336 148 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 150019503 Common - hypothetical protein Cbei_4693 1 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150017510 Common - TPR repeat-containing protein Cbei_2655 5 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 150018804 Common - protein of unknown function DUF21 Cbei_3992 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150014998 Common - glycyl-tRNA synthetase Cbei_0106 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150018291 Common - hypothetical protein Cbei_3464 2 None None None 150018899 Common - ABC transporter, periplasmic substrate-binding protein Cbei_4087 6 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 150017839 Nonpathogen - hypothetical protein Cbei_2998 2 None None None 150016824 Nonpathogen - hypothetical protein Cbei_1952 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150019376 Common - ROK family protein Cbei_4565 154 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150019058 Common flgG flagellar basal body rod protein FlgG Cbei_4246 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 150019627 Common - hemerythrin-like metal-binding protein Cbei_4818 25 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150016519 Common - hypothetical protein Cbei_1643 2 None None None 150017640 Common - putative cold-shock DNA-binding domain protein Cbei_2788 170 COG1278 CspC, Cold shock proteins Transcription 150019073 Common - flagellar operon protein Cbei_4261 16 None None None 150018594 Common - two component transcriptional regulator, winged helix family Cbei_3775 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017064 Common - phosphotransferase system PTS, sorbose-specific IIC subunit Cbei_2195 31 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150015421 Common - Mannitol dehydrogenase, C-terminal domain Cbei_0531 60 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150016817 Common - putative signal-transduction protein with CBS domains Cbei_1945 213 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 150019114 Common - flagellar motor switch protein Cbei_4302 125 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 150017961 Common - ABC transporter related Cbei_3123 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 150019741 Common - iron-containing alcohol dehydrogenase Cbei_4933 59 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150017479 Nonpathogen - hypothetical protein Cbei_2623 1 None None None 150019657 Common - putative galactoside ABC transporter, periplasmic D-galactose/D-glucose-binding protein Cbei_4849 53 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015437 Common - Ribulose-phosphate 3-epimerase Cbei_0547 217 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150015103 Common - hypothetical protein Cbei_0211 1 None None None 150018364 Common - ABC transporter related Cbei_3540 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 150015348 Common - Cof-like hydrolase Cbei_0458 134 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150016367 Common - pentapeptide repeat protein Cbei_1488 92 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150019016 Common - Glutamate synthase (ferredoxin) Cbei_4204 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 150019446 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_4636 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150015680 Common - nicotinate-nucleotide pyrophosphorylase Cbei_0794 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 150018648 Common - DTW domain containing protein Cbei_3831 41 COG3148 COG3148, Uncharacterized conserved protein Function unknown 150016936 Common - phosphoenolpyruvate synthase Cbei_2066 184 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150017923 Common - protein of unknown function DUF1234 Cbei_3084 22 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 150019106 Common - flagellar protein FlaG protein Cbei_4294 9 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 150017112 Nonpathogen - hypothetical protein Cbei_2247 1 None None None 150019486 Common - response regulator receiver protein Cbei_4676 212 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150019466 Common - major facilitator superfamily MFS_1 Cbei_4656 68 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150019850 Common - Extracellular ligand-binding receptor Cbei_5042 161 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 150016079 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cbei_1195 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 150018809 Common - alpha/beta hydrolase fold Cbei_3997 159 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150017333 Common - two component transcriptional regulator, winged helix family Cbei_2474 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017036 Nonpathogen - hypothetical protein Cbei_2167 1 None None None 150017575 Common - protein of unknown function DUF1232 Cbei_2722 25 COG3339 COG3339, Uncharacterized conserved protein Function unknown 150017202 Common - hypothetical protein Cbei_2340 2 None None None 150019574 Common - putative cell wall binding repeat-containing protein Cbei_4765 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017781 Common - Chloride channel, core Cbei_2937 134 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 150018697 Common - regulatory protein, LacI Cbei_3881 122 COG1609 PurR, Transcriptional regulators Transcription 150015547 Common - Accessory gene regulator B Cbei_0658 3 None None None 150017828 Common - proton-translocating NADH-quinone oxidoreductase, chain M Cbei_2987 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 150018631 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_3812 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150019213 Common - FHA domain containing protein Cbei_4402 5 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 150019066 Common - bifunctional flagellar biosynthesis protein FliR/FlhB Cbei_4254 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 150015503 Common - binding-protein-dependent transport systems inner membrane component Cbei_0614 165 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150018971 Common - regulatory protein, LuxR Cbei_4159 38 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 150015474 Common - Cysteine desulfurase Cbei_0585 220 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150017191 Common - Methionine synthase, vitamin-B12 independent Cbei_2329 48 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 150019210 Nonpathogen - hypothetical protein Cbei_4399 1 None None None 150015655 Common - extracellular solute-binding protein, family 1 Cbei_0769 44 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015044 Common rplD 50S ribosomal protein L4 Cbei_0152 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 150015596 Common - histidine kinase Cbei_0710 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015333 Common - ROK family protein Cbei_0443 96 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150017245 Common - xylose isomerase Cbei_2383 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 150018399 Common - hypothetical protein Cbei_3575 2 None None None 150018385 Common - 5-aminoimidazole-4-carboxamide ribonucleotide transformylase Cbei_3561 217 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 150016232 Nonpathogen - hypothetical protein Cbei_1350 2 None None None 150017540 Common - Abortive infection protein Cbei_2685 13 None None None 150018357 Common - transcriptional regulator, HxlR family Cbei_3533 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 150019284 Common - metal dependent phosphohydrolase Cbei_4473 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150019081 Common - flagellar hook-basal body complex subunit FliE Cbei_4269 34 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 150018208 Common - putative cell wall binding repeat-containing protein Cbei_3380 2 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018436 Common - hypothetical protein Cbei_3614 25 COG4257 Vgb, Streptogramin lyase Defense mechanisms 150015880 Common - translation-associated GTPase Cbei_0994 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 150015276 Common - glycosyl transferase, group 1 Cbei_0386 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150015887 Common - aspartate carbamoyltransferase regulatory subunit Cbei_1001 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 150018981 Common - two component transcriptional regulator, winged helix family Cbei_4169 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016978 Common - Arsenical resistance operon trans-acting repressor ArsD Cbei_2109 31 None None None 150015083 Common - TPR repeat-containing protein Cbei_0191 40 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150017175 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Cbei_2313 64 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 150018169 Common - hypothetical protein Cbei_3340 1 None None None 150018390 Common - UBA/Ts-N domain protein Cbei_3566 4 None None None 150019400 Common leuS leucyl-tRNA synthetase Cbei_4590 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017421 Common - RNA chaperone Hfq Cbei_2563 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 150014986 Common - Spore cortex biosynthesis protein YabQ Cbei_0094 3 None None None 150016558 Nonpathogen - hypothetical protein Cbei_1684 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 150018734 Common - putative galactoside ABC transporter Cbei_3920 70 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016173 Common - lipase Cbei_1291 76 COG0657 Aes, Esterase/lipase Lipid metabolism 150017413 Common - tRNA-i(6)A37 thiotransferase enzyme MiaB Cbei_2555 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150019011 Common - isocitrate dehydrogenase Cbei_4199 82 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 150019493 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_4683 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150015156 Nonpathogen - hypothetical protein Cbei_0265 1 None None None 150016595 Common - metallophosphoesterase Cbei_1721 82 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150017221 Common - Monosaccharide-transporting ATPase Cbei_2359 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150018008 Nonpathogen - hypothetical protein Cbei_3175 2 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150018186 Common - integral membrane sensor signal transduction histidine kinase Cbei_3358 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019316 Common - putative cell wall binding repeat-containing protein Cbei_4505 3 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017701 Common - isochorismatase hydrolase Cbei_2852 108 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 150019566 Common - Undecaprenyl-phosphate galactose phosphotransferase Cbei_4757 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150017635 Common - hypothetical protein Cbei_2782 3 None None None 150015354 Common - hypothetical protein Cbei_0464 20 COG3601 COG3601, Predicted membrane protein Function unknown 150017133 Common - transcriptional regulator, AbrB family Cbei_2270 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150019432 Common - putative cell wall binding repeat-containing protein Cbei_4622 4 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017368 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_2510 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150017717 Common - acetolactate synthase Cbei_2868 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150018536 Common - Methyltransferase type 11 Cbei_3717 25 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150019475 Common - glycoside hydrolase, family 25 Cbei_4665 41 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150019259 Common - Monosaccharide-transporting ATPase Cbei_4448 112 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 150015839 Common - sigma-54 factor, interaction domain-containing protein Cbei_0953 159 COG3933 COG3933, Transcriptional antiterminator Transcription 150019433 Common - putative cell wall binding repeat-containing protein Cbei_4623 7 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015482 Common - tRNA/rRNA methyltransferase (SpoU) Cbei_0593 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 150018610 Common - MOSC domain containing protein Cbei_3791 40 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 150016944 Common - GCN5-related N-acetyltransferase Cbei_2074 68 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150016739 Common - hypothetical protein Cbei_1866 17 COG3610 COG3610, Uncharacterized conserved protein Function unknown 150018246 Common - nitroreductase Cbei_3418 62 COG0778 NfnB, Nitroreductase Energy production and conversion 150015937 Common - ABC transporter related Cbei_1051 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150017312 Common - RnfA-Nqr electron transport subunit Cbei_2452 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 150019902 Common - parB-like partition protein Cbei_5094 190 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150016093 Common - peptidase M16 domain protein Cbei_1209 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150017236 Common - membrane protein; CF-9 family Cbei_2374 4 None None None 150016591 Common - hypothetical protein Cbei_1717 1 None None None 150018657 Nonpathogen - hypothetical protein Cbei_3840 1 None None None 150017302 Common - Phosphoesterase, HXTX Cbei_2442 4 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 150016479 Nonpathogen - hypothetical protein Cbei_1603 1 None None None 150017260 Common - two component transcriptional regulator, winged helix family Cbei_2400 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150018583 Common - sugar (Glycoside-Pentoside-Hexuronide) transporter Cbei_3764 87 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150018113 Nonpathogen - hypothetical protein Cbei_3283 1 None None None 150017585 Common - histidine kinase Cbei_2732 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015758 Common - methyl-accepting chemotaxis sensory transducer Cbei_0872 133 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016839 Common - peptidase Cbei_1967 122 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 150019804 Common - helix-turn-helix domain protein Cbei_4996 17 COG1709 COG1709, Predicted transcriptional regulator Transcription 150015055 Common rplE 50S ribosomal protein L5 Cbei_0163 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 150017361 Common - NAD-dependent glycerol-3-phosphate dehydrogenase domain protein Cbei_2503 79 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 150015553 Common - alpha amylase, catalytic region Cbei_0664 23 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150017554 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_2700 94 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150015706 Common holA DNA polymerase III subunit delta Cbei_0820 42 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 150016679 Nonpathogen - hypothetical protein Cbei_1806 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150019232 Common - galactose-1-phosphate uridylyltransferase Cbei_4421 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 150015665 Common - transcriptional regulator, MarR family Cbei_0779 122 COG1846 MarR, Transcriptional regulators Transcription 150015803 Common - hypothetical protein Cbei_0917 16 COG5280 COG5280, Phage-related minor tail protein Function unknown 150017428 Common - hypothetical protein Cbei_2570 6 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 150016277 Common - BAAT/Acyl-CoA thioester hydrolase-like protein Cbei_1396 20 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 150017237 Common - putative transcriptional regulator, AsnC family Cbei_2375 88 COG1522 Lrp, Transcriptional regulators Transcription 150015291 Common - ribosomal protein L31 Cbei_0401 188 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 150019157 Common - Succinylglutamate desuccinylase/aspartoacylase Cbei_4345 32 COG3608 COG3608, Predicted deacylase General function prediction only 150018676 Common - pyruvate phosphate dikinase, PEP/pyruvate-binding Cbei_3859 200 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150014934 Common - two component transcriptional regulator, winged helix family Cbei_0042 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150019664 Common - protein of unknown function UPF0052 and CofD Cbei_4856 96 COG0391 COG0391, Uncharacterized conserved protein Function unknown 150018683 Common - integral membrane sensor signal transduction histidine kinase Cbei_3866 125 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150016727 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_1854 12 None None None 150016924 Common - transcriptional regulator, LysR family Cbei_2054 186 COG0583 LysR, Transcriptional regulator Transcription 150017759 Common - D-galactose-binding periplasmic protein precursor Cbei_2914 58 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018756 Nonpathogen - hypothetical protein Cbei_3944 1 None None None 150015377 Common - NLP/P60 protein Cbei_0487 142 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150015621 Common - alpha amylase, catalytic region Cbei_0735 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150018349 Common - methyl-accepting chemotaxis sensory transducer Cbei_3524 176 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018933 Common - Cyclopropane-fatty-acyl-phospholipid synthase Cbei_4121 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 150019388 Common - 3-deoxy-7-phosphoheptulonate synthase Cbei_4577 187 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150018492 Common - dual specificity protein phosphatase Cbei_3672 9 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 150018840 Common - amino acid permease-associated region Cbei_4028 179 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150018381 Common - TROVE domain protein Cbei_3557 16 None None None 150016436 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_1560 194 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150018955 Common - deoxyribose-phosphate aldolase Cbei_4143 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 150015612 Common - putative transcriptional regulator, MerR family Cbei_0726 78 COG0789 SoxR, Predicted transcriptional regulators Transcription 150015849 Common - PTS system fructose subfamily IIA component Cbei_0963 80 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150015942 Common - amidophosphoribosyltransferase Cbei_1056 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 150018179 Common - coenzyme A transferase Cbei_3351 103 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 150017593 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_2740 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 150018834 Common - glycoside hydrolase, family 3 domain protein Cbei_4022 128 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150019386 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Cbei_4575 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 150016585 Common - Peptidase S55, sporulation stage IV, protein B Cbei_1711 17 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150016830 Common - hypothetical protein Cbei_1958 14 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150019691 Common - DEAD_2 domain protein Cbei_4883 93 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 150019810 Common - phage integrase family protein Cbei_5002 174 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150019591 Common - helicase, putative Cbei_4782 69 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 150017987 Common - DEAD/DEAH box helicase domain protein Cbei_3152 225 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 150017543 Common - GCN5-related N-acetyltransferase Cbei_2688 7 COG0456 RimI, Acetyltransferases General function prediction only 150017956 Common - amino acid permease-associated region Cbei_3118 95 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150017486 Nonpathogen - hypothetical protein Cbei_2630 1 None None None 150016748 Common scpA segregation and condensation protein A Cbei_1875 137 COG1354 COG1354, Uncharacterized conserved protein Function unknown 150018641 Common - methyl-accepting chemotaxis sensory transducer Cbei_3823 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016984 Common - DNA mismatch repair protein MutS domain protein Cbei_2115 206 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150019522 Common - NAD-dependent epimerase/dehydratase Cbei_4712 235 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150017305 Common - hypothetical protein Cbei_2445 4 None None None 150019304 Common - hypothetical protein Cbei_4493 1 None None None 150015414 Common - transcriptional antiterminator, BglG Cbei_0524 31 COG3711 BglG, Transcriptional antiterminator Transcription 150018453 Common - transcriptional regulator, LysR family Cbei_3631 193 COG0583 LysR, Transcriptional regulator Transcription 150018900 Common - amino acid permease Cbei_4088 46 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150018923 Common - NADH dehydrogenase (quinone) Cbei_4111 180 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150019025 Common - type IV pilus assembly protein PilO Cbei_4213 2 None None None 150019556 Common - glycosyl transferase, family 2 Cbei_4747 191 COG5610 COG5610, Predicted hydrolase (HAD superfamily) General function prediction only 150019265 Common - putative transaldolase Cbei_4454 171 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150018997 Common - metal dependent phosphohydrolase Cbei_4185 119 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150018943 Nonpathogen - hypothetical protein Cbei_4131 1 None None None 150017928 Common - ABC transporter related Cbei_3089 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150018097 Nonpathogen - hypothetical protein Cbei_3266 2 None None None 150016476 Common - Diaminopimelate epimerase Cbei_1600 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 150019192 Nonpathogen - hypothetical protein Cbei_4381 1 None None None 150015053 Common rplN 50S ribosomal protein L14 Cbei_0161 246 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 150019181 Common - hypothetical protein Cbei_4369 18 None None None 150017493 Nonpathogen - hypothetical protein Cbei_2637 1 None None None 150016308 Common - methyl-accepting chemotaxis sensory transducer Cbei_1428 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018092 Common - permease Cbei_3261 81 COG0701 COG0701, Predicted permeases General function prediction only 150017154 Common - restriction endonuclease Cbei_2292 47 COG1715 Mrr, Restriction endonuclease Defense mechanisms 150016776 Common - fructose-1,6-bisphosphate aldolase, class II Cbei_1903 180 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 150018141 Nonpathogen - hypothetical protein Cbei_3312 1 None None None 150018940 Common - dihydrodipicolinate synthetase Cbei_4128 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150016796 Common - aspartate aminotransferase Cbei_1924 120 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150015581 Common - RNA-directed DNA polymerase Cbei_0694 88 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150019361 Common - PfkB domain protein Cbei_4550 174 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150015352 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Cbei_0462 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 150019776 Common - ABC transporter related Cbei_4968 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150018510 Nonpathogen - protein of unknown function DUF214 Cbei_3691 1 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150019783 Common - helix-turn-helix- domain containing protein, AraC type Cbei_4975 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016386 Common - hypothetical protein Cbei_1508 3 None None None 150015223 Nonpathogen - hypothetical protein Cbei_0333 1 None None None 150018336 Common - peptide deformylase Cbei_3511 180 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 150016731 Common - degV family protein Cbei_1858 56 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150016914 Common - hypothetical protein Cbei_2044 22 COG4895 COG4895, Uncharacterized conserved protein Function unknown 150018568 Common - transcriptional regulator, XRE family Cbei_3749 26 COG1396 HipB, Predicted transcriptional regulators Transcription 150015813 Nonpathogen - hypothetical protein Cbei_0927 1 None None None 150017507 Common - protein of unknown function DUF214 Cbei_2652 37 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 150018472 Common - major facilitator superfamily MFS_1 Cbei_3651 87 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150016993 Common - hypothetical protein Cbei_2124 9 None None None 150017196 Common - nitroreductase Cbei_2334 35 COG0778 NfnB, Nitroreductase Energy production and conversion 150018044 Nonpathogen - hypothetical protein Cbei_3212 1 None None None 150017580 Common - putative signal transduction protein Cbei_2727 202 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 150015342 Common - L-rhamnose 1-epimerase Cbei_0452 35 COG3254 COG3254, Uncharacterized conserved protein Function unknown 150015708 Common - germination protease Cbei_0822 15 None None None 150018880 Common - protein of unknown function DUF124 Cbei_4068 19 COG2013 COG2013, Uncharacterized conserved protein Function unknown 150018845 Nonpathogen - hypothetical protein Cbei_4033 1 None None None 150019394 Common - ABC transporter related Cbei_4584 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150015222 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Cbei_0332 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 150017850 Common - (NiFe) hydrogenase maturation protein HypF Cbei_3009 112 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 150016116 Common - Beta-galactosidase Cbei_1232 41 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 150019602 Common - transposase related protein (20) Cbei_4793 57 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 150018279 Nonpathogen - hypothetical protein Cbei_3452 1 None None None 150017650 Common - Phosphoglycerate mutase Cbei_2798 152 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150015897 Common - formate acetyltransferase Cbei_1011 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150018020 Nonpathogen - hypothetical protein Cbei_3188 1 None None None 150016428 Common - domain of unknown function DUF1745 Cbei_1552 35 COG3287 COG3287, Uncharacterized conserved protein Function unknown 150015128 Common - efflux transporter, RND family, MFP subunit Cbei_0236 118 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150016101 Common - hypothetical protein Cbei_1217 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150016869 Nonpathogen - hypothetical protein Cbei_1997 7 None None None 150017264 Common - TPR repeat-containing protein Cbei_2404 23 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 150014936 Nonpathogen - hypothetical protein Cbei_0044 7 COG3815 COG3815, Predicted membrane protein Function unknown 150019040 Common - hypoxanthine phosphoribosyltransferase Cbei_4228 149 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 150016121 Common - S-ribosylhomocysteinase Cbei_1237 54 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 150018571 Common - Carboxymuconolactone decarboxylase Cbei_3752 2 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 150015980 Common - recombination factor protein RarA Cbei_1096 244 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 150019357 Common - Xylose isomerase domain protein TIM barrel Cbei_4546 77 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 150019837 Common - DEAD/DEAH box helicase domain protein Cbei_5029 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150017170 Common - hypothetical protein Cbei_2308 1 None None None 150018825 Common - putative transcriptional regulator, GntR family Cbei_4013 218 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150019088 Common - protein of unknown function DUF115 Cbei_4276 22 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 150017595 Common - transaldolase Cbei_2742 90 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150015975 Common - AMP-dependent synthetase and ligase Cbei_1090 205 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150018063 Common - Methyltransferase type 11 Cbei_3232 24 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150018226 Common - phage-like element pbsx protein XkdK Cbei_3398 6 None None None 150015848 Common - sigma-54 factor, interaction domain-containing protein Cbei_0962 162 COG3933 COG3933, Transcriptional antiterminator Transcription 150019862 Common - carbon-monoxide dehydrogenase, catalytic subunit Cbei_5054 26 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150019119 Common - CheA signal transduction histidine kinase Cbei_4307 157 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 150015387 Common - septum site-determining protein MinD Cbei_0497 171 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 150019454 Common - transketolase Cbei_4644 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 150018125 Common - hypothetical protein Cbei_3296 12 COG3815 COG3815, Predicted membrane protein Function unknown 150015384 Common - penicillin-binding protein, transpeptidase Cbei_0494 193 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150019336 Common - glycoside hydrolase, family 1 Cbei_4525 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150017859 Common - beta-lactamase domain protein Cbei_3018 85 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150015187 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Cbei_0297 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 150019806 Common - ATPase-like protein Cbei_4998 13 COG3378 COG3378, Predicted ATPase General function prediction only 150015327 Common - peptidase M50 Cbei_0437 60 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 150019015 Common - glutamate synthase, NADH/NADPH, small subunit Cbei_4203 193 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150016358 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_1478 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150016132 Common - thioesterase domain, putative Cbei_1249 35 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 150017257 Common - Membrane dipeptidase Cbei_2397 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 150018304 Nonpathogen - hypothetical protein Cbei_3478 1 None None None 150016043 Common - putative methyltransferase Cbei_1159 206 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 150016934 Common - transcriptional regulator, TetR family Cbei_2064 58 COG1309 AcrR, Transcriptional regulator Transcription 150017299 Common - cytochrome b5 Cbei_2439 7 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 150019415 Common - Aldose 1-epimerase Cbei_4605 44 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 150019463 Common - Alpha-glucosidase Cbei_4653 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 150015381 Common - cell shape determining protein, MreB/Mrl family Cbei_0491 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 150018836 Common - protein of unknown function DUF6, transmembrane Cbei_4024 88 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150016339 Nonpathogen - methyl-accepting chemotaxis sensory transducer Cbei_1459 1 None None None 150018928 Common - hypothetical protein Cbei_4116 3 None None None 150017892 Common - integral membrane sensor signal transduction histidine kinase Cbei_3052 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016021 Common - hypothetical protein Cbei_1137 1 None None None 150016536 Nonpathogen - hypothetical protein Cbei_1660 1 None None None 150018691 Common - sigma-54 factor, interaction domain-containing protein Cbei_3875 156 COG3933 COG3933, Transcriptional antiterminator Transcription 150019366 Common - sigma-54 factor, interaction domain-containing protein Cbei_4555 156 COG3933 COG3933, Transcriptional antiterminator Transcription 150018053 Common - transcriptional regulator, LysR family Cbei_3221 191 COG0583 LysR, Transcriptional regulator Transcription 150016613 Common - protein of unknown function DUF328 Cbei_1739 78 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 150016755 Common - hypothetical protein Cbei_1882 3 None None None 150017536 Common - thioredoxin reductase Cbei_2681 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150015485 Common - transcriptional regulator, DeoR family Cbei_0596 43 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 150018543 Common - 2,5-didehydrogluconate reductase Cbei_3724 179 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 150019318 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_4507 171 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150015657 Common - binding-protein-dependent transport systems inner membrane component Cbei_0771 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150015928 Nonpathogen - hypothetical protein Cbei_1042 1 None None None 150014967 Common - phosphoserine aminotransferase Cbei_0075 124 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 150017682 Common - glycoside hydrolase, family 1 Cbei_2832 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150016575 Common - NusB antitermination factor Cbei_1701 196 COG0781 NusB, Transcription termination factor Transcription 150017107 Common - Cupin 2, conserved barrel domain protein Cbei_2241 22 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150016326 Common - Na+/H+ antiporter NhaA Cbei_1446 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 150017865 Common - Sulfite reductase (ferredoxin) Cbei_3024 174 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 150019907 Common trmE tRNA modification GTPase TrmE Cbei_5099 221 COG0486 ThdF, Predicted GTPase General function prediction only 150016154 Common - cobyric acid synthase CobQ Cbei_1272 154 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 150019323 Common - phosphoribulokinase/uridine kinase Cbei_4512 146 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 150019700 Common - hypothetical protein Cbei_4892 1 None None None 150016270 Common - Sporulation stage V, protein B Cbei_1389 39 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150019071 Common - flagellar FlbD family protein Cbei_4259 25 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 150018001 Nonpathogen - hypothetical protein Cbei_3167 1 None None None 150018914 Common - integral membrane sensor signal transduction histidine kinase Cbei_4102 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016879 Common - Radical SAM domain protein Cbei_2007 166 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150016083 Common nusA transcription elongation factor NusA Cbei_1199 235 COG0195 NusA, Transcription elongation factor Transcription 150018605 Common - integral membrane sensor signal transduction histidine kinase Cbei_3786 46 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150018689 Common - PTS system, mannose/fructose/sorbose family, IIB subunit Cbei_3873 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150015529 Common - hypothetical protein Cbei_0640 10 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 150018376 Common - hypothetical protein Cbei_3552 5 None None None 150018069 Common - alpha/beta hydrolase fold Cbei_3238 145 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150015614 Common - Methyltransferase type 11 Cbei_0728 42 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150015570 Nonpathogen - hypothetical protein Cbei_0682 1 None None None 150018123 Common - hypothetical protein Cbei_3294 1 None None None 150017841 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_3000 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 150018867 Common - Ethanolamine utilization protein EutN/carboxysome structural protein Ccml Cbei_4055 35 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150019911 Common rnpA ribonuclease P Cbei_5103 53 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 150016378 Common - transcriptional regulator, PadR-like family Cbei_1500 12 COG1695 COG1695, Predicted transcriptional regulators Transcription 150018446 Nonpathogen - hypothetical protein Cbei_3624 1 None None None 150015379 Common - Maf-like protein Cbei_0489 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 150018463 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Cbei_3642 112 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150018265 Common - Maltose O-acetyltransferase Cbei_3438 90 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150015867 Common - SMC domain protein Cbei_0981 130 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150018143 Common - diguanylate cyclase Cbei_3314 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150015303 Nonpathogen - ATP synthase F0, C subunit Cbei_0413 2 None None None 150017524 Common - ABC transporter related Cbei_2669 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150016185 Common - hypothetical protein Cbei_1303 11 None None None 150015375 Common - pyruvate kinase Cbei_0485 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 150017354 Common - CutC family protein Cbei_2496 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 150018517 Common - transcriptional regulator, MarR family Cbei_3698 8 COG1846 MarR, Transcriptional regulators Transcription 150019215 Common - heat shock protein DnaJ domain protein Cbei_4404 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150016180 Nonpathogen - hypothetical protein Cbei_1298 1 None None None 150019346 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_4535 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150016719 Common - Hemerythrin HHE cation binding domain protein Cbei_1846 22 COG3945 COG3945, Uncharacterized conserved protein Function unknown 150016823 Common - hypothetical protein Cbei_1951 6 COG2339 COG2339, Predicted membrane protein Function unknown 150016636 Common - Extracellular ligand-binding receptor Cbei_1762 147 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 150015140 Common - Oleoyl-(acyl-carrier-protein) hydrolase Cbei_0248 49 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 150016139 Common - helix-turn-helix domain protein Cbei_1256 121 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150017552 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_2698 13 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 150018966 Common - Orn/Lys/Arg decarboxylase, major region Cbei_4154 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 150017962 Common - basic membrane lipoprotein Cbei_3124 81 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 150017173 Common cbiC precorrin-8X methylmutase Cbei_2311 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 150016874 Common - nitrogenase molybdenum-iron protein alpha chain Cbei_2002 63 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150017905 Common - GCN5-related N-acetyltransferase Cbei_3065 19 COG0456 RimI, Acetyltransferases General function prediction only 150018428 Common - GCN5-related N-acetyltransferase Cbei_3606 16 COG0456 RimI, Acetyltransferases General function prediction only 150016302 Common - hypothetical protein Cbei_1422 5 None None None 150016608 Common - hypothetical protein Cbei_1734 1 None None None 150017726 Common - hypothetical protein Cbei_2878 1 None None None 150016084 Common - protein of unknown function DUF448 Cbei_1200 44 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 150019403 Nonpathogen - hypothetical protein Cbei_4593 1 None None None 150019587 Common - hypothetical protein Cbei_4778 2 None None None 150019410 Common - ATPase associated with various cellular activities, AAA_5 Cbei_4600 35 COG0714 COG0714, MoxR-like ATPases General function prediction only 150019193 Nonpathogen - hypothetical protein Cbei_4382 2 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 150015857 Common - transcriptional repressor, CopY family Cbei_0971 29 COG3682 COG3682, Predicted transcriptional regulator Transcription 150016357 Common - Beta-glucosidase Cbei_1477 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150016044 Common - pantetheine-phosphate adenylyltransferase Cbei_1160 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 150016236 Nonpathogen - hypothetical protein Cbei_1354 1 None None None 150018116 Nonpathogen - hypothetical protein Cbei_3286 1 None None None 150016698 Common - heat shock protein DnaJ domain protein Cbei_1825 2 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150016319 Common - regulatory protein, LacI Cbei_1439 127 COG1609 PurR, Transcriptional regulators Transcription 150018622 Common - molybdenum cofactor synthesis domain Cbei_3803 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 150015430 Common - sigma-54 factor, interaction domain-containing protein Cbei_0540 161 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 150015007 Common - DNA polymerase III subunit delta' Cbei_0115 243 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 150016100 Common - recA protein Cbei_1216 228 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 150018678 Common - transcriptional regulator, TetR family Cbei_3861 99 COG1309 AcrR, Transcriptional regulator Transcription 150016556 Common - type II secretion system protein Cbei_1682 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 150019845 Common - dihydrodipicolinate synthase Cbei_5037 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150019856 Common - hypothetical protein Cbei_5048 1 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 150017468 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Cbei_2610 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 150015462 Common - putative lipid kinase Cbei_0573 117 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 150018322 Common - ROK family protein Cbei_3497 35 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150017659 Common - Domain of unknown function DUF1863 Cbei_2807 2 None None None 150017254 Common - ABC transporter related Cbei_2394 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150015494 Common - binding-protein-dependent transport systems inner membrane component Cbei_0605 173 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150016143 Common - Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase Cbei_1261 71 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 150018278 Common - transposase related protein (20) Cbei_3451 57 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 150017692 Common - hypothetical protein Cbei_2842 13 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 150016654 Common - aminotransferase, class I and II Cbei_1781 228 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 150016469 Common - OmpA/MotB domain protein Cbei_1593 155 COG1360 MotB, Flagellar motor protein Cell motility and secretion 150019178 Common - polyA polymerase related protein (HD hydrolase) and P-loop ATP-ase domain Cbei_4366 17 COG4639 COG4639, Predicted kinase General function prediction only 150017975 Common - transcriptional regulator, HxlR family Cbei_3137 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 150016841 Common - carbamate kinase Cbei_1969 93 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 150018310 Common - NADPH-dependent FMN reductase Cbei_3484 52 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150016486 Common - hypothetical protein Cbei_1610 2 None None None 150017001 Common - Ankyrin Cbei_2132 43 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 150017559 Common - aminotransferase, class I and II Cbei_2705 211 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 150015249 Common - Methyltransferase type 12 Cbei_0359 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150015800 Common - hypothetical protein Cbei_0914 2 None None None 150019637 Common - methyl-accepting chemotaxis sensory transducer Cbei_4828 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016682 Common - protein of unknown function DUF214 Cbei_1809 155 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 150019596 Common - diaminopimelate decarboxylase Cbei_4787 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 150016299 Common - MATE efflux family protein Cbei_1419 181 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150017099 Common - serine dehydratase alpha chain Cbei_2232 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 150017632 Common - DEAD/DEAH box helicase domain protein Cbei_2779 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150014952 Common - hypothetical protein Cbei_0060 3 None None None 150018813 Common - helix-turn-helix- domain containing protein, AraC type Cbei_4001 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150017442 Nonpathogen - hypothetical protein Cbei_2584 1 None None None 150015469 Common - endonuclease III Cbei_0580 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 150016055 Common - Radical SAM domain protein Cbei_1171 109 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 150017673 Nonpathogen - hypothetical protein Cbei_2822 1 None None None 150019423 Nonpathogen - hypothetical protein Cbei_4613 1 None None None 150014912 Common - HAD-superfamily hydrolase, subfamily IIB Cbei_0020 70 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150018864 Common - signal transduction histidine kinase, LytS Cbei_4052 103 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150015426 Common - MATE efflux family protein Cbei_0536 136 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150017213 Common - hypothetical protein Cbei_2351 40 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 150016795 Common - major facilitator superfamily MFS_1 Cbei_1923 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018559 Common - transcriptional regulator, MarR family Cbei_3740 27 COG1846 MarR, Transcriptional regulators Transcription 150016449 Common pheS phenylalanyl-tRNA synthetase subunit alpha Cbei_1573 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 150018554 Nonpathogen - transcriptional regulator, XRE family Cbei_3735 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 150018210 Common - hypothetical protein Cbei_3382 2 None None None 150015727 Common - putative stage IV sporulation YqfD Cbei_0841 15 None None None 150016007 Common - hypothetical protein Cbei_1123 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 150016745 Nonpathogen - hypothetical protein Cbei_1872 1 None None None 150019788 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_4980 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150017764 Common - two component transcriptional regulator, winged helix family Cbei_2919 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016505 Common - hypothetical protein Cbei_1629 1 None None None 150019096 Common - protein of unknown function DUF115 Cbei_4284 19 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 150016157 Common - Cof-like hydrolase Cbei_1275 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150016643 Common - diguanylate cyclase Cbei_1769 184 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150018272 Common - small multidrug resistance protein Cbei_3445 145 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 150017573 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_2720 14 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150016218 Common - ferric uptake regulator, Fur family Cbei_1336 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150016750 Common - Sporulation protein YtfJ Cbei_1877 16 COG3874 COG3874, Uncharacterized conserved protein Function unknown 150015903 Common - hypothetical protein Cbei_1017 3 None None None 150015284 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Cbei_0394 198 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 150018595 Common - glycosyl transferase, family 39 Cbei_3776 16 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 150017070 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Cbei_2201 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 150014941 Common - MATE efflux family protein Cbei_0049 109 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150015631 Common - hypothetical protein Cbei_0745 6 None None None 150016394 Common - ABC transporter related Cbei_1516 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150016215 Nonpathogen - hypothetical protein Cbei_1333 1 None None None 150015522 Common - ribonuclease R Cbei_0633 200 COG0557 VacB, Exoribonuclease R Transcription 150015749 Common - Alanine racemase Cbei_0863 127 COG1609 PurR, Transcriptional regulators Transcription 150015265 Common - lipolytic protein, G-D-S-L family Cbei_0375 31 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150017289 Nonpathogen - hypothetical protein Cbei_2429 1 None None None 150015135 Common - transcriptional antiterminator, BglG Cbei_0243 32 COG3711 BglG, Transcriptional antiterminator Transcription 150019517 Common - glycosyl transferase, family 2 Cbei_4707 86 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150019766 Common - CheC domain protein Cbei_4958 9 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 150015939 Common - phosphoribosylformylglycinamidine synthase Cbei_1053 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 150019661 Common dnaE DNA polymerase III DnaE Cbei_4853 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 150019733 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_4925 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015061 Common rpmD 50S ribosomal protein L30 Cbei_0169 130 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 150016784 Nonpathogen - hypothetical protein Cbei_1912 1 None None None 150018950 Common - alpha/beta hydrolase fold Cbei_4138 94 COG2267 PldB, Lysophospholipase Lipid metabolism 150018358 Common - transcriptional regulator, DeoR family Cbei_3534 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150014974 Common - ribose-phosphate pyrophosphokinase Cbei_0082 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 150015714 Common hrcA heat-inducible transcription repressor Cbei_0828 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 150018014 Common - alpha/beta superfamily-like hydrolase Cbei_3182 79 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 150018534 Common - hypothetical protein Cbei_3715 5 None None None 150016528 Common - SH3, type 3 domain protein Cbei_1652 7 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 150014960 Common - anaerobic ribonucleoside triphosphate reductase Cbei_0068 110 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 150018456 Common - putative transcriptional regulator, MerR family Cbei_3634 56 COG0789 SoxR, Predicted transcriptional regulators Transcription 150016783 Nonpathogen - hypothetical protein Cbei_1911 1 None None None 150017461 Nonpathogen - Collagen triple helix repeat Cbei_2603 2 None None None 150015743 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_0857 7 None None None 150017474 Nonpathogen - hypothetical protein Cbei_2618 1 None None None 150017346 Common - SEC-C motif domain protein Cbei_2487 6 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 150016038 Common - thiamine pyrophosphokinase Cbei_1154 52 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 150015019 Common - protein of unknown function DUF147 Cbei_0127 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 150015685 Common - hypothetical protein Cbei_0799 1 None None None 150018711 Common - NADPH-dependent FMN reductase Cbei_3895 43 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150019005 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Cbei_4193 94 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 150015196 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cbei_0306 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150016019 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Cbei_1135 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 150018443 Common - hypothetical protein Cbei_3621 1 None None None 150017940 Common - hypothetical protein Cbei_3101 3 None None None 150016491 Common - helix-turn-helix domain protein Cbei_1615 51 COG1395 COG1395, Predicted transcriptional regulator Transcription 150016037 Common - ribulose-phosphate 3-epimerase Cbei_1153 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150016691 Common - permease Cbei_1818 60 COG0701 COG0701, Predicted permeases General function prediction only 150019378 Common - ROK family protein Cbei_4567 169 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150016972 Common - acetyl-CoA hydrolase/transferase Cbei_2103 102 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 150015782 Nonpathogen - hypothetical protein Cbei_0896 1 None None None 150016497 Common - RecT protein Cbei_1621 9 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 150017933 Common - ABC transporter related Cbei_3094 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150016286 Common - hypothetical protein Cbei_1406 1 None None None 150017317 Common - Alanine racemase Cbei_2457 128 COG1609 PurR, Transcriptional regulators Transcription 150018766 Common - putative CheW protein Cbei_3954 135 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150016498 Common - beta-lactamase domain protein Cbei_1622 49 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 150016010 Common - multi-sensor signal transduction histidine kinase Cbei_1126 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150015253 Nonpathogen - hypothetical protein Cbei_0363 1 None None None 150017715 Common - transcriptional regulator, TetR family Cbei_2866 25 COG1309 AcrR, Transcriptional regulator Transcription 150019183 Common - hypothetical protein Cbei_4371 5 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 150017454 Common - WxcM domain protein, C-terminal domain protein Cbei_2596 24 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 150017795 Common - hypothetical protein Cbei_2952 3 COG3462 COG3462, Predicted membrane protein Function unknown 150015994 Common - GTP-binding protein TypA Cbei_1110 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 150018075 Common aspA aspartate ammonia-lyase Cbei_3244 226 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 150019727 Common - nitroreductase Cbei_4919 45 COG0778 NfnB, Nitroreductase Energy production and conversion 150019207 Nonpathogen - hypothetical protein Cbei_4396 1 None None None 150016419 Common - D-tyrosyl-tRNA deacylase Cbei_1541 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 150017122 Common - hypothetical protein Cbei_2257 1 None None None 150017564 Common - peptidase M42 family protein Cbei_2710 86 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 150019163 Common - ABC transporter related Cbei_4351 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150015833 Common - protein of unknown function DUF523 Cbei_0947 52 COG1683 COG1683, Uncharacterized conserved protein Function unknown 150018297 Common - domain of unknown function DUF1745 Cbei_3470 39 COG3287 COG3287, Uncharacterized conserved protein Function unknown 150019035 Common - protein of unknown function UPF0029 Cbei_4223 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 150015644 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_0758 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150019132 Common murG N-acetylglucosaminyl transferase Cbei_4320 213 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150015930 Common - NAD+ synthetase Cbei_1044 185 COG0171 NadE, NAD synthase Coenzyme metabolism 150015012 Common - transcriptional repressor, CtsR Cbei_0120 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 150016837 Common - ABC transporter related Cbei_1965 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 150017146 Common - flavodoxin Cbei_2283 38 COG0716 FldA, Flavodoxins Energy production and conversion 150016380 Common - Carboxymuconolactone decarboxylase Cbei_1502 9 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 150018086 Common - hypothetical protein Cbei_3255 7 None None None 150017163 Common - hypothetical protein Cbei_2301 37 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150016312 Common - hypothetical protein Cbei_1432 21 COG4309 COG4309, Uncharacterized conserved protein Function unknown 150017900 Common - FAD dependent oxidoreductase Cbei_3060 85 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 150019701 Common - NAD-dependent deacetylase Cbei_4893 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 150016896 Common - DNA polymerase, beta domain protein region Cbei_2024 5 None None None 150018482 Common - integral membrane sensor signal transduction histidine kinase Cbei_3662 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150018498 Common - transposase-related protein Cbei_3678 3 None None None 150015023 Common cysS cysteinyl-tRNA synthetase Cbei_0131 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150016301 Common - hypothetical protein Cbei_1421 2 None None None 150017282 Common - peptidase U61, LD-carboxypeptidase A Cbei_2422 76 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 150015717 Common - chaperone protein DnaJ Cbei_0831 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150014931 Common - conserved hypothetical radical SAM protein Cbei_0039 72 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 150018506 Common - hypothetical protein Cbei_3686 15 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150017391 Common - NLP/P60 protein Cbei_2533 151 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150018256 Common - uncharacterized conserved protein, YbhB family Cbei_3428 9 COG1881 COG1881, Phospholipid-binding protein General function prediction only 150017950 Common - small acid-soluble spore protein, alpha/beta type Cbei_3111 11 None None None 150019610 Common - Heavy metal transport/detoxification protein Cbei_4801 7 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150017086 Common - hypothetical protein Cbei_2218 37 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150016155 Nonpathogen - hypothetical protein Cbei_1273 1 None None None 150016764 Common - tRNA adenylyltransferase Cbei_1891 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 150015465 Common - MgtE intracellular region Cbei_0576 181 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 150016826 Common - major facilitator superfamily MFS_1 Cbei_1954 149 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018908 Common - GntR domain protein Cbei_4096 138 COG2186 FadR, Transcriptional regulators Transcription 150017708 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Cbei_2859 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150016267 Common - amidohydrolase Cbei_1386 172 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150017649 Common - putative cell wall binding repeat-containing protein Cbei_2797 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018674 Common - alpha/beta hydrolase fold Cbei_3857 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150019056 Common - putative cell wall binding repeat-containing protein Cbei_4244 2 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016377 Common - hypothetical protein Cbei_1499 5 None None None 150015480 Common - glycoside hydrolase, family 25 Cbei_0591 22 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150016549 Nonpathogen - hypothetical protein Cbei_1674 2 None None None 150015696 Common - ATP-dependent protease Cbei_0810 163 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 150015729 Common - hypothetical protein Cbei_0843 113 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 150015362 Common - 2-nitropropane dioxygenase, NPD Cbei_0472 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 150017276 Common - tyrosyl-tRNA synthetase Cbei_2416 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150018635 Common - two component, sigma54 specific, transcriptional regulator, Fis family Cbei_3816 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150014927 Common - helix-turn-helix domain protein Cbei_0035 2 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150015085 Common - integral membrane sensor signal transduction histidine kinase Cbei_0193 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150018073 Common - hypothetical protein Cbei_3242 4 None None None 150015009 Common - metal-binding protein of ferredoxin fold Cbei_0117 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150017512 Common - transcriptional regulator, AraC family Cbei_2657 139 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016958 Common - ABC transporter related Cbei_2089 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150019822 Nonpathogen - hypothetical protein Cbei_5014 1 None None None 150015200 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Cbei_0310 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150018006 Nonpathogen - Resolvase helix-turn-helix domain protein Cbei_3172 1 None None None 150018585 Common - transcriptional regulator, AraC family Cbei_3766 107 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016400 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_1522 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150017825 Common - integral membrane sensor signal transduction histidine kinase Cbei_2984 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017746 Common - thioesterase superfamily protein Cbei_2899 36 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 150018613 Common - formate dehydrogenase accessory protein FdhD Cbei_3794 100 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 150016583 Common argR arginine repressor Cbei_1709 81 COG1438 ArgR, Arginine repressor Transcription 150015991 Common - protein of unknown function DUF1292 Cbei_1107 11 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 150019488 Common - binding-protein-dependent transport systems inner membrane component Cbei_4678 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150014996 Common - transcription elongation factor GreA Cbei_0104 204 COG0782 GreA, Transcription elongation factor Transcription 150018723 Common - galactoside O-acetyltransferase Cbei_3909 208 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150016539 Common - Ig domain protein, group 2 domain protein Cbei_1663 18 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 150018366 Common - binding-protein-dependent transport systems inner membrane component Cbei_3542 100 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 150017049 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Cbei_2180 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 150017801 Common - thioredoxin Cbei_2958 236 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150018778 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cbei_3966 31 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150019698 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Cbei_4890 153 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150016661 Common - hypothetical protein Cbei_1788 4 None None None 150018983 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_4171 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150017198 Common - protein of unknown function UPF0047 Cbei_2336 122 COG0432 COG0432, Uncharacterized conserved protein Function unknown 150016877 Common - nitrogenase cofactor biosynthesis protein NifB Cbei_2005 98 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150015586 Common - cryptic 6-phospho-beta-glucosidase Cbei_0700 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150017401 Common - HI0933 family protein Cbei_2543 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 150018646 Common - ThiJ/PfpI domain protein Cbei_3829 22 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 150017128 Common - helix-turn-helix domain protein Cbei_2265 4 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 150017010 Common - ABC transporter related Cbei_2141 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150018788 Nonpathogen - hypothetical protein Cbei_3976 1 None None None 150018964 Common - ATPase AAA-2 domain protein Cbei_4152 220 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150017911 Common - hypothetical protein Cbei_3072 7 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 150019634 Common - two component transcriptional regulator, LuxR family Cbei_4825 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150015555 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Cbei_0666 14 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 150017517 Common - cell wall hydrolase/autolysin Cbei_2662 150 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150019327 Common - argininosuccinate lyase Cbei_4516 235 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 150015549 Common - Accessory gene regulator B Cbei_0660 2 None None None 150016369 Common - hypothetical protein Cbei_1490 8 None None None 150019104 Common - flagellar protein FliS Cbei_4292 46 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 150019674 Common - carboxyl-terminal protease Cbei_4866 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150016361 Nonpathogen - hypothetical protein Cbei_1481 1 None None None 150019075 Common - flagellar hook-length control protein Cbei_4263 9 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 150018496 Common - hypothetical protein Cbei_3676 3 None None None 150017661 Common - Domain of unknown function DUF1863 Cbei_2809 14 None None None 150018790 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cbei_3978 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150017015 Common - polysaccharide deacetylase Cbei_2146 86 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150018405 Common - hypothetical protein Cbei_3581 1 None None None 150016982 Common - Domain of unknown function DUF1883 Cbei_2113 8 None None None 150015439 Common araD L-ribulose-5-phosphate 4-epimerase Cbei_0549 123 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 150017339 Common - hypothetical protein Cbei_2480 34 COG5496 COG5496, Predicted thioesterase General function prediction only 150018370 Common - conserved hypothetical protein CHP02464 Cbei_3546 24 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 150019640 Common - flagellar motor protein MotA Cbei_4831 80 COG1291 MotA, Flagellar motor component Cell motility and secretion 150015998 Common - penicillin-binding protein, transpeptidase Cbei_1114 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150018811 Common - protein of unknown function DUF218 Cbei_3999 10 COG1434 COG1434, Uncharacterized conserved protein Function unknown 150017183 Common - alpha,alpha-phosphotrehalase Cbei_2321 164 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150016440 Common - ABC transporter related Cbei_1564 242 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150018410 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3587 19 COG0716 FldA, Flavodoxins Energy production and conversion 150016808 Common - aminotransferase class-III Cbei_1936 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 150019297 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_4486 22 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016424 Common - hypothetical protein Cbei_1546 2 None None None 150016413 Common - membrane protein Cbei_1535 6 None None None 150019895 Common - protein of unknown function DUF951 Cbei_5087 26 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 150015594 Common - cobalamin B12-binding domain protein Cbei_0708 129 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 150017628 Common - NUDIX hydrolase Cbei_2775 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 150017256 Common - hypothetical protein Cbei_2396 4 None None None 150018799 Nonpathogen - hypothetical protein Cbei_3987 4 None None None 150017598 Nonpathogen - zinc finger, SWIM domain protein Cbei_2745 1 None None None 150016234 Nonpathogen - hypothetical protein Cbei_1352 2 None None None 150015602 Common - major facilitator superfamily MFS_1 Cbei_0716 70 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019882 Common - Adenylosuccinate synthase Cbei_5074 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 150016285 Common - protein of unknown function DUF1292 Cbei_1405 1 None None None 150015794 Common - phage prohead protease, HK97 family Cbei_0908 29 COG3740 COG3740, Phage head maturation protease General function prediction only 150015309 Common - ATP synthase F1, epsilon subunit Cbei_0419 8 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 150017854 Common - hydrogenase (NiFe) small subunit HydA Cbei_3013 78 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 150015090 Common - isoaspartyl dipeptidase Cbei_0198 23 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150015914 Common - putative transcriptional regulator, AsnC family Cbei_1028 107 COG1522 Lrp, Transcriptional regulators Transcription 150016912 Common - transcription activator, effector binding Cbei_2042 107 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 150018108 Common - class II aldolase/adducin family protein Cbei_3277 118 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 150019750 Common - nitrogen regulatory protein P-II Cbei_4942 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150017118 Nonpathogen - hypothetical protein Cbei_2253 1 None None None 150019649 Common - helix-turn-helix- domain containing protein, AraC type Cbei_4840 97 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016258 Common - UviB-like protein Cbei_1376 2 None None None 150018866 Common - aldehyde dehydrogenase Cbei_4054 167 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150016976 Common - protein of unknown function DUF218 Cbei_2107 8 COG1434 COG1434, Uncharacterized conserved protein Function unknown 150015442 Common - Peptidylprolyl isomerase Cbei_0553 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 150018233 Common - response regulator receiver sensor signal transduction histidine kinase Cbei_3405 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150018705 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_3889 26 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150019630 Common - methyl-accepting chemotaxis sensory transducer Cbei_4821 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017239 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_2377 104 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017330 Common - small acid-soluble spore protein, alpha/beta type Cbei_2470 6 None None None 150017875 Common - response regulator receiver protein Cbei_3034 6 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150017990 Common - uncharacterized small protein Cbei_3155 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 150016252 Common - phage portal protein, SPP1 Cbei_1370 6 None None None 150017880 Common - fructose-1,6-bisphosphate aldolase Cbei_3039 36 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 150019797 Nonpathogen - hypothetical protein Cbei_4989 1 None None None 150015028 Common - elongation factor Tu Cbei_0136 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 150015962 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Cbei_1076 221 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 150016963 Common - ABC transporter, transmembrane region Cbei_2094 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150017624 Common - methyl-accepting chemotaxis sensory transducer Cbei_2771 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016832 Common - 2-dehydropantoate 2-reductase Cbei_1960 73 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 150015550 Common - ferredoxin--NADP(+) reductase subunit alpha Cbei_0661 93 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150017057 Nonpathogen - hypothetical protein Cbei_2188 1 None None None 150019381 Common - 3-dehydroquinate dehydratase Cbei_4570 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 150018633 Common - Beta-glucosidase Cbei_3814 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150019047 Common - cellulose synthase subunit domain Cbei_4235 8 None None None 150016204 Common - imidazoleglycerol phosphate synthase, cyclase subunit Cbei_1322 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 150017028 Nonpathogen - hypothetical protein Cbei_2159 1 None None None 150015119 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Cbei_0227 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 150018893 Common - oligogalacturonide transporter Cbei_4081 70 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150015097 Common - metal dependent phosphohydrolase Cbei_0205 6 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150017848 Common - hydrogenase formation HypD protein Cbei_3007 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 150015511 Common - Cysteine synthase Cbei_0622 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150015114 Common - PTS system, galactitol-specific IIC subunit Cbei_0222 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 150015518 Common - Cystathionine gamma-synthase Cbei_0629 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150018340 Common - Chloramphenicol O-acetyltransferase Cbei_3515 145 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150017806 Common - ubiquinone/menaquinone biosynthesis methyltransferase Cbei_2963 223 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150019548 Common - UDP-glucose 6-dehydrogenase Cbei_4738 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 150017925 Common - TfoX, C-terminal domain protein Cbei_3086 12 None None None 150017020 Common - hypothetical protein Cbei_2151 7 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 150015350 Common - 2-deoxy-D-gluconate 3-dehydrogenase Cbei_0460 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150016627 Common - Phosphoribosylanthranilate isomerase Cbei_1753 188 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 150018745 Nonpathogen - hypothetical protein Cbei_3933 1 None None None 150017506 Common - ABC transporter related Cbei_2651 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150019607 Common - PfkB domain protein Cbei_4798 90 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150017984 Nonpathogen - hypothetical protein Cbei_3149 1 None None None 150018339 Nonpathogen - hypothetical protein Cbei_3514 11 None None None 150015340 Common - Xylose isomerase domain protein TIM barrel Cbei_0450 16 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 150015948 Common - transcriptional repressor, CopY family Cbei_1062 39 COG3682 COG3682, Predicted transcriptional regulator Transcription 150015214 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Cbei_0324 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150017757 Common - methyl-accepting chemotaxis sensory transducer Cbei_2912 170 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018039 Common - putative cell wall binding repeat-containing protein Cbei_3207 19 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015504 Common - binding-protein-dependent transport systems inner membrane component Cbei_0615 193 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150018754 Common - GCN5-related N-acetyltransferase Cbei_3942 57 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150015801 Common - phage-like element pbsx protein XkdM Cbei_0915 4 None None None 150017211 Nonpathogen - hypothetical protein Cbei_2349 1 None None None 150015648 Common - oxidoreductase domain protein Cbei_0762 167 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150016757 Nonpathogen - hypothetical protein Cbei_1884 1 None None None 150017209 Nonpathogen - hypothetical protein Cbei_2347 1 None None None 150016851 Common - putative endoribonuclease L-PSP Cbei_1979 189 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 150018513 Common - cobalt transport protein Cbei_3694 40 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150019223 Common - S-adenosylmethionine decarboxylase Cbei_4412 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 150018663 Nonpathogen - hypothetical protein Cbei_3846 1 None None None 150019023 Common - hypothetical protein Cbei_4211 6 None None None 150017834 Common - NADH dehydrogenase subunit D Cbei_2993 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 150018999 Common - sulfate adenylyltransferase, small subunit Cbei_4187 136 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 150017487 Nonpathogen - conserved hypothetical protein, CF-44 family Cbei_2631 1 None None None 150015483 Common - degV family protein Cbei_0594 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150015535 Common - hypothetical protein Cbei_0646 13 COG4684 COG4684, Predicted membrane protein Function unknown 150019662 Common - Stress responsive alpha-beta barrel domain protein Cbei_4854 11 None None None 150016925 Common - NADPH-dependent FMN reductase Cbei_2055 109 COG0431 COG0431, Predicted flavoprotein General function prediction only 150017426 Common - pentapeptide repeat protein Cbei_2568 33 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150015204 Nonpathogen - hypothetical protein Cbei_0314 1 None None None 150019159 Common - 4-aminobutyrate aminotransferase Cbei_4347 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 150015629 Common - FliB family protein Cbei_0743 6 None None None 150015443 Common - carbon starvation protein CstA Cbei_0554 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 150016315 Common - Heavy metal transport/detoxification protein Cbei_1435 88 COG4633 COG4633, Uncharacterized protein conserved in bacteria Function unknown 150015538 Common - PP-loop domain protein Cbei_0649 160 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 150019829 Nonpathogen - hypothetical protein Cbei_5021 1 None None None 150018842 Nonpathogen - hypothetical protein Cbei_4030 1 None None None 150016409 Common ruvB Holliday junction DNA helicase B Cbei_1531 228 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 150019036 Common - putative transcriptional regulator, GntR family Cbei_4224 205 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150014932 Common - 2-phosphosulfolactate phosphatase Cbei_0040 46 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 150017863 Common - methyl-accepting chemotaxis sensory transducer Cbei_3022 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016717 Common - PTS system, fructose subfamily, IIC subunit Cbei_1844 142 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 150019554 Common - NLP/P60 protein Cbei_4744 158 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150018383 Nonpathogen - transcriptional regulator-like protein Cbei_3559 2 COG2378 COG2378, Predicted transcriptional regulator Transcription 150017293 Nonpathogen - hypothetical protein Cbei_2433 1 None None None 150019306 Common - integral membrane sensor signal transduction histidine kinase Cbei_4495 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017066 Common - PTS system sorbose subfamily IIB component Cbei_2197 34 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150017268 Nonpathogen - hypothetical protein Cbei_2408 1 None None None 150018162 Common - binding-protein-dependent transport systems inner membrane component Cbei_3333 189 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150017568 Common - Antibiotic biosynthesis monooxygenase Cbei_2715 23 COG1359 COG1359, Uncharacterized conserved protein Function unknown 150015854 Common - polysaccharide biosynthesis protein Cbei_0968 20 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150018280 Common - transcription activator, effector binding Cbei_3453 97 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015579 Common - acyl-ACP thioesterase Cbei_0691 22 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 150019238 Common - putative galactoside ABC transporter Cbei_4427 71 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015940 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Cbei_1054 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 150018935 Common - heat shock protein Hsp20 Cbei_4123 144 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 150018925 Common alr alanine racemase Cbei_4113 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 150019650 Common - oxidoreductase domain protein Cbei_4841 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150018538 Common - Maltose O-acetyltransferase Cbei_3719 183 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150019900 Common - protein of unknown function DUF1256 Cbei_5092 14 None None None 150017480 Common - hypothetical protein Cbei_2624 23 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 150017549 Nonpathogen - hypothetical protein Cbei_2694 1 None None None 150015756 Common - hypothetical protein Cbei_0870 2 None None None 150015762 Common - sodium/proline symporter Cbei_0876 181 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 150019267 Common - regulatory protein GntR, HTH Cbei_4456 131 COG1609 PurR, Transcriptional regulators Transcription 150016844 Common - Guanine deaminase Cbei_1972 154 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 150015667 Common - putative transcriptional regulator, Crp/Fnr family Cbei_0781 105 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150019129 Common - hypothetical protein Cbei_4317 1 None None None 150019520 Nonpathogen - hypothetical protein Cbei_4710 4 None None None 150016086 Common infB translation initiation factor IF-2 Cbei_1202 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 150016946 Common - ribose-phosphate pyrophosphokinase Cbei_2076 180 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 150019257 Common - transcriptional regulator, AraC family Cbei_4446 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015850 Common - PTS system sorbose subfamily IIB component Cbei_0964 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150019786 Common - glycoside hydrolase, family 4 Cbei_4978 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150015001 Common - sugar transporter Cbei_0109 171 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150014911 Common - transcriptional regulator, TetR family Cbei_0019 144 COG1309 AcrR, Transcriptional regulator Transcription 150016741 Common - Glycine hydroxymethyltransferase Cbei_1868 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 150017204 Common aspA aspartate ammonia-lyase Cbei_2342 239 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 150015623 Common - peptidase U32 Cbei_0737 11 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150018387 Common - flavodoxin Cbei_3563 16 COG0716 FldA, Flavodoxins Energy production and conversion 150018355 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3531 23 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150017193 Common - Endonuclease/exonuclease/phosphatase Cbei_2331 26 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 150018388 Common - histidine kinase Cbei_3564 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015957 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Cbei_1071 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150017119 Nonpathogen - hypothetical protein Cbei_2254 1 None None None 150019083 Common flgB flagellar basal body rod protein FlgB Cbei_4271 43 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 150019819 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_5011 129 COG1609 PurR, Transcriptional regulators Transcription 150015338 Common - 2-deoxy-D-gluconate 3-dehydrogenase Cbei_0448 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150019499 Common - hypothetical protein Cbei_4689 6 None None None 150019121 Common - response regulator receiver modulated CheB methylesterase Cbei_4309 203 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 150015150 Common - transcriptional regulator, TetR family Cbei_0259 65 COG1309 AcrR, Transcriptional regulator Transcription 150018732 Common - lipolytic protein, G-D-S-L family Cbei_3918 16 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150019435 Common - two component transcriptional regulator, winged helix family Cbei_4625 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015281 Common - Peptidoglycan-binding LysM Cbei_0391 9 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 150016454 Common - stage V sporulation protein D Cbei_1578 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150016542 Common - glycoside hydrolase, family 25 Cbei_1666 40 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150017218 Common - protein of unknown function DUF624 Cbei_2356 6 COG5578 COG5578, Predicted integral membrane protein Function unknown 150019909 Common - putative inner membrane protein translocase component YidC Cbei_5101 209 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 150015701 Common - Sporulation stage V, protein AC Cbei_0815 15 None None None 150015735 Common - pyruvate phosphate dikinase Cbei_0849 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150019338 Common - amino acid permease-associated region Cbei_4527 129 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 150018461 Common - VanZ family protein Cbei_3639 2 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 150019688 Common - UDP-glucose 6-dehydrogenase Cbei_4880 205 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 150018680 Common - putative transcriptional regulator, MerR family Cbei_3863 42 COG0789 SoxR, Predicted transcriptional regulators Transcription 150016065 Common rbgA ribosomal biogenesis GTPase Cbei_1181 107 COG1161 COG1161, Predicted GTPases General function prediction only 150019568 Nonpathogen - O-antigen polymerase Cbei_4759 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 150018244 Common - Protein of unknown function DUF1963 Cbei_3416 10 COG3878 COG3878, Uncharacterized protein conserved in bacteria Function unknown 150017671 Common - elongation factor G, domain IV Cbei_2820 234 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150018526 Common - diguanylate cyclase Cbei_3707 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 150019407 Common - HesB-related (seleno)protein Cbei_4597 2 COG0316 IscA, Uncharacterized conserved protein Function unknown 150016681 Common - ABC transporter related Cbei_1808 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150017177 Common - cobalt-precorrin-2 C(20)-methyltransferase Cbei_2315 161 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 150015671 Common - Sulfite reductase, Subunit C Cbei_0785 115 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 150019721 Common - PTS system, mannose/fructose/sorbose family, IIB subunit Cbei_4913 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150017243 Common - ABC transporter related Cbei_2381 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150018989 Common - AzlC family protein Cbei_4177 101 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 150017234 Common - Carboxymuconolactone decarboxylase Cbei_2372 90 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 150018080 Common - SNARE associated Golgi protein Cbei_3249 165 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 150016260 Nonpathogen - hypothetical protein Cbei_1378 1 None None None 150015769 Common - hypothetical protein Cbei_0883 2 None None None 150014907 Common - ErfK/YbiS/YcfS/YnhG family protein Cbei_0015 10 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150015982 Common - aminotransferase, class V Cbei_1098 241 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 150015569 Common - Thioesterase Cbei_0681 44 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 150019747 Common - binding-protein-dependent transport systems inner membrane component Cbei_4939 216 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 150017724 Common - efflux transporter, RND family, MFP subunit Cbei_2876 172 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150017791 Nonpathogen - membrane-bound metal-dependent hydrolase Cbei_2948 7 None None None 150018315 Nonpathogen - hypothetical protein Cbei_3490 1 None None None 150016646 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_1772 198 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150017731 Common - acyl-CoA dehydrogenase domain protein Cbei_2883 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150018545 Nonpathogen - hypothetical protein Cbei_3726 1 None None None 150016932 Nonpathogen - hypothetical protein Cbei_2062 1 None None None 150018451 Common - uncharacterized Fe-S protein Cbei_3629 125 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150018439 Common - NAD-dependent epimerase/dehydratase Cbei_3617 93 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150016534 Common - phage-like element pbsx protein XkdT Cbei_1658 3 None None None 150016396 Common - thiamine biosynthesis protein ThiS Cbei_1518 25 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 150019461 Common - major facilitator superfamily MFS_1 Cbei_4651 152 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150016939 Common - manganese containing catalase Cbei_2069 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 150017587 Common - transcriptional regulator, HxlR family Cbei_2734 133 COG1733 COG1733, Predicted transcriptional regulators Transcription 150016872 Common - nitrogen regulatory protein P-II Cbei_2000 124 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150017713 Common - efflux transporter, RND family, MFP subunit Cbei_2864 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150017680 Common - glycoside hydrolase, family 18 Cbei_2830 41 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 150018423 Common - transcriptional regulator, TetR family Cbei_3601 41 COG1309 AcrR, Transcriptional regulator Transcription 150018693 Common - sucrose-6-phosphate hydrolase Cbei_3877 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 150018193 Common - cell cycle protein Cbei_3365 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150015269 Common - 2-alkenal reductase Cbei_0379 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 150019809 Common - phage integrase family protein Cbei_5001 124 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150018597 Common - glycosyl transferase, family 2 Cbei_3778 192 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150018172 Common - PTS system, mannose/fructose/sorbose family, IIA subunit Cbei_3344 89 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150017105 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_2238 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019738 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cbei_4930 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 150016027 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Cbei_1143 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 150016351 Common - transcriptional regulator, HxlR family Cbei_1471 154 COG1733 COG1733, Predicted transcriptional regulators Transcription 150016250 Common - phage tail tape measure protein, TP901 family Cbei_1368 117 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150016170 Common - glutamate-1-semialdehyde aminotransferase Cbei_1288 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 150016041 Common - Dak phosphatase Cbei_1157 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 150019325 Common - hypothetical protein Cbei_4514 1 None None None 150018420 Common - putative transcriptional regulator, MerR family Cbei_3598 71 COG0789 SoxR, Predicted transcriptional regulators Transcription 150017890 Common - response regulator receiver protein Cbei_3050 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150017785 Common - protein of unknown function DUF421 Cbei_2942 62 COG2323 COG2323, Predicted membrane protein Function unknown 150018260 Common - ABC transporter related Cbei_3433 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150018876 Common - microcompartments protein Cbei_4064 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 150018312 Common - methyl-accepting chemotaxis sensory transducer Cbei_3486 11 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018603 Nonpathogen - hypothetical protein Cbei_3784 3 None None None 150018851 Common - hypothetical protein Cbei_4039 2 None None None 150018713 Common - hypothetical protein Cbei_3897 1 None None None 150018953 Common - arsenate reductase and related Cbei_4141 30 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 150019308 Common - Antibiotic biosynthesis monooxygenase Cbei_4497 49 COG1359 COG1359, Uncharacterized conserved protein Function unknown 150018698 Common - hypothetical protein Cbei_3882 3 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150015816 Common - hypothetical protein Cbei_0930 1 None None None 150019195 Nonpathogen - hypothetical protein Cbei_4384 1 None None None 150015393 Common - S-layer domain protein domain Cbei_0503 11 None None None 150018267 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3440 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150017104 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_2237 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150019348 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_4537 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150018269 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3442 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150017185 Common - GCN5-related N-acetyltransferase Cbei_2323 8 COG0456 RimI, Acetyltransferases General function prediction only 150017434 Common - Cof-like hydrolase Cbei_2576 84 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150017259 Common - integral membrane sensor signal transduction histidine kinase Cbei_2399 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150019341 Common - helix-turn-helix- domain containing protein, AraC type Cbei_4530 63 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150016434 Nonpathogen - hypothetical protein Cbei_1558 1 None None None 150016862 Common moaC molybdenum cofactor biosynthesis protein C Cbei_1990 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 150019594 Common - signal peptidase I Cbei_4785 191 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150016046 Common - Sporulation integral membrane protein YlbJ Cbei_1162 14 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 150016606 Common - integral membrane sensor signal transduction histidine kinase Cbei_1732 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015373 Nonpathogen - hypothetical protein Cbei_0483 1 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 150016684 Common - SNARE associated Golgi protein Cbei_1811 4 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150015865 Common - hypothetical protein Cbei_0979 15 COG4720 COG4720, Predicted membrane protein Function unknown 150016113 Common - extracellular solute-binding protein, family 1 Cbei_1229 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017689 Common - methyl-accepting chemotaxis sensory transducer Cbei_2839 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019401 Common - two component transcriptional regulator, winged helix family Cbei_4591 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150019112 Common - anti-sigma-28 factor, FlgM Cbei_4300 1 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 150016818 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cbei_1946 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 150015855 Common - helix-turn-helix domain protein Cbei_0969 1 None None None 150016304 Common - serine/threonine kinase related protein Cbei_1424 2 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 150015142 Common - amino acid adenylation domain Cbei_0250 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150016126 Common - NLP/P60 protein Cbei_1242 129 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150018515 Common - hydrogenase accessory protein HypB Cbei_3696 159 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 150018062 Nonpathogen - hypothetical protein Cbei_3231 1 None None None 150015921 Common - hypothetical protein Cbei_1035 1 None None None 150019418 Common - hypothetical protein Cbei_4608 17 None None None 150017582 Common - Carboxymuconolactone decarboxylase Cbei_2729 90 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 150017959 Common - inner-membrane translocator Cbei_3121 140 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 150018588 Common - Cof-like hydrolase Cbei_3769 130 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150018562 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3743 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150018438 Common - transcriptional regulator, XRE family Cbei_3616 23 COG1396 HipB, Predicted transcriptional regulators Transcription 150015132 Common - Cystathionine gamma-synthase Cbei_0240 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150018869 Nonpathogen - hypothetical protein Cbei_4057 1 None None None 150018448 Common - hypothetical protein Cbei_3626 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150016948 Common - hypothetical protein Cbei_2078 23 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 150017161 Nonpathogen - hypothetical protein Cbei_2299 1 None None None 150018987 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cbei_4175 116 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150019753 Common - Endothelin-converting enzyme 1 Cbei_4945 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 150017059 Common - protein of unknown function DUF21 Cbei_2190 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150016118 Common - histidine kinase internal region Cbei_1234 110 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150019135 Common - DNA topoisomerase IV subunit A Cbei_4323 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 150016568 Common - Stage III sporulation AC family protein Cbei_1694 1 None None None 150015389 Common - cell cycle protein Cbei_0499 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150018139 Common - putative transcriptional regulator, MerR family Cbei_3310 60 COG0789 SoxR, Predicted transcriptional regulators Transcription 150015185 Common - hypothetical protein Cbei_0295 1 None None None 150015321 Common - ComF protein Cbei_0431 93 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 150018042 Common - transcriptional regulator, MarR family Cbei_3210 11 COG1846 MarR, Transcriptional regulators Transcription 150019668 Common - Peptidoglycan glycosyltransferase Cbei_4860 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150018090 Common - oxidoreductase domain protein Cbei_3259 152 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150017152 Nonpathogen - hypothetical protein Cbei_2290 2 None None None 150018938 Common - Alpha-N-arabinofuranosidase Cbei_4126 40 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 150019272 Common - ABC transporter related Cbei_4461 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150019190 Common - pentapeptide repeat protein Cbei_4379 66 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150015588 Common - transcriptional regulator, DeoR family Cbei_0702 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150016388 Common - dihydroxy-acid dehydratase Cbei_1510 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150017062 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cbei_2193 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 150018426 Common - hypothetical protein Cbei_3604 25 COG4898 COG4898, Uncharacterized protein conserved in bacteria Function unknown 150017143 Common - hydroxylamine reductase Cbei_2280 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150017982 Common - MATE efflux family protein Cbei_3145 112 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150015335 Common - rhamnulokinase Cbei_0445 94 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 150016249 Nonpathogen - hypothetical protein Cbei_1367 1 None None None 150018289 Common - Abortive infection protein Cbei_3462 24 None None None 150016456 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Cbei_1580 214 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150018402 Common - membrane protein; CF-9 family Cbei_3578 5 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 150019216 Nonpathogen - hypothetical protein Cbei_4405 1 None None None 150015225 Common - Glucitol operon activator Cbei_0335 12 COG4578 GutM, Glucitol operon activator Transcription 150015242 Common ligA NAD-dependent DNA ligase LigA Cbei_0352 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 150016320 Common - extracellular solute-binding protein, family 1 Cbei_1440 44 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017678 Common - glycoside hydrolase, family 16 Cbei_2828 60 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 150019576 Nonpathogen - hypothetical protein Cbei_4767 1 None None None 150016119 Common - response regulator receiver protein Cbei_1235 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150018058 Nonpathogen - hypothetical protein Cbei_3226 1 None None None 150017652 Common - MukB N-terminal domain/M protein repeat protein Cbei_2800 75 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 150015231 Common pgi glucose-6-phosphate isomerase Cbei_0341 192 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 150019029 Common - type II secretion system protein Cbei_4217 148 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 150019604 Common - hypothetical protein Cbei_4795 12 COG4905 COG4905, Predicted membrane protein Function unknown 150018288 Nonpathogen - hypothetical protein Cbei_3461 1 None None None 150015895 Common - formate acetyltransferase Cbei_1009 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150017810 Common - hypothetical protein Cbei_2967 2 None None None 150018334 Common - Radical SAM domain protein Cbei_3509 105 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 150016902 Common - Integrase, catalytic region Cbei_2031 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 150016421 Common - coproporphyrinogen III oxidase Cbei_1543 214 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150016162 Common - putative sodium-glucose/galactose cotransporter Cbei_1280 40 COG3647 COG3647, Predicted membrane protein Function unknown 150016899 Common - two component transcriptional regulator, winged helix family Cbei_2028 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017819 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Cbei_2977 202 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150017266 Common - hypothetical protein Cbei_2406 15 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150016561 Nonpathogen - hypothetical protein Cbei_1687 1 None None None 150018776 Common - CHAP domain containing protein Cbei_3964 5 COG3942 COG3942, Surface antigen General function prediction only 150016123 Common - oligopeptide transporter, OPT family Cbei_1239 39 COG1297 COG1297, Predicted membrane protein Function unknown 150015262 Common - sulfatase Cbei_0372 65 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 150017534 Nonpathogen - hypothetical protein Cbei_2679 7 COG1584 COG1584, Predicted membrane protein Function unknown 150018303 Common - hypothetical protein Cbei_3477 1 None None None 150018823 Common - hypothetical protein Cbei_4011 6 COG2128 COG2128, Uncharacterized conserved protein Function unknown 150018764 Common - protein of unknown function DUF81 Cbei_3952 38 COG0730 COG0730, Predicted permeases General function prediction only 150016073 Common tsf elongation factor Ts Cbei_1189 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 150019707 Common - VanZ family protein Cbei_4899 9 COG5652 COG5652, Predicted integral membrane protein Function unknown 150016226 Nonpathogen - hypothetical protein Cbei_1344 1 None None None 150017008 Common - transport system permease protein Cbei_2139 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150019355 Common - Enoyl-CoA hydratase/isomerase Cbei_4544 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150017776 Common - transcriptional regulator, TetR family Cbei_2931 27 COG1309 AcrR, Transcriptional regulator Transcription 150017852 Common - hydrogenase maturation protease Cbei_3011 4 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 150015786 Common - phage integrase family protein Cbei_0900 100 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150019835 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cbei_5027 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150015329 Common - RNA binding S1 domain protein Cbei_0439 224 COG2183 Tex, Transcriptional accessory protein Transcription 150019250 Common thiH thiamine biosynthesis protein ThiH Cbei_4439 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 150015497 Common - heavy metal transport/detoxification protein Cbei_0608 31 COG2836 COG2836, Uncharacterized conserved protein Function unknown 150018130 Common - transcriptional regulator, MarR family Cbei_3301 42 COG1846 MarR, Transcriptional regulators Transcription 150016778 Common - hypothetical protein Cbei_1905 14 None None None 150016328 Common - regulatory protein, ArsR Cbei_1448 182 COG0640 ArsR, Predicted transcriptional regulators Transcription 150016474 Common - transcriptional regulator, RpiR family Cbei_1598 89 COG1737 RpiR, Transcriptional regulators Transcription 150014896 Common recF recombination protein F Cbei_0004 155 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 150016798 Common - transcriptional regulator, PadR-like family Cbei_1926 46 COG1695 COG1695, Predicted transcriptional regulators Transcription 150015071 Common rpsD 30S ribosomal protein S4 Cbei_0179 228 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 150019099 Common - Integrase, catalytic region Cbei_4287 78 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 150017078 Nonpathogen - hypothetical protein Cbei_2209 1 None None None 150016330 Common - putative transcriptional regulator, Crp/Fnr family Cbei_1450 24 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150015792 Common - phage Terminase Cbei_0906 43 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 150017996 Common - N-6 DNA methylase Cbei_3161 152 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150016466 Common - protein of unknown function YGGT Cbei_1590 16 None None None 150015300 Common - UDP-N-acetylglucosamine 2-epimerase Cbei_0410 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 150015684 Common - tryptophanyl-tRNA synthetase Cbei_0798 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150015846 Common - PfkB domain protein Cbei_0960 58 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150015179 Common - hypothetical protein Cbei_0289 1 None None None 150019860 Nonpathogen - hypothetical protein Cbei_5052 1 None None None 150018016 Common - RNA-directed DNA polymerase (Reverse transcriptase) Cbei_3184 92 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150014972 Common - SpoVG family protein Cbei_0080 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 150015745 Common - peptidase C26 Cbei_0859 152 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 150018912 Common - secretion protein HlyD Cbei_4100 150 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150017693 Common - hypothetical protein Cbei_2843 6 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 150018504 Common - AAA ATPase Cbei_3684 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150016169 Common - delta-aminolevulinic acid dehydratase Cbei_1287 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 150015194 Common - small multidrug resistance protein Cbei_0304 106 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 150017180 Nonpathogen - hypothetical protein Cbei_2318 1 None None None 150016734 Common - MATE efflux family protein Cbei_1861 132 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150018742 Nonpathogen - hypothetical protein Cbei_3930 1 None None None 150017459 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Cbei_2601 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 150016012 Common - phosphate ABC transporter, inner membrane subunit PstC Cbei_1128 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 150015463 Nonpathogen - hypothetical protein Cbei_0574 1 None None None 150015829 Common - domain of unknown function DUF1727 Cbei_0943 49 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150019629 Common - response regulator receiver sensor signal transduction histidine kinase Cbei_4820 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016152 Common - putative cell wall binding repeat-containing protein Cbei_1270 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018806 Common - hypothetical protein Cbei_3994 1 None None None 150019512 Common - transcriptional regulator, RpiR family Cbei_4702 35 COG1737 RpiR, Transcriptional regulators Transcription 150015649 Common - transcriptional regulator, RpiR family Cbei_0763 86 COG1737 RpiR, Transcriptional regulators Transcription 150019189 Nonpathogen - hypothetical protein Cbei_4378 1 None None None 150015996 Common - O-methyltransferase, family 3 Cbei_1112 112 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 150019505 Common - Choline/ethanolamine kinase Cbei_4695 56 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 150019875 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_5067 55 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150017496 Nonpathogen - hypothetical protein Cbei_2640 1 None None None 150019712 Common - glucose-1-phosphate adenylyltransferase, GlgD subunit Cbei_4904 121 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 150016781 Nonpathogen - membrane -like protein Cbei_1909 1 COG4720 COG4720, Predicted membrane protein Function unknown 150019897 Common - hypothetical protein Cbei_5089 2 None None None 150016493 Common - hypothetical protein Cbei_1617 2 None None None 150018329 Common - response regulator receiver protein Cbei_3504 29 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150018910 Common - transcriptional regulator, MarR family Cbei_4098 42 COG1846 MarR, Transcriptional regulators Transcription 150016213 Common - GTPase EngB Cbei_1331 190 COG0218 COG0218, Predicted GTPase General function prediction only 150019869 Common - beta-lactamase domain protein Cbei_5061 69 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 150016035 Common - protein kinase Cbei_1151 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 150016288 Common - HPr kinase/phosphorylase Cbei_1408 78 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 150016442 Nonpathogen - hypothetical protein Cbei_1566 1 None None None 150016199 Common - Histidinol dehydrogenase Cbei_1317 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 150018067 Common - transposase, IS111A/IS1328/IS1533 Cbei_3236 27 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150015367 Common - periplasmic solute binding protein Cbei_0477 166 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150017452 Common - hypothetical protein Cbei_2594 153 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 150015775 Nonpathogen - hypothetical protein Cbei_0889 1 None None None 150019448 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_4638 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150015960 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Cbei_1074 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 150018659 Common - YCII-related Cbei_3842 37 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 150015654 Common - histidine kinase internal region Cbei_0768 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150019619 Common - Abortive infection protein Cbei_4810 52 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 150017571 Common - hypothetical protein Cbei_2718 5 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 150015719 Common trmB tRNA (guanine-N(7))-methyltransferase Cbei_0833 137 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 150017793 Common - integral membrane sensor signal transduction histidine kinase Cbei_2950 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019396 Common - Lantibiotic modifying -like protein Cbei_4586 17 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 150019003 Common - sulfate ABC transporter, inner membrane subunit CysW Cbei_4191 199 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 150015042 Common rpsJ 30S ribosomal protein S10 Cbei_0150 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 150018261 Common - cytidine deaminase Cbei_3434 111 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 150016771 Common - calcium/proton antiporter, CaCA family Cbei_1898 102 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 150015527 Common - lipoprotein, YaeC family Cbei_0638 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 150019529 Common - putative cell wall binding repeat-containing protein Cbei_4719 7 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016578 Common - Exonuclease VII, small subunit Cbei_1704 25 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 150015737 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Cbei_0851 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 150015127 Common - encapsulation protein CapA Cbei_0235 79 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 150017071 Common - ABC transporter related Cbei_2202 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150015014 Common - ATP:guanido phosphotransferase Cbei_0122 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 150016028 Common - primosome assembly protein PriA Cbei_1144 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 150017566 Common - FliB family protein Cbei_2712 7 None None None 150018320 Common - beta-lactamase domain protein Cbei_3495 26 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150015021 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Cbei_0129 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 150018219 Common - hypothetical protein Cbei_3391 6 None None None 150015063 Common secY preprotein translocase subunit SecY Cbei_0171 244 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 150018254 Common - hemerythrin-like metal-binding protein Cbei_3426 48 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150019018 Common - glutamine synthetase, type I Cbei_4206 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 150019854 Common - ABC transporter related Cbei_5046 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150016696 Common - methionine aminopeptidase, type I Cbei_1823 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 150019209 Nonpathogen - hypothetical protein Cbei_4398 1 None None None 150016202 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Cbei_1320 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 150017601 Common - ATPase associated with various cellular activities, AAA_5 Cbei_2748 48 COG0714 COG0714, MoxR-like ATPases General function prediction only 150015831 Common - peptidase U32 Cbei_0945 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150018484 Common - peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin Cbei_3664 40 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150019398 Common - major facilitator superfamily MFS_1 Cbei_4588 17 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150017722 Common - hypothetical protein Cbei_2874 1 None None None 150019781 Common - Alpha-N-arabinofuranosidase Cbei_4973 20 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 150015642 Common - ErfK/YbiS/YcfS/YnhG family protein Cbei_0756 21 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150016192 Common - RelA/SpoT domain protein Cbei_1310 29 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 150016594 Nonpathogen - hypothetical protein Cbei_1720 1 None None None 150015807 Nonpathogen - hypothetical protein Cbei_0921 1 None None None 150015633 Common - glycosyl hydrolase, BNR repeat-containing protein Cbei_0747 3 None None None 150016766 Common - methyl-accepting chemotaxis sensory transducer Cbei_1893 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018529 Common - cobalamin biosynthesis protein CbiM Cbei_3710 87 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 150015145 Nonpathogen - peptidase U32 Cbei_0253 6 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150017916 Common - transcriptional regulator, TetR family Cbei_3077 13 COG1309 AcrR, Transcriptional regulator Transcription 150016979 Common - arsenite-activated ATPase ArsA Cbei_2110 103 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 150019769 Common - large conductance mechanosensitive channel protein Cbei_4961 138 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150017729 Common - aldo/keto reductase Cbei_2881 67 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 150015458 Common - Rubrerythrin Cbei_0569 76 COG1592 COG1592, Rubrerythrin Energy production and conversion 150018644 Common - ABC transporter related Cbei_3826 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150018949 Nonpathogen - hypothetical protein Cbei_4137 1 None None None 150015476 Common - transcriptional regulator, TetR family Cbei_0587 47 COG1309 AcrR, Transcriptional regulator Transcription 150016094 Common - Sporulation protein YlmC/YmxH Cbei_1210 8 COG1873 COG1873, Uncharacterized conserved protein Function unknown 150019585 Common - dihydrodipicolinate synthase Cbei_4776 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150016656 Common - Integral membrane protein TerC Cbei_1783 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 150017088 Common - transcriptional regulator, BadM/Rrf2 family Cbei_2221 148 COG1959 COG1959, Predicted transcriptional regulator Transcription 150018152 Common - antibiotic transport-associated permease SpaG/MutG Cbei_3323 4 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 150019720 Common - PTS system, mannose/fructose/sorbose family, IIC subunit Cbei_4912 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150016242 Common - hypothetical protein Cbei_1360 13 None None None 150019816 Common - CMP/dCMP deaminase, zinc-binding Cbei_5008 212 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 150016704 Common - Alanine racemase Cbei_1831 129 COG1609 PurR, Transcriptional regulators Transcription 150019286 Common - ATP-dependent DNA helicase RecQ Cbei_4475 227 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 150017444 Common - glycosyl transferase, family 2 Cbei_2586 118 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150018886 Nonpathogen - hypothetical protein Cbei_4074 1 None None None 150019682 Common - uncharacterized secreted protein Cbei_4874 1 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 150017526 Common - Non-specific serine/threonine protein kinase Cbei_2671 144 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150019049 Common - hypothetical protein Cbei_4237 2 COG5298 COG5298, Uncharacterized protein conserved in bacteria Function unknown 150015496 Common - heavy metal translocating P-type ATPase Cbei_0607 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150019421 Nonpathogen - hypothetical protein Cbei_4611 1 None None None 150015247 Common - phosphodiesterase, MJ0936 family Cbei_0357 76 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150015837 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_0951 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150016484 Nonpathogen - hypothetical protein Cbei_1608 1 None None None 150018235 Common - putative cell wall binding repeat-containing protein Cbei_3407 47 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015677 Common - regulatory protein GntR, HTH Cbei_0791 97 COG1725 COG1725, Predicted transcriptional regulators Transcription 150016675 Common - pseudouridine synthase Cbei_1802 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150016887 Common - Exonuclease, RNase T and DNA polymerase III Cbei_2015 161 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 150016503 Common - hypothetical protein Cbei_1627 1 None None None 150019420 Common - small acid-soluble spore protein Tlp Cbei_4610 6 None None None 150017385 Common - diguanylate cyclase/phosphodiesterase Cbei_2527 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 150016517 Nonpathogen - hypothetical protein Cbei_1641 2 None None None 150017228 Common - NUDIX hydrolase Cbei_2366 119 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 150017311 Common - electron transport complex, RnfABCDGE type, G subunit Cbei_2451 70 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 150016058 Common - hypothetical protein Cbei_1174 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 150018919 Common - iron dependent repressor Cbei_4107 60 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 150016005 Common - sporulation sigma factor SigG Cbei_1121 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150015048 Common rplV 50S ribosomal protein L22 Cbei_0156 215 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 150016216 Common - hypothetical protein Cbei_1334 1 None None None 150015969 Common - Ig domain protein, group 2 domain protein Cbei_1083 26 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 150016867 Common - hypothetical protein Cbei_1995 10 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 150017611 Common - alanine racemase Cbei_2758 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 150016175 Common - threonine synthase Cbei_1293 133 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 150015520 Common - Nitrogenase Cbei_0631 60 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150017949 Common - putative transcriptional regulator, PucR family Cbei_3110 20 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 150017116 Common - SNARE associated Golgi protein Cbei_2251 24 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150019672 Common - excinuclease ABC subunit B Cbei_4864 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 150017399 Common - exsB protein Cbei_2541 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 150017414 Common - ybaK/ebsC protein Cbei_2556 109 COG2606 EbsC, Uncharacterized conserved protein Function unknown 150017337 Common - hypothetical protein Cbei_2478 5 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150017295 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_2435 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150016645 Common - nitrite and sulphite reductase 4Fe-4S region Cbei_1771 149 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 150016520 Common - hypothetical protein Cbei_1644 2 None None None 150017344 Common - integral membrane sensor signal transduction histidine kinase Cbei_2485 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150018460 Nonpathogen - Lytic transglycosylase, catalytic Cbei_3638 2 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150019094 Common - polysaccharide biosynthesis protein CapD Cbei_4282 166 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150015650 Common - aldo/keto reductase Cbei_0764 198 COG4989 COG4989, Predicted oxidoreductase General function prediction only 150015860 Common - Cof-like hydrolase Cbei_0974 129 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150018036 Nonpathogen - hypothetical protein Cbei_3204 1 None None None 150018051 Common - sodium:dicarboxylate symporter Cbei_3219 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 150019519 Common - UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase Cbei_4709 170 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 150019449 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_4639 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150019790 Common - PTS system, glucose subfamily, IIA subunit Cbei_4982 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 150015901 Common - biotin--acetyl-CoA-carboxylase ligase Cbei_1015 228 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 150019427 Common - diguanylate cyclase Cbei_4617 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150016375 Common - TfoX, N-terminal domain protein Cbei_1497 9 COG3070 TfoX, Regulator of competence-specific genes Transcription 150015721 Common - protein of unknown function DUF558 Cbei_0835 205 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 150015031 Common nusG transcription antitermination protein NusG Cbei_0139 215 COG0250 NusG, Transcription antiterminator Transcription 150015263 Common - transcriptional regulator Cbei_0373 25 None None None 150014914 Common - Domain of unknown function DUF1836 Cbei_0022 8 None None None 150019534 Common - methyl-accepting chemotaxis sensory transducer Cbei_4724 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015699 Common - anti-sigma F factor Cbei_0813 37 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 150018818 Common - butyrate kinase Cbei_4006 132 COG3426 COG3426, Butyrate kinase Energy production and conversion 150017090 Common - hypothetical protein Cbei_2223 4 None None None 150015560 Nonpathogen - hypothetical protein Cbei_0671 2 None None None 150018890 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_4078 83 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019255 Common - binding-protein-dependent transport systems inner membrane component Cbei_4444 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150018412 Common - transcriptional regulator, LysR family Cbei_3589 192 COG0583 LysR, Transcriptional regulator Transcription 150016051 Common rpmF 50S ribosomal protein L32 Cbei_1167 64 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 150019061 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG Cbei_4249 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150016512 Common - hypothetical protein Cbei_1636 13 None None None 150015003 Common - amidohydrolase-like protein Cbei_0111 57 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150017779 Common - Dihydrodipicolinate reductase Cbei_2934 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 150016806 Nonpathogen - hypothetical protein Cbei_1934 1 None None None 150016706 Common - altronate oxidoreductase Cbei_1833 88 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150018580 Common - transport system permease protein Cbei_3761 191 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 150018624 Common - hypothetical protein Cbei_3805 3 None None None 150019240 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_4429 42 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017677 Common - Carbohydrate-binding family V/XII Cbei_2826 23 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 150014939 Common - Alanine racemase Cbei_0047 129 COG1609 PurR, Transcriptional regulators Transcription 150015933 Common - hypothetical protein Cbei_1047 5 None None None 150017261 Common - peptidase M16 domain protein Cbei_2401 202 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150017772 Common - GntR domain protein Cbei_2927 150 COG2186 FadR, Transcriptional regulators Transcription 150018673 Common - ABC transporter related Cbei_3856 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150019801 Nonpathogen - hypothetical protein Cbei_4993 1 None None None 150017648 Common - Mug G:T/U mismatch-specific DNA glycosylase Cbei_2796 42 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 150019102 Nonpathogen - hypothetical protein Cbei_4290 1 None None None 150016415 Common secF preprotein translocase subunit SecF Cbei_1537 216 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 150015489 Common - phosphoglyceromutase Cbei_0600 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 150018787 Common - putative cell wall binding repeat-containing protein Cbei_3975 9 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 150019437 Common - UDP-N-acetylglucosamine 2-epimerase Cbei_4627 152 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 150018975 Common - metal dependent phosphohydrolase Cbei_4163 126 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150018528 Common - cobalt/cobalamin transport protein CbiN Cbei_3709 30 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 150016974 Common - GCN5-related N-acetyltransferase Cbei_2105 10 COG0456 RimI, Acetyltransferases General function prediction only 150015076 Common - cobalt transport protein Cbei_0184 91 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150017033 Nonpathogen - hypothetical protein Cbei_2164 1 None None None 150017978 Common - ThiJ/PfpI domain protein Cbei_3140 36 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 150017350 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Cbei_2491 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150019249 Common - methyl-accepting chemotaxis sensory transducer Cbei_4438 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018775 Nonpathogen - hypothetical protein Cbei_3963 1 None None None 150019498 Common - diguanylate cyclase with PAS/PAC sensor Cbei_4688 189 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150019784 Common - transcriptional regulator, RpiR family Cbei_4976 25 COG1737 RpiR, Transcriptional regulators Transcription 150016835 Common - phage integrase family protein Cbei_1963 223 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150015747 Common - ABC transporter related Cbei_0861 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 150016868 Common - DNA binding domain, excisionase family Cbei_1996 70 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 150019436 Common - glycosyl transferase, group 1 Cbei_4626 111 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150017232 Nonpathogen - acetyltransferase Cbei_2370 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150018861 Common - hypothetical protein Cbei_4049 9 None None None 150015955 Common - 2-nitropropane dioxygenase, NPD Cbei_1069 147 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 150019671 Common - excinuclease ABC, A subunit Cbei_4863 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 150016088 Common - phosphoesterase, RecJ domain protein Cbei_1204 83 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 150017162 Nonpathogen - hypothetical protein Cbei_2300 1 None None None 150019288 Common - transposase and inactivated derivatives Cbei_4477 35 None None None 150015272 Common - glycosyl transferase, group 1 Cbei_0382 195 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150017644 Common - MazG nucleotide pyrophosphohydrolase Cbei_2792 43 COG1694 MazG, Predicted pyrophosphatase General function prediction only 150016845 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_1973 215 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150017808 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Cbei_2965 96 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 150016901 Common - transposase IS3/IS911 family protein Cbei_2030 26 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 150015514 Common - binding-protein-dependent transport systems inner membrane component Cbei_0625 104 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 150016097 Common - cell divisionFtsK/SpoIIIE Cbei_1213 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 150018905 Nonpathogen - hypothetical protein Cbei_4093 1 None None None 150019331 Common - acetylornithine and succinylornithine aminotransferase Cbei_4520 236 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150017137 Nonpathogen - hypothetical protein Cbei_2274 3 None None None 150016728 Common - protein of unknown function DUF342 Cbei_1855 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 150015051 Common - ribosomal protein L29 Cbei_0159 145 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 150016554 Common - MgtC/SapB transporter Cbei_1679 118 COG1285 SapB, Uncharacterized membrane protein Function unknown 150018236 Nonpathogen - hypothetical protein Cbei_3408 1 None None None 150016142 Common - hypothetical protein Cbei_1260 13 COG3888 COG3888, Predicted transcriptional regulator Transcription 150016721 Common - FeS assembly ATPase SufC Cbei_1848 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 150016167 Common hemC porphobilinogen deaminase Cbei_1285 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 150019508 Common - cell wall hydrolase/autolysin Cbei_4698 183 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150015471 Common - ferric uptake regulator, Fur family Cbei_0582 142 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150015910 Common - beta-lactamase domain protein Cbei_1024 129 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 150017365 Common - transposase Cbei_2507 6 None None None 150017225 Common - protein of unknown function DUF1680 Cbei_2363 31 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 150019452 Common - transcriptional regulator, RpiR family Cbei_4642 97 COG1737 RpiR, Transcriptional regulators Transcription 150018733 Nonpathogen - hypothetical protein Cbei_3919 1 None None None 150018532 Common - protein of unknown function DUF1540 Cbei_3713 2 None None None 150019217 Nonpathogen - hypothetical protein Cbei_4406 1 None None None 150019307 Common - two component transcriptional regulator, winged helix family Cbei_4496 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016659 Common - hypothetical protein Cbei_1786 7 None None None 150017417 Common - hypothetical protein Cbei_2559 1 None None None 150019154 Common - ABC transporter related Cbei_4342 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150015702 Common - stage V sporulation protein AD Cbei_0816 15 None None None 150015661 Common - hypothetical protein Cbei_0775 4 None None None 150016853 Common - uracil-xanthine permease Cbei_1981 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150019527 Common - putative cell wall binding repeat-containing protein Cbei_4717 7 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016194 Common - aminotransferase, class V Cbei_1312 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 150018466 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3645 17 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150018539 Common - hypothetical protein Cbei_3720 5 None None None 150014991 Common - hypoxanthine phosphoribosyltransferase Cbei_0099 154 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 150017818 Common - cytochrome c biogenesis protein, transmembrane region Cbei_2976 147 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 150016928 Common - DSBA oxidoreductase Cbei_2058 86 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 150017431 Common - conserved hypothetical protein 245 Cbei_2573 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 150016953 Common - Lysine exporter protein (LYSE/YGGA) Cbei_2084 67 COG1279 COG1279, Lysine efflux permease General function prediction only 150018081 Common - small acid-soluble spore protein, alpha/beta type Cbei_3250 12 None None None 150018351 Common - short chain dehydrogenase Cbei_3527 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150014984 Common - RNA-binding S4 domain protein Cbei_0092 46 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 150015279 Common - Glutathione peroxidase Cbei_0389 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 150018762 Common - transcriptional repressor, LexA family Cbei_3950 55 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150015738 Common dnaG DNA primase Cbei_0852 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 150015108 Common - 3-isopropylmalate dehydrogenase Cbei_0216 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 150019239 Common - D-galactose-binding periplasmic protein precursor Cbei_4428 97 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018838 Common - hypothetical protein Cbei_4026 16 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 150018004 Nonpathogen - hypothetical protein Cbei_3170 1 None None None 150019589 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_4780 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150016589 Common - uracil transporter Cbei_1715 132 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150017371 Common - extracellular solute-binding protein, family 3 Cbei_2513 182 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150018165 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_3336 190 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018830 Common - putative CheW protein Cbei_4018 132 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150018665 Common - integral membrane sensor signal transduction histidine kinase Cbei_3848 106 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017522 Common - fatty acid desaturase Cbei_2667 12 COG3239 DesA, Fatty acid desaturase Lipid metabolism 150019612 Common - protein of unknown function DUF156 Cbei_4803 92 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 150015616 Common - hypothetical protein Cbei_0730 3 None None None 150018521 Common - periplasmic binding protein Cbei_3702 171 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150016667 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase, DNA binding Cbei_1794 70 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 150019531 Common - cell wall/surface repeat protein Cbei_4721 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015946 Common - phosphoribosylamine--glycine ligase Cbei_1060 234 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 150018433 Nonpathogen - hypothetical protein Cbei_3611 1 None None None 150018519 Common - protein of unknown function DUF445 Cbei_3700 52 COG2733 COG2733, Predicted membrane protein Function unknown 150018587 Common - PTS system, glucose subfamily, IIA subunit Cbei_3768 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 150019281 Common - PHP C-terminal domain protein Cbei_4470 129 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 150017947 Common - MMPL domain protein Cbei_3108 115 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 150019724 Common - UBA/THIF-type NAD/FAD binding protein Cbei_4916 218 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 150016344 Common - Alcohol dehydrogenase GroES domain protein Cbei_1464 213 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150018993 Common - Protein-glutamate O-methyltransferase Cbei_4181 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 150018752 Common - GCN5-related N-acetyltransferase Cbei_3940 32 COG0456 RimI, Acetyltransferases General function prediction only 150019669 Common - cell cycle protein Cbei_4861 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150019696 Common - NLP/P60 protein Cbei_4888 152 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150015772 Common - transcriptional regulator, XRE family Cbei_0886 29 COG1476 COG1476, Predicted transcriptional regulators Transcription 150017755 Common - N-acetylgalactosamine-specific PTS system transporter subunit IIB Cbei_2908 39 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150019719 Common - PTS system, mannose/fructose/sorbose family, IID subunit Cbei_4911 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150018155 Common - protein of unknown function DUF975 Cbei_3326 19 COG5523 COG5523, Predicted integral membrane protein Function unknown 150015162 Common - dipeptidyl aminopeptidase/acylaminoacyl-peptidase related protein Cbei_0272 39 COG2267 PldB, Lysophospholipase Lipid metabolism 150018175 Common - putative galactoside ABC transporter Cbei_3347 73 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016305 Common - permease Cbei_1425 8 None None None 150019794 Common - putative cell wall binding repeat-containing protein Cbei_4986 5 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019300 Common - thiamine biosynthesis protein ThiC Cbei_4489 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 150018379 Nonpathogen - hypothetical protein Cbei_3555 1 None None None 150019229 Nonpathogen - RNA-binding region-containing protein (RNP-1) Cbei_4418 1 None None None 150019808 Nonpathogen - hypothetical protein Cbei_5000 1 None None None 150018927 Common - hypothetical protein Cbei_4115 31 COG1160 COG1160, Predicted GTPases General function prediction only 150019383 Common - shikimate 5-dehydrogenase Cbei_4572 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 150015874 Common - glycosyl transferase, group 1 Cbei_0988 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150018282 Common - putative transcriptional regulator, MerR family Cbei_3455 59 COG0789 SoxR, Predicted transcriptional regulators Transcription 150015403 Common nadD nicotinic acid mononucleotide adenyltransferase Cbei_0513 175 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 150017758 Common - Na+/H+ antiporter Cbei_2913 104 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 150018122 Common - Thioredoxin domain Cbei_3293 25 None None None 150017952 Nonpathogen - hypothetical protein Cbei_3113 2 None None None 150015540 Common - diguanylate cyclase/phosphodiesterase Cbei_0651 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150017665 Nonpathogen - hypothetical protein Cbei_2813 1 None None None 150017284 Common - diguanylate cyclase/phosphodiesterase Cbei_2424 175 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150015241 Common - UvrD/REP helicase Cbei_0351 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150015670 Common - anaerobic sulfite reductase subunit B Cbei_0784 137 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150016988 Nonpathogen - hypothetical protein Cbei_2119 1 None None None 150015507 Common - binding-protein-dependent transport systems inner membrane component Cbei_0618 188 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150016744 Common - hypothetical protein Cbei_1871 1 None None None 150015536 Common - thiamine biosynthesis protein ThiF Cbei_0647 189 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 150018346 Nonpathogen - hypothetical protein Cbei_3521 2 None None None 150014900 Common - putative metal dependent phosphohydrolase Cbei_0008 4 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150017847 Common - hydrogenase expression/formation protein HypE Cbei_3006 120 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 150018604 Common - two component transcriptional regulator, LuxR family Cbei_3785 206 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150015273 Common - Spore coat protein CotS Cbei_0383 4 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 150017306 Common - ornithine carbamoyltransferase Cbei_2446 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 150017082 Common - peptidase M48, Ste24p Cbei_2213 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 150019097 Common - hypothetical protein Cbei_4285 12 None None None 150017572 Common - hypothetical protein Cbei_2719 23 COG4832 COG4832, Uncharacterized conserved protein Function unknown 150019880 Common - acyl-ACP thioesterase Cbei_5072 22 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 150019761 Common - Dihydrofolate reductase Cbei_4953 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 150017277 Common - protein of unknown function UPF0118 Cbei_2417 193 COG0628 PerM, Predicted permease General function prediction only 150019623 Common - multi-sensor hybrid histidine kinase Cbei_4814 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019889 Common rplI 50S ribosomal protein L9 Cbei_5081 211 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 150016560 Nonpathogen - hypothetical protein Cbei_1686 1 None None None 150016221 Common - UvrD/REP helicase Cbei_1339 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150017326 Common - transcriptional regulator, DeoR family Cbei_2466 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150015558 Common - putative PAS/PAC sensor protein Cbei_0669 100 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150016514 Common - hypothetical protein Cbei_1638 5 None None None 150018118 Nonpathogen - hypothetical protein Cbei_3289 1 None None None 150015823 Common - LrgB family protein Cbei_0937 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 150019124 Common - protein of unknown function DUF342 Cbei_4312 31 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 150016998 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Cbei_2129 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 150015625 Common - NADPH-dependent FMN reductase Cbei_0739 44 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150015916 Common - hypothetical protein Cbei_1030 6 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 150015165 Common - iron dependent repressor Cbei_0275 89 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 150017934 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3095 119 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019458 Common - PfkB domain protein Cbei_4648 172 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150015604 Common - transcriptional regulator, MarR family Cbei_0718 18 COG1846 MarR, Transcriptional regulators Transcription 150017290 Common - helicase domain protein Cbei_2430 106 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150018360 Common - regulatory protein, ArsR Cbei_3536 78 COG0640 ArsR, Predicted transcriptional regulators Transcription 150015138 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Cbei_0246 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 150018199 Common - gluconate 5-dehydrogenase Cbei_3371 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150018707 Common - aminotransferase class-III Cbei_3891 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 150019172 Nonpathogen - Domain of unknown function DUF1874 Cbei_4360 3 None None None 150017872 Common - putative transcriptional regulator, XRE family Cbei_3031 51 COG3655 COG3655, Predicted transcriptional regulator Transcription 150016374 Common - hypothetical protein Cbei_1495 6 None None None 150015754 Common - DNA topoisomerase Cbei_0868 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150017159 Nonpathogen - hypothetical protein Cbei_2297 1 None None None 150018203 Common - transcriptional regulator, AbrB family Cbei_3375 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150018645 Common - transcriptional regulator, XRE family Cbei_3827 21 COG1396 HipB, Predicted transcriptional regulators Transcription 150015683 Common - hypothetical protein Cbei_0797 2 None None None 150019051 Common - transmembrane protein Cbei_4239 6 None None None 150019489 Common - binding-protein-dependent transport systems inner membrane component Cbei_4679 171 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150019768 Common - pyruvate carboxylase Cbei_4960 242 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 150017579 Common - response regulator receiver protein Cbei_2726 209 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150018906 Common - phage shock protein C, PspC Cbei_4094 37 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 150017129 Common - hypothetical protein Cbei_2266 1 None None None 150018275 Nonpathogen - hypothetical protein Cbei_3448 1 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 150019144 Common - amino acid adenylation domain Cbei_4332 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150014909 Common - histidine kinase Cbei_0017 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150019021 Common - von Willebrand factor, type A Cbei_4209 4 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 150016567 Common - stage III sporulation protein SpoAB Cbei_1693 12 None None None 150016961 Common - transcriptional regulator, TrmB Cbei_2092 69 COG1846 MarR, Transcriptional regulators Transcription 150017067 Nonpathogen - hypothetical protein Cbei_2198 1 None None None 150018180 Common - sigma54 specific transcriptional regulator, Fis family Cbei_3352 177 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150017240 Common - signal transduction histidine kinase, LytS Cbei_2378 123 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150015087 Common nrdF ribonucleotide-diphosphate reductase subunit beta Cbei_0195 162 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 150016443 Common - hypothetical protein Cbei_1567 3 None None None 150018748 Common - putative cell wall binding repeat-containing protein Cbei_3936 4 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015111 Common - sigma-54 factor, interaction domain-containing protein Cbei_0219 167 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 150017761 Common - NHL repeat containing protein Cbei_2916 13 COG2433 COG2433, Uncharacterized conserved protein Function unknown 150019028 Nonpathogen - putative type IV pilin Cbei_4216 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150016624 Common - glutamine amidotransferase of anthranilate synthase Cbei_1750 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 150018651 Common - 3-oxoacid CoA-transferase, B subunit Cbei_3834 108 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 150014924 Common - glutamate racemase Cbei_0032 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 150017076 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cbei_2207 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150019827 Common - PTS system, glucose-like IIB subunint Cbei_5019 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150017026 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_2157 30 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 150017971 Common - transcriptional regulator, LysR family Cbei_3133 192 COG0583 LysR, Transcriptional regulator Transcription 150019477 Common - sulfatase Cbei_4667 62 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 150016664 Common - Tetrahydrodipicolinate succinyltransferase N-terminal domain protein Cbei_1791 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 150016228 Nonpathogen - hypothetical protein Cbei_1346 3 None None None 150016601 Common - UTP-glucose-1-phosphate uridylyltransferase Cbei_1727 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150017824 Nonpathogen - hypothetical protein Cbei_2982 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150016811 Common - binding-protein-dependent transport systems inner membrane component Cbei_1939 152 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150016999 Nonpathogen - hypothetical protein Cbei_2130 1 None None None 150019470 Common - transcriptional regulator, GntR family Cbei_4660 129 COG1802 GntR, Transcriptional regulators Transcription 150016828 Common - hypothetical protein Cbei_1956 2 None None None 150018480 Common - helix-turn-helix domain protein Cbei_3660 42 None None None 150016269 Common - polysaccharide biosynthesis protein Cbei_1388 57 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150019541 Common - glycosyl transferase, family 2 Cbei_4731 210 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150018335 Common - protein of unknown function DUF1234 Cbei_3510 49 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 150019643 Common - Catalase Cbei_4834 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 150017965 Common - phosphopentomutase Cbei_3127 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 150016348 Common - cation diffusion facilitator family transporter Cbei_1468 216 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150015433 Common - PTS system Galactitol-specific IIC component Cbei_0543 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 150018874 Common - intracellular protease, PfpI family Cbei_4062 126 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 150015583 Common - Barstar (barnase inhibitor) Cbei_0697 11 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 150018103 Common - putative glucan-binding protein D; BglB-like protein Cbei_3272 18 COG4099 COG4099, Predicted peptidase General function prediction only 150017502 Common - acetolactate synthase, large subunit, biosynthetic type Cbei_2646 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150017041 Common - response regulator receiver and SARP domain protein Cbei_2172 211 COG3947 COG3947, Response regulator containing CheY-like receiver and SARP domains Signal transduction mechanisms 150018715 Nonpathogen - hypothetical protein Cbei_3899 1 None None None 150015797 Nonpathogen - phage head-tail adaptor, putative Cbei_0911 2 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 150017386 Common - hypothetical protein Cbei_2528 10 None None None 150018658 Nonpathogen - hypothetical protein Cbei_3841 2 None None None 150016544 Common - D-galactose-binding periplasmic protein precursor Cbei_1668 68 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017188 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cbei_2326 122 COG0546 Gph, Predicted phosphatases General function prediction only 150019570 Common - putative cell wall binding repeat-containing protein Cbei_4761 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017909 Common - putative galactoside ABC transporter Cbei_3070 53 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015961 Common - biotin carboxylase Cbei_1075 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 150018692 Common - PfkB domain protein Cbei_3876 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150015445 Common - two component transcriptional regulator, LytTR family Cbei_0556 209 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150017372 Common - metal dependent phosphohydrolase Cbei_2514 112 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150017400 Common - 7-cyano-7-deazaguanine reductase Cbei_2542 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 150017751 Common - phosphosugar isomerase Cbei_2904 40 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 150015344 Common - Rhamnulose-1-phosphate aldolase Cbei_0454 30 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 150018242 Common - Lysine exporter protein (LYSE/YGGA) Cbei_3414 111 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 150015592 Common - transcriptional regulator, MarR family Cbei_0706 58 COG1846 MarR, Transcriptional regulators Transcription 150018396 Common - ApbE family lipoprotein Cbei_3572 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150016075 Common frr ribosome recycling factor Cbei_1191 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 150015478 Common - two component transcriptional regulator, winged helix family Cbei_0589 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016068 Common - Mg chelatase, subunit ChlI Cbei_1184 200 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 150018372 Common - Radical SAM domain protein Cbei_3548 92 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150018619 Common - molybdenum cofactor synthesis domain Cbei_3800 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 150018667 Common - hypothetical protein Cbei_3850 2 None None None 150019117 Common - response regulator receiver protein Cbei_4305 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150016452 Common mraW S-adenosyl-methyltransferase MraW Cbei_1576 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 150017270 Common - flavodoxin Cbei_2410 10 COG0716 FldA, Flavodoxins Energy production and conversion 150015907 Common - nitroreductase Cbei_1021 82 COG0778 NfnB, Nitroreductase Energy production and conversion 150017376 Common - aldehyde dehydrogenase Cbei_2518 45 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150017699 Nonpathogen - methyl-accepting chemotaxis protein Cbei_2850 1 None None None 150019295 Common - multi-sensor signal transduction histidine kinase Cbei_4484 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150018192 Common - natural resistance-associated macrophage protein Cbei_3364 108 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 150019179 Common - DNA ligase-like protein Cbei_4367 11 None None None 150017407 Common - Ferritin, Dps family protein Cbei_2549 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 150017663 Common - hypothetical protein Cbei_2811 8 COG4997 COG4997, Uncharacterized conserved protein Function unknown 150019482 Common - hypothetical protein Cbei_4672 6 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 150018217 Common - hypothetical protein Cbei_3389 3 None None None 150018687 Common - PTS system, mannose/fructose/sorbose family, IID subunit Cbei_3871 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150018725 Nonpathogen - hypothetical protein Cbei_3911 1 None None None 150019070 Common - flagellar basal body-associated protein FliL Cbei_4258 13 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 150017514 Common - pseudouridine synthase Cbei_2659 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150014928 Common - Peptidoglycan-binding domain 1 protein Cbei_0036 57 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150015453 Nonpathogen - hypothetical protein Cbei_0564 1 None None None 150019632 Common - methyl-accepting chemotaxis sensory transducer Cbei_4823 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018228 Nonpathogen - hypothetical protein Cbei_3400 1 None None None 150018796 Common - glycoside hydrolase, family 1 Cbei_3984 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150016149 Common - Phosphoglycerate mutase Cbei_1267 71 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150016406 Nonpathogen - hypothetical protein Cbei_1528 2 None None None 150016133 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_1250 5 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150017087 Common - transcriptional regulator, AbrB family Cbei_2219 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150016363 Common - protein of unknown function DUF107 Cbei_1483 12 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 150017748 Common - PTS system mannose/fructose/sorbose family IID component Cbei_2901 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150018626 Common - anaerobic ribonucleoside-triphosphate reductase activating protein Cbei_3807 69 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 150018636 Common - sensory histidine kinase AtoS Cbei_3818 223 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 150018369 Common - aminoglycoside phosphotransferase Cbei_3545 12 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 150017714 Common - hypothetical protein Cbei_2865 4 None None None 150018403 Common - AraC-type transcriptional regulator domain protein Cbei_3579 92 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019311 Common - putative esterase Cbei_4500 37 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 150017883 Nonpathogen - hypothetical protein Cbei_3042 1 None None None 150015058 Common rplF 50S ribosomal protein L6 Cbei_0166 241 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 150017803 Common - cytochrome c biogenesis protein, transmembrane region Cbei_2960 169 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 150019561 Common - dTDP-4-dehydrorhamnose reductase Cbei_4752 195 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 150015966 Common - inner-membrane translocator Cbei_1080 51 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 150015679 Common - L-aspartate oxidase Cbei_0793 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 150017874 Common - hypothetical protein Cbei_3033 7 None None None 150015883 Common - undecaprenyl pyrophosphate phosphatase Cbei_0997 195 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 150016208 Common tig trigger factor Cbei_1326 212 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 150016463 Common - protein of unknown function DUF881 Cbei_1587 23 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 150019390 Common - sensor histidine kinase-like protein Cbei_4579 26 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150015351 Common - PfkB domain protein Cbei_0461 200 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150019890 Common - phosphoesterase, RecJ domain protein Cbei_5082 98 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 150016552 Nonpathogen - hypothetical protein Cbei_1677 1 None None None 150017131 Common - phage replisome organizer, putative Cbei_2268 4 None None None 150017091 Nonpathogen - hypothetical protein Cbei_2224 3 None None None 150016599 Common - glycosyl transferase, family 39 Cbei_1725 26 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 150018590 Common - glycoside hydrolase, family 3 domain protein Cbei_3771 123 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150019775 Common - Monosaccharide-transporting ATPase Cbei_4967 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 150019472 Common - permease Cbei_4662 55 COG0701 COG0701, Predicted permeases General function prediction only 150015288 Common - CTP synthetase Cbei_0398 247 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 150019092 Common - GCN5-related N-acetyltransferase Cbei_4280 64 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150017556 Common - efflux transporter, RND family, MFP subunit Cbei_2702 172 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150018523 Common - ABC transporter related Cbei_3704 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150016641 Common - Extracellular ligand-binding receptor Cbei_1767 142 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 150016244 Nonpathogen - hypothetical protein Cbei_1362 1 None None None 150016509 Common - hypothetical protein Cbei_1633 2 None None None 150014955 Common - hypothetical protein Cbei_0063 1 None None None 150015199 Common - GntR domain protein Cbei_0309 161 COG2186 FadR, Transcriptional regulators Transcription 150017464 Nonpathogen - hypothetical protein Cbei_2606 1 None None None 150016398 Common thiH thiamine biosynthesis protein ThiH Cbei_1520 55 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 150017395 Common - hypothetical protein Cbei_2537 2 None None None 150015674 Common - amino acid permease-associated region Cbei_0788 176 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 150017475 Nonpathogen - hypothetical protein Cbei_2619 1 None None None 150018056 Nonpathogen - hypothetical protein Cbei_3224 4 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 150019425 Common - tyrosyl-tRNA synthetase Cbei_4615 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150019680 Common - transcriptional modulator of MazE/toxin, MazF Cbei_4872 62 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 150017349 Common - Rubrerythrin Cbei_2490 22 COG1592 COG1592, Rubrerythrin Energy production and conversion 150017712 Common - acriflavin resistance protein Cbei_2863 184 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150018071 Common - Cupin 2, conserved barrel domain protein Cbei_3240 43 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150019203 Nonpathogen - hypothetical protein Cbei_4392 1 None None None 150019442 Common - glycosyl transferase, family 2 Cbei_4632 216 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150019843 Common - aminoglycoside phosphotransferase Cbei_5035 27 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 150015526 Common - binding-protein-dependent transport systems inner membrane component Cbei_0637 169 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 150015636 Common - GreA/GreB family elongation factor Cbei_0750 172 COG0782 GreA, Transcription elongation factor Transcription 150015652 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Cbei_0766 207 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150015835 Common - glycoside hydrolase, family 46 Cbei_0949 4 None None None 150016177 Common - hypothetical protein Cbei_1295 14 COG4492 PheB, ACT domain-containing protein General function prediction only 150018740 Common - signal peptidase I Cbei_3928 195 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150019173 Common - Radical SAM domain protein Cbei_4361 28 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 150018502 Nonpathogen - hypothetical protein Cbei_3682 1 None None None 150015452 Common - hypothetical protein Cbei_0563 1 None None None 150015899 Common - Exonuclease, RNase T and DNA polymerase III Cbei_1013 21 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 150014916 Common - gamma-glutamyl kinase Cbei_0024 199 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 150018578 Common - FAD linked oxidase domain protein Cbei_3759 54 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150015599 Common - PTS system, mannose/fructose/sorbose family, IID subunit Cbei_0713 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150015723 Common - histidine triad (HIT) protein Cbei_0837 234 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 150019086 Common - flagellin domain protein Cbei_4274 115 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 150019063 Common - Cobyrinic acid a,c-diamide synthase Cbei_4251 237 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150015795 Common - phage major capsid protein, HK97 family Cbei_0909 3 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 150016383 Common - natural resistance-associated macrophage protein Cbei_1505 114 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 150015313 Common - peptidase M23B Cbei_0423 8 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150019736 Common - extracellular solute-binding protein, family 5 Cbei_4928 204 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 150017095 Common - putative transcriptional regulator Cbei_2228 6 COG2345 COG2345, Predicted transcriptional regulator Transcription 150017249 Common - transketolase Cbei_2387 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 150014956 Common - Mrp/NBP35 ATP-binding family protein Cbei_0064 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150018326 Common - extracellular solute-binding protein, family 1 Cbei_3501 57 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018034 Common - hypothetical protein Cbei_3202 14 COG4994 COG4994, Uncharacterized protein conserved in bacteria Function unknown 150016098 Common - MiaB-like tRNA modifying enzyme YliG Cbei_1214 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150015519 Common - Pyridoxal-5'-phosphate-dependent protein, beta subunit Cbei_0630 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150016501 Nonpathogen - hypothetical protein Cbei_1625 1 None None None 150018354 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cbei_3530 8 None None None 150015767 Nonpathogen - hypothetical protein Cbei_0881 1 None None None 150014945 Common - peptidase M24 Cbei_0053 241 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150017994 Common - protein of unknown function DUF262 Cbei_3159 50 None None None 150016217 Common - hypothetical protein Cbei_1335 1 None None None 150018555 Common - major facilitator superfamily MFS_1 Cbei_3736 166 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019579 Nonpathogen - hypothetical protein Cbei_4770 1 None None None 150016160 Common - hypothetical protein Cbei_1278 53 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 150016579 Common - Polyprenyl synthetase Cbei_1705 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 150015192 Common - transcriptional regulator, MarR family Cbei_0302 20 COG1846 MarR, Transcriptional regulators Transcription 150017768 Common - secretion protein HlyD family protein Cbei_2923 166 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150018189 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cbei_3361 97 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150016482 Common - Fibronectin, type III domain protein Cbei_1606 90 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 150016108 Common - riboflavin biosynthesis protein RibD Cbei_1224 234 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 150015718 Common - nitrite and sulphite reductase 4Fe-4S region Cbei_0832 146 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 150016736 Nonpathogen - hypothetical protein Cbei_1863 2 None None None 150015639 Common - hypothetical protein Cbei_0753 3 COG4915 XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein General function prediction only 150016464 Common - alanine racemase domain protein Cbei_1588 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 150017548 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cbei_2693 123 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150019268 Common - L-arabinose isomerase Cbei_4457 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 150015990 Common - Holliday junction resolvase-like protein Cbei_1106 183 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 150017342 Common - hypothetical protein Cbei_2483 3 None None None 150016686 Common - peptidase M42 family protein Cbei_1813 75 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 150015760 Common - transferase hexapeptide repeat containing protein Cbei_0874 126 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150017470 Nonpathogen - hypothetical protein Cbei_2614 1 None None None 150019742 Common - putrescine--2-oxoglutarate aminotransferase Cbei_4934 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150019002 Common - sulfate ABC transporter, ATPase subunit Cbei_4190 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 150014978 Common - transcription-repair coupling factor Cbei_0086 235 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 150015818 Common - transcriptional regulator, XRE family Cbei_0932 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 150015258 Common - polysaccharide deacetylase Cbei_0368 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150018684 Common - two component transcriptional regulator, LuxR family Cbei_3867 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150016701 Common - bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein Cbei_1828 177 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 150017065 Common - PTS system mannose/fructose/sorbose family IID component Cbei_2196 36 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150017944 Common - dihydrouridine synthase, DuS Cbei_3105 193 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 150016996 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Cbei_2127 14 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 150016522 Common - hypothetical protein Cbei_1646 2 None None None 150019039 Common - GTP-binding protein, HSR1-related Cbei_4227 218 COG2262 HflX, GTPases General function prediction only 150015711 Common - GTP-binding protein LepA Cbei_0825 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 150018643 Common - ABC transporter permease protein Cbei_3825 7 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 150017910 Common - GCN5-related N-acetyltransferase Cbei_3071 15 COG3393 COG3393, Predicted acetyltransferase General function prediction only 150015363 Nonpathogen - hypothetical protein Cbei_0473 1 None None None 150018037 Common - hypothetical protein Cbei_3205 2 None None None 150017617 Common - hypothetical protein Cbei_2764 14 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 150016390 Common - Auxin Efflux Carrier Cbei_1512 123 COG0679 COG0679, Predicted permeases General function prediction only 150017736 Common - nitroreductase Cbei_2888 31 COG0778 NfnB, Nitroreductase Energy production and conversion 150019043 Nonpathogen - hypothetical protein Cbei_4231 1 None None None 150019009 Common - FeoA family protein Cbei_4197 58 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 150015245 Common - AIR synthase related protein domain protein Cbei_0355 149 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 150017286 Common - uracil-xanthine permease Cbei_2426 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 150018530 Common - ABC transporter related Cbei_3711 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150019552 Common - lipopolysaccharide biosynthesis protein Cbei_4742 20 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 150016570 Common - Sporulation stage III, protein AE Cbei_1696 15 None None None 150016789 Common - glucokinase regulatory-like protein Cbei_1917 84 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 150018550 Common - hypothetical protein Cbei_3731 1 None None None 150017798 Nonpathogen - hypothetical protein Cbei_2955 1 None None None 150015953 Common - transcriptional regulator, MarR family Cbei_1067 48 COG1846 MarR, Transcriptional regulators Transcription 150015935 Common - extracellular solute-binding protein, family 3 Cbei_1049 183 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150016917 Common - two component transcriptional regulator, winged helix family Cbei_2047 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150019714 Common - alpha amylase, catalytic region Cbei_4906 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150015984 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Cbei_1100 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 150015234 Common - Lytic transglycosylase, catalytic Cbei_0344 166 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150018362 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3538 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150015923 Common - protein of unknown function DUF327 Cbei_1037 18 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 150016015 Common - phosphate uptake regulator, PhoU Cbei_1131 202 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 150019188 Common - hypothetical protein Cbei_4377 5 None None None 150018197 Common - L-rhamnose 1-epimerase Cbei_3369 28 COG3254 COG3254, Uncharacterized conserved protein Function unknown 150015499 Common - ABC transporter related Cbei_0610 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150016772 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_1899 132 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150018060 Nonpathogen - hypothetical protein Cbei_3228 1 None None None 150017560 Common - peptidase M24 Cbei_2706 230 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150015647 Common - ribose 5-phosphate isomerase Cbei_0761 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 150017904 Common - heavy metal translocating P-type ATPase Cbei_3064 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150018883 Common - uncharacterized membrane protein Cbei_4071 11 COG1971 COG1971, Predicted membrane protein Function unknown 150016634 Common - MATE efflux family protein Cbei_1760 169 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150017720 Common - TrkA-C domain protein Cbei_2872 43 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 150016892 Common - hypothetical protein Cbei_2020 5 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 150018591 Common - PTS system, glucose-like IIB subunint Cbei_3772 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150015878 Nonpathogen - hypothetical protein Cbei_0992 1 None None None 150018828 Common - histidine kinase Cbei_4016 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015067 Common - translation initiation factor IF-1 Cbei_0175 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 150017250 Nonpathogen - hypothetical protein Cbei_2388 2 None None None 150017727 Common - transposase Cbei_2879 6 None None None 150016200 Common - aminotransferase, class I and II Cbei_1318 237 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150016210 Common clpX ATP-dependent protease ATP-binding subunit Cbei_1328 238 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 150018263 Common - transcriptional regulator, AraC family Cbei_3436 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015400 Common rpmA 50S ribosomal protein L27 Cbei_0510 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 150018167 Common - hypothetical protein Cbei_3338 3 None None None 150015065 Common - methionine aminopeptidase, type I Cbei_0173 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 150016759 Common - ABC transporter related Cbei_1886 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150016034 Common - Protein phosphatase 2C-like protein Cbei_1150 133 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 150016257 Nonpathogen - Ig domain protein, group 2 domain protein Cbei_1375 4 None None None 150018078 Nonpathogen - hypothetical protein Cbei_3247 1 None None None 150019514 Common - glycoside hydrolase, family 4 Cbei_4704 53 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150016648 Common - protein of unknown function DUF47 Cbei_1774 67 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 150019161 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_4349 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150016950 Nonpathogen - hypothetical protein Cbei_2081 3 None None None 150018154 Common - ABC transporter related Cbei_3325 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150019695 Common - methyltransferase small Cbei_4887 84 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 150017860 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_3019 242 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 150016033 Common - radical SAM enzyme, Cfr family Cbei_1149 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 150016128 Common - K+ potassium transporter Cbei_1244 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 150018653 Common - peptidase C1A, papain Cbei_3836 25 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 150016091 Common rpsO 30S ribosomal protein S15 Cbei_1207 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 150016581 Common - hemolysin A Cbei_1707 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 150017458 Common - hypothetical protein Cbei_2600 2 None None None 150015298 Common upp uracil phosphoribosyltransferase Cbei_0408 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 150017719 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Cbei_2871 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 150019751 Common - response regulator receiver protein Cbei_4943 56 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150017495 Nonpathogen - hypothetical protein Cbei_2639 2 None None None 150016780 Common - hypothetical protein Cbei_1908 14 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 150019722 Common - PTS system, mannose/fructose/sorbose family, IIA subunit Cbei_4914 88 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150015147 Common - BAAT/Acyl-CoA thioester hydrolase-like protein Cbei_0255 16 None None None 150018137 Common - ABC transporter related Cbei_3308 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150019828 Common - transcriptional regulator, RpiR family Cbei_5020 24 COG1737 RpiR, Transcriptional regulators Transcription 150017520 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_2665 37 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150016322 Common - binding-protein-dependent transport systems inner membrane component Cbei_1442 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150016523 Common - hypothetical protein Cbei_1647 5 None None None 150019353 Common - acyl-CoA dehydrogenase domain protein Cbei_4542 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150019358 Common - oxidoreductase domain protein Cbei_4547 187 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150015853 Common - sugar isomerase (SIS) Cbei_0967 57 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 150018112 Common - NUDIX hydrolase Cbei_3282 105 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 150018889 Common - methyl-accepting chemotaxis sensory transducer Cbei_4077 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017503 Common - acetolactate synthase, small subunit Cbei_2647 131 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 150019450 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_4640 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150016885 Common - DNA polymerase, beta domain protein region Cbei_2013 5 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 150017886 Common - methyl-accepting chemotaxis sensory transducer Cbei_3045 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018821 Common - hypothetical protein Cbei_4009 10 None None None 150015172 Nonpathogen - hypothetical protein Cbei_0282 1 None None None 150016255 Common - phage integrase family protein Cbei_1373 10 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150016432 Common - hypothetical protein Cbei_1556 1 None None None 150016565 Common - hypothetical protein Cbei_1691 9 None None None 150018474 Nonpathogen - hypothetical protein Cbei_3653 1 None None None 150017655 Common - hypothetical protein Cbei_2803 3 None None None 150019141 Common - hypothetical protein Cbei_4329 1 None None None 150019866 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_5058 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019277 Common - methyl-accepting chemotaxis sensory transducer Cbei_4466 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017109 Common - Alcohol dehydrogenase, zinc-binding domain protein Cbei_2243 185 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 150019651 Common - Xylose isomerase domain protein TIM barrel Cbei_4842 39 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 150015323 Common secA preprotein translocase subunit SecA Cbei_0433 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 150017899 Common - transcriptional regulator, MarR family Cbei_3059 136 COG1846 MarR, Transcriptional regulators Transcription 150015395 Common - Radical SAM domain protein Cbei_0505 61 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150017783 Nonpathogen - hypothetical protein Cbei_2939 1 None None None 150019313 Common - transport system permease protein Cbei_4502 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150015577 Nonpathogen - hypothetical protein Cbei_0689 1 None None None 150018537 Common - hypothetical protein Cbei_3718 5 None None None 150018408 Common - alpha/beta hydrolase fold Cbei_3584 24 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150017158 Nonpathogen - hypothetical protein Cbei_2296 1 None None None 150018041 Nonpathogen - hypothetical protein Cbei_3209 1 None None None 150018095 Common - small acid-soluble spore protein, alpha/beta type Cbei_3264 14 None None None 150015788 Common - hypothetical protein Cbei_0902 3 None None None 150018709 Common - transcriptional regulator, MarR family Cbei_3893 33 COG1846 MarR, Transcriptional regulators Transcription 150015092 Common - protein of unknown function DUF147 Cbei_0200 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 150019365 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_4554 107 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150016129 Common - hypothetical protein Cbei_1245 1 None None None 150018854 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Cbei_4042 111 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150019678 Common - Transketolase, central region Cbei_4870 230 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 150016423 Common aspS aspartyl-tRNA synthetase Cbei_1545 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017397 Common - Radical SAM domain protein Cbei_2539 158 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 150015036 Common rpoB DNA-directed RNA polymerase subunit beta Cbei_0144 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 150016986 Common - two component transcriptional regulator, winged helix family Cbei_2117 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015226 Common - PTS system, glucitol/sorbitol-specific, IIC subunit Cbei_0336 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 150018048 Nonpathogen - hypothetical protein Cbei_3216 1 None None None 150019758 Common - conserved hypothetical protein 103 Cbei_4950 60 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 150018589 Common - transcriptional antiterminator, BglG Cbei_3770 25 COG3711 BglG, Transcriptional antiterminator Transcription 150015843 Common - phosphotransferase system PTS, sorbose-specific IIC subunit Cbei_0957 40 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150015892 Common pyrE orotate phosphoribosyltransferase Cbei_1006 114 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 150017172 Common - cobyrinic acid a,c-diamide synthase Cbei_2310 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 150018027 Common - hypothetical protein Cbei_3195 5 None None None 150016760 Nonpathogen - hypothetical protein Cbei_1887 1 None None None 150018287 Common - SMC domain protein Cbei_3460 36 COG3910 COG3910, Predicted ATPase General function prediction only 150015227 Common - PTS system, glucitol/sorbitol-specific, IIBC subunit Cbei_0337 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 150018129 Common - ABC transporter related Cbei_3300 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150016291 Common - hypothetical protein Cbei_1411 1 None None None 150015099 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Cbei_0207 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 150018878 Common - hypothetical protein Cbei_4066 6 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 150015976 Nonpathogen - hypothetical protein Cbei_1091 2 None None None 150016472 Common - pyrimidine regulatory protein PyrR Cbei_1596 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 150018221 Common - phage-like element pbsx protein XkdQ Cbei_3393 4 None None None 150018695 Common - binding-protein-dependent transport systems inner membrane component Cbei_3879 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150016373 Common - hypothetical protein Cbei_1494 6 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 150015260 Common - peptidase U62, modulator of DNA gyrase Cbei_0370 158 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 150015566 Common - transcriptional regulator, AraC family Cbei_0678 142 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015828 Common - CobB/CobQ domain protein glutamine amidotransferase Cbei_0942 51 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 150019538 Common - ABC transporter related Cbei_4728 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150015388 Common - cell division topological specificity factor MinE Cbei_0498 62 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 150015267 Common - O-sialoglycoprotein endopeptidase Cbei_0377 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 150017589 Common - Na+/H+ antiporter Cbei_2736 97 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 150019706 Common - hypothetical protein Cbei_4898 6 None None None 150016938 Common - Glutaredoxin-like protein Cbei_2068 5 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 150018146 Common - major facilitator superfamily MFS_1 Cbei_3317 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019133 Common - single-stranded-DNA-specific exonuclease RecJ Cbei_4321 197 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 150019115 Common - flagellar motor switch protein FliM Cbei_4303 108 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 150016754 Common - glucose-inhibited division protein A Cbei_1881 28 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 150015409 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cbei_0519 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150018211 Common - conserved repeat domain Cbei_3383 36 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 150016975 Common - histidinol-phosphatase Cbei_2106 34 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 150018421 Common - glutamate racemase Cbei_3599 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 150018132 Common - diguanylate cyclase/phosphodiesterase Cbei_3303 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 150016532 Common - Baseplate J family protein Cbei_1656 28 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150016181 Common - hypothetical protein Cbei_1299 7 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 150015971 Nonpathogen - hypothetical protein Cbei_1086 1 None None None 150019582 Common - glycosyltransferase 36 Cbei_4773 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 150016437 Common - hypothetical protein Cbei_1561 3 None None None 150019899 Common - cysteine desulfurase family protein Cbei_5091 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150016025 Common gmk guanylate kinase Cbei_1141 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 150016617 Common - protein of unknown function DUF45 Cbei_1743 140 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 150018024 Common - hypothetical protein Cbei_3192 2 None None None 150014964 Common - DNA-3-methyladenine glycosylase Cbei_0072 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 150017357 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_2499 19 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 150018011 Common - Lysine exporter protein (LYSE/YGGA) Cbei_3178 69 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 150017835 Common - NADH dehydrogenase (ubiquinone), 30 kDa subunit Cbei_2994 174 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 150018934 Common - hypothetical protein Cbei_4122 141 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 150017567 Common - hydrolase of alpha/beta superfamily Cbei_2714 24 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 150017125 Nonpathogen - hypothetical protein Cbei_2260 1 None None None 150017896 Common - BFD domain protein (2Fe-2S)-binding domain protein Cbei_3056 13 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 150019745 Common - Amidohydrolase 3 Cbei_4937 76 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 150019328 Common - N-acetyl-gamma-glutamyl-phosphate reductase Cbei_4517 219 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 150017031 Common - transcriptional regulator, XRE family Cbei_2162 19 COG1476 COG1476, Predicted transcriptional regulators Transcription 150017558 Common - RDD domain containing protein Cbei_2704 4 None None None 150017130 Common - hypothetical protein Cbei_2267 2 None None None 150018978 Common - protein of unknown function DUF214 Cbei_4166 17 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 150019408 Nonpathogen - hypothetical protein Cbei_4598 1 None None None 150018962 Common - putative transcriptional regulator, AsnC family Cbei_4150 100 COG1522 Lrp, Transcriptional regulators Transcription 150017518 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_2663 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150017869 Common - major facilitator superfamily MFS_1 Cbei_3028 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018415 Common - Ketopantoate reductase ApbA/PanE, N-terminal domain protein Cbei_3592 5 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 150018773 Common - methyl-accepting chemotaxis sensory transducer Cbei_3961 163 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017113 Common - ribosomal RNA adenine dimethylase Cbei_2248 45 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 150016275 Common - Radical SAM domain protein Cbei_1394 96 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150017006 Common - putative cell wall binding repeat-containing protein Cbei_2137 5 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016336 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_1456 8 None None None 150018731 Nonpathogen - hypothetical protein Cbei_3917 1 None None None 150015411 Nonpathogen - hypothetical protein Cbei_0521 1 None None None 150017966 Common - cytidine deaminase Cbei_3128 113 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 150016138 Common - YjlA Cbei_1255 11 None None None 150018314 Nonpathogen - hypothetical protein Cbei_3489 1 None None None 150016352 Common - nitroreductase family protein Cbei_1472 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 150016230 Nonpathogen - hypothetical protein Cbei_1348 1 None None None 150015779 Common - hypothetical protein Cbei_0893 1 None None None 150016790 Common - phosphotransferase system, EIIC Cbei_1918 44 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150018514 Common - cobalt transport protein CbiM Cbei_3695 84 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 150015038 Common rpsL 30S ribosomal protein S12 Cbei_0146 227 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 150019715 Common - glycogen/starch/alpha-glucan phosphorylase Cbei_4907 148 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 150017687 Common - plasmid pRiA4b ORF-3 family protein Cbei_2837 21 None None None 150016870 Nonpathogen - hypothetical protein Cbei_1998 5 None None None 150017775 Common - hypothetical protein Cbei_2930 16 None None None 150017334 Common - transcriptional regulator, TetR family Cbei_2475 109 COG1309 AcrR, Transcriptional regulator Transcription 150015390 Common - hypothetical protein Cbei_0500 1 None None None 150016866 Common - ABC transporter related Cbei_1994 239 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 150016875 Common - nitrogenase molybdenum-iron protein beta chain Cbei_2003 58 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150018921 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cbei_4109 13 COG5015 COG5015, Uncharacterized conserved protein Function unknown 150017102 Nonpathogen - hypothetical protein Cbei_2235 1 None None None 150018844 Common - Beta-ketoacyl-acyl-carrier-protein synthase I Cbei_4032 188 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150016444 Common - Sporulation protein YtxC Cbei_1568 13 None None None 150015211 Common - 3-hydroxybutyryl-CoA dehydratase Cbei_0321 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150015356 Common - transcriptional regulator, DeoR family Cbei_0466 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150018675 Common - transcriptional regulator, TetR family Cbei_3858 26 COG1309 AcrR, Transcriptional regulator Transcription 150018088 Common - Rubrerythrin Cbei_3257 5 COG1633 COG1633, Uncharacterized conserved protein Function unknown 150017988 Nonpathogen - hypothetical protein Cbei_3153 1 None None None 150018018 Nonpathogen - hypothetical protein Cbei_3186 1 None None None 150019197 Common - putative cell wall binding repeat-containing protein Cbei_4386 4 None None None 150015585 Common - cellobiose/arbutin/salicin-specific PTS system components IIBC Cbei_0699 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150018985 Common - ABC transporter related Cbei_4173 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150015125 Common - 4-alpha-glucanotransferase Cbei_0233 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 150015341 Common - oligogalacturonide transporter Cbei_0451 64 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150018957 Common - inner-membrane translocator Cbei_4145 106 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 150017206 Nonpathogen - hypothetical protein Cbei_2344 1 None None None 150015307 Common - F0F1 ATP synthase subunit gamma Cbei_0417 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 150016715 Common - transcriptional regulator, DeoR family Cbei_1842 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150017584 Common - NADH:flavin oxidoreductase/NADH oxidase Cbei_2731 229 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150019689 Common - hexapeptide transferase family protein Cbei_4881 207 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 150016882 Common - putative transcriptional regulator, AsnC family Cbei_2010 56 COG1522 Lrp, Transcriptional regulators Transcription 150019156 Common - sodium:dicarboxylate symporter Cbei_4344 159 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 150015376 Common - aminoacyl-histidine dipeptidase Cbei_0486 66 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 150018897 Common - transcriptional regulator, GntR family Cbei_4085 135 COG1802 GntR, Transcriptional regulators Transcription 150015026 Common - protein of unknown function DUF901 Cbei_0134 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 150019525 Nonpathogen - hypothetical protein Cbei_4715 1 None None None 150015622 Nonpathogen - hypothetical protein Cbei_0736 1 None None None 150019501 Common - polysaccharide biosynthesis protein Cbei_4691 29 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150015731 Common era GTP-binding protein Era Cbei_0845 233 COG1159 Era, GTPase General function prediction only 150018344 Common - Hydantoinase/oxoprolinase Cbei_3519 112 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150014982 Common - MazG family protein Cbei_0090 157 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 150014921 Common carB carbamoyl phosphate synthase large subunit Cbei_0029 238 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 150016280 Common - glycosyl transferase, family 4 Cbei_1400 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 150019196 Common - putative cell wall binding repeat-containing protein Cbei_4385 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015468 Common - phospholipid/glycerol acyltransferase Cbei_0579 120 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150016669 Common - dihydrodipicolinate synthase Cbei_1796 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150019814 Common - LrgB family protein Cbei_5006 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 150016922 Nonpathogen - hypothetical protein Cbei_2052 4 None None None 150015010 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_0118 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 150018163 Nonpathogen - hypothetical protein Cbei_3334 1 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 150019234 Common - Radical SAM domain protein Cbei_4423 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 150017359 Common - Glycerol-1-phosphate dehydrogenase (NAD(P)(+)) Cbei_2501 58 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 150019592 Common - ATP-dependent metalloprotease FtsH Cbei_4783 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150015218 Common groES co-chaperonin GroES Cbei_0328 213 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 150018750 Nonpathogen - hypothetical protein Cbei_3938 1 None None None 150019523 Common - glycosyl transferase, group 1 Cbei_4713 32 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150016195 Common - thiamine biosynthesis/tRNA modification protein ThiI Cbei_1313 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 150016418 Common - (p)ppGpp synthetase I, SpoT/RelA Cbei_1540 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 150018832 Common - response regulator receiver protein Cbei_4020 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150019609 Common - extracellular solute-binding protein, family 3 Cbei_4800 171 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150019166 Common - iron-containing alcohol dehydrogenase Cbei_4354 177 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150017697 Common - hypothetical protein Cbei_2847 1 None None None 150019912 Common rpmH 50S ribosomal protein L34 Cbei_5104 187 None None None 150015618 Common - extracellular solute-binding protein, family 1 Cbei_0732 117 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019237 Common - D-galactose-binding periplasmic protein precursor Cbei_4426 73 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015663 Common - Glutathione peroxidase Cbei_0777 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 150015319 Common - helicase, RecD/TraA family Cbei_0429 137 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 150017389 Common - GtrA family protein Cbei_2531 2 COG2246 COG2246, Predicted membrane protein Function unknown 150017422 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase Cbei_2564 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 150016889 Common - Patatin Cbei_2017 34 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 150017931 Common - MATE efflux family protein Cbei_3092 135 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150018655 Common - GCN5-related N-acetyltransferase Cbei_3838 8 COG0456 RimI, Acetyltransferases General function prediction only 150016802 Common - hypothetical protein Cbei_1930 1 None None None 150018995 Common - CheA signal transduction histidine kinase Cbei_4183 150 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 150016650 Nonpathogen - hypothetical protein Cbei_1776 2 None None None 150018258 Nonpathogen - hypothetical protein Cbei_3430 4 None None None 150015658 Common - alpha-xylosidase YicI Cbei_0772 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 150015542 Common - polysaccharide deacetylase Cbei_0653 96 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150017318 Common - 5-keto-4-deoxyuronate isomerase Cbei_2458 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 150015770 Nonpathogen - hypothetical protein Cbei_0884 1 None None None 150018701 Common - secretion protein HlyD family protein Cbei_3885 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150015531 Common - putative transcriptional regulator, XRE family Cbei_0642 18 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 150016061 Common - hypothetical protein Cbei_1177 70 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 150018931 Common - para-aminobenzoate synthase, subunit I Cbei_4119 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 150015017 Common - glutaredoxin-like protein, YruB-family Cbei_0125 85 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 150018479 Common - NAD-dependent epimerase/dehydratase Cbei_3659 224 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150019227 Common - metal dependent phosphohydrolase Cbei_4416 30 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 150016223 Common - putative transcriptional regulator, XRE family Cbei_1341 1 COG3655 COG3655, Predicted transcriptional regulator Transcription 150016342 Nonpathogen - hypothetical protein Cbei_1462 1 None None None 150018284 Nonpathogen - hypothetical protein Cbei_3457 1 None None None 150018929 Common - hypothetical protein Cbei_4117 29 COG1160 COG1160, Predicted GTPases General function prediction only 150015627 Common - protein of unknown function DUF988 Cbei_0741 20 COG4708 COG4708, Predicted membrane protein Function unknown 150018215 Nonpathogen - hypothetical protein Cbei_3387 1 None None None 150019886 Nonpathogen - hypothetical protein Cbei_5078 1 None None None 150015277 Common - Spore coat protein CotS Cbei_0387 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 150015237 Common - transcriptional regulator, HxlR family Cbei_0347 134 COG1733 COG1733, Predicted transcriptional regulators Transcription 150018120 Common - GCN5-related N-acetyltransferase Cbei_3291 37 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150016848 Common - transcriptional regulator, TetR family Cbei_1976 10 COG1309 AcrR, Transcriptional regulator Transcription 150017523 Common - hypothetical protein Cbei_2668 9 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 150018602 Common - methyl-accepting chemotaxis sensory transducer Cbei_3783 81 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019385 Common - chorismate synthase Cbei_4574 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 150019667 Common uvrC excinuclease ABC subunit C Cbei_4859 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 150018609 Common - methyl-accepting chemotaxis sensory transducer Cbei_3790 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015620 Common - binding-protein-dependent transport systems inner membrane component Cbei_0734 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150015868 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Cbei_0982 161 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 150017197 Common - Heavy metal transport/detoxification protein Cbei_2335 3 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150015944 Common - phosphoribosylglycinamide formyltransferase Cbei_1058 218 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 150016587 Common - hemerythrin-like metal-binding protein Cbei_1713 39 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150017300 Nonpathogen - hypothetical protein Cbei_2440 3 None None None 150017577 Common - ATP-dependent DNA helicase replicase Cbei_2724 69 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 150016365 Common - GCN5-related N-acetyltransferase Cbei_1485 23 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 150018177 Common - MaoC domain protein dehydratase Cbei_3349 106 COG2030 MaoC, Acyl dehydratase Lipid metabolism 150019006 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Cbei_4194 92 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 150019302 Common - thiW protein Cbei_4491 16 COG4732 COG4732, Predicted membrane protein Function unknown 150017667 Common - transcription activator, effector binding Cbei_2816 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015405 Common - cell envelope-related transcriptional attenuator Cbei_0515 65 COG1316 LytR, Transcriptional regulator Transcription 150015872 Common - integral membrane protein MviN Cbei_0986 175 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 150019371 Common - PTS system fructose subfamily IIA component Cbei_4560 28 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150016951 Common - Adenylosuccinate synthase Cbei_2082 229 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 150015534 Common - ATPase AAA-2 domain protein Cbei_0645 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150017542 Common - GCN5-related N-acetyltransferase Cbei_2687 7 COG0456 RimI, Acetyltransferases General function prediction only 150017200 Common - hemerythrin-like metal-binding protein Cbei_2338 48 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150019335 Common - NADPH-dependent FMN reductase Cbei_4524 40 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150015005 Common - dTMP kinase Cbei_0113 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 150018332 Common - type I phosphodiesterase/nucleotide pyrophosphatase Cbei_3507 20 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 150017208 Nonpathogen - hypothetical protein Cbei_2346 1 None None None 150017230 Common - GCN5-related N-acetyltransferase Cbei_2368 24 COG0456 RimI, Acetyltransferases General function prediction only 150018671 Common - hypothetical protein Cbei_3854 10 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150018892 Common - histidine triad (HIT) protein Cbei_4080 15 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 150017977 Nonpathogen - hypothetical protein Cbei_3139 5 None None None 150016172 Common - hypothetical protein Cbei_1290 1 None None None 150017263 Common - transglutaminase domain protein Cbei_2403 12 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 150017770 Common - DEAD/DEAH box helicase domain protein Cbei_2925 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150015805 Common - putative cell wall binding repeat-containing protein Cbei_0919 8 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018582 Common - periplasmic binding protein Cbei_3763 60 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150019100 Common - IstB domain protein ATP-binding protein Cbei_4288 109 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150017777 Common - Na+/H+ antiporter NhaA Cbei_2932 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 150017124 Common - beta-lactamase domain protein Cbei_2259 160 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 150019247 Common - diguanylate cyclase/phosphodiesterase Cbei_4436 172 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150019253 Common - glycoside hydrolase, clan GH-D Cbei_4442 44 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 150017545 Nonpathogen - GCN5-related N-acetyltransferase Cbei_2690 1 COG3393 COG3393, Predicted acetyltransferase General function prediction only 150015487 Common pgk phosphoglycerate kinase Cbei_0598 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 150018617 Common - formate dehydrogenase family accessory protein FdhD Cbei_3798 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 150015424 Common - two component transcriptional regulator, winged helix family Cbei_0534 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017174 Common cbiD cobalt-precorrin-6A synthase Cbei_2312 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 150018638 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Cbei_3820 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 150015508 Nonpathogen - hypothetical protein Cbei_0619 4 COG5583 COG5583, Uncharacterized small protein Function unknown 150017753 Common - N-acetylgalactosamine-specific PTS system transporter subunit IID Cbei_2906 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150017608 Common - biotin/lipoyl attachment domain-containing protein Cbei_2755 155 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 150019495 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_4685 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150017936 Common - cobalt transport protein Cbei_3097 27 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150017073 Common - transcriptional regulator, TetR family Cbei_2204 24 COG1309 AcrR, Transcriptional regulator Transcription 150019803 Common - hypothetical protein Cbei_4995 9 None None None 150019026 Common - Fimbrial assembly family protein Cbei_4214 4 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 150015074 Common - ABC transporter related Cbei_0182 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150019439 Common - polysaccharide biosynthesis protein CapD Cbei_4629 213 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150018785 Common - putative transcriptional regulator, MerR family Cbei_3973 103 COG0789 SoxR, Predicted transcriptional regulators Transcription 150017167 Nonpathogen - hypothetical protein Cbei_2305 1 None None None 150015675 Common - hypothetical protein Cbei_0789 3 None None None 150015912 Common - protein of unknown function DUF1113 Cbei_1026 12 COG4905 COG4905, Predicted membrane protein Function unknown 150019033 Common - putative cell wall binding repeat-containing protein Cbei_4221 2 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015681 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_0795 32 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150019473 Common - Protein of unknown function DUF1980 Cbei_4663 18 COG3689 COG3689, Predicted membrane protein Function unknown 150019430 Common - sugar transferase Cbei_4620 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150015704 Common - E1-E2 ATPase-associated domain protein Cbei_0818 154 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150017830 Common - NADH-ubiquinone oxidoreductase, chain 4L Cbei_2989 138 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 150017216 Common - Auxin Efflux Carrier Cbei_2354 18 COG0679 COG0679, Predicted permeases General function prediction only 150017323 Common - cobalamin synthesis protein, P47K Cbei_2463 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 150016459 Common - stage V sporulation protein E Cbei_1583 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150017135 Common - prophage antirepressor Cbei_2272 33 COG3617 COG3617, Prophage antirepressor Transcription 150016723 Common - FeS assembly protein SufD Cbei_1850 183 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 150018736 Common - Phosphoglycerate mutase Cbei_3922 108 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150018184 Common - methyl-accepting chemotaxis sensory transducer Cbei_3356 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016264 Common - putative symporter YidK Cbei_1383 120 COG4146 COG4146, Predicted symporter General function prediction only 150019684 Common - holo-acyl-carrier-protein synthase Cbei_4876 79 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 150017380 Common - ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent Cbei_2522 53 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 150016903 Nonpathogen - hypothetical protein Cbei_2033 1 None None None 150016673 Common hslO Hsp33-like chaperonin Cbei_1800 135 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 150017642 Common - protein of unknown function DUF534 Cbei_2790 54 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 150015864 Common - major facilitator superfamily MFS_1 Cbei_0978 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150017089 Common - MATE efflux family protein Cbei_2222 157 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150015619 Common - binding-protein-dependent transport systems inner membrane component Cbei_0733 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150017374 Common - response regulator receiver protein Cbei_2516 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150019646 Common - Mandelate racemase/muconate lactonizing protein Cbei_4837 107 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 150019077 Common - flagellar protein export ATPase FliI Cbei_4265 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 150016746 Common - DNA topoisomerase III Cbei_1873 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150018969 Common - Radical SAM domain protein Cbei_4157 106 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 150017963 Common deoD purine nucleoside phosphorylase Cbei_3125 83 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 150019563 Common - dTDP-glucose 4,6-dehydratase Cbei_4754 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 150019411 Common - hypothetical protein Cbei_4601 4 None None None 150015122 Common - extracellular solute-binding protein, family 1 Cbei_0230 43 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016850 Common - putative chlorohydrolase/aminohydrolase Cbei_1978 143 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 150017826 Common - two component transcriptional regulator, winged helix family Cbei_2985 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015799 Nonpathogen - hypothetical protein Cbei_0913 2 None None None 150019614 Common - 6-phospho-beta-glucosidase Cbei_4805 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150015590 Common - transcriptional regulator, XRE family Cbei_0704 38 COG1476 COG1476, Predicted transcriptional regulators Transcription 150014971 Common - purine operon repressor Cbei_0079 31 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 150014995 Common - putative TIM-barrel protein, nifR3 family Cbei_0103 216 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 150017418 Common - GAF domain-containing protein Cbei_2560 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 150016346 Common - putative oxidoreductase Cbei_1466 185 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150017821 Nonpathogen - hypothetical protein Cbei_2979 1 COG2155 COG2155, Uncharacterized conserved protein Function unknown 150017927 Common - iron dependent repressor Cbei_3088 71 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 150018306 Common - transcriptional regulator, MarR family Cbei_3480 27 COG1846 MarR, Transcriptional regulators Transcription 150019150 Common - cytidyltransferase-related domain Cbei_4338 134 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 150019853 Common - ABC transporter related Cbei_5045 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150016392 Nonpathogen - hypothetical protein Cbei_1514 1 None None None 150017789 Common - hypothetical protein Cbei_2946 4 None None None 150019108 Common - flagellar assembly protein FliW Cbei_4296 39 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 150015551 Common - putative oxidoreductase Cbei_0662 185 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150016450 Common pheT phenylalanyl-tRNA synthetase subunit beta Cbei_1574 246 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 150016895 Nonpathogen - hypothetical protein Cbei_2023 2 None None None 150017272 Common - NUDIX hydrolase Cbei_2412 15 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150019484 Common - glycoside hydrolase, family 3 domain protein Cbei_4674 101 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150018481 Common - 60 kDa inner membrane insertion protein Cbei_3661 84 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 150017885 Nonpathogen - hypothetical protein Cbei_3044 1 None None None 150018717 Common - GCN5-related N-acetyltransferase Cbei_3901 10 COG3981 COG3981, Predicted acetyltransferase General function prediction only 150019872 Common - hypothetical protein Cbei_5064 6 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 150019654 Common - PTS system, beta-glucoside-specific IIABC subunit Cbei_4846 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150017014 Common - ABC transporter related Cbei_2145 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150016546 Common - hypothetical protein Cbei_1670 35 None None None 150015435 Common - Transketolase domain protein Cbei_0545 222 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 150018509 Common - ABC transporter related Cbei_3690 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150018293 Common - transcriptional regulator, LysR family Cbei_3466 189 COG0583 LysR, Transcriptional regulator Transcription 150014981 Common - polysaccharide biosynthesis protein Cbei_0089 42 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150018190 Common - putative cell wall binding repeat-containing protein Cbei_3362 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016271 Common - methyl-accepting chemotaxis sensory transducer Cbei_1390 29 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016813 Common - NMT1/THI5-like protein Cbei_1941 69 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150015605 Common - Integrase, catalytic region Cbei_0719 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 150017591 Common - transcriptional antiterminator, BglG Cbei_2738 49 COG3711 BglG, Transcriptional antiterminator Transcription 150017570 Common - transcription activator, effector binding Cbei_2717 13 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 150019072 Common - protein of unknown function DUF1078 domain protein Cbei_4260 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 150015790 Nonpathogen - hypothetical protein Cbei_0904 1 None None None 150018628 Common - hypothetical protein Cbei_3809 4 None None None 150018013 Common - transcriptional regulator, LysR family Cbei_3181 176 COG0583 LysR, Transcriptional regulator Transcription 150018960 Common - Alanine racemase Cbei_4148 129 COG1609 PurR, Transcriptional regulators Transcription 150016018 Common engA GTP-binding protein EngA Cbei_1134 227 COG1160 COG1160, Predicted GTPases General function prediction only 150018727 Common - pentapeptide repeat protein Cbei_3913 84 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150019543 Common - hypothetical protein Cbei_4733 2 None None None 150018973 Common - methyl-accepting chemotaxis sensory transducer Cbei_4161 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017516 Common - hypothetical protein Cbei_2661 2 None None None 150016404 Common - ErfK/YbiS/YcfS/YnhG family protein Cbei_1526 12 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150017048 Nonpathogen - hypothetical protein Cbei_2179 1 None None None 150017406 Common - protein of unknown function DUF815 Cbei_2548 90 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 150016131 Common - hypothetical protein Cbei_1248 15 None None None 150018794 Nonpathogen - protein of unknown function DUF6, transmembrane Cbei_3982 6 None None None 150018816 Common - response regulator receiver Cbei_4004 220 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 150016804 Common - iron-containing alcohol dehydrogenase Cbei_1932 168 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 150016968 Common - sigma54 specific transcriptional regulator, Fis family Cbei_2099 219 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150018157 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_3328 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150014894 Common - DNA polymerase III subunit beta Cbei_0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 150019414 Common - methyl-accepting chemotaxis sensory transducer Cbei_4604 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016298 Nonpathogen - hypothetical protein Cbei_1418 1 None None None 150017045 Common - hypothetical protein Cbei_2176 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 150019693 Common - transcriptional regulator, AbrB family Cbei_4885 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150016164 Common - Di-trans-poly-cis-decaprenylcistransferase Cbei_1282 228 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 150017378 Common - MATE efflux family protein Cbei_2520 160 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150018475 Common - response regulator receiver protein Cbei_3654 5 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150015693 Common - integral membrane sensor signal transduction histidine kinase Cbei_0807 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017616 Common - putative transcriptional regulator, AsnC family Cbei_2763 164 COG1522 Lrp, Transcriptional regulators Transcription 150019763 Common - hypothetical protein Cbei_4955 1 COG1633 COG1633, Uncharacterized conserved protein Function unknown 150017390 Common - peptidase U61, LD-carboxypeptidase A Cbei_2532 87 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 150016559 Common - hypothetical protein Cbei_1685 1 None None None 150018182 Common - NADPH-dependent FMN reductase Cbei_3354 48 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150016054 Common rnc ribonuclease III Cbei_1170 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 150015501 Common - Nitrogenase Cbei_0612 58 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150019792 Common - glycoside hydrolase, family 4 Cbei_4984 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150017279 Common - polyphosphate kinase Cbei_2419 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 150017845 Common - prolipoprotein diacylglyceryl transferase Cbei_3004 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150017870 Nonpathogen - hypothetical protein Cbei_3029 1 None None None 150019625 Common - hemerythrin-like metal-binding protein Cbei_4816 36 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150015118 Common - Ribulose-phosphate 3-epimerase Cbei_0226 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150017005 Common - helix-turn-helix- domain containing protein, AraC type Cbei_2136 94 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016906 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Cbei_2036 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150019219 Common - carboxynorspermidine decarboxylase Cbei_4408 73 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 150015931 Common - protein of unknown function DUF107 Cbei_1045 2 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150019621 Nonpathogen - hypothetical protein Cbei_4812 11 None None None 150015331 Common - protein of unknown function DUF6, transmembrane Cbei_0441 116 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150018414 Common - lysyl-tRNA synthetase Cbei_3591 246 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150017292 Common - phosphoribosylpyrophosphate synthetase Cbei_2432 227 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 150014937 Nonpathogen - hypothetical protein Cbei_0045 2 None None None 150015160 Nonpathogen - Accessory gene regulator B Cbei_0269 1 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150015461 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Cbei_0572 154 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 150017328 Common - glycogen debranching enzyme GlgX Cbei_2468 163 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 150019131 Common - flavodoxin Cbei_4319 28 COG0716 FldA, Flavodoxins Energy production and conversion 150015089 Common - Tetratricopeptide TPR_2 repeat protein Cbei_0197 1 COG4105 ComL, DNA uptake lipoprotein General function prediction only 150018249 Common - hypothetical protein Cbei_3421 8 None None None 150019770 Common - response regulator receiver protein Cbei_4962 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150019645 Common - transcriptional regulator, GntR family Cbei_4836 60 COG2188 PhnF, Transcriptional regulators Transcription 150017509 Common - 3-oxoacid CoA-transferase, A subunit Cbei_2654 109 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 150019205 Nonpathogen - hypothetical protein Cbei_4394 3 None None None 150016144 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Cbei_1262 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 150015493 Common - NMT1/THI5-like protein Cbei_0604 111 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150016621 Common - DEAD/DEAH box helicase domain protein Cbei_1747 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150016694 Common - DEAD/DEAH box helicase domain protein Cbei_1821 229 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150017069 Common - mannonate dehydratase Cbei_2200 59 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 150016610 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_1736 68 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150015600 Common - protein of unknown function DUF956 Cbei_0714 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 150019146 Common - ABC transporter related Cbei_4334 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 150015951 Common - hypothetical protein Cbei_1065 1 None None None 150015270 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_0380 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150019825 Common - PTS system, glucose subfamily, IIA subunit Cbei_5017 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 150014988 Common - hypothetical protein Cbei_0096 235 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 150019293 Common uvsE putative UV damage endonuclease Cbei_4482 34 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 150017060 Common - transcriptional regulator, RpiR family Cbei_2191 106 COG1737 RpiR, Transcriptional regulators Transcription 150017879 Common - peptidase, membrane zinc metallopeptidase, putative Cbei_3038 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 150015190 Common - hypothetical protein Cbei_0300 9 None None None 150017867 Common - Heavy metal transport/detoxification protein Cbei_3026 18 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 150017051 Common - ferredoxin--NADP(+) reductase subunit alpha Cbei_2182 93 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150019782 Common - glycoside hydrolase, family 3 domain protein Cbei_4974 104 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150018238 Common - protein of unknown function DUF6, transmembrane Cbei_3410 108 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 150015812 Common - hypothetical protein Cbei_0926 3 None None None 150018612 Common - molybdenum cofactor biosynthesis protein A Cbei_3793 201 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 150015752 Common - 2-hydroxyacid dehydrogenase Cbei_0866 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 150015821 Common - binding-protein-dependent transport systems inner membrane component Cbei_0935 173 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150016002 Common - cell division protein FtsZ Cbei_1118 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 150016992 Common - hypothetical protein Cbei_2123 11 None None None 150015455 Common - putative serine protein kinase, PrkA Cbei_0566 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 150016662 Common - polysaccharide deacetylase Cbei_1789 129 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150017367 Common - 3D domain protein Cbei_2509 24 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150017858 Common - beta-lactamase domain protein Cbei_3017 89 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150019110 Common - flagellar hook-associated protein FlgK Cbei_4298 127 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 150019309 Common - L-serine dehydratase, iron-sulfur-dependent, alpha subunit Cbei_4498 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 150019126 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Cbei_4314 31 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 150019755 Common - sigma-K factor processing regulatory protein BofA Cbei_4947 2 None None None 150015081 Common - fumarate hydratase Cbei_0189 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 150018560 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cbei_3741 176 COG0546 Gph, Predicted phosphatases General function prediction only 150017815 Common - cell division ATP-binding protein FtsE Cbei_2972 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 150018903 Nonpathogen - hypothetical protein Cbei_4091 1 None None None 150015106 Common - 3-isopropylmalate dehydratase, large subunit Cbei_0214 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 150016622 Common - transcriptional regulator, BadM/Rrf2 family Cbei_1748 152 COG1959 COG1959, Predicted transcriptional regulator Transcription 150018195 Common - putative sugar-specific permease, SgaT/UlaA Cbei_3367 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 150019729 Nonpathogen - Ion transport 2 domain protein Cbei_4921 1 None None None 150019740 Common - binding-protein-dependent transport systems inner membrane component Cbei_4932 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150019007 Nonpathogen - hypothetical protein Cbei_4195 1 None None None 150014976 Common - integral membrane sensor signal transduction histidine kinase Cbei_0084 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015712 Common - hypothetical protein Cbei_0826 1 None None None 150017297 Common - protein of unknown function DUF503 Cbei_2437 28 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 150018296 Common - histidine kinase Cbei_3469 215 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150017942 Common - peptidase M56, BlaR1 Cbei_3103 27 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 150017842 Common - nitrite and sulphite reductase 4Fe-4S region Cbei_3001 133 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 150016017 Common - protein of unknown function DUF512 Cbei_1133 31 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 150015978 Common - hypothetical protein Cbei_1093 3 None None None 150016081 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Cbei_1197 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 150015046 Common rplB 50S ribosomal protein L2 Cbei_0154 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 150017340 Common - glycoside hydrolase, family 25 Cbei_2481 41 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150019479 Common - glycoside hydrolase, family 1 Cbei_4669 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150017562 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_2708 25 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150017332 Common - integral membrane sensor signal transduction histidine kinase Cbei_2473 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150018768 Nonpathogen - hypothetical protein Cbei_3956 1 None None None 150015564 Nonpathogen - transposase Cbei_0676 12 None None None 150019851 Common - inner-membrane translocator Cbei_5043 170 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 150017440 Common - hypothetical protein Cbei_2582 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150018394 Common - FMN-binding domain protein Cbei_3570 57 COG0348 NapH, Polyferredoxin Energy production and conversion 150015660 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_0774 22 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 150017902 Common - protein of unknown function UPF0016 Cbei_3062 72 COG2119 COG2119, Predicted membrane protein Function unknown 150019000 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_4188 69 COG1146 COG1146, Ferredoxin Energy production and conversion 150015992 Common - ferric uptake regulator, Fur family Cbei_1108 202 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150017411 Nonpathogen - hypothetical protein Cbei_2553 1 None None None 150016738 Common - hypothetical protein Cbei_1865 1 None None None 150016915 Common - AAA ATPase Cbei_2045 12 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 150015069 Common rpsM 30S ribosomal protein S13 Cbei_0177 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 150018160 Common - ABC transporter related Cbei_3331 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150015255 Common - Glutathionylspermidine synthase-like protein Cbei_0365 14 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 150019045 Common - acylphosphatase Cbei_4233 95 COG1254 AcyP, Acylphosphatases Energy production and conversion 150017024 Common - hypothetical protein Cbei_2155 1 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150019879 Common - HI0933 family protein Cbei_5071 143 COG2081 COG2081, Predicted flavoproteins General function prediction only 150016572 Common - Sporulation stage III, protein AG Cbei_1698 15 None None None 150018887 Common - hypothetical protein Cbei_4075 7 COG5566 COG5566, Uncharacterized conserved protein Function unknown 150018916 Common - ErfK/YbiS/YcfS/YnhG family protein Cbei_4104 16 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150016009 Common - two component transcriptional regulator, winged helix family Cbei_1125 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017912 Common - D-galactose-binding periplasmic protein precursor Cbei_3073 52 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015638 Common - transcriptional antiterminator, BglG Cbei_0752 28 COG3711 BglG, Transcriptional antiterminator Transcription 150016507 Nonpathogen - hypothetical protein Cbei_1631 1 None None None 150017705 Common - hypothetical protein Cbei_2856 9 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 150016446 Common rpmI 50S ribosomal protein L35 Cbei_1570 69 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 150015905 Common argS arginyl-tRNA synthetase Cbei_1019 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150016671 Common - small acid-soluble spore protein Cbei_1798 8 None None None 150018441 Common - NAD(P)H dehydrogenase (quinone) Cbei_3619 46 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150019516 Common - PTS system, glucose subfamily, IIA subunit Cbei_4706 61 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 150017097 Common - Enoyl-CoA hydratase/isomerase Cbei_2230 134 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150015208 Common - Mannose-1-phosphate guanylyltransferase (GDP) Cbei_0318 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 150016279 Common - Integrase, catalytic region Cbei_1398 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 150016692 Common - membrane-spanning protein Cbei_1819 3 COG3689 COG3689, Predicted membrane protein Function unknown 150016632 Common - hypothetical protein Cbei_1758 1 None None None 150017252 Common - transcriptional regulator, GntR family Cbei_2390 136 COG1802 GntR, Transcriptional regulators Transcription 150016855 Common - hypothetical protein Cbei_1983 75 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 150016708 Common - sugar (Glycoside-Pentoside-Hexuronide) transporter Cbei_1835 77 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150019839 Common - sigma-54 factor, interaction domain-containing protein Cbei_5031 156 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 150015733 Common - ubiquitin-associated- domain-containing protein Cbei_0847 6 None None None 150017003 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_2134 249 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 150016000 Common - twitching motility protein Cbei_1116 201 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 150015060 Common rpsE 30S ribosomal protein S5 Cbei_0168 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 150015659 Common - oligoendopeptidase, pepF/M3 family Cbei_0773 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 150015781 Nonpathogen - hypothetical protein Cbei_0895 1 None None None 150016919 Common - ABC transporter related Cbei_2049 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150016103 Common - Phosphotransferase system, phosphocarrier protein HPr Cbei_1219 133 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 150017484 Nonpathogen - hypothetical protein Cbei_2628 4 None None None 150015201 Common - Electron transfer flavoprotein, alpha subunit-like protein Cbei_0311 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150015358 Common - peptidase M22, glycoprotease Cbei_0468 166 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 150019399 Common - phospholipase D/Transphosphatidylase Cbei_4589 158 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 150015416 Common frcK putative fructose transport system kinase Cbei_0526 75 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 150017456 Common - amine oxidase Cbei_2598 30 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 150016495 Common - hypothetical protein Cbei_1619 50 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150019368 Common - PTS system mannose/fructose/sorbose family IID component Cbei_4557 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150016774 Common - hydrogenase large subunit domain protein Cbei_1901 29 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150016310 Common - protein of unknown function DUF161 Cbei_1430 28 COG2364 COG2364, Predicted membrane protein Function unknown 150019263 Common - carbohydrate kinase, FGGY Cbei_4452 62 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 150015645 Common - Serine--pyruvate transaminase Cbei_0759 155 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 150016883 Common - Isopropylmalate/homocitrate/citramalate synthase-like protein Cbei_2011 166 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150016688 Common - putative cell wall binding repeat-containing protein Cbei_1815 12 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018114 Common - hypothetical protein Cbei_3284 6 None None None 150016031 Common - peptidase, membrane zinc metallopeptidase, putative Cbei_1147 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 150016724 Common - cysteine desulfurase, SufS subfamily Cbei_1851 241 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150015402 Common - protein of unknown function UPF0044 Cbei_0512 85 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 150017315 Common - Heptaprenyl diphosphate synthase component I Cbei_2455 16 COG4769 COG4769, Predicted membrane protein Function unknown 150016677 Common - integral membrane sensor signal transduction histidine kinase Cbei_1804 223 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150016371 Common - transcriptional regulator, XRE family Cbei_1492 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 150016713 Common - PTS system, mannose/fructose/sorbose family, IIB subunit Cbei_1840 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150016064 Common rplS 50S ribosomal protein L19 Cbei_1180 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 150017324 Common - Putative GTPase (G3E family)-like protein Cbei_2464 14 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 150018718 Common - regulatory protein, LuxR Cbei_3902 16 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 150017477 Nonpathogen - hypothetical protein Cbei_2621 1 None None None 150018393 Common - RNA polymerase factor sigma-70 Cbei_3569 28 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150019315 Common - periplasmic binding protein Cbei_4504 76 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150016241 Nonpathogen - hypothetical protein Cbei_1359 1 None None None 150015078 Common rplM 50S ribosomal protein L13 Cbei_0186 221 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 150019870 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cbei_5062 227 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 150017471 Nonpathogen - hypothetical protein Cbei_2615 1 None None None 150016786 Common - biotin synthase Cbei_1914 187 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 150019565 Common - glucose-1-phosphate thymidylyltransferase Cbei_4756 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150016525 Common - Phage XkdN-like protein Cbei_1649 2 None None None 150016385 Common - Superoxide dismutase Cbei_1507 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 150017280 Common - putative cell wall binding repeat-containing protein Cbei_2420 4 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019545 Common - glycosyl transferase, group 1 Cbei_4735 187 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150019270 Common - Monosaccharide-transporting ATPase Cbei_4459 121 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 150019113 Common - phage replisome organizer, putative Cbei_4301 4 None None None 150015524 Common - 5'-Nucleotidase domain protein Cbei_0635 141 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150018882 Common - Mn2+/Fe2+ transporter, NRAMP family Cbei_4070 101 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 150017702 Common - major facilitator superfamily MFS_1 Cbei_2853 232 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019168 Common - cysteine synthase A Cbei_4356 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150017393 Common - ferrous iron transport protein B Cbei_2535 196 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 150016821 Nonpathogen - hypothetical protein Cbei_1949 7 None None None 150017675 Common - NERD domain protein Cbei_2824 30 None None None 150018990 Common - transcriptional regulator, XRE family Cbei_4178 111 COG1396 HipB, Predicted transcriptional regulators Transcription 150018576 Common - Cupin 2, conserved barrel domain protein Cbei_3757 29 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150018084 Common - putative transcriptional regulator, Crp/Fnr family Cbei_3253 99 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150017308 Common - positive regulator of sigma E, RseC/MucC Cbei_2448 16 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 150017447 Common - glycosyl transferase, family 2 Cbei_2589 108 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150019444 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_4634 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150019813 Nonpathogen - hypothetical protein Cbei_5005 1 None None None 150018251 Common - transcriptional regulator, LysR family Cbei_3423 188 COG0583 LysR, Transcriptional regulator Transcription 150014958 Common - putative proton-coupled thiamine transporter YuaJ Cbei_0066 13 COG3859 COG3859, Predicted membrane protein Function unknown 150016206 Common - phosphoribosyl-ATP pyrophosphohydrolase Cbei_1324 158 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 150019392 Common - ABC transporter related Cbei_4582 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150019687 Common - putative ribonuclease BN Cbei_4879 132 COG1295 Rbn, Predicted membrane protein Function unknown 150019424 Nonpathogen - Coat F domain protein Cbei_4614 2 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 150018324 Common - binding-protein-dependent transport systems inner membrane component Cbei_3499 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150015885 Common - beta-lactamase, putative Cbei_0999 42 COG2367 PenP, Beta-lactamase class A Defense mechanisms 150018223 Common - hypothetical protein Cbei_3395 74 COG5412 COG5412, Phage-related protein Function unknown 150019841 Common - nitrogen regulatory protein P-II Cbei_5033 185 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150019848 Common - pyridoxine biosynthesis protein Cbei_5040 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 150018032 Common - hypothetical protein Cbei_3200 60 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150017093 Common - protein of unknown function DUF6, transmembrane Cbei_2226 94 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 150017111 Common - Cupin 2, conserved barrel domain protein Cbei_2246 37 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 150018500 Nonpathogen - hypothetical protein Cbei_3680 1 None None None 150017247 Common - ROK family protein Cbei_2385 144 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150016941 Common - hypothetical protein Cbei_2071 1 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150015725 Common - GatB/Yqey domain protein Cbei_0839 154 COG1610 COG1610, Uncharacterized conserved protein Function unknown 150016159 Common - adenine deaminase Cbei_1277 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 150018240 Nonpathogen - hypothetical protein Cbei_3412 2 None None None 150019559 Common - ABC transporter related Cbei_4750 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150017710 Common - transposase Cbei_2861 6 None None None 150014951 Common ksgA dimethyladenosine transferase Cbei_0059 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 150017223 Common - regulatory protein, ArsR Cbei_2361 13 COG4189 COG4189, Predicted transcriptional regulator Transcription 150016106 Common - hypothetical protein Cbei_1222 8 None None None 150019676 Common - cell division ATP-binding protein FtsE Cbei_4868 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 150019725 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Cbei_4917 97 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 150016762 Common - pseudouridine synthase Cbei_1889 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150015243 Common - extracellular solute-binding protein, family 5 Cbei_0353 51 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 150019185 Common - hypothetical protein Cbei_4373 2 None None None 150016703 Common - putative oxidoreductase Cbei_1830 189 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150016619 Common - protein of unknown function DUF606 Cbei_1745 3 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 150019090 Common - N-acylneuraminate-9-phosphate synthase Cbei_4278 79 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 150019200 Common - putative cell wall binding repeat-containing protein Cbei_4389 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017148 Nonpathogen - hypothetical protein Cbei_2285 1 None None None 150019175 Nonpathogen - hypothetical protein Cbei_4363 1 None None None 150016793 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Cbei_1921 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150019858 Common hppA membrane-bound proton-translocating pyrophosphatase Cbei_5050 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 150016550 Common - putative cell wall binding repeat-containing protein Cbei_1675 2 None None None 150019892 Common rpsR 30S ribosomal protein S18 Cbei_5084 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 150016296 Common - Rubrerythrin Cbei_1416 24 COG1592 COG1592, Rubrerythrin Energy production and conversion 150016710 Common - PfkB domain protein Cbei_1837 154 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150019773 Common - methyl-accepting chemotaxis sensory transducer Cbei_4965 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015154 Common - protein of unknown function DUF214 Cbei_0263 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150017497 Common - phage integrase family protein Cbei_2641 176 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150019847 Common - SNO glutamine amidotransferase Cbei_5039 94 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 150014918 Common - methylglyoxal synthase Cbei_0026 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 150018477 Nonpathogen - iron-sulfur flavoprotein Cbei_3656 3 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150014943 Common - nucleoside recognition domain protein Cbei_0051 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 150017691 Common - SCP-like extracellular protein Cbei_2841 78 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150018557 Common - YibE/F family protein Cbei_3738 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150016333 Common - YodP Cbei_1453 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150017894 Common - FMN-binding domain protein Cbei_3054 95 COG0348 NapH, Polyferredoxin Energy production and conversion 150018682 Common - transcriptional regulator, LysR family Cbei_3865 192 COG0583 LysR, Transcriptional regulator Transcription 150016078 Common - protein of unknown function UPF0118 Cbei_1194 129 COG0628 PerM, Predicted permease General function prediction only 150019580 Common - protein of unknown function DUF161 Cbei_4771 67 COG1284 COG1284, Uncharacterized conserved protein Function unknown 150015908 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Cbei_1022 35 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 150018976 Nonpathogen - hypothetical protein Cbei_4164 1 COG3874 COG3874, Uncharacterized conserved protein Function unknown 150016767 Nonpathogen - hypothetical protein Cbei_1894 11 None None None 150014962 Common - aconitate hydratase Cbei_0070 223 COG1048 AcnA, Aconitase A Energy production and conversion 150018760 Common - nitroreductase Cbei_3948 71 COG0778 NfnB, Nitroreductase Energy production and conversion 150018458 Common - MATE efflux family protein Cbei_3636 107 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150017160 Nonpathogen - hypothetical protein Cbei_2298 1 None None None 150015148 Common - 4'-phosphopantetheinyl transferase Cbei_0256 57 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 150016355 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_1475 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150018669 Common - ABC transporter related Cbei_3852 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150016530 Common - hypothetical protein Cbei_1654 2 None None None 150018330 Common - hypothetical protein Cbei_3505 9 None None None 150018771 Common - transcriptional regulator, XRE family Cbei_3959 30 COG1476 COG1476, Predicted transcriptional regulators Transcription 150016174 Common - hypothetical protein Cbei_1292 1 None None None 150017430 Common - aldehyde dehydrogenase Cbei_2572 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150018607 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3788 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150019321 Common - glycerol-3-phosphate responsive antiterminator Cbei_4510 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 150015176 Common - helix-turn-helix- domain containing protein, AraC type Cbei_0286 134 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015236 Common - nitroreductase Cbei_0346 105 COG0778 NfnB, Nitroreductase Energy production and conversion 150018936 Common - methyl-accepting chemotaxis sensory transducer Cbei_4124 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017738 Common - extracellular solute-binding protein, family 3 Cbei_2890 132 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150015000 Common - hypothetical protein Cbei_0108 1 None None None 150018022 Common - hypothetical protein Cbei_3190 2 None None None 150017773 Common - acriflavin resistance protein Cbei_2928 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150014968 Common asnC asparaginyl-tRNA synthetase Cbei_0076 217 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150016183 Common - membrane associated protein Cbei_1301 12 None None None 150017437 Common - dTDP-4-dehydrorhamnose reductase Cbei_2579 181 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 150017856 Common - flavodoxin Cbei_3015 38 COG0716 FldA, Flavodoxins Energy production and conversion 150019333 Common - Excinuclease ABC, C subunit domain protein Cbei_4522 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 150018541 Nonpathogen - hypothetical protein Cbei_3722 1 None None None 150019406 Common - hypothetical protein Cbei_4596 1 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 150019491 Common - L-fucose isomerase related protein Cbei_4681 13 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 150017181 Common - transcriptional regulator, GntR family Cbei_2319 113 COG2188 PhnF, Transcriptional regulators Transcription 150019220 Common - Saccharopine dehydrogenase Cbei_4409 60 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 150019245 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_4434 99 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019600 Common - methyl-accepting chemotaxis sensory transducer Cbei_4791 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019739 Common - binding-protein-dependent transport systems inner membrane component Cbei_4931 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150017037 Nonpathogen - hypothetical protein Cbei_2168 1 None None None 150016814 Common - dihydropyrimidinase Cbei_1942 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150015365 Common - metallophosphoesterase Cbei_0475 74 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 150019065 Common flhA flagellar biosynthesis protein A Cbei_4253 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 150015919 Common - GerA spore germination protein Cbei_1033 15 None None None 150015869 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Cbei_0983 228 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150015707 Common rpsT 30S ribosomal protein S20 Cbei_0821 19 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 150015432 Common - PTS system, galactitol-specific IIB component, putative Cbei_0542 11 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 150016480 Common - putative pilus biogenesis protein Cbei_1604 149 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 150018054 Nonpathogen - hypothetical protein Cbei_3222 1 None None None 150019832 Common - alpha/beta superfamily hydrolase Cbei_5024 34 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 150018959 Common - basic membrane lipoprotein Cbei_4147 84 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 150017634 Common - MATE efflux family protein Cbei_2781 181 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150016136 Common - transcriptional regulator, TetR family Cbei_1253 70 COG1309 AcrR, Transcriptional regulator Transcription 150015292 Common - thymidine kinase Cbei_0402 97 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 150016573 Common - stage III sporulation protein AH Cbei_1699 9 None None None 150018309 Common - transcriptional regulator, XRE family Cbei_3483 58 COG1476 COG1476, Predicted transcriptional regulators Transcription 150019373 Common - glucosamine-6-phosphate isomerase Cbei_4562 83 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 150018319 Common - hypothetical protein Cbei_3494 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 150018101 Nonpathogen - hypothetical protein Cbei_3270 1 None None None 150015777 Nonpathogen - hypothetical protein Cbei_0891 1 None None None 150017179 Common - cobalamin (vitamin B12) biosynthesis CbiG protein Cbei_2317 86 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 150016864 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Cbei_1992 159 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 150018512 Common - ABC transporter related Cbei_3693 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150018427 Nonpathogen - hypothetical protein Cbei_3605 1 None None None 150016894 Common - protein of unknown function DUF542, ScdA domain protein Cbei_2022 46 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 150019199 Nonpathogen - hypothetical protein Cbei_4388 1 None None None 150019440 Common - glycosyl transferase, family 2 Cbei_4630 146 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150015740 Common - protein of unknown function DUF633 Cbei_0854 29 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 150017986 Common - UvrD/REP helicase Cbei_3151 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150016605 Common - two component transcriptional regulator, winged helix family Cbei_1731 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017491 Common - hypothetical protein Cbei_2635 9 COG3500 COG3500, Phage protein D General function prediction only 150017832 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_2991 197 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 150017907 Nonpathogen - hypothetical protein Cbei_3067 1 None None None 150015851 Common - phosphotransferase system PTS, sorbose-specific IIC subunit Cbei_0965 40 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150015964 Common - HutP Cbei_1078 10 None None None 150017165 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_2303 4 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150017685 Common - transcriptional regulator, TetR family Cbei_2835 36 COG1309 AcrR, Transcriptional regulator Transcription 150018029 Common - glycosyltransferase, MGT family Cbei_3197 38 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 150018848 Common - 6-phospho-beta-glucosidase Cbei_4036 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150015310 Common - hypothetical protein Cbei_0420 1 None None None 150018316 Common - protein of unknown function DUF692 Cbei_3491 11 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 150017538 Common - alpha/beta superfamily hydrolase Cbei_2683 9 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 150019572 Common - putative cell wall binding repeat-containing protein Cbei_4763 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019703 Common - putative glucokinase, ROK family Cbei_4895 171 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150018945 Common - beta-lactamase domain protein Cbei_4133 158 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 150017683 Common - PTS system, beta-glucoside-specific IIABC subunit Cbei_2833 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150016306 Common - protein of unknown function DUF1121 Cbei_1426 21 None None None 150017382 Common - Cof-like hydrolase Cbei_2524 111 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150019617 Common - diguanylate cyclase and metal dependent phosphohydrolase Cbei_4808 184 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150015396 Common - hypothetical protein Cbei_0506 42 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 150016631 Common - hypothetical protein Cbei_1757 1 None None None 150017156 Nonpathogen - hypothetical protein Cbei_2294 1 None None None 150019756 Common - hypothetical protein Cbei_4948 2 None None None 150019351 Common - adenylate cyclase Cbei_4540 2 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 150019356 Common - sugar transporter Cbei_4545 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018486 Nonpathogen - hypothetical protein Cbei_3666 2 None None None 150016324 Common - alpha amylase, catalytic region Cbei_1444 157 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150017657 Nonpathogen - hypothetical protein Cbei_2805 2 None None None 150019279 Common - transcriptional regulator, GntR family Cbei_4468 110 COG2188 PhnF, Transcriptional regulators Transcription 150015325 Common - two component transcriptional regulator, winged helix family Cbei_0435 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150018119 Common - polysaccharide deacetylase Cbei_3290 82 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150019590 Common - extracellular solute-binding protein, family 3 Cbei_4781 182 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150019345 Common - transcriptional antiterminator, BglG Cbei_4534 30 COG3711 BglG, Transcriptional antiterminator Transcription 150016022 Common - hypothetical protein Cbei_1138 2 None None None 150016563 Nonpathogen - hypothetical protein Cbei_1689 1 None None None 150018066 Common - transposase IS116/IS110/IS902 family protein Cbei_3235 32 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150019599 Nonpathogen - hypothetical protein Cbei_4790 1 COG3595 COG3595, Uncharacterized conserved protein Function unknown 150018569 Common - protein of unknown function DUF1706 Cbei_3750 22 COG4283 COG4283, Uncharacterized conserved protein Function unknown 150016510 Common - hypothetical protein Cbei_1634 11 None None None 150018046 Common - hypothetical protein Cbei_3214 5 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150016425 Common - protein of unknown function DUF554 Cbei_1549 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 150017030 Nonpathogen - hypothetical protein Cbei_2161 1 None None None 150015229 Common - PTS system, glucitol/sorbitol-specific IIA subunit Cbei_0339 21 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 150015876 Common - Formiminotransferase-cyclodeaminase Cbei_0990 37 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 150016262 Common - response regulator receiver protein Cbei_1381 210 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150017594 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cbei_2741 42 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 150018093 Common - Protein of unknown function DUF1980 Cbei_3262 18 COG3689 COG3689, Predicted membrane protein Function unknown 150018808 Common - signal peptidase I Cbei_3996 192 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150015182 Common - hypothetical protein Cbei_0292 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150016238 Nonpathogen - hypothetical protein Cbei_1356 1 None None None 150018285 Common - acetyltransferase (the isoleucine patch superfamily) Cbei_3458 158 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150015347 Common - transcriptional regulator, DeoR family Cbei_0457 45 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150019468 Common - Mannitol dehydrogenase, C-terminal domain Cbei_4658 76 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150016430 Common - conserved protein (pathogens) Cbei_1554 7 None None None 150017424 Common - hypothetical protein Cbei_2566 33 None None None 150018856 Common - Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Cbei_4044 73 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150017288 Common - peptidase T Cbei_2428 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 150018417 Common - transcriptional regulator, PadR-like family Cbei_3595 6 COG1695 COG1695, Predicted transcriptional regulators Transcription 150017888 Common - Xylan 1,4-beta-xylosidase Cbei_3047 76 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 150015841 Common - PTS system fructose subfamily IIA component Cbei_0955 50 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150017274 Common uvsE putative UV damage endonuclease Cbei_2414 24 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 150017569 Nonpathogen - hypothetical protein Cbei_2716 1 None None None 150015575 Common - 4'-phosphopantetheinyl transferase Cbei_0687 7 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 150018127 Common - putative galactoside ABC transporter Cbei_3298 61 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015989 Common - hypothetical protein Cbei_1105 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 150015986 Common - PRC-barrel domain protein Cbei_1102 1 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 150016470 Common - MotA/TolQ/ExbB proton channel Cbei_1594 112 COG1291 MotA, Flagellar motor component Cell motility and secretion 150018573 Nonpathogen - S-adenosylmethionine-dependent methyltransferase Cbei_3754 1 None None None 150015973 Common - membrane bound O-acyl transferase, MBOAT family protein Cbei_1088 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 150016165 Common hemA glutamyl-tRNA reductase Cbei_1283 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 150017981 Common - transcriptional regulator, TetR family Cbei_3144 79 COG1309 AcrR, Transcriptional regulator Transcription 150015826 Common - flavin reductase domain protein, FMN-binding Cbei_0940 90 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150015251 Common - multi-sensor signal transduction histidine kinase Cbei_0361 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017195 Common - RelA/SpoT domain protein Cbei_2333 91 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 150015220 Nonpathogen - Type II secretory pathway pseudopilin PulG-like protein Cbei_0330 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150018274 Common - solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta Cbei_3447 16 COG3382 COG3382, Uncharacterized conserved protein Function unknown 150017528 Nonpathogen - hypothetical protein Cbei_2673 1 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 150016334 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_1454 7 None None None 150015034 Common rplJ 50S ribosomal protein L10 Cbei_0142 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 150014949 Common - 3D domain protein Cbei_0057 38 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 150019717 Common - 1,4-alpha-glucan branching enzyme Cbei_4909 151 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 150019904 Common - parB-like partition protein Cbei_5096 183 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150015170 Nonpathogen - hypothetical protein Cbei_0280 1 None None None 150015094 Common - HI0933 family protein Cbei_0202 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 150016537 Nonpathogen - hypothetical protein Cbei_1661 1 None None None 150017056 Nonpathogen - hypothetical protein Cbei_2187 2 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150015925 Common - binding-protein-dependent transport systems inner membrane component Cbei_1039 89 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150018134 Common - hypothetical protein Cbei_3305 43 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 150018148 Nonpathogen - hypothetical protein Cbei_3319 1 None None None 150015137 Common - Mannitol dehydrogenase, C-terminal domain Cbei_0245 86 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150019550 Common - Protein-tyrosine-phosphatase Cbei_4740 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150015295 Common - hypothetical protein Cbei_0405 1 None None None 150018099 Nonpathogen - Holin, phage phi LC3 Cbei_3268 1 COG5546 COG5546, Small integral membrane protein Function unknown 150019536 Common - putative cell wall binding repeat-containing protein Cbei_4726 8 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015382 Common - rod shape-determining protein MreC Cbei_0492 148 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 150018600 Common - ferredoxin Cbei_3781 228 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150019764 Common - CrcB protein Cbei_4956 189 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 150019652 Common - oxidoreductase domain protein Cbei_4843 182 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150018858 Common - ethanolamine utilization protein EutJ family protein Cbei_4046 214 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 150019363 Common - iron-containing alcohol dehydrogenase Cbei_4552 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150018566 Nonpathogen - hypothetical protein Cbei_3747 1 None None None 150015047 Common rpsS 30S ribosomal protein S19 Cbei_0155 240 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 150016114 Common - binding-protein-dependent transport systems inner membrane component Cbei_1230 161 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150018419 Common - flavin reductase domain protein, FMN-binding Cbei_3597 57 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150015898 Common - Rubredoxin-type Fe(Cys)4 protein Cbei_1012 114 COG1773 COG1773, Rubredoxin Energy production and conversion 150016287 Common - hypothetical protein Cbei_1407 1 None None None 150019603 Common - aspartate aminotransferase Cbei_4794 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150018126 Common - hypothetical protein Cbei_3297 3 None None None 150019864 Common - acyl-CoA dehydrogenase domain protein Cbei_5056 203 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150015221 Common - inositol-5-monophosphate dehydrogenase Cbei_0331 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 150017596 Common - GCN5-related N-acetyltransferase Cbei_2743 7 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150015972 Common - diguanylate cyclase Cbei_1087 181 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150018064 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_3233 31 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150018149 Common - methyl-accepting chemotaxis sensory transducer Cbei_3320 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015380 Common radC DNA repair protein RadC Cbei_0490 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 150016074 Common pyrH uridylate kinase Cbei_1190 238 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 150016422 Common hisS histidyl-tRNA synthetase Cbei_1544 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150019863 Common - beta-lactamase domain protein Cbei_5055 87 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150015666 Common - cyclic nucleotide-binding protein Cbei_0780 81 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150017851 Common - conserved hypothetical protein, CF-29 family Cbei_3010 1 None None None 150018454 Nonpathogen - hypothetical protein Cbei_3632 1 None None None 150015250 Common - hypothetical protein Cbei_0360 6 None None None 150016356 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_1476 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150019453 Common - glycoside hydrolase, family 1 Cbei_4643 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150018567 Nonpathogen - hypothetical protein Cbei_3748 2 None None None 150019836 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Cbei_5028 205 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150016327 Common - small acid-soluble spore protein, alpha/beta type Cbei_1447 15 None None None 150019893 Common - single-strand binding protein Cbei_5085 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150014930 Common - hypothetical protein Cbei_0038 20 COG3949 COG3949, Uncharacterized membrane protein Function unknown 150019354 Common - coenzyme A transferase Cbei_4543 104 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 150015186 Common - hypothetical protein Cbei_0296 2 None None None 150015630 Common - diguanylate cyclase with PAS/PAC sensor Cbei_0744 188 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150018505 Common - hypothetical protein Cbei_3685 7 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150019584 Common - phage replisome organizer, putative Cbei_4775 4 None None None 150019752 Common - hypothetical protein Cbei_4944 1 None None None 150019262 Nonpathogen - hypothetical protein Cbei_4451 1 None None None 150016435 Common - uridine kinase Cbei_1559 85 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 150018273 Common - Radical SAM domain protein Cbei_3446 45 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 150019807 Nonpathogen - hypothetical protein Cbei_4999 1 None None None 150016994 Common - GCN5-related N-acetyltransferase Cbei_2125 3 None None None 150016427 Common - Homoserine dehydrogenase Cbei_1551 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 150017586 Common - hypothetical protein Cbei_2733 1 None None None 150015981 Common - transcriptional regulator, BadM/Rrf2 family Cbei_1097 178 COG1959 COG1959, Predicted transcriptional regulator Transcription 150015385 Common - sugar fermentation stimulation protein A Cbei_0495 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 150016477 Common - hypothetical protein Cbei_1601 2 None None None 150017929 Common - hypothetical protein Cbei_3090 14 None None None 150018767 Nonpathogen - hypothetical protein Cbei_3955 1 None None None 150018846 Common - protein of unknown function DUF939 Cbei_4034 9 COG4129 COG4129, Predicted membrane protein Function unknown 150014975 Common - two component transcriptional regulator, winged helix family Cbei_0083 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015353 Common - hemerythrin-like metal-binding protein Cbei_0463 50 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150014942 Common - hypothetical protein Cbei_0050 1 None None None 150015580 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Cbei_0692 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150015573 Common - Alcohol dehydrogenase GroES domain protein Cbei_0685 160 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150016387 Nonpathogen - protein of unknown function DUF434 Cbei_1509 16 COG2454 COG2454, Uncharacterized conserved protein Function unknown 150017672 Nonpathogen - hypothetical protein Cbei_2821 1 None None None 150018941 Common - Transcriptional regulator IclR-like protein Cbei_4129 122 COG1414 IclR, Transcriptional regulator Transcription 150018425 Common - protein of unknown function DUF421 Cbei_3603 48 COG2323 COG2323, Predicted membrane protein Function unknown 150019191 Nonpathogen - hypothetical protein Cbei_4380 2 COG4253 COG4253, Uncharacterized protein conserved in bacteria Function unknown 150019575 Common - putative cell wall binding repeat-containing protein Cbei_4766 18 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018151 Common - two component transcriptional regulator, winged helix family Cbei_3322 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017508 Common - 3-oxoacid CoA-transferase, B subunit Cbei_2653 109 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 150017398 Common folE GTP cyclohydrolase I Cbei_2540 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 150018313 Common - hypothetical protein Cbei_3488 24 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150018471 Common - transcriptional regulator, TetR family Cbei_3650 132 COG1309 AcrR, Transcriptional regulator Transcription 150017153 Nonpathogen - hypothetical protein Cbei_2291 1 None None None 150018045 Common - metal dependent phosphohydrolase Cbei_3213 62 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150017660 Common - hypothetical protein Cbei_2808 38 None None None 150018135 Common - hypothetical protein Cbei_3306 6 None None None 150016117 Common - 2-dehydropantoate 2-reductase Cbei_1233 116 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 150015886 Common pyrB aspartate carbamoyltransferase catalytic subunit Cbei_1000 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 150018225 Common - phage-like element pbsx protein XkdM Cbei_3397 6 None None None 150018814 Common - Endopeptidase Clp Cbei_4002 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150019194 Common - beta-lactamase domain protein Cbei_4383 21 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 150015378 Common - hypothetical protein Cbei_0488 1 None None None 150017840 Common - UbiA prenyltransferase Cbei_2999 113 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 150015230 Common - sorbitol-6-phosphate 2-dehydrogenase Cbei_0340 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150018483 Common - two component transcriptional regulator, winged helix family Cbei_3663 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016163 Common - protein of unknown function DUF1294 Cbei_1281 10 COG3326 COG3326, Predicted membrane protein Function unknown 150018061 Common - ThiJ/PfpI domain protein Cbei_3229 121 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150016186 Common - hypothetical protein Cbei_1304 1 None None None 150018302 Common - Ketopantoate reductase ApbA/PanE, N-terminal domain protein Cbei_3475 4 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 150016179 Nonpathogen - hypothetical protein Cbei_1297 1 None None None 150019349 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_4538 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150016487 Common - Ion transport 2 domain protein Cbei_1611 6 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150017353 Common - hypothetical protein Cbei_2495 23 COG3875 COG3875, Uncharacterized conserved protein Function unknown 150019708 Common - hypothetical protein Cbei_4900 1 None None None 150016822 Common - hypothetical protein Cbei_1950 5 None None None 150016637 Common - inner-membrane translocator Cbei_1763 162 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 150015374 Common rpsA 30S ribosomal protein S1 Cbei_0484 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 150018253 Nonpathogen - hypothetical protein Cbei_3425 1 None None None 150019409 Common - hypothetical protein Cbei_4599 16 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 150018868 Common - microcompartments protein Cbei_4056 16 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150018518 Common - beta-lactamase Cbei_3699 153 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150016609 Nonpathogen - hypothetical protein Cbei_1735 1 None None None 150016085 Common - hypothetical protein Cbei_1201 5 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 150015141 Common - hypothetical protein Cbei_0249 26 None None None 150017725 Common - transcriptional regulator, TetR family Cbei_2877 12 COG1309 AcrR, Transcriptional regulator Transcription 150016800 Common - hypothetical protein Cbei_1928 7 None None None 150015920 Common - asparagine synthase (glutamine-hydrolyzing) Cbei_1034 153 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 150016045 Common - hypothetical protein Cbei_1161 32 None None None 150016777 Common - transcriptional regulator, CarD family Cbei_1904 55 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 150018703 Common - protein of unknown function DUF1349 Cbei_3887 26 COG3506 COG3506, Uncharacterized conserved protein Function unknown 150018829 Common - methyl-accepting chemotaxis sensory transducer Cbei_4017 166 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018859 Common - Propanediol utilization protein Cbei_4047 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 150018621 Nonpathogen - hypothetical protein Cbei_3802 1 None None None 150016379 Common - Glycosyl transferase Cbei_1501 15 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 150018967 Common - Threonine aldolase Cbei_4155 69 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 150016331 Common - Rhodanese domain protein Cbei_1451 74 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150016447 Common rplT 50S ribosomal protein L20 Cbei_1571 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 150016125 Common - hypothetical protein Cbei_1241 29 COG3875 COG3875, Uncharacterized conserved protein Function unknown 150017730 Common - protein of unknown function DUF1121 Cbei_2882 22 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 150019404 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cbei_4594 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150014993 Common - Formate--tetrahydrofolate ligase Cbei_0101 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 150015072 Common - DNA-directed RNA polymerase subunit alpha Cbei_0180 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 150018098 Common - glycoside hydrolase, family 25 Cbei_3267 41 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150017741 Common - binding-protein-dependent transport systems inner membrane component Cbei_2893 182 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150015133 Common - transcriptional regulator, MarR family Cbei_0241 36 COG1846 MarR, Transcriptional regulators Transcription 150019214 Nonpathogen - hypothetical protein Cbei_4403 1 None None None 150018338 Common - regulatory protein, ArsR Cbei_3513 29 COG0640 ArsR, Predicted transcriptional regulators Transcription 150019258 Common - DegV family protein Cbei_4447 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150019884 Common - hypothetical protein Cbei_5076 1 None None None 150017958 Common - deoxyribose-phosphate aldolase Cbei_3120 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 150015239 Common - nitrogen-fixing NifU domain protein Cbei_0349 100 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 150016933 Common - phosphoenolpyruvate synthase Cbei_2063 160 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150016251 Nonpathogen - hypothetical protein Cbei_1369 1 None None None 150018377 Common - uncharacterized protein, YcgL-like protein Cbei_3553 11 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 150016370 Common - phage integrase family protein Cbei_1491 87 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150016338 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Cbei_1458 120 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150018939 Common - Dihydroxy-acid dehydratase Cbei_4127 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150017079 Common - transcriptional regulator, HxlR family Cbei_2210 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 150015366 Common - hypothetical protein Cbei_0476 48 COG4717 COG4717, Uncharacterized conserved protein Function unknown 150019273 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_4462 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019464 Common - putative lysophospholipase Cbei_4654 64 COG2267 PldB, Lysophospholipase Lipid metabolism 150016225 Common - protein of unknown function DUF1508 Cbei_1343 28 COG3422 COG3422, Uncharacterized conserved protein Function unknown 150016873 Common - nitrogen regulatory protein P-II Cbei_2001 102 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 150017893 Common - two component transcriptional regulator, winged helix family Cbei_3053 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015589 Nonpathogen - hypothetical protein Cbei_0703 1 None None None 150016711 Common - altronate oxidoreductase Cbei_1838 87 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150016756 Common - amino acid permease-associated region Cbei_1883 46 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150015929 Common - branched-chain amino acid aminotransferase Cbei_1043 202 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150019908 Common - single-stranded nucleic acid binding R3H domain protein Cbei_5100 69 COG1847 Jag, Predicted RNA-binding protein General function prediction only 150019711 Common - L-lactate dehydrogenase Cbei_4903 168 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 150019317 Common - protein of unknown function DUF1667 Cbei_4506 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 150019360 Common - Myo-inositol catabolism IolB domain protein Cbei_4549 45 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 150019087 Nonpathogen - hypothetical protein Cbei_4275 1 None None None 150016612 Nonpathogen - hypothetical protein Cbei_1738 1 None None None 150016576 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Cbei_1702 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 150015637 Common - PTS system, glucose subfamily, IIA subunit Cbei_0751 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150018852 Common - peptidase M29, aminopeptidase II Cbei_4040 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 150017108 Common - transcriptional regulator, HxlR family Cbei_2242 152 COG1733 COG1733, Predicted transcriptional regulators Transcription 150016246 Nonpathogen - hypothetical protein Cbei_1364 1 None None None 150016718 Common - hypothetical protein Cbei_1845 2 None None None 150019079 Common fliG flagellar motor switch protein G Cbei_4267 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 150015013 Common - UvrB/UvrC protein Cbei_0121 22 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 150018207 Common - YbaK/prolyl-tRNA synthetase associated region Cbei_3379 37 COG3760 COG3760, Uncharacterized conserved protein Function unknown 150015129 Common - ABC transporter related Cbei_0237 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150018688 Common - PTS system, mannose/fructose/sorbose family, IIC subunit Cbei_3872 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150019324 Common - protein of unknown function DUF421 Cbei_4513 52 COG2323 COG2323, Predicted membrane protein Function unknown 150018021 Nonpathogen - hypothetical protein Cbei_3189 2 None None None 150019416 Common - metallophosphoesterase Cbei_4606 17 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 150019017 Common - response regulator receiver and ANTAR domain protein Cbei_4205 90 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 150016674 Common - protein of unknown function DUF218 Cbei_1801 51 COG1434 COG1434, Uncharacterized conserved protein Function unknown 150015716 Common - chaperone protein DnaK Cbei_0830 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 150016642 Common - hypothetical protein Cbei_1768 3 None None None 150014959 Common - degV family protein Cbei_0067 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 150015266 Common - endodeoxyribonuclease RusA Cbei_0376 2 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 150016292 Common - Pyruvate kinase Cbei_1412 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 150015726 Common - protein of unknown function DUF1429 Cbei_0840 15 None None None 150016158 Common - metal dependent phosphohydrolase Cbei_1276 120 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150017765 Common - integral membrane sensor signal transduction histidine kinase Cbei_2920 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016506 Nonpathogen - hypothetical protein Cbei_1630 2 None None None 150019095 Common - hypothetical protein Cbei_4283 1 None None None 150019789 Common - transcriptional regulator, MarR family Cbei_4981 50 COG1846 MarR, Transcriptional regulators Transcription 150018803 Nonpathogen - hypothetical protein Cbei_3991 2 None None None 150019004 Common - sulfate ABC transporter, inner membrane subunit CysT Cbei_4192 227 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 150018497 Nonpathogen - hypothetical protein Cbei_3677 5 None None None 150016006 Common - Sporulation protein YlmC/YmxH Cbei_1122 14 COG1873 COG1873, Uncharacterized conserved protein Function unknown 150015902 Common - hypothetical protein Cbei_1016 27 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150016535 Common - hypothetical protein Cbei_1659 1 None None None 150016395 Common - uncharacterized membrane protein, putative Cbei_1517 10 None None None 150019779 Common - transcriptional regulator, HxlR family Cbei_4971 149 COG1733 COG1733, Predicted transcriptional regulators Transcription 150015285 Common - Sporulation stage II, protein R Cbei_0395 15 None None None 150015748 Common - putative transcriptional regulator, PucR family Cbei_0862 23 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 150016205 Common - Phosphoribosyl-AMP cyclohydrolase Cbei_1323 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 150017709 Common - helix-turn-helix- domain containing protein, AraC type Cbei_2860 100 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150018140 Common - short-chain dehydrogenase/reductase SDR Cbei_3311 210 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150017294 Common - NLP/P60 protein Cbei_2434 164 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150014948 Common - hydrolase, TatD family Cbei_0056 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 150015965 Common - protein of unknown function DUF534 Cbei_1079 55 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 150015691 Common - phage infection protein, putative Cbei_0805 39 COG1511 COG1511, Predicted membrane protein Function unknown 150018885 Common - regulatory protein, LuxR Cbei_4073 18 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 150019445 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_4635 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150018030 Common - prophage antirepressor Cbei_3198 36 COG3617 COG3617, Prophage antirepressor Transcription 150017145 Common - aldehyde dehydrogenase Cbei_2282 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150015521 Common - Nitrogenase Cbei_0632 62 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150017166 Common - cell wall hydrolase/autolysin Cbei_2304 19 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150018593 Common - integral membrane sensor signal transduction histidine kinase Cbei_3774 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019780 Common - Alpha-N-arabinofuranosidase Cbei_4972 41 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 150016655 Common valS valyl-tRNA synthetase Cbei_1782 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017563 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_2709 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150017281 Common - iron-containing alcohol dehydrogenase Cbei_2421 173 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 150016042 Common - ATP-dependent DNA helicase RecG Cbei_1158 241 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 150017220 Common - binding-protein-dependent transport systems inner membrane component Cbei_2358 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150018574 Nonpathogen - hypothetical protein Cbei_3755 4 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150015079 Common rpsI 30S ribosomal protein S9 Cbei_0187 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 150018948 Common - alpha amylase, catalytic region Cbei_4136 174 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150014913 Common - ABC transporter related Cbei_0021 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150019844 Common - sulfate transporter Cbei_5036 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 150018015 Common - putative transcriptional regulator, MerR family Cbei_3183 112 COG0789 SoxR, Predicted transcriptional regulators Transcription 150015678 Common - quinolinate synthetase Cbei_0792 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 150019685 Common - hypothetical protein Cbei_4877 1 None None None 150017674 Common - DNA-3-methyladenine glycosylase I Cbei_2823 133 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 150016307 Common - glutamyl-tRNA synthetase Cbei_1427 244 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150017551 Common - hypothetical protein Cbei_2697 12 COG0645 COG0645, Predicted kinase General function prediction only 150017214 Common - hypothetical protein Cbei_2352 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 150016243 Nonpathogen - hypothetical protein Cbei_1361 1 None None None 150014961 Common aksA trans-homoaconitate synthase Cbei_0069 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150018679 Common - pyruvate phosphate dikinase, PEP/pyruvate-binding Cbei_3862 172 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150019894 Common rpsF 30S ribosomal protein S6 Cbei_5086 207 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 150017189 Common - hypothetical protein Cbei_2327 16 None None None 150015510 Common - Nitrogenase Cbei_0621 61 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150017383 Common - 3D domain protein Cbei_2525 6 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150019732 Common - major facilitator superfamily MFS_1 Cbei_4924 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150017658 Common - hypothetical protein Cbei_2806 8 None None None 150019857 Common - hypothetical protein Cbei_5049 1 None None None 150018331 Common - transcriptional regulator, LysR family Cbei_3506 186 COG0583 LysR, Transcriptional regulator Transcription 150019492 Common - methyl-accepting chemotaxis sensory transducer Cbei_4682 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016411 Common tgt queuine tRNA-ribosyltransferase Cbei_1533 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 150016842 Common - dihydropyrimidinase Cbei_1970 205 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150016490 Common - hypothetical protein Cbei_1614 6 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 150016782 Common - FAD dependent oxidoreductase Cbei_1910 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 150017117 Common - two component transcriptional regulator, winged helix family Cbei_2252 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150019046 Common - putative hydrolase Cbei_4234 76 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 150017941 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3102 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150017631 Common - nitroreductase Cbei_2778 77 COG0778 NfnB, Nitroreductase Energy production and conversion 150015423 Nonpathogen - recombinase Cbei_0533 1 None None None 150017948 Common - multimeric flavodoxin WrbA fused to cytochrome c-like domain Cbei_3109 26 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150018250 Common - putative galactoside ABC transporter Cbei_3422 69 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019504 Common - Nucleotidyl transferase Cbei_4694 139 COG4750 LicC, CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes Cell envelope biogenesis, outer membrane 150016683 Common - hypothetical protein Cbei_1810 11 COG1971 COG1971, Predicted membrane protein Function unknown 150015441 Common - apurinic endonuclease Apn1 Cbei_0552 102 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 150016036 Common - ribosome-associated GTPase Cbei_1152 163 COG1162 COG1162, Predicted GTPases General function prediction only 150016239 Common - hypothetical protein Cbei_1357 5 None None None 150018551 Common - AAA ATPase Cbei_3732 16 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150016403 Common - protein of unknown function DUF1130 Cbei_1525 35 COG5483 COG5483, Uncharacterized conserved protein Function unknown 150018076 Common - Peptidoglycan-binding domain 1 protein Cbei_3245 3 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 150017149 Common - ErfK/YbiS/YcfS/YnhG family protein Cbei_2287 77 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150016770 Common - Mg2+ transporter protein, CorA family protein Cbei_1897 145 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 150016197 Common - Histidine--tRNA ligase Cbei_1315 248 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 150019206 Nonpathogen - hypothetical protein Cbei_4395 1 None None None 150019728 Common - putative transcriptional regulator, TetR family Cbei_4920 1 COG1309 AcrR, Transcriptional regulator Transcription 150016461 Common - protein of unknown function DUF881 Cbei_1585 20 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 150018299 Common - oxidoreductase FAD/NAD(P)-binding domain protein Cbei_3472 103 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 150018232 Nonpathogen - response regulator receiver protein Cbei_3404 2 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 150019164 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Cbei_4352 210 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150019369 Common - phosphotransferase system PTS, sorbose-specific IIC subunit Cbei_4558 40 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150015814 Nonpathogen - hypothetical protein Cbei_0928 1 None None None 150019067 Common - export protein FliQ, family 3 Cbei_4255 1 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 150017787 Common - Domain of unknown function DUF1791 Cbei_2944 21 COG1416 COG1416, Uncharacterized conserved protein Function unknown 150017525 Common - hypothetical protein Cbei_2670 13 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 150015958 Common - Beta-ketoacyl synthase-like protein Cbei_1072 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150018913 Common - secretion protein HlyD family protein Cbei_4101 162 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150015041 Common - elongation factor Tu Cbei_0149 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 150015120 Common - Phosphomannomutase Cbei_0228 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150015810 Common - hypothetical protein Cbei_0924 20 None None None 150016836 Common - polysaccharide deacetylase Cbei_1964 87 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150016029 Common - peptide deformylase Cbei_1145 205 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 150015360 Common - periplasmic solute binding protein Cbei_0470 38 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150017908 Common - Rubrerythrin Cbei_3069 18 COG1592 COG1592, Rubrerythrin Energy production and conversion 150016313 Common - hypothetical protein Cbei_1433 57 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150015856 Common - peptidase M56, BlaR1 Cbei_0970 26 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 150019180 Nonpathogen - hypothetical protein Cbei_4368 3 None None None 150015643 Common - secreted protein containing uncharacterized conserved protein of ErfK family Cbei_0757 14 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150016733 Common - regulatory protein, ArsR Cbei_1860 155 COG0640 ArsR, Predicted transcriptional regulators Transcription 150016857 Common - (2Fe-2S)-binding domain protein Cbei_1985 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 150015304 Common - ATP synthase F0, B subunit Cbei_0414 77 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 150017021 Common - NADH:flavin oxidoreductase/NADH oxidase Cbei_2152 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150018660 Common - transferase hexapeptide repeat containing protein Cbei_3843 198 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150017253 Common - extracellular solute-binding protein, family 3 Cbei_2391 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150015024 Common - ribonuclease III Cbei_0132 36 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 150017920 Common - isopentenyl-diphosphate delta-isomerase, type 1 Cbei_3081 58 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 150018298 Common - putative signal transduction protein Cbei_3471 200 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 150016971 Common - hypothetical protein Cbei_2102 1 None None None 150018323 Common - hypothetical protein Cbei_3498 13 None None None 150015563 Common - Coenzyme F390 synthetase-like protein Cbei_0675 56 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 150015419 Common - Ribulose-phosphate 3-epimerase Cbei_0529 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150017915 Common - diguanylate cyclase Cbei_3076 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 150015032 Common - ribosomal protein L11 Cbei_0140 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 150018770 Nonpathogen - hypothetical protein Cbei_3958 2 None None None 150018911 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_4099 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018520 Common - ApbE family lipoprotein Cbei_3701 129 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150014904 Common - GCN5-related N-acetyltransferase Cbei_0012 39 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150016705 Common - glucuronate isomerase Cbei_1832 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 150017347 Common - hypothetical protein Cbei_2488 13 COG2388 COG2388, Predicted acetyltransferase General function prediction only 150017053 Common - diguanylate phosphodiesterase Cbei_2184 48 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 150016219 Common - hypothetical protein Cbei_1337 2 None None None 150018608 Common - membrane protein Cbei_3789 2 None None None 150016496 Nonpathogen - hypothetical protein Cbei_1620 1 None None None 150017462 Common - glycosyl transferase, family 2 Cbei_2604 80 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150016630 Nonpathogen - protein of unknown function DUF1284 Cbei_1756 13 COG3543 COG3543, Uncharacterized conserved protein Function unknown 150017316 Common - protein of unknown function DUF1312 Cbei_2456 7 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 150015062 Common rplO 50S ribosomal protein L15 Cbei_0170 217 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 150019660 Common - 6-phosphofructokinase Cbei_4852 156 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 150019518 Common - UDP-glucose 6-dehydrogenase Cbei_4708 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 150015742 Nonpathogen - hypothetical protein Cbei_0856 1 None None None 150015686 Common - peptidase M29, aminopeptidase II Cbei_0800 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 150016190 Common - UDP-N-acetylmuramyl-tripeptide synthetase Cbei_1308 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150019798 Common - RNA polymerase, sigma 32 subunit, RpoH Cbei_4990 204 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 150018746 Nonpathogen - hypothetical protein Cbei_3934 1 None None None 150016300 Common - hypothetical protein Cbei_1420 15 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 150015820 Common - ABC transporter related Cbei_0934 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150019874 Common - beta-lactamase domain protein Cbei_5066 127 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150016212 Common - ATP-dependent protease La Cbei_1330 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 150017932 Common - ABC transporter related Cbei_3093 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150017443 Common - glycosyl transferase, group 1 Cbei_2585 37 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150015783 Nonpathogen - hypothetical protein Cbei_0897 1 None None None 150018085 Nonpathogen - hypothetical protein Cbei_3254 1 None None None 150019034 Common - hypothetical protein Cbei_4222 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 150019511 Common - diguanylate cyclase Cbei_4701 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150016527 Nonpathogen - hypothetical protein Cbei_1651 1 None None None 150016577 Common - exodeoxyribonuclease VII, large subunit Cbei_1703 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 150018712 Common - transcriptional regulator, PadR-like family Cbei_3896 25 COG1695 COG1695, Predicted transcriptional regulators Transcription 150015197 Common - methyl-accepting chemotaxis sensory transducer Cbei_0307 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019767 Common - response regulator receiver protein Cbei_4959 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150015938 Common - hypothetical protein Cbei_1052 14 None None None 150019393 Common - hypothetical protein Cbei_4583 2 None None None 150015254 Nonpathogen - hypothetical protein Cbei_0364 1 None None None 150015890 Common - dihydroorotate dehydrogenase electron transfer subunit Cbei_1004 106 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150016056 Common - chromosome segregation protein SMC Cbei_1172 195 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150017796 Common - methyl-accepting chemotaxis sensory transducer Cbei_2953 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015819 Common - ABC transporter substrate-binding protein Cbei_0933 16 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150016011 Common - phosphate binding protein Cbei_1127 185 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 150016145 Common - ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Cbei_1263 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 150015438 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Cbei_0548 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 150019690 Common - Glutamine--scyllo-inositol transaminase Cbei_4882 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150014902 Common - FAD dependent oxidoreductase Cbei_0010 75 COG0579 COG0579, Predicted dehydrogenase General function prediction only 150018470 Common - transcriptional regulator, MarR family Cbei_3649 26 COG1846 MarR, Transcriptional regulators Transcription 150017029 Common - multi-sensor hybrid histidine kinase Cbei_2160 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016066 Common rnhB ribonuclease HII Cbei_1182 217 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 150016666 Common - protein of unknown function DUF1255 Cbei_1793 53 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 150017881 Common - protein of unknown function DUF323 Cbei_3040 65 COG1262 COG1262, Uncharacterized conserved protein Function unknown 150019224 Nonpathogen - hypothetical protein Cbei_4413 3 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 150014899 Common - DNA gyrase subunit A Cbei_0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 150018247 Common - hypothetical protein Cbei_3419 3 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 150017621 Common - inner-membrane translocator Cbei_2768 158 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 150015096 Common - butyrate kinase Cbei_0204 44 COG3426 COG3426, Butyrate kinase Energy production and conversion 150017993 Common - AAA ATPase Cbei_3158 5 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 150015457 Common - SpoVR family protein Cbei_0568 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 150017922 Common - nitroreductase Cbei_3083 96 COG0778 NfnB, Nitroreductase Energy production and conversion 150015029 Common rpmG 50S ribosomal protein L33 Cbei_0137 88 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 150017669 Nonpathogen - hypothetical protein Cbei_2818 1 None None None 150016458 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Cbei_1582 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 150015512 Common - nitrogenase iron protein Cbei_0623 117 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 150016628 Common - tryptophan synthase subunit beta Cbei_1754 228 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 150015751 Common - glycogen/starch/alpha-glucan phosphorylase Cbei_0865 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 150016966 Common - acyl-protein synthetase, LuxE Cbei_2097 17 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 150018488 Common - ABC transporter related Cbei_3668 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150017322 Common - Protein of unknown function DUF1722 Cbei_2462 57 COG3272 COG3272, Uncharacterized conserved protein Function unknown 150018343 Common - Aldose 1-epimerase Cbei_3518 17 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 150017531 Common - aldo/keto reductase Cbei_2676 183 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 150019291 Common - Gluconate transporter Cbei_4480 58 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 150019557 Nonpathogen - hypothetical protein Cbei_4748 1 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150017244 Common - Monosaccharide-transporting ATPase Cbei_2382 110 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 150016478 Common - GCN5-related N-acetyltransferase Cbei_1602 41 COG0456 RimI, Acetyltransferases General function prediction only 150018533 Nonpathogen - hypothetical protein Cbei_3714 1 None None None 150017576 Common - transcriptional regulator, XRE family Cbei_2723 12 COG1476 COG1476, Predicted transcriptional regulators Transcription 150015607 Common - phage replisome organizer, putative Cbei_0721 4 None None None 150017743 Common - transposase Cbei_2896 6 None None None 150017303 Common - YibE/F family protein Cbei_2443 23 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150015264 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_0374 26 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150019749 Common - extracellular solute-binding protein, family 1 Cbei_4941 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 150015765 Common - protein of unknown function DUF955 Cbei_0879 3 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 150015180 Common - protein of unknown function DUF886 Cbei_0290 4 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 150019638 Common - CheA signal transduction histidine kinase Cbei_4829 154 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 150016913 Common - hypothetical protein Cbei_2043 18 None None None 150017338 Common - transcriptional regulator, TetR family Cbei_2479 11 COG1309 AcrR, Transcriptional regulator Transcription 150015500 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Cbei_0611 9 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150017969 Nonpathogen - hypothetical protein Cbei_3131 1 None None None 150016921 Nonpathogen - hypothetical protein Cbei_2051 3 None None None 150016897 Nonpathogen - hypothetical protein Cbei_2026 1 None None None 150019509 Common - cell wall hydrolase/autolysin Cbei_4699 109 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150019626 Nonpathogen - hypothetical protein Cbei_4817 1 None None None 150019147 Common - ABC-3 protein Cbei_4335 190 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 150014920 Common - carbamoyl phosphate synthase small subunit Cbei_0028 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 150017778 Common - diguanylate cyclase Cbei_2933 174 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150019283 Common - metal dependent phosphohydrolase Cbei_4472 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150017058 Common - nitroreductase Cbei_2189 67 COG0778 NfnB, Nitroreductase Energy production and conversion 150018798 Common - SCP-like extracellular Cbei_3986 78 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150016282 Common - homocysteine S-methyltransferase Cbei_1402 181 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150015189 Common - polysaccharide deacetylase Cbei_0299 116 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150017930 Common hisS histidyl-tRNA synthetase Cbei_3091 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017976 Common - Cupin 2, conserved barrel domain protein Cbei_3138 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 150017700 Common - SCP-like extracellular Cbei_2851 78 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150019298 Common - thiamine-phosphate pyrophosphorylase Cbei_4487 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 150015158 Common - two component transcriptional regulator, LytTR family Cbei_0267 105 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150017613 Common - hypothetical protein Cbei_2760 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 150018812 Common - Ferredoxin hydrogenase Cbei_4000 49 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150017625 Common - ABC transporter related Cbei_2772 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150016586 Common - response regulator receiver protein Cbei_1712 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150019823 Common - StbA family protein Cbei_5015 17 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 150017696 Common - integral membrane sensor signal transduction histidine kinase Cbei_2846 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150014946 Common - peptidase M24 Cbei_0054 182 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150016294 Common - heat shock protein DnaJ domain protein Cbei_1414 208 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150018109 Common - coenzyme A transferase Cbei_3278 105 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 150015495 Common - ABC transporter related Cbei_0606 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150017612 Common - LamB/YcsF family protein Cbei_2759 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 150016940 Common - spore coat peptide assembly protein CotJB Cbei_2070 9 None None None 150015422 Common - transketolase Cbei_0532 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 150015301 Common - acetyl-CoA acetyltransferase Cbei_0411 188 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150018728 Common - transcriptional regulator, PadR-like family Cbei_3914 23 COG1695 COG1695, Predicted transcriptional regulators Transcription 150019648 Common - Aminoglycoside N(3')-acetyltransferase Cbei_4839 23 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 150019883 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Cbei_5075 202 COG0281 SfcA, Malic enzyme Energy production and conversion 150015174 Nonpathogen - hypothetical protein Cbei_0284 1 None None None 150016071 Common - transcriptional repressor CodY Cbei_1187 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 150019485 Common - glycoside hydrolase, family 30 Cbei_4675 23 COG5520 COG5520, O-Glycosyl hydrolase Cell envelope biogenesis, outer membrane 150019074 Common - flagellar hook capping protein Cbei_4262 57 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 150019656 Common - transcriptional regulator, RpiR family Cbei_4848 76 COG1737 RpiR, Transcriptional regulators Transcription 150016660 Common - 40-residue YVTN family beta-propeller repeat protein Cbei_1787 53 COG3391 COG3391, Uncharacterized conserved protein Function unknown 150017794 Common - two component transcriptional regulator, winged helix family Cbei_2951 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017831 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Cbei_2990 160 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 150018365 Common - Substrate-binding region of ABC-type glycine betaine transport system Cbei_3541 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 150017939 Common metH B12-dependent methionine synthase Cbei_3100 178 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150019375 Common - N-acetylglucosamine-6-phosphate deacetylase Cbei_4564 129 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 150018965 Common - ATP-dependent Clp protease adaptor protein ClpS Cbei_4153 117 COG2127 COG2127, Uncharacterized conserved protein Function unknown 150015084 Common - two component transcriptional regulator, winged helix family Cbei_0192 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016366 Common - protein of unknown function DUF6, transmembrane Cbei_1486 50 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150018704 Common - major facilitator superfamily MFS_1 Cbei_3888 60 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 150014980 Common - transcriptional regulator, AbrB family Cbei_0088 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150015104 Common - acetolactate synthase, small subunit Cbei_0212 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 150018871 Common - microcompartments protein Cbei_4059 16 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 150017019 Common - dihydroxyacetone kinase, phosphotransfer subunit Cbei_2150 45 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 150017838 Nonpathogen - hypothetical protein Cbei_2997 1 COG3462 COG3462, Predicted membrane protein Function unknown 150018616 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3797 127 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 150018930 Common - aminotransferase, class IV Cbei_4118 182 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150018493 Common - Penicillin amidase Cbei_3673 52 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 150017816 Common - protein of unknown function DUF214 Cbei_2973 113 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 150018696 Common - binding-protein-dependent transport systems inner membrane component Cbei_3880 84 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 150019322 Common - MIP family channel protein Cbei_4511 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 150015113 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_0221 19 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 150017044 Common - 2-isopropylmalate synthase Cbei_2175 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150017449 Common - glycosyl transferase, family 2 Cbei_2591 159 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150015059 Common rplR 50S ribosomal protein L18 Cbei_0167 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 150016816 Common - allantoate amidohydrolase Cbei_1944 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 150018720 Common - short-chain dehydrogenase/reductase SDR Cbei_3904 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150015632 Common - transposase IS116/IS110/IS902 family protein Cbei_0746 85 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150018649 Common - aldehyde dehydrogenase Cbei_3832 203 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150019573 Common - putative cell wall binding repeat-containing protein Cbei_4764 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019105 Common - hypothetical protein Cbei_4293 1 None None None 150015556 Common - methyl-accepting chemotaxis sensory transducer Cbei_0667 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017405 Common - Xanthine/uracil/vitamin C permease Cbei_2547 135 COG2252 COG2252, Permeases General function prediction only 150015008 Common - PSP1 domain protein Cbei_0116 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 150019465 Common - Alpha-glucosidase Cbei_4655 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 150019655 Common - glycoside hydrolase, family 4 Cbei_4847 53 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150018630 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_3811 30 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150017035 Nonpathogen - hypothetical protein Cbei_2166 1 None None None 150019138 Common - Rhomboid family protein Cbei_4326 146 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 150018102 Common - glycoside hydrolase, family 1 Cbei_3271 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150017184 Nonpathogen - metal dependent phosphohydrolase Cbei_2322 8 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150016603 Common - glycosyltransferase, MGT family Cbei_1729 54 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 150019502 Common - transcriptional regulator, TetR family Cbei_4692 99 COG1309 AcrR, Transcriptional regulator Transcription 150016548 Nonpathogen - hypothetical protein Cbei_1673 1 None None None 150018201 Common - Peptidoglycan-binding domain 1 protein Cbei_3373 35 COG3179 COG3179, Predicted chitinase General function prediction only 150016852 Common - protein of unknown function DUF182 Cbei_1980 114 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 150019151 Common - Nucleotidyl transferase Cbei_4339 46 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 150017703 Common - transcriptional regulator, TetR family Cbei_2854 17 COG1309 AcrR, Transcriptional regulator Transcription 150017606 Common gldA glycerol dehydrogenase Cbei_2753 71 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 150019140 Common - hypothetical protein Cbei_4328 2 None None None 150016930 Nonpathogen - hypothetical protein Cbei_2060 1 None None None 150015448 Common - hypothetical protein Cbei_0559 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 150015597 Common - PTS system, mannose/fructose/sorbose family, IIA subunit Cbei_0711 90 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150018819 Common - 2-keto-3-deoxygluconate permease Cbei_4007 27 COG2855 COG2855, Predicted membrane protein Function unknown 150016809 Common - iron-containing alcohol dehydrogenase Cbei_1937 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150016639 Common - ABC transporter related Cbei_1765 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150015997 Common - peptidase U32 Cbei_1113 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150017083 Common - helix-turn-helix domain protein Cbei_2215 4 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 150015109 Common - acetolactate synthase, large subunit, biosynthetic type Cbei_0217 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150018779 Common - two component transcriptional regulator, LytTR family Cbei_3967 87 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150017805 Common - protein of unknown function DUF134 Cbei_2962 42 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 150018801 Common - Beta-ketoacyl synthase-like protein Cbei_3989 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150015349 Common - regulatory protein, IclR Cbei_0459 122 COG1414 IclR, Transcriptional regulator Transcription 150015697 Common - hypothetical protein Cbei_0811 40 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 150016769 Common - LemA family protein Cbei_1896 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 150017275 Common - putative cell wall binding repeat-containing protein Cbei_2415 7 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 150017957 Common - methyl-accepting chemotaxis sensory transducer Cbei_3119 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016488 Common - SEC-C motif domain protein Cbei_1612 1 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 150014999 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Cbei_0107 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 150019053 Common - DNA-directed DNA polymerase Cbei_4241 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 150018564 Nonpathogen - hypothetical protein Cbei_3745 1 None None None 150017820 Common - SNARE associated Golgi protein Cbei_2978 21 COG0398 COG0398, Uncharacterized conserved protein Function unknown 150014987 Common - Septum formation initiator Cbei_0095 4 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 150017800 Common - cation diffusion facilitator family transporter Cbei_2957 207 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150016825 Common - aldehyde dehydrogenase Cbei_1953 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150018507 Nonpathogen - hypothetical protein Cbei_3687 1 COG4907 COG4907, Predicted membrane protein Function unknown 150016448 Common - tRNA/rRNA methyltransferase (SpoU) Cbei_1572 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150019010 Common - FeoA family protein Cbei_4198 5 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 150018863 Common - response regulator receiver protein Cbei_4051 219 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150015018 Common - DNA repair protein RadA Cbei_0126 205 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 150017436 Common - dTDP-glucose 4,6-dehydratase Cbei_2578 234 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 150018639 Common - short chain fatty acid transporter Cbei_3821 39 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 150019818 Common - sucrose-6-phosphate hydrolase Cbei_5010 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 150017412 Common - GCN5-related N-acetyltransferase Cbei_2554 15 COG0456 RimI, Acetyltransferases General function prediction only 150017176 Common - precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit Cbei_2314 87 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 150019906 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Cbei_5098 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 150019910 Common - protein of unknown function DUF37 Cbei_5102 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 150017219 Common - extracellular solute-binding protein, family 1 Cbei_2357 44 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016726 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Cbei_1853 119 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 150018292 Common - hypothetical protein Cbei_3465 13 None None None 150016557 Nonpathogen - hypothetical protein Cbei_1683 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 150017718 Common - Substrate-binding region of ABC-type glycine betaine transport system Cbei_2870 195 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 150018464 Common - nitroreductase Cbei_3643 58 COG0778 NfnB, Nitroreductase Energy production and conversion 150017646 Common - ABC transporter related Cbei_2794 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150019811 Common - Cyclopropane-fatty-acyl-phospholipid synthase Cbei_5003 139 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 150019057 Common - putative manganese-dependent inorganic pyrophosphatase Cbei_4245 56 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 150018894 Common - glucuronate isomerase Cbei_4082 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 150018735 Nonpathogen - hypothetical protein Cbei_3921 1 None None None 150017265 Common - putative CoA-substrate-specific enzyme activase Cbei_2405 64 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 150016457 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Cbei_1581 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 150016970 Common - nitrogen-fixing NifU domain protein Cbei_2101 93 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 150019120 Common - Protein-glutamate O-methyltransferase Cbei_4308 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 150017235 Common - putative transcriptional regulator, MerR family Cbei_2373 120 COG0789 SoxR, Predicted transcriptional regulators Transcription 150016020 Common - Sporulation stage IV, protein A Cbei_1136 15 COG0486 ThdF, Predicted GTPase General function prediction only 150017201 Common - phosphoesterase, PA-phosphatase related Cbei_2339 99 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 150015656 Common - binding-protein-dependent transport systems inner membrane component Cbei_0770 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150018623 Common - methyl-accepting chemotaxis sensory transducer Cbei_3804 111 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017829 Common - proton-translocating NADH-quinone oxidoreductase, chain L Cbei_2988 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 150016092 Common - polynucleotide phosphorylase/polyadenylase Cbei_1208 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 150017636 Common - response regulator receiver protein Cbei_2783 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150018009 Common - aspartate racemase Cbei_3176 84 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 150018159 Nonpathogen - type I phosphodiesterase/nucleotide pyrophosphatase Cbei_3330 23 COG3379 COG3379, Uncharacterized conserved protein Function unknown 150019476 Common - Lytic transglycosylase, catalytic Cbei_4666 164 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015282 Common - cyanophycinase Cbei_0392 34 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 150016592 Common - prophage ps3 protein 01, putative Cbei_1718 27 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 150017313 Common - RnfA-Nqr electron transport subunit Cbei_2453 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 150019303 Common - FMN-binding domain protein Cbei_4492 96 COG0348 NapH, Polyferredoxin Energy production and conversion 150019567 Common - glycosyl transferase, family 2 Cbei_4758 192 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150019431 Common - glycosyl transferase, group 1 Cbei_4621 90 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150018391 Common - UBA/Ts-N domain protein Cbei_3567 2 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 150017782 Nonpathogen - hypothetical protein Cbei_2938 1 None None None 150015456 Common - hypothetical protein Cbei_0567 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 150018185 Nonpathogen - hypothetical protein Cbei_3357 1 None None None 150015862 Common - GCN5-related N-acetyltransferase Cbei_0976 112 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 150017134 Nonpathogen - hypothetical protein Cbei_2271 1 None None None 150018205 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_3377 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015215 Common - 3-hydroxybutyryl-CoA dehydrogenase Cbei_0325 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 150019547 Common - Oligosaccharide biosynthesis protein Alg14-like protein Cbei_4737 20 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150016983 Common - inositol-5-monophosphate dehydrogenase Cbei_2114 234 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 150018954 Common - purine nucleoside phosphorylase Cbei_4142 100 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 150018793 Common - extracellular solute-binding protein, family 5 Cbei_3981 211 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 150015043 Common rplC 50S ribosomal protein L3 Cbei_0151 248 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 150015486 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Cbei_0597 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 150015473 Common - 6-phosphofructokinase Cbei_0584 158 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 150018384 Common - GCN5-related N-acetyltransferase Cbei_3560 18 COG0456 RimI, Acetyltransferases General function prediction only 150015293 Common - modification methylase, HemK family Cbei_0403 216 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 150016235 Common - hypothetical protein Cbei_1353 3 None None None 150017544 Common - hypothetical protein Cbei_2689 1 None None None 150017878 Common - ATP-dependent metalloprotease FtsH Cbei_3037 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150019082 Common flgC flagellar basal body rod protein FlgC Cbei_4270 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 150015398 Common rplU 50S ribosomal protein L21 Cbei_0508 156 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 150015927 Common - ABC transporter related Cbei_1041 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150018002 Common - Phosphoglycerate mutase Cbei_3168 55 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150018783 Common - Uncharacterized membrane-anchored protein Cbei_3971 11 COG4714 COG4714, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 150018435 Common - hypothetical protein Cbei_3613 23 COG4898 COG4898, Uncharacterized protein conserved in bacteria Function unknown 150015896 Common - pyruvate formate-lyase activating enzyme Cbei_1010 136 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150018970 Common - phosphotransferase system PTS, EIIB protein Cbei_4158 40 COG1264 PtsG, Phosphotransferase system IIB components Carbohydrate transport and metabolism 150015888 Common - dihydroorotase, multifunctional complex type Cbei_1002 214 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150019455 Common - putative transaldolase Cbei_4645 171 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150015101 Common - TrpR like protein, YerC/YecD Cbei_0209 20 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 150019699 Common - uracil-DNA glycosylase Cbei_4891 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 150015809 Common - Baseplate J family protein Cbei_0923 32 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150015056 Common rpsN 30S ribosomal protein S14 Cbei_0164 184 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 150015804 Common - hypothetical protein Cbei_0918 9 COG5412 COG5412, Phage-related protein Function unknown 150015943 Common - phosphoribosylaminoimidazole synthetase Cbei_1057 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 150015791 Common - hypothetical protein Cbei_0905 3 None None None 150015537 Common - thiamine monophosphate synthase Cbei_0648 77 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 150016541 Common - hypothetical protein Cbei_1665 1 None None None 150015151 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_0260 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150015759 Common - metallophosphoesterase Cbei_0873 8 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150018375 Common - hypothetical protein Cbei_3551 8 None None None 150015734 Common - putative signal-transduction protein with CBS domains Cbei_0848 26 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 150018833 Common - Cof-like hydrolase Cbei_4021 95 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150015624 Common - major facilitator superfamily MFS_1 Cbei_0738 80 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018380 Common - protein of unknown function UPF0027 Cbei_3556 120 COG1690 RtcB, Uncharacterized conserved protein Function unknown 150018996 Common - putative CheW protein Cbei_4184 124 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150017955 Common - Glutaredoxin-related protein Cbei_3116 7 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 150019710 Common - lipoprotein signal peptidase Cbei_4902 1 None None None 150018901 Common - hypothetical protein Cbei_4089 13 None None None 150019793 Common - transcriptional regulator, RpiR family Cbei_4985 94 COG1737 RpiR, Transcriptional regulators Transcription 150016943 Common - histidine kinase Cbei_2073 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150018826 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_4014 220 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 150019387 Common - 3-dehydroquinate synthase Cbei_4576 204 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 150015530 Nonpathogen - hypothetical protein Cbei_0641 1 COG4980 GvpP, Gas vesicle protein General function prediction only 150019024 Nonpathogen - hypothetical protein Cbei_4212 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 150019264 Common - transketolase Cbei_4453 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 150017212 Common - polysaccharide deacetylase Cbei_2350 117 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150019830 Common - hypothetical protein Cbei_5022 1 None None None 150017723 Common - acriflavin resistance protein Cbei_2875 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150019243 Common - Monosaccharide-transporting ATPase Cbei_4432 128 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 150016740 Common - protein of unknown function DUF1212 Cbei_1867 50 COG2966 COG2966, Uncharacterized conserved protein Function unknown 150016843 Common - YheO domain protein Cbei_1971 48 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 150015640 Common - toxic anion resistance family protein Cbei_0754 30 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 150016678 Common - two component transcriptional regulator, winged helix family Cbei_1805 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016957 Common - transcriptional activator, TenA family Cbei_2088 78 COG0819 TenA, Putative transcription activator Transcription 150018909 Common - amino acid permease-associated region Cbei_4097 54 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150014935 Common - integral membrane sensor signal transduction histidine kinase Cbei_0043 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016907 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Cbei_2037 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150017360 Common - HAD-superfamily hydrolase, subfamily IIA Cbei_2502 113 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 150018307 Common - Methyltransferase type 11 Cbei_3481 207 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150015709 Common - Stage II sporulation P family protein Cbei_0823 15 None None None 150018586 Common - FMN-binding domain protein Cbei_3767 8 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 150016596 Common - iron-containing alcohol dehydrogenase Cbei_1722 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150015544 Common - Cna B domain protein Cbei_0655 1 None None None 150018757 Common - metallophosphoesterase Cbei_3945 64 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150015611 Common - nitroreductase Cbei_0725 80 COG0778 NfnB, Nitroreductase Energy production and conversion 150015290 Common - Monogalactosyldiacylglycerol synthase Cbei_0400 23 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150015866 Common - nuclease SbcCD, D subunit Cbei_0980 112 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 150015332 Common - helix-turn-helix- domain containing protein, AraC type Cbei_0442 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016831 Common - transcriptional regulator, LysR family Cbei_1959 190 COG0583 LysR, Transcriptional regulator Transcription 150019665 Common - hypothetical protein Cbei_4857 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 150019873 Common - protein of unknown function DUF606 Cbei_5065 18 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 150016900 Common - K+ potassium transporter Cbei_2029 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 150016122 Common - protein of unknown function DUF479 Cbei_1238 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 150019233 Common - Alanine racemase Cbei_4422 129 COG1609 PurR, Transcriptional regulators Transcription 150015609 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_0723 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150018656 Common - protein of unknown function DUF205 Cbei_3839 169 COG0344 COG0344, Predicted membrane protein Function unknown 150017238 Common - isochorismatase hydrolase Cbei_2376 118 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 150017429 Nonpathogen - hypothetical protein Cbei_2571 1 None None None 150016309 Common - glutaminyl-tRNA synthetase Cbei_1429 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150017433 Common - putative prophage repressor Cbei_2575 170 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150015232 Common - hypothetical protein Cbei_0342 89 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 150018516 Common - hypothetical protein Cbei_3697 11 None None None 150015372 Common - phage shock protein A, PspA Cbei_0482 86 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 150019402 Common - integral membrane sensor signal transduction histidine kinase Cbei_4592 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150017533 Common - Pirin domain protein Cbei_2678 146 COG1741 COG1741, Pirin-related protein General function prediction only 150015834 Common - hypothetical protein Cbei_0948 2 None None None 150018986 Common - response regulator receiver Cbei_4174 195 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 150016048 Common eutD phosphotransacetylase Cbei_1164 165 COG0280 Pta, Phosphotransacetylase Energy production and conversion 150016607 Common - hypothetical protein Cbei_1733 1 None None None 150015039 Common - 30S ribosomal protein S7 Cbei_0147 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 150018431 Common - phage integrase family protein Cbei_3609 37 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150016047 Common - protein of unknown function DUF795 Cbei_1163 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 150019340 Common - pyridine nucleotide-disulphide oxidoreductase Cbei_4529 40 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 150019013 Nonpathogen - hypothetical protein Cbei_4201 1 None None None 150015205 Common - pyruvate formate-lyase Cbei_0315 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150016861 Common - molybdenum cofactor biosynthesis protein A Cbei_1989 205 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 150015700 Common - sporulation sigma factor SigF Cbei_0814 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150016161 Common - Homoserine O-succinyltransferase Cbei_1279 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 150018144 Common - transcriptional regulator, HxlR family Cbei_3315 147 COG1733 COG1733, Predicted transcriptional regulators Transcription 150018572 Nonpathogen - S-adenosylmethionine-dependent methyltransferase Cbei_3753 3 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150017864 Common - hypothetical protein Cbei_3023 49 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150016931 Common - ammonium transporter Cbei_2061 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 150016614 Common - ribonuclease Z Cbei_1740 108 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 150018017 Common - Methionine--tRNA ligase Cbei_3185 161 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150016109 Common - riboflavin synthase subunit alpha Cbei_1225 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 150014915 Common - channel protein, hemolysin III family Cbei_0023 118 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 150018690 Common - PTS system, mannose/fructose/sorbose family, IIA subunit Cbei_3874 87 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150019343 Common - PTS system, N-acetylglucosamine-specific IIBC subunit Cbei_4532 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150016359 Common - transcriptional regulator, RpiR family Cbei_1479 74 COG1737 RpiR, Transcriptional regulators Transcription 150015143 Common - Erythronolide synthase., Aspartate racemase Cbei_0251 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150019310 Common - L-serine dehydratase, iron-sulfur-dependent, beta subunit Cbei_4499 123 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 150018824 Common - methyl-accepting chemotaxis sensory transducer Cbei_4012 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019111 Common - FlgN family protein Cbei_4299 1 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 150015302 Common - F0F1 ATP synthase subunit A Cbei_0412 168 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 150018468 Nonpathogen - hypothetical protein Cbei_3647 1 None None None 150019367 Common - sugar isomerase (SIS) Cbei_4556 100 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 150019462 Common - Cof-like hydrolase Cbei_4652 125 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150019533 Common - putative cell wall binding repeat-containing protein Cbei_4723 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018115 Common - hypothetical protein Cbei_3285 4 None None None 150015371 Common - hypothetical protein Cbei_0481 1 None None None 150018227 Nonpathogen - hypothetical protein Cbei_3399 1 None None None 150016350 Common - Extradiol ring-cleavage dioxygenase, class III protein, subunit B Cbei_1470 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 150016562 Nonpathogen - hypothetical protein Cbei_1688 1 None None None 150018922 Common - hydrogenase, Fe-only Cbei_4110 187 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150019093 Common - acylneuraminate cytidylyltransferase Cbei_4281 39 COG1861 SpsF, Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog Cell envelope biogenesis, outer membrane 150017792 Common - uncharacterized conserved protein, CotF B.subtilis family Cbei_2949 5 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 150018424 Common - GCN5-related N-acetyltransferase Cbei_3602 61 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150019746 Common - Ornithine carbamoyltransferase Cbei_4938 210 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 150018699 Common - hypothetical protein Cbei_3883 110 COG1511 COG1511, Predicted membrane protein Function unknown 150018194 Common - regulatory protein, LacI Cbei_3366 128 COG1609 PurR, Transcriptional regulators Transcription 150016995 Common aspC aspartyl-tRNA synthetase Cbei_2126 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150019275 Common - response regulator receiver protein Cbei_4464 220 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150016742 Common - isochorismatase hydrolase Cbei_1869 5 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 150014966 Common - metal dependent phosphohydrolase Cbei_0074 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150018546 Nonpathogen - hypothetical protein Cbei_3727 1 None None None 150017106 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cbei_2239 12 COG5015 COG5015, Uncharacterized conserved protein Function unknown 150016819 Common - Zn-dependent hydrolase of the beta-lactamase fold-like protein Cbei_1947 83 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150018171 Common - D-galactose-binding periplasmic protein precursor Cbei_3343 55 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016248 Nonpathogen - hypothetical protein Cbei_1366 1 None None None 150019326 Common - argininosuccinate synthase Cbei_4515 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 150016040 Common - protein of unknown function DUF322 Cbei_1156 33 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 150018459 Common - transcriptional regulator, MarR family Cbei_3637 54 COG1846 MarR, Transcriptional regulators Transcription 150015015 Common - ATPase AAA-2 domain protein Cbei_0123 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150016188 Common - methionine sulfoxide reductase A Cbei_1306 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150016026 Common rpoZ DNA-directed RNA polymerase subunit omega Cbei_1142 25 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 150017891 Common - metal dependent phosphohydrolase Cbei_3051 120 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150019069 Common - putative flagellar formation protein Cbei_4257 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 150017186 Common - protein of unknown function DUF1540 Cbei_2324 3 None None None 150018686 Common - Glycosyl hydrolase family 32, N terminal domain protein Cbei_3870 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 150015847 Common - PHP C-terminal domain protein Cbei_0961 80 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 150017651 Common - hypothetical protein Cbei_2799 11 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 150019713 Common glgC glucose-1-phosphate adenylyltransferase Cbei_4905 226 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 150016337 Common - hypothetical protein Cbei_1457 4 None None None 150016891 Common - bacterocin transport accessory protein Cbei_2019 4 None None None 150016014 Common - phosphate ABC transporter, ATPase subunit Cbei_1130 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 150016076 Common - undecaprenyl diphosphate synthase Cbei_1192 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 150018765 Common - methyl-accepting chemotaxis sensory transducer Cbei_3953 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016389 Common - GntR domain protein Cbei_1511 143 COG2186 FadR, Transcriptional regulators Transcription 150019136 Common - DNA topoisomerase IV subunit B Cbei_4324 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 150015392 Common - hypothetical protein Cbei_0502 2 None None None 150018447 Common - methyl-accepting chemotaxis sensory transducer Cbei_3625 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015343 Common - transcriptional regulator, DeoR family Cbei_0453 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150016429 Common - multi-sensor signal transduction histidine kinase Cbei_1553 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017679 Common - putative RNA polymerase sigma factor SigI Cbei_2829 15 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150018777 Nonpathogen - Accessory gene regulator B Cbei_3965 1 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150019305 Common - ApbE family lipoprotein Cbei_4494 119 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150016124 Common - hypothetical protein Cbei_1240 6 None None None 150015386 Common minC septum formation inhibitor Cbei_0496 105 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 150016716 Common - 1-phosphofructokinase Cbei_1843 102 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 150017169 Nonpathogen - hypothetical protein Cbei_2307 1 None None None 150018440 Common - transcriptional regulator, TetR family Cbei_3618 5 COG1309 AcrR, Transcriptional regulator Transcription 150015328 Nonpathogen - hypothetical protein Cbei_0438 1 None None None 150017009 Common - transport system permease protein Cbei_2140 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150018142 Nonpathogen - hypothetical protein Cbei_3313 1 None None None 150016799 Common - NADH:flavin oxidoreductase/NADH oxidase Cbei_1927 181 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150015787 Nonpathogen - hypothetical protein Cbei_0901 1 None None None 150019834 Common - two component transcriptional regulator, winged helix family Cbei_5026 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150018010 Common - transcriptional regulator, LysR family Cbei_3177 193 COG0583 LysR, Transcriptional regulator Transcription 150017077 Common - GCN5-related N-acetyltransferase Cbei_2208 43 COG0456 RimI, Acetyltransferases General function prediction only 150019861 Common - transcriptional regulator, BadM/Rrf2 family Cbei_5053 102 COG1959 COG1959, Predicted transcriptional regulator Transcription 150016871 Common - nitrogenase iron protein Cbei_1999 104 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 150015184 Common - methyl-accepting chemotaxis sensory transducer Cbei_0294 115 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017588 Common - NADPH-dependent FMN reductase Cbei_2735 48 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150018153 Common - lantibiotic permease protein spaE/mutE Cbei_3324 6 None None None 150015355 Common - Rubredoxin-type Fe(Cys)4 protein Cbei_0465 122 COG1773 COG1773, Rubredoxin Energy production and conversion 150016533 Common - hypothetical protein Cbei_1657 17 None None None 150014940 Common - transcriptional regulator, TrmB Cbei_0048 108 COG1846 MarR, Transcriptional regulators Transcription 150017853 Common - nickel-dependent hydrogenase, large subunit Cbei_3012 105 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 150015974 Common - hypothetical protein Cbei_1089 1 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150018124 Common - ABC-type sugar transport system, periplasmic component Cbei_3295 49 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019169 Common - nitroreductase Cbei_4357 94 COG0778 NfnB, Nitroreductase Energy production and conversion 150016569 Common - Sporulation stage III, protein AD Cbei_1695 15 None None None 150017619 Common - ABC transporter related Cbei_2766 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150018998 Common - sulfate adenylyltransferase, large subunit Cbei_4186 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 150019089 Common - glycosyltransferase Cbei_4277 36 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 150018452 Common - acetyl-CoA acetyltransferase Cbei_3630 188 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150017681 Common - Carbohydrate-binding family V/XII Cbei_2831 25 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 150016475 Common - Fibronectin-binding A domain protein Cbei_1599 82 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 150016524 Common - hypothetical protein Cbei_1648 5 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 150018052 Common - aspartate ammonia-lyase Cbei_3220 238 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 150017151 Nonpathogen - hypothetical protein Cbei_2289 1 None None None 150016237 Common - hypothetical protein Cbei_1355 3 None None None 150016329 Common - heavy metal translocating P-type ATPase Cbei_1449 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150017985 Common - outer membrane protein expression inhibitor Cbei_3150 91 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150015320 Common - hypothetical protein Cbei_0430 1 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 150015879 Common - Delta-lactam-biosynthetic de-N-acetylase Cbei_0993 106 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150016758 Common - regulatory protein GntR, HTH Cbei_1885 141 COG1725 COG1725, Predicted transcriptional regulators Transcription 150019319 Common - FAD dependent oxidoreductase Cbei_4508 144 COG0579 COG0579, Predicted dehydrogenase General function prediction only 150016316 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_1436 142 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150017061 Common - 6-phosphogluconate dehydrogenase-like protein Cbei_2192 172 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 150015224 Common - transcriptional antiterminator, BglG Cbei_0334 32 COG3711 BglG, Transcriptional antiterminator Transcription 150016433 Common - transcriptional regulator, CarD family Cbei_1557 81 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 150018473 Common - extracellular solute-binding protein, family 3 Cbei_3652 152 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150017142 Common - Rubredoxin-type Fe(Cys)4 protein Cbei_2279 123 COG1773 COG1773, Rubredoxin Energy production and conversion 150017394 Common - membrane-bound metal-dependent hydrolase Cbei_2536 22 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 150016321 Common - binding-protein-dependent transport systems inner membrane component Cbei_1441 149 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150017786 Common - hypothetical protein Cbei_2943 3 None None None 150017811 Common - DoxX family protein Cbei_2968 13 None None None 150018068 Common - putative cell wall binding repeat-containing protein Cbei_3237 15 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015983 Common - nitrogen-fixing NifU domain protein Cbei_1099 157 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 150018110 Common - cation diffusion facilitator family transporter Cbei_3279 205 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150015571 Common - Radical SAM domain protein Cbei_0683 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150019605 Common - Threonyl/alanyl tRNA synthetase, SAD Cbei_4796 229 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017670 Common - hypothetical protein Cbei_2819 9 None None None 150018043 Nonpathogen - hypothetical protein Cbei_3211 1 None None None 150015963 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Cbei_1077 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 150016127 Common - hypothetical protein Cbei_1243 8 None None None 150015561 Common - transposase, mutator type Cbei_0672 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 150015425 Common - integral membrane sensor signal transduction histidine kinase Cbei_0535 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016593 Common - Phosphoglycerate mutase Cbei_1719 198 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150016685 Common - histidinol-phosphate aminotransferase Cbei_1812 237 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150017283 Common - hypothetical protein Cbei_2423 9 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018353 Common - transcriptional regulator, BadM/Rrf2 family Cbei_3529 168 COG1959 COG1959, Predicted transcriptional regulator Transcription 150017355 Common - sigma-54 factor, interaction domain-containing protein Cbei_2497 164 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 150017565 Common - transcriptional antiterminator, BglG Cbei_2711 32 COG3711 BglG, Transcriptional antiterminator Transcription 150016779 Nonpathogen - hypothetical protein Cbei_1907 1 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 150018946 Common - hypothetical protein Cbei_4134 7 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 150019528 Common - putative cell wall binding repeat-containing protein Cbei_4718 7 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018266 Common - major facilitator superfamily MFS_1 Cbei_3439 102 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150017602 Common - conserved hypothetical membrane spanning protein Cbei_2749 5 COG4296 COG4296, Uncharacterized protein conserved in bacteria Function unknown 150018347 Common - Citrate transporter Cbei_3522 11 COG2851 CitM, H+/citrate symporter Energy production and conversion 150015131 Common - Cystathionine gamma-synthase Cbei_0239 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150017336 Common - acriflavin resistance protein Cbei_2477 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150018321 Common - FAD linked oxidase domain protein Cbei_3496 46 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150015022 Common - prolyl-tRNA synthetase Cbei_0130 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150017906 Common - hypothetical protein Cbei_3066 8 COG5298 COG5298, Uncharacterized protein conserved in bacteria Function unknown 150018827 Common - response regulator receiver protein Cbei_4015 203 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016414 Common secD preprotein translocase subunit SecD Cbei_1536 220 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 150015030 Common secE preprotein translocase subunit SecE Cbei_0138 8 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 150015641 Common - putative CheW protein Cbei_0755 183 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150016060 Common - ribosomal protein S16 Cbei_1176 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 150015498 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Cbei_0609 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150019618 Common - amidohydrolase Cbei_4809 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150017121 Nonpathogen - hypothetical protein Cbei_2256 1 None None None 150019208 Nonpathogen - Molecular chaperone-like protein Cbei_4397 1 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 150016699 Common - putative RNA polymerase sigma factor SigI Cbei_1826 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150019395 Common - NADPH-dependent FMN reductase Cbei_4585 35 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150017917 Common - PAS/PAC sensor hybrid histidine kinase Cbei_3078 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017473 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_2617 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150019397 Nonpathogen - hypothetical protein Cbei_4587 1 None None None 150015299 Common - CMP/dCMP deaminase, zinc-binding Cbei_0409 64 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 150019855 Nonpathogen - hypothetical protein Cbei_5047 1 None None None 150017721 Common - polysaccharide deacetylase Cbei_2873 85 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150018105 Common - transcriptional antiterminator, BglG Cbei_3274 29 COG3711 BglG, Transcriptional antiterminator Transcription 150016735 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase Cbei_1862 107 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 150015761 Common - methyl-accepting chemotaxis sensory transducer Cbei_0875 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017110 Common - transcriptional regulator, HxlR family Cbei_2244 137 COG1733 COG1733, Predicted transcriptional regulators Transcription 150016013 Common - phosphate ABC transporter, inner membrane subunit PstA Cbei_1129 228 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 150017997 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3162 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150019352 Common - fructose-1,6-bisphosphatase Cbei_4541 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 150017255 Common - L-asparaginase, type II Cbei_2395 138 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 150018596 Common - putative small multidrug resistance transmembrane protein Cbei_3777 12 None None None 150016467 Common - RNA-binding S4 domain protein Cbei_1591 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 150015464 Common - hypothetical protein Cbei_0575 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150015417 Common - PTS system, mannitol-specific IIC subunit Cbei_0527 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 150015491 Common eno phosphopyruvate hydratase Cbei_0602 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 150018606 Common - hypothetical protein Cbei_3787 5 None None None 150019513 Common - transcriptional regulator, RpiR family Cbei_4703 33 COG1737 RpiR, Transcriptional regulators Transcription 150016521 Common - hypothetical protein Cbei_1645 2 None None None 150017345 Common - ribonuclease H Cbei_2486 154 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 150015178 Common - Rubrerythrin Cbei_0288 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 150019177 Common - hypothetical protein Cbei_4365 2 None None None 150015195 Common - iron-containing alcohol dehydrogenase Cbei_0305 216 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150015744 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_0858 6 None None None 150016910 Common - coenzyme A transferase Cbei_2040 102 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 150019876 Common - primosome, DnaD subunit Cbei_5068 9 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150017716 Common - transcriptional regulator, LysR family Cbei_2867 192 COG0583 LysR, Transcriptional regulator Transcription 150016888 Common - hypothetical protein Cbei_2016 1 None None None 150016176 Common - homoserine kinase Cbei_1294 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 150015774 Common - putative prophage LambdaCh01, transcriptional regulator Cbei_0888 2 None None None 150018401 Common - transcriptional regulator, TetR family Cbei_3577 20 COG1309 AcrR, Transcriptional regulator Transcription 150017000 Common - putative cell wall binding repeat-containing protein Cbei_2131 5 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019597 Common - enzyme with TIM-barrel fold Cbei_4788 8 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 150017739 Common - glycoside hydrolase, family 31 Cbei_2891 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 150015368 Common - DNA mismatch repair protein MutS domain protein Cbei_0478 196 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150017396 Common - 6-pyruvoyl tetrahydrobiopterin synthase, putative Cbei_2538 82 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 150016499 Common - primosome, DnaD subunit Cbei_1623 9 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150015793 Common - phage portal protein Cbei_0907 18 COG4695 COG4695, Phage-related protein Function unknown 150016289 Common - putative aminopeptidase 1 Cbei_1409 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 150016153 Common - putative ATP binding protein Cbei_1271 53 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 150019170 Common - transcriptional regulator, AraC family Cbei_4358 116 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016529 Common - hypothetical protein Cbei_1653 2 None None None 150017460 Common - glucose-1-phosphate thymidylyltransferase Cbei_2602 235 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150015968 Common - putative cell wall binding repeat-containing protein Cbei_1082 2 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017080 Common - NADPH-dependent FMN reductase Cbei_2211 44 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150015233 Common - Two component regulator three Y domain protein Cbei_0343 1 None None None 150016492 Common - transcriptional regulator, XRE family Cbei_1616 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 150018328 Common - response regulator receiver protein Cbei_3503 201 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150019540 Common - glycosyl transferase, group 1 Cbei_4730 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150018918 Common - secreted protein containing uncharacterized conserved protein of ErfK family Cbei_4106 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 150017296 Common - metal dependent phosphohydrolase Cbei_2436 45 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 150017763 Common - efflux transporter, RND family, MFP subunit Cbei_2918 185 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150019791 Common - PTS system, glucose-like IIB subunint Cbei_4983 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150018271 Nonpathogen - hypothetical protein Cbei_3444 1 None None None 150019041 Common - Sporulation protein YunB Cbei_4229 14 None None None 150016004 Common - sporulation sigma factor SigE Cbei_1120 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150018805 Common - D-galactose-binding periplasmic protein precursor Cbei_3993 43 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016112 Common - regulatory protein, LacI Cbei_1228 126 COG1609 PurR, Transcriptional regulators Transcription 150016729 Common - Superoxide dismutase Cbei_1856 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 150015785 Nonpathogen - hypothetical protein Cbei_0899 1 None None None 150018708 Common - conserved uncharacterized protein Cbei_3892 2 None None None 150017415 Common xerC site-specific tyrosine recombinase XerC Cbei_2557 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150018035 Common - DNA polymerase III, alpha subunit Cbei_3203 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 150019428 Common - UTP-glucose-1-phosphate uridylyltransferase Cbei_4618 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150016397 Common thiG thiazole synthase Cbei_1519 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 150017490 Nonpathogen - hypothetical protein Cbei_2634 2 None None None 150015064 Common adk adenylate kinase Cbei_0172 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 150015283 Common - cyanophycin synthetase Cbei_0393 127 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150016644 Common - major facilitator superfamily MFS_1 Cbei_1770 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150015134 Common - PTS system, mannitol-specific IIC subunit Cbei_0242 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 150017467 Common - pantoate--beta-alanine ligase Cbei_2609 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 150016203 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Cbei_1321 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 150019447 Common - hypothetical protein Cbei_4637 2 None None None 150018503 Common - cell wall-associated hydrolase-like protein Cbei_3683 4 COG3863 COG3863, Uncharacterized distant relative of cell wall-associated hydrolases Function unknown 150015720 Common prmA ribosomal protein L11 methyltransferase Cbei_0834 177 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 150015690 Common - methyl-accepting chemotaxis sensory transducer Cbei_0804 130 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015568 Common - O-methyltransferase, family 3 Cbei_0680 59 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 150015167 Common - cyclase family protein Cbei_0277 16 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 150016597 Common - methyl-accepting chemotaxis sensory transducer Cbei_1723 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017164 Common - hypothetical protein Cbei_2302 1 None None None 150019019 Common - aspartate kinase Cbei_4207 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 150016555 Nonpathogen - hypothetical protein Cbei_1680 1 None None None 150016657 Common - FolC bifunctional protein Cbei_1784 219 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 150019287 Common - transcriptional regulator, CdaR Cbei_4476 42 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 150014973 Common - UDP-N-acetylglucosamine pyrophosphorylase Cbei_0081 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 150019777 Common - nitroreductase Cbei_4969 83 COG0778 NfnB, Nitroreductase Energy production and conversion 150018337 Common - 2,5-didehydrogluconate reductase Cbei_3512 170 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 150015736 Common - Spore coat protein CotS Cbei_0850 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 150015516 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Cbei_0627 33 COG1433 COG1433, Uncharacterized conserved protein Function unknown 150016095 Common - aspartate kinase I Cbei_1211 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 150016890 Common - putative transcriptional regulator, MerR family Cbei_2018 107 COG0789 SoxR, Predicted transcriptional regulators Transcription 150019734 Common - uncharacterised conserved protein UCP033563 Cbei_4926 45 COG4198 COG4198, Uncharacterized conserved protein Function unknown 150019577 Nonpathogen - hypothetical protein Cbei_4768 1 None None None 150015248 Common - hypothetical protein Cbei_0358 7 None None None 150017707 Nonpathogen - hypothetical protein Cbei_2858 2 None None None 150019429 Common - oxidoreductase domain protein Cbei_4619 191 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150016245 Nonpathogen - hypothetical protein Cbei_1363 1 None None None 150016050 Common - protein of unknown function DUF177 Cbei_1166 44 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 150019569 Common - putative cell wall binding repeat-containing protein Cbei_4760 4 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016485 Nonpathogen - hypothetical protein Cbei_1609 1 None None None 150015728 Common - metal dependent phosphohydrolase Cbei_0842 57 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 150017973 Common - D-galactose-binding periplasmic protein precursor Cbei_3135 79 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018059 Common - Endoribonuclease L-PSP Cbei_3227 6 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 150018277 Common - transposase (21) Cbei_3450 16 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 150019683 Common - carbohydrate kinase, YjeF related protein Cbei_4875 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 150017310 Common - electron transport complex, RnfABCDGE type, D subunit Cbei_2450 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 150018187 Common - two component transcriptional regulator, winged helix family Cbei_3359 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015634 Common - deoxyribose-phosphate aldolase Cbei_0748 136 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 150019506 Common - putative cell wall binding repeat-containing protein Cbei_4696 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019060 Common - hypothetical protein Cbei_4248 1 None None None 150019048 Common - glycosyl transferase, family 2 Cbei_4236 201 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150016381 Nonpathogen - hypothetical protein Cbei_1503 1 None None None 150016156 Common - Sporulation protein YtaF Cbei_1274 15 COG1971 COG1971, Predicted membrane protein Function unknown 150016468 Common - DivIVA family protein Cbei_1592 30 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 150016690 Common - hypothetical protein Cbei_1817 23 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 150017115 Common - histidine kinase Cbei_2250 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150015653 Common - response regulator receiver protein Cbei_0767 222 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150017732 Common - FAD linked oxidase domain protein Cbei_2884 203 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150019560 Common - ABC-2 type transporter Cbei_4751 111 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150019896 Common - MscS Mechanosensitive ion channel Cbei_5088 223 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150015431 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cbei_0541 57 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 150018579 Common - ABC transporter related Cbei_3760 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150015746 Common - transglutaminase domain protein Cbei_0860 8 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 150018495 Common - RNA polymerase factor sigma-70 Cbei_3675 14 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150016840 Common - hypothetical protein Cbei_1968 229 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 150017227 Common - HAD-superfamily hydrolase, subfamily IIA Cbei_2365 97 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 150014953 Common - hypothetical protein Cbei_0061 1 None None None 150018300 Common - CDP-alcohol phosphatidyltransferase Cbei_3473 42 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 150018553 Nonpathogen - hypothetical protein Cbei_3734 1 None None None 150018074 Common - small GTP-binding protein Cbei_3243 200 COG1160 COG1160, Predicted GTPases General function prediction only 150019422 Common - Coat F domain protein Cbei_4612 4 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 150016516 Nonpathogen - hypothetical protein Cbei_1640 2 COG5471 COG5471, Uncharacterized conserved protein Function unknown 150017384 Common - hypothetical protein Cbei_2526 3 None None None 150019469 Common - mannonate dehydratase Cbei_4659 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 150017370 Common - ABC transporter related Cbei_2512 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150015163 Common - NADPH-dependent FMN reductase Cbei_0273 42 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150017960 Common - inner-membrane translocator Cbei_3122 107 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 150019697 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_4889 159 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150016752 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cbei_1879 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150017967 Common - uridine phosphorylase Cbei_3129 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 150017734 Common - Electron transfer flavoprotein, alpha subunit-like protein Cbei_2886 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150018632 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_3813 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150018100 Common - hypothetical protein Cbei_3269 9 None None None 150019076 Common - flagellar export protein FliJ Cbei_4264 3 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 150017807 Common - Abortive infection protein Cbei_2964 13 None None None 150018963 Common - hypothetical protein Cbei_4151 14 None None None 150018789 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cbei_3977 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 150019675 Common - protein of unknown function DUF214 Cbei_4867 112 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 150019641 Common - methyl-accepting chemotaxis sensory transducer Cbei_4832 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150017662 Common - type III restriction protein, res subunit Cbei_2810 157 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 150018865 Common - iron-containing alcohol dehydrogenase Cbei_4053 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150018647 Nonpathogen - hypothetical protein Cbei_3830 1 None None None 150017402 Common cmk cytidylate kinase Cbei_2544 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 150018156 Common - protein of unknown function DUF21 Cbei_3327 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150016878 Common - ferredoxin, 2Fe-2S Cbei_2006 96 COG3411 COG3411, Ferredoxin Energy production and conversion 150019642 Common - glycoside hydrolase, family 1 Cbei_4833 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150016360 Common - two component transcriptional regulator, LytTR family Cbei_1480 223 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150018932 Common - glutamine amidotransferase of anthranilate synthase Cbei_4120 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 150016130 Common - hypothetical protein Cbei_1246 71 COG3885 COG3885, Uncharacterized conserved protein Function unknown 150019103 Common - flagellar hook-associated 2 domain protein Cbei_4291 22 COG1345 FliD, Flagellar capping protein Cell motility and secretion 150017802 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Cbei_2959 177 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 150015595 Common - Uroporphyrinogen decarboxylase (URO-D) Cbei_0709 21 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 150015999 Common - sporulation sigma factor SigK Cbei_1115 214 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 150019635 Common - response regulator receiver modulated CheB methylesterase Cbei_4826 181 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 150016368 Common - hypothetical protein Cbei_1489 15 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 150018817 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cbei_4005 191 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150018614 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3795 162 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 150017604 Nonpathogen - hypothetical protein Cbei_2751 1 None None None 150018722 Common - Acetyltransferase including N-acetylase of ribosomal -like protein Cbei_3907 52 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150019370 Common - PTS system sorbose subfamily IIB component Cbei_4559 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150019487 Common - integral membrane sensor signal transduction histidine kinase Cbei_4677 105 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150016272 Common - methyl-accepting chemotaxis sensory transducer Cbei_1391 36 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018367 Common - O-acetylhomoserine aminocarboxypropyltransferase Cbei_3543 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150019128 Common - aminotransferase, class I and II Cbei_4316 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150016827 Common - transcriptional regulator, MarR family Cbei_1955 25 COG1846 MarR, Transcriptional regulators Transcription 150015703 Common - Sporulation stage V, protein AE Cbei_0817 15 None None None 150016763 Common - transcriptional regulator, RpiR family Cbei_1890 95 COG1737 RpiR, Transcriptional regulators Transcription 150015695 Common - TspO and MBR like protein Cbei_0809 64 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 150017637 Nonpathogen - hypothetical protein Cbei_2784 2 None None None 150019055 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cbei_4243 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150016376 Common - hypothetical protein Cbei_1498 4 None None None 150017822 Common - multicopper oxidase, type 3 Cbei_2980 133 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 150017085 Common - phage replisome organizer, putative Cbei_2217 4 None None None 150017590 Common - leucyl aminopeptidase Cbei_2737 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 150015316 Common - protein of unknown function DUF1256 Cbei_0426 14 None None None 150014926 Common - hypothetical protein Cbei_0034 1 None None None 150017012 Common - transcriptional regulator, LysR family Cbei_2143 193 COG0583 LysR, Transcriptional regulator Transcription 150015410 Common - competence protein ComEA helix-hairpin-helix repeat protein Cbei_0520 97 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 150016807 Common - transcriptional regulator, PucR family Cbei_1935 29 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 150017120 Nonpathogen - hypothetical protein Cbei_2255 1 None None None 150016518 Nonpathogen - hypothetical protein Cbei_1642 2 None None None 150019337 Common - transcriptional regulator, GntR family Cbei_4526 80 COG2188 PhnF, Transcriptional regulators Transcription 150015086 Common - ribonucleotide-diphosphate reductase subunit alpha Cbei_0194 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 150017063 Common - iron-containing alcohol dehydrogenase Cbei_2194 46 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 150016854 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Cbei_1982 123 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150017018 Common - dihydroxyacetone kinase, L subunit Cbei_2149 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 150017453 Nonpathogen - hypothetical protein Cbei_2595 1 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 150016137 Common - ATP-dependent protease La Cbei_1254 217 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 150018634 Common - transcriptional regulator, GntR family Cbei_3815 102 COG2188 PhnF, Transcriptional regulators Transcription 150017034 Common - hemerythrin-like metal-binding protein Cbei_2165 34 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 150019377 Common - Beta-glucosidase Cbei_4566 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 150016504 Nonpathogen - hypothetical protein Cbei_1628 1 None None None 150019631 Common - putative CheW protein Cbei_4822 130 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150017511 Common - MATE efflux family protein Cbei_2656 177 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150017837 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Cbei_2996 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 150017609 Common - urea amidolyase related protein Cbei_2756 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 150019658 Common - RNA methyltransferase, TrmA family Cbei_4850 206 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 150019059 Common flgG flagellar basal body rod protein FlgG Cbei_4247 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 150017574 Common - putative transcriptional regulator, MerR family Cbei_2721 40 COG0789 SoxR, Predicted transcriptional regulators Transcription 150018980 Common - integral membrane sensor signal transduction histidine kinase Cbei_4168 84 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015098 Common - dihydropteroate synthase Cbei_0206 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 150015027 Common - RNA polymerase factor sigma-70 Cbei_0135 109 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150017027 Common - Rubredoxin-type Fe(Cys)4 protein Cbei_2158 12 COG1592 COG1592, Rubrerythrin Energy production and conversion 150017420 Common - Aluminium resistance family protein Cbei_2562 29 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 150017991 Common - type III restriction protein, res subunit Cbei_3156 134 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 150017072 Common - membrane protein Cbei_2203 7 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 150017974 Common - GCN5-related N-acetyltransferase Cbei_3136 37 COG0456 RimI, Acetyltransferases General function prediction only 150017199 Common - putative cell wall binding repeat-containing protein Cbei_2337 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015587 Common - glycyl-radical enzyme activating protein family Cbei_0701 71 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150019796 Common - hypothetical protein Cbei_4988 3 None None None 150017849 Common - hydrogenase assembly chaperone hypC/hupF Cbei_3008 67 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 150016964 Common - putative acyl carrier protein Cbei_2095 7 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150015459 Nonpathogen - hypothetical protein Cbei_0570 1 None None None 150018744 Common - alpha/beta hydrolase fold Cbei_3932 155 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150018489 Common - two component transcriptional regulator, winged helix family Cbei_3669 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016960 Common - NMT1/THI5-like protein Cbei_2091 119 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150015020 Common - PilT protein domain protein Cbei_0128 45 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 150018341 Common - phosphoenolpyruvate synthase Cbei_3516 163 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 150017623 Common - domain of unknown function DUF1745 Cbei_2770 24 COG3287 COG3287, Uncharacterized conserved protein Function unknown 150017653 Nonpathogen - hypothetical protein Cbei_2801 9 None None None 150016625 Common - anthranilate phosphoribosyltransferase Cbei_1751 224 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 150017242 Common - D-xylose ABC transporter, periplasmic substrate-binding protein Cbei_2380 107 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 150017481 Nonpathogen - hypothetical protein Cbei_2625 1 None None None 150017505 Common - Ferric reductase domain protein transmembrane component, N-terminal domain Cbei_2649 7 COG2717 COG2717, Predicted membrane protein Function unknown 150017331 Common - small acid-soluble spore protein, alpha/beta type Cbei_2471 14 None None None 150018406 Common - putative cell wall binding repeat-containing protein Cbei_3582 5 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150017466 Common - aspartate alpha-decarboxylase Cbei_2608 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 150017924 Common - isochorismatase hydrolase Cbei_3085 74 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 150018245 Nonpathogen - hypothetical protein Cbei_3417 1 None None None 150016626 Common - Indole-3-glycerol-phosphate synthase Cbei_1752 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 150017998 Common - MATE efflux family protein Cbei_3164 137 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150019606 Common - transcriptional regulator, GntR family Cbei_4797 139 COG2188 PhnF, Transcriptional regulators Transcription 150018791 Common - binding-protein-dependent transport systems inner membrane component Cbei_3979 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 150017597 Nonpathogen - hypothetical protein Cbei_2744 1 None None None 150017409 Nonpathogen - hypothetical protein Cbei_2551 1 None None None 150016441 Common - GCN5-related N-acetyltransferase Cbei_1565 85 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150017190 Common - transcriptional regulator, LysR family Cbei_2328 178 COG0583 LysR, Transcriptional regulator Transcription 150016052 Common - fatty acid/phospholipid synthesis protein Cbei_1168 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 150016989 Common - hypothetical protein Cbei_2120 1 None None None 150015763 Common - ABC transporter, periplasmic-binding, putative Cbei_0877 23 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150018879 Common - Xanthine/uracil/vitamin C permease Cbei_4067 134 COG2252 COG2252, Permeases General function prediction only 150019296 Common - multi-sensor signal transduction histidine kinase Cbei_4485 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150019611 Common - heavy metal translocating P-type ATPase Cbei_4802 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150016416 Common - phosphoesterase, RecJ domain protein Cbei_1538 180 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 150017627 Common - putative cell wall binding repeat-containing protein Cbei_2774 13 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015308 Common - F0F1 ATP synthase subunit beta Cbei_0418 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 150016969 Common - Vinylacetyl-CoA Delta-isomerase Cbei_2100 49 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 150018213 Common - hypothetical protein Cbei_3385 1 None None None 150015601 Common - nitroreductase Cbei_0715 60 COG0778 NfnB, Nitroreductase Energy production and conversion 150019636 Common - Protein-glutamate O-methyltransferase Cbei_4827 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 150017919 Common - small acid-soluble spore protein, alpha/beta type Cbei_3080 10 None None None 150014922 Common - hypothetical protein Cbei_0030 1 None None None 150018200 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3372 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150017127 Common - hypothetical protein Cbei_2264 6 None None None 150018270 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3443 23 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150017403 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein Cbei_2545 233 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 150017694 Common - ABC transporter related Cbei_2844 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150016980 Common - protein tyrosine phosphatase Cbei_2111 109 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 150019030 Common - type II secretion system protein E Cbei_4218 182 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 150015168 Common - transcriptional regulator, MarR family Cbei_0278 24 COG1846 MarR, Transcriptional regulators Transcription 150019821 Nonpathogen - hypothetical protein Cbei_5013 1 None None None 150015126 Common - Alanine racemase Cbei_0234 129 COG1609 PurR, Transcriptional regulators Transcription 150016284 Common - hypothetical protein Cbei_1404 7 None None None 150019149 Common - thiamine pyrophosphate protein domain protein TPP-binding Cbei_4337 44 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 150015315 Common - cell shape determining protein, MreB/Mrl family Cbei_0425 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 150015153 Common - ABC transporter related Cbei_0262 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150016140 Common - precorrin-3B C17-methyltransferase Cbei_1257 139 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 150018107 Common - amino acid permease-associated region Cbei_3276 154 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150016584 Common - DNA repair protein RecN Cbei_1710 205 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 150018416 Common - putative transcriptional regulator, TetR family Cbei_3593 7 COG1309 AcrR, Transcriptional regulator Transcription 150019628 Common - response regulator receiver protein Cbei_4819 203 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016439 Common - hypothetical protein Cbei_1563 8 None None None 150015450 Common - NCAIR mutase (PurE)-related protein Cbei_0561 70 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 150018234 Common - RNA polymerase sigma-70 Cbei_3406 4 None None None 150015915 Common - hypothetical protein Cbei_1029 1 None None None 150016401 Common - CBS domain containing protein Cbei_1523 110 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 150016911 Common - Citrate transporter Cbei_2041 35 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 150019248 Common - phage integrase family protein Cbei_4437 206 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150017862 Nonpathogen - hypothetical protein Cbei_3021 1 COG5513 COG5513, Predicted secreted protein Function unknown 150017050 Common - iron-containing alcohol dehydrogenase Cbei_2181 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150018168 Common - hypothetical protein Cbei_3339 3 None None None 150015613 Common - aldehyde dehydrogenase Cbei_0727 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150015203 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_0313 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150016833 Common - short-chain dehydrogenase/reductase SDR Cbei_1961 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150018706 Common - Alcohol dehydrogenase GroES domain protein Cbei_3890 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150018382 Nonpathogen - hypothetical protein Cbei_3558 2 COG2378 COG2378, Predicted transcriptional regulator Transcription 150017813 Common - prolipoprotein diacylglyceryl transferase Cbei_2970 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150015578 Common - Radical SAM domain protein Cbei_0690 24 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 150018491 Common - methyl-accepting chemotaxis sensory transducer Cbei_3671 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015546 Common - Methyltransferase type 11 Cbei_0657 28 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150018445 Nonpathogen - hypothetical protein Cbei_3623 1 None None None 150016259 Nonpathogen - hypothetical protein Cbei_1377 1 None None None 150014910 Common - phosphatidylserine decarboxylase Cbei_0018 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 150018398 Common - hypothetical protein Cbei_3574 1 None None None 150015941 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Cbei_1055 207 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 150016543 Common - extracellular solute-binding protein, family 3 Cbei_1667 158 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150019261 Common - Monosaccharide-transporting ATPase Cbei_4450 98 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 150017229 Common - ribose 5-phosphate isomerase Cbei_2367 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 150017304 Common - YibE/F family protein Cbei_2444 29 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 150019256 Common - extracellular solute-binding protein, family 1 Cbei_4445 109 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150016929 Common - SEC-C motif domain protein Cbei_2059 3 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 150019266 Common sgaE L-ribulose-5-phosphate 4-epimerase Cbei_4455 134 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 150019389 Common - putative accessory gene regulator protein Cbei_4578 4 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150017369 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_2511 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150018907 Common - Dihydroxy-acid dehydratase Cbei_4095 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150016261 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_1380 28 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017362 Common - histidine kinase Cbei_2504 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015481 Common - VanW family protein Cbei_0592 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 150019251 Common - hypothetical protein Cbei_4440 14 None None None 150016923 Common - ApbE family lipoprotein Cbei_2053 134 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150019663 Common - protein of unknown function DUF199 Cbei_4855 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 150018835 Common - cell wall hydrolase/autolysin Cbei_4023 155 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150017846 Common - ROK family protein Cbei_3005 140 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150014933 Common - BFD domain protein (2Fe-2S)-binding domain protein Cbei_0041 5 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 150015334 Common - glutamine synthetase, catalytic region Cbei_0444 129 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 150016220 Common - nicotinate phosphoribosyltransferase Cbei_1338 118 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 150018755 Common - GCN5-related N-acetyltransferase Cbei_3943 20 COG0456 RimI, Acetyltransferases General function prediction only 150016408 Common ruvA Holliday junction DNA helicase motor protein Cbei_1530 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 150018368 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3544 50 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150015802 Nonpathogen - hypothetical protein Cbei_0916 1 None None None 150015505 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Cbei_0616 19 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150015949 Common - peptidase M56, BlaR1 Cbei_1063 10 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 150017488 Nonpathogen - hypothetical protein Cbei_2632 1 None None None 150016303 Common - prolipoprotein diacylglyceryl transferase Cbei_1423 69 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150018662 Nonpathogen - hypothetical protein Cbei_3845 1 None None None 150016859 Common - regulatory protein, LysR Cbei_1987 66 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 150018548 Nonpathogen - hypothetical protein Cbei_3729 2 COG5660 COG5660, Predicted integral membrane protein Function unknown 150015107 Common - 3-isopropylmalate dehydratase, small subunit Cbei_0215 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 150017535 Common - Redoxin domain protein Cbei_2680 115 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150017210 Nonpathogen - hypothetical protein Cbei_2348 1 None None None 150019022 Common - hypothetical protein Cbei_4210 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 150018904 Common - 3-dehydroquinate synthase Cbei_4092 88 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 150019222 Common - Orn/Lys/Arg decarboxylase, major region Cbei_4411 102 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 150015275 Common - Spore coat protein CotS Cbei_0385 5 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 150018348 Common - hypothetical protein Cbei_3523 33 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 150015626 Common - transcriptional regulator, TetR family Cbei_0740 53 COG1309 AcrR, Transcriptional regulator Transcription 150019285 Common - calcium-translocating P-type ATPase, PMCA-type Cbei_4474 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150017144 Common - oxidoreductase FAD/NAD(P)-binding domain protein Cbei_2281 140 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 150016314 Common - hydroxylamine reductase Cbei_1434 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150019230 Common - galactokinase Cbei_4419 97 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 150016838 Common - molybdate ABC transporter, inner membrane subunit Cbei_1966 238 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 150018841 Common - glycosyl transferase, family 39 Cbei_4029 42 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 150016955 Common - Trans-2-enoyl-CoA reductase (NAD(+)) Cbei_2086 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 150016253 Common - hypothetical protein Cbei_1371 1 None None None 150017427 Common - DNA mismatch repair protein Cbei_2569 208 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150016680 Common - secretion protein HlyD family protein Cbei_1807 112 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150018738 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_3924 3 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 150016926 Common - flavocytochrome c Cbei_2056 224 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150018305 Common - transcriptional regulator, XRE family Cbei_3479 54 COG1476 COG1476, Predicted transcriptional regulators Transcription 150019037 Common - DNA polymerase, beta domain protein region Cbei_4225 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 150016382 Common - protein of unknown function DUF124 Cbei_1504 76 COG2013 COG2013, Uncharacterized conserved protein Function unknown 150015337 Common - 5-keto-4-deoxyuronate isomerase Cbei_0447 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 150016455 Common - stage V sporulation protein D Cbei_1579 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150016340 Common - hypothetical protein Cbei_1460 11 COG5663 COG5663, Uncharacterized conserved protein Function unknown 150018000 Nonpathogen - hypothetical protein Cbei_3166 1 None None None 150017320 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Cbei_2460 201 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 150015668 Common - formate/nitrite transporter Cbei_0782 101 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 150015407 Common - transcriptional regulator, LysR family Cbei_0517 193 COG0583 LysR, Transcriptional regulator Transcription 150018561 Nonpathogen - hypothetical protein Cbei_3742 2 None None None 150018535 Common - Domain of unknown function DUF1835 Cbei_3716 8 None None None 150018437 Common - methionine aminopeptidase, type I Cbei_3615 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 150018007 Common - transcriptional regulator, TetR family Cbei_3173 17 COG1309 AcrR, Transcriptional regulator Transcription 150017267 Common - hypothetical protein Cbei_2407 2 None None None 150018462 Common - transposase IS116/IS110/IS902 family protein Cbei_3641 85 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150019122 Common - CheD Cbei_4310 86 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 150015689 Common - Lytic transglycosylase, catalytic Cbei_0803 165 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150019012 Common - phage replisome organizer, putative Cbei_4200 4 None None None 150018896 Common - mannonate dehydratase Cbei_4084 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 150016747 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cbei_1874 158 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150017876 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Cbei_3035 192 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150016147 Common - cobalamin-5-phosphate synthase CobS Cbei_1265 137 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 150015936 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_1050 181 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150017178 Common - precorrin-4 C11-methyltransferase Cbei_2316 203 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 150018681 Common - Alcohol dehydrogenase GroES domain protein Cbei_3864 213 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 150019555 Common - putative cell wall binding repeat-containing protein Cbei_4745 2 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019521 Common - Glutamine--scyllo-inositol transaminase Cbei_4711 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150017233 Nonpathogen - hypothetical protein Cbei_2371 2 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150019434 Common - integral membrane sensor signal transduction histidine kinase Cbei_4624 196 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150018173 Common - Helix-turn-helix, type 11 domain protein Cbei_3345 95 COG2378 COG2378, Predicted transcriptional regulator Transcription 150015213 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Cbei_0323 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150016981 Common - arsenical-resistance protein Cbei_2112 143 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 150015672 Common - hydroxylamine reductase Cbei_0786 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150019901 Common - hypothetical protein Cbei_5093 13 None None None 150015280 Common - protein of unknown function DUF1021 Cbei_0390 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 150018525 Common - LuxR family transcriptional regulator Cbei_3706 16 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 150015428 Nonpathogen - hypothetical protein Cbei_0538 1 None None None 150017132 Common - hypothetical protein Cbei_2269 35 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150015002 Common - Mg2+ transporter protein, CorA family protein Cbei_0110 66 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 150015757 Common - ammonium transporter Cbei_0871 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 150015057 Common rpsH 30S ribosomal protein S8 Cbei_0165 246 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 150016945 Common - NUDIX hydrolase Cbei_2075 118 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150016977 Common - regulatory protein, ArsR Cbei_2108 169 COG0640 ArsR, Predicted transcriptional regulators Transcription 150018781 Common - FAD linked oxidase domain protein Cbei_3969 45 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150017075 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cbei_2206 8 None None None 150019549 Common - Undecaprenyl-phosphate galactose phosphotransferase Cbei_4739 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150015054 Common rplX 50S ribosomal protein L24 Cbei_0162 209 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 150017553 Common - hypothetical protein Cbei_2699 6 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 150016797 Nonpathogen - hypothetical protein Cbei_1925 1 None None None 150019881 Common - hypothetical protein Cbei_5073 16 None None None 150015956 Common - malonyl CoA-acyl carrier protein transacylase Cbei_1070 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 150018356 Common - NADH:flavin oxidoreductase/NADH oxidase Cbei_3532 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150019084 Common - OmpA/MotB domain protein Cbei_4272 151 COG1360 MotB, Flagellar motor protein Cell motility and secretion 150018386 Common - transposase IS116/IS110/IS902 family protein Cbei_3562 64 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150017203 Nonpathogen - hypothetical protein Cbei_2341 1 None None None 150019380 Common - 3-deoxy-7-phosphoheptulonate synthase Cbei_4569 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150018677 Common - transcriptional regulator, MarR family Cbei_3860 8 COG1846 MarR, Transcriptional regulators Transcription 150015502 Common - Nitrogenase Cbei_0613 65 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150018952 Nonpathogen - hypothetical protein Cbei_4140 1 None None None 150015881 Common - Tetratricopeptide TPR_2 repeat protein Cbei_0995 44 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150015894 Common - hypothetical protein Cbei_1008 6 COG3233 COG3233, Predicted deacetylase General function prediction only 150015475 Nonpathogen - hypothetical protein Cbei_0586 1 None None None 150015484 Common - RNA polymerase factor sigma-54 Cbei_0595 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 150019174 Nonpathogen - hypothetical protein Cbei_4362 1 None None None 150019186 Nonpathogen - hypothetical protein Cbei_4375 1 None None None 150018501 Nonpathogen - hypothetical protein Cbei_3681 1 None None None 150015261 Common - protein of unknown function DUF1113 Cbei_0371 12 COG4905 COG4905, Predicted membrane protein Function unknown 150019515 Common - PTS system, alpha-glucoside-specific IIBC subunit Cbei_4705 51 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150017482 Common - Deoxyribonuclease V Cbei_2626 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 150019735 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cbei_4927 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150017769 Nonpathogen - transcriptional regulators, AcrR family Cbei_2924 1 None None None 150015906 Common - protein of unknown function UPF0118 Cbei_1020 106 COG0628 PerM, Predicted permease General function prediction only 150017446 Common - Collagen triple helix repeat Cbei_2588 6 None None None 150016227 Nonpathogen - hypothetical protein Cbei_1345 1 None None None 150016749 Common scpB segregation and condensation protein B Cbei_1876 156 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 150017224 Common - helix-turn-helix- domain containing protein, AraC type Cbei_2362 113 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150018214 Common - putative periplasmic ligand-binding sensor protein Cbei_3386 6 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 150016526 Common - phage tail tape measure protein, TP901 family Cbei_1650 58 COG5280 COG5280, Phage-related minor tail protein Function unknown 150015651 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Cbei_0765 218 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150018033 Common - phage replisome organizer, putative Cbei_3201 4 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150019085 Common - MotA/TolQ/ExbB proton channel Cbei_4273 85 COG1291 MotA, Flagellar motor component Cell motility and secretion 150015598 Common - phosphotransferase system PTS, sorbose-specific IIC subunit Cbei_0712 34 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150015780 Nonpathogen - hypothetical protein Cbei_0894 1 None None None 150018050 Nonpathogen - hypothetical protein Cbei_3218 2 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 150019417 Common - flagella-associated protein Cbei_4607 91 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 150017861 Common - carbon-monoxide dehydrogenase, catalytic subunit Cbei_3020 26 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150015152 Common - efflux transporter, RND family, MFP subunit Cbei_0261 159 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150018556 Common - NADPH-dependent FMN reductase Cbei_3737 44 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150016502 Common - protein of unknown function DUF1064 Cbei_1626 10 None None None 150016676 Nonpathogen - hypothetical protein Cbei_1803 1 None None None 150018012 Common - short-chain dehydrogenase/reductase SDR Cbei_3180 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150015766 Common - hypothetical protein Cbei_0880 7 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150016256 Nonpathogen - hypothetical protein Cbei_1374 3 None None None 150019774 Common - ABC-type sugar transport system periplasmic component-like protein Cbei_4966 66 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015345 Common - L-1,2-propanediol oxidoreductase Cbei_0455 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 150015924 Common - putative sulfonate/nitrate transport system substrate-binding protein Cbei_1038 39 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150016099 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cbei_1215 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 150015289 Common rho transcription termination factor Rho Cbei_0399 206 COG1158 Rho, Transcription termination factor Transcription 150019849 Common - putative RNA methylase Cbei_5041 29 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 150016647 Common - hydrogenase, Fe-only Cbei_1773 151 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150017092 Common - small acid-soluble spore protein, alpha/beta type Cbei_2225 12 None None None 150015673 Common - amino acid permease-associated region Cbei_0787 43 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150016150 Common - cobalamin biosynthesis protein CobD Cbei_1268 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 150016787 Common - hypothetical protein Cbei_1915 1 None None None 150018524 Common - hypothetical protein Cbei_3705 7 COG0456 RimI, Acetyltransferases General function prediction only 150015144 Common - Male sterility C-terminal domain Cbei_0252 50 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 150019681 Common - hypothetical protein Cbei_4873 1 None None None 150017555 Common - putative cell wall binding repeat-containing protein Cbei_2701 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150014954 Common - prolipoprotein diacylglyceryl transferase Cbei_0062 203 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150019542 Common - glycosyl transferase, group 1 Cbei_4732 90 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150019898 Common - Lysine exporter protein (LYSE/YGGA) Cbei_5090 27 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 150017140 Common - putative transcriptional regulator, Crp/Fnr family Cbei_2277 176 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150019426 Common - putative transcriptional regulator Cbei_4616 30 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 150019471 Common - helix-turn-helix- domain containing protein, AraC type Cbei_4661 117 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019441 Common - LicD family protein Cbei_4631 18 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 150018295 Common - flavodoxin Cbei_3468 37 COG0716 FldA, Flavodoxins Energy production and conversion 150019201 Nonpathogen - hypothetical protein Cbei_4390 1 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 150018797 Common - transposase Cbei_3985 6 None None None 150016640 Common - ABC transporter related Cbei_1766 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150018599 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3780 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150019038 Common - hypothetical protein Cbei_4226 1 None None None 150018917 Common - amine oxidase Cbei_4105 30 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 150016700 Common - hypothetical protein Cbei_1827 10 None None None 150018577 Common - putative CoA-substrate-specific enzyme activase Cbei_3758 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 150018241 Common - AraC protein, arabinose-binding/dimerisation Cbei_3413 97 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 150017983 Common - type IV pilus assembly PilZ Cbei_3148 2 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 150016399 Common - transcriptional regulator, TetR family Cbei_1521 12 COG1309 AcrR, Transcriptional regulator Transcription 150017217 Common - exodeoxyribonuclease III Xth Cbei_2355 198 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 150018485 Common - histidine kinase Cbei_3665 215 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150016391 Common - transcriptional regulator, GntR family Cbei_1513 115 COG1802 GntR, Transcriptional regulators Transcription 150015490 Common - hypothetical protein Cbei_0601 2 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 150017241 Common - response regulator receiver protein Cbei_2379 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150017476 Nonpathogen - hypothetical protein Cbei_2620 1 None None None 150019686 Common - single-strand binding protein Cbei_4878 211 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150017903 Common - protein of unknown function DUF156 Cbei_3063 89 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 150018881 Common - iron dependent repressor Cbei_4069 98 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 150018072 Nonpathogen - hypothetical protein Cbei_3241 2 None None None 150015427 Common - response regulator receiver protein Cbei_0537 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150017581 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_2728 216 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150016201 Common - Imidazoleglycerol-phosphate dehydratase Cbei_1319 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 150015139 Common - serine O-acetyltransferase Cbei_0247 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 150015646 Common - membrane spanning protein Cbei_0760 15 COG4720 COG4720, Predicted membrane protein Function unknown 150016278 Common - transposase IS3/IS911 family protein Cbei_1397 35 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 150016635 Common - Tetratricopeptide TPR_2 repeat protein Cbei_1761 13 None None None 150018276 Common - NUDIX hydrolase Cbei_3449 39 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150017711 Common - Epoxide hydrolase domain protein Cbei_2862 56 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150019595 Common - signal peptidase I Cbei_4786 164 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150018019 Nonpathogen - hypothetical protein Cbei_3187 1 None None None 150018161 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Cbei_3332 107 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 150017600 Common - hypothetical protein Cbei_2747 22 None None None 150016893 Common - hypothetical protein Cbei_2021 14 None None None 150015068 Common rpmJ 50S ribosomal protein L36 Cbei_0176 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 150017706 Common - Methyltransferase type 11 Cbei_2857 120 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 150018268 Common - transposase Cbei_3441 6 None None None 150014917 Common - gamma-glutamyl phosphate reductase Cbei_0025 202 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 150019877 Common - DNA replication protein DnaC Cbei_5069 14 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150018079 Common - hypothetical protein Cbei_3248 7 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150017489 Common - hypothetical protein Cbei_2633 5 None None None 150016107 Common - hypothetical protein Cbei_1223 11 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150016709 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase Cbei_1836 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 150017690 Common - Extradiol ring-cleavage dioxygenase, class III protein, subunit B Cbei_2840 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 150016032 Common - sun protein Cbei_1148 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 150016886 Nonpathogen - hypothetical protein Cbei_2014 1 COG2445 COG2445, Uncharacterized conserved protein Function unknown 150018327 Common - histidine kinase internal region Cbei_3502 101 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150016773 Common - Peptidoglycan glycosyltransferase Cbei_1900 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150015297 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Cbei_0407 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 150018570 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_3751 8 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150018822 Common - putative transcriptional regulator, AsnC family Cbei_4010 152 COG1522 Lrp, Transcriptional regulators Transcription 150016947 Common - amidase Cbei_2077 22 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 150016590 Common - hypothetical protein Cbei_1716 2 None None None 150016209 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Cbei_1327 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150017343 Common - two component transcriptional regulator, winged helix family Cbei_2484 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150015557 Nonpathogen - anti-sigma-factor antagonist Cbei_0668 11 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 150016211 Common - Sporulation protease LonB Cbei_1329 241 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 150015193 Common - hypothetical protein Cbei_0303 2 None None None 150017498 Common - MgtC/SapB transporter Cbei_2642 118 COG1285 SapB, Uncharacterized membrane protein Function unknown 150017995 Common - restriction modification system DNA specificity domain Cbei_3160 78 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 150018743 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_3931 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019091 Common - MaoC domain protein dehydratase Cbei_4279 83 COG2030 MaoC, Acyl dehydratase Lipid metabolism 150016465 Common - protein of unknown function DUF552 Cbei_1589 50 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 150015567 Common - ABC transporter related Cbei_0679 242 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150015259 Common - peptidase U62, modulator of DNA gyrase Cbei_0369 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 150016997 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Cbei_2128 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 150015415 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cbei_0525 48 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 150017654 Nonpathogen - hypothetical protein Cbei_2802 10 None None None 150017945 Nonpathogen - heat shock protein DnaJ domain protein Cbei_3106 1 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150015713 Common - coproporphyrinogen III oxidase Cbei_0827 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150018947 Common - pullulanase, type I Cbei_4135 161 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 150019868 Common - hypothetical protein Cbei_5060 2 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 150015934 Common - hypothetical protein Cbei_1048 10 None None None 150015909 Common - hypothetical protein Cbei_1023 1 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 150017285 Common - protein of unknown function DUF342 Cbei_2425 36 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 150019001 Common - adenylylsulfate reductase Cbei_4189 178 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150019167 Common - hypothetical protein Cbei_4355 6 None None None 150017618 Common - ABC transporter related Cbei_2765 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 150019878 Common - hypothetical protein Cbei_5070 1 None None None 150015710 Nonpathogen - hypothetical protein Cbei_0824 1 None None None 150018457 Common - cation diffusion facilitator family transporter Cbei_3635 210 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150019107 Common - carbon storage regulator, CsrA Cbei_4295 84 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 150018407 Common - alpha/beta hydrolase fold Cbei_3583 17 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150017410 Nonpathogen - hypothetical protein Cbei_2552 1 None None None 150018198 Common - hypothetical protein Cbei_3370 25 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 150019042 Common - penicillin-binding protein, 1A family Cbei_4230 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 150015815 Common - hypothetical protein Cbei_0929 1 None None None 150017547 Nonpathogen - hypothetical protein Cbei_2692 1 None None None 150016737 Common - hypothetical protein Cbei_1864 1 None None None 150016545 Nonpathogen - hypothetical protein Cbei_1669 1 None None None 150019008 Common - ferrous iron transport protein B Cbei_4196 155 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 150019187 Common - YD repeat protein Cbei_4376 78 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 150018884 Common - L-lactate dehydrogenase Cbei_4072 170 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 150019202 Common - hypothetical protein Cbei_4391 2 None None None 150019269 Common - histidine kinase internal region Cbei_4458 108 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150016451 Common - hypothetical protein Cbei_1575 136 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 150015845 Common - sugar isomerase (SIS) Cbei_0959 64 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 150016670 Common - aspartate-semialdehyde dehydrogenase Cbei_1797 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 150018853 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Cbei_4041 111 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 150019759 Common - DNA polymerase III subunits gamma and tau Cbei_4951 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 150017392 Common - FeoA family protein Cbei_2534 52 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 150017007 Common - periplasmic binding protein Cbei_2138 79 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150019364 Common - transcriptional regulator, DeoR family Cbei_4553 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 150018877 Common - protein of unknown function DUF336 Cbei_4065 52 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 150015977 Common - VanZ family protein Cbei_1092 13 COG5652 COG5652, Predicted integral membrane protein Function unknown 150015035 Common - ribosomal protein L7/L12 Cbei_0143 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 150019716 Common - glycogen/starch synthase, ADP-glucose type Cbei_4908 136 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 150019031 Common - peptidase A24A domain protein Cbei_4219 123 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150019228 Nonpathogen - hypothetical protein Cbei_4417 1 None None None 150019271 Common - Monosaccharide-transporting ATPase Cbei_4460 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 150018308 Common - peptide deformylase Cbei_3482 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 150016110 Common - GTP cyclohydrolase II Cbei_1226 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 150019833 Common - integral membrane sensor signal transduction histidine kinase Cbei_5025 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150015789 Common - prophage LambdaBa04, GP54 Cbei_0903 6 None None None 150015870 Common - Tetratricopeptide TPR_2 repeat protein Cbei_0984 22 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150016904 Common - 3-hydroxybutyryl-CoA dehydratase Cbei_2034 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150018849 Common - YdjC family protein Cbei_4037 52 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 150015889 Common pyrF orotidine 5'-phosphate decarboxylase Cbei_1003 73 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 150015066 Common - hypothetical protein Cbei_0174 4 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 150016111 Common ribH riboflavin synthase subunit beta Cbei_1227 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 150015357 Common - ribosomal-protein-alanine acetyltransferase Cbei_0467 210 COG0456 RimI, Acetyltransferases General function prediction only 150019608 Common - sugar isomerase (SIS) Cbei_4799 83 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 150019705 Common - elongation factor G Cbei_4897 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150019744 Common - aldehyde dehydrogenase Cbei_4936 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150015314 Common - Sporulation stage III, transcriptional regulator SpoIIID Cbei_0424 15 None None None 150018131 Common - hypothetical protein Cbei_3302 12 None None None 150015882 Common - mannose-6-phosphate isomerase, class I Cbei_0996 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 150018944 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cbei_4132 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150016765 Common - domain of unknown function DUF1745 Cbei_1892 27 COG3287 COG3287, Uncharacterized conserved protein Function unknown 150016254 Nonpathogen - hypothetical protein Cbei_1372 1 None None None 150017356 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cbei_2498 43 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 150015893 Common - stationary-phase survival protein SurE Cbei_1007 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 150018281 Common - peptidase C45, acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cbei_3454 13 COG4927 COG4927, Predicted choloylglycine hydrolase General function prediction only 150017492 Nonpathogen - hypothetical protein Cbei_2636 2 None None None 150015268 Common - hypothetical protein Cbei_0378 16 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150019467 Common - glucuronate isomerase Cbei_4657 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 150018784 Common - amino acid permease-associated region Cbei_3972 77 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 150016070 Common - DNA topoisomerase I Cbei_1186 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150018145 Common - NADH:flavin oxidoreductase/NADH oxidase Cbei_3316 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150015397 Common - ribonuclease, Rne/Rng family Cbei_0507 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 150019359 Common - thiamine pyrophosphate protein, central region Cbei_4548 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 150018174 Common - putative DNA alkylation repair enzyme Cbei_3346 36 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 150015091 Common - cell wall hydrolase, SleB Cbei_0199 18 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 150017504 Nonpathogen - hypothetical protein Cbei_2648 1 None None None 150016431 Common - hypothetical protein Cbei_1555 14 None None None 150018763 Common - protein of unknown function DUF161 Cbei_3951 75 COG1284 COG1284, Uncharacterized conserved protein Function unknown 150015404 Common - metal dependent phosphohydrolase Cbei_0514 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 150015173 Common - ABC transporter related Cbei_0283 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150015840 Common - sigma-54 factor, interaction domain-containing protein Cbei_0954 162 COG3933 COG3933, Transcriptional antiterminator Transcription 150019510 Nonpathogen - hypothetical protein Cbei_4700 1 None None None 150018895 Common - Mannitol dehydrogenase, C-terminal domain Cbei_4083 75 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 150019820 Common - PTS system, sucrose-specific IIBC subunit Cbei_5012 45 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150016345 Common - ferredoxin--NADP(+) reductase subunit alpha Cbei_1465 93 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150019142 Common - D-alanyl carrier protein Cbei_4330 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150017039 Nonpathogen - hypothetical protein Cbei_2170 1 None None None 150014990 Common - tRNA(Ile)-lysidine synthetase Cbei_0098 226 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 150016566 Common - Sporulation stage III, protein AA Cbei_1692 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 150018082 Nonpathogen - hypothetical protein Cbei_3251 1 None None None 150018138 Common - ABC transporter related Cbei_3309 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150015322 Common - sigma 54 modulation protein/ribosomal protein S30EA Cbei_0432 169 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 150015838 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Cbei_0952 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 150015877 Nonpathogen - hypothetical protein Cbei_0991 1 None None None 150019276 Common - Aldose 1-epimerase Cbei_4465 92 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 150017855 Common - hydroxylamine reductase Cbei_3014 76 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150015985 Common - hypothetical protein Cbei_1101 3 None None None 150018096 Common - amino acid-binding ACT domain protein Cbei_3265 22 COG3603 COG3603, Uncharacterized conserved protein Function unknown 150015364 Common - small acid-soluble spore protein, alpha/beta type Cbei_0474 13 None None None 150015576 Common - beta-lactamase domain protein Cbei_0688 206 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150015394 Common - hypothetical protein Cbei_0504 15 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 150016023 Common - hypothetical protein Cbei_1139 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 150017465 Nonpathogen - hypothetical protein Cbei_2607 1 None None None 150015183 Common - threonyl-tRNA synthetase Cbei_0293 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150019723 Common - sigma-54 factor, interaction domain-containing protein Cbei_4915 156 COG3933 COG3933, Transcriptional antiterminator Transcription 150019260 Common - ABC transporter related Cbei_4449 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150015844 Common - PTS system mannose/fructose/sorbose family IID component Cbei_0958 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150017527 Nonpathogen - hypothetical protein Cbei_2672 1 None None None 150017784 Common - short-chain dehydrogenase/reductase SDR Cbei_2940 225 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 150017157 Common - Chloramphenicol O-acetyltransferase Cbei_2295 22 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 150019588 Common - ABC transporter related Cbei_4779 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 150019246 Common - methyl-accepting chemotaxis sensory transducer Cbei_4435 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019673 Common - membrane protein containing C-terminal PDZ domain Cbei_4865 11 None None None 150016151 Common - L-threonine-O-3-phosphate decarboxylase Cbei_1269 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150018317 Common - major facilitator superfamily MFS_1 Cbei_3492 122 None None None 150017539 Common - metal dependent phosphohydrolase Cbei_2684 4 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150018257 Common - transcriptional regulator, HxlR family Cbei_3429 117 COG1733 COG1733, Predicted transcriptional regulators Transcription 150015528 Common - protein of unknown function DUF1232 Cbei_0639 11 COG3339 COG3339, Uncharacterized conserved protein Function unknown 150017799 Common - uncharacterized protein, ErfK family; contains peptidoglycan-binding domain Cbei_2956 1 None None None 150017103 Nonpathogen - hypothetical protein Cbei_2236 1 None None None 150014997 Common lysS lysyl-tRNA synthetase Cbei_0105 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150016135 Common - protein of unknown function DUF326 Cbei_1252 46 None None None 150016865 Common - TOBE domain protein Cbei_1993 71 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 150019405 Common dcd deoxycytidine triphosphate deaminase Cbei_4595 73 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 150016231 Nonpathogen - hypothetical protein Cbei_1349 1 None None None 150016191 Common - sodium:dicarboxylate symporter Cbei_1309 143 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 150018057 Nonpathogen - hypothetical protein Cbei_3225 1 None None None 150018450 Common - DNA binding domain, excisionase family Cbei_3628 8 None None None 150017438 Common - hypothetical protein Cbei_2580 6 COG3391 COG3391, Uncharacterized conserved protein Function unknown 150019867 Common - methyl-accepting chemotaxis sensory transducer Cbei_5059 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015311 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cbei_0421 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 150015827 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cbei_0941 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 150017887 Common - NADPH-dependent FMN reductase Cbei_3046 38 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150019460 Common - regulatory protein, LacI Cbei_4650 124 COG1609 PurR, Transcriptional regulators Transcription 150018262 Common - protein of unknown function DUF6, transmembrane Cbei_3435 79 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150015391 Common - peptidase M50 Cbei_0501 56 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 150016538 Common - hypothetical protein Cbei_1662 39 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 150019134 Common - DJ-1 family protein Cbei_4322 167 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 150019704 Common - hypothetical protein Cbei_4896 1 None None None 150015584 Common - transcriptional regulator, RpiR family Cbei_0698 32 COG1737 RpiR, Transcriptional regulators Transcription 150018956 Common - inner-membrane translocator Cbei_4144 135 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 150017096 Common - amidohydrolase Cbei_2229 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 150016956 Common - integral membrane sensor signal transduction histidine kinase Cbei_2087 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016697 Common - ATP-dependent DNA helicase RecQ Cbei_1824 240 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 150016335 Common - putative cell wall binding repeat-containing protein Cbei_1455 5 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150016792 Common - transcriptional regulator, RpiR family Cbei_1920 129 COG1737 RpiR, Transcriptional regulators Transcription 150015900 Common - L-lactate dehydrogenase Cbei_1014 169 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 150016604 Common - NUDIX hydrolase Cbei_1730 15 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 150018087 Nonpathogen - hypothetical protein Cbei_3256 1 None None None 150017100 Common - methyl-accepting chemotaxis sensory transducer Cbei_2233 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019571 Common - putative cell wall binding repeat-containing protein Cbei_4762 8 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019903 Common - Cobyrinic acid a,c-diamide synthase Cbei_5095 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150019198 Nonpathogen - hypothetical protein Cbei_4387 1 None None None 150016881 Common - putative transcriptional regulator, AsnC family Cbei_2009 53 COG1522 Lrp, Transcriptional regulators Transcription 150017688 Common - transcriptional regulator, MarR family Cbei_2838 3 COG1846 MarR, Transcriptional regulators Transcription 150015207 Common - Transaldolase Cbei_0317 149 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150018429 Common - Helix-turn-helix, type 11 domain protein Cbei_3607 30 COG2378 COG2378, Predicted transcriptional regulator Transcription 150017812 Common - Polyprenyl synthetase Cbei_2969 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 150018601 Common - putative transcriptional regulator, MerR family Cbei_3782 28 COG0789 SoxR, Predicted transcriptional regulators Transcription 150018800 Common - Abortive infection protein Cbei_3988 23 None None None 150016187 Common - lysophospholipase Cbei_1305 49 COG2267 PldB, Lysophospholipase Lipid metabolism 150016714 Common - Phosphomethylpyrimidine kinase type-1 Cbei_1841 27 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 150018984 Common - extracellular solute-binding protein, family 3 Cbei_4172 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150018422 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3600 52 COG0778 NfnB, Nitroreductase Energy production and conversion 150015832 Common - recombination and DNA strand exchange inhibitor protein Cbei_0946 201 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150015778 Common - hypothetical protein Cbei_0892 7 None None None 150016182 Common - hypothetical protein Cbei_1300 1 None None None 150016049 Common - acetate kinase Cbei_1165 162 COG0282 ackA, Acetate kinase Energy production and conversion 150018449 Common - hypothetical protein Cbei_3627 11 None None None 150015045 Common rplW 50S ribosomal protein L23 Cbei_0153 220 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 150015235 Common - pseudouridine synthase Cbei_0345 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150016616 Common - small GTP-binding protein Cbei_1742 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150016751 Common - hypothetical protein Cbei_1878 1 None None None 150019583 Common - putative aminopeptidase 2 Cbei_4774 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 150018540 Common - response regulator receiver protein Cbei_3721 17 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150019372 Common - transcriptional regulator, GntR family Cbei_4561 136 COG2188 PhnF, Transcriptional regulators Transcription 150016511 Common - phage-related terminase small subunit-like protein Cbei_1635 5 COG5484 COG5484, Uncharacterized conserved protein Function unknown 150017451 Common - hypothetical protein Cbei_2593 17 COG4089 COG4089, Predicted membrane protein Function unknown 150016937 Common - amidohydrolase Cbei_2067 173 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 150017733 Common - L-lactate transport Cbei_2885 104 COG1620 LldP, L-lactate permease Energy production and conversion 150015212 Common - acyl-CoA dehydrogenase domain protein Cbei_0322 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150018025 Nonpathogen - hypothetical protein Cbei_3193 1 None None None 150019350 Common - sigma-54 factor, interaction domain-containing protein Cbei_4539 157 COG3933 COG3933, Transcriptional antiterminator Transcription 150016016 Common - phosphate uptake regulator, PhoU Cbei_1132 200 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 150016080 Common - putative membrane-associated zinc metalloprotease Cbei_1196 220 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 150016104 Common - hypothetical protein Cbei_1220 3 COG2155 COG2155, Uncharacterized conserved protein Function unknown 150019379 Common - Prephenate dehydrogenase Cbei_4568 154 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 150017126 Nonpathogen - Lytic transglycosylase, catalytic Cbei_2261 2 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150017790 Common - UvrD/REP helicase Cbei_2947 127 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 150016024 Common - hypothetical protein Cbei_1140 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 150018598 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Cbei_3779 74 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150019320 Common glpK glycerol kinase Cbei_4509 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 150015037 Common - DNA-directed RNA polymerase subunit beta' Cbei_0145 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 150015412 Nonpathogen - hypothetical protein Cbei_0522 1 None None None 150017519 Common - glycoside hydrolase, family 4 Cbei_2664 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150016615 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Cbei_1741 196 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150018026 Common - hypothetical protein Cbei_3194 2 None None None 150015993 Common - beta-lactamase domain protein Cbei_1109 164 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 150017032 Nonpathogen - hypothetical protein Cbei_2163 1 None None None 150018547 Common - glycoside hydrolase, family 25 Cbei_3728 40 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150019342 Common - hypothetical protein Cbei_4531 10 None None None 150018810 Common - rRNA (guanine-N(1)-)-methyltransferase Cbei_3998 56 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150018229 Nonpathogen - hypothetical protein Cbei_3401 1 None None None 150016057 Common - signal recognition particle-docking protein FtsY Cbei_1173 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 150017745 Common - histidine kinase internal region Cbei_2898 105 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150016426 Common - protein of unknown function DUF975 Cbei_1550 14 COG5523 COG5523, Predicted integral membrane protein Function unknown 150019329 Common - arginine biosynthesis bifunctional protein ArgJ Cbei_4518 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 150014965 Common - glycosyl transferase, family 2 Cbei_0073 133 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150018065 Common - protein of unknown function DUF214 Cbei_3234 37 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 150016178 Nonpathogen - hypothetical protein Cbei_1296 1 None None None 150018442 Common - transcriptional regulator, HxlR family Cbei_3620 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 150016274 Common - hypothetical protein Cbei_1393 1 None None None 150015075 Common - ABC transporter related Cbei_0183 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150018049 Common - Chloramphenicol O-acetyltransferase Cbei_3217 20 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 150017231 Common - AAA ATPase Cbei_2369 32 COG3910 COG3910, Predicted ATPase General function prediction only 150015370 Common - CBS domain containing protein Cbei_0480 15 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 150018979 Common - ABC transporter related Cbei_4167 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150019032 Nonpathogen - hypothetical protein Cbei_4220 1 None None None 150015911 Common - hypothetical protein Cbei_1025 7 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 150017889 Common - ABC transporter related Cbei_3049 245 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150017425 Common aat leucyl/phenylalanyl-tRNA--protein transferase Cbei_2567 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 150019027 Common - type IV pilus assembly protein PilM Cbei_4215 73 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 150015166 Common - transcriptional regulator, MarR family Cbei_0276 10 COG1846 MarR, Transcriptional regulators Transcription 150017141 Common - hypothetical protein Cbei_2278 24 COG4309 COG4309, Uncharacterized conserved protein Function unknown 150017226 Common - Glycerol-1-phosphate dehydrogenase (NAD(P)(+)) Cbei_2364 68 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 150018714 Common - transcription activator, effector binding Cbei_3898 38 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150016658 Common - HIRAN Cbei_1785 3 None None None 150015052 Common rpsQ 30S ribosomal protein S17 Cbei_0160 223 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 150015574 Common - AMP-dependent synthetase and ligase Cbei_0686 217 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150017972 Common - aldo/keto reductase Cbei_3134 193 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 150016846 Common - Xanthine/uracil/vitamin C permease Cbei_1974 135 COG2252 COG2252, Permeases General function prediction only 150018490 Common - RNA-directed DNA polymerase (Reverse transcriptase) Cbei_3670 94 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 150017979 Nonpathogen - hypothetical protein Cbei_3141 1 None None None 150016860 Common - molybdopterin binding domain Cbei_1988 73 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 150016553 Common - putative transcriptional regulator, XRE family Cbei_1678 4 COG3655 COG3655, Predicted transcriptional regulator Transcription 150017643 Common - hypothetical protein Cbei_2791 2 None None None 150019800 Nonpathogen - hypothetical protein Cbei_4992 1 None None None 150019539 Common - polysaccharide biosynthesis protein Cbei_4729 98 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150016987 Common - integral membrane sensor signal transduction histidine kinase Cbei_2118 217 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150016720 Common - transcriptional regulator, BadM/Rrf2 family Cbei_1847 93 COG1959 COG1959, Predicted transcriptional regulator Transcription 150015040 Common - elongation factor G Cbei_0148 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150019218 Nonpathogen - hypothetical protein Cbei_4407 1 None None None 150016531 Common - hypothetical protein Cbei_1655 3 None None None 150015470 Common ddl D-alanine--D-alanine ligase Cbei_0581 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150017074 Common - putative transcriptional regulator, GntR family Cbei_2205 195 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150015730 Common - diacylglycerol kinase Cbei_0844 66 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 150015773 Nonpathogen - helix-turn-helix domain protein Cbei_0887 1 None None None 150015240 Common - methyl-accepting chemotaxis sensory transducer Cbei_0350 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019330 Common - acetylglutamate kinase Cbei_4519 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 150018259 Common - hypothetical protein Cbei_3432 3 None None None 150017416 Nonpathogen - hypothetical protein Cbei_2558 1 None None None 150017647 Common - hypothetical protein Cbei_2795 11 None None None 150016791 Common - protein of unknown function DUF871 Cbei_1919 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 150019451 Common - sigma-54 factor, interaction domain-containing protein Cbei_4641 164 COG3933 COG3933, Transcriptional antiterminator Transcription 150015171 Nonpathogen - hypothetical protein Cbei_0281 1 None None None 150016707 Common - histidine triad (HIT) protein Cbei_1834 45 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 150019670 Common - FHA domain containing protein Cbei_4862 65 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 150015954 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Cbei_1068 219 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150017432 Common - ABC transporter related Cbei_2574 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 150018902 Common - GCN5-related N-acetyltransferase Cbei_4090 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150017205 Common - putative transcriptional regulator, AsnC family Cbei_2343 159 COG1522 Lrp, Transcriptional regulators Transcription 150015004 Nonpathogen - hypothetical protein Cbei_0112 1 None None None 150017771 Common - putative cold-shock DNA-binding domain protein Cbei_2926 177 COG1278 CspC, Cold shock proteins Transcription 150019062 Common - type IV pilus assembly PilZ Cbei_4250 14 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 150019101 Common - flagellin domain protein Cbei_4289 121 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 150015219 Common groEL chaperonin GroEL Cbei_0329 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 150019459 Common - Xylose isomerase domain protein TIM barrel Cbei_4649 14 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 150019817 Common - PfkB domain protein Cbei_5009 195 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150018209 Common - hypothetical protein Cbei_3381 1 None None None 150018786 Common - aldo/keto reductase Cbei_3974 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 150019241 Common - multi-sensor signal transduction histidine kinase Cbei_4430 133 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150017897 Common - nitroreductase Cbei_3057 50 COG0778 NfnB, Nitroreductase Energy production and conversion 150016410 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cbei_1532 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 150017639 Common - methyl-accepting chemotaxis sensory transducer Cbei_2787 134 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018389 Common - two component transcriptional regulator, winged helix family Cbei_3565 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016362 Common - protein of unknown function DUF1432 Cbei_1482 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 150019496 Common - sigma-54 factor, interaction domain-containing protein Cbei_4686 161 COG3933 COG3933, Transcriptional antiterminator Transcription 150018982 Common - polar amino acid ABC transporter, inner membrane subunit Cbei_4170 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 150018730 Common - major facilitator superfamily MFS_1 Cbei_3916 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150019497 Common - phage infection protein, putative Cbei_4687 49 COG1511 COG1511, Predicted membrane protein Function unknown 150017756 Common - GCN5-related N-acetyltransferase Cbei_2911 16 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150016096 Common - peptidase S14, ClpP Cbei_1212 15 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150016059 Common - signal recognition particle protein Cbei_1175 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 150017351 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_2492 23 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150019254 Common - binding-protein-dependent transport systems inner membrane component Cbei_4443 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150017138 Common - hypothetical protein Cbei_2275 1 None None None 150019532 Common - cell wall/surface repeat protein Cbei_4722 136 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018047 Common - nitroreductase Cbei_3215 24 COG0778 NfnB, Nitroreductase Energy production and conversion 150015918 Common - RNA binding S1 domain protein Cbei_1032 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 150019020 Common - SNARE associated Golgi protein Cbei_4208 166 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 150019109 Common - flagellar hook-associated protein 3 Cbei_4297 107 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 150018378 Common - conserved hypothetical cytosolic protein Cbei_3554 21 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 150019231 Common - UDP-glucose 4-epimerase Cbei_4420 234 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 150018511 Common - protein of unknown function DUF214 Cbei_3692 10 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 150018774 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cbei_3962 151 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150016062 Common rimM 16S rRNA-processing protein Cbei_1178 98 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 150015628 Common - membrane protein Cbei_0742 19 None None None 150015682 Common - UspA domain protein Cbei_0796 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 150016263 Common - histidine kinase internal region Cbei_1382 108 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150015705 Common - ComEC/Rec2-related protein Cbei_0819 126 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 150018176 Common - desulfoferrodoxin Cbei_3348 23 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 150019171 Common - glycoside hydrolase, family 4 Cbei_4359 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150016473 Common - putative RNA methylase Cbei_1597 134 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 150018371 Common - protein of unknown function DUF89 Cbei_3547 40 COG1578 COG1578, Uncharacterized conserved protein Function unknown 150016317 Common - lipoprotein, putative Cbei_1437 9 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 150015548 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cbei_0659 167 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150016168 Common - uroporphyrin-III C-methyltransferase Cbei_1286 207 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 150019382 Common - Shikimate kinase Cbei_4571 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 150015274 Common - hypothetical protein Cbei_0384 1 None None None 150017307 Common - GCN5-related N-acetyltransferase Cbei_2447 34 COG2388 COG2388, Predicted acetyltransferase General function prediction only 150015533 Common - CBS domain containing protein Cbei_0644 100 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 150017445 Common - Collagen triple helix repeat Cbei_2587 5 None None None 150014901 Common - 3H domain protein Cbei_0009 16 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 150015852 Common - PTS system mannose/fructose/sorbose family IID component Cbei_0966 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 150017951 Common - hypothetical protein Cbei_3112 9 None None None 150018672 Common - protein of unknown function DUF214 Cbei_3855 21 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 150018739 Common - cyclase family protein Cbei_3925 91 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 150016847 Common - adenine deaminase Cbei_1975 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 150015873 Common - hypothetical protein Cbei_0987 22 None None None 150018121 Common - hypothetical protein Cbei_3292 153 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 150018992 Common - response regulator receiver modulated CheB methylesterase Cbei_4180 216 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 150017666 Common - phage replisome organizer, putative Cbei_2815 4 None None None 150016954 Common - dihydrouridine synthase, DuS Cbei_2085 163 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 150015541 Common - putative tryptophan transport protein Cbei_0652 8 None None None 150016323 Common - Alpha-glucosidase Cbei_1443 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 150015615 Common - aldehyde dehydrogenase Cbei_0729 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150019153 Common - hypothetical protein Cbei_4341 1 None None None 150015739 Common - RNA polymerase sigma factor RpoD Cbei_0853 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 150015206 Common - glycyl-radical enzyme activating protein family Cbei_0316 66 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150018158 Common - Thioredoxin domain Cbei_3329 164 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150017364 Nonpathogen - hypothetical protein Cbei_2506 2 None None None 150017918 Common - PAS/PAC sensor hybrid histidine kinase Cbei_3079 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019236 Common - carbonic anhydrase Cbei_4425 36 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 150014985 Common - YabP family protein Cbei_0093 13 None None None 150015662 Common - thioredoxin Cbei_0776 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150016266 Common - cell division protein FtsA Cbei_1385 147 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 150018958 Common - ABC transporter related Cbei_4146 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 150015824 Nonpathogen - hypothetical protein Cbei_0938 1 None None None 150015016 Common - thioredoxin reductase Cbei_0124 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150017271 Common - hypothetical protein Cbei_2411 6 None None None 150015130 Common - protein of unknown function DUF214 Cbei_0238 161 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 150018352 Common - Stress responsive alpha-beta barrel domain protein Cbei_3528 12 None None None 150015808 Common - hypothetical protein Cbei_0922 2 None None None 150018432 Common - Tn554-related, transposase C Cbei_3610 6 None None None 150018664 Common - transcription activator, effector binding Cbei_3847 61 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019274 Common - periplasmic binding protein/LacI transcriptional regulator Cbei_4463 84 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018527 Common - putative transporter Cbei_3708 85 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 150018166 Nonpathogen - hypothetical protein Cbei_3337 1 None None None 150017607 Common - acetyl-CoA carboxylase, biotin carboxylase Cbei_2754 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 150017521 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_2666 28 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150019280 Common - SCP-like extracellular Cbei_4469 73 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 150015418 Common - Alcohol dehydrogenase, zinc-binding domain protein Cbei_0528 106 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150017946 Common - transcriptional regulator, TetR family Cbei_3107 25 COG1309 AcrR, Transcriptional regulator Transcription 150015466 Common - cysteine synthase Cbei_0577 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150019500 Common - membrane spanning protein Cbei_4690 14 None None None 150017363 Common - putative galactoside ABC transporter Cbei_2505 65 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018843 Common - Radical SAM domain protein Cbei_4031 59 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150017068 Common - PTS system fructose subfamily IIA component Cbei_2199 53 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150018860 Common - microcompartments protein Cbei_4048 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150016515 Nonpathogen - hypothetical protein Cbei_1639 2 None None None 150019143 Common - membrane bound O-acyl transferase, MBOAT family protein Cbei_4331 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 150019481 Common - ABC transporter related Cbei_4671 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150018397 Common - transcriptional regulator, PadR-like family Cbei_3573 71 COG1695 COG1695, Predicted transcriptional regulators Transcription 150019694 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Cbei_4886 216 COG0313 COG0313, Predicted methyltransferases General function prediction only 150015339 Common - glycosyl hydrolase, family 88 Cbei_0449 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 150018575 Common - Cupin 2, conserved barrel domain protein Cbei_3756 8 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150015755 Common - short-chain dehydrogenase/reductase SDR Cbei_0869 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150018325 Common - binding-protein-dependent transport systems inner membrane component Cbei_3500 163 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150015434 Common - Alcohol dehydrogenase GroES domain protein Cbei_0544 216 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150018106 Common - small acid-soluble spore protein, alpha/beta type Cbei_3275 14 None None None 150016788 Common - protein of unknown function DUF541 Cbei_1916 85 COG2968 COG2968, Uncharacterized conserved protein Function unknown 150017513 Common - hypothetical protein Cbei_2658 2 None None None 150017592 Common ulaA ascorbate-specific PTS system enzyme IIC Cbei_2739 37 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 150019613 Common - PTS system, glucose subfamily, IIA subunit Cbei_4804 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 150016918 Common - integral membrane sensor signal transduction histidine kinase Cbei_2048 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150018642 Common - GCN5-related N-acetyltransferase Cbei_3824 66 COG0456 RimI, Acetyltransferases General function prediction only 150018404 Common - NADPH-dependent FMN reductase Cbei_3580 47 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150015922 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cbei_1036 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 150015088 Common - phosphoenolpyruvate-protein phosphotransferase Cbei_0196 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 150017873 Common - uncharacterized membrane protein Cbei_3032 9 None None None 150014906 Common - Recombination helicase AddA Cbei_0014 227 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 150016962 Common - ABC transporter related Cbei_2093 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150016665 Common - aminotransferase, class I and II Cbei_1792 242 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150015112 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cbei_0220 23 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 150018301 Common - polysaccharide deacetylase Cbei_3474 84 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150015177 Common - methyl-accepting chemotaxis sensory transducer Cbei_0287 171 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018188 Common - cyclic nucleotide-binding protein Cbei_3360 82 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150014897 Common - hypothetical protein Cbei_0005 12 None None None 150016623 Common - anthranilate synthase component I Cbei_1749 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 150018611 Common - molybdenum cofactor biosynthesis protein C Cbei_3792 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 150017081 Common - Integral membrane protein TerC Cbei_2212 92 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 150019709 Common - hypothetical protein Cbei_4901 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 150019478 Common - periplasmic solute binding protein Cbei_4668 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 150014925 Common - Peptidylprolyl isomerase Cbei_0033 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 150019826 Common - glycoside hydrolase, family 4 Cbei_5018 51 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150018237 Nonpathogen - hypothetical protein Cbei_3409 1 None None None 150016582 Common - ATP-NAD/AcoX kinase Cbei_1708 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 150019760 Common thyA thymidylate synthase Cbei_4952 140 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 150015817 Common - glycoside hydrolase, family 25 Cbei_0931 42 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150018117 Common - metal dependent phosphohydrolase Cbei_3288 89 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150019787 Nonpathogen - hypothetical protein Cbei_4979 1 None None None 150017913 Common - PAS/PAC sensor hybrid histidine kinase Cbei_3074 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017278 Common - Ppx/GppA phosphatase Cbei_2418 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 150017025 Common - 5'-3' exonuclease Cbei_2156 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 150019562 Common - glycosyl transferase, family 2 Cbei_4753 92 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150019162 Common - extracellular solute-binding protein, family 3 Cbei_4350 155 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150015117 Common - Transketolase, central region Cbei_0225 230 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 150015246 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Cbei_0356 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 150017747 Common - diguanylate cyclase Cbei_2900 180 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150014979 Common prsA peptidylprolyl isomerase Cbei_0087 161 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150016687 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_1814 198 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150015517 Common - Radical SAM domain protein Cbei_0628 93 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150015917 Common - carbonic anhydrase/acetyltransferase, isoleucine patch superfamily Cbei_1031 215 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 150018749 Common - GCN5-related N-acetyltransferase Cbei_3937 46 COG0456 RimI, Acetyltransferases General function prediction only 150019644 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_4835 59 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 150015947 Nonpathogen - hypothetical protein Cbei_1061 1 None None None 150017664 Common - Methyltransferase type 11 Cbei_2812 65 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150018218 Common - Baseplate J family protein Cbei_3390 22 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 150017192 Common - Methionine synthase, vitamin-B12 independent Cbei_2330 72 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 150017599 Common - VWA containing CoxE family protein Cbei_2746 26 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 150019294 Common - beta-lactamase domain protein Cbei_4483 85 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150016067 Common - hypothetical protein Cbei_1183 103 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 150016207 Common - hypothetical protein Cbei_1325 1 None None None 150017740 Common - binding-protein-dependent transport systems inner membrane component Cbei_2892 179 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150017752 Common - PTS system fructose subfamily IIA component Cbei_2905 33 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150019622 Common - response regulator receiver protein Cbei_4813 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150018038 Common thrS threonyl-tRNA synthetase Cbei_3206 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150015603 Common - putative transcriptional regulator, XRE family Cbei_0717 41 COG1396 HipB, Predicted transcriptional regulators Transcription 150015552 Common - protein of unknown function DUF161 Cbei_0663 11 COG2364 COG2364, Predicted membrane protein Function unknown 150015952 Common - hypothetical protein Cbei_1066 2 None None None 150015610 Common - transposase IS116/IS110/IS902 family protein Cbei_0724 85 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150017809 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_2966 38 COG0348 NapH, Polyferredoxin Energy production and conversion 150015369 Common - Exonuclease, RNase T and DNA polymerase III Cbei_0479 9 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 150019553 Common - protein of unknown function UPF0118 Cbei_4743 94 COG0628 PerM, Predicted permease General function prediction only 150017935 Common - ABC transporter related Cbei_3096 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 150019044 Common - Nucleoside-diphosphate kinase Cbei_4232 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 150017016 Common - sigma54 specific transcriptional regulator, Fis family Cbei_2147 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150019050 Common - diguanylate cyclase Cbei_4238 10 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150016453 Common - hypothetical protein Cbei_1577 1 None None None 150017408 Common - pentapeptide repeat protein Cbei_2550 34 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150019339 Common - major facilitator superfamily MFS_1 Cbei_4528 150 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 150019633 Common - response regulator receiver protein Cbei_4824 222 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 150017052 Common - putative oxidoreductase Cbei_2183 190 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 150016407 Common - hypothetical protein Cbei_1529 1 None None None 150018988 Common - branched-chain amino acid transport Cbei_4176 8 COG4392 COG4392, Predicted membrane protein Function unknown 150015606 Common - hypothetical protein Cbei_0720 9 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 150018974 Common - putative transcriptional regulator, MerR family Cbei_4162 127 COG0789 SoxR, Predicted transcriptional regulators Transcription 150018724 Common - transcriptional regulator, RpiR family Cbei_3910 64 COG1737 RpiR, Transcriptional regulators Transcription 150015477 Common - ABC transporter related Cbei_0588 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150018875 Common - ethanolamine utilization protein, EutP Cbei_4063 19 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 150019842 Common - ammonium transporter Cbei_5034 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 150015451 Common - NADH:flavin oxidoreductase/NADH oxidase Cbei_0562 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 150019118 Common - CheC, inhibitor of MCP methylation Cbei_4306 47 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 150019312 Common - helix-turn-helix- domain containing protein, AraC type Cbei_4501 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019659 Common - pyruvate kinase Cbei_4851 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 150018924 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Cbei_4112 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150018411 Nonpathogen - hypothetical protein Cbei_3588 1 None None None 150019507 Common - Zn-finger containing protein Cbei_4697 4 None None None 150018625 Common - AAA ATPase, central domain protein Cbei_3806 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 150017377 Common - hypothetical protein Cbei_2519 1 None None None 150017327 Common - fructose-1,6-bisphosphatase Cbei_2467 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 150015198 Common - Patatin Cbei_0308 56 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 150017047 Nonpathogen - hypothetical protein Cbei_2178 1 None None None 150018961 Common - aminotransferase, class I and II Cbei_4149 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150015768 Common - hypothetical protein Cbei_0882 14 None None None 150018191 Common - MgtE intracellular region Cbei_3363 176 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 150018220 Nonpathogen - hypothetical protein Cbei_3392 2 None None None 150017882 Common - Endo-1,4-beta-xylanase Cbei_3041 8 None None None 150016600 Common - uncharacterized membrane protein Cbei_1726 11 COG5542 COG5542, Predicted integral membrane protein Function unknown 150015105 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Cbei_0213 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150016967 Common - acyl-CoA reductase Cbei_2098 20 None None None 150018650 Common - 3-oxoacid CoA-transferase, A subunit Cbei_3833 100 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 150019419 Common - butyrate kinase Cbei_4609 129 COG3426 COG3426, Butyrate kinase Energy production and conversion 150016483 Nonpathogen - hypothetical protein Cbei_1607 1 None None None 150018627 Common - hypothetical protein Cbei_3808 4 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 150016805 Common - glucose-inhibited division protein A Cbei_1933 9 COG2081 COG2081, Predicted flavoproteins General function prediction only 150017844 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3003 67 COG0348 NapH, Polyferredoxin Energy production and conversion 150017439 Nonpathogen - hypothetical protein Cbei_2581 1 None None None 150015525 Common - ABC transporter related Cbei_0636 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 150018361 Common - hypothetical protein Cbei_3537 2 None None None 150015123 Common - binding-protein-dependent transport systems inner membrane component Cbei_0231 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 150016571 Common - Sporulation stage III, protein AF Cbei_1697 1 None None None 150016229 Nonpathogen - hypothetical protein Cbei_1347 1 None None None 150019666 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Cbei_4858 203 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 150018243 Common - GCN5-related N-acetyltransferase Cbei_3415 84 COG2153 ElaA, Predicted acyltransferase General function prediction only 150015694 Common - integral membrane sensor signal transduction histidine kinase Cbei_0808 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150019888 Common - Sporulation protease LonC Cbei_5080 242 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 150017629 Common - nitrite and sulphite reductase 4Fe-4S region Cbei_2776 161 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 150016281 Common - Vitamin B12 dependent methionine synthase, activation region Cbei_1401 9 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 150016196 Common - protein of unknown function DUF1275 Cbei_1314 14 COG3619 COG3619, Predicted membrane protein Function unknown 150016829 Common - thioesterase superfamily protein Cbei_1957 78 COG0824 FcbC, Predicted thioesterase General function prediction only 150016349 Common - hypothetical protein Cbei_1469 1 None None None 150015080 Common - N-acetylmuramoyl-L-alanine amidase CwlD Cbei_0188 144 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150016222 Common - phage integrase family protein Cbei_1340 117 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150015202 Common - FAD linked oxidase domain protein Cbei_0312 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150014994 Common - pantothenate kinase Cbei_0102 135 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 150019578 Nonpathogen - hypothetical protein Cbei_4769 1 None None None 150017187 Common - Rubrerythrin Cbei_2325 26 COG1592 COG1592, Rubrerythrin Energy production and conversion 150015593 Common - major facilitator superfamily MFS_1 Cbei_0707 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150015492 Common secG preprotein translocase subunit SecG Cbei_0603 4 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 150016087 Common - ribosome-binding factor A Cbei_1203 176 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 150019123 Common - putative CheW protein Cbei_4311 124 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150017387 Common - protein of unknown function UPF0126 Cbei_2529 133 COG2860 COG2860, Predicted membrane protein Function unknown 150015722 Common - MiaB-like tRNA modifying enzyme Cbei_0836 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150016856 Common - Xanthine dehydrogenase Cbei_1984 114 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 150016803 Nonpathogen - hypothetical protein Cbei_1931 2 None None None 150018467 Common - transcriptional regulator, TetR family Cbei_3646 19 COG1309 AcrR, Transcriptional regulator Transcription 150016651 Common - metallophosphoesterase Cbei_1777 90 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150015796 Common - uncharacterized phage protein Cbei_0910 2 None None None 150017373 Common - multi-sensor hybrid histidine kinase Cbei_2515 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150017901 Common - hypothetical protein Cbei_3061 5 None None None 150015444 Common - signal transduction histidine kinase, LytS Cbei_0555 104 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150016810 Common - ABC transporter related Cbei_1938 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150018005 Common - Accessory gene regulator B Cbei_3171 5 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 150015161 Common - transcriptional regulator, TetR family Cbei_0271 26 COG1309 AcrR, Transcriptional regulator Transcription 150017042 Common - Septum formation topological specificity factor MinE Cbei_2173 13 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 150017098 Common - Enoyl-CoA hydratase/isomerase Cbei_2231 127 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150019840 Common - metal dependent phosphohydrolase Cbei_5032 38 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 150017258 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Cbei_2398 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150016276 Common - transcriptional regulator, MarR family Cbei_1395 33 COG1846 MarR, Transcriptional regulators Transcription 150019726 Common - methyl-accepting chemotaxis sensory transducer Cbei_4918 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150015635 Common - transcriptional regulator, RpiR family Cbei_0749 100 COG1737 RpiR, Transcriptional regulators Transcription 150018802 Common - transcription activator, effector binding Cbei_3990 99 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019838 Nonpathogen - hypothetical protein Cbei_5030 1 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 150015401 Common obgE GTPase ObgE Cbei_0511 249 COG0536 Obg, Predicted GTPase General function prediction only 150018083 Common - protein of unknown function DUF161 Cbei_3252 45 COG1284 COG1284, Uncharacterized conserved protein Function unknown 150019490 Common - extracellular solute-binding protein, family 1 Cbei_4680 94 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015967 Common - ABC transporter related Cbei_1081 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 150016030 Common fmt methionyl-tRNA formyltransferase Cbei_1146 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 150015447 Common - aldo/keto reductase Cbei_0558 185 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 150016311 Common - seryl-tRNA synthetase Cbei_1431 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 150015244 Common - hypothetical protein Cbei_0354 1 None None None 150016633 Common - phosphoglycerate mutase 1 family Cbei_1759 163 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 150015732 Common recO DNA repair protein RecO Cbei_0846 78 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 150016384 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cbei_1506 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 150015191 Common - biotin synthase Cbei_0301 182 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 150017287 Common - xanthine phosphoribosyltransferase Cbei_2427 71 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 150017483 Common - hypothetical protein Cbei_2627 2 None None None 150017989 Nonpathogen - hypothetical protein Cbei_3154 5 None None None 150018666 Common - two component transcriptional regulator, winged helix family Cbei_3849 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150016689 Common - cobalamin synthesis protein, P47K Cbei_1816 125 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 150019080 Common fliF flagellar MS-ring protein Cbei_4268 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 150019702 Common - competence damage-inducible protein A Cbei_4894 213 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 150018937 Common - sugar (Glycoside-Pentoside-Hexuronide) transporter Cbei_4125 86 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150015070 Common - 30S ribosomal protein S11 Cbei_0178 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 150015858 Common - Non-specific serine/threonine protein kinase Cbei_0972 142 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150016445 Common - translation initiation factor IF-3 Cbei_1569 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 150017251 Common - L-fucose isomerase related protein Cbei_2389 13 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 150015175 Common - glycogen/starch/alpha-glucan phosphorylase Cbei_0285 141 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 150016725 Common - SUF system FeS assembly protein, NifU family Cbei_1852 174 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 150016481 Common - Resolvase, N-terminal domain Cbei_1605 136 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 150019014 Common - Abortive infection protein Cbei_4202 47 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 150018991 Common - Auxin Efflux Carrier Cbei_4179 43 COG0679 COG0679, Predicted permeases General function prediction only 150018741 Common - GCN5-related N-acetyltransferase Cbei_3929 105 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 150018857 Common - aldehyde dehydrogenase Cbei_4045 178 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150016884 Common - Homocitrate synthase Cbei_2012 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150018196 Common - Cupin 2, conserved barrel domain protein Cbei_3368 33 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150018592 Common - sucrose-6-phosphate hydrolase Cbei_3773 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 150017943 Common - transcriptional repressor, CopY family Cbei_3104 39 COG3682 COG3682, Predicted transcriptional regulator Transcription 150016318 Common - hypothetical protein Cbei_1438 2 None None None 150015565 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_0677 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150016649 Common - phosphate transporter Cbei_1775 169 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 150019182 Common - Deoxyribonuclease V Cbei_4370 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 150019160 Common - transcriptional regulator, PucR family Cbei_4348 28 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 150017797 Common - Cupin 2, conserved barrel domain protein Cbei_2954 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 150017150 Nonpathogen - hypothetical protein Cbei_2288 1 None None None 150015413 Common - RNA methyltransferase, TrmA family Cbei_0523 202 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 150017341 Nonpathogen - hypothetical protein Cbei_2482 1 None None None 150017004 Common - Peroxiredoxin Cbei_2135 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150015257 Common - Endothelin-converting enzyme 1 Cbei_0367 64 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 150015523 Common smpB SsrA-binding protein Cbei_0634 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 150016082 Common - hypothetical protein Cbei_1198 177 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 150017980 Common - D-galactose-binding periplasmic protein precursor Cbei_3142 55 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015979 Nonpathogen - hypothetical protein Cbei_1095 1 None None None 150018850 Common - hypothetical protein Cbei_4038 2 None None None 150017114 Common - two component transcriptional regulator, winged helix family Cbei_2249 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150019137 Common - glycosyl transferase, family 2 Cbei_4325 116 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150016916 Common - transposase Cbei_2046 6 None None None 150015884 Common - 6-phosphofructokinase Cbei_0998 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 150017735 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Cbei_2887 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150015256 Nonpathogen - hypothetical protein Cbei_0366 1 None None None 150017441 Common - hypothetical protein Cbei_2583 2 None None None 150019204 Nonpathogen - hypothetical protein Cbei_4393 1 None None None 150018549 Nonpathogen - hypothetical protein Cbei_3730 1 None None None 150019391 Common - two component transcriptional regulator, LytTR family Cbei_4580 54 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150018499 Common - Integrase, catalytic region Cbei_3679 130 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 150019639 Common - OmpA/MotB domain protein Cbei_4830 153 COG1360 MotB, Flagellar motor protein Cell motility and secretion 150017898 Common - Pirin domain protein Cbei_3058 141 COG1741 COG1741, Pirin-related protein General function prediction only 150018031 Common - transcriptional regulator, AbrB family Cbei_3199 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 150018430 Common - phage integrase family protein Cbei_3608 160 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150016008 Common - protein of unknown function DUF152 Cbei_1124 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 150019558 Common - Methyltransferase type 12 Cbei_4749 8 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 150017094 Common - transcriptional regulator, TrmB Cbei_2227 37 COG1378 COG1378, Predicted transcriptional regulators Transcription 150016372 Common - cell wall hydrolase/autolysin Cbei_1493 19 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150019064 Common flhF flagellar biosynthesis regulator FlhF Cbei_4252 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 150015155 Nonpathogen - hypothetical protein Cbei_0264 1 None None None 150016942 Common - extracellular solute-binding protein, family 3 Cbei_2072 141 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 150017222 Common - Alpha-N-arabinofuranosidase Cbei_2360 31 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 150017630 Common - beta-lactamase domain protein Cbei_2777 62 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150015312 Common - Sporulation stage II, protein D firmicutes Cbei_0422 47 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 150019282 Nonpathogen - hypothetical protein Cbei_4471 1 None None None 150016702 Common - Phosphoglycerate mutase Cbei_1829 5 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150015724 Common rpsU 30S ribosomal protein S21 Cbei_0838 74 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 150016500 Common - hypothetical protein Cbei_1624 1 None None None 150018476 Common - hypothetical protein Cbei_3655 5 None None None 150014950 Common - primase/topoisomerase like protein Cbei_0058 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 150017494 Common - pentapeptide repeat protein Cbei_2638 37 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150019586 Common - cation diffusion facilitator family transporter Cbei_4777 214 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 150016214 Nonpathogen - hypothetical protein Cbei_1332 1 COG4371 COG4371, Predicted membrane protein Function unknown 150016354 Common - branched-chain amino acid transport system II carrier protein Cbei_1474 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 150016494 Nonpathogen - hypothetical protein Cbei_1618 1 None None None 150017147 Common - hydroxylamine reductase Cbei_2284 76 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150017499 Common - Non-specific serine/threonine protein kinase Cbei_2643 151 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150019737 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cbei_4929 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 150018469 Common - Isoprenylcysteine carboxyl methyltransferase Cbei_3648 39 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 150018508 Nonpathogen - hypothetical protein Cbei_3688 1 None None None 150017515 Common - protein of unknown function DUF871 Cbei_2660 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 150019730 Common - hypothetical protein Cbei_4922 5 None None None 150017248 Common - putative transaldolase Cbei_2386 171 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150016146 Common - hypothetical protein Cbei_1264 26 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 150018212 Nonpathogen - hypothetical protein Cbei_3384 1 None None None 150018558 Common - metallophosphoesterase Cbei_3739 19 None None None 150016297 Common - Appr-1-p processing domain protein Cbei_1417 100 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 150017139 Common - hydroxylamine reductase Cbei_2276 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 150019098 Common - putative transposase Cbei_4286 16 None None None 150016102 Common - Stage V sporulation protein S Cbei_1218 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 150017767 Common - secretion protein HlyD Cbei_2922 124 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150019176 Nonpathogen - hypothetical protein Cbei_4364 1 None None None 150014977 Common - peptidyl-tRNA hydrolase Cbei_0085 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 150018685 Common - glycoside hydrolase, family 3 domain protein Cbei_3868 86 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150017298 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Cbei_2438 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150016508 Common - DNA methylase N-4/N-6 domain protein Cbei_1632 92 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 150017463 Nonpathogen - hypothetical protein Cbei_2605 1 None None None 150016090 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Cbei_1206 211 COG0196 RibF, FAD synthase Coenzyme metabolism 150019846 Common - protein of unknown function DUF81 Cbei_5038 121 COG0730 COG0730, Predicted permeases General function prediction only 150019905 Common gidB glucose-inhibited division protein B Cbei_5097 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 150016768 Common - protein of unknown function DUF477 Cbei_1895 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 150015287 Common - hypothetical protein Cbei_0397 1 None None None 150019891 Common - hypothetical protein Cbei_5083 5 None None None 150018392 Common - hypothetical protein Cbei_3568 1 None None None 150018040 Common - hypothetical protein Cbei_3208 25 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150016551 Common - beta-lactamase domain protein Cbei_1676 123 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 150018248 Common - Protein of unknown function DUF1847 Cbei_3420 16 COG4887 COG4887, Uncharacterized metal-binding protein conserved in archaea General function prediction only 150016462 Common - protein of unknown function DUF1290 Cbei_1586 23 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 150016753 Common - hypothetical protein Cbei_1880 17 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 150017766 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_2921 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150016240 Nonpathogen - helix-turn-helix domain protein Cbei_1358 1 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 150018719 Common - AraC-type transcriptional regulator domain protein Cbei_3903 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019772 Common - extracellular solute-binding protein, family 1 Cbei_4964 76 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017529 Common - ribosomal protein S21 Cbei_2674 88 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 150017546 Common - homocysteine S-methyltransferase Cbei_2691 31 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 150016730 Common - pentapeptide repeat protein Cbei_1857 62 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150017478 Common - Methyltransferase type 11 Cbei_2622 23 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150016072 Common rpsB 30S ribosomal protein S2 Cbei_1188 246 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 150018311 Common - transcriptional regulator, HxlR family Cbei_3485 145 COG1733 COG1733, Predicted transcriptional regulators Transcription 150018252 Common - Phosphoglycerate mutase Cbei_3424 193 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150016393 Common - protein of unknown function DUF255 Cbei_1515 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 150019483 Common - lipolytic protein, G-D-S-L family Cbei_4673 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150018915 Common - two component transcriptional regulator, winged helix family Cbei_4103 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150017419 Common - LexA repressor Cbei_2561 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150017472 Common - hypothetical protein Cbei_2616 1 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150016069 Common - DNA protecting protein DprA Cbei_1185 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 150017348 Common - protein of unknown function DUF523 Cbei_2489 75 COG1683 COG1683, Uncharacterized conserved protein Function unknown 150019443 Common - beta-lactamase domain protein Cbei_4633 46 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 150017750 Common - PTS system fructose subfamily IIA component Cbei_2903 97 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 150015904 Common - peptidase M50 Cbei_1018 93 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 150014957 Common - ferredoxin Cbei_0065 28 COG1141 Fer, Ferredoxin Energy production and conversion 150016820 Nonpathogen - hypothetical protein Cbei_1948 1 None None None 150014903 Common - protein of unknown function DUF1667 Cbei_0011 1 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 150017532 Common - hypothetical protein Cbei_2677 10 None None None 150015429 Common - hypothetical protein Cbei_0539 2 None None None 150018487 Nonpathogen - hypothetical protein Cbei_3667 1 None None None 150017314 Common - electron transport complex, RnfABCDGE type, B subunit Cbei_2454 93 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 150017676 Common - beta and gamma crystallin Cbei_2825 16 None None None 150018070 Common - hypothetical protein Cbei_3239 20 None None None 150015077 Common truA tRNA pseudouridine synthase A Cbei_0185 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 150019812 Common - GntR domain protein Cbei_5004 128 COG2186 FadR, Transcriptional regulators Transcription 150015776 Nonpathogen - hypothetical protein Cbei_0890 1 None None None 150018255 Common - GCN5-related N-acetyltransferase Cbei_3427 88 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150017537 Nonpathogen - hypothetical protein Cbei_2682 1 None None None 150018055 Nonpathogen - hypothetical protein Cbei_3223 1 None None None 150017704 Common - hypothetical protein Cbei_2855 13 COG4997 COG4997, Uncharacterized conserved protein Function unknown 150017954 Common - hypothetical protein Cbei_3115 7 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 150016935 Common - transcriptional regulator, TetR family Cbei_2065 110 COG1309 AcrR, Transcriptional regulator Transcription 150018753 Nonpathogen - hypothetical protein Cbei_3941 1 None None None 150017633 Common - Cof-like hydrolase Cbei_2780 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150016471 Common - pseudouridine synthase, RluA family Cbei_1595 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150015420 Common - sugar isomerase (SIS) Cbei_0530 52 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 150017684 Common - transcriptional antiterminator, BglG Cbei_2834 29 COG3711 BglG, Transcriptional antiterminator Transcription 150018972 Common - heat shock protein 90 Cbei_4160 148 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 150018286 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3459 17 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150017101 Common - bifunctional deaminase-reductase domain protein Cbei_2234 80 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 150017895 Common - ApbE family lipoprotein Cbei_3055 133 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150016189 Common - helix-turn-helix- domain containing protein, AraC type Cbei_1307 96 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150019344 Common - PTS system, glucose subfamily, IIA subunit Cbei_4533 61 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 150016863 Common - MOSC domain containing protein Cbei_1991 45 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 150019679 Common - Transketolase domain protein Cbei_4871 223 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 150015383 Common - rod shape-determining protein MreD Cbei_0493 4 None None None 150016949 Nonpathogen - hypothetical protein Cbei_2080 1 None None None 150018318 Common - putative transcriptional regulator, MerR family Cbei_3493 3 COG0789 SoxR, Predicted transcriptional regulators Transcription 150017583 Common - thiamine pyrophosphate protein, central region Cbei_2730 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150018951 Common - metal dependent phosphohydrolase Cbei_4139 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150019374 Common - transcriptional regulator, GntR family Cbei_4563 125 COG2188 PhnF, Transcriptional regulators Transcription 150016618 Common - protein of unknown function DUF606 Cbei_1744 3 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 150018264 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_3437 19 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150018077 Common - Methyltransferase type 11 Cbei_3246 131 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150015306 Common - F0F1 ATP synthase subunit alpha Cbei_0416 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 150015006 Common - protein of unknown function DUF970 Cbei_0114 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 150018670 Common - protein of unknown function DUF214 Cbei_3853 18 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 150018837 Common - hypothetical protein Cbei_4025 32 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 150015209 Common - hypothetical protein Cbei_0319 3 None None None 150016712 Common - Altronate dehydratase Cbei_1839 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 150015093 Common - YbbR family protein Cbei_0201 25 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 150015926 Common - ABC transporter related Cbei_1040 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 150016602 Nonpathogen - hypothetical protein Cbei_1728 2 None None None 150018206 Common - hypothetical protein Cbei_3378 2 COG5658 COG5658, Predicted integral membrane protein Function unknown 150017686 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_2836 19 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 150017833 Common - NADH dehydrogenase (quinone) Cbei_2992 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 150018028 Nonpathogen - hypothetical protein Cbei_3196 1 None None None 150016193 Common - 6-phosphogluconate dehydrogenase, NAD-binding Cbei_1311 183 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 150018374 Nonpathogen - hypothetical protein Cbei_3550 2 None None None 150016247 Nonpathogen - hypothetical protein Cbei_1365 1 None None None 150018694 Common - extracellular solute-binding protein, family 1 Cbei_3878 16 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150014963 Common - anaerobic ribonucleoside-triphosphate reductase activating protein Cbei_0071 68 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 150017457 Common - cysteine desulfurase family protein Cbei_2599 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150018494 Common - hypothetical protein Cbei_3674 3 None None None 150018872 Common - glycyl-radical enzyme activating protein family Cbei_4060 84 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 150017868 Common - transcriptional regulator, PadR-like family Cbei_3027 27 COG1695 COG1695, Predicted transcriptional regulators Transcription 150016438 Common - threonine dehydratase Cbei_1562 229 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 150017450 Common - hypothetical protein Cbei_2592 9 None None None 150016077 Common - phosphatidate cytidylyltransferase Cbei_1193 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 150018888 Common - ribokinase Cbei_4076 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150018710 Common - GCN5-related N-acetyltransferase Cbei_3894 151 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150018239 Common - helix-turn-helix- domain containing protein, AraC type Cbei_3411 143 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150015545 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Cbei_0656 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 150016184 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_1302 30 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150015124 Common - binding-protein-dependent transport systems inner membrane component Cbei_0232 154 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150017656 Common - transposase IS116/IS110/IS902 family protein Cbei_2804 85 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 150016332 Common - C_GCAxxG_C_C family protein Cbei_1452 15 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 150018542 Nonpathogen - hypothetical protein Cbei_3723 1 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 150017038 Nonpathogen - hypothetical protein Cbei_2169 1 None None None 150017448 Common - Capsular polysaccharide biosynthesis -like protein Cbei_2590 10 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 150017557 Common - acriflavin resistance protein Cbei_2703 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150016815 Common - dihydropyrimidine dehydrogenase Cbei_1943 112 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 150017728 Common - NAD-dependent epimerase/dehydratase Cbei_2880 66 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150019598 Nonpathogen - hypothetical protein Cbei_4789 1 COG4709 COG4709, Predicted membrane protein Function unknown 150015995 Common - aminodeoxychorismate lyase Cbei_1111 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 150015346 Common - methylated-DNA--protein-cysteine methyltransferase Cbei_0456 208 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 150015210 Common - redox-sensing transcriptional repressor Rex Cbei_0320 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 150018977 Common - diguanylate cyclase and metal dependent phosphohydrolase Cbei_4165 195 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 150016290 Common - PHP C-terminal domain protein Cbei_1410 132 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 150019347 Common - ATPase, BadF/BadG/BcrA/BcrD type Cbei_4536 62 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 150018023 Nonpathogen - hypothetical protein Cbei_3191 1 None None None 150017774 Common - efflux transporter, RND family, MFP subunit Cbei_2929 134 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150018444 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3622 162 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150014969 Common - metallophosphoesterase Cbei_0077 93 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150016876 Common - nitrogenase MoFe cofactor biosynthesis protein NifE Cbei_2004 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150018222 Common - hypothetical protein Cbei_3394 6 None None None 150018418 Common - protein of unknown function DUF303, acetylesterase putative Cbei_3596 12 None None None 150018455 Common - short-chain dehydrogenase/reductase SDR Cbei_3633 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150016794 Common - Agmatine deiminase Cbei_1922 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 150015715 Common - GrpE protein Cbei_0829 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 150016574 Common - protein of unknown function DUF322 Cbei_1700 40 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 150018855 Common - microcompartments protein Cbei_4043 36 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 150015987 Common - protein of unknown function UPF0118 Cbei_1103 183 COG0628 PerM, Predicted permease General function prediction only 150018147 Common - transcriptional regulator, TetR family Cbei_3318 20 COG1309 AcrR, Transcriptional regulator Transcription 150017610 Common - Allophanate hydrolase subunit 1 Cbei_2757 111 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 150019831 Nonpathogen - hypothetical protein Cbei_5023 1 None None None 150016353 Common - transposase Cbei_1473 6 None None None 150015049 Common rpsC 30S ribosomal protein S3 Cbei_0157 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 150017335 Common - efflux transporter, RND family, MFP subunit Cbei_2476 180 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150019887 Common - replicative DNA helicase Cbei_5079 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 150017273 Common - MATE efflux family protein Cbei_2413 171 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150019718 Common - GCN5-related N-acetyltransferase Cbei_4910 117 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150018128 Common - ABC transporter related Cbei_3299 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150018769 Common - hypothetical protein Cbei_3957 1 None None None 150015324 Common - peptide chain release factor 2 Cbei_0434 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 150017194 Common - 3D domain protein Cbei_2332 3 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 150019362 Common - fructose-bisphosphate aldolase Cbei_4551 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 150018807 Nonpathogen - hypothetical protein Cbei_3995 1 None None None 150018782 Nonpathogen - small acid-soluble spore H family protein Cbei_3970 2 None None None 150015859 Common - transcriptional regulator, RpiR family Cbei_0973 72 COG1737 RpiR, Transcriptional regulators Transcription 150015252 Nonpathogen - hypothetical protein Cbei_0362 1 None None None 150015033 Common rplA 50S ribosomal protein L1 Cbei_0141 249 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 150018565 Nonpathogen - hypothetical protein Cbei_3746 1 None None None 150015399 Common - protein of unknown function DUF464 Cbei_0509 5 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 150015294 Common prfA peptide chain release factor 1 Cbei_0404 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 150019757 Common recR recombination protein RecR Cbei_4949 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 150019765 Common - integral membrane protein TIGR01906 Cbei_4957 9 COG4478 COG4478, Predicted membrane protein Function unknown 150018133 Nonpathogen - hypothetical protein Cbei_3304 1 None None None 150019653 Common - Mandelate racemase/muconate lactonizing protein Cbei_4845 112 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 150019535 Common - putative cell wall binding repeat-containing protein Cbei_4725 21 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015861 Common - histidinol phosphate phosphatase HisJ family Cbei_0975 43 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 150019456 Common - sugar isomerase (SIS) Cbei_4646 94 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 150015825 Common - D-galactose-binding periplasmic protein precursor Cbei_0939 60 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150015836 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_0950 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150015970 Common - putative galactoside ABC transporter Cbei_1085 79 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019581 Common - methyl-accepting chemotaxis sensory transducer Cbei_4772 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150018820 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Cbei_4008 202 COG0281 SfcA, Malic enzyme Energy production and conversion 150015146 Common - AMP-dependent synthetase and ligase Cbei_0254 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150017155 Nonpathogen - hypothetical protein Cbei_2293 1 None None None 150015011 Common - Zn-dependent hydrolase of the metallo-beta-lactamase superfamily Cbei_0119 75 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 150019116 Common - putative CheW protein Cbei_4304 110 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 150016785 Common - BioY protein Cbei_1913 103 COG1268 BioY, Uncharacterized conserved protein General function prediction only 150018136 Common - beta-lactamase domain protein Cbei_3307 123 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150015102 Common - phosphoglucosamine mutase Cbei_0210 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150019278 Common - Cof-like hydrolase Cbei_4467 112 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150015238 Common - transcriptional regulator, MarR family Cbei_0348 12 COG1846 MarR, Transcriptional regulators Transcription 150018898 Common - methyl-accepting chemotaxis sensory transducer Cbei_4086 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016325 Common - protein of unknown function DUF1002 Cbei_1445 11 COG4086 COG4086, Predicted secreted protein Function unknown 150018111 Common - hypothetical protein Cbei_3280 4 None None None 150019616 Common - transcriptional regulator, RpiR family Cbei_4807 28 COG1737 RpiR, Transcriptional regulators Transcription 150017857 Common - putative transcriptional regulator, Crp/Fnr family Cbei_3016 186 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150016564 Common - elongation factor P Cbei_1690 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 150016039 Common - ribosomal protein L28 Cbei_1155 54 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 150016120 Common - glycoside hydrolase family 2, TIM barrel Cbei_1236 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 150018847 Common - putative transcriptional regulator, GntR family Cbei_4035 171 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150015359 Common - protein of unknown function UPF0079 Cbei_0469 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 150017358 Common - PTS system Galactitol-specific IIC component Cbei_2500 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 150018942 Common - Methyltransferase type 11 Cbei_4130 194 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150019314 Common - ABC transporter related Cbei_4503 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150017182 Common - PTS system, trehalose-specific IIBC subunit Cbei_2320 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150018094 Common - putative cell wall binding repeat-containing protein Cbei_3263 3 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018700 Common - hypothetical protein Cbei_3884 71 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 150015228 Common - Transaldolase Cbei_0338 151 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150015891 Common - dihydroorotate dehydrogenase 1B Cbei_1005 234 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 150015988 Common alaS alanyl-tRNA synthetase Cbei_1104 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150019601 Common - transposase (21) Cbei_4792 17 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 150015181 Common - 5-formyltetrahydrofolate cyclo-ligase Cbei_0291 193 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 150018150 Common - integral membrane sensor signal transduction histidine kinase Cbei_3321 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019184 Nonpathogen - hypothetical protein Cbei_4372 1 None None None 150015875 Nonpathogen - O-antigen polymerase Cbei_0989 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 150018761 Nonpathogen - hypothetical protein Cbei_3949 1 None None None 150016115 Common - binding-protein-dependent transport systems inner membrane component Cbei_1231 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150019244 Common - ABC transporter related Cbei_4433 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 150018091 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cbei_3260 76 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150017561 Common - PTS system, lactose/cellobiose family IIC subunit Cbei_2707 37 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 150017319 Common - 2-keto-3-deoxygluconate permease Cbei_2459 27 None None None 150015532 Common - TPR repeat-containing protein Cbei_0643 9 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 150018522 Common - transport system permease protein Cbei_3703 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150015871 Common - glycosyl transferase, WecB/TagA/CpsF family Cbei_0985 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 150015842 Common - PTS system sorbose subfamily IIB component Cbei_0956 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150018373 Common - transcriptional regulator, XRE family Cbei_3549 56 COG1476 COG1476, Predicted transcriptional regulators Transcription 150015543 Common - diguanylate cyclase Cbei_0654 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 150015330 Common - oxidoreductase domain protein Cbei_0440 162 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150019865 Common - hypothetical protein Cbei_5057 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 150018702 Common - putative transcriptional regulator, TetR family Cbei_3886 18 COG1309 AcrR, Transcriptional regulator Transcription 150018003 Common - multi-sensor signal transduction histidine kinase Cbei_3169 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150016775 Nonpathogen - hypothetical protein Cbei_1902 1 None None None 150015539 Common - hypothetical protein Cbei_0650 6 None None None 150016343 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Cbei_1463 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 150019480 Common - 6-phospho-beta-glucosidase Cbei_4670 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 150017668 Common - hypothetical protein Cbei_2817 3 None None None 150018831 Common - CheA signal transduction histidine kinase Cbei_4019 151 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 150017269 Common - protein of unknown function DUF6, transmembrane Cbei_2409 101 COG2510 COG2510, Predicted membrane protein Function unknown 150018216 Common - putative tail fiber-related protein Cbei_3388 22 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 150016166 Common - precorrin-2 dehydrogenase Cbei_1284 8 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 150017366 Common - protein of unknown function UPF0061 Cbei_2508 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 150016743 Nonpathogen - hypothetical protein Cbei_1870 1 None None None 150015406 Common - pseudouridine synthase, RluA family Cbei_0516 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150017469 Common - hypothetical protein Cbei_2611 55 COG5495 COG5495, Uncharacterized conserved protein Function unknown 150018994 Common - methyl-accepting chemotaxis sensory transducer Cbei_4182 191 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150019885 Common - pyrroline-5-carboxylate reductase Cbei_5077 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 150018178 Common - Citrate transporter Cbei_3350 41 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 150018465 Common - transcriptional regulator, TetR family Cbei_3644 95 COG1309 AcrR, Transcriptional regulator Transcription 150019524 Nonpathogen - hypothetical protein Cbei_4714 1 None None None 150017054 Nonpathogen - hypothetical protein Cbei_2185 1 None None None 150016053 Common - acyl carrier protein Cbei_1169 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150019155 Common - regulatory protein GntR, HTH Cbei_4343 116 COG1725 COG1725, Predicted transcriptional regulators Transcription 150019384 Common - chorismate mutase Cbei_4573 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 150018620 Common - formate dehydrogenase, alpha subunit Cbei_3801 202 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 150015025 Common - RNA methyltransferase, TrmH family, group 3 Cbei_0133 218 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150016920 Common - protein of unknown function DUF214 Cbei_2050 31 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150018654 Common - protein of unknown function DUF975 Cbei_3837 6 COG5523 COG5523, Predicted integral membrane protein Function unknown 150015467 Common - serine O-acetyltransferase Cbei_0578 207 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 150016668 Common - dihydrodipicolinate reductase Cbei_1795 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 150019301 Common - phosphomethylpyrimidine kinase Cbei_4490 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 150019593 Common - hypothetical protein Cbei_4784 5 None None None 150015121 Common - Excinuclease ABC, C subunit domain protein Cbei_0229 93 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 150016417 Common - adenine phosphoribosyltransferase Cbei_1539 188 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 150015136 Common - phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Cbei_0244 71 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 150015296 Common - Sua5/YciO/YrdC/YwlC family protein Cbei_0406 242 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 150018839 Common - putative CoA-substrate-specific enzyme activase Cbei_4027 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 150017171 Common - anaerobic cobalt chelatase Cbei_2309 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 150015806 Common - hypothetical protein Cbei_0920 3 None None None 150016834 Common - Sporulation stage II, protein M Cbei_1962 12 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 150018350 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cbei_3526 46 COG0778 NfnB, Nitroreductase Energy production and conversion 150019235 Common - hypothetical protein Cbei_4424 22 None None None 150018891 Common - hypothetical protein Cbei_4079 40 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 150018751 Common - D-galactose-binding periplasmic protein precursor Cbei_3939 81 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019438 Nonpathogen - hypothetical protein Cbei_4628 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 150016224 Nonpathogen - hypothetical protein Cbei_1342 1 COG2810 COG2810, Predicted type IV restriction endonuclease Defense mechanisms 150015446 Common - putative transcriptional regulator, MerR family Cbei_0557 55 COG0789 SoxR, Predicted transcriptional regulators Transcription 150015688 Common coaE dephospho-CoA kinase Cbei_0802 190 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 150016588 Nonpathogen - hypothetical protein Cbei_1714 1 None None None 150016959 Common - binding-protein-dependent transport systems inner membrane component Cbei_2090 187 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150016268 Common - pseudouridine synthase, RluA family Cbei_1387 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150018104 Common - PTS system, beta-glucoside-specific IIABC subunit Cbei_3273 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150017352 Common - D-galactose-binding protein Cbei_2494 61 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150017550 Nonpathogen - hypothetical protein Cbei_2696 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 150016089 Common truB tRNA pseudouridine synthase B Cbei_1205 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 150015617 Common - Alanine racemase Cbei_0731 130 COG1609 PurR, Transcriptional regulators Transcription 150018920 Common - transcriptional regulator, HxlR family Cbei_4108 147 COG1733 COG1733, Predicted transcriptional regulators Transcription 150019165 Common - amino acid permease-associated region Cbei_4353 115 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150019289 Common - hypothetical protein Cbei_4478 10 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 150016801 Common - protein kinase Cbei_1929 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 150017921 Common - transcriptional regulator, HxlR family Cbei_3082 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 150015318 Common - Methionine adenosyltransferase Cbei_0428 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 150015771 Common - hypothetical protein Cbei_0885 18 None None None 150016927 Common - protein of unknown function DUF1304 Cbei_2057 33 COG3759 COG3759, Predicted membrane protein Function unknown 150018164 Common - transcriptional regulator, TetR family Cbei_3335 72 COG1309 AcrR, Transcriptional regulator Transcription 150015509 Common - Nitrogenase Cbei_0620 60 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 150018772 Common - protein of unknown function DUF955 Cbei_3960 2 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 150015305 Common - F0F1 ATP synthase subunit delta Cbei_0415 176 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 150015664 Common - Thioredoxin-disulfide reductase Cbei_0778 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150017388 Common - ATP-dependent metalloprotease FtsH Cbei_2530 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150015454 Common - hypothetical protein Cbei_0565 1 None None None 150017423 Common mutL DNA mismatch repair protein Cbei_2565 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 150015676 Common - ABC transporter related Cbei_0790 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150014992 Common - ATP-dependent metalloprotease FtsH Cbei_0100 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150014908 Nonpathogen - hypothetical protein Cbei_0016 1 None None None 150017215 Common - hypothetical protein Cbei_2353 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150018183 Common - transcriptional regulator, HxlR family Cbei_3355 125 COG1733 COG1733, Predicted transcriptional regulators Transcription 150019474 Common - polysaccharide deacetylase Cbei_4664 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150015913 Common - protein of unknown function DUF378 Cbei_1027 1 COG2155 COG2155, Uncharacterized conserved protein Function unknown 150019564 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Cbei_4755 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 150017737 Common - amino acid permease-associated region Cbei_2889 84 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 150015050 Common rplP 50S ribosomal protein L16 Cbei_0158 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 150019226 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cbei_4415 74 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150016722 Common - FeS assembly protein SufB Cbei_1849 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 150017641 Common - L-lactate dehydrogenase Cbei_2789 164 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 150014983 Common - histone family protein DNA-binding protein Cbei_0091 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 150017136 Common - hypothetical protein Cbei_2273 6 None None None 150018531 Common - cobalt ABC transporter, inner membrane subunit CbiQ Cbei_3712 50 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 150016513 Nonpathogen - hypothetical protein Cbei_1637 2 None None None 150019815 Common - LrgA family protein Cbei_5007 75 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 150017645 Common - ABC transporter related Cbei_2793 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150016672 Common - Methyltransferase type 11 Cbei_1799 45 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 150018283 Common - transcriptional regulator, XRE family Cbei_3456 55 COG1476 COG1476, Predicted transcriptional regulators Transcription 150015073 Common rplQ 50S ribosomal protein L17 Cbei_0181 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 150016265 Nonpathogen - hypothetical protein Cbei_1384 1 None None None 150015149 Common - malonyl CoA-acyl carrier protein transacylase Cbei_0257 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 150015932 Common - band 7 protein Cbei_1046 219 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 150019537 Common - putative cell wall binding repeat-containing protein Cbei_4727 8 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150018359 Common - protein of unknown function DUF1648 Cbei_3535 20 COG5658 COG5658, Predicted integral membrane protein Function unknown 150015271 Common - ABC-type sugar transport system periplasmic component-like protein Cbei_0381 7 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150018333 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cbei_3508 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150015572 Common - AMP-dependent synthetase and ligase Cbei_0684 184 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150017168 Common - phage integrase family protein Cbei_2306 168 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150017381 Common - nitrite and sulphite reductase 4Fe-4S region Cbei_2523 164 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 150015506 Common - binding-protein-dependent transport systems inner membrane component Cbei_0617 187 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150018345 Common - transcriptional regulator, RpiR family Cbei_3520 83 COG1737 RpiR, Transcriptional regulators Transcription 150015863 Common - major facilitator superfamily MFS_1 Cbei_0977 146 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150018737 Common - integral membrane sensor signal transduction histidine kinase Cbei_3923 86 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150016985 Common - metal dependent phosphohydrolase Cbei_2116 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 150016952 Common - putative transcriptional regulator, GntR family Cbei_2083 228 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 150018089 Nonpathogen - hypothetical protein Cbei_3258 1 None None None 150015472 Common - membrane protein Cbei_0583 1 COG1971 COG1971, Predicted membrane protein Function unknown 150017207 Common - small acid-soluble spore protein, alpha/beta type Cbei_2345 15 None None None 150019526 Common - peptide chain release factor 3 Cbei_4716 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 150016364 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cbei_1484 191 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 150016171 Common - protein of unknown function DUF208 Cbei_1289 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 150015217 Common - Ferredoxin hydrogenase Cbei_0327 78 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 150017780 Common - GCN5-related N-acetyltransferase Cbei_2936 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 150017953 Nonpathogen - hypothetical protein Cbei_3114 1 None None None 150019457 Common - Orotidine 5'-phosphate decarboxylase Cbei_4647 57 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 150017301 Common - NUDIX hydrolase Cbei_2441 12 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150018552 Common - hypothetical protein Cbei_3733 2 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 150016653 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cbei_1780 42 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150018581 Common - transport system permease protein Cbei_3762 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150015286 Common - Domain of unknown function DUF1934 Cbei_0396 8 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 150017123 Common - Sterol 3-beta-glucosyltransferase Cbei_2258 34 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 150019221 Common - spermidine synthase Cbei_4410 134 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 150019052 Common - Cof-like hydrolase Cbei_4240 101 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150017541 Common - transcription activator, effector binding Cbei_2686 36 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 150016973 Common - beta-lactamase domain protein Cbei_2104 77 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150019731 Common - transcriptional regulator, MarR family Cbei_4923 128 COG1846 MarR, Transcriptional regulators Transcription 150015488 Common tpiA triosephosphate isomerase Cbei_0599 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 150019334 Common - nitroreductase Cbei_4523 43 COG0778 NfnB, Nitroreductase Energy production and conversion 150014938 Common ileS isoleucyl-tRNA synthetase Cbei_0046 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150019252 Common - glycoside hydrolase, clan GH-D Cbei_4441 41 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 150015945 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Cbei_1059 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 150019530 Common - glycerophosphoryl diester phosphodiesterase Cbei_4720 161 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 150014989 Common - Sporulation stage II, protein E Cbei_0097 19 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 150016134 Nonpathogen - hypothetical protein Cbei_1251 2 None None None 150018629 Common - ROK family protein Cbei_3810 169 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 150017046 Nonpathogen - hypothetical protein Cbei_2177 1 None None None 150019795 Nonpathogen - hypothetical protein Cbei_4987 1 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 150014919 Common - short-chain dehydrogenase/reductase SDR Cbei_0027 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 150017937 Common - hypothetical protein Cbei_3098 12 None None None 150016105 Common - adenylosuccinate lyase Cbei_1221 194 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 150016990 Common - alpha/beta hydrolase fold Cbei_2121 99 COG2267 PldB, Lysophospholipase Lipid metabolism 150017485 Common - hypothetical protein Cbei_2629 2 None None None 150017013 Common - ABC transporter related Cbei_2144 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150015157 Nonpathogen - hypothetical protein Cbei_0266 1 None None None 150019859 Nonpathogen - Protein of unknown function CGGC region Cbei_5051 5 COG5561 COG5561, Predicted metal-binding protein Function unknown 150017742 Common - extracellular solute-binding protein, family 1 Cbei_2894 119 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 150019852 Common - inner-membrane translocator Cbei_5044 141 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 150019494 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Cbei_4684 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 150017329 Common - putative cell wall binding repeat-containing protein Cbei_2469 6 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150019551 Common - capsular exopolysaccharide family Cbei_4741 157 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150017379 Common - transcriptional regulator, Fis family Cbei_2521 151 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150018873 Common - pyruvate formate-lyase Cbei_4061 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150015479 Common - integral membrane sensor signal transduction histidine kinase Cbei_0590 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150016405 Common - Radical SAM domain protein Cbei_1527 37 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 150014970 Common murC UDP-N-acetylmuramate--L-alanine ligase Cbei_0078 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 150018652 Common - acetoacetate decarboxylase Cbei_3835 18 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 150017375 Common - conserved membrane protein, predicted permease Cbei_2517 17 COG0730 COG0730, Predicted permeases General function prediction only 150019292 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cbei_4481 244 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 150018726 Common - VanZ family protein Cbei_3912 7 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 150018544 Common - Domain of unknown function DUF1906 Cbei_3725 10 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 150016611 Common - NAD(P)H dehydrogenase (quinone) Cbei_1737 100 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 150017749 Common - PTS system sorbose subfamily IIB component Cbei_2902 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 150018926 Common - GTP-binding protein, HSR1-related Cbei_4114 21 None None None 150019413 Common - hypothetical protein Cbei_4603 14 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 150015082 Common - fumarate hydratase Cbei_0190 147 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 150015110 Common - ketol-acid reductoisomerase Cbei_0218 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 150018795 Common - PAS/PAC sensor signal transduction histidine kinase Cbei_3983 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150015822 Common - LrgA family protein Cbei_0936 64 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 150016905 Common - acyl-CoA dehydrogenase domain protein Cbei_2035 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150018363 Common - binding-protein-dependent transport systems inner membrane component Cbei_3539 128 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 150015959 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Cbei_1073 171 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 150016858 Common - molybdopterin dehydrogenase, FAD-binding Cbei_1986 92 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 150019802 Common - transposase Cbei_4994 6 None None None 150017309 Common - electron transport complex, RnfABCDGE type, C subunit Cbei_2449 76 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 150018230 Common - Phosphate acetyltransferase Cbei_3402 43 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 150017884 Nonpathogen - hypothetical protein Cbei_3043 1 None None None 150016849 Common - diaminopropionate ammonia-lyase Cbei_1977 138 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 150019871 Common - hypothetical protein Cbei_5063 1 None None None 150016198 Common - ATP phosphoribosyltransferase Cbei_1316 209 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 150015692 Common - phage infection protein, putative Cbei_0806 73 COG1511 COG1511, Predicted membrane protein Function unknown 150015798 Nonpathogen - hypothetical protein Cbei_0912 2 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 150015669 Common - Sulfite reductase, Subunit A Cbei_0783 31 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 150015559 Common - hypothetical protein Cbei_0670 24 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 150018584 Common - glycoside hydrolase, family 3 domain protein Cbei_3765 102 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150019412 Common - RelA/SpoT domain protein Cbei_4602 43 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 150019805 Common - transcriptional regulator, XRE family Cbei_4997 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 150016347 Common - metal dependent phosphohydrolase Cbei_1467 9 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 150017804 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Cbei_2961 28 COG1433 COG1433, Uncharacterized conserved protein Function unknown 150017325 Common - HAD-superfamily hydrolase, subfamily IIB Cbei_2465 70 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 150019211 Common - Serine/threonine protein phosphatase-like protein Cbei_4400 27 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 150018721 Common - nitroreductase Cbei_3906 183 COG0778 NfnB, Nitroreductase Energy production and conversion 150017246 Common - xylulokinase Cbei_2384 180 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 150017040 Common - signal transduction histidine kinase, LytS Cbei_2171 224 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150017827 Common - proton-translocating NADH-quinone oxidoreductase, chain N Cbei_2986 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 150019647 Common - PTS system, glucose subfamily, IIA subunit Cbei_4838 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150015436 Common - Transketolase, central region Cbei_0546 231 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 150015591 Common - pyruvate formate-lyase Cbei_0705 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 150015830 Common - protein of unknown function DUF710 Cbei_0944 139 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150018413 Common - nitroreductase Cbei_3590 77 COG0778 NfnB, Nitroreductase Energy production and conversion 150016812 Common - binding-protein-dependent transport systems inner membrane component Cbei_1940 116 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 150019743 Common - regulatory protein, LuxR Cbei_4935 34 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 150018434 Common - PhnB protein Cbei_3612 14 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 150017964 Common - membrane -like protein Cbei_3126 28 COG2364 COG2364, Predicted membrane protein Function unknown 150018716 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cbei_3900 25 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150018409 Nonpathogen - hypothetical protein Cbei_3585 1 None None None 150019778 Common - NADPH-dependent FMN reductase Cbei_4970 49 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 150018661 Common - GCN5-related N-acetyltransferase Cbei_3844 7 COG0456 RimI, Acetyltransferases General function prediction only 150015582 Common - guanine-specific ribonuclease N1 and T1 Cbei_0696 10 None None None 150018618 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Cbei_3799 96 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 150017605 Common - hypothetical protein Cbei_2752 14 None None None 150019145 Common - DltD, C-terminal domain protein Cbei_4333 14 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 150018294 Common - putative transcriptional regulator, MerR family Cbei_3467 105 COG0789 SoxR, Predicted transcriptional regulators Transcription 150016620 Common - cyclic nucleotide-binding protein Cbei_1746 54 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150016695 Common - DEAD/DEAH box helicase domain protein Cbei_1822 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150018637 Common - coenzyme A transferase Cbei_3819 102 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 150017866 Common - nitroreductase Cbei_3025 61 COG0778 NfnB, Nitroreductase Energy production and conversion 150019824 Nonpathogen - hypothetical protein Cbei_5016 1 None None None 150017501 Common - ABC transporter related Cbei_2645 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150019158 Common - Succinylglutamate desuccinylase/aspartoacylase Cbei_4346 49 COG3608 COG3608, Predicted deacylase General function prediction only 150015515 Common - NLPA lipoprotein Cbei_0626 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 150015811 Common - phage-like element pbsx protein XkdT Cbei_0925 3 None None None 150019754 Common - SH3, type 3 domain protein Cbei_4946 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 150015950 Common - Tetratricopeptide TPR_2 repeat protein Cbei_1064 126 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 150016629 Common - tryptophan synthase, alpha subunit Cbei_1755 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 150019332 Common - ornithine carbamoyltransferase Cbei_4521 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 150017970 Common - conserved hypothetical protein 698 Cbei_3132 113 COG2855 COG2855, Predicted membrane protein Function unknown 150016991 Common - amino acid/peptide transporter Cbei_2122 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 150016003 Common - peptidase U4, sporulation factor SpoIIGA Cbei_1119 11 None None None 150018968 Common - peptidase M16 domain protein Cbei_4156 183 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150018815 Common - Exonuclease, RNase T and DNA polymerase III Cbei_4003 11 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 150018862 Common - Methionine adenosyltransferase Cbei_4050 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 150016580 Common - 1-deoxy-D-xylulose-5-phosphate synthase Cbei_1706 229 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 150019615 Common - phosphotransferase system, EIIC Cbei_4806 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150018640 Nonpathogen - hypothetical protein Cbei_3822 1 None None None 150018181 Common - glycoside hydrolase, family 18 Cbei_3353 43 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 150014944 Common - nucleoside recognition domain protein Cbei_0052 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 150017762 Common - acriflavin resistance protein Cbei_2917 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150015753 Nonpathogen - hypothetical protein Cbei_0867 1 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150014929 Common - Radical SAM domain protein Cbei_0037 44 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 150019125 Common - aminotransferase, class IV Cbei_4313 177 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150019692 Common - Domain of unknown function DUF1836 Cbei_4884 8 None None None 150018758 Nonpathogen - hypothetical protein Cbei_3946 1 None None None 150019212 Common - protein phosphatase 2C domain protein Cbei_4401 32 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 150016293 Common - membrane protein Cbei_1413 2 None None None 150016141 Common - cobalt-precorrin-6x reductase Cbei_1258 66 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 150016663 Common - single-strand DNA-binding protein Cbei_1790 11 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150019762 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Cbei_4954 174 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 150017578 Common - response regulator receiver sensor signal transduction histidine kinase Cbei_2725 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 150015460 Common - hypothetical protein Cbei_0571 1 None None None 150015115 Common - Alcohol dehydrogenase GroES domain protein Cbei_0223 203 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 150016233 Nonpathogen - hypothetical protein Cbei_1351 1 None None None 150019785 Common - PTS system, glucose-like IIB subunint Cbei_4977 50 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 150019544 Common - galactoside O-acetyltransferase Cbei_4734 65 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 150015278 Common - peptidase U57, YabG Cbei_0388 11 None None None 150015554 Common - methyl-accepting chemotaxis sensory transducer Cbei_0665 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150014895 Common - S4 region, YaaA Cbei_0003 38 COG2501 COG2501, Uncharacterized conserved protein Function unknown 150016412 Common yajC preprotein translocase subunit YajC Cbei_1534 37 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 150015164 Common - major facilitator superfamily MFS_1 Cbei_0274 89 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 150017615 Common - aminotransferase, class IV Cbei_2762 176 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150019620 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Cbei_4811 205 COG0388 COG0388, Predicted amidohydrolase General function prediction only 150015326 Common - integral membrane sensor signal transduction histidine kinase Cbei_0436 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150019068 Common - flagellar biosynthetic protein FliP Cbei_4256 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 150017023 Common - drug resistance transporter, EmrB/QacA subfamily Cbei_2154 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150017262 Common recX recombination regulator RecX Cbei_2402 25 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 150017843 Common - protein of unknown function DUF81 Cbei_3002 141 COG0730 COG0730, Predicted permeases General function prediction only 150017926 Common - hypothetical protein Cbei_3087 4 None None None 150019078 Common - Flagellar biosynthesis/type III secretory pathway -like protein Cbei_4266 22 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 150019624 Nonpathogen - hypothetical protein Cbei_4815 1 None None None 150019771 Common - integral membrane sensor signal transduction histidine kinase Cbei_4963 108 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 150017871 Common - Radical SAM domain protein Cbei_3030 99 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150018204 Nonpathogen - protein of unknown function DUF1646 Cbei_3376 11 COG4756 COG4756, Predicted cation transporter General function prediction only 150017291 Common - ABC transporter related Cbei_2431 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150017698 Common - methyl-accepting chemotaxis sensory transducer Cbei_2849 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 150016420 Common - beta-lactamase domain protein Cbei_1542 223 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150017620 Common - inner-membrane translocator Cbei_2767 158 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 150018395 Common - FMN-binding domain protein Cbei_3571 7 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 150019139 Common - oligoendopeptidase F Cbei_4327 93 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 150017754 Common - N-acetylgalactosamine-specific PTS system transporter subunit IIC Cbei_2907 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 150017814 Common - NLP/P60 protein Cbei_2971 151 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane