Orientia tsutsugamushi Boryong, complete genome NC_009488 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 148284442 Common - ATP synthase subunit B OTBS_0773 18 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 148284733 Common int phage-related integrase OTBS_1338 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284180 Common trbG/virB9 conjugal transfer protein OTBS_0338 56 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 148284563 Common hemH ferrochelatase OTBS_1009 176 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 148285091 Pathogen - hypothetical protein OTBS_2014 1 None None None 148284287 Common traB conjugative pilus assembly protein OTBS_0489 14 None None None 148284084 Common truB tRNA pseudouridine synthase B OTBS_0164 234 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 148285028 Pathogen traV conjugative transfer protein OTBS_1903 1 None None None 148285129 Common - hypothetical protein OTBS_2087 2 None None None 148284510 Common ank1B2 ankyrin repeat protein with 5 ankyrin repeats OTBS_0912 61 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148285131 Common tnD transposase and inactivated derivative OTBS_2092 94 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284627 Pathogen - hypothetical protein OTBS_1130 1 None None None 148284096 Pathogen - hypothetical protein OTBS_0194 1 None None None 148284025 Common - hypothetical protein OTBS_0057 27 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 148284755 Common petB ubiquinol-cytochrome c reductase, cytochrome b OTBS_1397 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 148284081 Pathogen ank2A2 ankyrin repeat protein with 1d ankyrin repeats OTBS_0161 1 None None None 148285148 Common rhp8 ompA-like, putative autotransporter OTBS_2137 2 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 148284376 Common traV conjugative transfer protein OTBS_0641 2 None None None 148284884 Common nuoF NADH dehydrogenase I chain F OTBS_1632 174 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148284246 Common tchA hypothetical protein OTBS_0416 2 None None None 148284199 Common rplF 50S ribosomal protein L6 OTBS_0361 230 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 148284916 Pathogen - hypothetical protein OTBS_1690 1 None None None 148284509 Common dnaB14 replicative DNA helicase OTBS_0911 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 148284011 Common - hypothetical protein OTBS_0020 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148284631 Common - hypothetical protein OTBS_1136 62 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148284404 Common mraW S-adenosyl-methyltransferase MraW OTBS_0702 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 148284948 Pathogen rhp4 hypothetical protein OTBS_1743 1 None None None 148284064 Common dsbB disulfide bond formation protein OTBS_0143 31 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 148284280 Common ank1C3 ankyrin repeat protein with 5 ankyrin repeats OTBS_0476 55 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148285138 Common hkp44 putative signal transduction histidine kinase OTBS_2100 2 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284955 Common ank1C12 ankyrin repeat protein with 5 ankyrin repeats OTBS_1753 55 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284526 Common traB conjugative pilus assembly protein OTBS_0938 24 None None None 148284519 Common obgE GTPase ObgE OTBS_0924 249 COG0536 Obg, Predicted GTPase General function prediction only 148284308 Common tpr1B7 tetratricopeptide repeat protein with 5 trp repeats OTBS_0524 131 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284373 Common trbC conjugative transfer protein OTBS_0637 9 None None None 148284832 Common kefB Glutathione-regulated potassium-efflux system protein OTBS_1539 218 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 148284809 Common ruvA Holliday junction DNA helicase motor protein OTBS_1497 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 148284309 Common trbC conjugative transfer protein OTBS_0526 9 None None None 148284914 Common rhp8 ompA-like, putative autotransporter OTBS_1686 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148284784 Common traD_Ti conjugative transfer protein OTBS_1450 3 None None None 148284139 Common fbcH cytochrome c1, heme protein precursor OTBS_0259 78 COG2857 CYT1, Cytochrome c1 Energy production and conversion 148285085 Pathogen rhp4 hypothetical protein OTBS_2008 1 None None None 148284490 Common rhp8 ompA-like, putative autotransporter OTBS_0864 2 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 148284961 Common tpr1B17 tetratricopeptide repeat protein with 1 trp repeats OTBS_1767 7 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 148284749 Pathogen - hypothetical protein OTBS_1376 1 None None None 148284941 Common tchB hypothetical protein OTBS_1729 2 None None None 148284156 Common TrbL/VirB6 conjugal transfer protein OTBS_0285 6 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 148284344 Common folC folylpolyglutamate synthase OTBS_0584 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 148284363 Common hkp10 putative signal transduction histidine kinase OTBS_0618 49 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284170 Common traC conjugative transfer protein OTBS_0316 5 None None None 148284864 Pathogen - hypothetical protein OTBS_1598 1 None None None 148284680 Common - GTP-binding protein LepA OTBS_1228 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 148284521 Common - hypothetical protein OTBS_0926 6 None None None 148284118 Common - hypothetical protein OTBS_0220 19 None None None 148284316 Common tlc ATP/ADP translocase OTBS_0547 7 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 148284551 Common traV conjugative transfer protein OTBS_0987 2 None None None 148284849 Common glnA glutamine synthetase OTBS_1575 133 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 148285082 Common tnE transposase and inactivated derivative OTBS_2004 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284996 Common hflC putative membrane protease, stomatin/prohibitin-like protein OTBS_1836 209 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148285027 Common tchB hypothetical protein OTBS_1896 2 None None None 148284605 Common trbC conjugative transfer protein OTBS_1086 9 None None None 148284279 Common spoT7 spoT-like ppGpp hydrolase OTBS_0475 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284360 Common ank1C4 ankyrin repeat protein with 5 ankyrin repeats OTBS_0614 86 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284447 Pathogen - hypothetical protein OTBS_0782 1 None None None 148284643 Common hkp25 putative signal transduction histidine kinase OTBS_1165 111 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284414 Common trbC conjugative transfer protein OTBS_0718 9 None None None 148284904 Common traV conjugative transfer protein OTBS_1671 2 None None None 148284695 Pathogen rhp7 hypothetical protein OTBS_1262 1 None None None 148284585 Common - hypothetical protein OTBS_1045 16 None None None 148284253 Common - putative membrane-associated zinc-dependent metalloprotease OTBS_0436 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 148284979 Common coxA cytochrome c oxidase polypeptide I OTBS_1800 173 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 148284168 Common - hypothetical protein OTBS_0314 2 None None None 148284938 Common int phage-related integrase OTBS_1726 137 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284534 Common efp elongation factor P OTBS_0947 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 148284109 Common rplA 50S ribosomal protein L1 OTBS_0211 242 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 148284072 Common sucC succinyl-CoA synthetase beta chain OTBS_0151 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 148284495 Common traV conjugative transfer protein OTBS_0881 2 None None None 148284468 Pathogen - hypothetical protein OTBS_0822 1 None None None 148284717 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase OTBS_1307 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148284672 Common carD putative transcriptional factor regulator OTBS_1218 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 148284132 Common maf Maf-like protein OTBS_0250 188 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 148284779 Common traV conjugative transfer protein OTBS_1440 2 None None None 148284713 Common dam16 site-specific DNA adenine methylase OTBS_1297 2 None None None 148284815 Common tchA hypothetical protein OTBS_1507 2 None None None 148284804 Pathogen - hypothetical protein OTBS_1492 1 None None None 148284457 Pathogen - hypothetical protein OTBS_0803 1 None None None 148284774 Common dam21 site-specific DNA adenine methylase OTBS_1432 52 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284434 Common tpr1B10 tetratricopeptide and ankyrin rep with 1 trp repeats OTBS_0758 2 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 148284296 Common ccmE cytochrome c-type biogenesis protein OTBS_0500 93 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 148284553 Common tchB hypothetical protein OTBS_0989 2 None None None 148284231 Common trmD tRNA (guanine-N(1)-)-methyltransferase OTBS_0397 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 148284261 Common uvrD ATP-dependent helicase, UvrD/rep/AddA family OTBS_0444 227 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 148284018 Common traB conjugative pilus assembly protein OTBS_0035 24 None None None 148285052 Common virB6-2 type IV secretion system protein OTBS_1952 6 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 148285041 Pathogen - hypothetical protein OTBS_1921 1 None None None 148284481 Pathogen rhp9 putative RNA-binding protein OTBS_0849 2 None None None 148284202 Common rplE 50S ribosomal protein L5 OTBS_0364 247 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 148285179 Common - hypothetical protein OTBS_2179 32 COG2938 COG2938, Uncharacterized conserved protein Function unknown 148285172 Common - hypothetical protein OTBS_2170 199 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 148284290 Common - hypothetical protein OTBS_0493 193 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 148284107 Common rplL 50S ribosomal protein L7/L12 OTBS_0209 212 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 148284429 Pathogen rhp7 hypothetical protein OTBS_0749 1 None None None 148285152 Common ppa inorganic pyrophosphatase OTBS_2146 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 148284546 Common traD_Ti conjugative transfer protein OTBS_0964 3 None None None 148284332 Common argS arginyl-tRNA synthetase OTBS_0571 245 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284574 Pathogen - hypothetical protein OTBS_1024 1 None None None 148284668 Common int phage-related integrase OTBS_1208 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284129 Common dam3 site-specific DNA adenine methylase OTBS_0245 101 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284829 Common murG N-acetylglucosaminyl transferase OTBS_1530 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 148284984 Pathogen - hypothetical protein OTBS_1805 1 None None None 148284900 Common xth1 exodeoxyribonuclease III OTBS_1662 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 148283998 Common dnaA chromosomal replication initiation protein OTBS_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148284658 Pathogen - hypothetical protein OTBS_1192 1 None None None 148285164 Common nuoJ NADH dehydrogenase subunit J OTBS_2162 155 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 148284009 Common tolB protein precursor OTBS_0018 162 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 148284926 Common - esterase OTBS_1707 86 COG0400 COG0400, Predicted esterase General function prediction only 148284146 Common abcZ ABC transporter, ATP-binding protein OTBS_0269 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148284345 Common ppiC putative peptidylprolyl isomerase OTBS_0585 70 None None None 148284381 Pathogen - hypothetical protein OTBS_0658 1 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 148284297 Common qor NADP-dependent quinone oxidoreductase OTBS_0501 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 148284444 Common ftsK cell division protein FtsK OTBS_0779 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 148284033 Common tnD transposase and inactivated derivative OTBS_0082 94 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284323 Common dapE succinyl-diaminopimelate desuccinylase OTBS_0555 204 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148285011 Pathogen - hypothetical protein OTBS_1856 1 None None None 148284153 Common - hypothetical protein OTBS_0282 2 None None None 148284091 Common sppA Periplasmic serine proteases (ClpP class) OTBS_0186 179 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148284252 Common omp1 outer membrane protein OTBS_0435 158 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 148284793 Common - hypothetical protein OTBS_1468 2 None None None 148284357 Common - putative translation factor protein OTBS_0605 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 148284162 Common - hypothetical protein OTBS_0302 2 None None None 148284338 Common atpG H(+)-transporting two-sector ATPase F(1) gamma subunit precursor OTBS_0577 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 148284023 Common ybjR N-acetylmuramoyl-L-alanine amidase OTBS_0048 95 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 148284765 Common - hypothetical protein OTBS_1418 3 None None None 148284891 Common truA tRNA pseudouridine synthase A OTBS_1643 224 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 148284981 Common rplY 50S ribosomal protein L25/general stress protein Ctc OTBS_1802 183 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 148284540 Common virB4-2 virB4 protein precursor OTBS_0953 43 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 148284052 Pathogen - hypothetical protein OTBS_0120 1 None None None 148285016 Common traV conjugative transfer protein OTBS_1871 2 None None None 148284098 Common - hypothetical protein OTBS_0200 4 None None None 148284141 Common grpE heat shock molecular chaperone protein OTBS_0261 171 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 148284875 Pathogen - hypothetical protein OTBS_1619 1 None None None 148285122 Common traB conjugative pilus assembly protein OTBS_2075 25 None None None 148284000 Common virB8 type IV secretion system protein OTBS_0003 25 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 148284530 Common int phage-related integrase OTBS_0942 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284611 Pathogen - hypothetical protein OTBS_1096 1 None None None 148285107 Pathogen rhp6 putative ompA-like autotransporter OTBS_2049 1 None None None 148285034 Common rhp8 ompA-like, putative autotransporter OTBS_1913 29 None None None 148284953 Pathogen rhp5 hypothetical protein OTBS_1750 1 None None None 148284013 Common tnD transposase and inactivated derivative OTBS_0025 109 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284326 Common rplT 50S ribosomal protein L20 OTBS_0558 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 148284319 Common rpsF 30S ribosomal protein S6 OTBS_0550 117 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 148284906 Common traE conjugative transfer protein OTBS_1674 2 None None None 148284912 Pathogen - hypothetical protein OTBS_1684 1 None None None 148284062 Common secG preprotein translocase subunit SecG OTBS_0141 26 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 148285025 Common tchA hypothetical protein OTBS_1894 2 None None None 148284786 Common spoT31 spoT-like ppGpp hydrolase OTBS_1452 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284946 Common tnE transposase and inactivated derivative OTBS_1739 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148285002 Common folD methylenetetrahydrofolate dehydrogenase OTBS_1842 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 148284502 Pathogen - hypothetical protein OTBS_0893 1 None None None 148284500 Pathogen - hypothetical protein OTBS_0889 1 None None None 148284229 Common recD/traA Helicase RecD/TraA, ATP-dependent exoDNAse (exonuclease V) OTBS_0395 159 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 148284565 Common rho transcription termination factor Rho OTBS_1012 211 COG1158 Rho, Transcription termination factor Transcription 148284699 Common comEC/rec2 ComEC/Rec2 family protein OTBS_1270 168 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 148284847 Common infB translation initiation factor IF-2 OTBS_1568 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 148284746 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A OTBS_1367 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148284936 Pathogen - hypothetical protein OTBS_1720 1 None None None 148284196 Common rplO 50S ribosomal protein L15 OTBS_0358 95 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 148284512 Common groEL heat shock chaperonin protein 60 kD OTBS_0917 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 148284877 Pathogen - hypothetical protein OTBS_1624 1 None None None 148284383 Common fumC fumarate hydratase OTBS_0663 227 COG0114 FumC, Fumarase Energy production and conversion 148284259 Common pcnB polyA polymerase OTBS_0442 206 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 148284567 Common - hypothetical protein OTBS_1016 2 None None None 148284573 Common panF sodium/pantothenate symporter OTBS_1023 163 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148285117 Common traN conjugative transfer protein OTBS_2068 25 None None None 148284709 Common traN conjugative transfer protein OTBS_1291 25 None None None 148284886 Common tlc ADP/ATP carrier protein OTBS_1636 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 148285160 Common rrf ribosome recycling factor OTBS_2158 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 148284807 Common coxC Cytochrome c oxidase subunit III OTBS_1495 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 148284778 Common traB conjugative pilus assembly protein OTBS_1439 24 None None None 148285093 Pathogen rhp9 hypothetical protein OTBS_2020 1 None None None 148284802 Common kgd alpha-ketoglutarate decarboxylase OTBS_1490 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 148284791 Pathogen - hypothetical protein OTBS_1463 1 None None None 148284819 Common traV conjugative transfer protein OTBS_1511 2 None None None 148284082 Common pnp polynucleotide phosphorylase/polyadenylase OTBS_0162 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 148284850 Common - hypothetical protein OTBS_1576 176 COG1496 COG1496, Uncharacterized conserved protein Function unknown 148284840 Common rhp2 hypothetical protein OTBS_1559 2 None None None 148284991 Common trpS tryptophanyl-tRNA synthetase OTBS_1824 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284758 Pathogen - hypothetical protein OTBS_1407 1 None None None 148284224 Common lipA lipoyl synthase OTBS_0390 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 148284729 Common traB conjugative pilus assembly protein OTBS_1334 24 None None None 148284812 Common - Na+/proline symporter/Histidine kinase/Response regualator receivor domain OTBS_1503 223 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148284449 Common cutA Periplasmic divalent cation tolerance protein OTBS_0786 111 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 148285009 Common def peptide deformylase OTBS_1849 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 148284977 Common asd aspartate-semialdehyde dehydrogenase OTBS_1798 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 148284419 Common spoT15 spoT-like ppGpp hydrolase OTBS_0729 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148285054 Common virB6-4 type IV secretion system protein OTBS_1954 14 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 148284536 Common proS prolyl-tRNA synthetase OTBS_0949 235 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284339 Common atpA H(+)-transporting two-sector ATPase F(1) alpha subunit OTBS_0578 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 148284583 Common parA chromosome partitioning protein OTBS_1040 220 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148284142 Common rnd ribonuclease D OTBS_0265 73 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 148284625 Common dprA DNA processing protein OTBS_1123 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 148285110 Common hkp42 putative signal transduction histidine kinase OTBS_2053 16 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284522 Common tnD transposase and inactivated derivative OTBS_0929 94 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284736 Pathogen rhp9 hypothetical protein OTBS_1342 1 None None None 148284967 Common - hypothetical protein OTBS_1780 4 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 148284528 Common traE conjugative transfer protein OTBS_0940 2 None None None 148284463 Common dam8 site-specific DNA adenine methylase OTBS_0817 101 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284735 Pathogen rhp9 hypothetical protein OTBS_1340 1 None None None 148284722 Pathogen - hypothetical protein OTBS_1317 1 None None None 148285159 Common - hypothetical protein OTBS_2157 4 None None None 148284206 Pathogen rpmC 50S ribosomal protein L29 OTBS_0368 1 None None None 148284154 Common coxB cytochrome c oxidase polypeptide II OTBS_0283 149 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 148284669 Common sco2 putative electron transport protein OTBS_1209 104 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 148284834 Common - hypothetical protein OTBS_1541 2 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 148284399 Common pyrH uridylate kinase OTBS_0696 221 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 148284859 Common nusB transcription antitermination protein NusB OTBS_1586 85 COG0781 NusB, Transcription termination factor Transcription 148285080 Common trbC conjugative transfer protein OTBS_1996 9 None None None 148284386 Common grxC glutaredoxin OTBS_0673 125 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 148284179 Common - hypothetical protein OTBS_0337 2 None None None 148284294 Common yqgF Holliday junction resolvase-like protein OTBS_0498 189 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 148284486 Common comF competence protein F OTBS_0857 138 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 148284395 Common lacA ribose-5-phosphate isomerase OTBS_0684 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 148284707 Pathogen - hypothetical protein OTBS_1284 1 None None None 148284620 Pathogen - hypothetical protein OTBS_1110 1 None None None 148284664 Common traB conjugative pilus assembly protein OTBS_1204 22 None None None 148284045 Common traN conjugative transfer protein OTBS_0108 25 None None None 148285066 Pathogen hkp39 putative signal transduction histidine kinase OTBS_1976 2 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284607 Common traB conjugative pilus assembly protein OTBS_1089 24 None None None 148284050 Pathogen - hypothetical protein OTBS_0118 1 None None None 148284342 Common infC translation initiation factor IF-3 OTBS_0582 211 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 148285174 Common - hypothetical protein OTBS_2172 2 None None None 148284768 Common mnhG Multisubunit Na+/H+ antiporter, MnhG subunit OTBS_1421 4 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 148284633 Common tsf Elongation factor EF-Ts OTBS_1139 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 148285169 Common tilS tRNA(Ile)-lysidine synthetase OTBS_2167 202 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 148284895 Common ank2A9 ankyrin repeat protein with 1 ankyrin repeats OTBS_1655 4 None None None 148284870 Pathogen - hypothetical protein OTBS_1611 1 None None None 148284679 Pathogen - hypothetical protein OTBS_1226 1 None None None 148284244 Pathogen rhp7 hypothetical protein OTBS_0414 1 None None None 148284544 Common spoT22 spoT-like ppGpp hydrolase OTBS_0962 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284597 Common hkp24 putative signal transduction histidine kinase OTBS_1073 117 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284427 Common mltE1 putative soluble lytic murein transglycosylase precursor (slt) OTBS_26 144 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148284040 Pathogen rhp6 putative ompA-like autotransporter OTBS_0093 1 None None None 148284772 Common nuoN2 putative monovalent cation/H+ antiporter subunit D OTBS_1425 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148284924 Common rnc ribonuclease III OTBS_1703 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 148285150 Common rluC ribosomal large subunit pseudouridine synthase OTBS_2144 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148284436 Pathogen - hypothetical protein OTBS_0765 1 None None None 148284666 Common traE conjugative transfer protein OTBS_1206 2 None None None 148284670 Pathogen traV conjugative transfer protein OTBS_1210 1 None None None 148284123 Common traN conjugative transfer protein OTBS_0232 25 None None None 148284334 Common gltX glutamyl-tRNA synthetase OTBS_0573 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148284349 Common ftsQ Cell division protein OTBS_0597 70 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 148284555 Common tchA hypothetical protein OTBS_0991 2 None None None 148285162 Common nuoH NADH dehydrogenase I chain H OTBS_2160 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 148284302 Common tchC hypothetical protein OTBS_0512 2 None None None 148284705 Common hkp29 putative signal transduction histidine kinase OTBS_1280 111 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284756 Pathogen - hypothetical protein OTBS_1399 1 None None None 148284130 Common ank1u2 ankyrin repeat protein with 4 ankyrin repeats OTBS_0246 18 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284318 Common rpsR 30S ribosomal protein S18 OTBS_0549 199 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 148284820 Common trbC conjugative transfer protein OTBS_1513 9 None None None 148285015 Common traB conjugative pilus assembly protein OTBS_1870 24 None None None 148284598 Common spoT23 spoT-like ppGpp hydrolase OTBS_1074 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284277 Common mgtE magnesium transporter OTBS_0470 169 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 148285141 Common - hypothetical protein OTBS_2105 2 None None None 148284204 Common rplN 50S ribosomal protein L14 OTBS_0366 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 148284499 Common tchA hypothetical protein OTBS_0885 2 None None None 148284450 Pathogen - hypothetical protein OTBS_0787 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 148285100 Common traV conjugative transfer protein OTBS_2027 2 None None None 148284378 Common tchB hypothetical protein OTBS_0645 2 None None None 148284176 Common corC putative Mg2+ and Co2+ transporter, CBS domain protein OTBS_0332 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 148284002 Common virB10 type IV secretion system protein OTBS_0005 51 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 148284613 Common hscA chaperone protein HscA OTBS_1102 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 148284047 Common traD_F conjugative transfer protein OTBS_0113 45 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284571 Common engA GTP-binding protein EngA OTBS_1021 220 COG1160 COG1160, Predicted GTPases General function prediction only 148284355 Common glyQ glycyl-tRNA synthetase subunit alpha OTBS_0603 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 148285124 Common tchB hypothetical protein OTBS_2077 2 None None None 148284715 Common tnD transposase and inactivated derivative OTBS_1304 86 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284238 Common fabZ (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase OTBS_0404 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 148284644 Common hkp26 putative signal transduction histidine kinase OTBS_1166 2 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284257 Common hupA histone-like DNA-binding protein HU OTBS_0440 191 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148284532 Common - hypothetical protein OTBS_0945 110 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 148284827 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase OTBS_1528 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 148284416 Pathogen - hypothetical protein OTBS_0724 1 None None None 148285032 Common - hypothetical protein OTBS_1911 7 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 148285105 Common tpr1B19 tetratricopeptide repeat protein with 1 trp repeats OTBS_2044 119 COG4105 ComL, DNA uptake lipoprotein General function prediction only 148284880 Common nuoB NADH dehydrogenase subunit B OTBS_1628 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 148284902 Common tpr1B16 tetratricopeptide repeat protein with 8 trp repeats OTBS_1666 155 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284861 Common spoT34 spoT-like ppGpp hydrolase OTBS_1592 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284151 Pathogen - hypothetical protein OTBS_0276 1 None None None 148284249 Pathogen - hypothetical protein OTBS_0426 1 None None None 148284887 Common ruvC Holliday junction resolvase OTBS_1638 187 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 148284446 Common abcT1 putative ABC transporter ATP-binding protein OTBS_0781 243 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148284272 Common ank1B1 ankyrin repeat protein with 5 ankyrin repeats OTBS_0461 61 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284148 Common valS valyl-tRNA synthetase OTBS_0273 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284218 Common recA recombinase A OTBS_0380 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 148284281 Pathogen - hypothetical protein OTBS_0478 1 None None None 148284959 Common secD preprotein translocase subunit SecD OTBS_1761 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 148284656 Common tpr1B13 tetratricopeptide repeat protein with 5 trp repeats OTBS_1187 129 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148285043 Common spoT43 spoT-like ppGpp hydrolase OTBS_1936 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284366 Common spoT12 spoT-like ppGpp hydrolase OTBS_0623 203 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284767 Common - HAD-superfamily subfamily IIA hydrolase OTBS_1420 104 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 148284868 Common ank2A8 ankyrin repeat protein with 1d ankyrin repeats OTBS_1603 4 None None None 148284839 Common spoT33 spoT-like ppGpp synthetase OTBS_1558 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284035 Common traD_Ti conjugative transfer protein OTBS_0087 3 None None None 148285061 Pathogen - hypothetical protein OTBS_1968 1 None None None 148284727 Common trbC conjugative transfer protein OTBS_1331 9 None None None 148284189 Common rpsT 30S ribosomal protein S20 OTBS_0351 104 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 148284654 Common hkp28 putative signal transduction histidine kinase OTBS_1182 111 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284893 Common rpsI 30S ribosomal protein S9 OTBS_1645 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 148284227 Common dapA dihydrodipicolinate synthase OTBS_0393 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148284208 Common rpsC 30S ribosomal protein S3 OTBS_0370 238 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 148284483 Common tdcB threonine dehydratase OTBS_0854 189 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148284070 Pathogen - hypothetical protein OTBS_0149 3 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 148284268 Common era GTP-binding protein Era OTBS_0454 230 COG1159 Era, GTPase General function prediction only 148285078 Common traB conjugative pilus assembly protein OTBS_1993 24 None None None 148284602 Common tnE transposase and inactivated derivative OTBS_1079 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284909 Common ank1B3 ankyrin repeat protein with 5 ankyrin repeats OTBS_1679 61 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284114 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase OTBS_0216 99 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 148285050 Common virB4 type IV secretion system protein OTBS_1950 62 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 148284539 Common gap Glyceraldehyde-3-phosphate dehydrogenase OTBS_0952 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 148284134 Common gyrA DNA gyrase subunit A OTBS_0252 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 148285113 Common - hypothetical protein OTBS_2058 2 None None None 148285071 Pathogen rhp6 putative ompA-like autotransporter OTBS_1982 1 None None None 148284684 Common ank1C10 ankyrin repeat protein with 5 ankyrin repeats OTBS_1241 46 None None None 148284581 Common tatC sec-independent protein translocase protein OTBS_1038 202 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 148284110 Common rplK 50S ribosomal protein L11 OTBS_0212 245 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 148284881 Common nuoC NADH dehydrogenase I chain C OTBS_1629 171 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 148284867 Common dam23 site-specific DNA adenine methylase OTBS_1602 101 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284554 Common traE conjugative transfer protein OTBS_0990 2 None None None 148284964 Common - hypothetical protein OTBS_1771 6 None None None 148284930 Pathogen - hypothetical protein OTBS_1712 1 None None None 148284845 Common yhbC hypothetical protein OTBS_1566 154 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 148284525 Common traV conjugative transfer protein OTBS_0937 2 None None None 148285023 Pathogen rhp7 hypothetical protein OTBS_1892 1 None None None 148284222 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase OTBS_0388 143 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 148285059 Common uvrD DNA helicase II, CAI27690 OTBS_1961 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 148284340 Common atpH H(+)-transporting two-sector ATPase F(1) delta subunit OTBS_0579 55 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 148284860 Common gst glutathione S-transferase OTBS_1589 79 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148284858 Common hisS histidyl-tRNA synthetase OTBS_1585 243 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284871 Pathogen - hypothetical protein OTBS_1613 1 None None None 148284312 Common tchB hypothetical protein OTBS_0530 2 None None None 148284851 Common ccmC heme exporter protein C OTBS_1577 112 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 148284430 Common tnA transposase and inactivated derivative OTBS_0752 22 None None None 148284005 Common rhp2 hypothetical protein OTBS_0009 2 None None None 148284041 Common tchD hypothetical protein OTBS_0096 2 None None None 148284465 Common hkp18 putative signal transduction histidine kinase OTBS_0819 107 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284975 Common gcvT gcvT-like aminomethyltransferase OTBS_1793 62 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 148284992 Pathogen rhp7 hypothetical protein OTBS_1830 1 None None None 148284589 Pathogen rhp6 putative ompA-like autotransporter OTBS_1053 1 None None None 148284104 Common aspS aspartyl-tRNA synthetase OTBS_0206 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284048 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase OTBS_0115 152 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 148284692 Common tchB hypothetical protein OTBS_1258 2 None None None 148284175 Common ubiX 3-octaprenyl-4-hydroxybenzoate carboxy-lyase OTBS_0331 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 148284250 Common rpmJ 50S ribosomal protein L36 OTBS_0427 2 None None None 148284787 Common hkp31 putative signal transduction histidine kinase OTBS_1453 110 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284740 Common - hypothetical protein OTBS_1347 118 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148284920 Common sdhD Succinate dehydrogenase hydrophobic membrane anchor protein OTBS_1697 26 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 148285095 Common int phage-related integrase OTBS_2022 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284409 Pathogen rhp7 hypothetical protein OTBS_0709 1 None None None 148284836 Pathogen - hypothetical protein OTBS_1546 1 None None None 148284076 Common - hypothetical protein OTBS_0155 23 COG5590 COG5590, Uncharacterized conserved protein Function unknown 148285157 Common secB protein-export protein OTBS_2155 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 148284929 Common - hypothetical protein OTBS_1710 107 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 148284388 Common - hypothetical protein OTBS_0675 6 COG5449 COG5449, Uncharacterized conserved protein Function unknown 148284826 Common lipB lipoyltransferase OTBS_1527 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 148285049 Common virB3 type IV secretion system protein OTBS_1949 11 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 148284353 Pathogen - putative Orientia tsutsugamushi type-specific antigen OTBS_0601 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 148284971 Common fusA Elongation factor EF-G OTBS_1784 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 148284570 Common n2B putative ATPase n2B OTBS_1019 92 COG1485 COG1485, Predicted ATPase General function prediction only 148284888 Common duS putative tRNA-dihydrouridine synthase OTBS_1639 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 148284950 Common spoT39 spoT-like ppGpp hydrolase OTBS_1745 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284304 Common ampG1 permease of the major facilitator superfamily OTBS_0516 109 None None None 148284089 Pathogen tchB hypothetical protein OTBS_0181 1 None None None 148285036 Common xseA exodeoxyribonuclease VII large subunit OTBS_1915 203 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 148285166 Common nuoL NADH dehydrogenase I chain L OTBS_2164 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 148284797 Pathogen tchE hypothetical protein OTBS_1480 1 None None None 148285000 Common - hypothetical protein OTBS_1840 24 None None None 148284494 Common trbC conjugative transfer protein OTBS_0879 9 None None None 148284437 Common ppdK pyruvate phosphate dikinase OTBS_0767 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 148285007 Common - hypothetical protein OTBS_1847 5 None None None 148284305 Common traD_Ti conjugative transfer protein OTBS_0519 3 None None None 148284400 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase OTBS_0697 219 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148284515 Pathogen - hypothetical protein OTBS_0920 1 None None None 148284015 Common nrdF ribonucleotide-diphosphate reductase subunit beta OTBS_0027 157 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 148284690 Common traV conjugative transfer protein OTBS_1256 2 None None None 148284017 Common tchB hypothetical protein OTBS_0034 2 None None None 148284780 Common trbC conjugative transfer protein OTBS_1442 9 None None None 148284689 Common traC conjugative transfer protein OTBS_1255 8 None None None 148284677 Common tolQ transport protein OTBS_1223 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 148284060 Pathogen - hypothetical protein OTBS_0139 1 None None None 148284947 Common traD_Ti conjugative transfer protein OTBS_1742 3 None None None 148284720 Common - hypothetical protein OTBS_1312 55 COG0679 COG0679, Predicted permeases General function prediction only 148285072 Pathogen - hypothetical protein OTBS_1984 1 None None None 148285168 Common nuoN NADH dehydrogenase I chain N OTBS_2166 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 148284197 Common rpsE 30S ribosomal protein S5 OTBS_0359 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 148285044 Common rlpA Rare lipoprotein A precursor OTBS_1943 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 148284558 Common cyaY putative iron-binding and oxidizing protein OTBS_0996 4 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 148284397 Common ank1u5 ankyrin repeat protein with 4 ankyrin repeats OTBS_0691 77 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284825 Pathogen - hypothetical protein OTBS_1524 1 None None None 148284663 Common traV conjugative transfer protein OTBS_1203 2 None None None 148284270 Common prfA peptide chain release factor OTBS_0456 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 148285067 Pathogen rhp5 hypothetical protein OTBS_1977 1 None None None 148284579 Common - putative methyltransferase OTBS_1036 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 148284687 Common - hypothetical protein OTBS_1250 47 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 148284095 Pathogen - hypothetical protein OTBS_0193 1 None None None 148284026 Common tchA hypothetical protein OTBS_0063 2 None None None 148284037 Common spoT2 spoT-like ppGpp hydrolase OTBS_0089 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284368 Pathogen rhp4 hypothetical protein OTBS_0627 1 None None None 148284537 Common - hypothetical protein OTBS_0950 2 None None None 148285088 Pathogen hkp41 putative signal transduction histidine kinase OTBS_2011 2 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284866 Pathogen - hypothetical protein OTBS_1601 1 None None None 148284897 Pathogen - hypothetical protein OTBS_1657 1 None None None 148284439 Pathogen - hypothetical protein OTBS_0770 1 None None None 148284719 Pathogen - hypothetical protein OTBS_1311 1 None None None 148284056 Common hkp5 putative signal transduction histidine kinase OTBS_0128 49 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284492 Common traD_F conjugative transfer protein OTBS_0874 45 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284610 Common tchA hypothetical protein OTBS_1092 2 None None None 148284922 Common sdhB succinate dehydrogenase iron-sulfur subunit OTBS_1699 196 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 148284235 Common xerD site-specific tyrosine recombinase XerD OTBS_0401 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284350 Common ddl D-alanine--D-alanine ligase OTBS_0598 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 148284184 Common pgpA phosphatidylglycerophosphatase OTBS_0342 72 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 148285103 Pathogen rhp4 hypothetical protein OTBS_2039 1 None None None 148284615 Common iscA iron-sulfur cluster assembly accessory protein OTBS_1104 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 148284957 Pathogen - hypothetical protein OTBS_1757 1 None None None 148284934 Common ligA NAD-dependent DNA ligase LigA OTBS_1717 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 148285031 Common znuC Zinc ABC transporter ATP-binding protein OTBS_1910 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 148284283 Common spoT8 spoT-like ppGpp hydrolase OTBS_0483 203 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284646 Pathogen rhp4 hypothetical protein OTBS_1168 1 None None None 148284623 Common rpoD RNA polymerase sigma factor OTBS_1120 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148284461 Common - hypothetical protein OTBS_0811 87 COG1565 COG1565, Uncharacterized conserved protein Function unknown 148284703 Pathogen rhp5 hypothetical protein OTBS_1278 1 None None None 148284999 Common pal peptidoglycan-associated lipoprotein precursor OTBS_1839 145 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148284453 Common - hypothetical protein OTBS_0790 2 None None None 148285013 Common tchA hypothetical protein OTBS_1867 2 None None None 148284569 Common tmk thymidylate kinase OTBS_1018 227 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 148284759 Common - Uracil-DNA glycosylase OTBS_1408 152 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148285098 Common tchB hypothetical protein OTBS_2025 2 None None None 148285038 Common - hypothetical protein OTBS_1917 4 None None None 148284187 Common hemA 5-aminolevulinate synthase OTBS_0349 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 148284750 Common - Na+/proline symporter/Histidine kinase/Response regualator receivor domain OTBS_1379 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284846 Common nusA transcription elongation factor NusA OTBS_1567 216 COG0195 NusA, Transcription elongation factor Transcription 148285143 Pathogen rhp2 hypothetical protein OTBS_2107 1 None None None 148285126 Common int phage-related integrase OTBS_2080 189 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284800 Common corB putative Mg2+ and Co2+ transporter, CBS domain protein OTBS_1487 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 148284478 Common icd isocitrate dehydrogenase OTBS_0842 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148284242 Common - hypothetical protein OTBS_0408 9 None None None 148284136 Common - hypothetical protein OTBS_0254 13 COG3164 COG3164, Predicted membrane protein Function unknown 148284485 Common - hypothetical protein OTBS_0856 123 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148284595 Pathogen rhp5 hypothetical protein OTBS_1071 1 None None None 148284125 Common traC conjugative transfer protein OTBS_0236 2 None None None 148284167 Common tlc ATP/ADP translocase OTBS_0313 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 148284211 Common rplB 50S ribosomal protein L2 OTBS_0373 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 148284474 Common tchA hypothetical protein OTBS_0837 2 None None None 148284426 Common - putative aplha/beta hydrolase OTBS_0741 41 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148284126 Pathogen rhp2 hypothetical protein OTBS_0240 2 None None None 148284907 Common tchA hypothetical protein OTBS_1675 2 None None None 148284422 Pathogen rhp6 putative ompA-like autotransporter OTBS_0735 1 None None None 148284635 Common pheS phenylalanyl-tRNA synthetase subunit alpha OTBS_1141 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 148284973 Common tnB transposase and inactivated derivative OTBS_1787 54 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284843 Pathogen - hypothetical protein OTBS_1564 1 None None None 148284994 Common mrp ATP-binding protein OTBS_1834 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148284587 Common tchD hypothetical protein OTBS_1051 2 None None None 148284629 Common ank1F1 ankyrin repeat protein with 8 ankyrin repeats OTBS_1133 101 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284112 Common secE preprotein translocase subunit SecE OTBS_0214 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 148284314 Pathogen - hypothetical protein OTBS_0535 1 None None None 148284873 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase OTBS_1615 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 148284853 Common dsbA Thiol:disulfide interchange protein OTBS_1579 56 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148284725 Common hkp30 putative signal transduction histidine kinase OTBS_1322 27 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284675 Common - hypothetical protein OTBS_1221 8 None None None 148284789 Pathogen rhp5 hypothetical protein OTBS_1457 1 None None None 148284102 Common proP proline/betaine transporter OTBS_0204 115 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 148284694 Common int phage-related integrase OTBS_1261 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284467 Pathogen - hypothetical protein OTBS_0821 1 None None None 148284963 Common - hypothetical protein OTBS_1769 23 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 148284621 Common - putative glycosyl transferase, group 2 OTBS_1111 108 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148284276 Common holA DNA polymerase III subunit delta OTBS_0469 20 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 148284604 Common traN conjugative transfer protein OTBS_1085 25 None None None 148284730 Common tchB hypothetical protein OTBS_1335 2 None None None 148285133 Pathogen - hypothetical protein OTBS_2094 1 None None None 148284116 Common ispZ intracellular septation protein A OTBS_0218 46 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 148284347 Common invA dinucleoside polyphosphate hydrolase OTBS_0590 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 148284391 Common - hypothetical protein OTBS_0678 2 None None None 148285040 Common rpmA 50S ribosomal protein L27 OTBS_1919 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 148284190 Common rplQ 50S ribosomal protein L17 OTBS_0352 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 148284682 Common ssb single-stranded DNA-binding protein OTBS_1237 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 148285063 Pathogen - hypothetical protein OTBS_1972 1 None None None 148284074 Common - hypothetical protein OTBS_0153 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 148284739 Common sucB dihydrolipoamide acetyltransferase component OTBS_1346 181 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148284266 Common rpmF 50S ribosomal protein L32 OTBS_0451 65 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 148285068 Common dam30 site-specific DNA adenine methylase OTBS_1978 99 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284220 Common acpP acyl carrier protein OTBS_0382 39 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148284310 Common traV conjugative transfer protein OTBS_0528 2 None None None 148285115 Common tnE transposase and inactivated derivative OTBS_2062 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284159 Common uvrA excinuclease ABC subunit A OTBS_0292 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 148284556 Pathogen - hypothetical protein OTBS_0993 1 None None None 148284899 Common spoT35 spoT-like ppGpp hydrolase OTBS_1659 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284968 Common radC DNA repair protein OTBS_1781 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 148284856 Common - check-maybe an arthopod gene OTBS_1583 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 148284659 Common tpr1B14 tetratricopeptide repeat protein with 2 trp repeats OTBS_1193 43 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284379 Common tchA hypothetical protein OTBS_0647 2 None None None 148284918 Common int phage-related integrase OTBS_1695 137 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284389 Common - hypothetical protein OTBS_0676 25 COG5448 COG5448, Uncharacterized conserved protein Function unknown 148284263 Common dapB dihydrodipicolinate reductase OTBS_0446 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 148284630 Common pepA leucyl aminopeptidase OTBS_1135 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 148284795 Common traN conjugative transfer protein OTBS_1477 25 None None None 148284247 Common traE conjugative transfer protein OTBS_0417 2 None None None 148284698 Common ntrY NtrY-like histidine kinase OTBS_1269 213 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 148284541 Common - hypothetical protein OTBS_0954 2 None None None 148284932 Common p34 p34 protein/probable cation transporter OTBS_1715 195 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 148285177 Common - hypotheticaal protein OTBS_2175 2 COG1238 COG1238, Predicted membrane protein Function unknown 148284943 Common traV conjugative transfer protein OTBS_1731 2 None None None 148284945 Common traD_F conjugative transfer protein OTBS_1738 40 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148285005 Common mdh malate dehydrogenase, NAD-dependent OTBS_1845 178 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 148284010 Common lpdA dihydrolipoamide dehydrogenase OTBS_0019 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148284147 Common dnaE DNA polymerase III alpha chain OTBS_0272 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 148284307 Common - hypothetical protein OTBS_0523 14 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 148284790 Pathogen rhp6 putative ompA-like autotransporter OTBS_1459 1 None None None 148284080 Common - hypothetical protein OTBS_0160 2 None None None 148284517 Pathogen - hypothetical protein OTBS_0922 1 None None None 148284816 Common traE conjugative transfer protein OTBS_1508 2 None None None 148284507 Common yhbH putative sigma(54) modulation protein OTBS_0906 10 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 148284805 Common proP proline/betaine transporter OTBS_1493 120 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148285087 Common hkp40 putative signal transduction histidine kinase OTBS_2010 117 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284201 Common rpsN 30S ribosomal protein S14 OTBS_0363 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 148284090 Pathogen traV conjugative transfer protein OTBS_0182 1 None None None 148284742 Common map methionine aminopeptidase OTBS_1354 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 148284753 Pathogen - hypothetical protein OTBS_1395 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148284560 Pathogen - hypothetical protein OTBS_1004 2 None None None 148285097 Common traE conjugative transfer protein OTBS_2024 2 None None None 148285021 Pathogen - hypothetical protein OTBS_1887 1 None None None 148284761 Common argB Acetylglutamate kinase OTBS_1414 173 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 148284773 Common nuoL2 NADH dehydrogenase I chain L OTBS_1426 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148284712 Common traW conjugative transfer protein OTBS_1295 26 None None None 148284911 Common - Phage portal protein, HK97 family OTBS_1683 66 COG4695 COG4695, Phage-related protein Function unknown 148284043 Common rhp8 ompA-like, putative autotransporter OTBS_0102 7 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 148284164 Common aprD alkaline protease secretion, ATP-binding protein OTBS_0305 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 148284983 Common ychF putative GTP-binding protein OTBS_1804 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 148284632 Common rpsB 30S ribosomal protein S2 OTBS_1138 216 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 148284459 Common - hypothetical protein OTBS_0806 4 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 148284548 Pathogen - hypothetical protein OTBS_0977 1 None None None 148284069 Common - hypothetical protein OTBS_0148 43 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 148284256 Common - hypothetical protein OTBS_0439 4 None None None 148284412 Common traW conjugative transfer protein OTBS_0715 26 None None None 148284213 Common rplD 50S ribosomal protein L4 OTBS_0375 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 148285035 Common - hypothetical protein OTBS_1914 6 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148284612 Common fdxB ferredoxin-like iron-sulfur cluster-binding protein OTBS_1101 101 COG0633 Fdx, Ferredoxin Energy production and conversion 148284144 Common cdsA phosphatidate cytidylyltransferase OTBS_0267 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 148284710 Common trbC conjugative transfer protein OTBS_1292 9 None None None 148284441 Common - F0F1 ATP synthase subunit C OTBS_0772 13 None None None 148284617 Common iscR iron-sulfur cluster assembly transcription regulation factor OTBS_1107 153 COG1959 COG1959, Predicted transcriptional regulator Transcription 148284286 Common traV conjugative transfer protein OTBS_0488 2 None None None 148285121 Common traV conjugative transfer protein OTBS_2074 2 None None None 148284986 Pathogen rhp6 putative ompA-like autotransporter OTBS_1811 1 None None None 148284763 Common yidC putative inner membrane protein translocase component YidC OTBS_1416 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 148284182 Common thyX FAD-dependent thymidylate synthase OTBS_0340 49 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 148285101 Common trbC conjugative transfer protein OTBS_2029 9 None None None 148284810 Common - hypothetical protein OTBS_1498 4 None None None 148284954 Pathogen rhp6 putative ompA-like autotransporter OTBS_1752 1 None None None 148284031 Common ank1D1 ankyrin repeat protein with 6 ankyrin repeats OTBS_0071 58 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284782 Common traD_F conjugative transfer protein OTBS_1447 40 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148285077 Common tchB hypothetical protein OTBS_1992 2 None None None 148285170 Common ftsH ATP-dependent metalloprotease OTBS_2168 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 148284823 Common ank1A2 ankyrin repeat protein with 8 ankyrin repeats OTBS_1521 68 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284039 Pathogen rhp5 hypothetical protein OTBS_0091 1 None None None 148284245 Common int phage-related integrase OTBS_0415 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284652 Pathogen - hypothetical protein OTBS_1179 1 None None None 148285128 Pathogen ank1C15 ankyrin repeat protein with 2 ankyrin repeats OTBS_2086 1 None None None 148284093 Common hemF coproporphyrinogen III oxidase OTBS_0188 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 148284028 Common traB conjugative pilus assembly protein OTBS_0066 24 None None None 148284172 Common tnD transposase and inactivated derivative OTBS_0322 109 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284661 Common tnD transposase and inactivated derivative OTBS_1197 94 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284511 Common groES heat shock chaperonin protein, 10 kD OTBS_0916 211 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 148285065 Common hkp38 putative signal transduction histidine kinase OTBS_1975 117 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284321 Common msbA1 multidrug resistance protein, ABC-type multidrug transport system, ATPase and permease components OTBS_0552 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148284685 Common greA transcription elongation factor OTBS_1246 202 COG0782 GreA, Transcription elongation factor Transcription 148284351 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase OTBS_0599 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 148284498 Common traE conjugative transfer protein OTBS_0884 2 None None None 148284292 Common mkl ribonucleotide ABC transporter ATP-binding protein OTBS_0496 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 148284021 Common spoT1 spoT-like ppGpp hydrolase OTBS_0040 203 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284476 Pathogen rhp7 hypothetical protein OTBS_0839 1 None None None 148284372 Common traN conjugative transfer protein OTBS_0636 25 None None None 148284101 Common rarD putative permeases-like integral membrane protein OTBS_0203 131 COG2962 RarD, Predicted permeases General function prediction only 148285074 Common int phage-related integrase OTBS_1989 137 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284472 Common traB conjugative pilus assembly protein OTBS_0834 24 None None None 148284592 Common traB conjugative pilus assembly protein OTBS_1067 12 None None None 148284161 Pathogen ank1C2 ankyrin repeat protein with 2 ankyrin repeats OTBS_0298 2 None None None 148285046 Common - hypothetical protein OTBS_1946 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 148284054 Pathogen - hypothetical protein OTBS_0123 2 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 148284576 Common secF preprotein translocase subunit SecF OTBS_1033 220 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 148284402 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase OTBS_0699 208 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 148284432 Common spoT16 spoT-like ppGpp hydrolase OTBS_0755 203 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284195 Common secY preprotein translocase subunit SecY OTBS_0357 218 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 148284420 Common hkp15 putative signal transduction histidine kinase OTBS_0731 16 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284424 Common atpD F0F1 ATP synthase subunit beta OTBS_0738 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 148284776 Common tchA hypothetical protein OTBS_1436 2 None None None 148284299 Pathogen - hypothetical protein OTBS_0505 2 None None None 148284233 Common - hypothetical protein OTBS_0399 3 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 148284336 Common - hypothetical protein OTBS_0575 3 None None None 148284649 Common ank1C8 ankyrin repeat protein with 4 ankyrin repeats OTBS_1172 61 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284455 Pathogen rhp4 hypothetical protein OTBS_0799 1 None None None 148284007 Common trxB1 thioredoxin reductase OTBS_0016 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148284701 Pathogen rhp6 putative ompA-like autotransporter OTBS_1275 1 None None None 148284225 Common sppA Periplasmic serine proteases (ClpP class) OTBS_0391 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148284192 Common rpsK 30S ribosomal protein S11 OTBS_0354 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 148285155 Common trmE tRNA modification GTPase TrmE OTBS_2149 226 COG0486 ThdF, Predicted GTPase General function prediction only 148284262 Pathogen sixA phosphohistidine phosphatase OTBS_0445 1 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 148284822 Common tnE transposase and inactivated derivative OTBS_1519 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284599 Pathogen rhp4 hypothetical protein OTBS_1075 1 None None None 148284019 Common traV conjugative transfer protein OTBS_0036 2 None None None 148284362 Common dam5 site-specific DNA adenine methylase OTBS_0616 68 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148285042 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OTBS_1929 201 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 148284203 Common rplX 50S ribosomal protein L24 OTBS_0365 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 148284133 Common - hypothetical protein OTBS_0251 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 148284803 Common sucB 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase OTBS_1491 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148284458 Common - putative sulfurtransferase OTBS_0805 110 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 148284433 Common tnE transposase and inactivated derivative OTBS_0756 18 None None None 148284706 Common traD_Ti conjugative transfer protein OTBS_1283 3 None None None 148284269 Common - hypothetical protein OTBS_0455 2 None None None 148284814 Common int phage-related integrase OTBS_1506 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284470 Common trbC conjugative transfer protein OTBS_0831 9 None None None 148284771 Common mnhC Multisubunit Na+/H+ antiporter, MnhC subunit OTBS_1424 16 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 148284575 Common - hypothetical protein OTBS_1026 43 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148284590 Pathogen - hypothetical protein OTBS_1059 1 None None None 148284119 Common - conversed hypothetical protein OTBS_0222 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 148284295 Common - hypothetical protein OTBS_0499 2 None None None 148284237 Common surf1 surfeit locus protein 1 OTBS_0403 31 COG3346 COG3346, Uncharacterized conserved protein Function unknown 148284331 Common - hypothetical protein OTBS_0570 2 None None None 148284667 Common tchA hypothetical protein OTBS_1207 2 None None None 148284673 Common gcp O-sialoglycoprotein endopeptidase OTBS_1219 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 148284128 Pathogen rhp5 hypothetical protein OTBS_0244 1 None None None 148284300 Pathogen - hypothetical protein OTBS_0507 1 None None None 148284489 Common - hypothetical protein OTBS_0860 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 148284369 Common traD_Ti conjugative transfer protein OTBS_0628 3 None None None 148284210 Common rpsS 30S ribosomal protein S19 OTBS_0372 239 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 148285026 Common traE conjugative transfer protein OTBS_1895 2 None None None 148285151 Common holB DNA polymerase III subunit delta' OTBS_2145 24 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 148284714 Common tchA hypothetical protein OTBS_1299 2 None None None 148284726 Common traD_Ti conjugative transfer protein OTBS_1325 3 None None None 148285069 Pathogen rhp6 putative ompA-like autotransporter OTBS_1979 1 None None None 148285010 Pathogen rhp6 putative ompA-like autotransporter OTBS_1854 1 None None None 148284838 Common rne Ribonuclease E OTBS_1557 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 148284324 Common htpG heat shock protein 90 OTBS_0556 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 148285084 Common traD_Ti conjugative transfer protein OTBS_2007 3 None None None 148284032 Common tnE transposase and inactivated derivative OTBS_0080 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284443 Pathogen - hypothetical protein OTBS_0774 1 None None None 148284830 Common lysC Aspartate kinase OTBS_1537 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148284927 Common nth Endonuclease III OTBS_1708 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 148284152 Common mccF microcin C7 self-immunity protein OTBS_0277 69 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 148284240 Common radA DNA repair protein RadA OTBS_0406 208 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 148284330 Common tnA transposase and inactivated derivative OTBS_0569 21 None None None 148284985 Common xth1 exodeoxyribonuclease III OTBS_1807 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 148284480 Common proP proline/betaine transporter OTBS_0844 105 None None None 148284282 Pathogen - hypothetical protein OTBS_0480 1 None None None 148285108 Common ank2A12 ankyrin repeat protein with 2 ankyrin repeats OTBS_2051 5 None None None 148284657 Common - hypothetical protein OTBS_1191 22 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 148284393 Common - phage major capsid protein, HK97 OTBS_0680 49 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 148284885 Pathogen - hypothetical protein OTBS_1633 1 None None None 148284099 Common rpmE 50S ribosomal protein L31 OTBS_0201 39 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 148284289 Common rpsD 30S ribosomal protein S4 OTBS_0492 227 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 148284346 Common secA preprotein translocase subunit SecA OTBS_0586 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 148283999 Common dnaN DNA polymerase III subunit beta OTBS_0002 212 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 148284637 Common tchB hypothetical protein OTBS_1151 2 None None None 148285019 Common - hypothetical protein OTBS_1880 26 COG1723 COG1723, Uncharacterized conserved protein Function unknown 148284181 Common virB8 type IV secretion system protein OTBS_0339 5 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 148284149 Common ubiA prenyltransferase OTBS_0274 182 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 148284614 Common hscB co-chaperone protein OTBS_1103 46 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 148284619 Common ftsA cell division protein OTBS_1109 178 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 148284428 Common fabD acyl-carrier-protein S-malonyltransferase OTBS_0743 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 148284320 Common phoB PhoB-like response regulator OTBS_0551 199 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148285123 Common tchC hypothetical protein OTBS_2076 2 None None None 148284325 Common rpmI 50S ribosomal protein L35 OTBS_0557 105 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 148284067 Common pssA CDP-diacylglycerol--serineO-phosphatidyltransferase OTBS_0146 144 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 148284415 Common tpr1B9 tetratricopeptide repeat protein with 8 trp repeats OTBS_0721 155 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284163 Common mviN putative virlence factor, integral membrane protein OTBS_0303 188 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 148285163 Common nuoI NADH dehydrogenase subunit I OTBS_2161 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 148284140 Common rph tRNA nucleotidyltransferase OTBS_0260 181 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 148285145 Pathogen rhp2 hypothetical protein OTBS_2116 1 None None None 148285033 Common dnaX DNA polymerase III subunits gamma and tau OTBS_1912 245 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 148284251 Common trxA thioredoxin OTBS_0434 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148284545 Pathogen rhp4 hypothetical protein OTBS_0963 1 None None None 148284764 Common atrC1 Cationic amino acid transporter-1 OTBS_1417 185 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 148284842 Common ubiB ubiquinone biosynthesis protein, 2-polyprenylphenol 6-hydroxylase OTBS_1563 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 148284271 Pathogen - hypothetical protein OTBS_0457 1 None None None 148284215 Common rpsJ 30S ribosomal protein S10 OTBS_0377 214 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 148284375 Pathogen - hypothetical protein OTBS_0639 1 None None None 148284980 Common - hypothetical protein OTBS_1801 32 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 148284358 Common tnE transposase and inactivated derivative OTBS_0609 18 None None None 148285173 Common rodA rod shape-determining protein rodA OTBS_2171 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148285017 Common trbC conjugative transfer protein OTBS_1873 9 None None None 148284337 Pathogen - hypothetical protein OTBS_0576 1 None None None 148284075 Common ileS isoleucyl-tRNA synthetase OTBS_0154 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284939 Common tchA hypothetical protein OTBS_1727 2 None None None 148285147 Common rhp8 ompA-like, putative autotransporter OTBS_2126 2 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 148284531 Pathogen rhp7 hypothetical protein OTBS_0943 1 None None None 148284087 Common traC conjugative transfer protein OTBS_0174 2 None None None 148284198 Common rplR 50S ribosomal protein L18 OTBS_0360 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 148284801 Common sodB Superoxide dismutase OTBS_1489 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 148284995 Common hflK putative membrane bound protease protein OTBS_1835 169 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148285090 Common dam31 site-specific DNA adenine methylase OTBS_2013 102 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284799 Common ccmF Cytochrome c-type biogenesis OTBS_1486 134 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148284745 Common gatC glutamyl-tRNA(Gln) amidotransferase subunit C OTBS_1366 39 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 148285153 Common dksA DnaK suppressor-like protein OTBS_2147 141 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 148284024 Common ank2A1 ankyrin repeat protein with 1d ankyrin repeats OTBS_0051 2 None None None 148284876 Common rbn putative ribonuclease BN OTBS_1620 61 COG1295 Rbn, Predicted membrane protein Function unknown 148284949 Pathogen - hypothetical protein OTBS_1744 1 None None None 148284191 Common rpoA DNA-directed RNA polymerase alpha chain OTBS_0353 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 148284584 Common parB chromosome partitioning protein OTBS_1041 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 148285060 Common - hypothetical protein OTBS_1967 55 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 148284501 Common traD_Ti conjugative transfer protein OTBS_0892 3 None None None 148284374 Common traU conjugative transfer protein OTBS_0638 26 None None None 148284748 Pathogen - hypothetical protein OTBS_1372 1 None None None 148284831 Common - hypothetical protein OTBS_1538 41 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 148284915 Common ank2A10 ankyrin repeat protein with 4 ankyrin repeats OTBS_1689 3 None None None 148284901 Common traD_Ti conjugative transfer protein OTBS_1663 3 None None None 148284503 Common hkp21 putative signal transduction histidine kinase OTBS_0898 68 None None None 148284508 Common pleC PleC-like histidine kinase OTBS_0907 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284794 Common traD_F conjugative transfer protein OTBS_1473 26 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284120 Common glnQ glutamine ABC transporter ATP-binding protein OTBS_0223 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 148285003 Common - hypothetical protein OTBS_1843 4 None None None 148284382 Common - putative amino acid/peptide transporter OTBS_0662 86 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 148284890 Common ubiG Ubiquinone biosynthesis O-methyltransferase OTBS_1641 154 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 148284639 Common traV conjugative transfer protein OTBS_1153 2 None None None 148284917 Pathogen - hypothetical protein OTBS_1691 2 None None None 148284487 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase OTBS_0858 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 148284606 Common traV conjugative transfer protein OTBS_1088 2 None None None 148284783 Common tnE transposase and inactivated derivative OTBS_1448 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284274 Common - intradiol ring-cleavage dioxygenase OTBS_0467 5 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 148284708 Common traD_F conjugative transfer protein OTBS_1287 44 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284671 Common dnaQ DNA polymerase III epsilon chain OTBS_1217 188 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 148284065 Common coq7 ubiquinone biosynthesis protein OTBS_0144 44 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 148284520 Common tatA twin argininte translocase protein A OTBS_0925 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 148284343 Common thrS threonyl-tRNA synthetase OTBS_0583 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284513 Common acpS 4'-phosphopantetheinyl transferase OTBS_0918 141 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 148284863 Common traD_Ti conjugative transfer protein OTBS_1594 3 None None None 148284650 Common ank1C9 ankyrin repeat protein with 2 ankyrin repeats OTBS_1174 14 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148285171 Common mpg 3-methyladenine DNA glycosylase OTBS_2169 82 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 148284550 Common trbC conjugative transfer protein OTBS_0985 9 None None None 148284547 Pathogen rhp4 hypothetical protein OTBS_0968 1 None None None 148284157 Common - hypothetical protein OTBS_0289 7 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 148284396 Pathogen rhp4 hypothetical protein OTBS_0686 1 None None None 148284978 Common cyoB protoheme IX farnesyltransferase OTBS_1799 180 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 148284523 Common ank1D2 ankyrin repeat protein with 6 ankyrin repeats OTBS_0933 79 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284600 Common traD_Ti conjugative transfer protein OTBS_1076 3 None None None 148284628 Pathogen - hypothetical protein OTBS_1131 1 None None None 148284254 Common rmuC DNA recombination protein OTBS_0437 97 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 148285053 Common virB6-3 type IV secretion system protein OTBS_1953 7 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 148284223 Common - putative oligoketide cyclase/lipid transport protein OTBS_0389 91 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 148284496 Common traB conjugative pilus assembly protein OTBS_0882 24 None None None 148284469 Common traD_F conjugative transfer protein OTBS_0826 44 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284966 Pathogen traW conjugative transfer protein OTBS_1779 1 None None None 148284716 Pathogen - hypothetical protein OTBS_1306 1 None None None 148284529 Common tchA hypothetical protein OTBS_0941 2 None None None 148285102 Common traD_F conjugative transfer protein OTBS_2034 2 None None None 148285178 Common ank1u9 ankyrin repeat protein with 8 ankyrin repeats OTBS_2178 64 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284734 Pathogen rhp7 hypothetical protein OTBS_1339 1 None None None 148284315 Common bcp bacterioferritin comigratory protein OTBS_0544 217 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148285132 Common ank1C16 ankyrin repeat protein with 1 ankyrin repeats OTBS_2093 4 None None None 148284044 Common tpr1B1 tetratricopeptide repeat protein with 2 trp repeats OTBS_0106 25 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284640 Common trbC conjugative transfer protein OTBS_1155 9 None None None 148284696 Common - hypothetical protein OTBS_1267 53 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 148284413 Pathogen tchE hypothetical protein OTBS_0716 1 None None None 148284288 Common tchB hypothetical protein OTBS_0490 2 None None None 148284232 Common - hypothetical protein OTBS_0398 4 None None None 148284754 Common petA Ubiquinol-cytochrome c reductase, iron-sulfur subunit OTBS_1396 111 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 148284448 Common ffh signal recognition particle protein OTBS_0785 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 148284264 Common yqiX amino acid ABC transporter substrate binding protein OTBS_0447 150 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148284108 Common rplJ 50S ribosomal protein L10 OTBS_0210 195 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 148284952 Pathogen - hypothetical protein OTBS_1749 1 None None None 148284293 Common recJ single-stranded-DNA-specific exonuclease OTBS_0497 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 148284407 Common bolA BolA-like putative stress-induced morphogen OTBS_0705 64 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 148284665 Common tchB hypothetical protein OTBS_1205 2 None None None 148284333 Common iscA iron-binding protein IscA/HesB OTBS_0572 161 COG0316 IscA, Uncharacterized conserved protein Function unknown 148284479 Common hemC porphobilinogen deaminase OTBS_0843 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 148284150 Pathogen - hypothetical protein OTBS_0275 1 None None None 148285142 Pathogen - hypothetical protein OTBS_2106 1 None None None 148284596 Pathogen hkp23 putative signal transduction histidine kinase OTBS_1072 2 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148285014 Common tchB hypothetical protein OTBS_1869 2 None None None 148284230 Common rplS 50S ribosomal protein L19 OTBS_0396 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 148284435 Common trpS tryptophanyl-tRNA synthetase OTBS_0762 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284417 Common - hypothetical protein OTBS_0726 2 None None None 148284122 Common - hypothetical protein OTBS_0227 2 None None None 148284451 Common gmpk guanylate kinase OTBS_0788 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 148285057 Common gltX glutamyl-tRNA synthetase OTBS_1957 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148284094 Common - hypothetical protein OTBS_0189 6 None None None 148284410 Common tchA hypothetical protein OTBS_0711 2 None None None 148284828 Common ftsW cell division protein OTBS_1529 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148284205 Common rpsQ 30S ribosomal protein S17 OTBS_0367 228 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 148284364 Common hkp11 putative signal transduction histidine kinase OTBS_0620 114 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284301 Common traE conjugative transfer protein OTBS_0511 2 None None None 148284757 Pathogen rhp2 hypothetical protein OTBS_1402 2 None None None 148284704 Pathogen - hypothetical protein OTBS_1279 1 None None None 148284821 Common traD_F conjugative transfer protein OTBS_1518 44 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284460 Pathogen - hypothetical protein OTBS_0809 1 None None None 148284131 Common infA translation initiation factor IF-1 OTBS_0249 211 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 148284518 Pathogen - hypothetical protein OTBS_0923 1 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 148284655 Common tnD transposase and inactivated derivative OTBS_1185 109 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148285039 Common rplU 50S ribosomal protein L21 OTBS_1918 207 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 148284217 Common spoU tRNA/rRNA methyltransferase OTBS_0379 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 148284616 Common iscU FeS cluster assembly scaffold protein OTBS_1105 123 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 148284053 Pathogen tpr1A2 tetratricopeptide repeat protein with 1 trp repeats OTBS_0121 1 None None None 148284543 Common hkp22 putative signal transduction histidine kinase OTBS_0961 110 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148285125 Common tchA hypothetical protein OTBS_2079 2 None None None 148285106 Pathogen - hypothetical protein OTBS_2045 1 None None None 148284892 Common rplM 50S ribosomal protein L13 OTBS_1644 216 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 148284377 Common tchC hypothetical protein OTBS_0644 2 None None None 148284003 Common virB11 type IV secretion system protein OTBS_0006 153 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 148285161 Common nuoG NADH dehydrogenase subunit G OTBS_2159 189 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 148284177 Common - hypothetical protein OTBS_0333 114 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 148284370 Common tnE transposase and inactivated derivative OTBS_0630 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 148284212 Common rplW 50S ribosomal protein L23 OTBS_0374 157 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 148284356 Common glyS glycyl-tRNA synthetase subunit beta OTBS_0604 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 148284327 Pathogen - hypothetical protein OTBS_0563 1 None None None 148285175 Common pbpA1 Penicillin-binding protein OTBS_2173 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148284766 Common gyrB DNA gyrase subunit B OTBS_1419 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 148284046 Common tpr1B2 tetratricopeptide repeat protein with 5 trp repeats OTBS_0112 129 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284365 Common hkp12 putative signal transduction histidine kinase OTBS_0621 84 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284869 Common - Mg chelatase-related protein OTBS_1607 200 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 148285140 Common tnA transposase and inactivated derivative OTBS_2103 22 None None None 148284533 Common - hypothetical protein OTBS_0946 2 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148284034 Common ank1u1 ankyrin repeat protein with 14 ankyrin repeats OTBS_0084 25 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284186 Common perM putative permease protein OTBS_0348 118 COG0628 PerM, Predicted permease General function prediction only 148284078 Common holC DNA polymerase III chi subunit OTBS_0157 22 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 148284988 Common cycC cytochrome c OTBS_1817 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 148284634 Common pheT phenylalanyl-tRNA synthetase subunit beta OTBS_1140 244 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 148284390 Common - hypothetical protein OTBS_0677 2 None None None 148284903 Common trbC conjugative transfer protein OTBS_1669 9 None None None 148284243 Common - hypothetical protein OTBS_0409 8 None None None 148284862 Pathogen rhp4 hypothetical protein OTBS_1593 1 None None None 148284097 Common - hypothetical protein OTBS_0199 81 COG2835 COG2835, Uncharacterized conserved protein Function unknown 148285079 Common traV conjugative transfer protein OTBS_1994 2 None None None 148284647 Pathogen - hypothetical protein OTBS_1169 1 None None None 148284445 Pathogen - hypothetical protein OTBS_0780 1 None None None 148284925 Common aas acylglycerophosphoethanolamine acyltransferase OTBS_1706 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148285001 Common trxB2 Thioredoxin reductase OTBS_1841 236 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148284505 Pathogen rhp6 putative ompA-like autotransporter OTBS_0901 1 None None None 148285092 Common tchD hypothetical protein OTBS_2015 2 None None None 148284085 Common - putative transcriptional regulator OTBS_0168 41 COG1396 HipB, Predicted transcriptional regulators Transcription 148284792 Common - hypothetical protein OTBS_1467 74 COG1520 COG1520, FOG: WD40-like repeat Function unknown 148284001 Common virB9 type IV secretion system protein OTBS_0004 34 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 148284913 Common - putative transcriptional regulator OTBS_1685 38 COG1396 HipB, Predicted transcriptional regulators Transcription 148284058 Pathogen - hypothetical protein OTBS_0137 1 None None None 148284642 Common tnD transposase and inactivated derivative OTBS_1163 109 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284833 Common ygfA 5-Formyltetrahydrofolate cyclo-ligase OTBS_1540 109 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 148284105 Common rpoC DNA-directed RNA polymerase beta prime chain OTBS_0207 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 148284188 Common ptrB protease II OTBS_0350 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 148284063 Common lysK lysyl-tRNA synthetase OTBS_0142 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 148284384 Pathogen - hypothetical protein OTBS_0664 2 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 148285118 Common trbC conjugative transfer protein OTBS_2069 9 None None None 148284785 Pathogen rhp4 hypothetical protein OTBS_1451 1 None None None 148285083 Pathogen - hypothetical protein OTBS_2006 1 None None None 148284138 Pathogen rpmH 50S ribosomal protein L34 OTBS_0257 1 None None None 148284572 Common polA DNA polymerase I OTBS_1022 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 148284777 Common tchB hypothetical protein OTBS_1438 2 None None None 148284691 Common traB conjugative pilus assembly protein OTBS_1257 24 None None None 148284562 Common - hypothetical protein OTBS_1008 97 COG1981 COG1981, Predicted membrane protein Function unknown 148284012 Pathogen - hypothetical protein OTBS_0021 1 None None None 148284937 Common hkp35 putative signal transduction histidine kinase OTBS_1723 84 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284645 Common dam12 site-specific DNA adenine methylase OTBS_1167 7 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284747 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B OTBS_1368 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 148284878 Pathogen - hypothetical protein OTBS_1626 1 None None None 148284582 Common gidB glucose-inhibited division protein B OTBS_1039 188 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 148284626 Common tdpX1 thioredoxin peroxidase 1 OTBS_1124 223 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148284169 Common ispB octaprenyl-diphosphate synthase OTBS_0315 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148285024 Common int phage-related integrase OTBS_1893 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284976 Common pkcI protein kinase C inhibitor 1 OTBS_1797 220 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 148285135 Pathogen - hypothetical protein OTBS_2097 1 None None None 148284493 Common traN conjugative transfer protein OTBS_0878 25 None None None 148284143 Common - hypothetical protein OTBS_0266 7 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 148284464 Pathogen hkp46 putative signal transduction histidine kinase OTBS_0818 1 None None None 148285109 Pathogen - hypothetical protein OTBS_2052 2 None None None 148284958 Common yajC preprotein translocase subunit YajC OTBS_1760 124 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 148284171 Pathogen tchE hypothetical protein OTBS_0318 1 None None None 148284737 Common mreC rod shape-determining protein OTBS_1344 138 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 148284990 Pathogen ank1C13 ankyrin repeat protein with 1 ankyrin repeats OTBS_1823 1 None None None 148284678 Common hemB delta-aminolevulinic acid dehydratase OTBS_1224 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 148285130 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OTBS_2088 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 148284106 Common rpoB DNA-directed RNA polymerase subunit beta OTBS_0208 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 148284303 Common panF sodium/pantothenate symporter OTBS_0515 62 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148284718 Common miaB MiaB-like tRNA modifying enzyme OTBS_1308 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148284317 Common rplI 50S ribosomal protein L9 OTBS_0548 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 148284813 Pathogen rhp7 hypothetical protein OTBS_1505 1 None None None 148285055 Common proP proline/betaine transporter OTBS_1955 119 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 148284728 Common traV conjugative transfer protein OTBS_1333 2 None None None 148285081 Common tpr1B18 tetratricopeptide repeat protein with 9 trp repeats OTBS_2002 153 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284905 Common tchB hypothetical protein OTBS_1673 2 None None None 148284535 Common clpX ATP-dependent protease ATP-binding subunit OTBS_0948 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 148284997 Common htrA periplasmic serine protease OTBS_1837 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 148284552 Common traB conjugative pilus assembly protein OTBS_0988 24 None None None 148284073 Common ubiH 2-polyprenyl-6-methoxyphenol 4-hydroxylase OTBS_0152 114 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 148285008 Common fmt methionyl-tRNA formyltransferase OTBS_1848 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 148284608 Common tchB hypothetical protein OTBS_1090 2 None None None 148284051 Common tnD transposase and inactivated derivative OTBS_0119 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284221 Common fabF 3-oxoacyl-[acyl carrier protein] synthase II OTBS_0383 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148284841 Common - hypothetical protein OTBS_1561 2 None None None 148284341 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase OTBS_0580 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 148285029 Common tchA hypothetical protein OTBS_1904 2 None None None 148284155 Common - hypothetical protein OTBS_0284 19 COG1714 COG1714, Predicted membrane protein/domain Function unknown 148284178 Common ftsY cell division ABC transporter, periplasmic substrate-binding protein OTBS_0336 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 148284896 Common dam25 site-specific DNA adenine methylase OTBS_1656 101 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148285111 Common spoT47 spoT-like ppGpp hydrolase OTBS_2055 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284848 Common rbfA ribosome-binding factor A OTBS_1569 16 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 148284398 Common abcT3 multidrug resistance ABC transporter ATP-binding protein OTBS_0695 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148284036 Pathogen rhp4 hypothetical protein OTBS_0088 1 None None None 148284027 Common tchB hypothetical protein OTBS_0065 2 None None None 148284411 Common dam6 site-specific DNA adenine methylase OTBS_0713 2 None None None 148285064 Common spoT44 spoT-like ppGpp hydrolase OTBS_1974 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284688 Pathogen - hypothetical protein OTBS_1251 1 None None None 148285104 Common lspA lipoprotein signal peptidase OTBS_2043 143 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148284367 Common tnE transposase and inactivated derivative OTBS_0624 18 None None None 148285073 Pathogen rhp7 hypothetical protein OTBS_1988 1 None None None 148284781 Common traF conjugative pilus assembly protein OTBS_1444 13 None None None 148284721 Common maeA NADP-dependent malic enzyme OTBS_1313 188 COG0281 SfcA, Malic enzyme Energy production and conversion 148284923 Common lepB signal peptidase I OTBS_1702 197 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 148284077 Common rpsU 30S ribosomal protein S21 OTBS_0156 37 None None None 148285045 Common - putative mechanosensitive ion channel OTBS_1945 80 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148284020 Common tnE transposase and inactivated derivative OTBS_0039 18 None None None 148284549 Common - hypothetical protein OTBS_0978 2 None None None 148284329 Common rpmG 50S ribosomal protein L33 OTBS_0565 103 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 148284662 Common trbC conjugative transfer protein OTBS_1201 9 None None None 148284219 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase OTBS_0381 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148285127 Common spoT48 spoT-like ppGpp hydrolase OTBS_2085 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284185 Pathogen rhp4 hypothetical protein OTBS_0346 1 None None None 148284618 Common - hypothetical protein OTBS_1108 78 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 148284760 Common int phage-related integrase OTBS_1410 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284956 Common ank1u8 ankyrin repeat protein with 12 ankyrin repeats OTBS_1755 110 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284145 Common uppS undecaprenyl pyrophosphate synthetase OTBS_0268 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 148285030 Common znuB Zinc/manganese ABC transporter permease protein OTBS_1909 126 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148284354 Pathogen - putative Orientia tsutsugamushi type-specific antigen OTBS_0602 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 148284769 Common mbhE Multisubunit Na+/H+ antiporter, membrane bound hydrogenase, MbhE subunit OTBS_1422 19 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 148284811 Common bcr drug resistance transporter, Bcr/CflA family OTBS_1499 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148285144 Common xth1 exodeoxyribonuclease III OTBS_2114 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 148285167 Common nuoM NADH dehydrogenase subunit M OTBS_2165 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 148284491 Common ank2A5 ankyrin repeat protein with 1d ankyrin repeats OTBS_0871 3 None None None 148284214 Common rplC 50S ribosomal protein L3 OTBS_0376 218 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 148284236 Common traF conjugative pilus assembly protein OTBS_0402 2 None None None 148285012 Common ndk nucleoside diphosphate kinase OTBS_1862 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 148284702 Pathogen - hypothetical protein OTBS_1277 1 None None None 148284818 Common traB conjugative pilus assembly protein OTBS_1510 14 None None None 148284194 Common adk Adenylate kinase OTBS_0356 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 148284092 Common miaB MiaB-like tRNA modifying enzyme OTBS_0187 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148284751 Common ccmA heme exporter protein A OTBS_1392 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 148285156 Common - NAD-glutamate dehydrogenase OTBS_2150 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 148284808 Common ruvB Holliday junction DNA helicase B OTBS_1496 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 148284636 Common tchA hypothetical protein OTBS_1149 2 None None None 148285099 Common traB conjugative pilus assembly protein OTBS_2026 24 None None None 148284462 Common ank2A4 ankyrin repeat protein with 1 ankyrin repeats OTBS_0816 5 None None None 148284241 Common rarD putative permeases-like integral membrane protein OTBS_0407 59 None None None 148284775 Common ank2A7 ankyrin repeat protein with 1 ankyrin repeats OTBS_1433 3 None None None 148284454 Common traD_Ti conjugative transfer protein OTBS_0798 3 None None None 148285119 Pathogen tchE hypothetical protein OTBS_2071 1 None None None 148284421 Common - hypothetical protein OTBS_0732 2 None None None 148285112 Pathogen rhp4 hypothetical protein OTBS_2056 1 None None None 148284348 Common recF recombination protein F OTBS_0596 157 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 148284425 Common - Glycosyltransferase OTBS_0740 184 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148284059 Common - hypothetical protein OTBS_0138 62 None None None 148284006 Pathogen - hypothetical protein OTBS_0012 1 None None None 148284258 Common znuA zinc/manganese ABC transporter substrate binding protein OTBS_0441 18 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 148284524 Common trbC conjugative transfer protein OTBS_0935 9 None None None 148284477 Common - Na+/proline symporter/Histidine kinase/Response regualator receivor domain OTBS_0841 227 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148284593 Common tnB transposase and inactivated derivative OTBS_1069 56 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 148284124 Common trbC conjugative transfer protein OTBS_0233 9 None None None 148284594 Common dam11 site-specific DNA adenine methylase OTBS_1070 101 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284403 Common pbpA2 penicillin-binding protein OTBS_0700 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148285070 Common ank1C14 ankyrin repeat protein with 6 ankyrin repeats OTBS_1980 71 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284473 Common tchB hypothetical protein OTBS_0835 2 None None None 148284135 Common glyA glycine/serine hydroxymethyltransferase OTBS_0253 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 148284857 Common - putative ABC transporter substrate binding protein OTBS_1584 102 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 148284385 Common - hypothetical protein OTBS_0671 18 None None None 148284683 Pathogen - hypothetical protein OTBS_1239 1 None None None 148284158 Common tpr1B4 tetratricopeptide repeat protein with 2 trp repeats OTBS_0290 40 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284111 Common nusG transcription antitermination protein OTBS_0213 214 COG0250 NusG, Transcription antiterminator Transcription 148285114 Pathogen - hypothetical protein OTBS_2060 1 None None None 148284889 Common - hypothetical protein OTBS_1640 2 COG1872 COG1872, Uncharacterized conserved protein Function unknown 148284693 Common tchA hypothetical protein OTBS_1260 2 None None None 148284965 Common recO DNA repair protein RecO OTBS_1772 38 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 148284882 Common nuoD NADH dehydrogenase subunit D OTBS_1630 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 148284564 Common hemE uroporphyrinogen decarboxylase OTBS_1010 180 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 148284484 Common lon ATP-dependent protease La OTBS_0855 208 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 148284401 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase OTBS_0698 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 148285136 Pathogen rhp4 hypothetical protein OTBS_2098 1 None None None 148284894 Pathogen - hypothetical protein OTBS_1646 1 None None None 148284908 Common int phage-related integrase OTBS_1676 131 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284609 Common traE conjugative transfer protein OTBS_1091 2 None None None 148284566 Pathogen - hypothetical protein OTBS_1014 1 None None None 148284601 Pathogen - hypothetical protein OTBS_1077 1 None None None 148284738 Common mreB rod shape-determining protein OTBS_1345 232 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 148284452 Pathogen - hypothetical protein OTBS_0789 1 None None None 148284872 Common ftsZ cell division protein ftsZ OTBS_1614 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 148284115 Common recR recombination protein RecR OTBS_0217 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 148284392 Common - hypothetical protein OTBS_0679 3 None None None 148284049 Pathogen - hypothetical protein OTBS_0116 1 None None None 148284174 Common pleD response regulator PleD OTBS_0330 223 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 148284166 Common tlc ATP/ADP translocase OTBS_0312 7 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 148284466 Common spoT19 spoT-like ppGpp hydrolase OTBS_0820 204 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284418 Pathogen rhp4 hypothetical protein OTBS_0728 1 None None None 148284962 Common vacJ VacJ-like lipoprotein OTBS_1768 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 148285022 Common bcr drug resistance transporter, Bcr/CflA family OTBS_1891 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148284931 Pathogen - hypothetical protein OTBS_1714 2 None None None 148284788 Pathogen - hypothetical protein OTBS_1456 1 None None None 148284311 Common traB conjugative pilus assembly protein OTBS_0529 24 None None None 148284083 Common rpsO 30S ribosomal protein S15 OTBS_0163 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 148284228 Common ilvE branched-chain amino acid aminotransferase OTBS_0394 213 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 148284284 Common tnE transposase and inactivated derivative OTBS_0484 18 None None None 148284004 Common virD4 type IV secretion system protein OTBS_0007 73 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148284624 Common dnaG DNA primase OTBS_1121 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 148284770 Common mnhB Multisubunit Na+/H+ antiporter, MnhB subunit OTBS_1423 33 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 148284974 Common cspA Cold shock-like protein OTBS_1788 36 COG1278 CspC, Cold shock proteins Transcription 148284852 Common fdxA Ferredoxin OTBS_1578 172 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 148284998 Pathogen - hypothetical protein OTBS_1838 1 None None None 148284267 Common smpA putative outer membrane lipoprotein OTBS_0452 2 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 148284260 Common gltP putative proton/glutamate symporter OTBS_0443 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 148284538 Common - phosphoglycerate kinase OTBS_0951 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 148284676 Common tolR transport protein OTBS_1222 142 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 148284580 Common serS seryl-tRNA synthetase OTBS_1037 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284879 Common nuoA NADH dehydrogenase subunit A OTBS_1627 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 148285051 Common virB6-1 type IV secretion system protein OTBS_1951 6 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 148284935 Common - aminopeptidase OTBS_1718 198 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 148284557 Common - putative export ATP-binding/permease protein OTBS_0995 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148284970 Common rpsG 30S ribosomal protein S7 OTBS_1783 220 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 148284278 Common - Zn-dependent carboxypeptidase OTBS_0471 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 148284088 Common tyrS tyrosyl-tRNA synthetase OTBS_0179 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148285094 Pathogen rhp7 hypothetical protein OTBS_2021 1 None None None 148284741 Common clpP ATP-dependent protease proteolytic subunit OTBS_1350 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148284207 Common rplP 50S ribosomal protein L16 OTBS_0369 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 148284514 Common spoT21 spoT-like bifunctional ppGpp synthetase/hydrolase OTBS_0919 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284079 Common proP proline/betaine transporter OTBS_0158 99 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148284578 Common tlc ATP/ADP translocase OTBS_1035 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 148285056 Common mutL DNA mismatch repair protein OTBS_1956 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 148285086 Common spoT45 spoT-like ppGpp hydrolase OTBS_2009 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284928 Common grlA glutaredoxin-related protein OTBS_1709 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 148284989 Common hflC putative membrane protease, stomatin/prohibitin-like protein OTBS_1818 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148284016 Common tchA hypothetical protein OTBS_0032 2 None None None 148285006 Common rimM 16S rRNA-processing protein OTBS_1846 94 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 148284942 Common traB conjugative pilus assembly protein OTBS_1730 24 None None None 148284438 Common - hypothetical protein OTBS_0769 59 COG1738 COG1738, Uncharacterized conserved protein Function unknown 148284559 Common - hypothetical protein OTBS_0999 12 None None None 148284835 Pathogen - hypothetical protein OTBS_1545 1 None None None 148284542 Common ank1u6 ankyrin repeat protein with 5 ankyrin repeats OTBS_0959 79 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284798 Common traW conjugative transfer protein OTBS_1481 26 None None None 148284306 Pathogen rhp4 hypothetical protein OTBS_0520 1 None None None 148284328 Common rpsP 30S ribosomal protein S16 OTBS_0564 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 148285048 Common priA primosome assembly protein PriA OTBS_1948 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 148284723 Common dam17 site-specific DNA adenine methylase OTBS_1318 97 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284944 Common trbC conjugative transfer protein OTBS_1733 9 None None None 148285176 Common ubiD 3-polyprenyl-4-hydroxybenzoate decarboxylase OTBS_2174 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 148284910 Pathogen - hypothetical protein OTBS_1682 1 None None None 148284014 Common nrdA ribonucleotide-diphosphate reductase subunit alpha OTBS_0026 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 148284406 Common dnaK chaperone protein OTBS_0704 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 148284504 Pathogen - hypothetical protein OTBS_0899 1 None None None 148284951 Common hkp37 putative signal transduction histidine kinase OTBS_1746 110 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284061 Common tpiA triosephosphate isomerase OTBS_0140 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 148285158 Common dcd deoxycytidine triphosphate deaminase OTBS_2156 150 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 148284103 Common pbpE Penicillin-binding protein 4* OTBS_0205 128 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 148285139 Common hkp45 putative signal transduction histidine kinase OTBS_2101 111 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284335 Common alaS alanyl-tRNA synthetase OTBS_0574 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284216 Common tuf elongation factor Tu OTBS_0378 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 148285120 Common traW conjugative transfer protein OTBS_2072 26 None None None 148284497 Common tchB hypothetical protein OTBS_0883 2 None None None 148285149 Pathogen - hypothetical protein OTBS_2143 1 None None None 148284982 Common pth peptidyl-tRNA hydrolase OTBS_1803 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 148284352 Common murC UDP-N-acetylmuramate--L-alanine ligase OTBS_0600 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 148284898 Common hkp33 putative signal transduction histidine kinase OTBS_1658 107 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284183 Common cinA putative competence/damaged related protein OTBS_0341 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 148285089 Common ank2A11 ankyrin repeat protein with 1 ankyrin repeats OTBS_2012 5 None None None 148285076 Common traE conjugative transfer protein OTBS_1991 2 None None None 148284234 Common tolC outer membrane efflux protein OTBS_0400 60 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148284068 Common mnhE multisubunit Na+/H+ antiporter, MnhE subunit OTBS_0147 17 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 148285165 Common nuoK NADH dehydrogenase I chain K OTBS_2163 162 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 148284711 Pathogen tchE hypothetical protein OTBS_1294 1 None None None 148284255 Common ksgA dimethyladenosine transferase OTBS_0438 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 148284686 Common rpoH RNA polymerase factor sigma-32 OTBS_1247 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148284322 Common tig FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) OTBS_0554 198 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 148284038 Common hkp3 putative signal transduction histidine kinase OTBS_0090 109 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284173 Common apaG ApaG OTBS_0329 88 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 148284651 Common spoT26 spoT-like ppGpp hydrolase OTBS_1175 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284987 Pathogen - hypothetical protein OTBS_1815 1 None None None 148284285 Common ank1u4 ankyrin repeat protein with 3 ankyrin repeats OTBS_0486 84 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284165 Common aprE alkaline protease secretion protein OTBS_0306 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148284030 Common trbC conjugative transfer protein OTBS_0069 6 None None None 148284921 Common sdhA succinate dehydrogenase flavoprotein subunit OTBS_1698 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 148284359 Common spoT11 spoT-like ppGpp hydrolase OTBS_0613 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284029 Common traV conjugative transfer protein OTBS_0067 2 None None None 148284762 Common uvrA Hypothetical GTP-binding protein OTBS_1415 176 COG0218 COG0218, Predicted GTPase General function prediction only 148284482 Common rhp2 hypothetical protein OTBS_0852 3 None None None 148284057 Pathogen - hypothetical protein OTBS_0135 1 None None None 148285075 Common tchA hypothetical protein OTBS_1990 2 None None None 148284298 Common tchA hypothetical protein OTBS_0502 2 None None None 148284865 Pathogen rhp5 hypothetical protein OTBS_1600 1 None None None 148284641 Common tpr1B12 tetratricopeptide repeat protein with 5 trp repeats OTBS_1161 129 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284423 Common atpC ATP synthase epsilon chain OTBS_0737 39 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 148284488 Common rnhB ribonuclease HII OTBS_0859 227 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 148284588 Common ank1C7 ankyrin repeat protein with 6 ankyrin repeats OTBS_1052 63 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148284475 Common int phage-related integrase OTBS_0838 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284405 Common dnaJ chaperone protein OTBS_0703 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 148284591 Pathogen traV conjugative transfer protein OTBS_1066 1 None None None 148284471 Common traV conjugative transfer protein OTBS_0833 2 None None None 148284239 Common - putative methylase OTBS_0405 199 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 148284371 Common tpr1B8 tetratricopeptide repeat protein with 5 trp repeats OTBS_0632 129 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284440 Common - F0F1 ATP synthase subunit A OTBS_0771 191 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 148284160 Common tnE transposase and inactivated derivative OTBS_0295 18 None None None 148284273 Common gppA phosphotase, Ppx/GppA family, sugar kinase/actin/hsp70 superfamily OTBS_0465 99 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 148284127 Common hkp6 putative signal transduction histidine kinase OTBS_0243 101 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284431 Common hkp16 putative signal transduction histidine kinase OTBS_0753 27 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284700 Pathogen - hypothetical protein OTBS_1271 1 None None None 148285154 Common xerC site-specific tyrosine recombinase XerC OTBS_2148 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148284193 Common rpsM 30S ribosomal protein S13 OTBS_0355 233 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 148284291 Common - ABC transporter permease protein OTBS_0495 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 148284456 Common spoT18 spoT-like ppGpp hydrolase OTBS_0800 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148284577 Common mutS DNA mismatch repair protein OTBS_1034 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148284724 Pathogen rhp6 putative ompA-like autotransporter OTBS_1319 1 None None None 148284008 Common - hypothetical protein OTBS_0017 66 COG0679 COG0679, Predicted permeases General function prediction only 148284022 Pathogen rhp2 hypothetical protein OTBS_0047 2 None None None 148284648 Pathogen rhp6 putative ompA-like autotransporter OTBS_1171 1 None None None 148284855 Common rnhA ribonuclease H OTBS_1582 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 148284844 Common ubiE ubiquinone/menaquinone biosynthesis methlytransferase OTBS_1565 210 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148284603 Common tpr1B11 tetratricopeptide repeat protein with 5 trp repeats OTBS_1081 129 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284972 Common rpsA 30S ribosomal protein S1 OTBS_1785 213 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 148285020 Common coxW cytochrome c oxidase assembly protein OTBS_1883 43 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 148284732 Common tchA hypothetical protein OTBS_1337 2 None None None 148284731 Common traE conjugative transfer protein OTBS_1336 2 None None None 148284854 Common - hypothetical protein OTBS_1581 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 148284993 Pathogen - hypothetical protein OTBS_1832 1 None None None 148284113 Common tuf elongation factor Tu OTBS_0215 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 148284313 Common tchA hypothetical protein OTBS_0532 2 None None None 148284226 Common smpB SsrA-binding protein OTBS_0392 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 148284622 Pathogen - hypothetical protein OTBS_1112 1 None None None 148285137 Common dam34 site-specific DNA adenine methylase OTBS_2099 7 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148285134 Pathogen rhp6 putative ompA-like autotransporter OTBS_2095 1 None None None 148285062 Pathogen - hypothetical protein OTBS_1971 1 None None None 148284100 Common rpmB 50S ribosomal protein L28 OTBS_0202 110 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 148284568 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA OTBS_1017 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 148285116 Common tpr1B20 tetratricopeptide repeat proteinFT with 5 trp repeats OTBS_2064 129 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148284969 Common rpsL 30S ribosomal protein S12 OTBS_1782 244 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 148284137 Pathogen rnpA ribonuclease P protein OTBS_0256 1 None None None 148285058 Common cysS cysteinyl-tRNA synthetase OTBS_1958 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284275 Common leuS leucyl-tRNA synthetase OTBS_0468 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284681 Common - hypothetical protein OTBS_1236 11 None None None 148284653 Common hkp27 putative signal transduction histidine kinase OTBS_1181 2 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148284660 Common ank1u7 ankyrin repeat protein with 6 ankyrin repeats OTBS_1195 64 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148285047 Common metG methionyl-tRNA synthetase OTBS_1947 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148284361 Pathogen rhp6 putative ompA-like autotransporter OTBS_0615 1 None None None 148284586 Common xseB exodeoxyribonuclease VII small subunit OTBS_1046 96 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 148284394 Common - peptidase U35, phage prohead HK97 OTBS_0681 45 COG3740 COG3740, Phage head maturation protease General function prediction only 148284117 Common - hypothetical protein OTBS_0219 15 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 148284883 Common nuoE NADH dehydrogenase I chain E OTBS_1631 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148284055 Common dam2 site-specific DNA adenine methylase OTBS_0126 68 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 148284265 Common cox11 cytochrome C oxidase assembly protein OTBS_0449 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 148284674 Common ppnK putative inorganic polyphosphate/ATP-NAD kinase OTBS_1220 92 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 148284697 Common ntrX NtrX-like response regualator/Sigma54 interactor/HTH, Fis type OTBS_1268 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148284796 Common trbC conjugative transfer protein OTBS_1478 9 None None None 148284248 Common dam4 site-specific DNA adenine methylase OTBS_0418 2 None None None 148284380 Common dnaB9 replicative DNA helicase OTBS_0651 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 148285004 Common topA DNA topoisomerase I OTBS_1844 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 148284638 Common traB conjugative pilus assembly protein OTBS_1152 24 None None None 148284527 Common tchB hypothetical protein OTBS_0939 2 None None None 148284940 Common traE conjugative transfer protein OTBS_1728 2 None None None 148284919 Common sdhC succinate dehydrogenase, cytochrome b556 subunit OTBS_1696 57 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 148284506 Pathogen ank1C6 ankyrin repeat protein with 2 ankyrin repeats OTBS_0902 1 None None None 148284837 Pathogen rhp7 hypothetical protein OTBS_1551 1 None None None 148284960 Common aatA aspartate aminotransferase A OTBS_1766 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148285146 Common - hypothetical protein OTBS_2124 82 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 148285037 Common - hypothetical protein OTBS_1916 93 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 148284817 Common tchB hypothetical protein OTBS_1509 2 None None None 148284752 Common ccmB heme exporter protein B OTBS_1393 2 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 148284121 Common yqiY amino acid ABC transporter permease protein OTBS_0224 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 148284042 Common ank1C1 ankyrin repeat protein with 4 ankyrin repeats OTBS_0098 42 None None None 148284561 Pathogen - hypothetical protein OTBS_1007 1 None None None 148284933 Common codA cytosine deaminase OTBS_1716 203 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 148284806 Common - hypothetical protein OTBS_1494 17 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 148285096 Common tchA hypothetical protein OTBS_2023 2 None None None 148284086 Pathogen - hypothetical protein OTBS_0170 1 None None None 148285018 Common traF conjugative pilus assembly protein OTBS_1875 13 None None None 148284516 Common - hypothetical protein OTBS_0921 79 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 148284066 Common psd phosphatidylserine decarboxylase OTBS_0145 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 148284209 Common rplV 50S ribosomal protein L22 OTBS_0371 219 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 148284874 Pathogen - hypthetical protein OTBS_1617 1 None None None 148284743 Common czcR CzcR-like response regulator OTBS_1364 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148284408 Common fabI enoyl-[acyl carrier protein] reductase OTBS_0706 227 COG0623 FabI, Enoyl- acyl-carrier-protein 148284200 Common rpsH 30S ribosomal protein S8 OTBS_0362 236 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 148284824 Common traD_Ti conjugative transfer protein OTBS_1523 3 None None None 148284071 Common sucD succinyl-CoA synthetase, alpha chain OTBS_0150 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 148284387 Pathogen - hypothetical protein OTBS_0674 1 None None None 148284744 Common - metallo-beta-lactamase family protein OTBS_1365 152 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only