Acidiphilium cryptum JF-5, complete genome NC_009484 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 148262075 Common - inner-membrane translocator Acry_3095 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148260392 Common - Thioredoxin domain protein Acry_1389 229 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148261120 Common - type III secretion exporter Acry_2129 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 148261165 Common - (2Fe-2S)-binding domain protein Acry_2175 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 148261090 Common - cytochrome c, class I Acry_2099 58 COG3474 COG3474, Cytochrome c2 Energy production and conversion 148259274 Common - AMP-dependent synthetase and ligase Acry_0254 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148259683 Common - (2Fe-2S)-binding domain protein Acry_0670 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 148260415 Common - Imidazoleglycerol-phosphate dehydratase Acry_1413 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 148259553 Common - FAD dependent oxidoreductase Acry_0537 118 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148260571 Common - acyl-CoA dehydrogenase domain protein Acry_1573 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148260707 Common - cobalt chelatase, pCobT subunit Acry_1711 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 148259072 Common - glycine dehydrogenase Acry_0051 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 148260616 Common - Cyclopropane-fatty-acyl-phospholipid synthase Acry_1618 129 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148260721 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Acry_1725 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 148260288 Common - transposase IS3/IS911 family protein Acry_1285 41 None None None 148260526 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Acry_1526 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261166 Common - molybdopterin dehydrogenase, FAD-binding Acry_2176 93 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 148259226 Common - glycosyl transferase, group 1 Acry_0206 123 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259267 Nonpathogen - hypothetical protein Acry_0247 2 None None None 148261922 Common - glycosyl transferase, family 2 Acry_2940 116 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148261230 Common - beta-Ig-H3/fasciclin Acry_2243 62 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 148261193 Common - inner-membrane translocator Acry_2203 115 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 148261125 Common - Flagellar basal body protein-like protein Acry_2134 23 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 148260421 Common - N-acetylglucosamine-6-phosphate deacetylase Acry_1419 124 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 148260691 Common rpsB 30S ribosomal protein S2 Acry_1694 223 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 148260635 Common - ABC transporter, transmembrane region, type 1 Acry_1637 247 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148260755 Common - inositol monophosphatase Acry_1760 188 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148259535 Common - flavin reductase domain protein, FMN-binding Acry_0519 73 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 148260431 Nonpathogen - Endonuclease/exonuclease/phosphatase Acry_1429 4 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 148260623 Common - succinyl-CoA synthetase, beta subunit Acry_1625 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 148261829 Nonpathogen - O-antigen polymerase Acry_2847 1 None None None 148259304 Nonpathogen - hypothetical protein Acry_0284 9 COG5421 COG5421, Transposase DNA replication, recombination, and repair 148260781 Common - processing peptidase Acry_1786 192 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 148259688 Common - protein of unknown function DUF1348 Acry_0675 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 148260981 Common - histone family protein DNA-binding protein Acry_1988 176 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148260314 Common - Nucleoside-diphosphate kinase Acry_1311 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 148259088 Common - Polypeptide-transport-associated domain protein, FtsQ-type Acry_0067 38 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 148261272 Common - HpcH/HpaI aldolase Acry_2285 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 148261206 Common - periplasmic binding protein/LacI transcriptional regulator Acry_2216 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259416 Common - chromosome segregation protein SMC Acry_0399 177 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148259809 Common - transposase, mutator type Acry_0798 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260375 Nonpathogen - hypothetical protein Acry_1372 2 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 148259981 Common - DNA polymerase III subunit delta' Acry_0971 93 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 148260462 Common - D-lactate dehydrogenase (cytochrome) Acry_1462 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 148260258 Common - hypothetical protein Acry_1255 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 148260732 Nonpathogen - hypothetical protein Acry_1736 1 None None None 148261188 Nonpathogen - hypothetical protein Acry_2198 1 None None None 148261578 Common - ABC-type sugar transport system periplasmic component-like protein Acry_2595 87 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148260670 Common - ABC transporter related Acry_1673 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 148259644 Common - major facilitator superfamily MFS_1 Acry_0630 65 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259800 Common - protein of unknown function DUF262 Acry_0789 47 COG3472 COG3472, Uncharacterized conserved protein Function unknown 148260846 Common - Monosaccharide-transporting ATPase Acry_1852 119 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260652 Common - ABC transporter related Acry_1655 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148260195 Common xerC site-specific tyrosine recombinase XerC Acry_1191 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148260173 Nonpathogen - hypothetical protein Acry_1169 1 None None None 148259935 Common - NADH dehydrogenase subunit D Acry_0924 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 148260565 Common - methyltransferase FkbM family Acry_1567 34 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 148261697 Nonpathogen - hypothetical protein Acry_2714 1 None None None 148260688 Common - TRAP dicarboxylate transporter, DctM subunit Acry_1691 124 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 148261119 Common - peptidase S16, lon domain protein Acry_2128 93 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 148260122 Common - bifunctional NADH:ubiquinone oxidoreductase subunit C/D Acry_1118 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 148260041 Common - Aldose 1-epimerase Acry_1033 96 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 148259276 Common - ABC-type Fe3+ transport system periplasmic component-like protein Acry_0256 6 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 148260531 Common - succinyl-diaminopimelate desuccinylase Acry_1531 203 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148261887 Common - Holliday junction DNA helicase RuvA Acry_2905 207 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 148261447 Common - AMP-dependent synthetase and ligase Acry_2463 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261062 Common - Cystathionine gamma-synthase Acry_2070 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 148260906 Common - Chromate transporter Acry_1913 16 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 148261005 Common - Pyruvate dehydrogenase (acetyl-transferring) Acry_2013 141 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 148260091 Nonpathogen - hypothetical protein Acry_1084 1 None None None 148260816 Common - Resolvase, N-terminal domain Acry_1822 94 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 148261787 Common - putative transcriptional regulator, AsnC family Acry_2804 148 COG1522 Lrp, Transcriptional regulators Transcription 148261860 Common - ammonium transporter Acry_2878 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 148260036 Nonpathogen - hypothetical protein Acry_1027 1 None None None 148259036 Common - twin-arginine translocation protein, TatA/E family subunit Acry_0015 91 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 148259514 Common - hypothetical protein Acry_0498 9 None None None 148260186 Common - preprotein translocase, YajC subunit Acry_1182 75 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 148260752 Common - NUDIX hydrolase Acry_1757 29 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 148260862 Common - 8-amino-7-oxononanoate synthase Acry_1868 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 148259669 Common - Rod shape-determining protein MreC Acry_0656 121 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 148259862 Common - transcriptional regulator, MarR family Acry_0851 44 COG1846 MarR, Transcriptional regulators Transcription 148259622 Common - NADH/Ubiquinone/plastoquinone (complex I) Acry_0608 102 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148261420 Common - Antibiotic biosynthesis monooxygenase Acry_2435 31 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 148260026 Common - protein tyrosine/serine phosphatase Acry_1017 15 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 148259160 Common - protein of unknown function DUF224, cysteine-rich region domain protein Acry_0140 144 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 148261932 Common - phosphate uptake regulator, PhoU Acry_2950 199 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 148261830 Nonpathogen - Methyltransferase type 11 Acry_2848 1 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 148259111 Common - acriflavin resistance protein Acry_0090 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148261868 Common - DNA gyrase, B subunit Acry_2886 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 148261324 Nonpathogen - integral membrane protein-like protein Acry_2338 1 COG5612 COG5612, Predicted integral membrane protein Function unknown 148259083 Common - cell cycle protein Acry_0062 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148261800 Nonpathogen - Septum formation initiator Acry_2818 5 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 148259917 Common - hydrolase, TatD family Acry_0906 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 148259255 Common - MscS Mechanosensitive ion channel Acry_0235 46 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148260641 Common - TonB family protein Acry_1643 7 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 148261391 Common - methyltransferase GidB Acry_2405 158 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 148261157 Common - Cytochrome-c oxidase Acry_2166 173 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 148261870 Common - transcriptional regulator, LysR family Acry_2888 190 COG0583 LysR, Transcriptional regulator Transcription 148259147 Common - Uroporphyrinogen III synthase HEM4 Acry_0127 2 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 148260678 Common - F0F1 ATP synthase subunit beta Acry_1681 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 148261505 Nonpathogen - phage baseplate assembly protein V Acry_2522 3 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 148261313 Common - HpcH/HpaI aldolase Acry_2327 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 148261755 Common - Fumarylacetoacetate (FAA) hydrolase family protein-like protein Acry_2772 35 COG3970 COG3970, Fumarylacetoacetate (FAA) hydrolase family protein General function prediction only 148260364 Nonpathogen - hypothetical protein Acry_1361 1 None None None 148260838 Common - DEAD/DEAH box helicase domain protein Acry_1844 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148259104 Nonpathogen - hypothetical protein Acry_0083 1 None None None 148261430 Common - outer membrane chaperone Skp (OmpH) Acry_2445 7 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 148260975 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Acry_1982 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 148261978 Nonpathogen - hypothetical protein Acry_2996 2 None None None 148261144 Common rpsP 30S ribosomal protein S16 Acry_2153 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 148260749 Nonpathogen - hypothetical protein Acry_1753 1 None None None 148259814 Common - hypothetical protein Acry_0803 28 None None None 148262033 Common - hypothetical protein Acry_3052 23 None None None 148259211 Common - 2-dehydropantoate 2-reductase Acry_0191 59 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 148260429 Common - NAD-glutamate dehydrogenase Acry_1427 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 148260169 Nonpathogen - hypothetical protein Acry_1165 1 None None None 148260661 Common - ribonuclease PH Acry_1664 181 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 148259308 Common - DegT/DnrJ/EryC1/StrS aminotransferase Acry_0289 197 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 148260106 Common - transcriptional regulator, LysR family Acry_1099 175 COG0583 LysR, Transcriptional regulator Transcription 148261344 Common - transposase, IS4 family protein Acry_2358 46 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261538 Common - undecaprenyl diphosphate synthase Acry_2555 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 148259387 Common - major facilitator superfamily MFS_1 Acry_0370 74 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 148259247 Common - Sua5/YciO/YrdC/YwlC family protein Acry_0227 221 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 148260022 Common hisS histidyl-tRNA synthetase Acry_1013 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148260831 Common - YdjC family protein Acry_1837 21 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 148261976 Common - oxidoreductase, molybdopterin binding Acry_2994 126 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 148261493 Nonpathogen - hypothetical protein Acry_2510 2 None None None 148260146 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Acry_1142 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 148259825 Common - Alpha/beta hydrolase fold-3 domain protein Acry_0814 49 COG0657 Aes, Esterase/lipase Lipid metabolism 148260062 Common - S-adenosylmethionine synthetase Acry_1054 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 148260446 Common - Na+/solute symporter Acry_1445 116 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148262025 Common - secreted protein-like protein Acry_3044 36 COG5501 COG5501, Predicted secreted protein Function unknown 148262008 Common - hypothetical protein Acry_3026 26 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148259865 Common - glycosyl transferase, group 1 Acry_0854 107 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261639 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Acry_2656 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 148261355 Common - periplasmic solute binding protein Acry_2369 47 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 148259566 Common - hypothetical protein Acry_0550 24 None None None 148259397 Common - fructose-bisphosphate aldolase Acry_0380 66 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 148261599 Common - dihydroxyacetone kinase, DhaK subunit Acry_2616 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 148261890 Common - glycosyl transferase, group 1 Acry_2908 24 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259292 Common - SmpA/OmlA domain protein Acry_0272 13 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 148261240 Common - protein of unknown function DUF81 Acry_2253 43 COG0730 COG0730, Predicted permeases General function prediction only 148260104 Nonpathogen - hypothetical protein Acry_1097 5 None None None 148260876 Common sdhB succinate dehydrogenase iron-sulfur subunit Acry_1882 202 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 148261530 Nonpathogen - hypothetical protein Acry_2547 1 None None None 148259996 Common - Substrate-binding region of ABC-type glycine betaine transport system Acry_0987 62 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 148261674 Common - maf protein Acry_2691 187 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 148259956 Common - FAD dependent oxidoreductase Acry_0945 81 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 148259096 Common - (2Fe-2S)-binding domain protein Acry_0075 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 148261152 Common - GntR domain protein Acry_2161 58 COG1802 GntR, Transcriptional regulators Transcription 148260777 Common - hypothetical protein Acry_1782 16 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 148259902 Nonpathogen - hypothetical protein Acry_0891 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 148260767 Common - ribosomal-protein-alanine acetyltransferase Acry_1772 11 COG0456 RimI, Acetyltransferases General function prediction only 148261879 Common - protein of unknown function DUF162 Acry_2897 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 148260815 Common - NIPSNAP family containing protein Acry_1821 14 None None None 148259218 Common - hypothetical protein Acry_0198 70 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 148259167 Common - electron transfer flavoprotein, alpha subunit Acry_0147 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 148260667 Common - KpsF/GutQ family protein Acry_1670 151 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 148259649 Nonpathogen - hypothetical protein Acry_0636 1 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 148260498 Common - Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Acry_1498 185 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 148261237 Common rplM 50S ribosomal protein L13 Acry_2250 219 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 148261809 Common - Cytochrome-c peroxidase Acry_2827 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 148260952 Common - glutamyl-tRNA synthetase Acry_1959 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148260957 Common - beta alanine--pyruvate transaminase Acry_1964 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 148261268 Common - magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase Acry_2281 97 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148259492 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Acry_0476 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 148259193 Common - OmpA/MotB domain protein Acry_0173 132 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148260536 Common - cation diffusion facilitator family transporter Acry_1536 186 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 148259718 Nonpathogen - hypothetical protein Acry_0705 1 None None None 148260407 Common - natural resistance-associated macrophage protein Acry_1405 83 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 148261933 Common - two component transcriptional regulator, winged helix family Acry_2951 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148259213 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Acry_0193 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148261944 Common - glycosyl transferase, group 1 Acry_2962 205 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261043 Common - hypothetical protein Acry_2051 23 None None None 148259631 Common - Deoxyribodipyrimidine photolyase-like protein Acry_0617 129 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 148259973 Common - thiamine biosynthesis protein ThiS Acry_0963 16 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 148261057 Common - Transketolase, central region Acry_2065 165 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 148260490 Common - Rhodanese domain protein Acry_1490 45 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148261220 Common - short-chain dehydrogenase/reductase SDR Acry_2232 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148260600 Common - Monosaccharide-transporting ATPase Acry_1602 150 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148261111 Common - riboflavin synthase subunit alpha Acry_2120 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 148259451 Common - ABC-2 type transporter Acry_0434 16 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 148260355 Common - phospholipid/glycerol acyltransferase Acry_1352 77 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 148260778 Common valS valyl-tRNA synthetase Acry_1783 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148259108 Common - dihydroxy-acid dehydratase Acry_0087 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148261525 Common - Ppx/GppA phosphatase Acry_2542 171 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 148261566 Nonpathogen - hypothetical protein Acry_2583 1 None None None 148260717 Common - orotidine 5'-phosphate decarboxylase Acry_1721 147 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 148261511 Common - hypothetical protein Acry_2528 49 None None None 148259144 Common - acyltransferase 3 Acry_0124 70 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 148260995 Common - Acid phosphatase Acry_2003 24 COG1409 Icc, Predicted phosphohydrolases General function prediction only 148259058 Common - ribonuclease R Acry_0037 192 COG0557 VacB, Exoribonuclease R Transcription 148259696 Common - extracellular solute-binding protein, family 3 Acry_0683 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148260791 Common - ABC-2 type transporter Acry_1796 142 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 148260598 Common - ABC transporter related Acry_1600 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259607 Common - glucose-1-phosphate cytidylyltransferase Acry_0591 156 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 148259580 Common - luciferase family protein Acry_0564 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 148259402 Common - hypothetical protein Acry_0385 5 None None None 148260211 Common - protein of unknown function DUF893, YccS/YhfK Acry_1207 40 COG1289 COG1289, Predicted membrane protein Function unknown 148261482 Common - amino acid permease-associated region Acry_2499 13 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 148261617 Common - Methyltransferase type 11 Acry_2634 84 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148259705 Nonpathogen - hypothetical protein Acry_0692 1 None None None 148260077 Common - hypothetical protein Acry_1069 12 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 148261437 Nonpathogen - hypothetical protein Acry_2452 1 None None None 148260017 Common - aspartate kinase Acry_1008 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148260259 Common - AMP-dependent synthetase and ligase Acry_1256 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148259737 Common - glycosyl transferase, family 2 Acry_0724 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148261550 Common - binding-protein-dependent transport systems inner membrane component Acry_2567 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148261471 Nonpathogen - hypothetical protein Acry_2487 1 None None None 148260455 Common - UvrD-like DNA helicase, C terminal Acry_1455 194 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 148259695 Common aat leucyl/phenylalanyl-tRNA--protein transferase Acry_0682 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 148261210 Nonpathogen - hypothetical protein Acry_2220 1 None None None 148259794 Common - hypothetical protein Acry_0782 90 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260704 Common - hypothetical protein Acry_1708 3 COG5373 COG5373, Predicted membrane protein Function unknown 148259746 Common - putative phage repressor Acry_0734 28 COG2932 COG2932, Predicted transcriptional regulator Transcription 148262007 Common - hypothetical protein Acry_3025 19 COG1416 COG1416, Uncharacterized conserved protein Function unknown 148260304 Common - poly(R)-hydroxyalkanoic acid synthase, class I Acry_1301 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 148259676 Common - hypothetical protein Acry_0663 16 None None None 148259846 Common - protein of unknown function DUF1491 Acry_0835 8 COG5447 COG5447, Uncharacterized conserved protein Function unknown 148261545 Nonpathogen - hypothetical protein Acry_2562 2 None None None 148261036 Common - oxidoreductase alpha (molybdopterin) subunit Acry_2044 176 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148261455 Common - hypothetical protein Acry_2471 49 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 148260613 Common - Deoxyribodipyrimidine photo-lyase Acry_1615 138 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 148260947 Common - ribosomal protein L10 Acry_1954 204 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 148259503 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Acry_0487 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259600 Common - MaoC domain protein dehydratase Acry_0584 94 COG2030 MaoC, Acyl dehydratase Lipid metabolism 148261508 Common - hypothetical protein Acry_2525 3 None None None 148261149 Common - ATP-dependent Clp protease proteolytic subunit Acry_2158 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148260483 Common - protein of unknown function DUF519 Acry_1483 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 148260698 Nonpathogen - protein of unknown function DUF81 Acry_1702 1 None None None 148259246 Common rbfA ribosome-binding factor A Acry_0226 158 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 148260477 Common - peptidase C26 Acry_1477 118 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 148261671 Common - Peptidoglycan-binding LysM Acry_2688 47 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 148260395 Common - efflux transporter, RND family, MFP subunit Acry_1393 134 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148259835 Common rbcL ribulose bisophosphate carboxylase Acry_0824 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 148261871 Common - Auxin Efflux Carrier Acry_2889 139 COG0679 COG0679, Predicted permeases General function prediction only 148260950 Common - OmpW family protein Acry_1957 71 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 148260439 Common - binding-protein-dependent transport systems inner membrane component Acry_1438 84 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 148260218 Common - glucose-1-phosphate thymidylyltransferase Acry_1215 225 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 148259934 Common - NADH (or F420H2) dehydrogenase, subunit C Acry_0923 171 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 148260194 Common - Biopolymer transport protein ExbD/TolR Acry_1190 119 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 148262013 Common - bifunctional enoyl-CoA hydratase/phosphate acetyltransferase Acry_3031 132 COG0280 Pta, Phosphotransacetylase Energy production and conversion 148262061 Common - phospholipid/glycerol acyltransferase Acry_3081 179 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 148261017 Common - glutathione synthetase Acry_2025 137 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 148261612 Common - pyridoxal phosphate biosynthetic protein PdxJ Acry_2629 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 148260963 Common - amine oxidase Acry_1970 22 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 148261046 Common - alanine racemase domain protein Acry_2054 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 148261402 Common - hypothetical protein Acry_2416 8 None None None 148261487 Common - chaperonin Cpn10 Acry_2504 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 148260427 Common - short-chain dehydrogenase/reductase SDR Acry_1425 121 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 148261440 Nonpathogen - hypothetical protein Acry_2455 1 None None None 148260203 Common - exodeoxyribonuclease VII, small subunit Acry_1199 126 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 148260733 Nonpathogen - hypothetical protein Acry_1737 1 None None None 148261307 Common - Xylose isomerase domain protein TIM barrel Acry_2321 26 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 148260310 Common - GTP-binding protein TypA Acry_1307 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 148261421 Common - hypothetical protein Acry_2436 15 None None None 148260865 Nonpathogen - hypothetical protein Acry_1871 1 None None None 148261180 Nonpathogen - hypothetical protein Acry_2190 1 None None None 148261243 Common - acetyl-CoA acetyltransferase Acry_2256 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 148260348 Common - LrgB family protein Acry_1345 24 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 148259386 Common - polynucleotide phosphorylase/polyadenylase Acry_0369 235 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 148259886 Common - glycoside hydrolase, family 24 Acry_0875 46 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 148260270 Common - transcriptional regulator, GntR family Acry_1267 134 COG1802 GntR, Transcriptional regulators Transcription 148259655 Common - prephenate dehydratase Acry_0642 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 148261414 Common - type III effector Hrp-dependent outer protein Acry_2429 56 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 148261673 Common - Ribonuclease G and E-like protein Acry_2690 8 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 148261175 Common - Glycine--tRNA ligase Acry_2185 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 148259733 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Acry_0720 121 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 148261993 Common - ectoine hydroxylase Acry_3011 37 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 148259864 Common - integral membrane sensor signal transduction histidine kinase Acry_0853 136 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148260913 Common - oligoendopeptidase, M3 family Acry_1920 64 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 148260603 Common - molybdenum cofactor biosynthesis protein A Acry_1605 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 148259903 Common - type II secretion system protein Acry_0892 123 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 148261410 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein Acry_2424 44 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 148261341 Common - 3-hydroxybutyrate dehydrogenase Acry_2355 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261135 Common - methyl-accepting chemotaxis sensory transducer Acry_2144 134 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148261580 Common - KDPG and KHG aldolase Acry_2597 119 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 148261085 Common - Rhs element Vgr protein Acry_2094 61 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 148261716 Nonpathogen - hypothetical protein Acry_2733 1 None None None 148259650 Common - Ni Fe-hydrogenase III large subunit-like protein Acry_0637 21 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 148260244 Nonpathogen - hypothetical protein Acry_1241 1 None None None 148261844 Common - OmpA/MotB domain protein Acry_2862 126 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148259363 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Acry_0344 165 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 148261777 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2794 203 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 148259128 Common - flagellin domain protein Acry_0108 52 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 148260385 Nonpathogen - hypothetical protein Acry_1382 3 None None None 148261820 Common - Serine-type D-Ala-D-Ala carboxypeptidase Acry_2838 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 148260883 Common - secretion protein HlyD family protein Acry_1890 130 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148261589 Common - Monosaccharide-transporting ATPase Acry_2606 175 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260298 Nonpathogen - hypothetical protein Acry_1295 1 None None None 148260185 Common - Superoxide dismutase Acry_1181 205 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 148261692 Common - putative CheW protein Acry_2709 133 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 148260324 Nonpathogen - hypothetical protein Acry_1321 1 None None None 148261638 Common - protein of unknown function YGGT Acry_2655 30 COG0762 COG0762, Predicted integral membrane protein Function unknown 148261781 Common - cytochrome c, class I Acry_2798 6 COG3258 COG3258, Cytochrome c Energy production and conversion 148260114 Common - proton-translocating NADH-quinone oxidoreductase, chain L Acry_1110 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 148259440 Common - protein of unknown function DUF152 Acry_0423 163 COG1496 COG1496, Uncharacterized conserved protein Function unknown 148260566 Common - short-chain dehydrogenase/reductase SDR Acry_1568 83 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259151 Common glgC glucose-1-phosphate adenylyltransferase Acry_0131 161 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 148260853 Common - Mannitol dehydrogenase rossman, N-terminal domain Acry_1859 86 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 148261985 Common - extracellular solute-binding protein, family 1 Acry_3003 73 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259256 Nonpathogen - hypothetical protein Acry_0236 1 COG3794 PetE, Plastocyanin Energy production and conversion 148260558 Common - oxygen-independent coproporphyrinogen III oxidase Acry_1560 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 148260970 Common - Glutathione S-transferase, N-terminal domain Acry_1977 90 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148261723 Common - undecaprenyl diphosphate synthase Acry_2740 241 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 148259595 Common - membrane-flanked domain Acry_0579 18 COG3428 COG3428, Predicted membrane protein Function unknown 148260289 Common - hypothetical protein Acry_1286 118 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260881 Common - multiple antibiotic resistance (MarC)-related protein Acry_1888 128 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 148260168 Common - transcriptional regulator, LysR family Acry_1164 131 COG0583 LysR, Transcriptional regulator Transcription 148261846 Common - cytochrome c biogenesis protein, transmembrane region Acry_2864 86 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148260837 Common - transcriptional regulator, BadM/Rrf2 family Acry_1843 147 COG1959 COG1959, Predicted transcriptional regulator Transcription 148261294 Nonpathogen - hypothetical protein Acry_2307 1 None None None 148260084 Common - Nitrile hydratase Acry_1077 21 None None None 148259711 Common - peptide chain release factor 3 Acry_0698 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 148260542 Common - L-aspartate oxidase Acry_1542 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 148260553 Nonpathogen - hypothetical protein Acry_1555 1 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 148260761 Common - aminotransferase, class V Acry_1766 207 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 148260925 Common rpsH 30S ribosomal protein S8 Acry_1932 240 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 148260533 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Acry_1533 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 148261744 Common - shikimate 5-dehydrogenase Acry_2761 220 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 148259086 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Acry_0065 187 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 148259877 Common - HAD-superfamily hydrolase, subfamily IIB Acry_0866 57 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 148260132 Common - cation diffusion facilitator family transporter Acry_1128 147 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 148260624 Common - AFG1-family ATPase Acry_1626 100 COG1485 COG1485, Predicted ATPase General function prediction only 148260888 Common - glycosyl transferase, family 2 Acry_1895 28 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148261104 Common - acyl-CoA dehydrogenase domain protein Acry_2113 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148261955 Nonpathogen - hypothetical protein Acry_2973 2 None None None 148260509 Common - Cyclopropane-fatty-acyl-phospholipid synthase Acry_1509 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148260743 Common - histidine ammonia-lyase Acry_1747 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 148261097 Common - protein of unknown function DUF6, transmembrane Acry_2106 21 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 148259615 Common - electron transport protein SCO1/SenC Acry_0600 91 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 148259202 Common - tartrate dehydrogenase Acry_0182 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148260568 Common - Pyrrolo-quinoline quinone Acry_1570 63 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 148261363 Common - 3-dehydroquinate dehydratase Acry_2377 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 148260934 Common rplV 50S ribosomal protein L22 Acry_1941 181 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 148261813 Common - hypothetical protein Acry_2831 10 None None None 148259282 Common - Glycine cleavage T-protein, C-terminal barrel Acry_0262 57 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 148261648 Common - phosphoribosylformylglycinamidine synthase II Acry_2665 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 148259449 Common - protein of unknown function DUF500 Acry_0432 37 COG2930 COG2930, Uncharacterized conserved protein Function unknown 148260302 Common - aminotransferase Acry_1299 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148259628 Common - dTDP-glucose 4,6-dehydratase Acry_0614 230 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 148261855 Common - replicative DNA helicase Acry_2873 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 148259341 Common - hypothetical protein Acry_0322 41 COG0657 Aes, Esterase/lipase Lipid metabolism 148259281 Common - Glutathione S-transferase, N-terminal domain Acry_0261 66 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148259662 Common - lipid A biosynthesis acyltransferase Acry_0649 105 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 148259690 Common - transcriptional regulator, LysR family Acry_0677 161 COG0583 LysR, Transcriptional regulator Transcription 148259542 Common - helicase c2 Acry_0526 122 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 148261559 Common - protein of unknown function UPF0126 Acry_2576 133 COG2860 COG2860, Predicted membrane protein Function unknown 148259485 Common - Na+/H+ antiporter NhaD and related arsenite permease-like protein Acry_0469 27 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 148262082 Common - protein-disulfide isomerase-like protein Acry_3102 39 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148260940 Common rpsJ 30S ribosomal protein S10 Acry_1947 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 148259894 Common - general secretion pathway protein G Acry_0883 63 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 148261362 Common - lysine 2,3-aminomutase YodO family protein Acry_2376 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 148259424 Nonpathogen - protein of unknown function DUF1150 Acry_0407 2 COG5568 COG5568, Uncharacterized small protein Function unknown 148260893 Common - flagellar motor protein MotA Acry_1900 106 COG1291 MotA, Flagellar motor component Cell motility and secretion 148261273 Common - pyrrolidone-carboxylate peptidase Acry_2286 57 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 148261837 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Acry_2855 123 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148259498 Common - Extracellular ligand-binding receptor Acry_0482 115 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148259750 Common nrdF ribonucleotide-diphosphate reductase subunit beta Acry_0738 159 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 148260232 Nonpathogen - hypothetical protein Acry_1229 5 None None None 148261560 Common - acyl-CoA dehydrogenase domain protein Acry_2577 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148259460 Common - protein of unknown function UPF0005 Acry_0443 111 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 148260266 Nonpathogen - hypothetical protein Acry_1263 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 148259024 Common - putative cold-shock DNA-binding domain protein Acry_0003 178 COG1278 CspC, Cold shock proteins Transcription 148260847 Common - periplasmic binding protein/LacI transcriptional regulator Acry_1853 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148261371 Common glpD glycerol-3-phosphate dehydrogenase Acry_2385 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148261767 Common - adenylosuccinate synthetase Acry_2784 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 148261033 Common - transcriptional regulators-like protein Acry_2041 39 COG1510 COG1510, Predicted transcriptional regulators Transcription 148259183 Common - recombination factor protein RarA Acry_0163 205 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 148260338 Common - Putative hemolysin-like protein Acry_1335 64 COG3176 COG3176, Putative hemolysin General function prediction only 148259545 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Acry_0529 188 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 148261285 Nonpathogen - hypothetical protein Acry_2298 1 None None None 148261815 Common - acetolactate synthase, large subunit, biosynthetic type Acry_2833 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 148261458 Common - Ferrochelatase Acry_2474 175 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 148261861 Nonpathogen - hypothetical protein Acry_2879 1 None None None 148261886 Common ruvB Holliday junction DNA helicase B Acry_2904 232 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 148261325 Common - Uncharacterized protein-like protein Acry_2339 43 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 148261729 Common - fumarate lyase Acry_2746 152 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 148261582 Common - short-chain dehydrogenase/reductase SDR Acry_2599 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259456 Common - histidinol-phosphate aminotransferase Acry_0439 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 148260341 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Acry_1338 44 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 148259550 Common - 2-isopropylmalate synthase Acry_0534 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 148260817 Common - ATPase AAA-2 domain protein Acry_1823 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148260121 Common - NADH-quinone oxidoreductase, E subunit Acry_1117 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148260905 Common - diguanylate phosphodiesterase Acry_1912 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 148261464 Common - CHRD domain containing protein Acry_2480 11 None None None 148260629 Common - putative transcriptional regulator, Crp/Fnr family Acry_1631 140 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148260751 Common - DEAD/DEAH box helicase domain protein Acry_1756 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 148260794 Common - Oxidoreductase FAD-binding domain protein Acry_1799 172 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 148261006 Common - sigma 54 modulation protein/ribosomal protein S30EA Acry_2014 56 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 148261857 Common - hypothetical protein Acry_2875 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 148261910 Common - ABC transporter related Acry_2928 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148261126 Common fliP flagellar biosynthesis protein FliP Acry_2135 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 148260640 Common - L-carnitine dehydratase/bile acid-inducible protein F Acry_1642 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 148259944 Common - proton-translocating NADH-quinone oxidoreductase, chain M Acry_0933 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 148261774 Common - extracellular solute-binding protein, family 3 Acry_2791 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148259668 Nonpathogen - hypothetical protein Acry_0655 1 None None None 148260362 Common - protein of unknown function DUF1330 Acry_1359 36 COG5470 COG5470, Uncharacterized conserved protein Function unknown 148261392 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Acry_2406 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 148260892 Common - GCN5-related N-acetyltransferase Acry_1899 124 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 148261831 Common - alpha/beta hydrolase fold Acry_2849 166 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148261423 Common - indolepyruvate ferredoxin oxidoreductase Acry_2438 94 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 148261706 Common - CitB domain protein Acry_2723 18 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 148261223 Common - Monosaccharide-transporting ATPase Acry_2236 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260491 Common - major facilitator superfamily MFS_1 Acry_1491 65 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261244 Common - 3-oxoacid CoA-transferase, A subunit Acry_2257 91 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 148259918 Common - beta-lactamase domain protein Acry_0907 74 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 148259863 Common - two component transcriptional regulator, winged helix family Acry_0852 205 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148261663 Common - acylphosphatase Acry_2680 120 COG1254 AcyP, Acylphosphatases Energy production and conversion 148260980 Common - hypothetical protein Acry_1987 16 None None None 148261730 Common - xanthine-guanine phosphoribosyltransferase Acry_2747 78 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 148260535 Common - integral membrane sensor signal transduction histidine kinase Acry_1535 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 148260099 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Acry_1092 25 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148261928 Common - cytochrome c1 Acry_2946 42 COG2857 CYT1, Cytochrome c1 Energy production and conversion 148260583 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Acry_1585 29 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148261983 Common - binding-protein-dependent transport systems inner membrane component Acry_3001 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148260577 Common - ATPase-like protein Acry_1579 28 COG0433 COG0433, Predicted ATPase General function prediction only 148261623 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Acry_2640 173 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 148260470 Common - GTP-binding signal recognition particle SRP54, G- domain Acry_1470 143 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 148260519 Common - glycosyl transferase, family 2 Acry_1519 25 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148259593 Common - two component transcriptional regulator, winged helix family Acry_0577 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148261570 Common - hypothetical protein Acry_2587 19 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 148259704 Nonpathogen - hypothetical protein Acry_0691 1 None None None 148259623 Common - protein of unknown function DUF190 Acry_0609 32 COG1993 COG1993, Uncharacterized conserved protein Function unknown 148260863 Common - biotin synthase Acry_1869 171 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 148260982 Nonpathogen - hypothetical protein Acry_1989 5 None None None 148260840 Common - 3-oxoacid CoA-transferase, A subunit Acry_1846 101 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 148259491 Common - Uncharacterized MobA-related protein-like protein Acry_0475 72 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 148259227 Common - ABC transporter related Acry_0207 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148262034 Common - protein of unknown function DUF302 Acry_3053 41 COG3439 COG3439, Uncharacterized conserved protein Function unknown 148260315 Nonpathogen - hypothetical protein Acry_1312 1 None None None 148261121 Common - type III secretion system inner membrane R protein Acry_2130 126 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 148261445 Nonpathogen - hypothetical protein Acry_2461 4 None None None 148261195 Common - Extracellular ligand-binding receptor Acry_2205 95 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148261923 Common - glycosyl transferase, group 1 Acry_2941 120 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259541 Nonpathogen - hypothetical protein Acry_0525 3 None None None 148260250 Nonpathogen - hypothetical protein Acry_1247 1 None None None 148259408 Common - voltage-gated potassium channel Acry_0391 103 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 148260789 Common - secretion protein HlyD family protein Acry_1794 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148260198 Common - inosine-5'-monophosphate dehydrogenase Acry_1194 238 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 148261754 Common - amidase Acry_2771 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148260233 Common - molybdenum cofactor synthesis domain protein Acry_1230 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 148260393 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Acry_1390 41 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 148259224 Common - response regulator receiver protein Acry_0204 20 COG4671 COG4671, Predicted glycosyl transferase General function prediction only 148260174 Common - phage integrase family protein Acry_1170 95 COG0582 XerC, Integrase DNA replication, recombination, and repair 148260680 Common - Malonyl-CoA decarboxylase Acry_1683 29 None None None 148259188 Common - Endoribonuclease L-PSP Acry_0168 99 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 148259087 Common - D-alanine--D-alanine ligase Acry_0066 205 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 148261517 Common - polyphosphate kinase Acry_2534 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 148260525 Common - malonyl CoA-acyl carrier protein transacylase Acry_1525 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 148259266 Common - translation elongation factor G Acry_0246 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 148260706 Common - OmpA/MotB domain protein Acry_1710 129 COG1360 MotB, Flagellar motor protein Cell motility and secretion 148261167 Common - major facilitator superfamily MFS_1 Acry_2177 133 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 148260825 Common - Radical SAM domain protein Acry_1831 106 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 148261917 Common - trehalose synthase Acry_2935 179 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148259477 Common - binding-protein-dependent transport systems inner membrane component Acry_0461 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148261739 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Acry_2756 84 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 148259554 Common - Glutamate--putrescine ligase Acry_0538 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 148259616 Common - hypothetical protein Acry_0601 24 None None None 148259856 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Acry_0845 188 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 148259231 Common - short-chain dehydrogenase/reductase SDR Acry_0211 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259195 Common - protein tyrosine/serine phosphatase Acry_0175 15 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 148260401 Common - hydrogenase 4 subunit F Acry_1399 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148259661 Common - amino acid permease-associated region Acry_0648 158 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 148259305 Common - transposase IS116/IS110/IS902 family protein Acry_0285 29 None None None 148259536 Common - methyl-accepting chemotaxis sensory transducer Acry_0520 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148261684 Common - short-chain dehydrogenase/reductase SDR Acry_2701 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261187 Nonpathogen - hypothetical protein Acry_2197 1 None None None 148259641 Common - short-chain dehydrogenase/reductase SDR Acry_0627 173 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259801 Common - transposase, mutator type Acry_0790 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261099 Common - transposase, mutator type Acry_2108 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261909 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2927 115 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 148259417 Common - Protein-disulfide isomerase-like protein Acry_0400 86 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148259273 Common - acyl-CoA dehydrogenase domain protein Acry_0253 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148261499 Nonpathogen - hypothetical protein Acry_2516 2 None None None 148259575 Common - ABC transporter domain protein Acry_0559 219 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 148261118 Common - Thioredoxin domain protein Acry_2127 218 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148260356 Common - RNA modification enzyme, MiaB family Acry_1353 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148260716 Common - integration host factor, beta subunit Acry_1720 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148259194 Common - OmpA/MotB domain protein Acry_0174 131 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148261260 Common - transcriptional regulator, BadM/Rrf2 family Acry_2273 61 COG1959 COG1959, Predicted transcriptional regulator Transcription 148261236 Common rpsI 30S ribosomal protein S9 Acry_2249 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 148260069 Common - oxidoreductase domain protein Acry_1061 112 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148261598 Common - C4-dicarboxylate transporter/malic acid transport protein Acry_2615 18 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 148260996 Common - hypothetical protein Acry_2004 32 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 148260161 Common - glyoxylate carboligase Acry_1157 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 148260294 Common - hypothetical protein Acry_1291 10 None None None 148260951 Common - aldo/keto reductase Acry_1958 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148259219 Common - peptidase M48, Ste24p Acry_0199 186 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 148260879 Common - phosphoenolpyruvate carboxykinase Acry_1886 99 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 148259338 Common - ABC transporter related Acry_0319 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148260406 Common cysS cysteinyl-tRNA synthetase Acry_1404 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148259107 Common - short-chain dehydrogenase/reductase SDR Acry_0086 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259921 Common - transcription elongation factor GreA Acry_0910 189 COG0782 GreA, Transcription elongation factor Transcription 148259589 Nonpathogen - hypothetical protein Acry_0573 1 None None None 148259670 Common - hypothetical protein Acry_0657 3 None None None 148261269 Common - hypothetical protein Acry_2282 32 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259497 Common - type II and III secretion system protein Acry_0481 140 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 148260499 Nonpathogen - hypothetical protein Acry_1499 1 None None None 148259166 Common - 3-hydroxybutyryl-CoA dehydrogenase Acry_0146 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 148259959 Common - arginyl-tRNA synthetase Acry_0949 240 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148259057 Common - putative ribonuclease BN Acry_0036 135 COG1295 Rbn, Predicted membrane protein Function unknown 148260669 Common - OstA family protein Acry_1672 12 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 148261044 Common - hypothetical protein Acry_2052 2 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 148260419 Common - imidazoleglycerol phosphate synthase, cyclase subunit Acry_1417 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 148259103 Common - RNA methyltransferase, TrmH family, group 3 Acry_0082 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 148259647 Common ileS isoleucyl-tRNA synthetase Acry_0633 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148261075 Common - Mammalian cell entry related domain protein Acry_2084 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 148260728 Common - regulatory protein, ArsR Acry_1732 24 COG0640 ArsR, Predicted transcriptional regulators Transcription 148260699 Common - hypothetical protein Acry_1703 2 None None None 148261943 Nonpathogen - hypothetical protein Acry_2961 1 None None None 148259125 Common - protein of unknown function DUF1217 Acry_0105 15 None None None 148260775 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Acry_1780 117 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 148261512 Nonpathogen - hypothetical protein Acry_2529 1 None None None 148260016 Common - ubiquinone biosynthesis O-methyltransferase Acry_1007 111 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 148260128 Common - molybdopterin dehydrogenase, FAD-binding Acry_1124 53 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 148259639 Common - 3-hydroxyisobutyrate dehydrogenase Acry_0625 156 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148259632 Common - short-chain dehydrogenase/reductase SDR Acry_0618 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259965 Common - hypothetical protein Acry_0955 28 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 148261567 Common - peptidase C39, bacteriocin processing Acry_2584 26 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 148261934 Common - hypothetical protein Acry_2952 6 None None None 148259710 Common - histone deacetylase superfamily Acry_0697 157 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 148260447 Common - hypothetical protein Acry_1446 9 None None None 148259139 Common - Squalene/phytoene synthase Acry_0119 72 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 148261965 Common - Monosaccharide-transporting ATPase Acry_2983 106 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260440 Common - ABC transporter related Acry_1439 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 148261477 Common - 5-formyltetrahydrofolate cyclo-ligase Acry_2493 180 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 148260103 Common - cytochrome c oxidase, subunit II Acry_1096 116 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 148260961 Common - Carbon-monoxide dehydrogenase (acceptor) Acry_1968 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148259630 Common - Amidase Acry_0616 213 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148259143 Nonpathogen - Transglycosylase-associated protein Acry_0123 1 COG2261 COG2261, Predicted membrane protein Function unknown 148260927 Common rplE 50S ribosomal protein L5 Acry_1934 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 148261808 Common - aromatic amino acid beta-eliminating lyase/threonine aldolase Acry_2826 73 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 148261822 Common - ATP-dependent Clp protease adaptor protein ClpS Acry_2840 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 148261786 Nonpathogen - siroheme synthase Acry_2803 10 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 148259531 Common - rare lipoprotein A Acry_0515 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 148260677 Common - ATP synthase F1, gamma subunit Acry_1680 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 148261506 Nonpathogen - hypothetical protein Acry_2523 2 None None None 148261314 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Acry_2328 223 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148261350 Common aspS aspartyl-tRNA synthetase Acry_2364 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148261977 Common - Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)-like protein Acry_2995 31 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 148261448 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Acry_2464 81 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 148259815 Common - hypothetical protein Acry_0804 73 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259824 Common - Glutathione S-transferase, N-terminal domain Acry_0813 62 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148261539 Common - phosphatidate cytidylyltransferase Acry_2556 211 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 148261591 Common - phenylacetate-CoA oxygenase, PaaG subunit Acry_2608 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 148259035 Common - GPR1/FUN34/yaaH family protein Acry_0014 49 COG1584 COG1584, Predicted membrane protein Function unknown 148260782 Common - threonine synthase Acry_1787 154 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 148259563 Common - Radical SAM domain protein Acry_0547 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 148259847 Common - formate/nitrite transporter Acry_0836 86 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 148259955 Common - ABC transporter related Acry_0944 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148259446 Common - Alcohol dehydrogenase GroES domain protein Acry_0429 159 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 148261975 Nonpathogen - hypothetical protein Acry_2993 10 None None None 148260764 Common - transcriptional regulator, DeoR family Acry_1769 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148261354 Common - ABC transporter related Acry_2368 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 148260079 Common - inner-membrane translocator Acry_1071 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148260987 Common - hypothetical protein Acry_1995 16 None None None 148261092 Common - ATP-dependent DNA helicase RecQ Acry_2101 227 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 148261893 Common - Uncharacterized enzyme of phosphonate metabolism-like protein Acry_2911 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 148261241 Nonpathogen - hypothetical protein Acry_2254 1 None None None 148261579 Common - Gluconolactonase Acry_2596 82 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 148259321 Common - ABC transporter related Acry_0302 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148259762 Common engA GTP-binding protein EngA Acry_0750 238 COG1160 COG1160, Predicted GTPases General function prediction only 148259309 Common - glycosyl transferase, group 1 Acry_0290 6 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259717 Common - transposase, IS4 family protein Acry_0704 29 None None None 148261655 Nonpathogen - hypothetical protein Acry_2672 1 None None None 148259062 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Acry_0041 163 COG0388 COG0388, Predicted amidohydrolase General function prediction only 148260556 Common - Phytanoyl-CoA dioxygenase Acry_1558 39 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 148260802 Common - CRISPR-associated protein Cas1 Acry_1808 48 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 148259293 Common - phosphatase-like protein Acry_0273 63 COG3211 PhoX, Predicted phosphatase General function prediction only 148260105 Common - Bile acid:sodium symporter Acry_1098 66 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 148260830 Common - Radical SAM domain protein Acry_1836 104 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148260692 Common tsf elongation factor Ts Acry_1695 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 148260920 Common - ribosomal protein L15 Acry_1927 132 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 148261207 Common - DNA replication protein-like protein Acry_2217 7 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148261253 Common - iron-sulfur cluster assembly accessory protein Acry_2266 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 148261494 Nonpathogen - hypothetical protein Acry_2511 1 None None None 148261531 Common - protein of unknown function DUF224, cysteine-rich region domain protein Acry_2548 150 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 148260311 Nonpathogen - hypothetical protein Acry_1308 1 None None None 148260154 Common - Uncharacterized protein-like protein Acry_1150 41 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 148261342 Nonpathogen - hypothetical protein Acry_2356 1 None None None 148261745 Common - short-chain dehydrogenase/reductase SDR Acry_2762 70 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261469 Common - Sel1 domain protein repeat-containing protein Acry_2485 81 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 148261016 Nonpathogen - hypothetical protein Acry_2024 1 None None None 148261058 Common - putative transcriptional regulator, AsnC family Acry_2066 168 COG1522 Lrp, Transcriptional regulators Transcription 148261682 Common - hypothetical protein Acry_2699 4 None None None 148260131 Common - protein of unknown function DUF156 Acry_1127 69 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 148259529 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Acry_0513 122 COG0546 Gph, Predicted phosphatases General function prediction only 148260418 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Acry_1416 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 148260340 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit Acry_1337 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 148260604 Common - protein of unknown function DUF1013 Acry_1606 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 148261422 Common - major facilitator superfamily MFS_1 Acry_2437 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148260426 Common - short-chain dehydrogenase/reductase SDR Acry_1424 181 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261050 Common - Uncharacterized protein-like protein Acry_2058 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 148262072 Common - Mn2+/Fe2+ transporter, NRAMP family Acry_3092 106 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 148259905 Common - peptidase A24A domain protein Acry_0894 36 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148261351 Common - ribonuclease D Acry_2365 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 148261063 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Acry_2071 41 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148261252 Common - Phosphoribosyl-AMP cyclohydrolase Acry_2265 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 148261839 Common - Cytochrome c biogenesis factor-like protein Acry_2857 13 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148260175 Common - hypothetical protein Acry_1171 21 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 148259904 Common - type II secretion system protein E Acry_0893 213 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 148260999 Common - ATPase associated with various cellular activities, AAA_3 Acry_2007 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 148261176 Common glyQ glycyl-tRNA synthetase subunit alpha Acry_2186 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 148259070 Common - glycine cleavage system T protein Acry_0049 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 148261284 Nonpathogen - hypothetical protein Acry_2297 1 None None None 148260039 Common - outer membrane autotransporter barrel domain Acry_1031 42 COG5571 COG5571, Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion Cell motility and secretion 148260914 Common - ribosomal protein L17 Acry_1921 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 148259182 Common - Uncharacterized protein-like protein Acry_0162 9 COG4322 COG4322, Uncharacterized protein conserved in bacteria Function unknown 148259658 Common - inositol monophosphatase Acry_0645 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148261086 Common - Polypeptide-transport-associated domain protein, ShlB-type Acry_2095 34 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 148261843 Nonpathogen - hypothetical protein Acry_2861 1 None None None 148259734 Common - hypothetical protein Acry_0721 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 148261413 Common - phage integrase family protein Acry_2428 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 148260803 Common - CRISPR-associated protein, Cse3 family Acry_1809 27 None None None 148260758 Common - hypothetical protein Acry_1763 16 None None None 148260202 Common - Polyprenyl synthetase Acry_1198 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148260083 Common - MscS Mechanosensitive ion channel Acry_1076 111 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148260964 Common - Monosaccharide-transporting ATPase Acry_1971 120 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 148259619 Common - NADH dehydrogenase (quinone) Acry_0605 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148261134 Common - acetylglutamate kinase Acry_2143 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 148261581 Common - 2-keto-3-deoxy-galactonokinase Acry_2598 38 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 148260276 Common - 6-phosphogluconolactonase Acry_1273 119 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 148260664 Common - putative oxidoreductase Acry_1667 194 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 148259049 Common - Carboxymuconolactone decarboxylase Acry_0028 25 COG2128 COG2128, Uncharacterized conserved protein Function unknown 148261266 Nonpathogen - hypothetical protein Acry_2279 1 None None None 148262026 Common - hypothetical protein Acry_3045 34 None None None 148259114 Common - transcriptional regulator, TetR family Acry_0093 94 COG1309 AcrR, Transcriptional regulator Transcription 148260597 Common - metallophosphoesterase Acry_1599 52 COG1409 Icc, Predicted phosphohydrolases General function prediction only 148261112 Common - riboflavin biosynthesis protein RibD Acry_2121 218 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 148259954 Nonpathogen - hypothetical protein Acry_0943 7 COG3431 COG3431, Predicted membrane protein Function unknown 148259203 Common - membrane protein-like protein Acry_0183 50 COG3174 COG3174, Predicted membrane protein Function unknown 148259769 Common - DNA ligase, NAD-dependent Acry_0757 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 148260210 Common - Uncharacterized protein UPF0114 Acry_1206 55 COG2862 COG2862, Predicted membrane protein Function unknown 148260337 Common - ferric uptake regulator, Fur family Acry_1334 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 148259425 Common - heat shock protein Hsp20 Acry_0408 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 148260265 Common - Alkane 1-monooxygenase Acry_1262 26 None None None 148260799 Nonpathogen - hypothetical protein Acry_1804 7 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 148259775 Common - glycosyl transferase, group 1 Acry_0763 173 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261618 Common - DNA-3-methyladenine glycosylase II Acry_2635 98 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 148261676 Common - Histidinol dehydrogenase Acry_2693 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 148259608 Common - CDP-glucose 4,6-dehydratase Acry_0592 191 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148259922 Common carB carbamoyl phosphate synthase large subunit Acry_0911 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 148260388 Nonpathogen - hypothetical protein Acry_1385 5 None None None 148261030 Common - single-strand binding protein Acry_2038 207 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 148259698 Common - ABC transporter related Acry_0685 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 148260454 Common - Inactivated superfamily I helicase-like protein Acry_1454 44 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 148260482 Common - oligoendopeptidase, pepF/M3 family Acry_1482 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 148261397 Common - DNA polymerase III subunit chi Acry_2411 28 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 148259403 Common - Fucolectin tachylectin-4 pentraxin-1 Acry_0386 11 None None None 148260078 Common - ABC-type sugar transport system periplasmic component-like protein Acry_1070 30 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148261438 Common - hypothetical protein Acry_2453 15 COG0716 FldA, Flavodoxins Energy production and conversion 148260659 Common - MaoC domain protein dehydratase Acry_1662 62 COG2030 MaoC, Acyl dehydratase Lipid metabolism 148260224 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Acry_1221 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 148261034 Common - protein of unknown function UPF0187 Acry_2042 55 COG3781 COG3781, Predicted membrane protein Function unknown 148260744 Common - N-formylglutamate amidohydrolase Acry_1748 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 148261544 Common - Uncharacterized membrane-associated protein-like protein Acry_2561 159 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 148260478 Common - RNA-binding S4 domain protein Acry_1478 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 148259659 Common - GCN5-related N-acetyltransferase Acry_0646 28 COG0456 RimI, Acetyltransferases General function prediction only 148260614 Common - amine oxidase Acry_1616 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 148260501 Common - isocitrate lyase Acry_1501 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 148259745 Common pyrB aspartate carbamoyltransferase catalytic subunit Acry_0733 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 148259030 Common - binding-protein-dependent transport systems inner membrane component Acry_0009 106 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 148259629 Common - glycosyl transferase, group 1 Acry_0615 48 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 148259504 Common - hypothetical protein Acry_0488 2 None None None 148260654 Common - binding-protein-dependent transport systems inner membrane component Acry_1657 164 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148259677 Common rpsD 30S ribosomal protein S4 Acry_0664 234 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 148260238 Common - hypothetical protein Acry_1235 99 None None None 148260465 Nonpathogen - hypothetical protein Acry_1465 5 None None None 148259793 Common - hypothetical protein Acry_0781 28 None None None 148260685 Common - methyltransferase FkbM family Acry_1688 16 None None None 148259834 Common - fructose-bisphosphate aldolase, class II, Calvin cycle subtype Acry_0823 171 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 148261812 Common - transcriptional regulator, LysR family Acry_2830 189 COG0583 LysR, Transcriptional regulator Transcription 148260915 Common - DNA-directed RNA polymerase subunit alpha Acry_1922 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 148259993 Common - extracellular solute-binding protein, family 1 Acry_0984 41 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 148261908 Common - protein of unknown function DUF1486 Acry_2926 17 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 148259023 Common - Carboxylesterase Acry_0002 93 COG0627 COG0627, Predicted esterase General function prediction only 148261194 Common - inner-membrane translocator Acry_2204 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148259042 Common - transcriptional regulator, XRE family Acry_0021 39 COG1396 HipB, Predicted transcriptional regulators Transcription 148259373 Common - ABC transporter related Acry_0356 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148261652 Common - pyruvate carboxylase Acry_2669 235 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 148259982 Common - methionyl-tRNA synthetase Acry_0972 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148261791 Common - hypothetical protein Acry_2808 6 None None None 148260353 Common - Methyltransferase type 12 Acry_1350 10 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 148259490 Common - Xanthine and CO dehydrogenase maturation factor XdhC/CoxF family-like protein Acry_0474 110 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 148260400 Common - Hydrogenase 4 membrane component (E)-like protein Acry_1398 38 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 148260217 Common - dTDP-glucose 4,6-dehydratase Acry_1214 230 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 148261558 Common - hypothetical protein Acry_2575 23 COG3347 COG3347, Uncharacterized conserved protein Function unknown 148259484 Common - sugar transporter Acry_0468 148 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148260739 Common - aldehyde dehydrogenase Acry_1743 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148262083 Common - O-succinylhomoserine sulfhydrylase Acry_3103 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 148260059 Common - inner-membrane translocator Acry_1051 119 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148260946 Common rplL 50S ribosomal protein L7/L12 Acry_1953 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 148261472 Common - Inorganic diphosphatase Acry_2488 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 148259150 Common - glycogen/starch/alpha-glucan phosphorylase Acry_0130 136 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 148260852 Common - mannonate dehydratase Acry_1858 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 148260011 Common - Oxidoreductase FAD-binding domain protein Acry_1002 165 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 148259874 Common - GCN5-related N-acetyltransferase Acry_0863 28 None None None 148259174 Common - hypothetical protein Acry_0154 12 None None None 148261689 Common - hypothetical protein Acry_2706 8 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 148260197 Common - Fmu (Sun) domain protein Acry_1193 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 148261306 Common - Inositol 2-dehydrogenase Acry_2320 106 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148261361 Common - Lysine--tRNA ligase Acry_2375 200 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 148259476 Common - binding-protein-dependent transport systems inner membrane component Acry_0460 166 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148261722 Common - protein of unknown function DUF347 Acry_2739 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 148261854 Common - hypothetical protein Acry_2872 23 None None None 148259280 Common - 2-nitropropane dioxygenase, NPD Acry_0260 87 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 148261561 Common - L-carnitine dehydratase/bile acid-inducible protein F Acry_2578 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 148260139 Common - extracellular solute-binding protein, family 3 Acry_1135 135 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148262064 Common - cell division ATP-binding protein FtsE Acry_3084 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 148259533 Common - sulfotransferase Acry_0517 21 None None None 148259881 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Acry_0870 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 148259189 Common - hypothetical protein Acry_0169 47 None None None 148261814 Common - acetolactate synthase, small subunit Acry_2832 189 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 148259787 Common - hypothetical protein Acry_0775 8 None None None 148261597 Nonpathogen - hypothetical protein Acry_2614 4 None None None 148261884 Common - MotA/TolQ/ExbB proton channel Acry_2902 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 148259358 Nonpathogen - protein of unknown function DUF1486 Acry_0339 2 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 148259722 Common - K+-transporting ATPase, B subunit Acry_0709 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 148259435 Common - transcriptional regulator, MarR family Acry_0418 16 COG1846 MarR, Transcriptional regulators Transcription 148261103 Common - aminoglycoside phosphotransferase Acry_2112 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 148259152 Common - glycogen/starch synthase, ADP-glucose type Acry_0132 150 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 148261717 Common - Glucose/sorbosone dehydrogenase-like protein Acry_2734 61 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 148260349 Nonpathogen - LrgA family protein Acry_1346 1 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 148261764 Common - ABC transporter related Acry_2781 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259157 Common - Phosphoglycerate mutase Acry_0137 3 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 148260113 Common - proton-translocating NADH-quinone oxidoreductase, chain M Acry_1109 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 148259546 Common - DNA-directed RNA polymerase, omega subunit Acry_0530 114 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 148261699 Common - protein of unknown function DUF1486 Acry_2716 15 COG5485 COG5485, Predicted ester cyclase General function prediction only 148259441 Common - protein of unknown function DUF185 Acry_0424 87 COG1565 COG1565, Uncharacterized conserved protein Function unknown 148260124 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Acry_1120 145 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 148261780 Common - Pyrrolo-quinoline quinone Acry_2797 74 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 148260978 Nonpathogen - hypothetical protein Acry_1985 1 None None None 148259610 Common - C-methyltransferase Acry_0594 43 None None None 148260882 Common - transcriptional regulator, MarR family Acry_1889 33 COG1846 MarR, Transcriptional regulators Transcription 148261994 Common - aspartate kinase Acry_3012 137 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148259257 Common - arginyl-tRNA-protein transferase Acry_0237 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 148261789 Common - protein of unknown function DUF1295 Acry_2806 35 COG3752 COG3752, Predicted membrane protein Function unknown 148261372 Common - transcriptional regulator, DeoR family Acry_2386 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148259596 Common - hypothetical protein Acry_0580 8 None None None 148260184 Common - Phytoene/squalene synthetase-like protein Acry_1180 39 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 148261986 Common - 3-oxoadipate enol-lactonase Acry_3004 122 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148261664 Common - ATP12 ATPase Acry_2681 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 148260549 Common - protein of unknown function DUF163 Acry_1551 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 148260361 Common - hypothetical protein Acry_1358 8 COG2267 PldB, Lysophospholipase Lipid metabolism 148259318 Common - ABC transporter related Acry_0299 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 148261023 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Acry_2031 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 148259756 Common - diaminopimelate decarboxylase Acry_0744 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 148261297 Common - hypothetical protein Acry_2310 88 None None None 148260836 Common - Truncated hemoglobin-like protein Acry_1842 45 COG2346 COG2346, Truncated hemoglobins General function prediction only 148260541 Common - quinolinate synthetase complex, A subunit Acry_1541 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 148261647 Common - phosphoribosylformylglycinamidine synthase I Acry_2664 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 148262006 Common - flavoprotein involved in K+ transport-like protein Acry_3024 71 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 148260880 Common - amidohydrolase Acry_1887 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 148259601 Common - glycosyl transferase, family 2 Acry_0585 86 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260160 Common - transcriptional regulator, LysR family Acry_1156 183 COG0583 LysR, Transcriptional regulator Transcription 148261662 Common - protein of unknown function UPF0118 Acry_2679 63 COG0628 PerM, Predicted permease General function prediction only 148259085 Common murC UDP-N-acetylmuramate--L-alanine ligase Acry_0064 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 148260926 Common rpsN 30S ribosomal protein S14 Acry_1933 205 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 148260376 Nonpathogen - hypothetical protein Acry_1373 1 COG1872 COG1872, Uncharacterized conserved protein Function unknown 148261821 Nonpathogen - phasin family protein Acry_2839 14 COG5490 COG5490, Uncharacterized conserved protein Function unknown 148261691 Common - CheA signal transduction histidine kinase Acry_2708 166 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 148260471 Common flhA flagellar biosynthesis protein A Acry_1471 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 148260578 Common - putative transcriptional regulator, Crp/Fnr family Acry_1580 21 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148259782 Common - transcriptional coactivator/pterin dehydratase Acry_0770 71 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 148259145 Common - HemY domain protein Acry_0125 4 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 148260988 Common - lipolytic enzyme, G-D-S-L family Acry_1996 21 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 148259077 Common - secreted (periplasmic) protein-like protein Acry_0056 8 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 148259966 Common - Sec-independent protein translocase, TatC subunit Acry_0956 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 148261592 Common - phenylacetate-CoA oxygenase, PaaH subunit Acry_2609 36 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 148261966 Common - ABC transporter related Acry_2984 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259326 Common - efflux transporter, RND family, MFP subunit Acry_0307 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148259910 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Acry_0899 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 148260443 Common - DoxX family protein Acry_1442 43 COG2259 COG2259, Predicted membrane protein Function unknown 148259142 Common - hypothetical protein Acry_0122 11 COG0392 COG0392, Predicted integral membrane protein Function unknown 148261518 Common - ATPase involved in DNA replication initiation-like protein Acry_2535 23 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148261807 Common - cyclase/dehydrase Acry_2825 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 148261436 Common - hypothetical protein Acry_2451 24 None None None 148262018 Common - hypothetical protein Acry_3036 6 None None None 148261311 Common - Xylose isomerase domain protein TIM barrel Acry_2325 65 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 148261491 Nonpathogen - hypothetical protein Acry_2508 2 None None None 148261336 Common - globin Acry_2350 18 COG2346 COG2346, Truncated hemoglobins General function prediction only 148260973 Common - sodium/hydrogen exchanger Acry_1980 188 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 148261155 Common - cytochrome c oxidase, subunit III Acry_2164 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 148260969 Common - NUDIX hydrolase Acry_1976 19 None None None 148259725 Nonpathogen - hypothetical protein Acry_0712 1 None None None 148262023 Common - cytochrome c, class I Acry_3042 27 COG2863 COG2863, Cytochrome c553 Energy production and conversion 148260516 Common - Propionyl-CoA carboxylase Acry_1516 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 148261318 Common - Uncharacterized protein-like protein Acry_2332 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 148261503 Nonpathogen - hypothetical protein Acry_2520 1 None None None 148260448 Common - Guanylate kinase Acry_1447 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 148260020 Common - Uncharacterized protein-like protein Acry_1011 84 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 148260150 Common - metal-dependent phosphohydrolase, HD sub domain Acry_1146 23 None None None 148261116 Common - protein of unknown function DUF343 Acry_2125 107 COG2835 COG2835, Uncharacterized conserved protein Function unknown 148261848 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like protein Acry_2866 11 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148259617 Nonpathogen - hypothetical protein Acry_0602 9 COG5031 COQ4, Uncharacterized protein involved in ubiquinone biosynthesis Coenzyme metabolism 148261353 Nonpathogen - ABC-3 protein Acry_2367 1 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148261637 Common - Fmu (Sun) domain protein Acry_2654 192 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 148261896 Common - phosphonate metabolism PhnJ Acry_2914 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 148260300 Common glpX fructose 1,6-bisphosphatase II Acry_1297 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 148261446 Common - 2-dehydropantoate 2-reductase Acry_2462 114 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 148259816 Common - transposase, mutator type Acry_0805 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261654 Common - multiple antibiotic resistance (MarC)-related protein Acry_2671 152 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 148260518 Nonpathogen - hypothetical protein Acry_1518 1 None None None 148260660 Common hrcA heat-inducible transcription repressor Acry_1663 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 148259134 Common - hypothetical protein Acry_0114 5 None None None 148259474 Common - transcriptional regulator, DeoR family Acry_0458 60 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148261304 Common - ABC-type sugar transport system periplasmic component-like protein Acry_2318 66 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259249 Common - methyltransferase FkbM family Acry_0229 14 None None None 148260358 Common - protein of unknown function UPF0054 Acry_1355 2 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 148259538 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Acry_0522 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148259568 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Acry_0552 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 148260134 Common - Co/Zn/Cd cation transporter-like protein Acry_1130 14 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 148260841 Common - beta-ketoadipyl CoA thiolase Acry_1847 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 148261100 Common - amino acid permease-associated region Acry_2109 179 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 148261568 Nonpathogen - hypothetical protein Acry_2585 1 None None None 148259106 Common - Nicotinamidase Acry_0085 104 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 148261853 Common - alanine racemase Acry_2871 191 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 148262029 Common - 5'-Nucleotidase domain protein Acry_3048 126 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 148259102 Common - pyrroloquinoline quinone biosynthesis protein PqqE Acry_0081 143 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 148260769 Common - hypothetical protein Acry_1774 56 COG0778 NfnB, Nitroreductase Energy production and conversion 148260096 Common - transcriptional regulator, TetR family Acry_1089 29 COG1309 AcrR, Transcriptional regulator Transcription 148259919 Common - peptidase M29, aminopeptidase II Acry_0908 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 148260001 Common - sarcosine oxidase, beta subunit family Acry_0992 97 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148259958 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Acry_0948 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 148260557 Common - SAF domain protein Acry_1559 36 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 148260997 Common - hypothetical protein Acry_2005 31 None None None 148261258 Common - FeS assembly ATPase SufC Acry_2271 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 148260014 Common - sulfatase Acry_1005 94 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 148261775 Common - cytochrome c, class I Acry_2792 29 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 148259588 Common - hypothetical protein Acry_0572 7 None None None 148259398 Common - thiamine-phosphate pyrophosphorylase Acry_0381 205 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 148260630 Nonpathogen - hypothetical protein Acry_1632 1 None None None 148260601 Nonpathogen - hypothetical protein Acry_1603 1 None None None 148259319 Common - efflux transporter, RND family, MFP subunit Acry_0300 26 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148261996 Nonpathogen - hypothetical protein Acry_3014 1 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 148261899 Common - phosphonate metabolism protein PhnM Acry_2917 52 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 148261951 Common - hypothetical protein Acry_2969 26 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 148259778 Common - peptidase S9, prolyl oligopeptidase active site domain protein Acry_0766 136 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 148259400 Common - glycosyl transferase, family 2 Acry_0383 49 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148261939 Common - integral membrane sensor signal transduction histidine kinase Acry_2957 148 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148261753 Nonpathogen - hypothetical protein Acry_2770 1 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 148260209 Nonpathogen - Capsular polysaccharide biosynthesis protein-like protein Acry_1205 7 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 148261527 Common - Uncharacterized protein-like protein Acry_2544 33 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 148261651 Common - hypothetical protein Acry_2668 28 None None None 148260102 Common - Cytochrome-c oxidase Acry_1095 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 148259694 Common - methyl-accepting chemotaxis sensory transducer Acry_0681 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148259925 Common - PII uridylyl-transferase Acry_0914 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 148259162 Nonpathogen - hypothetical protein Acry_0142 1 None None None 148260409 Common - amidase Acry_1407 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148260954 Common - dihydroorotate dehydrogenase 2 Acry_1961 190 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 148259448 Common - hypothetical protein Acry_0431 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 148260162 Common - Hydroxypyruvate isomerase Acry_1158 82 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 148260610 Common - exonuclease of the beta-lactamase fold involved in RNA processing-like protein Acry_1612 71 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 148261091 Common - hypothetical protein Acry_2100 10 None None None 148261222 Common - threonine dehydratase Acry_2234 194 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148259241 Common - toluene tolerance family protein Acry_0221 53 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 148259633 Common - AMP-dependent synthetase and ligase Acry_0619 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261946 Common - lipopolysaccharide biosynthesis protein Acry_2964 35 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 148260665 Common - NADH dehydrogenase (ubiquinone) Acry_1668 148 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148260381 Common - monooxygenase component MmoB/DmpM Acry_1378 9 None None None 148259045 Common - UDP-glucose 4-epimerase Acry_0024 231 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 148260071 Common - Monosaccharide-transporting ATPase Acry_1063 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148261040 Common holA DNA polymerase III subunit delta Acry_2048 50 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 148259272 Common - acyl-CoA dehydrogenase domain protein Acry_0252 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148259802 Nonpathogen - CopG domain protein DNA-binding domain protein Acry_0791 1 None None None 148259548 Common - holo-acyl-carrier-protein synthase Acry_0532 148 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 148261177 Nonpathogen - hypothetical protein Acry_2187 1 None None None 148259038 Common - hypothetical protein Acry_0017 109 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148259137 Common - amine oxidase Acry_0117 60 COG3349 COG3349, Uncharacterized conserved protein Function unknown 148261186 Common - threonyl-tRNA synthetase Acry_2196 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148261185 Common - glycosyl transferase, family 9 Acry_2195 56 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 148259306 Common - hypothetical protein Acry_0286 7 None None None 148259728 Common - transcriptional regulator, LysR family Acry_0715 158 COG0583 LysR, Transcriptional regulator Transcription 148260672 Common - peptidyl-tRNA hydrolase Acry_1675 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 148261191 Common - ABC transporter related Acry_2201 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148259302 Common - IstB domain protein ATP-binding protein Acry_0282 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148260864 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase Acry_1870 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 148260496 Common - glutaredoxin 3 Acry_1496 126 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 148260235 Common - Indole-3-glycerol-phosphate synthase Acry_1232 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 148260534 Common - Putative lipoprotein-like protein Acry_1534 33 COG3107 LppC, Putative lipoprotein General function prediction only 148259414 Common - F0F1 ATP synthase subunit A Acry_0397 201 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 148261168 Common - integral membrane sensor signal transduction histidine kinase Acry_2178 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148261078 Common - Uncharacterized protein-like protein Acry_2087 21 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 148260705 Common - hypothetical protein Acry_1709 31 COG5613 COG5613, Uncharacterized conserved protein Function unknown 148260423 Common - beta-lactamase domain protein Acry_1421 60 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148261462 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2478 171 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 148259555 Common - extracellular solute-binding protein, family 1 Acry_0539 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 148260286 Common - DoxX family protein Acry_1283 54 COG2259 COG2259, Predicted membrane protein Function unknown 148260251 Common - Polypeptide-transport-associated domain protein, ShlB-type Acry_1248 41 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 148260813 Nonpathogen - hypothetical protein Acry_1819 1 None None None 148261479 Common - signal recognition particle-docking protein FtsY Acry_2496 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 148259458 Common truB tRNA pseudouridine synthase B Acry_0441 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 148259196 Common - hypothetical protein Acry_0176 5 None None None 148260171 Nonpathogen - hypothetical protein Acry_1167 1 None None None 148259738 Common - Fe-S metabolism associated SufE Acry_0725 96 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 148259175 Common - phasin family protein Acry_0155 11 COG5490 COG5490, Uncharacterized conserved protein Function unknown 148259312 Common - Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Acry_0293 71 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 148260805 Common - CRISPR-associated protein, Cse4 family Acry_1811 42 None None None 148259685 Common - Enoyl-CoA hydratase/isomerase Acry_0672 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148259761 Nonpathogen - hypothetical protein Acry_0749 1 None None None 148260524 Common - polysaccharide export protein Acry_1524 38 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 148260502 Common - HhH-GPD family protein Acry_1502 206 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 148261963 Common - L-rhamnose 1-epimerase Acry_2981 39 COG3254 COG3254, Uncharacterized conserved protein Function unknown 148260811 Common - hypothetical protein Acry_1817 2 None None None 148261383 Common - acetyl-CoA acetyltransferase Acry_2397 91 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 148261218 Nonpathogen - hypothetical protein Acry_2230 1 None None None 148260188 Nonpathogen - TonB family protein Acry_1184 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 148261736 Common - acetoacetyl-CoA reductase Acry_2753 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259228 Nonpathogen - hypothetical protein Acry_0208 1 None None None 148259269 Common - signal peptidase I Acry_0249 199 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 148259937 Common - NADH-quinone oxidoreductase, F subunit Acry_0926 170 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148261107 Common - thiamine-monophosphate kinase Acry_2116 177 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 148261929 Common - 5'-methylthioadenosine phosphorylase Acry_2947 150 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 148261133 Common - GTP-binding protein, HSR1-related Acry_2142 193 COG0218 COG0218, Predicted GTPase General function prediction only 148260460 Common - MotA/TolQ/ExbB proton channel Acry_1460 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 148261866 Common - heat shock protein DnaJ domain protein Acry_2884 69 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 148260738 Common - protein of unknown function DUF779 Acry_1742 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 148259551 Common - alpha/beta hydrolase fold Acry_0535 161 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148260061 Common - tRNA (guanine-N(7)-)-methyltransferase Acry_1053 167 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 148261552 Common - ABC transporter related Acry_2569 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148259620 Common - NADH-ubiquinone oxidoreductase, chain 49kDa Acry_0606 166 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 148260990 Common - recombination protein RecR Acry_1998 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 148260712 Common - peptidase T2, asparaginase 2 Acry_1716 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 148259221 Nonpathogen - hypothetical protein Acry_0201 7 None None None 148262054 Common - virulence protein, SciE type Acry_3074 22 COG4455 ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion General function prediction only 148260343 Common - queuine tRNA-ribosyltransferase Acry_1340 229 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 148260848 Common - ABC transporter related Acry_1854 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148261704 Nonpathogen - protein of unknown function DUF1555 Acry_2721 1 None None None 148259052 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Acry_0031 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 148260267 Common - hypothetical protein Acry_1264 8 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 148260742 Common - imidazolonepropionase Acry_1746 100 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 148261322 Common - RNA polymerase sigma factor Acry_2336 21 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148260339 Common - protein of unknown function DUF1321 Acry_1336 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 148259570 Common - ABC transporter, transmembrane region, type 1 Acry_0554 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148261571 Common - sigma54 specific transcriptional regulator, Fis family Acry_2588 174 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 148260082 Nonpathogen - phosphate transporter Acry_1074 2 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 148261459 Common - uroporphyrinogen decarboxylase Acry_2475 174 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 148260469 Common - Cobyrinic acid a,c-diamide synthase Acry_1469 171 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148260394 Common - Rhodanese domain protein Acry_1392 40 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148262047 Common - transcriptional regulator, LysR family Acry_3066 186 COG0583 LysR, Transcriptional regulator Transcription 148259924 Common - DNA mismatch repair protein Acry_0913 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148260521 Nonpathogen - hypothetical protein Acry_1521 1 None None None 148260157 Common - protein of unknown function DUF182 Acry_1153 39 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 148259884 Common - Holliday junction resolvase YqgF Acry_0873 131 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 148260908 Common - phosphate ABC transporter, periplasmic phosphate-binding protein Acry_1915 132 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 148259703 Common - Substrate-binding region of ABC-type glycine betaine transport system Acry_0690 34 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 148261835 Common - cytochrome c-type biogenesis protein CcmE Acry_2853 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 148259431 Common - exodeoxyribonuclease III Xth Acry_0414 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 148260682 Common - squalene-hopene cyclase Acry_1685 42 COG1657 SqhC, Squalene cyclase Lipid metabolism 148259366 Nonpathogen - hypothetical protein Acry_0348 12 None None None 148262053 Common - uncharacterised conserved protein UCP028301 Acry_3073 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 148259729 Common - short-chain dehydrogenase/reductase SDR Acry_0716 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259434 Common - outer membrane lipoprotein carrier protein LolA Acry_0417 44 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 148259611 Nonpathogen - hypothetical protein Acry_0595 1 None None None 148260622 Common - succinyl-CoA synthetase, alpha subunit Acry_1624 208 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 148259879 Common - protein of unknown function DUF461 Acry_0868 52 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 148260181 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Acry_1177 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 148260326 Common - protein of unknown function DUF336 Acry_1323 47 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 148259489 Common - protein of unknown function DUF182 Acry_0473 111 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 148260835 Common - protein of unknown function DUF542, ScdA domain protein Acry_1841 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 148260309 Common - aldo/keto reductase Acry_1306 198 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 148262078 Common - haloacid dehalogenase, type II Acry_3098 62 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 148260741 Common - N-formimino-L-glutamate deiminase Acry_1745 62 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 148260387 Common - hypothetical protein Acry_1384 21 None None None 148261024 Common - putative TIM-barrel protein, nifR3 family Acry_2032 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 148260548 Common - gamma-glutamyl phosphate reductase Acry_1548 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 148260268 Nonpathogen - hypothetical protein Acry_1265 5 None None None 148260058 Common - inner-membrane translocator Acry_1050 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 148259153 Common - acriflavin resistance protein Acry_0133 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148260366 Common - glycosyl transferase, group 1 Acry_1363 121 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259442 Common - prolipoprotein diacylglyceryl transferase Acry_0425 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 148261296 Common - phage integrase family protein Acry_2309 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 148261725 Common - hypothetical protein Acry_2742 12 None None None 148260466 Common - FMN-binding negative transcriptional regulator Acry_1466 60 COG2808 PaiB, Transcriptional regulator Transcription 148260540 Common - hypothetical protein Acry_1540 29 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 148261150 Common - transcriptional regulator, LysR family Acry_2159 192 COG0583 LysR, Transcriptional regulator Transcription 148260763 Common - hydrolase of the alpha/beta superfamily-like protein Acry_1768 78 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 148261953 Common - eight transmembrane protein EpsH Acry_2971 19 None None None 148260156 Common - Transthyretin Acry_1152 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 148260007 Common - electron transfer flavoprotein, alpha subunit Acry_0998 151 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 148260555 Common - transcriptional regulator, GntR family Acry_1557 76 COG1802 GntR, Transcriptional regulators Transcription 148259598 Common recF recombination protein F Acry_0582 43 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 148261636 Common - transcriptional regulator, XRE family Acry_2653 20 COG1396 HipB, Predicted transcriptional regulators Transcription 148259375 Common - inner-membrane translocator Acry_0358 149 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 148261106 Common - hypothetical protein Acry_2115 231 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 148261328 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Acry_2342 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260886 Common - glycosyl transferase, group 1 Acry_1893 63 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261987 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_3005 111 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148259602 Nonpathogen - hypothetical protein Acry_0586 1 None None None 148261665 Common - AsmA family protein Acry_2682 47 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 148261690 Common - response regulator receiver protein Acry_2707 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148260895 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Acry_1902 189 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148261003 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Acry_2011 140 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 148259380 Common - OmpA/MotB domain protein Acry_0363 138 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148259788 Common - transposase, mutator type Acry_0776 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260916 Common - 30S ribosomal protein S11 Acry_1923 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 148260966 Common - Monosaccharide-transporting ATPase Acry_1973 102 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 148260118 Common - NADH dehydrogenase subunit H Acry_1114 185 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 148261765 Common - inner-membrane translocator Acry_2782 108 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259116 Common - transposase, IS4 family protein Acry_0095 46 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261885 Common - thioesterase superfamily protein Acry_2903 121 COG0824 FcbC, Predicted thioesterase General function prediction only 148259289 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Acry_0269 206 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 148260772 Common - Methyltransferase type 11 Acry_1777 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148260068 Common - TPR repeat-containing protein Acry_1060 70 COG0457 NrfG, FOG: TPR repeat General function prediction only 148260225 Common pgk phosphoglycerate kinase Acry_1222 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 148260216 Common - hypothetical protein Acry_1213 15 None None None 148261275 Common - acetate--CoA ligase Acry_2288 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 148262073 Common - ABC transporter related Acry_3093 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148259126 Nonpathogen - hypothetical protein Acry_0106 1 None None None 148259906 Common - hypothetical protein Acry_0895 62 COG3391 COG3391, Uncharacterized conserved protein Function unknown 148259741 Common anmK anhydro-N-acetylmuramic acid kinase Acry_0728 119 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 148261562 Common - hypothetical protein Acry_2579 33 COG3777 COG3777, Uncharacterized conserved protein Function unknown 148259496 Nonpathogen - hypothetical protein Acry_0480 1 COG4880 COG4880, Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats General function prediction only 148259342 Common - pyrroloquinoline quinone biosynthesis protein PqqC Acry_0323 34 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 148259547 Common - (p)ppGpp synthetase I, SpoT/RelA Acry_0531 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148259915 Common - peptidase M23B Acry_0904 87 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 148261817 Common - phosphoserine phosphatase SerB Acry_2835 148 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 148259022 Common dnaA chromosomal replication initiation protein Acry_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148261031 Common - cytochrome d ubiquinol oxidase, subunit II Acry_2039 155 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 148261790 Common - Methyltransferase type 11 Acry_2807 137 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148260855 Common - transcriptional regulator, GntR family Acry_1861 125 COG1802 GntR, Transcriptional regulators Transcription 148259098 Common - Carbon-monoxide dehydrogenase (acceptor) Acry_0077 75 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 148261553 Common - ABC transporter related Acry_2570 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148259204 Nonpathogen - CHAD domain containing protein Acry_0184 1 COG5607 COG5607, Uncharacterized conserved protein Function unknown 148262040 Common - hypothetical protein Acry_3059 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148260507 Common dcd deoxycytidine triphosphate deaminase Acry_1507 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 148261365 Common - acetyl-CoA carboxylase biotin carboxylase subunit Acry_2379 223 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 148260757 Common - RNA chaperone Hfq Acry_1762 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 148259129 Common - flagellar hook-associated protein FlgK Acry_0109 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 148259467 Common - two component transcriptional regulator, winged helix family Acry_0450 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148259785 Common - hypothetical protein Acry_0773 16 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260321 Common - sulfate adenylyltransferase, small subunit Acry_1318 140 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 148259487 Common - ATPase associated with various cellular activities, AAA_5 Acry_0471 96 COG0714 COG0714, MoxR-like ATPases General function prediction only 148259561 Common - putative aminotransferase Acry_0545 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 148261688 Common - methyl-accepting chemotaxis sensory transducer Acry_2705 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148261646 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Acry_2663 125 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 148259936 Common - NADH-quinone oxidoreductase, E subunit Acry_0925 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148261367 Common - diguanylate cyclase/phosphodiesterase Acry_2381 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148259133 Common - flagellar hook capping protein Acry_0113 84 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 148259946 Common - biotin--acetyl-CoA-carboxylase ligase Acry_0935 114 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 148260723 Common - short-chain dehydrogenase/reductase SDR Acry_1727 179 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 148261528 Common clpS ATP-dependent Clp protease adaptor protein ClpS Acry_2545 117 COG2127 COG2127, Uncharacterized conserved protein Function unknown 148259048 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Acry_0027 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 148259626 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Acry_0612 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 148261547 Common - carbohydrate kinase, FGGY Acry_2564 102 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148259113 Common - RND efflux system, outer membrane lipoprotein, NodT family Acry_0092 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148260397 Common - putative transcriptional regulator, XRE family Acry_1395 17 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 148261416 Common - 3-hydroxyisobutyrate dehydrogenase Acry_2431 136 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148260459 Common - aldo/keto reductase Acry_1459 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148261484 Common - Integral membrane protein-like protein Acry_2501 19 COG5488 COG5488, Integral membrane protein Function unknown 148259957 Common - exodeoxyribonuclease III Xth Acry_0946 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 148260797 Common - hypothetical protein Acry_1802 12 None None None 148261147 Common - NAD/NADP transhydrogenase alpha subunit-like protein Acry_2156 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 148259657 Common - cytochrome c, class I Acry_0644 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 148259796 Common - transposase IS66 Acry_0784 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261995 Common - major facilitator superfamily MFS_1 Acry_3013 97 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259739 Common - tyrosyl-tRNA synthetase Acry_0726 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148261698 Nonpathogen - hypothetical protein Acry_2715 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261619 Common - hypothetical protein Acry_2636 6 None None None 148261021 Common - isocitrate dehydrogenase Acry_2029 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148260584 Common - major facilitator superfamily MFS_1 Acry_1586 79 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 148260275 Common - ribose 5-phosphate isomerase Acry_1272 182 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 148260044 Common - hypothetical protein Acry_1036 2 None None None 148259502 Common - hypothetical protein Acry_0486 5 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 148261799 Nonpathogen - hypothetical protein Acry_2817 1 None None None 148261869 Nonpathogen - hypothetical protein Acry_2887 1 None None None 148259426 Common - peptide deformylase Acry_0409 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 148260101 Common - Heme/copper-type cytochrome/quinol oxidase subunit 3-like protein Acry_1094 91 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 148261239 Common - polyhydroxyalkonate synthesis repressor, PhaR Acry_2252 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 148259505 Nonpathogen - hypothetical protein Acry_0489 6 COG3652 COG3652, Predicted outer membrane protein Function unknown 148260373 Nonpathogen - hypothetical protein Acry_1370 1 None None None 148261489 Nonpathogen - hypothetical protein Acry_2506 1 None None None 148260433 Common - Esterase/lipase-like protein Acry_1431 41 COG0657 Aes, Esterase/lipase Lipid metabolism 148262005 Common - hypothetical protein Acry_3023 2 None None None 148259866 Nonpathogen - protein of unknown function DUF541 Acry_0855 3 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 148260824 Common - two component transcriptional regulator, winged helix family Acry_1830 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148262080 Nonpathogen - hypothetical protein Acry_3100 1 None None None 148259673 Common - nitric oxide dioxygenase Acry_0660 129 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 148260281 Common - GTP-binding protein LepA Acry_1278 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 148260637 Common - OsmC family protein Acry_1639 17 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148259388 Common - hypothetical protein Acry_0371 7 None None None 148260658 Common - transcriptional regulator, DeoR family Acry_1661 62 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 148259582 Common pyrE orotate phosphoribosyltransferase Acry_0566 111 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 148261002 Common - Polynucleotide adenylyltransferase region Acry_2010 207 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 148261918 Common - 1,4-alpha-glucan branching enzyme Acry_2936 143 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 148261262 Common - Nucleotidyl transferase Acry_2275 222 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 148259857 Nonpathogen - hypothetical protein Acry_0846 1 None None None 148259748 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Acry_0736 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 148261805 Common - dihydrolipoamide dehydrogenase Acry_2823 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148261404 Common - membrane protein-like protein Acry_2418 3 COG4713 COG4713, Predicted membrane protein Function unknown 148259039 Common - Acireductone dioxygenase, ARD Acry_0018 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 148261232 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Acry_2245 157 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148259050 Common - DNA topoisomerase IV subunit B Acry_0029 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 148259646 Common - lipoprotein signal peptidase Acry_0632 121 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148260453 Common - protein of unknown function UPF0079 Acry_1453 84 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 148261608 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Acry_2625 98 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148261212 Nonpathogen - hypothetical protein Acry_2223 1 None None None 148259837 Common - AAA ATPase, central domain protein Acry_0826 57 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 148259755 Common - hypothetical protein Acry_0743 25 None None None 148260643 Common - chaperone protein DnaK Acry_1646 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 148260201 Common - hypothetical protein Acry_1197 7 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260034 Common nusG transcription antitermination protein NusG Acry_1025 215 COG0250 NusG, Transcription antiterminator Transcription 148261435 Common - lactoylglutathione lyase Acry_2450 144 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 148261468 Common - permease for cytosine/purines, uracil, thiamine, allantoin Acry_2484 42 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 148259663 Common - tetraacyldisaccharide 4'-kinase Acry_0650 115 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 148260408 Common - acetylornithine deacetylase Acry_1406 181 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148260979 Common nadE NAD synthetase Acry_1986 202 COG0171 NadE, NAD synthase Coenzyme metabolism 148261208 Common - transcriptional regulator, PadR-like family Acry_2218 72 COG1695 COG1695, Predicted transcriptional regulators Transcription 148260615 Common - protein of unknown function DUF1365 Acry_1617 61 COG3496 COG3496, Uncharacterized conserved protein Function unknown 148259893 Common - Lytic transglycosylase, catalytic Acry_0882 21 None None None 148259299 Nonpathogen - phage integrase family protein Acry_0279 3 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148260253 Common - hypothetical protein Acry_1250 18 COG2353 COG2353, Uncharacterized conserved protein Function unknown 148261424 Common - putative ammonia monooxygenase Acry_2439 27 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 148261827 Common - Sterol desaturase-like protein Acry_2845 76 COG3000 ERG3, Sterol desaturase Lipid metabolism 148261974 Common - chaperone DnaJ domain protein Acry_2992 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 148262011 Common - Enoyl-(acyl-carrier-protein)-like protein Acry_3029 225 COG0623 FabI, Enoyl- acyl-carrier-protein 148259325 Common - ABC transporter related Acry_0306 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148260479 Common - putative methyltransferase Acry_1479 201 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 148260731 Nonpathogen - protein of unknown function DUF1555 Acry_1735 3 None None None 148260867 Nonpathogen - hypothetical protein Acry_1873 1 None None None 148259577 Common - secretion protein HlyD family protein Acry_0561 103 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148261473 Common - NAD-dependent epimerase/dehydratase Acry_2489 84 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148261980 Common - transcriptional regulator, LysR family Acry_2998 172 COG0583 LysR, Transcriptional regulator Transcription 148259365 Common - Rhodanese domain protein Acry_0346 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148261742 Common - polyhydroxyalkanoate depolymerase, intracellular Acry_2759 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 148259735 Nonpathogen - major facilitator superfamily MFS_1 Acry_0722 7 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259329 Nonpathogen - outer membrane efflux protein Acry_0310 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148260420 Common - phosphoribosyl-ATP pyrophosphohydrolase Acry_1418 165 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 148260048 Common - polysaccharide biosynthesis protein CapD Acry_1040 145 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148259346 Common - hydrogenase formation HypD protein Acry_0327 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 148259372 Common - protein of unknown function DUF344 Acry_0355 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 148259409 Common - phosphoribosylformylglycinamidine synthase, purS Acry_0392 92 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 148259844 Common - ABC transporter related Acry_0833 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 148262063 Common - protein of unknown function DUF214 Acry_3083 21 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 148260935 Common - ribosomal protein S19 Acry_1942 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 148260592 Common - Monosaccharide-transporting ATPase Acry_1594 107 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259994 Nonpathogen - hypothetical protein Acry_0985 2 None None None 148261305 Common - Xylose isomerase domain protein TIM barrel Acry_2319 14 COG4130 COG4130, Predicted sugar epimerase Carbohydrate transport and metabolism 148260591 Common - ABC transporter related Acry_1593 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148260687 Common - TRAP dicarboxylate transporter, DctP subunit Acry_1690 101 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 148260953 Common - HAD-superfamily subfamily IIA hydrolase like protein Acry_1960 67 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 148261569 Nonpathogen - hypothetical protein Acry_2586 1 None None None 148261209 Common - putative transcriptional regulators, CopG/Arc/MetJ family Acry_2219 10 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 148261788 Common - molybdenum cofactor biosynthesis protein B Acry_2805 163 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 148259720 Common lysK lysyl-tRNA synthetase Acry_0707 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 148259770 Common - transcriptional regulator, TraR/DksA family Acry_0758 146 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 148260998 Common - hypothetical protein Acry_2006 30 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 148261793 Common - regulatory protein, ArsR Acry_2811 62 COG0640 ArsR, Predicted transcriptional regulators Transcription 148259450 Common - Phosphoglycerate mutase Acry_0433 105 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 148260000 Common - choline dehydrogenase Acry_0991 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 148261263 Common - D-fructose-6-phosphate amidotransferase Acry_2276 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 148259587 Nonpathogen - hypothetical protein Acry_0571 1 None None None 148260489 Common - cysteine synthase A Acry_1489 218 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 148261238 Common - NAD-dependent epimerase/dehydratase Acry_2251 48 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148259495 Common - TPR repeat-containing protein Acry_0479 28 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 148260172 Nonpathogen - hypothetical protein Acry_1168 1 None None None 148259974 Common - glycine oxidase ThiO Acry_0964 151 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148259399 Common - Capsular polysaccharide biosynthesis protein-like protein Acry_0382 11 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 148261629 Common - molybdopterin oxidoreductase Fe4S4 region Acry_2646 182 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148259513 Common - Peptidoglycan glycosyltransferase Acry_0497 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148261973 Common - putative cold-shock DNA-binding domain protein Acry_2991 50 COG1278 CspC, Cold shock proteins Transcription 148261151 Common - hypothetical protein Acry_2160 18 None None None 148259401 Nonpathogen - hypothetical protein Acry_0384 1 None None None 148259051 Common - cytidylate kinase Acry_0030 210 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 148259105 Nonpathogen - hypothetical protein Acry_0084 3 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 148260149 Common - transcriptional regulator, AraC family Acry_1145 135 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 148261077 Common - protein phosphatase 2C domain protein Acry_2086 136 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 148259131 Nonpathogen - hypothetical protein Acry_0111 1 None None None 148261752 Common - putative agmatinase Acry_2769 154 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 148259506 Common - diguanylate cyclase/phosphodiesterase Acry_0490 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148259210 Common - thioesterase superfamily protein Acry_0190 63 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 148261650 Common - glutaredoxin-like protein Acry_2667 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 148259390 Common rpsU 30S ribosomal protein S21 Acry_0373 33 None None None 148260143 Common - Monosaccharide-transporting ATPase Acry_1139 99 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260057 Common - ABC transporter related Acry_1049 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148261497 Nonpathogen - hypothetical protein Acry_2514 2 None None None 148259168 Common - electron transfer flavoprotein beta-subunit Acry_0148 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 148259767 Common - DNA uptake lipoprotein-like protein Acry_0755 126 COG4105 ComL, DNA uptake lipoprotein General function prediction only 148261997 Common - Mammalian cell entry related domain protein Acry_3015 46 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 148259923 Common - carbamoyl phosphate synthase small subunit Acry_0912 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 148260363 Nonpathogen - hypothetical protein Acry_1360 1 None None None 148259212 Common - Uncharacterized protein-like protein Acry_0192 48 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 148259095 Common - GtrA family protein Acry_0074 5 COG2246 COG2246, Predicted membrane protein Function unknown 148259839 Common - cytosine deaminase Acry_0828 77 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 148260609 Common - ATP dependent DNA ligase Acry_1611 102 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 148259101 Common - coenzyme PQQ synthesis D Acry_0080 11 None None None 148259240 Common - VacJ family lipoprotein Acry_0220 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 148259528 Common - transcriptional regulator, TetR family Acry_0512 55 COG1309 AcrR, Transcriptional regulator Transcription 148261867 Common - N-acetylmuramoyl-L-alanine amidase, family 2 Acry_2885 108 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 148260729 Common - NADH:flavin oxidoreductase/NADH oxidase Acry_1733 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 148259909 Nonpathogen - hypothetical protein Acry_0898 1 None None None 148260208 Common - leucyl aminopeptidase Acry_1204 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 148260937 Common - Ribosomal protein L25/L23 Acry_1944 227 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 148260662 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Acry_1665 229 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 148260274 Common - glycoside hydrolase 15-related protein Acry_1271 70 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 148259327 Common - acriflavin resistance protein Acry_0308 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148262024 Common - cytochrome c, class I Acry_3043 15 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 148260449 Common - domain of unknown function DUF1732 Acry_1448 136 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 148261192 Common - ABC transporter related Acry_2202 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148260679 Common - ATP synthase F1, epsilon subunit Acry_1682 159 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 148259740 Common - hypothetical protein Acry_0727 7 COG5650 COG5650, Predicted integral membrane protein Function unknown 148260784 Common - N-acetyl-gamma-glutamyl-phosphate reductase Acry_1789 193 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 148261029 Common - TonB-dependent receptor Acry_2037 37 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148259686 Common - OmpA/MotB domain protein Acry_0673 132 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148261319 Common - NADH dehydrogenase (quinone) Acry_2333 204 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 148260049 Common - DegT/DnrJ/EryC1/StrS aminotransferase Acry_1041 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 148261352 Common - ABC-3 protein Acry_2366 3 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148261891 Common - glycosyl transferase, group 1 Acry_2909 24 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148262019 Common - transcriptional regulator, TetR family Acry_3038 65 COG1309 AcrR, Transcriptional regulator Transcription 148259578 Common - drug resistance transporter, EmrB/QacA subfamily Acry_0562 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261806 Common - lipoyl synthase Acry_2824 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 148259945 Common - proton-translocating NADH-quinone oxidoreductase, chain N Acry_0934 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 148259078 Common - Peptidoglycan glycosyltransferase Acry_0057 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148259712 Common - nuclease of the RecB family-like protein Acry_0699 7 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 148259148 Common - porphobilinogen deaminase Acry_0128 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 148260668 Common - protein of unknown function DUF1239 Acry_1671 10 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 148260804 Common - CRISPR-associated protein Cas5 family Acry_1810 35 None None None 148260515 Common - Enoyl-CoA hydratase/isomerase Acry_1515 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148259565 Nonpathogen - Uncharacterized protein putative amidase-like protein Acry_0549 4 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 148259141 Common - NAD-dependent epimerase/dehydratase Acry_0121 152 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148259609 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Acry_0593 162 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 148259719 Nonpathogen - hypothetical protein Acry_0706 1 None None None 148260463 Common - metallophosphoesterase Acry_1463 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 148259040 Common - 2,3-diketo-5-methylthio-1-phosphopentane phosphatase Acry_0019 31 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 148261680 Common - 3-hydroxyisobutyrate dehydrogenase Acry_2697 175 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148261056 Common - major facilitator superfamily MFS_1 Acry_2064 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259248 Common - glycosyl transferase, group 1 Acry_0228 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148260430 Common - ATP-dependent metalloprotease FtsH Acry_1428 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 148260849 Common - short chain dehydrogenase Acry_1855 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261492 Nonpathogen - hypothetical protein Acry_2509 1 None None None 148260510 Common - ribosomal protein L9 Acry_1510 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 148260023 Common - peptide chain release factor 1 Acry_1014 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 148261337 Common - hypothetical protein Acry_2351 14 None None None 148261303 Common - inner-membrane translocator Acry_2317 122 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148261287 Nonpathogen - hypothetical protein Acry_2300 1 None None None 148259817 Common - hypothetical protein Acry_0806 60 None None None 148260517 Common - glycosyl transferase WecB/TagA/CpsF Acry_1517 43 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 148261259 Common - cysteine desulfurase activator complex subunit SufB Acry_2272 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 148259790 Common - hypothetical protein Acry_0778 19 None None None 148259687 Common - Antibiotic biosynthesis monooxygenase Acry_0674 3 COG1359 COG1359, Uncharacterized conserved protein Function unknown 148261679 Common - L-carnitine dehydratase/bile acid-inducible protein F Acry_2696 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 148261956 Nonpathogen - Cupin 2, conserved barrel domain protein Acry_2974 2 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 148260730 Common - short-chain dehydrogenase/reductase SDR Acry_1734 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261115 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Acry_2124 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 148261653 Common - amine oxidase Acry_2670 19 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 148259481 Common - glucose-6-phosphate 1-dehydrogenase Acry_0465 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 148260737 Common - Pyrrolo-quinoline quinone Acry_1741 88 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 148260561 Common - Cytochrome c-like protein Acry_1563 17 COG3258 COG3258, Cytochrome c Energy production and conversion 148261878 Common - protein of unknown function DUF162 Acry_2896 65 COG1556 COG1556, Uncharacterized conserved protein Function unknown 148260529 Common - aminodeoxychorismate lyase Acry_1529 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 148259764 Common - Uncharacterized protein-like protein Acry_0752 3 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 148260090 Nonpathogen - hypothetical protein Acry_1083 1 COG4907 COG4907, Predicted membrane protein Function unknown 148261705 Common - tricarballylate dehydrogenase Acry_2722 68 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 148261425 Common - transcriptional regulator, LysR family Acry_2440 176 COG0583 LysR, Transcriptional regulator Transcription 148261312 Common - transcriptional regulator, RpiR family Acry_2326 82 COG1737 RpiR, Transcriptional regulators Transcription 148261915 Common - Amidase Acry_2933 213 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148261990 Common - L-2,4-diaminobutyric acid acetyltransferase Acry_3008 30 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 148259916 Common - phosphoglyceromutase Acry_0905 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 148261124 Common flgC flagellar basal body rod protein FlgC Acry_2133 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 148260081 Common - NADPH-dependent FMN reductase Acry_1073 71 COG0431 COG0431, Predicted flavoprotein General function prediction only 148260579 Common - nitrate reductase, alpha subunit Acry_1581 86 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 148259621 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Acry_0607 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 148260344 Common - 7-cyano-7-deazaguanine reductase Acry_1341 132 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 148259552 Nonpathogen - hypothetical protein Acry_0536 1 None None None 148261061 Common - Rieske (2Fe-2S) domain protein Acry_2069 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 148261323 Nonpathogen - hypothetical protein Acry_2337 1 None None None 148259618 Common - Formate hydrogenlyase subunit 4-like protein Acry_0603 69 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 148260060 Common - Extracellular ligand-binding receptor Acry_1052 135 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148260422 Common - iron-containing alcohol dehydrogenase Acry_1420 164 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 148260009 Common - NADH:flavin oxidoreductase/NADH oxidase Acry_1000 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 148261242 Common - alpha/beta hydrolase fold Acry_2255 52 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 148260930 Common - ribosomal protein S17 Acry_1937 227 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 148261898 Common - phosphonate C-P lyase system protein PhnL Acry_2916 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 148259271 Common era GTP-binding protein Era Acry_0251 224 COG1159 Era, GTPase General function prediction only 148261526 Common - hypothetical protein Acry_2543 7 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 148260468 Common - phage integrase family protein Acry_1468 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148261921 Common - hypothetical protein Acry_2939 7 None None None 148261049 Common - nicotinate phosphoribosyltransferase Acry_2057 104 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 148259205 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Acry_0185 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 148260628 Common - putative signal-transduction protein with CBS domains Acry_1630 134 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 148260295 Common - glycosyl transferase, family 2 Acry_1292 146 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148259987 Nonpathogen - Collagen triple helix repeat Acry_0977 1 None None None 148262048 Common - protein of unknown function DUF796 Acry_3068 24 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 148259362 Common - Polysulphide reductase, NrfD Acry_0343 25 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 148259854 Common - Alcohol dehydrogenase GroES domain protein Acry_0843 197 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 148260907 Common - Chromate transporter Acry_1914 19 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 148261170 Common - Orn/DAP/Arg decarboxylase 2 Acry_2180 182 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 148259693 Nonpathogen - hypothetical protein Acry_0680 1 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 148261931 Common - phosphate ABC transporter, ATPase subunit Acry_2949 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 148260097 Common - isocitrate lyase Acry_1090 120 COG2224 AceA, Isocitrate lyase Energy production and conversion 148261572 Nonpathogen - hypothetical protein Acry_2589 1 None None None 148259258 Nonpathogen - RDD domain containing protein Acry_0238 1 COG1714 COG1714, Predicted membrane protein/domain Function unknown 148260414 Common - major facilitator superfamily MFS_1 Acry_1412 146 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259313 Common - methyltransferase FkbM family Acry_0294 52 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 148259415 Nonpathogen - hypothetical protein Acry_0398 1 None None None 148260287 Common - transcriptional regulator, LysR family Acry_1284 120 COG0583 LysR, Transcriptional regulator Transcription 148261158 Common - cytochrome c oxidase, subunit II Acry_2167 148 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 148261169 Common - two component transcriptional regulator, winged helix family Acry_2179 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148259475 Common - extracellular solute-binding protein, family 1 Acry_0459 86 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259233 Common - heme exporter protein CcmA Acry_0213 247 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 148260072 Common - ABC transporter related Acry_1064 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259803 Common - hypothetical protein Acry_0792 45 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 148261184 Common - glycosyl transferase, group 1 Acry_2194 144 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148260572 Common - transcriptional regulator, TetR family Acry_1574 6 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 148260814 Nonpathogen - hypothetical protein Acry_1820 1 None None None 148259268 Common - Serine-type D-Ala-D-Ala carboxypeptidase Acry_0248 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 148259303 Common - Integrase, catalytic region Acry_0283 62 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260671 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Acry_1674 180 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 148261532 Common - FAD linked oxidase domain protein Acry_2549 155 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 148259938 Common - NADH dehydrogenase subunit G Acry_0927 194 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 148259060 Common - ribosomal protein L33 Acry_0039 126 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 148260252 Nonpathogen - hypothetical protein Acry_1249 1 None None None 148261384 Common - short-chain dehydrogenase/reductase SDR Acry_2398 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 148261211 Nonpathogen - hypothetical protein Acry_2222 1 None None None 148259300 Common - Uncharacterized protein-like protein Acry_0280 18 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 148261461 Common - methylated-DNA--protein-cysteine methyltransferase Acry_2477 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 148260187 Common - protein of unknown function DUF815 Acry_1183 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 148260636 Common - Cl- channel, voltage-gated family protein Acry_1638 163 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 148259590 Common - two component transcriptional regulator, winged helix family Acry_0574 202 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148261456 Common - conserved hypothetical protein 701 Acry_2472 96 COG1981 COG1981, Predicted membrane protein Function unknown 148259556 Common - binding-protein-dependent transport systems inner membrane component Acry_0540 183 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 148260497 Common - protein of unknown function DUF1178 Acry_1497 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 148261877 Common - Smr protein/MutS2 Acry_2895 30 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 148259510 Common - 3-hydroxybutyrate dehydrogenase Acry_0494 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261644 Common apaG ApaG Acry_2661 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 148261964 Common - Monosaccharide-transporting ATPase Acry_2982 95 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260523 Common - Non-specific protein-tyrosine kinase Acry_1523 112 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 148261004 Common - Ppx/GppA phosphatase Acry_2012 177 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 148261852 Common - protein of unknown function DUF140 Acry_2870 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 148261714 Common - binding-protein-dependent transport systems inner membrane component Acry_2731 190 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 148260753 Common - putative sulfite oxidase subunit YedY Acry_1758 125 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 148261737 Common - GCN5-related N-acetyltransferase Acry_2754 82 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 148259960 Common - Sporulation domain protein Acry_0950 10 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 148260382 Common - methane/phenol/toluene hydroxylase Acry_1379 16 None None None 148259229 Common - Phosphoglycerate mutase Acry_0209 152 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 148259465 Nonpathogen - hypothetical protein Acry_0448 1 None None None 148260792 Common - ABC-2 type transporter Acry_1797 177 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 148261364 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Acry_2378 180 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 148261687 Common - pyrroline-5-carboxylate reductase Acry_2704 193 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 148260928 Common - ribosomal protein L24 Acry_1935 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 148261219 Common - transcriptional regulator, LysR family Acry_2231 157 COG0583 LysR, Transcriptional regulator Transcription 148259115 Common - transcriptional regulator, PaaX family Acry_0094 20 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 148260301 Common - Homoserine dehydrogenase Acry_1298 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 148259780 Common - ABC transporter related Acry_0768 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148259259 Common - ribose-phosphate pyrophosphokinase Acry_0239 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 148259429 Common - translation initiation factor IF-3 Acry_0412 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 148259343 Common - NUDIX hydrolase Acry_0324 85 None None None 148260067 Common - Lytic transglycosylase, catalytic Acry_1059 165 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148261609 Common - Organic solvent tolerance protein Acry_2626 121 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 148259340 Common - hypothetical protein Acry_0321 81 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 148260119 Common - NADH-quinone oxidoreductase, chain G Acry_1115 184 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 148259466 Nonpathogen - hypothetical protein Acry_0449 1 None None None 148260711 Common - Enoyl-CoA hydratase/isomerase Acry_1715 164 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148260854 Common - short-chain dehydrogenase/reductase SDR Acry_1860 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148260111 Common - putative signal-transduction protein with CBS domains Acry_1107 161 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 148260199 Common - AMP-dependent synthetase and ligase Acry_1195 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261645 Common - Tetratricopeptide domain protein Acry_2662 94 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 148259184 Common - pseudouridine synthase, RluA family Acry_0164 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148259887 Nonpathogen - hypothetical protein Acry_0876 1 None None None 148260754 Common mazG nucleoside triphosphate pyrophosphohydrolase Acry_1759 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 148259559 Common - alanine dehydrogenase Acry_0543 163 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 148261563 Common - 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase Acry_2580 25 COG2030 MaoC, Acyl dehydratase Lipid metabolism 148259895 Common - hypothetical protein Acry_0884 3 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 148261032 Common - cytochrome bd ubiquinol oxidase, subunit I Acry_2040 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 148261816 Common - tRNA isopentenyltransferase Acry_2834 171 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 148260559 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_1561 77 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148261474 Common - Uncharacterized membrane-associated protein-like protein Acry_2490 127 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 148260877 Common - integral membrane sensor signal transduction histidine kinase Acry_1883 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148261882 Common - hypothetical protein Acry_2900 4 COG5373 COG5373, Predicted membrane protein Function unknown 148259786 Nonpathogen - hypothetical protein Acry_0774 1 None None None 148260718 Common - Phosphoribosylanthranilate isomerase Acry_1722 155 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 148261715 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Acry_2732 60 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 148261403 Common - glycosyl transferase, family 2 Acry_2417 101 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260320 Common - protease Do Acry_1317 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 148261117 Common - protein of unknown function DUF971 Acry_2126 54 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 148261087 Common - filamentous haemagglutinin family outer membrane protein Acry_2096 192 None None None 148259876 Common - Alpha,alpha-trehalose-phosphate synthase (UDP-forming) Acry_0865 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 148261370 Common - glycerol kinase Acry_2384 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 148259310 Common - glycosyl transferase, group 1 Acry_0291 83 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261320 Common - transcriptional regulator, LysR family Acry_2334 184 COG0583 LysR, Transcriptional regulator Transcription 148262081 Common - transcriptional regulator, TetR family Acry_3101 103 COG1309 AcrR, Transcriptional regulator Transcription 148259037 Common - twin-arginine translocation protein, TatA/E family subunit Acry_0016 21 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 148261783 Common - phosphoadenosine phosphosulfate reductase Acry_2800 159 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 148261481 Common - Diaminopimelate epimerase Acry_2498 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 148262052 Common - protein of unknown function DUF877 Acry_3072 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 148261762 Common - 3-hydroxyacyl-CoA dehydrogenase Acry_2779 138 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 148260438 Common - DNA polymerase III subunit beta Acry_1437 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 148259437 Common uvrC excinuclease ABC subunit C Acry_0420 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 148261724 Common - transcriptional regulator, LysR family Acry_2741 104 COG0583 LysR, Transcriptional regulator Transcription 148261415 Common - Hydroxypyruvate isomerase Acry_2430 75 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 148259511 Common - acetoacetate decarboxylase Acry_0495 18 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 148259488 Common - VWA containing CoxE family protein Acry_0472 45 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 148261847 Common - cytochrome c, class I Acry_2865 62 COG2863 COG2863, Cytochrome c553 Energy production and conversion 148259154 Common - acriflavin resistance protein Acry_0134 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148259307 Common - transposase, mutator type Acry_0287 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260547 Common - NUDIX hydrolase Acry_1547 165 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 148261105 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2114 169 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 148260325 Common - Extracellular ligand-binding receptor Acry_1322 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148259119 Common - Transposase and inactivated derivatives-like protein Acry_0098 58 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260006 Common - electron transfer flavoprotein beta-subunit Acry_0997 7 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 148259459 Common - ribosomal protein S15 Acry_0442 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 148260045 Nonpathogen - hypothetical protein Acry_1037 1 None None None 148260374 Nonpathogen - hypothetical protein Acry_1371 1 None None None 148260155 Common - protein of unknown function DUF989 Acry_1151 34 COG3748 COG3748, Predicted membrane protein Function unknown 148261299 Common - Myo-inositol catabolism IolB domain protein Acry_2313 52 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 148260710 Common - major facilitator superfamily MFS_1 Acry_1714 53 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148260976 Common - Nicotinic acid phosphoribosyltransferase-like protein Acry_1983 26 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 148262079 Common - Glutathione S-transferase, N-terminal domain Acry_3099 18 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148261798 Common - Uncharacterized protein-like protein Acry_2816 40 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 148259754 Common - ABC transporter related Acry_0742 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 148259486 Common - carbon monoxide dehydrogenase subunit G Acry_0470 38 COG3427 COG3427, Uncharacterized conserved protein Function unknown 148261845 Common - ATP-dependent helicase HrpB Acry_2863 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 148261076 Common - protein of unknown function DUF330 Acry_2085 2 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 148260621 Common - 2-oxoglutarate dehydrogenase, E1 subunit Acry_1623 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 148260948 Common rplA 50S ribosomal protein L1 Acry_1955 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 148261329 Common - Deoxyribodipyrimidine photo-lyase Acry_2343 130 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 148260834 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Acry_1840 152 COG1146 COG1146, Ferredoxin Energy production and conversion 148260330 Common - HNH endonuclease Acry_1327 103 COG1403 McrA, Restriction endonuclease Defense mechanisms 148259381 Common - Uncharacterized protein-like protein Acry_0364 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 148259581 Common - isocitrate dehydrogenase Acry_0565 67 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 148260889 Common - Sel1 domain protein repeat-containing protein Acry_1896 100 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 148261804 Common - GCN5-related N-acetyltransferase Acry_2822 62 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 148260651 Common - short-chain dehydrogenase/reductase SDR Acry_1654 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259443 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Acry_0426 217 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148261920 Common - 4-alpha-glucanotransferase Acry_2938 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 148261666 Common - hypothetical protein Acry_2683 5 None None None 148261018 Nonpathogen - hypothetical protein Acry_2026 1 None None None 148260226 Common - peptidase U62, modulator of DNA gyrase Acry_1223 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 148260910 Common - phosphate ABC transporter, inner membrane subunit PstA Acry_1917 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 148260936 Common rplB 50S ribosomal protein L2 Acry_1943 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 148260127 Common - oxidoreductase domain protein Acry_1123 144 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148260783 Common - preprotein translocase subunit SecB Acry_1788 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 148259892 Common - phosphoesterase Acry_0881 30 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 148260472 Common - two component, sigma54 specific, transcriptional regulator, Fis family Acry_1472 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148261010 Common - type II secretion system protein E Acry_2018 176 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 148259845 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Acry_0834 82 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 148261828 Common - 40-residue YVTN family beta-propeller repeat protein Acry_2846 76 COG3391 COG3391, Uncharacterized conserved protein Function unknown 148261019 Common - N-acetylmuramoyl-L-alanine amidase Acry_2027 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 148260642 Common - chaperone protein DnaJ Acry_1645 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 148262012 Common - Poly-beta-hydroxybutyrate polymerase domain protein Acry_3030 77 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 148260200 Common - protein of unknown function DUF1211 Acry_1196 31 COG3548 COG3548, Predicted integral membrane protein Function unknown 148260037 Nonpathogen - hypothetical protein Acry_1028 1 COG4907 COG4907, Predicted membrane protein Function unknown 148260428 Common - AMP-dependent synthetase and ligase Acry_1426 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261467 Common - 3-carboxy-cis,cis-muconate cycloisomerase Acry_2483 24 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 148259736 Common - undecaprenyl pyrophosphate phosphatase Acry_0723 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 148261672 Common - conserved hypothetical protein 730 Acry_2689 120 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 148260532 Common - hypothetical protein Acry_1532 4 None None None 148261200 Common - dihydroxy-acid dehydratase Acry_2210 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148261286 Nonpathogen - hypothetical protein Acry_2299 1 None None None 148259427 Common - methionyl-tRNA formyltransferase Acry_0410 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 148261274 Common - alpha/beta hydrolase fold Acry_2287 157 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148262041 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Acry_3060 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 148259075 Common - hypothetical protein Acry_0054 142 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 148260245 Common - oxidoreductase FAD/NAD(P)-binding domain protein Acry_1242 115 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 148261659 Common - major facilitator superfamily MFS_1 Acry_2676 104 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261642 Common - aldo/keto reductase Acry_2659 193 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148259347 Common - (NiFe) hydrogenase maturation protein HypF Acry_0328 109 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 148260602 Common - diguanylate cyclase Acry_1604 174 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148259527 Common - (2Fe-2S)-binding domain protein Acry_0511 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 148261330 Nonpathogen - hypothetical protein Acry_2344 1 None None None 148261551 Common - binding-protein-dependent transport systems inner membrane component Acry_2568 139 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148262059 Common - hypothetical protein Acry_3079 8 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 148261340 Common - phosphoheptose isomerase Acry_2354 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 148259324 Common - Citrate transporter Acry_0305 119 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 148260894 Common - OmpA/MotB domain protein Acry_1901 91 COG1360 MotB, Flagellar motor protein Cell motility and secretion 148259652 Common - Ribonuclease H Acry_0639 195 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 148259374 Common - ABC transporter related Acry_0357 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148260180 Nonpathogen - hypothetical protein Acry_1176 1 None None None 148259197 Common - Ethyl tert-butyl ether degradation EthD Acry_0177 19 None None None 148259316 Common - ABC-type Fe3+ transport system periplasmic component-like protein Acry_0297 53 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 148260452 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Acry_1452 190 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148260590 Common - 2-hydroxy-3-oxopropionate reductase Acry_1592 61 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148259795 Nonpathogen - hypothetical protein Acry_0783 2 None None None 148261945 Common - polysaccharide export protein Acry_2963 99 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 148259634 Common - 2-methylcitrate dehydratase Acry_0620 60 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 148260098 Nonpathogen - hypothetical protein Acry_1091 1 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 148260488 Common - Uncharacterized protein-like protein Acry_1488 35 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 148260481 Common - ABC-1 domain protein Acry_1481 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 148260823 Common - molybdopterin biosynthesis MoaE protein Acry_1829 98 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 148261836 Common - cytochrome c assembly protein Acry_2854 145 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148261546 Common - HAD-superfamily subfamily IIA hydrolase like protein Acry_2563 52 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 148260657 Common - carbohydrate kinase, FGGY Acry_1660 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148261515 Nonpathogen - hypothetical protein Acry_2532 1 None None None 148260342 Common - Queuosine biosynthesis protein Acry_1339 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 148261583 Common - ABC transporter related Acry_2600 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148260458 Common - major facilitator superfamily MFS_1 Acry_1458 133 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148260722 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Acry_1726 182 COG0756 Dut, dUTPase Nucleotide transport and metabolism 148261738 Common - OsmC family protein Acry_2755 39 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148261510 Common - Parallel beta-helix repeat Acry_2527 5 COG4257 Vgb, Streptogramin lyase Defense mechanisms 148260585 Common - Methylglyoxal synthase-like protein Acry_1587 14 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 148259230 Common - UDP-glucose 6-dehydrogenase Acry_0210 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 148261022 Common - drug resistance transporter, EmrB/QacA subfamily Acry_2030 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259643 Common - Alpha/beta hydrolase fold-3 domain protein Acry_0629 104 COG0657 Aes, Esterase/lipase Lipid metabolism 148261743 Common - dephospho-CoA kinase Acry_2760 193 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 148259627 Common - glucose-1-phosphate thymidylyltransferase Acry_0613 225 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 148259389 Common - DoxX family protein Acry_0372 20 COG2259 COG2259, Predicted membrane protein Function unknown 148260403 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Acry_1401 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 148260144 Common - ABC transporter related Acry_1140 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148261399 Common - HI0933 family protein Acry_2413 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 148259747 Nonpathogen - hypothetical protein Acry_0735 2 None None None 148260280 Common - bifunctional transaldolase/phosoglucose isomerase Acry_1277 209 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 148260303 Common - hypothetical protein Acry_1300 2 None None None 148260451 Common - Enoyl-CoA hydratase/isomerase Acry_1450 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148260599 Common - ABC-type sugar transport system periplasmic component-like protein Acry_1601 79 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148261148 Common - alanine dehydrogenase/PNT domain protein Acry_2157 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 148259080 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Acry_0059 201 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 148261988 Common - (2Fe-2S)-binding domain protein Acry_3006 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 148259675 Common - AMP-dependent synthetase and ligase Acry_0662 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148259867 Common - DEAD/DEAH box helicase domain protein Acry_0856 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148260313 Common - ABC transporter related Acry_1310 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148260133 Common - putative transcriptional regulator, MerR family Acry_1129 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 148261231 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Acry_2244 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 148261110 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Acry_2119 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 148261039 Common - hypothetical protein Acry_2047 9 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148259674 Common - hypothetical protein Acry_0661 33 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 148259836 Common - Ribulose-bisphosphate carboxylase Acry_0825 29 COG4451 RbcS, Ribulose bisphosphate carboxylase small subunit Energy production and conversion 148260508 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Acry_1508 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 148259190 Common - NADH:ubiquinone oxidoreductase 17.2 kD subunit Acry_0170 39 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 148259047 Common - CreA family protein Acry_0026 51 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 148260254 Nonpathogen - hypothetical protein Acry_1251 1 None None None 148261810 Common - NADPH-dependent FMN reductase Acry_2828 112 COG0431 COG0431, Predicted flavoprotein General function prediction only 148261378 Common - helix-turn-helix- domain containing protein, AraC type Acry_2392 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 148259344 Common - phenazine biosynthesis protein PhzF family Acry_0325 111 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 148261426 Common - thioredoxin reductase Acry_2441 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148259232 Common - aconitate hydratase Acry_0212 222 COG1048 AcnA, Aconitase A Energy production and conversion 148261418 Common - 6-phosphogluconate dehydrogenase, NAD-binding Acry_2433 171 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148259855 Common - FolC bifunctional protein Acry_0844 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 148261486 Common groEL chaperonin GroEL Acry_2503 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 148260860 Common - Extracellular ligand-binding receptor Acry_1866 157 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148262017 Common - hypothetical protein Acry_3035 2 None None None 148261613 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Acry_2630 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 148260273 Common - 3-isopropylmalate dehydrogenase Acry_1270 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148261141 Common rplS 50S ribosomal protein L19 Acry_2150 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 148260370 Common - Ada, metal-binding domain protein Acry_1367 89 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 148260992 Common - DNA polymerase III subunits gamma and tau Acry_2000 243 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 148261406 Nonpathogen - hypothetical protein Acry_2420 3 None None None 148261533 Common - FAD linked oxidase domain protein Acry_2550 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 148259708 Common - ETC complex I subunit conserved region Acry_0695 36 None None None 148260283 Common - hypothetical protein Acry_1280 60 None None None 148260617 Common - Na+/melibiose symporter and related transporter-like protein Acry_1619 93 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 148261215 Common - transposase, IS4 family protein Acry_2227 19 None None None 148259930 Common - ATP-dependent protease La Acry_0919 225 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 148259420 Common - DNA repair protein RadA Acry_0403 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 148262068 Common - helicase domain protein Acry_3088 62 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148260655 Common - extracellular solute-binding protein, family 1 Acry_1658 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259603 Common - major facilitator superfamily MFS_1 Acry_0587 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259672 Common - rod shape-determining protein RodA Acry_0659 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148260708 Common - cobalt chelatase, pCobS small subunit Acry_1712 68 COG0714 COG0714, MoxR-like ATPases General function prediction only 148261490 Common - phage uncharacterized protein Acry_2507 33 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 148260046 Common alaS alanyl-tRNA synthetase Acry_1038 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148259330 Common - two component transcriptional regulator, winged helix family Acry_0311 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148262043 Common - protein of unknown function UPF0157 Acry_3062 42 COG2320 GrpB, Uncharacterized conserved protein Function unknown 148259849 Common - formate dehydrogenase family accessory protein FdhD Acry_0838 121 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 148261640 Common - Lytic transglycosylase, catalytic Acry_2657 100 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148260080 Common - inner-membrane translocator Acry_1072 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260450 Common - DNA methylase N-4/N-6 domain protein Acry_1449 127 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 148260255 Common - membrane protein involved in aromatic hydrocarbon degradation Acry_1252 70 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 148261433 Common - UDP-N-acetylglucosamine acyltransferase Acry_2448 158 COG1043 LpxA, Acyl- acyl carrier protein 148261605 Common - Endoribonuclease L-PSP Acry_2622 111 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 148259170 Common - (Glutamate--ammonia-ligase) adenylyltransferase Acry_0150 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 148260457 Common - thioesterase superfamily protein Acry_1457 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 148259406 Common - hypothetical protein Acry_0389 12 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 148260869 Common - glutamate--cysteine ligase Acry_1875 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 148260779 Common - band 7 protein Acry_1784 203 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148261733 Nonpathogen - hypothetical protein Acry_2750 1 None None None 148259991 Common - ABC transporter related Acry_0981 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 148260740 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Acry_1744 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 148260073 Common - periplasmic lipoprotein-like protein Acry_1065 11 COG5618 COG5618, Predicted periplasmic lipoprotein General function prediction only 148260938 Common rplD 50S ribosomal protein L4 Acry_1945 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 148261408 Common - Site-specific DNA-methyltransferase (adenine-specific) Acry_2422 17 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 148262058 Common - Methyltransferase type 12 Acry_3078 25 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 148262066 Common - Membrane dipeptidase Acry_3086 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 148259135 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Acry_0115 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259198 Common - Pyruvate kinase Acry_0178 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 148259285 Common - asparagine synthase (glutamine-hydrolyzing) Acry_0265 143 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 148259572 Common - diguanylate phosphodiesterase Acry_0556 109 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 148261554 Common - carbohydrate kinase, FGGY Acry_2571 155 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148259155 Common - efflux transporter, RND family, MFP subunit Acry_0135 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148259237 Common - ribosomal L11 methyltransferase Acry_0217 172 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 148261264 Common - hypothetical protein Acry_2277 7 None None None 148260035 Common - preprotein translocase, SecE subunit Acry_1026 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 148261348 Common - major facilitator superfamily MFS_1 Acry_2362 65 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261369 Common - major intrinsic protein Acry_2383 91 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 148261740 Common - Organic radical activating enzymes-like protein Acry_2757 149 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 148259891 Nonpathogen - hypothetical protein Acry_0880 1 None None None 148260949 Common rplK 50S ribosomal protein L11 Acry_1956 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 148261696 Common - CheD, stimulates methylation of MCP proteins Acry_2713 83 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 148260714 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Acry_1718 59 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 148261053 Common - phosphoribosyltransferase Acry_2061 58 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 148259771 Nonpathogen - hypothetical protein Acry_0759 1 None None None 148261013 Common - Flp/Fap pilin component Acry_2021 12 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 148261072 Common - phospholipid/glycerol acyltransferase Acry_2080 36 COG3176 COG3176, Putative hemolysin General function prediction only 148261465 Common - dihydroneopterin aldolase Acry_2481 54 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 148259132 Nonpathogen - hypothetical protein Acry_0112 1 None None None 148261411 Common - Type IV secretory pathway VirD4 components-like protein Acry_2425 46 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 148260042 Common - recA protein Acry_1034 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 148260884 Common - drug resistance transporter, EmrB/QacA subfamily Acry_1891 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259348 Common - hydrogenase expression/formation protein HypE Acry_0329 122 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 148261201 Common - Carbon-monoxide dehydrogenase (acceptor) Acry_2211 105 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148260435 Common - O-methyltransferase-like protein Acry_1434 42 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 148260689 Common - short-chain dehydrogenase/reductase SDR Acry_1692 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259701 Nonpathogen - hypothetical protein Acry_0688 1 None None None 148260872 Common - methyltransferase-like protein Acry_1878 25 COG3897 COG3897, Predicted methyltransferase General function prediction only 148260220 Common - dTDP-4-dehydrorhamnose reductase Acry_1217 156 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 148261601 Common - dihydroxyacetone kinase, phosphotransfer subunit Acry_2618 202 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 148261927 Common - Cytochrome b/b6, N-terminal domain Acry_2945 143 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 148259927 Common tig trigger factor Acry_0916 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 148261584 Common - Monosaccharide-transporting ATPase Acry_2601 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259512 Common - Patatin Acry_0496 40 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 148262010 Nonpathogen - hypothetical protein Acry_3028 1 None None None 148261171 Common - Carboxymethylenebutenolidase Acry_2181 103 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 148260389 Common - hypothetical protein Acry_1386 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 148260594 Nonpathogen - hypothetical protein Acry_1596 1 None None None 148261393 Common - tRNA modification GTPase TrmE Acry_2407 218 COG0486 ThdF, Predicted GTPase General function prediction only 148259270 Common - Ribonuclease III Acry_0250 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 148260917 Common rpsM 30S ribosomal protein S13 Acry_1924 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 148261998 Common - ABC transporter related Acry_3016 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 148260248 Nonpathogen - hypothetical protein Acry_1245 1 None None None 148260607 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Acry_1609 228 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 148261331 Nonpathogen - hypothetical protein Acry_2345 2 None None None 148260215 Common - amidohydrolase Acry_1211 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 148261772 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Acry_2789 175 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 148262003 Common - methylmalonate-semialdehyde dehydrogenase Acry_3021 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148262004 Common - amidase, hydantoinase/carbamoylase family Acry_3022 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148259838 Common - Ribulose-phosphate 3-epimerase Acry_0827 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 148260089 Nonpathogen - hypothetical protein Acry_1082 1 None None None 148259798 Common - transposase IS3/IS911 family protein Acry_0786 18 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259526 Common - molybdopterin dehydrogenase, FAD-binding Acry_0510 72 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 148259354 Common - hydrogenase expression/formation protein Acry_0335 70 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 148259939 Common - NADH dehydrogenase (quinone) Acry_0928 189 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 148260901 Common - dihydrodipicolinate synthase Acry_1908 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148260986 Common - oxidoreductase domain protein Acry_1993 153 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148260673 Common - translation-associated GTPase Acry_1676 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 148259968 Common - beta-lactamase domain protein Acry_0958 202 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148259436 Common - Leucyl aminopeptidase Acry_0419 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 148261067 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Acry_2075 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148261660 Common - manganese transport regulator MntR Acry_2677 93 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 148261949 Common - AAA ATPase Acry_2967 73 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 148261726 Common - extracellular solute-binding protein, family 3 Acry_2743 152 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148259185 Common - surface antigen (D15) Acry_0165 144 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 148259350 Common - hydrogenase nickel insertion protein HypA Acry_0331 76 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 148260897 Common - Dolichyl-phosphate beta-D-mannosyltransferase Acry_1904 86 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148261298 Common - Transposase and inactivated derivatives-like protein Acry_2311 57 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259823 Common - hypothetical protein Acry_0812 21 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148260307 Common - cobalamin synthesis protein, P47K Acry_1304 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 148259377 Common - Extracellular ligand-binding receptor Acry_0360 138 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148261880 Common - Lytic transglycosylase, catalytic Acry_2898 45 None None None 148260627 Common - aminotransferase, class I and II Acry_1629 234 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148259591 Nonpathogen - hypothetical protein Acry_0575 1 None None None 148262070 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Acry_3090 152 COG1146 COG1146, Ferredoxin Energy production and conversion 148261989 Common - transcriptional regulator, MarR family Acry_3007 86 COG1846 MarR, Transcriptional regulators Transcription 148261841 Common - Cl- channel, voltage-gated family protein Acry_2859 101 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 148259473 Common - PfkB domain protein Acry_0457 169 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148259870 Common - diguanylate cyclase/phosphodiesterase Acry_0859 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148260279 Common - 6-phosphogluconate dehydrogenase-like protein Acry_1276 184 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 148259314 Common - TonB-dependent receptor Acry_0295 15 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148260178 Common - hypothetical protein Acry_1174 4 None None None 148260051 Nonpathogen - TRAP transporter solute receptor, TAXI family Acry_1043 5 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 148261905 Common rplT 50S ribosomal protein L20 Acry_2923 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 148260055 Common - major facilitator superfamily MFS_1 Acry_1047 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259907 Common - TonB-dependent receptor Acry_0896 80 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148261795 Common - arsenical pump membrane protein Acry_2813 94 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 148259123 Common - TPR repeat-containing protein Acry_0103 49 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 148259612 Common - NAD-dependent epimerase/dehydratase Acry_0596 35 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148260829 Common - Glycosyltransferase probably involved in cell wall biogenesis-like protein Acry_1835 29 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260833 Common - conserved hypothetical protein 701 Acry_1839 34 COG1981 COG1981, Predicted membrane protein Function unknown 148261643 Common - GTP cyclohydrolase I Acry_2660 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 148259666 Common - transcriptional regulator, LysR family Acry_0653 184 COG0583 LysR, Transcriptional regulator Transcription 148260921 Common - ribosomal protein L30 Acry_1928 92 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 148261302 Common - ABC transporter related Acry_2316 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148261667 Common - protein of unknown function DUF1022 Acry_2684 18 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 148259337 Common - inner-membrane translocator Acry_0318 95 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260620 Common - 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase Acry_1622 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148259715 Nonpathogen - hypothetical protein Acry_0702 1 None None None 148261712 Common - hypothetical protein Acry_2729 44 COG3665 COG3665, Uncharacterized conserved protein Function unknown 148259382 Common - tRNA(Ile)-lysidine synthetase Acry_0365 107 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 148259763 Common - Pyrrolo-quinoline quinone Acry_0751 86 COG1520 COG1520, FOG: WD40-like repeat Function unknown 148260334 Common - exodeoxyribonuclease VII, large subunit Acry_1331 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 148259322 Common - protein of unknown function DUF190 Acry_0303 14 COG1993 COG1993, Uncharacterized conserved protein Function unknown 148260646 Common - short-chain dehydrogenase/reductase SDR Acry_1649 75 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148259464 Common - HPr kinase Acry_0447 32 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 148260262 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Acry_1259 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148260260 Common - acetyl-CoA acetyltransferase Acry_1257 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 148259989 Common - metallophosphoesterase Acry_0979 68 COG1409 Icc, Predicted phosphohydrolases General function prediction only 148260136 Common - multicopper oxidase, type 2 Acry_1132 107 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 148260164 Common - Hydroxypyruvate reductase Acry_1160 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 148261089 Common - protein kinase Acry_2098 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 148259445 Common - maf protein Acry_0428 179 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 148259494 Common - phenylacetic acid degradation protein PaaD Acry_0478 71 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 148261685 Common rpmB 50S ribosomal protein L28 Acry_2702 139 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 148261916 Common - alpha amylase, catalytic region Acry_2934 97 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148260505 Common - hypothetical protein Acry_1505 10 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 148259297 Common - DNA binding domain, excisionase family Acry_0277 3 None None None 148261768 Common - tRNA synthetase, class II (G, H, P and S) Acry_2785 53 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 148260550 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Acry_1552 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148260328 Common - glutamyl-tRNA synthetase, class Ic Acry_1325 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148260008 Common - protein of unknown function DUF224, cysteine-rich region domain protein Acry_0999 91 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 148261883 Common - Biopolymer transport protein ExbD/TolR Acry_2901 141 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 148259783 Common - hypothetical protein Acry_0771 54 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148260243 Common - hypothetical protein Acry_1240 9 None None None 148261235 Common - transcriptional regulator, TrmB Acry_2248 81 COG1846 MarR, Transcriptional regulators Transcription 148260857 Common - ABC transporter related Acry_1863 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148260942 Common - 30S ribosomal protein S7 Acry_1949 240 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 148259522 Common - histone family protein DNA-binding protein Acry_0506 174 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148261293 Nonpathogen - hypothetical protein Acry_2306 1 None None None 148260094 Common - short-chain dehydrogenase/reductase SDR Acry_1087 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 148260379 Common groEL chaperonin GroEL Acry_1376 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 148259743 Common - DNA protecting protein DprA Acry_0730 207 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 148261375 Common - aldehyde dehydrogenase Acry_2389 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148259988 Common - transcriptional regulator, MarR family Acry_0978 47 COG1846 MarR, Transcriptional regulators Transcription 148260747 Common - N-formylglutamate amidohydrolase Acry_1751 53 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 148260546 Common - molybdopterin binding domain protein Acry_1546 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 148260725 Common - hypothetical protein Acry_1729 6 None None None 148259391 Common - peptide deformylase Acry_0374 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 148260117 Common - NADH-quinone oxidoreductase, chain I Acry_1113 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 148259768 Common - DNA repair protein RecN Acry_0756 197 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 148261708 Nonpathogen - hypothetical protein Acry_2725 1 None None None 148260586 Common - methyl-accepting chemotaxis sensory transducer Acry_1588 132 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148260790 Common - ABC transporter related Acry_1795 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148259774 Nonpathogen - hypothetical protein Acry_0762 1 None None None 148261291 Common - hypothetical protein Acry_2304 10 None None None 148259948 Common - beta-lactamase domain protein Acry_0937 151 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 148260367 Common - ABC transporter related Acry_1364 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148261396 Common - ATPase involved in chromosome partitioning-like protein Acry_2410 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148261278 Common - polysaccharide biosynthesis protein Acry_2291 51 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 148260807 Common - CRISPR-associated protein, Cse1 family Acry_1813 17 None None None 148261521 Common - phosphoribosylglycinamide formyltransferase Acry_2538 218 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 148261763 Common - ABC-type sugar transport system periplasmic component-like protein Acry_2780 86 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259833 Common - Phosphoribulokinase Acry_0822 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 148259091 Nonpathogen - hypothetical protein Acry_0070 1 None None None 148259804 Common - BsuBIPstI restriction endonuclease domain protein Acry_0793 16 None None None 148261094 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Acry_2103 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 148259079 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Acry_0058 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 148261719 Nonpathogen - hypothetical protein Acry_2736 1 None None None 148261938 Common - sugar transferase Acry_2956 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 148261961 Common - TadE family protein Acry_2979 15 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 148260703 Common - Inositol-phosphate phosphatase Acry_1707 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148260611 Common - DEAD/H associated domain protein Acry_1613 146 COG1201 Lhr, Lhr-like helicases General function prediction only 148262071 Common - transcriptional regulator, CarD family Acry_3091 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 148260236 Common - anthranilate phosphoribosyltransferase Acry_1233 239 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 148260163 Common - 2-hydroxy-3-oxopropionate reductase Acry_1159 176 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148261864 Common - NADH:flavin oxidoreductase/NADH oxidase Acry_2882 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 148260031 Common - UTP-glucose-1-phosphate uridylyltransferase Acry_1022 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 148259709 Common - protein of unknown function DUF192 Acry_0696 82 COG1430 COG1430, Uncharacterized conserved protein Function unknown 148259985 Common - hypothetical protein Acry_0975 13 COG0398 COG0398, Uncharacterized conserved protein Function unknown 148261129 Common - ribosomal protein L34 Acry_2138 189 None None None 148261901 Common - phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN Acry_2919 51 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 148260500 Common - protein of unknown function DUF955 Acry_1500 51 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 148261202 Common - glycosyl transferase, family 2 Acry_2212 23 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148259976 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Acry_0966 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148261160 Common - GcrA cell cycle regulator Acry_2169 32 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 148259413 Nonpathogen - H+-transporting two-sector ATPase, C subunit Acry_0396 1 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 148261803 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase Acry_2821 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148261216 Common - peptidase dimerisation domain protein Acry_2228 163 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148259753 Common - ABC-2 type transporter Acry_0741 112 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 148261734 Common - elongation factor G Acry_2751 248 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 148260822 Common - molybdopterin converting factor, subunit 1 Acry_1828 56 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 148259852 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Acry_0841 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148259557 Common - binding-protein-dependent transport systems inner membrane component Acry_0541 149 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 148260683 Common - peptide chain release factor 2 Acry_1686 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 148261454 Common - dihydroxy-acid dehydratase Acry_2470 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148261913 Common - inner-membrane translocator Acry_2931 140 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148259223 Nonpathogen - hypothetical protein Acry_0203 5 None None None 148259317 Common - ABC-type Fe3+ transport system permease component-like protein Acry_0298 24 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 148259518 Common - xylulokinase Acry_0502 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148259967 Common - seryl-tRNA synthetase Acry_0957 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 148261972 Common - methyl-accepting chemotaxis sensory transducer Acry_2990 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148259311 Common - glycosyl transferase, group 1 Acry_0292 20 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259579 Common - RND efflux system, outer membrane lipoprotein, NodT family Acry_0563 128 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148260029 Common - tryptophanyl-tRNA synthetase Acry_1020 221 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148260674 Common - primosome assembly protein PriA Acry_1677 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 148259480 Common - short-chain dehydrogenase/reductase SDR Acry_0464 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261620 Common - hypothetical protein Acry_2637 16 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 148260875 Common sdhA succinate dehydrogenase flavoprotein subunit Acry_1881 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 148260284 Nonpathogen - hypothetical protein Acry_1281 1 None None None 148262035 Common - phosphoesterase Acry_3054 32 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 148260902 Common - Lytic transglycosylase, catalytic Acry_1909 167 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148261009 Common - type II secretion system protein Acry_2017 76 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 148259207 Common - phosphoenolpyruvate-protein phosphotransferase Acry_0187 233 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 148260639 Common - short-chain dehydrogenase/reductase SDR Acry_1641 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261834 Common - heme exporter protein CcmC Acry_2852 125 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 148261875 Common - hypothetical protein Acry_2893 33 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 148260345 Common - domain of unknown function DUF1730 Acry_1342 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 148261255 Common - SUF system FeS assembly protein, NifU family Acry_2268 85 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 148260032 Common - MaoC domain protein dehydratase Acry_1023 8 COG2030 MaoC, Acyl dehydratase Lipid metabolism 148260528 Common - 3-oxoacyl-(acyl carrier protein) synthase II Acry_1528 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148260645 Nonpathogen - hypothetical protein Acry_1648 1 None None None 148260560 Common - DinB family protein Acry_1562 36 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 148261641 Nonpathogen - hypothetical protein Acry_2658 1 None None None 148260425 Common - Acetamidase/Formamidase Acry_1423 64 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 148261991 Common - diaminobutyrate--2-oxoglutarate aminotransferase Acry_3009 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 148259301 Common - GCN5-related N-acetyltransferase Acry_0281 45 COG3153 COG3153, Predicted acetyltransferase General function prediction only 148261316 Common - oxidoreductase domain protein Acry_2330 157 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148260842 Common - protocatechuate 3,4-dioxygenase, alpha subunit Acry_1848 36 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 148259665 Common - protein of unknown function DUF374 Acry_0652 9 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 148260574 Common - acetyl-CoA acetyltransferase Acry_1576 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 148262049 Common - ATPase AAA-2 domain protein Acry_3069 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148260985 Common minC septum formation inhibitor Acry_1992 95 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 148259433 Common - peptidase C26 Acry_0416 112 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 148261198 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Acry_2208 136 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 148261701 Common - RNA polymerase factor sigma-32 Acry_2718 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148261858 Common - RbsD or FucU transport Acry_2876 33 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 148260736 Nonpathogen - hypothetical protein Acry_1740 1 None None None 148259109 Nonpathogen - hypothetical protein Acry_0088 9 None None None 148260417 Common - GCN5-related N-acetyltransferase Acry_1415 30 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 148261702 Common - pseudouridine synthase, RluA family Acry_2719 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148260800 Common - glycosyl transferase, group 1 Acry_1805 101 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261748 Common - DNA polymerase III, epsilon subunit Acry_2765 182 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 148259702 Nonpathogen - hypothetical protein Acry_0689 1 None None None 148262028 Nonpathogen - hypothetical protein Acry_3047 1 None None None 148261888 Common ruvC Holliday junction resolvase Acry_2906 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 148261594 Common - phenylacetate-CoA oxygenase, PaaJ subunit Acry_2611 46 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 148259831 Common - response regulator receiver protein Acry_0820 37 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 148261782 Common - nitrite and sulphite reductase 4Fe-4S region Acry_2799 148 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 148260819 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Acry_1825 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 148260151 Common - Catalase Acry_1147 125 COG0753 KatE, Catalase Inorganic ion transport and metabolism 148260410 Nonpathogen - hypothetical protein Acry_1408 1 COG3462 COG3462, Predicted membrane protein Function unknown 148259829 Common - phosphomethylpyrimidine kinase Acry_0818 210 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 148261516 Nonpathogen - hypothetical protein Acry_2533 1 None None None 148260291 Common - methyl-accepting chemotaxis sensory transducer Acry_1288 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148259567 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Acry_0551 194 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 148259066 Common thyX FAD-dependent thymidylate synthase Acry_0045 39 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 148260399 Common - Formate hydrogenlyase subunit 4-like protein Acry_1397 95 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 148261066 Common - transcriptional regulator, LysR family Acry_2074 140 COG0583 LysR, Transcriptional regulator Transcription 148259100 Common - pyrroloquinoline quinone biosynthesis protein PqqC Acry_0079 43 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 148261227 Common - regulatory protein, IclR Acry_2240 121 COG1414 IclR, Transcriptional regulator Transcription 148259961 Common - Beta-N-acetylhexosaminidase Acry_0951 160 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 148261897 Common phnK phosphonates transport ATP-binding protein Acry_2915 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 148259604 Common - ABC transporter related Acry_0588 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148262051 Common - protein of unknown function DUF877 Acry_3071 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 148259140 Common - glycosyl transferase, family 2 Acry_0120 120 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260972 Common - hypothetical protein Acry_1979 7 None None None 148259368 Nonpathogen - hypothetical protein Acry_0351 1 None None None 148260360 Nonpathogen - hypothetical protein Acry_1357 1 None None None 148260514 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Acry_1514 231 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 148260693 Common - methyl-accepting chemotaxis sensory transducer Acry_1697 160 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148259032 Common - putative transcriptional regulator, ModE family Acry_0011 39 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 148261248 Common - protein of unknown function UPF0102 Acry_2261 14 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 148261338 Common - Resolvase, N-terminal domain Acry_2352 90 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 148259692 Common - protein of unknown function DUF983 Acry_0679 7 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 148260066 Common - phage SPO1 DNA polymerase-related protein Acry_1058 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148260319 Common - Pirin domain protein Acry_1316 143 COG1741 COG1741, Pirin-related protein General function prediction only 148261225 Common - ABC transporter related Acry_2238 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148261634 Common - phosphoserine aminotransferase Acry_2651 68 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 148259869 Nonpathogen - hypothetical protein Acry_0858 4 None None None 148260402 Common - NADH-ubiquinone oxidoreductase, chain 49kDa Acry_1400 192 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 148261109 Common - 6,7-dimethyl-8-ribityllumazine synthase Acry_2118 210 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 148259950 Common - prolyl-tRNA synthetase Acry_0939 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148260494 Common - Methyltransferase type 11 Acry_1494 78 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148259263 Common - Amidase Acry_0243 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148259951 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Acry_0940 227 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 148262050 Common - ImpA domain protein Acry_3070 26 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 148259163 Nonpathogen - hypothetical protein Acry_0143 1 None None None 148261678 Common - pyruvate carboxyltransferase Acry_2695 145 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 148259810 Nonpathogen - hypothetical protein Acry_0799 3 None None None 148260056 Common - ABC transporter related Acry_1048 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148260666 Common - 3'-5' exonuclease Acry_1669 98 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 148259818 Common - transposase IS116/IS110/IS902 family protein Acry_0807 73 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148261256 Common - cysteine desulfurase, SufS subfamily Acry_2269 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 148261501 Nonpathogen - hypothetical protein Acry_2518 1 None None None 148259392 Common - rpsU-divergently transcribed protein Acry_0375 25 COG5590 COG5590, Uncharacterized conserved protein Function unknown 148261792 Common - diguanylate phosphodiesterase Acry_2810 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 148259913 Common - protein of unknown function DUF610, YibQ Acry_0902 17 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 148261197 Nonpathogen - hypothetical protein Acry_2207 1 None None None 148260214 Nonpathogen - hypothetical protein Acry_1210 1 None None None 148261443 Common - Acetyltransferase including N-acetylase of ribosomal protein-like protein Acry_2459 14 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 148260785 Common - 2'-5' RNA ligase Acry_1790 129 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 148260207 Common - 3'(2'),5'-bisphosphate nucleotidase Acry_1203 178 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 148260991 Common - conserved hypothetical protein 103 Acry_1999 175 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 148261102 Common - Glutathione S-transferase, N-terminal domain Acry_2111 69 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148260473 Common - flagellar motor switch protein FliN Acry_1473 125 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 148260968 Common - ABC transporter related Acry_1975 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 148261153 Common - Carboxypeptidase Taq Acry_2162 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 148260003 Common - sarcosine oxidase, alpha subunit family Acry_0994 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 148261504 Nonpathogen - hypothetical protein Acry_2521 4 None None None 148259287 Common - putative transcriptional regulator, MerR family Acry_0267 76 COG0789 SoxR, Predicted transcriptional regulators Transcription 148262016 Common - permease for cytosine/purines, uracil, thiamine, allantoin Acry_3034 52 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 148261385 Common - NAD-dependent epimerase/dehydratase Acry_2399 69 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148261498 Nonpathogen - hypothetical protein Acry_2515 8 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 148260227 Common - cytochrome oxidase assembly Acry_1224 41 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 148259177 Common - hypothetical protein Acry_0157 19 None None None 148261851 Common - ABC transporter related Acry_2869 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 148259089 Common - cell division protein FtsA Acry_0068 180 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 148262042 Common - NAD(+) kinase Acry_3061 234 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 148261088 Nonpathogen - Uncharacterized protein-like protein Acry_2097 17 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 148261321 Nonpathogen - hypothetical protein Acry_2335 1 None None None 148261926 Common - coproporphyrinogen III oxidase Acry_2944 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 148261631 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Acry_2648 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148259714 Nonpathogen - hypothetical protein Acry_0701 1 None None None 148261948 Nonpathogen - hypothetical protein Acry_2966 3 None None None 148261359 Common - hypothetical protein Acry_2373 14 None None None 148259243 Common nusA transcription elongation factor NusA Acry_0223 220 COG0195 NusA, Transcription elongation factor Transcription 148261434 Common - protein of unknown function DUF1009 Acry_2449 44 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 148260774 Common - AMP-dependent synthetase and ligase Acry_1779 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 148259334 Common - CBS domain containing protein Acry_0315 133 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 148259136 Common - ROK family protein Acry_0116 164 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148259724 Nonpathogen - hypothetical protein Acry_0711 1 None None None 148261627 Common - DMSO reductase anchor subunit (DmsC) Acry_2644 16 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 148259635 Common - methylcitrate synthase Acry_0621 193 COG0372 GltA, Citrate synthase Energy production and conversion 148260442 Common - transcriptional regulator, LysR family Acry_1441 71 COG0583 LysR, Transcriptional regulator Transcription 148261626 Common - protein of unknown function DUF59 Acry_2643 16 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 148261332 Nonpathogen - hypothetical protein Acry_2346 3 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148259076 Common - S-adenosyl-methyltransferase MraW Acry_0055 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 148259214 Common - Radical SAM domain protein Acry_0194 65 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 148260632 Common - cytochrome d ubiquinol oxidase, subunit II Acry_1634 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 148261476 Common - protein of unknown function DUF710 Acry_2492 4 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 148261759 Common - aldo/keto reductase Acry_2776 179 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148261670 Common - phosphatidylserine decarboxylase Acry_2687 88 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 148260530 Common - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase Acry_1530 138 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 148261349 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2363 117 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 148261419 Common - putative aldolase Acry_2434 149 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148260480 Common - hypothetical protein Acry_1480 18 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 148261376 Common - aldehyde dehydrogenase Acry_2390 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148261695 Common - response regulator receiver protein Acry_2712 221 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 148261012 Common - SAF domain protein Acry_2020 58 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 148261020 Common - membrane protein-like protein Acry_2028 19 COG4852 COG4852, Predicted membrane protein Function unknown 148261179 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Acry_2189 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 148259999 Common - betaine aldehyde dehydrogenase Acry_0990 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148259843 Common - binding-protein-dependent transport systems inner membrane component Acry_0832 109 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 148260432 Common - phospholipase D/Transphosphatidylase Acry_1430 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 148261794 Common - arsenate reductase Acry_2812 115 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 148261000 Common - protein of unknown function DUF1285 Acry_2008 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 148260043 Nonpathogen - hypothetical protein Acry_1035 1 None None None 148261602 Common - hypothetical protein Acry_2619 16 None None None 148259176 Common - excinuclease ABC subunit B Acry_0156 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 148261741 Nonpathogen - hypothetical protein Acry_2758 2 None None None 148259439 Common - hypothetical protein Acry_0422 5 None None None 148259349 Common - hydrogenase accessory protein HypB Acry_0330 146 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 148260873 Common - succinate dehydrogenase, cytochrome b subunit Acry_1879 43 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 148261047 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Acry_2055 119 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148261540 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Acry_2557 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 148262060 Common - Uncharacterized membrane-associated protein-like protein Acry_3080 6 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 148261818 Common - CoA-binding domain protein Acry_2836 94 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 148260649 Common - homoserine kinase Acry_1652 67 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 148261585 Common - ABC-type sugar transport system periplasmic component-like protein Acry_2602 53 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148260593 Common - ABC-type sugar transport system periplasmic component-like protein Acry_1595 16 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148261292 Nonpathogen - hypothetical protein Acry_2305 1 None None None 148260608 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Acry_1610 196 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 148260795 Common - transcriptional regulator, BadM/Rrf2 family Acry_1800 162 COG1959 COG1959, Predicted transcriptional regulator Transcription 148261529 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Acry_2546 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148261610 Common - permease YjgP/YjgQ family protein Acry_2627 67 COG0795 COG0795, Predicted permeases General function prediction only 148261172 Common - hypothetical protein Acry_2182 7 None None None 148260713 Common - aspartate-semialdehyde dehydrogenase Acry_1717 235 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 148262002 Common - protein of unknown function DUF833 Acry_3020 47 COG3332 COG3332, Uncharacterized conserved protein Function unknown 148259421 Common - Colicin V production protein Acry_0404 7 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 148259859 Common - drug resistance transporter, Bcr/CflA subfamily Acry_0848 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259507 Nonpathogen - hypothetical protein Acry_0491 1 None None None 148260918 Common - Adenylate kinase Acry_1925 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 148261054 Common - hypothetical protein Acry_2062 14 COG5502 COG5502, Uncharacterized conserved protein Function unknown 148259926 Common - outer membrane autotransporter barrel domain Acry_0915 37 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 148259252 Common rpmA 50S ribosomal protein L27 Acry_0232 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 148259990 Common - inositol monophosphatase Acry_0980 144 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148259726 Common - osmosensitive K+ channel signal transduction histidine kinase Acry_0713 217 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 148260861 Common - dethiobiotin synthase Acry_1867 148 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 148260179 Nonpathogen - hypothetical protein Acry_1175 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 148259519 Common - periplasmic binding protein/LacI transcriptional regulator Acry_0503 68 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148260234 Common - molybdenum cofactor biosynthesis protein C Acry_1231 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 148261614 Common - Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family-like protein Acry_2631 93 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 148262021 Common - Putative protein-S-isoprenylcysteine methyltransferase-like protein Acry_3040 16 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 148260158 Common - Xanthine dehydrogenase Acry_1154 105 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 148261387 Common - Methyltransferase type 11 Acry_2401 9 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148259407 Common - Transposase-like protein Acry_0390 4 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 148259046 Common - glycosyl transferase, group 1 Acry_0025 142 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148260618 Common - metallophosphoesterase Acry_1620 32 None None None 148259797 Common - IS66 Orf2 family protein Acry_0785 51 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259749 Common - hypothetical protein Acry_0737 29 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 148261840 Nonpathogen - protein of unknown function DUF1674 Acry_2858 1 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 148259161 Common - K+ potassium transporter Acry_0141 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 148261606 Common - CHAP domain containing protein Acry_2623 12 COG3942 COG3942, Surface antigen General function prediction only 148261405 Nonpathogen - hypothetical protein Acry_2419 1 None None None 148259962 Common - peptidase M50 Acry_0952 76 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 148261156 Common - protoheme IX farnesyltransferase Acry_2165 170 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 148262067 Common - heat shock protein 90 Acry_3087 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 148259138 Common - Squalene/phytoene synthase Acry_0118 97 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 148259727 Common - two component transcriptional regulator, winged helix family Acry_0714 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148259707 Nonpathogen - hypothetical protein Acry_0694 1 None None None 148261658 Common gltX glutamyl-tRNA synthetase Acry_2675 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148260638 Common - Zn-dependent hydrolase of the beta-lactamase fold-like protein Acry_1640 114 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 148259651 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Acry_0638 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 148260047 Common - delta-1-pyrroline-5-carboxylate dehydrogenase Acry_1039 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 148260580 Common - nitrate reductase, beta subunit Acry_1582 149 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 148260282 Common - protein of unknown function DUF195 Acry_1279 104 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 148260456 Common - thioredoxin Acry_1456 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148259592 Common - putative transcriptional regulator, Crp/Fnr family Acry_0576 151 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148260681 Common - major facilitator superfamily MFS_1 Acry_1684 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261139 Common - 3-isopropylmalate dehydratase, small subunit Acry_2148 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 148259261 Common - Phosphoglycerate mutase Acry_0241 130 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 148260256 Common - glucose-methanol-choline oxidoreductase Acry_1253 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 148260228 Common - cytochrome oxidase assembly Acry_1225 44 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 148259483 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Acry_0467 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 148259379 Common - phenylalanyl-tRNA synthetase, alpha subunit Acry_0362 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 148261037 Common - Methyltransferase type 11 Acry_2045 19 None None None 148259806 Common - UvrD/REP helicase Acry_0795 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 148259752 Common - aminotransferase, class I and II Acry_0740 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148262057 Common - protein of unknown function DUF1305 Acry_3077 44 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 148260190 Common - binding-protein-dependent transport systems inner membrane component Acry_1186 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148259992 Common - binding-protein-dependent transport systems inner membrane component Acry_0983 23 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 148261394 Common - Ferredoxin-like protein Acry_2408 45 COG3411 COG3411, Ferredoxin Energy production and conversion 148260074 Common - transcriptional regulator NanR Acry_1066 112 COG2186 FadR, Transcriptional regulators Transcription 148262065 Nonpathogen - MJ0042 family finger-like protein Acry_3085 1 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 148259980 Common - dTMP kinase Acry_0970 211 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 148261407 Common - hypothetical protein Acry_2421 15 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 148261265 Nonpathogen - hypothetical protein Acry_2278 1 None None None 148262084 Common - ribosomal protein S20 Acry_3104 178 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 148261760 Common - transcriptional regulator, LysR family Acry_2777 151 COG0583 LysR, Transcriptional regulator Transcription 148261881 Common - TolB, N-terminal domain protein Acry_2899 147 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 148259383 Common - ATP-dependent metalloprotease FtsH Acry_0366 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 148260350 Common - transcriptional regulator, LysR family Acry_1347 146 COG0583 LysR, Transcriptional regulator Transcription 148259784 Common - hypothetical protein Acry_0772 13 None None None 148260357 Common - PhoH family protein Acry_1354 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 148260909 Common - phosphate ABC transporter, inner membrane subunit PstC Acry_1916 226 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 148259284 Common - Phosphatidylserine decarboxylase Acry_0264 104 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148260120 Common - NADH dehydrogenase (quinone) Acry_1116 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148260487 Common - MscS Mechanosensitive ion channel Acry_1487 214 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148259394 Common - ammonium transporter Acry_0377 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 148259562 Common - glutamine synthetase, catalytic region Acry_0546 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 148259428 Common - tRNA pseudouridine synthase A Acry_0411 230 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 148259452 Common - ABC transporter related Acry_0435 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148261773 Common - Pyrrolo-quinoline quinone Acry_2790 60 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 148261802 Common - pyruvate dehydrogenase subunit beta Acry_2820 220 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 148259975 Common - thiamine biosynthesis protein ThiC Acry_0965 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 148259772 Common flgI flagellar basal body P-ring protein Acry_0760 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 148260931 Common - ribosomal protein L29 Acry_1938 149 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 148260322 Common - sulfate adenylyltransferase, large subunit Acry_1319 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 148260333 Common - phosphoribosylamine--glycine ligase Acry_1330 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 148261108 Common - NusB antitermination factor Acry_2117 33 COG0781 NusB, Transcription termination factor Transcription 148261027 Common - multi-sensor signal transduction histidine kinase Acry_2035 216 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 148259777 Common - hypothetical protein Acry_0765 12 None None None 148260261 Common - MaoC domain protein dehydratase Acry_1258 26 COG2030 MaoC, Acyl dehydratase Lipid metabolism 148259220 Common - heat shock protein Hsp20 Acry_0200 169 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 148260135 Common - cation diffusion facilitator family transporter Acry_1131 159 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 148260331 Common - tryptophan synthase subunit beta Acry_1328 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 148260506 Nonpathogen - hypothetical protein Acry_1506 1 None None None 148260141 Common - ABC transporter related Acry_1137 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 148262076 Common - Extracellular ligand-binding receptor Acry_3096 131 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148261769 Common - membrane bound O-acyl transferase, MBOAT family protein Acry_2786 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 148259730 Common - Transketolase domain protein Acry_0717 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 148259082 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Acry_0061 209 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 148260941 Common - elongation factor Tu Acry_1948 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 148259339 Common - Cupin 2, conserved barrel domain protein Acry_0320 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 148261999 Common - protein of unknown function DUF140 Acry_3017 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 148259097 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_0076 105 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148260461 Nonpathogen - Biopolymer transport protein ExbD/TolR Acry_1461 1 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 148261142 Common - tRNA (guanine-N1)-methyltransferase Acry_2151 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 148259759 Common - argininosuccinate synthase Acry_0747 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 148261070 Common - extracellular solute-binding protein, family 5 Acry_2078 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148261865 Common - LexA repressor Acry_2883 169 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 148261380 Common - iron-containing alcohol dehydrogenase Acry_2394 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 148261495 Nonpathogen - hypothetical protein Acry_2512 2 None None None 148260545 Nonpathogen - hypothetical protein Acry_1545 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 148260015 Common - transcriptional regulator, LysR family Acry_1006 110 COG0583 LysR, Transcriptional regulator Transcription 148260088 Common - fumarylacetoacetase Acry_1081 46 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 148261959 Common - flavoprotein involved in K+ transport-like protein Acry_2977 74 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 148260748 Common - protein of unknown function DUF74 Acry_1752 44 COG0393 COG0393, Uncharacterized conserved protein Function unknown 148259521 Common - Monosaccharide-transporting ATPase Acry_0505 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260182 Common - pantetheine-phosphate adenylyltransferase Acry_1178 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 148259885 Common - hypothetical protein Acry_0874 5 None None None 148261366 Nonpathogen - hypothetical protein Acry_2380 3 None None None 148261952 Common - Glycosyltransferase-like protein Acry_2970 62 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259118 Common - transposase, IS4 family protein Acry_0097 17 None None None 148260856 Common - Galactarate dehydratase Acry_1862 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 148260272 Common - major facilitator superfamily MFS_1 Acry_1269 131 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 148261234 Nonpathogen - hypothetical protein Acry_2247 1 None None None 148259355 Common - Ni/Fe-hydrogenase, b-type cytochrome subunit Acry_0336 58 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 148259822 Common - phage integrase family protein Acry_0811 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148259871 Common - GatB/Yqey domain protein Acry_0860 147 COG1610 COG1610, Uncharacterized conserved protein Function unknown 148259345 Common - hydrogenase assembly chaperone hypC/hupF Acry_0326 52 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 148261593 Common - phenylacetate-CoA oxygenase, PaaI subunit Acry_2610 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 148261785 Common - uroporphyrin-III C-methyltransferase Acry_2802 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 148259351 Common - Rubredoxin-type Fe(Cys)4 protein Acry_0332 108 COG1773 COG1773, Rubredoxin Energy production and conversion 148259890 Nonpathogen - hypothetical protein Acry_0879 1 None None None 148259376 Common - inner-membrane translocator Acry_0359 157 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148259472 Common - FGGY-family pentulose kinase Acry_0456 159 COG1069 AraB, Ribulose kinase Energy production and conversion 148261289 Common - IstB domain protein ATP-binding protein Acry_2302 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148260365 Common - ABC transporter related Acry_1362 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148260974 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Acry_1981 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148259124 Nonpathogen - Tetratricopeptide TPR_2 repeat protein Acry_0104 2 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148260278 Common - glucose-6-phosphate 1-dehydrogenase Acry_1275 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 148260112 Common - proton-translocating NADH-quinone oxidoreductase, chain N Acry_1108 207 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 148260810 Common - AAA ATPase, central domain protein Acry_1816 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 148259315 Common - TonB family protein Acry_0296 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 148260308 Common - WD-40 repeat protein Acry_1305 45 COG2319 COG2319, FOG: WD40 repeat General function prediction only 148260922 Common rpsE 30S ribosomal protein S5 Acry_1929 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 148259997 Common - binding-protein-dependent transport systems inner membrane component Acry_0988 196 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 148259792 Nonpathogen - hypothetical protein Acry_0780 1 None None None 148260766 Common - SirA family protein Acry_1771 21 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148261778 Common - TonB-dependent receptor Acry_2795 121 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148260887 Common - hypothetical protein Acry_1894 4 None None None 148260900 Common smpB SsrA-binding protein Acry_1907 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 148260242 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Acry_1239 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 148260828 Common - toluene tolerance family protein Acry_1834 27 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 148261904 Common - ribosomal protein L35 Acry_2922 107 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 148261079 Common - ImcF domain protein Acry_2088 46 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 148259537 Nonpathogen - hypothetical protein Acry_0521 1 None None None 148260759 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Acry_1764 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 148262030 Nonpathogen - hypothetical protein Acry_3049 7 COG1416 COG1416, Uncharacterized conserved protein Function unknown 148261301 Common - PfkB domain protein Acry_2315 110 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 148259029 Common - PEBP family protein Acry_0008 124 COG1881 COG1881, Phospholipid-binding protein General function prediction only 148261668 Common - Succinylglutamate desuccinylase/aspartoacylase Acry_2685 13 COG3608 COG3608, Predicted deacylase General function prediction only 148259908 Nonpathogen - hypothetical protein Acry_0897 1 None None None 148261713 Common - ABC transporter related Acry_2730 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 148260050 Common - proline iminopeptidase Acry_1042 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148259613 Common - Cephalosporin hydroxylase Acry_0597 21 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 148259156 Common - RND efflux system, outer membrane lipoprotein, NodT family Acry_0136 101 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148261441 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Acry_2456 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260285 Common - transposase, IS4 family protein Acry_1282 59 None None None 148259206 Common - Alanine racemase Acry_0186 130 COG1609 PurR, Transcriptional regulators Transcription 148262036 Common - acetate kinase Acry_3055 161 COG0282 ackA, Acetate kinase Energy production and conversion 148259043 Common - Ribulose-phosphate 3-epimerase Acry_0022 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 148260130 Nonpathogen - hypothetical protein Acry_1126 1 None None None 148260327 Common - 2-alkenal reductase Acry_1324 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 148260735 Common - cytochrome c, class I Acry_1739 7 None None None 148261573 Common - methyl-accepting chemotaxis sensory transducer Acry_2590 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148260874 Common - succinate dehydrogenase, cytochrome b subunit Acry_1880 37 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 148260474 Common fliG flagellar motor switch protein G Acry_1474 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 148260405 Common - tRNA/rRNA methyltransferase (SpoU) Acry_1403 148 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 148261876 Common - transcriptional regulator, XRE family Acry_2894 19 COG1396 HipB, Predicted transcriptional regulators Transcription 148259288 Common - integration host factor, alpha subunit Acry_0268 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148260297 Common - glycosyl transferase, family 2 Acry_1294 45 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148260424 Common - short-chain dehydrogenase/reductase SDR Acry_1422 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261358 Common - Hydroxypyruvate reductase Acry_2372 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 148259054 Nonpathogen - hypothetical protein Acry_0033 1 None None None 148260562 Common - Putative protein-S-isoprenylcysteine methyltransferase-like protein Acry_1564 27 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 148261621 Nonpathogen - hypothetical protein Acry_2638 1 None None None 148259680 Common - helix-turn-helix- domain containing protein, AraC type Acry_0667 106 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 148260843 Common - protocatechuate 3,4-dioxygenase, beta subunit Acry_1849 57 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 148260332 Common trpA tryptophan synthase subunit alpha Acry_1329 210 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 148261183 Common - hypothetical protein Acry_2193 40 COG2267 PldB, Lysophospholipase Lipid metabolism 148259664 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Acry_0651 125 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 148260832 Common - hypothetical protein Acry_1838 15 None None None 148259689 Common - transcriptional regulator, TetR family Acry_0676 45 COG1309 AcrR, Transcriptional regulator Transcription 148261992 Common ectC L-ectoine synthase Acry_3010 35 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 148260573 Common - short-chain dehydrogenase/reductase SDR Acry_1575 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261703 Nonpathogen - hypothetical protein Acry_2720 1 None None None 148260346 Common - large conductance mechanosensitive channel protein Acry_1343 141 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148259914 Common - carboxyl-terminal protease Acry_0903 185 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 148261379 Common - glutamine synthetase, catalytic region Acry_2393 220 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 148259430 Common - hypothetical protein Acry_0413 7 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 148260644 Common - GrpE protein Acry_1647 200 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 148259742 Common - DNA topoisomerase I Acry_0729 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 148260095 Common - flavoprotein involved in K+ transport-like protein Acry_1088 84 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 148260719 Common - formamidopyrimidine-DNA glycosylase Acry_1723 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 148259073 Common - Lipocalin family protein Acry_0052 30 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 148261199 Common - hypothetical protein Acry_2209 27 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261632 Common - efflux transporter, RND family, MFP subunit Acry_2649 126 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148260626 Common - gamma-glutamyltranspeptidase Acry_1628 12 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 148259525 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_0509 114 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148260189 Common - extracellular solute-binding protein, family 5 Acry_1185 170 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148260724 Common - deoxyribodipyrimidine photolyase-related protein Acry_1728 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 148260812 Common - hypothetical protein Acry_1818 5 None None None 148260191 Common - binding-protein-dependent transport systems inner membrane component Acry_1187 208 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148261123 Nonpathogen - flagellar hook-basal body complex protein FliE Acry_2132 1 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 148259878 Common - glycosyl transferase, family 39 Acry_0867 40 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 148259367 Common - high-affinity nickel-transporter Acry_0350 37 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 148259819 Nonpathogen - hypothetical protein Acry_0808 1 None None None 148261520 Common - phosphoribosylformylglycinamidine cyclo-ligase Acry_2537 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 148259931 Common - histone family protein DNA-binding protein Acry_0920 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148259636 Common - methylisocitrate lyase Acry_0622 131 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 148261190 Common - OsmC family protein Acry_2200 5 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148259453 Common - methionine biosynthesis protein MetW Acry_0436 79 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148261628 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Acry_2645 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 148259805 Common - ATP-dependent endonuclease of the OLD family-like protein Acry_0794 35 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 148261132 Common - 60 kDa inner membrane insertion protein Acry_2141 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 148260989 Common - Uncharacterized protein-like protein Acry_1997 28 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 148259645 Common - hypothetical protein Acry_0631 10 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 148260368 Common - Monosaccharide-transporting ATPase Acry_1365 119 COG4158 COG4158, Predicted ABC-type sugar transport system, permease component General function prediction only 148260702 Common - translation elongation factor P Acry_1706 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 148261093 Common - putative transcriptional regulator, Crp/Fnr family Acry_2102 163 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148261962 Nonpathogen - hypothetical protein Acry_2980 5 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 148261947 Common - ATPase involved in chromosome partitioning-like protein Acry_2965 31 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148260806 Common - hypothetical protein Acry_1812 4 None None None 148261779 Common - FAD linked oxidase domain protein Acry_2796 190 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 148260237 Common - anthranilate synthase component I Acry_1234 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 148259791 Common - hypothetical protein Acry_0779 11 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260798 Common - glycosyl transferase, group 1 Acry_1803 171 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259986 Common - glycosyl transferase, family 2 Acry_0976 182 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260866 Common - protein of unknown function DUF125, transmembrane Acry_1872 64 COG1814 COG1814, Uncharacterized membrane protein Function unknown 148260467 Common - 3-dehydroquinate synthase Acry_1467 212 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 148260527 Common - acyl carrier protein Acry_1527 204 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148259235 Common - peptidase M24 Acry_0215 138 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 148259558 Common - spermidine/putrescine ABC transporter ATPase subunit Acry_0542 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 148261386 Common - Cupin 2, conserved barrel domain protein Acry_2400 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 148259940 Common - NADH dehydrogenase subunit I Acry_0929 193 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 148261735 Common - Enoyl-CoA hydratase/isomerase Acry_2752 165 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148260165 Common - amidase, hydantoinase/carbamoylase family Acry_1161 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148259279 Common - Rubrerythrin Acry_0259 23 COG1633 COG1633, Uncharacterized conserved protein Function unknown 148261161 Common - protein of unknown function DUF1058 Acry_2170 38 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 148260380 Common - amidohydrolase 2 Acry_1377 28 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 148259191 Common - Mammalian cell entry related domain protein Acry_0171 101 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 148261635 Common - hemolysin A Acry_2652 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 148261914 Common - inner-membrane translocator Acry_2932 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 148261233 Common secA preprotein translocase subunit SecA Acry_2246 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 148261502 Nonpathogen - hypothetical protein Acry_2519 2 None None None 148260396 Common - acriflavin resistance protein Acry_1394 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148260684 Common - penicillin-binding protein, 1A family Acry_1687 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 148261162 Common - UBA/THIF-type NAD/FAD binding protein Acry_2171 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 148261453 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Acry_2469 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 148259853 Common - transcriptional regulator, LysR family Acry_0842 170 COG0583 LysR, Transcriptional regulator Transcription 148260522 Nonpathogen - hypothetical protein Acry_1522 8 None None None 148261709 Common - Amidase Acry_2726 199 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148260170 Common - Collagen triple helix repeat Acry_1166 16 None None None 148260384 Common - Methane monooxygenase Acry_1381 19 None None None 148261509 Common - hypothetical protein Acry_2526 3 COG5281 COG5281, Phage-related minor tail protein Function unknown 148261071 Common - alpha/beta hydrolase fold Acry_2079 29 COG2267 PldB, Lysophospholipase Lipid metabolism 148261173 Common - glycosyl transferase, family 2 Acry_2183 112 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148261114 Common - Glycine hydroxymethyltransferase Acry_2123 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 148260631 Nonpathogen - hypothetical protein Acry_1633 1 None None None 148261971 Common - carbohydrate kinase, FGGY Acry_2989 101 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148260002 Common - Sarcosine oxidase, delta subunit, heterotetrameric Acry_0993 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 148261347 Common - AMP-dependent synthetase and ligase Acry_2361 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261850 Common - hypothetical protein Acry_2868 2 None None None 148260786 Common - methylmalonate-semialdehyde dehydrogenase Acry_1791 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148261758 Common - integral membrane protein-like protein Acry_2775 26 COG5473 COG5473, Predicted integral membrane protein Function unknown 148259393 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Acry_0376 128 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 148260965 Common - ABC transporter related Acry_1972 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148261145 Common - signal recognition particle protein Acry_2154 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 148261217 Common - amidohydrolase Acry_2229 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 148261930 Common - Peroxidase Acry_2948 208 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148261513 Nonpathogen - hypothetical protein Acry_2530 1 None None None 148261444 Common - putative ABC transporter ATP-binding protein Acry_2460 244 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148260959 Common - peptidase S49 Acry_1966 177 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148261900 Common - protein of unknown function DUF1045 Acry_2918 27 None None None 148259328 Nonpathogen - efflux transporter, RND family, MFP subunit Acry_0309 1 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148260012 Common - Rieske (2Fe-2S) domain protein Acry_1003 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 148261257 Common - FeS assembly protein SufD Acry_2270 176 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 148261101 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Acry_2110 16 COG5135 COG5135, Uncharacterized conserved protein Function unknown 148260290 Common - hypothetical protein Acry_1287 24 None None None 148261534 Common rpmJ 50S ribosomal protein L36 Acry_2551 74 None None None 148259418 Common - adenine phosphoribosyltransferase Acry_0401 184 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 148259364 Common - Nitrate reductase Acry_0345 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148260771 Common - hypothetical protein Acry_1776 6 None None None 148261969 Common - L-rhamnose isomerase Acry_2987 27 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 148261317 Common - hypothetical protein Acry_2331 40 None None None 148259242 Common - protein of unknown function DUF150 Acry_0222 163 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 148261060 Common - major facilitator superfamily MFS_1 Acry_2068 193 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 148260563 Nonpathogen - hypothetical protein Acry_1565 1 None None None 148259069 Common - carbohydrate kinase, YjeF related protein Acry_0048 215 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 148259463 Common - hypothetical protein Acry_0446 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 148259331 Common - integral membrane sensor signal transduction histidine kinase Acry_0312 185 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148260109 Common - Resolvase, N-terminal domain Acry_1104 127 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 148259215 Common - major facilitator superfamily MFS_1 Acry_0195 130 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259830 Common - OsmC family protein Acry_0819 96 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148259723 Common - potassium-transporting ATPase, C subunit Acry_0710 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 148261333 Nonpathogen - hypothetical protein Acry_2347 1 None None None 148259842 Nonpathogen - hypothetical protein Acry_0831 1 None None None 148259947 Common - pantothenate kinase Acry_0936 109 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 148259713 Nonpathogen - hypothetical protein Acry_0700 1 None None None 148260760 Common - ferredoxin Acry_1765 101 COG0633 Fdx, Ferredoxin Energy production and conversion 148260206 Common - ROK family protein Acry_1202 120 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148261096 Common - protein of unknown function DUF482 Acry_2105 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 148261178 Common - acyl-CoA dehydrogenase domain protein Acry_2188 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148261310 Common - short chain dehydrogenase Acry_2324 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261460 Common - protein of unknown function DUF299 Acry_2476 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 148259335 Common - diaminopropionate ammonia-lyase Acry_0316 80 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148261677 Common hisG ATP phosphoribosyltransferase catalytic subunit Acry_2694 203 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 148261339 Common - NAD-dependent epimerase/dehydratase Acry_2353 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148261417 Common - Alanine racemase Acry_2432 127 COG1609 PurR, Transcriptional regulators Transcription 148261849 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2867 188 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 148261080 Common - OmpA/MotB domain protein Acry_2089 126 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 148259766 Common rpsA 30S ribosomal protein S1 Acry_0754 213 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 148259585 Common - Cellulose synthase (UDP-forming) Acry_0569 127 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148261749 Common - Oligopeptidase B Acry_2766 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 148261826 Common - DNA polymerase IV Acry_2844 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 148260929 Common - ribosomal protein L14 Acry_1936 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 148259828 Common - phosphoglucosamine mutase Acry_0817 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 148259092 Common - ComEC/Rec2-related protein Acry_0071 166 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 148261368 Common - oxidoreductase alpha (molybdopterin) subunit Acry_2382 174 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148261290 Common - Integrase, catalytic region Acry_2303 62 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259031 Common - ABC-type molybdate transport system periplasmic component-like protein Acry_0010 25 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 148259298 Nonpathogen - phage integrase family protein Acry_0278 5 None None None 148260021 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Acry_1012 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 148259691 Common - putative transcriptional regulator, GntR family Acry_0678 134 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 148260513 Common - Antibiotic biosynthesis monooxygenase Acry_1513 6 COG1359 COG1359, Uncharacterized conserved protein Function unknown 148262022 Common - oxidoreductase, molybdopterin binding Acry_3041 87 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 148259065 Common - 5-aminolevulinate synthase Acry_0044 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 148261483 Common - endonuclease III Acry_2500 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 148261954 Nonpathogen - hypothetical protein Acry_2972 1 None None None 148260971 Common - oxidoreductase, molybdopterin binding Acry_1978 107 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 148261751 Common - hypothetical protein Acry_2768 3 COG5373 COG5373, Predicted membrane protein Function unknown 148261226 Common - periplasmic binding protein/LacI transcriptional regulator Acry_2239 108 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148260030 Common - Phosphomannomutase Acry_1021 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 148260694 Common - glutathione-dependent formaldehyde-activating, GFA Acry_1698 63 COG3791 COG3791, Uncharacterized conserved protein Function unknown 148261940 Common - two component, sigma54 specific, transcriptional regulator, Fis family Acry_2958 172 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148261249 Common - helix-turn-helix domain protein Acry_2262 4 COG1395 COG1395, Predicted transcriptional regulator Transcription 148259146 Common - hypothetical protein Acry_0126 3 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 148261607 Common - dimethyladenosine transferase Acry_2624 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 148260087 Common - major facilitator superfamily MFS_1 Acry_1080 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148260539 Common - short-chain dehydrogenase/reductase SDR Acry_1539 225 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 148261203 Common - Monosaccharide-transporting ATPase Acry_2213 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260411 Common hslU ATP-dependent protease ATP-binding subunit Acry_1409 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 148259597 Common - protein of unknown function DUF955 Acry_0581 48 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 148261224 Common - Monosaccharide-transporting ATPase Acry_2237 83 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259969 Common - protein of unknown function DUF395, YeeE/YedE Acry_0959 25 COG2391 COG2391, Predicted transporter component General function prediction only 148261001 Common - NUDIX hydrolase Acry_2009 109 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 148259412 Common - H+-transporting two-sector ATPase, B/B' subunit Acry_0395 44 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 148259508 Common - ThiJ/PfpI domain protein Acry_0492 82 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 148260956 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Acry_1963 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 148260495 Common - phosphoribosyltransferase Acry_1495 167 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 148261011 Common - Flp pilus assembly protein ATPase CpaE-like protein Acry_2019 25 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 148259540 Nonpathogen - hypothetical protein Acry_0524 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 148260377 Nonpathogen - hypothetical protein Acry_1374 3 None None None 148260701 Nonpathogen - hypothetical protein Acry_1705 3 None None None 148261069 Common - binding-protein-dependent transport systems inner membrane component Acry_2077 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148261669 Common - CDP-alcohol phosphatidyltransferase Acry_2686 137 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 148260899 Common - oxidoreductase, molybdopterin binding Acry_1906 127 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 148259447 Common - protein of unknown function DUF45 Acry_0430 140 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 148259883 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Acry_0872 165 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 148259200 Common - Uncharacterized protein-like protein Acry_0180 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 148261823 Common - GCN5-related N-acetyltransferase Acry_2841 9 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 148259187 Common - Phosphopyruvate hydratase Acry_0167 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 148261958 Common - Alcohol dehydrogenase, zinc-binding domain protein Acry_2976 190 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 148259543 Common - Uracil-DNA glycosylase superfamily Acry_0527 90 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148260827 Common - 1-deoxy-D-xylulose-5-phosphate synthase Acry_1833 217 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 148259121 Common - transposase, IS4 family protein Acry_0101 45 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148260138 Common - acyltransferase 3 Acry_1134 96 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 148261138 Common - 3-isopropylmalate dehydrogenase Acry_2147 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148261245 Common - 3-oxoacid CoA-transferase, B subunit Acry_2258 98 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 148261281 Nonpathogen - hypothetical protein Acry_2294 1 None None None 148260277 Common - Cof-like hydrolase Acry_1274 129 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 148259524 Common - GDP-mannose 4,6-dehydratase Acry_0508 222 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 148259356 Common - nickel-dependent hydrogenase, large subunit Acry_0337 100 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 148261590 Common - ABC transporter related Acry_2607 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259872 Common - DNA primase Acry_0861 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 148259028 Common - acyl-CoA dehydrogenase domain protein Acry_0007 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148260129 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_1125 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148259811 Common - hypothetical protein Acry_0800 3 None None None 148260581 Common - nitrate reductase molybdenum cofactor assembly chaperone Acry_1583 52 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 148260720 Common - ubiquinone/menaquinone biosynthesis methyltransferase Acry_1724 206 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148259789 Common - hypothetical protein Acry_0777 5 None None None 148260115 Common - NADH-ubiquinone oxidoreductase, chain 4L Acry_1111 92 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 148260323 Common - chorismate synthase Acry_1320 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 148261766 Common - inner-membrane translocator Acry_2783 76 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148262031 Common - protein of unknown function DUF81 Acry_3050 61 COG0730 COG0730, Predicted permeases General function prediction only 148260064 Common - GCN5-related N-acetyltransferase Acry_1056 13 COG0456 RimI, Acetyltransferases General function prediction only 148260305 Common - glycosyl transferase, group 1 Acry_1302 87 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148259660 Common - tartrate dehydrogenase Acry_0647 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148259998 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Acry_0989 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 148261288 Common - hypothetical protein Acry_2301 16 None None None 148261710 Common - biotin carboxylation domain protein Acry_2727 227 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 148261907 Common - metallophosphoesterase Acry_2925 66 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 148260390 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Acry_1387 122 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 148260923 Common - ribosomal protein L18 Acry_1930 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 148260859 Common - inner-membrane translocator Acry_1865 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148259371 Common - rfaE bifunctional protein Acry_0354 120 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 148261683 Common - radical SAM enzyme, Cfr family Acry_2700 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 148260053 Common - hypothetical protein Acry_1045 12 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 148260851 Common - PfkB domain protein Acry_1857 85 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148261457 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Acry_2473 109 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 148260147 Common - Uncharacterized protein-like protein Acry_1143 21 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 148261373 Common - methyl-accepting chemotaxis sensory transducer Acry_2387 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148261271 Nonpathogen - hypothetical protein Acry_2284 1 None None None 148261537 Common - ribosome recycling factor Acry_2554 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 148261761 Common - protein of unknown function DUF849 Acry_2778 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 148260351 Common - UDP-glucose 6-dehydrogenase Acry_1348 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 148260715 Common - multiple antibiotic resistance (MarC)-related protein Acry_1719 156 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 148261270 Nonpathogen - hypothetical protein Acry_2283 1 None None None 148260944 Common - DNA-directed RNA polymerase subunit beta' Acry_1951 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 148261557 Common - glycerol-3-phosphate dehydrogenase Acry_2574 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148259462 Common - PTS system fructose subfamily IIA component Acry_0445 70 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 148259110 Common - putative transcriptional regulator, MerR family Acry_0089 121 COG0789 SoxR, Predicted transcriptional regulators Transcription 148259821 Common - hypothetical protein Acry_0810 9 None None None 148259679 Common - Carbonate dehydratase Acry_0666 141 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 148259520 Common - ABC transporter related Acry_0504 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148260142 Common - inner-membrane translocator Acry_1138 113 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259260 Common - Glutathione S-transferase, N-terminal domain Acry_0240 94 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148259840 Common - pyridoxamine 5'-phosphate oxidase Acry_0829 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 148261911 Common - ABC transporter related Acry_2929 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148259352 Common - HupH hydrogenase expression protein Acry_0333 19 None None None 148259648 Nonpathogen - hypothetical protein Acry_0635 1 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 148259900 Nonpathogen - hypothetical protein Acry_0889 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 148260745 Common - urocanate hydratase Acry_1749 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 148260648 Nonpathogen - hypothetical protein Acry_1651 6 None None None 148260793 Common - hydroxylamine reductase Acry_1798 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 148259438 Common - hypothetical protein Acry_0421 35 None None None 148259094 Common - sugar transferase Acry_0073 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 148260264 Common - ferredoxin Acry_1261 158 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 148260503 Nonpathogen - hypothetical protein Acry_1503 1 None None None 148260336 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Acry_1333 160 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148260945 Common rpoB DNA-directed RNA polymerase subunit beta Acry_1952 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 148261731 Common - export-related chaperone CsaA Acry_2748 144 COG0073 ARC1, EMAP domain General function prediction only 148259594 Common - PAS/PAC sensor hybrid histidine kinase Acry_0578 196 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 148259758 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Acry_0746 160 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148260809 Common - hypothetical protein Acry_1815 37 None None None 148260776 Common - type I secretion outer membrane protein, TolC family Acry_1781 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148260552 Nonpathogen - hypothetical protein Acry_1554 2 None None None 148260878 Common - two component transcriptional regulator, winged helix family Acry_1884 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148259250 Common - Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components-like protein Acry_0230 50 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259262 Common - iron-containing alcohol dehydrogenase Acry_0242 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 148259516 Common - Rhodanese domain protein Acry_0500 136 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148261728 Common - ABC transporter related Acry_2745 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 148260247 Common - diguanylate phosphodiesterase Acry_1244 157 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 148261146 Common - NAD(P)(+) transhydrogenase (AB-specific) Acry_2155 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 148261478 Common - aminotransferase, class I and II Acry_2494 233 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148261295 Nonpathogen - hypothetical protein Acry_2308 1 None None None 148261450 Common - heavy metal translocating P-type ATPase Acry_2466 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 148261496 Nonpathogen - hypothetical protein Acry_2513 1 None None None 148260727 Common - citrate synthase I Acry_1731 194 COG0372 GltA, Citrate synthase Energy production and conversion 148260544 Nonpathogen - hypothetical protein Acry_1544 2 None None None 148260911 Common - YbaK/prolyl-tRNA synthetase associated region Acry_1918 66 COG2606 EbsC, Uncharacterized conserved protein Function unknown 148259576 Common - glycerophosphoryl diester phosphodiesterase Acry_0560 106 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 148260962 Common - anti-ECFsigma factor, ChrR Acry_1969 31 COG3806 ChrR, Transcriptional activator Transcription 148260213 Common - DNA repair protein RecO Acry_1209 19 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 148261488 Common - Usg family protein Acry_2505 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 148261615 Common - heat shock protein Hsp20 Acry_2632 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 148259932 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Acry_0921 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 148259068 Common - Cobyrinic acid a,c-diamide synthase Acry_0047 117 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148259501 Common - ABC transporter related Acry_0485 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148260633 Common - cytochrome bd ubiquinol oxidase, subunit I Acry_1635 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 148259180 Common - hypothetical protein Acry_0160 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 148259360 Common - UbiA prenyltransferase Acry_0341 104 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 148259678 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Acry_0665 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 148260770 Common - nitrogen-fixing NifU domain protein Acry_1775 113 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 148259949 Common - acyltransferase 3 Acry_0938 32 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 148261038 Common uvrA excinuclease ABC subunit A Acry_2046 235 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 148261630 Common - Pyridoxal-dependent decarboxylase Acry_2647 71 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 148261603 Common - Mg chelatase, subunit ChlI Acry_2620 188 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 148260222 Common - ABC transporter domain protein Acry_1219 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 148262014 Common - alkylhydroperoxidase like protein, AhpD family Acry_3032 44 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 148261228 Common - Peptidoglycan glycosyltransferase Acry_2241 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148259290 Common - fatty acid/phospholipid synthesis protein Acry_0270 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 148260485 Common - haloacid dehalogenase, type II Acry_1485 23 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 148261131 Common - protein of unknown function DUF37 Acry_2140 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 148259532 Common - protein of unknown function DUF1130 Acry_0516 37 COG5483 COG5483, Uncharacterized conserved protein Function unknown 148260871 Common - 4-hydroxybenzoate polyprenyl transferase Acry_1877 151 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 148260787 Common - transcriptional regulator, LysR family Acry_1792 94 COG0583 LysR, Transcriptional regulator Transcription 148261213 Nonpathogen - hypothetical protein Acry_2225 1 None None None 148259953 Common - Alpha/beta hydrolase fold-3 domain protein Acry_0942 140 COG0657 Aes, Esterase/lipase Lipid metabolism 148261519 Common - protein of unknown function UPF0118 Acry_2536 186 COG0628 PerM, Predicted permease General function prediction only 148259061 Common - lipid-A-disaccharide synthase Acry_0040 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 148261439 Nonpathogen - hypothetical protein Acry_2454 1 None None None 148259378 Common pheT phenylalanyl-tRNA synthetase subunit beta Acry_0361 214 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 148259605 Nonpathogen - hypothetical protein Acry_0589 1 None None None 148260653 Common - binding-protein-dependent transport systems inner membrane component Acry_1656 138 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148260372 Common - Serine--glyoxylate transaminase Acry_1369 155 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 148261543 Common - cysteine synthase A Acry_2560 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 148261463 Common - hypothetical protein Acry_2479 4 None None None 148259667 Nonpathogen - hypothetical protein Acry_0654 1 None None None 148260486 Nonpathogen - hypothetical protein Acry_1486 1 None None None 148259172 Nonpathogen - Disulphide bond formation protein DsbB Acry_0152 6 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 148261356 Common - 4-oxalocrotonate tautomerase Acry_2370 8 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 148261401 Common - glycosyl transferase, family 4 Acry_2415 96 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148259234 Common - cytochrome c-type biogenesis protein CcmB Acry_0214 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 148260241 Common - CTP synthetase Acry_1238 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 148259929 Common clpX ATP-dependent protease ATP-binding subunit Acry_0918 226 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 148260650 Common - ribonuclease H Acry_1653 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 148260316 Common - cell shape determining protein, MreB/Mrl family Acry_1313 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 148262056 Common - protein of unknown function DUF879 Acry_3076 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 148259638 Common - Enoyl-CoA hydratase/isomerase Acry_0624 128 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148259404 Common - glycosyltransferase sugar-binding region containing DXD motif Acry_0387 8 COG3774 OCH1, Mannosyltransferase OCH1 and related enzymes Cell envelope biogenesis, outer membrane 148259457 Common - Prephenate dehydrogenase Acry_0440 168 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 148261064 Common - FAD dependent oxidoreductase Acry_2072 95 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148260404 Common - Ferritin, Dps family protein Acry_1402 32 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 148259773 Nonpathogen - hypothetical protein Acry_0761 8 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 148261770 Nonpathogen - hypothetical protein Acry_2787 1 None None None 148262077 Common - TonB-dependent receptor, plug Acry_3097 125 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 148260296 Nonpathogen - hypothetical protein Acry_1293 1 None None None 148259482 Common - phosphogluconate dehydratase Acry_0466 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148259751 Common - ribonucleotide-diphosphate reductase subunit alpha Acry_0739 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 148261395 Common - protein of unknown function DUF255 Acry_2409 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 148260436 Common - hypothetical protein Acry_1435 11 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 148260619 Common - dihydrolipoamide dehydrogenase Acry_1621 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148261838 Common - cytochrome C biogenesis protein Acry_2856 90 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 148261694 Common - chemotaxis-specific methylesterase Acry_2711 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 148261309 Common - hypothetical protein Acry_2323 2 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 148259642 Common - DNA mismatch repair protein MutL Acry_0628 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 148261622 Common - DEAD/DEAH box helicase domain protein Acry_2639 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148261856 Nonpathogen - hypothetical protein Acry_2874 2 None None None 148261055 Nonpathogen - Patatin Acry_2063 1 None None None 148259294 Common - succinic semialdehyde dehydrogenase Acry_0274 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148261941 Nonpathogen - Tetratricopeptide TPR_4 Acry_2959 18 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 148261028 Common - two component, sigma54 specific, transcriptional regulator, Fis family Acry_2036 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148259731 Common - Transketolase, central region Acry_0718 230 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 148260312 Common - major facilitator superfamily MFS_1 Acry_1309 100 None None None 148259943 Common - proton-translocating NADH-quinone oxidoreductase, chain L Acry_0932 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 148259081 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Acry_0060 215 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148259654 Common - hypothetical protein Acry_0641 16 None None None 148261657 Nonpathogen - hypothetical protein Acry_2674 1 None None None 148261343 Common - SOUL heme-binding protein Acry_2357 26 None None None 148259199 Common - protein of unknown function DUF1244 Acry_0179 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 148260569 Nonpathogen - hypothetical protein Acry_1571 1 None None None 148260271 Common - MmgE/PrpD family protein Acry_1268 77 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 148261279 Nonpathogen - hypothetical protein Acry_2292 1 None None None 148259897 Common - hypothetical protein Acry_0886 2 None None None 148260939 Common rplC 50S ribosomal protein L3 Acry_1946 233 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 148261721 Common - dihydrodipicolinate synthetase Acry_2738 135 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148260293 Nonpathogen - hypothetical protein Acry_1290 1 None None None 148262001 Common - adenylosuccinate lyase Acry_3019 237 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 148261611 Common - permease YjgP/YjgQ family protein Acry_2628 86 COG0795 COG0795, Predicted permeases General function prediction only 148261984 Common - binding-protein-dependent transport systems inner membrane component Acry_3002 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148261083 Common - putative FHA domain containing protein Acry_2092 23 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 148259239 Common - 5,10-methylenetetrahydrofolate reductase Acry_0219 138 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 148259117 Common - hypothetical protein Acry_0096 6 None None None 148261427 Common - putative transcriptional regulator, AsnC family Acry_2442 149 COG1522 Lrp, Transcriptional regulators Transcription 148259253 Common obgE GTPase ObgE Acry_0233 249 COG0536 Obg, Predicted GTPase General function prediction only 148261051 Common - ribose-phosphate pyrophosphokinase Acry_2059 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 148262045 Common - hypothetical protein Acry_3064 4 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 148261095 Common - aminopeptidase N Acry_2104 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 148259721 Common - potassium-transporting ATPase, A subunit Acry_0708 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 148259799 Common - hypothetical protein Acry_0787 55 None None None 148259534 Common - hypothetical protein Acry_0518 7 None None None 148261596 Nonpathogen - hypothetical protein Acry_2613 1 None None None 148261895 Common - phosphonate metabolism Acry_2913 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 148259564 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Acry_0548 166 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 148260025 Common - hypothetical protein Acry_1016 31 None None None 148260726 Common - putative phosphohistidine phosphatase, SixA Acry_1730 27 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 148260977 Common - protein of unknown function DUF937 Acry_1984 17 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 148261449 Common - Heavy metal transport/detoxification protein Acry_2465 11 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148261784 Common - flavodoxin/nitric oxide synthase Acry_2801 97 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 148261300 Common - thiamine pyrophosphate enzyme, central region Acry_2314 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 148261771 Common - nucleoside 2-deoxyribosyltransferase Acry_2788 16 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 148261586 Common - short-chain dehydrogenase/reductase SDR Acry_2603 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261081 Common - protein of unknown function DUF876 Acry_2090 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 148260125 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Acry_1121 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 148260441 Common - fumarate lyase Acry_1440 200 COG0114 FumC, Fumarase Energy production and conversion 148259336 Common - ABC-type sugar transport system periplasmic component-like protein Acry_0317 14 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259812 Common - hypothetical protein Acry_0801 5 None None None 148260821 Common - hypothetical protein Acry_1827 4 None None None 148259637 Common - acyl-CoA dehydrogenase domain protein Acry_0623 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148259405 Common - ribonuclease, Rne/Rng family Acry_0388 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 148259181 Common mtnA methylthioribose-1-phosphate isomerase Acry_0161 131 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 148260054 Common - dihydroxy-acid dehydratase Acry_1046 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148261229 Common - transcriptional regulator, GntR family Acry_2242 126 COG1802 GntR, Transcriptional regulators Transcription 148260587 Common - Alanine racemase Acry_1589 111 COG1609 PurR, Transcriptional regulators Transcription 148260183 Common - DNA gyrase subunit A Acry_1179 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 148259419 Common - hypothetical protein Acry_0402 8 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 148261432 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Acry_2447 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 148259569 Common - ABC transporter, transmembrane region, type 1 Acry_0553 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148261267 Nonpathogen - bacteriochlorophyll 4-vinyl reductase Acry_2280 8 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 148260625 Nonpathogen - hypothetical protein Acry_1627 1 None None None 148259034 Common - hypothetical protein Acry_0013 4 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 148259699 Common - PfkB domain protein Acry_0686 49 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148260444 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Acry_1443 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 148260412 Common - ATP-dependent protease peptidase subunit Acry_1410 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 148261074 Common - Paraquat-inducible protein A Acry_2083 53 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 148260354 Common - Lipopolysaccharide biosynthesis protein-like protein Acry_1351 16 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 148261892 Common - major facilitator superfamily MFS_1 Acry_2910 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261746 Common - DSBA oxidoreductase Acry_2763 45 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 148260166 Common - peptidase M20 Acry_1162 198 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148259765 Nonpathogen - hypothetical protein Acry_0753 1 None None None 148260512 Common - ribosomal protein S6 Acry_1512 191 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 148261246 Common - 4-aminobutyrate aminotransferase Acry_2259 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 148259827 Common - dihydropteroate synthase Acry_0816 215 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 148260896 Common - glycosyl transferase, family 39 Acry_1903 24 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 148261960 Nonpathogen - TadE family protein Acry_2978 10 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 148259889 Nonpathogen - hypothetical protein Acry_0878 1 None None None 148260538 Nonpathogen - hypothetical protein Acry_1538 1 None None None 148260695 Common - hypothetical protein Acry_1699 6 None None None 148259192 Common - hypothetical protein Acry_0172 7 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 148260765 Common - transcriptional regulator, MucR family Acry_1770 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 148259159 Common - MltA domain protein Acry_0139 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 148259700 Nonpathogen - hypothetical protein Acry_0687 2 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 148261346 Common - ferric uptake regulator, Fur family Acry_2360 80 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 148261824 Common - putative cold-shock DNA-binding domain protein Acry_2842 180 COG1278 CspC, Cold shock proteins Transcription 148259165 Common - protein of unknown function DUF6, transmembrane Acry_0145 84 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 148259064 Common - Gluconate 2-dehydrogenase (acceptor) Acry_0043 75 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 148260464 Common - cytochrome B561 Acry_1464 85 COG3038 CybB, Cytochrome B561 Energy production and conversion 148261524 Common - acetylornithine and succinylornithine aminotransferase Acry_2541 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 148259320 Common - protein of unknown function DUF214 Acry_0301 43 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 148259056 Common - hypothetical protein Acry_0035 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148261681 Nonpathogen - hypothetical protein Acry_2698 1 None None None 148261924 Common - methyltransferase FkbM family Acry_2942 14 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148260475 Common - flagellar M-ring protein FliF Acry_1475 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 148260634 Common - Beta tubulin, autoregulation binding site Acry_1636 246 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148261514 Nonpathogen - hypothetical protein Acry_2531 1 None None None 148261979 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Acry_2997 33 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148260005 Common - L-serine dehydratase 1 Acry_0996 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 148261357 Common - hypothetical protein Acry_2371 3 None None None 148261334 Common - phage integrase family protein Acry_2348 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148261182 Common - S-adenosylmethionine decarboxylase related Acry_2192 73 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 148259896 Common - general secretion pathway protein D Acry_0885 141 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 148260955 Nonpathogen - hypothetical protein Acry_1962 1 None None None 148261750 Common - Formate--tetrahydrofolate ligase Acry_2767 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 148261981 Common - uncharacterized peroxidase-related enzyme Acry_2999 70 COG2128 COG2128, Uncharacterized conserved protein Function unknown 148259265 Common - Methyltransferase type 11 Acry_0245 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148260932 Common rplP 50S ribosomal protein L16 Acry_1939 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 148259179 Common - Uncharacterized protein-like protein Acry_0159 23 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 148259332 Common - putative transcriptional regulator, XRE family Acry_0313 41 COG1396 HipB, Predicted transcriptional regulators Transcription 148260230 Common - Lysine exporter protein (LYSE/YGGA) Acry_1227 82 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 148261935 Common - Na+/solute symporter Acry_2953 83 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148260123 Common - NADH-quinone oxidoreductase, B subunit Acry_1119 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 148259245 Common infB translation initiation factor IF-2 Acry_0225 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 148259173 Common - Ubiquinone biosynthesis protein COQ7 Acry_0153 28 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 148261283 Common - hypothetical protein Acry_2296 4 None None None 148261549 Common - extracellular solute-binding protein, family 1 Acry_2566 42 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148261675 Common - translation initiation factor IF-1 Acry_2692 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 148259716 Nonpathogen - hypothetical protein Acry_0703 1 None None None 148259216 Common - dihydrodipicolinate synthetase Acry_0196 216 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148260010 Common - transcriptional regulator, AraC family Acry_1001 111 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 148260092 Common - Uncharacterized protein-like protein Acry_1085 21 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 148259395 Common - cell divisionFtsK/SpoIIIE Acry_0378 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 148259469 Common - major facilitator superfamily MFS_1 Acry_0452 94 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 148261757 Common - chromosome replication initiation inhibitor protein Acry_2774 68 COG0583 LysR, Transcriptional regulator Transcription 148260564 Nonpathogen - hypothetical protein Acry_1566 1 None None None 148260993 Common - NUDIX hydrolase Acry_2001 104 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 148261059 Common - diguanylate cyclase/phosphodiesterase Acry_2067 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148261564 Common - short-chain dehydrogenase/reductase SDR Acry_2581 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148260663 Common - Glutamate synthase (ferredoxin) Acry_1666 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 148259074 Common - Acid phosphatase Acry_0053 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148261122 Common - export protein FliQ, family 3 Acry_2131 8 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 148261374 Common - Glutathione S-transferase, N-terminal domain Acry_2388 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148259624 Common - protein of unknown function DUF190 Acry_0610 51 COG1993 COG1993, Uncharacterized conserved protein Function unknown 148259776 Common - PAS/PAC sensor hybrid histidine kinase Acry_0764 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148261624 Common - Alcohol dehydrogenase GroES domain protein Acry_2641 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 148261536 Common - uridylate kinase Acry_2553 241 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 148260019 Common - PTSINtr with GAF domain, PtsP Acry_1010 215 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 148260983 Common - cell division topological specificity factor MinE Acry_1990 71 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 148260383 Common - oxidoreductase FAD/NAD(P)-binding domain protein Acry_1380 173 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 148260075 Common - Ribulose-bisphosphate carboxylase Acry_1067 66 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 148259963 Common - chromosome segregation and condensation protein ScpA Acry_0953 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 148259899 Common - Fimbrial assembly family protein Acry_0888 2 None None None 148259236 Nonpathogen - protein of unknown function DUF1127 Acry_0216 1 None None None 148260065 Common - Electron-transferring-flavoprotein dehydrogenase Acry_1057 114 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 148259697 Common - polar amino acid ABC transporter, inner membrane subunit Acry_0684 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 148260205 Common - SirA family protein Acry_1201 52 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148261127 Common - integral membrane sensor signal transduction histidine kinase Acry_2136 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148260369 Common - periplasmic binding protein/LacI transcriptional regulator Acry_1366 84 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259584 Common - glycoside hydrolase, family 3 domain protein Acry_0568 101 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 148259053 Common - hypothetical protein Acry_0032 15 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 148260676 Common - ATP synthase F1, alpha subunit Acry_1679 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 148259979 Common - Rare lipoprotein A Acry_0969 132 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 148261452 Common - dihydrodipicolinate synthetase Acry_2468 154 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148259760 Nonpathogen - TonB family protein Acry_0748 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 148260492 Common - methionine aminopeptidase, type I Acry_1492 243 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 148261398 Common - TPR repeat-containing protein Acry_2412 59 COG0457 NrfG, FOG: TPR repeat General function prediction only 148261523 Common - ornithine carbamoyltransferase Acry_2540 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 148260221 Common - glycosyl transferase, family 2 Acry_1218 40 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148260239 Common - Triose-phosphate isomerase Acry_1236 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 148261163 Common - Dioxygenase related to 2-nitropropane dioxygenase-like protein Acry_2173 47 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 148259041 Common - apolipoprotein N-acyltransferase Acry_0020 157 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 148261261 Common - phosphoglycolate phosphatase Acry_2274 197 COG0546 Gph, Predicted phosphatases General function prediction only 148260686 Common - HpcH/HpaI aldolase Acry_1689 57 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 148259850 Common - formate dehydrogenase, alpha subunit Acry_0839 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 148259509 Common - transcriptional regulator, AraC family Acry_0493 140 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 148259978 Common - lytic murein transglycosylase Acry_0968 101 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 148260850 Common - amidohydrolase 2 Acry_1856 40 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 148260108 Nonpathogen - hypothetical protein Acry_1101 1 None None None 148260570 Common - acyltransferase 3 Acry_1572 13 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 148259454 Common metX homoserine O-acetyltransferase Acry_0437 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 148260891 Common - ABC transporter related Acry_1898 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 148260750 Common - transcription-repair coupling factor Acry_1754 214 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 148259983 Common fliM flagellar motor switch protein FliM Acry_0973 106 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 148260176 Nonpathogen - hypothetical protein Acry_1172 1 None None None 148259478 Common - ABC transporter related Acry_0462 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148259026 Common - acetyl-CoA acetyltransferase Acry_0005 182 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 148259684 Common - AMP-dependent synthetase and ligase Acry_0671 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148261576 Common - inner-membrane translocator Acry_2593 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148261872 Common - diguanylate cyclase/phosphodiesterase Acry_2890 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 148262037 Common - putative adenylate/guanylate cyclase Acry_3056 64 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 148259515 Common - protein of unknown function DUF395, YeeE/YedE Acry_0499 35 None None None 148260576 Common - aldo/keto reductase Acry_1578 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148261214 Nonpathogen - hypothetical protein Acry_2226 5 None None None 148261862 Common - putative signal-transduction protein with CBS domains Acry_2880 130 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 148260269 Common - protein of unknown function DUF453 Acry_1266 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 148261137 Common - glycosyl transferase, family 2 Acry_2146 130 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 148260027 Common - CHAP domain containing protein Acry_1018 12 COG3942 COG3942, Surface antigen General function prediction only 148259278 Common - sulfotransferase Acry_0258 30 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 148262044 Common - malate dehydrogenase Acry_3063 106 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 148261326 Common - protein of unknown function DUF1501 Acry_2340 41 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 148259225 Common - glycosyl transferase, group 1 Acry_0205 202 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261442 Nonpathogen - hypothetical protein Acry_2458 2 None None None 148261048 Common - protein of unknown function DUF445 Acry_2056 49 COG2733 COG2733, Predicted membrane protein Function unknown 148261832 Common - protein of unknown function DUF55 Acry_2850 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 148259860 Nonpathogen - protein of unknown function DUF202 Acry_0849 10 COG2149 COG2149, Predicted membrane protein Function unknown 148259920 Common - threonine dehydratase Acry_0909 214 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148260153 Common - permease for cytosine/purines, uracil, thiamine, allantoin Acry_1149 49 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 148260038 Common - hypothetical protein Acry_1030 28 None None None 148260246 Common - malate synthase G Acry_1243 67 COG2225 AceB, Malate synthase Energy production and conversion 148261113 Common - ATP-cone domain protein Acry_2122 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 148261903 Common - glycosyl transferase, family 2 Acry_2921 92 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148259411 Common - H+-transporting two-sector ATPase, B/B' subunit Acry_0394 18 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 148259093 Common - glycosyl transferase, family 2 Acry_0072 21 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148259972 Common - thiazole biosynthesis family protein Acry_0962 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 148261574 Common - Gluconolactonase Acry_2591 79 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 148260588 Common - Alcohol dehydrogenase GroES domain protein Acry_1590 175 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 148261250 Common - Rhodanese domain protein Acry_2263 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148259209 Common - PTS system, fructose subfamily, IIC subunit Acry_0189 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 148260844 Common - 4-hydroxybenzoate 3-monooxygenase Acry_1850 48 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 148261535 Common - aminotransferase, class IV Acry_2552 175 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 148259681 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_0668 105 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148260904 Common - CinA domain protein Acry_1911 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 148261276 Common - malic enzyme Acry_2289 215 COG0281 SfcA, Malic enzyme Energy production and conversion 148261732 Common - Gamma-glutamyltransferase Acry_2749 146 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 148259359 Common - cyclase/dehydrase Acry_0340 36 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 148259858 Common - peptidase C26 Acry_0847 115 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 148260543 Common - nicotinate-nucleotide pyrophosphorylase Acry_1543 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 148259880 Common - electron transport protein SCO1/SenC Acry_0869 103 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 148259586 Common - endo-1,4-D-glucanase Acry_0570 29 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 148259238 Common - UvrD/REP helicase Acry_0218 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 148259158 Common - import inner membrane translocase, subunit Tim44 Acry_0138 48 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 148259385 Common - Enoyl-CoA hydratase/isomerase Acry_0368 132 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 148259493 Common - phenylacetate-CoA ligase Acry_0477 115 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 148260137 Nonpathogen - hypothetical protein Acry_1133 1 None None None 148260240 Nonpathogen - preprotein translocase, SecG subunit Acry_1237 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 148259277 Common - TPR repeat-containing protein Acry_0257 46 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 148259868 Common - acyl-CoA dehydrogenase domain protein Acry_0857 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148261902 Common - transcriptional regulator, GntR family Acry_2920 102 COG2188 PhnF, Transcriptional regulators Transcription 148261950 Common - polysaccharide deacetylase Acry_2968 49 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 148260013 Common - transcriptional regulator, AraC family Acry_1004 99 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 148259323 Common - CrcB protein Acry_0304 178 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 148260647 Common - hypothetical protein Acry_1650 8 None None None 148260167 Common - Chitin deacetylase Acry_1163 54 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 148260943 Common rpsL 30S ribosomal protein S12 Acry_1950 245 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 148259296 Nonpathogen - hypothetical protein Acry_0276 1 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148260086 Common - hypothetical protein Acry_1079 3 None None None 148261470 Nonpathogen - hypothetical protein Acry_2486 1 None None None 148260263 Common fadE acyl-CoA dehydrogenase Acry_1260 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148259757 Common - argininosuccinate lyase Acry_0745 221 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 148259084 Common murG N-acetylglucosaminyl transferase Acry_0063 205 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 148260335 Common - Uncharacterized protein-like protein Acry_1332 17 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 148261556 Common - L-fuculose-phosphate aldolase Acry_2573 134 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148259779 Common - conserved hypothetical protein 245 Acry_0767 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 148260352 Common - Methyltransferase type 11 Acry_1349 47 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148259025 Common - putative transcriptional regulator, MerR family Acry_0004 130 COG0789 SoxR, Predicted transcriptional regulators Transcription 148260504 Common - DNA polymerase I Acry_1504 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 148260746 Common - transcriptional regulator, GntR family Acry_1750 126 COG2188 PhnF, Transcriptional regulators Transcription 148259820 Nonpathogen - hypothetical protein Acry_0809 4 None None None 148260967 Nonpathogen - hypothetical protein Acry_1974 1 None None None 148259369 Common - hypothetical protein Acry_0352 6 None None None 148260148 Common - transcriptional regulator, DeoR family Acry_1144 108 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148259560 Common - putative transcriptional regulator, XRE family Acry_0544 80 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 148259901 Nonpathogen - hypothetical protein Acry_0890 1 None None None 148260808 Common - CRISPR-associated helicase Cas3 Acry_1814 60 COG1203 COG1203, Predicted helicases General function prediction only 148260885 Common - uracil phosphoribosyltransferase Acry_1892 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 148259875 Common - pseudouridine synthase Acry_0864 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148261007 Common - RNA polymerase factor sigma-54 Acry_2015 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 148259396 Nonpathogen - hypothetical protein Acry_0379 3 None None None 148262039 Common - nitrogen regulatory protein P-II Acry_3058 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 148260656 Common - Alcohol dehydrogenase GroES domain protein Acry_1659 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 148260858 Common - ABC transporter related Acry_1864 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148260773 Common - Hydroxyacylglutathione hydrolase Acry_1778 131 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148259470 Common - outer membrane autotransporter barrel domain Acry_0453 90 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 148260223 Common - transketolase Acry_1220 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 148261382 Common dnaE DNA polymerase III subunit alpha Acry_2396 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 148260551 Common - diguanylate cyclase with PAS/PAC sensor Acry_1553 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148261143 Common - 16S rRNA processing protein RimM Acry_2152 54 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 148259781 Common - hypothetical protein Acry_0769 141 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148259254 Common - gamma-glutamyl kinase Acry_0234 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 148260116 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Acry_1112 33 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 148259353 Common - hydrogenase-1 expression HyaE Acry_0334 12 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148261377 Common - amino acid permease-associated region Acry_2391 120 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 148260391 Common - hypothetical protein Acry_1388 44 None None None 148261475 Nonpathogen - hypothetical protein Acry_2491 1 None None None 148260912 Common - Uncharacterized relative of glutathione S-transferase MAPEG superfamily-like protein Acry_1919 7 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 148261906 Common - glycosyl transferase, group 1 Acry_2924 169 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148260780 Common - peptidase U62, modulator of DNA gyrase Acry_1785 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 148261967 Common - ABC-type sugar transport system periplasmic component-like protein Acry_2985 67 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259357 Common - hydrogenase (NiFe) small subunit HydA Acry_0338 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 148262046 Nonpathogen - hypothetical protein Acry_3065 1 None None None 148259201 Common - delta-aminolevulinic acid dehydratase Acry_0181 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 148261811 Common - aldo/keto reductase Acry_2829 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148260898 Common - Redoxin domain protein Acry_1905 93 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148260110 Common - transposase Tn3 family protein Acry_1105 55 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 148260159 Common - molybdopterin dehydrogenase, FAD-binding Acry_1155 123 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 148261661 Nonpathogen - hypothetical protein Acry_2678 1 None None None 148261595 Common - phenylacetate-CoA oxygenase/reductase, PaaK subunit Acry_2612 132 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 148261957 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Acry_2975 176 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 148259744 Common - dihydroorotase, multifunctional complex type Acry_0732 196 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 148259911 Common - Carboxymethylenebutenolidase Acry_0900 90 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 148260839 Common - 3-oxoacid CoA-transferase, B subunit Acry_1845 94 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 148259848 Common - hypothetical protein Acry_0837 20 None None None 148260378 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Acry_1375 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 148260870 Common - protein of unknown function DUF558 Acry_1876 171 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 148260063 Common - Dihydrodipicolinate reductase Acry_1055 209 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 148260306 Common - hypothetical protein Acry_1303 4 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 148260826 Common - hydroxymethylbutenyl pyrophosphate reductase Acry_1832 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 148259122 Common - aminotransferase, class I and II Acry_0102 235 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148262032 Nonpathogen - Tetratricopeptide TPR_4 Acry_3051 8 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148260768 Common - peptidase M22, glycoprotease Acry_1773 122 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 148259370 Common - Hsp33 protein Acry_0353 121 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 148260924 Common rplF 50S ribosomal protein L6 Acry_1931 233 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 148259873 Common - RNA polymerase sigma factor RpoD Acry_0862 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148259027 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Acry_0006 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 148261098 Common - CsbD family protein Acry_2107 11 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 148261711 Common - hypothetical protein Acry_2728 55 COG3665 COG3665, Uncharacterized conserved protein Function unknown 148259882 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Acry_0871 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148261068 Common - binding-protein-dependent transport systems inner membrane component Acry_2076 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148261409 Common - hypothetical protein Acry_2423 18 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 148260434 Common - Polyprenyl synthetase Acry_1432 239 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148259539 Nonpathogen - hypothetical protein Acry_0523 1 COG3774 OCH1, Mannosyltransferase OCH1 and related enzymes Cell envelope biogenesis, outer membrane 148260596 Common - General substrate transporter Acry_1598 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261480 Common - MiaB-like tRNA modifying enzyme Acry_2497 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148261859 Common - PfkB domain protein Acry_2877 118 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148259732 Common - TRAP dicarboxylate transporter, DctP subunit Acry_0719 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 148260595 Common - Carbohydrate-selective porin OprB Acry_1597 15 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 148260537 Common - ATP--cobalamin adenosyltransferase Acry_1537 128 COG2096 COG2096, Uncharacterized conserved protein Function unknown 148260040 Common - acyl-CoA dehydrogenase domain protein Acry_1032 108 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148261052 Nonpathogen - hypothetical protein Acry_2060 11 COG1723 COG1723, Uncharacterized conserved protein Function unknown 148259653 Nonpathogen - hypothetical protein Acry_0640 1 None None None 148260249 Nonpathogen - hypothetical protein Acry_1246 1 None None None 148261801 Common - Pyruvate dehydrogenase (acetyl-transferring) Acry_2819 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 148259942 Common - NADH-ubiquinone oxidoreductase, chain 4L Acry_0931 92 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 148260052 Common - exporter of the RND superfamily-like protein Acry_1044 28 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 148260257 Common - aldehyde dehydrogenase Acry_1254 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148260493 Common - DNA repair protein RadC Acry_1493 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 148261555 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Acry_2572 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148261942 Common - O-antigen polymerase Acry_2960 33 None None None 148259656 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Acry_0643 139 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 148261026 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Acry_2034 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148260329 Common - phospholipase/Carboxylesterase Acry_1326 73 COG0400 COG0400, Predicted esterase General function prediction only 148259295 Common - phage integrase family protein Acry_0275 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 148260437 Common - Acetyl-CoA hydrolase Acry_1436 96 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 148261204 Common - Monosaccharide-transporting ATPase Acry_2214 83 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148259423 Common - peptide methionine sulfoxide reductase Acry_0406 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 148261221 Common - Asp/Glu racemase Acry_2233 19 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 148259251 Common rplU 50S ribosomal protein L21 Acry_0231 189 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 148261360 Nonpathogen - hypothetical protein Acry_2374 1 None None None 148259071 Common - glycine cleavage system H protein Acry_0050 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 148261282 Nonpathogen - hypothetical protein Acry_2295 1 None None None 148261693 Common - Protein-glutamate O-methyltransferase Acry_2710 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 148261600 Common - dihydroxyacetone kinase, L subunit Acry_2617 67 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 148260606 Common - protein of unknown function DUF465 Acry_1608 4 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 148259523 Common - NAD-dependent epimerase/dehydratase Acry_0507 228 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148260192 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Acry_1188 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148261428 Common - membrane protein-like protein Acry_2443 12 COG3336 COG3336, Predicted membrane protein Function unknown 148261400 Common - transcriptional regulator, LysR family Acry_2414 192 COG0583 LysR, Transcriptional regulator Transcription 148262055 Common - GPW/gp25 family protein Acry_3075 22 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 148261970 Common - short chain dehydrogenase Acry_2988 227 COG3347 COG3347, Uncharacterized conserved protein Function unknown 148259549 Common - (Uracil-5)-methyltransferase Acry_0533 87 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 148261084 Common - hypothetical protein Acry_2093 4 None None None 148261756 Common - Lysine exporter protein (LYSE/YGGA) Acry_2773 77 COG1279 COG1279, Lysine efflux permease General function prediction only 148260196 Common - GCN5-related N-acetyltransferase Acry_1192 40 COG0456 RimI, Acetyltransferases General function prediction only 148261507 Common - Baseplate J family protein Acry_2524 6 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 148259573 Common - hypothetical protein Acry_0557 15 None None None 148261842 Common - hypothetical protein Acry_2860 42 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 148261587 Nonpathogen - hypothetical protein Acry_2604 1 None None None 148262069 Nonpathogen - RNA-binding S4 domain protein Acry_3089 2 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 148259361 Common - Rhodanese domain protein Acry_0342 8 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148261041 Common - secreted (periplasmic) protein-like protein Acry_2049 4 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 148259044 Common - Heparinase II/III family protein Acry_0023 47 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 148259671 Common - Peptidoglycan glycosyltransferase Acry_0658 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148259500 Common - inner-membrane translocator Acry_0484 72 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 148260582 Common - respiratory nitrate reductase, gamma subunit Acry_1584 57 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 148259291 Common rpmF 50S ribosomal protein L32 Acry_0271 102 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 148261280 Nonpathogen - hypothetical protein Acry_2293 1 None None None 148261604 Common - DNA repair protein RadC Acry_2621 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 148261656 Nonpathogen - hypothetical protein Acry_2673 1 None None None 148261140 Common - isopropylmalate isomerase large subunit Acry_2149 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 148261616 Common rpmE 50S ribosomal protein L31 Acry_2633 167 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 148260612 Common - ICC-like protein phosphoesterase-like protein Acry_1614 44 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 148260177 Nonpathogen - hypothetical protein Acry_1173 1 None None None 148259606 Common - glycosyl transferase, group 1 Acry_0590 20 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148261720 Nonpathogen - outer membrane efflux protein Acry_2737 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148261130 Common - ribonuclease P protein component Acry_2139 12 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 148261345 Common - hypothetical protein Acry_2359 11 None None None 148261015 Common - protein of unknown function DUF583 Acry_2023 17 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 148259808 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Acry_0797 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259841 Common - short-chain dehydrogenase/reductase SDR Acry_0830 178 COG0623 FabI, Enoyl- acyl-carrier-protein 148261389 Common - parB-like partition protein Acry_2403 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 148259130 Common flgE flagellar hook protein FlgE Acry_0110 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 148259171 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Acry_0151 209 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148261500 Nonpathogen - hypothetical protein Acry_2517 1 None None None 148260371 Common - methylated-DNA--protein-cysteine methyltransferase Acry_1368 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 148260212 Common - DNA topoisomerase IV subunit A Acry_1208 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 148261542 Common - ketol-acid reductoisomerase Acry_2559 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 148260317 Common - UspA domain protein Acry_1314 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 148261014 Common - PfkB domain protein Acry_2022 87 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148261796 Common - two component transcriptional regulator, winged helix family Acry_2814 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148261412 Nonpathogen - hypothetical protein Acry_2427 1 None None None 148261485 Common - major facilitator superfamily MFS_1 Acry_2502 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261035 Common - transcriptional regulator, LysR family Acry_2043 171 COG0583 LysR, Transcriptional regulator Transcription 148260140 Common - polar amino acid ABC transporter, inner membrane subunit Acry_1136 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 148260476 Common - CMP/dCMP deaminase, zinc-binding Acry_1476 184 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 148260484 Common - NAD-dependent glycerol-3-phosphate dehydrogenase domain protein Acry_1484 206 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148260697 Common - protein of unknown function DUF6, transmembrane Acry_1701 19 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 148261154 Common - hypothetical protein Acry_2163 26 COG3346 COG3346, Uncharacterized conserved protein Function unknown 148262062 Common - protein of unknown function DUF218 Acry_3082 36 COG1434 COG1434, Uncharacterized conserved protein Function unknown 148261633 Common - D-3-phosphoglycerate dehydrogenase Acry_2650 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148261982 Common - ABC transporter related Acry_3000 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148260033 Common - alpha/beta hydrolase fold Acry_1024 101 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148259055 Common - L-carnitine dehydratase/bile acid-inducible protein F Acry_0034 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 148260958 Common - aldehyde dehydrogenase Acry_1965 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148259984 Nonpathogen - hypothetical protein Acry_0974 1 COG5305 COG5305, Predicted membrane protein Function unknown 148259583 Common - diguanylate cyclase Acry_0567 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 148260107 Common - Methyltransferase type 11 Acry_1100 23 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148260675 Common - ATP synthase F1, delta subunit Acry_1678 184 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 148260004 Common - Sarcosine oxidase, gamma subunit Acry_0995 21 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 148261686 Common - hypothetical protein Acry_2703 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 148262020 Common - hypothetical protein Acry_3039 96 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148259574 Nonpathogen - hypothetical protein Acry_0558 3 None None None 148260567 Common - cytochrome c, class I Acry_1569 4 COG3258 COG3258, Cytochrome c Energy production and conversion 148260933 Common rpsC 30S ribosomal protein S3 Acry_1940 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 148260605 Common - protein of unknown function DUF465 Acry_1607 2 None None None 148259244 Common - protein of unknown function DUF448 Acry_0224 37 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 148260919 Common - preprotein translocase, SecY subunit Acry_1926 232 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 148261308 Common - regulatory protein, LacI Acry_2322 33 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148259461 Common - Phosphotransferase system, phosphocarrier protein HPr Acry_0444 47 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 148261159 Common - Phosphatidylethanolamine N-methyltransferase Acry_2168 31 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148259186 Common - protein of unknown function DUF490 Acry_0166 82 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 148259333 Common - transcriptional regulator, MarR family Acry_0314 28 COG1846 MarR, Transcriptional regulators Transcription 148260204 Common - histone deacetylase superfamily Acry_1200 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 148259970 Common - protein of unknown function DUF395, YeeE/YedE Acry_0960 61 COG2391 COG2391, Predicted transporter component General function prediction only 148259995 Common - small multidrug resistance protein Acry_0986 96 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 148260994 Common - flavoprotein WrbA Acry_2002 116 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 148261936 Nonpathogen - protein of unknown function DUF1275 Acry_2954 1 COG3619 COG3619, Predicted membrane protein Function unknown 148259217 Common - aldehyde dehydrogenase Acry_0197 141 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 148259832 Common - Inositol phosphatase/fructose-1,6-bisphosphatase Acry_0821 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 148261315 Common - Inositol 2-dehydrogenase Acry_2329 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148259530 Common - alpha/beta hydrolase fold Acry_0514 45 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148259099 Common - pyrroloquinoline quinone biosynthesis protein PqqB Acry_0078 34 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 148261797 Common - GTP cyclohydrolase II Acry_2815 184 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 148259067 Nonpathogen - hypothetical protein Acry_0046 1 None None None 148260903 Common - phosphatidylglycerophosphatase A Acry_1910 70 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 148261565 Nonpathogen - hypothetical protein Acry_2582 1 None None None 148261196 Common - hypothetical protein Acry_2206 28 None None None 148261925 Common - hypothetical protein Acry_2943 13 None None None 148260690 Common - coproporphyrinogen III oxidase Acry_1693 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 148261065 Common - FAD dependent oxidoreductase Acry_2073 32 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148262009 Common - heavy metal translocating P-type ATPase Acry_3027 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 148259640 Common - AMP-dependent synthetase and ligase Acry_0626 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 148259149 Common - putative metalloendopeptidase, glycoprotease family Acry_0129 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 148259813 Common - hypothetical protein Acry_0802 9 None None None 148259422 Common - amidophosphoribosyltransferase Acry_0405 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 148259599 Common - riboflavin biosynthesis protein RibF Acry_0583 211 COG0196 RibF, FAD synthase Coenzyme metabolism 148261277 Common - lipoate-protein ligase B Acry_2290 168 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 148260696 Common - methionine synthase Acry_1700 176 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 148260024 Common - modification methylase, HemK family Acry_1015 191 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 148260762 Common - serine O-acetyltransferase Acry_1767 190 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 148261718 Common - acriflavin resistance protein Acry_2735 170 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 148261429 Common - surface antigen (D15) Acry_2444 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 148262000 Common - Integral membrane protein TerC Acry_3018 31 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 148261390 Common - Cobyrinic acid a,c-diamide synthase Acry_2404 209 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148259826 Nonpathogen - hypothetical protein Acry_0815 1 None None None 148261894 Common - phosphonate metabolism Acry_2912 37 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 148260126 Common - sodium/calcium exchanger membrane region Acry_1122 50 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 148259706 Nonpathogen - hypothetical protein Acry_0693 1 None None None 148259941 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Acry_0930 71 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 148261025 Common - signal transduction histidine kinase, nitrogen specific, NtrB Acry_2033 209 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 148259169 Common - hypothetical protein Acry_0149 33 COG3164 COG3164, Predicted membrane protein Function unknown 148261776 Common - glutathione-dependent formaldehyde-activating enzyme Acry_2793 16 COG3791 COG3791, Uncharacterized conserved protein Function unknown 148260085 Common - hypothetical protein Acry_1078 8 None None None 148260018 Common - 2-nitropropane dioxygenase, NPD Acry_1009 140 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 148261727 Common - polar amino acid ABC transporter, inner membrane subunit Acry_2744 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 148259499 Common - inner-membrane translocator Acry_0483 140 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148260292 Nonpathogen - hypothetical protein Acry_1289 1 None None None 148261431 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase Acry_2446 167 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 148260820 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Acry_1826 72 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 148259127 Common - Flagellar biosynthesis regulator FlbT-like protein Acry_0107 14 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 148260788 Nonpathogen - hypothetical protein Acry_1793 1 None None None 148261825 Common - hypothetical protein Acry_2843 17 None None None 148260511 Common rpsR 30S ribosomal protein S18 Acry_1511 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 148261073 Common - Lysine exporter protein (LYSE/YGGA) Acry_2082 117 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 148259033 Common - TspO and MBR like protein Acry_0012 61 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 148261205 Common - ABC transporter related Acry_2215 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259888 Nonpathogen - hypothetical protein Acry_0877 1 None None None 148259063 Common - hypothetical protein Acry_0042 19 None None None 148259286 Common - dihydroorotase Acry_0266 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 148261247 Nonpathogen - hypothetical protein Acry_2260 8 None None None 148261042 Common leuS leucyl-tRNA synthetase Acry_2050 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148260145 Common - ABC-type sugar transport system periplasmic component-like protein Acry_1141 70 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148260413 Common - hypothetical protein Acry_1411 34 COG3431 COG3431, Predicted membrane protein Function unknown 148259444 Common - protein of unknown function DUF526 Acry_0427 4 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 148261747 Common purU formyltetrahydrofolate deformylase Acry_2764 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 148261082 Common - Uncharacterized protein-like protein Acry_2091 21 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 148260318 Common - transcriptional regulator, MarR family Acry_1315 97 COG1846 MarR, Transcriptional regulators Transcription 148260219 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Acry_1216 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 148261335 Common - putative transposase Acry_2349 34 None None None 148261466 Common - natural resistance-associated macrophage protein Acry_2482 89 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 148259912 Common - NUDIX hydrolase Acry_0901 115 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 148261045 Common - thiamine monophosphate synthase Acry_2053 10 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 148259928 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Acry_0917 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148260868 Nonpathogen - cytochrome B561 Acry_1874 1 COG3038 CybB, Cytochrome B561 Energy production and conversion 148260575 Common - MaoC domain protein dehydratase Acry_1577 84 COG2030 MaoC, Acyl dehydratase Lipid metabolism 148260890 Common - type I secretion membrane fusion protein, HlyD family Acry_1897 109 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148261649 Common - BolA family protein Acry_2666 93 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 148260028 Common - integral membrane protein MviN Acry_1019 187 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 148261889 Common - hypothetical protein Acry_2907 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 148261833 Common - YCII-related protein Acry_2851 34 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 148260347 Nonpathogen - hypothetical protein Acry_1344 1 None None None 148261181 Common - spermidine synthase Acry_2191 127 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 148261577 Common - ABC transporter related Acry_2594 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148259208 Common - 1-phosphofructokinase Acry_0188 107 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 148261327 Common - DNA photolyase domain protein Acry_2341 15 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 148262015 Nonpathogen - peptidase A24A, prepilin type IV Acry_3033 1 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148261254 Common - protein of unknown function DUF59 Acry_2267 155 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 148261873 Nonpathogen - hypothetical protein Acry_2891 1 None None None 148259178 Nonpathogen - hypothetical protein Acry_0158 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 148259682 Common - molybdopterin dehydrogenase, FAD-binding Acry_0669 81 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 148259410 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Acry_0393 145 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 148260589 Common - short-chain dehydrogenase/reductase SDR Acry_1591 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261381 Common - diguanylate cyclase Acry_2395 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 148261174 Common - pyruvate phosphate dikinase Acry_2184 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 148261937 Nonpathogen - hypothetical protein Acry_2955 1 None None None 148259571 Common - pantoate--beta-alanine ligase Acry_0555 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 148260152 Common - amidohydrolase Acry_1148 155 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 148261874 Common - glutathione-dependent formaldehyde-activating, GFA Acry_2892 62 COG3791 COG3791, Uncharacterized conserved protein Function unknown 148259455 Common - chorismate mutase Acry_0438 55 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 148259479 Common - short-chain dehydrogenase/reductase SDR Acry_0463 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148260445 Common - major facilitator superfamily MFS_1 Acry_1444 96 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148261008 Common - type II secretion system protein Acry_2016 80 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 148260299 Common - single-stranded-DNA-specific exonuclease RecJ Acry_1296 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 148261136 Common - protein of unknown function DUF21 Acry_2145 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 148259544 Common - protein of unknown function DUF88 Acry_0528 62 COG1432 COG1432, Uncharacterized conserved protein Function unknown 148260229 Common rho transcription termination factor Rho Acry_1226 204 COG1158 Rho, Transcription termination factor Transcription 148261575 Common - Monosaccharide-transporting ATPase Acry_2592 121 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148260231 Common - S-adenosyl-L-homocysteine hydrolase Acry_1228 176 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 148260845 Common - catalase/peroxidase HPI Acry_1851 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 148259861 Common - branched-chain amino acid aminotransferase Acry_0850 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 148260520 Common - acyltransferase 3 Acry_1520 4 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 148260734 Common - response regulator receiver protein Acry_1738 116 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 148259090 Common - cell division protein FtsZ Acry_0069 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 148261251 Common - cystathionine beta-lyase Acry_2264 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 148261548 Common - transcriptional regulator, DeoR family Acry_2565 63 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 148259432 Common - fumarylacetoacetate (FAA) hydrolase Acry_0415 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 148259971 Common - regulatory protein, ArsR Acry_0961 119 COG0640 ArsR, Predicted transcriptional regulators Transcription 148260070 Common - periplasmic binding protein/LacI transcriptional regulator Acry_1062 90 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148262038 Common - glutamine synthetase, type I Acry_3057 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 148259120 Common - hypothetical protein Acry_0100 71 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148259625 Common - dTDP-4-dehydrorhamnose reductase Acry_0611 156 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 148260093 Common - Alpha/beta hydrolase fold-3 domain protein Acry_1086 113 COG0657 Aes, Esterase/lipase Lipid metabolism 148259807 Nonpathogen - hypothetical protein Acry_0796 4 None None None 148261968 Common - transcriptional regulator, DeoR family Acry_2986 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148261388 Common - Amidase Acry_2402 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148261625 Common - amidohydrolase 2 Acry_2642 29 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 148260416 Common hisH imidazole glycerol phosphate synthase subunit HisH Acry_1414 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 148260801 Nonpathogen - hypothetical protein Acry_1806 9 None None None 148261588 Common - periplasmic binding protein/LacI transcriptional regulator Acry_2605 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148261819 Common - glycoside hydrolase, family 17 Acry_2837 14 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 148260076 Common - type III effector Hrp-dependent outer protein Acry_1068 43 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 148260984 Common - septum site-determining protein MinD Acry_1991 148 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 148259964 Common - putative transcriptional regulator Acry_0954 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 148260386 Nonpathogen - hypothetical protein Acry_1383 1 None None None 148259112 Common - efflux transporter, RND family, MFP subunit Acry_0091 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148259384 Common - 6-phosphogluconate dehydrogenase, NAD-binding Acry_0367 151 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 148260709 Common - heat shock protein DnaJ domain protein Acry_1713 64 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 148261919 Common - glycogen debranching enzyme GlgX Acry_2937 144 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 148261164 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Acry_2174 108 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 148262074 Common - ABC transporter related Acry_3094 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148260756 Common - GTP-binding protein, HSR1-related Acry_1761 213 COG2262 HflX, GTPases General function prediction only 148261707 Common - major facilitator superfamily MFS_1 Acry_2724 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148259614 Common - methyl-accepting chemotaxis sensory transducer Acry_0599 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148259275 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Acry_0255 165 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 148260700 Nonpathogen - hypothetical protein Acry_1704 1 None None None 148259933 Common - NADH dehydrogenase subunit B Acry_0922 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 148261863 Common - pyridoxal kinase Acry_2881 55 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 148259468 Common - integral membrane sensor signal transduction histidine kinase Acry_0451 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148261541 Common - putative membrane-associated zinc metalloprotease Acry_2558 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 148259952 Common - ABC transporter related Acry_0941 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148261700 Common - beta-lactamase domain protein Acry_2717 125 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148260818 Common - MOSC domain containing protein Acry_1824 32 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 148260398 Common - hydrogenase 4 subunit B Acry_1396 195 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148260193 Common - MotA/TolQ/ExbB proton channel Acry_1189 139 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 148261451 Common - short-chain dehydrogenase/reductase SDR Acry_2467 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148261912 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like protein Acry_2930 57 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148260554 Common - acyl-CoA dehydrogenase domain protein Acry_1556 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 148259898 Common - hypothetical protein Acry_0887 3 None None None 148262027 Common - hypothetical protein Acry_3046 34 COG3258 COG3258, Cytochrome c Energy production and conversion 148259164 Common - GCN5-related N-acetyltransferase Acry_0144 139 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 148259977 Common - DSBA oxidoreductase Acry_0967 81 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 148259471 Common - protein of unknown function DUF1345 Acry_0455 41 COG4291 COG4291, Predicted membrane protein Function unknown 148259059 Common - C-terminal processing peptidase Acry_0038 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 148259517 Common - periplasmic binding protein/LacI transcriptional regulator Acry_0501 129 COG1609 PurR, Transcriptional regulators Transcription 148260960 Common - uncharacterised conserved protein UCP032025 Acry_1967 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 148261522 Common - protein of unknown function DUF6, transmembrane Acry_2539 80 None None None 148260359 Common - CBS domain containing protein Acry_1356 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 148260796 Common - Protein involved in cellulose biosynthesis (CelD)-like protein Acry_1801 10 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 148261189 Common - beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family Acry_2199 119 COG1414 IclR, Transcriptional regulator Transcription 148259851 Common - NADH dehydrogenase (quinone) Acry_0840 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148259222 Nonpathogen - hypothetical protein Acry_0202 12 None None None 148259264 Common - hypothetical protein Acry_0244 8 None None None 148259283 Common - glycosyl transferase, family 9 Acry_0263 31 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 148260100 Nonpathogen - hypothetical protein Acry_1093 1 None None None 148261128 Common - Patatin Acry_2137 50 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only