Acidiphilium cryptum JF-5 plasmid pACRY01, complete sequence NC_009467 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 148243640 Nonpathogen - hypothetical protein Acry_3109 1 None None None 148243653 Common - hypothetical protein Acry_3124 31 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 148243664 Common - glucose-methanol-choline oxidoreductase Acry_3135 83 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 148243696 Common - regulatory protein GntR, HTH Acry_3171 21 COG1802 GntR, Transcriptional regulators Transcription 148243672 Common - protein of unknown function UPF0118 Acry_3145 145 COG0628 PerM, Predicted permease General function prediction only 148243667 Nonpathogen - hypothetical protein Acry_3138 1 None None None 148243781 Common - phage integrase family protein Acry_3264 210 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148243639 Common - outer membrane efflux protein Acry_3108 4 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148243768 Common - hypothetical protein Acry_3249 18 None None None 148243686 Common - Na+/H+ antiporter NhaA Acry_3160 103 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 148243699 Common - plasmid stabilization system Acry_3174 27 COG3668 ParE, Plasmid stabilization system protein General function prediction only 148243775 Common - beta-lactamase domain protein Acry_3258 145 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148243744 Common - IstB domain protein ATP-binding protein Acry_3222 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148243718 Common - CsbD family protein Acry_3194 24 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 148243753 Nonpathogen - hypothetical protein Acry_3231 1 None None None 148243659 Nonpathogen - DoxX family protein Acry_3130 3 None None None 148243724 Common - band 7 protein Acry_3200 213 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148243713 Common - hypothetical protein Acry_3189 6 None None None 148243675 Common - transcriptional regulator, XRE family Acry_3148 19 COG1396 HipB, Predicted transcriptional regulators Transcription 148243739 Common - Methyltransferase type 11 Acry_3216 174 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148243782 Common - phage integrase family protein Acry_3265 28 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148243755 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Acry_3233 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 148243697 Common - transposase, mutator type Acry_3172 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243684 Common - Transposase-like protein Acry_3158 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 148243799 Common - Beta-lactamase class C and other penicillin binding protein-like protein Acry_3282 59 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 148243792 Common - parB-like partition protein Acry_3275 37 COG1475 Spo0J, Predicted transcriptional regulators Transcription 148243717 Common - transcriptional regulator, XRE family Acry_3193 19 COG1396 HipB, Predicted transcriptional regulators Transcription 148243658 Common - hypothetical protein Acry_3129 10 None None None 148243650 Common - hypothetical protein Acry_3121 12 None None None 148243773 Common - transcriptional regulator, Fis family Acry_3256 93 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 148243776 Common - major facilitator superfamily MFS_1 Acry_3259 28 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148243641 Common - acriflavin resistance protein Acry_3110 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 148243691 Common - IstB domain protein ATP-binding protein Acry_3166 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148243638 Common - heavy metal sensor signal transduction histidine kinase Acry_3107 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148243767 Common - Transposase and inactivated derivatives-like protein Acry_3248 38 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243804 Common - hypothetical protein Acry_3287 42 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243698 Common - Transposase and inactivated derivatives-like protein Acry_3173 45 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243747 Common - hypothetical protein Acry_3225 3 None None None 148243708 Nonpathogen - hypothetical protein Acry_3184 1 None None None 148243789 Common - WGR domain protein Acry_3272 6 COG3831 COG3831, Uncharacterized conserved protein Function unknown 148243760 Common - major facilitator superfamily MFS_1 Acry_3238 38 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 148243687 Common - transposase, IS4 family protein Acry_3161 31 COG5421 COG5421, Transposase DNA replication, recombination, and repair 148243791 Common - replication protein C Acry_3274 17 None None None 148243746 Common - hypothetical protein Acry_3224 60 COG2135 COG2135, Uncharacterized conserved protein Function unknown 148243730 Common - plasma-membrane proton-efflux P-type ATPase Acry_3206 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 148243752 Nonpathogen - hypothetical protein Acry_3230 1 None None None 148243674 Common - CsbD family protein Acry_3147 21 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 148243649 Common - hypothetical protein Acry_3119 12 None None None 148243685 Common - hypothetical protein Acry_3159 5 None None None 148243783 Common - phage integrase family protein Acry_3266 217 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148243651 Common - hypothetical protein Acry_3122 4 None None None 148243642 Common - transposase IS116/IS110/IS902 family protein Acry_3111 74 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243803 Nonpathogen - Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein Acry_3286 5 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 148243766 Common - transposase, mutator type Acry_3247 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243751 Nonpathogen - hypothetical protein Acry_3229 2 None None None 148243707 Common - hypothetical protein Acry_3183 15 None None None 148243774 Common - Rhodanese domain protein Acry_3257 72 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148243797 Nonpathogen - hypothetical protein Acry_3280 1 None None None 148243695 Common - transposase IS116/IS110/IS902 family protein Acry_3170 52 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243790 Common - helicase, RecD/TraA family Acry_3273 155 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 148243662 Common - Uncharacterized protein-like protein Acry_3133 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 148243682 Common - transposase IS116/IS110/IS902 family protein Acry_3155 69 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243648 Common - transposase IS116/IS110/IS902 family protein Acry_3118 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243742 Common - transposase, mutator type Acry_3219 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243714 Nonpathogen - hypothetical protein Acry_3190 1 None None None 148243719 Common - esterase, PHB depolymerase family Acry_3195 31 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 148243706 Common - hypothetical protein Acry_3181 25 COG4691 StbC, Plasmid stability protein General function prediction only 148243700 Nonpathogen - hypothetical protein Acry_3175 1 None None None 148243759 Common - putative transcriptional regulator, MerR family Acry_3237 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 148243677 Nonpathogen - hypothetical protein Acry_3150 1 None None None 148243745 Common - transposase, IS4 family protein Acry_3223 31 COG5421 COG5421, Transposase DNA replication, recombination, and repair 148243643 Common - hypothetical protein Acry_3112 15 None None None 148243665 Common - short-chain dehydrogenase/reductase SDR Acry_3136 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148243743 Common - Integrase, catalytic region Acry_3221 34 None None None 148243765 Common - phage integrase domain protein SAM domain protein Acry_3244 17 None None None 148243784 Common - domain of unknown function DUF1738 Acry_3267 50 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 148243676 Nonpathogen - hypothetical protein Acry_3149 1 None None None 148243694 Common - signal transduction histidine kinase with CheB and CheR activity Acry_3169 225 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 148243735 Common - transposase, mutator type Acry_3212 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243683 Common - transposase IS116/IS110/IS902 family protein Acry_3156 75 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243802 Common - uroporphyrin-III C-methyltransferase Acry_3285 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 148243733 Common - Transposase and inactivated derivatives-like protein Acry_3209 49 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243749 Nonpathogen - hypothetical protein Acry_3227 1 None None None 148243801 Common - molybdopterin oxidoreductase Acry_3284 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148243705 Common - PilT protein domain protein Acry_3180 49 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 148243796 Common - DNA binding domain, excisionase family Acry_3279 31 None None None 148243679 Nonpathogen - hypothetical protein Acry_3152 1 None None None 148243644 Common - Transposase and inactivated derivatives-like protein Acry_3113 44 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243750 Nonpathogen - hypothetical protein Acry_3228 1 None None None 148243785 Common - PilT protein domain protein Acry_3268 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 148243692 Common - Integrase, catalytic region Acry_3167 34 None None None 148243771 Common - diguanylate cyclase/phosphodiesterase Acry_3252 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 148243668 Common - glycosyltransferase 36 Acry_3139 48 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 148243725 Common - Transposase-like protein Acry_3201 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 148243710 Common - hypothetical protein Acry_3186 15 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243740 Nonpathogen - hypothetical protein Acry_3217 1 None None None 148243656 Common - hypothetical protein Acry_3127 22 None None None 148243715 Nonpathogen - hypothetical protein Acry_3191 1 None None None 148243661 Common - mercuric reductase Acry_3132 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148243720 Common - protein of unknown function UPF0118 Acry_3196 145 COG0628 PerM, Predicted permease General function prediction only 148243734 Common - hypothetical protein Acry_3211 25 None None None 148243763 Common - putative plasmid maintenance system antidote protein, XRE family Acry_3241 71 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 148243701 Nonpathogen - hypothetical protein Acry_3176 1 None None None 148243671 Common - Cyclopropane-fatty-acyl-phospholipid synthase Acry_3143 124 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148243736 Common - transposase, IS4 family protein Acry_3213 18 None None None 148243678 Common - hypothetical protein Acry_3151 9 None None None 148243680 Common - hypothetical protein Acry_3153 17 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243758 Common - E1-E2 ATPase-associated domain protein Acry_3236 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 148243795 Common - hypothetical protein Acry_3278 33 None None None 148243663 Common - glycoside hydrolase, family 39 Acry_3134 14 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 148243726 Common - transposase, IS4 family protein Acry_3202 32 COG5421 COG5421, Transposase DNA replication, recombination, and repair 148243798 Nonpathogen - hypothetical protein Acry_3281 2 None None None 148243786 Common - Rv0623 family protein transcription factor Acry_3269 6 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 148243645 Common - Transposase and inactivated derivatives-like protein Acry_3114 19 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243800 Common - Transposase and inactivated derivatives-like protein Acry_3283 44 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243660 Common - hypothetical protein Acry_3131 33 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 148243779 Common - hypothetical protein Acry_3262 8 None None None 148243772 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Acry_3253 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243741 Common - hypothetical protein Acry_3218 5 None None None 148243721 Common - response regulator receiver protein Acry_3197 20 COG4566 TtrR, Response regulator Signal transduction mechanisms 148243657 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Acry_3128 3 None None None 148243764 Common - plasmid maintenance system killer Acry_3242 42 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 148243647 Common - transposase IS116/IS110/IS902 family protein Acry_3116 70 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243702 Nonpathogen - hypothetical protein Acry_3177 2 None None None 148243794 Common - phage integrase domain protein SAM domain protein Acry_3277 52 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148243769 Common - plasmid stabilization system Acry_3250 28 COG3668 ParE, Plasmid stabilization system protein General function prediction only 148243711 Nonpathogen - hypothetical protein Acry_3187 1 None None None 148243737 Common - putative transcriptional regulator, Crp/Fnr family Acry_3214 144 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148243731 Common - transposase IS116/IS110/IS902 family protein Acry_3207 73 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243690 Common - IstB domain protein ATP-binding protein Acry_3164 93 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148243748 Common - aldehyde dehydrogenase Acry_3226 46 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 148243655 Common - transposase, mutator type Acry_3126 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243670 Common - hypothetical protein Acry_3141 26 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243722 Nonpathogen - hypothetical protein Acry_3198 1 None None None 148243770 Nonpathogen - Heme NO binding domain protein Acry_3251 1 None None None 148243688 Common - Na+/H+ antiporter NhaA Acry_3162 105 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 148243681 Common - hypothetical protein Acry_3154 11 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243654 Common - transposase, IS4 family protein Acry_3125 21 None None None 148243757 Common - Integrase, catalytic region Acry_3235 77 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243703 Nonpathogen - WGR domain protein Acry_3178 12 COG3831 COG3831, Uncharacterized conserved protein Function unknown 148243712 Common - hypothetical protein Acry_3188 28 None None None 148243637 Common - two component heavy metal response transcriptional regulator, winged helix family Acry_3106 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148243777 Nonpathogen - hypothetical protein Acry_3260 1 None None None 148243666 Nonpathogen - hypothetical protein Acry_3137 1 None None None 148243728 Nonpathogen - hypothetical protein Acry_3204 1 None None None 148243787 Common - GCN5-related N-acetyltransferase Acry_3270 44 COG0456 RimI, Acetyltransferases General function prediction only 148243727 Nonpathogen - hypothetical protein Acry_3203 1 None None None 148243780 Common - Antirestriction protein-like protein Acry_3263 18 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 148243754 Nonpathogen - hypothetical protein Acry_3232 1 None None None 148243646 Common - hypothetical protein Acry_3115 25 None None None 148243652 Common - Na+/H+ antiporter NhaA Acry_3123 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 148243732 Common - transposase, IS4 family protein Acry_3208 61 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243761 Common - beta-lactamase domain protein Acry_3239 146 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148243693 Nonpathogen - hypothetical protein Acry_3168 1 None None None 148243738 Common - Na+/H+ antiporter NhaA Acry_3215 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 148243806 Common - hypothetical protein Acry_3291 67 COG0398 COG0398, Uncharacterized conserved protein Function unknown 148243689 Common - hypothetical protein Acry_3163 4 None None None 148243729 Common - hypothetical protein Acry_3205 24 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 148243723 Nonpathogen - hypothetical protein Acry_3199 1 None None None 148243805 Nonpathogen - hypothetical protein Acry_3290 1 None None None 148243709 Common - transposase, mutator type Acry_3185 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243762 Common - regulatory protein, ArsR Acry_3240 86 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148243788 Common - Uncharacterized protein-like protein Acry_3271 11 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 148243669 Common - transposase, IS4 family protein Acry_3140 62 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 148243673 Common - esterase, PHB depolymerase family Acry_3146 31 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 148243793 Common - Cobyrinic acid a,c-diamide synthase Acry_3276 205 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148243704 Nonpathogen - hypothetical protein Acry_3179 2 None None None 148243756 Common - IstB domain protein ATP-binding protein Acry_3234 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 148243716 Nonpathogen - hypothetical protein Acry_3192 1 None None None 148243778 Common - hypothetical protein Acry_3261 15 None None None 148243636 Common - Uncharacterized membrane-associated protein-like protein Acry_3105 137 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown