Mycobacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence NC_009339 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 145226016 Common - hypothetical protein Mflv_5421 10 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 145226013 Nonpathogen - hypothetical protein Mflv_5418 5 None None None 145225940 Common - transcriptional repressor, CopY family Mflv_5343 32 COG3682 COG3682, Predicted transcriptional regulator Transcription 145225962 Common - copper resistance D domain protein Mflv_5367 27 COG3336 COG3336, Predicted membrane protein Function unknown 145226000 Common - hypothetical protein Mflv_5405 21 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 145226020 Nonpathogen - hypothetical protein Mflv_5425 1 None None None 145225981 Common - copper resistance protein CopC Mflv_5386 53 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 145225992 Common - protein of unknown function DUF955 Mflv_5397 20 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 145226138 Common - hypothetical protein Mflv_5543 12 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 145225977 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Mflv_5382 108 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 145225988 Common - hypothetical protein Mflv_5393 3 COG3462 COG3462, Predicted membrane protein Function unknown 145226118 Nonpathogen - hypothetical protein Mflv_5523 1 None None None 145226164 Nonpathogen - metallophosphoesterase Mflv_5569 13 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 145225897 Common - putative ABC transporter membrane protein Mflv_5300 4 None None None 145226143 Nonpathogen - hypothetical protein Mflv_5548 1 None None None 145226142 Common - hypothetical protein Mflv_5547 2 None None None 145226108 Common - hypothetical protein Mflv_5513 44 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 145226009 Common - transcriptional regulator, XRE family Mflv_5414 34 COG1476 COG1476, Predicted transcriptional regulators Transcription 145226087 Common - hypothetical protein Mflv_5492 3 None None None 145226031 Common - protein of unknown function DUF664 Mflv_5436 13 None None None 145225986 Common - heavy metal translocating P-type ATPase Mflv_5391 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145226037 Common - glyoxalase/bleomycin resistance protein/dioxygenase Mflv_5442 19 None None None 145226101 Common - hypothetical protein Mflv_5506 1 None None None 145226073 Common - transposase IS200-family protein Mflv_5478 74 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 145225892 Common - hypothetical protein Mflv_5294 1 None None None 145225899 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mflv_5302 1 None None None 145225907 Common - integral membrane sensor signal transduction histidine kinase Mflv_5310 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 145226094 Common - Endonuclease/exonuclease/phosphatase Mflv_5499 17 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 145225911 Common - Integrase, catalytic region Mflv_5314 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 145225923 Common - DSBA oxidoreductase Mflv_5326 73 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 145225918 Common - helix-turn-helix- domain containing protein, AraC type Mflv_5321 50 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 145225938 Common - Cytochrome-c oxidase Mflv_5341 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 145226161 Nonpathogen - hypothetical protein Mflv_5566 1 None None None 145226080 Common - FHA domain containing protein Mflv_5485 1 None None None 145226063 Common - transcriptional regulator, XRE family Mflv_5468 6 COG1396 HipB, Predicted transcriptional regulators Transcription 145226124 Nonpathogen - hypothetical protein Mflv_5529 2 None None None 145226157 Common - hypothetical protein Mflv_5562 8 None None None 145226079 Nonpathogen - hypothetical protein Mflv_5484 1 None None None 145225979 Common - cytochrome c oxidase, subunit III Mflv_5384 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 145225955 Common - transposase, mutator type Mflv_5359 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 145225874 Nonpathogen - hypothetical protein Mflv_5276 2 None None None 145226117 Nonpathogen - hypothetical protein Mflv_5522 1 None None None 145226053 Nonpathogen - hypothetical protein Mflv_5458 1 None None None 145225994 Common - phage integrase family protein Mflv_5399 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 145226047 Common - Lsr2 Mflv_5452 17 None None None 145226090 Common - transcriptional regulatory protein (probably AraC/XylS-family) Mflv_5495 38 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 145226029 Nonpathogen - hypothetical protein Mflv_5434 2 None None None 145226151 Nonpathogen - hypothetical protein Mflv_5556 1 None None None 145226075 Common - transposase, IS605 OrfB family Mflv_5480 58 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226059 Common - hypothetical protein Mflv_5464 1 None None None 145225975 Common - peptidase M48, Ste24p Mflv_5380 14 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 145225893 Nonpathogen - hypothetical protein Mflv_5296 1 None None None 145226024 Nonpathogen - hypothetical protein Mflv_5429 1 None None None 145225960 Common - hypothetical protein Mflv_5365 8 COG2367 PenP, Beta-lactamase class A Defense mechanisms 145226018 Nonpathogen - hypothetical protein Mflv_5423 2 None None None 145225942 Common - hypothetical protein Mflv_5345 13 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 145226089 Common - sulfatase Mflv_5494 68 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 145225936 Common - cytochrome c assembly protein Mflv_5339 160 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 145226055 Common - PE domain protein Mflv_5460 1 None None None 145226122 Common - ParB-like partition protein Mflv_5527 43 COG1475 Spo0J, Predicted transcriptional regulators Transcription 145226002 Common - hypothetical protein Mflv_5407 10 None None None 145226061 Nonpathogen - hypothetical protein Mflv_5466 1 COG4907 COG4907, Predicted membrane protein Function unknown 145226050 Common - transcriptional regulator, Fis family Mflv_5455 2 None None None 145226035 Common - hypothetical protein Mflv_5440 5 None None None 145225901 Common - Heavy metal transport/detoxification protein Mflv_5304 12 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 145225984 Nonpathogen - hypothetical protein Mflv_5389 1 None None None 145226166 Common - prevent-host-death family protein Mflv_5571 4 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 145226149 Nonpathogen - hypothetical protein Mflv_5554 1 None None None 145226041 Common - Integrase, catalytic region Mflv_5446 62 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226030 Common - hypothetical protein Mflv_5435 3 None None None 145226145 Nonpathogen - transcription factor WhiB Mflv_5550 2 None None None 145226082 Common - transposase, IS605 OrfB family Mflv_5487 64 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226115 Nonpathogen - hypothetical protein Mflv_5520 1 None None None 145226043 Common - transferase hexapeptide repeat containing protein Mflv_5448 192 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 145225908 Common - protein of unknown function DUF305 Mflv_5311 29 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 145226126 Common - Cobyrinic acid a,c-diamide synthase Mflv_5531 191 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 145225886 Common - NLP/P60 protein Mflv_5288 108 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145225878 Common - Methyltransferase type 11 Mflv_5280 33 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 145225996 Common - Abortive infection protein Mflv_5401 26 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 145226099 Common - filamentation induced by cAMP protein Fic Mflv_5504 100 COG3177 COG3177, Uncharacterized conserved protein Function unknown 145225944 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Mflv_5347 100 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 145225913 Nonpathogen - hypothetical protein Mflv_5316 2 None None None 145226150 Common - D12 class N6 adenine-specific DNA methyltransferase Mflv_5555 37 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 145226077 Nonpathogen - hypothetical protein Mflv_5482 1 None None None 145226092 Common - Integrase, catalytic region Mflv_5497 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226104 Common - transposase, IS4 family protein Mflv_5509 9 None None None 145226135 Common - NLP/P60 protein Mflv_5540 105 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145225959 Common - hypothetical protein Mflv_5364 10 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 145226022 Nonpathogen - hypothetical protein Mflv_5427 1 None None None 145226005 Common - hypothetical protein Mflv_5410 1 COG5654 COG5654, Uncharacterized conserved protein Function unknown 145226167 Common - PilT protein domain protein Mflv_5572 11 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 145226127 Nonpathogen - hypothetical protein Mflv_5532 1 None None None 145225927 Common - ErfK/YbiS/YcfS/YnhG family protein Mflv_5330 22 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 145225932 Nonpathogen - putative adenylate/guanylate cyclase Mflv_5335 1 None None None 145225966 Common - heavy metal translocating P-type ATPase Mflv_5371 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145225895 Common - hypothetical protein Mflv_5298 39 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 145226046 Common - transcriptional regulator, XRE family Mflv_5451 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 145225973 Common - peptidase M23B Mflv_5378 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 145225952 Common - ErfK/YbiS/YcfS/YnhG family protein Mflv_5355 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 145226017 Common - ATPase associated with various cellular activities, AAA_3 Mflv_5422 40 COG0714 COG0714, MoxR-like ATPases General function prediction only 145225945 Nonpathogen - hypothetical protein Mflv_5348 1 None None None 145225934 Common - heavy metal translocating P-type ATPase Mflv_5337 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145226086 Common - hypothetical protein Mflv_5491 5 None None None 145226130 Nonpathogen - hypothetical protein Mflv_5535 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 145226112 Nonpathogen - hypothetical protein Mflv_5517 1 None None None 145226128 Common - hypothetical protein Mflv_5533 3 None None None 145225998 Common - hypothetical protein Mflv_5403 15 None None None 145226084 Common - helix-turn-helix domain protein Mflv_5489 16 None None None 145225883 Common - hypothetical protein Mflv_5285 3 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 145225985 Common - protein of unknown function DUF302 Mflv_5390 41 COG3439 COG3439, Uncharacterized conserved protein Function unknown 145225914 Common - hypothetical protein Mflv_5317 17 None None None 145225880 Common - transposase, IS4 family protein Mflv_5282 9 None None None 145225949 Common - putative conserved lipoprotein LpqU Mflv_5352 26 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 145226051 Common - hypothetical protein Mflv_5456 59 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 145226162 Nonpathogen - hypothetical protein Mflv_5567 1 None None None 145225947 Common - NLP/P60 protein Mflv_5350 133 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145226033 Common - transposase IS3/IS911 family protein Mflv_5438 46 None None None 145226103 Nonpathogen - hypothetical protein Mflv_5508 1 None None None 145225978 Nonpathogen - hypothetical protein Mflv_5383 1 None None None 145226141 Nonpathogen - hypothetical protein Mflv_5546 1 None None None 145225957 Common - Integrase, catalytic region Mflv_5362 120 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226068 Nonpathogen - hypothetical protein Mflv_5473 1 None None None 145226137 Nonpathogen - hypothetical protein Mflv_5542 3 None None None 145226169 Common - transposase IS3/IS911 family protein Mflv_5574 79 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226007 Common - hypothetical protein Mflv_5412 1 None None None 145225983 Nonpathogen - hypothetical protein Mflv_5388 1 None None None 145225969 Common - putative adenylate/guanylate cyclase Mflv_5374 38 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 145225991 Common - hypothetical protein Mflv_5396 1 None None None 145225930 Nonpathogen - hypothetical protein Mflv_5333 1 None None None 145226071 Common - alpha/beta hydrolase fold Mflv_5476 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 145226028 Nonpathogen - protein of unknown function DUF324 Mflv_5433 2 None None None 145226011 Common - AAA ATPase Mflv_5416 8 None None None 145225971 Nonpathogen - hypothetical protein Mflv_5376 1 None None None 145225950 Common - hypothetical protein Mflv_5353 15 None None None 145225964 Common - ErfK/YbiS/YcfS/YnhG family protein Mflv_5369 21 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 145225928 Common - putative transcriptional regulator Mflv_5331 6 None None None 145226154 Common - hypothetical protein Mflv_5559 24 None None None 145225876 Nonpathogen - hypothetical protein Mflv_5278 2 None None None 145226155 Nonpathogen - hypothetical protein Mflv_5560 2 None None None 145225921 Common - NLP/P60 protein Mflv_5324 108 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145226096 Nonpathogen - hypothetical protein Mflv_5501 1 COG5373 COG5373, Predicted membrane protein Function unknown 145225993 Common - phage integrase family protein Mflv_5398 80 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 145225902 Common - heavy metal translocating P-type ATPase Mflv_5305 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145226088 Common - hypothetical protein Mflv_5493 23 COG2253 COG2253, Uncharacterized conserved protein Function unknown 145226139 Nonpathogen - hypothetical protein Mflv_5544 2 None None None 145226132 Common - cell divisionFtsK/SpoIIIE Mflv_5537 47 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 145226160 Nonpathogen - hypothetical protein Mflv_5565 1 None None None 145225881 Nonpathogen - hypothetical protein Mflv_5283 3 None None None 145225905 Nonpathogen - hypothetical protein Mflv_5308 1 None None None 145225879 Common - histidine kinase Mflv_5281 176 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 145225995 Common - Tn554 transposase C Mflv_5400 5 None None None 145226042 Common - AAA ATPase Mflv_5447 61 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 145225916 Common - regulatory protein, ArsR Mflv_5319 92 COG0640 ArsR, Predicted transcriptional regulators Transcription 145225920 Nonpathogen - putative adenylate/guanylate cyclase Mflv_5323 2 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 145225909 Common - protein of unknown function DUF302 Mflv_5312 44 COG3439 COG3439, Uncharacterized conserved protein Function unknown 145225906 Common - two component transcriptional regulator, winged helix family Mflv_5309 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 145225939 Common - peptidase M23B Mflv_5342 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 145225887 Common - response regulator receiver protein Mflv_5289 185 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 145225919 Common - hypothetical protein Mflv_5322 20 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 145226119 Common - helix-turn-helix domain protein Mflv_5524 30 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 145225954 Common - protein tyrosine phosphatase Mflv_5358 2 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 145226026 Nonpathogen - hypothetical protein Mflv_5431 2 None None None 145226110 Common - transposase, IS4 family protein Mflv_5515 27 None None None 145226158 Nonpathogen - hypothetical protein Mflv_5563 2 None None None 145226054 Common - PPE protein Mflv_5459 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 145226066 Common - hypothetical protein Mflv_5471 4 None None None 145226093 Common - diguanylate cyclase Mflv_5498 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 145225873 Nonpathogen - hypothetical protein Mflv_5275 1 None None None 145225963 Common - cytochrome c biogenesis protein, transmembrane region Mflv_5368 85 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 145225941 Common - peptidase M48, Ste24p Mflv_5344 15 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 145226048 Common - hypothetical protein Mflv_5453 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 145225980 Common - NLP/P60 protein Mflv_5385 133 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145226010 Common - hypothetical protein Mflv_5415 8 None None None 145226015 Nonpathogen - hypothetical protein Mflv_5420 2 None None None 145225956 Nonpathogen - hypothetical protein Mflv_5360 1 None None None 145225976 Common - hypothetical protein Mflv_5381 20 COG3336 COG3336, Predicted membrane protein Function unknown 145226144 Nonpathogen - transcriptional regulator, XRE family Mflv_5549 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 145226148 Nonpathogen - transcription factor WhiB Mflv_5553 1 None None None 145226038 Common - transposase IS3/IS911 family protein Mflv_5443 41 None None None 145226100 Common - hypothetical protein Mflv_5505 1 None None None 145226056 Common - cell divisionFtsK/SpoIIIE Mflv_5461 177 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 145226023 Common - phosphoadenosine phosphosulfate reductase Mflv_5428 15 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 145226064 Nonpathogen - hypothetical protein Mflv_5469 1 None None None 145226123 Common - Cobyrinic acid a,c-diamide synthase Mflv_5528 16 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 145226008 Common - hypothetical protein Mflv_5413 5 None None None 145225898 Common - hypothetical protein Mflv_5301 5 None None None 145225968 Nonpathogen - hypothetical protein Mflv_5373 3 None None None 145226032 Common - hypothetical protein Mflv_5437 52 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 145226001 Common - ErfK/YbiS/YcfS/YnhG family protein Mflv_5406 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 145225987 Common - regulatory protein, ArsR Mflv_5392 89 COG0640 ArsR, Predicted transcriptional regulators Transcription 145225885 Common - ErfK/YbiS/YcfS/YnhG family protein Mflv_5287 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 145226044 Nonpathogen - hypothetical protein Mflv_5449 1 None None None 145225877 Common - hypothetical protein Mflv_5279 4 None None None 145225900 Common - protein of unknown function DUF156 Mflv_5303 94 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 145226125 Nonpathogen - hypothetical protein Mflv_5530 2 None None None 145225910 Common - copper-translocating P-type ATPase Mflv_5313 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145226106 Nonpathogen - hypothetical protein Mflv_5511 2 None None None 145225937 Nonpathogen - hypothetical protein Mflv_5340 1 None None None 145225884 Common - hypothetical protein Mflv_5286 50 COG3000 ERG3, Sterol desaturase Lipid metabolism 145226116 Common - LtrC-like protein Mflv_5521 21 None None None 145226091 Common - transposase IS3/IS911 family protein Mflv_5496 5 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 145225943 Common - hypothetical protein Mflv_5346 19 COG3336 COG3336, Predicted membrane protein Function unknown 145225997 Common - putative conserved lipoprotein LpqU Mflv_5402 27 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 145225974 Common - transcriptional repressor, CopY family Mflv_5379 33 COG3682 COG3682, Predicted transcriptional regulator Transcription 145226098 Nonpathogen - hypothetical protein Mflv_5503 1 None None None 145225922 Common - hypothetical protein Mflv_5325 11 None None None 145226152 Nonpathogen - hypothetical protein Mflv_5557 1 None None None 145226078 Nonpathogen - hypothetical protein Mflv_5483 2 COG2944 COG2944, Predicted transcriptional regulator Transcription 145225935 Common - acyltransferase 3 Mflv_5338 71 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 145226049 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Mflv_5454 68 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 145226109 Nonpathogen - hypothetical protein Mflv_5514 3 None None None 145225933 Common - putative adenylate/guanylate cyclase Mflv_5336 15 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 145226058 Common - AAA ATPase, central domain protein Mflv_5463 87 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 145225894 Nonpathogen - hypothetical protein Mflv_5297 1 None None None 145226021 Nonpathogen - hypothetical protein Mflv_5426 2 None None None 145226121 Nonpathogen - hypothetical protein Mflv_5526 1 None None None 145226036 Common - proline iminopeptidase Mflv_5441 103 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 145225925 Common - copper resistance D domain protein Mflv_5328 28 COG3336 COG3336, Predicted membrane protein Function unknown 145226163 Nonpathogen - hypothetical protein Mflv_5568 1 None None None 145225961 Nonpathogen - hypothetical protein Mflv_5366 2 None None None 145226003 Common - hypothetical protein Mflv_5408 5 None None None 145225989 Nonpathogen - hypothetical protein Mflv_5394 2 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 145226146 Nonpathogen - hypothetical protein Mflv_5551 1 None None None 145225891 Common - response regulator receiver protein Mflv_5293 155 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 145226062 Nonpathogen - hypothetical protein Mflv_5467 1 None None None 145225872 Common - hypothetical protein Mflv_5274 3 None None None 145226114 Nonpathogen - hypothetical protein Mflv_5519 1 None None None 145226113 Nonpathogen - hypothetical protein Mflv_5518 1 None None None 145226120 Common - hypothetical protein Mflv_5525 3 None None None 145225965 Common - regulatory protein, ArsR Mflv_5370 141 COG0640 ArsR, Predicted transcriptional regulators Transcription 145226072 Common - transposase, IS605 OrfB family Mflv_5477 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226081 Nonpathogen - hypothetical protein Mflv_5486 1 None None None 145226131 Common - hypothetical protein Mflv_5536 3 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 145226057 Common - protein of unknown function DUF690 Mflv_5462 8 None None None 145226097 Common - hypothetical protein Mflv_5502 1 None None None 145226153 Common - replicative DNA helicase Mflv_5558 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 145225924 Common - protein of unknown function DUF305 Mflv_5327 36 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 145225912 Common - transposase IS3/IS911 family protein Mflv_5315 79 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 145225915 Common - heavy metal translocating P-type ATPase Mflv_5318 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145225882 Common - hypothetical protein Mflv_5284 5 None None None 145225948 Common - copper resistance protein CopC Mflv_5351 51 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 145225889 Common - transcriptional repressor, CopY family Mflv_5291 22 COG3682 COG3682, Predicted transcriptional regulator Transcription 145225903 Common - hypothetical protein Mflv_5306 10 COG3462 COG3462, Predicted membrane protein Function unknown 145226168 Nonpathogen - hypothetical protein Mflv_5573 1 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 145226004 Nonpathogen - hypothetical protein Mflv_5409 1 None None None 145226107 Common - hypothetical protein Mflv_5512 13 None None None 145226134 Common - hypothetical protein Mflv_5539 3 None None None 145225926 Common - cytochrome c biogenesis protein, transmembrane region Mflv_5329 79 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 145226067 Common - hypothetical protein Mflv_5472 5 None None None 145226052 Common - 6 kDa early secretory antigenic target EsaT6 (EsaT-6) Mflv_5457 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 145226140 Nonpathogen - hypothetical protein Mflv_5545 4 None None None 145225931 Nonpathogen - hypothetical protein Mflv_5334 3 None None None 145225999 Common - DSBA oxidoreductase Mflv_5404 70 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 145225896 Common - ABC transporter related Mflv_5299 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 145225953 Common - transposase, mutator type Mflv_5356 83 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226012 Common - Integrase, catalytic region Mflv_5417 51 None None None 145225972 Common - Cytochrome-c oxidase Mflv_5377 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 145225946 Common - cytochrome c oxidase, subunit III Mflv_5349 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 145226165 Nonpathogen - hypothetical protein Mflv_5570 1 None None None 145225967 Common - hypothetical protein Mflv_5372 3 COG3462 COG3462, Predicted membrane protein Function unknown 145226070 Nonpathogen - hypothetical protein Mflv_5475 1 None None None 145226069 Common - metal dependent phosphohydrolase Mflv_5474 6 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 145226095 Common - hypothetical protein Mflv_5500 3 None None None 145226085 Common - hypothetical protein Mflv_5490 4 None None None 145226074 Nonpathogen - hypothetical protein Mflv_5479 1 None None None 145226027 Nonpathogen - hypothetical protein Mflv_5432 2 None None None 145226133 Nonpathogen - hypothetical protein Mflv_5538 1 None None None 145226111 Common - helicase domain protein Mflv_5516 99 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 145226129 Common - NLP/P60 protein Mflv_5534 85 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145226156 Nonpathogen - hypothetical protein Mflv_5561 1 None None None 145225875 Nonpathogen - hypothetical protein Mflv_5277 1 None None None 145226076 Common - transposase IS200-family protein Mflv_5481 74 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 145225890 Common - NLP/P60 protein Mflv_5292 91 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 145226159 Nonpathogen - hypothetical protein Mflv_5564 1 None None None 145225929 Common - hypothetical protein Mflv_5332 3 COG3462 COG3462, Predicted membrane protein Function unknown 145225888 Common - hypothetical protein Mflv_5290 14 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 145225904 Common - multicopper oxidase, type 2 Mflv_5307 123 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 145225917 Common - hypothetical protein Mflv_5320 55 COG3000 ERG3, Sterol desaturase Lipid metabolism 145225951 Common - hypothetical protein Mflv_5354 23 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 145226065 Nonpathogen - hypothetical protein Mflv_5470 1 None None None 145226040 Nonpathogen - hypothetical protein Mflv_5445 2 None None None 145226039 Common - Integrase, catalytic region Mflv_5444 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226083 Nonpathogen - hypothetical protein Mflv_5488 1 None None None 145226136 Nonpathogen - hypothetical protein Mflv_5541 2 None None None 145226102 Nonpathogen - hypothetical protein Mflv_5507 1 None None None 145225982 Common - transposase, mutator type Mflv_5387 83 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226034 Common - Integrase, catalytic region Mflv_5439 118 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 145226105 Common - putative DNA methyltransferase Mflv_5510 17 COG4889 COG4889, Predicted helicase General function prediction only 145226147 Nonpathogen - hypothetical protein Mflv_5552 1 None None None 145226006 Common - putative transcriptional regulatory protein Mflv_5411 3 None None None 145225990 Nonpathogen - hypothetical protein Mflv_5395 1 None None None 145226045 Common - hypothetical protein Mflv_5450 2 None None None 145226060 Nonpathogen - hypothetical protein Mflv_5465 1 None None None 145226014 Common - hypothetical protein Mflv_5419 20 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 145226019 Nonpathogen - hypothetical protein Mflv_5424 1 None None None 145226025 Nonpathogen - hypothetical protein Mflv_5430 2 None None None 145225970 Common - heavy metal translocating P-type ATPase Mflv_5375 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 145225958 Common - transposase IS3/IS911 family protein Mflv_5363 59 None None None