Neisseria meningitidis FAM18, complete genome NC_008767 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 121634443 Common - hypothetical protein NMC0595 2 None None None 121635420 Pathogen - TspB protein NMC1715 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 121634979 Common - pseudogene (putative type III restriction-modification system modification protein) NMC1194 97 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 121634427 Common fbpA major ferric iron binding protein NMC0578 113 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 121634235 Common - hypothetical protein NMC0369 17 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121635542 Common rpmB 50S ribosomal protein L28 NMC1851 170 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 121635001 Common - hypothetical protein NMC1221 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 121635108 Common - lipid A biosynthesis lauroyl acyltransferase NMC1351 107 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 121635228 Common - hypothetical protein NMC1491 118 COG0795 COG0795, Predicted permeases General function prediction only 121634900 Common glnD putative [protein-PII] uridylyltransferase NMC1104 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 121634538 Common recN putative DNA repair protein NMC0694 205 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 121635351 Common mtrD probable drug efflux protein NMC1633 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121635236 Common hisG ATP phosphoribosyltransferase catalytic subunit NMC1499 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 121634211 Pathogen - hypothetical protein NMC0344 1 None None None 121634750 Common sdhC putative succinate dehydrogenase cytochrome B subunit NMC0925 74 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 121635610 Common - CaDmium resistance protein NMC1927 19 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 121635256 Common - potassium-tellurite ethidium and proflavin transporter NMC1523 33 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 121635617 Pathogen - hypothetical protein NMC1934 1 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 121634309 Pathogen - conservative hypothetical protein NMC0449 1 None None None 121634778 Common pntB pyridine nucleotide transhydrogenase NMC0958 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 121633971 Pathogen - putative inner membrane protein NMC0083 1 None None None 121635006 Pathogen - hypothetical protein NMC1229 1 None None None 121634564 Common pilT2 putative pilus retraction protein NMC0721 217 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 121635344 Common - hypothetical periplasmic protein NMC1623 39 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 121635191 Common - hypothetical protein NMC1449 23 None None None 121635244 Common - putative integral membrane protein NMC1507 8 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 121633969 Pathogen - hypothetical protein NMC0080 1 None None None 121634529 Common bioA putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase NMC0685 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 121635497 Pathogen - hypothetical protein NMC1801 1 None None None 121635272 Common - hypothetical protein NMC1546 82 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 121634469 Common - putative periplasmic protein NMC0622 4 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 121635273 Common gpxA glutathione peroxidase NMC1547 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 121635203 Common - hypothetical protein NMC1461 17 None None None 121635063 Common - hypothetical membrane protein NMC1292 20 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 121635680 Common - hypothetical protein NMC2002 194 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 121634170 Common - putative transposase for IS1106A3 NMC0299 41 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634471 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase NMC0624 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 121634938 Pathogen - putative periplasmic protein NMC1146 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 121634766 Common - putative outer-membrane receptor protein NMC0944 68 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121635166 Common - putative fimbrial assembly protein NMC1422 9 None None None 121635574 Common - putative TonB-dependent receptor protein NMC1887 110 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 121635637 Common cyaY frataxin-like protein NMC1954 43 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 121634299 Pathogen - putative lipoprotein NMC0437 1 None None None 121635245 Common - predicted inner membrane peptidase NMC1508 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121633962 Common - hypothetical protein NMC0068 69 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 121634496 Common - hypothetical protein NMC0649 10 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 121634806 Common - hypothetical protein NMC0993 8 None None None 121635642 Common iga2 IgA-specific serine endopeptidase NMC1959 9 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121633976 Common - putative IS1106 transposase NMC0088 42 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634709 Common - putative plamid toxin PemK protein NMC0879 39 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 121634567 Common - hypothetical protein NMC0724 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 121634053 Common - hypothetical protein NMC0169 9 None None None 121634398 Common - putative zinc-binding alcohol dehydrogenase NMC0547 172 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 121634680 Common - hypothetical protein NMC0846 4 COG5532 COG5532, Uncharacterized conserved protein Function unknown 121634016 Common rplC 50S ribosomal protein L3 NMC0132 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 121635386 Common - hypothetical protein NMC1675 14 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 121634837 Common - putative cell-division protein NMC1031 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 121635692 Common - D,D-heptose 1,7-bisphosphate phosphatase NMC2014 128 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 121635773 Common - putative protease NMC2103 158 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121634499 Common comA competence protein NMC0652 157 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 121635554 Pathogen - putative integral membrane protein NMC1865 1 None None None 121634066 Common - hypothetical protein NMC0182 206 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 121635105 Pathogen - putative rtx iron-regulated frpc protein outer membrane NMC1344 1 None None None 121635526 Common - putative inner membrane hypothetical protein NMC1832 2 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 121634554 Common pnp polynucleotide phosphorylase/polyadenylase NMC0710 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 121634414 Common - hypothetical protein NMC0565 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 121634206 Common - hypothetical protein NMC0339 34 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 121635755 Common rpsB 30S ribosomal protein S2 NMC2080 220 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 121634506 Pathogen - hypothetical protein NMC0659 1 None None None 121635522 Common - putative morphogene NMC1828 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 121635529 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase NMC1835 137 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 121635794 Common purD phosphoribosylamine--glycine ligase NMC2129 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 121635759 Pathogen mafB adhesin NMC2084 1 None None None 121635264 Pathogen - hypothetical protein NMC1532 1 None None None 121634224 Common accC putative acetyl-CoA carboxylase biotin carboxylase component NMC0357 234 COG0439 AccC, Biotin carboxylase Lipid metabolism 121634227 Common - hypothetical protein NMC0361 47 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 121634099 Common - hypothetical protein NMC0223 2 None None None 121634002 Common - elongation factor Tu NMC0116 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 121634104 Common - hypothetical protein NMC0228 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 121634320 Common - hypothetical protein NMC0464 175 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 121635515 Common - glutamyl-Q tRNA(Asp) synthetase NMC1820 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 121635312 Common - hypothetical integral membrane protein NMC1589 68 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 121633903 Pathogen pilS2 truncated pilin NMC0003 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 121635673 Pathogen - putative pilin NMC1995 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121633928 Pathogen - hypothetical protein NMC0029 1 None None None 121635625 Common aldA aldehyde dehydrogenase A NMC1942 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121634246 Common - putative lipopolysaccharide modification acyltransferase NMC0380 106 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 121634487 Common greB transcription elongation factor GreB NMC0640 180 COG0782 GreA, Transcription elongation factor Transcription 121635187 Common - putative inner membrane protein NMC1445 26 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 121635605 Common rpsU 30S ribosomal protein S21 NMC1921 97 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 121634008 Common rplL 50S ribosomal protein L7/L12 NMC0122 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 121633948 Pathogen - alpha-2,9-polysialyltransferase NMC0051 2 None None None 121634540 Common - hypothetical protein NMC0696 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 121635768 Pathogen - hypothetical protein NMC2095 1 None None None 121634861 Pathogen - putative phage tail fibre protein NMC1058 3 None None None 121633926 Pathogen - putative inner membrane protein NMC0027 1 None None None 121635069 Common xseA exodeoxyribonuclease VII large subunit NMC1298 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 161723300 Common accD acetyl-CoA carboxylase subunit beta NMC0629 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 121634389 Common - putative two-component system sensor kinase NMC0536 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121634184 Common - hypothetical protein NMC0315 205 COG0313 COG0313, Predicted methyltransferases General function prediction only 121635505 Common glnA glutamine synthetase NMC1809 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 121635812 Common - hypothetical protein NMC2147 60 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 121634909 Common - hypothetical protein NMC1115 7 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121634069 Common - putative inner membrane amino-acid transport protein NMC0185 115 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 121634697 Common - hypothetical protein NMC0864 8 None None None 121634549 Common xerD putative integrase/recombinase NMC0705 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 121634792 Common - hypothetical protein NMC0973 18 COG3422 COG3422, Uncharacterized conserved protein Function unknown 121635368 Common grxB glutaredoxin 2 NMC1654 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 121635410 Common recO DNA repair protein (recombination protein o) NMC1704 68 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 121633990 Common - SUN-family protein NMC0104 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 121635015 Common - putative transcriptional regulator NMC1240 78 COG0789 SoxR, Predicted transcriptional regulators Transcription 121634601 Common - hypothetical protein NMC0760 48 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121635164 Common surE SurE protein NMC1419 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 121635131 Common dnaZX DNA polymerase III subunits gamma and tau NMC1379 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 121635741 Common obgE GTPase ObgE NMC2065 232 COG0536 Obg, Predicted GTPase General function prediction only 121634996 Common mfd transcription-repair coupling factor NMC1214 228 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 121634731 Common pip putative proline iminopeptidase NMC0905 112 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121635644 Pathogen - hypothetical protein NMC1961 1 None None None 121634464 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase NMC0617 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 121635581 Common - hypothetical protein NMC1898 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 121634763 Common - putative ATP-dependent helicase NMC0940 12 COG3972 COG3972, Superfamily I DNA and RNA helicases General function prediction only 121635458 Common - putative integral membrane antobiotic resistance protein NMC1759 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 121634597 Common - putative NAD(P)H-flavin oxidoreductase NMC0756 91 COG0778 NfnB, Nitroreductase Energy production and conversion 121634981 Common - hypothetical protein NMC1196 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 121634650 Common prsA ribose-phosphate pyrophosphokinase NMC0816 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 121635422 Common - hypothetical protein NMC1717 9 COG4128 Zot, Zonula occludens toxin General function prediction only 121634276 Common pilN putative pilus assembly protein NMC0411 38 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 121635265 Common hisJ histidine-binding periplasmic protein NMC1533 184 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121634647 Common - putative periplasmic protein NMC0813 105 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 121635067 Common - putative pseudouridine synthase NMC1296 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121634581 Common - putative amino acid permease substrate-binding protein NMC0739 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121634045 Common minD septum site-determining protein NMC0161 145 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 121634466 Common tdk thymidylate kinase NMC0619 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 121635595 Common atpE ATP synthase C chain NMC1911 55 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 121634457 Common - putative transmembrane potassium transporter NMC0609 145 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 121634729 Common opaD pseudogene (opacity protein) NMC0903 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121635088 Common hscB chaperone protein NMC1319 57 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 121634810 Pathogen - hypothetical protein NMC0999 1 None None None 121635144 Common fumC fumarate hydratase NMC1396 210 COG0114 FumC, Fumarase Energy production and conversion 121635659 Common - hypothetical protein NMC1979 8 None None None 121635194 Pathogen - putative proline-rich repeat protein NMC1452 1 None None None 121634023 Common rplP 50S ribosomal protein L16 NMC0139 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 121635085 Common - NifS-like aminotranfserase NMC1315 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 121633998 Pathogen - putative inner membrane protein NMC0112 1 None None None 121634624 Common - putative periplasmic protein NMC0788 20 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 121634815 Common - putative transposase NMC1006 109 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634954 Common - putative lipoprotein NMC1164 2 None None None 121634181 Common rpmF 50S ribosomal protein L32 NMC0312 110 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 121635156 Common - aminotransferase AlaT NMC1410 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121635375 Pathogen - hypothetical protein NMC1663 1 None None None 121635805 Pathogen - putative periplasmic protein NMC2140 1 None None None 121634377 Common - putative peptidase NMC0524 42 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 121635151 Common - hypothetical protein NMC1404 12 None None None 121635720 Common thiF ThiF protein NMC2043 216 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 121634877 Common - hypothetical protein NMC1077 83 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 121634134 Common - putative ABC transporter NMC0258 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 121635325 Common serS seryl-tRNA synthetase NMC1602 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635081 Common - putative type III restriction/modification system modification methylase NMC1310 113 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 121635072 Common trxA thioredoxin I NMC1301 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 121635814 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase NMC2149 224 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 121635076 Pathogen - hypothetical protein NMC1305 1 None None None 121635437 Common prpB 2-methylisocitrate lyase NMC1733 135 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 121634341 Common adhA alcohol dehydrogenase NMC0486 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 121634268 Common ribD putative diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase NMC0403 231 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 121635275 Common aniA nitrite reductase, major outer membrane copper-containing protein NMC1549 72 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 121634588 Common pth peptidyl-tRNA hydrolase NMC0747 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 121635450 Common murF UDP-MurNAc-pentapeptide synthetase NMC1749 203 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 121635173 Common rph ribonuclease PH NMC1430 180 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 121634842 Common lgt prolipoprotein diacylglyceryl transferase NMC1036 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 121634912 Common - putative transcriptional regulator NMC1118 147 COG1846 MarR, Transcriptional regulators Transcription 121634402 Common secF preprotein translocase subunit SecF NMC0551 214 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 121634895 Common - hypothetical protein NMC1097 45 COG3658 COG3658, Cytochrome b Energy production and conversion 121635729 Common thiG thiazole synthase NMC2052 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 121634446 Pathogen - hypothetical protein NMC0598 3 None None None 121634537 Common - hypothetical protein NMC0693 137 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 121634968 Pathogen - type II restriction endonuclease (pseudogene) NMC1181 1 None None None 121634888 Common ilvD dihydroxy-acid dehydratase NMC1090 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 121635242 Common - putative transcriptional regulator NMC1505 13 COG1846 MarR, Transcriptional regulators Transcription 121635495 Pathogen - hypothetical protein NMC1799 1 None None None 121635418 Pathogen - putative integral membrane protein NMC1713 1 None None None 121635205 Common secA preprotein translocase subunit SecA NMC1464 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 121635699 Common thiC thiamine biosynthesis protein ThiC NMC2021 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 121634012 Common rpsG 30S ribosomal protein S7 NMC0126 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 121634641 Common - putative periplasmic protein NMC0807 4 None None None 121635336 Common - putative integral membrane protein NMC1614 27 COG4648 COG4648, Predicted membrane protein Function unknown 121634049 Common - zinc transporter ZupT NMC0165 99 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 121635014 Common hip integration host factor beta-subunit NMC1239 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 121634171 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase NMC0302 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121634655 Common cysW putative sulphate permease inner membrane protein NMC0821 209 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 121635744 Common - hypothetical protein NMC2069 150 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 121635747 Pathogen - putative periplasmic protein NMC2072 1 None None None 121635053 Common - putative TonB-dependent receptor protein NMC1282 67 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121633955 Common ctrD capsule polysaccharide export ATP-binding protein CtrD NMC0058 248 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 121634960 Common - putative periplasmic protein NMC1172 6 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 121634140 Common - putative hydrolase NMC0264 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121634477 Common cnp1 putative periplasmic protein NMC0630 3 None None None 121635556 Pathogen - Putative integral membrane protein NMC1867 1 None None None 121635379 Pathogen - putative cell-surface protein NMC1668 1 None None None 121634532 Common ubiA 4-hydroxybenzoate octaprenyltransferase NMC0688 167 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 121635667 Common - putative DNA helicase NMC1987 86 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 121634374 Common - putative ABC-transporter ATP-binding protein NMC0521 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 121634553 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase NMC0709 176 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 121635049 Common aceE pyruvate dehydrogenase subunit E1 NMC1278 147 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 121634281 Common - hypothetical protein NMC0417 62 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 121634147 Common - putative thiol:disulphide interchange protein NMC0273 40 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121634153 Pathogen - hypothetical protein NMC0279 1 None None None 121634998 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase NMC1218 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 121635449 Pathogen - putative periplasmic protein NMC1748 1 None None None 121634543 Common folK putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine- pyrophosphokinase NMC0699 194 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 121634336 Pathogen - hypothetical protein NMC0480 2 None None None 121634720 Pathogen - hypothetical protein NMC0892 1 None None None 121635279 Common - hypothetical protein NMC1553 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 121634126 Pathogen - hypothetical protein NMC0250 1 None None None 121634948 Common ribB bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein NMC1157 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 121634482 Common ribH riboflavin synthase subunit beta NMC0635 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 121634087 Common - hypothetical protein NMC0209 35 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635700 Common - hypothetical protein NMC2022 19 None None None 121635118 Common porA porin, class I outer membrane protein NMC1364 30 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 161723296 Common rpmE 50S ribosomal protein L31 NMC1928 204 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 121634330 Common - putative transmembrane hexose transporter NMC0474 56 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 121634921 Common hom homoserine dehydrogenase NMC1128 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 121635291 Common alr alanine racemase NMC1567 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 121634883 Pathogen - putative periplasmic protein NMC1084 1 None None None 121635185 Common dnaQ DNA polymerase III, epsilon chain NMC1443 182 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 121634633 Pathogen - hypothetical protein NMC0798 1 None None None 121634977 Common - hypothetical protein NMC1192 164 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 121635286 Common - putative haemolysin NMC1560 112 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 121633985 Common pyrI aspartate carbamoyltransferase regulatory subunit NMC0099 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 121634050 Common dadA D-amino acid dehydrogenase small subunit NMC0166 139 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121634959 Common - hypothetical protein NMC1171 211 COG2262 HflX, GTPases General function prediction only 121634694 Pathogen - hypothetical protein NMC0861 1 None None None 121634704 Pathogen - hypothetical protein NMC0871 1 None None None 121635215 Common dgk diacylglycerol kinase NMC1475 68 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 121633905 Common - hypothetical protein NMC0005 24 COG3205 COG3205, Predicted membrane protein Function unknown 121634256 Common - hypothetical protein NMC0390 48 COG2501 COG2501, Uncharacterized conserved protein Function unknown 121635098 Common eda keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase NMC1333 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 121634776 Pathogen - putative cell-surface protein NMC0956 1 None None None 121635481 Common - transcriptional regulator CysB-like protein NMC1784 189 COG0583 LysR, Transcriptional regulator Transcription 121634520 Common rplT 50S ribosomal protein L20 NMC0675 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 121634353 Pathogen - hypothetical protein NMC0499 1 None None None 121635619 Common - putative outer membrane transport protein NMC1936 100 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 121635193 Common - putative peptidyl-prolyl isomerase NMC1451 126 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 121634055 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NMC0171 151 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 121634175 Common - putative integral membrane protein NMC0306 55 COG3326 COG3326, Predicted membrane protein Function unknown 121634248 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase NMC0382 211 COG0196 RibF, FAD synthase Coenzyme metabolism 121634808 Common - putative phage repressor NMC0997 8 COG1476 COG1476, Predicted transcriptional regulators Transcription 121634302 Pathogen - hypothetical protein NMC0440 1 None None None 121633946 Common galE UDP-glucose 4-epimerase NMC0048 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 121635357 Common - putative integral membrane protein NMC1639 67 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 121634517 Common thrS putative threonyl-tRNA synthetase NMC0672 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121634186 Common - hypothetical protein NMC0317 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 121634675 Pathogen - putative D-lactate dehydrogenase-related protein NMC0841 1 None None None 121635136 Common rep ATP-dependent DNA helicase NMC1385 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121634914 Pathogen - hypothetical protein NMC1121 1 None None None 121633960 Common lipA capsule polysaccharide modification protein NMC0066 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 121634768 Common trpD putative anthranilate phosphoribosyltransferase NMC0948 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 121634090 Common - RNA polymerase sigma factor NMC0212 104 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 121635544 Common emrA multidrug resistance translocase NMC1853 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121634478 Common - hypothetical protein NMC0631 115 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121635388 Common - hypothetical protein NMC1677 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 121634936 Common ruvB Holliday junction DNA helicase B NMC1144 233 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 121635229 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase NMC1492 217 COG1049 AcnB, Aconitase B Energy production and conversion 121635477 Common - putative ABC transporter ATP-binding protein NMC1780 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121634732 Common - putative lipoprotein NMC0906 26 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 121635697 Common chpA PEMK-like protein NMC2019 54 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 121635510 Common - putative periplasmic hypothetical protein NMC1814 16 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 121634957 Common fpr putative ferredoxin--NADP reductase NMC1168 111 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 121634714 Common - Putative transposase for IS1106A3 NMC0884 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634448 Pathogen - hypothetical protein NMC0600 2 None None None 121634291 Common - putative two-component system sensor kinase NMC0429 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121635639 Common - S-ribosylhomocysteinase NMC1956 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 121635630 Common hpuB haemoglobin-haptoglobin-utilization protein NMC1947 49 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121635672 Common - hypothetical protein NMC1994 16 None None None 121635416 Pathogen - hypothetical protein NMC1711 1 None None None 121634162 Common - hypothetical protein NMC0289 151 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 121635222 Common - hypothetical protein NMC1485 6 None None None 121634064 Pathogen - putative inner membrane protein NMC0180 1 None None None 121635690 Common - putative integral membrane protein NMC2012 28 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 121634562 Common lepA GTP-binding protein LepA NMC0719 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 121633958 Common rfbA2 glucose-1-phosphate thymidylyltransferase NMC0064 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 121634300 Pathogen - hypothetical protein NMC0438 1 None None None 121635612 Common - putative acetyltransferase NMC1929 36 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 121634214 Common - putative acetyltransferase NMC0347 154 COG0456 RimI, Acetyltransferases General function prediction only 121635366 Common - putative integral membrane protein NMC1652 99 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 121635003 Common nrdB ribonucleotide-diphosphate reductase subunit beta NMC1223 151 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 121635161 Common recX recombination regulator RecX NMC1415 52 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 121635350 Common mtrE putative outer membrane lipoprotein NMC1632 125 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121635008 Common fpg formamidopyrimidine-DNA glycosylase NMC1232 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 121633981 Common - hypothetical protein NMC0095 2 None None None 121634460 Common nspA outer membrane protein NMC0612 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121635062 Common gatA Glu-tRNA(Gln) amidotransferase subunit A NMC1291 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 121635677 Common - putative integral membrane protein NMC1999 79 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 121634213 Common - hypothetical protein NMC0346 34 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 121635234 Common ilvI acetolactate synthase isozyme III large subunit NMC1497 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 121635254 Common - hypothetical protein NMC1519 6 None None None 121635429 Common - hypothetical protein NMC1725 146 COG1959 COG1959, Predicted transcriptional regulator Transcription 121634030 Common rpsH 30S ribosomal protein S8 NMC0146 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 121634784 Common - putative transposase NMC0964 52 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634264 Common - Pglb2 NMC0399 182 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 121635147 Common - putative integral membrane transporter NMC1400 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121634685 Pathogen - hypothetical protein NMC0852 1 None None None 121635681 Common - hypothetical protein NMC2003 187 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 121635705 Common hpt hypoxanthine-guanine phosphoribosyltransferase NMC2027 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 121635046 Common - Holliday junction resolvase-like protein NMC1275 182 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 121635372 Common - hypothetical protein NMC1660 2 None None None 121634571 Pathogen - putative secreted protein NMC0729 2 None None None 121634387 Common rpsP 30S ribosomal protein S16 NMC0534 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 121635766 Pathogen - hypothetical protein NMC2092 1 None None None 121635470 Common nadA quinolinate synthetase NMC1772 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 121633931 Common pilC pilus assembly protein PilC NMC0033 31 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 161723301 Common trpA tryptophan synthase subunit alpha NMC0628 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 121635247 Pathogen - hypothetical protein NMC1511 1 None None None 121635314 Common tag DNA-3-methyladenine glycosylase I NMC1591 131 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 121635513 Common tal transaldolase NMC1818 97 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 121634740 Common efp elongation factor P NMC0915 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 121635623 Common - hypothetical protein NMC1940 6 None None None 121635503 Common - hypothetical protein NMC1807 62 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 121634121 Common nuoH NADH dehydrogenase I chain H NMC0245 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 121634707 Common - putative ATP binding protein NMC0877 14 None None None 121635282 Common nusA transcription elongation factor NusA NMC1556 218 COG0195 NusA, Transcription elongation factor Transcription 121635120 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase NMC1366 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 121634695 Common - hypothetical protein NMC0862 8 None None None 121635122 Common - phopholipase D-family protein NMC1368 148 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 121634794 Common - putative transposase for IS1655 NMC0976 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121634018 Common rplW 50S ribosomal protein L23 NMC0134 111 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 121635389 Common - putative integral membrane transport protein NMC1679 87 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 121634250 Common lspA lipoprotein signal peptidase NMC0384 194 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121634208 Common - putative araC-family transcriptional regulator NMC0341 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121635103 Common - putative cytolysin secretion ABC transporter NMC1342 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 121634620 Common recJ putative single-stranded-DNA-specific exonuclease NMC0780 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 121634835 Common - putative integral membrane protein NMC1029 22 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 121634409 Common - putative IS1106 transposase (pseudogene) NMC0558 17 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121635039 Common trmB tRNA (guanine-N(7))-methyltransferase NMC1267 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 121634858 Common gam putative host-nuclease inhibitor protein NMC1054 7 COG4396 COG4396, Mu-like prophage host-nuclease inhibitor protein Gam General function prediction only 121634240 Common - putative marR-family transcriptional regulator NMC0374 37 COG1846 MarR, Transcriptional regulators Transcription 121634158 Pathogen - putative inner membrane protein NMC0284 1 None None None 121634556 Pathogen - putative lipoprotein NMC0712 1 None None None 121635757 Common pyrH uridylate kinase NMC2082 236 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 121633921 Common pilA probable signal recognition particle protein NMC0021 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 121634380 Common frpC iron-regulated protein FrpC NMC0527 103 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 121635092 Common pgi glucose-6-phosphate isomerase NMC1326 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 121634643 Common - hypothetical protein NMC0809 76 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 121634508 Common - hypothetical protein NMC0661 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 121635404 Common - putative secreted protein NMC1698 4 None None None 121634774 Pathogen - putative integral membrane protein NMC0954 1 None None None 121634072 Common rluC ribosomal large subunit pseudouridine synthase C NMC0190 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121634200 Pathogen secG preprotein translocase subunit SecG NMC0333 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 121634097 Pathogen - hypothetical protein NMC0221 1 None None None 121635342 Pathogen - hypothetical protein NMC1621 1 None None None 121634106 Common uvrD DNA helicase II NMC0230 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121635407 Common - hypothetical protein NMC1701 4 COG0730 COG0730, Predicted permeases General function prediction only 121635796 Common - hypothetical protein NMC2131 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 121633993 Common - putative two-component trancriptional regulator NMC0107 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121634229 Common carB carbamoyl phosphate synthase large subunit NMC0363 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 121635753 Common - hypothetical protein NMC2078 156 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 121635565 Pathogen - hypothetical protein NMC1876 1 None None None 121635394 Common - putative integral membrane protein NMC1686 77 COG2928 COG2928, Uncharacterized conserved protein Function unknown 121635801 Common - hypothetical protein NMC2136 94 COG1720 COG1720, Uncharacterized conserved protein Function unknown 121633967 Common pykA pyruvate kinase NMC0074 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 121635323 Common parE DNA topoisomerase IV subunit B NMC1600 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 121634875 Pathogen - hypothetical protein NMC1074 1 None None None 121635078 Common clpX ATP-dependent protease ATP-binding subunit NMC1307 240 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 121635722 Common - putative integral membrane protein NMC2045 29 COG2056 COG2056, Predicted permease General function prediction only 121634025 Common rpsQ 30S ribosomal protein S17 NMC0141 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 121635115 Common lysS lysyl-tRNA synthetase NMC1361 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 121634974 Common - hypothetical protein NMC1189 110 COG2606 EbsC, Uncharacterized conserved protein Function unknown 121635042 Common - putative carboxy-terminal processing protease NMC1270 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 121635567 Pathogen - hypothetical protein NMC1879 1 None None None 121635816 Common - putative integral membrane protein NMC2151 6 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 121633983 Common - hypothetical protein NMC0097 32 COG0456 RimI, Acetyltransferases General function prediction only 121635571 Common - putative transposase for IS1655 NMC1884 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121634897 Common typA putative GTP-binding protein NMC1099 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 121634136 Common - hypothetical protein NMC0260 5 COG3212 COG3212, Predicted membrane protein Function unknown 121635100 Common sodC superoxide dismutase NMC1339 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 121634753 Common sdhB succinate dehydrogenase iron-sulfur subunit NMC0928 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 121635439 Common ftsZ cell division protein FtsZ NMC1737 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 121634343 Common - putative periplasmic protein NMC0488 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121635079 Common rbfA ribosome-binding factor A NMC1308 167 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 121634622 Pathogen - putative periplasmic protein NMC0782 1 None None None 121635074 Common - putative ATP-dependent RNA helicase NMC1303 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121634313 Pathogen - hypothetical protein NMC0453 5 None None None 121634273 Common pilQ pilus secretin NMC0408 138 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 121634385 Common trmD putative tRNA (guanine-N1)-methyltransferase NMC0532 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 121635484 Common - putative phosphate permease NMC1787 171 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 121635171 Common - putative outer membrane substrate binding protein NMC1428 26 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121635461 Common - putative chelatase NMC1763 191 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 121634266 Common - pseudogene (putative glycosyl transferase) NMC0401 164 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121634371 Common hemA glutamyl-tRNA reductase NMC0518 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 121634400 Common - hypothetical protein NMC0549 164 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 121635440 Common ftsA cell division protein NMC1738 184 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 121635664 Common - ATP-dependent DNA helicase NMC1984 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 121635316 Pathogen - putative integral membrane protein NMC1593 1 None None None 121635196 Common - putative virulence associated protein NMC1454 14 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121635657 Common hslO Hsp33-like chaperonin NMC1977 127 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 121635456 Common - hypothetical protein NMC1756 133 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 121634847 Common - ABC-transporter ATP-binding protein (pseudogene) NMC1041 207 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 121634595 Common - putative carbon-sulphur lyase NMC0754 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 121635050 Common aceF dihydrolipoamide acetyltransferase NMC1279 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 121634459 Common - hypothetical protein NMC0611 193 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 121634765 Common - phosphatidylserine decarboxylase NMC0942 93 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 121634987 Common - putative mercuric ion binding protein NMC1202 105 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 121634450 Pathogen - hypothetical protein NMC0602 2 None None None 121635374 Common - hypothetical protein NMC1662 5 None None None 121634233 Pathogen - hypothetical protein NMC0367 1 None None None 121634727 Common - putative oxidoreductase NMC0901 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121634817 Common - transposase for IS1655 NMC1008 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121635798 Common etfB electron transfer flavoprotein beta-subunit NMC2133 149 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 121634747 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase NMC0922 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 121633953 Common ctrB capsule polysaccharide export inner-membrane protein NMC0056 39 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 121634849 Common - putative DNA-binding protein NMC1044 3 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 121634076 Common dapB dihydrodipicolinate reductase NMC0195 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 121634615 Common - putative ATP-dependent Clp protease adaptor protein clpS NMC0775 117 COG2127 COG2127, Uncharacterized conserved protein Function unknown 121634631 Common - putative periplasmic protein NMC0795 41 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 121635621 Common - putative ABC transport ATP-binding protein NMC1938 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 121634829 Common - hypothetical protein NMC1021 21 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 121634629 Common - hypothetical protein NMC0793 45 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 121634885 Common bioB putative biotin synthase NMC1087 177 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 121635178 Common argS arginyl-tRNA synthetase NMC1436 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635628 Common - hypothetical periplasmic protein NMC1945 12 None None None 121635027 Pathogen - hypothetical protein NMC1253 1 None None None 121634661 Pathogen - hypothetical protein NMC0827 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 121634907 Common - putative integral membrane protein NMC1113 128 COG0628 PerM, Predicted permease General function prediction only 121635301 Common rpoZ DNA-directed RNA polymerase omega chain NMC1578 111 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 121634293 Common - putative glutaredoxin NMC0431 117 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 121634259 Common - hypothetical protein NMC0394 121 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 121635803 Common mutS DNA mismatch repair protein NMC2138 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 121634868 Common - short chain dehydrogenase NMC1067 185 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121634952 Common - putative lysR-family transcriptional regulator NMC1162 186 COG0583 LysR, Transcriptional regulator Transcription 121635395 Common rpsT 30S ribosomal protein S20 NMC1688 206 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 121634071 Common rne ribonuclease E NMC0187 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 121635738 Common - putative nuclease NMC2061 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 121634822 Common trpE putative anthranilate synthase component I NMC1013 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 121635561 Common - hypothetical protein NMC1872 47 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 121635288 Common - hypothetical protein NMC1563 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 121634692 Pathogen - hypothetical protein NMC0859 1 None None None 121634923 Common hupB putative DNA-binding protein NMC1130 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 121633923 Common - conserved hypothetical protein (putative ATP-binding protein) NMC0023 9 COG4128 Zot, Zonula occludens toxin General function prediction only 121634434 Common ntpA dATP pyrophosphohydrolase NMC0585 55 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121634757 Common sucB dihydrolipoamide acetyltransferase NMC0932 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 121635149 Common - hypothetical protein NMC1402 41 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635213 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase NMC1473 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 121634149 Common - putative outer membrane solvent tolerance protein NMC0275 115 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 121635277 Common opaB pseudogene (opacity protein) NMC1551 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121634966 Common leuD isopropylmalate isomerase small subunit NMC1179 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 121635142 Common - putative ferredoxin NMC1394 76 COG0348 NapH, Polyferredoxin Energy production and conversion 121634004 Common nusG transcription antitermination protein NusG NMC0118 215 COG0250 NusG, Transcription antiterminator Transcription 121634606 Common purA adenylosuccinate synthetase NMC0765 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 121635338 Common - Insertion element IS1016 transposase NMC1616 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634535 Common - hypothetical protein NMC0691 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 121634515 Common hemH putative ferrochelatase NMC0669 156 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 121634177 Pathogen - hypothetical protein NMC0308 1 None None None 121634412 Common - hypothetical protein NMC0562 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 121634574 Common - hypothetical protein NMC0732 24 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 121635604 Common - putative transglycosylase NMC1920 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121633910 Common gna33 outer membrane lipoprotein Gna33 NMC0010 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 121634115 Common nuoC NADH dehydrogenase subunit C NMC0239 170 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 121635047 Common - putative hydrolase NMC1276 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121634151 Common - hypothetical protein NMC0277 12 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 121634085 Common prlC oligopeptidase A NMC0206 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 121635051 Common lpdA dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) NMC1280 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121635665 Common - hypothetical protein NMC1985 12 None None None 121634734 Common - putative transmembrane transport protein NMC0908 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 121634338 Common - putative transmembrane transport protein NMC0482 105 COG1620 LldP, L-lactate permease Energy production and conversion 121635784 Common - possible lipoprotein NMC2118 131 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 121634407 Common - putative oxidoreductase NMC0556 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121635390 Common speB agmatinase NMC1680 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 121635134 Common recA recombinase A NMC1382 229 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 121635548 Common - hypothetical protein NMC1857 8 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 121635154 Common trpS tryptophanyl-tRNA synthetase NMC1408 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121634142 Pathogen - hypothetical protein NMC0267 1 None None None 121635683 Common - putative permease NMC2005 190 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 121635751 Common mqo malate:quinone oxidoreductase NMC2076 56 COG0579 COG0579, Predicted dehydrogenase General function prediction only 121634575 Common hemE putative uroporphyrinogen decarboxylase NMC0733 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 121635037 Common uvrC excinuclease ABC subunit C NMC1263 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 121635268 Common - putative insertion element is1655 transposase (fragment) NMC1536 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121635298 Common - putative DNA transport competence protein NMC1574 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 121635444 Common murG UDP-N-acetylglucosamine--N-acetylmuramyl-(penta pe pyrophosphoryl-undecaprenol N-acetylglucosamine transferase NMC1742 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 121634391 Common - possible integral membrane protein NMC0539 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 121634164 Common - putative inner membrane trans-acylase protein NMC0291 93 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 121634198 Common - putative DNA-binding protein NMC0331 34 COG2944 COG2944, Predicted transcriptional regulator Transcription 121634616 Common cspA putative transcriptional regulator NMC0776 180 COG1278 CspC, Cold shock proteins Transcription 121634094 Common acpP acyl carrier protein NMC0217 207 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121634187 Common rnpA ribonuclease P NMC0318 52 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 121634905 Common lipB putative lipoate-protein ligase B NMC1111 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 121634063 Common - putative inner membrane protein NMC0179 20 COG1289 COG1289, Predicted membrane protein Function unknown 121634117 Common nuoE NADH dehydrogenase subunit E NMC0241 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 121635716 Common - hypothetical protein NMC2039 25 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 121634758 Common lpdA3 dihydrolipoamide dehydrogenase NMC0933 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121635409 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ NMC1703 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 121634491 Common folC bifunctional folylpolyglutamate synthase/dihydrofolate synthase NMC0644 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 121634406 Common - putative polyamine permease inner membrane protein NMC0555 160 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 121635558 Common - putative invertase/transposase NMC1869 74 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634830 Common fbp fructose-1,6-bisphosphatase NMC1022 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 121635183 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NMC1441 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 121635551 Pathogen - hypothetical protein NMC1862 2 None None None 121634108 Pathogen - hypothetical protein NMC0232 1 None None None 121633936 Pathogen - putative lipoprotein NMC0038 1 None None None 121634006 Common rplA 50S ribosomal protein L1 NMC0120 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 121634419 Common prfC peptide chain release factor 3 NMC0570 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 121635790 Pathogen - putative lipoprotein NMC2124 2 None None None 121633916 Common - hypothetical protein NMC0016 81 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 121634359 Common nqrF Na(+)-translocating NADH-quinone reductase subunit F NMC0505 167 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 121633944 Common rfbA glucose-1-phosphate thymidylyltransferase NMC0046 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 121633975 Common - putative protein export protein NMC0086 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 121634522 Common vsr Putative NmeDIP very-short-patch-repair endonuclease (V.NmeDIP). NMC0678 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 121634202 Common - hypothetical protein NMC0335 84 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 121635207 Common rpoD RNA polymerase sigma factor RpoD NMC1466 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 121634944 Common purM phosphoribosylaminoimidazole synthetase NMC1152 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 121634687 Pathogen - hypothetical protein NMC0854 1 None None None 121635012 Common cmk cytidylate kinase NMC1237 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 121634672 Pathogen - hypothetical protein NMC0838 1 None None None 121635475 Common galM aldose 1-epimerase (mutarotase) NMC1778 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 121635129 Common - putative methyltransferase NMC1376 88 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 121635519 Common - putative periplasmi hypothetical protein NMC1825 47 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121635093 Common - putative transcriptional regulator NMC1328 131 COG1737 RpiR, Transcriptional regulators Transcription 121635303 Common apt adenine phosphoribosyltransferase NMC1580 183 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 121635433 Common acnA aconitate hydratase NMC1729 223 COG1048 AcnA, Aconitase A Energy production and conversion 121635707 Common - putative hydrolase NMC2029 219 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121634742 Common - hypothetical protein NMC0917 74 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121634180 Common - hypothetical protein NMC0311 40 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 121634124 Common nuoK NADH dehydrogenase subunit K NMC0248 158 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 121634719 Common - hypothetical protein NMC0891 22 COG2850 COG2850, Uncharacterized conserved protein Function unknown 121634796 Common - putative surface fibril protein NMC0978 31 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 121634853 Pathogen - hypothetical protein NMC1049 1 None None None 121634551 Common - putative thioredoxin NMC0707 19 None None None 121635101 Common - Putative insertion element IS1106 transposase (fragment) NMC1340 7 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634637 Pathogen - hypothetical protein NMC0803 1 None None None 121634677 Pathogen - hypothetical protein NMC0843 1 None None None 121634670 Common - putative Phage integrase NMC0836 101 None None None 121635315 Common - putative lipase NMC1592 108 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 121634754 Common - hypothetical protein NMC0929 34 COG2938 COG2938, Uncharacterized conserved protein Function unknown 121635224 Common - putative peptidyl-prolyl isomerase NMC1487 131 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 121635322 Common - hypothetical protein NMC1599 5 None None None 121634141 Common - hypothetical protein NMC0265 35 None None None 121634735 Common - putative RNA methylase NMC0909 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 121635138 Common - putative ferredoxin NADP+ reductase NMC1389 105 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 121634168 Common - insertion element IS1655 transposase NMC0297 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121634903 Common bfrA putative bacterioferritin A NMC1108 104 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 121635736 Pathogen - hypothetical protein NMC2059 1 None None None 121635614 Common - hypothetical protein NMC1931 14 COG0824 FcbC, Predicted thioesterase General function prediction only 121635662 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein NMC1982 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 121634216 Pathogen - putative lipoprotein NMC0349 1 None None None 121635584 Pathogen - hypothetical protein NMC1900A 1 None None None 121635135 Common aroD 3-dehydroquinate dehydratase NMC1383 52 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 121635219 Common - hypothetical integral membrane protein NMC1480 48 COG2431 COG2431, Predicted membrane protein Function unknown 121635028 Pathogen - hypothetical protein NMC1254 1 None None None 121634560 Common - putative integral membrane protein NMC0717 72 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121634985 Pathogen - hypothetical protein NMC1200 2 None None None 121633965 Pathogen - hypothetical protein NMC0072 1 None None None 121634445 Common - Adhesin MafB2 NMC0597 7 None None None 121635340 Common lgtF beta-1,4-glucosyltransferase NMC1618 142 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121634231 Common - hypothetical protein NMC0365 25 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 121634382 Common - putative ABC-transporter membrane protein NMC0529 175 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 121635392 Common - hypothetical periplasmic protein NMC1683 2 None None None 121635005 Common nrdA ribonucleotide-diphosphate reductase subunit alpha NMC1226 205 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 121635034 Common rpsF 30S ribosomal protein S6 NMC1260 171 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 121635232 Common - hypothetical protein NMC1495 56 COG1359 COG1359, Uncharacterized conserved protein Function unknown 121635355 Common - hypothetical integral membrane protein NMC1637 40 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 121635259 Common - putative two component sensor kinase NMC1526 74 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121635424 Common - Opa1800 outer membrane protein precursor NMC1719 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121633957 Common rfbB2 dTDP-glucose 4,6-dehydratase NMC0063 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 121634791 Pathogen - putative phage related protein NMC0972 1 None None None 121633996 Common topA DNA topoisomerase I NMC0110 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 121634488 Common purF amidophosphoribosyltransferase NMC0641 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 121635485 Common anmK anhydro-N-acetylmuramic acid kinase NMC1788 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 121633911 Common - putative integral membrane protein NMC0011 95 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 121635474 Common mapA putative maltose phosphorylase NMC1777 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 121634780 Common pntA NAD(P) transhydrogenase subunit alpha NMC0960 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 121634825 Common dedA DedA protein ortholog NMC1016 164 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 121635817 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase NMC2152 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 121634802 Common - putative oxidoreductase NMC0985 179 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 121635382 Common - hypothetical protein NMC1671 39 COG2229 COG2229, Predicted GTPase General function prediction only 121635589 Common atpC F0F1 ATP synthase subunit epsilon NMC1905 174 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 121634917 Pathogen - hypothetical protein NMC1124 1 None None None 121634305 Common - putative hemagglutinin NMC0444 100 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 121635686 Common thrB homoserine kinase NMC2008 68 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 121634138 Common - putative tRNA/rRNA methyltransferase NMC0262 166 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 121634238 Common - hypothetical protein NMC0372 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 121635378 Pathogen - hypothetical protein NMC1667 1 None None None 121635347 Pathogen - hypothetical protein NMC1626 1 None None None 121634113 Common nuoA NADH dehydrogenase I chain A NMC0237 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 121635469 Common - putative cytoplasmic membrane protein NMC1771 64 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 121635577 Common - probable LysR-family transcriptional regulator NMC1891 168 COG0583 LysR, Transcriptional regulator Transcription 121635570 Common ffh signal recognition particle protein NMC1883 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 121635329 Common ans L-asparaginase NMC1606 118 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 121634789 Pathogen - putative phage related protein NMC0970 2 None None None 121635537 Common - octaprenyl-diphosphate synthase NMC1846 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 121634428 Common - hypothetical protein NMC0579 2 None None None 121635057 Common - SUN-family protein NMC1286 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 121635181 Common - putative nuclease NMC1439 67 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 121635719 Common ppc phosphoenolpyruvate carboxylase NMC2042 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 121633913 Common - possible membrane protein NMC0013 47 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 121634339 Common - UDP-2,3-diacylglucosamine hydrolase NMC0483 76 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 121635745 Common gmhA phosphoheptose isomerase NMC2070 123 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 121634772 Pathogen - hypothetical protein NMC0952 1 None None None 121634969 Common leuB 3-isopropylmalate dehydrogenase NMC1182 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 121635320 Common trmA tRNA (uracil-5-)-methyltransferase NMC1597 162 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 121635704 Common - sugar transport PTS system IIA component NMC2026 87 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 121634980 Common ppiA putative peptidyl-prolyl cis-trans isomerase A NMC1195 195 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 121635533 Common - hypothetical protein NMC1841 201 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 121635295 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase NMC1571 216 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 121635626 Common - putative outer membrane peptidase NMC1943 78 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 121635530 Common pgi2 glucose-6-phosphate isomerase 2 NMC1837 194 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 121635553 Pathogen - hypothetical protein NMC1864 1 None None None 121635634 Common - putative sodium-dependent inner membrane transport protein NMC1951 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 121634557 Common dapF putative diaminopimelate epimerase NMC0713 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 121634324 Common - hypothetical protein NMC0468 167 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 121635332 Common dhpS dihydropteroate synthase NMC1609 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 121634598 Common - putative RNA-binding protein NMC0757 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121634143 Common recQ ATP-dependent DNA helicase NMC0269 216 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 121634604 Common - multidrug efflux protein NMC0763 177 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 121634152 Pathogen - hypothetical protein NMC0278 2 None None None 121634032 Common rplR 50S ribosomal protein L18 NMC0148 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 121634127 Common nuoL NADH dehydrogenase subunit L NMC0251 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 121634547 Common - putative D-alanyl-D-alanine-endopeptidase NMC0703 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 121633959 Common rfbC2 dTDP-D-glucose 4,6-dehydratase NMC0065 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 121634083 Common gyrB DNA gyrase subunit B NMC0204 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 121635491 Pathogen - hypothetical protein NMC1795 2 None None None 121634964 Common leuC isopropylmalate isomerase large subunit NMC1176 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 121634192 Pathogen - putative periplasmic protein NMC0324 1 None None None 121634819 Common - hypothetical protein NMC1010 9 COG0456 RimI, Acetyltransferases General function prediction only 121634611 Common nmgII putative modification methylase NMC0771 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 121634866 Common - putative periplasmic protein NMC1065 11 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 121635569 Common - hypothetical inner membrane protein NMC1882 111 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 121634933 Common - putative ABC-transporter ATP-binding protein NMC1140 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121634519 Common rpmI 50S ribosomal protein L35 NMC0674 193 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 121633995 Common - SMG-family protein NMC0109 28 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 121634925 Common - hypothetical protein NMC1132 107 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 121634700 Common - putative phage-related protein NMC0867 14 COG4672 gp18, Phage-related protein Function unknown 121635698 Common porB porin, major outer membrane protein P.I NMC2020 40 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121634690 Common - putative phage related protein NMC0857 38 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 121634294 Common secB preprotein translocase subunit SecB NMC0432 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 121634122 Common nuoI NADH dehydrogenase subunit I NMC0246 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 121635237 Common - hypothetical protein NMC1500 4 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 121634111 Common - putative inner membrane protein NMC0235 17 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 121634976 Common - hypothetical protein NMC1191 122 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 121634417 Common - putative glycosyl transferase NMC0568 36 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121634607 Common htpX heat shock protein HtpX NMC0766 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 121634850 Pathogen - putative DNA-binding protein (phage related) NMC1045 2 None None None 121635117 Common - putative aminopeptidase NMC1363 202 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 121635499 Common - hypothetical protein NMC1803 2 None None None 121634027 Common rplX 50S ribosomal protein L24 NMC0143 168 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 121635339 Common fabF2 3-oxoacyl-(acyl carrier protein) synthase II NMC1617 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121634179 Common plsX fatty acid/phospholipid synthesis protein NMC0310 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 121635586 Common lgtA lacto-N-neotetraose biosynthesis glycosyl tranferase NMC1902 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121634334 Common hemC porphobilinogen deaminase NMC0478 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 121634252 Common - putative phosphatase NMC0386 153 COG0546 Gph, Predicted phosphatases General function prediction only 121635501 Pathogen - hypothetical protein NMC1805 1 None None None 121634431 Common - putative deoxyribonucleotide triphosphate pyrophosphatase NMC0582 233 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 121635364 Common tonB TonB protein NMC1650 21 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 121634436 Pathogen - hypothetical protein NMC0587 1 None None None 121635262 Common metZ O-succinylhomoserine sulfhydrolase NMC1530 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 121633950 Common siaB acylneuraminate cytidylyltransferase NMC0053 66 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 121635140 Common - hypothetical protein NMC1392 78 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 121635091 Pathogen - hypothetical protein NMC1325 1 None None None 121634265 Common - hypothetical protein NMC0400 23 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121635792 Common - insertion element IS1016 transposase NMC2126 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634423 Common hisH imidazole glycerol phosphate synthase subunit HisH NMC0574 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 121634787 Common - putative amidase NMC0967 5 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 121635725 Common - putative permease NMC2048 18 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 121635652 Common - putative adhesin/invasin NMC1969 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 121635168 Pathogen - conserved hypothetical protein (fragment) NMC1424 4 None None None 121635788 Common - hypothetical protein NMC2122 13 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 121634644 Common - spermidine synthase NMC0810 56 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 121634505 Common holA DNA polymerase III subunit delta NMC0658 76 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 121634500 Common comL competence lipoprotein NMC0653 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 121635442 Common ddl D-alanine--D-alanine ligase NMC1740 216 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 121635045 Common - hypothetical protein NMC1274 131 COG1678 COG1678, Putative transcriptional regulator Transcription 121635640 Common polA DNA polymerase I NMC1957 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 121635761 Pathogen - hypothetical protein NMC2087 1 None None None 121634736 Common - hypothetical protein NMC0910 30 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 121634627 Common rdgC recombination associated protein NMC0791 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 121634036 Common secY preprotein translocase subunit SecY NMC0152 249 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 121634370 Common gcvH glycine cleavage system protein H NMC0517 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 121635572 Common - putative thiol:disulphide interchange protein NMC1885 69 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121635547 Common - conserved hypothetical protein, possible peptidase NMC1856 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 121633942 Common - putative inner membrane transport protein NMC0044 42 COG1297 COG1297, Predicted membrane protein Function unknown 121634812 Common - hypothetical protein NMC1001 3 None None None 121634288 Common - putative oxidoreductase NMC0426 98 COG0431 COG0431, Predicted flavoprotein General function prediction only 121635198 Common rfaF ADP-heptose:LPS heptosyltransferase II NMC1456 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 121635024 Common tig trigger factor NMC1250 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 121635786 Pathogen - putative periplasmic protein NMC2120 1 None None None 121634654 Common cysA putative sulphate permease ATP-binding protein NMC0820 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 121634887 Pathogen - hypothetical protein NMC1089 1 None None None 121635084 Common - conserved hypothetical DNA-binding protein NMC1314 138 COG1959 COG1959, Predicted transcriptional regulator Transcription 121634890 Common cysJ putative sulphite reductase alpha subunit NMC1092 106 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 121634310 Common - putative Hemagglutinin/hemolysin-related protein NMC0450 11 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 121634315 Pathogen - hypothetical protein NMC0456 1 None None None 121635415 Pathogen - hypothetical protein NMC1710 2 None None None 121634585 Common ppiB putative peptidyl-prolyl cis-trans isomerase B NMC0744 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 121634272 Common aroK putative shikimate kinase NMC0407 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 121635592 Common atpA F0F1 ATP synthase subunit alpha NMC1908 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 121634873 Common - hypothetical protein NMC1072 7 COG3779 COG3779, Uncharacterized protein conserved in bacteria Function unknown 121634345 Common - putative thiol:disulphide interchange protein NMC0490 71 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121635209 Common lbpB lactoferrin-binding protein NMC1469 4 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 121634846 Common - hypothetical protein NMC1040 97 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 121634040 Common rpsK 30S ribosomal protein S11 NMC0156 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 121634361 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D NMC0507 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 121635018 Common - putative nucleotide-binding protein NMC1243 98 COG1485 COG1485, Predicted ATPase General function prediction only 121634073 Common lpxB lipid-A-disaccharide synthase NMC0191 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 121634666 Common - hypothetical protein NMC0832 90 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 121635248 Common - hypothetical protein NMC1512 7 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 121635040 Pathogen - hypothetical protein NMC1268 1 None None None 121634899 Common guaB inositol-5-monophosphate dehydrogenase NMC1103 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 121634833 Common folB putative dihydroneopterin aldolase NMC1027 89 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 121635563 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase NMC1874 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 121635454 Common - putative small periplasmic protein NMC1754 4 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 121635590 Common atpD F0F1 ATP synthase subunit beta NMC1906 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 121634328 Common nth putative endonuclease III NMC0472 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 121635463 Common putP sodium/proline symporter NMC1765 178 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 121635426 Common - putative oxidoreductase NMC1721 161 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 121634684 Common - Transcriptional regulator NMC0850 25 COG2932 COG2932, Predicted transcriptional regulator Transcription 121634593 Common - hypothetical protein NMC0752 91 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 121634360 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E NMC0506 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 121635599 Common - putative chromosome segregation proteins NMC1915 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 121634365 Common - hypothetical protein NMC0512 29 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 121634472 Pathogen - hypothetical protein NMC0625 1 None None None 121634174 Common fabD putative malonyl CoA-acyl carrier protein transacylase NMC0305 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 121634946 Common ribA putative GTP cyclohydrolase II NMC1155 190 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 121634798 Common - putative acyl-CoA dehydrogenase NMC0981 130 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121634255 Common dnaE putative DNA polymerase III, alpha subunit NMC0389 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 121635127 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit NMC1374 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 121635702 Common ptsI phosphoenolpyruvate-protein phosphotransferase NMC2024 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 121634384 Common rplS 50S ribosomal protein L19 NMC0531 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 121634056 Common - putative outer membrane protein NMC0172 61 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 121635517 Common - D-tyrosyl-tRNA deacylase NMC1823 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 121634527 Pathogen - hypothetical protein NMC0683 1 None None None 121634494 Common - putative amino acid permease ATP-binding protein NMC0647 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121634744 Common rpmJ 50S ribosomal protein L36 NMC0919 60 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 121634204 Common - hypothetical protein NMC0337 137 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121634061 Common uppS putative undecaprenyl diphosphate synthase NMC0177 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 121634544 Common - putative regulator NMC0700 29 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 121634481 Common nusB transcription antitermination protein NusB NMC0634 121 COG0781 NusB, Transcription termination factor Transcription 121634682 Pathogen - hypothetical protein NMC0848 1 None None None 121634831 Common - hypothetical protein NMC1024 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 121635376 Pathogen - putative integral membrane protein NMC1664 1 None None None 121634851 Common - putative phage transposase NMC1046 23 None None None 121634410 Common rho transcription termination factor Rho NMC0560 202 COG1158 Rho, Transcription termination factor Transcription 121634591 Common ftsH putative ATP-dependent zinc metallopeptidase NMC0750 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 121634717 Pathogen - putative integral membrane protein NMC0889 1 None None None 121634674 Common - putative phage related protein NMC0840 10 None None None 121635810 Common ftsE ABC transporter ATP-binding protein NMC2145 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 121634014 Common - elongation factor Tu NMC0128 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 121634800 Pathogen - hypothetical protein NMC0983 1 None None None 121634569 Common upp uracil phosphoribosyltransferase NMC0727 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 121634509 Common rpoH RNA polymerase factor sigma-32 NMC0663 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 121635579 Common - putative IS1106 transposase (fragment) NMC1894 32 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121635317 Common gcvP glycine dehydrogenase NMC1594 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 121635446 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NMC1745 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 121634119 Pathogen - hypothetical protein NMC0243 2 None None None 121634524 Common - Putative type II restriction enzyme NmeDIP NMC0680 16 None None None 121634307 Pathogen - conservative hypothetical protein NMC0447 1 COG3792 COG3792, Uncharacterized protein conserved in bacteria Function unknown 121633938 Common dksA putative DnaK suppressor protein NMC0040 146 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 121634092 Common - putative inner membrane transport protein NMC0215 75 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 121635145 Common - hypothetical protein NMC1397 32 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121634724 Common icd putative isocitrate dehydrogenase NMC0897 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 121635349 Common - putative integral membrane protein NMC1630 41 COG1620 LldP, L-lactate permease Energy production and conversion 121634189 Common dnaA putative chromosomal replication initiator protein NMC0320 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 121633925 Pathogen - TspB protein NMC0025 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 121634101 Common - hypothetical protein NMC0225 144 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 121634493 Common - hypothetical protein NMC0646 6 None None None 121634222 Common orn oligoribonuclease NMC0355 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 121635400 Common - hypothetical protein NMC1693 204 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 121635524 Common gloA lactoylglutathione lyase NMC1830 134 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121633918 Common - putative inner membrane protein NMC0018 179 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 121635032 Common rpsR 30S ribosomal protein S18 NMC1258 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 121634577 Common - putative periplasmic protein NMC0735 35 COG3439 COG3439, Uncharacterized conserved protein Function unknown 121635257 Common gpm phosphoglycerate mutase NMC1524 134 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 121634404 Common - putative polyamine permease ATP-binding protein NMC0553 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121633934 Common pilT putative pilus retraction protein NMC0036 217 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 121635250 Pathogen - hypothetical protein NMC1514 2 None None None 121634357 Common - putative periplasmic protein NMC0503 26 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 121635675 Common - putative psedouridine synthase NMC1997 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121634440 Pathogen - hypothetical protein NMC0592 1 None None None 121635472 Common - putative transposase for IS1106A3 NMC1775 41 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121635327 Common prfA peptide chain release factor 1 NMC1604 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 121634166 Pathogen - putative inner membrane protein NMC0294 1 None None None 121635345 Common thyA thymidylate synthase NMC1624 145 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 121634804 Common - putative transposase for IS1106 NMC0988 39 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121635607 Common regG ClpXP protease specificity-enhancing factor NMC1924 64 COG2969 SspB, Stringent starvation protein B General function prediction only 121634029 Common rpsN 30S ribosomal protein S14 NMC0145 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 121635163 Common - putative membrane peptidase NMC1418 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 121635647 Common fetB putative membrane transport solute-binding protein NMC1964 61 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 121634131 Common ispA geranyltranstransferase NMC0255 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 121635384 Pathogen - hypothetical protein NMC1673 1 None None None 121635806 Common gltX glutamyl-tRNA synthetase NMC2141 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 121634919 Common - putative ABC transporter ATP-binding protein NMC1126 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121634782 Common - putative integral membrane protein NMC0962 68 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 121634425 Common fbpC putative iron-uptake permease ATP-binding protein NMC0576 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121634396 Common - putative nucleotide-binding protein NMC0545 226 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 121635600 Common - aromatic acid decarboxylase NMC1916 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 121635520 Common - hypothetical protein NMC1826 73 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 121634244 Common fhs putative formate--tetrahydrofolate ligase NMC0378 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 121635019 Common ndk nucleoside diphosphate kinase NMC1244 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 121634618 Common - hypothetical protein NMC0778 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 121635110 Common fis factor-for-inversion-stimulation protein NMC1353 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 121635616 Common - putative periplasmic/outer membrane protein NMC1933 93 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 121635266 Common fumA fumarate hydratase NMC1534 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 121634351 Common - putative transcriptional regulator NMC0497 53 COG2932 COG2932, Predicted transcriptional regulator Transcription 121635106 Common pepN aminopeptidase N NMC1347 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 121634219 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase NMC0352 211 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 121635399 Common glr glutamate racemase NMC1692 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 121635362 Common exbD biopolymer transport protein NMC1648 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 121635540 Common - hypothetical protein NMC1849 133 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 121635775 Common argG argininosuccinate synthase NMC2106 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 121635217 Common glnS glutaminyl-tRNA synthetase NMC1478 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 121633984 Common pyrB aspartate carbamoyltransferase catalytic subunit NMC0098 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 121635781 Common - putative periplasmic protein NMC2113 93 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 121635007 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase NMC1231 117 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 121635021 Common - putative lipoprotein NMC1246 72 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 121634668 Common - hypothetical protein NMC0834 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121633973 Pathogen - putative inner membrane protein NMC0084 1 None None None 121633989 Common fmt methionyl-tRNA formyltransferase NMC0103 221 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 121634261 Common pglD pilin glycosylation protein NMC0396 154 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121634901 Common - putative transcriptional regulator NMC1106 38 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 121634910 Common - uracil-DNA glycosylase NMC1116 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 121634978 Common - putative type III restriction-modification system endonuclease protein NMC1193 40 COG3587 COG3587, Restriction endonuclease Defense mechanisms 121634455 Pathogen - hypothetical protein NMC0607 1 None None None 121635695 Common truA tRNA pseudouridine synthase A NMC2017 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 121634512 Pathogen - putative integral membrane protein NMC0666 1 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 121634356 Common grpE probable heat shock protein NMC0502 220 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 121635354 Pathogen - hypothetical protein NMC1636 1 None None None 121635508 Common - putative ABC transporter ATP-binding protein NMC1812 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 121634929 Pathogen - putative periplasmic protein NMC1136 1 None None None 121635582 Common - hypothetical protein NMC1899 198 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 121635230 Common argF ornithine transcarbamoylase NMC1493 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 121635158 Common - hypothetical protein NMC1412 27 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 121634609 Common pyrF orotidine 5'-phosphate decarboxylase NMC0768 159 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 121635319 Common tyrB aromatic amino acid aminotransferase NMC1596 75 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121635112 Common - putative ATP-dependent RNA helicase NMC1355 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121635506 Common aroE shikimate dehydrogenase NMC1810 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 161723298 Common ribC riboflavin synthase subunit alpha NMC1148 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 121634296 Common argC N-acetyl-gamma-glutamyl-phosphate reductase NMC0434 217 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 121634827 Common ggt putative gamma-glutamyltranspeptidase NMC1018 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 121635153 Pathogen - hypothetical protein NMC1407 1 None None None 121634376 Common - putative electron transfer flavoprotein-ubiquinone oxidoreductase NMC0523 112 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 121634844 Common argB putative acetylglutamate kinase NMC1038 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 121635305 Common - probable protease NMC1582 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 121634703 Common - Neisseria meningitidis phage 2120.; ORF 4 NMC0870 23 COG4733 COG4733, Phage-related protein, tail component Function unknown 121634613 Common rfaD putative ADP-L-glycero-D-mannoheptose epimerase NMC0773 229 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121635271 Common - hypothetical protein NMC1545 74 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 121635269 Common thiD phosphomethylpyrimidine kinase NMC1538 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 121634433 Common ppa putative inorganic pyrophosphatase NMC0584 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 121634284 Common - lipid A biosynthesis lauroyl acyltransferase NMC0421 84 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 121635096 Common zwf glucose-6-phosphate 1-dehydrogenase NMC1331 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 121635808 Common - putative oxidoreductase NMC2143 101 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 121635016 Common adhC alcohol dehydrogenase class-III NMC1241 198 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 121634210 Common argA N-acetylglutamate synthase NMC0343 196 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 121635693 Common nlaB 1-acyl-SN-glycerol-3-phosphate acyltransferase NMC2015 182 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 121635188 Pathogen - hypothetical protein NMC1446 1 None None None 121634075 Pathogen - hypothetical protein NMC0194 1 None None None 121634484 Common rnc ribonuclease III NMC0637 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 121634470 Common - hypothetical protein NMC0623 92 COG2835 COG2835, Uncharacterized conserved protein Function unknown 121634927 Common - putative ABC-transporter ATP-binding protein NMC1134 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121635176 Common - hypothetical protein NMC1433 139 COG1354 COG1354, Uncharacterized conserved protein Function unknown 121635334 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NMC1611 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 121634880 Common - putative RNA methyltransferase NMC1081 190 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 121635669 Common - hypothetical protein NMC1991 23 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 121634539 Common - hypothetical protein NMC0695 70 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121635539 Common rpmA 50S ribosomal protein L27 NMC1848 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 121635734 Pathogen - putative integral membrane protein NMC2057 1 COG1714 COG1714, Predicted membrane protein/domain Function unknown 121634962 Common radC DNA repair protein RadC NMC1174 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 121635043 Common - hypothetical secreted lysine-rich protein NMC1271 145 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 121633915 Common glmU bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); glucosamine-1-phosphate N-acetyltransferase NMC0015 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 121635727 Common thiE thiamin-phosphate pyrophosphorylase NMC2050 199 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 121634340 Common - hypothetical protein NMC0484 184 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 121635535 Common pilF type IV pilus assembly protein NMC1844 211 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 121635597 Pathogen atpI putative ATP synthase I NMC1913 1 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 121634967 Common - DNA modification methylase NMC1180 129 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 121635688 Common - amino-acid transport protein NMC2010 35 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 121634878 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha NMC1078 197 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 121635293 Common - hypothetical protein NMC1569 37 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 121634058 Common - putative inner membrane protease NMC0174 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 121634871 Common hscA chaperone protein HscA NMC1070 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121635493 Common - hypothetical protein NMC1797 3 None None None 121634578 Common - putative periplasmic protein NMC0736 98 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121634363 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B NMC0509 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 121634956 Common - hypothetical protein NMC1166 10 None None None 121634394 Common tatC putative sec-independent protein translocase component NMC0542 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 121634738 Common miaA putative tRNA delta(2)-isopentenylpyrophosphate transferase NMC0912 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 121635555 Pathogen - TspB protein NMC1866 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 121634316 Common - hypothetical protein NMC0457 4 None None None 121634081 Common - putative ferredoxin NMC0200 128 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 121635650 Common - hypothetical protein NMC1967 17 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 121635717 Common - hypothetical protein NMC2040 2 None None None 121635055 Common - SpoU methylase family protein NMC1284 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 121634145 Common - hypothetical protein NMC0271 59 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 121634129 Common nuoN NADH dehydrogenase subunit N NMC0253 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 121634270 Common - hypothetical protein NMC0405 79 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 121634236 Common carA carbamoyl phosphate synthase small subunit NMC0370 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 121634892 Common cysD sulfate adenylyltransferase subunit 2 NMC1094 126 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 121634379 Pathogen - putative outer membrane protein NMC0526 1 None None None 121635413 Common - putative integral membrane protein NMC1708 50 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 121635398 Pathogen tbpB transferrin-binding protein B NMC1691 3 None None None 121635624 Pathogen - hypothetical protein NMC1941 1 None None None 121635465 Common - putative transposase fragment NMC1767 50 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635239 Common hisC histidinol-phosphate aminotransferase NMC1502 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 121635714 Common rpsI 30S ribosomal protein S9 NMC2037 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 121634322 Common - hypothetical protein NMC0466 104 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 121635679 Common - hypothetical protein NMC2001 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 121635488 Pathogen - hypothetical protein NMC1791 1 None None None 121634722 Common parA ParA protein NMC0895 200 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 121634347 Pathogen - putative integral membrane protein NMC0493 2 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 121634635 Common - hypothetical protein NMC0801 2 None None None 121634415 Common - putative periplasmic carrier protein NMC0566 74 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 121635080 Common truB tRNA pseudouridine synthase B NMC1309 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 121634586 Common - putative transmembrane transport protein NMC0745 132 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 121634047 Common oxyR putative hydrogen peroxide-inducible genes activator NMC0163 190 COG0583 LysR, Transcriptional regulator Transcription 121634367 Common - hypothetical protein NMC0514 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 121634286 Common - probable Insertion element IS1016 transposase NMC0423 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121633949 Common siaC N-acetylneuraminic acid synthetase NMC0052 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 121635403 Common - hypothetical protein NMC1697 129 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 121633978 Pathogen - putative inner membrane protein NMC0092 1 None None None 121635035 Common trxB thioredoxin reductase NMC1261 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 121635435 Common ddpX putative D-alanyl-d-alanine dipeptidase NMC1731 39 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 121634710 Pathogen - putative transcription regulator NMC0880 2 COG2336 MazE, Growth regulator Signal transduction mechanisms 121634278 Common ponA penicillin-binding protein 1 NMC0414 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 121634326 Common - putative integral membrane protein NMC0470 54 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 121635133 Common - Putative transposase for IS1655 NMC1381 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121635452 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase NMC1751 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 121635649 Common - putative inner membrane transport protein NMC1966 88 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 121634263 Common - putative hydrolase, haloacid dehalogenase-like hydrolase NMC0398 16 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 121633940 Pathogen - hypothetical protein NMC0042 1 None None None 121634820 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit NMC1011 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 121634814 Pathogen - hypothetical protein NMC1005 1 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 121634657 Pathogen - hypothetical protein NMC0823 1 None None None 121634994 Common mltB murein hydrolase NMC1212 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 121634103 Common - hypothetical protein NMC0227 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 121634761 Common sucD succinyl-CoA synthetase subunit alpha NMC0936 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 121634625 Common dcd deoxycytidine triphosphate deaminase NMC0789 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 121634646 Common panC pantoate--beta-alanine ligase NMC0812 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 121634196 Common - putative Modification methylase DpnIIB NMC0328 134 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 121635065 Common - iron/sulphur-binding oxidoreductase NMC1294 148 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 121634242 Common - putative sugar-phosphate nucleotidyl transferase NMC0376 217 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 121635778 Pathogen - putative periplasmic protein NMC2109 1 None None None 121635249 Common - AraC-family transcriptional regulator NMC1513 125 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 121634652 Common - putative D-alanyl-D-alanine carboxypeptidase NMC0818 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 121635632 Common groES co-chaperonin GroES NMC1949 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 121634503 Common - hypothetical protein NMC0656 179 COG1496 COG1496, Uncharacterized conserved protein Function unknown 121634010 Common rpoC DNA-directed RNA polymerase subunit beta' NMC0124 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 121635200 Common - hypothetical outer membrane protein NMC1458 71 COG1881 COG1881, Phospholipid-binding protein General function prediction only 121634034 Common rpmD 50S ribosomal protein L30 NMC0150 50 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 121634931 Common - putative peptidyl-prolyl cis-trans isomerase NMC1138 110 None None None 121634762 Common - hypothetical protein NMC0938 31 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635022 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NMC1247 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 121634614 Common clpA putative ATP-dependent protease ATP-binding protein NMC0774 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 121635651 Common - putative ABC transporter ATP-binding subunit NMC1968 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 121634373 Common - hypothetical protein NMC0520 49 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 121634467 Common maeA putative malate oxidoreductase NMC0620 202 COG0281 SfcA, Malic enzyme Energy production and conversion 121635086 Common - scaffold protein NMC1317 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 121635068 Common - putative integral membrane transporter NMC1297 88 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 121635732 Common - putative transferase NMC2055 128 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 121634739 Pathogen - hypothetical protein NMC0913 1 None None None 121634648 Common lolB outer membrane lipoprotein LolB NMC0814 24 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 121635090 Pathogen - putative transposase (fragment) NMC1323 2 None None None 121634623 Common - hypothetical protein NMC0784 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 121635143 Common tkt transketolase NMC1395 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 121635674 Common - putative DNA transport competence protein NMC1996 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 121634721 Common - putative ParB protein NMC0893 3 None None None 121635694 Common - hypothetical protein NMC2016 138 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 121634816 Common - hypothetical protein NMC1007 61 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 121634531 Pathogen - hypothetical protein NMC0687 2 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 121634602 Common - putative tetR-family transcriptional regulator NMC0761 54 COG1309 AcrR, Transcriptional regulator Transcription 121635423 Common - putative transposase NMC1718 74 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635102 Common - Remnant of Insertion element IS1106A3 transposase NMC1341 13 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634105 Common - hypothetical protein NMC0229 100 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 121635645 Common trmE tRNA modification GTPase TrmE NMC1962 220 COG0486 ThdF, Predicted GTPase General function prediction only 121634277 Common pilM putative pilus assembly protein NMC0412 62 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 121635165 Common - hypothetical protein NMC1420 216 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 121634634 Pathogen - hypothetical protein NMC0800 1 None None None 121633927 Pathogen - putative periplasmic protein NMC0028 1 None None None 121634596 Common - hypothetical protein NMC0755 81 COG1469 COG1469, Uncharacterized conserved protein Function unknown 121634077 Common - putative outer membrane lipoprotein NMC0196 62 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 121634995 Common - putative oxidoreductase NMC1213 17 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121635457 Common - hypothetical protein NMC1757 94 COG1565 COG1565, Uncharacterized conserved protein Function unknown 121634989 Common - putative periplasmic protein NMC1204 25 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 121635292 Common - hypothetical protein NMC1568 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 121635580 Common - hypothetical protein NMC1896 45 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 121634693 Pathogen - hypothetical protein NMC0860 1 None None None 121634746 Common metF 5,10-methylenetetrahydrofolate reductase NMC0921 145 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 121634269 Common - hypothetical protein NMC0404 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 121634321 Common - hypothetical protein NMC0465 13 None None None 121634821 Common - hypothetical protein NMC1012 4 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 121634044 Common minC septum formation inhibitor NMC0160 92 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 121633908 Common glmS D-fructose-6-phosphate amidotransferase NMC0008 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 121635596 Common atpB F0F1 ATP synthase subunit A NMC1912 191 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 121634589 Common - hypothetical protein NMC0748 69 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 121634372 Common - putative regulatory protein NMC0519 26 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 121634232 Common - hypothetical protein NMC0366 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 121634148 Common - hypothetical protein NMC0274 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 121634730 Common - putative transposase for IS1655 NMC0904 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121635130 Common mutL DNA mismatch repair protein NMC1378 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 121634660 Common dnaB replicative DNA helicase NMC0826 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 121635460 Common - hypothetical lysine-rich membrane protein NMC1762 3 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 121634542 Pathogen - hypothetical protein NMC0698 1 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 121635622 Common - putative transcriptional regulator NMC1939 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121635436 Common prpC methylcitrate synthase NMC1732 194 COG0372 GltA, Citrate synthase Energy production and conversion 121634864 Common - ABC-transporter ATP-binding protein (pseudogene) NMC1062 63 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 121635071 Common - hypothetical protein NMC1300 46 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 121635512 Common - hypothetical protein NMC1816 165 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 121633982 Pathogen - putative lipoprotein NMC0096 1 None None None 121635059 Common - putative aldehyde dehydrogenase NMC1288 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121634876 Common - hypothetical protein NMC1076 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 121635195 Common - hypothetical protein NMC1453 204 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121634048 Common valS valyl-tRNA synthetase NMC0164 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635813 Common pgk phosphoglycerate kinase NMC2148 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 121634110 Common - putative IS1016 transposase NMC0234 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634297 Pathogen - hypothetical protein NMC0435 1 None None None 121634378 Common - putative transposase NMC0525 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634342 Common - putative pilin NMC0487 55 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121634038 Pathogen rpmJ 50S ribosomal protein L36 NMC0154 1 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 121634483 Common - hypothetical protein NMC0636 7 COG4859 COG4859, Uncharacterized protein conserved in bacteria Function unknown 121634984 Common - hypothetical protein NMC1199 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 121633952 Common ctrA capsule polysaccharide export outer membrane protein NMC0055 64 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 121634280 Common cyc putative cytochrome C NMC0416 55 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121635179 Common - hypothetical protein NMC1437 4 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 121635075 Pathogen - putative membrane lipoprotein NMC1304 1 None None None 121634020 Common rpsS 30S ribosomal protein S19 NMC0136 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 121635557 Common - hypothetical protein NMC1868 9 COG4128 Zot, Zonula occludens toxin General function prediction only 121635448 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase NMC1747 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 121635070 Common nadE NH(3)-dependent NAD synthetase NMC1299 210 COG0171 NadE, NAD synthase Coenzyme metabolism 121635480 Common rmpM outer membrane protein class 4 NMC1783 138 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 121635054 Common - inositol monophosphate family protein NMC1283 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 121635783 Common prfB peptide chain release factor 2 NMC2116 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 121635618 Common - putative periplasmic transport protein NMC1935 72 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 121635668 Common vsr patch repair protein NMC1990 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 121635302 Common gmk guanylate kinase NMC1579 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 121635243 Common - putative transposase for IS1106A3 NMC1506 41 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121635441 Common ftsQ cell division protein NMC1739 82 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 121634451 Pathogen - hypothetical protein NMC0603 1 None None None 121635155 Common clpB ClpB protein NMC1409 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 121634086 Common - putative integral membrane protein NMC0207 61 COG1971 COG1971, Predicted membrane protein Function unknown 121635335 Common - hypothetical protein NMC1613 8 COG4899 COG4899, Uncharacterized protein conserved in bacteria Function unknown 121634070 Common pdxA pyridoxal phosphate biosynthetic protein NMC0186 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 121635119 Common greA transcription elongation factor NMC1365 197 COG0782 GreA, Transcription elongation factor Transcription 121635743 Common - hypothetical protein NMC2068 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 121634767 Common trpG anthranilate synthase component II NMC0947 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 121634642 Common - hypothetical protein NMC0808 213 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121634879 Common - hypothetical protein NMC1080 185 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 121635048 Common proS prolyl-tRNA synthetase NMC1277 242 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635739 Common cysS cysteinyl-tRNA synthetase NMC2062 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121634843 Common - hypothetical protein NMC1037 29 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 121634859 Common - transposase for IS1655 NMC1055 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121634565 Common holB DNA polymerase III subunit delta' NMC0722 217 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 121635274 Common nor nitric oxide reductase NMC1548 72 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 121635097 Common edd phosphogluconate dehydratase NMC1332 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 161723299 Common pheS phenylalanyl-tRNA synthetase subunit alpha NMC0676 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 121634257 Pathogen - hypothetical protein NMC0392 1 None None None 121634922 Pathogen - hypothetical protein NMC1129 1 None None None 121635496 Common - hypothetical protein NMC1800 13 None None None 121634051 Common - putative amino-acid transporter NMC0167 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 121635309 Common hmbR pseudogene (haemoglobin receptor) NMC1586 84 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121634889 Common cysI putative sulphite reductase beta subunit NMC1091 145 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 121635419 Pathogen - conserved hypothetical protein (fragment) NMC1714 1 None None None 121635804 Common - putative acetyltransferase NMC2139 22 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 121634438 Common - Ribonuclease inhibitor barstar NMC0589 6 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 121634745 Common rpmE2 50S ribosomal protein L31 type B NMC0920 79 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 121634908 Common - putative periplasmic protein NMC1114 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 121634435 Pathogen mafB3 putative adhesin NMC0586 1 None None None 121634951 Pathogen - hypothetical protein NMC1160 1 None None None 121634939 Common - hypothetical protein NMC1147 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 121634190 Common dnaN DNA polymerase III subunit beta NMC0321 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 121634639 Common - hypothetical protein NMC0805 3 None None None 121635235 Common - putative lipoprotein NMC1498 115 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 121634172 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein NMC0303 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 121634290 Common - putative two-component system response regulator (pseudogene) NMC0428 11 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121635009 Common - hypothetical protein NMC1233 35 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121634212 Common pyrE orotate phosphoribosyltransferase NMC0345 108 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 121634771 Common - hypothetical protein NMC0951 5 None None None 121634971 Common aspA aspartate ammonia-lyase NMC1185 232 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 121635352 Common mtrC membrane fusion protein NMC1634 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121635678 Common - hypothetical protein NMC2000 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 121635255 Common - C-5 cytosine-specific DNA methylase NMC1520 130 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 121633970 Pathogen - hypothetical protein NMC0081 1 None None None 121635367 Pathogen - possible membrane protein NMC1653 1 None None None 121635341 Common rfaK alpha 1,2 N-acetylglucosamine transferase NMC1619 210 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121635682 Common - hypothetical protein NMC2004 40 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 121635615 Common - hypothetical protein NMC1932 6 None None None 121634568 Common - hypothetical protein NMC0726 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 121634383 Common - putative ABC-transporter ATP-binding protein NMC0530 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 121635795 Common - hypothetical protein NMC2130 3 None None None 121635031 Common rplI 50S ribosomal protein L9 NMC1257 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 121634354 Common ubiB putative ubiquinone biosynthesis protein UbiB NMC0500 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 121635631 Common groEL chaperonin GroEL NMC1948 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 121634510 Common lnt apolipoprotein N-acyltransferase NMC0664 153 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 121635489 Common - hypothetical protein NMC1792 2 None None None 121634247 Common tyrS putative tyrosyl-tRNA synthetase NMC0381 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635202 Common - hypothetical protein NMC1460 6 None None None 121633987 Common - putative periplasmic protein (possibly peptidoglycan-binding) NMC0101 47 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 121634461 Common - coproporphyrinogen III oxidase NMC0613 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 121635225 Common holC DNA polymerase III chi subunit NMC1488 28 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 121634318 Pathogen - putative periplasmic protein NMC0459 1 None None None 121635000 Common eno phosphopyruvate hydratase NMC1220 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 121634937 Common rpe putative ribulose-phosphate 3-epimerase NMC1145 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 121635380 Common - hypothetical protein NMC1669 22 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 121634234 Pathogen - putative integral membrane protein NMC0368 1 None None None 121635636 Pathogen - putative lipoprotein NMC1953 1 None None None 121634805 Common - putative phage integrase NMC0992 80 None None None 121634447 Common - hypothetical protein NMC0599 14 None None None 121634282 Common - hypothetical protein NMC0418 186 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 121634001 Common - putative ferredoxin NMC0115 118 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 121634397 Common hisE putative phosphoribosyl-ATP cyclohydrolase NMC0546 181 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 121635434 Common - putative integral membrane protein NMC1730 11 COG5505 COG5505, Predicted integral membrane protein Function unknown 121635466 Common xthA exodeoxyribonuclease III NMC1768 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 121635691 Common - pseudogene (putative acetyltransferase) NMC2013 16 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 121634945 Pathogen - hypothetical protein NMC1154 1 None None None 121634468 Common lpxK tetraacyldisaccharide 4'-kinase NMC0621 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 121633963 Common gltS sodium/glutamate symport carrier protein NMC0069 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 121634913 Common - putative transposase NMC1120 54 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635756 Common tsf elongation factor Ts NMC2081 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 121634454 Pathogen - conserved hypothetical protein (fragment) NMC0606 1 None None None 121634403 Common rpsO 30S ribosomal protein S15 NMC0552 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 121634579 Common recB putative exodeoxyribonuclease V beta chain NMC0737 222 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 121634306 Pathogen - hypothetical protein NMC0445 1 None None None 121635186 Common - putative integral membrane protein NMC1444 81 None None None 121635797 Common etfA electron transfer flavoprotein alpha-subunit NMC2132 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 121634857 Pathogen - hypothetical protein NMC1053 1 None None None 121634017 Common rplD 50S ribosomal protein L4 NMC0133 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 121635405 Common - MutT-related protein NMC1699 143 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 121634600 Pathogen - hypothetical protein NMC0759 1 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 121635523 Common tspA Neisseria-specific antigen protein, TspA NMC1829 24 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 121634226 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase NMC0360 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 121634157 Pathogen tspB TspB protein NMC0283 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 121635514 Pathogen - hypothetical protein NMC1819 1 None None None 121634182 Common - hypothetical protein NMC0313 31 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 121634838 Common proA gamma-glutamyl phosphate reductase NMC1032 190 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 121634498 Common iga IgA1 protease NMC0651 15 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121635527 Common ilvE branched-chain amino acid aminotransferase NMC1833 210 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 121635385 Common - hypothetical protein NMC1674 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121635606 Common - hypothetical protein NMC1922 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 121635328 Common - hypothetical protein NMC1605 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 121635767 Pathogen - hypothetical protein NMC2093 1 None None None 121633904 Common fbp peptidyl-prolyl cis-trans isomerase NMC0004 153 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 121634541 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase NMC0697 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121633920 Common pilB peptide methionine sulfoxide reductase NMC0020 207 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 121635776 Common - hypothetical protein NMC2107 3 None None None 121635504 Common - putative integral membrane signal transducer protein NMC1808 109 None None None 121635030 Common - hypothetical protein NMC1256 122 COG0730 COG0730, Predicted permeases General function prediction only 121635281 Common - hypothetical protein NMC1555 158 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 121634869 Common - putative oxidoreductase NMC1068 38 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 121635712 Common - hypothetical protein NMC2035 104 COG0327 COG0327, Uncharacterized conserved protein Function unknown 121634207 Common fetB2 putative ferric enterobactin transporter binding protein NMC0340 49 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 121634793 Pathogen - putative phage related protein NMC0974 1 None None None 121635411 Common pheA chorismate mutase NMC1705 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 121635307 Common - hypothetical protein NMC1584 35 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 121634251 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NMC0385 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 121633991 Common - hypothetical protein NMC0105 20 None None None 121634068 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NMC0184 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 121635478 Common pgpA phosphatidylglycerophosphatase A NMC1781 102 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 121635174 Common - hypothetical protein NMC1431 152 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121634715 Common - putative HlyD family secretion protein NMC0887 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121634486 Common trpF putative N-(5'-phosphoribosyl)anthranilate isomerase NMC0639 192 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 121634679 Pathogen - hypothetical protein NMC0845 1 None None None 121634676 Common - hypothetical protein NMC0842 3 COG4889 COG4889, Predicted helicase General function prediction only 121634698 Common - putative prophage-related protein NMC0865 24 COG5281 COG5281, Phage-related minor tail protein Function unknown 121634386 Common rimM 16S rRNA-processing protein NMC0533 186 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 121633929 Pathogen - hypothetical protein NMC0030 2 None None None 121633930 Common - hypothetical protein NMC0031 12 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 121635311 Common - hypothetical integral membrane protein NMC1588 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 121634424 Common - putative phosphate acyltransferase NMC0575 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 121634570 Common - hypothetical protein NMC0728 15 COG4390 COG4390, Uncharacterized protein conserved in bacteria Function unknown 121633947 Pathogen - hypothetical protein NMC0050 1 None None None 121635360 Common - hypothetical protein NMC1646 56 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 121635125 Common - hypothetical protein NMC1372 76 COG1556 COG1556, Uncharacterized conserved protein Function unknown 121634042 Common rpoA DNA-directed RNA polymerase subunit alpha NMC0158 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 121635431 Common ackA2 acetate kinase NMC1727 162 COG0282 ackA, Acetate kinase Energy production and conversion 121634312 Common - putative hemagglutinin NMC0452 7 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 121634112 Common - putative inner membrane protein NMC0236 29 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 121634275 Common pilO pilus assembly protein NMC0410 45 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 121634458 Common apaH diadenosine tetraphosphatase NMC0610 90 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 121634580 Common - hypothetical protein NMC0738 50 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 121634401 Common secD preprotein translocase subunit SecD NMC0550 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 121634841 Common - hypothetical protein NMC1035 88 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 121635594 Common atpF ATP synthase B chain NMC1910 77 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 121635656 Common - hypothetical inner membrane protein NMC1976 173 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 121635620 Common - putative ABC transport inner membrane subunit NMC1937 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 121634267 Common - putative lipopolysaccharide biosynthesis translocase NMC0402 10 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 121635709 Common petC cytochrome C1 precursor NMC2032 78 COG2857 CYT1, Cytochrome c1 Energy production and conversion 121634689 Pathogen - hypothetical protein NMC0856 1 None None None 121635483 Common hemN coproporphyrinogen III oxidase NMC1786 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 121634662 Common - hypothetical protein NMC0828 7 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 121635587 Common glyS glycyl-tRNA synthetase subunit beta NMC1903 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 121635438 Common - putative permease NMC1735 136 COG2252 COG2252, Permeases General function prediction only 121634621 Common pcnB putative poly(A) polymerase NMC0781 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 121635393 Common aspS aspartyl-tRNA synthetase NMC1684 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635543 Common emrB multidrug resistance translocase NMC1852 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121634659 Common sodB putative superoxide dismutase NMC0825 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 121635324 Common - dinucleoside polyphosphate hydrolase NMC1601 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121634874 Common fdx putative ferredoxin NMC1073 64 COG0633 Fdx, Ferredoxin Energy production and conversion 121635771 Pathogen - hypothetical protein NMC2099 1 None None None 121635238 Common hisD histidinol dehydrogenase NMC1501 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 121635721 Common slyX hypothetical protein NMC2044 8 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 121634669 Common - hypothetical protein NMC0835 76 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 121635467 Common - transcriptional regulator, arsr family NMC1769 56 COG4742 COG4742, Predicted transcriptional regulator Transcription 121635073 Common - hypothetical protein NMC1302 140 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 121635500 Pathogen - hypothetical protein NMC1804 1 None None None 121634088 Common pilE class II pilin PilE NMC0210 33 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121634344 Common - putative ABC transporter ATP-binding protein NMC0489 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121634583 Common - putative amino acid permease ATP-binding protein NMC0742 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121634862 Common - hypothetical protein NMC1059 8 None None None 121635077 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein NMC1306 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 121635815 Common - putative transmembrane transport protein NMC2150 97 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 121634474 Pathogen - hypothetical protein NMC0627 1 None None None 121634708 Pathogen - putative integral membrane protein NMC0878 1 None None None 121634465 Common - putative periplasmic protein NMC0618 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 121634079 Common aat leucyl/phenylalanyl-tRNA--protein transferase NMC0198 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 121634818 Common - putative sulphate-binding protein NMC1009 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 121635785 Common - putative integral membrane protein NMC2119 5 COG2259 COG2259, Predicted membrane protein Function unknown 121635763 Pathogen - hypothetical protein NMC2089 1 None None None 121634811 Common - hypothetical protein NMC1000 2 None None None 121634630 Common hisS histidyl-tRNA synthetase NMC0794 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121634533 Common - putative regulatory protein NMC0689 136 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 121634421 Common hisF imidazole glycerol phosphate synthase subunit HisF NMC0572 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 121634289 Common - putative transmembrane transport protein NMC0427 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 121635087 Common - HesB-like protein NMC1318 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 121634628 Common engA GTP-binding protein EngA NMC0792 227 COG1160 COG1160, Predicted GTPases General function prediction only 121634894 Common cysG sirohaem synthase NMC1096 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 121633999 Common - hypothetical protein NMC0113 5 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 121635455 Common mraW S-adenosyl-methyltransferase MraW NMC1755 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 121634536 Common rbgA ribosomal biogenesis GTPase NMC0692 106 COG1161 COG1161, Predicted GTPases General function prediction only 121634756 Common kgd alpha-ketoglutarate decarboxylase NMC0931 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 121635787 Common - hypothetical protein NMC2121 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 121634594 Common hemB delta-aminolevulinic acid dehydratase NMC0753 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 121634973 Common - putative dnaJ-family protein NMC1188 233 COG3671 COG3671, Predicted membrane protein Function unknown 121634632 Pathogen - hypothetical protein NMC0796 1 None None None 121634752 Common sdhA putative succinate dehydrogenase flavoprotein subunit NMC0927 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 121634809 Pathogen - hypothetical protein NMC0998 1 None None None 121634848 Pathogen - hypothetical protein NMC1042 1 None None None 121635170 Common - putative integral membrane protein (CstA-like) NMC1426 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 121635373 Common - hypothetical protein NMC1661 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 121635765 Common - hypothetical protein NMC2091 3 None None None 121635082 Common - putative type III restriction/modification system enzyme NMC1311 9 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 121635287 Common - putative sodium:alanine symporter NMC1562 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 121635290 Common - AsnC-family transcriptional regulator NMC1566 166 COG1522 Lrp, Transcriptional regulators Transcription 121635310 Common hemO haem utilisation protein NMC1587 12 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 121635443 Common murC UDP-N-acetylmuramate--L-alanine ligase NMC1741 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 121634924 Common lon putative ATP-dependent protease NMC1131 207 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 121634942 Common - putative two-component system sensor kinase NMC1150 142 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 121634823 Pathogen - hypothetical protein NMC1014 1 None None None 121634748 Common - putative redoxin NMC0923 106 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121635276 Common - hypothetical protein NMC1550 76 COG1262 COG1262, Uncharacterized conserved protein Function unknown 121634882 Pathogen - hypothetical protein NMC1083 1 None None None 121634031 Common rplF 50S ribosomal protein L6 NMC0147 235 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 121634437 Pathogen - putative lipoprotein NMC0588 1 None None None 121634332 Common - hypothetical protein NMC0476 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 121634052 Common lpxA UDP-N-acetylglucosamine acyltransferase NMC0168 154 COG1043 LpxA, Acyl- acyl carrier protein 121634292 Common - hypothetical protein NMC0430 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 121633906 Common - putative glycerate dehydrogenase NMC0006 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 121633922 Common - putative transposase NMC0022 74 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634331 Common - putative transmembrane transport protein NMC0475 57 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 121635498 Pathogen - putative lipoprotein NMC1802 1 None None None 121635278 Common - hypothetical protein NMC1552 74 COG0778 NfnB, Nitroreductase Energy production and conversion 121634999 Pathogen - hypothetical protein NMC1219 3 None None None 121635748 Common map methionine aminopeptidase NMC2073 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 121634705 Pathogen - putative integral membrane protein NMC0872 1 None None None 121635417 Pathogen - putative integral membrane protein NMC1712 1 None None None 121635396 Common - putative polyamine permease substrate-binding protein NMC1689 125 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121635204 Common - H.8 outer membrane protein NMC1462 19 COG3241 COG3241, Azurin Energy production and conversion 121635737 Pathogen - putative integral membrane protein NMC2060 1 None None None 121634558 Pathogen - putative integral membrane protein NMC0714 1 None None None 121634867 Common - putative periplasmic protein NMC1066 29 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 121634133 Common - ribosome-associated GTPase NMC0257 163 COG1162 COG1162, Predicted GTPases General function prediction only 121634764 Common uvrA excinuclease ABC subunit A NMC0941 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 121635549 Common - hypothetical protein NMC1858 12 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 121634022 Common rpsC 30S ribosomal protein S3 NMC0138 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 121635013 Common rpsA 30S ribosomal protein S1 NMC1238 222 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 121634116 Common nuoD NADH dehydrogenase subunit D NMC0240 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 121635184 Common - hypothetical protein NMC1442 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 121635531 Common pilG pilus-assembly protein NMC1838 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 121635603 Common - putative ABC transport ATP-binding subunit NMC1919 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 121634728 Common - putative acyl-CoA hydrolase NMC0902 131 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 121635730 Pathogen - putative periplasmic protein NMC2053 1 None None None 121635052 Common - hypothetical protein NMC1281 9 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 121634958 Common - putative P-type cation-transporting ATPase NMC1170 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 121634429 Common argH argininosuccinate lyase NMC0580 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 121635137 Common - impB/mucB/samB family protein NMC1386 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 121635666 Common - putative inner membrane protein NMC1986 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 121634337 Common - hypothetical protein NMC0481 21 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 121635212 Common fadD long-chain-fatty-acid--CoA-ligase NMC1472 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121635141 Common - putative inner membrane protein NMC1393 22 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 121634733 Common dapA dihydrodipicolinate synthase NMC0907 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 121635742 Common cybB putative cytochrome B561 NMC2066 12 COG3038 CybB, Cytochrome B561 Energy production and conversion 121634965 Pathogen - putative lipoprotein NMC1178 1 None None None 121635297 Pathogen - hypothetical protein NMC1573 1 None None None 121634982 Common - putative cation uptake regulator NMC1197 72 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 121635462 Common - hypothetical protein NMC1764 18 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 121634005 Common rplK 50S ribosomal protein L11 NMC0119 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 121634779 Common - hypothetical protein NMC0959 23 COG3686 COG3686, Predicted membrane protein Function unknown 121634992 Common - putative transmembrane transport protein NMC1208 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 121634453 Pathogen - hypothetical protein NMC0605 1 None None None 121635490 Common - hypothetical protein NMC1793 3 None None None 121634691 Common - putative phage-related protein NMC0858 28 None None None 121634949 Common - putative type I restriction enzyme system modification protein (pseudogene) NMC1158 8 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 121634178 Pathogen - hypothetical protein NMC0309 1 None None None 121635559 Pathogen - hypothetical protein NMC1870 1 None None None 121635545 Common - 7-cyano-7-deazaguanine reductase NMC1854 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 121635601 Common - putative lipoprotein NMC1917 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 121634139 Common - hypothetical protein NMC0263 169 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 121634413 Common - putative phosphatase NMC0563 149 COG0546 Gph, Predicted phosphatases General function prediction only 121634154 Pathogen - putative periplasmic protein NMC0280 1 None None None 121635337 Common - hypothetical protein NMC1615 2 None None None 121635643 Common - putative inner membrane protein NMC1960 3 COG5346 COG5346, Predicted membrane protein Function unknown 121634479 Pathogen - putative lipoprotein NMC0632 1 None None None 121635387 Common bioF 8-amino-7-oxononanoate synthase NMC1676 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 121634301 Common - Putative secretion protein NMC0439 21 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121634091 Common - putative inner membrane transport protein NMC0214 120 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121635210 Common - Remnant of transposase from insertion element IS1106A2 (Fragment) NMC1470 13 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634935 Pathogen - hypothetical protein NMC1143 1 None None None 121635638 Common - hypothetical protein NMC1955 6 COG4316 COG4316, Uncharacterized protein conserved in bacteria Function unknown 121634084 Common - putative inner membrane protein NMC0205 13 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 121634449 Common - hypothetical protein NMC0601 13 None None None 121635220 Common - putative gntR-family transcriptional regulator NMC1481 97 COG1802 GntR, Transcriptional regulators Transcription 121635710 Common petB cytochrome B NMC2033 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 121633961 Common lipB capsule polysaccharide modification protein NMC0067 31 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 121634399 Common - hypothetical protein NMC0548 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 121635421 Pathogen - putative integral membrane protein NMC1716 1 None None None 121635167 Common gabD succinate semialdehyde dehydrogenase NMC1423 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121634161 Common - hypothetical protein NMC0288 121 COG0557 VacB, Exoribonuclease R Transcription 121635799 Common - lipopolysaccharide heptosyltransferase I NMC2134 72 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 121635482 Common - putative anaerobic transcriptional regulatory protein NMC1785 153 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121634426 Common fbpB putative iron-uptake permease inner membrane protein NMC0577 204 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 121635706 Common - DNA ligase NMC2028 30 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 121634303 Pathogen - hypothetical protein NMC0441 1 None None None 121634990 Common - putative periplasmic protein NMC1205 17 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 121634947 Common - pseudogene (putative glycosyl transferase) NMC1156 206 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121634516 Common tgt queuine tRNA-ribosyltransferase NMC0671 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 121635061 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C NMC1290 122 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 121635252 Common - putative polyamine permease substrate-binding protein NMC1516 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121634785 Common - putative phage related protein NMC0965 15 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 121633980 Pathogen - putative inner membrane protein NMC0094 1 None None None 121633977 Pathogen - hypothetical protein NMC0089 1 None None None 121635654 Common purL phosphoribosylformylglycinamidine synthase NMC1972 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 121634249 Common ileS isoleucyl-tRNA synthetase NMC0383 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635233 Common ilvH acetolactate synthase isozyme III small subunit NMC1496 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 121634308 Common rte5 putative hemagglutinin/hemolysin-related protein NMC0448 4 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 121635358 Common - putative cytochrome oxidase subunit NMC1643 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 121634997 Common panD aspartate alpha-decarboxylase NMC1216 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 121634686 Common - hypothetical protein (putative ATP-binding protein) NMC0853 28 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 121634442 Common - hypothetical protein NMC0594 2 None None None 121635253 Common alaS alanyl-tRNA synthetase NMC1518 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121634194 Common leuS leucyl-tRNA synthetase NMC0326 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121634855 Pathogen - hypothetical protein NMC1051 1 None None None 121634258 Pathogen - hypothetical protein NMC0393 1 None None None 121635160 Common - phosphoglycolate phosphatase NMC1414 178 COG0546 Gph, Predicted phosphatases General function prediction only 121633945 Common rfbB dTDP-glucose 4,6-dehydratase NMC0047 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 121635148 Common - putative transglycosylase NMC1401 61 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121634054 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase NMC0170 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 121635359 Common - cytochrome c oxidase subunit NMC1645 143 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 121634563 Common pfs putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NMC0720 90 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 121635002 Common - putative iron-sulphur binding protein NMC1222 35 COG0633 Fdx, Ferredoxin Energy production and conversion 121635671 Common - insertion element IS1655 transposase NMC1993 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121635192 Common - putative transferase NMC1450 93 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 121635774 Common - hypothetical protein NMC2104 149 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 121633968 Pathogen - probable IS1016 transposase, partial CDS NMC0075 3 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634107 Common - hypothetical protein NMC0231 10 None None None 121634118 Common nuoF NADH dehydrogenase I chain F NMC0242 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 121634215 Common - hypothetical protein NMC0348 170 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 121635476 Common - putative integral membrane transport protein NMC1779 37 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 121634769 Pathogen - putative transposase (pseudogene) NMC0949 2 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635026 Common uraA uracil permease NMC1252 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 121634507 Common - hypothetical protein NMC0660 15 COG1714 COG1714, Predicted membrane protein/domain Function unknown 121635227 Common - conserved integral membrane hypothetical protein NMC1490 90 COG0795 COG0795, Predicted permeases General function prediction only 121635365 Common - hypothetical protein NMC1651 74 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 121635369 Common relA GTP pyrophosphokinase NMC1655 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 121635502 Pathogen - putative outer membrane hypothetical protein NMC1806 1 None None None 121634463 Common - hypothetical protein NMC0615 13 None None None 121634253 Common - putative TonB-dependent receptor NMC0387 110 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 121634183 Common - Maf-like protein NMC0314 179 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 121634566 Common - putative pilus biogenesis protein NMC0723 31 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 121635326 Common ldhA D-lactate dehydrogenase NMC1603 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 121635121 Common - putative lipoprotein NMC1367 143 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 121634548 Common - hypothetical protein NMC0704 205 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121634795 Common - putative transposase for IS1106 NMC0977 39 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121635283 Common infB translation initiation factor IF-2 NMC1557 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 121634741 Pathogen - putative lipoprotein NMC0916 1 None None None 121635123 Common - putative integral membrane protein NMC1370 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121634489 Common - hypothetical protein NMC0642 39 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 121634664 Common - hypothetical protein NMC0830 2 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 121634713 Pathogen - hypothetical protein NMC0883 1 None None None 121635172 Common lysC aspartate kinase NMC1429 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 121634098 Common - hypothetical protein NMC0222 7 COG4304 COG4304, Uncharacterized protein conserved in bacteria Function unknown 121634388 Common - hypothetical protein NMC0535 131 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 121634199 Common - hypothetical protein NMC0332 26 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 121634201 Common tpiA triosephosphate isomerase NMC0334 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 121634678 Pathogen - putative lipoprotein NMC0844 1 None None None 121635428 Common - hypothetical protein NMC1724 5 None None None 121634130 Common - putative inner membrane protei NMC0254 15 None None None 121635197 Common smpB SsrA-binding protein NMC1455 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 121633932 Common - putative inner membrane protein NMC0034 54 COG1289 COG1289, Predicted membrane protein Function unknown 121635246 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NMC1509 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 121634572 Common hemD uroporphyrinogen-III synthase NMC0730 40 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 121635128 Common - putative periplasmic protein NMC1375 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 121635313 Common - putative lipoprotein NMC1590 19 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 121634228 Common - putative lysR-family transcriptional regulator NMC0362 189 COG0583 LysR, Transcriptional regulator Transcription 121634120 Common nuoG NADH dehydrogenase subunit G NMC0244 190 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 121634456 Common - hypothetical protein NMC0608 2 None None None 121635723 Common - hemk protein NMC2046 220 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 121634915 Common - hypothetical protein NMC1122 3 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 121634155 Pathogen - putative inner membrane protein NMC0281 1 None None None 121635564 Pathogen - hypothetical protein NMC1875 1 None None None 121635528 Common fabI enoyl-(acyl carrier protein) reductase NMC1834 230 COG0623 FabI, Enoyl- acyl-carrier-protein 121635802 Common - glyceraldehyde 3-phosphate dehydrogenase C NMC2137 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 121635754 Pathogen - putative integral membrane protein NMC2079 1 None None None 121635758 Pathogen mafA adhesin NMC2083 1 None None None 121634003 Common secE preprotein translocase subunit SecE NMC0117 23 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 121634019 Common rplB 50S ribosomal protein L2 NMC0135 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 121634221 Common hemL glutamate-1-semialdehyde aminotransferase NMC0354 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 121634009 Common rpoB DNA-directed RNA polymerase subunit beta NMC0123 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 121635263 Pathogen - hypothetical protein NMC1531 1 None None None 121634209 Common - putative prolyl endopeptidase NMC0342 112 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 121635684 Common gntP putative gluconate permease NMC2006 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 121633902 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NMC0001 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 121635406 Common acpS holo-(acyl-carrier protein) synthase NMC1700 69 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 121634555 Common - hypothetical protein NMC0711 29 COG2836 COG2836, Uncharacterized conserved protein Function unknown 121634067 Common rnhB ribonuclease HII NMC0183 238 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 121634836 Common - putative integral membrane protein NMC1030 13 COG3235 COG3235, Predicted membrane protein Function unknown 121634241 Common - putative NADH:FMN oxidoreductase NMC0375 97 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 121634807 Common - conserved hypothetical protein (putative transcriptional regulator) NMC0995 7 COG1414 IclR, Transcriptional regulator Transcription 121634408 Common amtB putative ammonium transporter NMC0557 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 121635331 Common - putative phosphoglucomutase/phosphomannomutase NMC1608 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 121634599 Common ppnK inorganic polyphosphate/ATP-NAD kinase NMC0758 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 121634393 Common - hypothetical protein NMC0541 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 121635800 Common pncA putative nicotinamidase NMC2135 65 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 121634128 Common nuoM NADH dehydrogenase subunit M NMC0252 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 121634082 Common - putative inner membrane transport protein NMC0201 216 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 121634726 Common - putative C-type cytochrome NMC0900 25 COG3909 COG3909, Cytochrome c556 Energy production and conversion 121634311 Pathogen - hypothetical protein NMC0451 1 None None None 121633956 Common - putative transcriptional accessory protein NMC0059 178 COG2183 Tex, Transcriptional accessory protein Transcription 121635629 Pathogen hpuA haemoglobin-haptoglobin-utilization protein NMC1946 2 None None None 121635211 Common pyrG CTP synthetase NMC1471 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 121633912 Common - hypothetical protein NMC0012 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 121635536 Common - hypothetical protein NMC1845 28 COG2707 COG2707, Predicted membrane protein Function unknown 121635509 Common - putative outer membrane hypothetical protein NMC1813 69 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 121635609 Common - putative inner membrane protein NMC1926 19 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 121634605 Common hisZ ATP phosphoribosyltransferase regulatory subunit NMC0764 102 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 121634773 Pathogen - putative integral membrane protein NMC0953 1 None None None 121635111 Common - hypothetical protein NMC1354 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 121635663 Common - hypothetical inner membrane protein NMC1983 138 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 121635306 Common - hypothetical protein NMC1583 5 None None None 121634988 Common - putative polysaccharide modification protein NMC1203 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 121635532 Common pilD type IV prepilin leader peptidase NMC1839 143 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121635114 Pathogen - hypothetical protein NMC1358 1 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 121635044 Common - hypothetical lipoprotein NMC1273 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 121634826 Common glyA putative serine hydroxymethyltransferase NMC1017 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 121634950 Common - recombination factor protein RarA NMC1159 241 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 121634057 Common omp85 outer membrane protein OMP85 NMC0173 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 121634176 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III NMC0307 226 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 121634430 Common galU putative UTP--glucose-1-phosphate uridylyltransferase NMC0581 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 121633951 Common sacA N-acetylglucosamine-6-phosphate 2-epimerase NMC0054 51 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 121634663 Pathogen - hypothetical protein NMC0829 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 121635289 Common - putative disulphide bond formation protein NMC1564 37 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 121634333 Common - hypothetical protein NMC0477 200 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 121635780 Common - putative outer membrane protein NMC2112 121 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 121635585 Common lgtB lacto-N-neotetraose biosynthesis glycosyl tranferase NMC1901 14 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 121634074 Pathogen - hypothetical protein NMC0193 1 COG3792 COG3792, Uncharacterized protein conserved in bacteria Function unknown 121635010 Common - putative membrane bound murein transglycosylase NMC1234 134 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121634573 Common - hypothetical protein NMC0731 53 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 121635602 Common - putative inner membrane transport protein NMC1918 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 121634696 Common - hypothetical protein NMC0863 4 None None None 121634884 Common mpl putative UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase NMC1085 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 121634024 Common rpmC 50S ribosomal protein L29 NMC0140 143 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 121635041 Common uvrB excinuclease ABC subunit B NMC1269 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 121635735 Common - aspartate-semialdehyde dehydrogenase NMC2058 196 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 121635566 Pathogen opcB pseudogene (outer membrane protein) NMC1877 1 None None None 121635058 Pathogen - hypothetical protein NMC1287 1 None None None 121634033 Common rpsE 30S ribosomal protein S5 NMC0149 238 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 121634955 Common thrC threonine synthase NMC1165 161 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 121633994 Common smf SMF-family protein NMC0108 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 121634803 Common - hypothetical protein NMC0986 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 121635284 Common - putative integral membrane protein NMC1558 17 COG1161 COG1161, Predicted GTPases General function prediction only 121635152 Common - exopolyphosphatase NMC1405 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 121635383 Common - hypothetical protein NMC1672 2 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 121634135 Common ruvA Holliday junction DNA helicase motor protein NMC0259 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 121634865 Common - putative periplasmic protein NMC1063 22 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 121635635 Common lysA diaminopimelate decarboxylase NMC1952 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 121634934 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase NMC1142 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 121634626 Common - putative periplasmic protein NMC0790 3 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 121635740 Common - putative ATP-binding protein NMC2064 12 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 121634220 Common - hypothetical protein NMC0353 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 121634975 Common - hypothetical protein NMC1190 128 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 121635464 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase NMC1766 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 121634658 Common - putative integral membrane protein NMC0824 15 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 121635670 Common - modification methylase (cytosine-specific DNA methylase) NMC1992 108 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 121634683 Pathogen - hypothetical protein NMC0849 1 None None None 121634813 Common - hypothetical protein NMC1002 38 COG3926 zliS, Putative secretion activating protein General function prediction only 121634592 Common ftsJ putative cell division protein NMC0751 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 121635427 Common - hypothetical integral membrane protein NMC1722 53 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 121634638 Pathogen - hypothetical protein NMC0804 1 None None None 121635648 Common - putative inner membrane transport protein NMC1965 189 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 121635025 Common - ftsK-like cell division/stress response protein NMC1251 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 121635724 Common tldD TLDD protein homolog NMC2047 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 121635791 Common - insertion element IS1655 transposase NMC2125 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 121635432 Common - hypothetical protein NMC1728 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 121634786 Common - putative phage related protein NMC0966 6 None None None 121634262 Common pglC pilin glycosylation protein NMC0397 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 121634462 Common ligA putative DNA ligase NMC0614 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 121635089 Common gyrA DNA gyrase subunit A NMC1320 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 121634725 Common lst CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase NMC0899 6 None None None 121635655 Common - putative hydroxyacylglutathione hydrolase NMC1973 159 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121634422 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NMC0573 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 121635060 Common - hypothetical protein NMC1289 131 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 121634329 Common - hypothetical protein NMC0473 54 COG1238 COG1238, Predicted membrane protein Function unknown 121634193 Common mlp lipoprotein NMC0325 9 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 121634856 Pathogen - hypothetical protein NMC1052 1 None None None 121634011 Common rpsL 30S ribosomal protein S12 NMC0125 234 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 121634534 Common - HPr kinase/phosphorylase NMC0690 70 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 121634501 Common rluD putative ribosomal large subunit pseudouridine synthase D NMC0654 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121634362 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C NMC0508 47 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 121635703 Common ptsH sugar transport PTS system phosphocarrier protein HPR NMC2025 146 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 121634325 Common - beta-hexosaminidase NMC0469 172 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 121634490 Pathogen tpc putative tetrapac protein NMC0643 1 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 121634712 Common - Death-on-curing protein, prophage related protein NMC0882 15 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 121634504 Common - putative lipoprotein NMC0657 31 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 121635591 Common atpG F0F1 ATP synthase subunit gamma NMC1907 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 121634037 Common infA translation initiation factor IF-1 NMC0153 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 121635177 Common pncB nicotinate phosphoribosyltransferase NMC1435 92 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 121634285 Common metK S-adenosylmethionine synthetase NMC0422 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 121635445 Common ftsW cell division protein NMC1743 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 121635453 Common penA penicillin-binding protein 2 NMC1753 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 121634366 Common - hypothetical protein NMC0513 59 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 121634991 Common - acyl-CoA synthetase NMC1207 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121635550 Common - putative replication initiation factor NMC1861 12 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 121634963 Common gshA putative glutamate--cysteine ligase NMC1175 27 None None None 121635752 Common - hypothetical protein NMC2077 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 121635546 Common - hypothetical protein NMC1855 87 COG1738 COG1738, Uncharacterized conserved protein Function unknown 121634043 Common rplQ 50S ribosomal protein L17 NMC0159 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 121634891 Common cysN putative sulphate adenylate transferase subunit 1 NMC1093 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 121634274 Common pilP pilus assembly protein NMC0409 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 121635199 Common - putative methylated-DNA-protein-cysteine methyltransferase NMC1457 209 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 121634916 Pathogen - putative transposase (Fragment) NMC1123 1 None None None 121635414 Common - hypothetical protein NMC1709 12 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 121635593 Common atpH ATP synthase delta chain NMC1909 190 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 121635240 Common hisB imidazoleglycerol-phosphate dehydratase NMC1503 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 121634314 Pathogen - hypothetical protein NMC0454 1 None None None 121634582 Common - putative amino acid permease integral membrane protein NMC0741 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121634896 Common - hypothetical protein NMC1098 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 121635560 Common - conserved hypothetical inner membrane protein NMC1871 92 COG1981 COG1981, Predicted membrane protein Function unknown 121634872 Common - hypothetical protein NMC1071 2 None None None 121635573 Common - hypothetical protein NMC1886 12 COG1432 COG1432, Uncharacterized conserved protein Function unknown 121634346 Common priA primosome assembly protein PriA NMC0491 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 121634418 Common - hypothetical protein NMC0569 187 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 121635408 Pathogen - hypothetical protein NMC1702 1 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121634013 Common fusA elongation factor G NMC0127 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 121634243 Common - putative integral membrane protein NMC0377 44 COG2510 COG2510, Predicted membrane protein Function unknown 121634411 Common ppsA phosphoenolpyruvate synthase NMC0561 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 121635715 Common rplM 50S ribosomal protein L13 NMC2038 218 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 121635182 Common rpiA ribose-5-phosphate isomerase A NMC1440 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 121635701 Common - ABC-transport system ATP-binding protein NMC2023 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121634089 Common katA catalase NMC0211 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 121634834 Common - hypothetical protein NMC1028 168 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121635146 Common ssb single-stranded binding protein NMC1398 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 121634100 Common glnE putative glutamate-ammonia-ligase adenylyltransferase NMC0224 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 121635318 Common - putative cytochrome NMC1595 44 COG3245 CycB, Cytochrome c5 Energy production and conversion 121633937 Common proC putative pyrroline-5-carboxylate reductase NMC0039 211 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 121633917 Common tbpA putative solute-binding periplasmic protein NMC0017 75 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 121635576 Common - conserved hypothetical inner membrane protein NMC1890 25 COG2259 COG2259, Predicted membrane protein Function unknown 121634576 Common radA DNA repair protein RadA NMC0734 206 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 121634777 Common - hypothetical protein NMC0957 45 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 121634617 Common - hypothetical protein NMC0777 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 121634390 Common - putative two-component system regulator NMC0537 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121634645 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase NMC0811 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 121634223 Common prmA ribosomal protein L11 methyltransferase NMC0356 184 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 121635107 Common - hypothetical protein NMC1348 30 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 121634156 Pathogen - hypothetical protein (doubtful) NMC0282 1 None None None 121633966 Common - putative outer membrane transport protein NMC0073 70 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 121634797 Common - putative rubredoxin NMC0980 122 COG1773 COG1773, Rubredoxin Energy production and conversion 121635562 Common folA dihydrofolate reductase NMC1873 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 121634188 Pathogen rpmH 50S ribosomal protein L34 NMC0319 2 None None None 121634095 Common pyrD dihydroorotate dehydrogenase 2 NMC0218 237 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 121634906 Common - hypothetical protein NMC1112 55 COG2921 COG2921, Uncharacterized conserved protein Function unknown 121634523 Common nmeDIMP putative modification methylase NmeDI NMC0679 84 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 121633924 Pathogen - putative inner membrane protein NMC0024 1 None None None 121635641 Common - hypothetical protein NMC1958 11 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121634759 Pathogen - hypothetical protein NMC0934 1 None None None 121634123 Common nuoJ NADH dehydrogenase I chain J NMC0247 58 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 121634854 Pathogen - hypothetical protein NMC1050 1 None None None 121634743 Common metX homoserine O-acetyltransferase NMC0918 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 121635169 Pathogen - putative lipoprotein NMC1425 2 None None None 121635511 Common - hypothetical protein NMC1815 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 121635726 Common - putative oxidoreductase NMC2049 56 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121634559 Common cysK putative cysteine synthase NMC0715 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 121635772 Pathogen - hypothetical protein NMC2100 1 None None None 121634405 Common - putative polyamine permease inner membrane protein NMC0554 205 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 121635038 Common - hypothetical protein NMC1265 92 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 121634653 Common ilvA threonine dehydratase NMC0819 210 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 121635401 Common amiC N-acetylmuramoyl-L-alanine amidase NMC1694 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 121635094 Common glk glucokinase NMC1329 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 121635304 Common - hypothetical protein NMC1581 117 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 121633933 Common pilU PilT-like protein NMC0035 205 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 121635260 Common - putative two component response regulator NMC1527 213 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121634203 Common - putative protein-L-isoaspartate O-methyltransferase NMC0336 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 121635430 Common - hypothetical protein NMC1726 226 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 121633943 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase NMC0045 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 121635126 Common - conserved hypothetical iron-sulphur protein NMC1373 98 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 121635221 Common - hypothetical protein NMC1483 88 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121634420 Common hisI putative phosphoribosyl-AMP cyclohydrolase NMC0571 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 121635206 Common dnaG DNA primase NMC1465 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 121635779 Common - putative symport protein NMC2110 151 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 121634495 Common ksgA dimethyladenosine transferase NMC0648 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 121634197 Pathogen - hypothetical protein NMC0329 1 None None None 121635518 Common - hypothetical protein NMC1824 32 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121634062 Common frr ribosome recycling factor NMC0178 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 121634918 Common - putative periplasmic protein NMC1125 3 None None None 121635011 Common - putative ribosomal small subunit pseudouridine synthase NMC1235 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121634452 Common - hypothetical protein NMC0604 2 None None None 121634706 Pathogen - hypothetical protein NMC0873 1 None None None 121634218 Common xerC putative integrase/recombinase NMC0351 228 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 121635356 Common recC exodeoxyribonuclease V NMC1638 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 121635004 Common - hypothetical protein NMC1225 35 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 121635353 Common mtrR transcriptional regulato NMC1635 125 COG1309 AcrR, Transcriptional regulator Transcription 121633992 Common - putative two-component sensor kinase NMC0106 220 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 121634775 Pathogen - hypothetical protein NMC0955 1 None None None 121635300 Common spoT guanosine-3',5'-bis(diphosphate) 3'-pyrophophohydrolase NMC1577 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 121634513 Pathogen - hypothetical protein NMC0667 1 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 121634514 Common - putative cytochrome C NMC0668 49 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 121635363 Common exbB biopolymer transport protein NMC1649 151 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 121635056 Common - hypothetical protein NMC1285 6 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 121635231 Common ilvC ketol-acid reductoisomerase NMC1494 211 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 121634230 Common - hypothetical protein NMC0364 8 None None None 121635661 Common - hypothetical inner membrane protein NMC1981 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 121634561 Common lepB putative signal peptidase I NMC0718 204 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 121634749 Common lpdA2 dihydrolipoamide dehydrogenase NMC0924 236 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121634755 Common gltA type II citrate synthase NMC0930 194 COG0372 GltA, Citrate synthase Energy production and conversion 121635251 Common - hypothetical protein NMC1515 84 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121635261 Common - hypothetical protein NMC1528 50 None None None 121635139 Common - putative DNA polymerase III subunit NMC1391 189 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 121635321 Common aroC chorismate synthase NMC1598 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 121634109 Common - hypothetical protein NMC0233 8 None None None 121634904 Common lipA lipoyl synthase NMC1110 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 121634065 Common gidB glucose-inhibited division protein B NMC0181 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 121633974 Common - putative protein export protein NMC0085 112 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121634926 Common recD exodeoxyribonuclease V alpha subunit NMC1133 126 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 121635218 Common glpR glycerol 3-phosphate regulon repressor NMC1479 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 121634217 Common fba fructose-1,6-bisphosphate aldolase NMC0350 175 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 121634026 Common rplN 50S ribosomal protein L14 NMC0142 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 121634688 Pathogen - hypothetical protein NMC0855 3 None None None 121635029 Common pss phosphatidylserine synthase NMC1255 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 121634078 Common fur ferric uptake regulation protein NMC0197 200 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 121635809 Common - Putative periplasmic thiredoxin NMC2144 88 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121635371 Common - putative periplasmic type I secretion system protein NMC1658 115 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121635708 Common - putative periplasmic protein NMC2030 181 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 121635381 Common - hypothetical protein NMC1670 2 None None None 121635020 Common - hypothetical protein NMC1245 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 121634518 Common infC translation initiation factor IF-3 NMC0673 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 121635685 Common - putative glucokinase NMC2007 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 121635348 Common - GntR-family transcriptional regulator NMC1629 128 COG2186 FadR, Transcriptional regulators Transcription 121634144 Common trpC indole-3-glycerol phosphate synthase NMC0270 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 121634801 Common dld D-lactate dehydrogenase NMC0984 72 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121635296 Pathogen - hypothetical protein NMC1572 1 None None None 121634185 Common - putative inner membrane protein translocase component YidC NMC0316 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 121634546 Common hfq putative regulator NMC0702 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 121634096 Pathogen - hypothetical protein NMC0220 1 None None None 121634358 Common apbE putative thiamine biosynthesis protein NMC0504 139 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 121635468 Common nadC nicotinate-nucleotide pyrophosphorylase NMC1770 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 121635676 Common coaD phosphopantetheine adenylyltransferase NMC1998 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 121634349 Common dnaK putative chaperone protein NMC0495 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121634167 Common - putative DNA methylase NMC0295 94 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 121633997 Pathogen - hypothetical protein NMC0111 1 None None None 121634610 Common rfaE putative DP-heptose synthetase NMC0769 141 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 121635370 Common natC putative periplasmic type I secretion system protein NMC1657 106 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121635486 Pathogen mafA2 adhesin MafA2 NMC1789 1 None None None 121635473 Common pgm2 beta-phosphoglucomutase NMC1776 134 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 121634352 Common - hypothetical protein NMC0498 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 121634114 Common nuoB NADH dehydrogenase subunit B NMC0238 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 121634163 Common purB adenylosuccinate lyase NMC0290 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 121634781 Common serB putative phosphoserine phosphatase NMC0961 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 121635818 Common gnd 6-phosphogluconate dehydrogenase NMC2153 181 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 121635689 Common - LgtG NMC2011 77 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121634526 Common himA putative integration host factor alpha-subunit NMC0682 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 121634824 Common abcZ putative ABC transporter ATP-binding protein NMC1015 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121634941 Common - putative molybdopterin-guanine dinucleotide biosynthesis protein A NMC1149 61 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 121634432 Pathogen - hypothetical protein NMC0583 1 None None None 121635095 Common pgl 6-phosphogluconolactonase NMC1330 122 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 121635294 Common - putative periplasmic protein NMC1570 20 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 121635494 Common - hypothetical protein NMC1798 4 None None None 121635633 Common - Insertion element IS1016 transposase NMC1950 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634335 Common aspC aromatic amino acid aminotransferase NMC0479 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121635552 Pathogen - hypothetical protein NMC1863 1 None None None 121634439 Pathogen - hypothetical protein NMC0591 1 None None None 121634840 Common leuA 2-isopropylmalate synthase NMC1034 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 121634146 Common - putative inner membrane protein NMC0272 194 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 121633986 Pathogen - putative inner membrane protein NMC0100 1 None None None 121634485 Common era GTP-binding protein Era NMC0638 216 COG1159 Era, GTPase General function prediction only 121635718 Common gpsA glycerol-3-phosphate dehydrogenase NMC2041 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 121634473 Pathogen - hypothetical protein NMC0626 1 None None None 121635189 Common ackA1 acetate kinase NMC1447 162 COG0282 ackA, Acetate kinase Energy production and conversion 121634972 Common - putative integral membrane protein NMC1186 15 None None None 121635733 Common folD methylenetetrahydrofolate dehydrogenase/cyclohydrolase NMC2056 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 121635782 Common - putative peptide transporter NMC2114 77 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 121634416 Common - putative polyamine permease substrate-binding protein NMC0567 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121634702 Common - putative phage-related protein NMC0869 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 121634375 Common - putative lipoprotein NMC0522 27 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 121634920 Common - hypothetical protein NMC1127 11 COG3737 COG3737, Uncharacterized conserved protein Function unknown 161723297 Common - YciI-like protein NMC1827 70 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 121634137 Common - putative periplasmic protein NMC0261 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 121634701 Common - putative phage-related protein NLPC_P60 NMC0868 13 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 121634783 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NMC0963 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 121634656 Common cysU putative sulphate permease inner membrane protein NMC0822 230 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 121634319 Common rbn ribonuclease BN/unknown domain fusion protein NMC0462 75 COG1295 Rbn, Predicted membrane protein Function unknown 121634150 Common - putative rotamase NMC0276 162 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121635507 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase NMC1811 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 121634395 Common - putative sec-independent protein translocase component NMC0543 83 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 121633909 Pathogen - putative lipoprotein NMC0009 1 None None None 121634191 Common ppk polyphosphate kinase NMC0323 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 121634080 Common gapA glyceraldehyde 3-phosphate dehydrogenase NMC0199 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 121635749 Common - hypothetical protein NMC2074 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 121634237 Common pilC1 pilus-associated protein NMC0371 27 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 121634737 Common - putative cytosine deaminase NMC0911 221 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 121634279 Common - GTPase EngB NMC0415 184 COG0218 COG0218, Predicted GTPase General function prediction only 121634035 Common rplO 50S ribosomal protein L15 NMC0151 197 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 121634881 Pathogen - putative lipoprotein NMC1082 1 None None None 121634928 Common - putative integral membrane protein NMC1135 214 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 121635538 Common rplU 50S ribosomal protein L21 NMC1847 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 121635157 Common - putative tautomerase NMC1411 32 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 121634770 Common - putative phage replication initiation protein NMC0950 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 121634986 Common - hypothetical protein NMC1201 34 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 121635746 Common - putative lipoprotein NMC2071 53 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 121635180 Common - putative binding-protein-dependent transport systems inner membrane protein NMC1438 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121634961 Common - hypothetical protein NMC1173 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 121633914 Common phnA putative phosphonoacetate hydrolase NMC0014 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 121635333 Common - hypothetical protein NMC1610 40 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 121634369 Common gcvT glycine cleavage system aminomethyltransferase T NMC0516 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 121634828 Pathogen - hypothetical protein NMC1020 1 None None None 121635534 Common - hypothetical protein NMC1842 61 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 121635346 Common gdhA glutamate dehydrogenase NMC1625 174 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 121635807 Common - putative periplasmic protein NMC2142 55 COG1434 COG1434, Uncharacterized conserved protein Function unknown 121635113 Common - hypothetical protein NMC1357 100 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121634059 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase NMC0175 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 121634283 Common gcp O-sialoglycoprotein endopeptidase NMC0419 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 121635451 Common - pseudogene (putative integral membrane protein) NMC1750 51 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 121634665 Common - putative pilin NMC0831 65 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 121634845 Common - hypothetical protein NMC1039 73 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 121634327 Common - putative periplasmic serine protease NMC0471 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 121634718 Pathogen - putative integral membrane protein NMC0890 1 None None None 121634046 Common minE putative cell division topological specificity factor NMC0162 82 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 121635487 Common - adhesin MafB2 NMC1790 14 None None None 121634640 Pathogen - putative integral membrane protein NMC0806 1 None None None 121635575 Common - hypothetical protein NMC1889 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 121635175 Common - hypothetical protein NMC1432 170 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 121635568 Common - putative DNA transport competence protein NMC1880 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 121634898 Common vacB putative ribonuclease NMC1102 196 COG0557 VacB, Exoribonuclease R Transcription 121634651 Common - 50S ribosomal protein L25/general stress protein Ctc NMC0817 195 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 121634000 Common - hypothetical protein NMC0114 210 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 121634649 Common - hypothetical protein NMC0815 190 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 121633979 Common - putative periplasmic peptidase (bacteriocin resistance) NMC0093 45 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 121634368 Common - putative AsnC-family transcriptional regulator NMC0515 166 COG1522 Lrp, Transcriptional regulators Transcription 121635132 Common - hypothetical protein NMC1380 186 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 121634886 Pathogen - hypothetical protein NMC1088 1 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 121634525 Common pheT phenylalanyl-tRNA synthetase subunit beta NMC0681 245 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 121635270 Common rnhA ribonuclease HI NMC1544 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 121634711 Common - hypothetical protein NMC0881 3 None None None 121634587 Common - hypothetical protein NMC0746 2 COG5652 COG5652, Predicted integral membrane protein Function unknown 121635598 Pathogen - hypothetical protein NMC1914 2 None None None 121635150 Common opaA pseudogene (opacity protein) NMC1403 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121634295 Common recG putative DNA helicase NMC0433 212 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 121635711 Common petA ubiquinol-cytochrome c reductase iron-sulfur subunit NMC2034 92 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 121634893 Common cysH phosphoadenosine phosphosulfate reductase NMC1095 162 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 121635653 Common glnB nitrogen regulatory protein P-II 1 NMC1971 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 121634364 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A NMC0510 43 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 121634584 Common pgm phosphoglucomutase NMC0743 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 121634039 Common rpsM 30S ribosomal protein S13 NMC0155 238 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 121635190 Common dipZ thiol:disulfide interchange protein precursor NMC1448 111 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121634671 Common - hypothetical protein NMC0837 6 COG3692 COG3692, Uncharacterized protein conserved in bacteria Function unknown 121634608 Common adk adenylate kinase NMC0767 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 121635017 Common esd esterase D NMC1242 96 COG0627 COG0627, Predicted esterase General function prediction only 121635116 Common - putative integral membrane protein NMC1362 24 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 121634323 Common - hypothetical protein NMC0467 23 COG3759 COG3759, Predicted membrane protein Function unknown 121634870 Common - putative poly-isoprenyl transferase NMC1069 113 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 121635412 Common - putative integral membrane efflux protein NMC1706 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121635208 Common lbpA lactoferrin binding protein A NMC1468 61 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121634953 Common - putative integral membrane protein NMC1163 9 None None None 121634041 Common rpsD 30S ribosomal protein S4 NMC0157 216 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 121635397 Common tbpA transferrin-binding protein A NMC1690 74 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121634348 Common - putative transposase NMC0494 54 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635627 Common - putative para-aminobenzoate synthase component I NMC1944 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 121633954 Common ctrC capsule polysaccharide export inner-membrane protein NMC0057 68 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 121634636 Pathogen - hypothetical protein NMC0802 1 None None None 121634681 Common - hypothetical protein NMC0847 3 None None None 121634060 Common cdsA phosphatidate cytidylyltransferase NMC0176 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 121635760 Pathogen - hypothetical protein NMC2085 1 None None None 121634590 Common - hypothetical protein NMC0749 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 121634723 Common - Putative transposase for IS1106A3 (fragment) NMC0896 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 121634603 Common murB putative UDP-N-acetylenolpyruvoylglucosamine reductase NMC0762 192 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 121634751 Common sdhD putative succinate dehydrogenase hydrophobic membrane anchor protein NMC0926 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 121635083 Common lldA L-lactate dehydrogenase NMC1312 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 121635201 Common dapE succinyl-diaminopimelate desuccinylase NMC1459 215 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 121634932 Common - hypothetical protein NMC1139 105 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 121633941 Common dnaJ DnaJ protein NMC0043 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 121635099 Common mutY adenine glycosylase NMC1336 230 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 121635023 Common clpP endopeptidase NMC1248 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121634839 Common proB gamma-glutamyl kinase NMC1033 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 121634993 Common gcr site-specific recombinase NMC1210 23 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 121635241 Common - hypothetical protein NMC1504 174 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 121635308 Common - hypothetical protein NMC1585 10 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 121635459 Common - putative thiol:disulphide interchange protein NMC1760 66 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121634271 Common aroB 3-dehydroquinate synthase NMC0406 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 121635066 Common pdxH pyridoxamine 5'-phosphate oxidase NMC1295 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 121635770 Pathogen - hypothetical protein NMC2097 1 None None None 121635777 Pathogen - putative integral membrane protein NMC2108 1 None None None 121634863 Pathogen - hypothetical protein NMC1060 2 None None None 121634480 Common pyrC dihydroorotase NMC0633 99 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 121634550 Common - putative ferredoxin NMC0706 21 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 121634254 Common - putative esterase NMC0388 40 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 121634930 Common recR putative recombination protein NMC1137 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 121634852 Common - putative phage transposase NMC1048 28 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 121634492 Pathogen folI putative transcriptional regulator NMC0645 1 None None None 121634502 Common - putative transmembrane transport protein NMC0655 75 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 121635280 Common serC phosphoserine aminotransferase NMC1554 111 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 121635214 Common - hypothetical protein NMC1474 77 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 121634350 Pathogen - hypothetical protein NMC0496 1 None None None 121635124 Common - hypothetical protein NMC1371 151 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 121634528 Pathogen fxsA FxsA NMC0684 2 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 121634760 Common sucC succinyl-CoA synthetase subunit beta NMC0935 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 121633935 Common - hypothetical protein NMC0037 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 121635299 Common - hypothetical protein NMC1576 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 121634790 Pathogen - putative phage related protein NMC0971 1 None None None 121634205 Common - putative ferric siderophore receptor protein NMC0338 94 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 121634125 Common - hypothetical protein NMC0249 30 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 121635064 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B NMC1293 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 121634699 Common - putative phage-related protein NMC0866 11 COG4718 COG4718, Phage-related protein Function unknown 121635285 Common - putative integral membrane protein NMC1559 9 None None None 121634195 Common - putative DNA adenine methylase NMC0327 95 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 121634552 Common rfbD putative dTDP-4-dehydrorhamnose reductase NMC0708 169 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 121635608 Common regF putative regulator of pilE expression NMC1925 109 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121635330 Common - DedA-family integral membrane protein NMC1607 145 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 121634545 Common - hypothetical protein NMC0701 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121635764 Pathogen - mafb protein (fragment) NMC2090 1 None None None 121634497 Common trpB tryptophan synthase subunit beta NMC0650 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 121635033 Common priB primosomal replication protein NMC1259 15 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 121634287 Common - putative peptidase NMC0425 106 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 121634832 Common - putative integral membrane protein NMC1026 153 COG0344 COG0344, Predicted membrane protein Function unknown 121634225 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit NMC0358 198 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 121635402 Common - hypothetical protein NMC1695 32 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121634159 Common - hypothetical protein NMC0285 9 COG4128 Zot, Zonula occludens toxin General function prediction only 121633919 Common - hypothetical protein NMC0019 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 121634102 Common - putative inner membrane transport protein NMC0226 24 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 121635578 Common phr deoxyribodopyrimidine photolyase NMC1892 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 121634007 Common rplJ 50S ribosomal protein L10 NMC0121 210 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 121634381 Common - putative periplasmic binding protein NMC0528 166 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 121634015 Common rpsJ 30S ribosomal protein S10 NMC0129 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 121635525 Common - hypothetical protein NMC1831 59 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 121635728 Common - hypothetical protein NMC2051 15 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 121635036 Common - putative cation-transporting ATPase NMC1262 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 121635447 Common - putative periplasmic protein NMC1746 5 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 121635343 Common - putative integral membrane ion transporter NMC1622 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 121635750 Common - putative adhesin component NMC2075 3 None None None 121634860 Common - hypothetical protein NMC1057 17 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 121634392 Common - hypothetical protein NMC0540 13 COG3308 COG3308, Predicted membrane protein Function unknown 121634298 Common - hypothetical protein NMC0436 25 COG2850 COG2850, Uncharacterized conserved protein Function unknown 121634673 Common - consered hypothetical protein NMC0839 3 None None None 121634093 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II NMC0216 211 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121634716 Common - putative ABC transporter NMC0888 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 121635109 Common ruvC Holliday junction resolvase NMC1352 191 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 121635713 Common metR putative transcriptional activator protein METR NMC2036 189 COG0583 LysR, Transcriptional regulator Transcription 121635267 Common trkA potassium transporter peripheral membrane component NMC1535 139 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 121634530 Common bioD dithiobiotin synthetase NMC0686 155 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 121635762 Pathogen - hypothetical protein NMC2088 2 None None None 121634132 Common xseB exodeoxyribonuclease small subunit NMC0256 72 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 121635159 Common - putative glutamate dehydrogenase NMC1413 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 121635687 Common ubiG 3-demethylubiquinone-9 3-methyltransferase NMC2009 172 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 121635588 Common glyQ glycyl-tRNA synthetase subunit alpha NMC1904 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 121635479 Common thiL thiamine monophosphate kinase NMC1782 195 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 121634239 Common - putative periplasmic thioredoxin NMC0373 24 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121634169 Pathogen - hypothetical protein NMC0298 1 None None None 121634245 Common - translation-associated GTPase NMC0379 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 121634160 Common - putative invertase/transposase NMC0286 74 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121634317 Pathogen - putative integral membrane protein NMC0458 1 None None None 121634943 Common - putative two-component system response regulator NMC1151 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121634788 Pathogen - putative phage related protein NMC0969 1 None None None 121633907 Common metG methionyl-tRNA synthetase NMC0007 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121635258 Common parC DNA topoisomerase IV subunit A NMC1525 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 121635613 Common - putative periplasmic protein NMC1930 165 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121634983 Common - putative protein-tyrosine-phosphatase NMC1198 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 121635583 Common lgtB2 lacto-N-neotetraose biosynthesis glycosyl tranferase NMC1900 14 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 121634612 Common nmgI putative type II restriction endonuclease NMC0772 25 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 121634441 Common - hypothetical protein NMC0593 3 None None None 121633939 Common - putative DNA transport competence protein NMC0041 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 121634911 Common - hypothetical protein NMC1117 20 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 121634165 Common dinG ATP-dependent DNA helicase DinG NMC0293 130 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 121635811 Common ftsX putative ABC transporter integral membrane protein NMC2146 109 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 121634444 Pathogen - Adhesin MafA2 NMC0596 1 None None None 121633972 Pathogen - hypothetical protein NMC0083A 1 None None None 121633964 Common - putative lipoprotein NMC0071 2 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 121634355 Common cysE putative serine acetyltransferase NMC0501 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 121635471 Common nadB L-aspartate oxidase NMC1773 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 121635391 Common speA arginine decarboxylase NMC1682 103 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 121634304 Common - putative hemolysin activator NMC0443 42 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 121635696 Common - hypothetical protein NMC2018 3 COG2336 MazE, Growth regulator Signal transduction mechanisms 121634260 Common avtA valine--pyruvate transaminase NMC0395 191 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 121633988 Common def peptide deformylase NMC0102 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 121635492 Pathogen - hypothetical protein NMC1796 2 None None None 121635793 Common - hypothetical protein NMC2128 175 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 121635223 Common purN phosphoribosylglycinamide transformylase NMC1486 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 121634173 Common - putative ABC transporter ATP-binding protein NMC0304 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 121635789 Common - RNA polymerase sigma factor NMC2123 145 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121634511 Common - hypothetical protein NMC0665 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 121635658 Common - hypothetical outer membrane protein NMC1978 140 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 121634799 Common - hypothetical protein NMC0982 64 COG2128 COG2128, Uncharacterized conserved protein Function unknown 121635425 Common - hypothetical protein NMC1720 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 121635660 Common - hypothetical inner membrane protein NMC1980 46 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 121635541 Common rpmG 50S ribosomal protein L33 NMC1850 140 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 121635731 Common birA bifunctional biotin--[acetyl-CoA-carboxylase] ligase/pantothenate kinase NMC2054 217 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 121635104 Common - Insertion element IS1016 transposase NMC1343 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 121635226 Common pepA aminopeptidase A NMC1489 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 121634970 Common - putative periplasmic protein NMC1183 111 COG2353 COG2353, Uncharacterized conserved protein Function unknown 121635216 Common gshB glutathione synthetase NMC1477 132 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 121635361 Common - hypothetical protein NMC1647 41 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 121634619 Pathogen - hypothetical protein NMC0779 1 None None None 121634028 Common rplE 50S ribosomal protein L5 NMC0144 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 121635377 Pathogen - putative integral membrane protein NMC1665 1 None None None 121634902 Common bfrB putative bacterioferritin B NMC1107 98 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 121635162 Common - putative acyl-CoA hydrolase NMC1417 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 121635769 Common - hypothetical protein NMC2096 4 None None None 121634021 Common rplV 50S ribosomal protein L22 NMC0137 224 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 121635646 Common fetA putative iron-regulated outer membrane protein NMC1963 43 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121635516 Common - tRNA-dihydrouridine synthase A NMC1822 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 121634667 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase NMC0833 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism