Mycobacterium sp. KMS plasmid pMKMS01, complete sequence NC_008703 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 119855033 Common - L-carnitine dehydratase/bile acid-inducible protein F Mkms_5642 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 119854966 Common - Integrase, catalytic region Mkms_5572 62 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855020 Common - Alcohol dehydrogenase GroES domain protein Mkms_5628 214 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 119854952 Common - protein kinase Mkms_5558 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 119854984 Common - Integrase, catalytic region Mkms_5591 51 None None None 119855057 Common - transcriptional repressor, CopY family Mkms_5668 32 COG3682 COG3682, Predicted transcriptional regulator Transcription 119854944 Nonpathogen - hypothetical protein Mkms_5550 3 None None None 119854890 Nonpathogen - hypothetical protein Mkms_5495 1 None None None 119855030 Common - transcriptional regulator, MarR family Mkms_5638 2 COG1846 MarR, Transcriptional regulators Transcription 119855013 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mkms_5621 28 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119855007 Common - class II aldolase/adducin family protein Mkms_5614 7 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 119855145 Common - hypothetical protein Mkms_5759 1 None None None 119855158 Nonpathogen - PE_2 Mkms_5773 1 None None None 119854907 Nonpathogen - hypothetical protein Mkms_5512 1 None None None 119855082 Common - hypothetical protein Mkms_5694 17 None None None 119855040 Nonpathogen - Cupin 2, conserved barrel domain protein Mkms_5649 2 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 119855049 Common - copper resistance protein CopC Mkms_5659 52 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 119855072 Common - protein of unknown function DUF305 Mkms_5683 36 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 119855009 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mkms_5616 33 None None None 119854930 Common - Glutaredoxin-like protein NrdH Mkms_5535 31 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 119854976 Nonpathogen - hypothetical protein Mkms_5583 2 None None None 119854939 Common - membrane protein, MmpL family Mkms_5544 33 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 119854918 Common - helix-turn-helix domain protein Mkms_5523 18 None None None 119855155 Nonpathogen - putative methyl-accepting chemotaxis sensory transducer Mkms_5770 1 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 119855118 Nonpathogen - hypothetical protein Mkms_5731 3 None None None 119855111 Nonpathogen - hypothetical protein Mkms_5724 3 None None None 119855061 Common - cytochrome c assembly protein Mkms_5672 160 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 119855054 Common - hypothetical protein Mkms_5665 19 COG3336 COG3336, Predicted membrane protein Function unknown 119855099 Common - hypothetical protein Mkms_5711 39 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 119855161 Nonpathogen - hypothetical protein Mkms_5776 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 119854982 Common - hypothetical protein Mkms_5589 10 COG3953 COG3953, SLT domain proteins General function prediction only 119855002 Common - alpha/beta hydrolase fold Mkms_5609 160 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119854946 Common - phage integrase family protein Mkms_5552 197 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119855039 Common - 3-phenylpropionate dioxygenase subunit beta Mkms_5648 25 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119855138 Common - protein of unknown function DUF81 Mkms_5752 17 COG0730 COG0730, Predicted permeases General function prediction only 119854998 Common - hypothetical protein Mkms_5605 20 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 119855017 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mkms_5625 29 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119855000 Common - transposase IS3/IS911 family protein Mkms_5607 59 None None None 119855015 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Mkms_5623 19 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 119855143 Nonpathogen - hypothetical protein Mkms_5757 6 None None None 119854961 Nonpathogen - hypothetical protein Mkms_5567 1 None None None 119855125 Common - hypothetical protein Mkms_5738 26 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 119855084 Common - copper-translocating P-type ATPase Mkms_5696 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119854892 Nonpathogen - hypothetical protein Mkms_5497 1 None None None 119854954 Nonpathogen - hypothetical protein Mkms_5560 1 None None None 119855168 Common - hypothetical protein Mkms_5783 5 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 119854920 Nonpathogen - hypothetical protein Mkms_5525 1 None None None 119854902 Common - type III restriction enzyme, res subunit Mkms_5507 21 COG4889 COG4889, Predicted helicase General function prediction only 119855047 Common - putative conserved lipoprotein LpqU Mkms_5657 27 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 119854905 Common - FHA domain containing protein Mkms_5510 1 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 119855105 Common - hypothetical protein Mkms_5718 14 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 119855149 Common - hypothetical protein Mkms_5764 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 119854978 Nonpathogen - hypothetical protein Mkms_5585 1 None None None 119855142 Common - hypothetical protein Mkms_5756 16 None None None 119855097 Common - putative ABC transporter membrane protein Mkms_5709 4 None None None 119855052 Nonpathogen - hypothetical protein Mkms_5663 1 None None None 119855079 Common - hypothetical protein Mkms_5691 55 COG3000 ERG3, Sterol desaturase Lipid metabolism 119855131 Common - cadmium resistance transporter Mkms_5745 16 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 119854996 Common - hypothetical protein Mkms_5603 10 None None None 119855115 Nonpathogen - hypothetical protein Mkms_5728 4 None None None 119854923 Nonpathogen - hypothetical protein Mkms_5528 1 None None None 119854951 Common - DNA ligase (ATP) Mkms_5557 105 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 119854991 Common - hypothetical protein Mkms_5598 1 None None None 119855124 Common - putative adenylate/guanylate cyclase Mkms_5737 36 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 119854898 Common - AAA ATPase, central domain protein Mkms_5503 57 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 119854940 Common - hypothetical protein Mkms_5545 33 None None None 119854969 Nonpathogen - hypothetical protein Mkms_5576 1 None None None 119854956 Nonpathogen - hypothetical protein Mkms_5562 1 None None None 119854962 Common - major facilitator superfamily MFS_1 Mkms_5568 14 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119855069 Common - ErfK/YbiS/YcfS/YnhG family protein Mkms_5680 22 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119854894 Nonpathogen - hypothetical protein Mkms_5499 1 None None None 119855153 Nonpathogen - hypothetical protein Mkms_5768 1 None None None 119855071 Common - copper resistance D domain protein Mkms_5682 28 COG3336 COG3336, Predicted membrane protein Function unknown 119855160 Nonpathogen - hypothetical protein Mkms_5775 1 None None None 119855010 Nonpathogen - hypothetical protein Mkms_5617 1 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 119855139 Common - protein of unknown function DUF156 Mkms_5753 52 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 119855019 Common - short-chain dehydrogenase/reductase SDR Mkms_5627 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119855141 Common - transposase, mutator type Mkms_5755 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855004 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mkms_5611 17 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119855024 Nonpathogen - sterol-binding protein Mkms_5632 4 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 119854915 Common - transposase IS116/IS110/IS902 family protein Mkms_5520 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855062 Common - acyltransferase 3 Mkms_5673 71 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 119855093 Common - Heavy metal transport/detoxification protein Mkms_5705 12 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 119855028 Common - aldehyde dehydrogenase Mkms_5636 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119855036 Common - hypothetical protein Mkms_5645 7 COG3777 COG3777, Uncharacterized conserved protein Function unknown 119854973 Common - putative plasmid partitioning protein Mkms_5580 52 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119855152 Nonpathogen - PPE protein Mkms_5767 1 None None None 119855064 Common - putative adenylate/guanylate cyclase Mkms_5675 39 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 119854994 Nonpathogen - hypothetical protein Mkms_5601 1 None None None 119855133 Common - AMP-dependent synthetase and ligase Mkms_5747 179 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119855113 Nonpathogen - hypothetical protein Mkms_5726 3 None None None 119855076 Nonpathogen - putative adenylate/guanylate cyclase Mkms_5688 2 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 119854947 Common - hypothetical protein Mkms_5553 3 None None None 119855095 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mkms_5707 1 None None None 119855159 Common - PPE protein Mkms_5774 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 119854932 Common - hypothetical protein Mkms_5537 17 None None None 119855051 Common - cytochrome c oxidase, subunit III Mkms_5662 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 119854909 Nonpathogen - hypothetical protein Mkms_5514 1 None None None 119855086 Common - protein of unknown function DUF305 Mkms_5698 29 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 119854900 Common - helicase-associated Mkms_5505 29 COG4889 COG4889, Predicted helicase General function prediction only 119855165 Common - protein of unknown function DUF571 Mkms_5780 1 None None None 119855044 Common - transposase IS3/IS911 family protein Mkms_5654 33 None None None 119855067 Common - hypothetical protein Mkms_5678 3 COG3462 COG3462, Predicted membrane protein Function unknown 119855101 Nonpathogen - hypothetical protein Mkms_5713 1 None None None 119854964 Common - putative transcriptional regulator, MerR family Mkms_5570 49 COG0789 SoxR, Predicted transcriptional regulators Transcription 119854896 Nonpathogen - hypothetical protein Mkms_5501 4 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 119855148 Common - NLP/P60 protein Mkms_5763 79 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119855121 Nonpathogen - hypothetical protein Mkms_5734 1 None None None 119854925 Nonpathogen - hypothetical protein Mkms_5530 1 None None None 119855128 Common - hypothetical protein Mkms_5741 64 COG3000 ERG3, Sterol desaturase Lipid metabolism 119854958 Nonpathogen - hypothetical protein Mkms_5564 1 None None None 119855098 Common - ABC transporter related Mkms_5710 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 119855060 Nonpathogen - hypothetical protein Mkms_5671 1 None None None 119855022 Common - Rieske (2Fe-2S) domain protein Mkms_5630 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119855026 Common - ABC-type transport system involved in resistance to organic solvents permease component-like protein Mkms_5634 6 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 119854986 Common - hypothetical protein Mkms_5593 8 None None None 119855035 Common - protein of unknown function DUF35 Mkms_5644 26 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 119855058 Common - peptidase M23B Mkms_5669 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 119855091 Common - hypothetical protein Mkms_5703 10 COG3462 COG3462, Predicted membrane protein Function unknown 119854942 Common - alpha/beta hydrolase fold Mkms_5547 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119854911 Nonpathogen - hypothetical protein Mkms_5516 2 None None None 119855056 Common - peptidase M48, Ste24p Mkms_5667 15 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 119855150 Nonpathogen - hypothetical protein Mkms_5765 1 None None None 119854934 Common - hypothetical protein Mkms_5539 2 None None None 119854975 Common - Cobyrinic acid a,c-diamide synthase Mkms_5582 179 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119854988 Common - hypothetical protein Mkms_5595 5 None None None 119854971 Nonpathogen - hypothetical protein Mkms_5578 1 None None None 119855135 Common - binding-protein-dependent transport systems inner membrane component Mkms_5749 63 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 119855119 Nonpathogen - hypothetical protein Mkms_5732 1 None None None 119854992 Common - putative transcriptional regulatory protein Mkms_5599 3 None None None 119855088 Common - two component transcriptional regulator, winged helix family Mkms_5700 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119855163 Common - protein of unknown function DUF690 Mkms_5778 7 None None None 119854927 Nonpathogen - hypothetical protein Mkms_5532 1 None None None 119854916 Nonpathogen - hypothetical protein Mkms_5521 1 None None None 119855006 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Mkms_5613 22 None None None 119855108 Common - ErfK/YbiS/YcfS/YnhG family protein Mkms_5721 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119855157 Common - cell divisionFtsK/SpoIIIE Mkms_5772 74 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 119855042 Common - transcriptional regulator, MarR family Mkms_5651 107 COG1846 MarR, Transcriptional regulators Transcription 119854929 Nonpathogen - hypothetical protein Mkms_5534 1 None None None 119855074 Common - hypothetical protein Mkms_5685 11 None None None 119854906 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein Mkms_5511 84 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 119855008 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Mkms_5615 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119855096 Common - hypothetical protein Mkms_5708 5 None None None 119854931 Common - ParB domain protein nuclease Mkms_5536 97 COG1475 Spo0J, Predicted transcriptional regulators Transcription 119855169 Nonpathogen - hypothetical protein Mkms_5784 1 None None None 119854919 Nonpathogen - hypothetical protein Mkms_5524 1 None None None 119854910 Nonpathogen - hypothetical protein Mkms_5515 2 None None None 119855083 Nonpathogen - hypothetical protein Mkms_5695 2 None None None 119855048 Common - Abortive infection protein Mkms_5658 26 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 119854943 Common - phage integrase family protein Mkms_5548 5 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119855112 Common - hypothetical protein Mkms_5725 5 None None None 119855106 Common - response regulator receiver protein Mkms_5719 185 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119855130 Common - heavy metal translocating P-type ATPase Mkms_5743 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119854999 Common - DSBA oxidoreductase Mkms_5606 70 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 119854928 Nonpathogen - hypothetical protein Mkms_5533 1 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 119855043 Common - Integrase, catalytic region Mkms_5653 134 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119854926 Nonpathogen - hypothetical protein Mkms_5531 1 None None None 119855075 Common - NLP/P60 protein Mkms_5687 108 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119854936 Common - ABC-1 domain protein Mkms_5541 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 119855038 Common - ring hydroxylating dioxygenase, alpha subunit Mkms_5647 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119854983 Nonpathogen - hypothetical protein Mkms_5590 5 None None None 119855021 Common - hypothetical protein Mkms_5629 34 None None None 119855031 Common - ring hydroxylating dioxygenase, alpha subunit Mkms_5639 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119855164 Common - ATPase involved in chromosome partitioning-like protein Mkms_5779 13 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119854953 Common - PilT protein domain protein Mkms_5559 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119855081 Common - heavy metal translocating P-type ATPase Mkms_5693 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119854965 Common - AAA ATPase Mkms_5571 60 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 119855012 Common - IstB domain protein ATP-binding protein Mkms_5620 95 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119855146 Common - filamentation induced by cAMP protein Fic Mkms_5760 40 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 119855126 Common - Methyltransferase type 11 Mkms_5739 36 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119855094 Common - protein of unknown function DUF156 Mkms_5706 94 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 119855167 Common - hypothetical protein Mkms_5782 3 None None None 119855073 Common - DSBA oxidoreductase Mkms_5684 73 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 119854949 Nonpathogen - hypothetical protein Mkms_5555 1 None None None 119855085 Common - protein of unknown function DUF302 Mkms_5697 44 COG3439 COG3439, Uncharacterized conserved protein Function unknown 119855104 Common - transcriptional repressor, CopY family Mkms_5717 22 COG3682 COG3682, Predicted transcriptional regulator Transcription 119855046 Common - hypothetical protein Mkms_5656 15 None None None 119854904 Common - hypothetical protein Mkms_5509 1 None None None 119855041 Common - 6-phosphogluconate dehydrogenase, NAD-binding Mkms_5650 14 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 119854938 Common - cytochrome P450 Mkms_5543 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 119854977 Nonpathogen - transcription factor WhiB Mkms_5584 1 None None None 119855055 Common - hypothetical protein Mkms_5666 13 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 119855156 Nonpathogen - hypothetical protein Mkms_5771 1 None None None 119855171 Nonpathogen - hypothetical protein Mkms_5786 1 None None None 119854997 Common - ErfK/YbiS/YcfS/YnhG family protein Mkms_5604 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119855110 Common - hypothetical protein Mkms_5723 3 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119854921 Common - transposase IS116/IS110/IS902 family protein Mkms_5526 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855132 Common - Redoxin domain protein Mkms_5746 138 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119855117 Common - transposase, mutator type Mkms_5730 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855116 Common - transposase, mutator type Mkms_5729 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855162 Common - hypothetical protein Mkms_5777 2 None None None 119854957 Nonpathogen - hypothetical protein Mkms_5563 1 None None None 119855078 Common - helix-turn-helix- domain containing protein, AraC type Mkms_5690 50 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119854981 Nonpathogen - hypothetical protein Mkms_5588 1 None None None 119855016 Common - Aldehyde dehydrogenase (NAD(+)) Mkms_5624 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119855003 Common - Rieske (2Fe-2S) domain protein Mkms_5610 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119854913 Nonpathogen - hypothetical protein Mkms_5518 1 None None None 119855137 Common - beta-lactamase domain protein Mkms_5751 204 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119854960 Nonpathogen - hypothetical protein Mkms_5566 1 None None None 119855144 Common - hypothetical protein Mkms_5758 19 None None None 119855014 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Mkms_5622 205 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 119855001 Common - Integrase, catalytic region Mkms_5608 120 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119854955 Nonpathogen - hypothetical protein Mkms_5561 1 None None None 119854945 Common - hypothetical protein Mkms_5551 7 COG3655 COG3655, Predicted transcriptional regulator Transcription 119854967 Common - hypothetical protein Mkms_5573 2 None None None 119854912 Nonpathogen - hypothetical protein Mkms_5517 1 None None None 119854995 Common - hypothetical protein Mkms_5602 5 None None None 119855134 Common - ABC transporter related Mkms_5748 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119855114 Common - histidine kinase Mkms_5727 176 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 119855050 Common - NLP/P60 protein Mkms_5661 134 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119854980 Common - putative transcriptional regulator, XRE family Mkms_5587 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 119854972 Common - putative plasmid partitioning protein Mkms_5579 125 COG1475 Spo0J, Predicted transcriptional regulators Transcription 119854891 Nonpathogen - hypothetical protein Mkms_5496 1 None None None 119854933 Common - transposase IS116/IS110/IS902 family protein Mkms_5538 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855065 Nonpathogen - hypothetical protein Mkms_5676 3 None None None 119855151 Nonpathogen - hypothetical protein Mkms_5766 1 None None None 119855053 Common - Redoxin domain protein Mkms_5664 100 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119855070 Common - cytochrome c biogenesis protein, transmembrane region Mkms_5681 84 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 119854989 Nonpathogen - hypothetical protein Mkms_5596 1 None None None 119854908 Common - transposase IS116/IS110/IS902 family protein Mkms_5513 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119854903 Common - hypothetical protein Mkms_5508 3 None None None 119854979 Common - hypothetical protein Mkms_5586 1 None None None 119855109 Common - hypothetical protein Mkms_5722 50 COG3000 ERG3, Sterol desaturase Lipid metabolism 119855087 Common - integral membrane sensor signal transduction histidine kinase Mkms_5699 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119855123 Common - protein of unknown function DUF305 Mkms_5736 43 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 119855147 Common - hypothetical protein Mkms_5762 4 None None None 119855129 Common - regulatory protein, ArsR Mkms_5742 131 COG0640 ArsR, Predicted transcriptional regulators Transcription 119854968 Common - regulatory protein Mkms_5574 10 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119855103 Common - NLP/P60 protein Mkms_5716 91 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119854990 Nonpathogen - hypothetical protein Mkms_5597 1 None None None 119854922 Nonpathogen - hypothetical protein Mkms_5527 1 None None None 119855122 Common - hypothetical protein Mkms_5735 11 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 119854893 Nonpathogen - hypothetical protein Mkms_5498 3 None None None 119855172 Nonpathogen - hypothetical protein Mkms_5787 1 None None None 119855154 Nonpathogen - hypothetical protein Mkms_5769 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 119855029 Common - drug resistance transporter, EmrB/QacA subfamily Mkms_5637 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119855068 Common - putative transcriptional regulator Mkms_5679 6 None None None 119855034 Common - putative nonspecific lipid-transfer protein Mkms_5643 89 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 119854897 Nonpathogen - hypothetical protein Mkms_5502 3 None None None 119854948 Nonpathogen - hypothetical protein Mkms_5554 1 None None None 119855025 Common - intradiol ring-cleavage dioxygenase Mkms_5633 28 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 119854914 Nonpathogen - hypothetical protein Mkms_5519 1 None None None 119855005 Common - oxidoreductase domain protein Mkms_5612 175 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 119855018 Common - ring hydroxylating dioxygenase, alpha subunit Mkms_5626 84 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119855092 Common - heavy metal translocating P-type ATPase Mkms_5704 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119855037 Common - hypothetical protein Mkms_5646 3 COG1141 Fer, Ferredoxin Energy production and conversion 119854935 Common - transcriptional regulator, TetR family Mkms_5540 5 COG1309 AcrR, Transcriptional regulator Transcription 119855063 Common - heavy metal translocating P-type ATPase Mkms_5674 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119855059 Common - Cytochrome-c oxidase Mkms_5670 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 119855136 Common - extracellular solute-binding protein, family 1 Mkms_5750 126 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 119854974 Nonpathogen - hypothetical protein Mkms_5581 1 None None None 119855077 Common - hypothetical protein Mkms_5689 20 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 119855080 Common - regulatory protein, ArsR Mkms_5692 92 COG0640 ArsR, Predicted transcriptional regulators Transcription 119855166 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Mkms_5781 17 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 119855107 Common - NLP/P60 protein Mkms_5720 108 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119855045 Common - Integrase, catalytic region Mkms_5655 121 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855089 Nonpathogen - hypothetical protein Mkms_5701 1 None None None 119854917 Nonpathogen - hypothetical protein Mkms_5522 1 None None None 119854970 Nonpathogen - hypothetical protein Mkms_5577 2 None None None 119854993 Common - hypothetical protein Mkms_5600 1 COG5654 COG5654, Uncharacterized conserved protein Function unknown 119854901 Common - transposase IS116/IS110/IS902 family protein Mkms_5506 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119855100 Nonpathogen - hypothetical protein Mkms_5712 1 None None None 119855011 Common - hypothetical protein Mkms_5619 50 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119854959 Nonpathogen - helix-turn-helix domain protein Mkms_5565 1 None None None 119855032 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mkms_5640 17 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119855102 Common - response regulator receiver protein Mkms_5715 155 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119854950 Nonpathogen - hypothetical protein Mkms_5556 2 None None None 119854895 Nonpathogen - hypothetical protein Mkms_5500 1 None None None 119855170 Nonpathogen - Type IV secretory pathway VirD4 components-like protein Mkms_5785 4 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 119855066 Nonpathogen - hypothetical protein Mkms_5677 1 None None None 119855127 Common - helix-turn-helix- domain containing protein, AraC type Mkms_5740 38 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119854963 Common - hypothetical protein Mkms_5569 15 None None None 119854924 Nonpathogen - hypothetical protein Mkms_5529 2 None None None 119854985 Common - AAA ATPase Mkms_5592 8 None None None 119854937 Common - ABC-1 domain protein Mkms_5542 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 119855120 Common - hypothetical protein Mkms_5733 3 COG3462 COG3462, Predicted membrane protein Function unknown 119855027 Common - Epoxide hydrolase domain protein Mkms_5635 35 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119854987 Common - transcriptional regulator, XRE family Mkms_5594 34 COG1476 COG1476, Predicted transcriptional regulators Transcription 119855090 Common - multicopper oxidase, type 2 Mkms_5702 123 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 119855023 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mkms_5631 12 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119854899 Nonpathogen - hypothetical protein Mkms_5504 1 None None None 119854941 Common - drug exporters of the RND superfamily-like protein Mkms_5546 26 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 119855140 Common - putative alkylmercury lyase Mkms_5754 6 None None None