Chlorobium phaeobacteroides DSM 266, complete genome NC_008639 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 119356915 Nonpathogen - putative anti-sigma regulatory factor, serine/threonine protein kinase Cpha266_1094 8 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 119358186 Common rplV 50S ribosomal protein L22 Cpha266_2418 208 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 119356366 Common - hypothetical protein Cpha266_0529 18 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 119357319 Nonpathogen - conserved hypothetical cytosolic protein Cpha266_1517 4 None None None 119356788 Nonpathogen - hypothetical protein Cpha266_0960 2 None None None 119357349 Common - RNA polymerase, sigma 54 subunit, RpoN Cpha266_1547 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 119358045 Common - Radical SAM domain protein Cpha266_2273 100 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119356488 Common - hypothetical protein Cpha266_0653 26 COG5340 COG5340, Predicted transcriptional regulator Transcription 119357069 Common - oxidoreductase FAD/NAD(P)-binding domain protein Cpha266_1256 145 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 119356125 Common - ferredoxin, 2Fe-2S Cpha266_0282 56 COG3411 COG3411, Ferredoxin Energy production and conversion 119357294 Common - protein of unknown function DUF323 Cpha266_1490 110 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119357022 Common - Na+/Ca+ antiporter, CaCA family Cpha266_1207 122 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 119356418 Common rpmB 50S ribosomal protein L28 Cpha266_0582 132 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 119356160 Common - FeoA family protein Cpha266_0318 56 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 119356997 Common - ABC transporter related Cpha266_1180 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119357700 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Cpha266_1904 106 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 119357245 Common - hypothetical protein Cpha266_1437 18 None None None 119355982 Common - DsrE family protein Cpha266_0132 44 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 119356743 Nonpathogen - hypothetical protein Cpha266_0915 1 None None None 119356080 Common rpoB DNA-directed RNA polymerase subunit beta Cpha266_0233 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 119357362 Nonpathogen - hypothetical protein Cpha266_1560 5 None None None 119358017 Common - Integrase, catalytic region Cpha266_2241 62 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358191 Common rplC 50S ribosomal protein L3 Cpha266_2423 229 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 119356907 Common truA tRNA pseudouridine synthase A Cpha266_1086 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 119357660 Common - gamma-glutamyl kinase Cpha266_1864 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 119358443 Common - acylphosphatase Cpha266_2679 124 COG1254 AcyP, Acylphosphatases Energy production and conversion 119356944 Nonpathogen - hypothetical protein Cpha266_1124 1 None None None 119357478 Common - NUDIX hydrolase Cpha266_1677 73 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 119356353 Common - protein of unknown function DUF1003 Cpha266_0516 41 COG4420 COG4420, Predicted membrane protein Function unknown 119358288 Common - electron transfer flavoprotein, alpha subunit Cpha266_2520 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 119357269 Nonpathogen - hypothetical protein Cpha266_1461 1 None None None 119357652 Common - anthranilate synthase component I Cpha266_1856 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 119358475 Nonpathogen - hypothetical protein Cpha266_2711 3 None None None 119357183 Nonpathogen - hypothetical protein Cpha266_1374 1 None None None 119357929 Nonpathogen - conserved hypothetical LOC507825 Cpha266_2144 1 None None None 119357797 Nonpathogen - hypothetical protein Cpha266_2004 3 None None None 119358322 Common - hypothetical protein Cpha266_2554 8 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 119357256 Nonpathogen - hypothetical protein Cpha266_1448 1 None None None 119358329 Nonpathogen - hypothetical protein Cpha266_2561 1 None None None 119357210 Common - exodeoxyribonuclease V, beta subunit Cpha266_1401 213 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 119358068 Nonpathogen - hypothetical protein Cpha266_2296 1 None None None 119356016 Common - hypothetical protein Cpha266_0169 8 None None None 119356246 Nonpathogen - hypothetical protein Cpha266_0407 3 None None None 119357594 Common - Uroporphyrinogen-III synthase Cpha266_1797 70 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 119356737 Common - TspO and MBR like proteins Cpha266_0909 30 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 119356571 Common - nitrogenase cofactor biosynthesis protein NifB Cpha266_0737 64 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119357016 Nonpathogen - hypothetical protein Cpha266_1200 1 None None None 119357199 Common - transcriptional modulator of MazE/toxin, MazF Cpha266_1390 28 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 119357911 Common - protein of unknown function DUF81 Cpha266_2123 84 COG0730 COG0730, Predicted permeases General function prediction only 119356218 Common - aspartate alpha-decarboxylase Cpha266_0379 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 119356691 Common - OmpA/MotB domain protein Cpha266_0860 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119358010 Common - protein of unknown function DUF1568 Cpha266_2233 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358110 Common - methyltransferase FkbM family Cpha266_2342 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119358178 Common rpsN 30S ribosomal protein S14 Cpha266_2410 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 119356302 Common - permease Cpha266_0464 108 COG0701 COG0701, Predicted permeases General function prediction only 119357625 Common - anti-sigma-factor antagonist Cpha266_1829 38 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 119356167 Common - transposase, IS4 family protein Cpha266_0325 31 COG5421 COG5421, Transposase DNA replication, recombination, and repair 119357260 Common - Integrase, catalytic region Cpha266_1452 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356208 Common infB translation initiation factor IF-2 Cpha266_0369 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 119356098 Nonpathogen - hypothetical protein Cpha266_0252 10 None None None 119358382 Common - sugar transferase Cpha266_2615 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 119358061 Common recA recombinase A Cpha266_2289 222 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 119356816 Common - PASTA domain containing protein Cpha266_0989 28 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 119357549 Common - IstB domain protein ATP-binding protein Cpha266_1752 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356026 Common - beta-lactamase domain protein Cpha266_0179 207 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119357134 Common - ornithine carbamoyltransferase Cpha266_1323 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 119355919 Nonpathogen - hypothetical protein Cpha266_0069 1 None None None 119356142 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Cpha266_0300 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 119357992 Common - protein of unknown function DUF1568 Cpha266_2213 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358334 Common - SOUL heme-binding protein Cpha266_2566 26 None None None 119355892 Common - carboxyl-terminal protease Cpha266_0042 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 119357902 Common - Integrase, catalytic region Cpha266_2110 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356239 Common - succinyl-CoA synthetase, alpha subunit Cpha266_0400 209 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 119356699 Common - RNA polymerase sigma factor RpoE Cpha266_0868 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119357425 Common - hypothetical protein Cpha266_1624 18 None None None 119356267 Common - Plastoquinol--plastocyanin reductase Cpha266_0429 82 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 119355924 Nonpathogen - hypothetical protein Cpha266_0074 1 None None None 119357676 Nonpathogen - hypothetical protein Cpha266_1880 3 None None None 119357376 Common - sterol desaturase, putative Cpha266_1574 70 COG3000 ERG3, Sterol desaturase Lipid metabolism 119356578 Common - cation diffusion facilitator family transporter Cpha266_0745 207 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 119357730 Nonpathogen - Abortive infection protein Cpha266_1934 5 None None None 119357985 Common - protein of unknown function DUF1568 Cpha266_2204 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119355979 Common - sulfite reductase, dissimilatory-type beta subunit Cpha266_0129 34 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 119357557 Common - MiaB-like tRNA modifying enzyme YliG Cpha266_1760 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 119358436 Common - ammonium transporter Cpha266_2672 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 119358270 Common infC translation initiation factor IF-3 Cpha266_2502 208 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 119356819 Common - inner-membrane translocator Cpha266_0992 107 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 119358005 Common - DEAD/DEAH box helicase domain protein Cpha266_2227 230 COG1201 Lhr, Lhr-like helicases General function prediction only 119355999 Common - Carbon-monoxide dehydrogenase (acceptor) Cpha266_0149 25 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 119358220 Common - von Willebrand factor, type A Cpha266_2452 70 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 119356402 Common - HPr kinase/phosphorylase Cpha266_0566 71 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 119357770 Common - NADH:flavin oxidoreductase/NADH oxidase Cpha266_1977 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 119358373 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Cpha266_2605 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 119357540 Common - protein of unknown function DUF403 Cpha266_1743 83 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 119355872 Common - transposase, IS4 family protein Cpha266_0019 18 None None None 119356138 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cpha266_0296 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 119356341 Common - chromosome segregation protein SMC Cpha266_0504 212 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119358277 Common rplI 50S ribosomal protein L9 Cpha266_2509 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 119358034 Nonpathogen - hypothetical protein Cpha266_2262 1 None None None 119356668 Common - Shikimate kinase Cpha266_0837 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 119357744 Common - hypothetical protein Cpha266_1950 9 None None None 119356801 Common - nickel-dependent hydrogenase, large subunit Cpha266_0973 102 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 119356001 Common mazG nucleoside triphosphate pyrophosphohydrolase Cpha266_0151 157 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 119356880 Common - protein of unknown function DUF195 Cpha266_1053 139 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 119356179 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Cpha266_0340 142 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 119356617 Common - hypothetical protein Cpha266_0785 21 None None None 119356672 Common - ABC transporter related Cpha266_0841 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119356492 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Cpha266_0657 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 119358185 Common rpsC 30S ribosomal protein S3 Cpha266_2417 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 119358500 Common - protein of unknown function DUF1232 Cpha266_2736 19 COG3339 COG3339, Uncharacterized conserved protein Function unknown 119358222 Common - protein of unknown function DUF58 Cpha266_2454 129 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 119356045 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Cpha266_0198 14 None None None 119356364 Common - protein of unknown function DUF374 Cpha266_0527 40 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 119356861 Nonpathogen - hypothetical protein Cpha266_1034 3 None None None 119357071 Nonpathogen - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_1258 24 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 119357204 Nonpathogen - hypothetical protein Cpha266_1395 1 None None None 119358172 Common rplO 50S ribosomal protein L15 Cpha266_2404 204 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 119357382 Common - heat shock protein HtpX Cpha266_1580 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 119357831 Common - diacylglycerol kinase, catalytic region Cpha266_2039 97 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 119356061 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0214 121 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 119357006 Common - hypothetical protein Cpha266_1190 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 119358441 Common - orotidine 5'-phosphate decarboxylase Cpha266_2677 78 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 119356008 Nonpathogen - hypothetical protein Cpha266_0161 3 None None None 119356977 Common - protein of unknown function DUF107 Cpha266_1160 72 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 119356453 Common - multi-sensor hybrid histidine kinase Cpha266_0617 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119356661 Common - Carotene 7,8-desaturase Cpha266_0830 53 COG3349 COG3349, Uncharacterized conserved protein Function unknown 119356477 Common - Integrase, catalytic region Cpha266_0642 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358394 Common - RNA-directed DNA polymerase (Reverse transcriptase) Cpha266_2627 92 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 119358417 Common - Integrase, catalytic region Cpha266_2653 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357785 Nonpathogen - hypothetical protein Cpha266_1992 3 None None None 119357752 Common - NADPH-dependent FMN reductase Cpha266_1959 42 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 119356889 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cpha266_1068 4 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 119357867 Nonpathogen - chlorophyllide reductase subunit Y Cpha266_2075 21 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119357696 Common - malate dehydrogenase Cpha266_1900 192 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 119358389 Common - polysaccharide biosynthesis protein Cpha266_2622 39 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 119357779 Common - hypothetical protein Cpha266_1986 16 COG4887 COG4887, Uncharacterized metal-binding protein conserved in archaea General function prediction only 119358082 Common - magnesium chelatase, H subunit Cpha266_2311 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 119358507 Common rpmH 50S ribosomal protein L34 Cpha266_2743 194 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 119356586 Nonpathogen - hypothetical protein Cpha266_0753 1 None None None 119357739 Common - tryptophan synthase subunit beta Cpha266_1943 229 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 119357442 Common - Queuosine biosynthesis protein Cpha266_1641 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 119358142 Common - hypothetical protein Cpha266_2374 15 None None None 119357794 Common - Ribulose-bisphosphate carboxylase Cpha266_2001 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 119357818 Common - permease YjgP/YjgQ family protein Cpha266_2026 103 COG0795 COG0795, Predicted permeases General function prediction only 119357665 Common - Mur ligase, middle domain protein Cpha266_1869 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 119357890 Common - DNA-3-methyladenine glycosylase Cpha266_2098 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 119355962 Common - Biotin synthase Cpha266_0112 171 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 119356846 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Cpha266_1019 167 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 119357405 Common - hypothetical protein Cpha266_1604 7 None None None 119357586 Common - extracellular solute-binding protein, family 5 Cpha266_1789 188 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119356233 Common - outer surface protein, putative Cpha266_0394 16 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 119358251 Common - Excinuclease ABC, C subunit domain protein Cpha266_2483 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119356756 Common - hypothetical protein Cpha266_0928 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 119356324 Common - hypothetical protein Cpha266_0487 6 None None None 119356077 Common rplA 50S ribosomal protein L1 Cpha266_0230 231 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 119356317 Common - efflux transporter, RND family, MFP subunit Cpha266_0480 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119358488 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Cpha266_2724 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 119357819 Common - protein of unknown function DUF62 Cpha266_2027 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 119357274 Nonpathogen - hypothetical protein Cpha266_1466 4 None None None 119355905 Common - Radical SAM domain protein Cpha266_0055 203 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119356546 Nonpathogen - hypothetical protein Cpha266_0711 1 None None None 119356421 Common - peptidase M24 Cpha266_0585 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119356659 Common - hypothetical protein Cpha266_0828 52 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 119356215 Nonpathogen - hypothetical protein Cpha266_0376 3 None None None 119356348 Nonpathogen - TPR repeat-containing protein Cpha266_0511 13 None None None 119358027 Nonpathogen - hypothetical protein Cpha266_2255 4 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119356528 Common - cation diffusion facilitator family transporter Cpha266_0693 197 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 119356928 Common - holo-acyl-carrier-protein synthase Cpha266_1107 162 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 119357035 Nonpathogen - hypothetical protein Cpha266_1221 1 None None None 119356055 Common - NAD-dependent epimerase/dehydratase Cpha266_0208 72 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119357899 Common - OmpA/MotB domain protein Cpha266_2107 158 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119357924 Common - transposase and inactivated derivatives Cpha266_2139 42 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358123 Common - WD-40 repeat protein Cpha266_2355 64 COG2319 COG2319, FOG: WD40 repeat General function prediction only 119357029 Nonpathogen - hypothetical protein Cpha266_1215 1 None None None 119357535 Common - Squalene/phytoene synthase Cpha266_1738 111 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 119357636 Common - TPR repeat-containing protein Cpha266_1840 191 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 119356681 Common - 3-isopropylmalate dehydrogenase Cpha266_0850 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 119358237 Common moaC bifunctional molybdenum cofactor biosynthesis protein C/molybdopterin-binding protein Cpha266_2469 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 119355940 Common - methionine-R-sulfoxide reductase Cpha266_0090 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 119357702 Nonpathogen - hypothetical protein Cpha266_1906 3 None None None 119358407 Common - protein of unknown function DUF433 Cpha266_2643 26 COG2442 COG2442, Uncharacterized conserved protein Function unknown 119357164 Common - Cytochrome-c peroxidase Cpha266_1353 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 119355949 Nonpathogen - hypothetical protein Cpha266_0099 1 None None None 119357107 Common - hypothetical protein Cpha266_1295 21 None None None 119358153 Nonpathogen - hypothetical protein Cpha266_2385 1 None None None 119356844 Common - Transketolase domain protein Cpha266_1017 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 119357706 Common - NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30 Cpha266_1910 25 None None None 119358076 Common - DNA polymerase III, delta subunit Cpha266_2304 33 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 119356432 Common - Ferritin, Dps family protein Cpha266_0596 82 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 119358463 Common - deoxyhypusine synthase-like protein Cpha266_2699 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 119356295 Common - putative signal transduction protein with Nacht domain Cpha266_0457 99 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 119358497 Common - aminodeoxychorismate lyase Cpha266_2733 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 119357956 Nonpathogen - hypothetical protein Cpha266_2171 1 None None None 119357154 Common - peptidase M15D, vanX D-ala-D-ala dipeptidase Cpha266_1343 55 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 119356637 Common - Auxin Efflux Carrier Cpha266_0806 14 COG0679 COG0679, Predicted permeases General function prediction only 119358129 Common - RNA modification enzyme, MiaB family Cpha266_2361 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 119358169 Common - translation initiation factor IF-1 Cpha266_2401 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 119357407 Common - hypothetical protein Cpha266_1606 8 COG3692 COG3692, Uncharacterized protein conserved in bacteria Function unknown 119358291 Nonpathogen - Type II site-specific deoxyribonuclease Cpha266_2523 1 None None None 119357975 Common - HicA protein Cpha266_2192 23 None None None 119357439 Common - dTMP kinase Cpha266_1638 228 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 119357170 Nonpathogen - hypothetical protein Cpha266_1359 6 None None None 119357488 Nonpathogen - hypothetical protein Cpha266_1687 1 None None None 119356423 Common - DNA-directed DNA polymerase Cpha266_0587 219 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 119355899 Common - F0F1 ATP synthase subunit beta Cpha266_0049 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 119358101 Common - Capsule polysaccharide biosynthesis Cpha266_2331 31 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119357807 Common - nitrogen-fixing NifU domain protein Cpha266_2015 98 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 119358342 Nonpathogen - hypothetical protein Cpha266_2574 2 None None None 119356505 Common - phosphatidylglycerophosphatase A Cpha266_0670 24 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 119355969 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0119 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 119358369 Common - hypothetical protein Cpha266_2601 12 COG5428 COG5428, Uncharacterized conserved small protein Function unknown 119356252 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Cpha266_0414 182 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 119356258 Common - cell cycle protein Cpha266_0420 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 119357127 Common - protein of unknown function DUF214 Cpha266_1316 142 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119357495 Common - prevent-host-death family protein Cpha266_1697 15 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 119357399 Common - GCN5-related N-acetyltransferase Cpha266_1598 99 COG3153 COG3153, Predicted acetyltransferase General function prediction only 119356100 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_0254 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356724 Common - type III restriction enzyme, res subunit Cpha266_0896 117 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 119355931 Common - hypothetical protein Cpha266_0081 3 None None None 119356760 Nonpathogen - hypothetical protein Cpha266_0932 1 None None None 119358131 Common - aminotransferase, class V Cpha266_2363 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 119356963 Nonpathogen - hypothetical protein Cpha266_1146 1 None None None 119356201 Common - phosphatidate cytidylyltransferase Cpha266_0362 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 119357852 Common - CRISPR-associated protein Cas2 Cpha266_2060 53 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119357327 Common - signal recognition particle protein Cpha266_1525 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 119356475 Common - filamentation induced by cAMP protein Fic Cpha266_0640 21 COG3177 COG3177, Uncharacterized conserved protein Function unknown 119356286 Common - periplasmic binding protein Cpha266_0448 85 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119357051 Common - Methyltransferase type 11 Cpha266_1238 104 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119356489 Common - hypothetical protein Cpha266_0654 21 COG2253 COG2253, Uncharacterized conserved protein Function unknown 119356820 Common - ABC transporter related Cpha266_0993 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 119357933 Common - transketolase Cpha266_2148 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 119356970 Common - transposase and inactivated derivatives Cpha266_1153 42 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357610 Common - Radical SAM domain protein Cpha266_1814 120 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119356810 Common - Superoxide dismutase Cpha266_0983 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 119356188 Common - GtrA family protein Cpha266_0349 23 COG2246 COG2246, Predicted membrane protein Function unknown 119356790 Common - NADH-quinone oxidoreductase, B subunit Cpha266_0962 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 119357503 Common - protein of unknown function DUF559 Cpha266_1705 148 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 119356518 Common - hypothetical protein Cpha266_0683 10 None None None 119356482 Common - hypothetical protein Cpha266_0647 10 COG2886 COG2886, Uncharacterized small protein Function unknown 119356557 Common - hydrogenase assembly chaperone hypC/hupF Cpha266_0723 81 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 119355975 Common - SirA family protein Cpha266_0125 102 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119357948 Common - tRNA/rRNA methyltransferase (SpoU) Cpha266_2163 206 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 119356355 Common - pyruvate phosphate dikinase Cpha266_0518 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 119356521 Common - fructose-1,6-bisphosphatase Cpha266_0686 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 119357572 Nonpathogen - hypothetical protein Cpha266_1775 1 None None None 119357450 Common - hypothetical protein Cpha266_1649 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 119357202 Common - hypothetical protein Cpha266_1393 5 None None None 119358144 Common - histidinol-phosphate phosphatase family protein Cpha266_2376 120 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 119357308 Nonpathogen - hypothetical protein Cpha266_1506 5 None None None 119357444 Common - uncharacterized domain 1 Cpha266_1643 90 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 119358021 Common - protein of unknown function DUF1568 Cpha266_2246 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356929 Common - adenylosuccinate lyase Cpha266_1108 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 119356952 Nonpathogen - hypothetical protein Cpha266_1132 2 None None None 119356595 Nonpathogen - acetoacetate decarboxylase Cpha266_0763 3 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 119356279 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Cpha266_0441 71 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 119357334 Common - thiamine-phosphate pyrophosphorylase Cpha266_1532 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 119356563 Common thiH thiamine biosynthesis protein ThiH Cpha266_0729 55 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 119357190 Nonpathogen - putative transcriptional regulator, CopG family Cpha266_1381 1 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 119358249 Nonpathogen - hypothetical protein Cpha266_2481 1 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119358235 Common - hypothetical protein Cpha266_2467 15 None None None 119356508 Common - alpha amylase, catalytic region Cpha266_0673 35 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 119356439 Common - MotA/TolQ/ExbB proton channel Cpha266_0603 124 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 119357954 Common - nickel-dependent hydrogenase, large subunit Cpha266_2169 109 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 119357041 Common - hypothetical protein Cpha266_1227 9 None None None 119356754 Nonpathogen - hypothetical protein Cpha266_0926 3 None None None 119355912 Common - NADPH-dependent FMN reductase Cpha266_0062 14 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 119357179 Nonpathogen - hypothetical protein Cpha266_1370 1 None None None 119356339 Common - NusB antitermination factor Cpha266_0502 129 COG0781 NusB, Transcription termination factor Transcription 119356902 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Cpha266_1081 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 119358035 Nonpathogen - sulfatase Cpha266_2263 2 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 119356032 Common - alpha/beta hydrolase fold Cpha266_0185 100 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119357657 Common - peptide deformylase Cpha266_1861 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 119357724 Common - protein of unknown function DUF306, Meta and HslJ Cpha266_1928 34 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 119357014 Common - tRNA guanosine-2'-O-methyltransferase Cpha266_1198 207 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 119356806 Common - Thioredoxin domain Cpha266_0979 230 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 119357714 Common - homocitrate synthase Cpha266_1918 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 119358352 Common - NLP/P60 protein Cpha266_2584 137 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119356260 Common - RNA modification enzyme, MiaB family Cpha266_0422 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 119357623 Common - anti-sigma-factor antagonist Cpha266_1827 53 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 119358202 Nonpathogen - hypothetical protein Cpha266_2434 2 None None None 119356393 Common - hypothetical protein Cpha266_0557 12 None None None 119357207 Common - restriction modification system DNA specificity domain Cpha266_1398 56 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 119356858 Common - DNA-directed DNA polymerase Cpha266_1031 172 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 119358314 Common - threonine synthase Cpha266_2546 195 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 119357339 Common - Leucyl aminopeptidase Cpha266_1537 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 119356405 Common ruvB Holliday junction DNA helicase B Cpha266_0569 217 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 119357689 Common - protein of unknown function DUF323 Cpha266_1893 102 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119358427 Common - DNA gyrase, A subunit Cpha266_2663 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 119355866 Common - hypothetical protein Cpha266_0011 4 None None None 119356768 Common - permease YjgP/YjgQ family protein Cpha266_0940 69 COG0795 COG0795, Predicted permeases General function prediction only 119356716 Nonpathogen - hypothetical protein Cpha266_0888 1 None None None 119357913 Common - regulatory protein, ArsR Cpha266_2126 136 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119356379 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like Cpha266_0542 17 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 119355926 Common - Integrase, catalytic region Cpha266_0076 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356934 Common - Na+/Pi-cotransporter Cpha266_1114 90 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 119356893 Common - GCN5-related N-acetyltransferase Cpha266_1072 29 None None None 119356835 Common - transcriptional regulator, Fis family Cpha266_1008 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 119357371 Common - UbiA prenyltransferase Cpha266_1569 9 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 119357286 Nonpathogen - hypothetical protein Cpha266_1480 1 None None None 119358138 Common - protein of unknown function DUF558 Cpha266_2370 203 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 119355950 Common - succinate dehydrogenase/fumarate reductase iron-sulfur subunit Cpha266_0100 57 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 119358360 Common - Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase Cpha266_2592 103 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119357643 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Cpha266_1847 58 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 119358230 Common - Radical SAM domain protein Cpha266_2462 95 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119356727 Common - ATPase associated with various cellular activities, AAA_5 Cpha266_0899 93 COG0714 COG0714, MoxR-like ATPases General function prediction only 119356856 Nonpathogen - pyruvoyl-dependent arginine decarboxylase Cpha266_1029 22 COG1945 COG1945, Uncharacterized conserved protein Function unknown 119356133 Common - hypothetical protein Cpha266_0290 12 COG5304 COG5304, Uncharacterized protein conserved in bacteria Function unknown 119358096 Common - Hemolysin-type calcium-binding region Cpha266_2326 114 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119356186 Common - lipid A biosynthesis acyltransferase Cpha266_0347 122 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 119357317 Nonpathogen - hypothetical protein Cpha266_1515 4 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 119357390 Common - protein of unknown function DUF796 Cpha266_1588 29 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 119358349 Common - protein of unknown function DUF205 Cpha266_2581 169 COG0344 COG0344, Predicted membrane protein Function unknown 119357514 Nonpathogen - hypothetical protein Cpha266_1716 1 None None None 119357564 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Cpha266_1767 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 119357346 Common - 3-dehydroquinate dehydratase Cpha266_1544 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 119357843 Nonpathogen - hypothetical protein Cpha266_2051 1 None None None 119357417 Nonpathogen - hypothetical protein Cpha266_1616 1 None None None 119358415 Nonpathogen - hypothetical protein Cpha266_2651 1 None None None 119358445 Common - putative membrane-associated zinc metalloprotease Cpha266_2681 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 119356559 Common - hydrogenase expression/formation protein HypE Cpha266_0725 154 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 119356299 Common - regulatory protein, ArsR Cpha266_0461 46 COG0640 ArsR, Predicted transcriptional regulators Transcription 119356272 Nonpathogen - hypothetical protein Cpha266_0434 3 None None None 119356089 Nonpathogen - hypothetical protein Cpha266_0242 3 None None None 119357871 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Cpha266_2079 150 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 119358421 Common - hypothetical protein Cpha266_2657 19 None None None 119356739 Common - nitrogenase-associated protein Cpha266_0911 18 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 119356640 Nonpathogen - hypothetical protein Cpha266_0809 3 None None None 119358255 Nonpathogen - protein of unknown function DUF177 Cpha266_2487 6 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 119357369 Common - NADH:flavin oxidoreductase/NADH oxidase Cpha266_1567 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 119355886 Common - DNA gyrase, B subunit Cpha266_0036 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 119357800 Common - uridylate kinase Cpha266_2008 246 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 119357455 Common - major facilitator superfamily MFS_1 Cpha266_1654 73 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 119358309 Common - competence/damage-inducible protein CinA Cpha266_2541 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 119357360 Nonpathogen - hypothetical protein Cpha266_1558 1 None None None 119357433 Common - dihydrolipoamide dehydrogenase Cpha266_1632 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119357520 Common - 5,10-methylenetetrahydrofolate reductase Cpha266_1723 165 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 119356642 Common - L-aspartate oxidase Cpha266_0811 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 119355992 Common - uroporphyrin-III C-methyltransferase Cpha266_0142 206 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 119357527 Nonpathogen - hypothetical protein Cpha266_1730 2 None None None 119357464 Nonpathogen - hypothetical protein Cpha266_1663 3 None None None 119356877 Common - short-chain dehydrogenase/reductase SDR Cpha266_1050 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119358434 Common - peptidase C1A, papain Cpha266_2670 11 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 119357267 Common - bifunctional methionine sulfoxide reductase B/A protein Cpha266_1459 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 119357197 Common - hypothetical protein Cpha266_1388 9 None None None 119356981 Common - methylmalonyl-CoA mutase Cpha266_1164 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 119356995 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like Cpha266_1178 166 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119357861 Common - phage integrase family protein Cpha266_2069 175 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119356350 Common - NUDIX hydrolase Cpha266_0513 166 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119356647 Common - FAD linked oxidase domain protein Cpha266_0816 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 119357671 Common - modification methylase, HemK family Cpha266_1875 223 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 119358320 Common - Redoxin domain protein Cpha266_2552 219 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119358260 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Cpha266_2492 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119356326 Common - putative oxidoreductase Cpha266_0489 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 119356735 Nonpathogen - hypothetical protein Cpha266_0907 15 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 119356359 Common - Sigma-70, region 4 type 2 Cpha266_0522 7 None None None 119357238 Common - CRISPR-associated protein Cas2 Cpha266_1430 45 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119357858 Nonpathogen - hypothetical protein Cpha266_2066 11 None None None 119357904 Common - Integrase, catalytic region Cpha266_2112 152 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356194 Common - glycosyl transferase, group 1 Cpha266_0355 33 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357253 Common - hypothetical protein Cpha266_1445 13 None None None 119357999 Common - Integrase, catalytic region Cpha266_2221 111 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357446 Common - Integrase, catalytic region Cpha266_1645 140 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356274 Common - TOBE domain protein Cpha266_0436 74 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 119356450 Common - coproporphyrinogen III oxidase Cpha266_0614 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 119356227 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Cpha266_0388 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 119356019 Common - DNA mismatch repair protein MutL Cpha266_0172 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 119356592 Nonpathogen - hypothetical protein Cpha266_0759 1 None None None 119358473 Common - ATP synthase F0, A subunit Cpha266_2709 179 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 119357718 Common - MIP family channel proteins Cpha266_1922 127 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 119356693 Common - membrane lipoprotein lipid attachment site Cpha266_0862 67 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 119357654 Common - signal peptidase I Cpha266_1858 200 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 119357373 Common - Rubrerythrin Cpha266_1571 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 119358049 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Cpha266_2277 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 119358300 Common - heavy metal translocating P-type ATPase Cpha266_2532 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119356162 Common - transposase and inactivated derivatives Cpha266_0320 39 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357616 Common - polysaccharide biosynthesis protein Cpha266_1820 26 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 119357558 Common radC DNA repair protein RadC Cpha266_1761 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 119358039 Common - peptidylprolyl isomerase, FKBP-type Cpha266_2267 154 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 119358375 Common - putative acetyltransferase Cpha266_2607 92 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 119356304 Common - arsenical-resistance protein Cpha266_0466 139 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 119356147 Common - amine oxidase Cpha266_0305 65 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119357608 Common - glycosyl transferase, group 1 Cpha266_1812 226 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357310 Common - protein of unknown function DUF214 Cpha266_1508 41 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119357909 Nonpathogen - hypothetical protein Cpha266_2117 1 None None None 119358119 Nonpathogen - hypothetical protein Cpha266_2351 11 None None None 119357547 Common - 5'-Nucleotidase domain protein Cpha266_1750 151 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 119356288 Common - hypothetical protein Cpha266_0450 4 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 119356244 Common - hypothetical protein Cpha266_0405 7 None None None 119356872 Common - acriflavin resistance protein Cpha266_1045 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119358056 Common - alanine racemase Cpha266_2284 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 119357674 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Cpha266_1878 229 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119357185 Common - addiction module toxin, RelE/StbE family Cpha266_1376 41 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 119358281 Common - exodeoxyribonuclease III Xth Cpha266_2513 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 119356237 Common - undecaprenyl diphosphate synthase Cpha266_0398 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 119357990 Common - IstB domain protein ATP-binding protein Cpha266_2210 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357873 Common - protein of unknown function DUF167 Cpha266_2081 27 COG1872 COG1872, Uncharacterized conserved protein Function unknown 119356577 Common nifH nitrogenase reductase Cpha266_0744 72 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 119356057 Nonpathogen - hypothetical protein Cpha266_0210 1 None None None 119356014 Common - Glu/Leu/Phe/Val dehydrogenase, C-terminal domain protein Cpha266_0167 178 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 119357410 Nonpathogen - hypothetical protein Cpha266_1609 1 None None None 119356745 Common - sodium/hydrogen exchanger Cpha266_0917 213 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 119357555 Nonpathogen - hypothetical protein Cpha266_1758 6 None None None 119357292 Common - protein of unknown function DUF1568 Cpha266_1487 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356786 Common - ferrochelatase Cpha266_0958 7 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 119356281 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Cpha266_0443 202 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 119357215 Nonpathogen - hypothetical protein Cpha266_1406 1 None None None 119358043 Common - acetyltransferase, CysE/LacA/LpxA/NodL family Cpha266_2271 196 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 119358405 Common - hypothetical protein Cpha266_2641 15 COG4691 StbC, Plasmid stability protein General function prediction only 119358267 Common - glycoside hydrolase, family 3 domain protein Cpha266_2499 184 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 119356905 Common - PfkB domain protein Cpha266_1084 124 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 119356917 Nonpathogen - hypothetical protein Cpha266_1096 2 None None None 119357804 Common rplM 50S ribosomal protein L13 Cpha266_2012 228 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 119358247 Common - Excinuclease ABC, C subunit domain protein Cpha266_2479 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119356602 Nonpathogen - hypothetical protein Cpha266_0770 1 None None None 119357357 Nonpathogen - hypothetical protein Cpha266_1555 1 None None None 119357983 Nonpathogen - hypothetical protein Cpha266_2202 1 None None None 119356416 Nonpathogen - hypothetical protein Cpha266_0580 3 None None None 119356075 Common - NusG antitermination factor Cpha266_0228 215 COG0250 NusG, Transcription antiterminator Transcription 119358224 Nonpathogen - hypothetical protein Cpha266_2456 3 None None None 119357746 Common - killer suppression protein HigA, putative Cpha266_1952 6 None None None 119356337 Nonpathogen - hypothetical protein Cpha266_0500 3 None None None 119358032 Common - AAA ATPase, central domain protein Cpha266_2260 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 119356119 Common - SEFIR domain protein Cpha266_0275 16 None None None 119358502 Common - ROK family protein Cpha266_2738 149 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 119357662 Common - ABC transporter related Cpha266_1866 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119356106 Common - transposase, IS4 family protein Cpha266_0262 18 None None None 119358210 Common - glycosyl transferase, group 1 Cpha266_2442 53 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119358354 Common - Ppx/GppA phosphatase Cpha266_2586 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 119357243 Common - CRISPR-associated protein Cas5 family Cpha266_1435 36 None None None 119356143 Common - penicillin-binding protein, 1A family Cpha266_0301 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 119357303 Common - hypothetical protein Cpha266_1501 31 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 119357221 Common - histidinol-phosphate aminotransferase Cpha266_1412 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 119356486 Common - metallophosphoesterase Cpha266_0651 31 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 119356374 Common - Prephenate dehydratase Cpha266_0537 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 119358279 Common - single-strand binding protein Cpha266_2511 204 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 119356628 Common - hypothetical protein Cpha266_0797 40 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119356226 Common - ABC transporter related Cpha266_0387 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119357228 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cpha266_1420 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 119356663 Common - glutamine synthetase, catalytic region Cpha266_0832 79 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 119356975 Nonpathogen - hypothetical protein Cpha266_1158 1 None None None 119357249 Nonpathogen - YcfA family protein Cpha266_1441 3 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 119357568 Common - hypothetical protein Cpha266_1771 8 None None None 119355960 Common - N-acetylmuramoyl-L-alanine amidase Cpha266_0110 176 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 119356169 Common - IstB domain protein ATP-binding protein Cpha266_0329 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119358188 Common rplB 50S ribosomal protein L2 Cpha266_2420 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 119356942 Common - ABC transporter related Cpha266_1122 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119356195 Common - hypothetical protein Cpha266_0356 4 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 119356494 Common - Rieske (2Fe-2S) domain protein Cpha266_0659 47 COG3349 COG3349, Uncharacterized conserved protein Function unknown 119357380 Common - protein of unknown function DUF1568 Cpha266_1578 45 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 119356833 Nonpathogen - hypothetical protein Cpha266_1006 2 None None None 119356887 Common - geranylgeranyl reductase Cpha266_1066 140 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 119356584 Nonpathogen - hypothetical protein Cpha266_0751 2 None None None 119356063 Nonpathogen - hypothetical protein Cpha266_0216 2 None None None 119356560 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Cpha266_0726 230 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119355894 Common - geranylgeranyl reductase Cpha266_0044 109 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 119358080 Common - Integrase, catalytic region Cpha266_2309 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356583 Common - PASTA domain containing protein Cpha266_0750 32 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 119358194 Common - elongation factor G Cpha266_2426 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 119355995 Common - binding-protein-dependent transport systems inner membrane component Cpha266_0145 185 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 119356900 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_1079 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358499 Common - Rhomboid family protein Cpha266_2735 161 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 119357576 Nonpathogen - hypothetical protein Cpha266_1779 3 None None None 119356232 Common rho transcription termination factor Rho Cpha266_0393 199 COG1158 Rho, Transcription termination factor Transcription 119357400 Nonpathogen - hypothetical protein Cpha266_1599 1 None None None 119357922 Common - MT-A70 family protein Cpha266_2137 22 COG4725 IME4, Transcriptional activator, adenine-specific DNA methyltransferase Signal transduction mechanisms / Transcription 119355988 Nonpathogen - hypothetical protein Cpha266_0138 15 None None None 119356848 Common - Endonuclease/exonuclease/phosphatase Cpha266_1021 19 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 119356346 Common - transcriptional regulator, BadM/Rrf2 family Cpha266_0509 135 COG1959 COG1959, Predicted transcriptional regulator Transcription 119356538 Common - alanine racemase domain protein Cpha266_0703 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 119356544 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0709 159 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 119357679 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Cpha266_1883 190 COG0388 COG0388, Predicted amidohydrolase General function prediction only 119358486 Common - cell cycle protein Cpha266_2722 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 119357276 Common - nitroreductase Cpha266_1469 106 COG0778 NfnB, Nitroreductase Energy production and conversion 119358217 Common - AAA ATPase, central domain protein Cpha266_2449 213 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 119356082 Common - acetyl-CoA carboxylase, biotin carboxylase Cpha266_0235 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 119356651 Common - chaperonin Cpn10 Cpha266_0820 6 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 119357533 Common - protein of unknown function UPF0054 Cpha266_1736 56 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 119358151 Common - IstB domain protein ATP-binding protein Cpha266_2383 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119358397 Common - glycosyl transferase, family 2 Cpha266_2632 115 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119356241 Nonpathogen - hypothetical protein Cpha266_0402 3 None None None 119356922 Common - short-chain dehydrogenase/reductase SDR Cpha266_1101 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119355907 Common - hypothetical protein Cpha266_0057 29 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 119356451 Common - oxidoreductase domain protein Cpha266_0615 189 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 119357649 Nonpathogen - hypothetical protein Cpha266_1853 3 None None None 119357634 Nonpathogen - hypothetical protein Cpha266_1838 3 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 119357694 Common rplU 50S ribosomal protein L21 Cpha266_1898 86 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 119357427 Nonpathogen - hypothetical protein Cpha266_1626 1 None None None 119358453 Nonpathogen - hypothetical protein Cpha266_2689 1 None None None 119358438 Common - Ferritin, Dps family protein Cpha266_2674 55 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 119356457 Common - ABC transporter related Cpha266_0622 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119356954 Nonpathogen - hypothetical protein Cpha266_1134 3 None None None 119356448 Common - protein of unknown function DUF985 Cpha266_0612 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 119356994 Common - peptide chain release factor 3 Cpha266_1177 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 119356803 Common - hydrogenase maturation protease Cpha266_0975 56 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 119356413 Nonpathogen - twin-arginine translocation protein, TatA/E family subunit Cpha266_0577 3 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 119358451 Common - PAS/PAC sensor signal transduction histidine kinase Cpha266_2687 172 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119357206 Common - hypothetical protein Cpha266_1397 10 None None None 119356776 Nonpathogen - hypothetical protein Cpha266_0948 4 None None None 119357585 Common - putative PAS/PAC sensor protein Cpha266_1788 160 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 119357298 Common - hypothetical protein Cpha266_1494 7 None None None 119358243 Common - ABC transporter related Cpha266_2475 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 119356362 Common - isochorismatase hydrolase Cpha266_0525 91 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 119358108 Common - hypothetical protein Cpha266_2340 11 None None None 119356136 Common - hypothetical protein Cpha266_0294 5 None None None 119357143 Common - sugar-phosphate isomerases, RpiB/LacA/LacB family Cpha266_1332 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 119358088 Common - Excinuclease ABC, C subunit domain protein Cpha266_2317 32 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119357078 Common - phosphoribosylformylglycinamidine synthase II Cpha266_1265 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 119357946 Nonpathogen - UspA domain protein Cpha266_2161 7 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119356463 Common - Glutamate synthase (ferredoxin) Cpha266_0628 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 119357008 Common - biotin/lipoyl attachment domain-containing protein Cpha266_1192 175 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 119356674 Common - membrane protein involved in aromatic hydrocarbon degradation Cpha266_0843 31 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 119357028 Common - ATPase, AAA+ superfamily Cpha266_1213 53 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119357175 Common - hypothetical protein Cpha266_1365 4 None None None 119358008 Common - hypothetical protein Cpha266_2231 4 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119356029 Common - hypothetical protein Cpha266_0182 8 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119356676 Common - alkylhydroperoxidase like protein, AhpD family Cpha266_0845 4 COG2128 COG2128, Uncharacterized conserved protein Function unknown 119357741 Nonpathogen - hypothetical protein Cpha266_1947 1 None None None 119356043 Common - hypothetical protein Cpha266_0196 23 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 119356955 Common - Integrase, catalytic region Cpha266_1136 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356172 Nonpathogen - hypothetical protein Cpha266_0333 3 None None None 119356610 Common - transcriptional regulator, TetR family Cpha266_0778 32 COG1309 AcrR, Transcriptional regulator Transcription 119356751 Common - Nucleotidyl transferase Cpha266_0923 238 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 119357783 Common - transcriptional regulator, TraR/DksA family Cpha266_1990 101 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 119357754 Common - deoxyribodipyrimidine photolyase Cpha266_1961 68 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 119355870 Common - transposase, IS4 family protein Cpha266_0017 18 None None None 119356615 Common - ATPase (AAA+ superfamily) Cpha266_0783 49 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119357354 Common - Uncharacterised conserved protein UCP025560 Cpha266_1552 25 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 119356932 Common - major facilitator superfamily MFS_1 Cpha266_1111 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119356897 Common - cyclopropane fatty acyl phospholipid synthase Cpha266_1076 135 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 119357159 Common - Integrase, catalytic region Cpha266_1348 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119355977 Common - DsrC family protein Cpha266_0127 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 119357304 Nonpathogen - Type II site-specific deoxyribonuclease Cpha266_1502 2 None None None 119357814 Common - LemA family protein Cpha266_2022 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 119358312 Common - F0F1 ATP synthase subunit alpha Cpha266_2544 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 119356796 Common - NADH-ubiquinone oxidoreductase, chain 4L Cpha266_0968 136 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 119357505 Common - hypothetical protein Cpha266_1707 11 COG0388 COG0388, Predicted amidohydrolase General function prediction only 119357562 Common - seryl-tRNA synthetase Cpha266_1765 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 119355916 Nonpathogen - hypothetical protein Cpha266_0066 2 None None None 119357687 Common purT phosphoribosylglycinamide formyltransferase 2 Cpha266_1891 200 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 119358106 Common - transposase IS3/IS911 family protein Cpha266_2336 11 None None None 119357141 Common - amidohydrolase Cpha266_1330 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 119357452 Nonpathogen - DNA polymerase III, gamma/tau subunit Cpha266_1651 2 None None None 119356983 Common - acetyl-CoA carboxylase alpha subunit-like Cpha266_1166 219 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 119357332 Common - Endoribonuclease L-PSP Cpha266_1530 98 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 119355923 Common - DNA methylase N-4/N-6 domain protein Cpha266_0073 90 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 119357120 Common - conserved hypothetical protein 245 Cpha266_1309 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 119357325 Common - 16S rRNA processing protein RimM Cpha266_1523 128 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 119357570 Nonpathogen - hypothetical protein Cpha266_1773 6 None None None 119356109 Nonpathogen - hypothetical protein Cpha266_0265 2 None None None 119358423 Common - IstB domain protein ATP-binding protein Cpha266_2659 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357962 Common - SMC domain protein Cpha266_2178 58 COG4637 COG4637, Predicted ATPase General function prediction only 119357047 Nonpathogen - hypothetical protein Cpha266_1234 2 None None None 119356565 Common - thiamine biosynthesis protein ThiS Cpha266_0731 18 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 119357177 Common - Na+/Ca+ antiporter, CaCA family Cpha266_1368 119 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 119356265 Common - glutamyl-tRNA synthetase Cpha266_0427 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 119357386 Common - putative methyltransferase Cpha266_1584 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 119358376 Common - GDP-mannose 4,6-dehydratase Cpha266_2608 224 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 119356630 Common - glycosyl transferase, group 1 Cpha266_0799 227 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357397 Common - Beta-lactamase Cpha266_1596 38 COG2602 COG2602, Beta-lactamase class D Defense mechanisms 119357722 Common - IstB domain protein ATP-binding protein Cpha266_1926 95 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357969 Common - plasmid stabilization system Cpha266_2186 20 COG3668 ParE, Plasmid stabilization system protein General function prediction only 119356705 Nonpathogen - ferredoxin Cpha266_0877 5 COG0633 Fdx, Ferredoxin Energy production and conversion 119355997 Common - ABC transporter related Cpha266_0147 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 119357129 Common - diguanylate cyclase Cpha266_1318 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 119357959 Common - Integrase, catalytic region Cpha266_2174 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357630 Common - multi-sensor signal transduction histidine kinase Cpha266_1834 225 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119356024 Common - succinate dehydrogenase or fumarate reductase, flavoprotein subunit Cpha266_0177 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 119356799 Common - proton-translocating NADH-quinone oxidoreductase, chain N Cpha266_0971 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 119356385 Nonpathogen - hypothetical protein Cpha266_0549 1 None None None 119358127 Common - phosphatidate cytidylyltransferase Cpha266_2359 32 COG0170 SEC59, Dolichol kinase Lipid metabolism 119357437 Common - short-chain dehydrogenase/reductase SDR Cpha266_1636 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 119358159 Common - GTPase EngB Cpha266_2391 193 COG0218 COG0218, Predicted GTPase General function prediction only 119356552 Nonpathogen - hypothetical protein Cpha266_0718 3 None None None 119355984 Common - DsrH family protein Cpha266_0134 26 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 119358465 Common - beta-phosphoglucomutase family hydrolase Cpha266_2701 187 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 119356653 Nonpathogen - hypothetical protein Cpha266_0822 4 None None None 119356512 Common aat leucyl/phenylalanyl-tRNA--protein transferase Cpha266_0677 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 119357977 Common - protein of unknown function DUF433 Cpha266_2195 11 COG2442 COG2442, Uncharacterized conserved protein Function unknown 119357162 Common - transposase family protein Cpha266_1351 32 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358163 Common rplQ 50S ribosomal protein L17 Cpha266_2395 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 119357431 Common - magnesium chelatase ATPase subunit D Cpha266_1630 68 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 119357659 Common - small multidrug resistance protein Cpha266_1863 146 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 119355864 Common - Integrase, catalytic region Cpha266_0008 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356091 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cpha266_0244 231 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 119357123 Common - protein of unknown function UPF0016 Cpha266_1312 74 COG2119 COG2119, Predicted membrane protein Function unknown 119356635 Nonpathogen - hypothetical protein Cpha266_0804 1 None None None 119356536 Common - eIF-2B alpha/beta/delta-related uncharacterized proteins Cpha266_0701 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 119356722 Nonpathogen - hypothetical protein Cpha266_0894 1 None None None 119357768 Nonpathogen - hypothetical protein Cpha266_1975 2 None None None 119357493 Nonpathogen - hypothetical protein Cpha266_1694 1 None None None 119356501 Common - Ham1 family protein Cpha266_0666 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 119357519 Common - ComEC/Rec2-related protein Cpha266_1722 183 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 119356924 Common - beta-ketoacyl synthase Cpha266_1103 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119357111 Common - protein of unknown function DUF323 Cpha266_1299 120 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 119358265 Common - HNH endonuclease Cpha266_2497 103 COG1403 McrA, Restriction endonuclease Defense mechanisms 119357344 Common - primosomal protein N' Cpha266_1542 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 119356854 Nonpathogen - hypothetical protein Cpha266_1027 1 None None None 119357290 Common - protein of unknown function DUF1568 Cpha266_1484 47 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357880 Common - isochorismate synthases Cpha266_2088 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119358073 Common - arsenite-activated ATPase ArsA Cpha266_2301 97 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 119355956 Common - aconitate hydratase 1 Cpha266_0106 221 COG1048 AcnA, Aconitase A Energy production and conversion 119358447 Nonpathogen - hypothetical protein Cpha266_2683 3 None None None 119357081 Nonpathogen - hypothetical protein Cpha266_1268 1 None None None 119357841 Nonpathogen - CRISPR-associated protein, Csm2 family Cpha266_2049 1 COG1421 COG1421, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119357284 Common - hypothetical protein Cpha266_1477 4 None None None 119356980 Common - arginine/ornithine transport system ATPase Cpha266_1163 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 119357169 Common - uncharacterized conserved coiled coil protein Cpha266_1358 11 None None None 119356910 Common - D-3-phosphoglycerate dehydrogenase Cpha266_1089 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 119357419 Nonpathogen - hypothetical protein Cpha266_1618 1 None None None 119357897 Common - cytochrome B561 Cpha266_2105 25 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 119356711 Common - NUDIX hydrolase Cpha266_0883 109 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119356688 Common - Biopolymer transport protein ExbD/TolR Cpha266_0857 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 119358193 Common - elongation factor Tu Cpha266_2425 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 119358253 Common - Excinuclease ABC, C subunit domain protein Cpha266_2485 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119356131 Common - hypothetical protein Cpha266_0288 4 None None None 119357251 Common - hypothetical protein Cpha266_1443 20 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 119357970 Common - prevent-host-death family protein Cpha266_2187 29 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 119357885 Common - O-succinylbenzoate-CoA ligase Cpha266_2093 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119356163 Common - ferrous iron transport protein B Cpha266_0321 153 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 119357916 Nonpathogen - hypothetical protein Cpha266_2129 2 None None None 119355884 Common secF preprotein translocase subunit SecF Cpha266_0034 202 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 119358141 Common - UDP-N-acetylglucosamine acyltransferase Cpha266_2373 169 COG1043 LpxA, Acyl- acyl carrier protein 119355937 Common - major facilitator superfamily MFS_1 Cpha266_0087 190 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119358302 Common - protein of unknown function DUF900, hydrolase family protein Cpha266_2534 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 119357195 Nonpathogen - hypothetical protein Cpha266_1386 5 None None None 119356321 Common - ABC transporter related Cpha266_0484 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 119357525 Nonpathogen - hypothetical protein Cpha266_1728 1 None None None 119357892 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Cpha266_2100 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 119357944 Common - ABC transporter related Cpha266_2159 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119355888 Common - Ribonuclease H Cpha266_0038 209 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 119356966 Common - hypothetical protein Cpha266_1149 15 COG2253 COG2253, Uncharacterized conserved protein Function unknown 119356644 Nonpathogen - pyruvoyl-dependent arginine decarboxylase Cpha266_0813 23 COG1945 COG1945, Uncharacterized conserved protein Function unknown 119357412 Nonpathogen - hypothetical protein Cpha266_1611 1 None None None 119356747 Common - alpha/beta hydrolase fold Cpha266_0919 114 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119356974 Common - Methyltransferase type 11 Cpha266_1157 105 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119356590 Common - permease Cpha266_0757 29 COG0701 COG0701, Predicted permeases General function prediction only 119358206 Common - polysaccharide biosynthesis protein Cpha266_2438 103 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 119356808 Common - conserved hypothetical protein 95 Cpha266_0981 123 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 119356357 Common - isoprenoid biosynthesis protein with amidotransferase-like domain Cpha266_0520 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 119356718 Common - hypothetical protein Cpha266_0890 6 None None None 119357716 Common - aldo/keto reductase Cpha266_1920 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 119357512 Nonpathogen - hypothetical protein Cpha266_1714 4 None None None 119358026 Nonpathogen - hypothetical protein Cpha266_2254 2 None None None 119357378 Common - DNA polymerase III, epsilon subunit Cpha266_1576 192 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 119357152 Common - CHAD domain containing protein Cpha266_1341 36 COG5607 COG5607, Uncharacterized conserved protein Function unknown 119356969 Common - prophage antirepressor Cpha266_1152 11 None None None 119357236 Common - IstB domain protein ATP-binding protein Cpha266_1428 95 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357629 Common - putative PAS/PAC sensor protein Cpha266_1833 215 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 119356372 Common - peptidase M23B Cpha266_0535 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 119358204 Nonpathogen - hypothetical protein Cpha266_2436 1 None None None 119355877 Common - DNA polymerase B region Cpha266_0027 66 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 119357337 Common - hypothetical protein Cpha266_1535 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119357763 Common - hypothetical protein Cpha266_1970 9 None None None 119356895 Common - Uncharacterised conserved protein UCP016719 Cpha266_1074 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 119357805 Common engA GTP-binding protein EngA Cpha266_2013 226 COG1160 COG1160, Predicted GTPases General function prediction only 119356525 Common - glycosyl transferase, family 39 Cpha266_0690 92 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 119358492 Nonpathogen - hypothetical protein Cpha266_2728 3 None None None 119356030 Common - outer membrane efflux protein Cpha266_0183 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119357209 Common - exodeoxyribonuclease V, alpha subunit Cpha266_1400 126 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 119356812 Common - dephospho-CoA kinase Cpha266_0985 208 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 119356159 Nonpathogen - FeoA family protein Cpha266_0317 2 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 119356766 Common - helix-turn-helix domain protein Cpha266_0938 2 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 119356250 Nonpathogen - hypothetical protein Cpha266_0412 1 None None None 119356002 Common - short-chain dehydrogenase/reductase SDR Cpha266_0152 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 119358148 Nonpathogen - hypothetical protein Cpha266_2380 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 119357491 Common - hypothetical protein Cpha266_1692 2 None None None 119358293 Common - hypothetical protein Cpha266_2525 9 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 119358283 Nonpathogen - hypothetical protein Cpha266_2515 3 None None None 119356608 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Cpha266_0776 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119357212 Common - hypothetical protein Cpha266_1403 17 COG3428 COG3428, Predicted membrane protein Function unknown 119356609 Common - efflux transporter, RND family, MFP subunit Cpha266_0777 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119356469 Common - putative transcriptional regulator Cpha266_0634 73 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119358226 Common - preprotein translocase, YajC subunit Cpha266_2458 183 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 119358261 Common - acyl carrier protein Cpha266_2493 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119356004 Common - Rhodanese domain protein Cpha266_0154 112 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119357850 Common - RelA/SpoT domain protein Cpha266_2058 30 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 119355971 Common - protein of unknown function DUF81 Cpha266_0121 40 COG0730 COG0730, Predicted permeases General function prediction only 119356462 Common - phosphoglycerate mutase 1 family Cpha266_0627 159 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 119355909 Nonpathogen - SH3, type 3 domain protein Cpha266_0059 4 None None None 119358245 Common - ferric uptake regulator, Fur family Cpha266_2477 54 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 119357910 Common - transcriptional regulator, AbrB family Cpha266_2120 14 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 119356345 Common - Methyltransferase type 12 Cpha266_0508 4 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 119356283 Common - transport system permease protein Cpha266_0445 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119356539 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Cpha266_0704 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 119357471 Nonpathogen - hypothetical protein Cpha266_1670 1 None None None 119356874 Nonpathogen - hypothetical protein Cpha266_1047 3 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 119356886 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Cpha266_1064 224 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 119356468 Common - helicase domain protein Cpha266_0633 188 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119357031 Common - plasmid stabilization system Cpha266_1217 24 COG3668 ParE, Plasmid stabilization system protein General function prediction only 119357002 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family Cpha266_1186 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 119356407 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Cpha266_0571 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 119358024 Common - hypothetical protein Cpha266_2250 2 None None None 119358356 Common - AMP-dependent synthetase and ligase Cpha266_2588 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119358483 Nonpathogen - hypothetical protein Cpha266_2719 1 None None None 119357401 Common - hypothetical protein Cpha266_1600 5 None None None 119356307 Nonpathogen - hypothetical protein Cpha266_0470 1 None None None 119358385 Common - Carbamoylphosphate synthase large subunit (split gene in MJ)-like Cpha266_2618 27 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 119356650 Common - Rod shape-determining protein MreC Cpha266_0819 105 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 119356397 Common - 7-cyano-7-deazaguanine reductase Cpha266_0561 113 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 119356884 Common - geranylgeranyl reductase Cpha266_1062 131 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 119356778 Common - Redoxin domain protein Cpha266_0950 105 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119358504 Common - 60 kDa inner membrane insertion protein Cpha266_2740 210 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 119356678 Common - 3-isopropylmalate dehydratase, small subunit Cpha266_0847 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 119356753 Common - phenylalanyl-tRNA synthetase, beta subunit Cpha266_0925 227 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 119356224 Common - isopentenyl pyrophosphate isomerase Cpha266_0385 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 119357297 Common - phage Gp37Gp68 family protein Cpha266_1493 42 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 119357781 Common - Transglycosylase-associated protein Cpha266_1988 16 COG2261 COG2261, Predicted membrane protein Function unknown 119358214 Common - Exonuclease VII, small subunit Cpha266_2446 20 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 119357974 Common - HicB family protein Cpha266_2191 31 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 119356613 Common - hypothetical protein Cpha266_0781 2 None None None 119357757 Nonpathogen - hypothetical protein Cpha266_1964 1 None None None 119358196 Common rpsL 30S ribosomal protein S12 Cpha266_2428 245 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 119358464 Common - tryptophanyl-tRNA synthetase Cpha266_2700 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119357543 Common - type I secretion outer membrane protein, TolC family Cpha266_1746 138 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119358175 Common rplR 50S ribosomal protein L18 Cpha266_2407 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 119357711 Common - hypothetical protein Cpha266_1915 6 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 119356455 Common - outer membrane efflux protein Cpha266_0620 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119356041 Common - aldolase Cpha266_0194 66 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 119358295 Common - hypothetical protein Cpha266_2527 5 None None None 119356153 Common - NAD-dependent epimerase/dehydratase Cpha266_0311 83 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356347 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0510 40 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 119357692 Common - DNA mismatch repair protein Cpha266_1896 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 119357928 Common - hypothetical protein Cpha266_2143 25 None None None 119356985 Common - AMP-dependent synthetase and ligase Cpha266_1168 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 119356957 Common - hypothetical protein Cpha266_1139 23 None None None 119357887 Common - Dihydrodipicolinate reductase Cpha266_2095 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 119356248 Common - Phosphomannomutase Cpha266_0410 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 119358234 Common - pyrroline-5-carboxylate reductase Cpha266_2466 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 119357734 Nonpathogen - hypothetical protein Cpha266_1938 3 None None None 119357091 Nonpathogen - hypothetical protein Cpha266_1278 1 None None None 119355878 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Cpha266_0028 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 119357863 Common - ribosome small subunit-dependent GTPase A Cpha266_2071 163 COG1162 COG1162, Predicted GTPases General function prediction only 119355966 Common bioD dithiobiotin synthetase Cpha266_0116 49 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 119355996 Common - ABC transporter related Cpha266_0146 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 119356474 Common - domain of unknown function DUF1738 Cpha266_0639 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 119358398 Common - transposase, IS4 family protein Cpha266_2634 48 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357270 Nonpathogen - hypothetical protein Cpha266_1462 1 None None None 119358377 Common - S23 ribosomal protein Cpha266_2609 32 None None None 119357009 Common - internalin-related protein Cpha266_1193 29 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 119357614 Common - glycosyl transferase, group 1 Cpha266_1818 186 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357580 Common - NAD-dependent epimerase/dehydratase Cpha266_1783 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356212 Common rpsO 30S ribosomal protein S15 Cpha266_0373 216 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 119357531 Nonpathogen - hypothetical protein Cpha266_1734 5 None None None 119357538 Common - NAD-dependent epimerase/dehydratase Cpha266_1741 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356296 Nonpathogen - hypothetical protein Cpha266_0458 2 None None None 119356867 Common - phosphate ABC transporter, inner membrane subunit PstA Cpha266_1040 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 119357060 Common - putative PAS/PAC sensor protein Cpha266_1247 44 None None None 119356541 Common - hydrolase, TatD family Cpha266_0706 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 119355901 Common - phosphoenolpyruvate carboxykinase Cpha266_0051 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 119356189 Common - glycosyl transferase, family 2 Cpha266_0350 212 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119357789 Common - dTDP-4-dehydrorhamnose reductase Cpha266_1996 165 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 119357815 Common - (p)ppGpp synthetase I, SpoT/RelA Cpha266_2023 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 119357677 Nonpathogen - hypothetical protein Cpha266_1881 1 None None None 119358341 Common - NAD(+) kinase Cpha266_2573 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 119358086 Common - magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase Cpha266_2315 109 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119358448 Common - nitroreductase Cpha266_2684 132 COG0778 NfnB, Nitroreductase Energy production and conversion 119358120 Common - Class I peptide chain release factor Cpha266_2352 117 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 119356800 Common - hydrogenase (NiFe) small subunit HydA Cpha266_0972 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 119357232 Common - nitroreductase Cpha266_1424 71 COG0778 NfnB, Nitroreductase Energy production and conversion 119357239 Common - CRISPR-associated protein Cas1 Cpha266_1431 99 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119357222 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Cpha266_1413 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119356992 Common - Radical SAM domain protein Cpha266_1175 29 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119358041 Common - FAD dependent oxidoreductase Cpha266_2269 6 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 119357791 Common - glucose-1-phosphate thymidylyltransferase Cpha266_1998 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 119357241 Common - CRISPR-associated protein, Csd2 family Cpha266_1433 55 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119357065 Common - putative PAS/PAC sensor protein Cpha266_1252 34 None None None 119358092 Common - Integrase, catalytic region Cpha266_2321 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358316 Common - Riboflavin synthase Cpha266_2548 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 119356444 Nonpathogen - hypothetical protein Cpha266_0608 3 None None None 119358051 Nonpathogen - hypothetical protein Cpha266_2279 3 None None None 119357583 Common - response regulator receiver protein Cpha266_1786 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 119357265 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis Cpha266_1457 24 COG1433 COG1433, Uncharacterized conserved protein Function unknown 119358471 Common - ATP synthase F0, B subunit Cpha266_2707 164 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 119355986 Nonpathogen - Nitrate reductase, gamma subunit Cpha266_0136 22 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 119357621 Common - glycosyl transferase, family 2 Cpha266_1825 116 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119356117 Common - Integrase, catalytic region Cpha266_0273 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356129 Nonpathogen - hypothetical protein Cpha266_0286 2 None None None 119356914 Common - hypothetical protein Cpha266_1093 8 None None None 119358403 Common - S23 ribosomal protein Cpha266_2639 32 None None None 119358057 Common - helix-hairpin-helix motif Cpha266_2285 47 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 119357798 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Cpha266_2005 14 None None None 119356108 Common - hypothetical protein Cpha266_0264 18 None None None 119357173 Nonpathogen - hypothetical protein Cpha266_1362 1 None None None 119356553 Common pyrB aspartate carbamoyltransferase catalytic subunit Cpha266_0719 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 119358458 Nonpathogen - hypothetical protein Cpha266_2694 1 None None None 119356050 Common - aminoglycoside phosphotransferase Cpha266_0203 89 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 119357708 Common - magnesium and cobalt transport protein CorA Cpha266_1912 177 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 119356197 Common - glycosyl transferase, group 1 Cpha266_0358 155 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357705 Common - hypothetical protein Cpha266_1909 40 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 119356626 Common - CsbD family protein Cpha266_0795 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 119356376 Common - crossover junction endodeoxyribonuclease RuvC Cpha266_0539 196 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 119358212 Common - acetyltransferase Cpha266_2444 87 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 119358274 Nonpathogen - hypothetical protein Cpha266_2506 1 None None None 119357225 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_1416 111 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 119357026 Common - hypothetical protein Cpha266_1211 23 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 119358011 Nonpathogen - hypothetical protein Cpha266_2235 1 None None None 119358365 Common - 6-phosphofructokinase Cpha266_2597 150 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 119356329 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Cpha266_0492 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 119356174 Common - tryptophan synthase subunit beta Cpha266_0335 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 119356581 Nonpathogen - hypothetical protein Cpha266_0748 1 None None None 119358180 Common rplX 50S ribosomal protein L24 Cpha266_2412 209 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 119356122 Nonpathogen - hypothetical protein Cpha266_0278 1 None None None 119357367 Common - methylated-DNA--protein-cysteine methyltransferase Cpha266_1565 218 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 119358063 Common - peptidase M16 domain protein Cpha266_2291 195 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 119356636 Nonpathogen - hypothetical protein Cpha266_0805 1 None None None 119357218 Common - peptidyl-tRNA hydrolase Cpha266_1409 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 119357560 Common - short-chain dehydrogenase/reductase SDR Cpha266_1763 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 119357980 Common - hypothetical protein Cpha266_2199 4 None None None 119356767 Common - DNA methylase N-4/N-6 domain protein Cpha266_0939 93 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 119357552 Common - hypothetical protein Cpha266_1755 5 None None None 119357749 Common - transposase IS3/IS911 family protein Cpha266_1955 37 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356059 Nonpathogen - hypothetical protein Cpha266_0212 1 None None None 119356811 Nonpathogen - hypothetical protein Cpha266_0984 3 None None None 119358326 Common - protein of unknown function DUF190 Cpha266_2558 45 COG1993 COG1993, Uncharacterized conserved protein Function unknown 119357668 Common - chaperone protein DnaJ Cpha266_1872 234 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 119356164 Common - hypothetical protein Cpha266_0322 8 None None None 119355862 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_0006 72 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356146 Common - transcription activator, effector binding Cpha266_0304 19 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 119358050 Common rpsU 30S ribosomal protein S21 Cpha266_2278 33 None None None 119357279 Nonpathogen - hypothetical protein Cpha266_1472 7 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 119356695 Common - chaperone protein DnaK Cpha266_0864 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 119357411 Nonpathogen - hypothetical protein Cpha266_1610 1 None None None 119356657 Nonpathogen - chlorosome envelope protein H Cpha266_0826 3 None None None 119358219 Common - von Willebrand factor, type A Cpha266_2451 59 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 119356710 Common - MscS Mechanosensitive ion channel Cpha266_0882 57 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 119356827 Common - cobalamin 5'-phosphate synthase Cpha266_1000 147 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 119356746 Common - protein tyrosine phosphatase Cpha266_0918 136 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 119356148 Common - hypothetical protein Cpha266_0306 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 119357681 Common - Sporulation domain protein Cpha266_1885 7 None None None 119357194 Nonpathogen - hypothetical protein Cpha266_1385 1 None None None 119357915 Common - hypothetical protein Cpha266_2128 12 COG5561 COG5561, Predicted metal-binding protein Function unknown 119356598 Common - DNA polymerase, beta domain protein region Cpha266_0766 12 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 119356950 Common - N-6 DNA methylase Cpha266_1130 155 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 119356310 Common - ABC transporter related Cpha266_0473 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119356574 Common - nitrogenase molybdenum-iron protein alpha chain Cpha266_0741 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119358336 Common - Integrase, catalytic region Cpha266_2568 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356591 Common - regulatory protein, ArsR Cpha266_0758 182 COG0640 ArsR, Predicted transcriptional regulators Transcription 119357355 Common - hypothetical protein Cpha266_1553 12 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 119356206 Common - protein of unknown function DUF150 Cpha266_0367 51 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 119356011 Common - putative methyltransferase Cpha266_0164 23 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 119357448 Nonpathogen - hypothetical protein Cpha266_1647 5 None None None 119356496 Common - Mammalian cell entry related domain protein Cpha266_0661 29 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 119356221 Nonpathogen - methyltransferase FkbM family Cpha266_0382 3 None None None 119358117 Nonpathogen - hypothetical protein Cpha266_2349 1 None None None 119356096 Common - putative transcriptional regulator, XRE family Cpha266_0249 13 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 119357187 Nonpathogen - hypothetical protein Cpha266_1378 1 None None None 119357656 Common - methionyl-tRNA formyltransferase Cpha266_1860 223 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 119357688 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cpha266_1892 28 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 119358000 Common - protein of unknown function DUF433 Cpha266_2222 11 COG2442 COG2442, Uncharacterized conserved protein Function unknown 119357997 Nonpathogen - hypothetical protein Cpha266_2219 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119356390 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Cpha266_0554 210 COG0313 COG0313, Predicted methyltransferases General function prediction only 119357773 Common - glycosyl transferase, family 2 Cpha266_1980 166 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119357524 Common - hypothetical protein Cpha266_1727 23 None None None 119358351 Common - aspartate kinase Cpha266_2583 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 119356561 Nonpathogen - hypothetical protein Cpha266_0727 1 None None None 119357458 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Cpha266_1657 142 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 119358146 Common - hypothetical protein Cpha266_2378 10 None None None 119356411 Common - dihydrodipicolinate synthase Cpha266_0575 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 119356758 Nonpathogen - hypothetical protein Cpha266_0930 1 None None None 119356335 Common - Ppx/GppA phosphatase Cpha266_0498 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 119356401 Common - hypothetical protein Cpha266_0565 10 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 119358048 Common - alpha/beta hydrolase fold Cpha266_2276 153 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119357686 Common - ABC transporter related Cpha266_1890 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119357606 Nonpathogen - metal dependent phosphohydrolase Cpha266_1809 3 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 119357374 Nonpathogen - hypothetical protein Cpha266_1572 2 None None None 119358208 Nonpathogen - hypothetical protein Cpha266_2440 4 None None None 119357330 Common - cyclase/dehydrase Cpha266_1528 15 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 119355860 Common - DNA replication and repair protein RecF Cpha266_0003 170 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 119356534 Common - cytochrome d ubiquinol oxidase, subunit II Cpha266_0699 157 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 119356445 Common - acetylornithine and succinylornithine aminotransferases Cpha266_0609 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 119357093 Common - IstB domain protein ATP-binding protein Cpha266_1280 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357313 Common - FAD linked oxidase domain protein Cpha266_1511 203 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 119356783 Common - Methyltransferase type 12 Cpha266_0955 36 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 119356967 Common - hypothetical protein Cpha266_1150 9 COG5340 COG5340, Predicted transcriptional regulator Transcription 119357237 Common - Integrase, catalytic region Cpha266_1429 62 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357498 Common - hypothetical protein Cpha266_1700 39 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 119356036 Common - short-chain dehydrogenase/reductase SDR Cpha266_0189 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 119357889 Common - Cobyrinic acid a,c-diamide synthase Cpha266_2097 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119357530 Common - ferredoxin Cpha266_1733 21 COG0633 Fdx, Ferredoxin Energy production and conversion 119357350 Common - hypothetical protein Cpha266_1548 9 None None None 119357982 Nonpathogen - hypothetical protein Cpha266_2201 2 None None None 119356765 Common - hypothetical protein Cpha266_0937 2 None None None 119358456 Nonpathogen - hypothetical protein Cpha266_2692 1 None None None 119357602 Common - chorismate synthase Cpha266_1805 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 119356890 Common - acid phosphatase (Class B) Cpha266_1069 26 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 119357766 Common - N-acetyltransferase Cpha266_1973 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 119358272 Common rplT 50S ribosomal protein L20 Cpha266_2504 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 119357995 Common - hypothetical protein Cpha266_2216 23 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356085 Common - histone family protein DNA-binding protein Cpha266_0238 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 119358318 Nonpathogen - hypothetical protein Cpha266_2550 1 None None None 119357775 Common - protein of unknown function DUF214 Cpha266_1982 85 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 119357942 Common - Patatin Cpha266_2157 123 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119357960 Common - transcriptional regulator/antitoxin, MazE Cpha266_2175 20 COG2336 MazE, Growth regulator Signal transduction mechanisms 119357086 Common - RNP-1 like RNA-binding protein Cpha266_1273 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 119357648 Common - Triose-phosphate isomerase Cpha266_1852 222 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 119357053 Common - transcriptional regulator, TetR family Cpha266_1240 58 COG1309 AcrR, Transcriptional regulator Transcription 119357289 Common - IstB domain protein ATP-binding protein Cpha266_1483 95 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357282 Nonpathogen - hypothetical protein Cpha266_1475 2 None None None 119356831 Common - iron-containing alcohol dehydrogenase Cpha266_1004 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 119358311 Common - ATP synthase F1, gamma subunit Cpha266_2543 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 119357847 Common - CRISPR-associated protein Cas2 Cpha266_2055 37 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119357140 Common - fructose-bisphosphate aldolase Cpha266_1329 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 119356158 Common - hypothetical protein Cpha266_0316 7 None None None 119356523 Nonpathogen - hypothetical protein Cpha266_0688 10 COG0392 COG0392, Predicted integral membrane protein Function unknown 119356690 Common - WD40 domain protein beta Propeller Cpha266_0859 165 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 119358285 Common - protein of unknown function DUF224, cysteine-rich region domain protein Cpha266_2517 95 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 119355955 Common - histidine triad (HIT) protein Cpha266_0105 226 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 119356697 Common - regulatory protein, ArsR Cpha266_0866 127 COG0640 ArsR, Predicted transcriptional regulators Transcription 119356633 Common - Queuosine biosynthesis protein Cpha266_0802 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 119357894 Common metH B12-dependent methionine synthase Cpha266_2102 178 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 119357018 Common - hypothetical protein Cpha266_1202 7 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 119358268 Common - chlorophyllide reductase subunit Z Cpha266_2500 28 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119357866 Common - ribosome recycling factor Cpha266_2074 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 119358072 Nonpathogen - chlorosome envelope protein C Cpha266_2300 3 None None None 119357257 Common - bacteriochlorophyll/chlorophyll a synthase Cpha266_1449 67 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 119357828 Nonpathogen - transcriptional regulator, Fis family Cpha266_2036 20 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 119356948 Common - type III restriction enzyme, res subunit Cpha266_1128 103 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 119357875 Common - citrate synthase I Cpha266_2083 194 COG0372 GltA, Citrate synthase Energy production and conversion 119357895 Nonpathogen - hypothetical protein Cpha266_2103 1 None None None 119358345 Common - ATPase AAA-2 domain protein Cpha266_2577 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 119358305 Common - alpha amylase, catalytic region Cpha266_2537 76 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 119358419 Common - protein of unknown function DUF132 Cpha266_2655 29 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119356073 Common - short-chain dehydrogenase/reductase SDR Cpha266_0226 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 119357414 Nonpathogen - hypothetical protein Cpha266_1613 1 None None None 119357720 Nonpathogen - hypothetical protein Cpha266_1924 1 None None None 119356065 Common - Diaminopimelate epimerase Cpha266_0218 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 119357070 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_1257 31 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 119356511 Common - nitroreductase Cpha266_0676 35 COG0778 NfnB, Nitroreductase Energy production and conversion 119358466 Common argS arginyl-tRNA synthetase Cpha266_2702 246 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119357430 Common - magnesium chelatase, H subunit Cpha266_1629 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 119357761 Common - Phenylacetate--CoA ligase Cpha266_1968 123 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 119357938 Common - domain of unknown function DUF1745 Cpha266_2153 46 COG3287 COG3287, Uncharacterized conserved protein Function unknown 119358379 Common - transposase and inactivated derivatives Cpha266_2612 44 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358164 Common - DNA-directed RNA polymerase subunit alpha Cpha266_2396 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 119355932 Common - DNA mismatch endonuclease vsr Cpha266_0082 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 119356706 Common - transcription-repair coupling factor Cpha266_0878 222 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 119357133 Common - acetylglutamate kinase Cpha266_1322 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 119357510 Common - N-6 DNA methylase Cpha266_1712 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 119357759 Common - Indolepyruvate ferredoxin oxidoreductase Cpha266_1966 93 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 119357932 Common - hypothetical protein Cpha266_2147 10 COG5634 COG5634, Uncharacterized conserved protein Function unknown 119358105 Common - Hemolysin-type calcium-binding region Cpha266_2335 119 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119358370 Nonpathogen - hypothetical protein Cpha266_2602 2 None None None 119356103 Nonpathogen - hypothetical protein Cpha266_0258 2 None None None 119357949 Nonpathogen - hypothetical protein Cpha266_2164 3 None None None 119358494 Common - hypothetical protein Cpha266_2730 118 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 119357979 Common - HpcH/HpaI aldolase Cpha266_2198 107 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 119357125 Common - GCN5-related N-acetyltransferase Cpha266_1314 86 COG0456 RimI, Acetyltransferases General function prediction only 119356472 Common - hypothetical protein Cpha266_0637 7 None None None 119357428 Common - phage integrase family protein Cpha266_1627 106 COG0582 XerC, Integrase DNA replication, recombination, and repair 119356386 Common - acetate--CoA ligase Cpha266_0550 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 119355935 Common - 4'-phosphopantetheinyl transferase Cpha266_0085 65 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 119357750 Common - hypothetical protein Cpha266_1956 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 119356114 Nonpathogen - hypothetical protein Cpha266_0270 1 None None None 119357395 Common - oxaloacetate decarboxylase Cpha266_1594 164 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 119357967 Common - hypothetical protein Cpha266_2184 12 COG5304 COG5304, Uncharacterized protein conserved in bacteria Function unknown 119357870 Common xseA exodeoxyribonuclease VII large subunit Cpha266_2078 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 119356130 Common - hypothetical protein Cpha266_0287 16 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 119357483 Common - Extracellular ligand-binding receptor Cpha266_1682 130 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 119357824 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Cpha266_2032 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 119357147 Common pyrC dihydroorotase Cpha266_1336 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 119357150 Common - NAD-dependent epimerase/dehydratase Cpha266_1339 186 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119358157 Common - protein of unknown function DUF77 Cpha266_2389 22 COG0011 COG0011, Uncharacterized conserved protein Function unknown 119356264 Common - ATP-dependent metalloprotease FtsH Cpha266_0426 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 119357157 Nonpathogen - hypothetical protein Cpha266_1346 1 None None None 119356652 Common - quinolinate synthetase Cpha266_0821 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 119356255 Common - cytidylate kinase Cpha266_0417 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 119356713 Common - protein of unknown function DUF179 Cpha266_0885 129 COG1678 COG1678, Putative transcriptional regulator Transcription 119356504 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cpha266_0669 208 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 119357776 Nonpathogen - hypothetical protein Cpha266_1983 2 None None None 119357114 Common - DEAD/DEAH box helicase domain protein Cpha266_1302 82 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 119357812 Common - protein of unknown function DUF477 Cpha266_2020 53 COG3762 COG3762, Predicted membrane protein Function unknown 119358228 Common - Serine--glyoxylate transaminase Cpha266_2460 157 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 119356686 Common - protein of unknown function DUF92, transmembrane Cpha266_0855 18 COG1836 COG1836, Predicted membrane protein Function unknown 119357590 Common - GTP-binding protein TypA Cpha266_1793 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 119356606 Common - hypothetical protein Cpha266_0774 22 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119357546 Common - type I secretion system ATPase Cpha266_1749 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 119357836 Nonpathogen - CRISPR-associated protein Cas6 Cpha266_2044 25 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 119357113 Common - helicase domain protein Cpha266_1301 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119356899 Nonpathogen - hypothetical protein Cpha266_1078 1 None None None 119357829 Common - glutamine amidotransferase of anthranilate synthase Cpha266_2037 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 119356732 Common - protein of unknown function DUF45 Cpha266_0904 139 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 119358124 Common - glycosyl transferase, family 2 Cpha266_2356 172 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119357508 Common - restriction modification system DNA specificity domain Cpha266_1710 92 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 119357421 Nonpathogen - hypothetical protein Cpha266_1620 1 None None None 119356438 Common - DNA primase Cpha266_0602 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119356814 Common - Sec-independent protein translocase, TatC subunit Cpha266_0987 203 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 119357485 Common - ABC transporter related Cpha266_1684 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119357040 Common - plasmid stabilization system Cpha266_1226 17 COG3668 ParE, Plasmid stabilization system protein General function prediction only 119357138 Common - argininosuccinate lyase Cpha266_1327 228 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 119356938 Common - putative L-threonine-O-3-phosphate decarboxylase Cpha266_1118 175 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 119357389 Nonpathogen - hypothetical protein Cpha266_1587 3 None None None 119357103 Common - hypothetical protein Cpha266_1290 12 COG2944 COG2944, Predicted transcriptional regulator Transcription 119358136 Common - Nucleoside-diphosphate kinase Cpha266_2368 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 119357465 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_1664 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356824 Common - Methenyltetrahydrofolate cyclohydrolase Cpha266_0997 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 119357045 Common - putative PAS/PAC sensor protein Cpha266_1232 114 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 119356428 Common - hypothetical protein Cpha266_0592 3 None None None 119355947 Common - transcriptional regulator, NifA subfamily, Fis Family Cpha266_0097 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 119357972 Common - hypothetical protein Cpha266_2189 61 COG3943 COG3943, Virulence protein General function prediction only 119357323 Common rplS 50S ribosomal protein L19 Cpha266_1521 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 119355921 Nonpathogen - helix-turn-helix domain protein Cpha266_0071 13 COG2944 COG2944, Predicted transcriptional regulator Transcription 119357108 Common - protein of unknown function DUF87 Cpha266_1296 106 COG0433 COG0433, Predicted ATPase General function prediction only 119357073 Nonpathogen - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_1260 37 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 119356748 Common - Phosphoribosylanthranilate isomerase Cpha266_0920 198 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 119355898 Common - H+-transporting two-sector ATPase, delta/epsilon subunit Cpha266_0048 134 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 119358007 Nonpathogen - hypothetical protein Cpha266_2229 1 None None None 119357917 Common - protein of unknown function DUF156 Cpha266_2130 49 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 119356622 Nonpathogen - hypothetical protein Cpha266_0790 1 None None None 119356298 Common - protein of unknown function DUF323 Cpha266_0460 98 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119358084 Common - magnesium chelatase Cpha266_2313 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 119358478 Common - O-methyltransferase, family 2 Cpha266_2714 46 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 119357728 Common - glycosyl transferase, family 2 Cpha266_1932 133 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119356655 Common - LmbE family protein Cpha266_0824 58 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 119357536 Common lysS lysyl-tRNA synthetase Cpha266_1739 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 119356949 Common - putative transcriptional regulator Cpha266_1129 52 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119357926 Nonpathogen - hypothetical protein Cpha266_2141 6 COG3427 COG3427, Uncharacterized conserved protein Function unknown 119356368 Common - Indole-3-glycerol-phosphate synthase Cpha266_0531 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 119356087 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Cpha266_0240 113 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 119357787 Nonpathogen - hypothetical protein Cpha266_1994 5 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 119358391 Nonpathogen - hypothetical protein Cpha266_2624 1 None None None 119356588 Common - catalase/peroxidase HPI Cpha266_0755 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 119356843 Common - conserved hypothetical protein 95 Cpha266_1016 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 119357272 Common - Activator of Hsp90 ATPase 1 family protein Cpha266_1464 8 COG4891 COG4891, Uncharacterized conserved protein Function unknown 119356028 Common - acriflavin resistance protein Cpha266_0181 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119356587 Common - ferric uptake regulator, Fur family Cpha266_0754 170 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 119358412 Nonpathogen - hypothetical protein Cpha266_2648 1 None None None 119358332 Common - Polysulphide reductase, NrfD Cpha266_2564 33 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 119357309 Common - efflux transporter, RND family, MFP subunit Cpha266_1507 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119357690 Common - hypothetical protein Cpha266_1894 9 None None None 119356213 Common - hypothetical protein Cpha266_0374 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 119356048 Nonpathogen - Proto-chlorophyllide reductase 57 kD subunit Cpha266_0201 3 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 119357638 Common - secretion protein HlyD family protein Cpha266_1842 151 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119357423 Nonpathogen - hypothetical protein Cpha266_1622 1 None None None 119358338 Common - Holliday junction resolvase YqgF Cpha266_2570 137 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 119357817 Common - peptidase M16 domain protein Cpha266_2025 168 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 119356269 Common - alpha amylase, catalytic region Cpha266_0431 18 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 119358145 Common - glycogen/starch synthases, ADP-glucose type Cpha266_2377 134 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 119357565 Common - sun protein Cpha266_1768 216 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 119356771 Common - CMP/dCMP deaminase, zinc-binding Cpha266_0943 86 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 119357645 Common - PUCC protein Cpha266_1849 23 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 119357097 Common - hypothetical protein Cpha266_1284 15 None None None 119357589 Common - chlorophyllide reductase iron protein subunit X Cpha266_1792 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 119356548 Common - UspA domain protein Cpha266_0713 133 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119357321 Common - AMP-dependent synthetase and ligase Cpha266_1519 218 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 119357000 Common - protein of unknown function DUF344 Cpha266_1184 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 119358002 Common - protein of unknown function DUF1568 Cpha266_2224 29 None None None 119355874 Common - hypothetical protein Cpha266_0021 3 None None None 119357263 Nonpathogen - hypothetical protein Cpha266_1455 4 None None None 119357517 Common - thioredoxin Cpha266_1719 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 119358406 Nonpathogen - hypothetical protein Cpha266_2642 6 COG4634 COG4634, Uncharacterized protein conserved in bacteria Function unknown 119357004 Common - heat shock protein 90 Cpha266_1188 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 119357010 Common - Kojibiose phosphorylase Cpha266_1194 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 119357403 Common - helicase domain protein Cpha266_1602 118 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 119357171 Nonpathogen - hypothetical protein Cpha266_1360 1 None None None 119356781 Common - recombination factor protein RarA Cpha266_0953 239 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 119356123 Nonpathogen - hypothetical protein Cpha266_0280 1 None None None 119355891 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Cpha266_0041 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 119356876 Common - glycosyl transferase, family 2 Cpha266_1049 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119356466 Common clpX ATP-dependent protease ATP-binding subunit Cpha266_0631 234 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 119356999 Nonpathogen - hypothetical protein Cpha266_1183 7 COG1981 COG1981, Predicted membrane protein Function unknown 119357713 Common - hypoxanthine phosphoribosyltransferase Cpha266_1917 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 119357631 Common - Methyltransferase type 12 Cpha266_1835 33 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 119358216 Common - hypothetical protein Cpha266_2448 28 COG2930 COG2930, Uncharacterized conserved protein Function unknown 119356112 Nonpathogen - hypothetical protein Cpha266_0268 1 None None None 119356395 Common - Phosphoenolpyruvate carboxylase Cpha266_0559 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 119356529 Common - Lipocalin family protein Cpha266_0694 64 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 119356151 Common - outer surface protein, putative Cpha266_0309 7 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 119356865 Common - phosphate binding protein Cpha266_1038 153 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 119356611 Common - ATPase (AAA+ superfamily)-like Cpha266_0779 51 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119358297 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_2529 87 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 119356863 Common - hypothetical protein Cpha266_1036 13 None None None 119358053 Common - hypothetical protein Cpha266_2281 3 None None None 119355945 Common - UspA domain protein Cpha266_0095 66 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119357833 Common - Integrase, catalytic region Cpha266_2041 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356755 Nonpathogen - hypothetical protein Cpha266_0927 3 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 119357365 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Cpha266_1563 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119357550 Nonpathogen - YapH protein Cpha266_1753 7 None None None 119357296 Common - restriction modification system DNA specificity domain Cpha266_1492 85 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 119356601 Common - hypothetical protein Cpha266_0769 2 None None None 119356383 Common - amino acid adenylation domain Cpha266_0546 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119356433 Nonpathogen - hypothetical protein Cpha266_0597 4 None None None 119357854 Common - conserved hypothetical cytosolic protein Cpha266_2062 18 None None None 119357900 Common - hypothetical protein Cpha266_2108 22 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119358324 Common - DNA repair protein RecO Cpha266_2556 38 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 119358256 Common rpmF 50S ribosomal protein L32 Cpha266_2488 68 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 119356573 Common - nitrogenase molybdenum-iron protein beta chain Cpha266_0740 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119357792 Nonpathogen - hypothetical protein Cpha266_1999 8 None None None 119357248 Common - hypothetical protein Cpha266_1440 6 COG1598 COG1598, Uncharacterized conserved protein Function unknown 119355882 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cpha266_0032 85 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 119358065 Common - nicotinate-nucleotide pyrophosphorylase Cpha266_2293 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 119356140 Nonpathogen - hypothetical protein Cpha266_0298 6 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 119356322 Common - cobalt transport protein Cpha266_0485 56 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 119356449 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Cpha266_0613 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 119356018 Nonpathogen - C-type cytochrome, putative Cpha266_0171 5 COG2863 COG2863, Cytochrome c553 Energy production and conversion 119356166 Common - flavodoxin Cpha266_0324 72 COG0716 FldA, Flavodoxins Energy production and conversion 119357013 Common - thioredoxin reductase Cpha266_1197 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 119356773 Common - DoxX family protein Cpha266_0945 56 COG2259 COG2259, Predicted membrane protein Function unknown 119358358 Common - glycerol kinase Cpha266_2590 180 COG0554 GlpK, Glycerol kinase Energy production and conversion 119356901 Common - anti-sigma-factor antagonist Cpha266_1080 11 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 119357905 Common - transposase IS3/IS911 family protein Cpha266_2113 37 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357663 Common - major facilitator superfamily MFS_1 Cpha266_1867 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119358036 Common - HipA domain protein Cpha266_2264 59 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 119356300 Common - redox-active disulfide protein 2 Cpha266_0462 67 None None None 119357579 Common - ribonucleotide-diphosphate reductase subunit alpha Cpha266_1782 169 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 119357353 Common - hypothetical protein Cpha266_1551 27 None None None 119356312 Common - DNA ligase, NAD-dependent Cpha266_0475 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 119356071 Nonpathogen - Septum formation initiator Cpha266_0224 3 None None None 119357234 Common - hypothetical protein Cpha266_1426 11 None None None 119356187 Nonpathogen - hypothetical protein Cpha266_0348 1 None None None 119356825 Common - Adenosylcobinamide kinase Cpha266_0998 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 119357201 Common - protein of unknown function DUF1568 Cpha266_1392 48 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358115 Common - polysaccharide export protein Cpha266_2347 58 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 119357826 Common - stationary-phase survival protein SurE Cpha266_2034 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 119357611 Nonpathogen - hypothetical protein Cpha266_1815 2 None None None 119358183 Nonpathogen - 50S ribosomal protein L29 Cpha266_2415 3 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 119356319 Common - protein of unknown function DUF88 Cpha266_0482 60 COG1432 COG1432, Uncharacterized conserved protein Function unknown 119356442 Common - TonB family protein Cpha266_0606 28 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 119358343 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family Cpha266_2575 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 119356343 Common - peptidase M50 Cpha266_0506 38 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 119356498 Common - protein of unknown function DUF140 Cpha266_0663 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 119357732 Common groEL chaperonin GroEL Cpha266_1936 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 119357208 Common - putative transcriptional regulator Cpha266_1399 74 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119357220 Common - tRNA/rRNA methyltransferase (SpoU) Cpha266_1411 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 119357067 Common - peptidase C14, caspase catalytic subunit p20 Cpha266_1254 23 None None None 119356479 Common - protein of unknown function DUF81 Cpha266_0644 10 COG0730 COG0730, Predicted permeases General function prediction only 119356115 Nonpathogen - hypothetical protein Cpha266_0271 1 None None None 119356371 Common - hypothetical protein Cpha266_0534 9 None None None 119357742 Nonpathogen - hypothetical protein Cpha266_1948 1 None None None 119355867 Common - Rhodopirellula transposase family protein Cpha266_0013 9 None None None 119355927 Common - IstB domain protein ATP-binding protein Cpha266_0077 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356361 Common - hypothetical protein Cpha266_0524 14 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 119356666 Common - pantothenate kinase Cpha266_0835 135 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 119356235 Common - hypothetical protein Cpha266_0396 16 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 119356684 Common - acetolactate synthase, large subunit, biosynthetic type Cpha266_0853 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 119356378 Common - bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase Cpha266_0541 191 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 119358481 Common - cell division protein FtsA Cpha266_2717 176 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 119356177 Nonpathogen - hypothetical protein Cpha266_0338 10 COG1833 COG1833, Uncharacterized conserved protein Function unknown 119356882 Common - IstB domain protein ATP-binding protein Cpha266_1057 93 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357703 Common - imidazoleglycerol phosphate synthase, cyclase subunit Cpha266_1907 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 119356052 Common - Uncharacterised conserved protein UCP016719 Cpha266_0205 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 119356094 Common - HipA domain protein Cpha266_0247 64 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 119357223 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Cpha266_1414 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119358331 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_2563 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 119356102 Common - integron integrase Cpha266_0257 218 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119356971 Nonpathogen - hypothetical protein Cpha266_1154 1 None None None 119356555 Common - hydrogenase accessory protein HypB Cpha266_0721 143 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 119358013 Common - protein of unknown function DUF1568 Cpha266_2237 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358276 Nonpathogen - hypothetical protein Cpha266_2508 8 None None None 119357987 Common - hypothetical protein Cpha266_2207 10 None None None 119358263 Common - Ribonuclease III Cpha266_2495 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 119358392 Common - transposase Cpha266_2625 17 None None None 119356190 Common - glycosyl transferase, family 2 Cpha266_0351 180 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119356309 Nonpathogen - hypothetical protein Cpha266_0472 1 None None None 119357628 Common - sigma54 specific transcriptional regulator, Fis family Cpha266_1832 174 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 119356741 Common - sulfate transporter Cpha266_0913 166 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 119357384 Nonpathogen - hypothetical protein Cpha266_1582 1 None None None 119356946 Common - DEAD/DEAH box helicase domain protein Cpha266_1126 228 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 119358362 Common - NusG antitermination factor Cpha266_2594 76 COG0250 NusG, Transcription antiterminator Transcription 119357529 Common - protein of unknown function DUF456 Cpha266_1732 15 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 119358241 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Cpha266_2473 94 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 119357764 Common - amino acid-binding ACT domain protein Cpha266_1971 38 COG4747 COG4747, ACT domain-containing protein General function prediction only 119357993 Common - RNA-directed DNA polymerase (Reverse transcriptase) Cpha266_2214 93 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 119358347 Common - putative phosphohistidine phosphatase, SixA Cpha266_2579 68 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 119357845 Nonpathogen - hypothetical protein Cpha266_2053 3 COG4006 COG4006, Uncharacterized protein conserved in archaea Function unknown 119356892 Common - hypothetical protein Cpha266_1071 5 None None None 119357599 Nonpathogen - amine oxidase Cpha266_1802 1 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 119358122 Common - putative cold-shock DNA-binding domain protein Cpha266_2354 177 COG1278 CspC, Cold shock proteins Transcription 119358038 Common - short-chain dehydrogenase/reductase SDR Cpha266_2266 214 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119357095 Common - putative DNA-binding protein Cpha266_1282 40 COG2944 COG2944, Predicted transcriptional regulator Transcription 119357675 Nonpathogen - hypothetical protein Cpha266_1879 1 None None None 119356352 Common - hypothetical protein Cpha266_0515 23 COG3179 COG3179, Predicted chitinase General function prediction only 119357670 Common - heat-inducible transcription repressor HrcA Cpha266_1874 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 119357268 Common - protein of unknown function DUF255 Cpha266_1460 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 119357055 Common - protein of unknown function DUF214 Cpha266_1242 29 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119357287 Common - RNA-directed DNA polymerase (Reverse transcriptase) Cpha266_1481 90 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 119357600 Nonpathogen - hypothetical protein Cpha266_1803 1 None None None 119356054 Nonpathogen - bacteriochlorophyll C binding protein Cpha266_0207 3 None None None 119358454 Nonpathogen - hypothetical protein Cpha266_2690 2 None None None 119357473 Common - hypothetical protein Cpha266_1672 6 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 119357989 Common - hypothetical protein Cpha266_2209 13 None None None 119357213 Common - conserved hypothetical protein 341 Cpha266_1404 55 COG1808 COG1808, Predicted membrane protein Function unknown 119356878 Nonpathogen - hypothetical protein Cpha266_1051 2 None None None 119357881 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase Cpha266_2089 211 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 119356277 Common - TOBE domain protein Cpha266_0439 10 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 119356550 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_0716 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357255 Nonpathogen - hypothetical protein Cpha266_1447 1 None None None 119358307 Common - hypothetical protein Cpha266_2539 7 None None None 119356007 Common - TPR repeat-containing protein Cpha266_0160 17 COG4125 COG4125, Predicted membrane protein Function unknown 119358258 Common - 3-oxoacyl-(acyl carrier protein) synthase III Cpha266_2490 215 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 119355869 Common - transposase, IS4 family protein Cpha266_0015 21 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 119355928 Common - hypothetical protein Cpha266_0078 2 None None None 119356175 Common - thiamine-monophosphate kinase Cpha266_0336 200 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 119355981 Nonpathogen - hypothetical protein Cpha266_0131 4 None None None 119356067 Nonpathogen - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0220 6 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 119357416 Common - restriction endonuclease Cpha266_1615 39 COG1715 Mrr, Restriction endonuclease Defense mechanisms 119357435 Nonpathogen - conserved hypothetical protein-signal peptide prediction Cpha266_1634 7 None None None 119356631 Common - cell shape determining protein, MreB/Mrl family Cpha266_0800 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 119358239 Nonpathogen - hypothetical protein Cpha266_2471 3 None None None 119358328 Nonpathogen - hypothetical protein Cpha266_2560 3 None None None 119355990 Common - Polysulphide reductase, NrfD Cpha266_0140 43 COG5557 COG5557, Polysulphide reductase Energy production and conversion 119357859 Nonpathogen - hypothetical protein Cpha266_2067 1 None None None 119356715 Nonpathogen - hypothetical protein Cpha266_0887 1 None None None 119356156 Common - ferric uptake regulator, Fur family Cpha266_0314 199 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 119357088 Common - NAD-dependent epimerase/dehydratase Cpha266_1275 33 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119357868 Nonpathogen - Sporulation domain protein Cpha266_2076 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 119356034 Nonpathogen - hypothetical protein Cpha266_0187 3 None None None 119356645 Common - tyrosyl-tRNA synthetase Cpha266_0814 243 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119358468 Common - putative lipoprotein Cpha266_2704 7 COG4105 ComL, DNA uptake lipoprotein General function prediction only 119357343 Common - adenylate kinases Cpha266_1541 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 119357604 Common - hypothetical protein Cpha266_1807 6 None None None 119355880 Common - sulfur oxidation protein SoxZ Cpha266_0030 33 None None None 119357462 Nonpathogen - hypothetical protein Cpha266_1661 1 None None None 119358431 Common - Uncharacterised conserved protein UCP033563 Cpha266_2667 50 COG4198 COG4198, Uncharacterized conserved protein Function unknown 119357181 Nonpathogen - Ion transport 2 domain protein Cpha266_1372 1 None None None 119356491 Common - putative virulence protein Cpha266_0656 59 COG3943 COG3943, Virulence protein General function prediction only 119356262 Common - histone family protein DNA-binding protein Cpha266_0424 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 119355942 Common - virulence associated protein B Cpha266_0092 15 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 119357061 Common - arsenite-activated ATPase ArsA Cpha266_1248 97 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 119358429 Common - peptidase M22, glycoprotease Cpha266_2665 89 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 119358099 Nonpathogen - hypothetical protein Cpha266_2329 2 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 119357383 Nonpathogen - hypothetical protein Cpha266_1581 1 None None None 119357801 Common tsf elongation factor Ts Cpha266_2009 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 119357301 Nonpathogen - hypothetical protein Cpha266_1499 2 None None None 119356817 Nonpathogen - hypothetical protein Cpha266_0990 3 None None None 119358078 Common - 8-amino-7-oxononanoate synthase Cpha266_2306 191 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 119357189 Common - transcriptional modulator of MazE/toxin, MazF Cpha266_1380 52 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 119356998 Common - Inorganic diphosphatase Cpha266_1182 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 119357100 Nonpathogen - hypothetical protein Cpha266_1287 2 None None None 119357166 Nonpathogen - hypothetical protein Cpha266_1355 1 None None None 119358079 Common - IstB domain protein ATP-binding protein Cpha266_2308 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119358287 Common - electron transfer flavoprotein beta-subunit Cpha266_2519 151 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 119356903 Common - maf protein Cpha266_1082 184 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 119356403 Common - extracellular solute-binding protein, family 5 Cpha266_0567 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119356763 Common - hypothetical protein Cpha266_0935 2 None None None 119356961 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cpha266_1144 200 COG0546 Gph, Predicted phosphatases General function prediction only 119357822 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Cpha266_2030 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119357684 Nonpathogen - bacteriochlorophyll A protein Cpha266_1888 3 None None None 119358133 Common - short-chain dehydrogenase/reductase SDR Cpha266_2365 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119356729 Nonpathogen - HRDC Cpha266_0901 1 None None None 119356408 Common - RNA methyltransferase, TrmH family, group 3 Cpha266_0572 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 119356597 Common - NADH:flavin oxidoreductase/NADH oxidase Cpha266_0765 204 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 119357453 Common - DNA polymerase III, subunits gamma and tau Cpha266_1652 245 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 119356851 Nonpathogen - hypothetical protein Cpha266_1024 3 None None None 119358232 Common - cytochrome c, class I Cpha266_2464 43 COG3245 CycB, Cytochrome c5 Energy production and conversion 119357501 Nonpathogen - hypothetical protein Cpha266_1703 1 None None None 119356730 Common - protein of unknown function DUF323 Cpha266_0902 118 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119356795 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Cpha266_0967 112 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 119358461 Common - rare lipoprotein A Cpha266_2697 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 119356841 Common - aminotransferase, class I and II Cpha266_1014 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119356270 Nonpathogen - hypothetical protein Cpha266_0432 3 None None None 119355952 Common - succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family Cpha266_0102 28 None None None 119357155 Common - NLP/P60 protein Cpha266_1344 142 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119357315 Common - iron-containing alcohol dehydrogenase Cpha266_1513 169 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 119356721 Common - pentapeptide repeat protein Cpha266_0893 80 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 119357359 Common - Integrase, catalytic region Cpha266_1557 77 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358112 Common - ABC transporter related Cpha266_2344 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119357329 Common - hypothetical protein Cpha266_1527 12 None None None 119357044 Common - hypothetical protein Cpha266_1230 20 None None None 119357515 Common - Curli production assembly/transport component CsgG Cpha266_1717 14 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 119357038 Common - hypothetical protein Cpha266_1224 9 COG2253 COG2253, Uncharacterized conserved protein Function unknown 119357467 Common - efflux transporter, RND family, MFP subunit Cpha266_1666 176 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119356532 Common - ABC transporter, transmembrane region, type 1 Cpha266_0697 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 119357699 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Cpha266_1903 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 119356181 Common - replicative DNA helicase Cpha266_0342 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 119356484 Common - protein of unknown function DUF891 Cpha266_0649 13 COG4679 COG4679, Phage-related protein Function unknown 119355973 Common - hypothetical protein Cpha266_0123 43 COG2210 COG2210, Uncharacterized conserved protein Function unknown 119356253 Common - glutamate racemase Cpha266_0415 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 119358410 Common - hypothetical protein Cpha266_2646 14 None None None 119356987 Common - Transketolase, central region Cpha266_1170 229 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 119357250 Common - hypothetical protein Cpha266_1442 3 None None None 119356426 Common - protein of unknown function DUF214 Cpha266_0590 141 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119357566 Common - tyrosine recombinase XerD Cpha266_1769 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119358134 Common - helix-turn-helix domain protein Cpha266_2366 17 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 119356708 Common - two component transcriptional regulator, winged helix family Cpha266_0880 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119355939 Common - putative hypothetical Gifsy-1 prophage protein Cpha266_0089 9 None None None 119357192 Common - hypothetical protein Cpha266_1383 4 None None None 119356822 Common - membrane protein of unknown function Cpha266_0995 74 COG1950 COG1950, Predicted membrane protein Function unknown 119356381 Common - TspO and MBR like proteins Cpha266_0544 62 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 119357441 Common - beta-phosphoglucomutase family hydrolase Cpha266_1640 108 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 119357105 Common - hypothetical protein Cpha266_1292 4 None None None 119357596 Common - histidinol-phosphate phosphatase, putative Cpha266_1799 199 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 119357877 Common - hypothetical protein Cpha266_2085 69 COG1432 COG1432, Uncharacterized conserved protein Function unknown 119356290 Common - molybdate ABC transporter, ATPase subunit Cpha266_0452 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 119357049 Common - zinc finger, SWIM domain protein Cpha266_1236 40 COG4279 COG4279, Uncharacterized conserved protein Function unknown 119358098 Common - ATPase, BadF/BadG/BcrA/BcrD type Cpha266_2328 54 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 119356436 Common - GTP cyclohydrolase II Cpha266_0600 230 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 119357936 Common - 6-phosphogluconate dehydrogenase-like protein Cpha266_2151 187 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 119357726 Nonpathogen - cyclase/dehydrase Cpha266_1930 13 None None None 119356939 Common - cobalamin biosynthesis protein CobD Cpha266_1119 146 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 119356624 Common - CheB methylesterase Cpha266_0793 135 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 119358167 Common rpsM 30S ribosomal protein S13 Cpha266_2399 221 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 119357469 Common - protein of unknown function DUF214 Cpha266_1668 210 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 119356333 Common - Sua5/YciO/YrdC/YwlC family protein Cpha266_0496 236 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 119358221 Common - hypothetical protein Cpha266_2453 4 None None None 119355903 Common - ATP-dependent DNA helicase RecQ Cpha266_0053 227 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 119355930 Common - DNA-cytosine methyltransferase Cpha266_0080 112 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 119356388 Common - polynucleotide phosphorylase/polyadenylase Cpha266_0552 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 119357923 Nonpathogen - hypothetical protein Cpha266_2138 5 None None None 119358155 Common - light-independent protochlorophyllide reductase subunit B Cpha266_2387 40 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119356513 Common - arsenite-activated ATPase ArsA Cpha266_0678 87 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 119355896 Common - ATP-dependent Clp protease adaptor protein ClpS Cpha266_0046 5 COG2127 COG2127, Uncharacterized conserved protein Function unknown 119356701 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_0872 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356925 Nonpathogen - hypothetical protein Cpha266_1104 3 None None None 119357958 Common - IstB domain protein ATP-binding protein Cpha266_2173 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357075 Common - large conductance mechanosensitive channel protein Cpha266_1262 125 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 119358016 Common - IstB domain protein ATP-binding protein Cpha266_2240 95 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356478 Common - IstB domain protein ATP-binding protein Cpha266_0643 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357145 Common - 5-formyltetrahydrofolate cyclo-ligase Cpha266_1334 132 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 119357963 Nonpathogen - hypothetical protein Cpha266_2179 4 None None None 119355959 Common - DNA topoisomerase I Cpha266_0109 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 119357778 Nonpathogen - hypothetical protein Cpha266_1985 1 None None None 119358160 Common cysS cysteinyl-tRNA synthetase Cpha266_2392 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119356516 Common - hypothetical protein Cpha266_0681 25 None None None 119357131 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Cpha266_1320 215 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 119358408 Nonpathogen - hypothetical protein Cpha266_2644 4 None None None 119357965 Nonpathogen - hypothetical protein Cpha266_2182 10 None None None 119356792 Common - NADH dehydrogenase (ubiquinone) Cpha266_0964 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 119358103 Nonpathogen - glycosyl transferase, group 1 Cpha266_2333 7 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357119 Common - prolipoprotein diacylglyceryl transferase Cpha266_1308 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 119358401 Common - hypothetical protein Cpha266_2637 5 None None None 119357393 Nonpathogen - hypothetical protein Cpha266_1592 1 None None None 119358491 Common - Peptidoglycan glycosyltransferase Cpha266_2727 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 119357481 Common - aminoacyl-histidine dipeptidase Cpha266_1680 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 119357406 Nonpathogen - hypothetical protein Cpha266_1605 2 None None None 119357058 Nonpathogen - hypothetical protein Cpha266_1245 5 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 119358177 Common rpsH 30S ribosomal protein S8 Cpha266_2409 214 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 119356936 Common - cob(II)yrinic acid a,c-diamide reductase Cpha266_1116 117 COG0778 NfnB, Nitroreductase Energy production and conversion 119357522 Common rpmG 50S ribosomal protein L33 Cpha266_1725 5 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 119355858 Common - chromosomal replication initiator protein DnaA Cpha266_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 119358387 Common - hypothetical protein Cpha266_2620 58 None None None 119357496 Common - Integrase, catalytic region Cpha266_1698 124 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356515 Common - isocitrate dehydrogenase, NADP-dependent Cpha266_0680 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 119357101 Nonpathogen - hypothetical protein Cpha266_1288 1 None None None 119357326 Common rpsP 30S ribosomal protein S16 Cpha266_1524 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 119356725 Nonpathogen - hypothetical protein Cpha266_0897 1 None None None 119356314 Nonpathogen - hypothetical protein Cpha266_0477 1 COG5652 COG5652, Predicted integral membrane protein Function unknown 119356110 Nonpathogen - hypothetical protein Cpha266_0266 1 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 119356500 Common - putative undecaprenol kinase Cpha266_0665 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 119357336 Common - UDP-glucose 6-dehydrogenase Cpha266_1534 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 119358100 Common - Capsule polysaccharide biosynthesis Cpha266_2330 31 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119357116 Common - Legionella vir region protein Cpha266_1305 5 None None None 119358081 Common - TonB-dependent receptor Cpha266_2310 121 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119356101 Common - protein of unknown function DUF1568 Cpha266_0255 39 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356506 Common - 1-deoxy-D-xylulose-5-phosphate synthase Cpha266_0671 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 119357940 Common - glycosyl transferase, group 1 Cpha266_2155 174 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119356761 Common - outer membrane autotransporter barrel domain Cpha266_0933 32 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 119356594 Common - short-chain dehydrogenase/reductase SDR Cpha266_0762 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 119356202 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cpha266_0363 134 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 119356689 Common - transcriptional regulator, Fis family Cpha266_0858 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 119356682 Common - ketol-acid reductoisomerase Cpha266_0851 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 119356702 Common - amine oxidase Cpha266_0874 111 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119357953 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Cpha266_2168 50 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 119356261 Common - adenine phosphoribosyltransferase Cpha266_0423 165 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 119357955 Nonpathogen - hypothetical protein Cpha266_2170 1 None None None 119355985 Nonpathogen - hypothetical protein Cpha266_0135 6 None None None 119356527 Common - formyltetrahydrofolate deformylase Cpha266_0692 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 119355974 Common - Rhodanese domain protein Cpha266_0124 100 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119358128 Common - bacteriochlorophyll c synthase Cpha266_2360 94 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 119358152 Common - Integrase, catalytic region Cpha266_2384 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119355943 Common - drug resistance transporter, EmrB/QacA subfamily Cpha266_0093 202 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119357144 Common - polyphosphate kinase Cpha266_1333 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 119358496 Common - Chorismate mutase Cpha266_2732 19 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 119356510 Common - hypothetical protein Cpha266_0675 23 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 119357163 Common - hypothetical protein Cpha266_1352 4 None None None 119356603 Nonpathogen - hypothetical protein Cpha266_0771 1 None None None 119357438 Common - alpha/beta hydrolase fold Cpha266_1637 186 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119356481 Common - hypothetical protein Cpha266_0646 16 None None None 119357573 Common - Integral membrane protein TerC Cpha266_1776 141 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 119357976 Common - transposase IS116/IS110/IS902 family protein Cpha266_2194 39 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357844 Nonpathogen - hypothetical protein Cpha266_2052 7 None None None 119358428 Common - iojap-like protein Cpha266_2664 184 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 119358162 Common gidB glucose-inhibited division protein B Cpha266_2394 149 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 119356537 Common - purine nucleoside phosphorylase Cpha266_0702 149 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 119357191 Nonpathogen - protein of unknown function DUF132 Cpha266_1382 2 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119356632 Common - Histidinol dehydrogenase Cpha266_0801 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 119357697 Common - Porphyromonas-type peptidyl-arginine deiminase Cpha266_1901 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 119357121 Common - ABC transporter related Cpha266_1310 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119357443 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Cpha266_1642 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 119357725 Common - thioesterase superfamily protein Cpha266_1929 36 COG0824 FcbC, Predicted thioesterase General function prediction only 119356424 Common - branched-chain amino acid aminotransferase Cpha266_0588 220 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 119355968 Common - protein of unknown function DUF1458 Cpha266_0118 48 COG3360 COG3360, Uncharacterized conserved protein Function unknown 119356564 Common thiG thiazole synthase Cpha266_0730 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 119357961 Common - death-on-curing family protein Cpha266_2176 63 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 119358306 Common - peptide chain release factor 2 Cpha266_2538 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 119358132 Common - cysteine synthase A Cpha266_2364 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 119358254 Common - Excinuclease ABC, C subunit domain protein Cpha266_2486 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119357104 Common - hypothetical protein Cpha266_1291 3 None None None 119356714 Nonpathogen - hypothetical protein Cpha266_0886 1 None None None 119355998 Common - cytochrome c, class I Cpha266_0148 35 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 119356964 Nonpathogen - hypothetical protein Cpha266_1147 1 None None None 119356476 Common - putative transcriptional regulator Cpha266_0641 50 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119356183 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Cpha266_0344 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 119358433 Common - TPR repeat-containing protein Cpha266_2669 47 None None None 119357178 Nonpathogen - hypothetical protein Cpha266_1369 1 None None None 119357454 Common - putative ribonuclease BN Cpha266_1653 129 COG1295 Rbn, Predicted membrane protein Function unknown 119356287 Common - hypothetical protein Cpha266_0449 10 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119357461 Common - hypothetical protein Cpha266_1660 15 None None None 119357415 Common - restriction endonuclease Cpha266_1614 38 COG1715 Mrr, Restriction endonuclease Defense mechanisms 119357563 Common - homoserine O-acetyltransferase Cpha266_1766 132 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 119356933 Common - periplasmic binding protein Cpha266_1112 162 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119356257 Common era GTP-binding protein Era Cpha266_0419 226 COG1159 Era, GTPase General function prediction only 119356522 Common - single-stranded-DNA-specific exonuclease RecJ Cpha266_0687 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 119357480 Common - 3-beta hydroxysteroid dehydrogenase/isomerase Cpha266_1679 134 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119357504 Common - putative transcriptional regulator Cpha266_1706 77 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119357052 Nonpathogen - hypothetical protein Cpha266_1239 1 None None None 119357907 Common - ATPase Cpha266_2115 57 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119357947 Nonpathogen - hypothetical protein Cpha266_2162 1 None None None 119356431 Common - metallophosphoesterase Cpha266_0595 7 COG1409 Icc, Predicted phosphohydrolases General function prediction only 119356791 Common - NADH (or F420H2) dehydrogenase, subunit C Cpha266_0963 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 119356046 Nonpathogen - hypothetical protein Cpha266_0199 3 None None None 119356798 Common - proton-translocating NADH-quinone oxidoreductase, chain M Cpha266_0970 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 119356384 Common - 4'-phosphopantetheinyl transferase Cpha266_0547 58 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 119356292 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Cpha266_0454 158 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 119356857 Nonpathogen - hypothetical protein Cpha266_1030 3 None None None 119356331 Common - pseudouridine synthase Cpha266_0494 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 119358290 Common - hypothetical protein Cpha266_2522 7 None None None 119357872 Common - D-tyrosyl-tRNA(Tyr) deacylase Cpha266_2080 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 119357198 Common - plasmid stabilization system Cpha266_1389 18 COG3668 ParE, Plasmid stabilization system protein General function prediction only 119357806 Common - protein of unknown function DUF59 Cpha266_2014 242 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119356090 Common alaS alanyl-tRNA synthetase Cpha266_0243 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119355865 Common - IstB domain protein ATP-binding protein Cpha266_0009 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357099 Common - hypothetical protein Cpha266_1286 7 None None None 119357377 Common - Rhodanese domain protein Cpha266_1575 11 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119358097 Nonpathogen - hypothetical protein Cpha266_2327 1 None None None 119357063 Common - hypothetical protein Cpha266_1250 5 None None None 119357528 Nonpathogen - hypothetical protein Cpha266_1731 1 None None None 119356033 Common - Isoprenylcysteine carboxyl methyltransferase Cpha266_0186 62 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 119358074 Common - oxidoreductase FAD/NAD(P)-binding domain protein Cpha266_2302 92 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 119356078 Common rplJ 50S ribosomal protein L10 Cpha266_0231 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 119355911 Common - putative transmembrane protein Cpha266_0061 2 None None None 119357057 Common - RND efflux system, outer membrane lipoprotein, NodT family Cpha266_1244 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119356805 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Cpha266_0977 84 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 119358361 Common - metallophosphoesterase Cpha266_2593 125 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 119356392 Common - signal peptide peptidase SppA, 36K type Cpha266_0556 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119357762 Common - hypothetical protein Cpha266_1969 5 None None None 119357489 Common - hypothetical protein Cpha266_1688 3 None None None 119358201 Common - hypothetical protein Cpha266_2433 13 None None None 119357082 Nonpathogen - cytochrome c, class I Cpha266_1269 3 COG2863 COG2863, Cytochrome c553 Energy production and conversion 119358149 Nonpathogen - hypothetical protein Cpha266_2381 1 None None None 119357316 Common - acylneuraminate cytidylyltransferase Cpha266_1514 74 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 119355957 Common - FeoA family protein Cpha266_0107 63 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 119358299 Nonpathogen - hypothetical protein Cpha266_2531 1 None None None 119358460 Common - alpha/beta hydrolase fold Cpha266_2696 68 COG1647 COG1647, Esterase/lipase General function prediction only 119358315 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferases Cpha266_2547 204 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 119357609 Common - glycosyl transferase, family 2 Cpha266_1813 88 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119358192 Common rpsJ 30S ribosomal protein S10 Cpha266_2424 245 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 119356303 Common - protein tyrosine phosphatase Cpha266_0465 146 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 119356207 Common nusA transcription elongation factor NusA Cpha266_0368 216 COG0195 NusA, Transcription elongation factor Transcription 119356170 Common - hypothetical protein Cpha266_0331 5 None None None 119356273 Common - short-chain dehydrogenase/reductase SDR Cpha266_0435 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119357266 Common - protein of unknown function DUF134 Cpha266_1458 40 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 119357432 Common - magnesium chelatase ATPase subunit I Cpha266_1631 70 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 119355887 Common - hypothetical protein Cpha266_0037 89 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 119358420 Nonpathogen - hypothetical protein Cpha266_2656 7 None None None 119356161 Common - Fe2+ transport system protein B-like Cpha266_0319 108 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 119357368 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_1566 54 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 119356989 Common - recombination protein RecR Cpha266_1172 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 119358075 Common - single-strand binding protein Cpha266_2303 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 119358289 Common - MscS Mechanosensitive ion channel Cpha266_2521 40 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 119355948 Common - protein of unknown function DUF21 Cpha266_0098 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 119356641 Common nadE NAD synthetase Cpha266_0810 235 COG0171 NadE, NAD synthase Coenzyme metabolism 119356243 Nonpathogen - hypothetical protein Cpha266_0404 3 None None None 119357398 Common - GTPase EngC Cpha266_1597 163 COG1162 COG1162, Predicted GTPases General function prediction only 119357597 Nonpathogen - hypothetical protein Cpha266_1800 1 None None None 119357618 Nonpathogen - glycosyl transferase, group 1 Cpha266_1822 7 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119356982 Common - Methylmalonyl-CoA mutase Cpha266_1165 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 119358139 Common - phosphoribosyltransferase Cpha266_2371 170 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 119355993 Common - Cobyrinic acid a,c-diamide synthase Cpha266_0143 112 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 119357862 Common - aldehyde dehydrogenase Cpha266_2070 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119357672 Nonpathogen - hypothetical protein Cpha266_1876 4 None None None 119357886 Nonpathogen - hypothetical protein Cpha266_2094 3 None None None 119357521 Common - diaminopimelate decarboxylase Cpha266_1724 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 119358323 Common - putative regulatory protein, FmdB family Cpha266_2555 69 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 119357673 Common - prolyl-tRNA synthetase Cpha266_1877 243 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119357646 Nonpathogen - hypothetical protein Cpha266_1850 1 None None None 119358348 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Cpha266_2580 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 119358476 Common - protein of unknown function DUF152 Cpha266_2712 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 119358321 Common - UDP-N-acetylglucosamine 2-epimerase Cpha266_2553 146 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 119357715 Common - transcriptional regulator, NifA subfamily, Fis Family Cpha266_1919 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 119356358 Common - hypothetical protein Cpha266_0521 7 None None None 119357280 Nonpathogen - hypothetical protein Cpha266_1473 2 None None None 119356338 Common - endonuclease III Cpha266_0501 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 119356836 Common - hypothetical protein Cpha266_1009 25 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 119357509 Common dinD DNA-damage-inducible protein D Cpha266_1711 20 None None None 119356775 Common - ErfK/YbiS/YcfS/YnhG family protein Cpha266_0947 36 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119357418 Common - hypothetical protein Cpha266_1617 9 None None None 119357347 Common hslU ATP-dependent protease ATP-binding subunit Cpha266_1545 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 119357090 Common - lipoyl synthase Cpha266_1277 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 119357470 Common - protein of unknown function DUF214 Cpha266_1669 207 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 119358414 Nonpathogen - hypothetical protein Cpha266_2650 6 None None None 119356855 Common - putative PAS/PAC sensor protein Cpha266_1028 39 None None None 119358301 Nonpathogen - hypothetical protein Cpha266_2533 13 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 119357451 Common aspS aspartyl-tRNA synthetase Cpha266_1650 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119357840 Common - CRISPR-associated RAMP protein, Csm3 family Cpha266_2048 33 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 119357246 Common - hypothetical protein Cpha266_1438 47 COG2378 COG2378, Predicted transcriptional regulator Transcription 119356943 Nonpathogen - Xylose isomerase domain protein TIM barrel Cpha266_1123 8 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 119355983 Common - DsrE family protein Cpha266_0133 41 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 119357747 Common - helicase domain protein Cpha266_1953 167 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119356996 Common - polar amino acid ABC transporter, inner membrane subunit Cpha266_1179 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119358062 Common - NAD-dependent epimerase/dehydratase Cpha266_2290 164 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119358393 Common - transposase Cpha266_2626 40 None None None 119357701 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cpha266_1905 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 119356417 Common rnhA ribonuclease H Cpha266_0581 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 119358444 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cpha266_2680 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 119357381 Common - hypothetical protein Cpha266_1579 2 None None None 119358018 Nonpathogen - hypothetical protein Cpha266_2243 2 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356394 Common - Mg chelatase, subunit ChlI Cpha266_0558 192 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 119356076 Common rplK 50S ribosomal protein L11 Cpha266_0229 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 119357224 Common - PhoH family protein Cpha266_1415 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 119356410 Common - glycine dehydrogenase subunit 1 Cpha266_0574 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 119357341 Common - radical SAM enzyme, Cfr family Cpha266_1539 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 119358381 Nonpathogen - hypothetical protein Cpha266_2614 1 None None None 119357424 Nonpathogen - hypothetical protein Cpha266_1623 1 None None None 119356493 Common - domain of unknown function DUF1730 Cpha266_0658 132 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 119356976 Common - peptidase, membrane zinc metallopeptidase, putative Cpha266_1159 38 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 119357795 Common - aldolase Cpha266_2002 66 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 119356196 Common - glycosyl transferase, group 1 Cpha266_0357 181 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357755 Common - ribonuclease R Cpha266_1962 192 COG0557 VacB, Exoribonuclease R Transcription 119357229 Common - Lysine exporter protein (LYSE/YGGA) Cpha266_1421 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119356965 Common - hypothetical protein Cpha266_1148 4 COG1733 COG1733, Predicted transcriptional regulators Transcription 119357919 Common - transposase and inactivated derivatives Cpha266_2134 42 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356134 Common - nucleotidyltransferase substrate binding protein, HI0074 family Cpha266_0291 29 None None None 119356579 Common - S-adenosylmethionine synthetase Cpha266_0746 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 119356780 Common - riboflavin synthase subunit alpha Cpha266_0952 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 119357695 Common rpmA 50S ribosomal protein L27 Cpha266_1899 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 119356920 Common - 3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III C-terminal domain protein Cpha266_1099 8 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 119358248 Common - Excinuclease ABC, C subunit domain protein Cpha266_2480 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119356367 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Cpha266_0530 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 119357293 Common - regulatory protein, ArsR Cpha266_1489 4 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119357216 Common - plasmid maintenance system antidote protein, XRE family Cpha266_1407 71 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 119358046 Common - metal dependent phosphohydrolase Cpha266_2274 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 119356656 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Cpha266_0825 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 119356099 Nonpathogen - putative addiction module component, TIGR02574 family Cpha266_0253 5 None None None 119357626 Common - Undecaprenyl-phosphate galactose phosphotransferase Cpha266_1830 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 119356845 Common - DedA family protein Cpha266_1018 77 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 119357074 Common - CoB--CoM heterodisulfide reductase Cpha266_1261 58 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 119356540 Nonpathogen - Tetratricopeptide TPR_2 repeat protein Cpha266_0705 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 119356056 Common - pentapeptide repeat protein Cpha266_0209 102 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 119356191 Common - transposase, IS4 family protein Cpha266_0352 18 None None None 119358353 Common prmA ribosomal protein L11 methyltransferase Cpha266_2585 173 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 119356717 Common - polysaccharide biosynthesis protein Cpha266_0889 23 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 119356742 Common - yecA family protein Cpha266_0914 20 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 119356815 Common - Trans-hexaprenyltranstransferase Cpha266_0988 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 119356141 Common - DNA helicase Cpha266_0299 104 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 119358199 Common - PEBP family protein Cpha266_2431 92 COG1881 COG1881, Phospholipid-binding protein General function prediction only 119358113 Common - ABC-2 type transporter Cpha266_2345 30 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119356871 Common - efflux transporter, RND family, MFP subunit Cpha266_1044 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119357901 Common - Methyltransferase type 11 Cpha266_2109 131 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119356662 Common - putative transcriptional regulator, AsnC family Cpha266_0831 157 COG1522 Lrp, Transcriptional regulators Transcription 119356789 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Cpha266_0961 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 119355889 Nonpathogen - hypothetical protein Cpha266_0039 1 None None None 119357477 Common - binding-protein-dependent transport systems inner membrane component Cpha266_1676 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119358280 Common rpsF 30S ribosomal protein S6 Cpha266_2512 138 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 119358054 Common - Legionella vir region protein Cpha266_2282 4 None None None 119357182 Nonpathogen - hypothetical protein Cpha266_1373 1 None None None 119355925 Nonpathogen - hypothetical protein Cpha266_0075 1 None None None 119356576 Common - nitrogen regulatory protein P-II Cpha266_0743 179 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 119356692 Common - OmpA/MotB domain protein Cpha266_0861 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119357012 Common - thioredoxin Cpha266_1196 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 119356013 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0166 21 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 119357851 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cpha266_2059 25 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 119356245 Nonpathogen - hypothetical protein Cpha266_0406 1 None None None 119357475 Common - ribose-phosphate pyrophosphokinase Cpha266_1674 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 119357363 Common - HI0933 family protein Cpha266_1561 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 119357914 Common - Methyltransferase type 11 Cpha266_2127 96 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119355918 Common - protein of unknown function DUF323 Cpha266_0068 79 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119357595 Nonpathogen - hypothetical protein Cpha266_1798 2 None None None 119357348 Common - ATP-dependent protease peptidase subunit Cpha266_1546 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 119356629 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Cpha266_0798 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119358190 Common rplD 50S ribosomal protein L4 Cpha266_2422 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 119356736 Nonpathogen - hypothetical protein Cpha266_0908 5 None None None 119357356 Nonpathogen - hypothetical protein Cpha266_1554 1 None None None 119357015 Common - hypothetical protein Cpha266_1199 4 None None None 119357577 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Cpha266_1780 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 119357857 Common - hypothetical protein Cpha266_2065 4 None None None 119356168 Common - Integrase, catalytic region Cpha266_0328 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358069 Common - arsenite-activated ATPase ArsA Cpha266_2297 92 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 119356144 Common - alpha/beta hydrolase fold Cpha266_0302 86 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119356219 Common - hypothetical protein Cpha266_0380 4 None None None 119357261 Nonpathogen - glycosyl transferase Cpha266_1453 3 None None None 119356327 Common - ferredoxin--NADP(+) reductase subunit alpha Cpha266_0490 98 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 119358179 Common rplE 50S ribosomal protein L5 Cpha266_2411 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 119357921 Common - Metal-dependent hydrolases of the beta-lactamase superfamily III-like Cpha266_2136 18 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 119357023 Nonpathogen - hypothetical protein Cpha266_1208 1 None None None 119356454 Common - ABC transporter related Cpha266_0618 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 119357832 Common - protein tyrosine phosphatase Cpha266_2040 124 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 119356225 Common - protein of unknown function DUF214 Cpha266_0386 129 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119358223 Common - ATPase associated with various cellular activities, AAA_3 Cpha266_2455 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 119356862 Nonpathogen - hypothetical protein Cpha266_1035 3 None None None 119356009 Common - hypothetical protein Cpha266_0162 37 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 119356671 Common - WD-40 repeat protein Cpha266_0840 88 COG2319 COG2319, FOG: WD40 repeat General function prediction only 119356308 Common - protein of unknown function UPF0153 Cpha266_0471 13 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 119356060 Common - arsenite-activated ATPase ArsA Cpha266_0213 97 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 119356927 Common - Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ Cpha266_1106 183 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 119358422 Common - Integrase, catalytic region Cpha266_2658 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357784 Common ileS isoleucyl-tRNA synthetase Cpha266_1991 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119358264 Common - glycine dehydrogenase subunit 2 Cpha266_2496 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 119356757 Common hisB imidazoleglycerol-phosphate dehydratase Cpha266_0929 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 119358089 Common - glycosyl transferase, group 1 Cpha266_2318 87 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119357036 Common - superfamily I DNA and RNA helicase and helicase subunit Cpha266_1222 88 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 119356268 Common - Cytochrome b/b6, N-terminal domain Cpha266_0430 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 119356951 Common - restriction modification system DNA specificity domain Cpha266_1131 37 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 119357986 Common - protein of unknown function DUF1568 Cpha266_2205 46 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357771 Common - phosphoribosylglycinamide formyltransferase Cpha266_1978 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 119356618 Common - putative DNA-binding protein Cpha266_0786 41 COG2944 COG2944, Predicted transcriptional regulator Transcription 119356234 Common - protein of unknown function DUF151 Cpha266_0395 77 COG1259 COG1259, Uncharacterized conserved protein Function unknown 119356802 Common - Ni/Fe-hydrogenase, b-type cytochrome subunit Cpha266_0974 55 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 119358028 Common - hypothetical protein Cpha266_2256 12 None None None 119358004 Common - transposase IS116/IS110/IS902 family protein Cpha266_2226 54 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357079 Common secA preprotein translocase subunit SecA Cpha266_1266 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 119358218 Nonpathogen - hypothetical protein Cpha266_2450 3 None None None 119357584 Common - PAS/PAC sensor hybrid histidine kinase Cpha266_1787 226 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119355873 Nonpathogen - hypothetical protein Cpha266_0020 1 None None None 119356669 Common - helicase, RecD/TraA family Cpha266_0838 155 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 119358009 Common - hypothetical protein Cpha266_2232 7 None None None 119355904 Nonpathogen - hypothetical protein Cpha266_0054 1 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 119356464 Common gltD glutamate synthase subunit beta Cpha266_0629 188 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 119356429 Common - dihydroorotate dehydrogenase family protein Cpha266_0593 189 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 119357230 Nonpathogen - hypothetical protein Cpha266_1422 1 None None None 119357275 Nonpathogen - hypothetical protein Cpha266_1467 1 None None None 119358252 Common - Excinuclease ABC, C subunit domain protein Cpha266_2484 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119356545 Common - excinuclease ABC, C subunit Cpha266_0710 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 119356881 Common - protein of unknown function DUF159 Cpha266_1054 111 COG2135 COG2135, Uncharacterized conserved protein Function unknown 119358333 Common - hypothetical protein Cpha266_2565 5 None None None 119356285 Common - Methyltransferase type 11 Cpha266_0447 47 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119356316 Common - Phosphoribosyl-AMP cyclohydrolase Cpha266_0479 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 119357233 Common - protein of unknown function DUF1568 Cpha266_1425 48 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357408 Common - hypothetical protein Cpha266_1607 9 None None None 119358339 Common pyrE orotate phosphoribosyltransferase Cpha266_2571 149 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 119358171 Common secY preprotein translocase subunit SecY Cpha266_2403 228 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 119357534 Common - GTP-binding protein, HSR1-related Cpha266_1737 214 COG2262 HflX, GTPases General function prediction only 119357005 Common - protein of unknown function DUF125, transmembrane Cpha266_1189 37 COG1814 COG1814, Uncharacterized membrane protein Function unknown 119357991 Common - Integrase, catalytic region Cpha266_2211 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357087 Nonpathogen - hypothetical protein Cpha266_1274 4 None None None 119356210 Common - tRNA pseudouridine synthase B Cpha266_0371 232 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 119358388 Nonpathogen - hypothetical protein Cpha266_2621 1 None None None 119357738 Common - hypothetical protein Cpha266_1942 44 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 119357137 Common - pentapeptide repeat protein Cpha266_1326 82 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 119356150 Common - beta-lactamase domain protein Cpha266_0308 59 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 119357126 Common - Rubredoxin-type Fe(Cys)4 protein Cpha266_1315 116 COG1773 COG1773, Rubredoxin Energy production and conversion 119357635 Common - hypothetical protein Cpha266_1839 8 None None None 119356838 Common metG methionyl-tRNA synthetase Cpha266_1011 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119357445 Common - Radical SAM domain protein Cpha266_1644 101 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119356069 Common - elongation factor G Cpha266_0222 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 119358498 Common pgk phosphoglycerate kinase Cpha266_2734 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 119358143 Common - putative oxygen-independent coproporphyrinogen III oxidase Cpha266_2375 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 119358489 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Cpha266_2725 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 119357733 Common groES co-chaperonin GroES Cpha266_1937 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 119356340 Common - Haloacid dehalogenase domain protein hydrolase Cpha266_0503 33 COG0546 Gph, Predicted phosphatases General function prediction only 119356137 Nonpathogen - hypothetical protein Cpha266_0295 1 None None None 119357883 Common - naphthoate synthase Cpha266_2091 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 119355963 Common - 8-amino-7-oxononanoate synthase Cpha266_0113 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 119357299 Common - type III restriction enzyme, res subunit Cpha266_1495 113 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 119358374 Common - acyltransferase 3 Cpha266_2606 100 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 119358506 Nonpathogen rnpA ribonuclease P Cpha266_2742 4 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 119357587 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Cpha266_1790 14 None None None 119355964 Common - protein of unknown function DUF452 Cpha266_0114 14 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 119357007 Common - hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit Cpha266_1191 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 119358022 Common - protein of unknown function DUF1568 Cpha266_2247 33 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357487 Nonpathogen - hypothetical protein Cpha266_1686 3 None None None 119357571 Common - DEAD/DEAH box helicase domain protein Cpha266_1774 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 119356422 Common - CutA1 divalent ion tolerance protein Cpha266_0586 119 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 119356566 Common - Cystathionine gamma-synthase Cpha266_0732 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 119358244 Common - periplasmic solute binding protein Cpha266_2476 168 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 119357176 Common - transposase family protein Cpha266_1366 32 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356259 Nonpathogen - hypothetical protein Cpha266_0421 3 None None None 119355922 Nonpathogen - hypothetical protein Cpha266_0072 2 None None None 119357838 Nonpathogen - CRISPR-associated RAMP protein, Csm5 family Cpha266_2046 2 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 119357396 Common - alpha/beta hydrolase fold Cpha266_1595 176 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119356266 Common - hydroxyneurosporene synthase Cpha266_0428 6 None None None 119356064 Common - Rubredoxin-type Fe(Cys)4 protein Cpha266_0217 121 COG1773 COG1773, Rubredoxin Energy production and conversion 119358236 Common - molybdenum cofactor synthesis domain Cpha266_2468 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 119355936 Nonpathogen - hypothetical protein Cpha266_0086 5 None None None 119358435 Common - nitrogen regulatory protein P-II Cpha266_2671 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 119357463 Common - D-alanine--D-alanine ligase Cpha266_1662 219 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 119357017 Nonpathogen - hypothetical protein Cpha266_1201 2 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 119357106 Common - hypothetical protein Cpha266_1294 10 None None None 119357391 Nonpathogen - hypothetical protein Cpha266_1590 1 None None None 119357951 Common - hydrogenase/sulfur reductase, beta subunit Cpha266_2166 31 None None None 119356947 Common - hypothetical protein Cpha266_1127 150 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 119356931 Common - oxidoreductase domain protein Cpha266_1110 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 119356507 Common - protein of unknown function UPF0047 Cpha266_0672 136 COG0432 COG0432, Uncharacterized conserved protein Function unknown 119358095 Common - transposase, IS4 Cpha266_2324 10 None None None 119356520 Common - metallophosphoesterase Cpha266_0685 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 119356535 Common - cytochrome bd ubiquinol oxidase, subunit I Cpha266_0700 167 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 119357506 Common - hypothetical protein Cpha266_1708 4 None None None 119357307 Common - protein of unknown function DUF955 Cpha266_1505 18 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 119356797 Common - proton-translocating NADH-quinone oxidoreductase, chain L Cpha266_0969 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 119357945 Common - Integral membrane protein TerC Cpha266_2160 103 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 119355917 Nonpathogen - hypothetical protein Cpha266_0067 1 None None None 119356185 Common - rfaE bifunctional protein Cpha266_0346 152 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 119356120 Common - hypothetical protein Cpha266_0276 7 None None None 119356294 Common - Secreted repeat of unknown function Cpha266_0456 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 119356860 Common - phospholipid/glycerol acyltransferase Cpha266_1033 57 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 119356495 Common - beta-lactamase Cpha266_0660 152 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 119357494 Common - hypothetical protein Cpha266_1695 6 None None None 119357122 Common - hypothetical protein Cpha266_1311 16 COG0433 COG0433, Predicted ATPase General function prediction only 119356912 Common - hypothetical protein Cpha266_1091 40 None None None 119356365 Common - phosphoribosylamine--glycine ligase Cpha266_0528 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 119358150 Common - hypothetical protein Cpha266_2382 13 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 119357333 Common - thiamine monophosphate synthase Cpha266_1531 180 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 119357203 Common - metallophosphoesterase Cpha266_1394 6 COG1409 Icc, Predicted phosphohydrolases General function prediction only 119357128 Common - protein of unknown function DUF214 Cpha266_1317 151 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119357934 Common - 6-phosphogluconolactonase Cpha266_2149 113 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 119356723 Common - N-6 DNA methylase Cpha266_0895 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 119356888 Nonpathogen - hypothetical protein Cpha266_1067 1 None None None 119356894 Common - NADH dehydrogenase Cpha266_1073 192 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 119357042 Nonpathogen - hypothetical protein Cpha266_1228 1 None None None 119356921 Common - ABC transporter related Cpha266_1100 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119356502 Common - pyridoxal phosphate biosynthetic protein PdxJ Cpha266_0667 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 119356919 Common - protein of unknown function DUF214 Cpha266_1098 118 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119356251 Common - putative NADPH-dependent glutamate synthase small subunit Cpha266_0413 214 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 119357633 Nonpathogen - TPR domain protein Cpha266_1837 3 None None None 119355913 Nonpathogen - hypothetical protein Cpha266_0063 1 None None None 119356058 Nonpathogen - hypothetical protein Cpha266_0211 4 None None None 119358147 Nonpathogen - bacteriochlorophyll 4-vinyl reductase Cpha266_2379 13 None None None 119358437 Common - RNP-1 like RNA-binding protein Cpha266_2673 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 119356707 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cpha266_0879 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119356940 Common - cob(I)alamin adenosyltransferase Cpha266_1120 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 119356654 Common - pentapeptide repeat protein Cpha266_0823 47 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 119356704 Common - ferredoxin Cpha266_0876 11 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 119355987 Common - DsrK protein Cpha266_0137 60 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 119358238 Common - glycerophosphoryl diester phosphodiesterase Cpha266_2470 73 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 119357723 Common - hypothetical protein Cpha266_1927 8 COG5513 COG5513, Predicted secreted protein Function unknown 119356023 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein Cpha266_0176 203 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 119357059 Common - Cl- channel, voltage-gated family protein Cpha266_1246 160 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 119357142 Common - CBS domain containing protein Cpha266_1331 10 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 119358292 Common - DNA methylase N-4/N-6 domain protein Cpha266_2524 106 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 119357161 Common - Cupin 2, conserved barrel domain protein Cpha266_1350 19 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 119356517 Common - vir region protein Cpha266_0682 5 None None None 119358485 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Cpha266_2721 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 119356551 Common - NUDIX hydrolase Cpha266_0717 83 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119358426 Common - zinc finger, CDGSH-type domain protein Cpha266_2662 23 COG3369 COG3369, Uncharacterized conserved protein Function unknown 119357978 Common - hypothetical protein Cpha266_2196 5 COG4634 COG4634, Uncharacterized protein conserved in bacteria Function unknown 119358158 Common - Adenylosuccinate synthase Cpha266_2390 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 119357153 Common - Cobyrinic acid a,c-diamide synthase Cpha266_1342 199 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119356984 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cpha266_1167 96 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 119357760 Common - indolepyruvate oxidoreductase subunit B Cpha266_1967 101 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 119356231 Nonpathogen - hypothetical protein Cpha266_0392 1 None None None 119358310 Common - aspartate kinase Cpha266_2542 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 119356769 Common - thioesterase superfamily protein Cpha266_0941 75 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 119356643 Common - DedA family protein Cpha266_0812 170 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 119356719 Nonpathogen - hypothetical protein Cpha266_0891 1 None None None 119356427 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Cpha266_0591 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 119357259 Common - IstB domain protein ATP-binding protein Cpha266_1451 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356834 Nonpathogen - hypothetical protein Cpha266_1007 3 None None None 119358303 Nonpathogen - phospholipase/Carboxylesterase Cpha266_2535 4 COG0400 COG0400, Predicted esterase General function prediction only 119355885 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Cpha266_0035 160 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 119357803 Common rpsI 30S ribosomal protein S9 Cpha266_2011 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 119357769 Nonpathogen - hypothetical protein Cpha266_1976 3 None None None 119358140 Common - ROK family protein Cpha266_2372 151 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 119357492 Common ubiA prenyltransferase Cpha266_1693 62 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 119356853 Nonpathogen - hypothetical protein Cpha266_1026 3 None None None 119358424 Common - transposase Cpha266_2660 25 COG5421 COG5421, Transposase DNA replication, recombination, and repair 119358474 Nonpathogen - hypothetical protein Cpha266_2710 3 None None None 119358266 Common - CMP/dCMP deaminase, zinc-binding Cpha266_2498 87 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 119357869 Nonpathogen - hypothetical protein Cpha266_2077 1 None None None 119357864 Common - ATP-dependent DNA helicase RecG Cpha266_2072 230 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 119356354 Common - excinuclease ABC, A subunit Cpha266_0517 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 119357092 Nonpathogen - hypothetical protein Cpha266_1279 1 None None None 119356356 Common - inner-membrane translocator Cpha266_0519 112 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 119357285 Common - transposase Cpha266_1478 18 None None None 119357370 Nonpathogen - hypothetical protein Cpha266_1568 1 None None None 119357089 Nonpathogen - hypothetical protein Cpha266_1276 4 None None None 119357168 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Cpha266_1357 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119356619 Nonpathogen - hypothetical protein Cpha266_0787 1 None None None 119356526 Common - phosphoesterase, PA-phosphatase related Cpha266_0691 14 None None None 119356336 Common - para-aminobenzoate synthase, subunit I Cpha266_0499 224 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 119357842 Common - CRISPR-associated protein, Csm1 family Cpha266_2050 25 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 119358446 Common prfA peptide chain release factor 1 Cpha266_2682 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 119357456 Common - phosphoribosylformylglycinamidine synthase I Cpha266_1655 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 119357345 Nonpathogen - DoxX family protein Cpha266_1543 4 None None None 119356127 Common - hypothetical protein Cpha266_0284 7 COG4861 COG4861, Uncharacterized protein conserved in bacteria Function unknown 119356031 Common - hypothetical protein Cpha266_0184 57 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 119358313 Common - homoserine kinase Cpha266_2545 105 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 119356275 Common - transcriptional regulator, LysR family Cpha266_0437 191 COG0583 LysR, Transcriptional regulator Transcription 119357460 Common - biotin/lipoate A/B protein ligase Cpha266_1659 53 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 119356404 Common - binding-protein-dependent transport systems inner membrane component Cpha266_0568 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119357607 Common - glycosyl transferase, family 2 Cpha266_1811 107 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119357211 Common - exodeoxyribonuclease V, gamma subunit Cpha266_1402 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 119358055 Nonpathogen - hypothetical protein Cpha266_2283 1 None None None 119358368 Common - hypothetical protein Cpha266_2600 3 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 119356092 Nonpathogen - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0245 12 COG1146 COG1146, Ferredoxin Energy production and conversion 119356785 Common - hypothetical protein Cpha266_0957 11 None None None 119357874 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Cpha266_2082 172 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 119356399 Nonpathogen - hypothetical protein Cpha266_0563 3 None None None 119357971 Nonpathogen - hypothetical protein Cpha266_2188 2 None None None 119356607 Common - RND efflux system, outer membrane lipoprotein, NodT family Cpha266_0775 129 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119357943 Common - aldehyde dehydrogenase Cpha266_2158 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119357644 Common - Radical SAM domain protein Cpha266_1848 45 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 119358205 Common - hypothetical protein Cpha266_2437 15 COG4485 COG4485, Predicted membrane protein Function unknown 119357615 Common - uncharacterized protein involved in exopolysaccharide biosynthesis-like Cpha266_1819 101 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119357318 Common - hypothetical protein Cpha266_1516 9 None None None 119357513 Common - Appr-1-p processing domain protein Cpha266_1715 26 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 119355941 Common - PilT protein domain protein Cpha266_0091 60 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119355876 Common - beta-lactamase domain protein Cpha266_0026 88 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 119356132 Common - hypothetical protein Cpha266_0289 11 None None None 119357379 Common - protein of unknown function DUF89 Cpha266_1577 40 COG1578 COG1578, Uncharacterized conserved protein Function unknown 119357545 Common - type I secretion system ATPase Cpha266_1748 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 119356005 Nonpathogen - protein of unknown function DUF169 Cpha266_0156 14 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 119356038 Nonpathogen - hypothetical protein Cpha266_0191 1 None None None 119358187 Common rpsS 30S ribosomal protein S19 Cpha266_2419 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 119357084 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Cpha266_1271 191 COG0281 SfcA, Malic enzyme Energy production and conversion 119358203 Common - hypothetical protein Cpha266_2435 6 None None None 119356373 Common - DNA polymerase I Cpha266_0536 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 119357235 Common - protein of unknown function DUF1568 Cpha266_1427 48 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357149 Common - Methyltransferase type 11 Cpha266_1338 71 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 119357658 Common - sodium/hydrogen exchanger Cpha266_1862 100 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 119356638 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cpha266_0807 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 119358462 Common - putative translaldolase Cpha266_2698 162 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 119356487 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_0652 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357559 Common - putative cold-shock DNA-binding domain protein Cpha266_1762 165 COG1278 CspC, Cold shock proteins Transcription 119358130 Common - nitrogen-fixing NifU domain protein Cpha266_2362 112 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 119356807 Common - 5 nucleotidase, deoxy, cytosolic type C Cpha266_0980 5 COG4502 COG4502, Uncharacterized protein conserved in bacteria Function unknown 119358094 Common - hypothetical protein Cpha266_2323 5 None None None 119356829 Common - C4-dicarboxylate transporter/malic acid transport protein Cpha266_1002 59 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 119357361 Nonpathogen - hypothetical protein Cpha266_1559 1 None None None 119358355 Common - hypothetical protein Cpha266_2587 28 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 119357548 Common - Integrase, catalytic region Cpha266_1751 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356209 Common - ribosome-binding factor A Cpha266_0370 107 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 119356238 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Cpha266_0399 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 119356193 Common - glycosyl transferase, family 2 Cpha266_0354 89 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119356873 Common - hypothetical protein Cpha266_1046 7 None None None 119356918 Common - hypothetical protein Cpha266_1097 16 None None None 119356480 Common - hypothetical protein Cpha266_0645 18 COG3899 COG3899, Predicted ATPase General function prediction only 119356280 Common - transcriptional regulator, Fis family Cpha266_0442 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 119358282 Common - glycosyl transferase, family 9 Cpha266_2514 95 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 119357479 Nonpathogen - hypothetical protein Cpha266_1678 4 None None None 119358450 Common - two component transcriptional regulator, LuxR family Cpha266_2686 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119356351 Common - major facilitator superfamily MFS_1 Cpha266_0514 12 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 119357196 Nonpathogen - hypothetical protein Cpha266_1387 5 None None None 119358335 Common - IstB domain protein ATP-binding protein Cpha266_2567 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356440 Common - hypothetical protein Cpha266_0604 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 119356734 Common - alanine dehydrogenase Cpha266_0906 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 119356694 Nonpathogen - photosystem P840 reaction center protein PscD Cpha266_0863 3 None None None 119357998 Nonpathogen - hypothetical protein Cpha266_2220 3 None None None 119356664 Common - protein of unknown function UPF0047 Cpha266_0833 120 COG0432 COG0432, Uncharacterized conserved protein Function unknown 119358001 Nonpathogen - hypothetical protein Cpha266_2223 6 None None None 119356593 Common - hypothetical protein Cpha266_0761 27 None None None 119357254 Common - hypothetical protein Cpha266_1446 19 None None None 119357311 Common - ABC transporter related Cpha266_1509 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119357717 Nonpathogen - hypothetical protein Cpha266_1921 1 None None None 119357927 Common - Peptidoglycan-binding domain 1 protein Cpha266_2142 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 119358308 Common - hypothetical protein Cpha266_2540 7 None None None 119357592 Common hemA glutamyl-tRNA reductase Cpha266_1795 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 119357575 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Cpha266_1778 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 119356003 Common trmE tRNA modification GTPase TrmE Cpha266_0153 220 COG0486 ThdF, Predicted GTPase General function prediction only 119358225 Common - putative metalloendopeptidase, glycoprotease family Cpha266_2457 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 119357302 Nonpathogen - hypothetical protein Cpha266_1500 1 None None None 119356568 Common - molybdenum cofactor biosynthesis protein A Cpha266_0734 206 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 119358383 Common - NAD-dependent epimerase/dehydratase Cpha266_2616 169 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356473 Nonpathogen - hypothetical protein Cpha266_0638 1 None None None 119356485 Common - helix-turn-helix domain protein Cpha266_0650 46 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 119356198 Common - glycosyl transferase, group 1 Cpha266_0359 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119358367 Nonpathogen - hypothetical protein Cpha266_2599 1 None None None 119356941 Common - transport system permease protein Cpha266_1121 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119356000 Nonpathogen - hypothetical protein Cpha266_0150 1 None None None 119357661 Common - gamma-glutamyl phosphate reductase Cpha266_1865 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 119356081 Common - DNA-directed RNA polymerase subunit beta' Cpha266_0234 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 119357227 Common - Stress responsive alpha-beta barrel domain protein Cpha266_1419 21 None None None 119358278 Common rpsR 30S ribosomal protein S18 Cpha266_2510 211 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 119357244 Common - CRISPR-associated helicase Cas3 Cpha266_1436 75 COG1203 COG1203, Predicted helicases General function prediction only 119356960 Common - hypothetical protein Cpha266_1143 4 None None None 119356627 Common - NADPH-dependent FMN reductase Cpha266_0796 98 COG0431 COG0431, Predicted flavoprotein General function prediction only 119356105 Nonpathogen - hypothetical protein Cpha266_0260 1 None None None 119356415 Common - tRNA(Ile)-lysidine synthetase Cpha266_0579 195 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 119356223 Common - Polyprenyl synthetase Cpha266_0384 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 119356620 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0788 80 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 119356973 Common - short-chain dehydrogenase/reductase SDR Cpha266_1156 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 119357409 Nonpathogen - hypothetical protein Cpha266_1608 1 None None None 119357569 Common - beta-lactamase domain protein Cpha266_1772 127 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 119358189 Common rplW 50S ribosomal protein L23 Cpha266_2421 205 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 119357526 Common - aminotransferase, class I and II Cpha266_1729 235 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119357426 Common - phage transcriptional regulator, AlpA Cpha266_1625 6 COG3311 AlpA, Predicted transcriptional regulator Transcription 119355978 Common - sulfite reductase, dissimilatory-type alpha subunit Cpha266_0128 46 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 119357796 Common - short chain dehydrogenase Cpha266_2003 236 COG3347 COG3347, Uncharacterized conserved protein Function unknown 119356320 Common - protein of unknown function DUF1499 Cpha266_0483 21 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 119358111 Common - Chromosome segregation ATPases-like Cpha266_2343 101 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119357291 Common - putative reverse transcriptase/maturase family protein Cpha266_1485 87 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 119358404 Common - PilT protein domain protein Cpha266_2640 54 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119355893 Common - hypothetical protein Cpha266_0043 11 None None None 119357556 Common - queuine tRNA-ribosyltransferase Cpha266_1759 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 119357984 Common - TPR repeat-containing protein Cpha266_2203 141 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 119356744 Common - Rubrerythrin Cpha266_0916 82 COG1592 COG1592, Rubrerythrin Energy production and conversion 119358044 Common - ABC transporter related Cpha266_2272 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 119358472 Common - ATP synthase F0, C subunit Cpha266_2708 14 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 119356228 Common rpsT 30S ribosomal protein S20 Cpha266_0389 130 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 119358118 Common - PAS/PAC sensor hybrid histidine kinase Cpha266_2350 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119357072 Nonpathogen - methyl-viologen-reducing hydrogenase, delta subunit Cpha266_1259 32 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 119356126 Common - hypothetical protein Cpha266_0283 7 COG4849 COG4849, Uncharacterized protein conserved in bacteria Function unknown 119356074 Nonpathogen secE preprotein translocase subunit SecE Cpha266_0227 10 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 119356204 Common - glutaredoxin 2 Cpha266_0365 15 None None None 119356687 Common - MotA/TolQ/ExbB proton channel Cpha266_0856 125 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 119357582 Common - putative PAS/PAC sensor protein Cpha266_1785 8 None None None 119356305 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cpha266_0468 76 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 119356787 Common - TPR repeat-containing protein Cpha266_0959 123 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 119357624 Nonpathogen - nucleoside-diphosphate-sugar pyrophosphorylase Cpha266_1828 5 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 119357651 Common - protease Do Cpha266_1855 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 119357939 Common - protein of unknown function DUF541 Cpha266_2154 27 COG2859 COG2859, Uncharacterized protein conserved in bacteria Function unknown 119356349 Common - hydroxylamine reductase Cpha266_0512 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 119357532 Nonpathogen - hypothetical protein Cpha266_1735 2 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119357277 Common - uncharacterized domain 1 Cpha266_1470 69 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 119356459 Common - CMP/dCMP deaminase, zinc-binding Cpha266_0624 207 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 119357135 Common - arginine repressor, ArgR Cpha266_1324 80 COG1438 ArgR, Arginine repressor Transcription 119355961 Common - biotin--acetyl-CoA-carboxylase ligase Cpha266_0111 209 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 119358126 Common - metallophosphoesterase Cpha266_2358 87 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 119356083 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Cpha266_0236 184 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 119356543 Common - shikimate 5-dehydrogenase Cpha266_0708 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 119358173 Common rpmD 50S ribosomal protein L30 Cpha266_2405 117 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 119357736 Common - transcriptional regulator, BadM/Rrf2 family Cpha266_1940 169 COG1959 COG1959, Predicted transcriptional regulator Transcription 119358487 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Cpha266_2723 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 119356311 Common - hypothetical protein Cpha266_0474 14 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 119357693 Nonpathogen - hypothetical protein Cpha266_1897 2 None None None 119355906 Common - peptidase M12A, astacin Cpha266_0056 8 None None None 119356318 Nonpathogen - ferrochelatase Cpha266_0481 7 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 119357335 Common - phosphomethylpyrimidine kinase Cpha266_1533 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 119357772 Common - Radical SAM domain protein Cpha266_1979 143 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 119358396 Common - glycosyl transferase, group 1 Cpha266_2630 39 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119356993 Nonpathogen - hypothetical protein Cpha266_1176 1 None None None 119358439 Common - domain of unknown function DUF1731 Cpha266_2675 107 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 119357366 Common - efflux transporter, RND family, MFP subunit Cpha266_1564 136 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119356869 Common - phosphate uptake regulator, PhoU Cpha266_1042 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 119356530 Nonpathogen - hypothetical protein Cpha266_0695 1 None None None 119357447 Nonpathogen - transposase IS3/IS911 family protein Cpha266_1646 7 None None None 119356062 Common - rare lipoprotein A Cpha266_0215 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 119358327 Common - CrcB protein Cpha266_2559 191 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 119355994 Common - twin-arginine translocation pathway signal Cpha266_0144 108 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 119357731 Common - exsB protein Cpha266_1935 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 119356021 Common - uroporphyrinogen decarboxylase Cpha266_0174 183 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 119357641 Common - type I secretion outer membrane protein, TolC family Cpha266_1845 95 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119358250 Common - Excinuclease ABC, C subunit domain protein Cpha266_2482 4 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 119355989 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0139 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 119357839 Common - CRISPR-associated RAMP protein, Csm4 family Cpha266_2047 12 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 119358033 Common - DnaK like protein Cpha266_2261 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 119356249 Common - lipid-A-disaccharide synthase Cpha266_0411 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 119355863 Common - hypothetical protein Cpha266_0007 27 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357539 Common - protein of unknown function DUF404 Cpha266_1742 90 COG2308 COG2308, Uncharacterized conserved protein Function unknown 119357855 Nonpathogen - hypothetical protein Cpha266_2063 1 None None None 119357021 Nonpathogen - hypothetical protein Cpha266_1206 1 None None None 119357402 Common - protein of unknown function DUF264 Cpha266_1601 10 COG1783 XtmB, Phage terminase large subunit General function prediction only 119357324 Common trmD tRNA (guanine-N(1)-)-methyltransferase Cpha266_1522 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 119358459 Nonpathogen - hypothetical protein Cpha266_2695 3 None None None 119356777 Nonpathogen - hypothetical protein Cpha266_0949 2 None None None 119357740 Common - Legionella vir region protein Cpha266_1944 3 None None None 119356673 Common - ABC transporter related Cpha266_0842 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119356135 Common - DNA polymerase, beta domain protein region Cpha266_0292 19 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 119356908 Common - Lytic transglycosylase, catalytic Cpha266_1087 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119357080 Common - HhH-GPD family protein Cpha266_1267 20 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 119356044 Nonpathogen - hypothetical protein Cpha266_0197 2 None None None 119358416 Common - IstB domain protein ATP-binding protein Cpha266_2652 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357184 Common - helix-turn-helix domain protein Cpha266_1375 16 COG2944 COG2944, Predicted transcriptional regulator Transcription 119356452 Common - small multidrug resistance protein Cpha266_0616 144 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 119357034 Nonpathogen - hypothetical protein Cpha266_1220 1 None None None 119356953 Nonpathogen - hypothetical protein Cpha266_1133 2 None None None 119357561 Common - GatB/Yqey domain protein Cpha266_1764 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 119356616 Nonpathogen - hypothetical protein Cpha266_0784 1 None None None 119357387 Common - Patatin Cpha266_1585 36 COG3621 COG3621, Patatin General function prediction only 119358395 Common - hypothetical protein Cpha266_2628 11 None None None 119356675 Common - protein of unknown function DUF218 Cpha266_0844 26 COG1434 COG1434, Uncharacterized conserved protein Function unknown 119356585 Nonpathogen - hypothetical protein Cpha266_0752 1 None None None 119358271 Common rpmI 50S ribosomal protein L35 Cpha266_2503 128 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 119357782 Common - amidophosphoribosyltransferase Cpha266_1989 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 119358087 Common - heat shock protein Hsp20 Cpha266_2316 83 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 119357305 Nonpathogen - hypothetical protein Cpha266_1503 6 None None None 119355976 Common - cobyrinic acid a,c-diamide synthase Cpha266_0126 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 119356458 Common - succinyl-CoA synthetase, beta subunit Cpha266_0623 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 119358452 Common - hypothetical protein Cpha266_2688 20 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119355915 Common - hypothetical protein Cpha266_0065 7 None None None 119358109 Common - glycosyl transferase, family 2 Cpha266_2341 192 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119355871 Common - Rhodopirellula transposase family protein Cpha266_0018 13 None None None 119356447 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cpha266_0611 197 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 119356363 Common - tetraacyldisaccharide 4'-kinase Cpha266_0526 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 119356049 Nonpathogen - chlorosome envelope protein B Cpha266_0202 3 None None None 119356847 Nonpathogen - hypothetical protein Cpha266_1020 3 None None None 119357077 Common - carbohydrate kinase, YjeF related protein Cpha266_1264 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 119357066 Common - multi-sensor signal transduction histidine kinase Cpha266_1253 183 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119357372 Common - Glutamate synthase (NADPH) Cpha266_1570 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 119358501 Common - RNA methyltransferase, TrmA family Cpha266_2737 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 119357094 Common - Integrase, catalytic region Cpha266_1281 77 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357264 Common - zinc transporter ZupT Cpha266_1456 109 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 119356804 Common folE GTP cyclohydrolase I Cpha266_0976 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 119356759 Nonpathogen secG preprotein translocase subunit SecG Cpha266_0931 3 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 119358040 Common - MscS Mechanosensitive ion channel Cpha266_2268 133 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 119357312 Common - amino acid permease-associated region Cpha266_1510 175 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 119356923 Common - short-chain dehydrogenase/reductase SDR Cpha266_1102 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119356446 Nonpathogen - hypothetical protein Cpha266_0610 1 None None None 119356968 Common - putative transcriptional regulator Cpha266_1151 8 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119357096 Nonpathogen - hypothetical protein Cpha266_1283 1 None None None 119356782 Common - outer membrane efflux protein Cpha266_0954 145 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119357802 Common rpsB 30S ribosomal protein S2 Cpha266_2010 227 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 119357085 Common - hypothetical protein Cpha266_1272 4 None None None 119357553 Common - hypothetical protein Cpha266_1756 11 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 119357048 Common - SNF2-related protein Cpha266_1235 135 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119357827 Common - hypothetical protein Cpha266_2035 20 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 119357500 Common - hypothetical protein Cpha266_1702 7 None None None 119356580 Common - hypothetical protein Cpha266_0747 11 None None None 119356203 Common hisS histidyl-tRNA synthetase Cpha266_0364 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119358093 Common - hypothetical protein Cpha266_2322 9 None None None 119357151 Common - basic membrane lipoprotein Cpha266_1340 103 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 119356412 Common - DNA repair protein RecN Cpha266_0576 200 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 119356419 Common - bacteriochlorophyll/chlorophyll a synthase Cpha266_0583 70 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 119356750 Common - S-adenosylmethionine synthetase Cpha266_0922 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 119357457 Common - phosphoribosylformylglycinamidine synthase, purS Cpha266_1656 95 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 119356497 Common - ABC transporter related Cpha266_0662 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 119358107 Common - transposase, IS4 family protein Cpha266_2339 30 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 119357511 Nonpathogen - conserved hypothetical cytosolic protein Cpha266_1713 5 None None None 119356823 Common - DNA repair protein RadA Cpha266_0996 214 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 119358366 Common - hypothetical protein Cpha266_2598 7 None None None 119358047 Nonpathogen - hypothetical protein Cpha266_2275 4 COG4980 GvpP, Gas vesicle protein General function prediction only 119357876 Common - OmpA/MotB domain protein Cpha266_2084 162 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119357499 Common - helix-turn-helix domain protein Cpha266_1701 10 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 119357605 Common - cytochrome c assembly protein Cpha266_1808 88 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 119358319 Common - UspA domain protein Cpha266_2551 116 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119357375 Common - peptidase M50 Cpha266_1573 201 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 119356809 Nonpathogen - hypothetical protein Cpha266_0982 3 None None None 119358242 Common - ABC-3 protein Cpha266_2474 133 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 119356145 Common - DedA protein Cpha266_0303 110 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 119357685 Common - putative transcriptional regulator, MerR family Cpha266_1889 86 COG0789 SoxR, Predicted transcriptional regulators Transcription 119356879 Common - Patatin Cpha266_1052 14 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119358207 Common - glycosyl transferase, group 1 Cpha266_2439 46 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119358020 Common - hypothetical protein Cpha266_2245 4 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119356276 Common - ABC transporter related Cpha266_0438 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119356387 Common leuS leucyl-tRNA synthetase Cpha266_0551 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119357167 Common - glycosyl transferase, group 1 Cpha266_1356 129 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119355883 Common secD preprotein translocase subunit SecD Cpha266_0033 219 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 119357214 Common - hypothetical protein Cpha266_1405 13 None None None 119358070 Nonpathogen - hypothetical protein Cpha266_2298 4 None None None 119357856 Nonpathogen - hypothetical protein Cpha266_2064 1 None None None 119356425 Common - phosphofructokinase Cpha266_0589 157 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 119357474 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Cpha266_1673 165 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 119358071 Nonpathogen - bacteriochlorophyll C binding protein Cpha266_2299 3 None None None 119356157 Common - hypothetical protein Cpha266_0315 6 None None None 119357642 Common - putative outer membrane adhesin like proteiin Cpha266_1846 138 None None None 119357574 Common - K+ potassium transporter Cpha266_1777 89 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 119356380 Common - Inositol-phosphate phosphatase Cpha266_0543 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 119358200 Nonpathogen - hypothetical protein Cpha266_2432 1 None None None 119356443 Nonpathogen - hypothetical protein Cpha266_0607 5 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 119357025 Common - DNA topoisomerase, type IA, zn finger domain protein Cpha266_1210 22 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 119356898 Common - hypothetical protein Cpha266_1077 16 None None None 119356764 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_0936 72 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356328 Common hisH imidazole glycerol phosphate synthase subunit HisH Cpha266_0491 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 119358259 Common - malonyl CoA-acyl carrier protein transacylase Cpha266_2491 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 119357882 Common - alpha/beta hydrolase fold Cpha266_2090 149 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119357823 Common thyX FAD-dependent thymidylate synthase Cpha266_2031 59 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 119357436 Common - nuclear protein SET Cpha266_1635 10 COG2940 COG2940, Proteins containing SET domain General function prediction only 119357593 Common - porphobilinogen deaminase Cpha266_1796 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 119356646 Common smpB SsrA-binding protein Cpha266_0815 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 119357968 Common - protein of unknown function DUF433 Cpha266_2185 11 COG2442 COG2442, Uncharacterized conserved protein Function unknown 119357774 Common - endonuclease IV Cpha266_1981 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 119357054 Common - efflux transporter, RND family, MFP subunit Cpha266_1241 119 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119358457 Common - Alkaline phosphatase Cpha266_2693 82 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 119357941 Common - YbaK/prolyl-tRNA synthetase associated region Cpha266_2156 41 COG2606 EbsC, Uncharacterized conserved protein Function unknown 119356649 Nonpathogen - hypothetical protein Cpha266_0818 3 None None None 119356334 Common - phosphatidate cytidylyltransferase Cpha266_0497 13 COG0170 SEC59, Dolichol kinase Lipid metabolism 119357242 Common - CRISPR-associated protein, Csd1 family Cpha266_1434 28 None None None 119356852 Nonpathogen - hypothetical protein Cpha266_1025 1 None None None 119356084 Common - translation elongation factor P Cpha266_0237 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 119357601 Common - delta-aminolevulinic acid dehydratase Cpha266_1804 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 119357647 Common - thiamine biosynthesis protein ThiC Cpha266_1851 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 119356051 Common - Nucleotidyl transferase Cpha266_0204 191 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 119356524 Common - glycosyl transferase, family 2 Cpha266_0689 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119356832 Common - hypothetical protein Cpha266_1005 6 COG2267 PldB, Lysophospholipase Lipid metabolism 119357490 Common - hypothetical protein Cpha266_1691 8 COG5649 COG5649, Uncharacterized conserved protein Function unknown 119358104 Common - lipase, class 3 Cpha266_2334 104 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119357767 Nonpathogen - hypothetical protein Cpha266_1974 1 None None None 119357283 Nonpathogen - hypothetical protein Cpha266_1476 1 None None None 119357148 Nonpathogen - hypothetical protein Cpha266_1337 3 None None None 119358493 Common - S-adenosyl-methyltransferase MraW Cpha266_2729 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 119357567 Common - TPR repeat-containing protein Cpha266_1770 87 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 119357124 Common - Lipocalin family protein Cpha266_1313 74 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 119357751 Common - multi-sensor hybrid histidine kinase Cpha266_1957 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119356728 Common - protein of unknown function DUF323 Cpha266_0900 113 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119356022 Common - CoB--CoM heterodisulfide reductase Cpha266_0175 50 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 119358121 Common - protein of unknown function DUF937 Cpha266_2353 31 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 119357849 Common - hypothetical protein Cpha266_2057 13 None None None 119358284 Common - thioesterase superfamily protein Cpha266_2516 32 COG0824 FcbC, Predicted thioesterase General function prediction only 119358467 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Cpha266_2703 182 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 119356509 Common - UvrD/REP helicase Cpha266_0674 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 119356896 Common - cyclopropane fatty acyl phospholipid synthase Cpha266_1075 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 119356230 Common - FolC bifunctional protein Cpha266_0391 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 119357115 Common - carboxyl-terminal protease Cpha266_1304 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 119358233 Common - MtN3 and saliva related transmembrane protein Cpha266_2465 32 COG4095 COG4095, Uncharacterized conserved protein Function unknown 119356986 Common ksgA dimethyladenosine transferase Cpha266_1169 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 119356680 Common - 2-isopropylmalate synthase Cpha266_0849 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 119357721 Common - Integrase, catalytic region Cpha266_1925 62 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357110 Common - Ankyrin Cpha266_1298 28 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 119355934 Common - hypothetical protein Cpha266_0084 63 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119357342 Nonpathogen - hypothetical protein Cpha266_1540 3 None None None 119358165 Common rpsD 30S ribosomal protein S4 Cpha266_2397 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 119357160 Nonpathogen - hypothetical protein Cpha266_1349 1 None None None 119357937 Common - multi-sensor hybrid histidine kinase Cpha266_2152 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119358166 Common - 30S ribosomal protein S11 Cpha266_2398 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 119357518 Common - OsmC family protein Cpha266_1720 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119357039 Common - hypothetical protein Cpha266_1225 8 COG5340 COG5340, Predicted transcriptional regulator Transcription 119357132 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Cpha266_1321 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 119357466 Common - outer membrane efflux protein Cpha266_1665 142 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119356104 Nonpathogen - hypothetical protein Cpha266_0259 1 None None None 119357271 Common - oxidoreductase FAD/NAD(P)-binding domain protein Cpha266_1463 140 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 119357931 Common - hypothetical protein Cpha266_2146 6 COG5473 COG5473, Predicted integral membrane protein Function unknown 119356937 Common - cobyric acid synthase CobQ Cpha266_1117 153 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 119357952 Common - oxidoreductase FAD/NAD(P)-binding domain protein Cpha266_2167 119 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 119356420 Common - anthranilate phosphoribosyltransferase Cpha266_0584 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 119356430 Common - alpha-glucan phosphorylases Cpha266_0594 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 119357109 Common - hypothetical protein Cpha266_1297 12 None None None 119357252 Common - hypothetical protein Cpha266_1444 40 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 119356066 Common - photosystem P840 reaction center, large subunit Cpha266_0219 11 None None None 119355914 Common - hypothetical protein Cpha266_0064 8 None None None 119356437 Common - Glycine hydroxymethyltransferase Cpha266_0601 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 119356709 Common - multi-sensor signal transduction histidine kinase Cpha266_0881 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 119357420 Common - DNA repair protein RadC Cpha266_1619 175 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 119358137 Common - protein of unknown function UPF0118 Cpha266_2369 75 COG0628 PerM, Predicted permease General function prediction only 119358411 Nonpathogen - PilT protein domain protein Cpha266_2647 1 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119356567 Common - MOSC domain containing protein Cpha266_0733 29 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 119357019 Common - outer membrane autotransporter barrel domain Cpha266_1203 97 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 119356733 Nonpathogen - hypothetical protein Cpha266_0905 1 None None None 119358294 Nonpathogen - mucin-associated surface protein (MASP) Cpha266_2526 1 None None None 119357891 Common - magnesium transporter Cpha266_2099 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 119355929 Common - histidine kinase Cpha266_0079 72 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119355920 Common - helix-turn-helix protein, CopG family Cpha266_0070 9 None None None 119356794 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0966 166 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 119355946 Common - outer membrane efflux protein Cpha266_0096 137 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119358227 Common - carbamoyl phosphate synthase small subunit Cpha266_2459 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 119357158 Common - IstB domain protein ATP-binding protein Cpha266_1347 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356562 Common - UBA/THIF-type NAD/FAD binding protein Cpha266_0728 205 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 119357903 Common - IstB domain protein ATP-binding protein Cpha266_2111 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356605 Common - hypothetical protein Cpha266_0773 11 None None None 119357813 Common - protein of unknown function DUF477 Cpha266_2021 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 119358246 Common - 2-isopropylmalate synthase Cpha266_2478 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 119357898 Nonpathogen - hypothetical protein Cpha266_2106 1 None None None 119357486 Common - ABC transporter related Cpha266_1685 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119357613 Common - transferase hexapeptide repeat containing protein Cpha266_1817 202 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 119356113 Common - transposase, IS4 family protein Cpha266_0269 18 None None None 119357729 Common trpA tryptophan synthase subunit alpha Cpha266_1933 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 119356180 Common - phosphoenolpyruvate-protein phosphotransferase Cpha266_0341 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 119357331 Common - carboxyl-terminal protease Cpha266_1529 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 119357484 Common - inner-membrane translocator Cpha266_1683 147 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 119357925 Common - hypothetical protein Cpha266_2140 31 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 119356256 Common rpsA 30S ribosomal protein S1 Cpha266_0418 222 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 119356533 Common - ABC transporter, transmembrane region, type 1 Cpha266_0698 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 119355900 Common - Redoxin domain protein Cpha266_0050 147 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119356375 Common - hypothetical protein Cpha266_0538 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 119357544 Common - secretion protein HlyD family protein Cpha266_1747 111 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119357130 Common - phosphate-binding protein, putative Cpha266_1319 9 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 119356677 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Cpha266_0846 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 119356042 Common - short chain dehydrogenase Cpha266_0195 237 COG3347 COG3347, Uncharacterized conserved protein Function unknown 119357780 Common - hypothetical protein Cpha266_1987 8 None None None 119357710 Nonpathogen - hypothetical protein Cpha266_1914 2 None None None 119357588 Common - chlorophyll synthesis pathway, BchC Cpha266_1791 103 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 119357322 Common - HhH-GPD family protein Cpha266_1520 215 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 119357627 Common - glycosyl transferase, WecB/TagA/CpsF family Cpha266_1831 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 119357554 Nonpathogen - hypothetical protein Cpha266_1757 9 None None None 119358213 Common obgE GTPase ObgE Cpha266_2445 249 COG0536 Obg, Predicted GTPase General function prediction only 119358031 Common - protein of unknown function DUF323 Cpha266_2259 103 COG1262 COG1262, Uncharacterized conserved protein Function unknown 119357756 Common - ferric uptake regulator, Fur family Cpha266_1963 133 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 119357973 Nonpathogen - hypothetical protein Cpha266_2190 1 None None None 119356779 Common - alpha amylase, catalytic region Cpha266_0951 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 119356623 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0791 72 COG0457 NrfG, FOG: TPR repeat General function prediction only 119357032 Common - transposase, mutator type Cpha266_1218 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356956 Common - IstB domain protein ATP-binding protein Cpha266_1137 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119358400 Nonpathogen - hypothetical protein Cpha266_2636 1 COG4907 COG4907, Predicted membrane protein Function unknown 119356600 Common - protein of unknown function DUF86 Cpha266_0768 22 COG2445 COG2445, Uncharacterized conserved protein Function unknown 119356461 Common - 2-nitropropane dioxygenase, NPD Cpha266_0626 97 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 119356906 Common - alpha-amylase family protein Cpha266_1085 42 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 119356406 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0570 120 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 119357068 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Cpha266_1255 148 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 119355970 Common - Formate dehydrogenase Cpha266_0120 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 119357404 Common - Eco57I restriction endonuclease Cpha266_1603 61 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 119358479 Common - acetyl-CoA hydrolase/transferase Cpha266_2715 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 119357653 Nonpathogen - hypothetical protein Cpha266_1857 3 None None None 119356467 Nonpathogen - hypothetical protein Cpha266_0632 1 None None None 119357001 Common - fumarate hydratase, class II Cpha266_1185 212 COG0114 FumC, Fumarase Energy production and conversion 119355879 Common - hypothetical protein Cpha266_0029 14 COG5501 COG5501, Predicted secreted protein Function unknown 119356128 Nonpathogen - hypothetical protein Cpha266_0285 2 None None None 119357033 Common - hypothetical protein Cpha266_1219 2 None None None 119357472 Common - OmpA/MotB domain protein Cpha266_1671 173 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119356360 Common - hypothetical protein Cpha266_0523 5 None None None 119358025 Nonpathogen - hypothetical protein Cpha266_2253 6 None None None 119357664 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cpha266_1868 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 119357388 Common - hypothetical protein Cpha266_1586 5 None None None 119356086 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Cpha266_0239 186 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 119356214 Common gmk guanylate kinase Cpha266_0375 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 119358273 Common - phenylalanyl-tRNA synthetase, alpha subunit Cpha266_2505 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 119358449 Common - Legionella vir region protein Cpha266_2685 5 None None None 119357678 Common - Xanthine/uracil/vitamin C permease Cpha266_1882 135 COG2252 COG2252, Permeases General function prediction only 119357394 Common - carboxyl transferase Cpha266_1593 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 119356211 Common - riboflavin biosynthesis protein RibF Cpha266_0372 211 COG0196 RibF, FAD synthase Coenzyme metabolism 119357537 Common - putative transcriptional regulator Cpha266_1740 27 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119357639 Common - cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters Cpha266_1843 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 119357788 Common - dTDP-glucose 4,6-dehydratase Cpha266_1995 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 119356460 Nonpathogen - hypothetical protein Cpha266_0625 4 None None None 119356289 Nonpathogen - cytochrome c, putative Cpha266_0451 6 COG2863 COG2863, Cytochrome c553 Energy production and conversion 119357879 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_2087 98 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 119356849 Common - hypothetical protein Cpha266_1022 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 119356868 Common - phosphate ABC transporter, ATPase subunit Cpha266_1041 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 119355954 Nonpathogen - hypothetical protein Cpha266_0104 1 None None None 119356456 Common - efflux transporter, RND family, MFP subunit Cpha266_0621 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119358384 Common - polysaccharide deacetylase Cpha266_2617 63 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 119357306 Common - PIN domain protein Cpha266_1504 8 None None None 119358003 Common - conserved hypothetical transposase Cpha266_2225 26 None None None 119356247 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cpha266_0408 152 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119357837 Nonpathogen - hypothetical protein Cpha266_2045 3 None None None 119357888 Common - parB-like partition proteins Cpha266_2096 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 119356991 Nonpathogen - hypothetical protein Cpha266_1174 1 None None None 119357920 Nonpathogen - Tetratricopeptide TPR_3 Cpha266_2135 1 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 119358378 Common - NAD-dependent epimerase/dehydratase Cpha266_2610 198 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356614 Nonpathogen - hypothetical protein Cpha266_0782 1 None None None 119357364 Common - RND efflux system, outer membrane lipoprotein, NodT family Cpha266_1562 132 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119356154 Common - cobyrinic acid a,c-diamide synthase Cpha266_0312 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 119355967 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Cpha266_0117 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 119356344 Common - cytochrome c, putative Cpha266_0507 14 None None None 119358325 Common - glutamate-1-semialdehyde-2,1-aminomutase Cpha266_2557 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 119358484 Common - UDP-N-acetylmuramate--alanine ligase Cpha266_2720 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 119358174 Common rpsE 30S ribosomal protein S5 Cpha266_2406 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 119356313 Common - conserved hypothetical protein 730 Cpha266_0476 102 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 119356165 Nonpathogen - hypothetical protein Cpha266_0323 2 None None None 119357468 Common - ABC transporter related Cpha266_1667 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119357719 Common - hypothetical protein Cpha266_1923 6 None None None 119357581 Nonpathogen - hypothetical protein Cpha266_1784 1 None None None 119356549 Nonpathogen - hypothetical protein Cpha266_0714 3 None None None 119357737 Common - alpha/beta hydrolase fold Cpha266_1941 145 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119357619 Common - polysaccharide export protein Cpha266_1823 110 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 119358156 Common - light-independent protochlorophyllide reductase subunit N Cpha266_2388 27 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119358012 Common - Uracil-DNA glycosylase superfamily Cpha266_2236 8 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 119358425 Common - CTP synthetase Cpha266_2661 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 119358344 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Cpha266_2576 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 119357799 Common recX recombination regulator RecX Cpha266_2007 14 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 119356554 Common - hydrogenase expression/synthesis, HypA Cpha266_0720 99 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 119356840 Nonpathogen - phospholipid/glycerol acyltransferase Cpha266_1013 10 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 119357027 Common - GCN5-related N-acetyltransferase Cpha266_1212 47 COG0456 RimI, Acetyltransferases General function prediction only 119356039 Common - hypothetical protein Cpha266_0192 14 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 119357186 Common - CopG domain protein DNA-binding domain protein Cpha266_1377 13 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 119357709 Nonpathogen - hypothetical protein Cpha266_1913 5 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 119356118 Common - IstB domain protein ATP-binding protein Cpha266_0274 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119358418 Nonpathogen - hypothetical protein Cpha266_2654 1 None None None 119356171 Common - Rhodopirellula transposase family protein Cpha266_0332 9 None None None 119356414 Common - phosphatidylserine decarboxylase Cpha266_0578 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 119358019 Nonpathogen - hypothetical protein Cpha266_2244 2 None None None 119358211 Common - Phosphotransferase system, phosphocarrier protein HPr Cpha266_2443 153 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 119356072 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Cpha266_0225 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 119357200 Common - hypothetical protein Cpha266_1391 15 None None None 119356107 Nonpathogen - hypothetical protein Cpha266_0263 2 None None None 119356625 Nonpathogen - hypothetical protein Cpha266_0794 1 None None None 119358364 Common - protein of unknown function DUF218 Cpha266_2596 73 COG1434 COG1434, Uncharacterized conserved protein Function unknown 119356199 Common - glycosyl transferase, family 9 Cpha266_0360 34 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 119356398 Common - Methyltransferase type 12 Cpha266_0562 47 COG3897 COG3897, Predicted methyltransferase General function prediction only 119358085 Common - Mg-protoporphyrin IX methyl transferase Cpha266_2314 92 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 119356990 Common - Carotene 7,8-desaturase Cpha266_1173 26 COG3349 COG3349, Uncharacterized conserved protein Function unknown 119356047 Common - Radical SAM domain protein Cpha266_0200 93 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119355895 Common - glycyl-tRNA synthetase Cpha266_0045 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 119358042 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_2270 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357205 Nonpathogen - hypothetical protein Cpha266_1396 1 None None None 119357848 Nonpathogen - hypothetical protein Cpha266_2056 5 None None None 119357385 Nonpathogen - hypothetical protein Cpha266_1583 2 None None None 119358402 Nonpathogen - hypothetical protein Cpha266_2638 1 None None None 119356911 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Cpha266_1090 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 119358503 Common - phosphoesterase, PA-phosphatase related Cpha266_2739 31 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 119358182 Common rpsQ 30S ribosomal protein S17 Cpha266_2414 234 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 119356784 Common - histidine triad (HIT) protein Cpha266_0956 98 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 119357743 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Cpha266_1949 72 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357622 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Cpha266_1826 27 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 119357062 Nonpathogen - hypothetical protein Cpha266_1249 1 None None None 119357262 Common - conserved hypothetical protein 730 Cpha266_1454 129 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 119357906 Common - putative thiol-disulphide oxidoreductase DCC Cpha266_2114 32 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 119357174 Common - hypothetical protein Cpha266_1364 15 None None None 119356575 Common - nitrogen regulatory protein P-II Cpha266_0742 182 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 119358470 Common - F0F1 ATP synthase subunit delta Cpha266_2706 173 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 119356176 Common - signal recognition particle-docking protein FtsY Cpha266_0337 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 119356828 Common - OsmC family protein Cpha266_1001 29 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119357247 Common - hypothetical protein Cpha266_1439 20 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 119357083 Nonpathogen - hypothetical protein Cpha266_1270 8 None None None 119357020 Common - two component transcriptional regulator, winged helix family Cpha266_1205 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119356222 Common - DNA protecting protein DprA Cpha266_0383 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 119356205 Nonpathogen - hypothetical protein Cpha266_0366 1 None None None 119356027 Nonpathogen - hypothetical protein Cpha266_0180 3 None None None 119358116 Common - outer membrane autotransporter barrel domain Cpha266_2348 123 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 119356242 Common - polysaccharide biosynthesis protein Cpha266_0403 41 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 119357352 Common - hypothetical protein Cpha266_1550 27 COG4704 COG4704, Uncharacterized protein conserved in bacteria Function unknown 119356012 Common - multi-sensor hybrid histidine kinase Cpha266_0165 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119356972 Common - hypothetical protein Cpha266_1155 11 None None None 119356097 Common - phosphoserine phosphatase SerB Cpha266_0250 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 119356282 Common - TonB-dependent receptor Cpha266_0444 110 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 119356959 Common - hypothetical protein Cpha266_1142 4 None None None 119357996 Common - protein of unknown function DUF1568 Cpha266_2218 48 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119356599 Common - protein of unknown function DUF86 Cpha266_0767 22 COG2445 COG2445, Uncharacterized conserved protein Function unknown 119356121 Nonpathogen - hypothetical protein Cpha266_0277 1 None None None 119357440 Nonpathogen - hypothetical protein Cpha266_1639 3 None None None 119357748 Common - Integrase, catalytic region Cpha266_1954 152 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357981 Nonpathogen - hypothetical protein Cpha266_2200 1 None None None 119356749 Common - S-adenosyl-L-homocysteine hydrolase Cpha266_0921 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 119357217 Common hppA membrane-bound proton-translocating pyrophosphatase Cpha266_1408 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 119357853 Common - CRISPR-associated protein Cas1 Cpha266_2061 98 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119355908 Common - protein of unknown function DUF900, hydrolase family protein Cpha266_0058 23 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 119356582 Common - cation diffusion facilitator family transporter Cpha266_0749 197 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 119358195 Common - 30S ribosomal protein S7 Cpha266_2427 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 119356770 Common - protein of unknown function DUF814 Cpha266_0942 59 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 119357918 Common - protein of unknown function DUF1568 Cpha266_2131 48 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 119357667 Nonpathogen - Proto-chlorophyllide reductase 57 kD subunit Cpha266_1871 3 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 119356323 Common - cobalamin (vitamin B12) biosynthesis CbiM protein Cpha266_0486 40 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 119356391 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cpha266_0555 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 119356149 Common - hypothetical protein Cpha266_0307 41 None None None 119356696 Common - heat shock protein Hsp20 Cpha266_0865 158 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 119358181 Common rplN 50S ribosomal protein L14 Cpha266_2413 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 119355861 Common - hypothetical protein Cpha266_0004 8 None None None 119357278 Common - hypothetical protein Cpha266_1471 2 None None None 119358064 Common - trigger factor Cpha266_2292 211 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 119356017 Common - monofunctional biosynthetic peptidoglycan transglycosylase Cpha266_0170 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 119356572 Common - Nitrogenase Cpha266_0738 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 119357682 Common - sigma54 specific transcriptional regulator, Fis family Cpha266_1886 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 119358357 Nonpathogen - hypothetical protein Cpha266_2589 3 None None None 119358257 Common - fatty acid/phospholipid synthesis protein Cpha266_2489 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 119358161 Common - Mannose-1-phosphate guanylyltransferase (GDP) Cpha266_2393 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 119356926 Nonpathogen - hypothetical protein Cpha266_1105 1 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119355991 Common - porphyrin biosynthesis protein, putative Cpha266_0141 121 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 119357165 Common - SMC domain protein Cpha266_1354 136 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 119357808 Common - cell divisionFtsK/SpoIIIE Cpha266_2016 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 119357777 Common - pentapeptide repeat protein Cpha266_1984 51 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 119358480 Common - cell division protein FtsZ Cpha266_2716 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 119355958 Common - ferrous iron transport protein B Cpha266_0108 181 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 119356639 Common - peptidase M23B Cpha266_0808 168 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 119356332 Common - hypothetical protein Cpha266_0495 8 None None None 119357281 Common - hypothetical protein Cpha266_1474 26 None None None 119355868 Common - hypothetical protein Cpha266_0014 5 None None None 119355980 Common - putative glutamate synthase (NADPH) small subunit Cpha266_0130 201 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 119356155 Common - hypothetical protein Cpha266_0313 32 COG3911 COG3911, Predicted ATPase General function prediction only 119356850 Common - putative mitomycin resistance protein Cpha266_1023 11 None None None 119356648 Common - Peptidoglycan glycosyltransferase Cpha266_0817 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 119356837 Common - Prolyl oligopeptidase Cpha266_1010 108 COG1770 PtrB, Protease II Amino acid transport and metabolism 119357865 Common rpmE 50S ribosomal protein L31 Cpha266_2073 195 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 119357434 Common - pseudouridine synthase, RluA family Cpha266_1633 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 119357821 Common valS valyl-tRNA synthetase Cpha266_2029 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119358030 Common - hypothetical protein Cpha266_2258 8 None None None 119357640 Common - hypothetical protein Cpha266_1844 9 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 119357988 Common - hypothetical protein Cpha266_2208 27 COG1106 COG1106, Predicted ATPases General function prediction only 119356830 Common - protein of unknown function DUF134 Cpha266_1003 40 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 119357935 Common - glucose-6-phosphate 1-dehydrogenase Cpha266_2150 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 119356035 Common - coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein Cpha266_0188 35 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 119357884 Common - O-succinylbenzoate-CoA synthase Cpha266_2092 101 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 119358455 Nonpathogen - hypothetical protein Cpha266_2691 2 None None None 119357765 Common - putative transcriptional regulator, GntR family Cpha266_1972 219 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 119356400 Common - phage integrase family protein Cpha266_0564 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119355859 Common - DNA polymerase III, beta subunit Cpha266_0002 209 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 119356891 Nonpathogen - hypothetical protein Cpha266_1070 3 None None None 119358346 Common - glycoside hydrolase, family 3 domain protein Cpha266_2578 177 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 119357598 Common - integral membrane sensor hybrid histidine kinase Cpha266_1801 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 119357056 Common - ABC transporter related Cpha266_1243 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119357507 Common - zinc finger, CHC2-family protein Cpha266_1709 123 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119358077 Common - NAD-dependent epimerase/dehydratase Cpha266_2305 208 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356665 Nonpathogen - hypothetical protein Cpha266_0834 3 None None None 119357288 Common - Integrase, catalytic region Cpha266_1482 62 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 119355881 Common - cytochrome c, class I Cpha266_0031 29 COG2863 COG2863, Cytochrome c553 Energy production and conversion 119356558 Common - hydrogenase expression/formation protein HypD Cpha266_0724 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 119356409 Common - glycine cleavage system H protein Cpha266_0573 184 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 119356859 Common - putative prophage repressor Cpha266_1032 139 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 119357669 Common - GrpE protein Cpha266_1873 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 119357314 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cpha266_1512 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 119356904 Common - Na+/solute symporter Cpha266_1083 129 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 119357300 Nonpathogen - hypothetical protein Cpha266_1496 1 None None None 119356006 Common - short-chain dehydrogenase/reductase SDR Cpha266_0157 222 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 119357820 Common - RNA polymerase, sigma 32 subunit, RpoH Cpha266_2028 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 119358029 Common - hypothetical protein Cpha266_2257 7 None None None 119358037 Nonpathogen - helix-turn-helix domain protein Cpha266_2265 2 COG1395 COG1395, Predicted transcriptional regulator Transcription 119358091 Common - IstB domain protein ATP-binding protein Cpha266_2320 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356093 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_0246 19 COG1146 COG1146, Ferredoxin Energy production and conversion 119356499 Common - PHP C-terminal domain protein Cpha266_0664 136 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 119357413 Common - hypothetical protein Cpha266_1612 5 None None None 119356772 Common - riboflavin biosynthesis protein RibD Cpha266_0944 233 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 119357825 Common - Patatin Cpha266_2033 142 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119357351 Common - PAS/PAC sensor hybrid histidine kinase Cpha266_1549 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119357024 Common - OmpA/MotB domain protein Cpha266_1209 162 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119357878 Common - Heavy metal transport/detoxification protein Cpha266_2086 23 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 119357523 Common - protein of unknown function DUF164 Cpha266_1726 35 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 119358317 Common - phosphoheptose isomerase Cpha266_2549 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 119358209 Common - glycosyl transferase, family 2 Cpha266_2441 142 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119357846 Common - CRISPR-associated protein Cas1 Cpha266_2054 149 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 119356271 Nonpathogen - hypothetical protein Cpha266_0433 3 None None None 119358430 Common - protein of unknown function UPF0079 Cpha266_2666 201 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 119357180 Common - nuclease SbcCD, D subunit Cpha266_1371 101 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 119357340 Common - phosphoesterase, RecJ domain protein Cpha266_1538 83 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 119358198 Common - alkylphosphonate utilization operon protein PhnA Cpha266_2430 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 119358286 Common - peptidase M24 Cpha266_2518 143 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119357809 Common - glycine cleavage system T protein Cpha266_2017 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 119356818 Nonpathogen - hypothetical protein Cpha266_0991 3 None None None 119357459 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Cpha266_1658 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 119357957 Nonpathogen - hypothetical protein Cpha266_2172 2 None None None 119356435 Common - Carbamoyl-phosphate synthetase large chain domain protein Cpha266_0599 233 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 119356471 Common - hypothetical protein Cpha266_0636 36 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 119356291 Common - molybdate ABC transporter, inner membrane subunit Cpha266_0453 206 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 119356068 Common - Dolichyl-phosphate beta-D-mannosyltransferase Cpha266_0221 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119356821 Common - Alcohol dehydrogenase GroES domain protein Cpha266_0994 84 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 119356935 Common - TonB-dependent receptor Cpha266_1115 128 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 119357476 Common - 50S ribosomal protein L25/general stress protein Ctc Cpha266_1675 170 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 119356389 Common - pantoate--beta-alanine ligase Cpha266_0553 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 119358135 Common - hypothetical protein Cpha266_2367 17 None None None 119356875 Common - pentapeptide repeat protein Cpha266_1048 94 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 119357541 Common - transglutaminase, N-terminal domain protein Cpha266_1744 101 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 119355972 Nonpathogen - hypothetical protein Cpha266_0122 5 None None None 119356542 Common - lipoprotein signal peptidase Cpha266_0707 204 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119357102 Nonpathogen - hypothetical protein Cpha266_1289 6 None None None 119356738 Nonpathogen - hypothetical protein Cpha266_0910 3 None None None 119356111 Nonpathogen - hypothetical protein Cpha266_0267 1 None None None 119357449 Nonpathogen - transcriptional regulator, AbrB family Cpha266_1648 7 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 119357893 Common - phospholipase/Carboxylesterase Cpha266_2101 111 COG0400 COG0400, Predicted esterase General function prediction only 119357258 Common - Glycosyltransferase involved in cell wall biogenesis-like protein Cpha266_1450 198 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119357950 Common - peptidase U32 Cpha266_2165 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 119357392 Common - biotin/lipoyl attachment domain-containing protein Cpha266_1591 170 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 119356278 Common - TonB-dependent receptor, putative Cpha266_0440 40 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119356685 Common - dihydroxy-acid dehydratase Cpha266_0854 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 119357193 Common - transposase family protein Cpha266_1384 32 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 119358490 Common - UDP-N-acetylmuramyl-tripeptide synthetases Cpha266_2726 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 119358304 Common - trehalose synthase Cpha266_2536 174 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 119356962 Nonpathogen - exodeoxyribonuclease V, RecC subunit Cpha266_1145 6 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 119356503 Common - Smr protein/MutS2 Cpha266_0668 204 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 119356200 Common - Abortive infection protein Cpha266_0361 20 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 119355944 Common - secretion protein HlyD family protein Cpha266_0094 155 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119356254 Common - translation-associated GTPase Cpha266_0416 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 119357930 Common - protein of unknown function DUF541 Cpha266_2145 74 COG2968 COG2968, Uncharacterized conserved protein Function unknown 119357603 Common - serine O-acetyltransferase Cpha266_1806 211 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 119355951 Common sdhA succinate dehydrogenase flavoprotein subunit Cpha266_0101 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 119357727 Common - NAD-dependent epimerase/dehydratase Cpha266_1931 116 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356182 Common - phage SPO1 DNA polymerase-related protein Cpha266_0343 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 119356596 Common - short-chain dehydrogenase/reductase SDR Cpha266_0764 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 119358125 Common hisG ATP phosphoribosyltransferase Cpha266_2357 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 119357810 Nonpathogen - hypothetical protein Cpha266_2018 1 None None None 119357046 Nonpathogen - hypothetical protein Cpha266_1233 1 None None None 119356139 Common - Tetratricopeptide TPR_2 repeat protein Cpha266_0297 77 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 119357691 Common - Radical SAM domain protein Cpha266_1895 89 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 119356731 Common - Cys/Met metabolism pyridoxal-phosphate-dependent enzymes Cpha266_0903 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 119357811 Nonpathogen - hypothetical protein Cpha266_2019 1 None None None 119357043 Nonpathogen - succinylglutamate desuccinylase/aspartoacylase Cpha266_1229 10 None None None 119357429 Common - inosine-5'-monophosphate dehydrogenase Cpha266_1628 234 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 119356569 Common - transcriptional regulator, ModE family Cpha266_0735 76 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 119356124 Common - Abortive infection protein Cpha266_0281 46 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 119358154 Common chlL protochlorophyllide reductase iron-sulfur ATP-binding protein Cpha266_2386 84 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 119356793 Common - respiratory-chain NADH dehydrogenase, subunit 1 Cpha266_0965 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 119356284 Common - ABC transporter related Cpha266_0446 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119356720 Nonpathogen - hypothetical protein Cpha266_0892 4 None None None 119357328 Common - rfaE bifunctional protein Cpha266_1526 131 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 119357358 Common - IstB domain protein ATP-binding protein Cpha266_1556 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119356483 Common - hypothetical protein Cpha266_0648 17 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119356531 Common - coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein Cpha266_0696 23 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 119358495 Common - hypothetical protein Cpha266_2731 7 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 119357050 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cpha266_1237 179 COG0546 Gph, Predicted phosphatases General function prediction only 119356813 Common - putative esterase Cpha266_0986 66 COG0627 COG0627, Predicted esterase General function prediction only 119357896 Common - cytochrome c family protein Cpha266_2104 19 None None None 119357011 Common - DNA polymerase III, alpha subunit Cpha266_1195 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 119356988 Common - conserved hypothetical protein 103 Cpha266_1171 187 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 119357964 Nonpathogen - hypothetical protein Cpha266_2180 1 None None None 119357966 Common - hypothetical protein Cpha266_2183 21 None None None 119357860 Nonpathogen - hypothetical protein Cpha266_2068 1 None None None 119356519 Common - Pirin domain protein domain protein Cpha266_0684 148 COG1741 COG1741, Pirin-related protein General function prediction only 119357482 Nonpathogen - hypothetical protein Cpha266_1681 2 None None None 119356842 Common - pantetheine-phosphate adenylyltransferase Cpha266_1015 210 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 119355910 Common - transcriptional regulator, TetR family Cpha266_0060 46 COG1309 AcrR, Transcriptional regulator Transcription 119356916 Common - Glucose-6-phosphate isomerase Cpha266_1095 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 119357118 Common - ATP-grasp domain protein Cpha266_1307 204 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 119357497 Common - transposase IS3/IS911 family protein Cpha266_1699 12 None None None 119357422 Nonpathogen - hypothetical protein Cpha266_1621 3 None None None 119357338 Nonpathogen - hypothetical protein Cpha266_1536 12 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 119357146 Common - fumarylacetoacetate (FAA) hydrolase Cpha266_1335 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 119357502 Nonpathogen - hypothetical protein Cpha266_1704 2 COG4637 COG4637, Predicted ATPase General function prediction only 119358102 Common - glycosyl transferase, family 2 Cpha266_2332 174 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119358090 Common - FG-GAP repeat protein Cpha266_2319 158 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119358231 Common - cytochrome c, class I Cpha266_2463 44 COG3245 CycB, Cytochrome c5 Energy production and conversion 119357112 Common - hypothetical protein Cpha266_1300 71 None None None 119358469 Nonpathogen - hypothetical protein Cpha266_2705 1 None None None 119358363 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Cpha266_2595 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 119357591 Common - cytochrome c assembly protein Cpha266_1794 34 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 119355897 Common - Muramoyltetrapeptide carboxypeptidase Cpha266_0047 85 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 119357037 Nonpathogen - hypothetical protein Cpha266_1223 2 None None None 119358170 Common - methionine aminopeptidase, type I Cpha266_2402 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 119356514 Common - enoyl-(acyl-carrier protein) reductase (NADH) Cpha266_0679 195 COG0623 FabI, Enoyl- acyl-carrier-protein 119357516 Nonpathogen - hypothetical protein Cpha266_1718 7 None None None 119355933 Common - DNA-cytosine methyltransferase Cpha266_0083 119 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 119357117 Common - ATP-citrate lyase/succinyl-CoA ligase Cpha266_1306 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 119356712 Common - Redoxin domain protein Cpha266_0884 222 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119358296 Common - alpha/beta hydrolase fold Cpha266_2528 164 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119356726 Nonpathogen - hypothetical protein Cpha266_0898 1 None None None 119356263 Nonpathogen - hypothetical protein Cpha266_0425 8 None None None 119356700 Common - transposase Cpha266_0870 43 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119355938 Nonpathogen - hypothetical protein Cpha266_0088 3 None None None 119358015 Common - hypothetical protein Cpha266_2239 13 None None None 119356703 Common - alanine dehydrogenase/PNT domain protein Cpha266_0875 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 119358269 Common - threonyl-tRNA synthetase Cpha266_2501 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119358168 Common rpmJ 50S ribosomal protein L36 Cpha266_2400 91 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 119357786 Common - UDP-glucose 4-epimerase Cpha266_1993 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 119356025 Common - putative signal-transduction protein with CBS domains Cpha266_0178 115 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 119356088 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Cpha266_0241 109 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 119358409 Nonpathogen - hypothetical protein Cpha266_2645 8 None None None 119356184 Common - hypothetical protein Cpha266_0345 7 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 119356236 Common - surface antigen (D15) Cpha266_0397 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 119356658 Common - glycosyl transferase, family 2 Cpha266_0827 73 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119356589 Nonpathogen - PHP C-terminal domain protein Cpha266_0756 17 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 119356883 Nonpathogen - hypothetical protein Cpha266_1061 1 None None None 119358505 Common - protein of unknown function DUF37 Cpha266_2741 187 COG0759 COG0759, Uncharacterized conserved protein Function unknown 119357139 Common - carboxyl-terminal protease Cpha266_1328 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 119356930 Common - metal dependent phosphohydrolase Cpha266_1109 191 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 119358413 Common - lipopolysaccharide biosynthesis Cpha266_2649 137 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 119356740 Nonpathogen - hypothetical protein Cpha266_0912 2 None None None 119356216 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cpha266_0377 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 119356547 Common - major facilitator superfamily MFS_1 Cpha266_0712 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119358176 Common rplF 50S ribosomal protein L6 Cpha266_2408 229 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 119356240 Common - KpsF/GutQ family protein Cpha266_0401 165 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 119357637 Common - TPR repeat-containing protein Cpha266_1841 191 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 119356866 Common - phosphate ABC transporter, inner membrane subunit PstC Cpha266_1039 224 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 119355965 Common - biotin biosynthesis protein BioC Cpha266_0115 85 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119358197 Nonpathogen - hypothetical protein Cpha266_2429 4 None None None 119357816 Common - excinuclease ABC subunit B Cpha266_2024 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 119358386 Common - transferase hexapeptide repeat containing protein Cpha266_2619 31 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 119358229 Common - hypothetical protein Cpha266_2461 3 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 119356342 Common - dihydropteroate synthase Cpha266_0505 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 119357835 Common - hypothetical protein Cpha266_2043 7 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 119357912 Nonpathogen - hypothetical protein Cpha266_2124 3 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 119355902 Nonpathogen - hypothetical protein Cpha266_0052 1 None None None 119356315 Common - ubiquinone/menaquinone biosynthesis methyltransferases Cpha266_0478 223 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119356116 Common - hypothetical protein Cpha266_0272 2 None None None 119357076 Common - aspartate aminotransferase Cpha266_1263 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119358482 Common - Polypeptide-transport-associated domain protein, FtsQ-type Cpha266_2718 6 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 119358083 Nonpathogen - hypothetical protein Cpha266_2312 3 None None None 119357735 Common - excinuclease ABC, A subunit Cpha266_1939 233 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 119356325 Common - putative transcriptional regulator, CopG family Cpha266_0488 61 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 119358006 Common - hypothetical protein Cpha266_2228 29 None None None 119357136 Common - Argininosuccinate synthase Cpha266_1325 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 119356752 Common - NUDIX hydrolase Cpha266_0924 19 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119356885 Common - biotin/lipoyl attachment domain-containing protein Cpha266_1063 144 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 119357830 Common - hypothetical protein Cpha266_2038 43 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 119358215 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Cpha266_2447 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 119356978 Common - band 7 protein Cpha266_1161 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 119355890 Common - ribonuclease, Rne/Rng family Cpha266_0040 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 119356670 Common - glutamine amidotransferase Cpha266_0839 156 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 119356621 Nonpathogen - hypothetical protein Cpha266_0789 1 None None None 119357156 Nonpathogen - hypothetical protein Cpha266_1345 4 None None None 119357758 Common - peroxiredoxin Cpha266_1965 207 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119358442 Common - ATP-dependent metalloprotease FtsH Cpha266_2678 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 119356679 Common - homoaconitate hydratase family protein Cpha266_0848 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 119356293 Common - modD protein Cpha266_0455 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 119355953 Common - cyclase family protein Cpha266_0103 99 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 119356864 Common - phosphate binding protein Cpha266_1037 183 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 119357542 Nonpathogen - hypothetical protein Cpha266_1745 5 None None None 119358298 Nonpathogen - hypothetical protein Cpha266_2530 1 None None None 119356612 Common - IstB domain protein ATP-binding protein Cpha266_0780 85 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119357712 Common - adenosine deaminase Cpha266_1916 101 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 119356604 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cpha266_0772 8 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 119357320 Common - DNA methylase N-4/N-6 domain protein Cpha266_1518 118 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 119358340 Common - Prephenate dehydrogenase Cpha266_2572 157 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 119355875 Common - transposase Cpha266_0024 31 None None None 119357003 Common - N-acylneuraminate-9-phosphate synthase Cpha266_1187 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 119357745 Common - plasmid maintenance system antidote protein, XRE family Cpha266_1951 30 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 119357698 Common - Ste24 endopeptidase Cpha266_1902 82 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 119357030 Common - hypothetical protein Cpha266_1216 14 COG3905 COG3905, Predicted transcriptional regulator Transcription 119356958 Common - hypothetical protein Cpha266_1141 18 None None None 119356297 Common - hypothetical protein Cpha266_0459 82 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 119356377 Common - CDP-alcohol phosphatidyltransferase Cpha266_0540 193 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 119357632 Common - transposase, IS4 family protein Cpha266_1836 30 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 119358371 Common - putative transcriptional regulator Cpha266_2603 69 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 119358023 Common - hypothetical protein Cpha266_2249 3 None None None 119357273 Common - hypothetical protein Cpha266_1465 35 COG5587 COG5587, Uncharacterized conserved protein Function unknown 119356570 Common - ferredoxin, 2Fe-2S Cpha266_0736 73 COG3411 COG3411, Ferredoxin Energy production and conversion 119358390 Nonpathogen - hypothetical protein Cpha266_2623 1 None None None 119357172 Nonpathogen - hypothetical protein Cpha266_1361 1 None None None 119358240 Nonpathogen - hypothetical protein Cpha266_2472 3 None None None 119358399 Common - polysaccharide biosynthesis protein CapD Cpha266_2635 153 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119356178 Common - protein-L-isoaspartate O-methyltransferase Cpha266_0339 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 119356220 Common - outer membrane chaperone Skp (OmpH) Cpha266_0381 56 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 119358359 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cpha266_2591 188 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 119357650 Common - transcription elongation factor GreA Cpha266_1854 204 COG0782 GreA, Transcription elongation factor Transcription 119356870 Common - phosphate uptake regulator, PhoU Cpha266_1043 46 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 119356465 Nonpathogen - hypothetical protein Cpha266_0630 4 None None None 119357655 Common - GTP-binding protein LepA Cpha266_1859 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 119356774 Common - ABC transporter related Cpha266_0946 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 119356634 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Cpha266_0803 222 COG1049 AcnB, Aconitase B Energy production and conversion 119356301 Common - Rhodanese domain protein Cpha266_0463 92 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119356040 Nonpathogen - hypothetical protein Cpha266_0193 1 None None None 119356095 Common - hypothetical protein Cpha266_0248 29 None None None 119357188 Nonpathogen - helix-turn-helix protein, CopG family Cpha266_1379 5 None None None 119358337 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cpha266_2569 91 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 119356826 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Cpha266_0999 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 119358477 Nonpathogen - hypothetical protein Cpha266_2713 2 None None None 119357666 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Cpha266_1870 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 119357834 Common - IstB domain protein ATP-binding protein Cpha266_2042 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119358275 Nonpathogen - hypothetical protein Cpha266_2507 1 None None None 119356839 Common - PSP1 domain protein Cpha266_1012 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 119356660 Common - Radical SAM domain protein Cpha266_0829 37 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119357231 Nonpathogen - hypothetical protein Cpha266_1423 7 None None None 119357908 Common - hypothetical protein Cpha266_2116 6 COG5428 COG5428, Uncharacterized conserved small protein Function unknown 119358114 Common - lipopolysaccharide biosynthesis Cpha266_2346 37 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119357578 Common - ABC transporter related Cpha266_1781 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 119356762 Common - type III restriction enzyme, res subunit Cpha266_0934 20 None None None 119357683 Common - apolipoprotein N-acyltransferase Cpha266_1887 161 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 119356020 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cpha266_0173 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 119356010 Nonpathogen - hypothetical protein Cpha266_0163 1 None None None 119356698 Nonpathogen - putative transmembrane anti-sigma factor Cpha266_0867 5 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 119356441 Common - Biopolymer transport protein ExbD/TolR Cpha266_0605 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 119357612 Nonpathogen - hypothetical protein Cpha266_1816 9 None None None 119356079 Common rplL 50S ribosomal protein L7/L12 Cpha266_0232 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 119358067 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Cpha266_2295 200 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 119357680 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Cpha266_1884 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 119357994 Nonpathogen - hypothetical protein Cpha266_2215 6 None None None 119356015 Nonpathogen - hypothetical protein Cpha266_0168 1 None None None 119357551 Common - hypothetical protein Cpha266_1754 9 None None None 119357219 Common - alpha/beta hydrolase fold Cpha266_1410 135 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119357240 Common - CRISPR-associated protein Cas4 Cpha266_1432 53 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 119357790 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Cpha266_1997 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 119356152 Nonpathogen - C-type cytochrome, putative Cpha266_0310 2 COG3258 COG3258, Cytochrome c Energy production and conversion 119356434 Nonpathogen - hypothetical protein Cpha266_0598 13 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 119357098 Common - hypothetical protein Cpha266_1285 12 None None None 119358014 Nonpathogen - hypothetical protein Cpha266_2238 5 None None None 119356217 Common - UDP-N-acetylglucosamine diphosphorylase Cpha266_0378 226 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 119356382 Nonpathogen - hypothetical protein Cpha266_0545 1 None None None 119358066 Common - dihydroneopterin aldolase Cpha266_2294 71 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 119358432 Common - chromosome segregation and condensation protein ScpA Cpha266_2668 143 COG1354 COG1354, Uncharacterized conserved protein Function unknown 119357617 Common - glycosyl transferase, family 8 Cpha266_1821 36 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 119356306 Common - Redoxin domain protein Cpha266_0469 141 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119356369 Common - Ribulose-phosphate 3-epimerase Cpha266_0532 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 119358060 Common - putative TIM-barrel protein, nifR3 family Cpha266_2288 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 119356683 Common - acetolactate synthase, small subunit Cpha266_0852 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 119356037 Nonpathogen - hypothetical protein Cpha266_0190 1 None None None 119356053 Common - Na+/solute symporter Cpha266_0206 173 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 119357707 Common - Uncharacterized protein UPF0114 Cpha266_1911 22 COG2862 COG2862, Predicted membrane protein Function unknown 119357704 Common - Type II site-specific deoxyribonuclease Cpha266_1908 5 None None None 119356556 Common - (NiFe) hydrogenase maturation protein HypF Cpha266_0722 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 119356192 Common - ABC transporter related Cpha266_0353 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119357226 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Cpha266_1418 100 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 119358058 Nonpathogen - hypothetical protein Cpha266_2286 3 None None None 119356945 Common - hypothetical protein Cpha266_1125 12 None None None 119358059 Common - aspartate-semialdehyde dehydrogenase Cpha266_2287 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 119356396 Nonpathogen - photosystem P840 reaction center cytochrome c-551 Cpha266_0560 3 None None None 119358262 Common - beta-ketoacyl synthase Cpha266_2494 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119358184 Common rplP 50S ribosomal protein L16 Cpha266_2416 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 119357295 Common - N-6 DNA methylase Cpha266_1491 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 119357753 Common - glutamine amidotransferase class-I Cpha266_1960 126 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 119357620 Common - serine O-acetyltransferase Cpha266_1824 202 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 119358052 Common - Cysteine synthase Cpha266_2280 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 119356173 Common - ATPase AAA-2 domain protein Cpha266_0334 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 119358440 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Cpha266_2676 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 119356070 Common - Phosphopyruvate hydratase Cpha266_0223 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 119356370 Common - surface antigen (D15) Cpha266_0533 100 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 119356330 Common - putative transcriptional regulator Cpha266_0493 152 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 119358380 Common - hypothetical protein Cpha266_2613 10 None None None 119356490 Nonpathogen - hypothetical protein Cpha266_0655 1 None None None 119356667 Common - 3-dehydroquinate synthase Cpha266_0836 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 119356913 Common - hypothetical protein Cpha266_1092 38 None None None 119358372 Nonpathogen - hypothetical protein Cpha266_2604 3 None None None 119356979 Common - UspA domain protein Cpha266_1162 177 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119358330 Common - Formate dehydrogenase Cpha266_2562 188 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 119356470 Common - protein of unknown function DUF1156 Cpha266_0635 41 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 119356909 Common - arsenite-activated ATPase ArsA Cpha266_1088 90 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 119357064 Common - DEAD/DEAH box helicase domain protein Cpha266_1251 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 119358350 Common - phosphoribosylaminoimidazole synthetase Cpha266_2582 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 119357793 Common - short-chain dehydrogenase/reductase SDR Cpha266_2000 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119356229 Common - Holliday junction DNA helicase RuvA Cpha266_0390 206 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair