Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica), complete genome NC_008610 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 118602081 Common - hypothetical protein Rmag_0022 19 None None None 118602892 Common - glycine cleavage system H protein Rmag_0923 184 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 118602328 Common - peptide chain release factor 2 Rmag_0292 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 118602483 Common - rod shape-determining protein RodA Rmag_0471 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 118602468 Common - sigma 54 modulation protein/ribosomal protein S30EA Rmag_0454 114 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 118602154 Common nudE ADP-ribose diphosphatase NudE Rmag_0101 125 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 118602796 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Rmag_0819 202 COG0281 SfcA, Malic enzyme Energy production and conversion 118602112 Common - translation initiation factor IF-2 Rmag_0054 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 118602449 Common - pyridoxamine 5'-phosphate oxidase Rmag_0434 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 118602061 Common - chromosomal replication initiator protein DnaA Rmag_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 118602505 Common - heat shock protein 90 Rmag_0493 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 118602256 Nonpathogen - hypothetical protein Rmag_0213 7 COG3439 COG3439, Uncharacterized conserved protein Function unknown 118602166 Nonpathogen - hypothetical protein Rmag_0114 1 None None None 118602268 Common - ribose 5-phosphate isomerase Rmag_0227 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 118602525 Common - TolB, N-terminal domain protein Rmag_0515 143 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 118603006 Common - ATP synthase F1, gamma subunit Rmag_1046 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 118602299 Common - ribosome recycling factor Rmag_0261 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 118602929 Common - putative integral membrane protein Rmag_0965 68 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 118602291 Common - outer membrane efflux protein Rmag_0253 21 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 118602909 Common - cold-shock DNA-binding domain protein Rmag_0944 183 COG1278 CspC, Cold shock proteins Transcription 118602832 Common - Twin-arginine translocation pathway signal Rmag_0860 159 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 118602794 Common - preprotein translocase, SecE subunit Rmag_0817 14 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 118602135 Common argS arginyl-tRNA synthetase Rmag_0079 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602472 Common aceE pyruvate dehydrogenase subunit E1 Rmag_0458 137 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 118602716 Common - ABC-3 protein Rmag_0732 186 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 118602218 Common - ribosomal protein L22 Rmag_0170 219 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 118602706 Nonpathogen - hypothetical protein Rmag_0718 3 None None None 118603031 Common - Ribulose-phosphate 3-epimerase Rmag_1071 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 118602440 Common - isocitrate dehydrogenase, NADP-dependent Rmag_0423 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 118602320 Common - putative signal-transduction protein with CBS domains Rmag_0283 126 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 118602631 Common - chorismate mutase Rmag_0626 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 118602784 Common - sulfur oxidation protein SoxY-like Rmag_0807 35 COG5501 COG5501, Predicted secreted protein Function unknown 118602767 Common - tRNA/rRNA methyltransferase (SpoU) Rmag_0786 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 118602415 Common - protein of unknown function DUF45 Rmag_0391 151 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 118602238 Common - DNA-directed RNA polymerase, alpha subunit Rmag_0190 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 118602429 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Rmag_0411 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 118602533 Common - ribonucleotide-diphosphate reductase subunit alpha Rmag_0523 208 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 118602884 Common - CMP/dCMP deaminase, zinc-binding Rmag_0915 217 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 118602749 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Rmag_0766 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 118602849 Nonpathogen - heavy metal transport/detoxification protein Rmag_0878 2 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 118602983 Common - PfkB domain protein Rmag_1022 93 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 118602492 Common - poly(A) polymerase Rmag_0480 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 118602190 Common - electron transport complex, RnfABCDGE type, B subunit Rmag_0140 120 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 118602902 Common - glutaredoxin Rmag_0933 86 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 118602666 Common - alanine racemase Rmag_0668 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 118602597 Common - protein of unknown function DUF423 Rmag_0590 44 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 118602711 Common - Biopolymer transport protein ExbD/TolR Rmag_0724 135 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 118602177 Common - BolA family protein Rmag_0126 21 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 118602066 Common - dihydroorotate dehydrogenase family protein Rmag_0006 166 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 118602240 Common - ribosomal protein S21 Rmag_0192 114 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 118602457 Common - tRNA-dihydrouridine synthase A Rmag_0442 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 118602686 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Rmag_0690 127 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 118602957 Common pyrE orotate phosphoribosyltransferase Rmag_0995 143 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 118602187 Common - dihydropteroate synthase Rmag_0137 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 118602877 Common - O-antigen polymerase Rmag_0908 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 118602942 Common - putative metalloendopeptidase, glycoprotease family Rmag_0980 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 118602535 Common - ferredoxin Rmag_0525 24 COG0633 Fdx, Ferredoxin Energy production and conversion 118602435 Common - nitrogen-fixing NifU domain protein Rmag_0417 54 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 118602499 Common - phospholipid/glycerol acyltransferase Rmag_0487 173 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 118602140 Common - sulfate adenylyltransferase Rmag_0085 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 118602289 Common - glycosyl hydrolase, BNR repeat-containing protein Rmag_0251 109 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 118602926 Common - catalytic domain of components of various dehydrogenase complexes Rmag_0962 197 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 118602459 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Rmag_0444 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 118602121 Common - Phosphoglycerate kinase Rmag_0065 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 118602829 Common - protein of unknown function UPF0079 Rmag_0856 183 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 118602390 Common - response regulator receiver protein Rmag_0362 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 118602760 Common - peptidase M16 domain protein Rmag_0777 173 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 118602673 Common - ABC transporter related Rmag_0676 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 118602261 Common - aminotransferase, class IV Rmag_0218 136 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 118602090 Nonpathogen - hypothetical protein Rmag_0031 1 None None None 118602911 Common - Exodeoxyribonuclease I Rmag_0946 53 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 118602702 Common - putative iron-regulated protein A Rmag_0712 31 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 118603029 Common - GTP-binding protein YchF Rmag_1069 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 118602507 Common - coproporphyrinogen III oxidase Rmag_0496 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 118602388 Common - Inorganic diphosphatase Rmag_0356 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 118602565 Common - integral membrane protein MviN Rmag_0557 181 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 118603000 Common - 60 kDa inner membrane insertion protein Rmag_1040 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 118602427 Common - delta-aminolevulinic acid dehydratase Rmag_0409 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 118602977 Common - glutamate--cysteine ligase Rmag_1015 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 118602847 Common - VacJ family lipoprotein Rmag_0876 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 118602392 Common - potassium uptake protein, TrkH family Rmag_0364 121 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 118602330 Common - lipid A biosynthesis acyltransferase Rmag_0294 101 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 118602952 Common - ribosomal protein S16 Rmag_0990 205 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 118602543 Common - HflC protein Rmag_0533 206 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 118602787 Common - DNA-directed RNA polymerase, beta' subunit Rmag_0810 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 118602615 Nonpathogen - hypothetical protein Rmag_0609 1 None None None 118602614 Common - ubiquinone biosynthesis O-methyltransferase Rmag_0608 160 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 118602681 Common - molybdopterin oxidoreductase Rmag_0685 180 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 118602866 Common - hypothetical protein Rmag_0896 9 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 118602924 Common - ABC-2 type transporter Rmag_0960 146 COG1511 COG1511, Predicted membrane protein Function unknown 118602430 Common - small GTP-binding protein Rmag_0412 249 COG0536 Obg, Predicted GTPase General function prediction only 118602769 Common - electron transport complex, RnfABCDGE type, E subunit Rmag_0788 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 118602515 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Rmag_0505 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 118602574 Common - beta-ketoacyl synthase Rmag_0566 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 118602734 Common - peptidase M23B Rmag_0751 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 118603021 Common - N-acetyl-gamma-glutamyl-phosphate reductase Rmag_1061 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 118602853 Common - alanyl-tRNA synthetase Rmag_0882 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602100 Common - cytochrome c oxidase, cbb3-type, subunit III Rmag_0041 68 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 118602991 Common - UDP-N-acetylglucosamine pyrophosphorylase Rmag_1030 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 118602623 Common - transcriptional regulator, ArsR family Rmag_0618 146 COG0640 ArsR, Predicted transcriptional regulators Transcription 118602931 Common - peptide deformylase Rmag_0967 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 118602308 Common - uroporphyrin-III C-methyltransferase Rmag_0270 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 118602585 Common - transcriptional regulator, BadM/Rrf2 family Rmag_0578 159 COG1959 COG1959, Predicted transcriptional regulator Transcription 118602816 Common - tetraacyldisaccharide 4'-kinase Rmag_0843 125 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 118602231 Common - ribosomal protein L30 Rmag_0183 115 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 118602762 Common - signal recognition particle-docking protein FtsY Rmag_0781 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 118602172 Common - protein of unknown function UPF0054 Rmag_0121 201 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 118602209 Common - 30S ribosomal protein S7 Rmag_0161 243 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 118602353 Nonpathogen - hypothetical protein Rmag_0319 2 None None None 118602691 Common - molybdenum cofactor synthesis domain Rmag_0698 132 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 118602655 Nonpathogen - hypothetical protein Rmag_0655 1 None None None 118602200 Common - Argininosuccinate synthase Rmag_0151 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 118602840 Common - DsrE family protein Rmag_0868 46 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 118602557 Common apaH diadenosine tetraphosphatase Rmag_0549 102 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 118602403 Common - cyclase/dehydrase Rmag_0378 100 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 118602223 Common - ribosomal protein L14 Rmag_0175 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 118602461 Common - acetolactate synthase, small subunit Rmag_0446 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 118602595 Nonpathogen - hypothetical protein Rmag_0588 5 None None None 118602862 Common - hypothetical protein Rmag_0892 5 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 118602834 Common - putative glutamate synthase (NADPH) small subunit Rmag_0862 191 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 118602149 Common - 6-phosphofructokinase Rmag_0094 144 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 118602989 Common - heavy metal translocating P-type ATPase Rmag_1028 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 118602907 Common - Redoxin domain protein Rmag_0939 58 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 118602293 Common - ABC transporter related Rmag_0255 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 118602063 Common - DNA gyrase, B subunit Rmag_0003 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 118602782 Common - sulfur oxidation protein SoxA Rmag_0805 25 COG3258 COG3258, Cytochrome c Energy production and conversion 118602757 Common - conserved hypothetical protein 701 Rmag_0774 94 COG1981 COG1981, Predicted membrane protein Function unknown 118602216 Common rplB 50S ribosomal protein L2 Rmag_0168 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 118602278 Common - NADH dehydrogenase subunit D Rmag_0240 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 118602696 Common - binding-protein-dependent transport systems inner membrane component Rmag_0705 191 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 118602725 Common - hypothetical protein Rmag_0741 62 COG1238 COG1238, Predicted membrane protein Function unknown 118602485 Common - Sel1 domain protein repeat-containing protein Rmag_0473 88 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 118602894 Common - Intracellular septation protein A Rmag_0925 61 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 118602446 Common - chorismate synthase Rmag_0430 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 118602368 Common - Citrate transporter Rmag_0336 51 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 118602108 Common - CrcB protein Rmag_0050 39 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 118602152 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Rmag_0098 225 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 118602579 Common - ferredoxin, 2Fe-2S type, ISC system Rmag_0572 57 COG0633 Fdx, Ferredoxin Energy production and conversion 118602651 Common - hypothetical protein Rmag_0650 10 None None None 118602531 Common - hypothetical protein Rmag_0521 10 None None None 118602408 Nonpathogen - hypothetical protein Rmag_0383 1 None None None 118603011 Common - F0F1 ATP synthase subunit A Rmag_1051 157 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 118602284 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Rmag_0246 107 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 118602070 Common - Cytochrome b/b6, N-terminal domain Rmag_0010 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 118602510 Common - biotin synthase Rmag_0499 184 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 118602837 Common - DsrC family protein Rmag_0865 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 118602738 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Rmag_0755 194 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 118602326 Common - Phosphoribosyl-AMP cyclohydrolase Rmag_0289 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 118602099 Common - cytochrome c oxidase, cbb3-type, subunit II Rmag_0040 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 118602079 Common - aminotransferase, class I and II Rmag_0020 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 118602940 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Rmag_0977 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 118602912 Common - endonuclease III Rmag_0947 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 118602455 Common - aminopeptidase N Rmag_0440 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 118602920 Common - DSBA oxidoreductase Rmag_0955 67 None None None 118602179 Common - hypothetical protein Rmag_0128 3 None None None 118602242 Common - Polynucleotide adenylyltransferase region Rmag_0197 138 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 118602590 Common - Shikimate kinase Rmag_0583 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 118602871 Common - polysaccharide biosynthesis protein Rmag_0901 40 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 118602092 Common - hypothetical protein Rmag_0033 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 118602142 Common - adenylylsulfate reductase, beta subunit Rmag_0087 29 COG1146 COG1146, Ferredoxin Energy production and conversion 118602809 Common - alpha/beta hydrolase fold Rmag_0836 51 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 118602123 Common - fructose-bisphosphate aldolase, class II, Calvin cycle subtype Rmag_0067 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 118602500 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Rmag_0488 169 COG0546 Gph, Predicted phosphatases General function prediction only 118603018 Common - 3-dehydroquinate dehydratase, type II Rmag_1058 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 118602538 Common - GCN5-related N-acetyltransferase Rmag_0528 83 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 118602981 Common - maf protein Rmag_1020 175 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 118602236 Common - 30S ribosomal protein S11 Rmag_0188 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 118602572 Common - exsB protein Rmag_0564 175 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 118602878 Common - glutaminyl-tRNA synthetase Rmag_0909 238 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 118602413 Common - methyltransferase small Rmag_0388 80 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 118602963 Common - amidophosphoribosyltransferase Rmag_1001 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 118602765 Common - argininosuccinate lyase Rmag_0784 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 118602708 Common - Glycine--tRNA ligase Rmag_0721 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 118602106 Common - lytic murein transglycosylase Rmag_0047 106 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 118602755 Common cysM cysteine synthase B Rmag_0772 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 118602630 Common - histidinol-phosphate aminotransferase Rmag_0625 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 118602886 Common - malonyl CoA-acyl carrier protein transacylase Rmag_0917 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 118602312 Common - succinyl-diaminopimelate desuccinylase Rmag_0274 204 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 118602258 Common - putative nitrogen regulatory protein P-II family protein Rmag_0215 20 None None None 118602300 Common - uridylate kinase Rmag_0262 240 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 118602785 Common - hypothetical protein Rmag_0808 9 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 118602684 Common - nitrite reductase (NAD(P)H), large subunit Rmag_0688 187 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 118602247 Common - cytochrome c, class I Rmag_0203 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 118602086 Common - undecaprenyl diphosphate synthase Rmag_0027 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 118602077 Common - homoserine O-succinyltransferase Rmag_0018 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 118602657 Common - cytochrome c-type biogenesis protein CcmE Rmag_0659 97 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 118602818 Common - ABC transporter related Rmag_0845 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 118602647 Common rpmI 50S ribosomal protein L35 Rmag_0646 167 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 118602432 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Rmag_0414 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 118602437 Common - thiamine-monophosphate kinase Rmag_0419 193 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 118602365 Common - formamidopyrimidine-DNA glycosylase Rmag_0332 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 118602775 Common - Peptidoglycan glycosyltransferase Rmag_0797 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 118602466 Common - ornithine carbamoyltransferase Rmag_0452 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 118602864 Common - methyltransferase FkbM Rmag_0894 25 None None None 118602640 Common - protein of unknown function UPF0118 Rmag_0639 22 COG0628 PerM, Predicted permease General function prediction only 118602951 Common - 16S rRNA processing protein RimM Rmag_0989 145 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 118602110 Common - protein of unknown function DUF150 Rmag_0052 175 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 118602914 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Rmag_0949 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 118602520 Common - single-strand binding protein Rmag_0510 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 118602517 Common - NusB antitermination factor Rmag_0507 135 COG0781 NusB, Transcription termination factor Transcription 118602527 Common - Tetratricopeptide TPR_2 repeat protein Rmag_0517 49 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 118602509 Common - glutamine synthetase, type I Rmag_0498 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 118603027 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Rmag_1067 188 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 118602625 Common - carboxyl-terminal protease Rmag_0620 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 118602608 Common - ATP phosphoribosyltransferase Rmag_0601 209 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 118602650 Common - single-stranded-DNA-specific exonuclease RecJ Rmag_0649 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 118602563 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Rmag_0555 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 118602463 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Rmag_0448 153 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 118602545 Common - Organic solvent tolerance protein Rmag_0535 100 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 118602355 Nonpathogen - hypothetical protein Rmag_0321 3 None None None 118602332 Common - Peptidoglycan glycosyltransferase Rmag_0296 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 118602119 Common - transketolase Rmag_0062 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 118602401 Common - ribonuclease H Rmag_0374 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 118602842 Common - sulfite reductase, dissimilatory-type alpha subunit Rmag_0870 30 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 118602494 Common - Polyprenyl synthetase Rmag_0482 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 118602693 Common - CbbQ/NirQ/NorQ C-terminal domain protein Rmag_0700 101 COG0714 COG0714, MoxR-like ATPases General function prediction only 118602202 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Rmag_0153 213 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 118602998 Common - ribonuclease P protein component Rmag_1038 32 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 118602610 Common - signal recognition particle protein Rmag_0604 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 118602555 Common - dimethyladenosine transferase Rmag_0547 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 118602263 Common - ATPase Rmag_0221 137 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 118602282 Common - respiratory-chain NADH dehydrogenase, subunit 1 Rmag_0244 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 118602251 Common - small GTP-binding protein Rmag_0207 218 COG2262 HflX, GTPases General function prediction only 118602612 Common - GTP-binding protein LepA Rmag_0606 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 118602346 Common - Alanine--glyoxylate transaminase Rmag_0312 157 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 118602314 Common - nitrogen regulatory protein P-II Rmag_0276 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 118602228 Common - ribosomal protein L6 Rmag_0180 232 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 118602938 Common - CBS domain containing protein Rmag_0975 222 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 118602174 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Rmag_0123 187 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 118602158 Common - nicotinate-nucleotide pyrophosphorylase Rmag_0106 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 118602851 Common - hypothetical protein Rmag_0880 26 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 118602377 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Rmag_0345 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 118602181 Nonpathogen - hypothetical protein Rmag_0130 1 None None None 118602088 Common - putative transmembrane protein Rmag_0029 21 None None None 118602306 Common - Chromosomal replication initiator, DnaA Rmag_0268 104 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 118602676 Common - Lytic transglycosylase, catalytic Rmag_0679 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 118602444 Common - Radical SAM domain protein Rmag_0427 172 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 118602619 Common - Ribonuclease III Rmag_0614 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 118603012 Nonpathogen - hypothetical protein Rmag_1052 1 None None None 118602583 Common - scaffold protein Rmag_0576 153 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 118602424 Common - DNA polymerase III, epsilon subunit Rmag_0404 191 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 118602337 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Rmag_0303 108 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 118602916 Common - aspartate-semialdehyde dehydrogenase Rmag_0951 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 118602810 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Rmag_0837 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 118602294 Common - secretion protein HlyD family protein Rmag_0256 133 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 118602536 Common - putative dUTPase Rmag_0526 11 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 118602812 Common - glutaredoxin Rmag_0839 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 118602411 Common - deoxyxylulose-5-phosphate synthase Rmag_0386 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 118602936 Common - peptidase U62, modulator of DNA gyrase Rmag_0973 154 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 118602439 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Rmag_0421 101 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 118602570 Common - chaperonin GroEL Rmag_0562 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 118602638 Common - hypothetical protein Rmag_0637 29 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 118602905 Common rplM 50S ribosomal protein L13 Rmag_0936 235 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 118602188 Common - phosphoglucosamine mutase Rmag_0138 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 118602745 Common - Lytic transglycosylase, catalytic Rmag_0762 144 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 118602375 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Rmag_0343 114 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 118602194 Nonpathogen - hypothetical protein Rmag_0144 6 None None None 118602918 Common - histidinol-phosphate aminotransferase Rmag_0953 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 118602104 Common - aspartate carbamoyltransferase Rmag_0045 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 118602626 Common - signal peptidase I Rmag_0621 211 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 118602889 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Rmag_0920 180 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 118602168 Common - pyrroline-5-carboxylate reductase Rmag_0116 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 118602244 Common - GTP-binding Rmag_0200 179 COG0218 COG0218, Predicted GTPase General function prediction only 118603003 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family Rmag_1043 107 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 118602750 Common - protein of unknown function UPF0005 Rmag_0767 108 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 118602821 Common - pyruvate carboxylase subunit B Rmag_0848 201 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 118602452 Common - short-chain dehydrogenase/reductase SDR Rmag_0437 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 118602497 Common - ribosomal protein L32 Rmag_0485 99 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 118602987 Common - uroporphyrinogen decarboxylase Rmag_1026 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 118602824 Common - 5,10-methylenetetrahydrofolate reductase Rmag_0851 139 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 118602317 Common - NlpBDapX lipoprotein Rmag_0279 27 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 118602144 Nonpathogen - hypothetical protein Rmag_0089 4 None None None 118602687 Common - molybdenum cofactor synthesis domain Rmag_0691 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 118602860 Common - glycosyl transferase, group 1 Rmag_0890 139 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 118602343 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Rmag_0309 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 118602966 Common - beta-ketoacyl synthase Rmag_1004 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 118602265 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Rmag_0223 74 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 118602947 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Rmag_0985 140 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 118602150 Common - hypothetical protein Rmag_0095 2 None None None 118602138 Nonpathogen - protein of unknown function DUF1239 Rmag_0083 1 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 118602358 Common - arsenate reductase Rmag_0324 117 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 118602464 Common - 2-isopropylmalate synthase Rmag_0449 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 118602807 Common thiG thiazole synthase Rmag_0834 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 118602252 Common - ATP-dependent protease La Rmag_0208 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 118602487 Common - UTP-GlnB uridylyltransferase, GlnD Rmag_0475 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 118602324 Common - twin-arginine translocation protein, TatA/E family subunit Rmag_0287 4 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 118602831 Nonpathogen - Polysulphide reductase, NrfD Rmag_0859 21 COG5557 COG5557, Polysulphide reductase Energy production and conversion 118602897 Common - DEAD/DEAH box helicase domain protein Rmag_0928 217 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 118602131 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Rmag_0075 79 COG0348 NapH, Polyferredoxin Energy production and conversion 118602132 Nonpathogen - hypothetical protein Rmag_0076 2 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 118602641 Nonpathogen - hypothetical protein Rmag_0640 1 None None None 118602598 Common - histone family protein DNA-binding protein Rmag_0591 176 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 118602069 Common - ubiquinol-cytochrome c reductase cytochrome c1 subunit Rmag_0009 52 COG2857 CYT1, Cytochrome c1 Energy production and conversion 118602978 Common - hypothetical protein Rmag_1016 187 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 118602529 Common - multiple antibiotic resistance (MarC)-related proteins Rmag_0519 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 118602276 Common - NADH-quinone oxidoreductase, B subunit Rmag_0238 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 118602705 Common - hypothetical protein Rmag_0717 111 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 118602076 Common - riboflavin biosynthesis protein RibF Rmag_0016 211 COG0196 RibF, FAD synthase Coenzyme metabolism 118602581 Common - co-chaperone Hsc20 Rmag_0574 56 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 118602366 Common - membrane protein-like Rmag_0333 28 COG3748 COG3748, Predicted membrane protein Function unknown 118602933 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Rmag_0969 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 118602159 Common - inositol monophosphatase Rmag_0107 184 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 118602973 Common - Rhodanese domain protein Rmag_1011 64 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 118602249 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Rmag_0205 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 118602398 Common - 3-isopropylmalate dehydratase, small subunit Rmag_0371 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 118602489 Common rho transcription termination factor Rho Rmag_0477 206 COG1158 Rho, Transcription termination factor Transcription 118602857 Common - polysaccharide biosynthesis protein CapD Rmag_0886 150 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 118602727 Common - tRNA-i(6)A37 thiotransferase enzyme MiaB Rmag_0743 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 118602513 Common - ABC transporter related Rmag_0502 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 118602558 Common - Diaminopimelate epimerase Rmag_0550 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 118602259 Common - protein of unknown function DUF1538 Rmag_0216 23 None None None 118602285 Common - NADH-ubiquinone oxidoreductase, chain 4L Rmag_0247 161 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 118602975 Common - signal transduction histidine kinase, nitrate/nitrite-specific, NarQ Rmag_1013 145 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 118602270 Common - acetylglutamate kinase Rmag_0232 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 118602752 Common - Homoserine dehydrogenase Rmag_0769 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 118602780 Common - DNA polymerase III, alpha subunit Rmag_0803 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 118602935 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Rmag_0972 139 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 118602637 Common - peptide methionine sulfoxide reductase Rmag_0636 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 118602589 Common - Outer membrane protein-like Rmag_0582 5 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 118602386 Common - pantetheine-phosphate adenylyltransferase Rmag_0354 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 118602341 Common - peptide chain release factor 3 Rmag_0307 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 118602426 Nonpathogen - hypothetical protein Rmag_0408 1 None None None 118603025 Nonpathogen - hypothetical protein Rmag_1065 2 None None None 118602662 Common - ribosomal protein S6 Rmag_0664 174 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 118602339 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Rmag_0305 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 118602511 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Rmag_0500 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 118603010 Common - F0F1 ATP synthase subunit C Rmag_1050 67 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 118602254 Common - thiol-disulfide interchange protein DsbC Rmag_0210 61 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 118603017 Common - Protein-disulfide reductase Rmag_1057 164 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 118602199 Common - Sel1 domain protein repeat-containing protein Rmag_0149 99 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 118602222 Common - ribosomal protein S17 Rmag_0174 236 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 118602518 Nonpathogen - hypothetical protein Rmag_0508 1 None None None 118602740 Common - UDP-N-acetylmuramate--alanine ligase Rmag_0757 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 118602721 Common - heme exporter protein CcmB Rmag_0737 78 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 118602996 Common - protein of unknown function DUF494 Rmag_1035 38 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 118602601 Common - lysyl-tRNA synthetase Rmag_0594 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 118602695 Common - arginine biosynthesis bifunctional protein ArgJ Rmag_0704 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 118602219 Common - ribosomal protein S3 Rmag_0171 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 118602593 Nonpathogen - hypothetical protein Rmag_0586 1 None None None 118602921 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Rmag_0956 41 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 118602163 Common - oligoribonuclease Rmag_0111 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 118602334 Common - S-adenosyl-methyltransferase MraW Rmag_0298 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 118603004 Common - ATP synthase F1, epsilon subunit Rmag_1044 172 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 118602644 Common - phenylalanyl-tRNA synthetase, alpha subunit Rmag_0643 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 118602084 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Rmag_0025 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 118602618 Common - GTP-binding protein Era Rmag_0613 221 COG1159 Era, GTPase General function prediction only 118602839 Common - DsrE family protein Rmag_0867 39 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 118602502 Common - short-chain dehydrogenase/reductase SDR Rmag_0490 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 118602606 Common - toluene tolerance family protein Rmag_0599 21 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 118602771 Common - hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit Rmag_0793 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 118602843 Common - glutamate synthases, NADH/NADPH, small subunit Rmag_0871 191 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 118602569 Common - chaperonin Cpn10 Rmag_0561 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 118602477 Common - valyl-tRNA synthetase Rmag_0464 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118603036 Common - Triose-phosphate isomerase Rmag_1076 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 118602777 Common - riboflavin biosynthesis protein RibD Rmag_0800 230 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 118602758 Nonpathogen - hypothetical protein Rmag_0775 1 None None None 118602361 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Rmag_0327 151 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 118603014 Common - NAD(+) kinase Rmag_1054 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 118602620 Nonpathogen - hypothetical protein Rmag_0615 6 None None None 118602995 Common - DNA topoisomerase I Rmag_1034 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 118602958 Common - exodeoxyribonuclease III Rmag_0996 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 118602801 Common - beta-lactamase domain protein Rmag_0826 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 118602093 Common - Cytochrome-c oxidase Rmag_0034 151 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 118602097 Common - hypothetical protein Rmag_0038 52 COG3346 COG3346, Uncharacterized conserved protein Function unknown 118602678 Common - thioredoxin, putative Rmag_0682 58 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 118602246 Common - cytochrome c4 precursor Rmag_0202 28 COG2863 COG2863, Cytochrome c553 Energy production and conversion 118602701 Common - protein of unknown function DUF1111 Rmag_0711 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 118602823 Common - translation initiation factor IF-1 Rmag_0850 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 118602379 Common - peptidase M50 Rmag_0347 78 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 118602713 Nonpathogen - hypothetical protein Rmag_0729 1 None None None 118602872 Common - NAD-dependent epimerase/dehydratase Rmag_0902 212 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 118602128 Common - pseudouridine synthase, RluA family Rmag_0072 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 118602964 Common - O-succinylhomoserine sulfhydrylase Rmag_1002 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 118602136 Common - UvrD/REP helicase Rmag_0080 221 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 118602945 Common - diacylglycerol kinase Rmag_0983 107 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 118602718 Common - SmpA/OmlA domain protein Rmag_0734 43 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 118603033 Common - translation elongation factor Ts Rmag_1073 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 118602627 Common - DsrC family protein Rmag_0622 58 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 118602287 Common - proton-translocating NADH-quinone oxidoreductase, chain M Rmag_0249 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 118602146 Nonpathogen - hypothetical protein Rmag_0091 2 None None None 118602185 Nonpathogen - hypothetical protein Rmag_0135 1 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 118602805 Common - Indole-3-glycerol-phosphate synthase Rmag_0832 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 118602553 Common - efflux transporter, RND family, MFP subunit Rmag_0545 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 118602428 Common - thiamine biosynthesis protein ThiC Rmag_0410 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 118602985 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Rmag_1024 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 118602747 Common - oxidoreductase FAD/NAD(P)-binding domain protein Rmag_0764 147 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 118602636 Common - UBA/THIF-type NAD/FAD binding protein Rmag_0635 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 118602875 Common - hypothetical protein Rmag_0905 14 None None None 118602233 Common - preprotein translocase, SecY subunit Rmag_0185 221 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 118602124 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Rmag_0068 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 118602732 Common - ribosomal protein S20 Rmag_0749 192 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 118602214 Common - ribosomal protein L4/L1e Rmag_0166 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 118602372 Common - isoleucyl-tRNA synthetase Rmag_0340 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602664 Common - ribosomal protein L9 Rmag_0666 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 118602192 Common - electron transport complex, RnfABCDGE type, D subunit Rmag_0142 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 118602373 Common - 3-dehydroquinate synthase Rmag_0341 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 118602826 Common - Uroporphyrinogen III synthase HEM4 Rmag_0853 69 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 118602976 Common - tRNA modification GTPase TrmE Rmag_1014 225 COG0486 ThdF, Predicted GTPase General function prediction only 118602074 Common anmK anhydro-N-acetylmuramic acid kinase Rmag_0014 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 118602729 Common - protein of unknown function DUF461 Rmag_0745 52 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 118602274 Common - peptidase U62, modulator of DNA gyrase Rmag_0236 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 118602364 Nonpathogen - putative prophage repressor Rmag_0331 4 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 118602480 Common - aminoglycoside phosphotransferase Rmag_0468 92 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 118602280 Common - NADH-quinone oxidoreductase, F subunit Rmag_0242 170 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 118602779 Nonpathogen - hypothetical protein Rmag_0802 1 None None None 118602723 Common - S-adenosyl-L-homocysteine hydrolase Rmag_0739 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 118602768 Common - ATPase AAA-2 domain protein Rmag_0787 219 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 118602418 Common - quinolinate synthetase Rmag_0395 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 118602064 Common - Phosphoribulokinase Rmag_0004 67 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 118602556 Common apaG ApaG Rmag_0548 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 118602290 Nonpathogen - hypothetical protein Rmag_0252 1 None None None 118602296 Common - periplasmic solute binding protein Rmag_0258 65 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 118602930 Common - L-aspartate oxidase Rmag_0966 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 118602707 Common - hypothetical protein Rmag_0719 3 None None None 118602971 Common - Rhodanese domain protein Rmag_1009 91 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 118602575 Nonpathogen - hypothetical protein Rmag_0567 1 None None None 118602322 Common - Sec-independent protein translocase, TatC subunit Rmag_0285 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 118602899 Common - putative methyltransferase Rmag_0930 52 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 118602880 Common - ATPase AAA-2 domain protein Rmag_0911 219 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 118602890 Common - UDP-2,3-diacylglucosamine hydrolase Rmag_0921 73 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 118602157 Common - lipid-A-disaccharide synthase Rmag_0105 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 118602164 Common - anthranilate phosphoribosyltransferase Rmag_0112 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 118603008 Common - ATP synthase F1, delta subunit Rmag_1048 161 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 118602490 Common - permease YjgP/YjgQ family protein Rmag_0478 63 COG0795 COG0795, Predicted permeases General function prediction only 118602450 Common - shikimate 5-dehydrogenase Rmag_0435 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 118602656 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Rmag_0656 166 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 118603001 Common - hypothetical protein Rmag_1041 6 None None None 118602742 Common - D-alanine--D-alanine ligase Rmag_0759 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 118602697 Common - extracellular solute-binding protein, family 1 Rmag_0706 119 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 118602206 Common - KpsF/GutQ family protein Rmag_0158 163 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 118602348 Common - FAD/FMN-containing dehydrogenases-like Rmag_0314 119 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 118602217 Common - ribosomal protein S19 Rmag_0169 247 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 118602197 Common - translation elongation factor P Rmag_0147 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 118602969 Common - preprotein translocase, YajC subunit Rmag_1007 114 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 118602220 Common rplP 50S ribosomal protein L16 Rmag_0172 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 118602207 Common - protein tyrosine phosphatase Rmag_0159 112 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 118602354 Common - UvrD/REP helicase Rmag_0320 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 118602679 Common - uracil-DNA glycosylase Rmag_0683 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 118602791 Common - ribosomal protein L1 Rmag_0814 249 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 118602319 Common - nitrogen regulatory protein P-II Rmag_0281 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 118602171 Common - primosomal protein N' Rmag_0120 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 118603023 Common - methylcitrate synthase Rmag_1063 193 COG0372 GltA, Citrate synthase Energy production and conversion 118602310 Common - cytochrome c-type biogenesis protein CcmF Rmag_0272 138 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 118602352 Common - Beta-N-acetylhexosaminidase Rmag_0318 170 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 118602660 Common - peptidase M22, glycoprotease Rmag_0662 156 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 118602634 Common - Ribonucleotide reductase regulator NrdR-like Rmag_0631 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 118602672 Common - CTP synthetase Rmag_0674 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 118602298 Nonpathogen - hypothetical protein Rmag_0260 1 None None None 118602405 Common - histone family protein DNA-binding protein Rmag_0380 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 118602384 Common - chaperone protein DnaJ Rmag_0352 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 118602587 Common - lipid A biosynthesis acyltransferase Rmag_0580 95 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 118602448 Common - hypothetical protein Rmag_0433 113 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 118602577 Common - methionyl-tRNA synthetase Rmag_0570 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602305 Common - CDP-alcohol phosphatidyltransferase Rmag_0267 183 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 118602797 Common - glycine dehydrogenase Rmag_0821 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 118602540 Common - ribonuclease R Rmag_0530 192 COG0557 VacB, Exoribonuclease R Transcription 118602479 Common - Nucleotidyl transferase Rmag_0467 210 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 118602549 Common - protein of unknown function DUF493 Rmag_0541 21 COG2921 COG2921, Uncharacterized conserved protein Function unknown 118602622 Common - prolipoprotein diacylglyceryl transferase Rmag_0617 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 118602653 Common - lipoprotein signal peptidase Rmag_0652 185 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 118602869 Common - hypothetical protein Rmag_0899 6 None None None 118602391 Common trkA potassium transporter peripheral membrane component Rmag_0363 146 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 118602072 Nonpathogen - hypothetical protein Rmag_0012 1 None None None 118602225 Common rplE 50S ribosomal protein L5 Rmag_0177 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 118602910 Nonpathogen - hypothetical protein Rmag_0945 1 None None None 118602470 Common - Phosphomannomutase Rmag_0456 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 118602993 Common - Phosphoribosylanthranilate isomerase Rmag_1032 198 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 118602522 Common - putative transmembrane protein Rmag_0512 121 COG4105 ComL, DNA uptake lipoprotein General function prediction only 118602095 Common - cytochrome c oxidase assembly protein CtaG/Cox11 Rmag_0036 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 118602736 Nonpathogen - hypothetical protein Rmag_0753 1 None None None 118602272 Common - Protein of unknown function UPF0001 Rmag_0234 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 118602885 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Rmag_0916 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 118602604 Common - hypothetical protein Rmag_0597 26 None None None 118602855 Common - glucose-6-phosphate isomerase Rmag_0884 200 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 118602114 Common - tRNA pseudouridine synthase B Rmag_0056 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 118602567 Common - Guanylate kinase Rmag_0559 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 118602395 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Rmag_0367 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 118602381 Common - phosphatidylserine decarboxylase Rmag_0349 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 118602646 Common - ribosomal protein L20 Rmag_0645 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 118602955 Common - ribosomal protein L33 Rmag_0993 138 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 118602923 Common - protein of unknown function DUF205 Rmag_0958 170 COG0344 COG0344, Predicted membrane protein Function unknown 118602336 Common - DNA topoisomerase IV subunit A Rmag_0302 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 118602629 Common - Prephenate dehydrogenase Rmag_0624 160 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 118602845 Common - transcription elongation factor GreA Rmag_0874 202 COG0782 GreA, Transcription elongation factor Transcription 118602773 Common - rod shape-determining protein MreC Rmag_0795 142 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 118602443 Common - excinuclease ABC subunit B Rmag_0426 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 118602504 Common - RNA methyltransferase, TrmH family, group 1 Rmag_0492 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 118602560 Common - putative membrane-associated zinc metalloprotease Rmag_0552 212 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 118602948 Common - transcriptional regulator, LysR family Rmag_0986 190 COG0583 LysR, Transcriptional regulator Transcription 118602561 Common - surface antigen (D15) Rmag_0553 162 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 118602431 Common - glutamate 5-kinase Rmag_0413 194 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 118602882 Common - permease YjgP/YjgQ family protein Rmag_0913 79 COG0795 COG0795, Predicted permeases General function prediction only 118602848 Common - carbamoyl-phosphate synthase, small subunit Rmag_0877 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 118602776 Common - ABC transporter related Rmag_0799 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 118602338 Common - protein of unknown function DUF198 Rmag_0304 73 COG1469 COG1469, Uncharacterized conserved protein Function unknown 118602609 Common - Histidinol dehydrogenase Rmag_0602 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 118602542 Common - ATP phosphoribosyltransferase regulatory subunit Rmag_0532 104 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 118602815 Common - protein of unknown function DUF343 Rmag_0842 73 COG2835 COG2835, Uncharacterized conserved protein Function unknown 118602340 Common - DNA gyrase, A subunit Rmag_0306 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 118602118 Common - dephospho-CoA kinase Rmag_0061 200 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 118602648 Common - translation initiation factor IF-3 Rmag_0647 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 118602526 Common - OmpA/MotB domain protein Rmag_0516 142 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 118602387 Common - putative methyltransferase Rmag_0355 206 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 118602828 Common - Na+/Ca+ antiporter, CaCA family Rmag_0855 117 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 118602956 Common - ribosomal protein L28 Rmag_0994 164 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 118602506 Common - SUA5/yciO/yrdC, N-terminal domain Rmag_0495 128 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 118602393 Common dinG ATP-dependent DNA helicase DinG Rmag_0365 122 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 118602564 Common - acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase Rmag_0556 148 COG1043 LpxA, Acyl- acyl carrier protein 118602658 Nonpathogen - hypothetical protein Rmag_0660 1 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 118602226 Common - ribosomal protein S14 Rmag_0178 205 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 118602554 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Rmag_0546 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 118602788 Common - DNA-directed RNA polymerase, beta subunit Rmag_0811 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 118602865 Nonpathogen - hypothetical protein Rmag_0895 1 None None None 118602616 Common - holo-acyl-carrier-protein synthase Rmag_0610 100 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 118602763 Nonpathogen - hypothetical protein Rmag_0782 1 None None None 118602990 Common - hypothetical protein Rmag_1029 2 None None None 118602925 Common - ABC transporter related Rmag_0961 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 118602309 Common - phosphoserine phosphatase SerB Rmag_0271 152 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 118602232 Common - ribosomal protein L15 Rmag_0184 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 118602551 Common - lipoyl synthase Rmag_0543 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 118602356 Common - lysine 2,3-aminomutase YodO family protein Rmag_0322 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 118602639 Common - hypothetical protein Rmag_0638 2 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 118602584 Common - cysteine desulfurase IscS Rmag_0577 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 118602229 Common - ribosomal protein L18 Rmag_0181 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 118602382 Common - protein of unknown function DUF21 Rmag_0350 217 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 118602402 Nonpathogen - hypothetical protein Rmag_0376 4 None None None 118602082 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Rmag_0023 162 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 118602516 Common - Riboflavin synthase Rmag_0506 216 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 118602212 Common - ribosomal protein S10 Rmag_0164 244 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 118602735 Common - RDD domain containing protein Rmag_0752 12 COG1714 COG1714, Predicted membrane protein/domain Function unknown 118602670 Common - puttive membrane-associated protein with TPR-like domain Rmag_0672 45 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 118602180 Common - membrane bound O-acyl transferase, MBOAT family protein Rmag_0129 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 118602682 Common - protein serine/threonine phosphatases Rmag_0686 148 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 118602600 Common - cytidylate kinase Rmag_0593 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 118602279 Common - NADH-quinone oxidoreductase, E subunit Rmag_0241 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 118602594 Common - Ste24 endopeptidase Rmag_0587 99 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 118602852 Common - sulfite reductase, gamma subunit-related protein Rmag_0881 50 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 118603022 Common - iron-sulfur cluster assembly accessory protein Rmag_1062 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 118602478 Common - DNA polymerase III, subunits gamma and tau Rmag_0466 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 118602409 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Rmag_0384 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 118602699 Common - Bilirubin oxidase Rmag_0708 124 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 118602126 Common - hypothetical protein Rmag_0070 3 None None None 118602663 Common - ribosomal protein S18 Rmag_0665 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 118602827 Nonpathogen - hypothetical protein Rmag_0854 1 None None None 118602793 Common - NusG antitermination factor Rmag_0816 215 COG0250 NusG, Transcription antiterminator Transcription 118602524 Common - protein of unknown function DUF528 Rmag_0514 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 118602089 Common - protoheme IX farnesyltransferase Rmag_0030 165 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 118602451 Common - ribonuclease, Rne/Rng family Rmag_0436 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 118602115 Common - phosphoribosylamine--glycine ligase Rmag_0057 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 118602257 Common - putative signal-transduction protein with CBS domains Rmag_0214 57 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 118602167 Nonpathogen - hypothetical protein Rmag_0115 2 None None None 118602887 Common rpmA 50S ribosomal protein L27 Rmag_0918 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 118602441 Nonpathogen - hypothetical protein Rmag_0424 2 None None None 118603032 Common - ribosomal protein S2 Rmag_1072 226 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 118602155 Common - diaminopimelate decarboxylase Rmag_0103 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 118602895 Nonpathogen - hypothetical protein Rmag_0926 1 None None None 118602303 Common - phosphoribosylglycinamide formyltransferase Rmag_0265 223 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 118602482 Common - Serine-type D-Ala-D-Ala carboxypeptidase Rmag_0470 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 118602148 Common - adenylate kinases Rmag_0093 227 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 118602080 Common - peptidylprolyl isomerase, FKBP-type Rmag_0021 137 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 118602469 Common - magnesium transporter Rmag_0455 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 118602836 Nonpathogen - Nitrate reductase, gamma subunit Rmag_0864 21 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 118602103 Common - thioredoxin reductase Rmag_0044 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 118602739 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Rmag_0756 179 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 118602071 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Rmag_0011 90 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 118602783 Common - sulfur oxidation protein Rmag_0806 35 None None None 118602421 Common - methionine aminopeptidase, type I Rmag_0398 225 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 118602694 Common - Ribulose-bisphosphate carboxylase Rmag_0701 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 118602867 Common - hypothetical protein Rmag_0897 34 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 118602321 Common - response regulator receiver and ANTAR domain protein Rmag_0284 96 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 118602173 Common - tRNA(Ile)-lysidine synthetase Rmag_0122 201 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 118602724 Common glyQ glycyl-tRNA synthetase subunit alpha Rmag_0740 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 118602367 Nonpathogen - hypothetical protein Rmag_0334 1 None None None 118602928 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Rmag_0964 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 118602908 Common - DEAD/DEAH box helicase domain protein Rmag_0942 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 118602292 Nonpathogen - hypothetical protein Rmag_0254 1 None None None 118602360 Common - iojap-like protein Rmag_0326 194 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 118602854 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Rmag_0883 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 118602795 Common - elongation factor Tu Rmag_0818 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 118602833 Nonpathogen - hypothetical protein Rmag_0861 6 None None None 118602318 Common - DNA ligase (NAD(+)) Rmag_0280 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 118602176 Common - phosphate transporter Rmag_0125 148 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 118602313 Common - tRNA (guanine-N1)-methyltransferase Rmag_0275 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 118602685 Common - molybdopterin biosynthesis MoaE Rmag_0689 157 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 118602301 Common - excinuclease ABC, A subunit Rmag_0263 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 118602901 Common - Rhodanese domain protein Rmag_0932 97 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 118602710 Nonpathogen - hypothetical protein Rmag_0723 3 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 118602267 Common - SirA family protein Rmag_0225 115 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 118602434 Common - pantoate--beta-alanine ligase Rmag_0416 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 118602237 Common - ribosomal protein S4 Rmag_0189 224 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 118602770 Common - modification methylase, HemK family Rmag_0790 213 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 118602416 Common - phosphoribosylformylglycinamidine synthase Rmag_0392 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 118602632 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Rmag_0627 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 118602982 Common - transcription-repair coupling factor Rmag_1021 215 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 118602748 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Rmag_0765 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 118602766 Common - methionyl-tRNA formyltransferase Rmag_0785 227 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 118602876 Common - glycosyl transferase, family 25 Rmag_0907 26 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 118602191 Common - electron transport complex, RnfABCDGE type, C subunit Rmag_0141 129 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 118602534 Common nrdB ribonucleotide-diphosphate reductase subunit beta Rmag_0524 152 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 118602141 Nonpathogen - hypothetical protein Rmag_0086 2 None None None 118602498 Common - protein of unknown function DUF177 Rmag_0486 49 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 118602288 Common - proton-translocating NADH-quinone oxidoreductase, chain N Rmag_0250 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 118602120 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Rmag_0063 224 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 118602281 Common - NADH-quinone oxidoreductase, chain G Rmag_0243 189 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 118602230 Common - ribosomal protein S5 Rmag_0182 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 118602250 Common clpX ATP-dependent protease ATP-binding subunit Rmag_0206 226 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 118602433 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Rmag_0415 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 118602215 Common - Ribosomal protein L25/L23 Rmag_0167 174 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 118602260 Common - protein of unknown function DUF1538 Rmag_0217 23 None None None 118602186 Common - ATP-dependent metalloprotease FtsH Rmag_0136 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 118603007 Common - ATP synthase F1, alpha subunit Rmag_1047 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 118602350 Common - Rhodanese domain protein Rmag_0316 40 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 118602674 Common - glycosyl transferase, family 3 Rmag_0677 172 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 118602329 Common - ribosomal protein S15 Rmag_0293 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 118602456 Common - CinA domain protein Rmag_0441 188 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 118602458 Common - cell division protein FtsA Rmag_0443 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 118602532 Common - Ferrochelatase Rmag_0522 158 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 118602879 Common - stationary-phase survival protein SurE Rmag_0910 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 118602962 Nonpathogen - hypothetical protein Rmag_1000 1 None None None 118602248 Common - trigger factor Rmag_0204 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 118602414 Common - glutaredoxin-like protein Rmag_0389 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 118602974 Common - two component transcriptional regulator, LuxR family Rmag_1012 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 118602863 Common - cytidyltransferase-related domain Rmag_0893 59 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 118602859 Common - glycosyl transferase, family 2 Rmag_0889 172 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 118602689 Common - molybdenum cofactor biosynthesis protein A Rmag_0693 204 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 118602934 Common - 5-formyltetrahydrofolate cyclo-ligase Rmag_0971 164 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 118602953 Common - adenylosuccinate lyase Rmag_0991 229 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 118602613 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Rmag_0607 214 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 118602786 Common - anthranilate synthase component I Rmag_0809 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 118602927 Common - dihydrolipoamide dehydrogenase Rmag_0963 238 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 118602087 Common - imidazoleglycerol phosphate synthase, cyclase subunit Rmag_0028 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 118602331 Common - DNA primase Rmag_0295 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 118602544 Common - HflK protein Rmag_0534 168 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 118602607 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Rmag_0600 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 118602850 Common - thiamine biosynthesis protein ThiS Rmag_0879 33 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 118602547 Common - RNA methyltransferase, TrmH family, group 3 Rmag_0537 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 118602661 Common - glycosyl transferase, family 51 Rmag_0663 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 118602817 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Rmag_0844 158 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 118602111 Common - NusA antitermination factor Rmag_0053 220 COG0195 NusA, Transcription elongation factor Transcription 118602941 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Rmag_0978 125 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 118602950 Common - carbonic anhydrase Rmag_0988 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 118602528 Common - hypothetical protein Rmag_0518 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 118603028 Common - Aminoacyl-tRNA hydrolase Rmag_1068 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 118602624 Nonpathogen - hypothetical protein Rmag_0619 2 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 118602508 Common - SirA family protein Rmag_0497 65 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 118602521 Common - major facilitator superfamily MFS_1 Rmag_0511 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 118602264 Common - glutamate-1-semialdehyde-2,1-aminomutase Rmag_0222 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 118602345 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Rmag_0311 118 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 118602841 Common - sulfite reductase, dissimilatory-type beta subunit Rmag_0869 31 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 118602400 Common - asparagine synthase (glutamine-hydrolyzing) Rmag_0373 158 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 118602778 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Rmag_0801 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 118602116 Common - periplasmic or secreted lipoprotein-like Rmag_0058 55 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 118602495 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Rmag_0483 215 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 118602582 Common - iron-sulfur cluster assembly protein IscA Rmag_0575 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 118602201 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Rmag_0152 207 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 118602407 Common - radical SAM enzyme, Cfr family Rmag_0382 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 118602460 Common - acetolactate synthase, large subunit, biosynthetic type Rmag_0445 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 118602423 Common - LemA family protein Rmag_0400 130 COG1704 LemA, Uncharacterized conserved protein Function unknown 118602761 Common - peptidase M16 domain protein Rmag_0778 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 118602204 Common - Twin-arginine translocation pathway signal Rmag_0156 112 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 118602380 Common - prolyl-tRNA synthetase Rmag_0348 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602772 Common - cell shape determining protein, MreB/Mrl family Rmag_0794 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 118602210 Common - translation elongation factor G Rmag_0162 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 118602315 Common - ammonium transporter Rmag_0277 202 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 118602175 Common - protein of unknown function DUF47 Rmag_0124 37 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 118603020 Common - acetyl-CoA carboxylase, biotin carboxylase Rmag_1060 231 COG0439 AccC, Biotin carboxylase Lipid metabolism 118602668 Common - 5-nucleotidase Rmag_0670 30 None None None 118602378 Common - protein of unknown function UPF0061 Rmag_0346 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 118602904 Common - ribosomal protein S9 Rmag_0935 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 118602182 Common - tyrosyl-tRNA synthetase Rmag_0132 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602939 Common - protein of unknown function UPF0125 Rmag_0976 65 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 118602799 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Rmag_0824 134 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 118602680 Common - D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region Rmag_0684 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 118602224 Common - ribosomal protein L24 Rmag_0176 203 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 118602943 Common - ABC transporter related Rmag_0981 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 118602781 Nonpathogen - hypothetical protein Rmag_0804 1 None None None 118602475 Common - inosine-5'-monophosphate dehydrogenase Rmag_0462 238 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 118602756 Common - Cl- channel, voltage-gated family protein Rmag_0773 160 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 118602078 Nonpathogen - hypothetical protein Rmag_0019 9 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 118602419 Common - aspartyl-tRNA synthetase Rmag_0396 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602835 Nonpathogen - protein of unknown function DUF224, cysteine-rich region domain protein Rmag_0863 31 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 118602098 Common - cytochrome c oxidase, cbb3-type, subunit I Rmag_0039 143 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 118602227 Common - ribosomal protein S8 Rmag_0179 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 118602675 Common - Rieske (2Fe-2S) domain protein Rmag_0678 59 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 118602988 Common - ribosomal protein L31 Rmag_1027 205 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 118602906 Common - sulfatase Rmag_0937 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 118602113 Common - ribosome-binding factor A Rmag_0055 131 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 118602838 Common - DsrH family protein Rmag_0866 31 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 118602153 Common - 3-isopropylmalate dehydrogenase Rmag_0099 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 118602665 Common - replicative DNA helicase Rmag_0667 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 118602283 Common - NADH dehydrogenase subunit I Rmag_0245 189 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 118603013 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Rmag_1053 58 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 118602134 Common - DNA polymerase I Rmag_0078 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 118602937 Common - hypothetical protein Rmag_0974 65 COG2836 COG2836, Uncharacterized conserved protein Function unknown 118602596 Common - ribosome small subunit-dependent GTPase A Rmag_0589 163 COG1162 COG1162, Predicted GTPases General function prediction only 118602327 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Rmag_0290 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 118603005 Common - F0F1 ATP synthase subunit beta Rmag_1045 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 118602484 Common - protein of unknown function DUF498 Rmag_0472 20 COG3737 COG3737, Uncharacterized conserved protein Function unknown 118602447 Common - orotidine 5'-phosphate decarboxylase Rmag_0432 159 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 118602062 Common - DNA polymerase III, beta subunit Rmag_0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 118602101 Common - outer membrane lipoprotein carrier protein LolA Rmag_0042 8 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 118602399 Common - 3-isopropylmalate dehydratase, large subunit Rmag_0372 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 118602652 Common - FAD dependent oxidoreductase Rmag_0651 141 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 118602562 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Rmag_0554 171 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 118602501 Common - protein of unknown function DUF195 Rmag_0489 111 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 118602122 Common - Pyruvate kinase Rmag_0066 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 118602161 Common - ribose-phosphate pyrophosphokinase Rmag_0109 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 118603019 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Rmag_1059 194 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 118602143 Common - adenylylsulfate reductase Rmag_0088 61 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 118602913 Common - fructosamine kinase Rmag_0948 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 118602454 Common - putative undecaprenol kinase Rmag_0439 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 118602803 Nonpathogen - hypothetical protein Rmag_0829 1 None None None 118602091 Common - cytochrome oxidase assembly Rmag_0032 52 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 118602241 Common - methionine-R-sulfoxide reductase Rmag_0196 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 118602178 Common - DEAD/DEAH box helicase domain protein Rmag_0127 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 118602269 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Rmag_0228 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 118602960 Common - FxsA cytoplasmic membrane protein Rmag_0998 74 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 118602591 Common - branched-chain amino acid aminotransferase Rmag_0584 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 118602870 Common - putative 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase Rmag_0900 70 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 118602530 Common - NAD+ synthetase Rmag_0520 229 COG0171 NadE, NAD synthase Coenzyme metabolism 118602808 Common - 8-amino-7-oxononanoate synthase Rmag_0835 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 118602754 Common - hypothetical protein Rmag_0771 13 COG4637 COG4637, Predicted ATPase General function prediction only 118602659 Common - heme exporter protein CcmC Rmag_0661 128 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 118602493 Common - exodeoxyribonuclease VII, small subunit Rmag_0481 76 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 118602436 Nonpathogen - hypothetical protein Rmag_0418 2 None None None 118602262 Common - dTMP kinase Rmag_0220 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 118602903 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Rmag_0934 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 118602709 Nonpathogen - hypothetical protein Rmag_0722 4 None None None 118602683 Common - major facilitator superfamily MFS_1 Rmag_0687 143 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 118602715 Common - peptide chain release factor 1 Rmag_0731 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 118602235 Common rpsM 30S ribosomal protein S13 Rmag_0187 235 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 118602703 Common - cation diffusion facilitator family transporter Rmag_0714 205 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 118602980 Common - Dihydrofolate reductase Rmag_1019 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 118602764 Common - porphobilinogen deaminase Rmag_0783 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 118602573 Common - acyl carrier protein Rmag_0565 202 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 118602726 Common - MscS Mechanosensitive ion channel Rmag_0742 214 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 118602731 Common - hypothetical protein Rmag_0748 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 118602370 Common - tryptophanyl-tRNA synthetase Rmag_0338 223 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602425 Common - DNA-directed RNA polymerase, omega subunit Rmag_0405 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 118603026 Common - 2-polyprenylphenol 6-hydroxylase Rmag_1066 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 118602156 Common - protein of unknown function UPF0044 Rmag_0104 75 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 118602774 Common - rod shape-determining protein MreD Rmag_0796 42 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 118602406 Common - Nucleoside-diphosphate kinase Rmag_0381 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 118602304 Common - phosphoribosylformylglycinamidine cyclo-ligase Rmag_0266 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 118602170 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Rmag_0118 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 118602753 Common - threonine synthase Rmag_0770 147 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 118602915 Common - Imidazoleglycerol-phosphate dehydratase Rmag_0950 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 118602720 Common - heme exporter protein CcmA Rmag_0736 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 118602271 Common - oxidoreductase FAD/NAD(P)-binding domain protein Rmag_0233 90 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 118602203 Common - UDP-N-acetylmuramyl-tripeptide synthetases Rmag_0155 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 118602730 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Rmag_0747 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 118602669 Common - histidyl-tRNA synthetase Rmag_0671 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602385 Common - chaperone protein DnaK Rmag_0353 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 118602208 Common rpsL 30S ribosomal protein S12 Rmag_0160 237 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 118602819 Common - aspartate 1-decarboxylase Rmag_0846 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 118602592 Common - aspartate kinase Rmag_0585 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 118602349 Common - protein of unknown function DUF224, cysteine-rich region domain protein Rmag_0315 145 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 118602462 Common - ketol-acid reductoisomerase Rmag_0447 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 118602467 Common - acetylornithine and succinylornithine aminotransferases Rmag_0453 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 118602162 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Rmag_0110 194 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 118602253 Common - sun protein Rmag_0209 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 118602519 Common - histidine triad (HIT) protein Rmag_0509 218 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 118603016 Nonpathogen - hypothetical protein Rmag_1056 1 None None None 118602221 Common - ribosomal protein L29 Rmag_0173 72 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 118602474 Common - polynucleotide phosphorylase/polyadenylase Rmag_0461 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 118602741 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Rmag_0758 197 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 118602198 Common - tRNA synthetase, class II (D, K and N) Rmag_0148 203 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 118602325 Common - phosphoribosyl-ATP pyrophosphohydrolase Rmag_0288 179 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 118602351 Common - major facilitator superfamily MFS_1 Rmag_0317 98 None None None 118602445 Common - heat shock protein Hsp20 Rmag_0428 18 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 118602605 Common - excinuclease ABC, C subunit Rmag_0598 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 118602961 Common - FolC bifunctional protein Rmag_0999 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 118602844 Common rplS 50S ribosomal protein L19 Rmag_0872 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 118602811 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Rmag_0838 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 118602654 Common - short-chain dehydrogenase/reductase SDR Rmag_0654 230 COG0623 FabI, Enoyl- acyl-carrier-protein 118602546 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Rmag_0536 63 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 118602568 Common - RNA polymerase, sigma 32 subunit, RpoH Rmag_0560 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 118602643 Common - phenylalanyl-tRNA synthetase, beta subunit Rmag_0642 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 118602856 Common - UTP-glucose-1-phosphate uridylyltransferase Rmag_0885 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 118602085 Common - phosphatidate cytidylyltransferase Rmag_0026 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 118602922 Common - dihydroneopterin aldolase Rmag_0957 105 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 118602917 Common - protein of unknown function DUF34 Rmag_0952 102 COG0327 COG0327, Uncharacterized conserved protein Function unknown 118602611 Common - cytochrome c assembly protein Rmag_0605 106 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 118602802 Common - Dihydrodipicolinate reductase Rmag_0828 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 118602541 Common - Adenylosuccinate synthase Rmag_0531 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 118602698 Common - ABC transporter related Rmag_0707 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 118603035 Common - preprotein translocase, SecG subunit Rmag_1075 3 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 118602994 Nonpathogen - hypothetical protein Rmag_1033 1 None None None 118602759 Common - hypothetical protein Rmag_0776 7 None None None 118602822 Nonpathogen - sodium pump decarboxylases, gamma subunit Rmag_0849 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 118602999 Common - protein of unknown function DUF37 Rmag_1039 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 118602986 Common - tryptophan synthase, alpha subunit Rmag_1025 215 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 118602316 Common - dihydrodipicolinate synthase Rmag_0278 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 118602888 Common - ribosomal protein L21 Rmag_0919 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 118602376 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Rmag_0344 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 118602919 Common - Phosphomethylpyrimidine kinase type-1 Rmag_0954 222 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 118602183 Common - gamma-glutamyl phosphate reductase Rmag_0133 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 118602169 Common - phosphoglycolate phosphatase Rmag_0117 163 COG0546 Gph, Predicted phosphatases General function prediction only 118602412 Common - peptidase U32 Rmag_0387 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 118602438 Common - transcriptional regulator TraR/DksA family Rmag_0420 139 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 118602820 Common - sodium ion-translocating decarboxylase, beta subunit Rmag_0847 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 118602881 Common - ATP-dependent Clp protease adaptor protein ClpS Rmag_0912 116 COG2127 COG2127, Uncharacterized conserved protein Function unknown 118602744 Nonpathogen - hypothetical protein Rmag_0761 1 None None None 118602396 Common - GTP-binding protein TypA Rmag_0368 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 118602571 Common - DNA topoisomerase IV subunit B Rmag_0563 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 118602813 Common - Methenyltetrahydrofolate cyclohydrolase Rmag_0840 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 118602109 Common - glutathione synthetase Rmag_0051 126 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 118602578 Common - protein of unknown function DUF59 Rmag_0571 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 118602635 Common - Glycine hydroxymethyltransferase Rmag_0632 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 118602714 Common - Shikimate/quinate 5-dehydrogenase Rmag_0730 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 118602189 Common - electron transport complex, RnfABCDGE type, A subunit Rmag_0139 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 118602496 Common - fatty acid/phospholipid synthesis protein PlsX Rmag_0484 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 118602307 Nonpathogen - hypothetical protein Rmag_0269 2 None None None 118602234 Common - ribosomal protein L36 Rmag_0186 3 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 118602125 Common - methyltransferase GidB Rmag_0069 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 118602733 Common - exodeoxyribonuclease VII, large subunit Rmag_0750 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 118602946 Common - tRNA pseudouridine synthase A Rmag_0984 234 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 118602719 Common - peptidase S49 Rmag_0735 187 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 118602471 Common - positive regulator of sigma E, RseC/MucC Rmag_0457 13 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 118602145 Common - putative peptidyl-prolyl cis-trans isomerase Rmag_0090 78 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 118602094 Common - Cytochrome-c oxidase Rmag_0035 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 118602539 Common - dihydroxy-acid dehydratase Rmag_0529 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 118602806 Common - OsmC family protein Rmag_0833 83 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 118602967 Common - protein-export membrane protein SecF Rmag_1005 212 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 118602243 Common - hypothetical protein Rmag_0199 16 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 118602677 Nonpathogen - cold-shock DNA-binding domain protein Rmag_0680 1 None None None 118602065 Common - leucyl-tRNA synthetase Rmag_0005 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602873 Common - GDP-mannose 4,6-dehydratase Rmag_0903 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 118602417 Common - protein of unknown function DUF28 Rmag_0394 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 118602117 Common - Protein of unknown function UPF0011 Rmag_0059 208 COG0313 COG0313, Predicted methyltransferases General function prediction only 118602397 Common - acriflavin resistance protein Rmag_0369 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 118602599 Common rpsA 30S ribosomal protein S1 Rmag_0592 213 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 118602383 Common - Phosphopyruvate hydratase Rmag_0351 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 118602642 Common - histone family protein DNA-binding protein Rmag_0641 195 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 118602160 Common - RNA polymerase, sigma 70 subunit, RpoD Rmag_0108 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 118602649 Common - threonyl-tRNA synthetase Rmag_0648 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602344 Common - Peptidylprolyl isomerase Rmag_0310 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 118602790 Common - ribosomal protein L10 Rmag_0813 203 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 118602139 Common - OstA family protein Rmag_0084 46 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 118602728 Common - electron transport protein SCO1/SenC Rmag_0744 96 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 118602488 Common - thioredoxin Rmag_0476 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 118602552 Common - acriflavin resistance protein Rmag_0544 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 118602133 Common - ABC transporter related Rmag_0077 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 118602891 Common - ribonuclease II Rmag_0922 177 COG0557 VacB, Exoribonuclease R Transcription 118602213 Common - ribosomal protein L3 Rmag_0165 235 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 118602896 Common - putative endoribonuclease L-PSP Rmag_0927 176 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 118602486 Common - glutamyl-tRNA synthetase Rmag_0474 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 118602107 Common - ApbE family lipoprotein Rmag_0048 137 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 118602151 Common - cysteinyl-tRNA synthetase Rmag_0097 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602068 Common - Glutathione S-transferase, N-terminal domain Rmag_0008 66 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 118602357 Common - Redoxin domain protein Rmag_0323 131 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 118602972 Nonpathogen - hypothetical protein Rmag_1010 3 None None None 118602512 Common - cell cycle protein Rmag_0501 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 118602858 Common - sugar transferase Rmag_0887 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 118602295 Common - biotin biosynthesis protein BioC Rmag_0257 124 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 118602195 Common - succinyl-CoA synthetase, alpha subunit Rmag_0145 208 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 118602932 Common - helix-turn-helix, Fis-type Rmag_0968 66 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 118602277 Common - NADH (or F420H2) dehydrogenase, subunit C Rmag_0239 172 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 118602075 Common - dihydroorotase Rmag_0015 95 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 118602580 Common - Fe-S protein assembly chaperone HscA Rmag_0573 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 118602588 Common - PP-loop domain protein Rmag_0581 160 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 118602363 Common - pseudouridine synthase, RluA family Rmag_0329 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 118602667 Common - metallophosphoesterase Rmag_0669 76 COG1409 Icc, Predicted phosphohydrolases General function prediction only 118602481 Common - aminotransferase, class IV Rmag_0469 192 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 118602129 Common - 4-hydroxybenzoate polyprenyl transferase Rmag_0073 156 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 118602800 Common - hypothetical protein Rmag_0825 43 COG0778 NfnB, Nitroreductase Energy production and conversion 118602491 Common - GTP cyclohydrolase I Rmag_0479 98 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 118602559 Common - protein of unknown function DUF971 Rmag_0551 50 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 118602949 Common - Citrate transporter Rmag_0987 135 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 118602476 Common - SH3, type 3 domain protein Rmag_0463 33 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 118602273 Common - membrane protein-like Rmag_0235 55 COG3164 COG3164, Predicted membrane protein Function unknown 118602196 Common - succinyl-CoA synthetase, beta subunit Rmag_0146 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 118602968 Common - protein-export membrane protein SecD Rmag_1006 211 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 118602633 Common - phosphoserine aminotransferase Rmag_0628 109 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 118602342 Common - CMP/dCMP deaminase, zinc-binding Rmag_0308 57 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 118602743 Common - hypothetical protein Rmag_0760 10 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 118602586 Common - serine O-acetyltransferase Rmag_0579 196 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 118602576 Common - Oligopeptidase A Rmag_0568 124 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 118602102 Common - cell divisionFtsK/SpoIIIE Rmag_0043 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 118602311 Common - TPR repeat-containing protein Rmag_0273 62 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 118602205 Common - hypothetical protein Rmag_0157 33 None None None 118602900 Common - glutamine amidotransferase of anthranilate synthase Rmag_0931 234 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 118602798 Common - histidine triad (HIT) protein Rmag_0822 229 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 118602422 Common - peptidase M48, Ste24p Rmag_0399 180 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 118602722 Common - S-adenosylmethionine synthetase Rmag_0738 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 118602789 Common - ribosomal protein L7/L12 Rmag_0812 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 118602302 Common - hypothetical protein Rmag_0264 2 None None None 118602690 Nonpathogen - thiamineS protein Rmag_0694 2 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 118602073 Common - preprotein translocase, SecA subunit Rmag_0013 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 118602617 Common - pyridoxal phosphate biosynthetic protein PdxJ Rmag_0611 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 118602503 Common - inositol monophosphatase Rmag_0491 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 118602369 Common - putative transcriptional acitvator, Baf family Rmag_0337 105 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 118602737 Nonpathogen - Septum formation initiator Rmag_0754 1 None None None 118602692 Common - von Willebrand factor, type A Rmag_0699 43 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 118602959 Common - tRNA (guanine-N(7)-)-methyltransferase Rmag_0997 132 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 118602335 Nonpathogen - hypothetical protein Rmag_0299 1 None None None 118602389 Common - periplasmic sensor signal transduction histidine kinase Rmag_0361 215 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 118602362 Common - beta-lactamase domain protein Rmag_0328 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 118603030 Common - phosphoglyceromutase Rmag_1070 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 118602992 Common - tryptophan synthase subunit beta Rmag_1031 230 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 118602868 Common - glucose-1-phosphate adenylyltransferase related protein Rmag_0898 28 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 118602997 Common - ribosomal protein L34 Rmag_1037 92 None None None 118603024 Common - ubiquinone/menaquinone biosynthesis methyltransferases Rmag_1064 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 118602671 Common - small GTP-binding protein Rmag_0673 232 COG1160 COG1160, Predicted GTPases General function prediction only 118602602 Common - cytochrome C biogenesis protein Rmag_0595 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 118602603 Common - ABC transporter related Rmag_0596 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 118602621 Common - Thymidylate synthase Rmag_0616 137 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 118602442 Common - aminotransferase, class I and II Rmag_0425 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 118602846 Common - carbamoyl-phosphate synthase, large subunit Rmag_0875 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 118602792 Common - ribosomal protein L11 Rmag_0815 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 118602645 Common - hypothetical protein Rmag_0644 26 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 118602566 Common - hypothetical protein Rmag_0558 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 118602523 Common - (p)ppGpp synthetase I, SpoT/RelA Rmag_0513 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 118602548 Common - isocitrate lyase Rmag_0538 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 118602514 Common - riboflavin synthase subunit alpha Rmag_0504 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 118602404 Common smpB SsrA-binding protein Rmag_0379 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 118603015 Common - GrpE protein Rmag_1055 226 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 118602954 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Rmag_0992 214 COG1049 AcnB, Aconitase B Energy production and conversion 118602147 Common hppA membrane-bound proton-translocating pyrophosphatase Rmag_0092 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 118602105 Common - Holliday junction resolvase YqgF Rmag_0046 142 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 118602628 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Rmag_0623 235 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 118602473 Nonpathogen - hypothetical protein Rmag_0460 1 None None None 118602944 Common - biotin--acetyl-CoA-carboxylase ligase Rmag_0982 222 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 118602804 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Rmag_0831 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 118602861 Common - glycosyl transferase, family 2 Rmag_0891 159 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 118602286 Common - proton-translocating NADH-quinone oxidoreductase, chain L Rmag_0248 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 118602965 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Rmag_1003 80 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 118602096 Common - cytochrome c oxidase, subunit III Rmag_0037 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 118602537 Common - ribonuclease T Rmag_0527 60 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 118602410 Common - hypothetical protein Rmag_0385 39 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 118602127 Common - hydrolase, TatD family Rmag_0071 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 118602371 Common - Pseudouridine synthase, Rsu Rmag_0339 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 118602751 Common - NUDIX hydrolase Rmag_0768 115 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 118602245 Common - cytochrome c, class I Rmag_0201 25 COG2863 COG2863, Cytochrome c553 Energy production and conversion 118602453 Common - protein of unknown function DUF185 Rmag_0438 93 COG1565 COG1565, Uncharacterized conserved protein Function unknown 118602700 Common - hypothetical protein Rmag_0710 2 None None None 118602825 Nonpathogen - hypothetical protein Rmag_0852 1 None None None 118602874 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Rmag_0904 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 118602420 Common - protein of unknown function DUF502 Rmag_0397 83 COG2928 COG2928, Uncharacterized conserved protein Function unknown 118602712 Common - MotA/TolQ/ExbB proton channel Rmag_0725 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 118602374 Nonpathogen - hypothetical protein Rmag_0342 2 None None None 118602193 Common - electron transport complex, RnfABCDGE type, G subunit Rmag_0143 57 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 118602184 Common - DNA polymerase III, delta subunit Rmag_0134 69 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 118602266 Common - hypothetical protein Rmag_0224 41 COG2210 COG2210, Uncharacterized conserved protein Function unknown 118602239 Common - ribosomal protein L17 Rmag_0191 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 118602255 Common - Leucyl aminopeptidase Rmag_0211 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 118602465 Nonpathogen - hypothetical protein Rmag_0450 1 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 118602979 Common - Glutamate synthase (ferredoxin) Rmag_1018 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 118602746 Common - BolA family protein Rmag_0763 66 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 118602984 Common - hydroxymethylbutenyl pyrophosphate reductase Rmag_1023 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 118603002 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Rmag_1042 104 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 118602394 Common - Dimethylallyltranstransferase Rmag_0366 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 118602333 Nonpathogen - hypothetical protein Rmag_0297 1 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 118602814 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Rmag_0841 140 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 118602883 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Rmag_0914 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 118602970 Common - seryl-tRNA synthetase Rmag_1008 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 118602297 Common - methyltransferase, putative Rmag_0259 46 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 118602717 Common - ferric uptake regulator, Fur family Rmag_0733 198 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 118602688 Common - molybdenum cofactor biosynthesis protein C Rmag_0692 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 118602323 Common - twin-arginine translocation protein, TatB subunit Rmag_0286 24 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 118602275 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Rmag_0237 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 118602704 Common - thioredoxin Rmag_0716 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 118602165 Common - peptidase M24 Rmag_0113 206 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 118602211 Common - elongation factor Tu Rmag_0163 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 118602067 Common - dethiobiotin synthase Rmag_0007 143 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 118602083 Common - peptidase M23B Rmag_0024 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 118603009 Common - ATP synthase F0, B subunit Rmag_1049 117 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 118602137 Common - Thiamine-phosphate diphosphorylase Rmag_0082 193 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 118603034 Nonpathogen - hypothetical protein Rmag_1074 1 None None None 118602898 Common - Chorismate lyase Rmag_0929 44 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 118602893 Common - glycine cleavage system T protein Rmag_0924 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 118602359 Common - Glutathione S-transferase, N-terminal domain Rmag_0325 51 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 118602550 Common - lipoate-protein ligase B Rmag_0542 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 118602830 Common - cobyrinic acid a,c-diamide synthase Rmag_0858 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 118602130 Common - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase Rmag_0074 143 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 118602347 Common - FAD linked oxidase domain protein Rmag_0313 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion