Lactococcus lactis subsp. cremoris SK11, complete genome NC_008527 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 116512385 Common - hypothetical protein LACR_1683 4 None None None 116512453 Common - Transposase LACR_1751 25 None None None 116511411 Common - HPr kinase/phosphorylase LACR_0638 75 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 116510980 Common - cell surface protein LACR_0154 6 None None None 116513072 Common - Transcriptional regulator LACR_2420 11 COG1846 MarR, Transcriptional regulators Transcription 116511510 Common - Flavodoxin LACR_0743 4 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 116512575 Common smpB SsrA-binding protein LACR_1883 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 116510866 Nonpathogen - hypothetical protein LACR_0031 1 None None None 116512106 Common - Transposase LACR_1380 27 None None None 116511763 Common - hypothetical protein LACR_1019 38 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 116512019 Common - spermidine/putrescine ABC transporter permease protein LACR_1285 184 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116512189 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase LACR_1473 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116511756 Common - hypothetical protein LACR_1012 2 None None None 116513065 Common - FMN-binding protein LACR_2413 7 None None None 116512867 Common - Predicted transcriptional regulator LACR_2204 38 COG1695 COG1695, Predicted transcriptional regulators Transcription 116512811 Nonpathogen - hypothetical protein LACR_2131 1 None None None 116512932 Nonpathogen - hypothetical protein LACR_2270 2 None None None 116512009 Common - GTP cyclohydrolase I LACR_1275 209 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 116512971 Common - Rhodanese-related sulfurtransferase LACR_2310 11 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 116512745 Common - Cell division protein LACR_2060 45 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 116512161 Common - 2-dehydropantoate 2-reductase LACR_1445 117 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 116512039 Common - Alpha-acetolactate decarboxylase LACR_1307 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 116511222 Common ppnK inorganic polyphosphate/ATP-NAD kinase LACR_0409 224 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 116510890 Common - Transposase LACR_0057 27 None None None 116512790 Common - Phage terminase large subunit LACR_2109 13 COG1783 XtmB, Phage terminase large subunit General function prediction only 116512245 Common - 16S RNA G1207 methylase RsmC LACR_1532 110 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 116512096 Common - Mn-dependent transcriptional regulator LACR_1369 101 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 116512135 Common - Transposase LACR_1414 27 None None None 116511675 Common - 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase LACR_0921 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 116512412 Common pyrB aspartate carbamoyltransferase catalytic subunit LACR_1710 237 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 116512334 Common - Surface antigen LACR_1630 7 None None None 116512024 Common - Endoglucanase LACR_1290 10 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 116512438 Common - Phosphotransferase system, galactitol-specific IIB component LACR_1736 12 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 116512905 Common - galactose-1-phosphate uridylyltransferase LACR_2243 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 116511452 Common - Transposase LACR_0681 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512691 Common - Acetyltransferase, GNAT family LACR_2004 75 COG2153 ElaA, Predicted acyltransferase General function prediction only 116512120 Common scpA segregation and condensation protein A LACR_1398 145 COG1354 COG1354, Uncharacterized conserved protein Function unknown 116511642 Common - L-serine deaminase LACR_0887 145 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 116511272 Common - hypothetical protein LACR_0463 60 COG1434 COG1434, Uncharacterized conserved protein Function unknown 116511023 Common - Uncharacterized membrane-bound protein conserved in bacteria LACR_0199 7 COG4858 COG4858, Uncharacterized membrane-bound protein conserved in bacteria Function unknown 116511461 Common - Mg2+ and Co2+ transporter LACR_0690 35 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 116512450 Common - permease of the major facilitator superfamily LACR_1748 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511312 Nonpathogen - hypothetical protein LACR_0507 1 None None None 116511101 Common - hypothetical protein LACR_0284 7 None None None 116511426 Common - Short-chain dehydrogenase of various substrate specificities LACR_0655 191 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116512689 Common - Predicted permease LACR_2001 194 COG0628 PerM, Predicted permease General function prediction only 116511172 Common - Predicted membrane protein LACR_0359 13 COG3859 COG3859, Predicted membrane protein Function unknown 116511612 Common - Transposase LACR_0855 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512426 Common - Acetyltransferase, including N-acetylase of ribosomal protein LACR_1724 105 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116512406 Common - hypothetical protein LACR_1704 6 None None None 116512870 Common - adenylosuccinate synthetase LACR_2207 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 116512516 Common holA DNA polymerase III subunit delta LACR_1819 37 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 116513079 Nonpathogen - hypothetical protein LACR_2430 1 None None None 116511234 Common - Transcriptional regulator LACR_0422 151 COG0583 LysR, Transcriptional regulator Transcription 116510991 Common - 4-amino-4-deoxy-L-arabinose transferase related glycosyltransferase of PMT family LACR_0166 2 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116511988 Common - Predicted sugar phosphatase of the HAD superfamily LACR_1254 101 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 116512679 Common - Superfamily II DNA helicase LACR_1991 223 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 116512054 Common - hypothetical protein LACR_1324 109 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 116512530 Nonpathogen - hypothetical protein LACR_1834 1 None None None 116511284 Common - hypothetical protein LACR_0477 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 116511588 Common - acetyl-CoA carboxylase subunit beta LACR_0829 216 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 116510998 Common - Na+-driven multidrug efflux pump LACR_0173 173 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 116512805 Nonpathogen - hypothetical protein LACR_2125 1 None None None 116511860 Nonpathogen - hypothetical protein LACR_1119 1 None None None 116512474 Nonpathogen - hypothetical protein LACR_1774 1 None None None 116511619 Common - dsRNA-specific ribonuclease LACR_0862 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 116511073 Common - Predicted hydrolase (HAD superfamily) LACR_0249 61 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116511205 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component LACR_0392 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116512271 Common - Anthranilate/para-aminobenzoate synthase component II LACR_1559 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 116512560 Common - hypothetical protein LACR_1868 50 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116511439 Common eno phosphopyruvate hydratase LACR_0668 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 116512942 Common - Diadenosine tetraphosphate (Ap4A) hydrolase related HIT family hydrolase LACR_2280 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 116511094 Common - anaerobic ribonucleoside triphosphate reductase LACR_0277 104 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 116512030 Common - Putative intracellular protease/amidase LACR_1296 77 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 116512737 Nonpathogen - hypothetical protein LACR_2051 1 None None None 116513215 Nonpathogen - hypothetical protein LACR_2591 1 None None None 116512303 Common - xylose isomerase LACR_1596 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 116512511 Common - proline dipeptidase LACR_1813 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 116513039 Common - Ribosomal protein S8 LACR_2387 249 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 116511391 Common glyA serine hydroxymethyltransferase LACR_0617 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 116511060 Common - Predicted nucleotidyltransferase LACR_0236 25 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 116512644 Common - Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II LACR_1955 143 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116512813 Nonpathogen - hypothetical protein LACR_2133 1 None None None 116511161 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase LACR_0348 214 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 116511146 Nonpathogen - hypothetical protein LACR_0332 1 None None None 116510853 Common - peptidyl-tRNA hydrolase LACR_0010 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 116511019 Common - methionine sulfoxide reductase B LACR_0195 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 116511363 Common - 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase LACR_0586 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 116511966 Nonpathogen - hypothetical protein LACR_1230 1 None None None 116513203 Nonpathogen - DNA segregation ATPase FtsK/SpoIIIE related protein LACR_2579 1 None None None 116512442 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase LACR_1740 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 116511126 Common - hypothetical protein LACR_0312 2 None None None 116512292 Common - Transcriptional regulator and fructokinase LACR_1584 96 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116511398 Common - hypothetical protein, contains double-stranded beta-helix domain LACR_0624 54 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116511204 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component LACR_0391 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116512717 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component LACR_2030 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116512398 Common murG N-acetylglucosaminyl transferase LACR_1696 210 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 116512650 Common - Predicted membrane protein LACR_1962 22 COG1511 COG1511, Predicted membrane protein Function unknown 116511977 Common murQ N-acetylmuramic acid-6-phosphate etherase LACR_1241 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 116512523 Common - Predicted dehydrogenase related protein LACR_1826 114 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116511690 Common - Protein required for the initiation of cell division LACR_0936 2 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 116511581 Common acpP acyl carrier protein LACR_0822 164 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116511378 Common - hypothetical protein LACR_0604 2 None None None 116512612 Common - Uncharacterized membrane-associated protein LACR_1922 163 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 116511813 Common - DNA topoisomerase IV subunit A LACR_1070 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 116512047 Common - isopropylmalate isomerase large subunit LACR_1317 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 116511833 Common - Signal transduction histidine kinase LACR_1092 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116512000 Common - Xanthine/uracil permease LACR_1266 129 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 116511305 Nonpathogen - hypothetical protein LACR_0500 1 None None None 116511703 Common - Glycosyltransferase LACR_0949 213 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116512482 Nonpathogen - hypothetical protein LACR_1782 1 None None None 116511857 Nonpathogen - hypothetical protein LACR_1116 1 None None None 116511696 Common - malolactic fermentation system transcription activator LACR_0942 166 COG0583 LysR, Transcriptional regulator Transcription 116510905 Nonpathogen - hypothetical protein LACR_0072 1 None None None 116511338 Common - Muramidase (flagellum-specific) LACR_0538 96 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 116512965 Common - Transposase LACR_2303 26 None None None 116510959 Common - Ribosomal protein L34 LACR_0132 13 None None None 116512436 Common - transketolase LACR_1734 219 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 116511773 Common - Predicted oxidoreductase; Myosin-crossreactive antigen ortholog LACR_1029 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 116512085 Common - Transposase LACR_1358 34 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512726 Nonpathogen - hypothetical protein LACR_2040 1 None None None 116511771 Common - Molecular chaperone LACR_1027 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 116512563 Common - Transposase LACR_1871 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511656 Common - Nicotinamide mononucleotide transporter LACR_0901 35 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 116511324 Common - hypothetical protein LACR_0521 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 116511045 Common - hypothetical protein LACR_0221 2 None None None 116511437 Common - ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones LACR_0666 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 116510977 Common - cell surface protein LACR_0151 8 None None None 116512251 Common - Predicted phosphoadenosine phosphosulfate sulfotransferase LACR_1538 17 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 116510846 Common - ATP-dependent nuclease, subunit B LACR_0003 27 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 116513103 Nonpathogen - hypothetical protein LACR_2458 1 None None None 116511732 Common - P-Ser-HPr phosphatase LACR_0983 28 COG0546 Gph, Predicted phosphatases General function prediction only 116510967 Common - Predicted integral membrane protein LACR_0140 23 COG3548 COG3548, Predicted integral membrane protein Function unknown 116510912 Common - Uncharacterized membrane-anchored protein conserved in bacteria LACR_0079 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 116512465 Common - hypothetical protein LACR_1765 5 None None None 116510934 Common - Phosphotransferase system, HPr-related protein LACR_0103 103 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 116512539 Common - Transcriptional regulator LACR_1846 128 COG1609 PurR, Transcriptional regulators Transcription 116512417 Common - Co/Zn/Cd efflux system component LACR_1715 194 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 116512226 Common - Lactoylglutathione lyase related lyase LACR_1512 38 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116511566 Nonpathogen - hypothetical protein LACR_0804 1 None None None 116512623 Common - F0F1 ATP synthase subunit beta LACR_1933 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 116512428 Common - Subtilisin-like serine protease LACR_1726 20 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 116511946 Common - UDP-N-acetylmuramyl tripeptide synthase LACR_1208 90 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 116513053 Common rplD 50S ribosomal protein L4 LACR_2401 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 116511751 Common - Formyltetrahydrofolate synthetase LACR_1007 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 116511555 Common - Predicted choline kinase LACR_0792 9 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 116511912 Common - Predicted EndoIII-related endonuclease LACR_1172 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 116512659 Common - Uncharacterized membrane-associated protein LACR_1971 4 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 116511522 Common - Metal-dependent hydrolase of the beta-lactamase superfamily III LACR_0757 101 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 116511114 Common rpsD 30S ribosomal protein S4 LACR_0300 246 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 116511919 Nonpathogen - hypothetical protein LACR_1179 5 COG3371 COG3371, Predicted membrane protein Function unknown 116511244 Nonpathogen - hypothetical protein LACR_0434 1 None None None 116513034 Common - Ribosomal protein L15 LACR_2382 215 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 116512835 Common - primosome assembly protein PriA LACR_2156 215 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 116512958 Common - Adenine-specific DNA methylase LACR_2296 11 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 116511870 Nonpathogen - hypothetical protein LACR_1129 1 None None None 116511141 Common - Metal-dependent protease related protein, putative molecular chaperone LACR_0327 182 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 116511534 Common - Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II LACR_0770 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116512289 Common - ABC-type sugar transport system, periplasmic component LACR_1580 20 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116511561 Common - Uncharacterized low-complexity protein LACR_0798 36 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 116511802 Common - Cell division protein LACR_1059 120 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 116512669 Common rpoB DNA-directed RNA polymerase subunit beta LACR_1981 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 116513030 Common rpmJ 50S ribosomal protein L36 LACR_2378 138 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 116512666 Common - ABC-type amino acid transport system, permease component LACR_1978 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116513012 Nonpathogen - hypothetical protein LACR_2357 1 None None None 116511028 Common - dTDP-D-glucose 4,6-dehydratase LACR_0204 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 116513083 Common - CDP-diglyceride synthetase LACR_2434 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 116512543 Common - Galactoside O-acetyltransferase LACR_1850 194 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116511331 Common - hypothetical protein LACR_0531 3 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 116512374 Common - Transposase LACR_1671 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511747 Common - hypothetical protein LACR_1002 13 None None None 116513019 Common - Histidinol phosphatase related phosphatase LACR_2364 121 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 116511038 Common - hypothetical protein LACR_0214 2 COG2456 COG2456, Uncharacterized conserved protein Function unknown 116511454 Common - hypothetical protein LACR_0683 5 None None None 116511116 Common - Predicted transcriptional regulator LACR_0302 9 COG3655 COG3655, Predicted transcriptional regulator Transcription 116511557 Common - hypothetical protein LACR_0794 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 116512091 Common - Transposase LACR_1364 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511548 Common - Predicted esterase of the alpha-beta hydrolase superfamily LACR_0785 3 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 116511891 Nonpathogen - hypothetical protein LACR_1151 1 None None None 116511954 Common - Membrane-associated lipoprotein for thiamine biosynthesis LACR_1217 127 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 116512695 Common - Uracil-DNA glycosylase LACR_2008 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 116511787 Nonpathogen - DNA-binding ferritin-like protein (oxidative damage protectant) LACR_1044 5 None None None 116511697 Common - Transposase LACR_0943 26 None None None 116511030 Common - Glycosyltransferase LACR_0206 27 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116513002 Common gltX glutamyl-tRNA synthetase LACR_2346 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 116512124 Common - Xanthosine triphosphate pyrophosphatase LACR_1402 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 116512284 Common - Na+-driven multidrug efflux pump LACR_1575 147 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 116511393 Common - phosphoserine aminotransferase LACR_0619 114 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 116511816 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase LACR_1074 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 116512757 Common - Predicted HD superfamily hydrolase for NAD metabolism LACR_2074 30 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 116511944 Common - ABC-type antimicrobial peptide transport system, permease component LACR_1206 69 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116511794 Common - ABC-type multidrug transport system, ATPase component LACR_1051 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116510921 Nonpathogen - hypothetical protein LACR_0088 5 None None None 116511543 Common - L-asparaginase LACR_0779 143 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 116512876 Nonpathogen - hypothetical protein LACR_2214 1 None None None 116511214 Common - Gamma-aminobutyrate permease related permease LACR_0401 92 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 116512376 Nonpathogen - hypothetical protein LACR_1673 1 None None None 116511574 Common - Predicted nucleic-acid-binding protein implicated in transcription termination LACR_0815 30 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 116512243 Nonpathogen - hypothetical protein LACR_1530 1 None None None 116511350 Common - Transposase LACR_0551 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513049 Common rplV 50S ribosomal protein L22 LACR_2397 231 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 116511515 Common - Predicted nucleic-acid-binding protein containing a Zn-ribbon domain LACR_0749 13 COG3478 COG3478, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 116511083 Common - ABC-type multidrug transport system, ATPase and permease component LACR_0265 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116513013 Common - Integral membrane protein (PIN domain superfamily) LACR_2358 45 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 116513073 Nonpathogen - hypothetical protein LACR_2421 1 None None None 116511185 Common - ABC-type Fe3+-siderophore transport system, permease component LACR_0372 133 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 116512901 Common - Gamma-carboxymuconolactone decarboxylase-like protein LACR_2239 88 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 116511092 Common - hypothetical protein LACR_0274 2 None None None 116512489 Nonpathogen - hypothetical protein LACR_1789 1 None None None 116511502 Nonpathogen - hypothetical protein LACR_0735 1 None None None 116511665 Common - Arsenate reductase related protein, glutaredoxin family LACR_0911 39 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116513007 Nonpathogen - hypothetical protein LACR_2351 1 None None None 116513129 Common - tRNA (uracil-5-)-methyltransferase related enzyme LACR_2487 192 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 116511634 Common - Alpha/beta superfamily hydrolase LACR_0879 146 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116511671 Nonpathogen - hypothetical protein LACR_0917 1 None None None 116512360 Common - hypothetical protein LACR_1657 3 COG4835 COG4835, Uncharacterized protein conserved in bacteria Function unknown 116511365 Common - OxaA-like protein precursor LACR_0588 175 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 116512297 Nonpathogen - Peptidase E LACR_1589 2 COG3340 PepE, Peptidase E Amino acid transport and metabolism 116512787 Nonpathogen - hypothetical protein LACR_2106 1 None None None 116512589 Common - Integral membrane protein, interacts with FtsH LACR_1899 142 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 116511965 Common - cell surface protein LACR_1229 8 None None None 116511178 Common - ABC-type metal ion transport system, ATPase component LACR_0365 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 116511824 Common - hypothetical protein LACR_1083 29 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 116512625 Common - F0F1 ATP synthase subunit alpha LACR_1935 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 116510888 Nonpathogen - hypothetical protein LACR_0054 1 None None None 116512345 Nonpathogen - hypothetical protein LACR_1642 4 None None None 116511701 Common - Acetyltransferase, GNAT family LACR_0947 24 COG0456 RimI, Acetyltransferases General function prediction only 116511986 Common - Deoxycytidylate deaminase LACR_1252 91 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 116513095 Common - Predicted hydrolase of the HAD superfamily LACR_2446 95 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116510874 Common - Transposase LACR_0039 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512349 Common - Predicted dehydrogenase related protein LACR_1646 159 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116511017 Common - Fe2+ transport system protein B LACR_0193 153 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 116512205 Common - hypothetical protein LACR_1490 6 None None None 116512087 Common - Transposase LACR_1360 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511840 Common - Transcriptional regulator, xre family LACR_1099 15 COG1396 HipB, Predicted transcriptional regulators Transcription 116512236 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_1523 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116512894 Common - hypothetical protein LACR_2232 3 None None None 116512138 Common - Integrase LACR_1417 45 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116513197 Common - hypothetical protein LACR_2573 23 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 116512388 Common - hypothetical protein LACR_1686 2 None None None 116512968 Nonpathogen - hypothetical protein LACR_2307 1 None None None 116512105 Nonpathogen - hypothetical protein LACR_1379 1 None None None 116512619 Common - Transposase LACR_1929 31 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511933 Common - hypothetical protein LACR_1195 7 None None None 116512199 Common - 16S rRNA uridine-516 pseudouridylate synthase related pseudouridylate synthase LACR_1484 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 116512945 Common rplA 50S ribosomal protein L1 LACR_2283 241 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 116511052 Common - GTPase LACR_0228 217 COG2262 HflX, GTPases General function prediction only 116512887 Common - hypothetical protein LACR_2225 78 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116511598 Common - Acetyltransferase, including N-acetylase of ribosomal protein LACR_0840 116 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116512342 Common - Pentose-5-phosphate-3-epimerase LACR_1639 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 116511294 Common - Predicted ATPase or kinase LACR_0487 183 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 116512502 Common - ribose operon repressor LACR_1803 125 COG1609 PurR, Transcriptional regulators Transcription 116511285 Common - hypothetical protein LACR_0478 16 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 116511418 Nonpathogen - hypothetical protein LACR_0645 1 None None None 116511277 Common - cellobiose-specific PTS system IIC component LACR_0468 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 116511627 Common - Predicted hydrolase of the HAD superfamily LACR_0870 126 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116512881 Nonpathogen - hypothetical protein LACR_2219 1 None None None 116511688 Common - Predicted membrane protein LACR_0934 4 COG3152 COG3152, Predicted membrane protein Function unknown 116513111 Common - DNA-directed RNA polymerase specialized sigma subunit, sigma24-like protein LACR_2468 8 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116511377 Common - hypothetical protein LACR_0602 3 None None None 116510883 Common - acetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase LACR_0049 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 116512143 Nonpathogen - hypothetical protein LACR_1422 1 None None None 116512934 Nonpathogen - hypothetical protein LACR_2272 1 None None None 116511845 Nonpathogen - hypothetical protein LACR_1104 1 None None None 116512056 Common - Phosphoribosyl-ATP pyrophosphohydrolase LACR_1326 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 116512166 Common - Fibronectin-binding protein LACR_1450 84 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 116513218 Nonpathogen - Prenylated rab acceptor 1 related protein LACR_2594 1 COG5130 YIP3, Prenylated rab acceptor 1 and related proteins Intracellular trafficking and secretion / Signal transduction mechanisms 116512862 Common - ribosome-associated GTPase LACR_2198 163 COG1162 COG1162, Predicted GTPases General function prediction only 116512215 Common - Cation transport ATPase LACR_1501 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116513189 Common - Glyceraldehyde-3-phosphate dehydrogenase LACR_2555 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 116512803 Nonpathogen - hypothetical protein LACR_2122 1 None None None 116512596 Common - Shikimate kinase LACR_1906 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 116512820 Nonpathogen - hypothetical protein LACR_2140 1 None None None 116512327 Common - hypothetical protein, contains double-stranded beta-helix domain LACR_1623 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116512923 Nonpathogen - hypothetical protein LACR_2261 1 None None None 116512996 Common - hypothetical protein LACR_2338 8 COG5646 COG5646, Uncharacterized conserved protein Function unknown 116511761 Common - Metal-dependent hydrolase LACR_1017 11 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 116511981 Common - hypothetical protein LACR_1246 6 None None None 116511071 Common - Predicted hydrolase of the HAD superfamily LACR_0247 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116511326 Common - Beta-glucosidase-related glycosidase LACR_0523 176 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 116512632 Common - Transposase LACR_1943 26 None None None 116513223 Common - D-alanyl-D-alanine carboxypeptidase LACR_2600 130 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116512718 Common - Ribosomal protein L20 LACR_2031 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 116511995 Nonpathogen - hypothetical protein LACR_1261 1 None None None 116512265 Common - Predicted lactoylglutathione lyase LACR_1553 54 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 116511935 Common - Glycyl-tRNA synthetase, beta subunit LACR_1197 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 116511152 Nonpathogen - hypothetical protein LACR_0339 1 None None None 116512775 Common - SLT domain protein LACR_2094 19 COG3953 COG3953, SLT domain proteins General function prediction only 116511869 Nonpathogen - hypothetical protein LACR_1128 1 None None None 116512827 Nonpathogen - hypothetical protein LACR_2147 1 COG5547 COG5547, Small integral membrane protein Function unknown 116512762 Common - N-acetylglucosamine-1-phosphate uridyltransferase, nucleotidyltransferase and I-patch acetyltransferase domains LACR_2079 236 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 116513147 Nonpathogen - hypothetical protein LACR_2511 1 None None None 116513136 Common - Predicted phosphohydrolase LACR_2500 96 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 116511879 Common - hypothetical protein LACR_1139 5 None None None 116511111 Common - Predicted xylanase/chitin deacetylase LACR_0295 112 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116511137 Common - Predicted transcriptional regulator LACR_0323 89 COG0789 SoxR, Predicted transcriptional regulators Transcription 116511270 Common - Acyl carrier protein phosphodiesterase LACR_0460 65 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 116512877 Nonpathogen - hypothetical protein LACR_2215 1 None None None 116511196 Common - Peroxiredoxin LACR_0383 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116512684 Common - peptidase T LACR_1996 58 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 116513156 Common - Predicted membrane protein LACR_2520 7 COG4550 COG4550, Predicted membrane protein Function unknown 116512223 Common - Universal stress protein UspA related nucleotide-binding protein LACR_1509 128 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116512115 Common - ABC-type multidrug transport system, ATPase and permease component LACR_1391 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116512311 Common - Predicted hydrolase (HAD superfamily) LACR_1604 68 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116512194 Common - ABC-type sugar transport system, periplasmic component LACR_1478 30 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116513198 Common - Adenine specific DNA methylase Mod LACR_2574 93 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 116512735 Common - ribose-phosphate pyrophosphokinase LACR_2049 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 116511524 Common - Cytosine/adenosine deaminase LACR_0760 211 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 116511424 Common - Transcriptional regulator, xre family LACR_0652 9 None None None 116511236 Common - Tellurite resistance protein related permease LACR_0424 36 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 116511174 Common - ABC-type metal ion transport system, periplasmic component/surface antigen LACR_0361 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 116512052 Nonpathogen - hypothetical protein LACR_1322 1 None None None 116511262 Common - ABC-type multidrug transport system, ATPase component LACR_0452 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116512799 Common - dUTPase LACR_2118 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 116512518 Common - DNA segregation ATPase FtsK/SpoIIIE related protein LACR_1821 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 116512480 Nonpathogen - hypothetical protein LACR_1780 1 None None None 116511905 Nonpathogen - hypothetical protein LACR_1165 1 None None None 116512459 Nonpathogen - hypothetical protein LACR_1758 1 None None None 116511499 Common - Predicted metal-dependent membrane protease LACR_0732 9 None None None 116513026 Common - Ribosomal protein L17 LACR_2374 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 116512677 Common - Transposase LACR_1989 26 None None None 116513134 Common - Transcriptional regulator LACR_2498 89 COG1737 RpiR, Transcriptional regulators Transcription 116511078 Common - ABC-type multidrug transport system, permease component LACR_0258 109 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 116511637 Common - Transposase LACR_0882 137 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512032 Nonpathogen - hypothetical protein LACR_1300 1 None None None 116511372 Common - Transposase LACR_0597 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512911 Common - NMN adenylytransferase and ribosylnicotinamide kinase, NadR ortholog LACR_2249 25 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 116511617 Common - Ornithine carbamoyltransferase LACR_0860 236 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 116510992 Common - aminotransferase AlaT LACR_0167 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116512029 Common - Predicted transcriptional regulator LACR_1295 50 COG0640 ArsR, Predicted transcriptional regulators Transcription 116511862 Nonpathogen - hypothetical protein LACR_1121 1 None None None 116511768 Nonpathogen - hypothetical protein LACR_1024 1 None None None 116512383 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase LACR_1680 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 116512045 Common - Transposase LACR_1315 27 None None None 116512476 Common - Phage Mu protein F like protein LACR_1776 8 None None None 116511229 Common - Transposase LACR_0416 138 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512815 Common - Uncharacterized phage-encoded protein LACR_2135 40 COG3617 COG3617, Prophage antirepressor Transcription 116511669 Nonpathogen - hypothetical protein LACR_0915 2 COG5253 MSS4, Phosphatidylinositol-4-phosphate 5-kinase Signal transduction mechanisms 116512554 Nonpathogen - LysM domain LACR_1861 1 None None None 116512528 Nonpathogen - hypothetical protein LACR_1832 1 None None None 116512043 Common - dihydroxy-acid dehydratase LACR_1312 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 116511610 Common - Transposase LACR_0853 24 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511319 Common - Deoxynucleoside kinase LACR_0515 39 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 116512802 Nonpathogen - hypothetical protein LACR_2121 1 None None None 116511644 Common - Predicted transcriptional regulator LACR_0889 36 COG3682 COG3682, Predicted transcriptional regulator Transcription 116511163 Common - Transposase LACR_0350 27 None None None 116511941 Common - Acetyltransferase, GNAT family LACR_1203 50 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116513032 Common - Adenylate kinase LACR_2380 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 116512336 Common - Response regulator containing AraC-type DNA-binding domain LACR_1633 118 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116510868 Common - alpha/beta hydrolase superfamily protein LACR_0033 9 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 116511248 Common - single-strand DNA-binding protein LACR_0438 188 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 116511512 Common - Predicted integral membrane protein LACR_0746 21 COG3548 COG3548, Predicted integral membrane protein Function unknown 116512187 Common - permease of the major facilitator superfamily LACR_1471 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512316 Common purN phosphoribosylglycinamide formyltransferase LACR_1610 217 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 116512869 Common - hypothetical protein LACR_2206 28 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 116512614 Common - ABC-type polar amino acid transport system, ATPase component LACR_1924 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116513191 Common - Cation transport ATPase LACR_2557 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116513070 Common - ABC-type Mn/Zn transport system, ATPase component LACR_2418 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 116511971 Nonpathogen - hypothetical protein LACR_1235 2 None None None 116512101 Common - D-alanine--D-alanyl carrier protein ligase LACR_1374 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 116512247 Nonpathogen - phosphate-starvation-inducible protein PsiE LACR_1534 1 COG3223 COG3223, Predicted membrane protein Function unknown 116510970 Common - Short-chain dehydrogenase (D-alanine transfer protein) LACR_0143 161 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 116512464 Nonpathogen - hypothetical protein LACR_1764 2 None None None 116511754 Common - ABC-type amino acid transport system, permease component LACR_1010 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116511310 Nonpathogen - hypothetical protein LACR_0505 1 None None None 116510950 Common - Transposase LACR_0121 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512569 Common - ABC-type phosphate transport system, ATPase component LACR_1877 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 116511035 Common - Glycosyltransferase LACR_0211 178 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116511881 Common - hypothetical protein LACR_1141 6 None None None 116511673 Common - Transposase LACR_0919 27 None None None 116511463 Common coaE dephospho-CoA kinase LACR_0692 204 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 116512570 Common - ABC-type phosphate transport system, ATPase component LACR_1878 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 116511923 Common - Mn2+ or Fe2+ transporter of the NRAMP family LACR_1183 91 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 116510850 Common - translation-associated GTPase LACR_0007 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 116512133 Common - Glutamate gamma-aminobutyrate antiporter LACR_1412 132 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 116512098 Common - D-alanyl transfer protein LACR_1371 13 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 116511694 Common - ABC-type antimicrobial peptide transport system, permease component LACR_0940 12 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116512573 Common - ABC-type phosphate transport system, periplasmic component LACR_1881 165 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 116512280 Common - Short-chain alcohol dehydrogenase of unknown specificity LACR_1571 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116512424 Common - Predicted dinucleotide-binding enzyme LACR_1722 36 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 116512963 Nonpathogen - hypothetical protein LACR_2301 1 None None None 116512328 Common - hypothetical protein LACR_1624 6 COG1359 COG1359, Uncharacterized conserved protein Function unknown 116512295 Common - Predicted integral membrane protein LACR_1587 4 COG5578 COG5578, Predicted integral membrane protein Function unknown 116512621 Nonpathogen - hypothetical protein LACR_1931 1 None None None 116512372 Common - Transposase LACR_1669 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511401 Common - Inorganic pyrophosphatase LACR_0627 8 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 116511249 Common groES co-chaperonin GroES LACR_0439 210 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 116511333 Nonpathogen - hypothetical protein LACR_0533 1 None None None 116512200 Common glpK glycerol kinase LACR_1485 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 116512872 Common hslO Hsp33-like chaperonin LACR_2209 135 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 116511568 Common - Sortase (surface protein transpeptidase) LACR_0807 18 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 116511737 Common - Transposase LACR_0990 26 None None None 116511386 Nonpathogen - hypothetical protein LACR_0612 1 None None None 116511076 Common - Glycerol uptake facilitator related permease (Major Intrinsic Protein Family) LACR_0255 83 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 116511734 Nonpathogen - hypothetical protein LACR_0985 1 None None None 116512956 Common - Acetate kinase LACR_2294 161 COG0282 ackA, Acetate kinase Energy production and conversion 116512891 Nonpathogen - hypothetical protein LACR_2229 2 None None None 116511475 Common - Transposase LACR_0707 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510911 Common - Cation transport ATPase LACR_0078 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116511120 Nonpathogen - hypothetical protein LACR_0306 1 None None None 116512628 Common - F0F1 ATP synthase subunit A LACR_1938 198 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 116511303 Nonpathogen - hypothetical protein LACR_0498 1 None None None 116512214 Common - Glutathione peroxidase LACR_1499 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 116511961 Common - hypothetical protein LACR_1225 53 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 116511536 Common - alpha/beta superfamily hydrolase LACR_0772 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116511948 Common - GTP-binding protein LepA LACR_1210 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 116511783 Nonpathogen - hypothetical protein LACR_1039 1 None None None 116511778 Common - Transposase LACR_1034 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513166 Common - Predicted ATP-grasp enzyme LACR_2532 24 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 116512359 Common - hypothetical protein LACR_1656 50 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 116511606 Common - Putative NADH-flavin reductase LACR_0848 56 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 116512771 Common - Cell wall-associated hydrolase LACR_2088 10 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 116512026 Common - Transposase LACR_1292 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512487 Nonpathogen - hypothetical protein LACR_1787 1 None None None 116512765 Common - serine/threonine protein kinase, and beta-lactam (PASTA) domains LACR_2082 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 116512842 Common - Putative stress-responsive transcriptional regulator LACR_2164 4 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 116511112 Nonpathogen - hypothetical protein LACR_0298 1 None None None 116512664 Common - Negative regulator of genetic competence, sporulation and motility LACR_1976 14 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 116511745 Common - Transcriptional regulator LACR_0999 9 COG1316 LytR, Transcriptional regulator Transcription 116512580 Common - Parvulin-like peptidyl-prolyl isomerase LACR_1888 12 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 116513036 Common - Ribosomal protein S5 LACR_2384 230 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 116511268 Common - Superoxide dismutase LACR_0458 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 116510965 Common - RNase H-like ribonuclease LACR_0138 192 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 116512724 Common - Predicted hydrolase (HAD superfamily) LACR_2038 62 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116512833 Common - hypothetical protein LACR_2154 5 None None None 116511143 Common - Acetyltransferase LACR_0329 143 COG0456 RimI, Acetyltransferases General function prediction only 116511430 Common - Aminodeoxychorismate lyase family LACR_0659 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 116512506 Common - Thiol-disulfide isomerase or thioredoxin LACR_1808 227 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 116511297 Common truA tRNA pseudouridine synthase A LACR_0491 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 116512148 Common - Xaa-Pro aminopeptidase LACR_1428 9 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 116512396 Common obgE GTPase ObgE LACR_1694 249 COG0536 Obg, Predicted GTPase General function prediction only 116511242 Common - Membrane carboxypeptidase (penicillin-binding protein) LACR_0432 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 116513205 Nonpathogen - hypothetical protein LACR_2581 2 None None None 116512849 Common - Mn2+ and Fe2+ transporter of the NRAMP family LACR_2183 109 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 116512301 Common - aldose 1-epimerase LACR_1593 89 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 116513108 Common - Phosphopantetheine adenylyltransferase LACR_2464 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 116512742 Common - Cell division initiation protein LACR_2057 31 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 116511583 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase LACR_0824 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116511896 Common - redox-sensing transcriptional repressor Rex LACR_1156 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 116511207 Common - ABC-type oligopeptide transport system, ATPase component LACR_0394 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 116512760 Nonpathogen - hypothetical protein LACR_2077 1 None None None 116511562 Common engA GTP-binding protein EngA LACR_0799 230 COG1160 COG1160, Predicted GTPases General function prediction only 116511792 Common - hypothetical protein LACR_1049 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 116511483 Common - Mg-dependent DNase LACR_0715 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 116512863 Common - Predicted aspartate protease family domain LACR_2199 16 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 116511654 Common - Signal transduction histidine kinase LACR_0899 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116512350 Nonpathogen - hypothetical protein LACR_1647 1 None None None 116512630 Common - Predicted esterase LACR_1940 73 COG0627 COG0627, Predicted esterase General function prediction only 116512379 Common - Transposase LACR_1676 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512898 Common - Predicted Zn-dependent peptidase LACR_2236 128 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 116511951 Common - Transposase LACR_1214 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510897 Common - Predicted membrane protein LACR_0064 2 COG4682 COG4682, Predicted membrane protein Function unknown 116510844 Common dnaA chromosomal replication initiation protein LACR_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 116512061 Common - Imidazoleglycerol-phosphate dehydratase LACR_1331 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 116510907 Common - Lactoylglutathione lyase related lyase LACR_0074 36 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116512444 Common - glucuronate isomerase LACR_1742 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 116511803 Common nrdF ribonucleotide-diphosphate reductase subunit beta LACR_1060 103 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 116513151 Common ruvB Holliday junction DNA helicase B LACR_2515 232 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 116511021 Common - hypothetical protein LACR_0197 32 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 116512240 Common - Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein LACR_1527 106 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 116512207 Nonpathogen - hypothetical protein LACR_1492 1 None None None 116511507 Common - ABC-type transport system for cytochrome bd biosynthesis, ATPase and permease component LACR_0740 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 116511085 Common - Uncharacterized protein/domain associated with GTPase LACR_0267 11 COG3597 COG3597, Uncharacterized protein/domain associated with GTPases Function unknown 116512228 Common - Transposase LACR_1514 25 None None None 116511129 Nonpathogen - hypothetical protein LACR_0315 1 None None None 116512347 Common - dihydroorotate dehydrogenase 1A LACR_1644 142 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 116510885 Common - acetoin dehydrogenase complex, E1 component, alpha subunit LACR_0051 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 116511043 Common - UDP-galactopyranose mutase LACR_0219 61 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 116511352 Common - RNA polymerase sigma factor RpoD LACR_0571 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 116512493 Common - Holliday junction resolvase LACR_1793 3 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 116513127 Common - Acetyltransferase, GNAT family LACR_2485 17 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116512789 Common - hypothetical protein LACR_2108 12 None None None 116511301 Common - Serine-pyruvate aminotransferase LACR_0496 89 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 116511826 Common - Transposase LACR_1085 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512657 Common - ABC-type transport system for Fe-S cluster assembly, permease component LACR_1969 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 116511785 Common - Cation transport ATPase LACR_1042 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116512854 Common - NUDIX family hydrolase LACR_2190 13 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116511591 Common - Cysteine synthase LACR_0832 228 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 116513093 Common - Predicted O-methyltransferase LACR_2444 81 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 116511259 Common - Predicted methyltransferase LACR_0449 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 116510872 Nonpathogen - hypothetical protein LACR_0037 1 None None None 116511842 Common - Phage anti-repressor protein LACR_1101 11 None None None 116511308 Nonpathogen - hypothetical protein LACR_0503 1 None None None 116511621 Common - Phosphoglycerol transferase related protein, alkaline phosphatase superfamily LACR_0864 41 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 116511408 Common - hypothetical protein LACR_0635 5 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 116511015 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase LACR_0191 20 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 116512007 Common - GTPase EngB LACR_1273 187 COG0218 COG0218, Predicted GTPase General function prediction only 116513177 Common - Activator of 2-hydroxyglutaryl-CoA dehydratase and two uncharacterized domains LACR_2543 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 116512278 Common - permease of the drug/metabolite transporter (DMT) superfamily LACR_1569 40 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 116511448 Nonpathogen - hypothetical protein LACR_0677 2 None None None 116511956 Common - Lysyl-tRNA synthetase (class II) LACR_1219 150 COG2898 COG2898, Uncharacterized conserved protein Function unknown 116512590 Common - Lipid kinase from diacylglycerol kinase family LACR_1900 115 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 116511381 Common - Integrase LACR_0607 84 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116511003 Common - Predicted acetyltransferase LACR_0179 22 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 116512908 Common - Na+/xyloside symporter related transporter LACR_2246 62 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 116511595 Common - hypothetical protein, nickel resistance determinant LACR_0837 43 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 116512093 Nonpathogen - hypothetical protein LACR_1366 1 None None None 116511154 Common - aminopeptidase N LACR_0341 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 116511266 Common - Phosphomevalonate kinase LACR_0456 17 COG1577 ERG12, Mevalonate kinase Lipid metabolism 116511659 Common - Predicted transcriptional regulator LACR_0904 2 None None None 116511931 Common - hypothetical protein LACR_1193 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 116513015 Common - Transposase LACR_2360 27 None None None 116511541 Common - Phosphoesterase, DHH family protein LACR_0777 90 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 116512642 Common - hypothetical protein LACR_1953 100 COG1268 BioY, Uncharacterized conserved protein General function prediction only 116513168 Common - Surface antigen LACR_2534 10 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 116511546 Common - Membrane protease subunit, stomatin/prohibitin family LACR_0782 84 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 116512136 Common rnhB ribonuclease HII LACR_1415 215 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 116511273 Common - Transcriptional regulator LACR_0464 77 COG1737 RpiR, Transcriptional regulators Transcription 116511517 Common - NADPH:quinone reductase related Zn-dependent oxidoreductase LACR_0751 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116511388 Common - Methylase of polypeptide chain release factor LACR_0614 232 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 116511395 Common - Phosphoserine phosphatase LACR_0621 156 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 116512609 Common - hypothetical protein LACR_1919 69 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 116512755 Common - Predicted transcriptional regulator LACR_2072 92 COG0789 SoxR, Predicted transcriptional regulators Transcription 116511855 Nonpathogen - hypothetical protein LACR_1114 1 None None None 116510945 Common - Transposase LACR_0115 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512127 Common - Diaminopimelate decarboxylase LACR_1405 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 116511027 Nonpathogen - hypothetical protein LACR_0203 1 None None None 116511906 Common - Transposase LACR_1166 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512176 Common - 5-bromo-4-chloroindolyl phosphate hydrolysis protein LACR_1460 6 COG4915 XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein General function prediction only 116511997 Nonpathogen - hypothetical protein LACR_1263 1 None None None 116511847 Nonpathogen - hypothetical protein LACR_1106 1 None None None 116513028 Common - 30S ribosomal protein S11 LACR_2376 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 116512693 Nonpathogen - hypothetical protein LACR_2006 2 None None None 116511335 Common - Cell wall-associated hydrolase, YG repeats LACR_0535 12 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 116511032 Common - ABC-type polysaccharide/polyol phosphate export system, permease component LACR_0208 113 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 116512593 Common - ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member LACR_1903 144 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 116511724 Common - cell division membrane protein LACR_0972 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 116511818 Common - hypothetical protein LACR_1077 2 None None None 116512197 Common - hypothetical protein LACR_1482 20 None None None 116511893 Common - Lyzozyme M1 (1,4-beta-N-acetylmuramidase) LACR_1153 63 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 116512253 Nonpathogen - hypothetical protein LACR_1540 1 None None None 116510923 Common - hypothetical protein LACR_0090 186 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 116512163 Nonpathogen - hypothetical protein LACR_1447 1 None None None 116511187 Common - ABC-type Fe3+-hydroxamate transport system, periplasmic component LACR_0374 56 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 116513043 Common rplX 50S ribosomal protein L24 LACR_2391 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 116512059 Common hisH imidazole glycerol phosphate synthase subunit HisH LACR_1329 218 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 116512233 Common - hypothetical protein LACR_1519 7 None None None 116512151 Common - ABC-type maltose transport system, permease component LACR_1433 157 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116511062 Common - hypothetical protein LACR_0238 22 COG4832 COG4832, Uncharacterized conserved protein Function unknown 116513052 Common rplW 50S ribosomal protein L23 LACR_2400 146 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 116512078 Common - Predicted permease LACR_1351 196 COG0628 PerM, Predicted permease General function prediction only 116512113 Nonpathogen - hypothetical protein LACR_1389 1 None None None 116511718 Common - Signal transduction histidine kinase LACR_0966 150 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 116511341 Common - Membrane carboxypeptidase (penicillin-binding protein) LACR_0542 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 116511723 Common - hypothetical protein LACR_0971 23 COG0398 COG0398, Uncharacterized conserved protein Function unknown 116512325 Common - Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component LACR_1621 14 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 116512985 Nonpathogen - hypothetical protein LACR_2325 1 None None None 116512925 Common - hypothetical protein LACR_2263 2 None None None 116512994 Nonpathogen - hypothetical protein LACR_2336 1 None None None 116512362 Common rimM 16S rRNA-processing protein LACR_1659 148 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 116511708 Common - Universal stress protein UspA related nucleotide-binding protein LACR_0954 159 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116512285 Common - hypothetical protein LACR_1576 5 None None None 116511494 Common - Glucan phosphorylase LACR_0727 146 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 116511253 Common - Signal transduction histidine kinase LACR_0443 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 116510924 Common - Predicted xylanase/chitin deacetylase LACR_0091 105 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116512598 Common - prephenate dehydrogenase LACR_1908 158 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 116511216 Common - hypothetical protein LACR_0403 2 COG3679 COG3679, Uncharacterized conserved protein Function unknown 116511991 Common - Glycosyltransferase LACR_1257 9 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116512158 Common - hypothetical protein LACR_1442 5 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 116511910 Common - hypothetical protein LACR_1170 32 None None None 116512171 Common ldh L-lactate dehydrogenase LACR_1455 167 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 116511917 Common - HD superfamily phosphohydrolase LACR_1177 88 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 116513059 Common secE preprotein translocase subunit SecE LACR_2407 3 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 116511456 Common - Transposase LACR_0685 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510847 Common - ATP-dependent exoDNAse (exonuclease V) beta subunit LACR_0004 230 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 116511190 Common - Arabinose efflux permease LACR_0377 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512777 Nonpathogen - hypothetical protein LACR_2096 2 None None None 116511576 Common infB translation initiation factor IF-2 LACR_0817 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 116512338 Common - Transposase LACR_1635 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511139 Common - Predicted RNA binding protein, contains RRM domain LACR_0325 8 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 116510855 Common - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) LACR_0012 52 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 116513141 Common - Amino acid transporter LACR_2505 114 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 116511938 Common nadD nicotinic acid mononucleotide adenyltransferase LACR_1200 181 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 116511600 Common - Methyonyl-tRNA synthetase LACR_0842 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511872 Common - Phage terminase, small subunit LACR_1132 11 None None None 116511054 Common - RNA-binding protein containing KH domain LACR_0230 73 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 116511287 Common - Transcriptional regulator LACR_0480 84 COG2188 PhnF, Transcriptional regulators Transcription 116511279 Common ligA NAD-dependent DNA ligase LigA LACR_0472 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 116511002 Common - Lactoylglutathione lyase related lyase LACR_0178 19 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116511432 Common - Transposase LACR_0661 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512491 Nonpathogen - hypothetical protein LACR_1791 1 None None None 116513063 Common - Predicted membrane protein LACR_2411 28 COG2323 COG2323, Predicted membrane protein Function unknown 116513180 Nonpathogen - hypothetical protein LACR_2546 1 None None None 116512504 Common aroD 3-dehydroquinate dehydratase LACR_1805 54 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 116511370 Common - Cation transport ATPase LACR_0594 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116510908 Common - Conserved protein/domain typically associated with flavoprotein oxygenase, DIM6/NTAB family LACR_0075 77 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 116513009 Common - hypothetical protein LACR_2354 7 COG4817 COG4817, Uncharacterized protein conserved in bacteria Function unknown 116512711 Common - Rad3-related DNA helicase LACR_2024 200 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 116510989 Nonpathogen - hypothetical protein LACR_0164 1 None None None 116511609 Common - Transposase LACR_0852 71 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511217 Common - hypothetical protein LACR_0404 8 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 116511252 Nonpathogen - hypothetical protein LACR_0442 1 None None None 116512552 Common - Transcriptional regulator LACR_1859 59 COG1316 LytR, Transcriptional regulator Transcription 116513225 Common - SAM-dependent methyltransferase LACR_2602 28 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 116511686 Common - Predicted integral membrane protein LACR_0932 37 COG3548 COG3548, Predicted integral membrane protein Function unknown 116511346 Common - Archaeal fructose-1,6-bisphosphatase related enzyme of inositol monophosphatase family LACR_0547 181 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116511296 Common - Transcriptional regulator LACR_0489 61 COG1316 LytR, Transcriptional regulator Transcription 116511108 Common - hypothetical protein LACR_0292 4 None None None 116511368 Common - phosphopantothenate--cysteine ligase LACR_0592 203 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 116512168 Common - ABC-type uncharacterized transport system, ATPase component LACR_1452 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 116513113 Common pgi glucose-6-phosphate isomerase LACR_2470 208 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 116513201 Nonpathogen - hypothetical protein LACR_2577 1 None None None 116512826 Common - hypothetical protein LACR_2146 34 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 116512935 Common - hypothetical protein LACR_2273 5 None None None 116511183 Common - Predicted transcriptional regulator LACR_0370 61 COG1476 COG1476, Predicted transcriptional regulators Transcription 116511608 Common - Transposase LACR_0850 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511328 Common - nucleoid DNA-binding protein LACR_0525 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 116512648 Common - 3-oxoacyl-acyl carrier protein reductase LACR_1960 229 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116512395 Common - hypothetical protein LACR_1693 2 None None None 116513202 Nonpathogen - hypothetical protein LACR_2578 1 None None None 116511943 Common - ABC-type antimicrobial peptide transport system, ATPase component LACR_1205 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116512722 Common - Transposase LACR_2035 27 None None None 116512980 Common - carbamate kinase LACR_2319 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 116510952 Common - Argininosuccinate synthase LACR_0125 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 116512705 Common - Transposase LACR_2018 26 None None None 116512831 Common - hypothetical protein LACR_2151 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 116512413 Common - Xanthine/uracil permease LACR_1711 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 116511799 Common - Predicted phosphohydrolase LACR_1056 6 COG1409 Icc, Predicted phosphohydrolases General function prediction only 116511123 Common - hypothetical protein LACR_0309 2 None None None 116511321 Common - hypothetical protein LACR_0518 11 COG4990 COG4990, Uncharacterized protein conserved in bacteria Function unknown 116511227 Common - Membrane-associated lipoprotein for thiamine biosynthesis LACR_0414 119 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 116511852 Nonpathogen - hypothetical protein LACR_1111 1 None None None 116512446 Common - Na+/galactoside symporter LACR_1744 62 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 116512313 Common - Hypoxanthine-guanine phosphoribosyltransferase LACR_1606 153 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 116512441 Common - Transcriptional antiterminator LACR_1739 16 COG3711 BglG, Transcriptional antiterminator Transcription 116511582 Common - (acyl-carrier-protein) S-malonyltransferase LACR_0823 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 116511348 Nonpathogen - hypothetical protein LACR_0549 1 None None None 116511927 Common - Diacylglycerol kinase LACR_1187 101 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 116510948 Nonpathogen - hypothetical protein LACR_0119 1 None None None 116510960 Common - Predicted oxidoreductase LACR_0133 193 COG4989 COG4989, Predicted oxidoreductase General function prediction only 116510901 Common - O-acetylhomoserine sulfhydrylase LACR_0068 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 116510939 Common - hydrolase of the alpha/beta superfamily LACR_0109 58 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 116512865 Common pheS phenylalanyl-tRNA synthetase subunit alpha LACR_2201 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 116510930 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase LACR_0098 64 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 116511201 Common - UDP-N-acetylmuramyl pentapeptide synthase LACR_0388 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 116512352 Common - fhu operon transcription regulator LACR_1649 175 COG0583 LysR, Transcriptional regulator Transcription 116512393 Nonpathogen - hypothetical protein LACR_1691 1 None None None 116512063 Nonpathogen - hypothetical protein LACR_1334 1 None None None 116513100 Common rpsB 30S ribosomal protein S2 LACR_2455 247 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 116511219 Common - hypothetical protein LACR_0406 9 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 116513211 Common - ribonuclease HIII LACR_2587 32 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 116512843 Common - hypothetical protein LACR_2166 12 COG3595 COG3595, Uncharacterized conserved protein Function unknown 116511200 Common ddl D-alanyl-alanine synthetase A LACR_0387 226 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 116511246 Common - EMAP domain LACR_0436 196 COG0073 ARC1, EMAP domain General function prediction only 116511603 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase LACR_0845 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116512818 Nonpathogen - hypothetical protein LACR_2138 1 None None None 116513142 Common - DNA polymerase III subunits gamma and tau LACR_2506 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 116511736 Nonpathogen - hypothetical protein LACR_0988 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 116513107 Common - Predicted secreted protein woth PDZ domain and Lon-protease proteolytic domain LACR_2463 57 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 116512286 Common - hypothetical protein LACR_1577 7 None None None 116512490 Nonpathogen - hypothetical protein LACR_1790 1 None None None 116513097 Common - ComX LACR_2452 3 None None None 116511789 Common - Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase related enzyme LACR_1046 155 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 116511457 Common - ABC-type antimicrobial peptide transport system, ATPase component LACR_0686 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116512983 Common argS arginyl-tRNA synthetase LACR_2323 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511119 Nonpathogen - hypothetical protein LACR_0305 1 None None None 116512339 Common - Transcriptional regulator/sugar kinase LACR_1636 159 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116511489 Common - hypothetical protein LACR_0721 39 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 116511978 Common - sucrose-specific PTS system IIBC component LACR_1242 61 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 116512180 Common - Predicted membrane protein LACR_1464 22 COG4769 COG4769, Predicted membrane protein Function unknown 116512626 Common - F0F1-type ATP synthase, delta subunit LACR_1936 129 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 116511334 Common - Cysteine sulfinate desulfinase/cysteine desulfurase related enzyme LACR_0534 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 116512089 Common - Predicted transcriptional regulator LACR_1362 51 COG0789 SoxR, Predicted transcriptional regulators Transcription 116513041 Common rpsN 30S ribosomal protein S14 LACR_2389 197 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 116512103 Common - Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase LACR_1376 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 116513209 Common - ABC-type antimicrobial peptide transport system, permease component LACR_2585 33 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116511074 Common - Dihydroxyacetone kinase LACR_0250 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116512800 Nonpathogen - hypothetical protein LACR_2119 1 None None None 116511962 Common - fumarate reductase flavoprotein subunit LACR_1226 227 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 116511865 Nonpathogen - hypothetical protein LACR_1124 1 None None None 116512603 Common - ABC-type antimicrobial peptide transport system, ATPase component LACR_1913 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116512665 Common - ABC-type polar amino acid transport system, ATPase component LACR_1977 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116511651 Common rpsA 30S ribosomal protein S1 LACR_0896 231 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 116512556 Common - Phosphotransferase system, mannose/fructose-specific component IIA LACR_1863 81 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 116511317 Common - hypothetical protein LACR_0512 2 None None None 116512753 Common - Aldo/keto reductase of diketogulonate reductase family LACR_2068 154 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 116511538 Common - Isochorismate synthase LACR_0774 218 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116511531 Common - hypothetical protein LACR_0767 53 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 116512954 Common - Uridylate kinase LACR_2292 240 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 116512583 Common - Competence protein LACR_1891 14 COG4469 CoiA, Competence protein General function prediction only 116512662 Common - ABC-type transport system for Fe-S cluster assembly, ATPase component LACR_1974 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 116512880 Nonpathogen - hypothetical protein LACR_2218 1 None None None 116511743 Common - Transposase LACR_0996 27 None None None 116511145 Nonpathogen - hypothetical protein LACR_0331 1 None None None 116512170 Common - Uncharacterized ABC-type transport system, permease component LACR_1454 109 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 116511925 Common - ADP-ribose pyrophosphatase LACR_1185 73 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116512011 Nonpathogen - NUDIX family hydrolase LACR_1277 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116512185 Common - Dihydroorotate dehydrogenase LACR_1469 238 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 116511040 Common - glycosyltransferase LACR_0216 20 None None None 116512330 Common - hypothetical protein LACR_1626 7 COG4334 COG4334, Uncharacterized protein conserved in bacteria Function unknown 116511415 Common - 6-phosphogluconate dehydrogenase LACR_0642 181 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 116512381 Common - hypothetical protein LACR_1678 4 None None None 116511374 Nonpathogen - hypothetical protein LACR_0599 1 None None None 116511396 Common - Acylphosphatase LACR_0622 32 COG1254 AcyP, Acylphosphatases Energy production and conversion 116511807 Common - hypothetical protein LACR_1064 168 COG0344 COG0344, Predicted membrane protein Function unknown 116512179 Common - hypothetical protein LACR_1463 11 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 116512129 Common - Glutamate synthase LACR_1407 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 116513045 Common rpsQ 30S ribosomal protein S17 LACR_2393 223 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 116512936 Nonpathogen - hypothetical protein LACR_2274 1 None None None 116512015 Common - homoserine kinase LACR_1281 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 116511527 Common - ABC-type sugar transport system, periplasmic component LACR_0763 13 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116512118 Common - 16S rRNA uridine-516 pseudouridylate synthase related enzyme LACR_1396 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 116512469 Common - hypothetical protein LACR_1769 3 None None None 116511915 Nonpathogen - hypothetical protein LACR_1175 2 COG4918 COG4918, Uncharacterized protein conserved in bacteria Function unknown 116511646 Common - Cation transport ATPase LACR_0891 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116512131 Common - branched-chain amino acid aminotransferase LACR_1409 198 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 116512034 Common xerS site-specific tyrosine recombinase XerS LACR_1302 203 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116512533 Nonpathogen - hypothetical protein LACR_1839 1 None None None 116513088 Common - Trypsin-like serine protease, typically periplasmic with PDZ domain LACR_2439 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116513119 Common - Predicted transcriptional regulator LACR_2476 143 COG1733 COG1733, Predicted transcriptional regulators Transcription 116511064 Common - NADPH:quinone reductase related Zn-dependent oxidoreductase LACR_0240 127 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116513061 Common - Predicted acyltransferase LACR_2409 74 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116511564 Common - Transposase LACR_0801 27 None None None 116512249 Common - Transcriptional regulator, xre family LACR_1536 4 None None None 116512608 Common - hypothetical protein LACR_1918 8 COG4493 COG4493, Uncharacterized protein conserved in bacteria Function unknown 116512578 Common - Lysophospholipase L1 related esterase LACR_1886 48 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116512456 Common - hypothetical protein LACR_1755 2 COG5546 COG5546, Small integral membrane protein Function unknown 116510894 Common - fatty acid/phospholipid synthesis protein LACR_0061 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 116513163 Common - DnaJ-class molecular chaperone with C-terminal Zn finger domain LACR_2529 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 116511176 Common - acetoin reductase LACR_0363 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116512527 Nonpathogen - hypothetical protein LACR_1831 1 None None None 116512042 Common - acetolactate synthase catalytic subunit LACR_1311 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 116512282 Common - Transcriptional regulator LACR_1573 39 COG1846 MarR, Transcriptional regulators Transcription 116510871 Nonpathogen - hypothetical protein LACR_0036 1 None None None 116512421 Common - hypothetical protein LACR_1719 6 None None None 116512896 Common - XRE-family DNA-binding domain LACR_2234 51 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 116512675 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase LACR_1987 208 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 116510947 Common - hypothetical protein LACR_0118 5 None None None 116512141 Common - DNA segregation ATPase FtsK/SpoIIIE related protein LACR_1420 9 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 116511150 Common - ABC-type phosphate/phosphonate transport system, permease component LACR_0337 126 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 116511615 Common - Ornithine/acetylornithine aminotransferase LACR_0858 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 116512306 Common - Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase LACR_1599 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 116512796 Nonpathogen - hypothetical protein LACR_2115 1 None None None 116512978 Common - transaminase LACR_2317 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116511164 Nonpathogen - hypothetical protein LACR_0351 1 None None None 116510973 Nonpathogen - hypothetical protein LACR_0146 1 None None None 116512512 Nonpathogen - hypothetical protein LACR_1814 1 None None None 116512685 Common - hypothetical protein LACR_1997 3 None None None 116512479 Common - Phage terminase, small subunit LACR_1779 3 None None None 116511766 Common - Phosphoglycerate mutase family protein LACR_1022 111 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116510995 Common - Asp-tRNA-Asn/Glu-tRNA-Gln amidotransferase A subunit LACR_0170 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 116512962 Common - Transposase LACR_2300 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511086 Common - Predicted dehydrogenase related protein LACR_0268 130 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116512485 Common - dUTPase LACR_1785 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 116512050 Common - 3-isopropylmalate dehydrogenase LACR_1320 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 116511465 Common rpmG 50S ribosomal protein L33 LACR_0694 49 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 116511776 Common - tagatose-6-phosphate kinase LACR_1032 101 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 116512610 Common aroB 3-dehydroquinate synthase LACR_1920 211 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 116512913 Common - Collagenase related protease LACR_2251 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 116512922 Nonpathogen - hypothetical protein LACR_2260 1 None None None 116511508 Nonpathogen - hypothetical protein LACR_0741 1 None None None 116512701 Common - Thiamine pyrophosphokinase LACR_2014 40 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 116513051 Common rplB 50S ribosomal protein L2 LACR_2399 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 116511623 Common - Predicted multitransmembrane protein LACR_0866 17 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 116510861 Common - ATP-dependent Zn protease LACR_0018 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 116512809 Common - hypothetical protein LACR_2129 8 COG4712 COG4712, Uncharacterized protein conserved in bacteria Function unknown 116512929 Nonpathogen - Phage related anti-repressor protein LACR_2267 1 None None None 116513081 Common - prolyl-tRNA synthetase LACR_2432 243 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511090 Common - Aldo/keto reductase of diketogulonate reductase family LACR_0272 200 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 116511884 Common - hypothetical protein LACR_1144 5 None None None 116510918 Common - ATPase component of ABC transporter with duplicated ATPase domains LACR_0085 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116512192 Common - ABC-type maltose transport system, permease component LACR_1476 162 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116513175 Common - Universal stress protein UspA related nucleotide-binding protein LACR_2541 97 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116511498 Nonpathogen - hypothetical protein LACR_0731 1 None None None 116512856 Common - Galactose mutarotase related enzyme LACR_2192 47 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 116513158 Common - Predicted membrane protein LACR_2524 11 COG4272 COG4272, Predicted membrane protein Function unknown 116510896 Common - ATPase component of ABC transporter with duplicated ATPase domains LACR_0063 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116511936 Common - hypothetical protein LACR_1198 17 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 116511059 Common - SAM-dependent methyltransferase LACR_0235 124 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116512109 Nonpathogen - hypothetical protein LACR_1385 1 None None None 116511597 Common - Transcriptional regulator of sugar metabolism LACR_0839 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 116511290 Common - Trehalose and maltose hydrolase (possible phosphorylase) LACR_0483 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 116512470 Common - hypothetical protein LACR_1770 5 None None None 116512264 Common trpC indole-3-glycerol-phosphate synthase LACR_1552 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 116511383 Nonpathogen - hypothetical protein LACR_0609 1 None None None 116511130 Common - hypothetical protein LACR_0316 39 None None None 116511952 Common - Type I restriction-modification system methyltransferase subunit LACR_1215 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 116512874 Common - Predicted membrane protein LACR_2212 15 COG3152 COG3152, Predicted membrane protein Function unknown 116512992 Common - Beta-lactamase class C related penicillin binding protein LACR_2334 91 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 116512639 Common - Putative transcription activator LACR_1950 76 COG0819 TenA, Putative transcription activator Transcription 116512369 Common - 3-hydroxy-3-methylglutaryl CoA synthase LACR_1666 59 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 116512920 Common - Phage DNA polymerase (ATPase domain) LACR_2258 38 COG3378 COG3378, Predicted ATPase General function prediction only 116513185 Common - Transcriptional regulator, xre family LACR_2551 6 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 116511323 Common - Predicted membrane protein, hemolysin IIIrelated protein LACR_0520 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 116511628 Common - hypothetical protein LACR_0871 3 None None None 116512365 Common - Predicted RNA-binding protein, KH domain LACR_1662 4 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 116511009 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase LACR_0185 175 COG0756 Dut, dUTPase Nucleotide transport and metabolism 116512927 Nonpathogen - hypothetical protein LACR_2265 1 None None None 116512269 Nonpathogen - hypothetical protein LACR_1557 1 None None None 116511721 Common - Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family LACR_0969 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 116512153 Common - hypothetical protein LACR_1436 15 None None None 116512713 Common - ABC-type oligopeptide transport system, periplasmic component LACR_2026 173 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116511890 Nonpathogen - hypothetical protein LACR_1150 1 None None None 116511886 Common - Minor tail protein gp26-like protein LACR_1146 30 COG5412 COG5412, Phage-related protein Function unknown 116511250 Common groEL chaperonin GroEL LACR_0440 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 116511445 Nonpathogen - hypothetical protein LACR_0674 1 None None None 116511683 Common - Arginine repressor LACR_0929 34 COG1438 ArgR, Arginine repressor Transcription 116511674 Common - Cation transport ATPase LACR_0920 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116512323 Common - Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain LACR_1619 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 116511578 Common - Phosphomannose isomerase LACR_0819 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 116512778 Nonpathogen - hypothetical protein LACR_2097 2 None None None 116511157 Common - Predicted Co/Zn/Cd cation transporter LACR_0344 201 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 116512294 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase LACR_1586 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116511025 Nonpathogen - hypothetical protein LACR_0201 1 None None None 116512111 Common rplJ 50S ribosomal protein L10 LACR_1387 216 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 116512741 Common ileS isoleucyl-tRNA synthetase LACR_2056 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511492 Common glgC glucose-1-phosphate adenylyltransferase LACR_0724 214 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 116512948 Common - ABC-type multidrug transport system, ATPase component LACR_2286 247 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116513183 Common - Serine/threonine protein kinase LACR_2549 8 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 116513018 Common - Glycosyltransferase LACR_2363 216 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116511819 Common - Predicted transcriptional regulator LACR_1078 35 COG2378 COG2378, Predicted transcriptional regulator Transcription 116512734 Common - hypothetical protein LACR_2048 2 None None None 116511343 Common - hypothetical protein LACR_0544 11 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 116512857 Common - Predicted HD-superfamily hydrolase LACR_2193 47 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 116511968 Nonpathogen - hypothetical protein LACR_1232 1 None None None 116512304 Common - AraC-like transcriptional regulator (HTH and ligand binding domain) LACR_1597 125 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116513220 Common rpsL 30S ribosomal protein S12 LACR_2597 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 116512146 Common - Acetyltransferase (GNAT) family LACR_1425 7 None None None 116512850 Common - Oxidoreductase LACR_2184 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 116512499 Common - ABC-type sugar transport system, ATPase component LACR_1800 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116512766 Common - Serine/threonine protein phosphatase LACR_2083 138 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 116511985 Nonpathogen - hypothetical protein LACR_1251 1 None None None 116511806 Common - Glutaredoxin related protein LACR_1063 29 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 116511525 Common - ABC-type polysaccharide transport system, permease component LACR_0761 140 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 116513114 Nonpathogen - hypothetical protein LACR_2471 1 None None None 116511476 Common - Transposase LACR_0708 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511480 Common - Branched-chain amino acid permease LACR_0712 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 116512871 Common - Predicted permease, cadmium resistance protein LACR_2208 8 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 116512514 Common - Predicted N6-adenine-specific DNA methylase LACR_1816 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 116513069 Common - ABC-type Mn2+/Zn2+ transport system, permease component LACR_2417 193 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 116512546 Common - ABC-type sugar transport system, periplasmic component LACR_1853 75 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 116512883 Common - tRNA-dihydrouridine synthase LACR_2221 216 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 116511519 Nonpathogen - hypothetical protein LACR_0754 1 None None None 116510968 Common - carbonyl reductase LACR_0141 212 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116511275 Common - cellobiose-specific PTS system IIA component LACR_0466 29 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 116510878 Common - Sulfate permease related transporter (MFS superfamily) LACR_0043 110 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 116513023 Common - Glycosyltransferase LACR_2370 212 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116513167 Common - Asparagine synthase (glutamine-hydrolyzing) LACR_2533 173 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 116512027 Common - Transposase LACR_1293 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513077 Common - Transposase LACR_2428 27 None None None 116511570 Common - Putative effector of murein hydrolase LACR_0811 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 116511874 Common - Phage portal protein, SPP1 Gp6-like LACR_1134 8 None None None 116511406 Common - Ribonuclease BN-like family enzyme LACR_0632 59 COG1295 Rbn, Predicted membrane protein Function unknown 116512903 Common - alpha/beta hydrolase superfamily protein LACR_2241 6 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 116512172 Common - pyruvate kinase LACR_1456 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 116510978 Nonpathogen - hypothetical protein LACR_0152 1 None None None 116512315 Common - ABC-type multidrug transport system, ATPase and permease component LACR_1609 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116512258 Common - beta-glucoside operon antiterminator LACR_1546 29 COG3711 BglG, Transcriptional antiterminator Transcription 116511133 Common - Transcriptional accessory protein LACR_0319 200 COG2183 Tex, Transcriptional accessory protein Transcription 116512687 Common - Pyruvate-formate lyase-activating enzyme LACR_1999 96 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 116513099 Common tsf elongation factor Ts LACR_2454 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 116511000 Common - Membrane-associated serine protease LACR_0176 112 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 116511181 Common - ABC-type cobalt transport system, ATPase component LACR_0368 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 116511726 Nonpathogen - hypothetical protein LACR_0975 1 None None None 116510929 Common - Amino acid transporter LACR_0097 156 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 116511836 Common - DNA repair protein LACR_1095 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 116512714 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component LACR_2027 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116511210 Common era GTP-binding protein Era LACR_0397 239 COG1159 Era, GTPase General function prediction only 116513003 Common - Amidase LACR_2347 47 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116511358 Common - Glyceraldehyde-3-phosphate dehydrogenase LACR_0580 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 116512655 Nonpathogen - hypothetical protein LACR_1967 2 None None None 116511195 Common - Phosphoglycerate mutase 1 LACR_0382 152 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 116512020 Common - spermidine/putrescine ABC transporter permease protein LACR_1286 215 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116512201 Common - Glycerol-3-phosphate dehydrogenase LACR_1486 159 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 116511547 Common - aspartate kinase LACR_0783 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 116511188 Common - fhu operon transcription regulator LACR_0375 185 COG0583 LysR, Transcriptional regulator Transcription 116511366 Common - Predicted hydrolase of the HAD superfamily LACR_0589 5 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116511999 Common - xanthine phosphoribosyltransferase LACR_1265 101 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 116510984 Common tgt queuine tRNA-ribosyltransferase LACR_0159 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 116511361 Common - excinuclease ABC subunit B LACR_0583 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 116511105 Common - ABC-type cobalt transport system, ATPase component LACR_0289 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 116511558 Common - Replication initiation/membrane attachment protein LACR_0795 15 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 116512165 Nonpathogen - hypothetical protein LACR_1449 1 None None None 116512824 Nonpathogen - hypothetical protein LACR_2144 2 None None None 116512939 Common - Predicted ABC-type exoprotein transport system, permease component LACR_2277 12 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 116512699 Common - Gamma-aminobutyrate permease related permease LACR_2012 129 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 116511712 Common - Predicted membrane protein LACR_0959 31 COG1511 COG1511, Predicted membrane protein Function unknown 116513132 Common - gluconate kinase LACR_2496 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 116512651 Common - hypothetical protein LACR_1963 2 None None None 116512232 Nonpathogen - hypothetical protein LACR_1518 1 None None None 116512595 Common - prephenate dehydratase LACR_1905 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 116512083 Common - N-acetylmannosamine-6-phosphate 2-epimerase LACR_1356 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 116510926 Common - D-tyrosyl-tRNA deacylase LACR_0094 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 116511257 Common - Regulator of signaling phosphorelay (PSP1/tpl family) LACR_0447 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 116511638 Common - Transposase LACR_0883 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511175 Common - ABC-type metal ion transport system, periplasmic component/surface antigen LACR_0362 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 116512341 Common - ribose-5-phosphate isomerase B LACR_1638 129 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 116511413 Common - Methyl-accepting chemotaxis-like domain containing protein LACR_0640 7 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 116512780 Nonpathogen - hypothetical protein LACR_2099 2 None None None 116513125 Common - hypothetical protein LACR_2483 2 None None None 116511748 Common - Purine-nucleoside phosphorylase LACR_1003 92 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 116512076 Common - acetolactate synthase LACR_1349 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 116511097 Nonpathogen - hypothetical protein LACR_0280 1 None None None 116512839 Common - putative 6-phosphogluconolactonase LACR_2160 86 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 116510954 Common - permease of the major facilitator superfamily LACR_0127 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511450 Common - Transposase LACR_0679 27 None None None 116513193 Common - Short-chain alcohol dehydrogenase LACR_2559 99 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116512606 Common - chorismate synthase LACR_1916 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 116513123 Nonpathogen - hypothetical protein LACR_2480 1 None None None 116513092 Nonpathogen - hypothetical protein LACR_2443 1 None None None 116511553 Common - Replicative DNA helicase LACR_0790 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 116511261 Common - ABC-type multidrug transport system, permease component LACR_0451 110 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 116510880 Common - aromatic amino acid aminotransferase LACR_0046 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116511664 Common alr alanine racemase LACR_0910 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 116511593 Common - Rhodanese-related sulfurtransferase LACR_0834 136 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 116512892 Nonpathogen - hypothetical protein LACR_2230 1 None None None 116512229 Common - hypothetical protein LACR_1515 20 COG1511 COG1511, Predicted membrane protein Function unknown 116511973 Common truB tRNA pseudouridine synthase B LACR_1237 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 116512209 Common - Transposase LACR_1494 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511124 Nonpathogen - hypothetical protein LACR_0310 1 None None None 116512244 Common - pyrimidine-nucleoside phosphorylase LACR_1531 119 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 116513055 Common mscL large-conductance mechanosensitive channel LACR_2403 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116512759 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase LACR_2076 96 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 116511048 Common - hypothetical protein LACR_0224 12 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 116511066 Common - Saccharopine dehydrogenase related protein LACR_0242 208 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116511199 Common - Recombinational DNA repair protein (RecF pathway) LACR_0386 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 116513178 Common - Transcriptional regulator LACR_2544 31 COG1309 AcrR, Transcriptional regulator Transcription 116512415 Common - hypothetical protein LACR_1713 6 None None None 116512660 Common - Cysteine sulfinate desulfinase/cysteine desulfurase related enzyme LACR_1972 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 116511691 Common - Cell division protein FtsI/penicillin-binding protein 2 LACR_0937 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 116512774 Common - hypothetical protein LACR_2093 4 None None None 116511929 Common - Predicted amidophosphoribosyltransferase LACR_1189 69 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 116513145 Common - hypothetical protein LACR_2509 5 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 116512683 Common - Amino acid transporter LACR_1995 68 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 116511487 Common - aminopeptidase P LACR_0719 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 116511212 Common - formamidopyrimidine-DNA glycosylase LACR_0399 183 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 116511434 Common - Transposase LACR_0663 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511307 Nonpathogen - hypothetical protein LACR_0502 1 None None None 116510975 Common - Predicted outer membrane protein LACR_0149 29 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 116512288 Nonpathogen - Predicted integral membrane protein LACR_1579 1 COG5578 COG5578, Predicted integral membrane protein Function unknown 116512624 Common - F0F1 ATP synthase subunit gamma LACR_1934 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 116512973 Common - Type II secretory pathway, prepilin signal peptidase PulO related peptidase LACR_2312 49 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116512751 Common - Transposase LACR_2066 26 None None None 116511711 Common - Transposase LACR_0958 26 None None None 116511790 Common - hypothetical protein LACR_1047 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 116511013 Common - Nitroreductase LACR_0189 76 COG0778 NfnB, Nitroreductase Energy production and conversion 116512670 Common - Pleiotropic transcriptional repressor LACR_1982 19 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 116511357 Common - Predicted transcriptional regulator LACR_0579 71 COG1959 COG1959, Predicted transcriptional regulator Transcription 116512938 Common - Uncharacterized protein for copper resistance LACR_2276 56 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 116512585 Common - Xanthine/uracil/vitamin C permease LACR_1894 136 COG2252 COG2252, Permeases General function prediction only 116510851 Common - Transcriptional regulator, xre family LACR_0008 25 COG1476 COG1476, Predicted transcriptional regulators Transcription 116512959 Nonpathogen - hypothetical protein LACR_2297 1 None None None 116513048 Common rpsC 30S ribosomal protein S3 LACR_2396 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 116511567 Nonpathogen - hypothetical protein LACR_0805 5 None None None 116511738 Common - N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase related protein LACR_0991 5 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 116512545 Common - neopullulanase LACR_1852 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116511867 Nonpathogen - hypothetical protein LACR_1126 1 None None None 116512952 Common - Acetyltransferase, GNAT family LACR_2290 16 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116511741 Common - Lipopolysaccharide biosynthesis glycosyltransferase LACR_0994 24 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 116512769 Common - Glycosyltransferase LACR_2086 204 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116513085 Common - Preprotein translocase subunit YajC LACR_2436 9 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 116512002 Common - Predicted rRNA methylase (SpoU class) LACR_1268 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 116511417 Common - K+ transporter LACR_0644 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 116511964 Nonpathogen - Phosphotransferase enzyme family LACR_1228 1 None None None 116511700 Common - Ketosteroid isomerase related protein LACR_0946 7 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 116512144 Nonpathogen - hypothetical protein LACR_1423 1 None None None 116512401 Common - Ammonia permease LACR_1699 191 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 116511716 Common - Transposase LACR_0963 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511797 Common - Formate/nitrite family of transporter LACR_1054 92 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 116511148 Common - ABC-type phosphate/phosphonate transport system, ATPase component LACR_0335 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 116512916 Common - SAM-dependent methyltransferase LACR_2254 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116511774 Common - Metal-dependent amidase/aminoacylase/carboxypeptidase LACR_1030 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 116510937 Common - hypothetical protein LACR_0106 101 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 116512434 Common - Glycerol uptake facilitator related permease (Major Intrinsic Protein Family) LACR_1732 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 116512483 Nonpathogen - hypothetical protein LACR_1783 1 None None None 116512156 Common - ABC-type Mn/Zn transport system, ATPase component LACR_1440 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 116513005 Common - fhu operon transcription regulator LACR_2349 144 COG0583 LysR, Transcriptional regulator Transcription 116512354 Nonpathogen - hypothetical protein LACR_1651 1 None None None 116511658 Common - A/G-specific DNA glycosylase LACR_0903 238 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 116511897 Common - Arsenate reductase related protein, glutaredoxin family LACR_1157 43 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116511584 Common - 3-oxoacyl-(acyl-carrier-protein) synthase LACR_0825 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116510903 Common - Transposase LACR_0070 26 None None None 116512728 Common - Ribonuclease III family protein LACR_2042 37 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 116511556 Common trmB tRNA (guanine-N(7))-methyltransferase LACR_0793 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 116513155 Common - DNA mismatch repair protein LACR_2519 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 116512845 Common - fructose-bisphosphate aldolase LACR_2168 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 116511203 Common - ABC-type oligopeptide transport system, periplasmic component LACR_0390 180 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 116512727 Common - hypothetical protein LACR_2041 5 COG4699 COG4699, Uncharacterized protein conserved in bacteria Function unknown 116512391 Common - cell surface protein LACR_1689 7 None None None 116513105 Nonpathogen - hypothetical protein LACR_2460 1 None None None 116512443 Common - 2-dehydro-3-deoxygluconokinase LACR_1741 158 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116512040 Common - ketol-acid reductoisomerase LACR_1309 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 116511586 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase LACR_0827 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 116512540 Common - maltosephosphorylase LACR_1847 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 116512525 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase LACR_1829 20 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 116511613 Common argC N-acetyl-gamma-glutamyl-phosphate reductase LACR_0856 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 116512999 Common - Glycerol uptake facilitator related permease (Major Intrinsic Protein Family) LACR_2341 109 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 116511473 Common - hypothetical protein LACR_0704 6 COG3371 COG3371, Predicted membrane protein Function unknown 116512123 Common - Predicted phosphoesterase LACR_1401 52 COG0622 COG0622, Predicted phosphoesterase General function prediction only 116513021 Common - Membrane protein for polysaccharide transport LACR_2367 14 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116512276 Common - Uncharacterized membrane protein LACR_1567 77 COG1814 COG1814, Uncharacterized membrane protein Function unknown 116511315 Common - L-2-hydroxyisocaproate/malate/lactate dehydrogenase LACR_0510 153 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 116511821 Common - Transposase LACR_1080 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513194 Nonpathogen - hypothetical protein LACR_2560 1 None None None 116511166 Common - Transposase LACR_0353 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512792 Nonpathogen - hypothetical protein LACR_2111 1 None None None 116511225 Common - Amino acid transporter LACR_0412 135 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 116512794 Nonpathogen - hypothetical protein LACR_2113 1 None None None 116511061 Common - hypothetical protein LACR_0237 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 116512976 Common - hypothetical protein LACR_2315 25 COG3760 COG3760, Uncharacterized conserved protein Function unknown 116511410 Nonpathogen - hypothetical protein LACR_0637 1 None None None 116510996 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B LACR_0171 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 116512703 Nonpathogen - hypothetical protein LACR_2016 1 None None None 116511467 Common - pyruvate carboxylase LACR_0696 242 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 116512503 Common - adenylosuccinate lyase LACR_1804 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 116511231 Common - Predicted membrane protein LACR_0419 119 COG2855 COG2855, Predicted membrane protein Function unknown 116512738 Common - hypothetical protein LACR_2053 7 None None None 116511753 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain LACR_1009 125 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116513037 Common - Ribosomal protein L18 LACR_2385 151 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 116511632 Common - Transcriptional regulator LACR_0876 84 COG1737 RpiR, Transcriptional regulators Transcription 116511520 Common - Cold shock protein LACR_0755 170 COG1278 CspC, Cold shock proteins Transcription 116512472 Common - hypothetical protein LACR_1772 5 None None None 116513173 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase LACR_2539 32 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116512191 Nonpathogen - hypothetical protein LACR_1475 1 None None None 116511764 Common - hypothetical protein LACR_1020 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 116512049 Common - ADP-ribose pyrophosphatase LACR_1319 14 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116511376 Nonpathogen - hypothetical protein LACR_0601 1 None None None 116512455 Common - Lyzozyme M1 (1,4-beta-N-acetylmuramidase) LACR_1754 64 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 116512013 Common - Deoxynucleoside kinase LACR_1279 40 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 116511099 Nonpathogen - hypothetical protein LACR_0282 1 None None None 116511758 Common secG preprotein translocase subunit SecG LACR_1014 11 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 116513076 Common - Competence protein ComGC LACR_2425 8 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 116512731 Common - Serine acetyltransferase LACR_2045 190 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 116511809 Nonpathogen - Amidase LACR_1066 1 None None None 116511850 Nonpathogen - RecG-like helicase LACR_1109 1 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 116512332 Common - permease of the major facilitator superfamily LACR_1628 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512290 Common - ABC-type sugar transport system, permease component LACR_1581 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116511224 Common - Peptidyl-prolyl cis-trans isomerase, cyclophilin family LACR_0411 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 116512601 Common - Glycopeptide antibiotics resistance protein LACR_1911 8 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 116512551 Common - Amidase LACR_1858 80 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116512807 Common - hypothetical protein LACR_2127 10 None None None 116511901 Common - TPR repeat containing protein LACR_1161 80 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 116512036 Common - DNA topoisomerase I LACR_1304 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 116511529 Common - Alpha-glucosidase, family 31 of glycosyl hydrolase LACR_0765 79 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 116512057 Common - Imidazoleglycerol-phosphate synthase LACR_1327 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 116511678 Common - Transposase LACR_0924 26 None None None 116512495 Nonpathogen - hypothetical protein LACR_1795 1 None None None 116512067 Common - Transposase LACR_1339 27 None None None 116512618 Common - Transposase LACR_1928 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512967 Nonpathogen - hypothetical protein LACR_2305 1 None None None 116511908 Nonpathogen - hypothetical protein LACR_1168 1 None None None 116512448 Common - Fructuronate reductase LACR_1746 75 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 116512116 Common - hypothetical protein LACR_1393 25 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 116512410 Common - Surface antigen LACR_1708 5 None None None 116512637 Common - Sortase related acyltransferase LACR_1948 93 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116512408 Common - Predicted phosphohydrolase LACR_1706 99 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 116512990 Common - Transposase LACR_2330 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510941 Nonpathogen - hypothetical protein LACR_0111 1 None None None 116512017 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase LACR_1283 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 116511336 Common - ABC-type oligopeptide transport system, periplasmic component LACR_0536 167 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 116511117 Nonpathogen - Predicted transcriptional regulator LACR_0303 3 COG3655 COG3655, Predicted transcriptional regulator Transcription 116510892 Common - Predicted redox protein, regulator of disulfide bond formation LACR_0059 66 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116511047 Common - Surface antigen LACR_0223 9 None None None 116512574 Common - ABC-type phosphate transport system, periplasmic component LACR_1882 100 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 116511729 Common - permease of the drug/metabolite transporter (DMT) superfamily LACR_0979 50 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116511485 Common - Ribonuclease M5 (Toprim domain) LACR_0717 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 116512537 Common - Signal transduction histidine kinase LACR_1844 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116512467 Common - hypothetical protein LACR_1767 5 None None None 116512389 Common - cell surface protein LACR_1687 8 None None None 116511422 Common - Membrane protease subunit, stomatin/prohibitin family LACR_0649 195 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 116512565 Nonpathogen - hypothetical protein LACR_1873 1 None None None 116511031 Common - Glycosyltransferase LACR_0207 110 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116512535 Common - hypothetical protein LACR_1842 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 116511429 Common - DNA-directed RNA polymerase, delta subunit LACR_0658 14 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 116511648 Common - Predicted membrane protein LACR_0893 11 COG4485 COG4485, Predicted membrane protein Function unknown 116511859 Nonpathogen - hypothetical protein LACR_1118 1 None None None 116513161 Common - glucose-6-phosphate 1-dehydrogenase LACR_2527 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 116512558 Common - mannose-specific PTS system component IID LACR_1865 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 116512060 Common - Aminoglycoside phosphotransferase LACR_1330 14 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 116512890 Common hisS histidyl-tRNA synthetase LACR_2228 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116512673 Common - Predicted methylated DNA-protein cysteine methyltransferase LACR_1985 35 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 116511887 Common - hypothetical protein LACR_1147 6 COG4722 COG4722, Phage-related protein Function unknown 116511681 Common - Acetyltransferase, GNAT family LACR_0927 12 COG0456 RimI, Acetyltransferases General function prediction only 116511880 Common - hypothetical protein LACR_1140 3 None None None 116512299 Common - Transposase LACR_1591 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512217 Nonpathogen - hypothetical protein LACR_1503 3 None None None 116512941 Common - Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase LACR_2279 77 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 116511299 Common - Predicted membrane protein LACR_0493 13 COG4720 COG4720, Predicted membrane protein Function unknown 116513138 Common - single-strand DNA-binding protein LACR_2502 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 116512321 Common - hypothetical protein LACR_1615 2 None None None 116512969 Common - hypothetical protein LACR_2308 5 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 116513153 Common mutL DNA mismatch repair protein LACR_2517 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 116512733 Common - polynucleotide phosphorylase/polyadenylase LACR_2047 235 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 116512616 Nonpathogen - hypothetical protein LACR_1926 1 None None None 116512508 Common - Predicted membrane ancor connecting MutS2 with cell-division Z-ring LACR_1810 10 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 116512587 Common - Fe-S oxidoreductase LACR_1896 167 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 116512773 Nonpathogen - hypothetical protein LACR_2091 1 None None None 116511762 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase LACR_1018 14 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 116512852 Common - Kef-type K+ transport system, membrane component LACR_2186 212 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 116511238 Common - Predicted redox protein, regulator of disulfide bond formation LACR_0428 50 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116511263 Common - Transcriptional regulator LACR_0453 51 COG1846 MarR, Transcriptional regulators Transcription 116512055 Common - Histidinol phosphatase related hydrolase of the PHP family LACR_1325 35 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 116512782 Nonpathogen - hypothetical protein LACR_2101 2 None None None 116511478 Common - Transposase LACR_0710 26 None None None 116511983 Common - coproporphyrinogen III oxidase LACR_1249 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 116513067 Common - Transposase LACR_2415 140 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513222 Nonpathogen - hypothetical protein LACR_2599 1 None None None 116512210 Nonpathogen - cell surface protein LACR_1495 2 None None None 116512074 Common - Predicted transcriptional regulator LACR_1347 124 COG1733 COG1733, Predicted transcriptional regulators Transcription 116511490 Common - Transcription termination factor LACR_0722 165 COG0781 NusB, Transcription termination factor Transcription 116511800 Common - Protein chain release factor B LACR_1057 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 116512183 Nonpathogen - hypothetical protein LACR_1467 1 None None None 116511050 Common - Predicted GTPase LACR_0226 22 COG1161 COG1161, Predicted GTPases General function prediction only 116510914 Common - ParB-like nuclease domain LACR_0081 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 116511812 Common - Acetyltransferase, GNAT family LACR_1069 90 COG2153 ElaA, Predicted acyltransferase General function prediction only 116511471 Common spxA transcriptional regulator Spx LACR_0702 36 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116511876 Nonpathogen - hypothetical protein LACR_1136 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 116512806 Nonpathogen - hypothetical protein LACR_2126 1 None None None 116511022 Common - Ribosomal protein L28 LACR_0198 26 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 116512521 Common eutD phosphotransacetylase LACR_1824 165 COG0280 Pta, Phosphotransacetylase Energy production and conversion 116511292 Common - Esterase/lipase LACR_0485 37 COG0657 Aes, Esterase/lipase Lipid metabolism 116511599 Common - Exonuclease III LACR_0841 194 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 116513214 Common - purine operon repressor LACR_2590 45 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 116511345 Common - hypothetical protein LACR_0546 11 COG4476 COG4476, Uncharacterized protein conserved in bacteria Function unknown 116512095 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase LACR_1368 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 116511551 Common - Signaling protein (consists of PAS, a modified GGDEF and a DHH family phosphatase domains) LACR_0788 55 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 116512065 Common - histidinol-phosphate aminotransferase LACR_1336 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 116511436 Common - Transcriptional repressor of class III stress genes LACR_0665 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 116512501 Common - Sugar kinase, ribokinase family LACR_1802 190 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116511325 Common - Lysophospholipase L1 related esterase LACR_0522 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116512378 Nonpathogen - hypothetical protein LACR_1675 1 None None None 116512367 Common - Hydroxymethylglutaryl-CoA reductase LACR_1664 56 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 116511159 Common - ABC-type multidrug transport system, ATPase and permease component LACR_0346 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116511256 Common - DNA polymerase III subunit delta' LACR_0446 208 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 116512319 Nonpathogen - hypothetical protein LACR_1613 1 None None None 116512302 Common - Xylanase LACR_1595 8 None None None 116512989 Common - Transposase LACR_2329 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512708 Nonpathogen - hypothetical protein LACR_2021 1 None None None 116511714 Common - Transposase LACR_0961 49 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512343 Common - Sugar metabolism regulatory protein, HTH and periplasmic binding domains LACR_1640 128 COG1609 PurR, Transcriptional regulators Transcription 116511072 Common pgk phosphoglycerate kinase LACR_0248 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 116511992 Nonpathogen - hypothetical protein LACR_1258 1 None None None 116512262 Common - Acetyltransferase, including N-acetylase of ribosomal protein LACR_1550 12 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116512155 Common - ABC-type Mn2+/Zn2+ transport system, permease component LACR_1439 186 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 116511746 Common - phosphopentomutase LACR_1001 71 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 116511088 Common - S-ribosylhomocysteinase LACR_0270 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 116511662 Common - dipeptidase PepV LACR_0908 158 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 116513130 Common - hypothetical protein LACR_2489 4 None None None 116510882 Common - dihydrolipoamide dehydrogenase LACR_0048 237 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 116512653 Common - Transposase LACR_1965 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511442 Common - hypothetical protein LACR_0671 2 None None None 116512837 Common gmk guanylate kinase LACR_2158 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 116512081 Common - tRNA (uracil-5-)-methyltransferase related enzyme LACR_1354 200 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 116512238 Nonpathogen - hypothetical protein LACR_1525 2 None None None 116511160 Common - ABC-type multidrug transport system, ATPase and permease component LACR_0347 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116512747 Common - cell division protein FtsZ LACR_2062 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 116511170 Common - hypothetical protein LACR_0357 82 COG1268 BioY, Uncharacterized conserved protein General function prediction only 116511385 Nonpathogen - hypothetical protein LACR_0611 1 None None None 116511604 Nonpathogen - hypothetical protein LACR_0846 1 None None None 116511006 Nonpathogen - hypothetical protein LACR_0182 2 None None None 116511355 Nonpathogen - Serine-pyruvate aminotransferase LACR_0577 1 None None None 116512221 Common - hypothetical protein LACR_1507 8 None None None 116512784 Common - hypothetical protein LACR_2103 4 None None None 116511095 Common - Organic radical activating enzyme LACR_0278 64 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 116513116 Common - Short-chain alcohol dehydrogenase LACR_2473 105 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116512274 Common - Methylase for ubiquinone/menaquinone biosynthesis LACR_1565 9 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116513121 Nonpathogen - hypothetical protein LACR_2478 1 None None None 116512716 Common - ABC-type oligopeptide transport system, ATPase component LACR_2029 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 116513090 Common - Glycosyltransferase LACR_2441 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116512309 Common - Transcriptional regulator LACR_1602 24 COG1309 AcrR, Transcriptional regulator Transcription 116510876 Nonpathogen - Predicted membrane protein LACR_0041 3 COG2314 XynA, Predicted membrane protein Function unknown 116511281 Common - ABC-type sugar transport system, ATPase component LACR_0474 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116512497 Common - Transposase LACR_1797 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512889 Common - Diadenosine tetraphosphate (Ap4A) hydrolase related HIT family hydrolase LACR_2227 198 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 116512239 Common - Transcriptional regulator LACR_1526 138 COG2188 PhnF, Transcriptional regulators Transcription 116510956 Common rnpA ribonuclease P LACR_0129 55 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 116511169 Nonpathogen - hypothetical protein LACR_0356 1 None None None 116512641 Common - Biotin operon repressor LACR_1952 213 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 116512707 Common asnC asparaginyl-tRNA synthetase LACR_2020 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 116512107 Common - hypothetical protein LACR_1382 7 None None None 116511903 Common - Transposase LACR_1163 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511135 Common - adenosine deaminase LACR_0321 108 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 116511828 Common - Transposase LACR_1087 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511705 Nonpathogen - hypothetical protein LACR_0951 1 None None None 116510982 Nonpathogen - hypothetical protein LACR_0156 1 None None None 116511469 Common clpP ATP-dependent Clp protease proteolytic subunit LACR_0700 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116513165 Common - Aspartate racemase LACR_2531 80 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 116511007 Nonpathogen - hypothetical protein LACR_0183 1 None None None 116512242 Common - Deoxyribose-phosphate aldolase LACR_1529 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 116511843 Common - hypothetical protein LACR_1102 3 COG4707 COG4707, Uncharacterized protein conserved in bacteria Function unknown 116512604 Nonpathogen - hypothetical protein LACR_1914 1 None None None 116511193 Common - Lactoylglutathione lyase related lyase LACR_0380 42 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116511404 Common - Transcriptional regulator LACR_0630 19 COG1309 AcrR, Transcriptional regulator Transcription 116511838 Common - hypothetical protein LACR_1097 2 None None None 116512203 Nonpathogen - hypothetical protein LACR_1488 1 None None None 116512022 Common - AraC-type DNA-binding domain-containing protein LACR_1288 109 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116511037 Common - Glycosyltransferase LACR_0213 145 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116511572 Common - hypothetical protein LACR_0813 139 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 116511443 Nonpathogen - hypothetical protein LACR_0672 1 None None None 116511545 Nonpathogen - hypothetical protein LACR_0781 2 None None None 116511504 Common - Cytochrome bd-type quinol oxidase, subunit 1 LACR_0737 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 116511103 Common - Transposase LACR_0286 26 None None None 116511011 Common - hypothetical protein LACR_0187 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 116511081 Common - Predicted sugar kinase LACR_0263 206 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 116513187 Common - RecG-like helicase LACR_2553 231 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 116512697 Nonpathogen - hypothetical protein LACR_2010 1 None None None 116512174 Common - N-acetylglucosamine-6-phosphate deacetylase LACR_1458 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 116512373 Common - Transposase LACR_1670 137 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510887 Common - Glycerophosphoryl diester phosphodiesterase LACR_0053 166 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 116512125 Common - glutamate racemase LACR_1403 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 116510920 Common - SAM-dependent methyltransferase LACR_0087 10 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116511184 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component LACR_0371 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 116512918 Common - Phage terminase, small subunit LACR_2256 19 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 116511994 Nonpathogen - hypothetical protein LACR_1260 1 None None None 116511213 Common recA recombinase A LACR_0400 241 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 116513074 Common - Competence protein ComGF LACR_2422 3 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 116512875 Nonpathogen - hypothetical protein LACR_2213 1 None None None 116512900 Common recF recombination protein F LACR_2238 171 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 116511351 Common dnaG DNA primase LACR_0570 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 116512225 Nonpathogen - hypothetical protein LACR_1511 1 None None None 116511369 Common - 4-oxalocrotonate tautomerase LACR_0593 11 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 116512234 Common - Transposase LACR_1520 25 None None None 116511082 Common - Phage envelope protein LACR_0264 4 COG5562 COG5562, Phage envelope protein General function prediction only 116513027 Common - DNA-directed RNA polymerase subunit alpha LACR_2375 217 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 116511514 Common - ABC-type antimicrobial peptide transport system, ATPase component LACR_0748 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116511364 Common - enoyl-(acyl carrier protein) reductase LACR_0587 202 COG0623 FabI, Enoyl- acyl-carrier-protein 116512326 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase LACR_1622 215 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 116512298 Common - Phosphoribosylanthranilate isomerase LACR_1590 2 None None None 116512821 Nonpathogen - hypothetical protein LACR_2141 1 None None None 116511039 Common - Glycosyltransferase LACR_0215 162 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116511848 Nonpathogen - hypothetical protein LACR_1107 1 None None None 116512658 Common - NifU-like protein for Fe-S cluster formation LACR_1970 166 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 116512206 Nonpathogen - hypothetical protein LACR_1491 1 None None None 116511033 Common - ABC-type polysaccharide/polyol phosphate transport system, ATPase component LACR_0209 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 116511672 Nonpathogen - hypothetical protein LACR_0918 1 None None None 116511420 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase LACR_0647 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 116511560 Common - Nitroreductase LACR_0797 65 COG0778 NfnB, Nitroreductase Energy production and conversion 116511554 Common - hypothetical protein LACR_0791 5 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 116511440 Common - Integrase LACR_0669 217 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116512622 Common atpC F0F1 ATP synthase subunit epsilon LACR_1932 66 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 116511955 Common - Sortase (surface protein transpeptidase) LACR_1218 22 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 116511832 Common - Predicted membrane protein LACR_1091 5 COG4331 COG4331, Predicted membrane protein Function unknown 116511815 Common - riboflavin synthase subunit alpha LACR_1073 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 116512756 Common - Aminopeptidase C LACR_2073 17 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 116512344 Common - Threonine dehydrogenase related Zn-dependent dehydrogenase LACR_1641 203 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 116511839 Nonpathogen - hypothetical protein LACR_1098 2 None None None 116511823 Common - Pseudouridylate synthase, 23S RNA-specific LACR_1082 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 116511427 Common - Single-stranded DNA-specific exonuclease LACR_0656 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 116511016 Nonpathogen - hypothetical protein LACR_0192 1 None None None 116511302 Common - CTP synthetase LACR_0497 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 116512494 Nonpathogen - hypothetical protein LACR_1794 1 None None None 116511179 Common - ABC-type metal ion transport system, permease component LACR_0366 93 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 116513171 Common - NUDIX family hydrolase LACR_2537 15 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116512080 Common - Uncharacterized FAD-dependent dehydrogenase LACR_1353 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 116510943 Common - permease of the major facilitator superfamily LACR_0113 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116513196 Nonpathogen - hypothetical protein LACR_2562 1 None None None 116512252 Nonpathogen - transcription regulator LACR_1539 1 None None None 116512139 Common - hypothetical protein LACR_1418 3 None None None 116511044 Common - Polysaccharide Transporter, PST family LACR_0220 43 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116512235 Common - hypothetical protein LACR_1522 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 116511004 Common - hypothetical protein LACR_0180 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 116511265 Common - Mevalonate pyrophosphate decarboxylase LACR_0455 27 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 116511829 Common - hypothetical protein LACR_1088 8 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116511293 Nonpathogen - hypothetical protein LACR_0486 1 None None None 116511549 Common - Transcriptional regulator LACR_0786 66 COG1846 MarR, Transcriptional regulators Transcription 116511892 Common - hypothetical protein LACR_1152 2 None None None 116511093 Common - hypothetical protein LACR_0275 2 None None None 116511503 Nonpathogen - hypothetical protein LACR_0736 1 None None None 116513008 Common - Acetyltransferase, GNAT family LACR_2353 10 COG3153 COG3153, Predicted acetyltransferase General function prediction only 116511635 Nonpathogen - hypothetical protein LACR_0880 1 None None None 116511668 Common - ABC-type proline/glycine betaine transport system, permease and substrate binding protein LACR_0914 110 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 116511540 Common - Predicted transcriptional regulator containing CBS domains LACR_0776 20 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 116512356 Common - tRNA CCA-pyrophosphorylase LACR_1653 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 116513128 Common - Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta LACR_2486 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 116511920 Common rplU 50S ribosomal protein L21 LACR_1180 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 116511702 Nonpathogen - hypothetical protein LACR_0948 3 None None None 116512933 Nonpathogen - hypothetical protein LACR_2271 1 None None None 116511347 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase LACR_0548 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 116513217 Nonpathogen - hypothetical protein LACR_2593 2 None None None 116512522 Common - uridine kinase LACR_1825 84 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 116510983 Common - Transcriptional regulator, xre family LACR_0157 3 None None None 116511687 Common - Predicted membrane protein LACR_0933 5 COG3152 COG3152, Predicted membrane protein Function unknown 116512167 Common - SAM-dependent methyltransferase LACR_1451 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116512216 Common - hypothetical protein LACR_1502 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 116513157 Nonpathogen - hypothetical protein LACR_2522 1 None None None 116512142 Nonpathogen - hypothetical protein LACR_1421 1 None None None 116511575 Common - hypothetical protein LACR_0816 13 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 116512645 Common - Acetyl-CoA acetyltransferase LACR_1956 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 116512804 Nonpathogen - hypothetical protein LACR_2123 1 None None None 116512861 Nonpathogen - hypothetical protein LACR_2197 1 None None None 116512114 Common - Predicted transcriptional regulator LACR_1390 17 COG2932 COG2932, Predicted transcriptional regulator Transcription 116511055 Common - Nicotinic acid mononucleotide adenylyltransferase LACR_0231 149 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 116511717 Common - Predicted membrane protein LACR_0965 6 COG4758 COG4758, Predicted membrane protein Function unknown 116512709 Common - aspartate aminotransferase LACR_2022 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116512635 Common - ABC-type uncharacterized transport system, ATPase component LACR_1946 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 116511155 Common - permease of the major facilitator superfamily LACR_0342 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511327 Common - hypothetical protein LACR_0524 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 116512944 Nonpathogen - hypothetical protein LACR_2282 1 None None None 116511102 Nonpathogen - hypothetical protein LACR_0285 1 None None None 116512859 Common - Pentose-5-phosphate-3-epimerase LACR_2195 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 116511871 Nonpathogen - hypothetical protein LACR_1130 1 None None None 116511980 Common tpiA triosephosphate isomerase LACR_1244 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 116513181 Common trmE tRNA modification GTPase TrmE LACR_2547 216 COG0486 ThdF, Predicted GTPase General function prediction only 116511624 Common - Predicted multitransmembrane protein LACR_0867 17 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 116512984 Common - Arginine repressor LACR_2324 55 COG1438 ArgR, Arginine repressor Transcription 116513137 Common rpsR 30S ribosomal protein S18 LACR_2501 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 116512159 Common - ATPase for DNA repair LACR_1443 155 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 116512070 Common - Exoribonuclease R LACR_1342 192 COG0557 VacB, Exoribonuclease R Transcription 116511278 Common celA 6-phospho-beta-glucosidase LACR_0469 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116511286 Common - Phosphomannomutase LACR_0479 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 116512268 Nonpathogen - hypothetical protein LACR_1556 1 None None None 116511197 Common - Alkyl hydroperoxide reductase, large subunit LACR_0384 247 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 116511070 Common - Ribosomal protein S21 LACR_0246 101 None None None 116511260 Nonpathogen - hypothetical protein LACR_0450 1 None None None 116511254 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_0444 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116512021 Common - Spermidine/putrescine-binding periplasmic protein LACR_1287 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116513146 Nonpathogen - hypothetical protein LACR_2510 1 None None None 116511989 Common - Predicted membrane protein LACR_1255 9 COG4478 COG4478, Predicted membrane protein Function unknown 116511934 Common glyQ glycyl-tRNA synthetase subunit alpha LACR_1196 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 116513188 Common - Uncharacterized Zn-ribbon-containing protein (phosphonate metabolism) LACR_2554 84 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 116511801 Common - ATPase for in cell division LACR_1058 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 116511932 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase LACR_1194 79 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 116511136 Nonpathogen - hypothetical protein LACR_0322 3 None None None 116512763 Common - pyrroline-5-carboxylate reductase LACR_2080 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 116511313 Nonpathogen - hypothetical protein LACR_0508 1 None None None 116511110 Common - Metal-dependent amidase/aminoacylase/carboxypeptidase LACR_0294 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 116512310 Common - permease of the major facilitator superfamily LACR_1603 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511191 Common - Aldo/keto reductase of diketogulonate reductase family LACR_0378 152 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 116512776 Nonpathogen - hypothetical protein LACR_2095 2 None None None 116512077 Common - TPR repeat containing protein LACR_1350 54 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 116512997 Common - Predicted flavin-nucleotide-binding protein LACR_2339 39 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 116512363 Common - Lysophospholipase LACR_1660 93 COG2267 PldB, Lysophospholipase Lipid metabolism 116512924 Nonpathogen - hypothetical protein LACR_2262 1 None None None 116512018 Common - ABC-type spermidine/putrescine transport system, ATPase component LACR_1284 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116511861 Nonpathogen - hypothetical protein LACR_1120 1 None None None 116512505 Nonpathogen - hypothetical protein LACR_1807 1 None None None 116511497 Common - Transcriptional regulator, xre family LACR_0730 17 COG1476 COG1476, Predicted transcriptional regulators Transcription 116511760 Common - Amidase LACR_1016 76 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116513066 Common - Pseudouridylate synthase, 23S RNA-specific LACR_2414 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 116512828 Common - hypothetical protein LACR_2148 5 None None None 116513110 Common - permease of the major facilitator superfamily LACR_2466 42 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512597 Common - 3-phosphoshikimate 1-carboxyvinyltransferase LACR_1907 234 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 116511680 Common - Geranylgeranyl pyrophosphate synthase LACR_0926 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 116511784 Nonpathogen - hypothetical protein LACR_1040 1 None None None 116513094 Common - DNA polymerase I LACR_2445 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 116511340 Common - Transposase LACR_0541 49 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510988 Common - DNA-entry nuclease LACR_0163 4 None None None 116512553 Common - Cytidylate kinase LACR_1860 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 116511878 Nonpathogen - hypothetical protein LACR_1138 1 None None None 116512169 Common - ABC-type uncharacterized transport system, permease component LACR_1453 108 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 116512121 Common xerD site-specific tyrosine recombinase XerD-like protein LACR_1399 4 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116512576 Common - Predicted transcriptional regulator LACR_1884 137 COG1733 COG1733, Predicted transcriptional regulators Transcription 116511460 Common - Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase LACR_0689 180 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 116511020 Common - Dihydroxyacetone kinase related enzyme LACR_0196 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 116512134 Common - Transcriptional regulator, xre family LACR_1413 5 None None None 116512957 Common - Acetate kinase LACR_2295 161 COG0282 ackA, Acetate kinase Energy production and conversion 116512437 Common ulaA ascorbate-specific PTS system enzyme IIC LACR_1735 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 116512906 Common - galactokinase LACR_2244 84 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 116511100 Common eno phosphopyruvate hydratase LACR_0283 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 116511162 Common - hypothetical protein LACR_0349 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 116512682 Common - Transposase LACR_1994 33 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511109 Common - Galactoside O-acetyltransferase LACR_0293 120 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 116512692 Nonpathogen - Cell wall-associated hydrolase LACR_2005 2 None None None 116511453 Common - hypothetical protein LACR_0682 3 None None None 116511271 Common - Superfamily II DNA and RNA helicase LACR_0462 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 116512023 Common - permease of the major facilitator superfamily LACR_1289 33 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511611 Common - Transposase LACR_0854 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512335 Common thyA thymidylate synthase LACR_1631 134 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 116512272 Common - Anthranilate/para-aminobenzoate synthase component I LACR_1560 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 116512812 Common - hypothetical protein LACR_2132 5 None None None 116510981 Common - hypothetical protein LACR_0155 8 None None None 116513084 Common - Undecaprenyl pyrophosphate synthase LACR_2435 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 116512405 Common - Ribosomal protein L31 LACR_1703 141 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 116512868 Common - Possible chitinase (chitin-binding domain type 3) LACR_2205 26 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 116511607 Common - Transposase LACR_0849 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512960 Common - Predicted membrane GTPase for stress response LACR_2298 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 116513190 Common - hypothetical protein LACR_2556 3 None None None 116512987 Nonpathogen - hypothetical protein LACR_2327 1 None None None 116513071 Common - ABC-type metal ion transport system, periplasmic component/surface adhesin LACR_2419 181 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 116511309 Nonpathogen - hypothetical protein LACR_0504 1 None None None 116511653 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_0898 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116511904 Nonpathogen - hypothetical protein LACR_1164 1 None None None 116512402 Common - Signal transduction histidine kinase LACR_1700 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116512300 Common - Transposase LACR_1592 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512188 Common - Transcriptional regulator LACR_1472 124 COG2188 PhnF, Transcriptional regulators Transcription 116511757 Common - Thioredoxin reductase LACR_1013 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 116510863 Common - Transcriptional antiterminator LACR_0028 13 COG3711 BglG, Transcriptional antiterminator Transcription 116511744 Common - Glycosyl/glycerophosphate transferase LACR_0998 35 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 116512814 Nonpathogen - hypothetical protein LACR_2134 1 None None None 116510999 Common - Cold shock protein LACR_0174 183 COG1278 CspC, Cold shock proteins Transcription 116511868 Nonpathogen - hypothetical protein LACR_1127 1 None None None 116512671 Common - Transcriptional regulator, xre family LACR_1983 4 None None None 116512561 Common - hypothetical protein LACR_1869 9 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 116512568 Common - Phosphate uptake regulator LACR_1876 191 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 116512475 Nonpathogen - hypothetical protein LACR_1775 1 None None None 116511318 Common - Predicted Rossmann fold nucleotide-binding protein LACR_0514 146 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 116513104 Nonpathogen - hypothetical protein LACR_2459 2 None None None 116512451 Nonpathogen - hypothetical protein LACR_1749 2 None None None 116512072 Common - Transcriptional regulator, xre family LACR_1344 6 None None None 116512031 Common - Saccharopine dehydrogenase related protein LACR_1297 38 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116512581 Common - Predicted O-methyltransferase LACR_1889 123 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 116511089 Nonpathogen - hypothetical protein LACR_0271 2 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 116512647 Nonpathogen - hypothetical protein LACR_1958 1 None None None 116513040 Nonpathogen - hypothetical protein LACR_2388 1 None None None 116512425 Common - Transposase LACR_1723 28 None None None 116511018 Common - Fe2+ transport system protein A LACR_0194 56 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 116512678 Common - alcohol dehydrogenase LACR_1990 217 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 116510958 Common - Predicted RNA-binding protein LACR_0131 27 COG1847 Jag, Predicted RNA-binding protein General function prediction only 116512974 Common - Transposase LACR_2313 27 None None None 116511233 Common - Enzyme with possible activities of L-2-hydroxyisocaproate/malate/lactate dehydrogenase LACR_0421 169 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 116513144 Common - GAF domain-containing protein protein LACR_2508 85 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 116512279 Common - Predicted transcriptional regulator LACR_1570 81 COG0789 SoxR, Predicted transcriptional regulators Transcription 116510875 Common - Acetyltransferase, GNAT family LACR_0040 44 COG0456 RimI, Acetyltransferases General function prediction only 116511425 Common - ribonuclease Z LACR_0654 127 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 116511232 Nonpathogen - hypothetical protein LACR_0420 1 None None None 116511822 Common - Lipoprotein signal peptidase LACR_1081 179 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116512458 Common - hypothetical protein LACR_1757 3 None None None 116512048 Nonpathogen - hypothetical protein LACR_1318 1 None None None 116512517 Nonpathogen - hypothetical protein LACR_1820 1 None None None 116512795 Nonpathogen - hypothetical protein LACR_2114 1 None None None 116512246 Common - pantothenate kinase LACR_1533 99 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 116512899 Common - S4-like RNA-binding protein LACR_2237 30 COG2501 COG2501, Uncharacterized conserved protein Function unknown 116512793 Common - hypothetical protein LACR_2112 2 None None None 116512053 Common - Isopropylmalate synthase LACR_1323 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 116513224 Common - Putative glucose uptake permease LACR_2601 11 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 116511068 Common - permease of the major facilitator superfamily LACR_0244 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512848 Common - ATP-cone domain LACR_2182 3 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 116510904 Common - Universal stress protein UspA related nucleotide-binding protein LACR_0071 128 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116512348 Common - Peptide methionine sulfoxide reductase LACR_1645 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 116512481 Nonpathogen - hypothetical protein LACR_1781 1 None None None 116511283 Common - Transposase LACR_0476 27 None None None 116512079 Common - SAM-dependent methyltransferase LACR_1352 165 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116511563 Common - Transcriptional regulator, xre family LACR_0800 4 None None None 116511707 Nonpathogen - hypothetical protein LACR_0953 1 None None None 116510891 Common - tryptophanyl-tRNA synthetase II LACR_0058 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511438 Common - Ribosome-associated protein Y (PSrp-1) LACR_0667 174 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 116510845 Common - DNA polymerase III subunit beta LACR_0002 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 116511521 Common - Cold shock protein LACR_0756 182 COG1278 CspC, Cold shock proteins Transcription 116512550 Common - Transposase LACR_1857 28 None None None 116512390 Common - cell surface protein LACR_1688 7 None None None 116511947 Common - Alpha-acetolactate decarboxylase LACR_1209 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 116510936 Nonpathogen - hypothetical protein LACR_0105 1 None None None 116512836 Common - DNA-directed RNA polymerase subunit omega LACR_2157 17 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 116511147 Common - hypothetical protein LACR_0333 3 None None None 116511770 Common - Molecular chaperone GrpE (heat shock protein) LACR_1026 220 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 116512097 Common - Cation transport ATPase LACR_1370 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116511046 Common - Predicted membrane protein LACR_0222 5 COG4713 COG4713, Predicted membrane protein Function unknown 116512351 Common - ABC transporter ATPase, two domains LACR_1648 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116511772 Common - hypothetical protein LACR_1028 5 COG5617 COG5617, Predicted integral membrane protein Function unknown 116512841 Common - Cyclopropane fatty acid synthase related methyltransferase LACR_2162 140 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 116511449 Nonpathogen - hypothetical protein LACR_0678 1 None None None 116513011 Common - Predicted transcriptional regulator LACR_2356 51 COG1695 COG1695, Predicted transcriptional regulators Transcription 116510951 Common - Transposase LACR_0122 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512524 Common - Transglycosylase-like domain LACR_1828 5 None None None 116511399 Nonpathogen - hypothetical protein LACR_0625 1 None None None 116511894 Nonpathogen - hypothetical protein LACR_1154 2 None None None 116512720 Common - Translation initiation factor 3 (IF-3) LACR_2033 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 116512730 Nonpathogen - Predicted integral membrane protein LACR_2044 1 COG3548 COG3548, Predicted integral membrane protein Function unknown 116512090 Common - Arsenate reductase related protein, glutaredoxin family LACR_1363 16 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116511882 Common - hypothetical protein LACR_1142 4 None None None 116513216 Common - hypothetical protein LACR_2592 2 None None None 116513204 Common - Plasmid replication protein Rep and AAA-class ATPase domain LACR_2580 5 None None None 116511889 Common - hypothetical protein LACR_1149 3 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116510935 Common - Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) LACR_0104 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 116511223 Common - Pseudouridylate synthase, 23S RNA-specific LACR_0410 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 116511974 Common - bifunctional riboflavin kinase/FMN adenylyltransferase LACR_1238 211 COG0196 RibF, FAD synthase Coenzyme metabolism 116512001 Nonpathogen - hypothetical protein LACR_1267 1 None None None 116512358 Common - dihydrodipicolinate reductase LACR_1655 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 116512086 Common - Cation transport ATPase LACR_1359 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116511945 Common - Predicted glutamine amidotransferase LACR_1207 51 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 116511858 Nonpathogen - hypothetical protein LACR_1117 1 None None None 116511115 Common - Integrase LACR_0301 176 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116513033 Common secY preprotein translocase subunit SecY LACR_2381 247 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 116513014 Common - Predicted membrane protein LACR_2359 15 COG3619 COG3619, Predicted membrane protein Function unknown 116512542 Common - alpha-amylase LACR_1849 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116511641 Common - NADH dehydrogenase, FAD-containing subunit LACR_0886 169 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 116511330 Common - ABC-type multidrug transport system, ATPase component LACR_0530 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116512668 Common - DNA-directed RNA polymerase subunit beta' LACR_1980 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 116511127 Nonpathogen - hypothetical protein LACR_0313 1 None None None 116511533 Common - L-alanine-DL-glutamate epimerase related enzyme of enolase superfamily LACR_0769 122 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116511029 Common - dTDP-4-dehydrorhamnose reductase LACR_0205 187 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 116512538 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_1845 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116512386 Nonpathogen - hypothetical protein LACR_1684 1 None None None 116511392 Common - Soluble lytic murein transglycosylase related regulatory protein LACR_0618 8 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 116512291 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein LACR_1583 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 116513022 Common - Glycosyltransferase, family 11 LACR_2369 9 None None None 116512399 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase LACR_1697 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 116512661 Common - ABC-type transport system for Fe-S cluster assembly, permease component LACR_1973 183 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 116511814 Common - Mg2+ and Co2+ transporter LACR_1071 26 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 116512435 Nonpathogen - hypothetical protein LACR_1733 1 None None None 116511913 Common - Predicted SAM-dependent methyltransferase LACR_1173 32 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 116511779 Common - Transposase LACR_1035 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512696 Common - Excinuclease ATPase subunit LACR_2009 233 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 116511569 Nonpathogen - hypothetical protein LACR_0809 1 None None None 116512416 Common - Predicted transcriptional regulator LACR_1714 15 COG0640 ArsR, Predicted transcriptional regulators Transcription 116511049 Common - inositol-5-monophosphate dehydrogenase LACR_0225 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 116511698 Common - RelA / SpoT (ppGpp synthetase/hydrolase) catalytic domain LACR_0944 53 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 116511580 Common - 3-oxoacyl-(acyl carrier protein) synthase III LACR_0821 217 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 116512786 Common - Predicted ribosomal protein LACR_2105 14 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 116510974 Common - Transcriptional regulator LACR_0148 49 COG1309 AcrR, Transcriptional regulator Transcription 116511733 Common gyrB DNA gyrase subunit B LACR_0984 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 116512427 Common - Signal recognition particle GTPase LACR_1725 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 116511300 Common - hypothetical protein LACR_0494 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 116513176 Nonpathogen - hypothetical protein LACR_2542 1 None None None 116510873 Common - Transposase LACR_0038 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512853 Common - Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities LACR_2187 232 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 116511001 Common - hypothetical protein LACR_0177 5 None None None 116511793 Common - Transcriptional regulator LACR_1050 5 COG1309 AcrR, Transcriptional regulator Transcription 116511841 Nonpathogen - hypothetical protein LACR_1100 1 None None None 116512277 Common - Fe2+/Zn2+ uptake regulation protein LACR_1568 125 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 116511091 Common - Amidase LACR_0273 42 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116512211 Common - hypothetical protein LACR_1496 14 None None None 116511817 Common - Riboflavin synthase beta-chain LACR_1075 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 116512270 Common trpD anthranilate phosphoribosyltransferase LACR_1558 223 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 116510879 Common - Predicted acetyltransferase LACR_0044 88 COG3153 COG3153, Predicted acetyltransferase General function prediction only 116512260 Common trpA tryptophan synthase subunit alpha LACR_1548 215 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 116512006 Common clpX ATP-dependent protease ATP-binding subunit LACR_1272 229 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 116511684 Common - ATPase for DNA repair LACR_0930 207 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 116511447 Common - hypothetical protein LACR_0676 2 None None None 116511084 Common - ABC-type multidrug transport system, ATPase and permease component LACR_0266 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116513115 Common - Predicted Fe-S-cluster oxidoreductase LACR_2472 11 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 116511780 Common - Transposase LACR_1036 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512254 Common - ABC-type proline/glycine betaine transport system, permease component LACR_1541 155 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 116511380 Common - hypothetical protein LACR_0606 2 None None None 116512220 Common - Predicted integral membrane protein LACR_1506 29 COG3548 COG3548, Predicted integral membrane protein Function unknown 116512788 Nonpathogen - hypothetical protein LACR_2107 1 None None None 116513150 Common - Protein-tyrosine-phosphatase LACR_2514 128 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 116512227 Common - Acetyltransferase, including N-acetylase of ribosomal protein LACR_1513 53 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116511014 Common - Geranylgeranyl pyrophosphate synthase LACR_0190 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 116511666 Common - Glutathione reductase LACR_0912 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 116511128 Nonpathogen - hypothetical protein LACR_0314 1 None None None 116511042 Common - hypothetical protein LACR_0218 9 None None None 116511960 Common - 3-methyladenine DNA glycosylase LACR_1224 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 116511506 Common - ABC-type transport system for cytochrome bd biosynthesis, ATPase and permease component LACR_0739 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 116512588 Common - hypothetical protein LACR_1898 50 COG1556 COG1556, Uncharacterized conserved protein Function unknown 116511394 Common - Phosphoglycerate dehydrogenase LACR_0620 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 116513126 Common - hypothetical protein LACR_2484 34 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 116511996 Nonpathogen - hypothetical protein LACR_1262 1 None None None 116510944 Common - Transposase LACR_0114 34 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511626 Nonpathogen - hypothetical protein LACR_0869 1 None None None 116510884 Common - acetoin dehydrogenase complex, E1 component, beta subunit LACR_0050 209 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 116511516 Common - Predicted membrane protein LACR_0750 16 COG3619 COG3619, Predicted membrane protein Function unknown 116511854 Nonpathogen - hypothetical protein LACR_1113 1 None None None 116512177 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase LACR_1461 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 116511121 Nonpathogen - hypothetical protein LACR_0307 1 None None None 116511725 Common - acetoin reductase LACR_0974 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116513044 Common - Ribosomal protein L14 LACR_2392 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 116511026 Common - dTDP-4-dehydrorhamnose 3,5-epimerase related enzyme LACR_0202 152 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 116512329 Common - Gamma-carboxymuconolactone decarboxylase subunit-like protein LACR_1625 68 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 116510922 Common prmA ribosomal protein L11 methyltransferase LACR_0089 177 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 116512902 Common - Predicted transcriptional regulator LACR_2240 134 COG0789 SoxR, Predicted transcriptional regulators Transcription 116510889 Nonpathogen - hypothetical protein LACR_0056 1 None None None 116511186 Common - ABC-type Fe3+-siderophore transport system, permease component LACR_0373 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 116511455 Common - Transposase LACR_0684 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511362 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain LACR_0584 170 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116512296 Nonpathogen - hypothetical protein LACR_1588 1 None None None 116511220 Common - Uncharacterized integral membrane protein LACR_0407 24 COG3739 COG3739, Uncharacterized integral membrane protein Function unknown 116513016 Common - DNA repair protein RadA LACR_2361 211 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 116512137 Common rbgA ribosomal biogenesis GTPase LACR_1416 156 COG1161 COG1161, Predicted GTPases General function prediction only 116512112 Nonpathogen - hypothetical protein LACR_1388 1 None None None 116511113 Nonpathogen - hypothetical protein LACR_0299 2 None None None 116511332 Common - Response regulator of the LytR/AlgR family LACR_0532 10 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 116511131 Nonpathogen - hypothetical protein LACR_0317 1 None None None 116511400 Common - Predicted transcriptional regulator LACR_0626 138 COG0789 SoxR, Predicted transcriptional regulators Transcription 116512633 Common - DNA uptake protein related DNA-binding protein LACR_1944 107 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 116511353 Common - glycerol-3-phosphatase transporter LACR_0573 111 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 116511274 Common - cellobiose-specific PTS system IIB component LACR_0465 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 116512643 Common - Transposase LACR_1954 26 None None None 116512946 Common rplK 50S ribosomal protein L11 LACR_2284 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 116511670 Nonpathogen - hypothetical protein LACR_0916 1 None None None 116512907 Common - aldose 1-epimerase LACR_2245 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 116511407 Common - Conserved membrane protein, GtcA family LACR_0633 3 COG2246 COG2246, Predicted membrane protein Function unknown 116511834 Common - Membrane-associated phospholipid phosphatase LACR_1093 59 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 116512656 Common - hypothetical protein LACR_1968 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 116511957 Nonpathogen - hypothetical protein LACR_1220 1 None None None 116511215 Common - Gamma-aminobutyrate permease related permease LACR_0402 123 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 116510971 Common - Transcriptional regulator LACR_0144 25 COG1309 AcrR, Transcriptional regulator Transcription 116512754 Common - permease of the major facilitator superfamily LACR_2069 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512548 Common - ABC-type maltose transport system, permease component LACR_1855 153 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 116511987 Common - Acyl-ACP thioesterase LACR_1253 22 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 116510848 Common - hypothetical protein LACR_0005 27 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 116512492 Nonpathogen - hypothetical protein LACR_1792 1 None None None 116511138 Common - mRNA degradation ribonuclease J1/J2, metallo-beta-lactamase superfamily enzyme LACR_0324 157 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 116511930 Common - hypothetical protein LACR_1191 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 116511990 Common - guanosine 5'-monophosphate oxidoreductase LACR_1256 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 116512909 Common - Transcriptional regulator LACR_2247 71 COG1737 RpiR, Transcriptional regulators Transcription 116512694 Common - Transposase LACR_2007 27 None None None 116513140 Common - undecaprenyl pyrophosphate phosphatase LACR_2504 196 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 116512324 Common - Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain LACR_1620 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 116511863 Common - dUTPase LACR_1122 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 116512104 Common - hydroxyethylthiazole kinase LACR_1377 78 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 116511722 Common - Predicted RNA binding protein (contains ribosomal protein S1 domain) LACR_0970 134 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 116513064 Common - hypothetical protein, LysM motif LACR_2412 6 None None None 116511295 Common - Acetyltransferase, GNAT family LACR_0488 51 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116512995 Common - Transposase LACR_2337 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512461 Common - hypothetical protein LACR_1761 186 COG4926 PblB, Phage-related protein Function unknown 116510856 Common - Septum formation initiator LACR_0013 3 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 116511719 Common - DNA-binding response regulator (Rec-wHTH domains) LACR_0967 213 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116511267 Common - isopentenyl pyrophosphate isomerase LACR_0457 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 116511495 Common - Transposase LACR_0728 26 None None None 116511709 Common - nucleoid DNA-binding protein LACR_0955 178 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 116512926 Nonpathogen - Transcriptional regulator, xre family LACR_2264 1 None None None 116512781 Nonpathogen - hypothetical protein LACR_2100 2 None None None 116512888 Common aspS aspartyl-tRNA synthetase LACR_2226 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116513226 Common - Radical SAM superfamily enzyme LACR_2603 83 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 116512599 Common - Signal transduction histidine kinase LACR_1909 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116512430 Common - Putative Mg2+ Transporter-C (MgtC) Family LACR_1728 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 116510962 Nonpathogen - hypothetical protein LACR_0135 1 None None None 116513149 Common - glutamine synthetase repressor LACR_2513 12 COG0789 SoxR, Predicted transcriptional regulators Transcription 116512248 Common - Predicted Co/Zn/Cd cation transporter LACR_1535 53 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 116512266 Nonpathogen - hypothetical protein LACR_1554 1 None None None 116512710 Common - hypothetical protein LACR_2023 4 COG5353 COG5353, Uncharacterized protein conserved in bacteria Function unknown 116511685 Nonpathogen - hypothetical protein LACR_0931 1 None None None 116513206 Common - Integrase LACR_2582 76 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116512160 Common - DNA repair exonuclease LACR_1444 123 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 116511251 Common - Metal-dependent hydrolase of the beta-lactamase superfamily I LACR_0441 59 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 116513210 Common - ABC-type antimicrobial peptide transport system, ATPase component LACR_2586 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116511194 Nonpathogen - hypothetical protein LACR_0381 1 None None None 116511371 Common - Acetyltransferase, GNAT family LACR_0595 46 COG0456 RimI, Acetyltransferases General function prediction only 116513135 Common - hypothetical protein LACR_2499 4 None None None 116513112 Common - hypothetical protein LACR_2469 5 None None None 116513219 Common - 30S ribosomal protein S7 LACR_2596 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 116511446 Common - Transposase LACR_0675 26 None None None 116511511 Common - Lysophospholipase L1 related esterase LACR_0744 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116510909 Common rpmG 50S ribosomal protein L33 LACR_0076 78 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 116513200 Nonpathogen - hypothetical protein LACR_2576 1 None None None 116511367 Common - Predicted membrane protein LACR_0590 10 COG4684 COG4684, Predicted membrane protein Function unknown 116511189 Common - Transposase LACR_0376 27 None None None 116512150 Common - Endoglucanase Y LACR_1432 9 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 116511288 Common - Phosphotransferase system IIA component LACR_0481 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 116512198 Common - Beta-propeller domains of methanol dehydrogenase type LACR_1483 4 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 116512208 Common - Transposase LACR_1493 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511235 Common - Transposase LACR_0423 25 None None None 116513199 Common - hypothetical protein LACR_2575 3 None None None 116511329 Common - Acetyltransferase, GNAT family LACR_0526 53 COG0456 RimI, Acetyltransferases General function prediction only 116511057 Common - Acetyltransferase, GNAT family LACR_0233 27 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116511601 Nonpathogen - hypothetical protein LACR_0843 1 None None None 116511769 Common hrcA heat-inducible transcription repressor LACR_1025 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 116511431 Common - Transcription elongation factor LACR_0660 204 COG0782 GreA, Transcription elongation factor Transcription 116511258 Common - DNA replication intiation control protein YabA LACR_0448 10 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 116512346 Common - Predicted membrane protein LACR_1643 12 COG4905 COG4905, Predicted membrane protein Function unknown 116512878 Nonpathogen - hypothetical protein LACR_2216 1 None None None 116510900 Nonpathogen - hypothetical protein LACR_0067 1 None None None 116511552 Common - Ribosomal protein L9 LACR_0789 193 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 116512882 Nonpathogen - hypothetical protein LACR_2220 1 None None None 116512719 Common rpmI 50S ribosomal protein L35 LACR_2032 123 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 116513001 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain LACR_2344 77 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116512038 Common - Putative translation initiation inhibitor, yjgF family LACR_1306 180 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116512816 Nonpathogen - hypothetical protein LACR_2136 1 None None None 116512033 Common - hypothetical protein LACR_1301 3 None None None 116512044 Common - ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA LACR_1313 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 116512791 Common - Phage terminase, small subunit LACR_2110 21 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 116510916 Common - Acetyltransferase, GNAT family LACR_0083 80 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116511636 Common - Transposase LACR_0881 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510993 Common - transcriptional repressor CodY LACR_0168 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 116511079 Common - Predicted SAM-dependent methyltransferase LACR_0259 127 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 116510990 Nonpathogen - hypothetical protein LACR_0165 1 None None None 116512028 Common - hypothetical protein LACR_1294 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 116512432 Common - ADP-ribose pyrophosphatase LACR_1730 19 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116511742 Common - Lipopolysaccharide biosynthesis glycosyltransferase LACR_0995 17 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 116511676 Common xseA exodeoxyribonuclease VII large subunit LACR_0922 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 116512743 Common - Cell division protein, S4-like domain LACR_2058 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 116512477 Common - Phage portal protein, SPP1 Gp6-like LACR_1777 9 None None None 116511631 Common leuS leucyl-tRNA synthetase LACR_0875 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511663 Common - Phosphopantetheinyl transferase (holo-ACP synthase) LACR_0909 154 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 116511501 Common - Dipeptide/tripeptide permease LACR_0734 83 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 116512423 Common - Predicted branched-chain amino acid permease (azaleucine resistance) LACR_1721 109 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 116512529 Nonpathogen - hypothetical protein LACR_1833 1 None None None 116511513 Common - Uncharacterized membrane-associated protein LACR_0747 156 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 116511523 Common - Diadenosine tetraphosphatase related serine/threonine protein phosphatase LACR_0758 4 None None None 116511173 Common - ABC-type metal ion transport system, periplasmic component/surface antigen LACR_0360 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 116512384 Common - cell surface protein LACR_1682 8 None None None 116512051 Common - Predicted membrane protein LACR_1321 3 COG3152 COG3152, Predicted membrane protein Function unknown 116512798 Nonpathogen - hypothetical protein LACR_2117 1 None None None 116512046 Common - hypothetical protein LACR_1316 2 None None None 116513025 Common - Peptidoglycan interpeptide bridge formation enzyme LACR_2372 17 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 116512912 Common - Phosphoglycerate dehydrogenase related enzyme LACR_2250 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 116511482 Common - hypothetical protein LACR_0714 17 COG3592 COG3592, Uncharacterized conserved protein Function unknown 116512519 Common - Predicted hydrolase of the HAD superfamily LACR_1822 106 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116511777 Common - Fusion of IIA, IIB and IIC component of mannitol/fructose-specific phosphotransferase system mannitol/fructose-specific LACR_1033 142 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 116512972 Common - DNA-binding ferritin-like protein (oxidative damage protectant) LACR_2311 89 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 116511243 Common - glutamyl aminopeptidase LACR_0433 81 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 116511949 Common - Predicted nucleoside-diphosphate-sugar epimerase LACR_1211 91 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 116511618 Nonpathogen - hypothetical protein LACR_0861 1 None None None 116512411 Common - carbamoyl phosphate synthase small subunit LACR_1709 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 116512439 Common - Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) LACR_1737 48 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 116512966 Nonpathogen - hypothetical protein LACR_2304 1 None None None 116512690 Common - Predicted transcriptional regulator LACR_2002 28 COG1959 COG1959, Predicted transcriptional regulator Transcription 116511755 Common - ABC-type polar amino acid transport system, ATPase component LACR_1011 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116511577 Common - Ribosome-binding factor A LACR_0818 129 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 116512572 Common - ABC-type phosphate transport system, permease component LACR_1880 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 116512132 Common - Small-conductance mechanosensitive channel LACR_1410 52 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116511565 Nonpathogen - hypothetical protein LACR_0803 1 None None None 116512555 Common - Ferredoxin LACR_1862 5 COG1141 Fer, Ferredoxin Energy production and conversion 116513058 Common nusG transcription antitermination protein NusG LACR_2406 215 COG0250 NusG, Transcription antiterminator Transcription 116511922 Common rpmA 50S ribosomal protein L27 LACR_1182 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 116511462 Common - Pyruvate-formate lyase LACR_0691 53 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 116511643 Common - L-serine deaminase LACR_0888 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 116512403 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_1701 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116511379 Common - hypothetical protein LACR_0605 3 None None None 116512531 Common - Transcriptional regulator, xre family LACR_1835 5 None None None 116512256 Common - Regulatory, ligand-binding protein; C-terminal domains of K+ channels-related LACR_1543 30 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 116510986 Common - permease of the major facilitator superfamily LACR_0161 73 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116510860 Common - Hypoxanthine-guanine phosphoribosyltransferase LACR_0017 153 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 116510858 Common - Beta-lactamase class A LACR_0015 10 COG2367 PenP, Beta-lactamase class A Defense mechanisms 116512919 Nonpathogen - hypothetical protein LACR_2257 1 None None None 116512186 Common - 2-polyprenylphenol hydroxylase related flavodoxin oxidoreductase LACR_1470 88 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 116511412 Common - prolipoprotein diacylglyceryl transferase LACR_0639 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 116512566 Common - Microcin C7 resistance-like protein (MccF) LACR_1874 81 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 116510865 Common - mannitol-1-phosphate 5-dehydrogenase LACR_0030 84 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 116512100 Common - D-alanyl transfer protein LACR_1373 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 116511311 Nonpathogen - hypothetical protein LACR_0506 1 None None None 116511976 Common - hypothetical protein LACR_1240 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 116512810 Nonpathogen - hypothetical protein LACR_2130 1 None None None 116512025 Common - Beta-xylosidase LACR_1291 41 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 116511107 Common - Thiol-disulfide isomerase and thioredoxin LACR_0291 3 None None None 116512463 Common - Minor tail protein gp26-like protein LACR_1763 23 COG5412 COG5412, Phage-related protein Function unknown 116510953 Common - Argininosuccinate lyase LACR_0126 233 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 116512676 Nonpathogen - hypothetical protein LACR_1988 1 None None None 116511063 Common - uracil-DNA glycosylase LACR_0239 130 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 116513035 Common rpmD 50S ribosomal protein L30 LACR_2383 136 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 116511535 Common - naphthoate synthase LACR_0771 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 116511316 Common - Predicted membrane protein LACR_0511 44 COG4420 COG4420, Predicted membrane protein Function unknown 116511342 Common recU Holliday junction-specific endonuclease LACR_0543 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 116511458 Common - ABC-type antimicrobial peptide transport system, permease component LACR_0687 19 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116512770 Common - hypothetical protein LACR_2087 8 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116511782 Common - Predicted membrane protein LACR_1038 11 COG3152 COG3152, Predicted membrane protein Function unknown 116511731 Common - Predicted ring-cleavage extradiol dioxygenase LACR_0982 37 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 116512088 Common - Aldo/keto reductase of diketogulonate reductase family LACR_1361 186 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 116512736 Common - Universal stress protein UspA related nucleotide-binding protein LACR_2050 138 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116512764 Common rpsO 30S ribosomal protein S15 LACR_2081 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 116513031 Common infA translation initiation factor IF-1 LACR_2379 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 116512667 Common - Diacylglycerol kinase family protein LACR_1979 81 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 116511856 Nonpathogen - hypothetical protein LACR_1115 1 None None None 116512418 Common proA gamma-glutamyl phosphate reductase LACR_1716 205 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 116511795 Common - Putative exporter of polyketide antibiotics LACR_1052 18 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 116512213 Common carB carbamoyl phosphate synthase large subunit LACR_1498 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 116512801 Common - hypothetical protein LACR_2120 3 None None None 116510910 Common rpmF 50S ribosomal protein L32 LACR_0077 51 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 116511911 Common - Putative primosome component related protein LACR_1171 19 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 116511918 Common - hypothetical protein LACR_1178 2 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 116512371 Common - hydrolase of the alpha/beta superfamily LACR_1668 72 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 116512293 Common - Transcriptional regulator/sugar kinase LACR_1585 139 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116512337 Common - Transposase LACR_1634 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513118 Common - Predicted nucleoside-diphosphate-sugar epimerase LACR_2475 71 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116513207 Common rpsI 30S ribosomal protein S9 LACR_2583 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 116511387 Common - Nitroreductase LACR_0613 62 COG0778 NfnB, Nitroreductase Energy production and conversion 116513020 Common - Phosphoheptose isomerase LACR_2365 130 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 116511402 Common - flavodoxin LACR_0628 93 COG0716 FldA, Flavodoxins Energy production and conversion 116512317 Common - phosphoribosylaminoimidazole synthetase LACR_1611 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 116512613 Common - ABC-type amino acid transport system, permease and 2 periplasmic domains LACR_1923 198 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116510946 Common - Transposase LACR_0116 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510976 Nonpathogen - hypothetical protein LACR_0150 1 None None None 116513102 Common - NAD-dependent alcohol-acetaldehyde dehydrogenase and iron-containing alcohol dehydrogenase domain LACR_2457 196 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 116511735 Common - Transposase LACR_0986 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513169 Common - Cell shape-determining protein LACR_2535 9 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 116511206 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component LACR_0393 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116511474 Common - Transposase LACR_0705 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511409 Common - Predicted membrane protein LACR_0636 2 COG3326 COG3326, Predicted membrane protein Function unknown 116512069 Common - Tryptophan-rich sensory protein LACR_1341 54 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 116513174 Common - permease of the major facilitator superfamily LACR_2540 41 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116510906 Common - Predicted esterase LACR_0073 32 COG0400 COG0400, Predicted esterase General function prediction only 116511950 Common - Transposase LACR_1213 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512885 Common - hypothetical protein LACR_2223 78 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116512864 Common pheT phenylalanyl-tRNA synthetase subunit beta LACR_2200 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 116512897 Common - Predicted Zn-dependent peptidase LACR_2235 110 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 116512834 Common - hypothetical protein LACR_2155 60 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 116512725 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA LACR_2039 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 116512397 Common - Cell division septal protein LACR_1695 13 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 116512955 Nonpathogen - hypothetical protein LACR_2293 2 None None None 116511140 Nonpathogen - hypothetical protein LACR_0326 1 None None None 116511959 Common - Superfamily I DNA or RNA helicase LACR_1222 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 116512488 Nonpathogen - hypothetical protein LACR_1788 1 None None None 116511695 Common - ABC-type antimicrobial peptide transport system, ATPase component LACR_0941 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116512062 Common - Histidinol dehydrogenase LACR_1332 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 116510898 Common - Short-chain dehydrogenase of various substrate specificities LACR_0065 221 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116512817 Nonpathogen - hypothetical protein LACR_2137 1 None None None 116511804 Common - ribonucleotide-diphosphate reductase subunit alpha LACR_1061 212 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 116512004 Common - Dihydrofolate reductase LACR_1270 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116512445 Common - Galactose mutarotase related enzyme LACR_1743 43 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 116512680 Nonpathogen - hypothetical protein LACR_1992 1 None None None 116512099 Common - D-alanine--poly(phosphoribitol) ligase subunit 2 LACR_1372 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116512353 Common - Glycerol dehydrogenase LACR_1650 66 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 116512092 Common - Transposase LACR_1365 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510964 Common - hypothetical protein LACR_0137 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 116511298 Common - phosphomethylpyrimidine kinase LACR_0492 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 116512979 Common - carbamate kinase LACR_2318 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 116512620 Nonpathogen - hypothetical protein LACR_1930 1 None None None 116513227 Nonpathogen - hypothetical protein LACR_2610 1 None None None 116512748 Common - Actin-like ATPase for cell division LACR_2063 180 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 116511967 Nonpathogen - hypothetical protein LACR_1231 1 None None None 116510933 Common - phospho-2-dehydro-3-heoxyheptonate aldolase LACR_0102 110 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 116512507 Common - DNA structure-specific ATPase for suppression of recombination, MutS family LACR_1809 207 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 116511077 Common - ABC-type multidrug transport system, ATPase component LACR_0257 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116511825 Common - Transposase LACR_1084 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511895 Common - Uncharacterized phage-associated protein LACR_1155 29 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 116511221 Common - Uncharacterized protein, containing RelA_SpoT domain LACR_0408 57 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 116513046 Common - 50S ribosomal protein L29 LACR_2394 129 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 116512400 Common - Nitrogen regulatory protein PII LACR_1698 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 116513109 Common - N6-adenine-specific methylase LACR_2465 213 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 116512126 Common - hypothetical protein LACR_1404 16 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 116512631 Nonpathogen - hypothetical protein LACR_1941 1 None None None 116510857 Nonpathogen - hypothetical protein LACR_0014 1 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 116512783 Common - surface protein (Ig-like domains) LACR_2102 18 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 116512140 Common - hypothetical protein LACR_1419 2 None None None 116512263 Common - Phosphoribosylanthranilate isomerase LACR_1551 192 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 116513152 Common ruvA Holliday junction DNA helicase motor protein LACR_2516 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 116510987 Common - Predicted CoA-binding protein LACR_0162 124 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 116512988 Common - Superfamily II DNA/RNA helicase, SNF2 family LACR_2328 143 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 116511620 Common - Chromosome segregation ATPase LACR_0863 227 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 116511579 Common - Transcriptional regulator LACR_0820 37 COG1846 MarR, Transcriptional regulators Transcription 116510895 Common - Predicted hydrolase of the HAD superfamily LACR_0062 100 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116513221 Nonpathogen - hypothetical protein LACR_2598 1 None None None 116512073 Common - Transposase LACR_1346 27 None None None 116512712 Common - Universal stress protein UspA related nucleotide-binding protein LACR_2025 108 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116512879 Nonpathogen - hypothetical protein LACR_2217 1 None None None 116511481 Common - Predicted acetyltransferase LACR_0713 27 COG2388 COG2388, Predicted acetyltransferase General function prediction only 116512152 Common - ABC-type sugar transport system, periplasmic component LACR_1435 30 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116511689 Common - SAM-dependent methyltransferase for cell envelope biogenesis LACR_0935 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 116512767 Common - tRNA and rRNA cytosine-C5-methylase LACR_2084 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 116512431 Common - dihydrodipicolinate synthase LACR_1729 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116510886 Common - Lipoate-protein ligase A LACR_0052 81 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 116511051 Common - NUDIX family hydrolase LACR_0227 27 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116511875 Common - Phage Mu protein F like protein LACR_1135 8 None None None 116511713 Common - Predicted metal-sulfur cluster biosynthetic enzyme LACR_0960 148 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 116513133 Common - 6-phosphogluconate dehydrogenase-like protein LACR_2497 181 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 116512094 Common - 5,10-methylenetetrahydrofolate reductase LACR_1367 141 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 116512162 Common - Arsenate reductase related protein, glutaredoxin family LACR_1446 17 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116512740 Nonpathogen - hypothetical protein LACR_2055 1 None None None 116511151 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase LACR_0338 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 116512110 Common - Ribosomal protein L7/L12 LACR_1386 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 116511106 Common - ABC-type cobalt transport system, permease component CbiQ related transporter LACR_0290 87 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 116512567 Common - Phosphoglycerate mutase family protein LACR_1875 52 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116512149 Nonpathogen - hypothetical protein LACR_1429 1 None None None 116512509 Common - Thioredoxin reductase LACR_1811 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 116511056 Common - HD superfamily hydrolase LACR_0232 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 116511805 Common nrdI ribonucleotide reductase stimulatory protein LACR_1062 38 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 116511953 Common - DNA gyrase subunit A LACR_1216 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 116511058 Common - Iojap-like protein LACR_0234 172 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 116513159 Common - Predicted permease LACR_2525 44 COG0730 COG0730, Predicted permeases General function prediction only 116512772 Common - hypothetical protein LACR_2089 2 None None None 116511354 Nonpathogen - Predicted membrane protein LACR_0574 4 COG4640 COG4640, Predicted membrane protein Function unknown 116511389 Common - Acetyltransferase, GNAT family LACR_0615 19 COG0456 RimI, Acetyltransferases General function prediction only 116511939 Nonpathogen - hypothetical protein LACR_1201 1 None None None 116512975 Common - DNA polymerase IV LACR_2314 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 116511993 Nonpathogen - hypothetical protein LACR_1259 1 None None None 116511359 Common def peptide deformylase LACR_0581 204 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 116511405 Common - methionine aminopeptidase LACR_0631 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 116511984 Common - Lyzozyme M1 (1,4-beta-N-acetylmuramidase) LACR_1250 7 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 116513087 Common - hypothetical protein LACR_2438 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 116513057 Common - threonine synthase LACR_2405 133 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 116511526 Common - ABC-type sugar transport system, permease component LACR_0762 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116512222 Common - Predicted membrane protein LACR_1508 10 COG3759 COG3759, Predicted membrane protein Function unknown 116511720 Common - Predicted hydrolase of the HAD superfamily LACR_0968 92 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116511477 Nonpathogen - hypothetical protein LACR_0709 1 None None None 116511466 Common - cell division membrane protein LACR_0695 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 116511264 Common - Mevalonate kinase LACR_0454 97 COG1577 ERG12, Mevalonate kinase Lipid metabolism 116511459 Common - Transcriptional regulator LACR_0688 15 COG1309 AcrR, Transcriptional regulator Transcription 116512255 Common - ABC-type proline/glycine betaine transport system, ATPase component LACR_1542 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 116511239 Common - NhaP-type Na+/H+ and K+/H+ antiporter LACR_0429 104 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 116513162 Common - Predicted hydrolase of the HAD superfamily LACR_2528 45 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 116512370 Common - Glucosamine-6-phosphate isomerase LACR_1667 86 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 116512380 Common - Transposase LACR_1677 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512779 Nonpathogen - hypothetical protein LACR_2098 2 None None None 116511024 Common - dTDP-glucose pyrophosphorylase LACR_0200 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 116511594 Common - NAD(FAD)-dependent dehydrogenase and rhodanese domain LACR_0836 246 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 116511156 Common - Transcriptional regulator LACR_0343 13 COG1846 MarR, Transcriptional regulators Transcription 116512579 Common alaS alanyl-tRNA synthetase LACR_1887 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511559 Common - primosomal protein DnaI LACR_0796 34 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 116511500 Common - Transposase LACR_0733 28 None None None 116512928 Nonpathogen - hypothetical protein LACR_2266 1 None None None 116512591 Common - Predicted HD superfamily hydrolase LACR_1901 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 116513184 Nonpathogen - hypothetical protein LACR_2550 1 None None None 116510917 Common - hypothetical protein LACR_0084 4 None None None 116511629 Common - Phosphoribosylpyrophosphate synthetase LACR_0873 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 116512947 Nonpathogen - hypothetical protein LACR_2285 2 None None None 116513117 Common - Transcriptional regulator, xre family LACR_2474 8 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 116511679 Common - Glycerate kinase LACR_0925 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 116513182 Common - Permease of the major facilitator superfamily LACR_2548 6 None None None 116512638 Common - Di- or tricarboxylate transporter LACR_1949 24 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 116511226 Common - Predicted flavoprotein LACR_0413 97 COG0431 COG0431, Predicted flavoprotein General function prediction only 116513050 Common rpsS 30S ribosomal protein S19 LACR_2398 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 116512368 Common - Acetyl-CoA acetyltransferase LACR_1665 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 116512592 Common rpsT 30S ribosomal protein S20 LACR_1902 146 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 116512993 Common - hypothetical protein LACR_2335 2 None None None 116511344 Common - Arsenate reductase related protein, glutaredoxin family LACR_0545 50 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116511810 Nonpathogen - Amidase LACR_1067 1 None None None 116511493 Common glgA glycogen synthase LACR_0726 140 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 116512749 Common - hypothetical protein LACR_2064 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 116511008 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase LACR_0184 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116511444 Common - Transposase LACR_0673 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513078 Common polC DNA polymerase III PolC LACR_2429 216 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 116511544 Common - hypothetical protein LACR_0780 121 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 116511360 Common - dinucleoside polyphosphate hydrolase LACR_0582 120 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 116512377 Nonpathogen - hypothetical protein LACR_1674 1 None None None 116512520 Nonpathogen - hypothetical protein LACR_1823 1 None None None 116512202 Common - Glycerol uptake facilitator related permease (Major Intrinsic Protein Family) LACR_1487 131 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 116512825 Common - Integrase LACR_2145 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116511958 Common - hypothetical protein LACR_1221 4 None None None 116513208 Common rplM 50S ribosomal protein L13 LACR_2584 222 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 116511727 Common - ATPase component of ABC transporter with duplicated ATPase domains LACR_0976 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116512084 Common - Transposase LACR_1357 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511550 Common - Predicted sugar phosphatase of HAD family LACR_0787 186 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 116511276 Common - Transcriptional regulator LACR_0467 47 COG1737 RpiR, Transcriptional regulators Transcription 116512173 Common - 6-phosphofructokinase LACR_1457 139 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 116512196 Common - hypothetical protein LACR_1481 33 COG4260 COG4260, Putative virion core protein (lumpy skin disease virus) Function unknown 116510969 Common - hypothetical protein LACR_0142 6 COG4367 COG4367, Uncharacterized protein conserved in bacteria Function unknown 116511571 Common - Putative effector of murein hydrolase LrgA LACR_0812 43 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 116511657 Common uvrC excinuclease ABC subunit C LACR_0902 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 116512855 Common - Predicted permease LACR_2191 9 COG0679 COG0679, Predicted permeases General function prediction only 116512340 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase LACR_1637 101 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116512314 Common - Transcriptional regulator LACR_1608 7 COG1309 AcrR, Transcriptional regulator Transcription 116511132 Nonpathogen - hypothetical protein LACR_0318 1 None None None 116512607 Common - Predicted phosphatase LACR_1917 86 COG0546 Gph, Predicted phosphatases General function prediction only 116511034 Common - Predicted membrane protein LACR_0210 5 COG4713 COG4713, Predicted membrane protein Function unknown 116513042 Common rplE 50S ribosomal protein L5 LACR_2390 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 116510925 Common - Guanosine polyphosphate pyrophosphohydrolase/synthetase LACR_0092 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 116512688 Common - Hemolysins related protein, CBS domains LACR_2000 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 116511192 Common - Predicted transcriptional regulator LACR_0379 138 COG1733 COG1733, Predicted transcriptional regulators Transcription 116512654 Common - Transposase LACR_1966 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511180 Common - Predicted membrane protein LACR_0367 13 COG4720 COG4720, Predicted membrane protein Function unknown 116511590 Common - cystathionine gamma-synthase/cystathionine beta-lyase LACR_0831 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 116513091 Common - hypothetical protein LACR_2442 4 COG4703 COG4703, Uncharacterized protein conserved in bacteria Function unknown 116513192 Common - Transcriptional regulator LACR_2558 5 COG1309 AcrR, Transcriptional regulator Transcription 116510955 Common - Transcriptional regulator LACR_0128 19 COG1309 AcrR, Transcriptional regulator Transcription 116512704 Nonpathogen - hypothetical protein LACR_2017 1 None None None 116511468 Common - Isocitrate dehydrogenase LACR_0699 221 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 116511835 Common - D-fructose-6-phosphate amidotransferase LACR_1094 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 116511649 Common - Galactose-1-phosphate uridylyltransferase LACR_0894 6 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 116511423 Nonpathogen - Surface antigen LACR_0651 6 None None None 116512230 Common - Transposase LACR_1516 26 None None None 116511218 Nonpathogen - Dithiol-disulfide isomerase LACR_0405 1 None None None 116512640 Common - hypothetical protein LACR_1951 14 COG4357 COG4357, Uncharacterized conserved protein Function unknown 116513122 Common valS valyl-tRNA synthetase LACR_2479 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511849 Common - hypothetical protein LACR_1108 8 None None None 116510870 Nonpathogen - hypothetical protein LACR_0035 1 None None None 116511740 Common - Transposase LACR_0993 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511012 Common - Predicted Fe-S-cluster redox enzyme LACR_0188 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 116512498 Common - ABC-type sugar transport system, periplasmic component LACR_1798 121 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116512219 Common - Transposase LACR_1505 32 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511518 Common - hypothetical protein LACR_0752 55 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 116512886 Common - hypothetical protein LACR_2224 76 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116513124 Nonpathogen - hypothetical protein LACR_2482 1 None None None 116512758 Nonpathogen - hypothetical protein LACR_2075 1 None None None 116511682 Common - Predicted rRNA methylase LACR_0928 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 116513024 Common - Glycosyltransferase LACR_2371 214 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116511844 Nonpathogen - hypothetical protein LACR_1103 1 None None None 116511414 Common - hypothetical protein LACR_0641 2 COG4980 GvpP, Gas vesicle protein General function prediction only 116511639 Common - Transposase LACR_0884 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513004 Common - Amidase LACR_2348 76 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116513164 Nonpathogen - hypothetical protein LACR_2530 2 COG4990 COG4990, Uncharacterized protein conserved in bacteria Function unknown 116511972 Nonpathogen - hypothetical protein LACR_1236 1 None None None 116511630 Common - Regulator of polyketide synthase expression LACR_0874 4 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 116511382 Common - thymidine kinase LACR_0608 99 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 116511926 Common - hypothetical protein LACR_1186 181 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 116511652 Common - hypothetical protein LACR_0897 9 None None None 116511898 Common - ATPase component of ABC transporter with duplicated ATPase domains LACR_1158 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116510949 Nonpathogen - hypothetical protein LACR_0120 1 None None None 116512486 Nonpathogen - hypothetical protein LACR_1786 1 None None None 116511585 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit LACR_0826 188 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 116511373 Common - Transposase LACR_0598 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512937 Common - Integrase LACR_2275 134 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116511337 Common - Cysteine synthase LACR_0537 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 116512355 Common - Dipeptidase LACR_1652 25 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 116512615 Nonpathogen - hypothetical protein LACR_1925 1 None None None 116512866 Common - Transposase LACR_2203 27 None None None 116510931 Common - Transcriptional regulator LACR_0099 14 COG1846 MarR, Transcriptional regulators Transcription 116511587 Common - acetyl-CoA carboxylase biotin carboxylase subunit LACR_0828 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 116511602 Common - hypothetical protein LACR_0844 6 None None None 116513212 Common - Signal peptidase I LACR_2588 136 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 116513101 Common - 3-carboxymuconate cyclase LACR_2456 56 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 116510932 Common secA preprotein translocase subunit SecA LACR_0101 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 116512064 Common - ATP phosphoribosyltransferase for histidine biosynthesis LACR_1335 221 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 116512564 Common - Transposase LACR_1872 31 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511142 Common - Acetyltransferase LACR_0328 119 COG0456 RimI, Acetyltransferases General function prediction only 116512964 Nonpathogen - hypothetical protein LACR_2302 1 None None None 116512195 Common - hypothetical protein LACR_1479 9 None None None 116510899 Common - Transcriptional regulator LACR_0066 32 COG1309 AcrR, Transcriptional regulator Transcription 116512287 Common - hypothetical protein LACR_1578 7 None None None 116511798 Common - Uncharacterized domain/protein associated with RNase G and E LACR_1055 16 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 116511853 Common - Holliday junction resolvase LACR_1112 3 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 116511509 Common - Transcriptional regulator LACR_0742 85 COG1846 MarR, Transcriptional regulators Transcription 116512005 Common - hypothetical protein LACR_1271 2 None None None 116512231 Nonpathogen - hypothetical protein LACR_1517 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 116511433 Common - Transposase LACR_0662 135 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512832 Common - NUDIX family hydrolase LACR_2153 13 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116510852 Common - hypothetical protein LACR_0009 9 None None None 116512723 Nonpathogen - hypothetical protein LACR_2036 1 None None None 116511228 Common - Transposase LACR_0415 20 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512808 Common - Single-stranded DNA-binding protein LACR_2128 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 116511320 Common - Transposase LACR_0516 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512075 Common - Arabinose efflux permease LACR_1348 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511970 Nonpathogen - hypothetical protein LACR_1234 2 None None None 116511349 Common tig trigger factor LACR_0550 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 116511781 Common - Transposase LACR_1037 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512447 Common - mannonate dehydratase LACR_1745 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 116511075 Common - hypothetical protein LACR_0254 43 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 116510928 Common - Predicted hydrolase (HAD superfamily) LACR_0096 37 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116512102 Common - Thiamine monophosphate synthase LACR_1375 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 116511269 Common - Carbon starvation protein, predicted membrane protein LACR_0459 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 116512752 Common - Glycine/D-amino acid oxidase (deaminating) LACR_2067 16 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116511537 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase LACR_0773 119 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 116511873 Common - Phage terminase, large subunit LACR_1133 24 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 116511730 Common - ABC transporter, permease protein LACR_0981 3 None None None 116512582 Common - oligoendopeptidase F LACR_1890 86 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 116512953 Common - Ribosome recycling factor LACR_2291 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 116511247 Common - Uncharacterized NAD(FAD)-dependent dehydrogenase LACR_0437 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 116510963 Common - Predicted metal-dependent membrane protease LACR_0136 3 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 116512382 Common - Integrase LACR_1679 30 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116513038 Common rplF 50S ribosomal protein L6 LACR_2386 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 116512823 Nonpathogen - Predicted Zn peptidase LACR_2143 1 None None None 116513143 Common - Predicted aminoglycoside phosphotransferase LACR_2507 16 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 116511788 Common - Crp-like transcriptional regulator LACR_1045 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116511530 Common - Transcriptional regulator LACR_0766 122 COG1609 PurR, Transcriptional regulators Transcription 116513098 Common - septation ring formation regulator EzrA LACR_2453 19 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 116513172 Common - ribose-5-phosphate isomerase A LACR_2538 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 116511240 Nonpathogen - hypothetical protein LACR_0430 1 None None None 116510979 Nonpathogen - hypothetical protein LACR_0153 1 None None None 116511907 Common - Transposase LACR_1167 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512212 Nonpathogen - hypothetical protein LACR_1497 1 None None None 116511488 Common - elongation factor P LACR_0720 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 116512419 Common - gamma-glutamyl kinase LACR_1717 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 116511775 Common - lactose transport regulator LACR_1031 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 116511916 Common - Predicted hydrolase of the HAD superfamily LACR_1176 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116511979 Common - Transcriptional regulator LACR_1243 167 COG1737 RpiR, Transcriptional regulators Transcription 116512982 Common - ornithine carbamoyltransferase LACR_2321 227 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 116512961 Common - Transposase LACR_2299 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511486 Common ksgA dimethyladenosine transferase LACR_0718 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 116512014 Common - homoserine dehydrogenase LACR_1280 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 116512571 Common - ABC-type phosphate transport system, permease component LACR_1879 233 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 116512462 Common - hypothetical protein LACR_1762 5 COG4722 COG4722, Phage-related protein Function unknown 116511065 Common - Predicted nucleoside-diphosphate sugar epimerase LACR_0241 16 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116512914 Common - Collagenase related protease LACR_2252 121 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 116512409 Common - Protein-tyrosine-phosphatase LACR_1707 133 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 116512119 Common scpB segregation and condensation protein B LACR_1397 149 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 116512066 Common - Steroid 5-alpha reductase family enzyme LACR_1337 34 COG3752 COG3752, Predicted membrane protein Function unknown 116512602 Common - ABC-type antimicrobial peptide transport system, permease component LACR_1912 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116512970 Common - Transcriptional regulator/sugar kinase LACR_2309 163 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116512404 Common - Predicted nucleic acid-binding protein LACR_1702 15 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 116512532 Common - SAM-dependent methyltransferase LACR_1836 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116512130 Common - Acetyltransferase (isoleucine patch superfamily) LACR_1408 202 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116512557 Common - mannose-specific PTS system component IIC LACR_1864 35 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 116511998 Common - hypothetical protein LACR_1264 3 None None None 116512819 Nonpathogen - hypothetical protein LACR_2139 1 None None None 116512457 Common - hypothetical protein LACR_1756 4 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 116512454 Nonpathogen - hypothetical protein LACR_1752 1 None None None 116511693 Nonpathogen - hypothetical protein LACR_0939 1 None None None 116512468 Common - hypothetical protein LACR_1768 5 None None None 116513062 Common - Membrane carboxypeptidase (penicillin-binding protein) LACR_2410 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 116510862 Common - Phosphotransferase system, mannitol-specific IIBC component LACR_0027 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 116511883 Common - hypothetical protein LACR_1143 7 None None None 116510867 Nonpathogen - hypothetical protein LACR_0032 1 None None None 116511464 Common - permease of the major facilitator superfamily LACR_0693 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511470 Common - hypothetical protein LACR_0701 2 None None None 116512010 Common - Dihydropteroate synthase related enzyme LACR_1276 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 116511940 Common - nicotinate phosphoribosyltransferase LACR_1202 125 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 116512281 Common - 1-deoxy-D-xylulose-5-phosphate synthase LACR_1572 203 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 116510849 Common - Transcriptional regulator, xre family LACR_0006 13 COG1396 HipB, Predicted transcriptional regulators Transcription 116511397 Common - rRNA methylase LACR_0623 210 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 116511041 Common - Glycosyltransferase LACR_0217 197 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116511808 Common - DNA topoisomerase IV subunit B LACR_1065 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 116512674 Common - Membrane protein for polysaccharide transport LACR_1986 47 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116512178 Common - UDP-glucose pyrophosphorylase LACR_1462 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 116512322 Common - amidophosphoribosyltransferase LACR_1618 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 116511900 Common pyrC dihydroorotase LACR_1160 213 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 116511969 Nonpathogen - hypothetical protein LACR_1233 2 None None None 116512307 Common - Predicted hydrolase of the HAD superfamily LACR_1600 9 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116510940 Common - Surface antigen LACR_0110 8 None None None 116512471 Nonpathogen - hypothetical protein LACR_1771 1 None None None 116511087 Nonpathogen - hypothetical protein LACR_0269 2 None None None 116512921 Nonpathogen - hypothetical protein LACR_2259 2 None None None 116512364 Common - Protoheme ferro-lyase (ferrochelatase) LACR_1661 155 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 116511314 Nonpathogen - hypothetical protein LACR_0509 1 None None None 116510915 Common - recombination factor protein RarA LACR_0082 245 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 116513082 Common - Predicted membrane-associated Zn-dependent protease 1 LACR_2433 206 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 116512700 Common - Predicted dehydrogenase related protein LACR_2013 126 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116512275 Common - Uncharacterized membrane protein LACR_1566 69 COG1814 COG1814, Uncharacterized membrane protein Function unknown 116511767 Common - D-alanyl-D-alanine carboxypeptidase LACR_1023 34 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116511633 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase LACR_0878 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116512184 Common - orotidine 5'-phosphate decarboxylase LACR_1468 165 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 116511622 Nonpathogen - hypothetical protein LACR_0865 1 None None None 116510919 Nonpathogen - hypothetical protein LACR_0086 1 None None None 116512844 Common - N-acetylmuramoyl-L-alanine amidase LACR_2167 57 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 116510859 Common - tRNA(Ile)-lysidine synthetase, MesJ LACR_0016 203 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 116513148 Common - Glutamine synthetase LACR_2512 230 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 116512513 Common - hypothetical protein LACR_1815 7 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 116512895 Common - Phosphatidylglycerophosphate synthase LACR_2233 202 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 116512549 Nonpathogen - hypothetical protein LACR_1856 1 None None None 116511924 Common - Phosphate starvation-inducible protein PhoH, predicted ATPase LACR_1184 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 116511752 Common - Cell wall-associated hydrolase LACR_1008 139 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 116513089 Common - Glycosyltransferase LACR_2440 71 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116511864 Nonpathogen - hypothetical protein LACR_1123 1 None None None 116512035 Common - tRNA (uracil-5-)-methyltransferase Gid LACR_1303 193 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 116512629 Common - F0F1-type ATP synthase, subunit c LACR_1939 3 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 116512331 Common - Short-chain alcohol dehydrogenase of unknown specificity LACR_1627 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116512977 Common - Amino acid transporter LACR_2316 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 116511209 Common - Superfamily II DNA and RNA helicase LACR_0396 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 116511616 Common - Acetylglutamate kinase LACR_0859 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 116511208 Common prfC peptide chain release factor 3 LACR_0395 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 116513056 Common - Na+-driven multidrug efflux pump LACR_2404 131 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 116511241 Common - tyrosyl-tRNA synthetase LACR_0431 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511165 Common - Transposase LACR_0352 31 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511306 Nonpathogen - hypothetical protein LACR_0501 1 None None None 116511937 Common - Chloride channel protein EriC LACR_1199 164 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 116512058 Common - Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase LACR_1328 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 116513068 Common - Transposase LACR_2416 24 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512991 Nonpathogen - hypothetical protein LACR_2332 1 None None None 116512981 Common - Amino acid transporter LACR_2320 91 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 116511830 Common - Glycosyltransferase LACR_1089 145 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116512949 Common - hypothetical protein LACR_2287 12 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 116511573 Common nusA transcription elongation factor NusA LACR_0814 220 COG0195 NusA, Transcription elongation factor Transcription 116511837 Common - Integrase LACR_1096 110 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116511982 Common - Predicted transcriptional regulator LACR_1248 18 COG1475 Spo0J, Predicted transcriptional regulators Transcription 116512420 Common - hypothetical protein LACR_1718 24 COG2461 COG2461, Uncharacterized conserved protein Function unknown 116513186 Nonpathogen - hypothetical protein LACR_2552 1 None None None 116512594 Common - Phosphoglycerate mutase family protein LACR_1904 112 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116512884 Nonpathogen - hypothetical protein LACR_2222 1 None None None 116511282 Common - Pyruvate:ferredoxin oxidoreductase, fusion of alpha, beta and gamma subunit LACR_0475 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 116512851 Common upp uracil phosphoribosyltransferase LACR_2185 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 116511728 Common - Na+/malate symporter LACR_0978 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 116512261 Common - tryptophan synthase subunit beta LACR_1549 228 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 116511237 Common - Acyl carrier protein phosphodiesterase LACR_0427 97 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 116511491 Common - 4-alpha-glucanotransferase LACR_0723 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 116510966 Common - hypothetical protein LACR_0139 14 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 116511888 Common - Phage-associated peptidase (family M23/M37) LACR_1148 186 COG4926 PblB, Phage-related protein Function unknown 116511496 Common - amylopullulanase LACR_0729 160 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116513060 Common rpmG 50S ribosomal protein L33 LACR_2408 38 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 116512108 Common - permease of the major facilitator superfamily LACR_1383 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116512681 Common - Transposase LACR_1993 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513096 Common - Transcriptional regulator LACR_2447 122 COG1609 PurR, Transcriptional regulators Transcription 116510927 Common - Predicted integral membrane protein LACR_0095 25 COG3548 COG3548, Predicted integral membrane protein Function unknown 116511786 Common - Copper chaperone LACR_1043 21 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 116512333 Common - Transcriptional regulator LACR_1629 31 COG1846 MarR, Transcriptional regulators Transcription 116512320 Nonpathogen - Surface antigen LACR_1614 3 None None None 116512636 Nonpathogen - hypothetical protein LACR_1947 1 None None None 116511419 Common - hypothetical protein LACR_0646 32 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116512858 Common - hypothetical protein LACR_2194 131 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 116513213 Nonpathogen - hypothetical protein LACR_2589 1 None None None 116510893 Common - Amino acid transporter LACR_0060 140 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 116512366 Common rpsP 30S ribosomal protein S16 LACR_1663 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 116510985 Common - Predicted integral membrane protein LACR_0160 6 COG5523 COG5523, Predicted integral membrane protein Function unknown 116512646 Nonpathogen - hypothetical protein LACR_1957 1 None None None 116512860 Nonpathogen - hypothetical protein LACR_2196 1 None None None 116513010 Common - hypothetical protein LACR_2355 2 COG4817 COG4817, Uncharacterized protein conserved in bacteria Function unknown 116511715 Common - Transposase LACR_0962 32 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512128 Common gltD glutamate synthase subunit beta LACR_1406 192 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 116512940 Common - ABC-type multidrug transport system, ATPase component LACR_2278 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116512375 Common - Transposase LACR_1672 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511645 Common - Copper chaperone LACR_0890 86 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 116511158 Common - Predicted transcriptional regulator LACR_0345 54 COG1695 COG1695, Predicted transcriptional regulators Transcription 116512164 Common - hypothetical protein LACR_1448 130 None None None 116511846 Nonpathogen - hypothetical protein LACR_1105 2 None None None 116513029 Common rpsM 30S ribosomal protein S13 LACR_2377 233 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 116512318 Common - ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones LACR_1612 222 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 116511255 Common tdk thymidylate kinase LACR_0445 232 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 116512500 Common - ABC-type ribose transport system, auxiliary component LACR_1801 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 116511322 Common dnaE DNA polymerase III DnaE LACR_0519 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 116512154 Common - Transposase LACR_1437 28 None None None 116511069 Common - Predicted transcriptional regulator LACR_0245 29 COG0789 SoxR, Predicted transcriptional regulators Transcription 116511053 Nonpathogen - hypothetical protein LACR_0229 1 None None None 116511811 Common - DNA polymerase III, epsilon subunit related 3'-5' exonuclease LACR_1068 184 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 116512218 Common - Transposase LACR_1504 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512541 Common - alpha-glucosidase LACR_1848 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116511289 Common - beta-glucoside-specific PTS system IIABC component LACR_0482 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 116513139 Common rpsF 30S ribosomal protein S6 LACR_2503 180 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 116511168 Common - permease of the major facilitator superfamily LACR_0355 20 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 116511435 Common - Transposase LACR_0664 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512147 Common - lactose transport regulator LACR_1427 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 116511291 Common - Predicted sugar phosphatase of HAD family LACR_0484 182 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 116511403 Common - permease of the major facilitator superfamily LACR_0629 175 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116511827 Common - Transposase LACR_1086 58 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116513120 Common - Transposase LACR_2477 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511005 Common - cellobiose-specific PTS system IIC component LACR_0181 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 116510877 Common - Sulfate permease related transporter (MFS superfamily) LACR_0042 116 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 116511505 Common - Cytochrome bd-type quinol oxidase, subunit 2 LACR_0738 155 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 116511010 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase LACR_0186 78 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 116512308 Common - Phosphoribosylamine-glycine ligase LACR_1601 234 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 116511441 Nonpathogen - hypothetical protein LACR_0670 1 None None None 116511592 Common - hypothetical protein LACR_0833 23 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 116511104 Common - ABC-type cobalt transport system, ATPase component LACR_0288 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 116512224 Common - hypothetical protein LACR_1510 7 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 116510957 Common - Preprotein translocase subunit YidC LACR_0130 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 116511661 Common - Lipopolysaccharide biosynthesis glycosyltransferase LACR_0907 8 None None None 116513017 Nonpathogen - hypothetical protein LACR_2362 1 None None None 116512273 Common - Predicted membrane protein LACR_1561 17 COG3759 COG3759, Predicted membrane protein Function unknown 116512361 Common trmD tRNA (guanine-N(1)-)-methyltransferase LACR_1658 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 116512746 Common - Predicted enzyme with a TIM-barrel fold LACR_2061 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 116513006 Common - Transposase LACR_2350 26 None None None 116512071 Common - Transposase LACR_1343 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512387 Common - Retron-type reverse transcriptase LACR_1685 90 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 116512915 Nonpathogen - hypothetical protein LACR_2253 1 None None None 116511384 Common prfA peptide chain release factor 1 LACR_0610 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 116512250 Common - Predicted transcriptional regulator LACR_1537 18 COG1475 Spo0J, Predicted transcriptional regulators Transcription 116512706 Nonpathogen - hypothetical protein LACR_2019 1 None None None 116511153 Common - Peroxiredoxin LACR_0340 99 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116511451 Common - Transposase LACR_0680 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511542 Nonpathogen - hypothetical protein LACR_0778 1 None None None 116512698 Common - Predicted endonuclease, URI domain LACR_2011 60 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 116512838 Common - hypothetical protein LACR_2159 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 116511975 Common - Malate/lactate dehydrogenase LACR_1239 146 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 116512652 Nonpathogen - hypothetical protein LACR_1964 1 None None None 116511096 Nonpathogen - hypothetical protein LACR_0279 1 None None None 116512312 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase LACR_1605 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 116511080 Common - Predicted flavoprotein LACR_0262 156 COG2081 COG2081, Predicted flavoproteins General function prediction only 116512204 Common - cell surface protein LACR_1489 8 None None None 116511596 Common - Arsenate reductase related protein, glutaredoxin family LACR_0838 79 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116511706 Common - Nicotinamide mononucleotide transporter LACR_0952 18 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 116512175 Common - Uncharacterized protein for tellurite resistance LACR_1459 42 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 116512237 Common - Signal transduction histidine kinase LACR_1524 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116511902 Common - Transposase LACR_1162 27 None None None 116512904 Common - UDP-glucose 4-epimerase LACR_2242 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 116513131 Common recX recombination regulator RecX LACR_2490 30 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 116510881 Common recO DNA repair protein RecO LACR_0047 31 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 116512986 Common murC UDP-N-acetylmuramate--L-alanine ligase LACR_2326 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 116511877 Common - hypothetical protein LACR_1137 5 None None None 116511211 Common asnB asparagine synthetase B LACR_0398 146 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 116512241 Common - Cytidine deaminase LACR_1528 111 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 116512257 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase LACR_1544 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116511036 Common - Lipopolysaccharide biosynthesis protein LACR_0212 22 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 116512605 Common - hypothetical protein LACR_1915 7 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 116511134 Common - hypothetical protein LACR_0320 12 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 116511921 Common - Predicted ribosomal protein LACR_1181 18 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 116512761 Common - NUDIX family hydrolase LACR_2078 172 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 116512544 Common - Trehalose-6-phosphate hydrolase LACR_1851 160 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116511791 Common - hypothetical protein LACR_1048 90 COG0391 COG0391, Uncharacterized conserved protein Function unknown 116512950 Common - methionine sulfoxide reductase A LACR_2288 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 116510942 Common - Membrane transporter of cations and cationic drugs LACR_0112 146 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 116512611 Common aroE shikimate 5-dehydrogenase LACR_1921 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 116511963 Common - Transposase LACR_1227 27 None None None 116512822 Common - Transcriptional regulator, xre family LACR_2142 31 COG1396 HipB, Predicted transcriptional regulators Transcription 116510961 Common - Transcriptional regulator, xre family LACR_0134 15 COG1476 COG1476, Predicted transcriptional regulators Transcription 116511750 Common - hypothetical protein LACR_1006 94 COG0393 COG0393, Uncharacterized conserved protein Function unknown 116512449 Common - Transcriptional regulator LACR_1747 118 COG1802 GntR, Transcriptional regulators Transcription 116511539 Common - Acetyltransferase, including N-acetylase of ribosomal protein LACR_0775 64 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116512584 Common - hypothetical protein LACR_1892 29 COG1434 COG1434, Uncharacterized conserved protein Function unknown 116511125 Nonpathogen - hypothetical protein LACR_0311 1 None None None 116512829 Common - Predicted membrane protein LACR_2149 7 COG2261 COG2261, Predicted membrane protein Function unknown 116511710 Common - Transcriptional regulator LACR_0956 25 COG1309 AcrR, Transcriptional regulator Transcription 116511182 Common - ABC-type cobalt transport system, permease component CbiQ related transporter LACR_0369 49 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 116512536 Common - 1-deoxy-D-xylulose-5-phosphate synthase LACR_1843 209 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 116511356 Common - ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones LACR_0578 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 116512951 Common - Predicted RNA-binding protein, S1-like domain LACR_2289 41 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 116511699 Common rplS 50S ribosomal protein L19 LACR_0945 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 116511899 Common pyrE orotate phosphoribosyltransferase LACR_1159 195 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 116512910 Common - Oxidoreductase of aryl-alcohol dehydrogenase family LACR_2248 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116511820 Nonpathogen - hypothetical protein LACR_1079 2 None None None 116512422 Common - Predicted membrane protein LACR_1720 9 COG4392 COG4392, Predicted membrane protein Function unknown 116512663 Common - UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase LACR_1975 224 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 116513179 Common - 16S rRNA uridine-516 pseudouridylate synthase related pseudouridylate synthase LACR_2545 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 116511532 Nonpathogen - hypothetical protein LACR_0768 1 None None None 116513106 Common - Transposase LACR_2462 27 None None None 116511692 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase LACR_0938 215 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 116511704 Common - hypothetical protein LACR_0950 5 COG3247 HdeD, Uncharacterized conserved protein Function unknown 116512510 Common - catabolite control protein A LACR_1812 129 COG1609 PurR, Transcriptional regulators Transcription 116513170 Common - Cell shape-determining protein LACR_2536 93 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 116512750 Common - rRNA methylase LACR_2065 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 116511749 Common - hypothetical protein LACR_1005 34 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 116512429 Common - Predicted hydrolase of the metallo-beta-lactamase superfamily LACR_1727 158 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 116512768 Nonpathogen - hypothetical protein LACR_2085 1 None None None 116511198 Common - Cell division protein FtsI/penicillin-binding protein 2 LACR_0385 203 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 116512414 Common - pyrimidine regulatory protein PyrR LACR_1712 128 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 116512744 Common - Cell division membrane protein LACR_2059 20 None None None 116512715 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component LACR_2028 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116512433 Common - aspartate-semialdehyde dehydrogenase LACR_1731 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 116511739 Common - Transposase LACR_0992 32 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512008 Common - Dihydroneopterin aldolase LACR_1274 60 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 116511650 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase LACR_0895 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 116512357 Common - Predicted acetyltransferase LACR_1654 26 COG3981 COG3981, Predicted acetyltransferase General function prediction only 116510902 Common - Short-chain dehydrogenase of various substrate specificities LACR_0069 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116512846 Common - Predicted membrane protein LACR_2180 128 COG2860 COG2860, Predicted membrane protein Function unknown 116511928 Common - hypothetical protein LACR_1188 26 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 116511202 Common - ABC-type oligopeptide transport system, periplasmic component LACR_0389 176 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 116512392 Common - cell surface protein LACR_1690 6 None None None 116513154 Common - hypothetical protein LACR_2518 7 None None None 116511144 Common - O-sialoglycoprotein endopeptidase LACR_0330 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 116512785 Common - NAD+--asparagine ADP-ribosyltransferase LACR_2104 9 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 116512267 Nonpathogen - hypothetical protein LACR_1555 1 None None None 116511245 Common - Thiol-disulfide isomerase and thioredoxin LACR_0435 108 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 116511831 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_1090 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116512440 Common - Transposase LACR_1738 26 None None None 116511171 Common - hypothetical protein LACR_0358 96 COG2606 EbsC, Uncharacterized conserved protein Function unknown 116512729 Common cysS cysteinyl-tRNA synthetase LACR_2043 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116512847 Common - Threonyl-tRNA synthetase LACR_2181 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511942 Common nadE NAD synthetase LACR_1204 145 COG0171 NadE, NAD synthase Coenzyme metabolism 116512840 Common - S-adenosylmethionine synthetase LACR_2161 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 116511375 Common - hypothetical protein LACR_0600 2 None None None 116511796 Common - Transposase LACR_1053 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 116512003 Nonpathogen - hypothetical protein LACR_1269 1 None None None 116513086 Common - Predicted DNA alkylation repair enzyme LACR_2437 15 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 116512145 Common - Type I restriction-modification system methyltransferase subunit LACR_1424 51 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 116512394 Nonpathogen - hypothetical protein LACR_1692 1 None None None 116512484 Nonpathogen - hypothetical protein LACR_1784 1 None None None 116512931 Common - Transcriptional regulator, xre family LACR_2269 14 COG1396 HipB, Predicted transcriptional regulators Transcription 116511149 Common - ABC-type phosphate/phosphonate transport system, permease component LACR_0336 150 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 116511118 Common - Uncharacterized phage-encoded protein LACR_0304 5 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 116511122 Nonpathogen - hypothetical protein LACR_0308 1 None None None 116512830 Common fmt methionyl-tRNA formyltransferase LACR_2150 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 116512721 Nonpathogen - hypothetical protein LACR_2034 1 None None None 116510938 Nonpathogen - Serine hydroxymethyltransferase/Phosphoribosyl-dephospho-CoA transferase family enzyme LACR_0107 1 None None None 116512082 Common - Transcriptional regulator LACR_1355 88 COG1737 RpiR, Transcriptional regulators Transcription 116511605 Common - Predicted membrane protein LACR_0847 15 COG4708 COG4708, Predicted membrane protein Function unknown 116512157 Common - Predicted lactoylglutathione lyase LACR_1441 40 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 116512917 Nonpathogen - hypothetical protein LACR_2255 1 None None None 161777614 Common - putative lipid kinase LACR_0473 105 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 116512473 Nonpathogen - hypothetical protein LACR_1773 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 116511177 Common - ABC-type metal ion transport system, periplasmic component/surface antigen LACR_0364 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 116511647 Nonpathogen - hypothetical protein LACR_0892 1 None None None 116511660 Common - Transposase LACR_0906 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116511866 Nonpathogen - hypothetical protein LACR_1125 1 None None None 116511667 Common - ABC-type proline/glycine betaine transport system, ATPase component LACR_0913 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 116511390 Common - Putative translation factor (SUA5) LACR_0616 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 116512193 Common - ABC-type sugar transport system, permease component LACR_1477 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116512702 Common - Predicted pyrophosphatase LACR_2015 15 COG1694 MazG, Predicted pyrophosphatase General function prediction only 116512190 Common - 3-oxoacyl-acyl carrier protein reductase LACR_1474 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116511765 Common - hypothetical protein LACR_1021 9 None None None 116512515 Common - Cell division initiation protein LACR_1818 10 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 116512893 Nonpathogen - hypothetical protein LACR_2231 1 None None None 116510997 Common - Amidase family enzyme LACR_0172 201 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 116512739 Common - elongation factor Tu LACR_2054 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 116513160 Common - hypothetical protein LACR_2526 2 None None None 116511167 Common - Dinucleotide-utilizing enzyme for molybdopterin and thiamine biosynthesis LACR_0354 44 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 116511098 Common - Predicted phage phi-C31 gp36 major capsid-like protein LACR_0281 15 None None None 116512998 Common - Predicted metal-dependent membrane protease LACR_2340 4 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 116510972 Common - 1,4-alpha-glucan branching enzyme LACR_0145 156 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 116512547 Common - ABC-type sugar transport system, permease component LACR_1854 136 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116513080 Common - Uncharacterized NAD(FAD)-dependent dehydrogenase LACR_2431 248 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 116511614 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein LACR_0857 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 116510913 Nonpathogen - Uncharacterized membrane-anchored protein conserved in bacteria LACR_0080 1 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 116513195 Common - Predicted metal-dependent membrane protease LACR_2561 17 None None None 116512627 Common - F0F1-type ATP synthase, subunit b LACR_1937 162 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 116512182 Common gidB glucose-inhibited division protein B LACR_1466 202 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 116513054 Common - Ribosomal protein S10 LACR_2402 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 116512873 Common - Transposase LACR_2211 26 None None None 116511304 Common - hypothetical protein LACR_0499 2 None None None 116511589 Common - Acetyl-CoA carboxylase alpha subunit LACR_0830 180 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 116512181 Common - Geranylgeranyl pyrophosphate synthase LACR_1465 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 116512305 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit LACR_1598 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 116511909 Nonpathogen - hypothetical protein LACR_1169 1 None None None 116512559 Common - hypothetical protein LACR_1866 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 116511339 Common - Zn-dependent hydrolase, including glyoxylase LACR_0539 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116512117 Common - Predicted membrane protein LACR_1395 16 COG3601 COG3601, Predicted membrane protein Function unknown 116511677 Common - Exonuclease VII small subunit LACR_0923 73 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 116511421 Common - Galactose-1-phosphate uridyltransferase related protein LACR_0648 4 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 116512634 Common - ABC-type Na+ efflux pump, permease component LACR_1945 39 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 116512562 Common - seryl-tRNA synthetase LACR_1870 246 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 116511914 Common - hypothetical protein LACR_1174 111 COG0327 COG0327, Uncharacterized conserved protein Function unknown 116513000 Common - x-prolyl-dipeptidyl aminopeptidase LACR_2342 13 COG2936 COG2936, Predicted acyl esterases General function prediction only 116512586 Common - Predicted hydrolase of the HAD superfamily LACR_1895 109 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 116512534 Common - Transposase LACR_1841 28 None None None 116511484 Common - Adenylate kinase related kinase LACR_0716 19 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 116512943 Nonpathogen - hypothetical protein LACR_2281 2 None None None 116511479 Common - Predicted xylanase/chitin deacetylase LACR_0711 70 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116512016 Common - hypothetical protein LACR_1282 6 None None None 116512617 Nonpathogen - hypothetical protein LACR_1927 1 None None None 116512407 Common - Surface antigen LACR_1705 14 COG3942 COG3942, Surface antigen General function prediction only 116512686 Common - putative manganese-dependent inorganic pyrophosphatase LACR_1998 53 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 116513047 Common rplP 50S ribosomal protein L16 LACR_2395 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 116511885 Nonpathogen - hypothetical protein LACR_1145 2 None None None 116511230 Common lysS lysyl-tRNA synthetase LACR_0417 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 116512259 Nonpathogen - hypothetical protein LACR_1547 1 None None None 116512466 Common - hypothetical protein LACR_1766 7 None None None 116511655 Common - Uridine phosphorylase LACR_0900 98 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 116512122 Common - CBS domain containing protein LACR_1400 13 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 116511428 Common - adenine phosphoribosyltransferase LACR_0657 188 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 116511759 Common - Exoribonuclease R LACR_1015 192 COG0557 VacB, Exoribonuclease R Transcription 116512452 Nonpathogen - hypothetical protein LACR_1750 1 None None None 116511416 Common - K+ transporter LACR_0643 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 116511625 Common - Gamma-aminobutyrate permease related permease LACR_0868 138 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 116510864 Common - Mannitol/fructose-specific phosphotransferase system, IIA domain LACR_0029 61 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 116512577 Common - Nitroreductase LACR_1885 80 COG0778 NfnB, Nitroreductase Energy production and conversion 116512478 Common - hypothetical protein LACR_1778 24 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 116510994 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C LACR_0169 114 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 116511472 Nonpathogen - hypothetical protein LACR_0703 1 None None None 116511067 Common - Transcriptional regulator LACR_0243 26 COG1309 AcrR, Transcriptional regulator Transcription 116512649 Common - Dioxygenase LACR_1961 145 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 116512526 Common - Chloride channel protein EriC LACR_1830 160 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 116512041 Common - Acetolactate synthase, small (regulatory) subunit LACR_1310 189 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 116512732 Common - hypothetical protein LACR_2046 2 None None None 116512460 Nonpathogen - hypothetical protein LACR_1759 1 None None None 116512283 Common - Mg2+ or Co2+ transporter LACR_1574 33 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 116512930 Nonpathogen - hypothetical protein LACR_2268 1 None None None 116512672 Common - neutral endopeptidase LACR_1984 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 116512797 Common - hypothetical protein LACR_2116 4 None None None 116512496 Common - Transposase LACR_1796 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116510869 Common - hypothetical protein LACR_0034 2 None None None 116512600 Common - DNA-binding response regulator, OmpR family (Rec-wHTH domains) LACR_1910 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116511640 Common - NADH dehydrogenase, FAD-containing subunit LACR_0885 184 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 116511851 Common - hypothetical protein LACR_1110 6 None None None 116512068 Common - Predicted membrane protein LACR_1340 28 COG4852 COG4852, Predicted membrane protein Function unknown 116512012 Common - Folylpolyglutamate synthase LACR_1278 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 116512037 Common - Predicted Rossmann fold nucleotide-binding protein for DNA uptake LACR_1305 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 116511528 Common - Predicted integral membrane protein LACR_0764 4 COG5578 COG5578, Predicted integral membrane protein Function unknown 116513075 Common - Type II secretory pathway/competence, pseudopilin PulG LACR_2423 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 116510854 Common - Transcription-repair coupling factor LACR_0011 236 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription