Rhizobium leguminosarum bv. viciae 3841, complete genome NC_008380 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 116249959 Nonpathogen - hypothetical protein RL0192 1 None None None 116250192 Common - putative transmembrane protein RL0423 100 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116253982 Common - putative solute-binding component of ABC transporter RL4245 93 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251219 Common - putative transmembrane RND family transporter RL1453 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116251733 Common - putative short-chain dehydrogenase/reductase RL1969 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116252025 Common - hypothetical protein RL2269 35 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116250871 Common hsdM1 putative type I restriction enzyme modification methylase subunit RL1099 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 116252308 Common - putative transmembrane DoxD family protein RL2562 31 COG2259 COG2259, Predicted membrane protein Function unknown 116251103 Common - putative transmembrane multi-drug resistance efflux pump RL1335 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250679 Common - putative GntR family transcriptional regulator RL0905 109 COG1802 GntR, Transcriptional regulators Transcription 116252884 Common - putative transmembrane transporter protein RL3143 83 COG0628 PerM, Predicted permease General function prediction only 116252510 Nonpathogen - putative transmembrane protein RL2764 5 None None None 116254384 Common - hypothetical protein RL4659 18 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 116251157 Nonpathogen - hypothetical protein RL1389 1 None None None 116250637 Common glcD putative glycolate oxidase subunit RL0864 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 116253213 Common - 50S ribosomal protein L25/general stress protein Ctc RL3471 192 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 116251926 Common - hypothetical protein RL2168 31 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 116253903 Common - hypothetical protein RL4166 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 116251226 Common - putative AsnC family transcriptional regulator RL1460 149 COG1522 Lrp, Transcriptional regulators Transcription 116251166 Common - putative TetR family transcriptional regulator RL1398 8 COG1309 AcrR, Transcriptional regulator Transcription 116250215 Common - hypothetical protein RL0446 30 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 116252185 Common - hypothetical protein RL2432 14 COG5569 COG5569, Uncharacterized conserved protein Function unknown 116250069 Common - putative AraC family transcriptional regulator RL0301 90 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 116251239 Common - conserved hypothetical protein with RNA polymerase sigma factor domain RL1473 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 116252612 Nonpathogen - hypothetical protein RL2865 7 None None None 116250128 Common - short chain dehydrogenase RL0359 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253499 Common - putative two-component response regulator transcriptional regulatory protein RL3758 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116250326 Common metZ O-succinylhomoserine sulfhydrylase RL0554 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 116251260 Common iolD putative malonate semialdehyde dehydrogenase RL1494 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 116251877 Nonpathogen - hypothetical protein RL2117A 1 None None None 116251620 Common - putative oxidoreductase RL1854 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250163 Common phoH putative phosphate starvation-induced protein RL0394 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 116253650 Common - putative ATP-binding component of ABC transporter RL3910 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116250520 Common aglA putative alpha-glucosidase RL0748 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116253464 Common - putative efflux protein RL3724 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116250561 Common - hypothetical protein RL0789 12 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 116253407 Nonpathogen - hypothetical protein RL3666 1 None None None 116251050 Common - hypothetical protein RL1283 9 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 116252030 Common - putative NAD binding flavoprotein RL2274 75 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 116253968 Common - putative solute-binding component of ABC transporter RL4231 28 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250269 Common - putative transmembrane protein RL0498 23 COG5500 COG5500, Predicted integral membrane protein Function unknown 116250049 Nonpathogen - putative transmembrane protein RL0281 6 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 116250260 Common - putative solute-binding component of ABC transporter RL0489 94 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250628 Common - putative gamma-glutamylcysteine synthetase precursor RL0855 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 116251886 Nonpathogen - hypothetical protein RL2126 1 None None None 116252554 Common gnd 6-phosphogluconate dehydrogenase RL2807 180 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 116252304 Common pccA putative propionyl-CoA carboxylase alpha subunit RL2558 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 116251595 Common - putative dehydrogenase/oxidoreductase RL1829 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 116252889 Common - putative transcriptional regulator RL3148 10 COG4189 COG4189, Predicted transcriptional regulator Transcription 116252754 Common - putative methyltransferase RL3009 156 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116252277 Common folE GTP cyclohydrolase I RL2531 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 116253603 Common - putative GntR family transcriptional regulator RL3863 127 COG1802 GntR, Transcriptional regulators Transcription 116250400 Common - putative AraC family transcriptional regulator RL0628 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116252337 Common - putative AphC-TSA family protein RL2591 201 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116249770 Common - putative dephospho-CoA kinase RL0004 201 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 116253501 Common - hypothetical protein RL3760 30 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 116253017 Common prkA putative PrkA protein kinase RL3274 70 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 116250330 Common - putative UDP-glucose 4-epimerase RL0559 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 116250734 Common - putative Sua5 family protein RL0960 222 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 116253147 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase RL3405 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 116253721 Common - hypothetical protein RL3982 28 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 116250693 Common - putative LuxR/GerE family transcriptional regulator RL0919 55 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116250785 Common cbpA putative curved DNA-binding protein RL1012 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 116250104 Common - hypothetical protein RL0336 65 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 116252964 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ RL3222 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 116250421 Common - putative PfkB family sugar kinase RL0649 39 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116254457 Common - hypothetical protein RL4733 12 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 116251395 Common - hypothetical protein RL1629 25 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116250218 Common - hypothetical protein RL0449 4 None None None 116252003 Common - putative transmembrane transglycosylase-associated protein RL2247 25 None None None 116252039 Common - D-amino acid aminotransferase RL2283 194 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 116251093 Common - putative alcohol dehydrogenase RL1325 213 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 116249840 Common - hypothetical protein RL0074 5 COG3889 COG3889, Predicted solute binding protein General function prediction only 116251214 Common - putative transmembrane protein RL1448 100 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116252810 Common - putative transmembrane protein RL3066 2 None None None 116252227 Nonpathogen - hypothetical protein RL2480 6 COG4274 COG4274, Uncharacterized conserved protein Function unknown 116250062 Common - putative short-chain dehydrogenase/oxidoreductase RL0294 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116252422 Common - putative integrase/recombinase protein RL2675 110 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116251234 Common - putative transmembrane protein RL1468 9 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116251993 Common - hypothetical protein RL2237 16 None None None 116254166 Common - hypothetical protein RL4434 9 None None None 116251976 Nonpathogen - hypothetical protein RL2220 1 None None None 116254222 Common gpsA putative glycerol-3-phosphate dehydrogenase [NAD(P)+] RL4493 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 116253838 Common - putative transmembrane protein RL4101 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 116251992 Common lexA LexA repressor RL2236 167 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 116250807 Common - hypothetical protein RL1034 33 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 116251496 Common pleD response regulator PleD RL1730 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 116251352 Common pgsA putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase RL1586 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 116253160 Common - hypothetical protein RL3418 14 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 116251487 Common - putative ATP-binding component of ABC transporter RL1721 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116251175 Nonpathogen - hypothetical protein RL1407 1 None None None 116251674 Common - hypothetical protein RL1910 87 COG1262 COG1262, Uncharacterized conserved protein Function unknown 116251005 Common - putative arylsulfatase RL1238 74 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116252456 Common - putative transmembrane protein RL2709 25 COG4292 COG4292, Predicted membrane protein Function unknown 116253787 Common - putative short-chain dehydrogenase/reductase RL4048 223 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252715 Nonpathogen - hypothetical protein RL2968 1 None None None 116252865 Common - putative acetyltransferase RL3123 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116254286 Common - putative two-component response regulator transcriptional regulatory protein RL4559 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116253961 Common - putative HlyD family secretion transport protein RL4224 177 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116251364 Common - hypothetical protein RL1598 65 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 116254052 Common - putative cobalamin adenosultransferase RL4317 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 116252708 Common - putative cation-binding protein RL2961 95 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 116253320 Common guaD guanine deaminase RL3577 157 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 116250139 Common ubiB putative ubiquinone biosynthesis protein RL0370 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 116250485 Common - putative exported flagella related protein RL0713 13 COG3334 COG3334, Uncharacterized conserved protein Function unknown 116252430 Common - putative methyl-accepting chemotaxis protein RL2683 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116252262 Common - putative LysR family transcriptional regulator RL2516 156 COG0583 LysR, Transcriptional regulator Transcription 116252517 Nonpathogen - hypothetical protein RL2771 2 None None None 116250143 Common rpsT putative 30S ribosomal protein S20 RL0374 164 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 116250793 Common - putative invasion associated protein RL1020 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 116252601 Common - putative oxidoreductase RL2854 27 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 116252500 Common - putative transmembrane permease component of ABC transporter RL2754 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 116252044 Common cysG2 putative siroheme synthase RL2288 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 116253821 Common gltD glutamate synthase subunit beta RL4084 199 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 116249786 Common - N-(5'-phosphoribosyl)anthranilate isomerase RL0020 199 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 116251897 Common - putative transoposon resolvase RL2138 54 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 116252671 Common - putative MarR family transcriptional regulator RL2924 108 COG1846 MarR, Transcriptional regulators Transcription 116252691 Common - putative anionic transporter RL2944 163 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 116250499 Common - putative two-component regulator transcriptional regulatory protein RL0727 69 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116251980 Common frr ribosome recycling factor RL2224 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 116251126 Common - putative TetR family transcriptional regulator RL1358 56 COG1309 AcrR, Transcriptional regulator Transcription 116251249 Common - hypothetical protein RL1483 2 None None None 116254059 Nonpathogen - hypothetical protein RL4324 1 None None None 116253129 Common - putative HAD family hydrolase RL3387 130 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116251204 Common ccmF putative cytochrome c-type biogenesis protein RL1438 152 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 116253930 Common - putative transmembrane component of ABC transporter RL4193 129 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116251176 Nonpathogen - hypothetical protein RL1408 3 None None None 116252391 Common - hypothetical protein RL2645 42 COG3106 COG3106, Predicted ATPase General function prediction only 116253989 Common - putative solute-binding component of ABC transporter RL4252 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251829 Common map methionine aminopeptidase RL2069 240 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 116251670 Nonpathogen - hypothetical protein RL1906 1 None None None 116253801 Common - putative amidohydrolase RL4062 40 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 116251244 Common amn AMP nucleosidase RL1478 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 116254437 Common - putative alkaline phosphatase RL4713 85 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 116254197 Common - putative transmembrane component of ABC transporter RL4466 225 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116249857 Common - putative ATP-binding component of ABC transporter RL0091 57 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116249982 Common cpaD putative pilus assembly protein RL0215 15 COG5461 COG5461, Type IV pili component Cell motility and secretion 116251822 Common tig trigger factor RL2062 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 116252216 Nonpathogen - hypothetical protein RL2467 1 None None None 116250365 Common - putative fatty oxidation complex subunit RL0594 163 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 116252202 Common - putative transmembrane component of ABC transporter RL2450 140 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116251345 Common - putative etherase RL1579 17 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116249903 Common - putative MutT/nudix family protein RL0136 102 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 116253049 Common ftsW putative cell division protein FtsW RL3308 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 116253538 Common - putative transmembrane component of ABC transporter RL3797 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116254080 Common - hypothetical protein RL4347 23 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 116253054 Common - putative penicillin binding protein RL3313 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 116251654 Common - putative multicopper oxidase RL1889 99 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 116251480 Common nuoN NADH dehydrogenase subunit N RL1714 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 116252319 Common gcvP glycine dehydrogenase RL2573 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 116253620 Common - putative transmembrane component of ABC transporter RL3880 223 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116253009 Common - hypothetical protein RL3266 15 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 116252934 Common - putative ATP-binding component of ABC transporter RL3192 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116251725 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein RL1961 121 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 116253077 Common - putative transmembrane protein RL3336 126 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 116253412 Common - hypothetical protein RL3671 30 COG0400 COG0400, Predicted esterase General function prediction only 116249937 Common phoC putative ATP-binding component of phosphate uptake ABC transporter RL0170 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 116250670 Common - putative transmembrane transporter RL0896 62 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 116250087 Common - hypothetical protein RL0319 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 116249919 Common dnaK putative heat shock chaperone protein RL0152 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 116251092 Common - hypothetical protein RL1324 23 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116253849 Common - hypothetical protein RL4112 7 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 116250456 Common - putative transmembrane protein RL0684 24 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116250618 Common - putative transmembrane MFS family permease RL0845 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250664 Common - hypothetical protein RL0890 7 None None None 116251371 Common aspS aspartyl-tRNA synthetase RL1605 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116252591 Common - putative solute-binding component of ABC transporter RL2844 141 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 116253002 Common - hypothetical protein RL3259 27 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 116250156 Nonpathogen - hypothetical protein RL0387 1 None None None 116250202 Common fmt methionyl-tRNA formyltransferase RL0433 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 116254397 Common - hypothetical protein RL4672 3 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 116250016 Nonpathogen - hypothetical protein RL0248 1 None None None 116252991 Common - putative GntR family transcriptional regulator RL3248 207 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 116253887 Common - putative acetyltransferase RL4150 25 COG0456 RimI, Acetyltransferases General function prediction only 116251471 Common nqo1 putative NADH-quinone oxidoreductase subunit F RL1705 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 116251636 Common - putative transmembrane cation ATPase transporter RL1871 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116253895 Common - hypothetical protein RL4158 31 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 116250292 Common - putative altronate hydrolase/glucarate dehydratase RL0521 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 116252596 Common - putative 2-pyrone-4,6-dicarboxylic acid hydrolase RL2849 40 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 116250770 Common - putative HTH transcriptional regulator RL0997 192 COG0583 LysR, Transcriptional regulator Transcription 116252015 Common - hypothetical protein RL2259 21 None None None 116250583 Common - putative beta-glycosyltransferase RL0811 176 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116251649 Common - putative phospholipid binding protein RL1884 32 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 116254089 Common - hypothetical protein RL4356 47 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 116251019 Common - putative GntR family transcriptional regulator RL1252 125 COG1609 PurR, Transcriptional regulators Transcription 116252136 Common recG putative ATP-dependent DNA helicase RL2384 214 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 116250042 Common - hypothetical protein RL0274 37 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 116251147 Common rosR putative nodulation competitiveness transcriptional regulator RL1379 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 116253022 Common pncA putative pyrazinamidase/nicotinamidase RL3279 111 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116251658 Nonpathogen - putative transmembrane protein RL1893 4 None None None 116250756 Common - putative transmembrane component of ABC transporter RL0982 139 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116252577 Common cobN cobaltochelatase RL2830 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 116250307 Common fixO putative FixO cytochrome-cbb3 oxidase subunit RL0535 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 116253393 Common - putative glycosyl transferase RL3651 110 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116251554 Common rpsH 30S ribosomal protein S8 RL1788 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 116251813 Common - hypothetical protein RL2053 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 116250960 Common - putative HTH family transcriptional regulator RL1192 30 COG0640 ArsR, Predicted transcriptional regulators Transcription 116250272 Common pyrE orotate phosphoribosyltransferase RL0501 168 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 116252082 Common - putative transposase-related protein RL2329 45 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 116253845 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL4108 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116249882 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase RL0116 82 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 116252841 Common - hypothetical protein RL3100 26 None None None 116251559 Common rplO 50S ribosomal protein L15 RL1793 203 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 116252662 Common - putative methyltransferase RL2915 87 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 116250073 Common - hypothetical protein RL0305 43 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116252698 Common cya putative adenylate cyclase RL2951 80 COG5616 COG5616, Predicted integral membrane protein Function unknown 116250329 Common - putative transmembrane cellulose synthase catalytic subunit [UDP-forming] RL0558 65 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251889 Common - hypothetical protein RL2129 4 None None None 116251749 Nonpathogen - hypothetical protein RL1986 1 None None None 116253343 Common - putative transmembrane fatty acid synthesis protein RL3600 74 COG3000 ERG3, Sterol desaturase Lipid metabolism 116253558 Common - putative glycosyltransferase RL3817 119 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116250999 Common - putative AraC family transcriptional regulator RL1232 118 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116252281 Common - putative rhombiod family transmembrane protein RL2535 47 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 116252682 Common - hypothetical protein RL2935 41 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 116252489 Common - putative transcriptional regulator RL2743 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 116250721 Common purD phosphoribosylamine--glycine ligase RL0947 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 116250023 Common - putative transcriptional regulator RL0255 78 COG0819 TenA, Putative transcription activator Transcription 116252855 Common - hypothetical protein RL3113 24 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116251989 Common lpxB lipid-A-disaccharide synthase RL2233 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 116253627 Common - putative iron transmembrane ABC transporter component RL3887 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 116253759 Common - hypothetical protein RL4020 31 COG3422 COG3422, Uncharacterized conserved protein Function unknown 116253685 Common - putative phage DNA primase/helicase RL3945 13 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 116250197 Common - putative DNA recombination protein RL0428 139 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 116250003 Common - putative carboxymethyl cellulase RL0236 14 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 116252737 Common - hypothetical protein RL2992 5 None None None 116253506 Common rLuD putative ribosomal large subunit pseudouridine synthase D RL3765 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 116252413 Common - putative HlyD family protein RL2667 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116249941 Common phnJ putative phosphonate metabolism protein RL0174 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 116250926 Common - putative two-component response regulator transcriptional regulatory protein RL1157 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116253221 Common - translation-associated GTPase RL3479 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 116249995 Common - putative solute-binding component of ABC transporter RL0228 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116253447 Common gltB putative oxidoreductase RL3707 209 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 116253948 Common - putative transcriptional regulator RL4211 32 COG1737 RpiR, Transcriptional regulators Transcription 116254147 Common - putative transmembrane component of ABC transporter RL4415 216 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116254231 Common - putative transmembrane protein RL4502 31 COG0762 COG0762, Predicted integral membrane protein Function unknown 116252839 Nonpathogen - putative glycine-asparagine rich protein RL3098 2 COG4907 COG4907, Predicted membrane protein Function unknown 116252818 Common rap1A putative autoaggregation protein RL3074 31 None None None 116251063 Common - hypothetical protein RL1296 67 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116253370 Common - hypothetical protein RL3627 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 116250547 Common - hypothetical protein RL0775 17 COG1359 COG1359, Uncharacterized conserved protein Function unknown 116253978 Common - hypothetical protein RL4241 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 116250529 Common - putative methyl-accepting chemotaxis protein RL0757 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116252961 Common - putative MFS permease transmembrane transporter protein RL3219 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253734 Common - putative transmembrane acid tolerance protein RL3995 79 COG2898 COG2898, Uncharacterized conserved protein Function unknown 116250680 Common - putative transmembrane component of ABC transporter RL0906 124 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116251507 Common - putative ribonuclease RL1741 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 116253197 Common - putative MarR family transcriptional regulator RL3455 45 COG1846 MarR, Transcriptional regulators Transcription 116251082 Nonpathogen - hypothetical protein RL1314 1 None None None 116251034 Nonpathogen - putative transmembrane protein RL1267 6 None None None 116251565 Common rplQ 50S ribosomal protein L17 RL1799 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 116251417 Common ubiG putative 3-demethylubiquinone-9 3-methyltransferase RL1651 158 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116250782 Common - hypothetical protein RL1009 6 None None None 116250440 Common - hypothetical protein RL0668 2 None None None 116250728 Common gpmB putative phosphoglycerate mutase RL0954 139 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116253092 Common - putative transmembrane component of ABC transporter RL3351 102 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 116250252 Common - putative 3-oxoacyl-[acyl-carrier-protein] reductase RL0481 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251550 Common rplN 50S ribosomal protein L14 RL1784 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 116250600 Nonpathogen - putative transmembrane protein RL0828 1 None None None 116253329 Common - putative uricase RL3586 50 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 116253068 Common btaB putative S-adenosylmethionine:diacylgycerolhomoserine-N-methyltrans ferase RL3327 79 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116249876 Nonpathogen - hypothetical protein RL0110 7 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 116252346 Common - putative transmembrane protein RL2600 4 None None None 116249827 Common - putative alpha-amylase family protein RL0061 37 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116251012 Nonpathogen - hypothetical protein RL1245 1 None None None 116253551 Common - putative transmembrane component of ABC transporter RL3810 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250091 Common - putative methyltransferase RL0323 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 116251848 Common accC acetyl-CoA carboxylase biotin carboxylase subunit RL2088 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 116252455 Common - putative MarR family transcriptional regulator RL2708 99 COG1846 MarR, Transcriptional regulators Transcription 116250684 Common mutL DNA mismatch repair protein RL0910 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 116253492 Common pssB putative inositol monophosphatase involved in exopolysaccharide production RL3751 189 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 116251185 Common - putative serine protease RL1419 206 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116252350 Common - hypothetical protein RL2604 56 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 116253761 Common - hypothetical protein RL4022 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 116253615 Common rmeB putative RND family transmembrane transporter RL3875 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116250255 Common - putative short-chain oxidoreductase RL0484 140 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253042 Common ddl D-alanine--D-alanine ligase RL3301 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 116252080 Common - putative transmembrane component of ABC transporter RL2327 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116254348 Common aniA putative carbon flux regulator RL4622 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 116250132 Common - putative glyoxalase RL0363 46 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116250659 Common - putative hydrolase RL0885 75 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 116250415 Common agaZ putative tagatose 6-phosphate kinase RL0643 31 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 116250432 Common - nitrilase RL0660 104 COG0388 COG0388, Predicted amidohydrolase General function prediction only 116252479 Common - putative LysR family transcriptional regulator RL2733 124 COG0583 LysR, Transcriptional regulator Transcription 116254376 Common - putative solute-binding component of ABC transporter RL4651 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116252389 Common dksA putative DnaK suppressor protein RL2643 160 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 116253351 Common - hypothetical protein RL3608 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 116253573 Common gcd putative transmembrane glucose dehydrogenase RL3832 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 116252363 Common - putative transmembrane efflux protein RL2617 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116249985 Common - putative pilus assembly protein RL0218 87 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 116251044 Common - putative transmembrane transporter protein RL1277 167 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253639 Common - putative transmembrane GGDEF/EAL sensory box protein RL3899 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116254365 Common - putative GerE family transcriptional regulator RL4639 88 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116253323 Common - putative transmembrane protein RL3580 14 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116251414 Common celY putative endoglucanase/cellulase RL1648 40 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 116250056 Common - putative MarR family transcriptional regulator RL0288 14 COG1846 MarR, Transcriptional regulators Transcription 116250519 Common aglG putative alpha-glucoside transport system transmembrane component of ABC transporter RL0747 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116252375 Common - putative transmembrane protein RL2629 42 COG1289 COG1289, Predicted membrane protein Function unknown 116250891 Nonpathogen - hypothetical protein RL1119 1 None None None 116250815 Common - putative ABC transporter component RL1042 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116251702 Common - putative phosphatase RL1938 66 None None None 116254107 Common - hypothetical protein RL4374 31 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 116252291 Common - hypothetical protein RL2545 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116251519 Common - hypothetical protein RL1753 39 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 116253180 Common - putative transmembrane cation transporter RL3438 55 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 116252645 Common - putative ATP-binding component of ABC transporter RL2898 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116252344 Common rpe putative ribulose-phosphate 3-epimerase RL2598 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 116252745 Nonpathogen - hypothetical protein RL3000 2 None None None 116253266 Nonpathogen - hypothetical protein RL3524 1 None None None 116254173 Common - putative outer membrane lipoprotein omp19 RL4441 7 None None None 116251936 Common - putative phosphatase RL2179 34 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 116252252 Common cya putative adenylate cyclase 1 (atp pyrophosphate-lyase 1) (adenylyl cyclase 1) RL2506 84 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 116249927 Common polA DNA polymerase I RL0160 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 116253178 Common - hypothetical protein RL3436 43 COG2320 GrpB, Uncharacterized conserved protein Function unknown 116253675 Common - hypothetical protein RL3935 3 None None None 116249789 Common - acetyl-CoA carboxylase subunit beta RL0023 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 116254346 Common phaB putative acetoacetyl-CoA reductase RL4620 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116254385 Common - putative acetyltransferase RL4660 13 None None None 116254203 Common ade putative adenine deaminase RL4472 73 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 116254314 Common - putative LysR family transcriptional regulator RL4588 163 COG0583 LysR, Transcriptional regulator Transcription 116250501 Common flgK flagellar hook-associated protein FlgK RL0729 83 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 116252569 Common cobC putative cobalamin biosynthesis protein RL2822 205 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 116252496 Common - putative solute-binding component of ABC transporter RL2750 69 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252532 Common - short chain dehydrogenase RL2785 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251529 Nonpathogen - hypothetical protein RL1763 1 None None None 116253188 Common - putative quinoprotein glucose dehydrogenase-B RL3446 122 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 116251540 Common rplC 50S ribosomal protein L3 RL1774 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 116252408 Common - putative racemase/isomerase RL2662 120 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116250451 Common - putative two component regulator histidine kinase/response regulator transcriptional regulatory protein RL0679 212 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 116251055 Common gst2b putative glutathione S-transferase RL1288 95 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116252421 Common fabG putative 3-oxoacyl-[acyl-carrier-protein] reductase RL2674 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250232 Common - hypothetical protein RL0461 2 None None None 116254355 Common hisC histidinol-phosphate aminotransferase RL4629 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 116251105 Common - putative transmembrane protein RL1337 25 COG0730 COG0730, Predicted permeases General function prediction only 116251014 Nonpathogen - hypothetical protein RL1247 1 None None None 116251510 Common prfB peptide chain release factor 2 RL1744 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 116252507 Common - hypothetical protein RL2761 27 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116254267 Common ccmG putative thiol:disulfide interchange protein CycY precursor (cytochrome c biogenesis protein) RL4540 140 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 116251704 Common - hypothetical protein RL1940 5 None None None 116250279 Common - putative lactoylglutathione lyase RL0508 97 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116251525 Common secE preprotein translocase subunit SecE RL1759 19 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 116253691 Common - putative Arc family transcriptional regulator RL3951 8 None None None 116252764 Common - hypothetical protein RL3019 7 None None None 116250320 Common - hypothetical protein RL0548 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 116250239 Nonpathogen - hypothetical protein RL0468 1 None None None 116250263 Common frcK putative fructose transport system kinase RL0492 82 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 116250469 Common luxR putative LuxR family transcriptional regulator RL0697 30 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116250657 Common groEL chaperonin GroEL RL0883 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 116251835 Common gatC putative glutamyl-tRNA(Gln) amidotransferase subunit C RL2075 147 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 116254045 Common - putative transmembrane protein RL4309 49 COG1238 COG1238, Predicted membrane protein Function unknown 116252428 Common - putative oxidoreductase RL2681 94 COG0778 NfnB, Nitroreductase Energy production and conversion 116250158 Common metK S-adenosylmethionine synthetase RL0389 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 116254110 Common - putative solute-binding component of ABC transporter RL4377 115 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251295 Common - putative NUDIX family protein RL1529 91 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116251780 Common - hypothetical protein RL2017 4 None None None 116252936 Common - putative solute-binding component of ABC transporter RL3194 88 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 116249917 Nonpathogen - hypothetical protein smc02277 RL0150 1 None None None 116252352 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase RL2606 165 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 116251638 Common - putative pyridoxine oxidase protein RL1873 8 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 116252776 Common - putative AraC family transcriptional regulator RL3031 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116254442 Common cynT putative carbonic anhydrase RL4718 153 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 116249888 Common - putative oxidoreductase RL0122 174 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116254190 Common ocd ornithine cyclodeaminase RL4459 92 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 116253811 Common - hypothetical protein RL4074 7 None None None 116253271 Common - hypothetical protein RL3529 7 None None None 116254401 Common rpmA 50S ribosomal protein L27 RL4677 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 116254378 Common - putative transmembrane component of ABC transporter RL4653 127 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116250096 Common - undecaprenyl pyrophosphate phosphatase RL0328 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 116253438 Common hmuT hemin-binding component of ABC transporter RL3698 127 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 116252752 Common - hypothetical protein RL3007 21 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 116254122 Common - hypothetical protein RL4389 27 None None None 116250472 Common fliG flagellar motor switch protein G RL0700 122 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 116253057 Common mraZ hypothetical protein RL3316 56 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 116252103 Common - putative DJ-1/PfpI family protein RL2351 99 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 116254150 Common xynB putative beta-xylosidase RL4418 13 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 116253297 Common - putative transmembrane protein RL3555 29 COG4094 COG4094, Predicted membrane protein Function unknown 116250528 Common - hypothetical protein RL0756 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 116250460 Common cheA putative CheA chemotaxis protein RL0688 164 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 116251270 Common - hypothetical protein RL1504 63 COG1432 COG1432, Uncharacterized conserved protein Function unknown 116252122 Common pcs putative transmembrane phosphatidylcholine synthase RL2370 46 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 116253622 Common iunH putative inosine-uridine preferring nucleoside hydrolase RL3882 81 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 116251520 Common - hypothetical protein RL1754 3 None None None 116251385 Common - hypothetical protein RL1618A 76 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 116253587 Common - putative transmembrane component of ABC transporter RL3846 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250643 Common - putative ErfK/YbiS/YhnG family protein RL0870 87 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116253031 Common - putative CreA family protein RL3290 56 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 116249977 Common pilQ putative pilus subunit transmembrane protein RL0210 13 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 116253526 Common - putative MarR family transcriptional regulator RL3785 118 COG1846 MarR, Transcriptional regulators Transcription 116253745 Common cbbT transketolase RL4006 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 116251747 Common - hypothetical protein RL1984 66 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 116253288 Common - putative ATP-binding component of ABC transporter protein RL3546 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116253714 Common sqdB putative sulfoquinovosyl diacylglycerol RL3975 149 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116253488 Common - putative ATP-binding component of ABC transporter RL3747 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116251007 Common - putative lipase RL1240 27 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 116252735 Common ubiA prenyltransferase RL2990 156 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 116254145 Common - putative ATP-binding component of ABC transporter RL4413 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 116250769 Common - putative transmembrane transporter RL0996 139 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 116253994 Common cyaA putative adenylate/guanylate cyclase RL4257 81 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116250180 Common - putative rRNA methyltransferase RL0411 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 116250647 Common - putative aldo/keto reductase RL0874 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253569 Common - putative CRP/FNR family transcriptional regulator RL3828 6 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116251581 Common - putative LysR family transcriptional regulator RL1815 172 COG0583 LysR, Transcriptional regulator Transcription 116251361 Common purN phosphoribosylglycinamide formyltransferase RL1595 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 116254276 Common rpsP 30S ribosomal protein S16 RL4549 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 116252093 Common - putative transmembrane component of ABC transporter RL2340 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116254419 Common bfr putative bacterioferritin RL4695 108 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 116250607 Nonpathogen - hypothetical protein RL0835 3 None None None 116252283 Common - hypothetical protein RL2537 12 None None None 116253632 Common - putative two-component response regulator transcriptional regulatory protein RL3892 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116252741 Common - hypothetical protein RL2996 63 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 116253117 Common - hypothetical protein RL3375 5 None None None 116250804 Common thrB homoserine kinase RL1031 68 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 116254321 Common - hypothetical protein RL4595 17 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250842 Common - putative autotransporter RL1069 81 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 116253546 Common - putative transmembrane component of ABC transporter protein RL3805 149 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116254313 Common - hypothetical protein RL4587 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 116252326 Common - putative ATP-binding component of ABC transporter RL2580 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 116252221 Common - putative transmembrane protein RL2474 41 COG0730 COG0730, Predicted permeases General function prediction only 116251123 Common - hypothetical protein RL1355 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 116254335 Common - putative ATP-binding component of ABC transporter RL4609 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116250877 Common - putative transcriptional regulator RL1105 13 COG1309 AcrR, Transcriptional regulator Transcription 116252926 Common chrA putative chromate transport protein RL3184 92 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 116251775 Common - putative solute-binding component of ABC transporter RL2012 224 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116252916 Common - hypothetical protein RL3174 13 COG5485 COG5485, Predicted ester cyclase General function prediction only 116251712 Common gpt xanthine-guanine phosphoribosyltransferase RL1948 90 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 116251789 Nonpathogen - hypothetical protein RL2028 1 None None None 116254214 Common - putative ferredoxin containing dehydrogenase RL4485 155 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116250446 Common - putative response regulator transcriptional regulatory protein RL0674 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116254450 Common - hypothetical protein RL4726 8 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 116251547 Common rplP 50S ribosomal protein L16 RL1781 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 116253106 Common - hypothetical protein RL3365 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 116253154 Nonpathogen - hypothetical protein RL3412 4 None None None 116254010 Common - putative transmembrane protein RL4273 8 None None None 116253767 Common cheB putative chemotaxis two-component response regulator protein-glutamate methylesterase RL4028 206 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 116253704 Common glmM putative phosphoglucosamine mutase RL3964 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 116251752 Common nasA putative assimilatory nitrate reductase RL1989 188 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 116252556 Common - hypothetical protein RL2809 13 None None None 116252187 Common copA putative copper-containing oxidase subunit RL2434 129 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 116250348 Common - putative transmembrane protein RL0577 64 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116251543 Common rplB 50S ribosomal protein L2 RL1777 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 116254260 Common - putative acetyltransferase RL4533 121 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116250881 Common - hypothetical protein RL1109 3 None None None 116253785 Common - conserved hypothetical exported TPR repeat protein RL4046 38 None None None 116250594 Common - putative DegT family aminotransferase RL0822 195 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 116250383 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase RL0611 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 116252445 Common rpiA ribose-5-phosphate isomerase A RL2698 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 116252892 Nonpathogen - hypothetical protein RL3150 1 None None None 116249772 Common secB preprotein translocase subunit SecB RL0006 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 116251974 Common - putative endoribonuclease-L-PSP family protein RL2218 95 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116254171 Common mdh malate dehydrogenase RL4439 199 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 116252723 Common - putative transmembrane component of ABC transporter RL2977 36 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 116252473 Common - short chain dehydrogenase RL2727 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250888 Common - hypothetical protein RL1116 5 None None None 116250946 Common - putative transmembrane efflux protein RL1178 31 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 116250391 Nonpathogen - hypothetical protein RL0619 1 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 116251609 Nonpathogen - hypothetical protein RL1843 1 None None None 116251682 Common - putative exported arylsulfatase protein RL1918 74 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116249849 Common - putative LacI family transcriptional regulator RL0083 124 COG1609 PurR, Transcriptional regulators Transcription 116251392 Common rfbC putative dTDP-rhamnose-3,5-epimerase RL1626 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 116254094 Common - putative GntR family transcriptional regulator RL4361 128 COG2186 FadR, Transcriptional regulators Transcription 116254181 Common - putative LysR family transcriptional regulator RL4449 181 COG0583 LysR, Transcriptional regulator Transcription 116253531 Common - putative Rrf2 family protein RL3790 171 COG1959 COG1959, Predicted transcriptional regulator Transcription 116251348 Common - hypothetical protein RL1582 18 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 116251851 Common - putative outer membrane protein RL2091 101 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 116251965 Common cysE putative serine acetyltransferase RL2209 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 116254086 Common aroK putative shikimate kinase I RL4353 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 116251256 Nonpathogen - putative AraC family transcriptional regulator RL1490 2 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116252091 Common - putative solute-binding component of ABC transporter RL2338 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116252240 Common trpC indole-3-glycerol-phosphate synthase RL2494 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 116253074 Common - putative ABC transporter ATP-binding protein RL3333 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116250398 Nonpathogen - hypothetical protein RL0626 1 None None None 116252799 Common - putative beta-lactamase family protein RL3055 197 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 116250113 Common - hypothetical protein RL0345 4 COG3153 COG3153, Predicted acetyltransferase General function prediction only 116251087 Common - putative DNA topology modulation protein RL1319 30 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 116253835 Nonpathogen - hypothetical protein RL4098 1 None None None 116252878 Common - putative ROK family transcriptional regulator RL3136 101 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116250862 Common - putative transmembrane protein RL1090 10 None None None 116249824 Common - putative two-component regulator sensor histidine kinase transcriptional regulator RL0058 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116252983 Common - putative transmembrane protein RL3241 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 116250841 Nonpathogen - hypothetical protein RL1068 2 None None None 116250701 Common atpG F0F1 ATP synthase subunit B' RL0927 40 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 116249838 Common - putative ATP-binding component of ABC transporter RL0072 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 116252465 Common - putative transketolase RL2718 229 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 116251287 Common sodC putative superoxide dismutase RL1521 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 116252409 Common - putative transmembrane component of ABC transporter RL2663 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253246 Common - putative acetyltransferase RL3504 88 COG3153 COG3153, Predicted acetyltransferase General function prediction only 116254225 Common - uroporphyrinogen-III synthase RL4496 26 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 116250225 Common - putative transmembrane two-component sensor histidine kinase transcriptional regulator RL0456 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253208 Common - putative Xaa-Pro dipeptidase RL3466 105 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 116250551 Common dppB putative dipeptide permease component of ABC transporter RL0779 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251954 Nonpathogen - hypothetical protein RL2198 1 None None None 116250812 Common - hypothetical protein RL1039 19 COG4950 COG4950, Uncharacterized protein conserved in bacteria Function unknown 116250962 Common - putative transmembrane protein RL1194 6 None None None 116252523 Common - hypothetical protein RL2777 58 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 116253258 Common - hypothetical protein RL3516 22 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 116253516 Common - putative HlyD family secretion protein RL3775 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116252584 Common - putative component of ABC transporter RL2837 22 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 116253799 Common pykA pyruvate kinase RL4060 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 116253274 Common tdk thymidine kinase RL3532 90 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 116252824 Nonpathogen - hypothetical protein RL3080 1 None None None 116251961 Common metC cystathionine beta-lyase RL2205 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 116251428 Common - putative glycosyltransferase RL1662 193 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116251331 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase RL1565 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 116254364 Common - pyruvate carboxylase RL4638 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 116250558 Common - hypothetical protein RL0786 167 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 116252194 Common ilvI putative acetolactate synthase RL2442 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 116252298 Common def peptide deformylase RL2552 203 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 116254017 Common - hypothetical protein RL4280 31 COG5028 COG5028, Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 Intracellular trafficking and secretion 116253850 Nonpathogen - hypothetical protein RL4113 1 None None None 116250574 Common - hypothetical protein RL0803 14 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116251444 Common - hypothetical protein RL1678 121 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 116251945 Nonpathogen - hypothetical protein RL2188 1 None None None 116250931 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL1163 89 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 116250829 Common - hypothetical protein RL1056 3 None None None 116250147 Common - putative deoxyribonucleotide triphosphate pyrophosphatase RL0378 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 116249855 Common - putative oxidoreductase RL0089 95 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250918 Nonpathogen - hypothetical protein RL1148 2 None None None 116253921 Common gltX glutamyl-tRNA synthetase RL4184 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 116249829 Common - hypothetical protein RL0063 166 COG3900 COG3900, Predicted periplasmic protein Function unknown 116253131 Common - putative transmembrane protein RL3389 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252951 Nonpathogen - putative transmembrane protein RL3209 4 None None None 116252800 Common - hypothetical protein RL3056 8 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 116251802 Common - hypothetical protein RL2042 19 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 116254459 Common parB putative chromosome partitioning protein RL4735 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 116249966 Common - putative transmembrane permease component of ABC transporter RL0199 121 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 116252657 Common - putative TetR family transcriptional regulator RL2910 14 COG1309 AcrR, Transcriptional regulator Transcription 116251662 Common - hypothetical protein RL1897 8 None None None 116252560 Common - putative alcohol dehydrogenase RL2813 209 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116250726 Common - putative RNA-binding domain transcriptional regulator RL0952 143 COG2183 Tex, Transcriptional accessory protein Transcription 116251908 Common - putative transposase-related protein RL2150 107 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 116252546 Common - putative LysR family transcriptional regulator RL2799 114 COG0583 LysR, Transcriptional regulator Transcription 116250033 Common - hypothetical protein RL0265 49 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116250904 Common - putative transmembrane protein RL1132 73 COG2391 COG2391, Predicted transporter component General function prediction only 116253241 Common - hypothetical protein RL3499 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 116250371 Common - putative TetR family transcriptional regulator RL0600 29 COG1309 AcrR, Transcriptional regulator Transcription 116250314 Common - putative solute-binding component of ABC transporter RL0542 122 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 116251910 Nonpathogen - hypothetical protein RL2152 1 None None None 116251198 Common - hypothetical protein RL1432 4 None None None 116251798 Common xthA putative exodeoxyribonuclease III RL2038 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 116252790 Common - putative exported cytochrome c RL3046 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 116250567 Common - hypothetical protein RL0795A 60 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 116253670 Common - hypothetical protein RL3930 6 None None None 116253976 Common - short chain dehydrogenase RL4239 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253952 Common - putative ATP-binding component of mannitol ABC transport protein RL4215 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116253424 Common - putative transmembrane component of ABC transporter RL3683 165 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 116252276 Common - putative nitrogen fixation protein RL2530 69 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 116253080 Common - putative ribonuclease-L-PSP family protein RL3339 101 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116252077 Common - putative ROK family transcriptional regulator RL2324 129 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116252152 Common - putative MarC family transmembrane protein RL2400 155 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 116250837 Common - putative hydrolase RL1064 80 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 116250996 Common - hypothetical protein RL1229 110 COG2135 COG2135, Uncharacterized conserved protein Function unknown 116252153 Common gyrA DNA gyrase subunit A RL2401 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 116252945 Common - putative DNA stabilisation protein RL3203 10 COG3668 ParE, Plasmid stabilization system protein General function prediction only 116249833 Common - putative CBS domain protein RL0067 170 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 116251758 Common - putative LacI family transcriptional regulator RL1995 126 COG1609 PurR, Transcriptional regulators Transcription 116251025 Common - putative LysR family transcriptional regulator RL1258 163 COG0583 LysR, Transcriptional regulator Transcription 116250184 Common - putative acetyltransferase RL0415 22 COG0456 RimI, Acetyltransferases General function prediction only 116254309 Common fbpB putative iron(III)-transport system permease protein RL4583 178 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 116252235 Common - hypothetical protein RL2489 100 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 116251797 Common exoR exopolysaccharide production negative regulator RL2037 41 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 116250107 Common - putative Mg2+ chelatase family protein RL0339 194 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 116251095 Nonpathogen - hypothetical protein RL1327 1 None None None 116250908 Common - hypothetical protein RL1136 35 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 116251246 Common - hypothetical protein RL1480 12 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 116251611 Common - putative exported ErfK/YbiS/YhnG family protein RL1845 67 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116251494 Common - hypothetical protein RL1728 22 None None None 116251676 Common - hypothetical protein RL1912 22 None None None 116254277 Common rimM 16S rRNA-processing protein RL4550 98 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 116251154 Common - putative MCP chemoreceptor protein RL1386 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116250545 Common - hypothetical protein RL0773 10 None None None 116251995 Common eno putative enolase RL2239 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 116250060 Common - hypothetical protein RL0292 12 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 116250911 Common - putative transmembrane protein RL1139 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 116249866 Common - hypothetical protein RL0100 10 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 116250794 Common coxB putative cytochrome c oxidase polypeptide II precursor (cytochrome aa3 subunit 2) RL1021 139 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 116251669 Nonpathogen - hypothetical protein RL1905 4 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 116253718 Common - putative 5-formyltetrahydrofolate cyclo-ligase RL3979 180 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 116249921 Nonpathogen - hypothetical protein RL0154 1 None None None 116254270 Common ftsY putative cell division protein RL4543 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 116251366 Common ppx putative exopolyphosphatase RL1600 163 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 116252921 Common - putative cobalamin biosynthesis protein RL3179 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 116253120 Common cinI putative autoinducer synthesis protein RL3378 25 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 116253372 Common - putative glycosyltransferase RL3629 110 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116250082 Common - putative transmembrane transporter protein RL0314 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250487 Common fliL orfc; method: conceptual translation supplied by author (flil) RL0715 11 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 116251468 Common nqo5 NADH dehydrogenase subunit C RL1702 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 116253814 Common - hypothetical protein RL4077 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 116250820 Common - putative ATP-binding component of ABC transporter RL1047 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 116253020 Nonpathogen - putative transmemrbane protein RL3277 1 None None None 116249947 Common dapB dihydrodipicolinate reductase RL0180 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 116250199 Common def peptide deformylase RL0430 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 116253892 Common - putative acetyltransferase protein RL4155 88 COG3153 COG3153, Predicted acetyltransferase General function prediction only 116250137 Common pucH putative allantoinase RL0368 203 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 116250955 Common cya3 putative adenylate cyclase 3 RL1187 55 COG5616 COG5616, Predicted integral membrane protein Function unknown 116253743 Common - hypothetical protein RL4004 32 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 116251124 Common - putative transmembrane protein RL1356 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116254192 Common ubiD putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase RL4461 153 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 116253831 Nonpathogen - hypothetical protein RL4094 1 None None None 116253748 Nonpathogen - putative transmembrane protein RL4009 1 None None None 116253683 Nonpathogen - hypothetical protein RL3943 1 None None None 116250948 Common - hypothetical protein RL1180 7 None None None 116252528 Common cobS cobalamin synthase RL2781A 102 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 116253823 Common ltaE putative low-specificity l-threonine aldolase RL4086 106 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 116252594 Common - putative shikimate dehydrogenase protein RL2847 169 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 116250544 Common traA putative conjugal transfer protein RL0772 87 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 116253456 Common atcC allantoate amidohydrolase RL3716 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 116250662 Common - hypothetical protein RL0888 16 None None None 116252519 Common - hypothetical protein RL2773 13 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 161501791 Common gntZ 6-phosphogluconate dehydrogenase-like protein RL3998 159 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 116253318 Nonpathogen - hypothetical protein RL3575 2 None None None 116251827 Common lldD putative L-lactate dehydrogenase RL2067 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 116250185 Common - putative transmembrane protein RL0416 6 None None None 116252190 Nonpathogen - putative transmembrane cytochrome b562 RL2437 1 COG3038 CybB, Cytochrome B561 Energy production and conversion 116253657 Nonpathogen - putative transmembrane protein RL3917 1 None None None 116253672 Common - putative phage-related protein RL3932 4 None None None 116250193 Common - putative sigma-54 modulation protein RL0424 48 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 116252461 Common - putative iron ABC transporter permease component RL2714 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 116251820 Common - putative transmembrane protein RL2060 7 COG4872 COG4872, Predicted membrane protein Function unknown 116252502 Common - putative aromatic amino acid biosynthesis protein RL2756 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 116250141 Common mutM formamidopyrimidine-DNA glycosylase RL0372 177 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 116249784 Common - putative transmembrane protein RL0018 19 None None None 116249835 Common - putative cellulose biosynthesis protein RL0069 34 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 116250418 Common - putative aldolase RL0646 65 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 116251672 Common - putative transmembrane ion channel protein RL1908 207 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116249859 Common - putative transmembrane component of ABC transporter RL0093 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116253477 Common ureD putative urease accessory protein RL3736 79 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 116252373 Common murI glutamate racemase RL2627 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 116253536 Nonpathogen - hypothetical protein RL3795 16 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 116252974 Common - hypothetical protein RL3232 12 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 116251429 Common - putative polysaccharide export protein RL1663 114 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 116253625 Common sitB putative Fur regulated salmonella iron ABC transporter RL3885 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 116254071 Common - putative acetyltransferase RL4336 3 COG0456 RimI, Acetyltransferases General function prediction only 116251846 Common - hypothetical protein RL2086 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 116250677 Common gph putative phosphoglycolate phosphatase RL0903 77 COG0546 Gph, Predicted phosphatases General function prediction only 116251409 Common - putative two-component sensor histidine kinase RL1643 213 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 116254243 Common - putative oxidoreductase RL4516 231 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116251408 Common - putative two-component response regulator transcriptional regulatory protein RL1642 71 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116254382 Common pehA putative phosphonate monoester hydrolase RL4657 84 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116253909 Common - putative solute-binding component of ABC transporter RL4172 91 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116249775 Common mltA putative membrane-bound lytic murein transglycosylase a precursor RL0009 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 116251101 Common gst putative glutathione S-transferase RL1333 77 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116253304 Common - hypothetical protein RL3562 57 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116253336 Common - putative transmembrane transporter RL3593 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116251437 Nonpathogen - hypothetical protein RL1671 1 None None None 116252335 Nonpathogen - hyopthetical exported protein RL2589 1 None None None 116250563 Common - putative transposase RL0792 132 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 116251164 Common - hypothetical protein RL1396 4 None None None 116254026 Common - hypothetical protein RL4290 179 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 116250324 Nonpathogen - hypothetical protein RL0552 5 None None None 116250135 Common - hypothetical protein RL0366 10 COG3535 COG3535, Uncharacterized conserved protein Function unknown 116250161 Common - putative hemolysin-like protein RL0392 214 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 116253409 Common - putative serine/threonine protein phosphatase RL3668 87 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 116253230 Common - putative ATP-binding component of ABC transporter RL3488 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116253966 Common araH L-arabinose transporter permease protein RL4229 143 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116250635 Common - putative LysR family transcriptional regulator RL0862 142 COG0583 LysR, Transcriptional regulator Transcription 116253211 Nonpathogen - hypothetical protein RL3469 2 None None None 116253916 Common - putative transmembrane transporter RL4179 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253243 Common - putative transmembrane protein RL3501 32 None None None 116249957 Nonpathogen - putative transmembrane protein RL0190 1 None None None 116253700 Common - putative D-3-phosphoglycerate dehydrogenase RL3960 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 116253494 Nonpathogen - hypothetical protein RL3753 2 None None None 116253236 Common hemF coproporphyrinogen III oxidase RL3494 112 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 116251201 Common lipA putative outer membrane protein RL1435 17 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 116251593 Common - putative ATP-binding component of ABC transporter RL1827 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116251618 Common - putative enoyl-CoA hydratase family protein RL1852 146 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 116252539 Common - putative beta-mannosidase RL2792 47 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 116253414 Common ung uracil-DNA glycosylase RL3673 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 116250779 Common ribA putative riboflavin biosynthesis protein RL1006 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 116253588 Common - putative solute-binding component of ABC transporter RL3847 107 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116249794 Common - putative nucleotidyltransferase protein RL0028 215 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 116249801 Common - Sensor protein chvG (Histidine kinase sensory protein exoS). RL0035 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251567 Common - putative sulfite oxidase subunit YedZ RL1801 73 COG2717 COG2717, Predicted membrane protein Function unknown 116252608 Common - hypothetical protein RL2861 14 COG3798 COG3798, Uncharacterized protein conserved in bacteria Function unknown 116250217 Common - putative two-component sensor histidine kinase transcriptional regulator RL0448 94 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 116252962 Common - hypothetical protein RL3220 140 COG1733 COG1733, Predicted transcriptional regulators Transcription 116250423 Common - putative alcohol dehydrogenase RL0651 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 116251879 Nonpathogen - hypothetical protein RL2119 1 None None None 116252129 Common - putative solute-binding component of ABC transporter RL2377 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116251228 Common - putative oxidoreductase RL1462 153 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116253725 Common ruvC Holliday junction resolvase RL3986 196 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 116252055 Common - putative bacterial luciferase family oxidoreductase RL2299 69 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 116254068 Common - putative acetyltransferase RL4333 162 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 116250402 Common - putative ATP-binding component of ABC transporter RL0630 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116253664 Common - putative phage tail protein RL3924 4 None None None 116251163 Common - putative TerC family transporter RL1395 98 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 116252621 Common - hypothetical protein RL2874 25 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 116251430 Common exoP putative transmembrane succinoglycan biosynthesis transport protein RL1664 78 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 116250075 Common - putative LysR family transcriptional regulator RL0307 167 COG0583 LysR, Transcriptional regulator Transcription 116252786 Common ctaE2 putative transmembrane cytochrome oxidase subunit RL3042 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 116251884 Nonpathogen - putative transmembrane protein RL2124 1 None None None 116250361 Common - putative short-chain dehydrogenase/reductase RL0590 204 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116252767 Nonpathogen - putative nodulation protein RL3022 1 None None None 116253556 Common - putative glycosyl hydrolase RL3815 42 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 116253400 Common prsD putative transmembrane ABC transporter component RL3658 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 116253984 Common - putative LacI family transcriptional regulatory protein RL4247 126 COG1609 PurR, Transcriptional regulators Transcription 116251731 Common - putative AraC family transcriptional regulator RL1967 157 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 116252756 Common - putative transmembrane transport protein RL3011 83 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252509 Common - hypothetical protein RL2763 13 COG5649 COG5649, Uncharacterized conserved protein Function unknown 116252468 Common rbsB putative D-ribose-binding protein component of ABC transporter RL2721 95 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250332 Common - putative AraC family transcriptional regulator RL0561 47 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116252199 Common - putative LacI family transcriptional regulator RL2447 125 COG1609 PurR, Transcriptional regulators Transcription 116254208 Common - putative LysR family transcriptional regulator RL4478 141 COG0583 LysR, Transcriptional regulator Transcription 116251890 Common - hypothetical protein RL2130 4 None None None 116252037 Common ntrY two component regulator response regulator putative nitrogen regulation protein RL2281 219 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 116254362 Common - putative ATP-binding component of ABC transporter RL4636 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116252530 Nonpathogen - putative transmembrane protein RL2783 1 COG2510 COG2510, Predicted membrane protein Function unknown 116250698 Common atpI putative ATP synthase protein I RL0924 26 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 116252161 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II RL2409 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116252739 Common - putative transmembrane component of ABC transporter RL2994 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116250623 Common - putative TetR family transcriptional regulator RL0850 23 COG1309 AcrR, Transcriptional regulator Transcription 116252996 Common hflC putative transmembrane serine protease RL3253 137 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 116253383 Nonpathogen - putative transmembrane protein RL3641 1 None None None 116254199 Common - putative ATP-binding component of ABC transporter RL4468 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116252301 Common lipB lipoyltransferase RL2555 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 116253504 Common - putative rRNA methyltransferase RL3763 173 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 116252322 Common sufA putative HesB nitrogen fixation family protein RL2576 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 116253946 Common - putative glyoxalase protein RL4209 30 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 116252570 Common cobB cobyrinic acid a,c-diamide synthase RL2823 137 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 116251631 Common - putative maleylacetoacetate isomerase RL1866 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116249993 Common - putative transmembrane permease component of ABC transporter RL0226 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250715 Common - putative peptidase RL0941 172 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116250739 Common - putative Acyl-CoA dehydrogenase RL0965 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 116253540 Common - putative hydroxypyruvate isomerase RL3799 89 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 116252833 Common - putative methyltransferase RL3090 103 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116250928 Common - putative cytochrome c protein RL1160 57 COG2863 COG2863, Cytochrome c553 Energy production and conversion 116250011 Common - putative dTDP-4-dehydrorhamnose 3,5-epimerase protein RL0243 163 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 116251489 Common dnaE DNA polymerase III subunit alpha RL1723 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 116253856 Common glgX putative glycogen debranching enzyme RL4119 128 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 116253461 Common - putative transmembrane component of ABC transporter RL3721 84 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 116251715 Common wrbA TrpR binding protein WrbA RL1951 116 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 116251766 Common - putative peroxidase RL2003 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116250682 Common - putative solute-binding component of ABC transporter RL0908 85 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252166 Nonpathogen - hypothetical protein RL2414 1 None None None 116252034 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2278 135 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116254201 Common hutH putative histidine ammonia-lyase RL4470 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 116254426 Common citE putative citrate lyase beta chain RL4702 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 116253445 Common - two-component response regulator RL3705 114 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 116253327 Common allA ureidoglycolate hydrolase RL3584 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 116253206 Common - hypothetical protein RL3464 95 COG1565 COG1565, Uncharacterized conserved protein Function unknown 116252901 Common ampC beta-lactamase RL3159 112 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 116250967 Common - putative transmembrane protein RL1200 166 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 116251113 Common - putative LysE family efflux protein RL1345 120 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116253757 Common - putative ATP-binding component of ABC transporter RL4018 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116250686 Common - putative GGDEF/EAL sensory box protein RL0912 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116249864 Common - putative mannitol dehydrogenase RL0098 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 116250992 Nonpathogen - hypothetical protein RL1225 1 None None None 116252477 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2731 189 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 116253900 Common - hypothetical protein RL4163 48 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 116252815 Common ftsZ cell division protein FtsZ RL3071 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 116252827 Common - putative TetR family transcriptional regulator RL3084 128 COG1309 AcrR, Transcriptional regulator Transcription 116250611 Nonpathogen - hypothetical protein RL0838 2 None None None 116251036 Common - hypothetical protein RL1269 18 COG3668 ParE, Plasmid stabilization system protein General function prediction only 116250950 Nonpathogen - hypothetical protein RL1182 1 None None None 116252816 Common - hypothetical protein RL3072 3 None None None 116250171 Common trpS tryptophanyl-tRNA synthetase RL0402 234 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250000 Common purU formyltetrahydrofolate deformylase RL0233 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 116253496 Nonpathogen - putative transmembrane protein RL3755 1 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 116252998 Common folA putative dihydrofolate reductase RL3255 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116252701 Nonpathogen - hypothetical protein RL2954 1 None None None 116252480 Common - hypothetical protein RL2734 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116250130 Common - putative LysR family transcriptional regulator RL0361 186 COG0583 LysR, Transcriptional regulator Transcription 116251761 Common - putative transmembrane component of ABC transporter RL1998 97 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116252453 Common - hypothetical protein RL2706 41 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 116251268 Common mosA dihydrodipicolinate synthase RL1502 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116250780 Common aroC chorismate synthase RL1007 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 116252068 Nonpathogen - hypothetical protein RL2315 3 None None None 116253782 Common - hypothetical protein RL4043 33 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 116250449 Common - putative GerE family transcriptional regulator RL0677 95 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116251312 Common purF amidophosphoribosyltransferase RL1546 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 116250358 Common - putative transmembrane protein RL0587 113 COG0730 COG0730, Predicted permeases General function prediction only 116250458 Common cheX putative chemotaxis related CheX protein RL0686 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 116251108 Common sodB putative superoxide dismutase RL1340 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 116252210 Common - putative transmembrane protein RL2459 24 COG3821 COG3821, Predicted membrane protein Function unknown 116250018 Common - hypothetical protein RL0250 30 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 116250512 Common - putative transmembrane protein RL0740 11 None None None 116253893 Common - putative lysine/ornithine decarboxylase RL4156 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 116252357 Nonpathogen - hypothetical protein RL2611 1 None None None 116250298 Nonpathogen - hypothetical protein RL0527 1 None None None 116253840 Common - hypothetical protein RL4103 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 116251482 Common - putative beta-lactamase family protein RL1716 157 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 116253134 Nonpathogen - hypothetical protein RL3392 1 None None None 116253137 Common - putative transmembrane protein RL3395 97 COG2962 RarD, Predicted permeases General function prediction only 116250397 Common - hypothetical protein RL0625 3 None None None 116252483 Common ohr putative organic hydroperoxide resistance protein RL2737 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116251459 Common - hypothetical protein RL1693 27 None None None 116254087 Common xerD site-specific tyrosine recombinase XerD RL4354 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116251078 Common - putative ATP-binding component of ABC transporter RL1310 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116250085 Common - hypothetical protein RL0317 63 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 116250971 Common - putative LysR family transcriptional regulator RL1204 153 COG0583 LysR, Transcriptional regulator Transcription 116253953 Common mtlG putative mannitol transmembrane permease component of ABC transporter RL4216 168 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116251277 Common rnc ribonuclease III RL1511 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 116253899 Common eda keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase RL4162 124 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 116252431 Common - hypothetical protein RL2684 9 None None None 116252204 Common - putative transposase-related protein RL2453 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 116254395 Nonpathogen - hypothetical protein RL4670 1 None None None 116252628 Common - putative two component response regulator transcriptional regulatory protein RL2881 212 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 116253617 Common - putative LacI family transcriptional regulator RL3877 126 COG1609 PurR, Transcriptional regulators Transcription 116253142 Common - hypothetical protein RL3400 10 None None None 116253308 Common - putative AraC family transcriptional regulator RL3566 144 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 116251586 Common - putative HTH-type transcriptional regulator RL1820 127 COG1609 PurR, Transcriptional regulators Transcription 116249939 Common - putative ATP-binding component of phosphate uptake ABC transporter RL0172 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 116251343 Common - putative GGDEF family sensory box protein RL1577 165 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116252610 Common - hypothetical protein RL2863 30 COG4907 COG4907, Predicted membrane protein Function unknown 116252395 Common folB putative dihydroneopterin aldolase RL2649 77 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 116253800 Common - hypothetical protein RL4061 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 116250650 Common - hypothetical protein RL0876 6 None None None 116254116 Common - putative AsnC family transcriptional regulator RL4383 126 COG1522 Lrp, Transcriptional regulators Transcription 116251982 Common cdsA putative phosphatidate cytidylyltransferase RL2226 214 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 116253175 Common str putative streptomycin 3''-kinase RL3433 29 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 116252853 Common - putative transcriptional regulator RL3112 170 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116251254 Common - hypothetical protein RL1488 10 None None None 116251707 Common - hypothetical protein RL1943 16 None None None 116253000 Common - hypothetical protein RL3257 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 116251452 Common - putative cytochrome P450 RL1686 81 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 116250301 Nonpathogen - hypothetical protein RL0530 1 None None None 116251679 Common - hypothetical protein RL1915 10 None None None 116250754 Common - hypothetical protein RL0980 56 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 116250274 Common otsA putative trehalose-6-phosphate synthase,glycosyltransferase RL0503 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 116253847 Common - hypothetical protein RL4110 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 116253079 Common ilvG acetolactate synthase 2 catalytic subunit RL3338 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 116253186 Common - putative transmembrane protein RL3444 44 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 116252902 Common - hypothetical protein RL3160 17 None None None 116251744 Common - putative short-chain dehydrogenase/oxiroreductase RL1981 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116252956 Common - putative transmembrane NADH dehydrogenase RL3214 192 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 116250024 Common - putative transcriptional regulator RL0256 86 COG1396 HipB, Predicted transcriptional regulators Transcription 116253776 Nonpathogen - hypothetical protein RL4037 3 None None None 116251865 Common - putative NADH-ubiquinone oxidoreductase subunit RL2104 36 None None None 116251903 Nonpathogen - hypothetical protein RL2145 1 None None None 116249808 Common hisF imidazole glycerol phosphate synthase subunit HisF RL0042 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 116250997 Nonpathogen - hypothetical protein RL1230 1 None None None 116251656 Common - putative transmembrane protein RL1891 49 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 116252676 Nonpathogen - hypothetical protein RL2929 1 None None None 116251373 Common - putative TetR family transcriptional regulator RL1607 99 COG1309 AcrR, Transcriptional regulator Transcription 116253935 Common - putative two-component response regulator transcriptional regulatory protein RL4198 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116250201 Common - putative plasmid stability protein RL0432 60 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 116251557 Common rpsE 30S ribosomal protein S5 RL1791 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 116253881 Common - putative oxidoreductase/dehydrogenase RL4144 227 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 116251534 Common - hypothetical protein RL1768 6 None None None 116252097 Common - hypothetical protein RL2344 5 None None None 116252660 Common - putative GntR family transcriptional regulator RL2913 132 COG1802 GntR, Transcriptional regulators Transcription 116252890 Common - putative adenylate/guanylate cyclase RL3149 77 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116251149 Common - hypothetical protein RL1381 6 None None None 116254001 Common - hypothetical protein RL4264 84 COG2081 COG2081, Predicted flavoproteins General function prediction only 116252618 Common - putative transmembrane efflux pump RL2871 106 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116253711 Common exbD putative biopolymer transport protein RL3972 129 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 116249884 Common fabI enoyl-(acyl carrier protein) reductase RL0118 209 COG0623 FabI, Enoyl- acyl-carrier-protein 116251145 Common mrpF putative monovalent cation/H+ antiporter subunit F RL1377 30 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 116253354 Common - putative two-component response regulator transcriptional regulatory protein RL3611 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 116250626 Common - hypothetical protein RL0853 11 COG5403 COG5403, Uncharacterized conserved protein Function unknown 116253045 Common galE putative UDP-glucose 4-epimerase RL3304 213 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116250613 Nonpathogen - hypothetical protein RL0840 1 None None None 116251983 Common ecfE putative transmembrane protease RL2227 218 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 116252787 Common ctaE1 putative cytochrome c oxidase subunit III RL3043 8 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 116253059 Common - putative N-methyl-L-tryptophan oxidase RL3318 17 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116251522 Common rLmB putative 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB RL1756 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 116253436 Common hmuP Hemin uptake protein RL3696 7 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 116251931 Nonpathogen - hypothetical protein RL2174 2 None None None 116253826 Common ibpA putative heat shock protein A RL4089 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 116251098 Common - putative transmembrane efflux pump protein RL1330 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252411 Common - hypothetical protein RL2665 21 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116254291 Common amtB putative transmembrane ammonium transporter RL4564 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 116253389 Common - putative polysaccharide polymerisation protein RL3647 20 COG5039 COG5039, Exopolysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 116252778 Common - hypothetical protein RL3033 16 None None None 116251791 Nonpathogen - hypothetical protein RL2031 1 None None None 116249979 Common cpaA putative pilus assembly protein RL0212 27 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116253524 Common - putative transmembrane efflux/multidrug resistance protein RL3783 228 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116254440 Common - hypothetical protein RL4716 99 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 116251121 Nonpathogen - hypothetical protein RL1353 1 None None None 116251139 Nonpathogen - putative transmembrane protein RL1371 1 None None None 116253366 Common - hypothetical protein RL3623 88 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116252155 Common coaD phosphopantetheine adenylyltransferase RL2403 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 116250582 Nonpathogen - hypothetical protein RL0810A 1 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 116252359 Common - putative transmembrane protein RL2613 15 None None None 116253534 Common - putative LacI family transcriptional regulator RL3793 126 COG1609 PurR, Transcriptional regulators Transcription 116253732 Common - putative damage inducible protein RL3993 34 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 116249842 Common - hypothetical protein RL0076 2 None None None 116253139 Common neo putative aminoglycoside 3'-phosphotransferase RL3397 20 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 116250466 Common - hypothetical protein RL0694 3 None None None 116250645 Common - hypothetical protein RL0872 2 None None None 116250208 Common - hypothetical protein RL0439 13 None None None 116251583 Common - putative lipase/esterase RL1817 124 COG0657 Aes, Esterase/lipase Lipid metabolism 116252987 Common ilvI acetolactate synthase 3 catalytic subunit RL3245 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 116250538 Common - probable putrescine transport system permease protein RL0766 216 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116252606 Common greA transcription elongation factor regulatory protein RL2859 119 COG0782 GreA, Transcription elongation factor Transcription 116252780 Common tynA tyramine oxidase RL3036 22 COG3733 TynA, Cu2+-containing amine oxidase Secondary metabolites biosynthesis, transport, and catabolism 116251905 Nonpathogen - hypothetical protein RL2147 1 None None None 116253395 Common exoM putative succinoglycan biosynthesis protein RL3653 24 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116250510 Common - hypothetical protein RL0738 11 None None None 116252120 Common - putative GntR family transcriptional regulator RL2368 110 COG1802 GntR, Transcriptional regulators Transcription 116253797 Common - hypothetical protein RL4058 13 None None None 116250094 Common - putative 4Fe-4S ferredoxin protein RL0326 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 116250641 Common - lipid A oxidase RL0868 2 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 116250982 Nonpathogen - putative transmembrane protein RL1215 2 None None None 116254408 Common nadD nicotinic acid mononucleotide adenyltransferase RL4684 178 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 116252433 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase RL2686 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 116253585 Common - putative ATP-binding component of ABC transporter RL3844 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116254417 Common - putative polysaccharide deacetylase protein RL4693 56 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 116252630 Common - hypothetical protein RL2883 3 None None None 116253630 Common - putative transmembrane protein RL3890 24 None None None 116254131 Common - putative FMN reductase RL4398 98 COG0431 COG0431, Predicted flavoprotein General function prediction only 116252095 Common - putative component of ABC transporter RL2342 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251867 Nonpathogen - hypothetical protein RL2105A 1 None None None 116252274 Common thrS threonyl-tRNA synthetase RL2528 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116253598 Common - putative mandelate racemase/muconate lactonising family protein RL3858 114 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116249806 Common coaA pantothenate kinase RL0040 80 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 116252637 Nonpathogen - hypothetical protein RL2890 1 None None None 116253150 Common dnaG DNA primase RL3408 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 116254058 Common argH argininosuccinate lyase RL4323 234 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 116253712 Common tolQ putative TolQ protein uptake system component RL3973 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 116250609 Nonpathogen - hypothetical protein RL0836A 1 None None None 116251536 Common rpsG 30S ribosomal protein S7 RL1770 241 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 116250767 Common - putative hydroxypyruvate reductase RL0994 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 116251383 Common - putative transmemrbane protein RL1617 13 None None None 116252061 Nonpathogen - hypothetical protein RL2305 1 None None None 116254168 Common sucD succinyl-CoA synthetase subunit alpha RL4436 207 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 116250026 Common - putative haloacid dehydrogenase hydrolase RL0258 71 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116254254 Common - putative protein phosphatase RL4527 128 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 116250802 Common - putative transmembrane cytochrome oxidase biogenesis protein RL1029 54 COG3346 COG3346, Uncharacterized conserved protein Function unknown 116252105 Common - putative LysR family transcriptional regulator RL2353 170 COG0583 LysR, Transcriptional regulator Transcription 116253295 Common engA GTP-binding protein EngA RL3553 235 COG1160 COG1160, Predicted GTPases General function prediction only 116251020 Common - putative LysR family transcriptional regulator RL1253 169 COG0583 LysR, Transcriptional regulator Transcription 116250508 Common fliR flagellar biosynthesis protein FliR RL0736 116 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 116250035 Common rpmI 50S ribosomal protein L35 RL0267 38 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 116251693 Nonpathogen - hypothetical protein RL1929 2 None None None 116251640 Nonpathogen - putative transmembrane protein RL1875 1 None None None 116254460 Common parA putative chromosome partitioning protein RL4736 210 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 116252063 Common - hypothetical protein RL2307 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 116250875 Common - hypothetical protein RL1103 12 COG4328 COG4328, Uncharacterized protein conserved in bacteria Function unknown 116254449 Common - heat shock protein HtpX RL4725 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 116252075 Common - hypothetical protein RL2322 20 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 116253594 Common - putative protein involved in invasion RL3853 33 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 116253119 Common bisR putative AHL-dependent transcriptional regulator RL3377 46 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116253763 Common - putative transmembrane protein RL4024 28 None None None 116252324 Common sufS putative aminotransferase involved in iron-sulfur cluster biogenesis RL2578 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 116253727 Common - hypothetical protein RL3988 16 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 116250377 Common - enoyl-CoA hydratase RL0606 164 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 116251394 Nonpathogen - hypothetical protein RL1628 1 None None None 116254022 Common ubiG 3-demethylubiquinone-9 3-methyltransferase RL4286 157 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116254175 Common sdhB succinate dehydrogenase iron-sulfur subunit RL4443 194 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 116252725 Common - putative riboflavin biosynthesis protein RL2979 23 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116254430 Common ilvA putative threonine dehydratase biosynthetic RL4706 178 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 116252361 Common - putative glutaredoxin RL2615 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 116250353 Common - putative ATP-dependent helicase RL0582 201 COG1201 Lhr, Lhr-like helicases General function prediction only 116252758 Common tyrS putative tyrosyl-tRNA synthetase RL3013 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250058 Common - hypothetical protein RL0290 111 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116252943 Nonpathogen - putative PIN/PilT family protein RL3201 1 None None None 116249787 Common trpB tryptophan synthase subunit beta RL0021 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 116251934 Nonpathogen - hypothetical protein RL2177 1 None None None 116250835 Common thrC threonine synthase RL1062 158 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 116251633 Common - putative universal stress related protein RL1868 40 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116254109 Common - putative transmembrane component of ABC transporter RL4376 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250517 Common aglE abc transporter, substrate binding protein (agr_c_1045p) RL0745 42 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253268 Common - hypothetical protein RL3526 55 COG2862 COG2862, Predicted membrane protein Function unknown 116253778 Common - putative polar organelle development protein RL4039 103 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 116252223 Common tmk putative thymidylate kinase (dtmp kinase) RL2476 235 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 116253036 Common recN putative DNA repair protein RL3295 209 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 116252247 Common - putative LysR family transcriptional regulator RL2501 188 COG0583 LysR, Transcriptional regulator Transcription 116250118 Common - hypothetical protein RL0350 25 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116254439 Common asd aspartate-semialdehyde dehydrogenase RL4715 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 116252287 Common - putative penicillin-binding protein/D-alanyl-D-alanine carboxypeptidase RL2541 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116251042 Common - putative GGDEF/EAL sensory box protein RL1275 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 116249971 Common - hypothetical protein RL0204 52 COG3577 COG3577, Predicted aspartyl protease General function prediction only 116253642 Common xfp putative phosphoketolase RL3902 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 116250367 Common - putative MarR family transcriptional regulator RL0596 29 COG1846 MarR, Transcriptional regulators Transcription 116251750 Nonpathogen - hypothetical protein RL1987 1 None None None 116251135 Common - putative hemolysin-related transmembrane protein RL1367 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 116253286 Common - putative transmembrane component of ABC transporter protein RL3544 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251505 Common pyrB aspartate carbamoyltransferase catalytic subunit RL1739 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 116252743 Common - putative hydrolase RL2998 12 COG0388 COG0388, Predicted amidohydrolase General function prediction only 116251315 Common - putative transmembrane efflux protein RL1549 121 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116254328 Common nagA putative N-acetylglucosamine-6-phosphate deacetylase RL4602 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 116250717 Common glyQ glycyl-tRNA synthetase subunit alpha RL0943 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 116254307 Common - hypothetical protein RL4581 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 116251941 Nonpathogen - hypothetical protein RL2184 6 None None None 116252084 Common attS putative attachment to host cell protein RL2331 43 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 116251512 Common - putative transmembrane component of ABC transporter RL1746 135 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116254105 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase RL4372 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 116254043 Common - putative cation efflux transmembrane transport protein RL4307 193 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 116251333 Common - putative outer membrane protein involved in envelope biosynthesis RL1567 115 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 116250526 Common ordL putative oxidoreductase RL0754 132 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116251000 Common - putative TetR family transcriptional regulator RL1233 30 COG1309 AcrR, Transcriptional regulator Transcription 116251527 Common rplK 50S ribosomal protein L11 RL1761 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 116252848 Common bgaB putative beta-galactosidase RL3107 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 116253353 Common - hypothetical protein RL3610 111 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 116251804 Common scpA putative chromosome segregation and condensation protein A RL2044 129 COG1354 COG1354, Uncharacterized conserved protein Function unknown 116250832 Common - putative transmembrane sensory box GGDEF/EAL domain protein RL1059 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116251057 Common - putative sensory box GGDEF/EAL domain protein RL1290 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116252342 Common - putative TfoX family protein RL2596 26 COG3070 TfoX, Regulator of competence-specific genes Transcription 116254138 Common atpC F0F1 ATP synthase subunit epsilon RL4405 164 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 116253479 Common - putative ATP-binding component of ABC transporter RL3738 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 116253770 Common - putative sensory transducer methyl-accepting chemotaxis protein RL4031 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116252176 Common - putative acetyltransferase RL2424 15 COG3393 COG3393, Predicted acetyltransferase General function prediction only 116250898 Common - hypothetical protein RL1126 42 COG5361 COG5361, Uncharacterized conserved protein Function unknown 116252046 Common cysI putative sulfite reductase RL2290 164 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 116252253 Nonpathogen - hypothetical protein RL2507 4 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 116251616 Common - putative isochorismatase family protein RL1850 111 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116253232 Common - putative ATP-binding component of ABC transporter RL3490 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116251290 Common - hypothetical protein RL1524 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 116253210 Common prs ribose-phosphate pyrophosphokinase RL3468 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 116253014 Common cya3 putative transmembrane adenylate/guanylate cyclase RL3271 52 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116253029 Common - putative Sco copper chaperone family protein RL3288 106 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 116254125 Common fdsB putative NAD-dependent formate dehydrogenase beta subunit RL4392 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 116253050 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase RL3309 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 116253655 Nonpathogen - hypothetical protein RL3915 1 None None None 116250145 Common - putative L-lysine dehydrogenase RL0376 31 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 116253649 Common - putative ATP-binding component of ABC transporter RL3909 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116254038 Common - putative oxidoreductase RL4302 207 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116251426 Common - putative transmembrane protein RL1660 12 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 116252498 Common - putative OmpA family protein RL2752 96 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 116251833 Common ruvX putative Holliday junction resolvase RL2073 161 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 116249792 Common - putative ATP-dependent UvrD family DNA helicase RL0026 227 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 116251573 Common - recombination factor protein RarA RL1807 222 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 116252803 Nonpathogen - hypothetical protein RL3059 7 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 116252005 Common - lipoyl synthase RL2249 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 116252138 Common mfd putative transcription-repair coupling factor RL2386 218 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 116250265 Common - putative transmembrane sensory box GGDEF domain protein RL0494 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116250416 Common rbtD putative ribitol 2-dehydrogenase RL0644 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116252118 Common - hypothetical protein RL2366 208 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 116249960 Common - hypothetical protein RL0193 50 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 116250388 Common infA translation initiation factor IF-1 RL0616 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 116251629 Common hmgA homogentisate 1,2-dioxygenase RL1864 51 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 116252863 Common - putative acetyltransferase RL3121 74 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116254224 Common hemC porphobilinogen deaminase RL4495 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 116252521 Common ropA putative outer membrane protein RL2775 13 None None None 116250045 Common - putative oxidoreductase RL0277 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253334 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL3591 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116250187 Common - putative peptidase RL0418 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116253099 Common - putative transmembrane component of ABC transporter RL3358 180 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116254412 Common mopB putative molybdenum-pterin binding protein RL4688 96 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 116250004 Common - putative exopolysaccharide related transporter RL0237 67 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 116252380 Common - putative AraC family transcriptional regulator RL2634 143 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 116251359 Common nudF putative ADP-ribose pyrophosphatase RL1593 161 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 116249799 Common - PTS system, mannose-specific IIAB component (EIIAB-Man) (Mannose-permease IIAB component) (Phosphotransferase enzyme II, AB component) (EIII-Man). RL0033 97 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 116250226 Nonpathogen - hypothetical protein RL0456A 1 None None None 116251912 Nonpathogen - hypothetical protein RL2154 1 None None None 116253248 Common - putative MutT/NUDIX family protein RL3506 52 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116250438 Common - putative exported lipase RL0666 8 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116251811 Common pcm protein-L-isoaspartate O-methyltransferase RL2051 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 116252192 Nonpathogen - putative peroxiredoxin RL2440 5 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116251196 Common - hypothetical protein RL1430 12 None None None 116249868 Common gabT 4-aminobutyrate aminotransferase RL0102 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 116251027 Common cysN putative sulfate adenylyltransferase RL1260 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 116254227 Common - putative transmembrane protein RL4498 26 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 116250316 Common - putative transmembrane component of ABC transporter RL0544 221 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 116253156 Common tetA putative tetracycline resistance protein RL3414 230 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250817 Common - putative transmembrane component of ABC transporter RL1044 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116250126 Common coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase RL0357 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 116250491 Common flaB putative flagellin B RL0719 108 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116250706 Common - hypothetical protein RL0932 15 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251432 Common cox15 putative transmembrane heme A synthase RL1666 52 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 116253790 Common tdcB putative threonine dehydratase catabolic RL4051 217 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 116252586 Common - putative LysR family transcriptional regulator RL2839 192 COG0583 LysR, Transcriptional regulator Transcription 116249777 Common - putative transcriptional regulator RL0011 27 COG1396 HipB, Predicted transcriptional regulators Transcription 116251739 Nonpathogen - hypothetical protein RL1975 1 None None None 116254039 Common - putative TetR family transcriptional regulator RL4303 100 COG1309 AcrR, Transcriptional regulator Transcription 116253575 Common - putative ErfK/YbiS/YhnG oxidoreductase RL3834 83 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116250886 Nonpathogen - hypothetical protein RL1114 1 None None None 116251664 Common - putative transposase related protein RL1899 48 None None None 116253422 Common - putative ATP-binding component of ABC transporter RL3681 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116254428 Common - putative glyoxalase family protein RL4704 67 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 116249870 Common - putative ribonuclease RL0104 102 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 116251080 Common - hypothetical protein RL1312 8 None None None 116254140 Common atpG F0F1 ATP synthase subunit gamma RL4408 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 116249969 Common deoC putative deoxyribose-phosphate aldolase RL0202 125 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 116252581 Common cya putative adenylate/guanylate cyclase RL2834 82 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116250109 Common - putative LysE family transport protein RL0341 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116253194 Common - hypothetical protein RL3452 132 COG1733 COG1733, Predicted transcriptional regulators Transcription 116250902 Nonpathogen - hypothetical protein RL1130 3 COG0645 COG0645, Predicted kinase General function prediction only 116249877 Common - putative transmembrane protein RL0111 18 COG3619 COG3619, Predicted membrane protein Function unknown 116253576 Nonpathogen - hypothetical protein RL3835 4 None None None 116250708 Common moaB putative molybdenum cofactor biosynthesis protein RL0934 174 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 116250182 Common - putative MutT/NUDIX family ADP compounds hydrolase RL0413 36 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 116250994 Common - hypothetical protein RL1227 10 None None None 116253571 Nonpathogen - putative transmembrane protein RL3830 1 None None None 116252466 Common - putative ferredoxin RL2719 223 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 116252544 Common - putative LacI family transcriptional regulator RL2797 122 COG1609 PurR, Transcriptional regulators Transcription 116250246 Nonpathogen - hypothetical protein RL0475 1 None None None 116252643 Common - putative transmembrane transporter RL2896 177 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116252958 Common asr putative aspartate racemase RL3216 80 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 116253992 Common exsC putative 6-pyruvoyl tetrahydropterin synthase protein RL4255 105 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 116250409 Common - putative transmembrane component of ABC transporter RL0637 177 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116252914 Nonpathogen - hypothetical protein RL3172 1 None None None 116252684 Nonpathogen - putative transmembrane protein RL2937 1 None None None 116252189 Common - putative transmembrane protein RL2436 3 None None None 116252558 Common - hypothetical protein RL2811 5 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 116253183 Common - hypothetical protein RL3441 35 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 116250124 Common - putative pirin-like protein RL0355 148 COG1741 COG1741, Pirin-related protein General function prediction only 116251956 Common - hypothetical protein RL2200 4 None None None 116251899 Nonpathogen - hypothetical protein RL2140 1 None None None 116252149 Common - putative acetyltransferase RL2397 26 COG0456 RimI, Acetyltransferases General function prediction only 116251445 Common cysD O-acetylhomoserine aminocarboxypropyltransferase RL1679 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 116250340 Common - putative two-component response regulator RL0569 171 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116252928 Nonpathogen - putative transmembrane protein RL3186 1 None None None 116252410 Common lpxH putative UDP-2,3-diacylglucosamine hydrolase RL2664 65 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 116253932 Common - putative transmembrane protein RL4195 9 COG5487 COG5487, Small integral membrane protein Function unknown 116251545 Common rplV 50S ribosomal protein L22 RL1779 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 116254216 Common - dihydropyrimidinase RL4487 205 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 116254298 Common - hypothetical protein RL4572 31 COG3760 COG3760, Uncharacterized conserved protein Function unknown 116251173 Common - putative glyoxalase RL1405 60 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 116253281 Common - putative sensory box HD domain protein RL3539 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 116252894 Common - putative transcriptional regulator RL3152 13 COG3832 COG3832, Uncharacterized conserved protein Function unknown 161501793 Common acpXL acyl carrier protein RL2817 101 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116251450 Common - putative transmembrane component of ABC transporter RL1684 225 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 116254352 Common - hypothetical protein RL4626 8 COG5255 COG5255, Uncharacterized protein conserved in bacteria Function unknown 116252876 Common ugpA putative SN-glycerol-3-phosphate transport system permease protein RL3134 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250280 Common - putative component of ABC transporter RL0509 122 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 116252985 Common - putative aldo-keto reductase family protein RL3243 201 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 116252023 Common - putative arylsulfatase RL2267 83 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116252881 Common - putative methyltransferase RL3140 54 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 116251920 Nonpathogen - hypothetical protein RL2162 1 None None None 116253470 Common - putative transmembrane GGDEF sensory box protein RL3729 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116254149 Common - putative solute-binding component of ABC transporter RL4417 135 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116250381 Nonpathogen - hypothetical protein RL0610 1 None None None 116249768 Common - Maf-like protein RL0002 183 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 116252948 Common - putative TetR family transcriptional regulator RL3206 17 COG1309 AcrR, Transcriptional regulator Transcription 116251503 Common - hypothetical protein RL1737 168 COG0344 COG0344, Predicted membrane protein Function unknown 116251009 Common - hypothetical protein RL1242 8 None None None 116250241 Nonpathogen - hypothetical protein RL0470 1 None None None 116251301 Common - hypothetical protein RL1535 32 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 116250652 Common hisZ ATP phosphoribosyltransferase regulatory subunit RL0878 86 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 116253108 Common hyuE putative hydantoin racemase RL3367 41 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 116251721 Common - putative short-chain dehydrogenase/oxidoreductase RL1957 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253922 Common lysS putative lysyl-tRNA synthetase RL4185 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 116251208 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL1442 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116252809 Common - hypothetical protein RL3065 2 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 116254316 Common aceC putative GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferse RL4590 51 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116250051 Common - putative NAD(P)H oxidoreductase RL0283 74 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 116253878 Common - putative TRAP family transmembrane transporter protein RL4141 135 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 116254265 Common ccmB putative cytochrome c binding export protein RL4538 83 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 116253706 Common tilS putative tRNA(Ile)-lysidine synthase RL3966 187 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 116249895 Common - putative transmembrane transport protein RL0129 105 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116251279 Common - putative CRP/FNR family transcriptional regulator RL1513 97 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116251439 Common rplM 50S ribosomal protein L13 RL1673 235 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 116250115 Common prfC putative peptide chain release factor (RF-3) RL0347 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 116252419 Common rnhA putative ribonuclease HI RL2672 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 116251457 Common hu putative DNA-binding protein HU RL1691 197 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 116250743 Common rumA putative 23S rRNA (uracil-5-)-methyltransferase RL0969 192 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 116254113 Nonpathogen - hypothetical protein RL4380 1 None None None 116249904 Common - putative transcriptional regulator RL0137 69 COG2378 COG2378, Predicted transcriptional regulator Transcription 116250897 Common - putative carboxylesterase RL1125 58 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 116253251 Common - putative ECF sigma factor RL3509 82 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116250864 Common - hypothetical protein RL1092 31 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 116249810 Nonpathogen - hypothetical protein RL0044 2 None None None 116251289 Common - hypothetical protein RL1523 15 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 116252567 Nonpathogen - hypothetical protein RL2820 1 None None None 116250474 Common fliM putative flagella motor switch protein RL0702 11 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 116252238 Common ppiD putative peptidyl-prolyl cis-trans isomerase D RL2492 122 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 116253157 Common - putative oxidoreductase RL3415 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253803 Common - hypothetical protein RL4065 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 116254073 Common hisC histidinol-phosphate aminotransferase RL4338 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 116252443 Common - putative acylphosphatase RL2696 132 COG1254 AcyP, Acylphosphatases Energy production and conversion 116251607 Nonpathogen - hypothetical protein RL1841 7 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 116251052 Common - hypothetical protein RL1285 10 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 116252280 Common - hypothetical protein RL2534 164 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 116251688 Common - hypothetical protein RL1924 18 None None None 116250571 Common - hypothetical protein RL0800 20 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 116253166 Common dctA C4-dicarboxylate transporter DctA RL3424 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 116251963 Common - hypothetical protein RL2207 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 116253959 Common exoI putative beta-hexosaminidase RL4222 56 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 116250431 Common - hypothetical protein RL0659 35 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 116253677 Common - hypothetical protein RL3937 5 None None None 116252797 Common - hypothetical protein RL3053 6 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 116251236 Common - putative glycosyl transferase RL1470 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251280 Common - putative two-component response regulator transcriptional regulatory protein RL1514 23 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116253082 Common - hypothetical protein RL3341 12 None None None 116250294 Common - putative purine deaminase RL0523 209 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 116254183 Common - putative transmembrane component of ABC transporter RL4452 225 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116254084 Common - putative transmembrane CBS domain family protein RL4351 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 116250596 Common - putative oxidoreductase RL0824 185 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250796 Common coxX protoheme IX farnesyltransferase RL1023 189 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 116251942 Nonpathogen - hypothetical protein RL2185 5 None None None 116252019 Nonpathogen - putative transmembrane protein RL2263 1 None None None 116252686 Common - putative methyltransferase RL2939 92 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116254393 Nonpathogen - hypothetical protein RL4668 1 None None None 116250601 Common - hypothetical protein RL0829 8 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 116250363 Common - acetyl-CoA acetyltransferase RL0592 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 116250974 Nonpathogen - hypothetical protein RL1207 3 None None None 116252908 Common - putative adenylate/guanylate cyclase RL3166 91 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 116251751 Common - putative glycerol phosphatase RL1988 93 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 116253842 Common argF putative ornithine carbamoyltransferase RL4105 206 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 116250724 Common - hypothetical protein RL0950 59 COG1683 COG1683, Uncharacterized conserved protein Function unknown 116253880 Common - putative glutamine amidotransferase RL4143 115 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 116251181 Common - putative GFO/IDH/MocA family oxidoreductase RL1415 147 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116253096 Common - putative ATP-binding component of ABC transporter RL3355 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116249796 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL0030 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 116252858 Common - hypothetical protein RL3116 4 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 116249773 Common fxsA FxsA RL0007 29 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 116252267 Common - putative IAA acetyltransferase RL2521 69 COG0456 RimI, Acetyltransferases General function prediction only 116251016 Nonpathogen - hypothetical protein RL1249 1 None None None 116253253 Common - putative dehydrogenase/oxidoreductase RL3511 187 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116250133 Common hutU urocanate hydratase RL0364 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 116253780 Common - putative transmembrane protein RL4041 43 COG0730 COG0730, Predicted permeases General function prediction only 116252573 Common cobE putative cobalamin biosynthesis protein RL2826 9 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 116254448 Common rsmB putative ribosomal RNA small subunit methyltransferase B RL4724 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 116251699 Nonpathogen - hypothetical protein with pentapeptide motif RL1935 2 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 116251411 Common - hypothetical protein RL1645 3 None None None 116251719 Common - putative transmembrane GGDEF sensory box protein RL1955 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116250629 Common - hypothetical protein RL0856 168 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 116254092 Common - putative TRAP family C4-dicarboxylate transmembrane transporter RL4359 68 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 116250342 Common - hypothetical protein RL0571 44 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 116251425 Common - putative transmembrane component of ABC transporter RL1659 165 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116252010 Common ispDF bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein RL2254 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 116251535 Common rpsL 30S ribosomal protein S12 RL1769 238 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 116250752 Nonpathogen - hypothetical protein RL0978 2 COG0824 FcbC, Predicted thioesterase General function prediction only 116251115 Common cycG putative diheme cytochrome c RL1347 53 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 116251038 Common betB betaine aldehyde dehydrogenase RL1271 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116253666 Nonpathogen - hypothetical protein RL3926 4 None None None 116250308 Common fixN putative cytochrome cbb3 oxidase subunit RL0536 144 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 116251902 Nonpathogen - hypothetical protein RL2144 3 None None None 116251558 Common rpmD 50S ribosomal protein L30 RL1792 49 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 116252820 Common - hypothetical protein RL3076 41 COG1396 HipB, Predicted transcriptional regulators Transcription 116254218 Common - putative glycosyl hydrolase RL4489 180 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 116250654 Common - putative transmembrane quinol oxidase subunit RL0880 62 COG2259 COG2259, Predicted membrane protein Function unknown 116251651 Common pduW putative propionate kinase RL1886 162 COG0282 ackA, Acetate kinase Energy production and conversion 116253789 Common ggt putative gamma-glutamyltranspeptidase precursor RL4050 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 116250712 Common - hypothetical protein RL0938 23 None None None 116252667 Common - putative transmembrane component of ABC transporter RL2920 96 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116250788 Common - putative polysaccharide deacetylase protein RL1015 31 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116252126 Common - putative transmembrane component of ABC transporter RL2374 109 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 116250566 Common - putative glucose-1-phosphate thymidylyltransferase RL0795 230 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 116253925 Common - hypothetical protein RL4188 3 None None None 116250296 Common - putative MarR family transcriptional regulator RL0525 108 COG1846 MarR, Transcriptional regulators Transcription 116253863 Common soxB putative sarcosine oxidase beta subunit RL4126 94 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116250303 Common fixI putative nitrogen fixation cation ATP-ase protein RL0532 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116250012 Common - putative methyltransferase RL0244 46 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116251592 Common - putative transmembrane component of ABC transporter RL1826 166 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116252132 Common - putative GntR family transcriptional regulator RL2380 138 COG2186 FadR, Transcriptional regulators Transcription 116253317 Nonpathogen - hypothetical protein RL3574 2 COG3340 PepE, Peptidase E Amino acid transport and metabolism 116251143 Common mrpD putative monovalent cation/H+ antiporter subunit D RL1375 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 116253047 Common murC UDP-N-acetylmuramate--L-alanine ligase RL3306 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 116252066 Nonpathogen - hypothetical protein RL2313 4 None None None 116251376 Nonpathogen - hypothetical protein RL1610 3 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116253064 Common - putative transmembrane efflux protein RL3323 124 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116253730 Common - putative exported phosphatase RL3991 91 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 116250587 Common - putative O-acetyl transferase RL0815 205 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116253883 Common - putative MarR family transcriptional regulator RL4146 105 COG1846 MarR, Transcriptional regulators Transcription 116252834 Common - putative transmembrane protein RL3091 116 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 116251265 Common ropA putative outer membrane protein RL1499 13 None None None 116251892 Common - hypothetical protein RL2132 77 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 116254114 Common - putative cell surface protein RL4381 142 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 116253555 Common - putative ATP-binding component of ABC transporter RL3814 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116249907 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase RL0140 140 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 116251210 Common - putative glutathione S-transferase I RL1444 89 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251334 Common - putative transmembrane protein RL1568 101 COG0795 COG0795, Predicted permeases General function prediction only 116253950 Common - putative hydrolase family protein RL4213 149 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 116253566 Nonpathogen - putative transmembrane protein RL3825 1 None None None 116252462 Common - putative iron transport ATP-binding component of ABC transporter protein RL2715 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 116254373 Common - putative ATP-binding component of ABC transporter RL4648 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116254351 Common - putative glutathione S-transferase RL4625 69 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251314 Common radA DNA repair protein RadA RL1548 204 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 116253324 Common - hypothetical protein RL3581 41 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 116251686 Nonpathogen - hypothetical protein RL1922 10 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 116251710 Nonpathogen - hypothetical protein RL1946 1 None None None 116251031 Common - putative alcohol dehydrogenase RL1264 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253481 Common - putative transmembrane component of ABC transporter RL3740 164 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 116251466 Common nqo1 NADH dehydrogenase subunit A RL1700 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 116253122 Nonpathogen - hypothetical protein RL3380 1 None None None 116253420 Common - putative TetR family transcriptional regulator RL3679 62 COG1309 AcrR, Transcriptional regulator Transcription 116253755 Common - hypothetical protein RL4016 18 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 116253193 Common - putative short-chain dehydrogenase/reductase RL3451 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116254049 Common - putative transmembrane ribonuclease protein RL4314 79 COG1295 Rbn, Predicted membrane protein Function unknown 116249933 Common phoT putative permease component of phosphate uptake ABC transporter protein RL0166 88 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 116250287 Common - putative component of ABC transporter RL0516 163 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116252734 Common - hypothetical protein RL2989 64 None None None 116254238 Common - putative transmembrane efflux protein RL4509 53 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116251949 Common - putative transposase-related protein RL2192 35 None None None 116252814 Nonpathogen - putative transmembrane protein RL3070 1 None None None 116252994 Common - hypothetical protein RL3251 19 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 116250007 Common - putative perosamine synthetase RL0240 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 116251617 Nonpathogen - hypothetical protein RL1851 4 None None None 116253503 Common - hypothetical protein RL3762 60 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 116252205 Common - putative transmembrane transporter RL2454 142 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116252300 Nonpathogen - hypothetical protein RL2554 1 None None None 116253741 Common - putative oxidoreductase RL4002 37 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116250455 Common - hypothetical protein RL0683 11 COG1476 COG1476, Predicted transcriptional regulators Transcription 116253890 Common - putative transmembrane sensory box GGDEF domain protein RL4153 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116254429 Common leuD isopropylmalate isomerase small subunit RL4705 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 116250229 Common - putative adenylate cyclase RL0458 48 COG5616 COG5616, Predicted integral membrane protein Function unknown 116252112 Common - hypothetical protein RL2360 89 COG2378 COG2378, Predicted transcriptional regulator Transcription 116249887 Common rpsO 30S ribosomal protein S15 RL0121 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 116250339 Common - putative phage-related transcriptional regulator RL0568 21 COG2932 COG2932, Predicted transcriptional regulator Transcription 116253448 Common pydA dihydropyrimidine dehydrogenase RL3708 125 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 116250256 Common - putative transmembrane sensory box GGDEF/EAL domain signalling protein RL0485 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116254235 Common typA putative GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A) RL4506 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 116250964 Common - putative oxidoreductase/dehydrogenase RL1197 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252320 Common - putative glycosyl transferase RL2574 47 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 116253027 Common - putative aminopeptidase RL3284 229 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 116253435 Nonpathogen - hypothetical protein RL3695 7 None None None 116250922 Nonpathogen - putative transmembrane protein RL1152 3 None None None 116253618 Common - putative solute-binding component of ABC transporter RL3878 68 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116249963 Common - putative outer membrane basic protein RL0196 107 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 116252542 Common - putative transmembrane component of ABC transporter RL2795 153 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116251074 Common - putative glyoxylase RL1306 43 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 116250570 Common - putative hexapeptide repeat transferase RL0799 85 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116252102 Common - putative amidohydrolase/decarboxylase RL2350 38 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 116253681 Nonpathogen - hypothetical protein RL3941 2 None None None 116253541 Common - putative oxidoreductase RL3800 178 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 116251917 Nonpathogen - hypothetical protein RL2159 1 None None None 116252851 Common - putative transmembrane component of ABC transporter RL3110 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250173 Common mviN putative transmembrane mviN virulence factor homologue RL0404 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 116254207 Common hemL putative glutamate-1-semialdehyde 2,1-aminomutase RL4477 233 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 116250046 Common - putative oxidoreductase RL0278 156 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116253926 Common - putative LysR family transcriptional regulator RL4189 192 COG0583 LysR, Transcriptional regulator Transcription 116250927 Common - hypothetical protein RL1159 8 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 116251111 Common - putative short-chain dehydrogenase/reductase RL1343 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253519 Common - putative short-chain dehydrogenase/reductase RL3778 229 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116252829 Common ectC L-ectoine synthase RL3086 35 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 116254452 Common - hypothetical protein RL4728 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 116252246 Common iorB putative isoquinoline 1-oxidoreductase beta subunit RL2500 94 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 116251085 Common - putative transmembrane protein RL1317 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 116250649 Nonpathogen - hypothetical protein RL0875A 1 None None None 116251274 Common - putative transmembrane protein RL1508 20 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 116252180 Common - putative transmembrane protein RL2428 170 COG0344 COG0344, Predicted membrane protein Function unknown 116253174 Common - putative glycerol trinitrate reductase RL3432 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 116254007 Common - hypothetical protein RL4270 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 116252231 Common - putative transmembrane transport protein RL2485 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116251909 Nonpathogen - hypothetical protein RL2151 1 None None None 116254344 Common - hypothetical protein RL4618 63 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 116252970 Common - hypothetical protein RL3228 20 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116254420 Common - hypothetical protein RL4696 7 None None None 116250351 Common - putative Rrf2 transcriptional regulator RL0580 121 COG1959 COG1959, Predicted transcriptional regulator Transcription 116254066 Common ftsX putative cell division protein homolog RL4331 35 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 116252703 Common - putative glycosyl hydrolase RL2956 71 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 116254266 Common ccmC putative heme exporter protein c (cytochrome c-type biogenesis protein) RL4539 126 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 116249930 Common phnN putative ATP-binding phosphonate metabolism protein RL0163 98 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 116250777 Common - putative ATP-binding component of ABC transporter RL1004 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 116251561 Common adk putative adenylate kinase RL1795 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 161501792 Common carA carbamoyl phosphate synthase small subunit RL3411 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 116253144 Common rpoD RNA polymerase sigma factor RpoD RL3402 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 116254387 Common - hypothetical protein RL4662 11 None None None 116249954 Common - putative transmembrane component of ABC transporter RL0187 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 116252163 Common - putative transmembrane protein RL2411 4 None None None 116251883 Common - hypothetical protein RL2123 2 None None None 116252212 Common - putative kinase inhibitor RL2461 98 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 116252653 Common dhaK putative PTS-dependent dihydroxyacetone kinase,dihydroxyacetone binding subunit RL2906 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116249847 Common - putative polysaccharide degradation protein RL0081 20 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 116252397 Common - hypothetical protein RL2651 11 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 116253417 Common - putative transmembrane exo/endo phosphatase protein RL3676 7 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 116253149 Common recQ putative ATP-dependent DNA helicase RecQ RL3407 230 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 116251297 Common - hypothetical protein RL1531 108 COG2135 COG2135, Uncharacterized conserved protein Function unknown 116253443 Common - RNA polymerase sigma factor RL3703 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116253913 Common xylA xylose isomerase RL4176 69 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 116250076 Common - putative transcriptional regulator RL0308 56 COG3903 COG3903, Predicted ATPase General function prediction only 116251599 Nonpathogen - hypothetical protein RL1833 1 None None None 116251873 Nonpathogen - hypothetical protein RL2114 1 None None None 116250425 Common - hypothetical protein RL0653 7 None None None 116252435 Common nadE NAD synthetase RL2688 238 COG0171 NadE, NAD synthase Coenzyme metabolism 116253914 Common xylB putative xylulose kinase RL4177 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 116251576 Nonpathogen - hypothetical protein RL1810 1 None None None 116251368 Common cya putative transmembrane adenylate cyclase RL1602 56 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116252769 Common - putative polysaccharidase RL3024 26 None None None 116250066 Nonpathogen - putative transmembrane protein RL0298 5 None None None 116252512 Common - putative ArsR family transcriptional regulator RL2766 113 COG0640 ArsR, Predicted transcriptional regulators Transcription 116252403 Common - putative GGDEF/GAF domain sensory box protein RL2657 186 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 116252053 Nonpathogen - hypothetical protein RL2297 1 None None None 116252255 Common citA citrate synthase 2 RL2509 194 COG0372 GltA, Citrate synthase Energy production and conversion 116250957 Nonpathogen - hypothetical protein RL1189 5 None None None 116251240 Common - conserved hypothetical DGPF domain protein RL1474 44 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 116252035 Nonpathogen - hypothetical protein RL2279 1 None None None 116253280 Common - beta amino acid--pyruvate transaminase RL3538 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 116254282 Common - isopropylmalate isomerase large subunit RL4555 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 116252760 Common nhaP putative Na+/H+ antiporter protein RL3015 110 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 116254021 Common ask aspartate kinase RL4284 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 116253335 Nonpathogen - hypothetical protein RL3592 1 None None None 116251971 Common - conserved hypothetical HIT family protein RL2215 239 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 116251152 Common - putative AraC-like transcription regulator RL1384 122 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250866 Common - hypothetical protein RL1094 3 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 116251490 Common - hypothetical protein RL1724 28 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116251742 Common cysB cysteine synthase A RL1979 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 116252051 Common - putative short-chain dehydrogenase/reductase RL2295 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250162 Common - hypothetical protein RL0393 106 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 116252759 Common kup putative low affinity potassium transport system protein RL3014 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 116252942 Common ilvE branched-chain amino acid aminotransferase RL3200 208 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 116254390 Common - hypothetical protein RL4665 31 COG4889 COG4889, Predicted helicase General function prediction only 116251537 Common fus elongation factor G RL1771 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 116250979 Common - putative glutathione S-transferase RL1212 77 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116249986 Common tadC putative component of pilus protein RL0219 75 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 116250031 Common - putative transmembrane protein RL0263 24 COG1633 COG1633, Uncharacterized conserved protein Function unknown 116250933 Common - hypothetical protein RL1165 9 None None None 116253238 Common papS putative poly(A) polymerase RL3496 196 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 116253768 Common cheR putative chemotaxis protein methyltransferase RL4029 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 116250696 Common kup putative potassium uptake transport system protein RL0922 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 116250196 Common rbsK putative ribokinase RL0427 149 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116253986 Common - putative ATP-binding component of ABC transporter RL4249 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116253937 Nonpathogen - hypothetical protein RL4200 1 None None None 116253605 Common - putative mandelate racemase/muconate lactonising family protein RL3865 91 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116252175 Common - probable peptidase/protease RL2423 186 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 116253964 Common - short chain dehydrogenase RL4227 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253204 Nonpathogen - hypothetical protein RL3462 1 None None None 116250206 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase RL0437 142 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 116250852 Common - hypothetical protein RL1079 30 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 116253474 Common - hypothetical protein RL3733 30 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 116252695 Common - hypothetical protein RL2948 26 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 116252491 Common - putative aldehyde dehydrogenase RL2745 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116252382 Common alaS alanyl-tRNA synthetase RL2636 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116253218 Common clpS ATP-dependent Clp protease adaptor RL3476 110 COG2127 COG2127, Uncharacterized conserved protein Function unknown 116250633 Common - putative adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase) RL0860 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 116252732 Common - putative AsnC family transcriptional regulator RL2986 158 COG1522 Lrp, Transcriptional regulators Transcription 116250848 Common - putative modification methylase RL1075 143 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 116251492 Common - hypothetical protein RL1726 10 COG2388 COG2388, Predicted acetyltransferase General function prediction only 116250492 Common flaA2 putative flagellin A RL0720 75 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116254194 Common - putative solute-binding component of ABC transporter RL4463 181 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116251823 Nonpathogen - hypothetical protein RL2063 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 116250859 Common - hypothetical protein RL1087 6 None None None 116250887 Nonpathogen - hypothetical protein RL1115 1 None None None 116251151 Common - putative peptidoglycan binding transmembrane protein RL1383 12 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 116251499 Common - hypothetical protein RL1733 28 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 116252314 Common - putative transmembrane CrcB family homolog RL2568 122 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 116252144 Common glnA putative glutamine synthetase I RL2392 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 116252678 Common - putative methyl-accepting chemotaxis protein RL2931 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116250337 Common - hypothetical protein RL0566 15 None None None 116251065 Common - putative cold shock protein RL1298 175 COG1278 CspC, Cold shock proteins Transcription 116254029 Common - putative transmembrane protein RL4293 5 None None None 116252058 Common - putative 3-oxoacyl-[acyl-carrier-protein] reductase RL2302 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253897 Common - hypothetical protein RL4160 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116254154 Common - putative hydrolase RL4422 44 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 116251605 Nonpathogen - hypothetical protein RL1839 1 None None None 116252968 Common - hypothetical protein RL3226 80 COG2128 COG2128, Uncharacterized conserved protein Function unknown 116251577 Common dapA putative dihydrodipicolinate synthase RL1811 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116253453 Common - putative heme oxygenase RL3713 6 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 116252823 Nonpathogen - putative transmembrane protein RL3079 2 None None None 116249996 Common - putative LysR family transcriptional regulator RL0229 173 COG0583 LysR, Transcriptional regulator Transcription 116250952 Common - hypothetical protein RL1184 7 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 116250799 Common ctaE putative cytochrome c oxidase polypeptide III (cytochrome aa3 subunit 3) RL1026 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 116252861 Common - putative two-component system response regulator transcriptional regulatory protein RL3119 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116251051 Common gstB putative glutathione S-transferase RL1284 92 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116252592 Common aroE putative shikimate dehydrogenase RL2845 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 116251812 Common - putative peptidase RL2052 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 116254249 Common - hypothetical protein RL4522 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 116253825 Common - putative transmembrane protein RL4088 60 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 116250969 Common - putative LysR family transcriptional regulator RL1202 118 COG0583 LysR, Transcriptional regulator Transcription 116254189 Common - putative transmembrane component of ABC transporter RL4458 168 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116253338 Common - putative HTH-type transcriptional regulator RL3595 128 COG1609 PurR, Transcriptional regulators Transcription 116249968 Common punA purine nucleoside phosphorylase RL0201 157 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 116250984 Common - putative TetR family transcriptional regulator RL1217 62 COG1309 AcrR, Transcriptional regulator Transcription 116251825 Common - hypothetical protein RL2065 3 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 116252729 Common - putative aldo/keto reductase RL2983 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116254433 Common - putative transmembrane MFS family permease protein RL4709 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116251235 Common - putative transmembrane protein RL1469 14 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116253722 Common - hypothetical protein RL3983 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 116250675 Nonpathogen - hypothetical protein RL0901 1 None None None 116252332 Common - putative acetyltransferase RL2586 85 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116253509 Common purA adenylosuccinate synthetase RL3768 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 116254161 Common lpdA dihydrolipoamide dehydrogenase RL4429 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 116252976 Common - putative lipoprotein RL3234 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 116254004 Common acoD putative acetaldehyde dehydrogenase RL4267 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116253834 Common - putative transmembrane cation transporter protein RL4097 116 COG1285 SapB, Uncharacterized membrane protein Function unknown 116250822 Common - putative solute-binding component of ABC transporter RL1049 177 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 116253857 Common nodN putative nodulation protein N RL4120 66 COG2030 MaoC, Acyl dehydratase Lipid metabolism 116250481 Common fliE flagellar hook-basal body protein FliE RL0709 14 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 116250089 Common - hypothetical protein RL0321 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 116250093 Common - hypothetical protein RL0325 113 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116250464 Common cheY putative chemotaxis protein RL0692 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 116251666 Nonpathogen - hypothetical protein RL1901 1 None None None 116253306 Common - hypothetical protein RL3564 37 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 116251248 Common hisC histidinol-phosphate aminotransferase RL1482 217 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 116251107 Common - hypothetical protein RL1339 5 None None None 116252197 Common - putative transmembrane MFS family sugar transport protein RL2445 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250543 Common - putative nucleotidyltransferase RL0771 10 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 116250080 Common - hypothetical protein RL0312 25 COG1359 COG1359, Uncharacterized conserved protein Function unknown 116253369 Common - putative component of ABC transporter RL3626 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116254056 Common hbdA 3-hydroxybutyryl-CoA dehydrogenase RL4321 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 116251404 Common plsX fatty acid/phospholipid synthesis protein RL1638 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 116253820 Common - hypothetical protein RL4083 28 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 116250966 Nonpathogen - hypothetical protein RL1199 1 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116250942 Nonpathogen - hypothetical protein RL1174 1 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 116250531 Common - putative HTH transcription regulator protein RL0759 95 COG0583 LysR, Transcriptional regulator Transcription 116253109 Common - putative transmembrane component of ABC transporter RL3368 189 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116251716 Common - putative transmembrane protein RL1952 10 None None None 116252727 Common - putative methyltransferase RL2981 88 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 116250668 Common - putative patatin family protein RL0894 95 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 116254127 Common - putative LysR family transcriptional regulator RL4394 181 COG0583 LysR, Transcriptional regulator Transcription 116253136 Common - hypothetical protein RL3394 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 116250471 Common flhB flagellar biosynthesis protein FlhB RL0699 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 116251806 Common tatA twin argininte translocase protein A RL2046 31 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 116249928 Common - putative cell division DNA translocase protein RL0161 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 116254326 Common efp elongation factor P RL4600 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 116254454 Common prpE putative propionate--CoA ligase RL4730 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 116249790 Common folC putative FolC bifunctional protein [Includes: Folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (FPGS); Dihydrofolate synthase]. RL0024 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 116252449 Common - putative rhizobium adhering-like protein RL2702 7 None None None 116252675 Common - putative methyltransferase protein RL2928 90 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116253637 Common - hypothetical protein RL3897 13 None None None 116254012 Common - putative Acr/RND family efflux transmembrane transporter RL4275 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116250731 Common - hypothetical protein RL0957 12 None None None 116254184 Common - putative transmembrane component of ABC transporter RL4453 165 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116254072 Common tyrC cyclohexadienyl dehydrogenase RL4337 176 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 116251237 Common - putative transmembrane protein RL1471 9 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116253794 Common - putative LysR family transcriptional regulator RL4055 187 COG0583 LysR, Transcriptional regulator Transcription 116249908 Common cycM putative cytochrome c RL0141 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 116252182 Common - hypothetical protein RL2430 24 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 116252912 Common - conserved hypothetical hexapeptide repeat protein RL3170 207 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 116252946 Common - hypothetical protein RL3204 67 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 116252285 Common - hypothetical protein RL2539 16 COG3672 COG3672, Predicted periplasmic protein Function unknown 116250220 Common cspA putative cold shock protein RL0451 177 COG1278 CspC, Cold shock proteins Transcription 116254136 Common - putative transmembrane acyltransferase RL4403 13 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116251303 Common - putative transmembrane transporter protein RL1537 97 COG2962 RarD, Predicted permeases General function prediction only 116249862 Common - hypothetical protein RL0096 15 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 116253199 Common - hypothetical protein RL3457 14 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 116252484 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2738 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253357 Common - hypothetical protein RL3614 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 116253872 Common pntAB putative transmembrane NAD(P) transhydrogenase subunit alpha part 2 RL4135 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 116251680 Common - hypothetical protein RL1916 93 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 116253483 Common - hypothetical protein RL3742 64 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 116252217 Common - putative TerC family transmembrane efflux protein RL2470 90 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 116250900 Nonpathogen - hypothetical protein RL1128 1 None None None 116251251 Common - hypothetical protein RL1485 24 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 116252846 Common - putative hydrolase RL3105 71 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116251501 Common topA DNA topoisomerase I RL1735 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 116251276 Common sipS putative signal peptidase RL1510 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 116251475 Common nuoI NADH dehydrogenase subunit I RL1709 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 116249898 Common recR recombination protein RecR RL0131A 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 116250598 Common fcl putative GDP-L-fucose synthetase RL0826 222 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116252896 Common - hypothetical protein RL3154 17 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 116251709 Common - ribonucleotide-diphosphate reductase subunit alpha RL1945 190 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 116253859 Common soxG putative sarcosine oxidase gamma subunit RL4122 30 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 116254036 Common - hypothetical protein RL4300 18 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 116250242 Common - putative phospholipid N-methyltransferase RL0471 34 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 116250166 Common fur putative ferric uptake regulation protein RL0397 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 116250913 Common - putative adenylate cyclase RL1142 46 COG5616 COG5616, Predicted integral membrane protein Function unknown 116253565 Nonpathogen - putative transmembrane protein RL3824 9 None None None 116252310 Common - hypothetical protein RL2564 2 None None None 116250387 Common - putative arsenate reductase RL0615 69 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 116250741 Common - hypothetical protein RL0967 100 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 116251635 Common dksA putative DNAK suppressor protein RL1870 39 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 116254082 Common cobS putative aerobic cobaltochelatase RL4349 65 COG0714 COG0714, MoxR-like ATPases General function prediction only 116249952 Common - putative solute-binding component of ABC transporter RL0185 171 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 116253653 Nonpathogen - hypothetical protein RL3913 1 None None None 116252086 Common - hypothetical protein RL2333 41 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 116253102 Common - putative GntR family transcriptional regulator RL3361 132 COG2188 PhnF, Transcriptional regulators Transcription 116250394 Common - putative HlyD family secretion protein RL0622 133 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116251839 Common - hypothetical protein RL2079 17 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 116254098 Common eutB putative ethanolamine ammonia-lyase heavy chain RL4365 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 116251587 Common - putative CoA-transferase RL1821 91 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 116252441 Common gor glutathione reductase RL2694 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 116251856 Common - aminotransferase RL2096 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116251810 Common surE stationary phase survival protein SurE RL2050 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 116253876 Common - putative transmembrane sensory box GGDEF/EAL protein RL4139 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116250442 Common - hypothetical protein RL0670 30 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 116253956 Common - putative transcriptional regulator RL4219 64 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 116251324 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase NodG RL1558 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253808 Common - hypothetical protein RL4071 36 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 116251194 Common - putative TetR family transcriptional regulator RL1428 48 COG1309 AcrR, Transcriptional regulator Transcription 116254360 Common - putative solute-binding component of ABC transporter RL4634 187 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116253363 Common - hypothetical protein RL3620 16 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 116252113 Common nccN putative nickel-cobalt-cadmium resistance protein RL2361 28 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 116250285 Common cutC putative copper homeostasis protein RL0514 57 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 116250410 Common - putative solute-binding component of ABC transporter RL0638 195 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250310 Common - putative transmembrane protein RL0538 6 None None None 116253374 Common - putative glycosyltransferase RL3631 211 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116253397 Common - putative glycosyltransferase RL3655 16 COG5017 COG5017, Uncharacterized conserved protein Function unknown 116254261 Common - hypothetical protein RL4534 30 None None None 116250036 Common rplT 50S ribosomal protein L20 RL0268 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 116253159 Common - putative transmembrane protein RL3417 14 COG5395 COG5395, Predicted membrane protein Function unknown 116253128 Common - hypothetical protein RL3386 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 116249813 Common - putative transmembrane protein RL0047 2 None None None 116251079 Common - hypothetical protein RL1311 78 COG0433 COG0433, Predicted ATPase General function prediction only 116252785 Common - cytochrome c oxidase subunit iv. cytochrome c oxidase subunit iv RL3041 9 COG5605 COG5605, Predicted small integral membrane protein Function unknown 116254341 Common - putative CarD family transcriptional regulator RL4615 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 116251928 Nonpathogen - hypothetical protein RL2170 1 None None None 116253624 Common sitA putative substrate-binding Fur regulated salmonella iron ABC transporter RL3884 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 116251580 Common - putative short-chain dehydrogenase/reductase RL1814 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116253085 Common - putative dehydrogenase RL3344 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 116254033 Common - putative foldase/peptidyl-prolyl cis-trans isomerase RL4297 160 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 116254176 Common sdhA succinate dehydrogenase flavoprotein subunit RL4444 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 116250762 Common - putative GntR family transcriptional regulator RL0988 133 COG1802 GntR, Transcriptional regulators Transcription 116251307 Common - hypothetical protein RL1541 66 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116250419 Common - putative GFO/IDH/MocA family oxidoreductase RL0647 145 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116253249 Common - putative phosphoesterase RL3507 32 COG1409 Icc, Predicted phosphohydrolases General function prediction only 116251645 Common - putative CRP/FNR family transcriptional regulator RL1880 139 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116251283 Common - putative molybdenum cofactor sulfurase RL1517 53 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 116252271 Common - hypothetical protein RL2525 86 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 116253225 Common apt adenine phosphoribosyltransferase RL3483 194 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 116253094 Common - putative ATP-binding component of ABC transporter RL3353 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116251770 Common - hypothetical protein RL2007 91 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116254410 Common modB molybdate ABC transporter permease protein RL4686 180 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 116254142 Common atpH F0F1 ATP synthase subunit delta RL4410 176 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 116251083 Common zwf glucose-6-phosphate 1-dehydrogenase RL1315 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 116251357 Common - hypothetical protein RL1591 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 116250064 Common - putative LysR family transcriptional regulator RL0296 180 COG0583 LysR, Transcriptional regulator Transcription 116249793 Common - hypothetical protein RL0027 52 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 116252098 Common - putative solute-binding component of ABC transporter RL2345 24 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252693 Common - putative two component response regulator transcriptional regulatory protein RL2946 18 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116252794 Common - putative transmembrane ATP-binding cationic transporter RL3050 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 116252583 Common cobQ cobyric acid synthase RL2836 157 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 116250722 Common - hypothetical protein RL0948 3 None None None 116251448 Common - putative solute-binding component of ABC transporter RL1682 106 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 116251530 Common rplJ 50S ribosomal protein L10 RL1764 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 116251737 Common - putative transposase for insertion sequence element RL1973 107 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 116251779 Nonpathogen - hypothetical protein RL2016 2 None None None 116252622 Common - putative ion efflux protein RL2875 128 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116250211 Common ada putative ADA regulator (Methylated-DNA--protein-cysteine methyltransferase) RL0442 204 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 116254462 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA RL4738 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 116251768 Common - putative glutathione S-transferase RL2005 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251600 Nonpathogen - hypothetical protein RL1834 3 COG4278 COG4278, Uncharacterized conserved protein Function unknown 116250318 Common phoU putative phosphate transport system protein RL0546 201 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 116252730 Common - hypothetical protein RL2984 69 COG1846 MarR, Transcriptional regulators Transcription 116250704 Common rnhB ribonuclease HII RL0930 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 116250819 Nonpathogen - hypothetical protein RL1046 1 None None None 116251060 Common - hypothetical protein RL1293 85 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 116252588 Common - putative ATP-binding component of ABC transporter RL2841 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116250976 Common - putative LysR family transcriptional regulator RL1209 141 COG0583 LysR, Transcriptional regulator Transcription 116250580 Nonpathogen - putative transmembrane protein RL0809 1 None None None 116251160 Common - putative transmembrane protein RL1392 18 COG5402 COG5402, Uncharacterized conserved protein Function unknown 116253695 Nonpathogen - hypothetical protein RL3955 1 None None None 116253181 Nonpathogen lpcB putative CMP KDO transferase RL3439 2 None None None 116253433 Common - hypothetical protein RL3692 3 None None None 116252340 Common deaD putative cold-shock DeaD-box protein A (ATP-dependent RNA helicase) RL2594 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 116252537 Common - putative GFO/IDH/MocA family oxidoreductase RL2790 155 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250895 Nonpathogen - hypothetical protein RL1123 2 None None None 116252492 Common - putative fucose binding protein RL2746 31 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 116251515 Common dhaK putative PTS-dependent dihydroxyacetone kinase,dihydroxyacetone binding subunit RL1749 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116251021 Common - hypothetical protein RL1254 50 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 116252225 Common - putative outer membrane protein RL2478 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 116253592 Nonpathogen - hypothetical protein RL3851 2 None None None 116249989 Common - putative peptidase RL0222 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 116252578 Common cobW putative cobalamin biosynthesis protein RL2831 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 116252072 Common - hypothetical protein RL2319 125 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 116250714 Common mntH manganese transport protein MntH RL0940 102 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 116254300 Common - putative GntR family transcriptional regulator RL4574 110 COG2186 FadR, Transcriptional regulators Transcription 116250515 Common - putative folate-dependent dehydrogenase/hydrolase/synthetase protein RL0743 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 116253279 Common nolR putative nodulation protein RL3537 146 COG0640 ArsR, Predicted transcriptional regulators Transcription 116250052 Common - putative MarR family transcriptional regulator RL0284 114 COG1846 MarR, Transcriptional regulators Transcription 116254288 Common xthA putative exodeoxyribonuclease III RL4561 193 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 116253429 Common - putative TetR family transcriptional regulator RL3688 24 COG1309 AcrR, Transcriptional regulator Transcription 116251317 Common dnaC replicative DNA helicase RL1551 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 116252368 Common - hypothetical protein RL2622 130 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 116252424 Nonpathogen - hypothetical protein RL2677 1 None None None 116253646 Common - putative solute-binding component of ABC transporter RL3906 138 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 116251215 Common - hypothetical protein RL1449 5 None None None 116251109 Common - hypothetical protein RL1341 8 COG1409 Icc, Predicted phosphohydrolases General function prediction only 116254289 Common - hypothetical protein RL4562 37 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 116252029 Common apbE putative thiamine biosynthesis protein RL2273 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 116252933 Common - putative exo/endo phosphatase RL3191 8 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 116254041 Nonpathogen - hypothetical protein RL4305 2 None None None 116251133 Common - putative glyoxylase RL1365 40 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 116252873 Common - putative glycerophosphoryl diester phosphodiesterase RL3131 147 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 116251627 Common - putative AsnC family transcriptional regulator RL1862 139 COG1522 Lrp, Transcriptional regulators Transcription 116254310 Common fbpA putative iron(III)-binding periplasmic protein precursor RL4584 125 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 116253505 Common - putative transmembrane protein RL3764 7 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116254295 Common - hypothetical protein RL4569 101 COG2835 COG2835, Uncharacterized conserved protein Function unknown 116250356 Common - putative RibD family protein RL0585 69 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116253469 Common ureE putative urease accessory protein RL3728 58 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 116252565 Common fnrN putative FNR family transcriptional regulator RL2818 129 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116249803 Common pckA phosphoenolpyruvate carboxykinase RL0037 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 116251191 Common - putative glutathione S-transferase RL1425 115 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116253643 Nonpathogen - hypothetical protein RL3903 1 None None None 116250020 Common nodL putative nodulation protein RL0252 86 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116254103 Nonpathogen - hypothetical protein RL4370 2 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 116249980 Common cpaB putative pilus assembly protein RL0213 60 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 116253262 Common - hypothetical protein RL3520 3 None None None 116251041 Common - hypothetical protein RL1274 5 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 116252100 Common - putative transmembrane component of ABC transporter RL2347 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116251866 Common - hypothetical protein RL2105 8 None None None 116250505 Common flgD flagellar basal body rod modification protein RL0733 47 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 116252805 Nonpathogen - hypothetical protein RL3061 1 None None None 116253390 Common - putative galactosyl transferase RL3648 5 None None None 116253302 Common map methionine aminopeptidase RL3560 245 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 116252178 Common - putative transmembrane protein RL2426 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253514 Common - putative 2-hydroxy-3-oxopropionate reductase RL3773 187 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 116253906 Common - putative transmembrane DoxD family protein RL4169 37 COG2259 COG2259, Predicted membrane protein Function unknown 116253944 Common - putative endonuclease III RL4207 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 116251320 Common rpsR 30S ribosomal protein S18 RL1554 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 116253402 Common - hypothetical protein RL3661 2 None None None 116250523 Common edd phosphogluconate dehydratase RL0751 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 116254325 Common - putative lysyl-tRNA synthetase homolog RL4599 200 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 116250248 Common dadA putative D-amino acid dehydrogenase RL0477 131 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116252629 Nonpathogen - hypothetical protein RL2882 7 None None None 116254061 Common - putative transmembrane protein RL4326 28 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 116251870 Nonpathogen - hypothetical protein RL2109 1 None None None 116251700 Nonpathogen - hypothetical protein RL1936 1 None None None 116251048 Nonpathogen - putative transmembrane protein RL1281 1 None None None 116254070 Common - hypothetical protein RL4335 14 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 116252658 Common - putative hydrolase RL2911 36 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116252772 Common - putative transmembrane protein RL3027 29 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116252434 Common - putative TolB-like protein RL2687 129 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 116251696 Common - putative modification methylase RL1932 125 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 116253332 Common goxB putative glycine oxidase RL3589 53 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116253346 Common - putative transmembrane transporter RL3603 27 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 116253176 Common - hypothetical protein RL3434 49 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116254240 Common - putative transmembrane acyl-CoA dehydrogenase RL4513 128 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 116251407 Common - putative MerR family transcriptional regulator RL1641 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 116254381 Common - hypothetical protein RL4656 33 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 116251137 Common - putative pentapeptide repeat protein RL1369 88 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 116249973 Common - adenosine deaminase RL0206 108 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 116250555 Common idnK putative gluconokinase RL0783 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 116254279 Common rplS 50S ribosomal protein L19 RL4552 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 116250476 Common flgF flagellar basal body rod protein FlgF RL0704 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 116253708 Common - putative OmpA family peptidoglycan-associated lipoprotein precursor RL3968 134 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 116252604 Common - chromosome replication initiation inhibitor protein RL2857 97 COG0583 LysR, Transcriptional regulator Transcription 116251726 Nonpathogen - putative transmembrane protein RL1962 1 None None None 116252748 Common arcB putative ornithine cyclodeaminase RL3003 82 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 116251292 Common - hypothetical protein RL1526 7 None None None 116253319 Common - putative transmembrane protein RL3576 36 COG3748 COG3748, Predicted membrane protein Function unknown 116253035 Nonpathogen - hypothetical protein RL3294 2 None None None 116251379 Common - putative transmembrane protein RL1613A 19 COG2962 RarD, Predicted permeases General function prediction only 116251342 Common - putative ATP-binding component of ABC transporter RL1576 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116253012 Common - putative AcrB/AcrD/AcrF RND family transmembrane transporter RL3269 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116254415 Common - putative peptidase RL4691 111 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 116252296 Common - putative MerR family transcriptional regulator RL2550 52 COG0789 SoxR, Predicted transcriptional regulators Transcription 116251524 Common - putative dehydratase/oxidoreductase RL1758 216 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116252417 Common - putative oxidoreductase RL2670 38 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 116254257 Common - putative ATP-binding component of ABC transporter RL4530 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 116252989 Common dapA putative dihydrodipicolinate synthase RL3247 186 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116251299 Common psd phosphatidylserine decarboxylase RL1533 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 116251382 Common hemB delta-aminolevulinic acid dehydratase RL1616 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 116254272 Common dapF diaminopimelate epimerase RL4545 183 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 116250235 Common - hypothetical protein RL0464 3 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 116253164 Common greA transcription elongation factor GreA RL3422 203 COG0782 GreA, Transcription elongation factor Transcription 116251861 Common - putative glyoxalase RL2101 124 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116252356 Common - putative GntR family transcriptional regulator RL2610 151 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 116253772 Common mcpB putative methyl accepting chemotaxis protein RL4033 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116253583 Common - putative solute-binding component of ABC transporter RL3842 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116253312 Common xdhA putative xanthine dehydrogenase RL3570 122 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 116250884 Nonpathogen - putative transmembrane protein RL1112 1 COG3402 COG3402, Uncharacterized conserved protein Function unknown 116249850 Common - hypothetical protein RL0084 19 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 116254446 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase RL4722 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 116252243 Common - hypothetical protein RL2497 23 COG3897 COG3897, Predicted methyltransferase General function prediction only 116251433 Common - putative transmembrane protein RL1667 52 None None None 116252632 Common - putative acetyltransferase RL2885 10 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116253710 Common tolA putative TolA outer membrane protein RL3971 19 COG5373 COG5373, Predicted membrane protein Function unknown 116252349 Common - putative transmembrane protein RL2603 39 COG5473 COG5473, Predicted integral membrane protein Function unknown 116253283 Common ade putative adenine deaminase RL3541 75 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 116253816 Common kdsD putative arabinose 5-phosphate isomerase RL4079 164 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 116253990 Common - putative LacI family transcriptional regulator RL4253 126 COG1609 PurR, Transcriptional regulators Transcription 116251003 Common - putative arylsulfatase RL1236 87 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116249990 Common - putative MarR family transcriptional regulator RL0223 16 COG1846 MarR, Transcriptional regulators Transcription 116252173 Common - putative solute-binding component of ABC transporter RL2421 100 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253717 Nonpathogen - hypothetical protein RL3978 1 None None None 116252040 Common hfq RNA-binding protein Hfq RL2284 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 116252452 Common - putative GGDEF sensory box protein RL2705 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116252470 Common - short chain dehydrogenase RL2723 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250905 Common - putative HTH family transcriptional regulator RL1133 170 COG0640 ArsR, Predicted transcriptional regulators Transcription 116254256 Common - putative lipase/arylesterase RL4529 106 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116253701 Common serC phosphoserine aminotransferase RL3961 62 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 116249922 Common - hypothetical protein RL0155 14 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 116252107 Common - putative carboxymuconolactone decarboxylase RL2355 87 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 116254331 Common galM putative aldose 1-epimerase RL4605 95 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 116253293 Common - putative exported lipase/esterase RL3551 136 COG0657 Aes, Esterase/lipase Lipid metabolism 116253578 Nonpathogen - hypothetical protein RL3837 5 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 116253596 Common - putative cytochrome c protein RL3855 59 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 116253113 Common - putative GntR family transcriptional regulator RL3372 131 COG1802 GntR, Transcriptional regulators Transcription 116251397 Nonpathogen - hypothetical protein RL1631 2 None None None 116251783 Common - putative solute-binding component of cationic transporter RL2022 80 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 116251757 Common nasT putative two component assimilatory nitrate reductase regulator response regulatory protein RL1994 103 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 116253460 Common - putative ATP-binding component of ABC transporter RL3720 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 116249913 Common - putative acetyltransferase RL0146 9 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116252641 Common - putative transmembrane transporter RL2894 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253152 Common - putative GatB/Yqey family protein RL3410 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 116254158 Common xerC site-specific tyrosine recombinase XerC RL4426 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116252771 Common - putative transmembrane protein RL3026 65 COG2962 RarD, Predicted permeases General function prediction only 116252393 Common - hypothetical protein RL2647 6 None None None 116254128 Common - putative transcriptional regulator RL4395 161 COG0640 ArsR, Predicted transcriptional regulators Transcription 116254241 Common arsA putative arsenical translocating ATPase RL4514 95 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 116250924 Common - putative glycosyl transferase RL1155 8 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 116250929 Common - hypothetical protein RL1161 78 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 116254205 Common - putative TRAP family transporter component RL4474 107 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 116253957 Common exoD putative exopolysaccharide biosynthesis protein RL4220 46 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 116251232 Common glnA putative glutamine synthetase RL1466 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 116250827 Common - putative TetR family transcriptional regulator RL1054 36 COG1309 AcrR, Transcriptional regulator Transcription 116250850 Common - hypothetical protein RL1077 51 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116254422 Common - hypothetical protein RL4698 85 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 116250428 Common - putative mannosyltransferase/glycosyltransferase RL0656 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116250560 Common - putative ECF sigma factor RL0788 158 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116250289 Common - putative solute-binding component of ABC transporter RL0518 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253088 Common - putative transmembrane component of ABC transporter RL3347 114 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 116251188 Common - putative GntR family transcriptional regulator RL1422 143 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 116250576 Nonpathogen - putative transmembrane protein RL0805 3 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 116253112 Common - putative ATP-binding component of ABC transporter RL3371 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116253973 Common cyaB aputative adenylate/guanylate cyclase RL4236 73 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116252992 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase RL3249 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 116254144 Common priA primosome assembly protein PriA RL4412 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 116252736 Common - hypothetical protein RL2991 22 COG3698 COG3698, Predicted periplasmic protein Function unknown 116252284 Common pip putative proline iminopeptidase RL2538 108 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116252384 Common rbsK putative ribokinase RL2638 155 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116253379 Common - putative antibiotic resistance protein RL3636 25 COG3482 COG3482, Uncharacterized conserved protein Function unknown 116252064 Nonpathogen - hypothetical protein RL2308 5 None None None 116251212 Common pepN putative aminopeptidase N RL1446 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 116252302 Common - putative transmembrane protein RL2556 109 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 116252234 Common - hypothetical protein RL2488 73 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 116252165 Common - putative glycosidase RL2413 153 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 116251815 Common secD bifunctional preprotein translocase subunit SecD/SecF RL2055 212 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 116252427 Common - putative integrase/recombinase protein RL2680 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116250040 Common - putative aldo-keto reductase/oxidoreductase RL0272 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253753 Common - putative transmembrane transporter protein RL4014 68 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252339 Common - putative transmembrane peptidase family protein RL2593 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 116250585 Common - putative UDP-glucose epimerase RL0813 223 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116254284 Common dkgA putative 2,5-diketo-D-gluconic acid reductase A RL4557 185 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 116250413 Common - putative ROK family transcriptional regulator RL0641 161 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116250445 Common - putative two-component regulator sensory histidine kinase transcriptional regulatory protein RL0673 225 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 116252812 Common - putative two component sensor histidine kinase transcriptional regulatory protein RL3068 206 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116252837 Common - putative AsnC family transcriptional regulator RL3094 112 COG1522 Lrp, Transcriptional regulators Transcription 116251786 Common - putative transmembrane protein RL2025 14 None None None 116251076 Common - conserved ATP-binding component of ABC transporter RL1308 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 116251386 Common glyA serine hydroxymethyltransferase RL1620 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 116253277 Common - putative ATP-binding component of ABC transporter RL3535 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 116251455 Common clpX ATP-dependent protease ATP-binding subunit RL1689 220 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 116250177 Common - hypothetical protein RL0408 71 COG3176 COG3176, Putative hemolysin General function prediction only 116252042 Common mazG nucleoside triphosphate pyrophosphohydrolase RL2286 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 116253836 Nonpathogen - hypothetical protein RL4099 1 None None None 116252207 Common - putative dioxygenase RL2456 60 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116251552 Common rplE 50S ribosomal protein L5 RL1786 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 116250373 Common - putative transmembrane ionic channel RL0602 127 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116253544 Common - hypothetical protein RL3803 29 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 116250170 Common - putative universal stress protein RL0401 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116253441 Nonpathogen - putative transmembrane protein RL3701 2 COG4575 ElaB, Uncharacterized conserved protein Function unknown 116250259 Common - putative ROK family transcriptional regulator RL0488 84 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116253081 Common - hypothetical protein RL3340 43 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 116253941 Common - putative transcriptional regulator RL4204 63 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 116251869 Nonpathogen - putative transmembrane protein RL2108 1 None None None 116250175 Common mutS DNA mismatch repair protein RL0406 198 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 116251099 Common cyaA putative adenylate cyclase RL1331 81 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116249984 Common cpaF putative component of pilus RL0217 164 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 116252330 Common - hypothetical protein RL2584 87 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 116251888 Common - hypothetical protein RL2128 74 COG0433 COG0433, Predicted ATPase General function prediction only 116251785 Common katE putative catalase RL2024 124 COG0753 KatE, Catalase Inorganic ion transport and metabolism 116253553 Common - hypothetical protein RL3812 44 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 116250250 Common prdF putative proline racemase RL0479 48 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 116251986 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase RL2230 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 116252673 Common - putative adenylyl cylase RL2926 14 None None None 116254233 Common ppa inorganic pyrophosphatase RL4504 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 116249874 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase RL0108 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 116253497 Common - hypothetical protein RL3756 53 COG2388 COG2388, Predicted acetyltransferase General function prediction only 116250879 Common - putative transmembrane protein RL1107 17 COG4298 COG4298, Uncharacterized protein conserved in bacteria Function unknown 116251762 Common - putative transmembrane component of ABC transporter RL1999 121 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116253810 Common hss putative homospermidine synthase RL4073 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 116249821 Common - hypothetical protein RL0055 68 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116254006 Common - putative ThiJ/PfpI family protein RL4269 146 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 116254009 Common - putative cation/proton antiporter RL4272 57 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 116251272 Common relA putative stringent response protein RL1506 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 116251141 Common mrpB putative monovalent cation/H+ antiporter subunit B RL1373 90 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 116252020 Common - putative arylsulfatase RL2264 71 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116250787 Common pdxH pyridoxamine 5'-phosphate oxidase RL1014 133 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 116251258 Common iolB putative myoinositol catabolism protein RL1492 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 116251900 Common - hypothetical protein RL2141 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 116252437 Common - hypothetical protein RL2690 70 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116253315 Common - putative LysR family transcriptional regulator RL3573 173 COG0583 LysR, Transcriptional regulator Transcription 116250603 Nonpathogen - hypothetical protein RL0831 1 None None None 116250304 Common - hypothetical protein RL0533 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 116253613 Common rmeR putative TetR family transcriptional regulator RL3873 39 COG1309 AcrR, Transcriptional regulator Transcription 116253041 Common ftsQ putative cell division protein FtsQ RL3300 63 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 116252906 Common - hypothetical protein RL3164 90 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116250920 Common - hypothetical protein RL1150 3 None None None 116251424 Common - putative transmembrane component of ABC transporter RL1658 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116253130 Common - hypothetical protein RL3388 7 COG5664 COG5664, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 116251349 Common - putative transmembrane component of ABC transporter RL1583 101 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 116253005 Common mocA putative MocA family oxidoreductase RL3262 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116254099 Common eutC ethanolamine ammonia-lyase small subunit RL4366 52 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 116250405 Nonpathogen - hypothetical protein RL0633 1 None None None 116253427 Common - putative transporter component protein RL3686 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 116249935 Common phoD putative solute-binding component of phosphate uptake ABC transporter RL0168 80 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 116253543 Nonpathogen - putative transmembrane protein RL3802 1 None None None 116253865 Common cyaA putative transmembrane adenylate/guanylate cyclase RL4128 88 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 116250534 Common - putative HTH transcriptional regulator RL0762 45 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 116250972 Common - hypothetical protein RL1205 126 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116251924 Nonpathogen - hypothetical protein RL2166 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116253072 Common metF putative 5,10-methylenetetrahydrofolate reductase RL3331 140 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 116251967 Nonpathogen - hypothetical protein RL2211 15 COG5490 COG5490, Uncharacterized conserved protein Function unknown 116250344 Common dinF putative transmembrane DNA-damage inducible protein RL0573 97 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 116251335 Common - hypothetical protein RL1569 94 COG0795 COG0795, Predicted permeases General function prediction only 116253523 Common - 3-methyladenine DNA glycosylase RL3782 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 116252614 Common - hypothetical protein RL2867 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 116251217 Common - putative uracil-DNA glycosylase RL1451 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 116249949 Common glk glucokinase RL0182 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 116252856 Common - putative homologue of hemolysin protein RL3114 36 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116250349 Common - hypothetical protein RL0578 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 116253255 Common leuA 2-isopropylmalate synthase RL3513 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 116250014 Common ddhA putative glucose-1-phosphate cytidylyltransferase RL0246 145 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 116252124 Common - putative ATP-binding component of ABC transporter RL2372 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 116252157 Common - putative peptidyl-prolyl cis-trans isomerase B (cyclophilin-related protein) RL2405 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 116254319 Common - putative beta-mannosidase RL4593 38 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 116250736 Common - putative ring hydroxylating dioxygenase subunit RL0962 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 116250772 Common - putative two-component regulator sensor histidine kinase protein RL0999 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251556 Common rplR 50S ribosomal protein L18 RL1790 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 116251653 Nonpathogen - hypothetical protein RL1888 2 None None None 116252774 Common - putative ATP-binding component of ABC transporter RL3029 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116253269 Nonpathogen - hypothetical protein RL3527 8 COG3904 COG3904, Predicted periplasmic protein Function unknown 161501794 Common clpP ATP-dependent Clp protease proteolytic subunit RL1688 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116252265 Common - hypothetical protein RL2519 37 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 116253510 Common - putative transmembrane protein RL3769 169 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116253223 Common - putative MaoC family protein RL3481 60 COG2030 MaoC, Acyl dehydratase Lipid metabolism 116253729 Common ruvB Holliday junction DNA helicase B RL3990 227 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 116250810 Common - putative thioredoxin family protein RL1037 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116253886 Common - hypothetical protein RL4149 48 COG2319 COG2319, FOG: WD40 repeat General function prediction only 116250909 Common - hypothetical protein RL1137 74 COG3391 COG3391, Uncharacterized conserved protein Function unknown 116251263 Common - putative dehydrogenase/oxidoreductase RL1497 182 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250746 Common - putative methyl-accepting chemotaxis protein RL0972 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116250393 Common - putative insertion element related protein RL0621 51 None None None 116251018 Common degP putative serine protease RL1251 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116252551 Common - putative acetyltransferase RL2804 63 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116252370 Common rpsD 30S ribosomal protein S4 RL2624 221 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 116251647 Nonpathogen - hypothetical protein RL1882 1 None None None 116252668 Common - putative ATP-binding component of ABC transporter RL2921 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116253048 Common murG N-acetylglucosaminyl transferase RL3307 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 116253861 Common soxD putative sarcosine oxidase delta subunit RL4124 31 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 116250758 Common - putative ABC transporter component RL0984 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116250935 Common - putative TetR family transcriptional regulator RL1167 99 COG1309 AcrR, Transcriptional regulator Transcription 116254304 Common ggt putative gamma-glutamyltranspeptidase precursor RL4578 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 116251221 Common - putative aminoglycoside gentamicin resistance protein RL1455 4 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 116253942 Common - putative DNA repair methyltransferase RL4205 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 116254342 Common fdxA putative ferredoxin II (FdII) RL4616 155 COG1146 COG1146, Ferredoxin Energy production and conversion 116250719 Common aroA putative 3-phosphoshikimate 1-carboxyvinyltransferase RL0945 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 116252563 Common fabZ putative (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase RL2816 180 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 116250689 Common dgoA 2-dehydro-3-deoxy-6-phosphogalactonate aldolase RL0915 123 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 116250622 Common - putative transmembrane protein RL0849 16 COG5331 COG5331, Uncharacterized protein conserved in bacteria Function unknown 116251378 Common - putative SpoVT/AbrB family transcriptional regulatory protein RL1612 20 COG2336 MazE, Growth regulator Signal transduction mechanisms 116249916 Common - putative HTH-type transcriptional regulator RL0149 37 COG1396 HipB, Predicted transcriptional regulators Transcription 116254371 Nonpathogen - hypothetical protein RL4646 1 None None None 116251987 Common lpxA UDP-N-acetylglucosamine acyltransferase RL2231 160 COG1043 LpxA, Acyl- acyl carrier protein 116253472 Common ureC urease subunit alpha RL3731 100 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 116253066 Common - putative hydrolase RL3325 71 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 116252665 Common - hypothetical protein RL2918 144 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 116254323 Common - acyl carrier protein RL4597 7 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116253844 Common - putative two-component response regulator transcriptional regulatory protein RL4107 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116252033 Common - putative two-component response regulator transcriptional regulatory protein RL2277 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116250710 Common - conserved hypothetical TPR repeat protein RL0936 141 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 116250322 Common argF ornithine carbamoyltransferase RL0550 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 116252329 Common nifS putative cysteine desulfurase RL2583 233 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 116252750 Nonpathogen - hypothetical protein RL3005 1 None None None 116253562 Common - putative tyrosine-protein kinase involved in exopolysaccharide biosynthesis RL3821 65 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 116250541 Common - putative two-component regulator sensor histidine kinase protein RL0769 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251990 Common gltA type II citrate synthase RL2234 194 COG0372 GltA, Citrate synthase Energy production and conversion 116250915 Common - putative conjugated bile salt hydrolase RL1145 52 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 116253404 Nonpathogen pssO putative polysaccharide transport outer membrane protein RL3663 1 None None None 116251391 Common rfbB putative dTDP-glucose 4,6-dehydratase RL1625 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 116253451 Common - putative alcohol dehydrogenase RL3711 206 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116250032 Common - hypothetical protein RL0264 25 COG3672 COG3672, Predicted periplasmic protein Function unknown 116252720 Common - putative FMN reductase family protein RL2974 96 COG0431 COG0431, Predicted flavoprotein General function prediction only 116252312 Common - putative hydrolase protein RL2566 142 COG0546 Gph, Predicted phosphatases General function prediction only 116253380 Common - hypothetical protein RL3637 41 COG1944 COG1944, Uncharacterized conserved protein Function unknown 116251464 Common - hypothetical protein RL1698 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 116252146 Common - putative carbohydrate kinase protein RL2394 219 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 116252791 Common - putative transmembrane efflux protein RL3047 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116250078 Common - putative alcohol dehydrogenase RL0310 213 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 116252264 Common - putative quinone oxidoreductase RL2518 180 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116252451 Nonpathogen - putative transmembrane protein RL2704 1 None None None 116253962 Common - putative TetR family transcriptional regulator RL4225 50 COG1309 AcrR, Transcriptional regulator Transcription 116254163 Common - hypothetical protein RL4431 5 None None None 116251821 Common - hypothetical protein RL2061 16 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 116251497 Common rpmG 50S ribosomal protein L33 RL1731 114 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 116252316 Common - hypothetical protein RL2570 81 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 116250568 Common - putative transmembrane protein RL0797 12 COG2246 COG2246, Predicted membrane protein Function unknown 116251615 Common - hypothetical protein RL1849 17 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116252258 Common secG preprotein translocase subunit SecG RL2512 14 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 116251579 Common - putative 2-dehydropantoate 2-reductase RL1813 112 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 116253387 Common exoV putative succinoglycan biosynthesis protein RL3645 12 None None None 116253607 Nonpathogen - hypothetical protein RL3867 2 None None None 116252219 Common - putative DNAse RL2472 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 116252458 Common moaA molybdenum cofactor biosynthesis protein A RL2711 202 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 116251285 Common - putative GGDEF/EAL sensory box domain protein RL1519 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116253746 Common gap putative glyceraldehyde-3-phosphate dehydrogenase RL4007 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 116252535 Common - putative glycosyl hydrolase RL2788 40 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 116249871 Common - hypothetical protein RL0105 2 None None None 116251849 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit RL2089 189 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 116253668 Common - hypothetical protein RL3928 9 None None None 116250071 Common - putative aldo/keto reductase RL0303 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116251597 Common - putative oxidoreductase/dehydrogenase flavoprotein binding RL1831 125 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 116252711 Common cspA putative cold shock protein CspA RL2964 177 COG1278 CspC, Cold shock proteins Transcription 116252195 Common - putative LysR family transcriptional regulator RL2443 191 COG0583 LysR, Transcriptional regulator Transcription 116252825 Common - hypothetical protein RL3081 37 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116250494 Common - hypothetical protein RL0722 9 None None None 116254027 Common - hypothetical protein RL4291 74 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116249798 Common - putative phosphocarrier protein HPr RL0032 94 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 116253234 Common - putative transmembrane transporter RL3492 82 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 116250098 Common - hypothetical protein RL0330 46 COG5470 COG5470, Uncharacterized conserved protein Function unknown 116251402 Common - hypothetical protein RL1636 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 116253827 Common - putative lysophospholipase RL4090 73 COG2267 PldB, Lysophospholipase Lipid metabolism 116253490 Common - putative transmembrane component of ABC transporter RL3749 153 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 116250666 Common - putative ribosomal large subunit pseudouridine synthase B RL0892 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 116251049 Common - putative deoR family transcriptional regulator RL1282 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 116252868 Common - hypothetical protein RL3126 16 None None None 116251625 Common phhA phenylalanine 4-monooxygenase RL1860 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 116250631 Common - putative NUDIX family protein RL0858 28 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 116250790 Common - hypothetical protein RL1017 4 COG1694 MazG, Predicted pyrophosphatase General function prediction only 116253216 Common pth peptidyl-tRNA hydrolase RL3474 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 116249889 Common truB tRNA pseudouridine synthase B RL0123 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 116250824 Common - hypothetical protein RL1051 4 None None None 116253591 Common dgoD putative galactonate dehydratase RL3850 138 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116251842 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B RL2082 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 116250937 Common - conserved hypothethetical protein RL1169 10 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116252806 Common cya3 putative adenylate cyclase RL3062 42 COG5616 COG5616, Predicted integral membrane protein Function unknown 116253011 Common flaB putative flagellin protein RL3268 38 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116253090 Common - putative transcriptional regulator RL3349 88 COG1737 RpiR, Transcriptional regulators Transcription 116253260 Common - putative transmembrane cation efflux pump RL3518 199 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 116252540 Common - putative ATP-binding component of ABC transporter RL2793 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116249771 Common - DNA polymerase III subunit epsilon RL0005 192 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 116252575 Common - putative helix-turn-helix transcriptional regulatory protein RL2828 33 COG1396 HipB, Predicted transcriptional regulators Transcription 116251572 Common degQ putative protease DegQ precursor RL1806 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116252724 Common - putative transcriptional regulator RL2978 75 COG1733 COG1733, Predicted transcriptional regulators Transcription 116251907 Nonpathogen - hypothetical protein RL2149 1 None None None 116250775 Common bioY putative transmembrane biotin biosynthesis protein RL1002 98 COG1268 BioY, Uncharacterized conserved protein General function prediction only 116251663 Common - hypothetical protein RL1898 10 None None None 116250977 Common - hypothetical protein RL1210 24 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 116250148 Common - putative glyoxalase family protein RL0379 34 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116254464 Common rho transcription termination factor Rho RL4740 208 COG1158 Rho, Transcription termination factor Transcription 116251563 Common rpsK 30S ribosomal protein S11 RL1797 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 116251129 Common - hypothetical protein RL1361 10 None None None 116250151 Common - putative GrpE heat shock protein RL0382 220 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 116250673 Common - putative maturation protein RL0899 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 116252626 Common - putative AraC family transcriptional regulator RL2879 149 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 116250029 Common - putative transmembrane protein RL0261 58 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 116252972 Common rrf2 putative Rrf2 family transcriptional regulator protein RL3230 54 COG1959 COG1959, Predicted transcriptional regulator Transcription 116252151 Common ssb single-strand DNA-binding protein RL2399 208 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 116250106 Common - glutathione synthetase RL0338 137 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 116252940 Common - hypothetical protein RL3198 14 COG5634 COG5634, Uncharacterized conserved protein Function unknown 116253517 Common - putative lipase RL3776 84 COG0657 Aes, Esterase/lipase Lipid metabolism 116251881 Common - putative transmembrane protein RL2121 10 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 116252306 Common - hypothetical protein RL2560 90 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 116252782 Common - putative transmembrane permease protein RL3038 111 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 116252514 Common ssuC putative aliphatic sulfonates transport permease protein RL2768 199 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 116252789 Common ctaC putative cytochrome c oxidase subunit II RL3045 137 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 116251875 Common - hypothetical protein RL2116 66 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 116251517 Common - putative transcriptional regulator and PTS-dependent dihydroxyacetone kinase, fusion protein RL1751 94 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116252713 Common - putative heat-shock protease RL2966 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116249845 Common acsAB putative transmembrane cellulose synthase RL0079 70 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116250213 Common lldD putative lactate dehydrogenase RL0444 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 116252830 Common - putative LysR family transcriptional regulator RL3087 155 COG0583 LysR, Transcriptional regulator Transcription 116253025 Common - putative AzlC family transmembrane protein RL3282 103 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 116253462 Common - putative transmembrane component of ABC transporter RL3722 158 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 116250986 Common - putative transcriptional regulator RL1219 75 COG0640 ArsR, Predicted transcriptional regulators Transcription 116252056 Common - putative dehalogenase/hydrolase RL2300 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116253911 Common - putative ATP-binding component of ABC transporter RL4174 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116249831 Common - putative glycosyl transferase RL0065 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 116253322 Nonpathogen - putative phage-related protein RL3579 9 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 116253629 Common - putative transmembrane protein RL3889 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 116251187 Common - oxidoreductase RL1421 178 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253532 Common - putative short-chain dehydrogenase/reductase RL3791 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116250691 Common - putative nodulation protein, 3-oxoacyl-(Acyl carrier protein) reductase RL0917 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250488 Common fliP flagellar biosynthesis protein FliP RL0716 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 116251921 Nonpathogen - hypothetical protein RL2163 1 None None None 116253360 Common - putative solute-binding component of ABC transporter RL3617 90 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 116253988 Common - putative transmembrane component of ABC transporter RL4251 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116254064 Common - putative transmembrane protein RL4329 2 None None None 116251053 Nonpathogen - hypothetical protein RL1286 1 None None None 116253376 Common exoU putative UDP-hexose transferase RL3633 224 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116254075 Common gloB putative hydroxyacylglutathione hydrolase (glyoxalase ii) RL4340 165 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116252464 Common glpK putative glycerol kinase RL2717 177 COG0554 GlpK, Glycerol kinase Energy production and conversion 116251130 Common - hypothetical protein RL1362 23 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116251837 Common - putative acetyltransferase RL2077 27 COG0456 RimI, Acetyltransferases General function prediction only 116252420 Common - hypothetical protein RL2673 10 None None None 116250694 Common - putative ATP-binding mrp family protein RL0920 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 116251978 Common tsf elongation factor Ts RL2222 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 116249815 Common hslV ATP-dependent protease peptidase subunit RL0049 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 116251169 Nonpathogen - putative N-terminal transmembrane anchored protein RL1401 1 None None None 116251326 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II RL1560 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116252883 Common - putative transmembrane protein RL3142 21 None None None 116250111 Common - putative transmembrane protein RL0343 45 COG2962 RarD, Predicted permeases General function prediction only 116251192 Common - putative pyridoxine oxidase RL1426 47 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 116250190 Common - putative ABC transporter ATP-binding component RL0421 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 116251590 Common - putative solute-binding component of ABC transporter RL1824 65 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251817 Common - putative phytoene synthase RL2057 32 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 116251158 Nonpathogen - hypothetical protein RL1390 1 None None None 116251894 Nonpathogen - hypothetical protein RL2134 1 None None None 116250959 Common - putative transmembrane protein RL1191 4 COG3152 COG3152, Predicted membrane protein Function unknown 116251242 Common - conserved hypothetical DGPF protein RL1476 46 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 116252364 Common - hypothetical protein RL2618 18 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 116252705 Nonpathogen - hypothetical protein RL2958 1 None None None 116251808 Common tatC putative Sec-independent protein translocase protein RL2048 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 116251327 Common pabC putative aminodeoxychorismate lyase RL1561 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 116250312 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL0540 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 116252278 Common hisI phosphoribosyl-AMP cyclohydrolase RL2532 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 116253033 Common - putative acetyltransferase RL3292 63 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116253190 Common - putative MFS family transmembrane transporter RL3448 78 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116251309 Common cysS cysteinyl-tRNA synthetase RL1543 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116253651 Common rapB putative Rhizobium adhering protein RL3911 19 None None None 116252548 Common ddlA putative D-alanine--D-alanine ligase A RL2801 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 116249826 Common - ornithine cyclodeaminase RL0060 83 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 116252966 Common - putative DNA helicase RL3224 96 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 116250591 Common - putative imidazole glycerol phosphate synthase,subunit RL0819 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 116252919 Common znuC putative high-affinity zinc uptake system ATP-binding component of ABC transporter protein RL3177 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 116252938 Common - putative MarR family transcriptional regulator RL3196 109 COG1846 MarR, Transcriptional regulators Transcription 116252624 Common - putative transmembrane transporter RL2877 13 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 116251116 Common gstA putative glutathione-S-transferase protein RL1348 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116253365 Common - putative inositol 2-dehydrogenase RL3622 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250702 Common atpF F0F1 ATP synthase subunit B RL0928 25 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 116251355 Common - putative ropB outer membrane protein RL1589 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 116251570 Common - hypothetical protein RL1804 16 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 116254152 Common - putative inositol 2-dehydrogenase RL4420 140 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250038 Common pheT phenylalanyl-tRNA synthetase subunit beta RL0270 228 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 116252347 Common purB adenylosuccinate lyase RL2601 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 116252134 Common glmS D-fructose-6-phosphate amidotransferase RL2382 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 116253330 Common - putative polysaccharide deacetylase family protein RL3587 59 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 116250427 Common - hypothetical protein RL0655 16 None None None 116251943 Common - putative AAA family ATPase protein RL2186 59 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 116254031 Common - putative acetyltransferase RL4295 15 COG0456 RimI, Acetyltransferases General function prediction only 116252505 Common - putative glutathione S-transferase RL2759 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116253162 Common - putative helicase/glycosylase RL3420 158 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 116253971 Nonpathogen - putative transmembrane protein RL4234 2 COG2259 COG2259, Predicted membrane protein Function unknown 116253345 Common - putative efflux RND transporter protein RL3602 167 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116251951 Common - hypothetical protein RL2194 7 None None None 116250008 Common - onserved hypothetical protein RL0241 22 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 116252115 Common - hypothetical protein RL2363 61 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116253087 Common glnA putative glutamine synthetase RL3346 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 116251795 Common valS valyl-tRNA synthetase RL2035 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250063 Common - hypothetical protein RL0295 9 None None None 116251772 Common - hypothetical protein RL2009 129 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 116254247 Common - putative transmembrane component of ABC transporter RL4520 49 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 116251081 Common - hypothetical protein RL1313 11 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 116253786 Common - putative esterase/hydrolase RL4047 89 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116252001 Common - hypothetical protein RL2245 6 COG0456 RimI, Acetyltransferases General function prediction only 116254424 Common - hypothetical protein RL4700 50 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 116249951 Common mepA penicillin-insensitive murein endopeptidase RL0184 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 116253458 Common dht dihydropyrimidinase RL3718 207 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 116250844 Nonpathogen - hypothetical protein RL1071 1 None None None 116252027 Common - hypothetical protein RL2271 40 COG3439 COG3439, Uncharacterized conserved protein Function unknown 116250615 Common - putative guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase RL0842 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 116250001 Common exoZ exopolysaccharide production protein exoz RL0234 98 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116252885 Common - putative AraC family transcriptional regulatory protein RL3144 109 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250930 Common - putative response regulator RL1162 50 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116251418 Nonpathogen - hypothetical protein RL1652 1 None None None 116250760 Common - putative transmembrane component of ABC transporter RL0986 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116250954 Common - putative LysR family transcriptional regulator RL1186 162 COG0583 LysR, Transcriptional regulator Transcription 116253560 Nonpathogen - putative FNR/CRP family transcriptional regulator RL3819 8 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116253052 Common murF putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase RL3311 204 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 116251062 Common - putative peptidase RL1295 6 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 116253703 Common - putative transmembrane protein RL3963 3 None None None 116249915 Common recF recombination protein F RL0148 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 116251508 Common - putative N-acetylmuramoyl-L-alanine amidase RL1742 173 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 116251090 Nonpathogen - hypothetical protein RL1322 2 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116251735 Common - hypothetical protein RL1971 23 COG5470 COG5470, Uncharacterized conserved protein Function unknown 116250656 Common - hypothetical protein RL0882 3 None None None 116250270 Common - hypothetical protein RL0499 72 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116253104 Common - putative mannose-6-phosphate isomerase RL3363 49 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 116252006 Common flaR1 putative FlaR DNA topology modulation protein RL2250 42 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 116254014 Common - putative methyl-accepting chemotaxis protein RL4277 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116253171 Common - putative LysR family transcriptional regulator RL3429 190 COG0583 LysR, Transcriptional regulator Transcription 116252910 Common - putative nucleotidyltransferase RL3168 5 None None None 116250385 Common hisD histidinol dehydrogenase RL0613 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 116249925 Common - putative GGDEF/EAL domain transcriptional regulator RL0158 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116250072 Common - putative CoA reductase RL0304 155 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116252377 Common icd isocitrate dehydrogenase RL2631 62 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 116249891 Common infB translation initiation factor IF-2 RL0125 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 116249901 Common dnaX DNA polymerase III subunits gamma and tau RL0134 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 116253250 Common - hypothetical protein RL3508 10 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 116252924 Nonpathogen - hypothetical protein RL3182 9 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116250434 Common - putative lipase RL0662 31 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 116252168 Common - hypothetical protein RL2416 4 None None None 116250860 Nonpathogen - hypothetical protein RL1088 1 None None None 116250944 Common - hypothetical protein RL1176 73 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 116253635 Nonpathogen - putative transmembrane protein RL3895 2 None None None 116250368 Common - hypothetical protein RL0597 51 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116252953 Common - putative AraC family transcriptional regulator RL3211 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116253751 Common - putative fructose-bisphosphate aldolase RL4012 34 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 116252688 Common - putative short-chain dehydrogenase/oxidoreductase RL2941 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116251999 Common pdhC putative dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex RL2243 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 116251473 Common nqo3 NADH dehydrogenase subunit G RL1707 191 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 116252447 Common - hypothetical protein RL2700 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 116252681 Common - hypothetical protein RL2934 48 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 116252898 Common - putative MarR family transcriptional regulatory protein RL3156 26 COG1846 MarR, Transcriptional regulators Transcription 116249896 Common - putative transcriptional regulator/acetyltransferase RL0130 28 COG0456 RimI, Acetyltransferases General function prediction only 116253485 Common - putative LuxR family transcriptional regulator RL3744 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116252639 Common - hypothetical protein RL2892 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 116253792 Common - putative AraC family transcriptional regulator RL4053 114 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 116253358 Common - putative transmembrane component of ABC transporter RL3615 120 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 116249958 Common - nicotinate phosphoribosyltransferase RL0191 60 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 116251854 Common phaC putative poly(3-hydroxyalkanoate) polymerase (PHA synthase) RL2094 72 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 116254096 Common dacC putative penicillin-binding protein precursor RL4363 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116250168 Common - putative endopeptidase RL0399 198 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 116250868 Nonpathogen - hypothetical protein RL1096 1 None None None 116250503 Common flaF flagellar biosynthesis regulatory protein FlaF RL0731 12 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 116250671 Common - hypothetical protein RL0897 4 None None None 116253100 Common - putative solute-binding component of ABC transporter RL3359 77 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250882 Common - putative plasmid-stability like protein RL1110 50 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 116250990 Nonpathogen - hypothetical protein RL1223 2 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 116251603 Nonpathogen - putative transmembrane protein RL1837 1 None None None 116252487 Common - putative transmembrane thioredoxin/DipZ protein RL2741 107 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 116253874 Common - putative transmembrane protein RL4137 5 None None None 116251067 Common rpsU 30S ribosomal protein S21 RL1300 39 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 116250483 Common flgA flagellar basal body P-ring biosynthesis protein FlgA RL0711 40 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 116249860 Common - putative GFO/IDH/MocA family oxidoreductase RL0094 136 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250291 Common - putative aldo-keto reductase RL0520 163 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116251435 Common speB putative agmatinase RL1669 128 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 116254220 Common - hypothetical protein RL4491 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 116252070 Nonpathogen - hypothetical protein RL2317 3 None None None 116253310 Common glpK putative glycerol kinase RL3568 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 116251449 Common - putative transmembrane component of ABC transporter RL1683 228 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 116250223 Common rnpA ribonuclease P RL0454 61 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 116252013 Common glnG two component response regulator nitrogen regulation protein NR(I) RL2257 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116250022 Common lepA GTP-binding protein LepA RL0254 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 116254357 Common - putative transmembrane transporter RL4631 72 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 116250205 Common dapE succinyl-diaminopimelate desuccinylase RL0436 210 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 116251844 Common - putative acetyltransferase RL2084 55 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116252526 Common dgkA putative transmembrane diacylglycerol kinase RL2780 49 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 116251354 Common fabG short chain dehydrogenase RL1588 222 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251832 Common - putative transmembrane protein RL2072 3 None None None 116249943 Common phnH carbon-phosphorus lyase complex subunit RL0176 42 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 116253348 Common - putative transmembrane protein RL3605 9 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 116250261 Common - putative sugar permease component of ABC transporter RL0490 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116251453 Common - putative transmembrane GGDEF sensory box protein RL1687 168 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116251858 Nonpathogen - putative transmembrane protein RL2098 1 None None None 116253870 Common - hypothetical protein RL4133 11 None None None 116250733 Common - putative FAD binding oxidoreductase RL0959 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 116252354 Common purQ phosphoribosylformylglycinamidine synthase subunit I RL2608 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 116253039 Common ftsZ cell division protein FtsZ RL3298 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 116253611 Common - putative transmembrane transporter protein RL3871 105 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 116251179 Common groEL chaperonin GroEL RL1412 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 116252088 Common kdgD 5-dehydro-4-deoxyglucarate dehydratase RL2335 217 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116250831 Common argS putative arginyl-tRNA synthetase RL1058 239 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116252616 Nonpathogen - hypothetical protein RL2869 1 None None None 116249818 Common - hypothetical protein RL0052 6 None None None 116251337 Common pepA leucyl aminopeptidase RL1571 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 116252406 Common - putative ATP-binding component of ABC transporter RL2660 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 116253673 Nonpathogen - hypothetical protein RL3933 1 None None None 116253528 Common - putative transmembrane efflux transporter RL3787 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116250610 Nonpathogen - hypothetical protein RL0837 1 None None None 116250244 Nonpathogen - hypothetical protein RL0473 1 None None None 116254047 Common - putative endonuclease family protein RL4311 95 COG1403 McrA, Restriction endonuclease Defense mechanisms 116251380 Common - arginyl-tRNA-protein transferase RL1614 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 116252634 Common arsC2 putative arsenate reductase RL2887 113 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 116249852 Common - putative GFO/IDH/MocA family oxidoreductase RL0086 176 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250496 Common motC chemotaxis protein RL0724 11 None None None 116252415 Common - putative oxidoreductase RL2668 100 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 116253600 Common - putative transmembrane component of ABC transporter RL3860 197 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116250237 Nonpathogen - hypothetical protein RL0466 1 None None None 116250720 Common - putative transmembrane protein RL0946 13 COG4907 COG4907, Predicted membrane protein Function unknown 116250892 Common - hypothetical protein RL1120 2 None None None 116253521 Common - putative LysR family transcriptional regulator RL3780 174 COG0583 LysR, Transcriptional regulator Transcription 116254413 Common - hypothetical protein RL4689 197 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 116253124 Common - putative outer membrane protein related to bp26 antigen of Brucella RL3382 87 COG2968 COG2968, Uncharacterized conserved protein Function unknown 116254444 Common gdhB putative NAD-dependent glutamate dehydrogenase (NAD(+)-dependent glutamate dehydrogenase) RL4720 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 116250478 Common - putative flagella related protein RL0706 7 None None None 116251755 Common narK putative nitrate transport protein RL1992 106 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 116251748 Common phr putative deoxyribodipyrimidine photo-lyase RL1985 136 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 116251660 Nonpathogen - hypothetical protein RL1895 1 None None None 116249975 Common - putative transmembrane protein RL0208 14 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 116253633 Common dctB putative sensor histidine kinase transcriptional regulatory protein RL3893 196 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 116254200 Common - hypothetical protein RL4469 10 COG5589 COG5589, Uncharacterized conserved protein Function unknown 116252141 Common - hypothetical protein RL2389 175 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 116253110 Common - putative transmembrane component of ABC transporter RL3369 188 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116252241 Common moaC putative molybdenum cofactor biosynthesis protein RL2495 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 116253581 Common - putative substrate-binding protein component of ABC transporter RL3840 49 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250808 Common - hypothetical protein RL1035 128 COG1678 COG1678, Putative transcriptional regulator Transcription 116254156 Common - putative acetyltransferase RL4424 13 COG0456 RimI, Acetyltransferases General function prediction only 116253202 Common proC pyrroline-5-carboxylate reductase RL3460 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 116251919 Common - hypothetical protein RL2161 2 None None None 116253539 Common - putative ATP-binding component of ABC transporter RL3798 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 116254053 Common - putative transmembrane rhomboid family protein RL4318 65 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 116253285 Common - putative solute-binding component of ABC transporter RL3543 213 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 116251532 Common rpoB DNA-directed RNA polymerase subunit beta RL1766 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 116253999 Common - putative transmembrane cation transport ATPase RL4262 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116251913 Nonpathogen - putative transmembrane protein RL2155 1 None None None 116253559 Common - putative glycosyl transferase RL3818 117 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116252079 Common - putative transmembrane component of ABC transporter RL2326 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116252980 Common nhb2 putative low-molecular weight cobalt-containing nitrile hydratase subunit beta RL3238 18 None None None 116254250 Common - hypothetical protein RL4523 25 None None None 116251442 Common - putative transmembrane protein RL1676 55 None None None 116254015 Common - putative transmembrane peptidase family protein RL4278 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 116252655 Common - putative deacetylase RL2908 3 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 116252159 Common tgt queuine tRNA-ribosyltransferase RL2407 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 116252294 Common - putative transmembrane protein RL2548 24 COG3821 COG3821, Predicted membrane protein Function unknown 116252109 Common - hypothetical protein RL2357 12 COG4334 COG4334, Uncharacterized protein conserved in bacteria Function unknown 116253115 Common - hypothetical protein RL3374 4 None None None 116254302 Common - putative substrate-binding transmembrane transmembrane component of ABC transporter RL4576 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250605 Nonpathogen - putative transmembrane protein RL0833 1 None None None 116253272 Common - putative transmembrane protein RL3530 18 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 116254259 Common - putative transmembrane protein RL4532 139 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 116254337 Common - putative MarR family transcriptional regulator RL4611 16 COG1846 MarR, Transcriptional regulators Transcription 116252978 Common - putative transmembrane protein RL3236 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 116251741 Common sseA putative 3-mercaptopyruvate sulfurtransferase RL1977 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 116251637 Common - putative universal stress response protein RL1872 51 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116254135 Common - hypothetical protein RL4402 94 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 116250856 Common smc putative structural maintenance of chromosomes protein RL1084 175 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 116252399 Common - putative two-component regulator HPt domain protein RL2653 11 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 116253774 Common cheA putative two component sensor histidine kinase chemotaxis protein CheA RL4035 149 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 116250750 Common xseB exodeoxyribonuclease VII small subunit RL0976 126 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 116252171 Common - putative transmembrane component of ABC transporter RL2419 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116253291 Common glnII putative glutamine synthetase II RL3549 92 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 116252792 Common - hypothetical protein RL3048 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 116254338 Common - putative transmembrane MFS family transport RL4612 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116254186 Common speB putative agmatinase RL4455 159 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 116252905 Common - putative short-chain dehydrogenase/oxidoreductase RL3162 221 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116254367 Common - putative glyoxalase protein RL4642 27 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 116252366 Common - putative inositol-1-monophosphatase RL2620 182 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116253146 Common tdh L-threonine 3-dehydrogenase RL3404 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 116252184 Common - hypothetical protein RL2431 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 116254435 Common - putative ATP-binding component of ABC transporter RL4711 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116253928 Common - putative ATP-binding component of ABC transporter RL4191 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116253398 Common - putative lipase RL3656 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116249880 Common - putative transmembrane protein RL0114 132 COG2860 COG2860, Predicted membrane protein Function unknown 116252931 Common - putative phenazine biosynthesis protein RL3189 109 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 116254391 Common pinE putative DNA-invertase from lambdoid prophage E14 RL4666 132 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 116251541 Common rplD 50S ribosomal protein L4 RL1775 221 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 116251011 Nonpathogen - putative transmembrane protein RL1244 1 None None None 116252494 Common - putative transmembrane component of ABC transporter RL2748 159 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250101 Common pmtA putative phospholipid N-methyltransferase RL0333 40 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 116251170 Common - hypothetical protein RL1402 3 None None None 116252516 Common ssuA putative aliphatic sulfonate substrate binding component of ABC transporter RL2770 84 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 116253410 Common - hypothetical protein RL3669 5 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116253069 Common - putative glycosyl transferase RL3328 45 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 116253264 Common - putative cation transport protein RL3522 104 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 116250801 Common - putative transmembrane protein RL1028 26 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 116254456 Common leuS leucyl-tRNA synthetase RL4732 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116253693 Nonpathogen - hypothetical protein RL3953 1 None None None 116252553 Common - putative hydrolase RL2806 79 COG0388 COG0388, Predicted amidohydrolase General function prediction only 116250054 Common - putative aminopeptidase RL0286 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 116252871 Common - putative serine/threonine protein phosphatase RL3129 143 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 116250513 Common - putative WecB family glycosyltransferase RL0741 109 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 116252386 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2640 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253641 Common ackA acetate kinase RL3901 161 COG0282 ackA, Acetate kinase Energy production and conversion 116251340 Common - putative GFO/IDH/MocA family oxidoreductase RL1574 147 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116253644 Common pobR putative AraC family transcriptional regulator for P-hydroxybenzoate hydroxylase RL3904 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116249964 Common - putative ATP-binding component of ABC transporter RL0197 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 116251613 Common - putative transcriptional regulator with adenylate cyclase domain RL1847 107 COG3903 COG3903, Predicted ATPase General function prediction only 116251205 Common ccmH putative cytochrome c-type biogenesis protein RL1439 47 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 116254370 Nonpathogen - hypothetical protein RL4645 1 None None None 116254403 Common - putative acetyltransferase RL4679 75 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116250748 Common - hypothetical protein RL0974 145 COG1741 COG1741, Pirin-related protein General function prediction only 116251294 Common - hypothetical protein RL1528 15 COG5451 COG5451, Predicted secreted protein Function unknown 116252783 Common - putative AraC family transcriptional regulator RL3039 54 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116254211 Common - putative solute-binding component of ABC transporter RL4482 149 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116251694 Common - putative ATP-dependent hydrolase protein RL1930 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 116253060 Common - putative transglycosylase RL3319 149 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 116250838 Common - putative methyl-accepting chemotaxis protein RL1065 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116254101 Common - putative transmembrane protein RL4368 6 None None None 116254178 Common sdhC putative succinate dehydrogenase cytochrome b556 subunit RL4446 55 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 116250521 Common aglK putative alpha-glucoside transport ATP-binding protein RL0749 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116250086 Common - hypothetical protein RL0318 9 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 116253905 Common abg putative beta-glucosidase RL4168 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 116252646 Common - putative ATP-binding component of ABC transporter RL2899 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116251485 Common proS prolyl-tRNA synthetase RL1719 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116253392 Common - putative glycosyltransferase RL3650 81 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251938 Common - hypothetical protein RL2181 22 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 116253419 Nonpathogen - hypothetical protein RL3678 1 None None None 116253852 Common glgB glycogen branching enzyme RL4115 142 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 116251046 Common - putative transmembrane MFS efflux transporter RL1279 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252844 Common - hypothetical protein RL3103 41 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 116251405 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III RL1639 203 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 116251872 Nonpathogen - hypothetical protein RL2113 1 None None None 116251390 Common rfbD putative dTDP-4-dehydrorhamnose reductase RL1624 164 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 116250354 Common - hypothetical protein RL0583 56 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 116251422 Common - putative acetyltransferase RL1656 10 COG0456 RimI, Acetyltransferases General function prediction only 116254293 Common tesB putative acyl-CoA thioesterase RL4567 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 116250378 Common uvrD putative uvrD ATP-dependent helicase RL0607 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 116253512 Common - putative GGDEF/EAL sensory box protein RL3771 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116252648 Common - putative PTS-dependent dihydroxyacetone kinase,ADP-binding subunit RL2901 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116251023 Common - putative nitrogen metabolite repression regulator RL1256 20 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116251958 Common aapM General L-amino acid transport system permease protein RL2202 181 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116253431 Common - putative transmembrane protein RL3690 10 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 116251322 Common - putative aldo-keto reductase RL1556 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116251728 Common - putative transmembrane protein RL1964 63 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116254121 Common - putative transmembrane permease protein RL4388 80 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 116251305 Common pip putative proline iminopeptidase RL1539 103 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116249976 Common - putative transmembrane protein RL0209 14 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 116250238 Common - putative O-methyl transferase RL0467 7 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116251623 Common - putative protease RL1858 138 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 116252486 Common - putative epoxide hydrolase RL2740 58 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116253359 Common - putative ATP-binding component of ABC transporter protein RL3616 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116250450 Nonpathogen - putative two-component response regulator transcriptional regulatory protein RL0678 1 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 116254204 Nonpathogen - hypothetical protein RL4473 1 None None None 116253425 Common - putative transmembrane protein RL3684 11 None None None 116251582 Common - putative nucleoside 2-deoxyribosyltransferase RL1816 19 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 116251384 Common - putative MarR family transcriptional regulator RL1618 22 COG1846 MarR, Transcriptional regulators Transcription 116254466 Common hemE uroporphyrinogen decarboxylase RL4742 175 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 116251474 Common nuoH NADH dehydrogenase subunit H RL1708 185 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 116252506 Common - putative ArsR family transcriptional regulator RL2760 52 COG0640 ArsR, Predicted transcriptional regulators Transcription 116254030 Common - putative NTP pyrophosphohydrolase RL4294 135 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116251929 Common - putative peptidase RL2172 24 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 116253062 Common - putative dnaJ-like chaperone RL3321 71 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 116252949 Nonpathogen - hypothetical protein RL3207 3 None None None 116251013 Common - hypothetical protein RL1246 8 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 116250537 Common - probable putrescine transport system permease protein RL0765 215 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116250658 Common groS putative 10 kda chaperonin (protein cpn10) RL0884 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 116253051 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase RL3310 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 116253350 Common - putative transmembrane protein RL3607 85 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116251526 Common nusG transcription antitermination protein NusG RL1760 215 COG0250 NusG, Transcription antiterminator Transcription 116251959 Common aapQ General L-amino acid transport system permease RL2203 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116253275 Common - putative solute-binding component of ABC transporter RL3533 62 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 116250876 Common - putative ketoreductase RL1104 95 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252362 Common - putative transmembrane efflux protein RL2616 223 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253301 Common - putative PadR family transcriptional regulator RL3559 78 COG1695 COG1695, Predicted transcriptional regulators Transcription 116252414 Common - putative TetR family transcriptional regulator RL2667A 19 COG1309 AcrR, Transcriptional regulator Transcription 116254124 Common fdsA putative NAD-dependent formate dehydrogenase alpha subunit RL4391 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 116253030 Common cheW putative chemotaxis protein RL3289 139 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 116253430 Common - putative globin family protein RL3689 67 COG2346 COG2346, Truncated hemoglobins General function prediction only 116253265 Common - hypothetical protein RL3523 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 116253342 Common - putative two-component response regulator transcriptional regulatory protein RL3599 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116254148 Common - putative transmembrane component of ABC transporter RL4416 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116252918 Common znuB putative high-affinity zinc uptake system membrane protein RL3176 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 116250123 Common - putative GntR family transcriptional regulator RL0354 140 COG2186 FadR, Transcriptional regulators Transcription 116253692 Nonpathogen - hypothetical protein RL3952 1 None None None 116250352 Common - putative transmembrane protein RL0581 53 COG1284 COG1284, Uncharacterized conserved protein Function unknown 116250084 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase RL0316 29 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 116254106 Common - putative ATP-binding component of ABC transporter RL4373 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116253764 Common suhB putative inositol-1-monophosphatase RL4025 213 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116252781 Nonpathogen - hypothetical protein RL3037 1 None None None 116254438 Nonpathogen - hypothetical protein RL4714 1 None None None 116252345 Nonpathogen - hypothetical protein RL2599 3 COG5497 COG5497, Predicted secreted protein Function unknown 116251685 Common - hypothetical protein RL1921 17 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 116254407 Common proA gamma-glutamyl phosphate reductase RL4683 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 116250057 Common - hypothetical protein RL0289 121 COG2606 EbsC, Uncharacterized conserved protein Function unknown 116251339 Nonpathogen - hypothetical protein RL1573 1 None None None 116253572 Common - putative O-acetyl transferase RL3831 32 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116253777 Common - hypothetical protein RL4038 107 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116252960 Common - putative TetR family transcriptional regulator RL3218 99 COG1309 AcrR, Transcriptional regulator Transcription 116252222 Common holB DNA polymerase III subunit delta' RL2475 228 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 116252746 Nonpathogen - putative transmembrane protein RL3001 1 None None None 116253037 Common comL putative competence lipoprotein ComL protein RL3296 129 COG4105 ComL, DNA uptake lipoprotein General function prediction only 116253638 Common - putative phosphotransferase protein RL3898 75 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116254329 Common - putative aminotransferase RL4603 234 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 116250209 Common - hypothetical protein RL0440 45 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116252788 Common ctaD putative cytochrome c oxidase subunit I RL3044 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 116252251 Common deaD putative cold-shock DEAD-box protein A (ATP-dependent RNA helicase DEAD) RL2505 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 116253645 Common pobA 4-hydroxybenzoate 3-monooxygenase RL3905 47 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 116252840 Nonpathogen - hypothetical protein RL3099 1 None None None 116253093 Common - putative transmembrane component of ABC transporter RL3352 191 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116249841 Common - putative GerE family transcriptional regulator RL0075 150 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116253713 Common - putative thioesterase family protein RL3974 126 COG0824 FcbC, Predicted thioesterase General function prediction only 116254253 Common phhB pterin-4-alpha-carbinolamine dehydratase RL4526 109 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 116253394 Common - putative glycosyl transferase RL3652 102 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116254046 Common - putative transmembrane protein RL4310 26 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 116252597 Common - hypothetical protein RL2850 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 116251952 Common - hypothetical protein RL2195 4 None None None 116250579 Common - hypothetical protein RL0808 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116252083 Nonpathogen - putative insertion sequence related protein RL2330 1 None None None 116253187 Common - putative transmembrane sortase-like protein RL3445 19 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 116253289 Common - putative ATP-binding component of ABC transporter protein RL3547 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116249854 Common - hypothetical protein RL0088 21 None None None 116250146 Common hemN coproporphyrinogen III oxidase RL0377 217 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 116254057 Common tlpA putative thiol:disulfide interchange protein RL4322 139 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 116251393 Common - hypothetical protein RL1627 10 None None None 116252282 Common - hypothetical protein RL2536 18 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 116249769 Common aroE shikimate 5-dehydrogenase RL0003 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 116250646 Common - putative haloacid dehydrogenase hydrolase RL0873 24 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 116251006 Nonpathogen - hypothetical protein RL1239 1 None None None 116251362 Common purM phosphoribosylaminoimidazole synthetase RL1596 230 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 116254273 Common - hypothetical protein RL4546 2 None None None 116250608 Common - putative Insertion sequence ATP-binding protein RL0836 54 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 116252390 Common - hypothetical protein RL2644 56 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 116250231 Nonpathogen - hypothetical protein RL0460 2 None None None 116252060 Common - hypothetical protein RL2304 23 COG5467 COG5467, Uncharacterized conserved protein Function unknown 116253167 Common dctB putative C4-dicarboxylate transport two-component sensor histidine kinase transcriptional regulatory protein RL3425 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 116250346 Common - putative transmembrane protein RL0575 14 None None None 116253997 Common nrdI ribonucleotide reductase stimulatory protein RL4260 36 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 116251122 Common gcd putative quinoprotein glucose dehydrogenase RL1354 61 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 116252288 Common - hypothetical protein RL2542 4 None None None 116252742 Common - putative phosphoglycerate mutase RL2997 138 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116252327 Nonpathogen - hypothetical protein RL2581 1 None None None 116253118 Common - hypothetical protein RL3376 5 None None None 116250805 Common rnhA ribonuclease H RL1032 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 116252074 Common - putative transmembrane protein RL2321 17 None None None 116254320 Common - hypothetical protein RL4594 7 None None None 116251441 Common - enoyl-CoA hydratase RL1675 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 116252636 Common - putative transmembrane transport protein RL2889 39 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253631 Common - hypothetical protein RL3891 64 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 116252062 Nonpathogen - hypothetical protein RL2306 1 None None None 116250468 Common - putative GerE/LuxR family transcriptional regulator RL0696 77 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116251705 Nonpathogen - hypothetical protein RL1941 1 None None None 116250321 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein RL0549 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 116251346 Common ndk nucleoside diphosphate kinase RL1580 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 116251746 Common - hypothetical protein RL1983 62 COG3496 COG3496, Uncharacterized conserved protein Function unknown 116254213 Common dapA putative dihydrodipicolinate synthase RL4484 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116250834 Common - putative peptidase RL1061 179 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 116254050 Common - short chain dehydrogenase RL4315 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116254336 Common - putative thiamine pyrophosphokinase RL4610 18 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 116252959 Common - putative MarR family transcriptional regulator RL3217 51 COG1846 MarR, Transcriptional regulators Transcription 116254187 Common - putative solute-binding component of ABC transporter RL4456 90 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116253331 Common - hypothetical protein RL3588 27 None None None 116254312 Common - putative oxidoreductase RL4586 133 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116253586 Common - putative transmembrane permease component of ABC transporter RL3845 166 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116254443 Common pdxK pyridoxamine kinase RL4719 97 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 116252369 Common glsA glutaminase RL2623 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 116252751 Common rhbB putative L-2,4-diaminobutyrate decarboxylase RL3006 91 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 116250592 Common hisH imidazole glycerol phosphate synthase subunit HisH RL0820 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 116254016 Common clpB putative chaperone ClpB (heat-shock protein) RL4279 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 116254377 Common - putative dipeptidase RL4652 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 116251944 Nonpathogen - hypothetical protein RL2187 1 None None None 116252104 Common - hypothetical protein RL2352 13 None None None 116253812 Common - putative 5'-nucleotidase RL4075 143 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 116251401 Common - putative outer membrane protein RL1635 30 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 116251589 Common - putative aldehyde dehydrogenase RL1823 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116251420 Common - hypothetical protein RL1654 14 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 116253364 Common - putative transmembrane protein RL3621 9 None None None 116250612 Nonpathogen - hypothetical protein RL0839 1 None None None 116251655 Nonpathogen - putative transmembrane protein RL1890 8 None None None 116250482 Common flgG flagellar basal body rod protein FlgG RL0710 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 116250854 Common - putative plasmid stabilisation-like protein RL1082 9 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 116254402 Common - putative acetyltransferase protein RL4678 99 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116252407 Common - putative transmembrane component of ABC transporter RL2661 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 116254191 Common - putative LysR family transcriptional regulator RL4460 155 COG0583 LysR, Transcriptional regulator Transcription 116250732 Common - hypothetical protein RL0958 20 None None None 116250883 Nonpathogen - hypothetical protein RL1111 3 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 116251639 Nonpathogen - hypothetical protein RL1874 1 None None None 116250981 Common - putative HTH family transcriptional regulator RL1214 102 COG0640 ArsR, Predicted transcriptional regulators Transcription 116251347 Common - hypothetical protein RL1581 4 None None None 116253527 Common - putative HlyD family secretion efflux protein RL3786 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116251043 Common - putative quinone oxidoreductase RL1276 201 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116253200 Common - putative beta-lactamase family protein RL3458 216 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116253621 Common - putative ATP-binding component of ABC transporter RL3881 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116254252 Common - hypothetical protein RL4525 37 COG3339 COG3339, Uncharacterized conserved protein Function unknown 116252777 Common - putative RNA binding protein RL3032 29 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116253817 Common - hypothetical protein RL4080 20 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 116250642 Common - putative exported ErfK/YbiS/YhnG protein RL0869 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116250266 Common - putative glyoxalase RL0495 23 None None None 116251966 Common - hypothetical protein RL2210 18 None None None 116252950 Common - hypothetical protein RL3208 7 None None None 116254180 Common - putative ribonuclease-L-PSP family protein RL4448 70 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116252121 Common - putative NADPH:ferredoxin reductase RL2369 105 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 116251300 Common - putative ATP-binding component of ABC transporter RL1534 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 116251608 Nonpathogen - hypothetical protein RL1842 3 None None None 116251257 Nonpathogen - hypothetical protein RL1491 2 None None None 116253809 Common - hypothetical protein RL4072 14 COG4994 COG4994, Uncharacterized protein conserved in bacteria Function unknown 116252798 Common - hypothetical protein RL3054 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 116251438 Common rpsI 30S ribosomal protein S9 RL1672 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 116254093 Common - putative C4-dicarboxylate transmembrane transporter protein RL4360 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 116253083 Common - putative ErfK/YbiS/YhnG family protein RL3342 90 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116252290 Common sdaA putative L-serine dehydratase RL2544 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 116253209 Common - hypothetical protein RL3467 12 None None None 116253802 Common - hypothetical protein RL4063 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 116250945 Common - putative transmembrane protein RL1177 81 COG1238 COG1238, Predicted membrane protein Function unknown 116252808 Common - putative aldo-keto reductase RL3064 194 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253530 Common - hypothetical protein RL3789 36 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 116249894 Common - hypothetical protein RL0128 161 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 116251469 Common nqo4 NADH dehydrogenase subunit D RL1703 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 116253075 Common rna putative ribonuclease I RL3334 34 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 116251058 Common - putative glycerophosphoryl diester phosphodiesterase RL1291 71 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 116253879 Common - putative solute-binding component of transporter RL4142 85 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 116250504 Common flbT flagellar biosynthesis repressor FlbT RL0732 21 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 116254085 Common aroB 3-dehydroquinate synthase RL4352 210 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 116252982 Common - putative transmembrane protein RL3240 82 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116253257 Common clpP ATP-dependent Clp protease proteolytic subunit RL3515 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116251960 Common aapJ General L-amino acid substrate binding protein RL2204 118 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116253904 Common - putative transmembrane sensory box GGDEF/EAL family protein RL4167 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116250108 Common cysK putative cysteine synthase RL0340 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 116253247 Common - hypothetical protein RL3505 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116250447 Common - putative two component sensor histidine kinase transcriptional regulatory protein RL0675 220 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 116254151 Common - putative GntR family transcriptional regulator RL4419 95 COG1802 GntR, Transcriptional regulators Transcription 116250295 Common - putative transmembrane component of ABC transporter RL0524 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 116250550 Common dppA putative dipeptide binding component of ABC transporter RL0778 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116251288 Common - putative transmembrane transporter RL1522 202 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116250376 Common - putative GGDEF sensory box family protein RL0605 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116251415 Common - hypothetical protein RL1649 5 COG5373 COG5373, Predicted membrane protein Function unknown 116252249 Common - putative short-chain dehydrogenase/oxidoreductase RL2503 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116250840 Nonpathogen - hypothetical protein RL1067 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 116251421 Common - putative ROK family transcriptional regulator RL1655 156 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116252036 Common - putative aldo-keto oxidoreductase RL2280 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116251788 Common - putative transmembrane protein RL2027 10 None None None 116252726 Common - putative TetR family transcriptional regulator RL2980 33 COG1309 AcrR, Transcriptional regulator Transcription 116251896 Common - putative transposase-related protein RL2136 53 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 116250382 Common - hypothetical protein RL0610A 3 None None None 116250034 Common infC translation initiation factor IF-3 RL0266 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 116249839 Common - hypothetical protein RL0073 6 None None None 116250473 Common fliN putative flagellar motor switch protein RL0701 121 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 116252870 Common - putative transmembrane protein RL3128 6 None None None 116252685 Common - putative transmembrane transporter RL2938 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253155 Common norM putative multidrug resistance protein NorM (Na(+)/drug antiporter) (multidrug-efflux transporter) RL3413 182 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 116251338 Common - DNA polymerase III subunit chi RL1572 51 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 116253471 Common - hypothetical protein RL3730 19 None None None 116252927 Common chrB putative chromate resistance protein RL3185 30 COG4275 COG4275, Uncharacterized conserved protein Function unknown 116252472 Common ribA putative riboflavin biosynthesis protein RL2726 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 116254170 Common sucC succinyl-CoA synthetase subunit beta RL4438 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 116252886 Common - putative dehydrogenases RL3145 8 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 116253520 Common - short chain dehydrogenase RL3779 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253744 Common - hypothetical protein RL4005 10 None None None 116252670 Common - putative AraC/XylS family transcriptional regulator RL2923 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 116251199 Common feuP putative two-component response regulator transcriptional regulatory protein RL1433 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116250880 Common - acylglycerophosphoethanolamine acyltransferase RL1108 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116254411 Common - putative ATP-binding component of ABC transporter RL4687 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 116250917 Nonpathogen - hypothetical protein RL1147 2 None None None 116251174 Common - putative transglutaminase family protein RL1406 82 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 116251202 Common cycH putative cytochrome c-type biogenesis protein RL1436 49 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 116249965 Common - putative transmembrane permease component of ABC transporter RL0198 106 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 116254221 Common - YciI-like protein RL4492 28 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 116251353 Common uvrC excinuclease ABC subunit C RL1587 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 116253132 Common fnrL putative transcriptional activator protein RL3390 60 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116253140 Nonpathogen - hypothetical protein RL3398 1 None None None 116251531 Common rplL 50S ribosomal protein L7/L12 RL1765 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 116250125 Common - hypothetical protein RL0356 71 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 116250562 Common - putative rhizobiocin RL0790 110 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 116250050 Common xseA exodeoxyribonuclease VII large subunit RL0282 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 116251118 Common - hypothetical protein RL1350 56 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 116251774 Common - putative component of ABC transporter RL2011 221 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116251773 Common - putative component of ABC transporter RL2010 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116251544 Common rpsS 30S ribosomal protein S19 RL1778 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 116254179 Nonpathogen - hypothetical protein RL4447 1 None None None 116254019 Common prfA peptide chain release factor 1 RL4282 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 116253975 Common - hypothetical protein RL4238 14 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 116253406 Common pssT putative polysaccharide export protein RL3665 16 None None None 116251836 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A RL2076 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 116250863 Common - hypothetical protein RL1091 11 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 116250490 Common flaA1 putative flagellin A protein RL0718 84 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116252879 Common - replicative DNA helicase RL3138 123 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 116252561 Common fabF1 3-oxoacyl-(acyl carrier protein) synthase II RL2814 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116251799 Common - putative HesB family protein RL2039 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 116254130 Common - putative transcriptional regulator RL4397 84 COG0789 SoxR, Predicted transcriptional regulators Transcription 116251764 Common dctP putative C4-dicarboxylate-binding periplasmic protein precursor RL2001 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 116250315 Common - putative transmembrane component of ABC transporter RL0543 228 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 116251759 Common - putative solute-binding component of ABC transporter RL1996 82 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250247 Common - hypothetical protein RL0476 26 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 116251026 Nonpathogen - hypothetical protein RL1259 6 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 116251790 Nonpathogen - hypothetical protein RL2029 1 None None None 116250995 Common - putative TetR family transcriptional regulator RL1228 41 COG1309 AcrR, Transcriptional regulator Transcription 116250389 Common - Maf-like protein RL0617 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 116251596 Common - putative oxidoreductase RL1830 185 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116251665 Nonpathogen - hypothetical protein RL1900 1 None None None 116252602 Common - putative LysR family transcriptional regulatory protein RL2855 172 COG0583 LysR, Transcriptional regulator Transcription 116251692 Nonpathogen - hypothetical protein RL1928 4 None None None 116252236 Common - hypothetical protein RL2489A 15 COG2261 COG2261, Predicted membrane protein Function unknown 116250766 Common matC putative transmembrane dicarboxylate carrier protein RL0992 14 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 116250169 Common - putative nifU iron-sulphur cluster scaffold protein RL0400 92 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 116252547 Common - hypothetical protein RL2800 4 None None None 116252186 Common copC putative copper oxidase RL2433 32 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 116252654 Common - hypothetical protein RL2907 14 COG4947 COG4947, Uncharacterized protein conserved in bacteria Function unknown 116250183 Common - putative carbon monooxide dehydrogenase related protein RL0414 41 COG3427 COG3427, Uncharacterized conserved protein Function unknown 116252002 Common - dihydrolipoamide dehydrogenase RL2246 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 116249823 Common - putative two-component response regulator transcriptional regulatory protein RL0057 218 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 116249967 Common cdd cytidine deaminase RL0200 117 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 116253105 Common - hypothetical protein RL3364 2 None None None 116252533 Common - putative transmembrane permease component of ABC transporter RL2786 181 COG1511 COG1511, Predicted membrane protein Function unknown 116250814 Common - putative oxidoreductase/monooxygenase RL1041 22 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 116250557 Common - putative transmembrane protein RL0785 19 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 116252585 Common - hypothetical protein RL2838 2 None None None 116252893 Common - hypothetical protein RL3151 3 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 116252522 Common - putative AsnC family transcriptional regulator RL2776 140 COG1522 Lrp, Transcriptional regulators Transcription 116253018 Common - putative 3-demethylubiquinone-9 3-methyltransferase family protein RL3275 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 116251462 Nonpathogen - hypothetical protein RL1696 5 None None None 116253439 Common hmuU transmembrane permease component of haem ABC transporter RL3699 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 116252117 Common - putative ATP-binding component of ABC transporter RL2365 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 116252866 Common - putative esterase RL3124 32 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 116254363 Common - putative FMN reductase RL4637 42 COG0431 COG0431, Predicted flavoprotein General function prediction only 116252722 Common - putative transmembrane component of ABC transporter RL2976 28 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 116253170 Common trxB putative thioredoxin reductase RL3428 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 116250439 Common - hypothetical protein RL0667 7 None None None 116252297 Common - putative transmembrane cationic transporter RL2551 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 116254458 Common holA DNA polymerase III subunit delta RL4734 35 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 116250828 Common - hypothetical protein RL1055 25 COG4898 COG4898, Uncharacterized protein conserved in bacteria Function unknown 116251801 Common argS arginyl-tRNA synthetase RL2041 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250407 Common - putative ATP-binding component of ABC transporter RL0635 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116250463 Common cheB chemotaxis-specific methylesterase RL0691 209 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 116250186 Common ihfB integration host factor subunit beta RL0417 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 116250114 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase RL0346 183 COG0756 Dut, dUTPase Nucleotide transport and metabolism 116249869 Common - putative MerR family transcriptional regulator RL0103 87 COG0789 SoxR, Predicted transcriptional regulators Transcription 116252137 Common - hypothetical protein RL2385 38 COG2938 COG2938, Uncharacterized conserved protein Function unknown 116252888 Common - putative transmembrane transporter RL3147 28 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252024 Nonpathogen - putative transmembrane protein RL2268 1 None None None 116250821 Common - putative transmembrane component of ABC transporter RL1048 179 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 116251271 Common - DNA-directed RNA polymerase subunit omega RL1505 113 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 116252802 Common - putative cell envelope protein RL3058 40 COG5361 COG5361, Uncharacterized conserved protein Function unknown 116252801 Common - putative AraC family transcriptional regulator RL3057 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250219 Common - hypothetical protein RL0450 3 None None None 116253830 Common - putative two component response regulator transcriptional regulatory protein RL4093 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116250275 Common pgi glucose-6-phosphate isomerase RL0504 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 116252518 Common - putative dehydrogenase/reductase RL2772 194 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 116252877 Common ugpB putative glycerol-3-phosphate-binding periplasmic protein precursor RL3135 97 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252555 Common - putative transcriptional regulatory protein RL2808 25 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250540 Common acsA acetyl-CoA synthetase RL0768 201 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 116253726 Nonpathogen - hypothetical protein RL3987 7 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 116250164 Common miaB putative MiaB protein (methylthiolation of isopentenylated A37 derivatives in rRNA) RL0395 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 116252975 Common - hypothetical protein RL3233 40 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 116253951 Common mtlK putative mannitol 2-dehydrogenase RL4214 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 116252305 Common - putative acetyltransferase RL2559 92 COG2153 ElaA, Predicted acyltransferase General function prediction only 116252755 Common - hypothetical protein RL3010 5 None None None 116250331 Common - putative epimerase RL0560 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116250932 Common - hypothetical protein RL1164 9 None None None 116253457 Common - hypothetical protein RL3717 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 116252008 Common - hypothetical protein RL2252 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 116254025 Common grxC putative glutaredoxin RL4289 117 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 116254285 Common - hypothetical protein RL4558 43 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 116251203 Common cycJ cytochrome c-type biogenesis protein CcmE RL1437 95 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 116251847 Common aat leucyl/phenylalanyl-tRNA--protein transferase RL2087 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 116250144 Common dnaA chromosomal replication initiation protein RL0375 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 116250074 Common - putative isochorismatase family protein RL0306 84 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 116249834 Common - putative component of ABC transporter RL0068 77 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 116250258 Common fucU putative fucose uptake protein RL0487 29 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 116252054 Common - putative dioxygenase RL2298 107 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 116252965 Common - putative nodulation protein RL3223 49 COG0789 SoxR, Predicted transcriptional regulators Transcription 116253500 Common - putative two-component response regulator transcriptional regulatory protein RL3759 94 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 116252574 Common - hypothetical protein RL2827 16 None None None 116250429 Common - conserved hypothetical AIR family protein RL0657 101 COG2144 COG2144, Selenophosphate synthetase-related proteins General function prediction only 116253940 Common talB transaldolase B RL4203 153 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 116253224 Common - putative MaoC family protein RL3482 47 COG2030 MaoC, Acyl dehydratase Lipid metabolism 116253720 Common - hypothetical protein RL3981 29 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 116253148 Common - putative biotin synthesis protein RL3406 57 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 116252388 Common - hypothetical protein RL2642 10 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 116250988 Common - putative HTH family transcriptional regulator RL1221 63 COG0640 ArsR, Predicted transcriptional regulators Transcription 116251621 Nonpathogen - hypothetical protein RL1855 5 None None None 116253981 Common - putative transmembrane component of ABC transporter RL4244 177 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116251925 Common - putative DNA-invertase RL2167 133 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 116251069 Common - putative MarR family transcriptional regulator RL1301A 121 COG1846 MarR, Transcriptional regulators Transcription 116252309 Common pccB putative propionyl-CoA carboxylase protein RL2563 215 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 116251156 Common - hypothetical protein RL1388 10 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 116250718 Common - putative LemA like outer membrane protein RL0944 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 116250699 Common atpB F0F1 ATP synthase subunit A RL0925 157 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 116250191 Common rpoN RNA polymerase factor sigma-54 RL0422 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 116250826 Common - putative exported endoribonuclease family protein RL1053 70 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116253843 Common cya putative adenylate/guanylate cyclase RL4106 69 COG5616 COG5616, Predicted integral membrane protein Function unknown 116251975 Common - hypothetical protein RL2219 19 None None None 116253938 Common - putative DoxD family transmembrane protein RL4201 24 COG2259 COG2259, Predicted membrane protein Function unknown 116250408 Nonpathogen - putative transmembrane protein RL0636 2 None None None 116253918 Common - putative TetR family transcriptional regulator RL4181 118 COG1309 AcrR, Transcriptional regulator Transcription 116252438 Common - putative ATP-binding component of ABC transporter RL2691 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116253491 Common - putative transmembrane component of ABC transporter RL3750 157 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 116250153 Common hspH putative small heat shock protein RL0384 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 116251102 Common - putative TetR family transcriptional regulator RL1334 91 COG1309 AcrR, Transcriptional regulator Transcription 116253902 Common - putative glyoxalase family protein RL4165 4 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 116252511 Common - hypothetical protein RL2765 21 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116251878 Nonpathogen - putative transmembrane protein RL2118 1 None None None 116254069 Common - hypothetical protein RL4334 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 116250103 Common - putative tetrapyrrole-methylase protein RL0335 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 116253371 Common - putative sugar decarboxylase RL3628 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116250068 Common - putative acetyltransferase RL0300 26 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116253242 Common - hypothetical protein RL3500 61 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 116253917 Common - putative HlyD secretion protein RL4180 149 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116254077 Common - putative transmembrane protein RL4342 104 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116252716 Nonpathogen - putative transmembrane protein RL2969 1 None None None 116252864 Common gst putative glutathione S-transferase RL3122 76 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251652 Nonpathogen - putative transmembrane protein RL1887 3 None None None 116252360 Nonpathogen - hypothetical protein RL2614 11 None None None 116251460 Common - putative aldo-keto reductase RL1694 193 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253408 Common - putative UDP-glucose 6-dehydrogenase RL3667 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 116250203 Common truA tRNA pseudouridine synthase A RL0434 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 116253465 Common - putative RND family transmembrane transporter RL3725 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116250420 Common - hypothetical protein RL0648 18 COG3822 COG3822, ABC-type sugar transport system, auxiliary component General function prediction only 116250678 Common lpxK tetraacyldisaccharide 4'-kinase RL0904 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 116253235 Common - hypothetical protein RL3493 9 None None None 116253669 Common - hypothetical protein RL3929 4 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116252501 Common - putative transmembrane permease component of ABC transporter RL2755 175 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 116250584 Common - putative glycosyltransferase RL0811A 49 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116249785 Common - hypothetical protein RL0019 148 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 116252200 Common - putative solute-binding component of ABC transporter RL2448 86 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251713 Common - putative universal stress family protein RL1949 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116251671 Nonpathogen - putative transmembrane protein RL1907 5 None None None 116253931 Common - putative succinatesemialdehyde dehydrogenase RL4194 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116253580 Common - putative GntR family transcriptional regulator RL3839 103 COG2186 FadR, Transcriptional regulators Transcription 116251885 Nonpathogen - hypothetical protein RL2125 1 None None None 116250593 Common - putative O-antigen transporter RL0821 18 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116250194 Common ptsN putative nitrogen regulatory IIA protein RL0425 138 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 116250792 Common tldD putative regulator RL1019 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 116251177 Common - hypothetical protein RL1409 9 None None None 116252090 Common - putative GntR family transcriptional regulator RL2337 133 COG2186 FadR, Transcriptional regulators Transcription 116249878 Common - putative transmembrane protein RL0112 91 COG1434 COG1434, Uncharacterized conserved protein Function unknown 116250961 Common - putative short-chain reductase RL1193 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251127 Common - hypothetical protein RL1359 45 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 116251155 Common - hypothetical protein RL1387 13 COG5447 COG5447, Uncharacterized conserved protein Function unknown 116251488 Common - hypothetical protein RL1722 3 None None None 116251610 Common - putative LysR family transcriptional regulator RL1844 128 COG0583 LysR, Transcriptional regulator Transcription 116253609 Common rLuB putative ribosomal large subunit pseudouridine synthase B RL3869 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 116250910 Common - putative ECF sigma factor RL1138 163 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116251548 Common rpmC 50S ribosomal protein L29 RL1782 168 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 116252692 Nonpathogen - hypothetical protein RL2945 2 None None None 116251243 Nonpathogen - putative transmembrane protein RL1477 1 None None None 116250498 Common - hypothetical protein RL0726 44 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 116251953 Nonpathogen - hypothetical protein RL2196 3 None None None 116253661 Nonpathogen - putative transmembrane protein RL3921 1 None None None 116253557 Common - putative polysaccharide export protein RL3816 88 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116252531 Common - putative LysR family transcriptional regulator RL2784 186 COG0583 LysR, Transcriptional regulator Transcription 116250901 Nonpathogen - hypothetical protein RL1129 1 None None None 116253688 Nonpathogen - hypothetical protein RL3948 1 None None None 116250872 Common hsdR type I restriction enzyme EcoKI subunit R RL1100 97 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 116252170 Common - putative solute-binding component of ABC transporter RL2418 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116254436 Common - hypothetical protein RL4712 5 None None None 116251732 Nonpathogen - hypothetical protein RL1968 1 None None None 116250956 Common - putative kinase RL1188 47 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 116252508 Common - hypothetical protein RL2762 28 COG5649 COG5649, Uncharacterized conserved protein Function unknown 116254165 Common citM dihydrolipoamide acetyltransferase RL4433 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 116253537 Common - putative transmembrane component of ABC transporter RL3796 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251915 Nonpathogen - hypothetical protein RL2157 1 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 116252193 Common - putative adenylate cyclase RL2441 109 COG3899 COG3899, Predicted ATPase General function prediction only 116250795 Common coxA putative cytochrome c oxidase polypeptide I (cytochrome aa3 subunit 1) RL1022 171 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 116250692 Common - putative IclR family transcriptional regulator RL0918 116 COG1414 IclR, Transcriptional regulator Transcription 116251994 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase RL2238 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 116254245 Nonpathogen - hypothetical protein RL4518 1 None None None 116251675 Common - putative arylsulfatase RL1911 85 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116253784 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit RL4045 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 116252917 Common zur putative zinc uptake regulation protein RL3175 87 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 116253829 Common - putative N-formylglutamate deformylase RL4092 58 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 116250127 Common fabG short chain dehydrogenase RL0358 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250484 Common flgI flagellar basal body P-ring protein RL0712 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 116251351 Common moaD putative molybdopterin converting factor subunit RL1585 49 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 116253450 Common - putative rhodanese protein RL3710 46 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 116251070 Common - putative OsmC-like organic hydroperoxide resistance protein RL1302 97 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116251363 Common - putative transmembrane protein RL1597 188 COG0628 PerM, Predicted permease General function prediction only 116252336 Common - putative transmembrane protein RL2590 32 COG3164 COG3164, Predicted membrane protein Function unknown 116250638 Common glcE putative glycolate oxidase subunit RL0865 161 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 116253705 Common ftsH putative cell division protein FtsH RL3965 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 116252457 Common - hypothetical protein RL2710 51 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 116253602 Common - putative solute-binding component of ABC transporter RL3862 98 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252444 Common - hypothetical protein RL2697 12 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 116254051 Common - putative transmembrane protein RL4316 15 None None None 116251553 Common rpsN 30S ribosomal protein S14 RL1787 204 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 116253382 Common - putative transcriptional regulator RL3639 40 COG1396 HipB, Predicted transcriptional regulators Transcription 116254278 Common trmD tRNA (guanine-N(1)-)-methyltransferase RL4551 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 116250773 Common - putative hydrolase RL1000 143 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116253023 Common - putative riboflavin biosynthesis protein RL3280 50 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116253824 Common - putative LysR family transcriptional regulator RL4087 167 COG0583 LysR, Transcriptional regulator Transcription 116251898 Nonpathogen - hypothetical protein RL2139 3 None None None 116253599 Common - putative ATP-binding component of ABC transporter RL3859 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116251165 Common - putative exopolysaccharide synthesis protein RL1397 43 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 116252763 Common - putative transmembrane b-type cytochrome protein RL3018 44 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 116253628 Common hipO putative hippurate hydrolase RL3888 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 116250536 Common - probable putrescine transport atp-binding protein RL0764 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116249883 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I RL0117 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116253547 Common - putative transmembrane component of ABC transporter protein RL3806 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116252135 Common - hypothetical protein RL2383 81 COG2928 COG2928, Uncharacterized conserved protein Function unknown 116249911 Common - hypothetical protein RL0144 60 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 116251860 Common - hypothetical protein RL2100 25 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 116251814 Common - putative Sec translocase associated protein RL2054 43 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 116252663 Common - putative siderophore interacting protein RL2916 61 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 116253860 Common soxA putative sarcosine oxidase alpha subunit RL4123 182 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 116253760 Common - hypothetical protein RL4021 46 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 116254000 Common - putative MerR family transcriptional regulator RL4263 139 COG0789 SoxR, Predicted transcriptional regulators Transcription 116250043 Common - hypothetical protein RL0275 7 None None None 116252842 Nonpathogen - putative transmembrane protein RL3101 1 COG4709 COG4709, Predicted membrane protein Function unknown 116251186 Common - utative AraC family transcriptional regulator RL1420 117 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116253901 Common - hypothetical protein RL4164 7 COG5607 COG5607, Uncharacterized conserved protein Function unknown 116251659 Nonpathogen - hypothetical protein RL1894 1 None None None 116250806 Common - hypothetical protein RL1033 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 116251146 Common mrpG putative monovalent cation/H+ antiporter subunit G RL1378 38 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 116251233 Common - putative aminotransferase RL1467 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 116252683 Common - putative transmembrane protein RL2936 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 116254349 Nonpathogen - putative transmembrane protein RL4623 12 None None None 116253473 Common ureY putative urease operon 23 kda accessory protein (orf6) RL3732 5 None None None 116254398 Nonpathogen - hypothetical protein RL4673 1 None None None 116250293 Common - hypothetical protein RL0522 95 COG1802 GntR, Transcriptional regulators Transcription 116249902 Common - hypothetical protein RL0135 61 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 116252627 Common - putative GGDEF domain and response regulator two component regulatory protein RL2880 216 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 116253008 Common - putative AraC family transcriptional regulator RL3265 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116251223 Common - putative electron transfer flavoprotein-ubiquinone oxidoreductase RL1457 112 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 116251481 Common birA putative biotin transcriptional regulator bifunctional protein RL1715 210 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 116250457 Common - putative chemoreceptor protein RL0685 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116252524 Common - putative exopolysaccharide biosynthesis protein RL2778 26 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 116249918 Common dnaJ putative chaperone protein RL0151 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 116251269 Common smpB SsrA-binding protein RL1503 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 116253055 Common - hypothetical protein RL3314 15 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 116252201 Common - putative ATP-binding component of ABC transporter RL2449 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116253735 Nonpathogen - putative DoxD family transmembrane protein RL3996 2 COG2259 COG2259, Predicted membrane protein Function unknown 116253352 Common - hypothetical protein RL3609 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 116251571 Common - putative transmembrane protein RL1805 25 COG3339 COG3339, Uncharacterized conserved protein Function unknown 116251648 Common hspF putative small heat shock protein RL1883 149 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 116249956 Common - putative 2-hydroxyacid dehydrogenase RL0189 225 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 116251767 Nonpathogen - hypothetical protein RL2004 1 None None None 116253995 Common nrdF ribonucleotide-diphosphate reductase subunit beta RL4258 145 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 116250044 Common - putative acetyltransferase RL0276 89 COG0456 RimI, Acetyltransferases General function prediction only 116251472 Common - conserved hypothetical protein in NADH-ubiquinone oxidoreductase region RL1706 25 COG3743 COG3743, Uncharacterized conserved protein Function unknown 116254123 Common fdhD formate dehydrogenase accessory protein RL4390 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 116253076 Common - putative lipase RL3335 92 COG2267 PldB, Lysophospholipase Lipid metabolism 116254111 Common - putative LacI family transcriptional regulator RL4378 128 COG1609 PurR, Transcriptional regulators Transcription 116250017 Common - hypothetical protein RL0249 3 None None None 116251830 Common - putative TetR family transcriptional regulator RL2070 3 COG1309 AcrR, Transcriptional regulator Transcription 116252935 Common - putative transmembrane component of ABC transporter RL3193 216 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 116250925 Common - putative two component sensor histidine kinase transcriptional regulator RL1156 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116249897 Common - hypothetical protein RL0131 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 116253001 Common - hypothetical protein RL3258 11 None None None 116250548 Common iolA malonic semialdehyde oxidative decarboxylase RL0776 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116250744 Common - putative FtsJ cell division/haemolysin-like protein RL0970 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 116253328 Common - hypothetical protein RL3585 25 COG2361 COG2361, Uncharacterized conserved protein Function unknown 116252903 Common - putative LysR family transcriptional regulator RL3161 181 COG0583 LysR, Transcriptional regulator Transcription 116251451 Common - putative ATP-binding component of ABC transporter RL1685 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 116252599 Common - putative metapyrocatechase RL2852 34 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 116251930 Nonpathogen - hypothetical protein RL2173 1 None None None 116252891 Nonpathogen - putative adenylate cyclase RL3149a 3 None None None 116253896 Common - putative transmembrane protein RL4159 38 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 116253846 Common - putative transglutaminase family protein RL4109 86 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 116250253 Common - putative TetR family transcriptional regulator RL0482 91 COG1309 AcrR, Transcriptional regulator Transcription 116251372 Common - putative esterase (beta-lactamase family) RL1606 144 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 116252831 Common - putative GGDEF/EAL sensory box protein RL3088 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116249875 Common - hypothetical protein RL0109 17 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 116251722 Common - putative TetR family transcriptional regulator RL1958 63 COG1309 AcrR, Transcriptional regulator Transcription 116249797 Common - S-adenosyl-L-homocysteine hydrolase RL0031 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 116250663 Common ileS isoleucyl-tRNA synthetase RL0889 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116252613 Common - putative transmembrane sulfate transporter RL2866 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 116254425 Common - hypothetical protein RL4701 23 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 116250620 Common guaB inositol-5-monophosphate dehydrogenase RL0847 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 116252497 Common - putative ATP-binding component of ABC transporter RL2751 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116253378 Nonpathogen - hypothetical protein RL3635 1 None None None 116251096 Common - putative LysR family transcriptional regulator RL1328 178 COG0583 LysR, Transcriptional regulator Transcription 116250783 Common gpmB putative phosphoglycerate mutase RL1010 146 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116252331 Common nodX putative nodulation protein X (probable sugar acetylase) RL2585 61 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116254172 Common - hypothetical protein RL4440 99 COG1485 COG1485, Predicted ATPase General function prediction only 116252289 Common - hypothetical protein RL2543 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 116250131 Common - putative MFS family transmembrane transport protein RL0362 93 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116249779 Common - putative oxidoreductase RL0013 46 COG0778 NfnB, Nitroreductase Energy production and conversion 116251388 Common ribC riboflavin synthase subunit alpha RL1622 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 116253411 Common - hypothetical protein RL3670 2 None None None 116250625 Common - hypothetical protein RL0852 3 None None None 116252351 Common - putative GGDEF/EAL sensory box protein RL2605 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116250685 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL0911 211 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 116251310 Common - putative glycosyl transferase RL1544 41 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 116252819 Common - conserved hypothetical protein, possible pseudogene RL3075 40 None None None 116253446 Common - putative two-component regulator sensor histidine kinase transcriptional regulatory protein RL3706 29 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 116250433 Common - hypothetical protein RL0661 17 None None None 116252738 Common gstA putative glutathione S-transferase RL2993 89 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251261 Common iolC putative myo-inositol catabolism protein RL1495 140 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 116253550 Common - putative solute-binding component of ABC transporter RL3809 116 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253563 Nonpathogen - putative glycosyl transferase RL3822 6 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116251641 Common adh putative alcohol dehydrogenase RL1876 203 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 116253614 Common rmeA putative RND family transporter RL3874 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116249828 Common - hypothetical protein RL0062 23 None None None 116250414 Common - putative PfkB family sugar kinase RL0642 184 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116252209 Common - putative LysR family transcriptional regulator RL2458 172 COG0583 LysR, Transcriptional regulator Transcription 116252700 Common - putative adenylate/guanylate cyclase RL2953 80 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116250099 Common pyrF orotidine 5'-phosphate decarboxylase RL0331 163 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 116250729 Common - putative MipA family outer membrane scaffold protein RL0955 28 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 116252094 Common - putative ABC transporter component RL2341 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250090 Common - putative iron-regulated protein RL0322 35 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 116250010 Common - putative O antigen biosynthesis protein RL0242 114 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116249994 Common - putative transmembrane component of ABC transporter RL0227 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116253207 Common - hypothetical protein RL3465 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 116252263 Nonpathogen - hypothetical protein RL2517 4 None None None 116253758 Common - hypothetical protein RL4019 66 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 116249936 Common - putative transposase for insertion element family protein RL0169 107 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 116252474 Common - putative transmembrane protein RL2728 52 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 116250179 Common lspA putative transmembrane lipoprotein signal peptidase RL0410 201 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116252450 Common fumA utative fumarate hydratase class I, aerobic RL2703 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 116252213 Common - hypothetical protein RL2462 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 116251211 Common - putative two component sensor histidine kinase transcriptional regulatory protein RL1445 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251703 Nonpathogen - hypothetical protein RL1939 1 None None None 116252838 Common arcB ornithine cyclodeaminase RL3095 82 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 116251064 Common - hypothetical protein RL1297 68 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116250172 Common - hypothetical protein RL0403 35 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116250681 Common - putative ATP-binding component of ABC transporter RL0907 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116250617 Common - hypothetical protein RL0844 53 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 116253949 Common araB putative ribulokinase RL4212 147 COG1069 AraB, Ribulose kinase Energy production and conversion 116252031 Common - hypothetical protein RL2275 14 None None None 116252590 Common - putative transmembrane component of ABC transporter RL2843 154 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 116254133 Common - putative transmembrane component of ABC transporter RL4400 130 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 116250757 Common - putative solute-binding component of ABC transporter RL0983 40 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116254146 Common - putative component of ABC transporter RL4414 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250061 Common - putative methylated-DNA--protein-cysteine methyltransferase RL0293 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 116251981 Common uppS putative undecaprenyl pyrophosphate synthetase RL2225 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 116250214 Common argB acetylglutamate kinase RL0445 225 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 116251033 Nonpathogen - hypothetical protein RL1266 8 None None None 116253298 Common - hypothetical protein RL3556 11 None None None 116251566 Common - putative transmembrane protein RL1800 12 None None None 116253196 Common - putative two-component response regulator transcriptional regulatory protein RL3454 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116252439 Common - putative DAHP synthetase protein RL2692 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 116252811 Common - putative two component response regulator transcriptional regulatory protein RL3067 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116254232 Common - hypothetical protein RL4503 62 COG1872 COG1872, Uncharacterized conserved protein Function unknown 116249946 Common gpmA phosphoglyceromutase RL0179 176 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 116250577 Nonpathogen - putative transmembrane protein RL0806 1 None None None 116250803 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase RL1030 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 116252656 Common - putative NAD(P)H dehydrogenase RL2909 86 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 116253185 Common - aspartate aminotransferase RL3443 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116252499 Common - putative solute-binding component of ABC transporter RL2753 183 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116253151 Common - hypothetical protein RL3409 6 None None None 116254353 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase RL4627 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 116252143 Common - hypothetical protein RL2391 42 COG3785 COG3785, Uncharacterized conserved protein Function unknown 116251001 Common - putative glyxoylase RL1234 47 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 116250243 Common - putative TetR family transcriptional regulator RL0472 32 COG1309 AcrR, Transcriptional regulator Transcription 116251863 Common - hypothetical protein RL2103 89 COG1430 COG1430, Uncharacterized conserved protein Function unknown 116253697 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase RL3957 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 116254334 Common - hypothetical protein RL4608 11 None None None 116249767 Common - hypothetical protein RL0001 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 116254169 Nonpathogen - hypothetical protein RL4437 4 None None None 116252631 Common arsC1 putative arsenate reductase RL2884 119 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 116251374 Common - putative transmembrane protein RL1608 6 None None None 116251868 Common - hypothetical protein RL2107 60 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 116254108 Common - putative transmembrane component of ABC transporter RL4375 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116254418 Common - dinucleoside polyphosphate hydrolase RL4694 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 116254375 Common - putative transmembrane component of ABC transporter RL4650 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251511 Common - putative ATP-binding component of ABC transporter RL1745 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116252454 Common - hypothetical protein RL2707 24 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 116254333 Common - putative transmembrane component of ABC transporter RL4607 98 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 116252325 Common sufD putative iron-sulfur cluster assembly protein RL2579 170 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 116252619 Nonpathogen - hypothetical protein RL2872 2 None None None 116254255 Common - putative 2'-5' RNA ligase RL4528 124 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 116251969 Common clpA putative ATP-dependent Clp protease ATP-binding subunit RL2213 233 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 116254160 Common - putative transmembrane cytochrome b562 RL4428 74 COG3038 CybB, Cytochrome B561 Energy production and conversion 116252740 Common - hypothetical protein RL2995 16 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116253690 Common - putative phage-related protein RL3950 11 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 116249805 Common - putative alkylated DNA repair protein RL0039 60 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 116254292 Common glnB putative nitrogen regulatory protein PII RL4565 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 116252229 Nonpathogen - hypothetical protein RL2482 2 None None None 116254308 Common fbpC putative ferric cations import ATP-binding protein FbpC RL4582 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116250453 Nonpathogen - putative transmembrane protein RL0681 1 None None None 116250509 Common - hypothetical protein RL0737 3 None None None 116254275 Common - chorismate mutase RL4548 58 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 116250262 Common - putative ATP-binding component of ABC transporter RL0491 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116252085 Common - hypothetical protein RL2332 67 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116253015 Common - hypothetical protein RL3272 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 116251533 Common rpoC DNA-directed RNA polymerase subunit beta' RL1767 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 116251138 Common msrB methionine sulfoxide reductase B RL1370 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 116253819 Common - putative peptidoglycan binding protein RL4082 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 116252779 Common glyA hypothetical protein RL3034 8 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 116253525 Common - putative efflux pump protein RL3784 150 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116254441 Common - putative sensory box GGDEF transmembrane protein RL4717 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116254431 Common leuB 3-isopropylmalate dehydrogenase RL4707 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 116253584 Common - putative transmembrane component of ABC transporter RL3843 166 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116250614 Common - hypothetical protein RL0841 2 None None None 116250095 Common - putative glutathione S-transferase RL0327 58 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251933 Common - hypothetical protein RL2176 23 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 116251792 Nonpathogen - hypothetical protein RL2032 1 None None None 116252986 Common ilvH acetolactate synthase 3 regulatory subunit RL3244 189 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 116252396 Common folC putative dihydroxypteroate synthase RL2650 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 116253058 Common - putative N-methyl-l-tryptophan oxidase RL3317 11 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116250998 Common - short chain dehydrogenase RL1231 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116254139 Common atpD F0F1 ATP synthase subunit beta RL4407 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 116253595 Common - putative short-chain dehydrogenase/reductase RL3854 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252795 Common - putative transmembrane component of ABC transporter RL3051 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 116250644 Common tag putative DNA-3-methyladenine glycosylase I RL0871 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 116252106 Common - putative LysR family transcriptional regulator RL2354 136 COG0583 LysR, Transcriptional regulator Transcription 116252644 Common - putative transmembrane component of ABC transporter RL2897 172 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116251946 Nonpathogen - hypothetical protein RL2189 1 None None None 116252358 Common purL phosphoribosylformylglycinamidine synthase II RL2612 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 116250983 Common - hypothetical protein RL1216 5 None None None 116253535 Common - putative solute-binding component of ABC transporter RL3794 132 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116250581 Common - putative polysaccharide synthesis RL0810 153 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116253367 Common - putative solute-binding component of ABC transporter RL3624 107 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 116254400 Common rplU 50S ribosomal protein L21 RL4676 204 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 116250539 Common - hypothetical protein RL0767 20 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 116249856 Common - putative TetR family transcriptional regulator RL0090 117 COG1309 AcrR, Transcriptional regulator Transcription 116252607 Common - hypothetical protein RL2860 18 None None None 116251584 Common - hypothetical protein RL1818 52 COG2128 COG2128, Uncharacterized conserved protein Function unknown 116254119 Common cheW putative chemotaxis protein RL4386 134 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 116249781 Common - putative glutathione-S-transferase RL0015 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116250117 Common - putative glutathione-S-transferase RL0349 58 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116250755 Common - putative transmembrane component of ABC transporter RL0981 167 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 116251008 Nonpathogen - putative transmembrane protein RL1241 1 None None None 116253287 Common - putative transmembrane component of ABC transporter protein RL3545 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116249892 Common - hypothetical protein RL0126 37 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 116250640 Nonpathogen - hypothetical protein RL0867 2 None None None 116249970 Common deoA thymidine phosphorylase RL0203 127 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 116252955 Common - putative tetracycline resistance protein RL3213 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 116252488 Common - hypothetical protein RL2742 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116254202 Common aspC aromatic amino acid aminotransferase RL4471 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116251479 Common nuoM NADH dehydrogenase subunit M RL1713 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 116252847 Common - putative LysR family transcriptional regulator RL3106 170 COG0583 LysR, Transcriptional regulator Transcription 116250502 Common flgL flagellar hook-associated protein FlgL RL0730 27 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116250159 Common - putative HTH-type transcriptional regulator RL0390 40 COG1396 HipB, Predicted transcriptional regulators Transcription 116254104 Common - hypothetical protein RL4371 3 None None None 116253771 Common - putative sensory transducer methyl-acccepting chemotaxis protein RL4032 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116250890 Nonpathogen - hypothetical protein RL1118 1 None None None 116253415 Common noeK putative phosphomannomutase RL3674 236 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 116252177 Common - putative MarR family transcriptional regulator RL2425 52 COG1846 MarR, Transcriptional regulators Transcription 116254079 Common - putative transmembrane protein RL4344 58 COG1738 COG1738, Uncharacterized conserved protein Function unknown 116250833 Common - putative ribosomal-protein-alanine acetyltransferase RL1060 125 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116250899 Common - putative adenylate cyclase RL1127 104 COG5616 COG5616, Predicted integral membrane protein Function unknown 116251834 Common - metal-dependent hydrolase RL2074 89 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 116251528 Common rplA 50S ribosomal protein L1 RL1762 241 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 116251630 Common - putative hydrolase RL1865 68 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 116253231 Common - hypothetical protein RL3489 7 None None None 116251413 Common celB putative cellulose synthase protein RL1647 8 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 116252832 Nonpathogen - hypothetical protein RL3089 4 None None None 116251574 Common - hypothetical protein RL1808 6 None None None 116252481 Common - putative aldo-keto reductase RL2735 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116252571 Common cobA putative Uroporphyrin-III C-methyltransferase RL2824 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 116249788 Common trpA tryptophan synthase subunit alpha RL0022 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 116252260 Common - hypothetical protein RL2514 6 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 116250359 Common - putative peptidoglycan binding protein RL0588 104 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 116253648 Common - putative transmembrane component of ABC transporter RL3908 142 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 116250350 Common - hypothetical protein RL0579 81 COG2128 COG2128, Uncharacterized conserved protein Function unknown 116251601 Common - putative two component response regulator transcriptional regulatory protein RL1835 188 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116254315 Common - hypothetical protein RL4589 30 COG1522 Lrp, Transcriptional regulators Transcription 116253739 Common - putative ArsR family transcriptional regulator RL4000 38 COG0640 ArsR, Predicted transcriptional regulators Transcription 116252047 Common - hypothetical protein RL2291 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 116250374 Common - aspartate aminotransferase RL0603 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116253294 Common - putative MarR family transcriptional regulator RL3552 80 COG1846 MarR, Transcriptional regulators Transcription 116250846 Common - hypothetical protein RL1073 17 None None None 116251296 Common - putative transmembrane protein RL1530 80 COG1742 COG1742, Uncharacterized conserved protein Function unknown 116252728 Common - putative TetR family transcriptional regulator RL2982 32 None None None 116252412 Common - putative RND family multidrug efflux transporter RL2666 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116250518 Common aglF putative alpha-glucoside transport system transmembrane component of ABC transporter RL0746 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250500 Common flgE flagellar hook protein FlgE RL0728 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 116250278 Common manB putative mannosidase RL0507 46 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 116253270 Common - putative LuxR/GerE family transcriptional regulatory protein RL3528 71 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116249978 Common pilA putative pilus subunit protein RL0211 32 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 116253853 Common glgC glucose-1-phosphate adenylyltransferase RL4116 157 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 116249811 Nonpathogen - hypothetical protein RL0045 1 None None None 116251562 Common rpsM 30S ribosomal protein S13 RL1796 243 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 116250067 Common - putative LysR family transcriptional regulator RL0299 182 COG0583 LysR, Transcriptional regulator Transcription 116251932 Nonpathogen - hypothetical protein RL2175 1 None None None 116254405 Common obgE GTPase ObgE RL4681 249 COG0536 Obg, Predicted GTPase General function prediction only 116253467 Common ureG putative urease accessory protein RL3727 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 116249926 Common - putative MarR family transcriptional regulator protein RL0159 110 COG1846 MarR, Transcriptional regulators Transcription 116250059 Common - putative arginine catabolism protein RL0291 26 COG3608 COG3608, Predicted deacylase General function prediction only 116252224 Common dacF putative penicillin-binding protein RL2477 147 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116252286 Common - putative transmembrane anchored protein RL2540 9 None None None 116251134 Common uspF putative universal stress protein F RL1366 33 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 116250121 Common - putative exported peptidase RL0352 38 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 116251690 Common - hypothetical protein RL1926 26 COG5361 COG5361, Uncharacterized conserved protein Function unknown 116252757 Common - hypothetical protein RL3012 2 None None None 116252804 Common - hypothetical protein RL3060 61 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116253326 Common - putative purine catabolism protein RL3583 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 116253779 Common thiE thiamine-phosphate pyrophosphorylase RL4040 43 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 116251753 Common nirD putative 2Fe-2S rieske nitrite reductase small subunit RL1990 84 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 116251569 Common ilvD dihydroxy-acid dehydratase RL1803 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 116253267 Common fhs putative formate--tetrahydrofolate ligase RL3525 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 116253341 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL3598 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116252947 Common ilvC ketol-acid reductoisomerase RL3205 211 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 116251506 Common - putative acyl CoA-like DNA repair protein RL1740 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 116254174 Nonpathogen - hypothetical protein RL4442 1 None None None 116251197 Common - putative transmembrane MFS family permease RL1431 36 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250716 Common - putative transmembrane protein RL0942 6 None None None 116251316 Common - putative alanine racemase RL1550 196 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 116252744 Nonpathogen - putative glyoxylase RL2999 9 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116252248 Common - putative NADH oxidase RL2502 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 116251028 Common cysD sulfate adenylyltransferase subunit 2 RL1261 127 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 116250727 Common cfa putative cyclopropane-fatty-acyl-phospholipid synthase RL0953 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 116251911 Common - hypothetical protein RL2153 3 None None None 116251803 Common nagZ putative beta-hexosaminidase/N-acetyl-beta-glucosaminidase RL2043 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 116251504 Common pyrC dihydroorotase RL1738 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 116254112 Common hemA 5-aminolevulinate synthase RL4379 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 116253195 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL3453 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251683 Common - hypothetical protein RL1919 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 116250707 Nonpathogen - putative transmembrane protein RL0933 7 None None None 116250764 Common matA putative malonyl-CoA decarboxylase RL0990 29 None None None 116249843 Common - putative dTDP-glucose 4-6-dehydratase-like protein (UDP-glucuronic acid decarboxylase) RL0077 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116252471 Common - putative short-chain dehydrogenase/reductase RL2725 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252609 Common - hypothetical protein RL2862 18 None None None 116250317 Common - putative ATP-binding component of ABC transporter RL0545 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 116254067 Common - putative transmembrane protein RL4332 31 COG1434 COG1434, Uncharacterized conserved protein Function unknown 116251443 Nonpathogen - hypothetical protein RL1677 4 None None None 116251088 Common - autolysin atle and putative transcriptional regulator atlr genes, complete cds (hypothetical protein se0751) RL1320 6 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116253574 Common - putative short-chain dehydrogenase/reductase RL3833 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251738 Common - hypothetical protein RL1974 111 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116250709 Common - putative kinase RL0935 178 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 116250993 Common - putative transmembrane protein RL1226 8 None None None 116253570 Common exoY putative exopolysaccharide production regulator RL3829 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 116252230 Common - hypothetical protein RL2483 17 COG3246 COG3246, Uncharacterized conserved protein Function unknown 116252442 Nonpathogen - hypothetical protein RL2695 1 None None None 116250335 Common - putative methyl-accepting chemotaxis protein RL0564 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116252275 Common - hypothetical protein RL2529 15 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 116250816 Common - putative solute-binding component of ABC transporter RL1043 73 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116253437 Common hmuS putative haem iron transport component RL3697 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 116251546 Common rpsC 30S ribosomal protein S3 RL1780 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 116249912 Common gyaR putative glyoxylate reductase RL0145 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 116250530 Common - putative methyl-accepting chemotaxis protein RL0758 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116253568 Common - hypothetical protein RL3827 10 None None None 116254226 Common - putative transmembrane protein RL4497 13 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 116252545 Common leuS putative leucyl-tRNA synthetase RL2798 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250390 Common - zinc-binding protein RL0618 30 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 116249858 Common - putative transmembrane component of ABC transporter RL0092 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250181 Common - hypothetical protein RL0412 26 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 116254242 Common argG argininosuccinate synthase RL4515 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 116252600 Common - hypothetical protein RL2853 24 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 116251776 Common - putative solute-binding component of ABC transporter RL2013 109 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116253754 Nonpathogen - hypothetical protein RL4015 7 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 116253656 Common algI putative poly(beta-D-mannuronate) O-acetylase RL3916 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 116250559 Common - hypothetical protein RL0787 17 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 116252148 Common - hypothetical protein RL2396 84 COG1801 COG1801, Uncharacterized conserved protein Function unknown 116250227 Common - putative transposase related protein RL0456B 68 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 116252004 Common - putative transmembrane transglycosylase associated protein RL2248 14 COG2261 COG2261, Predicted membrane protein Function unknown 116252130 Common - putative transmembrane component of ABC transporter RL2378 113 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116254361 Common - putative transmembrane component of transporter RL4635 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116253798 Common - putative transmembrane efflux transporter protein RL4059 106 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116249998 Common - hypothetical protein RL0231 3 None None None 116250249 Common nodG putative nodulation protein RL0478 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253478 Common - putative ATP-binding component of ABC transporter RL3737 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116252400 Common - putative transmembrane protein RL2654 153 COG5280 COG5280, Phage-related minor tail protein Function unknown 116250461 Common cheW putative CheW family chemotaxis protein RL0689 136 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 116250417 Common - putative short-chain dehydrogenase/reductase RL0645 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250527 Common glnA putative glutamine synthetase RL0755 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 116252119 Nonpathogen - hypothetical protein RL2367 1 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 116254215 Common - putative ATP-binding component of ABC transporter RL4486 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116250572 Common - putative transmembrane glycosyl transferase RL0801 119 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251628 Common - putative 4-hydroxyphenylpyruvate dioxygenase RL1863 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 116251329 Common gmk guanylate kinase RL1563 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 116249961 Common - putative AsnC transcriptional regulator RL0194 156 COG1522 Lrp, Transcriptional regulators Transcription 116252022 Common - hypothetical protein RL2266 89 COG1262 COG1262, Uncharacterized conserved protein Function unknown 116249778 Common gyrB DNA gyrase subunit B RL0012 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 116250005 Nonpathogen - hypothetical protein RL0238 1 None None None 116252520 Common - putative LysR family transcriptional regulator RL2774 140 COG0583 LysR, Transcriptional regulator Transcription 116250188 Common - putative transmembrane protein RL0419 16 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 116253227 Common petB putative cytochrome b RL3485 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 116251720 Common - putative transmembrane protein RL1956 10 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250437 Common - putative transmembrane exopolysaccharide production protein RL0665 21 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 116251781 Common - hypothetical protein RL2018 4 None None None 116250380 Nonpathogen - hypothetical protein RL0609 1 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 116252139 Common - hypothetical protein RL2387 41 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116250636 Common - putative LysR family transcriptional regulator RL0863 110 COG0583 LysR, Transcriptional regulator Transcription 116251302 Common - putative lysine decarboxylase family protein RL1536 121 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 116249791 Common - putative thioredoxin RL0025 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 116253684 Nonpathogen - putative transmembrane protein RL3944 1 None None None 116253098 Common - putative transmembrane component of ABC transporter RL3357 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116250742 Common - hypothetical protein RL0968 60 COG1733 COG1733, Predicted transcriptional regulators Transcription 116252984 Common - putative transmembrane transporter protein RL3242 74 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116253969 Common - putative GntR family transcriptional regulator RL4232 95 COG2186 FadR, Transcriptional regulators Transcription 116253877 Common - putative transmembrane transporter component RL4140 74 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 116250116 Common - putative LysR family transcriptional regulator RL0348 174 COG0583 LysR, Transcriptional regulator Transcription 161501790 Common rpsU 30S ribosomal protein S21 RL4130 40 None None None 116253056 Common mraW S-adenosyl-methyltransferase MraW RL3315 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 116250297 Nonpathogen - hypothetical protein RL0526 6 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 116250552 Common dppC putative didpeptide permease component of ABC transporter RL0780 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251200 Common feuQ putative two-component sensor histidine kinase transcriptional regulator RL1434 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251183 Common - putative IolH myo-inositol catabolism protein RL1417 27 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116253423 Common - putative transmembrane component of ABC transporter RL3682 155 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 116251852 Common aspB putative aspartate aminotransferase RL2092 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 116250142 Common - enoyl-CoA hydratase RL0373 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 116253791 Common - putative short-chain dehydrogenase/reductase RL4052 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116252568 Common cobD putative cobalamin biosynthesis protein RL2821 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 116252587 Common - putative ATP-binding component of ABC transporter RL2840 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116254358 Common - putative DeoR faimly transcriptional regulator RL4632 109 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 116253804 Common - hypothetical protein RL4066 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 116253832 Nonpathogen - hypothetical protein RL4095 2 None None None 116250268 Nonpathogen - putative transmembrane protein RL0497 1 None None None 116251255 Common - putative transmembrane MatE family transporter RL1489 142 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 116253016 Common - hypothetical protein RL3273 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 116250700 Common atpC F0F1 ATP synthase subunit C RL0926 42 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 116252770 Nonpathogen - hypothetical protein RL3025 1 None None None 116253158 Common - putative transmembrane protease protein RL3416 88 COG2321 COG2321, Predicted metalloprotease General function prediction only 116254083 Common - putative DNAJ chaperone family protein RL4350 173 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 116254182 Common - putative ATP-binding component of ABC transport RL4451 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 116252796 Common - putative cationic solute-binding component of ABC transporter RL3052 88 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 116251606 Nonpathogen - putative transmembrane protein RL1840 7 COG3941 COG3941, Mu-like prophage protein General function prediction only 116254018 Common hemK putative protein methyltransferase RL4281 224 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 116252944 Common - hypothetical protein RL3202 9 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 116253707 Common - hypothetical protein RL3967 101 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 116252154 Nonpathogen - hypothetical protein RL2402 1 None None None 116251964 Common - putative hydrolase RL2208 158 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116250588 Nonpathogen - hypothetical protein RL0816 4 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 116252372 Common - putative transmembrane protein RL2626 61 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 116254091 Common - putative TRAP family solute-binding component of C4-dicarboxylate transporter RL4358 117 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 116251281 Common recO DNA repair protein RecO RL1515 59 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 116250401 Common - putative component of ABC transporter RL0629 29 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252017 Common - hypothetical protein RL2261 12 COG3900 COG3900, Predicted periplasmic protein Function unknown 116250475 Common motA flagellar motor protein MotA RL0703 105 COG1291 MotA, Flagellar motor component Cell motility and secretion 116250430 Common - hypothetical protein RL0658 20 None None None 116254074 Common - hypothetical protein RL4339 69 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116254268 Common - hypothetical protein RL4541 11 None None None 116253766 Common - putative short-chain dehydrogenase/reductase RL4027 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252188 Common - putative efflux protein RL2435 35 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116252110 Common - putative short-chain dehydrogenase/reductase RL2358 212 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 116254126 Common fdsG formate dehydrogenase subunit gamma RL4393 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 116250919 Common - putative exported arylsulfatase RL1149 67 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116251172 Common - putative LysR family transcriptional regulator RL1404 89 COG0583 LysR, Transcriptional regulator Transcription 116251427 Common cpsA putative transmembrane sugar transferase protein RL1661 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 116250341 Common - hypothetical protein RL0570 8 None None None 116251962 Common - putative salicylate hydroxylase RL2206 86 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 116252687 Common - putative AraC family transcriptional regulator RL2940 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116253165 Common - putative lipopolysaccharide core biosynthesis protein RL3423 203 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116251955 Common - hypothetical protein RL2199 18 None None None 116254223 Common gcp O-sialoglycoprotein endopeptidase RL4494 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 116252929 Nonpathogen - hypothetical protein RL3187 1 None None None 116254327 Common - hypothetical protein RL4601 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 116253923 Common - putative oxidoreductase RL4186 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251120 Common - putative exported beta-lactamase RL1352 62 COG2367 PenP, Beta-lactamase class A Defense mechanisms 116253515 Common - putative transmembrane AcrB/D/F RND family transporter RL3774 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116254141 Common atpA F0F1 ATP synthase subunit alpha RL4409 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 116254451 Common acs acetyl-CoA synthetase RL4727 213 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 116251997 Common pdhA putative pyruvate dehydrogenase subunit RL2241 167 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 116250233 Common - putative transmembrane protein RL0462 3 None None None 116252915 Nonpathogen - hypothetical protein RL3173 1 None None None 116250240 Common - putative exported surface protein RL0469 5 None None None 116254299 Common - hypothetical protein RL4573 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 116250327 Common - 2'-deoxycytidine 5'-triphosphate deaminase RL0555 57 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 116253742 Common - hypothetical protein RL4003 30 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 116252379 Common gstA putative glutathione S-transferase RL2633 89 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251467 Common nqo6 NADH dehydrogenase subunit B RL1701 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 116250595 Common - putative hexapeptide repeat acetyltransferase RL0823 171 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 116251332 Common - hypothetical protein RL1566 35 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 116250653 Common hisG ATP phosphoribosyltransferase catalytic subunit RL0879 210 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 116250947 Nonpathogen - hypothetical protein RL1179 2 None None None 116250281 Common - putative ATP-binding component of ABC transporter RL0510 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 116249905 Common - putative glyoxalase/dioxygenase RL0138 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116250989 Common - hypothetical protein RL1222 36 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116251594 Common - putative N-terminal membrane-anchored dehydrogenase RL1828 78 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 116250283 Common - putative solute-binding component of ABC transporter RL0512 85 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 116253806 Common - putative peptidase RL4068 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 116250865 Common - putative beta-lactamase family protein RL1093 140 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116250553 Common dppD putative dipeptide ABC transporter component RL0781 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250968 Common - putative transcriptional regulator RL1201 73 COG3903 COG3903, Predicted ATPase General function prediction only 116253126 Common - hypothetical protein RL3384 2 None None None 116253967 Common araG L-arabinose transporter ATP-binding protein RL4230 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116252191 Nonpathogen - hypothetical protein RL2438 1 None None None 116252690 Common - putative LysR family transcriptional regulator RL2943 123 COG0583 LysR, Transcriptional regulator Transcription 116250939 Nonpathogen - hypothetical protein RL1171 2 None None None 116249800 Common - hypothetical protein RL0034 28 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 116251539 Common rpsJ 30S ribosomal protein S10 RL1773 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 116253663 Nonpathogen - hypothetical protein RL3923 1 None None None 116250870 Common hsdM2 putative type I restriction enzyme modification methylase subunit RL1098 14 None None None 116253476 Common ureA urease subunit gamma RL3735 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 116253658 Nonpathogen - hypothetical protein RL3918 1 None None None 116252460 Common - putative substrate-binding ferrisiderophore receptor RL2713 81 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 116252503 Nonpathogen - putative transmembrane protein RL2757 11 COG5530 COG5530, Predicted integral membrane protein Function unknown 116254003 Common - putative transcriptional regulatory protein RL4266 77 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 116253626 Common sitC putative Fur regulated salmonella iron ABC transporter component RL3886 192 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 116253507 Common rpoH RNA polymerase factor sigma-32 RL3766 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 116252392 Common - hypothetical protein RL2646 43 COG3768 COG3768, Predicted membrane protein Function unknown 116252215 Common - putative transmembrane protein RL2463B 58 COG3174 COG3174, Predicted membrane protein Function unknown 116253044 Common - putative transmembrane transporter protein RL3303 121 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 116249783 Common - putative PHB depolymerase RL0017 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 116250949 Common - hypothetical protein RL1181 52 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 116252374 Common - putative rRNA methylase family protein RL2628 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 116250912 Common - hypothetical protein RL1141 2 None None None 116254167 Common kgd alpha-ketoglutarate decarboxylase RL4435 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 116251495 Common - putative two-component response regulator transcriptional regulatory protein RL1729 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 116251375 Common parC DNA topoisomerase IV subunit A RL1609 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 116252895 Common ribH riboflavin synthase subunit beta RL3153 87 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 116249944 Common phnG putative phosphonate utilisation protein RL0177 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 116253719 Common - putative phosphatase RL3980 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 116250569 Common - hypothetical protein RL0798 14 None None None 116253678 Common - putative phage terminase large subunit RL3938 23 None None None 116251996 Common - putative cell division protein RL2240 29 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 116253321 Common lldD putative L-lactate dehydrogenase RL3578 121 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 116252081 Common - putative ATP-binding component of ABC transporter RL2328 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116253740 Common - hypothetical protein RL4001 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 116250546 Common - putative LysR family transcription regulator protein RL0774 163 COG0583 LysR, Transcriptional regulator Transcription 116251668 Nonpathogen - hypothetical protein RL1904 1 None None None 116251446 Common - hypothetical protein RL1680 32 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 116253933 Common - hypothetical protein RL4196 11 None None None 116252651 Common ptsI putative phosphoenolpyruvate-protein phosphotransferase RL2904 197 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 116250907 Common - putative transmembrane copper resistance protein RL1135 35 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 116252922 Nonpathogen - hypothetical protein RL3180 1 None None None 116249920 Common - putative penicillin-binding transpeptidase/transglycosylase protein RL0153 205 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 116250486 Common flgH flagellar basal body L-ring protein RL0714 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 116251365 Common ppk polyphosphate kinase RL1599 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 116253229 Common - putative transmembrane exo/endo phosphatase family protein RL3487 7 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 116250325 Common apaG ApaG RL0553 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 116249867 Common gabD Succinate-semialdehyde dehydrogenase [NADP+] (SSDH). RL0101 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116253788 Common - hypothetical protein RL4049 41 None None None 116253021 Nonpathogen - hypothetical protein RL3278 1 None None None 116250216 Common - hypothetical protein RL0447 65 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 116251677 Common - putative transmembrane protein RL1913 57 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 116253107 Common - putative flavoprotein RL3366 92 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 116251745 Common cfa putative cyclopropane-fatty-acyl-phospholipid synthase RL1982 138 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 116254263 Common acnA aconitate hydratase RL4536 223 COG1048 AcnA, Aconitase A Energy production and conversion 116251125 Common - putative homocysteine S-methyltransferase RL1357 45 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 116252707 Common - putative acetyltransferase RL2960 8 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 116251213 Common - putative methyl-accepting chemotaxis-related protein RL1447 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116253384 Common - putative glycosyl hydrolase RL3642 33 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 116251465 Nonpathogen - hypothetical protein RL1699 1 None None None 116252920 Common znuA putative high-affinity zinc uptake system protein RL3178 149 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 116250343 Common - dihydroorotate dehydrogenase 2 RL0572 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 116251819 Common gidA tRNA (uracil-5-)-methyltransferase Gid RL2059 174 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 116250889 Nonpathogen - hypothetical protein RL1117 1 None None None 116252875 Common ugpE putative SN-glycerol-3-phosphate transport system transmembrane component of ABC transporter RL3133 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116252666 Common - putative transmembrane component of ABC transporter RL2919 168 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116252338 Common - hypothetical protein RL2592 48 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 116251230 Common - putative transmembrane MFS permease RL1464 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116251828 Common radC DNA repair protein RadC RL2068 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 116252334 Common tyrS tyrosyl-tRNA synthetase RL2588 217 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116250771 Common - putative methionyl-tRNA synthetase RL0998 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116252862 Common - putative two component regulator sensor histidine kinase transcriptional regulatory protein RL3120 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253373 Common - putative glycosyltransferase RL3630 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116250661 Common - putative plasmid stability-like protein RL0887 55 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 116252052 Common aldH putative aldehyde dehydrogenase RL2296 193 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116250958 Common - putative HTH-type transcriptional regulator RL1190 30 COG0640 ArsR, Predicted transcriptional regulators Transcription 116252557 Common - putative glyoxalase RL2810 30 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 116253671 Common - hypothetical protein RL3931 6 None None None 116250422 Common - sorbitol dehydrogenase RL0650 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116254209 Common - putative GntR family transcriptional regulator RL4480 114 COG1802 GntR, Transcriptional regulators Transcription 116253220 Common - hypothetical protein RL3478 7 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 116251209 Common glnE putative glutamate-ammonia-ligase adenylyltransferase RL1443 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 116249983 Common cpaE putative pilus assembly protein RL0216 79 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 116251162 Common - hypothetical protein RL1394 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 116252318 Common gcvT putative aminomethyltransferase (glycine cleavage system t protein) RL2572 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 116252909 Common - putative acetyltransferase RL3167 89 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116253724 Common mcpA putative chemoreceptor McpA (methyl-accepting chemotaxis protein) RL3985 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116250333 Common - hypothetical protein RL0562 3 None None None 116250277 Common - hypothetical protein RL0506 35 None None None 116252232 Common - putative LysR family transcriptional regulator RL2486 93 COG0583 LysR, Transcriptional regulator Transcription 116249836 Common - hypothetical protein RL0070 6 None None None 116252766 Common - putative transmembrane protein RL3021 15 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 116252963 Common - hypothetical protein RL3221 78 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116253065 Common - putative SLT domain transglycosylase RL3324 28 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 116252467 Common rbsC putative ribose transport system permease protein RL2720 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116252050 Common - putative beta-lactamase/hydrolase RL2294 77 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116253908 Common - putative endonuclease RL4171 55 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116250778 Common - hypothetical protein RL1005 61 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 116252538 Common - hypothetical protein RL2791 34 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116253493 Common pssA putative transferase involved in exopolysaccharide biosynthesis RL3752 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 116251619 Common - putative endoribonuclease L-PSP family protein RL1853 92 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116251724 Common - putative LysR family transcriptional regulator RL1960 183 COG0583 LysR, Transcriptional regulator Transcription 116251100 Common nadE NAD synthetase RL1332 206 COG0171 NadE, NAD synthase Coenzyme metabolism 116251396 Common - hypothetical protein RL1630 30 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116254374 Common - putative transmembrane component of ABC transporter RL4649 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250676 Common - 3-deoxy-D-manno-octulosonic-acid transferase RL0902 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 116254196 Common - putative transmembrane component of ABC transporter RL4465 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116252160 Nonpathogen - hypothetical protein RL2408 11 None None None 116251626 Common - putative AsnC family transcriptional regulator RL1861 149 COG1522 Lrp, Transcriptional regulators Transcription 116254244 Common - putative LysE family transmembrane efflux family protein RL4517 115 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116249988 Common - hypothetical protein atu0215 (agr_c_369p) RL0221 33 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 116252423 Nonpathogen - hypothetical protein RL2676 1 None None None 116251845 Common - NADH dehydrogenase RL2085 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 116252401 Nonpathogen - hypothetical protein RL2655 1 None None None 116253244 Common - putative transmembrane protein RL3502 34 COG5426 COG5426, Uncharacterized membrane protein Function unknown 116254287 Common - putative cNMP-binding protein RL4560 92 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116251730 Common ald putative alanine dehydrogenase RL1966 163 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 116250970 Common - putative metallo-beta-lactamase family methyl parathion hydrolase RL1203 86 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116253214 Common - putative GGDEF/EAL transmembrane sensory box protein RL3472 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116253837 Common - putative transmembrane protein RL4100 40 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 116251513 Common - putative solute-binding component of ABC transporter RL1747 100 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253337 Common dapA putative dihydrodipicolinate synthase RL3594 196 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116253487 Common - putative transmembrane protein RL3746 10 None None None 116253589 Common - putative short-chain dehydrogenase/reductase RL3848 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250403 Common - ptative transmembrane component of ABC transporter RL0631 116 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116251015 Common - hypothetical protein RL1248 7 None None None 116250564 Common - putative transposase-related protein RL0793 61 None None None 116254383 Common exoB putative UDP-glucose 4-epimerase RL4658 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 116250155 Common - hypothetical protein RL0386 20 COG5552 COG5552, Uncharacterized conserved protein Function unknown 116250083 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein RL0315 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 116252718 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2972 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253915 Common - putative LacI family transcriptional regulator RL4178 113 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253455 Common - putative TetR family transcriptional regulator RL3715 112 COG1309 AcrR, Transcriptional regulator Transcription 116251400 Common hppA membrane-bound proton-translocating pyrophosphatase RL1634 100 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 116251973 Common - putative glycerophosphoryl diester phosphodiesterase RL2217 127 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 116252343 Common - putative solute-binding component of ABC transporter RL2597 51 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 116253970 Common - putative epimerase RL4233 125 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116253616 Common nodT putative exported nodulation protein RL3876 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116250459 Common cheY putative CheY response regulator transcriptional regulatory protein RL0687 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116252049 Common - putative transmembrane transporter RL2293 73 COG0679 COG0679, Predicted permeases General function prediction only 116251311 Common - putative short-chain dehydrogenase/reductase RL1545 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253495 Common - hypothetical protein RL3754 27 None None None 116252611 Nonpathogen - hypothetical protein RL2864 1 None None None 116250306 Nonpathogen fixQ putative cbb3 cytochrome oxidase subunit FixQ protein RL0533A 5 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 116253954 Common mtlF putative mannitol transmembrane permease component of ABC transporter RL4217 161 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250493 Common flaC putative flagellin C RL0721 81 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116250441 Common - putative stress-induced protein RL0669 7 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116252849 Common - putative ATP-binding component of ABC transporter RL3108 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116250174 Common glnD PII uridylyl-transferase RL0405 126 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 116254044 Nonpathogen - hypothetical protein RL4308 2 None None None 116252096 Common - putative LacI family transcriptional regulator RL2343 126 COG1609 PurR, Transcriptional regulators Transcription 116250697 Common - putative hydrolase RL0923 47 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 116250781 Common - putative GGDEF/EAL transmembrane sensory box protein RL1008 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116251153 Common - putative short-chain dehydrogenase/oxidoreductase RL1385 202 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253028 Common prmA ribosomal protein L11 methyltransferase RL3287 169 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 116250448 Common - putative two-component response regulator transcriptional regulatory protein RL0676 99 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116250097 Common - putative NADH-ubiquinone oxidoreductase subunit RL0329 134 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116251947 Nonpathogen - hypothetical protein RL2190 1 None None None 116252702 Nonpathogen - hypothetical protein RL2955 4 None None None 116252999 Common thyA thymidylate synthase RL3256 143 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 116252269 Common - putative DNA-damage-inducible protein RL2523 31 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 116251035 Common - hypothetical protein RL1268 9 None None None 116253983 Common - putative GFO/IDH/MocA family oxidoreductase RL4246 159 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116253043 Common aqpZ aquaporin Z RL3302 104 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 116251769 Common - putative transglycosylase RL2006 116 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 116251643 Common - putative peptidoglycan binding protein RL1878 21 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 116252069 Common - putative cyclase/kinase RL2316 28 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116252478 Common - putative protein kinase RL2732 116 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 116253548 Common - putative solute-binding component of ABC transporter protein RL3807 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253355 Common ilvD dihydroxy-acid dehydratase RL3612 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 116253888 Common - putative transposon-related protein RL4151 22 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 116253480 Common - putative transmembrane component of ABC transporter RL3739 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 116252576 Common cobO cob(I)yrinic acid a,c-diamide adenosyltransferase RL2829 137 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 116252900 Common - putative HTH-type transcriptional regulator RL3158 176 COG0583 LysR, Transcriptional regulator Transcription 116253413 Common - hypothetical protein RL3672 37 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 116252997 Common hflK putative transmembrane serine protease RL3254 165 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 116250624 Common - putative LysR family transcriptional regulator RL0851 190 COG0583 LysR, Transcriptional regulator Transcription 116250254 Common - putative short-chain dehydrogenase/oxidoreductase RL0482A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250683 Common - hypothetical protein RL0909 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 116252620 Common cya3 putative transmembrane adenylate cyclase RL2873 29 COG5616 COG5616, Predicted integral membrane protein Function unknown 116253296 Common - putative transmembrane protein RL3554 39 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 116252977 Common - putative RNA polymerase ECF sigma factor RL3235 122 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116251077 Nonpathogen - putative transmembrane protein RL1309 4 None None None 116253855 Common pgm phosphoglucomutase RL4118 188 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 116252261 Common gyrB DNA topoisomerase IV subunit B RL2515 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 116253947 Common cysZ CysZ-like protein RL4210 23 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 116254230 Common - putative transmembrane MFS family permease transporter RL4501 157 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 116250738 Common - putative cationic transport protein RL0964 50 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 116254427 Common - hypothetical protein RL4703 3 None None None 116253756 Common rpmE 50S ribosomal protein L31 RL4017 158 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 116250687 Common - putative PRC family protein RL0913 14 COG1873 COG1873, Uncharacterized conserved protein Function unknown 116250619 Common - hypothetical protein RL0846 68 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 116253444 Common - hypothetical protein RL3704 5 None None None 116251568 Common - putative sulfite oxidase subunit YedY RL1802 123 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 116251072 Common - hypothetical protein RL1304 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 116253977 Common - hypothetical protein RL4240 84 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 116251112 Common - hypothetical protein RL1344 96 COG2378 COG2378, Predicted transcriptional regulator Transcription 116249992 Common - amidase RL0225 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 116252677 Common - hypothetical protein RL2930 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 116254347 Common phaA acetyl-CoA acetyltransferase RL4621 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 116252482 Common maiA putative maleylacetoacetate isomerase RL2736 81 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116252990 Common - putative transmembrane efflux protein RL3247A 38 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116251906 Nonpathogen - hypothetical protein RL2148 2 None None None 116251940 Common - hypothetical protein RL2183 24 None None None 116254023 Common - hypothetical protein RL4287 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 116253848 Common - putative transglutaminase domain protein RL4111 84 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 116253762 Common - hypothetical protein RL4023 150 COG1360 MotB, Flagellar motor protein Cell motility and secretion 116251225 Common - putative transmembrane protein RL1459 23 COG2962 RarD, Predicted permeases General function prediction only 116251673 Common - putative nonspecific acid phosphataser RL1909 26 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 116251657 Common - putative cation transporting P-type ATPase RL1892 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 116250853 Nonpathogen - hypothetical protein RL1080 1 None None None 116251267 Common - putative soluble lytic murein transglycosylase precursor RL1501 142 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 116252765 Common - putative RNA polymerase sigma factor RL3020 71 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116253783 Common purE putative phosphoribosylaminoimidazole carboxylase catalytic subunit RL4044 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 116249931 Common phnM putative phosphonate metabolism protein RL0164 53 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 116249885 Common - putative ribosomal RNA small subunit methyltransferase RL0119 81 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 116251097 Common - putative HlyD family efflux pump protein RL1329 141 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116251184 Common - putative LacI family transcriptional regulator RL1418 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250934 Common - putative ribonuclease-L-PSP family protein RL1166 106 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 116250025 Common - putative acetyltransferase RL0257 48 COG0456 RimI, Acetyltransferases General function prediction only 116251144 Common mrpE putative monovalent cation/H+ antiporter subunit E RL1376 80 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 116251350 Common moaE putative molybdopterin converting factor subunit RL1584 151 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 116253237 Common - hypothetical protein RL3495 2 None None None 116252661 Nonpathogen - hypothetical protein RL2914 1 None None None 116252128 Common - putative periplasmic-binding protein component of ABC transporter RL2376 113 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250797 Nonpathogen coxF putative cox locus protein RL1024 2 None None None 116253699 Common - hypothetical protein RL3959 9 None None None 116251591 Common - putative transmembrane component of ABC transporter RL1825 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116254002 Common msrB putative peptide methionine sulfoxide reductase RL4265 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 116252854 Nonpathogen - hypothetical protein RL3112A 1 None None None 116251245 Common - hypothetical protein RL1479 14 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 116251470 Common nqo2 NADH dehydrogenase subunit E RL1704 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 116251148 Common - hypothetical protein RL1380 96 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 116253071 Common - putative transmembrane component of ABC transporter RL3330 79 COG2510 COG2510, Predicted membrane protein Function unknown 116253686 Common - hypothetical protein RL3946 8 None None None 116250299 Nonpathogen - hypothetical protein RL0528 1 None None None 116250019 Common - putative glutamine amidotransferase RL0251 130 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 116250157 Common trmB tRNA (guanine-N(7))-methyltransferase RL0388 173 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 116250507 Common flhA flagellar biosynthesis protein A RL0735 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 116252971 Common - putative transmembrane transporter RL3229 201 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116251483 Common - putative lactoylglutathione lyase RL1717 89 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116251278 Common era GTP-binding protein Era RL1512 233 COG1159 Era, GTPase General function prediction only 116251984 Common - putative outer membrane protein RL2228 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 116254088 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha RL4355 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 116254117 Common arcA putative arginase RL4384 108 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 116250088 Common - hypothetical protein RL0320 25 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 116254396 Common rci putative shufflon-specific DNA recombinase RL4671 167 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 116253222 Nonpathogen - putative transmembrane protein RL3480 11 None None None 116250511 Common - hypothetical protein RL0739 10 None None None 116253007 Common - putative transmembrane protein RL3264 48 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 116251840 Common - putative acetyltransferase RL2080 9 COG0456 RimI, Acetyltransferases General function prediction only 116251477 Common nuoK NADH dehydrogenase subunit K RL1711 135 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 116250396 Common - hypothetical protein RL0624 2 None None None 116252817 Nonpathogen - hypothetical protein RL3073 1 None None None 116250589 Nonpathogen - putative transmembrane protein RL0817 1 None None None 116250364 Common - hypothetical protein RL0593 37 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 116251585 Common - putative two component sensor histidine kinase transcriptional regulatory protein RL1819 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116251972 Common - hypothetical protein RL2216 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 116251253 Common - hypothetical protein RL1487 2 None None None 116252957 Common - putative AsnC family transcriptional regulator RL3215 123 COG1522 Lrp, Transcriptional regulators Transcription 116253733 Common atvA putative acid tolerance protein RL3994 19 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 116249848 Common - putative solute-binding component of ABC transporter RL0082 46 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251344 Common dinB putative damage inducible protein RL1578 36 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 116251935 Common - putative cell division protein RL2178 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 116250119 Common - putative AsnC family transcriptional regulator RL0350A 149 COG1522 Lrp, Transcriptional regulators Transcription 116252432 Nonpathogen - hypothetical protein RL2685 1 None None None 116252014 Nonpathogen - hypothetical protein RL2258 1 None None None 116253078 Common - putative L-carnitine dehydrogenase-like protein RL3337 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 116251714 Common - putative molybdenum cofactor biosynthesis protein RL1950 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 116253894 Common - putative LysR family transcriptional regulator RL4157 173 COG0583 LysR, Transcriptional regulator Transcription 116252203 Nonpathogen - hypothetical protein RL2452 3 None None None 116251304 Common leuA putative alpha-isopropylmalate/homocitrate synthase family transferase RL1538 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 116253875 Common - hypothetical protein RL4138 7 None None None 116254076 Common - hypothetical protein RL4341 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 116253133 Nonpathogen - hypothetical protein RL3391 3 None None None 116251284 Common - putative HD domain protein RL1518 57 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 116251708 Common - hypothetical protein RL1944 14 None None None 116251850 Common - 3-dehydroquinate dehydratase RL2090 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 116253871 Common pntB putative transmembrane NAD(P) transhydrogenase subunit beta RL4134 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 116252897 Common - putative cytochrome b561 RL3155 77 COG3038 CybB, Cytochrome B561 Energy production and conversion 116253356 Common - putative aldehyde dehydrogenase RL3613 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116254188 Common - putative transmembrane component of ABC transporter RL4457 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116250027 Common - putative acetylpolyamine aminohydrolase RL0259 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 116250525 Common zwf glucose-6-phosphate 1-dehydrogenase RL0753 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 116251275 Common acpS 4'-phosphopantetheinyl transferase RL1509 159 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 116253179 Common - hypothetical protein RL3437 7 None None None 116252311 Common - putative chaperone protein RL2565 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 116252485 Common - putative two-component response regulator transcriptional regulatory protein RL2739 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116251998 Common pdhB pyruvate dehydrogenase subunit beta RL2242 214 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 116251252 Common - putative LysR family transcriptional activator RL1486 60 COG0583 LysR, Transcriptional regulator Transcription 116251434 Common argC N-acetyl-gamma-glutamyl-phosphate reductase RL1668 204 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 116254037 Common acsA putative acetyl-coenzyme A synthetase RL4301 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 116254155 Common dapA putative dihydrodipicolinate synthase RL4423 193 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 116252845 Common - putative oxidoreductase RL3104 131 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116249899 Common - hypothetical protein RL0132 85 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 116252689 Common - hypothetical protein RL2942 120 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116249861 Common - putative ATP-binding component of ABC transporter protein RL0095 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116251578 Common - putative hydrolase RL1812 100 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116254011 Common - putative HlyD family transmembrane efflux protein RL4274 151 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116253805 Common - putative two-component response regulator with sigma 54 interacting domain transcriptional regulatory protein RL4067 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116254024 Common - putative amidohydrolase RL4288 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 116253309 Common - hypothetical protein RL3567 5 None None None 116254081 Common cobT putative aerobic cobaltochelatase RL4348 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 116252254 Common gltA putative citrate synthase II RL2508 181 COG0372 GltA, Citrate synthase Energy production and conversion 116252402 Common - putative D-alanyl-D-alanine carboxypeptidase RL2656 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116249909 Common - putative transmembrane permease protein RL0142 150 COG0679 COG0679, Predicted permeases General function prediction only 116250395 Common - putative transmembrane component of ABC transporter RL0623 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 116251855 Common - hypothetical protein RL2095 3 None None None 116251029 Common - putative phosphoadenosine phosphosulfate reductase RL1262 152 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 116250152 Common iunH putative inosine-uridine preferring nucleoside hydrolase RL0383 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 116252527 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase RL2781 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 116254368 Common - putative transmembrane protein RL4643 37 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 116253851 Common glgP putative glycogen phosphorylase RL4114 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 116254097 Common - putative amidohydrolase RL4364 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 116249900 Common - hypothetical protein RL0133 166 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 116251632 Common - hypothetical protein RL1867 12 COG3904 COG3904, Predicted periplasmic protein Function unknown 116251588 Common - putative enoyl-CoA hydratase RL1822 160 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 116252874 Common ugpC putative SN-glycerol-3-phosphate transport ATP-binding protein component of ABC transporter RL3132 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116251717 Common ilvA threonine dehydratase RL1953 211 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 116252939 Common - putative short-chain dehydrogenase/oxidoreductase RL3197 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116250896 Common - hypothetical protein RL1124 10 None None None 116254317 Common - putative transmembrane teichuronic acid biosynthesis protein RL4591 20 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116250669 Nonpathogen - hypothetical protein RL0895 4 None None None 116252440 Common - hypothetical protein RL2693 9 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 116252623 Nonpathogen - putative transmembrane protein RL2876 2 None None None 116252923 Common - hypothetical protein RL3181 8 COG5455 COG5455, Predicted integral membrane protein Function unknown 116250221 Common engB GTPase EngB RL0452 176 COG0218 COG0218, Predicted GTPase General function prediction only 116253217 Common - putative acetyltransferase RL3475 23 COG3393 COG3393, Predicted acetyltransferase General function prediction only 116250774 Common - hypothetical protein RL1001 11 None None None 116253292 Common - putative glycosylltransferase RL3550 158 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116252448 Common fumC fumarate hydratase RL2701 213 COG0114 FumC, Fumarase Energy production and conversion 116251604 Common ubiE putative ubiquinone/menaquinone biosynthesis methyltransferase RL1838 170 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116249938 Common - putative acetyltransferase RL0171 69 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116251238 Nonpathogen - putative transmembrane protein RL1472 4 None None None 116253313 Common xdhB putative xanthine dehydrogenase RL3571 107 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 116250222 Common oxaA putative inner membrane protein translocase component YidC RL0453 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 116253636 Common - putative transmembrane protein RL3896 13 None None None 116250941 Nonpathogen - putative transmembrane protein RL1173 7 None None None 116252674 Common ohrB putative organic hydroperoxide resistance protein RL2927 84 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116250651 Common hisS histidyl-tRNA synthetase RL0877 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116254306 Common - putative ATP-binding component of ABC transporter RL4580 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 116253163 Common - hypothetical protein RL3421 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 116250467 Common fliF flagellar MS-ring protein RL0695 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 116250276 Common fadD acyl-CoA synthetase RL0505 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116252913 Common - putative transmembrane protein RL3171 18 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 116253205 Common lgt prolipoprotein diacylglyceryl transferase RL3463 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 116252638 Common - putative cationic efflux system protein RL2891 213 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116251777 Common - putative adenine deaminase RL2014 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 116250705 Common - hypothetical protein RL0931 107 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 116251794 Common - hypothetical protein RL2034 8 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 116251575 Nonpathogen - hypothetical protein RL1809 1 None None None 116252793 Common - hypothetical protein RL3049 4 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 116253385 Common - putative glycosyl transferase RL3643 203 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116250991 Common cya1 putative adenylate/guanylate cyclase RL1224 92 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116253702 Common - putative heat resistant agglutinin 1 RL3962 22 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 116251914 Common - hypothetical protein RL2156 26 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 116253795 Common - putative decarboxylase RL4056 31 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 116250867 Nonpathogen - hypothetical protein RL1095 1 None None None 116251736 Common - hypothetical protein RL1972 10 None None None 116252099 Common - putative transmembrane component of ABC transporter RL2346 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250845 Common - putative transcriptional regulator RL1072 33 COG0640 ArsR, Predicted transcriptional regulators Transcription 116251778 Common - hypothetical protein RL2015 3 None None None 116251389 Common rfbA putative glucose-1-phosphate thymidylyltransferase RL1623 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 116250110 Common - putative ferritin-family protein RL0342 131 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 116253972 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase RL4235 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116253750 Common pgk phosphoglycerate kinase RL4011 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 116250065 Nonpathogen - hypothetical protein RL0297 9 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 116251358 Common - putative molybdopterin-containing oxidoreductase RL1592 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 116252493 Common rbsK putative ribokinase RL2747 194 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116252580 Common - putative transmembrane ion channel protein RL2833 157 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 116253226 Common petC putative cytochrome c1 precursor RL3484 60 COG2857 CYT1, Cytochrome c1 Energy production and conversion 116249945 Common - putative GntR family transcriptional regulator RL0178 109 COG2188 PhnF, Transcriptional regulators Transcription 116251514 Common - short chain dehydrogenase RL1748 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251760 Common - putative ATP-binding component of ABC transporter RL1997 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116250165 Common - putative acyltransferase RL0396 99 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 116250245 Common - putative aldo-keto reductase RL0474 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116253696 Common - putative site-specific DNA recombinase RL3956 82 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 116250319 Common phoB putative phosphate regulon two-component regulator transcriptional regulatory protein RL0547 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116253654 Nonpathogen - hypothetical protein RL3914 1 None None None 116250195 Common - putative methyl-accepting chemotaxis protein RL0426 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116254143 Common - putative transmembrane protein RL4411 6 None None None 116250554 Common dppF dipeptide transporter ATP-binding subunit RL0782 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 116252642 Common - putative solute-binding component of ABC transporter RL2895 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253769 Common cheW putative chemotaxis protein RL4030 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 116251793 Common - putative protein-l-isoaspartate o-methyltransferase RL2033 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 116252981 Common nha1 putative high-molecular weight cobalt-containing nitrile hydratase subunit alpha RL3239 21 None None None 116254264 Common ccmA putative cytochrome c biogenesis ATP-binding export protein RL4537 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 116254229 Common - glutamine amidotransferase RL4500 112 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 116252355 Common - hypothetical protein RL2609 6 None None None 116252941 Common - putative aminotransferase RL3199 224 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 116251171 Common - putative transmembrane efflux protein RL1403 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116249814 Common hisB imidazoleglycerol-phosphate dehydratase RL0048 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 116250411 Common - hypothetical protein RL0639 47 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251939 Nonpathogen - hypothetical protein RL2182 10 None None None 116250818 Common - putative transmembrane component of ABC transporter RL1045 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116250311 Common - hypothetical protein RL0539 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 116251323 Common fabD putative malonyl CoA-acyl carrier protein transacylase RL1557 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 116253101 Common - hypothetical protein RL3360 62 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 116250037 Common pheS phenylalanyl-tRNA synthetase subunit alpha RL0269 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 116253053 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase RL3312 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 116250282 Common - putative transmembrane component of ABC transporter RL0511 139 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 116253143 Common - hypothetical protein RL3401 18 COG4274 COG4274, Uncharacterized conserved protein Function unknown 116252156 Common - putative peptidyl-prolyl cis-trans isomerase (cyclophilin) RL2404 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 116251195 Common - hypothetical protein RL1429 10 COG3179 COG3179, Predicted chitinase General function prediction only 116254461 Common gidB glucose-inhibited division protein B RL4737 140 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 116250660 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase RL0886 211 COG0196 RibF, FAD synthase Coenzyme metabolism 116252167 Nonpathogen - hypothetical protein RL2415 1 None None None 116251805 Common scpB putative chromosome segregation and condensation protein B RL2045 133 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 116250435 Nonpathogen - hypothetical protein RL0663 1 None None None 116251308 Common - hypothetical protein RL1542 62 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116252028 Nonpathogen - hypothetical protein RL2272 4 None None None 116249890 Common rbfA ribosome-binding factor A RL0124 95 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 116252071 Nonpathogen - hypothetical protein RL2318 1 None None None 116252650 Common - putative multiphosphoryl transfer/phosphocarrier protein RL2903 87 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 116251661 Nonpathogen - hypothetical protein RL1896 1 None None None 116252133 Common - putative bifunctional GlmU protein RL2381 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 116252272 Common - putative oxidoreductase RL2526 78 COG0778 NfnB, Nitroreductase Energy production and conversion 116249879 Nonpathogen - hypothetical protein RL0113 1 None None None 116252162 Common - putative transcriptional regulatory protein RL2410 141 COG1733 COG1733, Predicted transcriptional regulators Transcription 116249872 Common rpsA 30S ribosomal protein S1 RL0106 219 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 116253979 Common - putative ATP-binding component of ABC transporter RL4242 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116252114 Nonpathogen - hypothetical protein RL2362 1 None None None 116253955 Common mtlE putative mannitol-binding component of ABC transporter RL4218 111 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116251549 Common rpsQ 30S ribosomal protein S17 RL1783 220 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 116254389 Nonpathogen - putative transmembrane protein RL4664 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116253173 Common - putative MFS family transmembrane transporter RL3431 166 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253468 Common ureF putative urease accessory protein RL3727A 77 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 116249923 Nonpathogen - hypothetical protein RL0156 1 None None None 116250357 Common - putative transmembrane protein RL0586 28 None None None 116250338 Common - hypothetical protein RL0567 14 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 116251207 Common - putative two-component response regulator transcriptional regulatory protein RL1441 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116249981 Common rcpA putative pilus assembly protein RL0214 131 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 116254406 Common proB gamma-glutamyl kinase RL4682 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 116252566 Nonpathogen - hypothetical protein RL2819 1 None None None 116251431 Common - hypothetical protein RL1665 12 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 116254369 Common ndvB putative transmembrane beta (1-->2) glucan biosynthesis protein RL4644 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 116252784 Common - putative substrate-binding periplasmic protein RL3040 52 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 116253252 Common - hypothetical protein RL3510 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 116250369 Common - hypothetical protein RL0598 11 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 116252418 Common maeB malic enzyme RL2671 210 COG0281 SfcA, Malic enzyme Energy production and conversion 116250524 Common pgl putative 6-phosphogluconolactonase RL0752 107 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 116249804 Common - hypothetical protein RL0038 108 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 116254296 Common - putative ATP-dependent protease RL4570 42 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 116252073 Common - putative MarR family transcriptional regulator RL2320 28 COG1846 MarR, Transcriptional regulators Transcription 116253907 Common - putative GFO/IDH/MocA family oxidoreductase RL4170 118 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116252589 Common - putative transmembrane component of ABC transporter RL2842 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 116251047 Common ansA putative L-asparaginase II RL1280 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 116251831 Nonpathogen - putative transmembrane protein RL2071 1 None None None 116253259 Common - 7-cyano-7-deazaguanine reductase RL3517 119 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 116250747 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase RL0973 221 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 116252378 Common - putative acetyltransferase RL2632 57 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116254120 Common mcpA putative methyl-accepting chemotaxis protein RL4387 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116254434 Common - putative transmembrane transporter component RL4710 27 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 116252108 Common - putative aldo/keto reductase protein RL2356 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116252237 Common - hypothetical protein RL2491 4 None None None 116252295 Common - putative transmembrane protein RL2549 27 COG3503 COG3503, Predicted membrane protein Function unknown 116251697 Common - conserved hypothetical protein, possible fusion RL1933 14 None None None 116251406 Common ihfA integration host factor subunit alpha RL1640 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 116251478 Common nqo14 NADH dehydrogenase subunit L RL1712 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 116253189 Common - hypothetical protein RL3447 14 None None None 116254258 Common - putative transmembrane protein RL4531 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 116251222 Common - putative short-chain dehydrogenase/oxidoreductase RL1456 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251727 Common - hypothetical protein RL1963 3 None None None 116254318 Common - putative glycosyl transferase RL4592 32 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 116253401 Common - hypothetical protein RL3659 16 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 116254297 Common - putative thioredoxin RL4571 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 116251161 Common pbpF putative peptidoglycan biosynthesis/penicillin binding protein RL1393 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 116252932 Common - hypothetical protein RL3190 12 None None None 116252385 Common - putative indigoidine A related protein RL2639 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 116253927 Common - putative solute-binding component of ABC transporter RL4190 99 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116252181 Common cya putative adenylate cyclase RL2429 57 COG5616 COG5616, Predicted integral membrane protein Function unknown 116253184 Nonpathogen - hypothetical protein RL3442 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 116253839 Common - putative transmembrane protein RL4102 18 None None None 116251132 Common - putative transmembrane protein RL1364 177 COG0628 PerM, Predicted permease General function prediction only 116253261 Common - hypothetical protein RL3519 14 COG5482 COG5482, Uncharacterized conserved protein Function unknown 116252048 Common ubiF 2-octaprenyl-6-methoxyphenyl hydroxylase RL2292 129 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 116252341 Common - putative MutT/Nudix family protein RL2595 27 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116251318 Common rplI 50S ribosomal protein L9 RL1552 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 116254062 Common - putative two-component response regulator transcriptional regulatory protein RL4327 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116250120 Common - hypothetical protein RL0351 66 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116251782 Common - putative ATP-binding component of cationic ABC transporter RL2019 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 116252550 Common - hypothetical protein RL2803 19 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 116253034 Common ligA NAD-dependent DNA ligase LigA RL3293 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 116250975 Common - putative chaperone protein RL1208 98 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 116254453 Common flaC putative flagellin protein RL4729 102 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 116252007 Common flaR2 putative DNA topology modulation FlaR protein RL2251 39 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 116252226 Nonpathogen - hypothetical protein RL2479 1 None None None 116253070 Common - putative lytic transglycosylase RL3329 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 116252880 Common - hypothetical protein RL3139 11 None None None 116254305 Common - putative pilin protein RL4579 39 COG3342 COG3342, Uncharacterized conserved protein Function unknown 116252425 Nonpathogen - hypothetical protein RL2678 2 None None None 116254280 Common - putative solute-binding component of ABC transporter RL4553 164 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116249991 Common - putative dipeptidyl-peptidase RL0224 109 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 116252127 Common bmpA putative basic membrane lipoprotein RL2375 99 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 116253305 Common - putative RNA polymerase ECF sigma factor RL3563 44 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 116253634 Common - putative molydopterin-containing oxidoreductase RL3894 112 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 116250516 Common aglR putative HTH LacI family transcriptional regulator RL0744 127 COG1609 PurR, Transcriptional regulators Transcription 116254301 Common - putative solute-binding component of ABC transporter RL4575 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 116254042 Nonpathogen - hypothetical protein RL4306 1 None None None 116253549 Common - putative ROK family transcriptional regulator RL3808 152 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116253716 Common sqdC putative sulfolipid biosynthesis protein RL3977 195 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116252367 Common - putative inositol-1-monophosphatase RL2621 197 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116253993 Common exsD hypothetical protein RL4256 144 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 116251071 Common - putative MarR family transcriptional regulator RL1303 41 COG1846 MarR, Transcriptional regulators Transcription 116250749 Common - putative short-chain dehydrogenase RL0975 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251002 Nonpathogen - hypothetical protein RL1235 1 None None None 116252140 Common - putative Dsb family thioredoxin protein RL2388 85 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 116252244 Common - putative cytochrome c RL2498 52 COG3474 COG3474, Cytochrome c2 Energy production and conversion 116250906 Common - hypothetical protein RL1134 191 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 116254159 Common - hypothetical protein RL4427 47 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 116250013 Common - putative CDP-glucose 4,6-dehydratase RL0245 223 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116251689 Common - hypothetical protein RL1925 38 COG5361 COG5361, Uncharacterized conserved protein Function unknown 116250597 Common gmd putative GDP-mannose 4,6-dehydratase (GDP-d-mannose dehydratase) RL0825 224 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 116251502 Common smf putative smf protein RL1736 208 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 116253111 Common - putative solute-binding component of ABC transporter RL3370 23 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116252273 Common - hypothetical protein RL2527 13 None None None 116251412 Common bcsA putative cellulose synthase catalytic subunit [UDP-forming] RL1646 140 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251319 Common - putative transmembrane protein RL1553 10 None None None 116254290 Common - putative transmembrane DNA translocase RL4563 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 116252041 Common hflX putative GTP-binding protein RL2285 214 COG2262 HflX, GTPases General function prediction only 116253593 Nonpathogen - hypothetical protein RL3852 1 None None None 116254332 Common metA homoserine O-succinyltransferase RL4606 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 116254380 Common - putative rhizopine-binding ABC transporter protein RL4655 109 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253577 Common - putative transmembrane protein RL3836 55 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 116254248 Common - hypothetical protein RL4521 62 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 116252633 Common - putative transmembrane aquaporin RL2886 56 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 116252078 Common - putative solute-binding component of ABC transporter RL2325 58 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116253421 Common - hypothetical protein RL3680 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116253114 Nonpathogen - hypothetical protein RL3373 1 None None None 116252394 Common - putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase RL2648 198 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 116250830 Nonpathogen - hypothetical protein RL1057 1 None None None 116252179 Common - putative arginase family protein RL2427 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 116249914 Common - molybdopterin biosynthesis protein MoeB RL0147 221 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 116251701 Nonpathogen - hypothetical protein RL1937 1 None None None 116253597 Common - hypothetical protein RL3857 54 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 116253434 Common - hypothetical protein RL3693 11 None None None 116252773 Common - putative transmembrane protein RL3028 74 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116252559 Common - lipid A biosynthesis lauroyl acyltransferase RL2812 96 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 116250532 Common - hypothetical protein RL0760 6 None None None 116254129 Common - putative short-chain dehydrogenase/oxidoreductase/nodulation protein G RL4396 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250965 Common - hypothetical protein RL1198 18 COG1359 COG1359, Uncharacterized conserved protein Function unknown 116254228 Common - hypothetical protein RL4499 36 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 116252605 Nonpathogen - hypothetical protein RL2858 1 None None None 116252087 Common - putative AraC family transcriptional regulator RL2334 101 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116251291 Common - putative aminomethyltransferase RL1525 122 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 116253347 Nonpathogen - hypothetical protein RL3604 1 None None None 116251521 Common ppnK inorganic polyphosphate/ATP-NAD kinase RL1755 234 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 116252749 Common - putative acetyltransferase RL3004 55 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116250264 Common pyrC dihydroorotase RL0493 87 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 116250800 Nonpathogen - putative phosphotransferase RL1027 8 COG3896 COG3896, Chloramphenicol 3-O-phosphotransferase Defense mechanisms 116254137 Common pss putative exopolysaccharide production protein RL4404 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 116250985 Common - hypothetical protein RL1218 53 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116253709 Common tolB translocation protein TolB RL3969 152 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 116254324 Common - putative L-lysine 2,3-aminomutase RL4598 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 116253582 Common - putative UDP-glucose 4-epimerase RL3841 47 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116251136 Common pat putative phosphinothricin N-acetyltransferase RL1368 133 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116251891 Nonpathogen - hypothetical protein RL2131 1 None None None 116249972 Common upp uracil phosphoribosyltransferase RL0205 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 116253125 Common - hypothetical protein RL3383 3 None None None 116253013 Common - putative transport protein RL3270 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116250053 Common - putative transmembrane transporter protein RL0285 84 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 116254399 Nonpathogen - hypothetical protein RL4675 1 None None None 116251859 Common recJ putative single-stranded-DNA-specific exonuclease RL2099 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 116250740 Common - enoyl-CoA hydratase RL0966 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 116253749 Common cvrA potassium/proton antiporter RL4010 115 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 116251642 Common - putative protease RL1877 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116249819 Common - Cytochrome P450 4A3 precursor (CYPIVA3) (Lauric acid omega-hydroxylase) (P450-LA-omega 3). RL0053 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 116250753 Common - hypothetical protein RL0979 88 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 116250234 Nonpathogen - hypothetical protein RL0463 1 None None None 116251040 Common - putative transmembrane protein RL1273 35 COG3247 HdeD, Uncharacterized conserved protein Function unknown 116251756 Common - putative anionic substrate binding component of ABC transporter RL1993 76 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 116254217 Common - hypothetical protein RL4488 7 None None None 116252988 Common - hypothetical protein RL3246 84 COG0433 COG0433, Predicted ATPase General function prediction only 116253813 Common hemH ferrochelatase RL4076 151 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 116251862 Common cspA putative cold shock protein RL2102 156 COG1278 CspC, Cold shock proteins Transcription 116254102 Nonpathogen - hypothetical protein RL4369 1 None None None 116253773 Common cheW putative chemotaxis protein RL4034 123 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 116253796 Common - hypothetical protein RL4057 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116251381 Common - putative transmembrane protein RL1615 22 COG1714 COG1714, Predicted membrane protein/domain Function unknown 116254447 Common - hypothetical protein RL4723 45 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 116251948 Common - hypothetical protein RL2191 5 None None None 116250477 Common fliI flagellum-specific ATP synthase RL0705 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 116252206 Common - putative epoxide hydrolase RL2455 36 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116251458 Common - putative transmembrane protein RL1692 89 None None None 116250122 Common - putative transmembrane transport protein RL0353 75 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 116253924 Common - putative AraC family transcriptional regulator RL4187 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116251698 Nonpathogen - hypothetical protein RL1934 1 None None None 116251227 Common - putative magnesium transporter protein RL1461 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 116252529 Common - putative transmembrane protein RL2782 54 COG3577 COG3577, Predicted aspartyl protease General function prediction only 116250138 Common hutH putative histidine ammonia-lyase RL0369 109 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 116253282 Common - putative solute-binding component of ABC transporter RL3540 148 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 116250789 Common - putative D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein) RL1016 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 116251826 Common sthA soluble pyridine nucleotide transhydrogenase RL2066 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 116254432 Common - putative transmembrane lipid A 1-phosphatase RL4708 52 None None None 116251142 Common mrpC putative monovalent cation/H+ antiporter subunit C RL1374 91 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 116254118 Common rocD ornithine--oxo-acid transaminase RL4385 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 116249846 Common - hypothetical protein RL0080 6 None None None 116253006 Common - putative LysR family transcriptional regulator RL3263 168 COG0583 LysR, Transcriptional regulator Transcription 116253046 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase RL3305 150 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 116253567 Common - putative glycosyltransferase RL3826 15 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 116254236 Common dcp putative peptidyl-dipeptidase RL4507 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 116252131 Common - inner membrane ABC transporter permease protein YjfF RL2379 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116253781 Common - putative transcriptional regulator RL4042 67 COG0640 ArsR, Predicted transcriptional regulators Transcription 116251073 Common - hypothetical protein RL1305 9 None None None 116250713 Common - hypothetical protein RL0939 36 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 116251687 Nonpathogen - hypothetical protein RL1923 1 None None None 116252469 Common rbsA putative ribose transport ATP-binding component of ABC transporter protein RL2722 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116254350 Common rpmF 50S ribosomal protein L32 RL4624 117 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 116253731 Common - putative MutT/NUDIX family protein RL3992 33 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116251398 Common ribH riboflavin synthase subunit beta RL1632 213 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 116252245 Common iorA putative isoquinoline 1-oxidoreductase alpha subunit RL2499 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 116253513 Common ilvD dihydroxy-acid dehydratase RL3772 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 116254345 Nonpathogen - putative transmembrane protein RL4619 2 COG4803 COG4803, Predicted membrane protein Function unknown 116253868 Common - putative TPR repeat family protein RL4131 133 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 116251266 Common - putative hydrolase RL1500 80 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116251220 Common - putative HlyD family secretion protein RL1454 152 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116249906 Common - prephenate dehydratase RL0139 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 116250300 Common - putative transmembrane transporter RL0529 230 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116252595 Common - putative LysR family transcriptional regulator RL2848 166 COG0583 LysR, Transcriptional regulator Transcription 116252859 Common - putative transmembrane protein RL3117 42 None None None 116251250 Common - putative transmembrane protein RL1484 26 COG4852 COG4852, Predicted membrane protein Function unknown 116254206 Common - putative TRAP family transmembrane transporter protein RL4476 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 116251718 Common - hypothetical protein RL1954 14 COG5453 COG5453, Uncharacterized conserved protein Function unknown 116250725 Common glyS glycyl-tRNA synthetase subunit beta RL0951 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 116252852 Common - putative solute-binding component of ABC transporter RL3111 62 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250851 Common mutY putative A/G-specific adenine glycosylase RL1078 225 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 116253097 Common - putative GFO/IDH/MocA family oxidoreductase protein RL3356 152 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116250602 Nonpathogen - hypothetical protein RL0830 1 None None None 116252973 Common - putative MarR family transcriptional regulator RL3231 92 COG1846 MarR, Transcriptional regulators Transcription 116253738 Common - hypothetical protein RL3999 9 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116251864 Nonpathogen - hypothetical protein RL2103A 1 None None None 116253061 Common - putative signalling and peptidoglycan binding protein RL3320 111 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 116253073 Common - putative transcriptional regulator RL3332 185 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116253316 Common - hypothetical protein RL3573A 4 None None None 116249802 Common - putative two-component response regulator transcriptional regulatory protein RL0036 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116254100 Common eutP putative ethanolamine transmembrane permease transporter component RL4367 153 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 116252016 Nonpathogen - hypothetical protein RL2260 1 None None None 116251282 Common - putative general stress protein RL1516 170 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116252011 Common dus putative tRNA-dihydrouridine synthase (nitrogen regulation protein) RL2255 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 116253121 Common - putative two-component response regulator transcriptional regulatory protein RL3379 124 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 116253698 Common - putative sensory box GGDEF/EAL domain protein RL3958 193 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116250081 Common - putative aldehyde dehydrogenase RL0313 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116251901 Common - hypothetical protein RL2142 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 116253864 Common - hypothetical protein RL4127 16 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 116251970 Nonpathogen - hypothetical protein RL2214 2 None None None 116252821 Common - putative polysaccharide synthesis protein RL3077 82 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116251037 Common betA choline dehydrogenase RL1270 96 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 116249962 Nonpathogen - putative transmembrane protein RL0195 2 None None None 116253442 Nonpathogen - putative transmembrane protein RL3702 1 None None None 116251114 Common cycP putative cytochrome c' RL1346 8 COG3909 COG3909, Cytochrome c556 Energy production and conversion 116250921 Common - hypothetical protein RL1151 40 COG5361 COG5361, Uncharacterized conserved protein Function unknown 116250257 Nonpathogen - hypothetical protein RL0486 2 None None None 116252198 Common hyuA putative hydantoin utilization protein A RL2446 118 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116252101 Common - putative ATP-binding component of ABC transporter RL2348 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116253026 Common - putative transmembrane protein RL3283 3 COG4541 COG4541, Predicted membrane protein Function unknown 116250228 Common - putative transposase RL0457 53 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 116252032 Common - putative transmembrane protein RL2276 14 COG5591 COG5591, Uncharacterized conserved protein Function unknown 116253854 Common glgA glycogen synthase RL4117 131 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 116250178 Common - putative transmembrane two-component sensor histidine kinase/response regulator hybrid RL0409 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253219 Common - hypothetical protein RL3477 17 COG5611 COG5611, Predicted nucleic-acid-binding protein, contains PIN domain General function prediction only 116250006 Common - hypothetical protein RL0239 22 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 116253502 Common - hypothetical protein RL3761 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 116249948 Common - putative transmembrane component of ABC transporter RL0181 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116252268 Common - hypothetical protein RL2522 3 None None None 116252709 Nonpathogen - hypothetical protein RL2962 1 COG1359 COG1359, Uncharacterized conserved protein Function unknown 116254157 Common - putative acyltransferase RL4425 38 COG3176 COG3176, Putative hemolysin General function prediction only 116250847 Common - hypothetical protein RL1074 31 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 116250309 Common - hypothetical protein RL0537 45 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 116253466 Common - putative FNR-like transcriptional regulator RL3726 114 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 116251691 Common - putative adhesin autotransporter RL1927 29 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116254193 Common - putative decarboxylase RL4462 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 116251313 Common cvpA putative colicin V production protein RL1547 24 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 116252672 Common mutT putative mutator MutT protein RL2925 77 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 116252476 Common mobB putative molybdopterin-guanine dinucleotide biosynthesis protein B RL2730 107 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 116249999 Common - hypothetical protein RL0232 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 116251110 Common - putative AraC family transcriptional regulator RL1342 105 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250286 Common - putative alcohol dehydrogenase RL0515 200 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 116253498 Common - hypothetical protein RL3757 14 None None None 116253554 Common - putative kinase RL3813 91 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116250176 Common maeB malic enzyme RL0407 215 COG0281 SfcA, Malic enzyme Energy production and conversion 116252067 Nonpathogen - hypothetical protein RL2314 1 None None None 116250621 Nonpathogen - putative transmembrane protein RL0848 1 None None None 116250688 Common - hypothetical protein RL0914 70 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 116250047 Nonpathogen - putative transmembrane protein RL0279 2 COG2246 COG2246, Predicted membrane protein Function unknown 116254394 Nonpathogen - hypothetical protein RL4669 1 None None None 116253945 Common - putative TetR family transcriptional regulator RL4208 87 COG1309 AcrR, Transcriptional regulator Transcription 116252954 Common - putative alcohol dehydrogenase RL3212 196 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 116253610 Common - phosphoribosyltransferase RL3870 6 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 116253775 Common cheY putative chemotaxis two-component response regulator RL4036 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116251086 Common - putative methyl-accepting chemotaxis protein RL1318 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116251763 Common - putative transmembrane DctM/DctQ TRAP family ABC transporter RL2000 118 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 116251985 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase RL2229 144 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 116250452 Common - bifunctional preprotein translocase subunit SecD/SecF RL0680 220 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 116253192 Common - putative transmembrane protein RL3450 10 None None None 116250578 Nonpathogen - hypothetical protein RL0807 1 None None None 116249932 Common - hypothetical protein RL0165 27 None None None 116250436 Common - putative transmembrane acetyltransferase RL0664 20 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116252239 Common trpD anthranilate phosphoribosyltransferase RL2493 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 116253482 Common - putative solute-binding component of ABC transporter RL3741 89 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 116249776 Common - putative Smr domain protein RL0010 75 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 116249893 Common nusA transcription elongation factor NusA RL0127 221 COG0195 NusA, Transcription elongation factor Transcription 116254005 Common - hypothetical protein RL4268 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 116251463 Nonpathogen - hypothetical protein RL1697 1 None None None 116251022 Common - putative LysR family transcriptional regulator RL1255 126 COG0583 LysR, Transcriptional regulator Transcription 116252995 Common - putative serine protease RL3252 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116251377 Common doc putative phage death on curing protein RL1611 56 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 116252907 Common - conserved hypothetical TPR repeat receptor protein RL3165 96 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 116252617 Nonpathogen - putative transmembrane protein RL2870 4 None None None 116249865 Common - glucuronate isomerase RL0099 60 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 116254115 Common - putative filamentous hemagglutinin adherence factor precursor RL4382 110 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 116250857 Nonpathogen - hypothetical protein RL1085 1 None None None 116253542 Common - putative beta-galactosidase RL3801 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 116251918 Common - hypothetical protein RL2160 9 None None None 116253674 Common - hypothetical protein RL3934 7 None None None 116252579 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase RL2832 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 116250236 Nonpathogen - hypothetical protein RL0465 1 None None None 116251030 Common - putative Rrf2 family transcriptional regulator RL1263 171 COG1959 COG1959, Predicted transcriptional regulator Transcription 116250375 Common exoB hypothetical protein RL0604 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 116251809 Common serS seryl-tRNA synthetase RL2049 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 116251216 Nonpathogen - hypothetical protein RL1450 1 None None None 116253278 Common - putative pyridoxamine oxidase protein RL3536 43 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 116253489 Common - putative ATP-binding component of ABC transporter RL3748 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 116251106 Common pmtA putative phosphatidylethanolamine N-methyltransferase RL1338 166 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116251922 Nonpathogen - hypothetical protein RL2164 1 None None None 116250639 Common glcF putative glycolate oxidase iron-sulfur subunit RL0866 182 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 116254281 Common - putative transmembrane component of ABC transporter RL4554 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116253375 Common - putative ATP-binding and permease component of ABC transporter protein RL3632 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116252664 Common dadA putative D-amino acid dehydrogenase RL2917 91 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116250936 Common - putative HTH family transcriptional regulator RL1168 110 COG0640 ArsR, Predicted transcriptional regulators Transcription 116252768 Common - putative polysaccharidase RL3023 28 None None None 116250070 Common - putative AraC family transcriptional regulator RL0302 119 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250136 Common amaB allantoate amidohydrolase RL0367 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 116251979 Common pyrH uridylate kinase RL2223 221 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 116253233 Common - putative aminotransferase/methyltransferase RL3491 170 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 116254330 Common - putative GntR family transcriptional regulator RL4604 139 COG2188 PhnF, Transcriptional regulators Transcription 116250489 Common - putative conserved hypothetical TPR repeat protein RL0717 53 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 116253396 Common - putative polysaccharide biosynthesis protein RL3654 13 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 116251904 Nonpathogen - putative transmembrane protein RL2146 2 None None None 116252710 Nonpathogen - hypothetical protein RL2963 5 None None None 116252717 Common - hypothetical protein RL2971 5 None None None 116250160 Common lnt apolipoprotein N-acyltransferase RL0391 165 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 116252543 Common - putative solute-binding component of ABC transporter RL2796 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250404 Common araA putative L-arabinose isomerase RL0632 9 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 116249812 Common hisH imidazole glycerol phosphate synthase subunit HisH RL0046 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 116253934 Common - putative transmembrane two-component sensor histidine kinase transcriptional regulatory protein RL4197 202 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116254359 Common - putative transmembrane protein RL4633 131 COG2962 RarD, Predicted permeases General function prediction only 116251893 Nonpathogen - hypothetical protein RL2133 1 None None None 116251182 Common - putative myo-inositol degradation/rhizopine catabolism protein RL1416 66 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116251843 Common - putative acetyltransferase RL2083 18 COG0456 RimI, Acetyltransferases General function prediction only 116250951 Common aacC putative aminoglycoside N(3')-acetyltransferase III RL1183 22 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 116253340 Common - putative DEAD box ATP-dependent RNA helicase protein RL3597 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 116251624 Nonpathogen - hypothetical protein RL1859 12 None None None 116250030 Common - hypothetical protein RL0262 43 COG2346 COG2346, Truncated hemoglobins General function prediction only 116250360 Common - hypothetical protein RL0589 20 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116253067 Common btaA putative S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase RL3326 11 COG5379 BtaA, S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase Lipid metabolism 116250791 Common - putative acetyltransferase RL1018 34 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 116250786 Common - hypothetical protein RL1013 8 None None None 116253138 Common - putative AraC family transcriptional regulator RL3396 98 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 116250674 Common - putative inositol monophosphate family protein RL0900 186 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116251010 Common - hypothetical protein RL1243 7 None None None 116251370 Common cumA putative multicopper oxidase RL1604 125 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 116252969 Common - hypothetical protein RL3227 51 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116250366 Common cspA putative cold shock protein RL0595 177 COG1278 CspC, Cold shock proteins Transcription 116254034 Common secA preprotein translocase subunit SecA RL4298 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 116249955 Common - putative ATP-binding component of ABC transporter RL0188 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 116253828 Common - putative inositol mono-phosphatase family protein RL4091 177 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116249830 Common - hypothetical protein RL0064 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 116254065 Common ftsE putative cell division ATP-binding protein RL4330 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 116250480 Common flgC flagellar basal body rod protein FlgC RL0708 119 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 116251059 Common - putative arylesterase RL1292 184 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116254463 Common trmE tRNA modification GTPase TrmE RL4739 214 COG0486 ThdF, Predicted GTPase General function prediction only 116249844 Common exoB putative UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) RL0078 231 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 116251882 Nonpathogen - putative transmembrane protein RL2122 1 None None None 116252696 Common - putative repetitive exported protein RL2949 110 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 116252381 Common - putative LysE family transporter RL2635 124 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116253141 Common - putative proline rich protein RL3399 5 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 116254388 Common - hypothetical protein RL4663 4 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 116250210 Common - putative vitamin B12 binding methyltransferase RL0441 86 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 116254372 Common - putative ATP-binding component of ABC transporter RL4647 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250200 Nonpathogen - putative plasmid stability protein RL0431 1 None None None 116250334 Nonpathogen - hypothetical protein RL0563 2 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116251128 Common ptrB putative protease II RL1360 109 COG1770 PtrB, Protease II Amino acid transport and metabolism 116252652 Nonpathogen - hypothetical protein RL2905 3 None None None 116251824 Common - putative methyltransferase RL2064 80 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 116253416 Nonpathogen - hypothetical protein RL3675 1 None None None 116253212 Common - putative GGDEF/EAL transmembrane sensory box protein RL3470 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116253898 Common - hypothetical protein RL4161 32 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 116254340 Common rpoH2 RNA polymerase factor sigma-32 RL4614 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 116250424 Common - putative LacI family transcriptional regulator RL0652 127 COG1609 PurR, Transcriptional regulators Transcription 116253339 Common - hypothetical protein RL3596 36 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 116253912 Common - putative LacI family transcriptional regulator RL4175 127 COG1609 PurR, Transcriptional regulators Transcription 116251017 Nonpathogen - hypothetical protein RL1250 1 None None None 116250150 Common hrcA heat-inducible transcription repressor RL0381 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 116251298 Common - putative phosphatidylserine synthase RL1532 154 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 116250737 Common - putative transmembrane/surface protein RL0963 7 None None None 116251874 Common - hypothetical protein RL2115 28 COG4544 COG4544, Uncharacterized conserved protein Function unknown 116253679 Common - putative phage-related protein RL3939 8 None None None 116252860 Common - putative GntR family transcriptional regulator RL3118 222 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 116252513 Common ssuB putative aliphatic sulfonates transport ATP-binding component of ABC transporter RL2767 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 116251706 Nonpathogen - hypothetical protein RL1942 10 None None None 116253084 Common parA putative partition-related protein RL3343 57 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 116252699 Common - putative transmembrane rhomboid family protein RL2952 122 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 116250874 Common - hypothetical protein RL1102 23 COG3586 COG3586, Uncharacterized conserved protein Function unknown 116250077 Common - hypothetical protein RL0309 78 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 116253368 Common - putative transmembrane component of ABC transporter RL3625 109 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 116250495 Common motB flagellar motor protein MotB RL0723 87 COG1360 MotB, Flagellar motor protein Cell motility and secretion 116251678 Common - putative transmembrane protein RL1914 78 None None None 116251614 Common - putative epoxide hydrolase RL1848 37 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116252111 Common - putative alcohol dehydrogenase RL2359 177 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116254239 Common - hypothetical protein RL4512 119 COG1733 COG1733, Predicted transcriptional regulators Transcription 116251743 Common - putative transcriptional regulator RL1980 30 COG3806 ChrR, Transcriptional activator Transcription 116253361 Common - putative LysR family transcriptional regulator RL3618 164 COG0583 LysR, Transcriptional regulator Transcription 116252869 Common - hypothetical protein RL3127 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 116249863 Common - Pyruvate dehydrogenase phosphatase regulatory subunit. RL0097 183 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 116253858 Common - putative glyoxylase RL4121 61 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116253980 Common - putative transmembrane component of ABC transporter RL4243 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116251491 Common - DNA polymerase IV RL1725 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 116252826 Nonpathogen - hypothetical protein RL3083 5 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116249807 Common hisE phosphoribosyl-ATP pyrophosphatase RL0041 178 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 116251800 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein RL2040 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 116252043 Common - putative guanine/cytosine deaminase RL2287 15 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 116250914 Nonpathogen - hypothetical protein RL1144 2 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 116253869 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL4132 36 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 116253307 Common - putative sensory box HD domain protein RL3565 23 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 116250798 Common coxZ cytochrome C oxidase assembly protein RL1025 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 116251159 Common - putative N-terminal transmembrane anchored protein RL1391 12 COG5436 COG5436, Predicted integral membrane protein Function unknown 116252218 Common - hypothetical protein RL2471 72 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 116251247 Nonpathogen - hypothetical protein RL1481 2 None None None 116250695 Common - putative cationic transport protein RL0921 157 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 116252704 Common uvrB excinuclease ABC subunit B RL2957 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 116250092 Common - hypothetical protein RL0324 123 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 116251367 Common - hypothetical protein RL1601 33 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 116250823 Common - hypothetical protein RL1050 13 None None None 116254198 Common - putative ATP-binding component of ABC transporter RL4467 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 116250386 Common - hypothetical protein RL0614 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 116253985 Common lacZ putative beta-galactosidase RL4248 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 116251807 Common tatB sec-independent translocase RL2047 29 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 116250443 Common - putative transmembrane protein RL0671 187 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 116252323 Common - hypothetical protein RL2577 133 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 116253660 Common - putative phage-related protein RL3920 42 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 116252174 Common - putative HTH-type transcriptional regulator RL2422 125 COG1609 PurR, Transcriptional regulators Transcription 116253604 Common - putative mandelate racemase/muconate lactonising family protein RL3864 114 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116250207 Common - putative lysine decarboxylase family protein RL0438 105 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 116250465 Common cheD putative chemotaxis related protein RL0693 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 116250776 Common - putative transmembrane component of ABC transporter RL1003 38 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 116254055 Common etfA putative electron transfer flavoprotein alpha-subunit RL4320 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 116252059 Common ccdA putative cytochrome c-type biogenesis protein RL2303 158 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 116251493 Nonpathogen - hypothetical protein RL1727 8 None None None 116253533 Common - putative hydroxypyruvate isomerase RL3792 88 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 116253889 Common cysE putative serine acetyltransferase RL4152 210 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 116250634 Common - putative alcohol dehydrogenase RL0861 173 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116253228 Common petA putative ubiquinol-cytochrome c reductase iron-sulfur subunit RL3486 104 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 116253882 Common - putative LacI family HTH-type transcriptional repressor RL4145 127 COG1609 PurR, Transcriptional regulators Transcription 116249782 Common - putative FAA hydrolase family protein RL0016 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 116250765 Common matB malonyl-CoA synthase RL0991 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116254020 Common ptsP putative phosphoenolpyruvate phosphotransferase RL4283 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 116252490 Common deoC putative deoxyribose-phosphate aldolase RL2744 129 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 116252257 Common pyrG CTP synthetase RL2511 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 116253403 Common exoP putative succinoglycan biosynthesis transport protein RL3662 148 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 116251066 Common - putative cold shock protein RL1299 3 None None None 116253454 Common - putative phytochrome/sensor histidine kinase RL3714 54 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 116252679 Common - putative Acyl-CoA hydrolase RL2932 132 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 116253484 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL3743 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116252256 Common - hypothetical protein RL2510 35 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116252315 Nonpathogen - hypothetical protein RL2569 1 None None None 116250345 Common - hypothetical protein RL0574 47 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 116254421 Common dnaE putative DNA polymerase III alpha subunit RL4697 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 116253965 Common - putative epimerase RL4228 30 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 116250858 Common ppdK pyruvate phosphate dikinase RL1086 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 116253665 Nonpathogen - hypothetical protein RL3925 1 None None None 116251150 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL1382 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116250140 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase RL0371 197 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116252371 Common - hypothetical protein RL2625 32 COG0433 COG0433, Predicted ATPase General function prediction only 116253891 Common - hypothetical protein RL4154 55 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 116251084 Common tam putative trans-aconitate 2-methyltransferase RL1316 61 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 116252169 Common - hypothetical protein RL2417 28 COG1409 Icc, Predicted phosphohydrolases General function prediction only 116253939 Common - putative transmembrane protein RL4202 40 COG4291 COG4291, Predicted membrane protein Function unknown 116251771 Common - hypothetical protein RL2008 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 116254246 Common - putative ATP-binding component of ABC transporter RL4519 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 116251681 Common - hypothetical protein RL1917 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 116253564 Common - putative exopolysacchride production protein RL3823 52 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 116250723 Common - putative methyl-accepting chemotaxis protein RL0949 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116251447 Common - putative transmembrane GGDEF sensory box protein RL1681 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 116251916 Common - hypothetical protein RL2158 20 COG5293 COG5293, Uncharacterized protein conserved in bacteria Function unknown 116253086 Common - putative aldehyde dehydrogenase RL3345 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116252299 Nonpathogen - hypothetical protein RL2553 3 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 116253987 Common - putative transmembrane component of ABC transporter RL4250 165 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116253991 Common - putative transcriptional regulator RL4254 170 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 116250768 Common - putative tartrate dehydrogenase RL0995 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 116253652 Nonpathogen - hypothetical protein RL3912 3 None None None 116253095 Common - hypothetical protein RL3354 18 None None None 116252076 Common - putative GFO/IDH/MocA dehydrogenase RL2323 93 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116252706 Nonpathogen - hypothetical protein RL2959 1 None None None 116253561 Common - putative exopolysaccharide production protein RL3820 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 116250761 Common - hypothetical protein RL0987 12 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116251734 Common - putative flavin reductase RL1970 58 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 116252026 Common - putative nodulin-related transmembrane protein RL2270 75 COG1814 COG1814, Uncharacterized membrane protein Function unknown 116251306 Common - hypothetical protein RL1540 69 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116252659 Common - hypothetical protein RL2912 40 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116250009 Common wbbJ putative lipopolysaccharide biosynthesis O-acetyl transferase pRL0241A 58 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116252446 Common - phosphoglycolate phosphatase RL2699 175 COG0546 Gph, Predicted phosphatases General function prediction only 116251117 Common - putative acetyltransferase RL1349 42 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116253388 Common - putative transmembrane polysaccharide synthesis protein RL3646 80 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116250616 Common - putative ribosomal RNA methyltransferase/cell division FtsJ protein RL0843 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 116251838 Nonpathogen - hypothetical protein RL2078 8 None None None 116250112 Common - putative AsnC family transcriptional regulatory protein RL0344 129 COG1522 Lrp, Transcriptional regulators Transcription 116251325 Common acpP acyl carrier protein RL1559 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116250556 Common - putative d-amino acid dehydrogenase small subunit RL0784 136 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116253579 Common - putative transmembrane dehydrogenase/oxidoreductase RL3838 216 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116250002 Common - putative transmembrane exopolysaccharide biosynthesis protein RL0235 5 None None None 116251796 Common - putative outer membrane transport protein RL2036 41 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 116252353 Common kptA putative RNA 2'-phosphotransferase RL2607 44 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 116252747 Common dapB putative dihydrodipicolinate reductase RL3002 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 116253191 Common cspA putative cold shock protein RL3449 178 COG1278 CspC, Cold shock proteins Transcription 116249820 Common glcB malate synthase G RL0054 83 COG2225 AceB, Malate synthase Energy production and conversion 116251328 Common - hypothetical protein RL1562 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 116253127 Common - hypothetical protein RL3385 133 COG0432 COG0432, Uncharacterized conserved protein Function unknown 116249825 Common - putative ATP-dependent helicase protein RL0059 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 116250313 Common - hypothetical protein RL0541 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 116253177 Common - putative LysR family transcriptional regulator RL3435 169 COG0583 LysR, Transcriptional regulator Transcription 116252807 Common - hypothetical protein RL3063 7 COG4088 COG4088, Predicted nucleotide kinase Nucleotide transport and metabolism 116251193 Common - hypothetical protein RL1427 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 116253172 Common - putative ArsR family transcriptional regulator RL3430 53 COG0640 ArsR, Predicted transcriptional regulators Transcription 116253459 Common - hypothetical protein RL3719 21 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 116254366 Common - putative Beta-(1-->2) glucan export ATP-binding component of ABC transporter RL4640 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 116251857 Common hom homoserine dehydrogenase RL2097 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 116249929 Common - hypothetical protein RL0162 43 COG2320 GrpB, Uncharacterized conserved protein Function unknown 116250836 Common - hypothetical protein RL1063 11 None None None 116250470 Common - hypothetical protein atu0565/agr_c_992 RL0698 9 None None None 116249816 Common - putative Mutant AAC6'-IbY166A 6'-N-acetyltransferase. RL0050 20 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 116251045 Common - hypothetical protein RL1278 53 COG2345 COG2345, Predicted transcriptional regulator Transcription 116252504 Common - hypothetical protein RL2758 27 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 116252116 Common - putative transmembrane efflux protein RL2364 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 116250039 Common - hypothetical protein RL0271 10 None None None 116254185 Common - putative component of ABC transporter RL4454 20 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116251950 Common - hypothetical protein RL2193 19 None None None 116252582 Common - gluconate 5-dehydrogenase RL2835 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250869 Common hsdS putative type I restriction enzyme specificity subunit RL1097 81 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 116250885 Common - putative transcriptional regulator RL1113 14 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116253486 Common - putative solute-binding component of ABC transporter RL3745 132 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 116252822 Common - hypothetical protein RL3078 2 None None None 116253344 Nonpathogen - hypothetical protein RL3601 6 None None None 116251206 Common degP putative serine protease RL1440 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 116253623 Common ade putative adenine deaminase RL3883 85 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 116250987 Common - hypothetical protein RL1220 27 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 116251259 Common iolE putative rhizopine catabolism protein RL1493 65 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116253873 Common pntAA putative NAD(P) transhydrogenase subunit alpha part 1 RL4136 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 116253311 Common bdhA putative D-beta-hydroxybutyrate dehydrogenase RL3569 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250873 Nonpathogen - hypothetical protein RL1101 1 None None None 116254078 Common - hypothetical protein RL4343 15 None None None 116254354 Common ispA putative geranyltranstransferase RL4628 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 116250290 Common fucU2 putative fucose operon protein RL0519 33 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 116252525 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2779 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116253161 Common carB carbamoyl phosphate synthase large subunit RL3419 233 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 116252404 Common - hypothetical protein RL2658 28 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 116254455 Common - putative racemase RL4731 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 116251602 Common - putative transmembrane two-component kinase RL1836 132 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 116251056 Nonpathogen - hypothetical protein RL1289 7 None None None 116252012 Common ntrB two-component sensor histidine kinase nitrogen regulatory protein RL2256 211 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 116253676 Nonpathogen - hypothetical protein RL3936 2 None None None 116249942 Common phnI putative phosphonate metabolism protein RL0175 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 116254153 Common ilvD dihydroxy-acid dehydratase RL4421 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 116252694 Common - hypothetical protein RL2947 12 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 116253198 Nonpathogen - putative transmembrane protein RL3456 1 None None None 116250590 Common - putative lipopolysaccharide synthesis protein RL0818 22 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 116251440 Common - putative LysR family transcriptional regulator RL1674 192 COG0583 LysR, Transcriptional regulator Transcription 116254095 Common - putative cobalamin synthesis protein RL4362 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 116251436 Common - putative transmembrane efflux protein RL1670 175 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253135 Common - hypothetical protein RL3393 52 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 116250154 Common - hypothetical protein RL0385 13 COG5568 COG5568, Uncharacterized small protein Function unknown 116251190 Common - putative LysR family transcriptional regulator RL1424 169 COG0583 LysR, Transcriptional regulator Transcription 116251061 Common lig ATP-dependent DNA ligase RL1294 101 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 116250878 Common - putative PspA family regulator RL1106 23 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 116250843 Nonpathogen - hypothetical protein RL1070 1 None None None 116252911 Common - putative hydrolase RL3169 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 116253807 Common pabB para-aminobenzoate synthase component I RL4069 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 116252872 Common - putative phosphatase protein RL3130 178 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 116252937 Common - hypothetical protein RL3195 44 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116253182 Common gspA putative general stress protein A RL3440 20 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 116252376 Common - hypothetical protein RL2630 2 None None None 116252952 Common - putative glucosyl transferase RL3210 160 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116253608 Nonpathogen - hypothetical protein RL3868 2 None None None 116252925 Common - putative transmembrane protein RL3183 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 116254013 Nonpathogen - hypothetical protein RL4276 2 None None None 116250384 Common - hypothetical protein RL0612 21 None None None 116250667 Common - hypothetical protein RL0893 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 116252009 Common - putative competence/damage inducible protein RL2253 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 116252183 Common - hypothetical protein RL2430A 3 None None None 116251853 Common - hypothetical protein RL2093 11 None None None 116253680 Common - hypothetical protein RL3940 3 None None None 116254032 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein RL4296 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 116254409 Common - putative solute-binding component of ABC transporter RL4685 126 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 116250599 Common - putative insertion sequence-related protein RL0827 10 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116250861 Nonpathogen - hypothetical protein RL1089 2 None None None 116254269 Common ispZ intracellular septation protein A RL4542 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 116251286 Nonpathogen - hypothetical protein RL1520 1 None None None 116250271 Common - putative TetR family transcriptional regulator RL0500 56 COG1309 AcrR, Transcriptional regulator Transcription 116252680 Common - putative transmembrane protein RL2933 7 None None None 116250943 Common - putative transmembrane efflux protein RL1175 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 116252292 Common - putative transmembrane acyltransferase RL2546 85 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 116254164 Common - hypothetical protein RL4432 6 None None None 116251262 Common - putative sugar isomerase family protein RL1496 55 COG1737 RpiR, Transcriptional regulators Transcription 116251410 Common - hypothetical protein RL1644 12 None None None 116252172 Common - putative transmembrane component of ABC transporter RL2420 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116250224 Common - putative methyl-accepting chemotaxis protein RL0455 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116253169 Common - putative AsnC family transcriptional regulatory protein RL3427 154 COG1522 Lrp, Transcriptional regulators Transcription 116254271 Common - putative methylase RL4544 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 116250903 Common - putative transmembrane protein RL1131 58 COG0730 COG0730, Predicted permeases General function prediction only 116252640 Common - putative two-component sensor histidine kinase transcriptional regulatory protein RL2893 160 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 116251419 Nonpathogen - hypothetical protein RL1653 1 None None None 116250809 Common - hypothetical protein RL1036 56 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 116253299 Common bacA transport protein RL3557 59 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 116253920 Common - putative transmembrane protein RL4183 117 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 116250370 Common - putative transmembrane efflux protein RL0599 43 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116250813 Common - putative LysR family transcriptional regulatory protein RL1040 174 COG0583 LysR, Transcriptional regulator Transcription 116253284 Common aglA putative alpha-glucosidase RL3542 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 116252147 Common - putative transmembrane protein RL2395 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 116254177 Common sdhD putative succinate dehydrogenase hydrophobic membrane anchor protein RL4445 40 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 116254339 Common - putative peptidase RL4613 130 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 116252142 Common - putative invasion-associated protein RL2390 15 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 116253116 Nonpathogen - hypothetical protein RL3374A 1 None None None 116252635 Common arsH putative arsenic resistance protein RL2888 67 COG0431 COG0431, Predicted flavoprotein General function prediction only 116253333 Common - hypothetical protein RL3590 71 COG4121 COG4121, Uncharacterized conserved protein Function unknown 116253040 Common ftsA putative cell division protein FtsA RL3299 183 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 116254054 Common etfB putative electron transfer flavoprotein beta-subunit RL4319 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 116250379 Common - hypothetical protein RL0608 3 None None None 116254251 Common rpoE putative ECF RNA polymerase sigma-70 family RL4524 156 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 116252979 Nonpathogen - hypothetical protein RL3237 8 None None None 116254322 Common - putative acyl CoA dehydrogenase RL4596 56 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 116250606 Nonpathogen - putative transmembrane protein RL0834 1 None None None 116250648 Common - hypothetical protein RL0875 45 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 116249881 Common irr iron response regulator RL0115 147 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 116252775 Common - putative transmembrane efflux protein RL3030 157 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116251516 Common dhaL1 putative PTS-dependent dihydroxyacetone kinase,ADP-binding subunit RL1750 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116253349 Nonpathogen - hypothetical protein RL3606 1 None None None 116251740 Common - hypothetical protein RL1976 30 None None None 116251644 Common - putative nitrogen fixation two component sensor/regulator fusion transcriptional regulator RL1879 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 116252536 Common - putative oxidoreductase protein RL2789 190 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 116252899 Common - putative monooxygenase RL3157 9 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 116250102 Common dnaN DNA polymerase III subunit beta RL0334 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 116254090 Common sirA putative transcriptional regulator RL4357 101 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116253103 Common metH B12-dependent methionine synthase RL3362 176 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 116254008 Common - putative short-chain dehydrogenase/reductase RL4271 228 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 116253038 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase RL3297 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 116252405 Common - putative solute-binding component of ABC transporter RL2659 110 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 116253601 Common - putative transmembrane component of ABC transporter RL3861 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 116250980 Common - hypothetical protein RL1213 64 COG3832 COG3832, Uncharacterized conserved protein Function unknown 116250204 Common - putative transmembrane protein RL0435 6 None None None 116250497 Common motD putative chemotaxis MotD protein (motility protein D) RL0725 6 None None None 116252089 Common uxuA putative mannonate dehydratase RL2336 57 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 116253168 Common dctD putative C4-dicarboxylate transport two-component response regulator sigma 54 transcriptional regulatory protein RL3426 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116254132 Nonpathogen - hypothetical protein RL4399 4 None None None 116253399 Common prsE putative HlyD family secretion protein RL3657 119 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116250535 Common - putative putrescine-binding periplasmic component of ABC transporter RL0763 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 116251178 Common groS5 putative 10 kda chaperonin 5 (GroES protein 5) RL1410 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 116254379 Common - putative ATP-binding component of ABC transporter RL4654 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116253203 Common - hypothetical protein RL3461 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 116253687 Nonpathogen - hypothetical protein RL3947 1 None None None 116254262 Common - hypothetical protein RL4535 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 116253647 Common - putative transmembrane component of ABC transporter RL3907 133 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 116251523 Common tufB1 elongation factor Tu RL1757 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 116251004 Common - putative arylsulfatase RL1237 73 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 116250893 Nonpathogen - hypothetical protein RL1121 2 None None None 116254445 Common - putative transmembrane protein RL4721 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 116250751 Common - putative histone deacetylase-like amidohydrolase RL0977 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 116253428 Common - putative transmembrane efflux protein RL3687 137 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 116251293 Common - hypothetical protein RL1527 6 None None None 116252416 Common - putative LysR family transcriptional regulator RL2669 150 COG0583 LysR, Transcriptional regulator Transcription 116249851 Common - putative glycerate dehydrogenase RL0085 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 116251754 Common nasD putative assimilatory siroheme nitrite reductase [NAD(P)H] RL1991 199 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 116253239 Common - putative NUDIX/MutT family protein RL3497 129 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 116252348 Common - putative transmembrane protein RL2602 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 116250479 Common flgB flagellar basal body rod protein FlgB RL0707 33 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 116253822 Common gltA putative glutamate synthase [NADPH] large chain RL4085 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 116251089 Common - hypothetical protein RL1320A 18 COG0645 COG0645, Predicted kinase General function prediction only 116249974 Common deoB phosphopentomutase RL0207 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 116249817 Common hslU ATP-dependent protease ATP-binding subunit RL0051 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 116250284 Common - putative transcriptional regulator RL0513 142 COG0583 LysR, Transcriptional regulator Transcription 116250189 Common - putative outer membrane OstA family protein RL0420 26 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 116252123 Common qor putative quinone oxidoreductase RL2371 196 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116254035 Common - putative polysaccharide export related protein RL4299 31 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 116251871 Nonpathogen - hypothetical protein RL2110 4 None None None 116250522 Common - hypothetical protein RL0750 3 None None None 116251224 Common - hypothetical protein RL1458 66 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 116250021 Common gfa putative glutathione-dependent formaldehyde-activating enzyme RL0253 48 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116253815 Common - putative transmembrane protein RL4078 46 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116254404 Common - putative phosphatase RL4680 21 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 116250514 Common - putative transmembrane succinoglycan biosynthesis transport protein RL0742 10 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 116251484 Common - putative transmembrane protein RL1718 17 COG5454 COG5454, Predicted secreted protein Function unknown 116254311 Common pcd putative piperideine-6-carboxylate dehydrogenase RL4585 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 116250149 Common rph ribonuclease PH RL0380 186 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 116250730 Common ubiA prenyltransferase RL0956 169 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 116252843 Common - putative PadR family transcriptional regulator RL3102 61 COG1695 COG1695, Predicted transcriptional regulators Transcription 116251560 Common secY preprotein translocase subunit SecY RL1794 219 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 116252214 Common - hypothetical protein RL2463 38 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 116253998 Common nrdH putative glutaredoxin-like protein RL4261 34 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 116250573 Common - putative deoxygenase RL0802 13 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 116254294 Common ubiF 2-octaprenyl-6-methoxyphenyl hydroxylase RL4568 133 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 116252753 Common - putative phosphonate uptake related protein RL3008 18 None None None 116251330 Common ksgA dimethyladenosine transferase RL1564 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 116253254 Common - hypothetical protein RL3512 132 COG1733 COG1733, Predicted transcriptional regulators Transcription 116252647 Common dhaK putative dihydroxyacetone kinase RL2900 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116254303 Common - putative transmembrane permease component of ABC transporter RL4577 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116251937 Common - putative helix-turn-helix transcriptional regulatory protein RL2180 27 COG1396 HipB, Predicted transcriptional regulators Transcription 116250355 Common - hypothetical protein RL0584 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 116254048 Common - putative DNA-3-methyladenine glycosylase RL4312 106 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 116251695 Nonpathogen - hypothetical protein RL1931 1 None None None 116254234 Common - putative acetyltransferase RL4505 66 COG0456 RimI, Acetyltransferases General function prediction only 116249837 Common - Hypothetical protein expD2. RL0071 115 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 116251634 Common - putative cation-transporting ATPase RL1869 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 116251476 Common nqo10 NADH dehydrogenase subunit J RL1710 69 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 116251729 Common - putative AsnC family transcriptional regulator RL1965 153 COG1522 Lrp, Transcriptional regulators Transcription 116250745 Common - hypothetical protein RL0971 9 None None None 116252220 Common metG methionyl-tRNA synthetase RL2473 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116251321 Common rpsF 30S ribosomal protein S6 RL1555 199 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 116252228 Common - putative transmembrane GGDEF family sensory box protein RL2481 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 116252649 Common - putative PTS-dependent dihydroxyacetone kinase,phosphotransferase subunit RL2902 44 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 116250839 Nonpathogen - putative transmembrane protein RL1066 1 None None None 116251024 Common qor putative quinone oxidoreductase RL1257 188 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 116253245 Common - putative acetyltransferase RL3503 30 COG3393 COG3393, Predicted acetyltransferase General function prediction only 116251784 Common phaZ putative poly(3-hydroxyalkanoate) depolymerase C precursor RL2023 30 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 116251957 Common aapP General L-amino acid transport ATP-binding subunit RL2201 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 116252598 Common - hypothetical protein RL2851 91 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 116252762 Common - putative exported molybdopterin cofactor-containing protein RL3017 131 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 116251341 Common - putative prolyl endopeptidase RL1575 113 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 116251612 Common - putative two component response regulator transcriptional regulatory protein RL1846 140 COG4566 TtrR, Response regulator Signal transduction mechanisms 116250894 Common - putative GerE/LuxR family transcriptional regulator RL1122 58 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 116253032 Common - putative DNA polymerase/exonuclease RL3291 106 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 116250973 Nonpathogen - hypothetical protein RL1206 3 None None None 116254040 Common - putative transmembrane transport protein RL4304 94 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 116253552 Common - putative transmembrane component of ABC transporter RL3811 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116251723 Common acpD putative acyl carrier protein phosphodiesterase RL1959 97 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 116252930 Nonpathogen - hypothetical protein RL3188 1 None None None 116254414 Common - hypothetical protein RL4690 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 116251542 Common rplW 50S ribosomal protein L23 RL1776 228 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 116252065 Nonpathogen - hypothetical protein RL2309 1 None None None 116252495 Common - putative transmembrane component of ABC transporter RL2749 179 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116253273 Nonpathogen - hypothetical protein RL3531 4 None None None 116249910 Common - putative Pfk family kinase RL0143 156 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116251356 Common - putative glutathione S-transferase RL1590 63 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116253263 Common trpE putative anthralinate synthase protein RL3521 239 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 116253303 Common - putative bacterial luciferase family protein RL3561 58 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 116252125 Common - putative transmembrane component of ABC transporter RL2373 123 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 116253290 Common kdgK putative 2-dehydro-3-deoxygluconokinase RL3548 102 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116250506 Common fliQ flagellar biosynthesis protein FliQ RL0734 126 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 116253145 Common - hypothetical protein RL3403 57 COG3791 COG3791, Uncharacterized conserved protein Function unknown 116253640 Nonpathogen - hypothetical protein RL3900 1 None None None 116253694 Nonpathogen - hypothetical protein RL3954 1 None None None 116251387 Common ribD putative riboflavin biosynthesis protein RL1621 219 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 116254060 Common lysA putative diaminopimelate decarboxylase RL4325 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 116252387 Common - hypothetical protein RL2641 4 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 116252365 Common - putative acetyltransferase RL2619 60 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 116254219 Common - hypothetical protein RL4490 68 COG3897 COG3897, Predicted methyltransferase General function prediction only 116252552 Common - putative acetyltransferase RL2805 89 COG3153 COG3153, Predicted acetyltransferase General function prediction only 116253929 Common - putative transmembrane component of ABC transporter RL4192 221 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116252242 Common moeA putative molybdopterin biosynthesis protein RL2496 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 116250015 Nonpathogen - hypothetical protein RL0247 1 None None None 116254195 Common - putative lyase/mutase RL4464 102 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 116252045 Common - hypothetical protein RL2289 7 None None None 116252475 Common mobA putative molybdopterin-guanine dinucleotide biosynthesis protein A RL2729 82 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 116253449 Common ftrA transcriptional activator FtrA RL3709 115 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 116250372 Common - putative transmembrane two-component sensor kinase/regulator hybrid RL0601 227 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 116250735 Common - hypothetical protein RL0961 3 None None None 116251650 Common - putative beta-lactamase family protein RL1885 128 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 116250105 Common - hypothetical protein RL0337 22 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 116251646 Common - putative two-component regulator response regulator transcriptional regulatory protein RL1881 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116250302 Nonpathogen - putative transmembrane protein RL0531 1 None None None 116252150 Common uvrA excinuclease ABC subunit A RL2398 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 116250251 Common - putative TetR family transcriptional regulator RL0480 90 COG1309 AcrR, Transcriptional regulator Transcription 116252867 Common - hypothetical protein RL3125 23 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 116253545 Common - putative ATP-binding component of ABC transporter RL3804 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 116254063 Common hprT putative hypoxanthine-guanine phosphoribosyltransferase RL4328 153 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 116253201 Common csaA putative chaperone protein RL3459 117 COG0073 ARC1, EMAP domain General function prediction only 116253432 Common - hypothetical protein RL3691 40 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 116251486 Common - putative transmembrane component of ABC transporter RL1720 188 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 116252615 Common - hypothetical protein RL2868 45 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 116254210 Common - putative GntR family transcriptional regulator RL4481 24 COG1802 GntR, Transcriptional regulators Transcription 116251887 Nonpathogen - putative transmembrane protein RL2127 1 None None None 116251500 Common rnr putative ribonuclease R RL1734 192 COG0557 VacB, Exoribonuclease R Transcription 116252562 Common fabF2 3-oxoacyl-(acyl carrier protein) synthase II RL2815 163 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116250963 Common - putative adhesin precursor (autotransporter) RL1196 63 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 116253508 Common - putative transmembrane protein RL3767 13 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 116250923 Common - hypothetical protein RL1154 5 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 116249853 Common - hypothetical protein RL0087 28 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116253440 Common hmuV ABC transporter component for haem transport RL3700 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 116253943 Common - putative transmembrane protein RL4206 18 COG5488 COG5488, Integral membrane protein Function unknown 116252196 Common - hypothetical protein RL2444 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 116251711 Common - hypothetical protein RL1947 9 None None None 116251273 Common - hypothetical protein RL1507 3 None None None 116249873 Common cmk cytidylate kinase RL0107 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 116251075 Common - putative outer membrane protein RL1307 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 116253841 Common - putative solute-binding component of ABC transporter RL4104 31 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 116249822 Common - hypothetical protein RL0056 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 116251094 Common ilvE aminotransferase RL1326 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 116253612 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase RL3872 191 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 116251218 Common dnaK putative chaperone protein DnaK (heat shock protein 70) (hsp70) RL1452 230 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 116250198 Common - putative methyl-accepting chemotaxis protein RL0429 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 116249795 Common - hypothetical protein RL0029 205 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 116251032 Common - putative LysR family transcriptional regulator RL1265 131 COG0583 LysR, Transcriptional regulator Transcription 116250575 Common - hypothetical protein RL0804 38 None None None 116253958 Common - putative kinase RL4221 124 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 116250288 Common - putative ATP-binding component of ABC transporter RL0517 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 116254392 Nonpathogen - putative transmembrane protein RL4667 1 None None None 116251189 Common - putative transmembrane protein RL1423 27 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 116252993 Common serB putative phosphoserine phosphatase RL3250 152 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 116254423 Common - hypothetical protein RL4699 10 COG4544 COG4544, Uncharacterized conserved protein Function unknown 116250855 Common - putative disulfide bond formation protein D RL1083 86 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 116253996 Common nrdE ribonucleotide-diphosphate reductase subunit alpha RL4259 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 116250784 Common fabI enoyl-(acyl carrier protein) reductase RL1011 232 COG0623 FabI, Enoyl- acyl-carrier-protein 116252208 Common - putative hydrolase RL2457 89 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116254416 Common ctpA putative carboxy-terminal processing protease precursor RL4692 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 116252904 Common - putative short-chain dehydrogenase/oxidoreductase RL3163 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 116249774 Common - hypothetical protein RL0008 43 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 116253405 Common pssN putative capsule polysaccharide export protein RL3664 81 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 116253682 Nonpathogen - hypothetical protein RL3942 1 None None None 116250362 Common - putative acyl-CoA dehydrogenase RL0591 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 116252233 Common - putative alkylphosphonate uptake related protein RL2487 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 116252303 Nonpathogen - hypothetical protein RL2557 3 None None None 116250336 Common - putative solute-binding component of ABC transporter RL0565 157 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116253276 Common - putative transmembrane component of ABC transporter RL3534 169 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 116251167 Common - short chain dehydrogenase RL1399 91 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116250055 Common - putative glutathione S transferase RL0287 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116251555 Common rplF 50S ribosomal protein L6 RL1789 238 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 116253728 Common ruvA Holliday junction DNA helicase motor protein RL3989 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 116253089 Common - putative N-formylglutamate amidohydrolase family protein RL3348 41 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 116249886 Common pnp polynucleotide phosphorylase/polyadenylase RL0120 243 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 116251509 Common - putative peptidoglycan transglycosylase penicillin-binding protein 1A RL1743 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 116250134 Common - hypothetical protein RL0365 6 None None None 116251039 Common - transcriptional regulator BetI RL1272 43 COG1309 AcrR, Transcriptional regulator Transcription 116250690 Common dgoK putative 2-dehydro-3-deoxygalactonokinase RL0916 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 116250849 Nonpathogen - hypothetical protein RL1076 1 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 116253024 Nonpathogen - putative transmembrane protein RL3281 1 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 116253960 Common - putative Acr/RND family transmembrane transporter RL4223 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 116254212 Common - putative transmembrane component of ABC transporter RL4483 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116250041 Common - putative LysR family transcriptional regulator RL0273 138 COG0583 LysR, Transcriptional regulator Transcription 116253391 Common - putative glycosyltransferase RL3649 128 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 116250655 Common - putative glutathione S-transferase RL0881 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 116252669 Common - putative solute-binding component of ABC transporter RL2922 154 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116252158 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase RL2406 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 116250323 Common hslO Hsp33-like chaperonin RL0551 131 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 116253885 Common - putative cobalamin synthesis protein RL4148 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 116250048 Common - putative glycosyltransferase RL0280 113 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 116251988 Common - hypothetical protein RL2232 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 116250444 Common - hypothetical protein RL0672 38 COG0400 COG0400, Predicted esterase General function prediction only 116252761 Common pcaH protocatechuate 3,4-dioxygenase beta chain (3,4-pcd) RL3016 37 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 116251140 Common - putative monovalent cation/H+ antiporter subunit A RL1372 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 116253123 Common - putative acetyltransferase RL3381 24 COG2153 ElaA, Predicted acyltransferase General function prediction only 116250811 Common - hypothetical protein RL1038 36 COG2128 COG2128, Uncharacterized conserved protein Function unknown 116251416 Common - putative (DL)-glycerol-3-phosphatase RL1650 86 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 116251895 Common - putative transposase-related protein RL2135 18 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 116250711 Common ispB putative octaprenyl-diphosphate synthase RL0937 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 116251264 Common - putative flavoprotein RL1498 235 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 116254343 Common hslR putative heat shock protein 15 RL4617 94 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 116253426 Common - putative GFO/IDH/MocA family oxidoreductase RL3685 160 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 116253862 Common - hypothetical protein RL4125 3 None None None 116251684 Common - hypothetical protein RL1920 26 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 116253325 Common - putative DNA repair protein RL3582 68 COG0622 COG0622, Predicted phosphoesterase General function prediction only 116250392 Common - hypothetical protein RL0620 11 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 116252038 Common ntrX putative two component response regulator nitrogen assimilation regulatory protein RL2282 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 116252293 Common rpiB ribose-5-phosphate isomerase B RL2547 134 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 116253689 Nonpathogen - hypothetical protein RL3948A 2 None None None 116253529 Common - putative serine/threonine protein phosphatase RL3788 83 None None None 116253974 Common - hypothetical protein RL4237 26 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116252835 Common - hypothetical protein RL3092 8 COG5381 COG5381, Uncharacterized protein conserved in bacteria Function unknown 116253619 Common - putative transmembrane component of ABC transporter RL3879 194 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 116252021 Nonpathogen - hypothetical protein RL2265 2 None None None 116253884 Common - hypothetical protein RL4147 83 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 116253936 Nonpathogen - hypothetical protein RL4199 1 None None None 116252857 Common - putative phosphotransferase family protein RL3115 7 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 116252018 Common cya3 putative adenylate cyclase RL2262 28 COG5616 COG5616, Predicted integral membrane protein Function unknown 116250604 Common - putative DNA ligase RL0832 59 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 116251231 Common - hypothetical protein RL1465 59 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 116252850 Common - putative transmembrane component of ABC transporter RL3109 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116250759 Common - putative solute-binding component of ABC transporter RL0985 88 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116252436 Common - putative transmembrane protein RL2689 46 COG4420 COG4420, Predicted membrane protein Function unknown 116250305 Common fixP putative membrane-anchored cbb3 cytochrome oxidase subunit RL0534 81 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 116254134 Common - putative ATP-binding component of ABC transporter RL4401 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 116251336 Common - putative transmembrane protein RL1570 15 None None None 116250230 Common - hypothetical protein RL0459 20 COG5616 COG5616, Predicted integral membrane protein Function unknown 116250940 Common - putative transmembrane protein RL1172 18 COG2261 COG2261, Predicted membrane protein Function unknown 116252266 Common - putative transmembrane protein RL2520 135 COG0628 PerM, Predicted permease General function prediction only 116251180 Nonpathogen - hypothetical protein RL1413 4 None None None 116251229 Common - hypothetical protein RL1463 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 116253003 Common - hypothetical protein RL3260 18 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 116253004 Common - putative FAD-dependent dehydrogenase/oxidoreductase RL3261 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 116253511 Common - putative acetyltransferase RL3770 31 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 116253063 Common pfp pyrophosphate--fructose-6-phosphate 1-phosphotransferase RL3322 130 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 116253522 Nonpathogen - hypothetical protein RL3781 1 None None None 116250586 Common - hypothetical protein RL0814 124 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116251423 Common - putative substrate binding component of ABC transporter RL1657 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 116250533 Common - putative isocitrate lyase RL0761 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 116252813 Nonpathogen - putative transmembrane protein RL3069 1 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 116252572 Common - putative inosine-uridine preferring nucleoside hydrolase RL2825 86 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 116250399 Common - putative GerE family transcriptional regulator RL0627 119 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 116254237 Nonpathogen - hypothetical protein RL4508 1 None None None 116253866 Common cyaB1 putative transmembrane adenylate cyclase RL4129 85 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 116251816 Common - hypothetical protein RL2056 33 COG3737 COG3737, Uncharacterized conserved protein Function unknown 116253518 Common - putative LysR family transcriptional regulator RL3777 150 COG0583 LysR, Transcriptional regulator Transcription 116250100 Common - hypothetical protein RL0332 16 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 116253752 Common - putative phenazine biosynthesis protein RL4013 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 116251456 Common lon putative ATP-dependent protease RL1690 226 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 116253256 Common - putative transmembrane transporter RL3514 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 116251787 Nonpathogen - hypothetical protein RL2026 1 None None None 116253314 Common xdhC putative xanthine dehydrogenase cofactor insertion RL3572 62 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 116253019 Common pcrA putative ATP-dependent DNA helicase RL3276 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 116253723 Common - putative oxidoreductase RL3984 115 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 116254028 Common - putative pilus component protein RL4292 7 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 116250825 Nonpathogen - hypothetical protein RL1052 1 None None None 116251369 Common rnd putative ribonuclease D RL1603 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 116251068 Nonpathogen - hypothetical protein RL1301 1 None None None 116253793 Common - hypothetical protein RL4054 9 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 116251598 Common exoA putative exodeoxyribonuclease RL1832 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 116251360 Common phnM putative phosphonate metabolism protein RL1594 53 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 116251923 Nonpathogen - hypothetical protein RL2165 1 None None None 116254356 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase RL4630 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 116251968 Common clpS ATP-dependent Clp protease adaptor protein ClpS RL2212 120 COG2127 COG2127, Uncharacterized conserved protein Function unknown 116253667 Common - hypothetical protein RL3927 10 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 116249997 Common - endo-type 6-aminohexanoate oligomer hydrolase RL0230 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 116252279 Common - putative patatin family protein RL2533 121 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 116252828 Nonpathogen - hypothetical protein RL3085 3 None None None 116250462 Common cheR putative chemotaxis protein methyltransferase RL0690 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 116250167 Common - putative acetyltransferase RL0398 162 COG0456 RimI, Acetyltransferases General function prediction only 116251818 Common - hypothetical protein RL2058 3 None None None 116253747 Nonpathogen - hypothetical protein RL4008 3 None None None 116252721 Common - putative ATP-binding component of ABC transporter RL2975 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 116251403 Common - hypothetical protein RL1637 29 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 116253215 Common - putative solute-binding component of ABC transporter RL3473 25 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 116252333 Common anmK anhydro-N-acetylmuramic acid kinase RL2587 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 116250632 Common - putative HTH-type transcriptional regulator RL0859 82 COG0583 LysR, Transcriptional regulator Transcription 116253715 Nonpathogen sqdD putative glycosyl transferase (sulfolipid biosynthesis) protein RL3976 5 COG5597 COG5597, Alpha-N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 116250938 Common clpP ATP-dependent Clp protease proteolytic subunit RL1170 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 116253818 Common exoN putative UTP--glucose-1-phosphate uridylyltransferase RL4081 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 116252313 Common rLuC putative ribosomal large subunit pseudouridine synthase C RL2567 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 116253833 Common - hypothetical protein RL4096 8 None None None 116250978 Common - hypothetical protein RL1211 42 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 116252429 Common - putative transmembrane transport protein RL2682 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116253091 Common - putative solute-binding component of ABC transporter RL3350 47 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 116249780 Common - hypothetical protein RL0014 18 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 116252317 Common - hypothetical protein RL2571 4 None None None 116253452 Common - putative LysR family transcriptional regulator RL3712 172 COG0583 LysR, Transcriptional regulator Transcription 116249809 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase RL0043 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 116250542 Nonpathogen - hypothetical protein RL0770 10 COG5490 COG5490, Uncharacterized conserved protein Function unknown 116251991 Common - putative transmembrane DNA uptake competence-related protein RL2235 135 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 116250916 Common - hypothetical protein RL1146 60 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116252733 Common argG putative argininosuccinate synthase RL2987 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 116250028 Common recX recombination regulator RecX RL0260 11 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 116253381 Common - putative peptide antibiotic resistance protein RL3638 13 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 116253362 Common - hypothetical protein RL3619 3 None None None 116254274 Common ffh putative signal recognition particle protein (fifty-four homolog) RL4547 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 116250665 Common - putative nitrogen fixation symbiosis related protein RL0891 198 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 116251119 Common - putative cation efflux system protein RL1351 124 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 116251498 Common - putative transmembrane protein RL1732 71 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 116249924 Common - hypothetical protein RL0157 168 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 116250129 Common - putative LysR family transcriptional regulator RL0360 105 COG0583 LysR, Transcriptional regulator Transcription 116250630 Common pit putative transmembrane inorganic phosphate transporter RL0857 156 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 116253590 Common - putative GntR family transcriptional regulator RL3849 128 COG2186 FadR, Transcriptional regulators Transcription 116250347 Common - putative TPR repeat domain protein RL0576 31 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 116251564 Common rpoA DNA-directed RNA polymerase subunit alpha RL1798 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 116250549 Common rirA iron-responsive transcriptional regulator RL0777 161 COG1959 COG1959, Predicted transcriptional regulator Transcription 116250079 Common - putative DJ-1/PfPI family protein RL0311 117 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 116252603 Common argO putative transmembrane lysine/arginine export protein RL2856 79 COG1279 COG1279, Lysine efflux permease General function prediction only 116252259 Common tpiA putative triosephosphate isomerase RL2513 218 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 116252145 Common glnB putative nitrogen regulatory protein p-II RL2393 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 116252164 Common - putative calcium binding protein RL2412 56 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 116252057 Common - putative ionic voltage-gated channel protein RL2301 15 None None None 116251399 Common nusB transcription antitermination protein NusB RL1633 183 COG0781 NusB, Transcription termination factor Transcription 116252459 Common - putative ubiquinone/menaquinone biosynthesis methyltransferase RL2712 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 116250763 Common - putative GntR family transcriptional regulator RL0989 122 COG1802 GntR, Transcriptional regulators Transcription 116252211 Common - hypothetical protein RL2460 114 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 116249934 Common phoE putative permease component of phosphate uptake ABC transporter RL0167 87 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 116249940 Common phnK phosphonates transport ATP-binding protein RL0173 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 116252328 Common sufB cysteine desulfurase activator complex subunit SufB RL2582 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 116253963 Common osmC putative osmotically inducible protein C RL4226 82 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 116253662 Common - hypothetical protein RL3922 2 None None None 116253606 Common - putative madelate racemase/muconate lactonising family protein RL3866 100 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 116250454 Common - putative transmembrane ion efflux system protein RL0682 211 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 116253736 Common - putative transmembrane ion channel protein RL3997 119 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 116251551 Common rplX 50S ribosomal protein L24 RL1785 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 116253386 Common - putative polysaccharide acetyltransferase protein RL3644 167 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 116253300 Common - putative transmembrane MFS permease protein RL3558 72 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 116252321 Common - hypothetical protein RL2575 19 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 116251241 Common - conserved hypothetical DGPF domain protein RL1475 34 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 116253765 Common - putative TetR family transcriptional regulator RL4026 87 COG1309 AcrR, Transcriptional regulator Transcription 116252714 Common cpo putative non-heme chloroperoxidase RL2967 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 116249987 Common - putative transmembrane efflux protein RL0220 61 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 116252270 Common - hypothetical protein RL2524 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 116254386 Common - hypothetical protein RL4661 5 None None None 116252593 Common - putative glyoxalase/dioxygenase RL2846 88 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 116252712 Common dusA tRNA-dihydrouridine synthase A RL2965 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 116252092 Common - putative transmembrane component of ABC transporter RL2339 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 116249950 Common mgsA methylglyoxal synthase RL0183 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 116250273 Common frk Fructokinase RL0502 114 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 116252515 Common ssuD putative alkanesulfonate monooxygenase RL2769 70 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 116250565 Common - TDP-4-oxo-6-deoxy-D-glucose transaminase RL0794 204 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 116253377 Nonpathogen - hypothetical protein RL3634 1 None None None 116252426 Common - putative transposase RL2679 31 None None None 116254283 Nonpathogen - putative exported surface protein RL4556 1 None None None 116251168 Common - putative transmembrane fatty acid desaturase RL1400 37 COG3239 DesA, Fatty acid desaturase Lipid metabolism 116251927 Common - hypothetical protein RL2169 7 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 116254162 Common - putative 3-oxoacyl-[acyl-carrier-protein] reductase RL4430 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251131 Common - putative oxidoreductase RL1363 116 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 116252534 Common - putative ATP-binding component of ABC transporter RL2787 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 116250953 Common - putative short-chain dehydrogenase/reductase RL1185 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116251977 Common rpsB 30S ribosomal protein S2 RL2221 222 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 116250627 Common - hypothetical protein RL0854 4 None None None 116249953 Common - putative transmembrane component of ABC transporter RL0186 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 116252463 Common - putative DeoR family transcriptional regulator RL2716 70 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 116252731 Nonpathogen - putative transmembrane protein RL2985 1 None None None 116251667 Nonpathogen - hypothetical protein RL1902 1 None None None 116252887 Common - putative LysR family transcriptional regulator RL3146 113 COG0583 LysR, Transcriptional regulator Transcription 116251461 Common - hypothetical protein RL1695 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 116252836 Common - hypothetical protein RL3093 9 COG5439 COG5439, Uncharacterized conserved protein Function unknown 116250406 Common - putative short-chain dehydrogenase RL0634 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 116252882 Common - putative alkanal monooxygenase alpha chain (bacterial luciferase family protein) RL3141 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 116250328 Common - hypothetical protein RL0556 7 None None None 116251091 Nonpathogen - hypothetical protein RL1323 1 None None None 116249832 Common - putative phosphoketolase RL0066 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 116251538 Common tufB2 elongation factor Tu RL1772 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 116250212 Common - putative lyase RL0443 58 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 116254465 Common - putative transmembrane protein RL4741 97 COG1981 COG1981, Predicted membrane protein Function unknown 116251765 Common - putative transposase-related protein RL2002 47 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 116251876 Common dnaE putative DNA polymerase III subunit RL2117 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 116252625 Nonpathogen - hypothetical protein RL2878 1 None None None 116251841 Common - putative transmembrane protein RL2081 2 COG3326 COG3326, Predicted membrane protein Function unknown 116252541 Common - putative transmembrane component of ABC transporter RL2794 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 116252549 Common - hypothetical protein RL2802 34 COG3911 COG3911, Predicted ATPase General function prediction only 116252250 Common - putative acetyltransferase RL2504 35 COG2153 ElaA, Predicted acyltransferase General function prediction only 116251622 Common - putative DJ-1/PfpI family protein RL1856 128 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 116250267 Common - putative GGDEF sensory box protein, pseudogene RL0496 126 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 116252398 Common fdxB putative ferredoxin, 2Fe-2S RL2652 57 COG0633 Fdx, Ferredoxin Energy production and conversion 116252383 Common recA recombinase A RL2637 232 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 116253240 Common - hypothetical protein RL3498 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 116253475 Common ureB urease subunit beta RL3734 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 116253010 Common - putative OmpA family outer membrane protein RL3267 169 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 116251104 Common - hypothetical protein RL1336 5 None None None 116250703 Nonpathogen - hypothetical protein RL0929 1 None None None 116253418 Common lspL putative UDP-glucuronate 5'-epimerase RL3677 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 116252000 Common ada putative arylesterase RL2244 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 116250672 Common - putative glutathione-regulated cation-efflux system protein RL0898 206 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 116251054 Common - putative LysR family transcriptional regulator RL1287 138 COG0583 LysR, Transcriptional regulator Transcription 116253919 Common - putative AraC family transcriptional regulator RL4182 127 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 116252719 Common - putative two component response regulator transcriptional regulatory protein RL2973 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 116252307 Common - putative transmembrane efflux/ MDR protein RL2561 143 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 116250412 Common - hypothetical protein RL0640 25 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 116251518 Common dhaL2 putative PTS-dependent dihydroxyacetone kinase,ADP-binding subunit RL1752 75 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 116253463 Common - putative periplasmic-component of ABC transporter RL3723 94 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 116253910 Common - putative transmembrane component of ABC transporter RL4173 119 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 116252967 Common - putative LysR family transcriptional regulator RL3225 171 COG0583 LysR, Transcriptional regulator Transcription 116250426 Common - hypothetical protein RL0654 49 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 116253659 Nonpathogen - hypothetical protein RL3919 1 None None None 116251880 Common - hypothetical protein RL2120 25 COG2135 COG2135, Uncharacterized conserved protein Function unknown 116252697 Common - hypothetical protein RL2950 19 None None None