Francisella tularensis subsp. holarctica OSU18, complete genome NC_008369 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 115315021 Common hemL glutamate-1-semialdehyde 2,1-aminomutase FTH_1255 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 115315211 Common mraW S-adenosyl-methyltransferase FTH_1491 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 115314014 Common - probable transglutaminase FTH_0044 88 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 115314291 Common - aspartate aminotransferase FTH_0378 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 115314567 Common glyA glycine hydroxymethyltransferase FTH_0705 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 115314425 Common - possible outer membrane protein FTH_0538 39 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 115315501 Common - hypothetical protein FTH_1837 2 None None None 115314520 Common - hypothetical protein FTH_0654 11 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 115313987 Common - probable outer membrane protein OmpH FTH_0009 5 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 115314055 Common - chloride channel protein FTH_0095 159 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 115313999 Pathogen - hypothetical protein FTH_0025 1 None None None 162139939 Common fadE acyl-CoA dehydrogenase FTH_0585 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 115314584 Common dedA1 DedA family protein FTH_0723 167 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 115314306 Common ubiE menaquinone biosynthesis methyltransferase FTH_0397 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 115314199 Common - glutamate dehydrogenase FTH_0268 168 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 115314230 Common nhaP CPA1 family monovalent cation:proton (H+) antiporter-1 FTH_0305 149 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 115315346 Common - hypothetical protein FTH_1656 84 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 115314046 Common - ferredoxin FTH_0084 155 COG1146 COG1146, Ferredoxin Energy production and conversion 115314031 Common omlA outer membrane lipoprotein FTH_0065 34 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 115314228 Pathogen - hypothetical protein FTH_0303 1 None None None 115314273 Pathogen - possible type IV pilus assembly protein FTH_0355 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 115314146 Pathogen - hypothetical protein FTH_0203 1 None None None 115315507 Common isftu1 ISFtu1 transposase FTH_1846 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314783 Common - ubiquinone biosynthesis protein FTH_0968 49 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 115314547 Common potB polyamine ABC superfamily ATP binding cassette transporter, membrane protein FTH_0682 200 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 115314824 Pathogen - hypothetical protein FTH_1019 1 None None None 115314037 Common ribH riboflavin synthase beta subunit FTH_0071 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 115314269 Common - probable 4-hydroxybenzoate synthetase FTH_0351 6 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 115315250 Common apaH diadenosine tetraphosphatase FTH_1540 105 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 115314709 Common - DNA-binding protein HU-beta FTH_0880 213 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 115314856 Common - possible transcriptional regulator FTH_1055 53 COG3655 COG3655, Predicted transcriptional regulator Transcription 115315349 Common - hemK methylase FTH_1659 217 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 115314089 Common - ABC superfamily ATP binding cassette transporter, membrane protein FTH_0138 135 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 115314463 Common fadB/acbP 3-hydroxyacyl-CoA dehydrogenase FTH_0584 163 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 115315342 Common groES co-chaperonin GroES FTH_1652 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 115315285 Pathogen - hypothetical protein FTH_1582 2 None None None 115315099 Common - hypothetical protein FTH_1360 53 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 115314738 Common - possible ArsR family arsenical resistance operon repressor FTH_0914 10 None None None 115314212 Common - hypothetical protein FTH_0285 2 None None None 115314921 Pathogen - hypothetical protein FTH_1141 1 None None None 115314316 Common engA GTP-binding protein EngA FTH_0407 222 COG1160 COG1160, Predicted GTPases General function prediction only 115314471 Common - galactosyltransferase FTH_0593 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 115314974 Common - possible transcriptional regulator FTH_1200 28 COG1846 MarR, Transcriptional regulators Transcription 115314390 Common murF UDP-N-acetylmuramyl pentapeptide synthase FTH_0490 212 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 115314243 Common - probable NCS2 family xanthine:uracil symporter-2 FTH_0319 134 COG2252 COG2252, Permeases General function prediction only 115314338 Common - hypothetical protein FTH_0435 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 115314556 Common - POT family proton (H+)-dependent oligopeptide transporter FTH_0693 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 115314759 Common hslV ATP-dependent protease peptidase subunit FTH_0942 155 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 115314735 Common ruvA crossover junction endodeoxyribonuclease FTH_0911 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 115314575 Common - choloylglycine family hydrolase FTH_0713 47 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 115315236 Common mutL DNA mismatch repair protein MutL FTH_1523 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 115314134 Common lpxD UDP-3-[O-3-hydroxymyristoyl] glucosamine N-acyltransferase FTH_0191 181 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 115314387 Common glyQ glycyl-tRNA synthetase subunit alpha FTH_0487 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 115315104 Common rplT 50S ribosomal protein L20 FTH_1366 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 115314610 Common - hypothetical protein FTH_0754 38 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 115314617 Common - hypothetical protein FTH_0763 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 115315523 Pathogen - hypothetical protein FTH_1867 1 None None None 115315075 Common - hypothetical protein FTH_1327 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 115315193 Common tdh L-threonine 3-dehydrogenase FTH_1473 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 115315015 Common bioC possible biotin synthesis protein BioC FTH_1247 11 None None None 115314380 Common pul pullulanase FTH_0480 129 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 115315155 Pathogen - possible type IV pilus assembly protein FTH_1429 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 115314675 Common secD preprotein translocase subunit SecD FTH_0837 216 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 115314596 Common isftu1 ISFtu1 transposase FTH_0736 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314457 Common - hypothetical protein FTH_0575 20 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 115315369 Common - fatty acid desaturase FTH_1679 64 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 115314237 Common lpd dihydrolipoyl dehydrogenase FTH_0312 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 115315302 Common - pantothenate kinase FTH_1606 113 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 115313994 Common pta phosphate acetyltransferase FTH_0016 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 115315107 Common thrS threonine--tRNA ligase FTH_1369 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115315030 Pathogen - hypothetical protein FTH_1266 1 COG1414 IclR, Transcriptional regulator Transcription 115314752 Common pth peptidyl-tRNA hydrolase FTH_0934 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 115314699 Common - possible HCC family HlyC/CorC transporter FTH_0869 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 115314636 Pathogen - hypothetical protein FTH_0787 1 None None None 115314690 Pathogen - hypothetical protein FTH_0854 1 None None None 115314544 Common - hypothetical protein FTH_0678 9 COG5495 COG5495, Uncharacterized conserved protein Function unknown 115315360 Common - hypothetical protein FTH_1670 8 None None None 115313982 Common dnaA DNA-directed DNA replication initiator protein FTH_0001 214 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 115315532 Common trpD anthranilate phosphoribosyltransferase FTH_1881 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 115315072 Common rpsU 30S ribosomal protein S21 FTH_1324 54 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 115315046 Pathogen - hypothetical protein FTH_1285 1 None None None 115314211 Common spoT1 GTP diphosphokinase FTH_0284 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 115314525 Pathogen - hypothetical protein FTH_0659 1 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 115315038 Common gshA glutamate--cysteine ligase FTH_1276 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 115315249 Common aroD 3-dehydroquinate dehydratase FTH_1539 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 115315000 Common rhlE ATP-dependent RNA helicase FTH_1229 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 115314508 Common - hypothetical protein FTH_0639 74 COG0730 COG0730, Predicted permeases General function prediction only 115314865 Common - hypothetical protein FTH_1074 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 115314808 Common rpsF 30S ribosomal protein S6 FTH_1000 182 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 115315096 Common - peptidylprolyl isomerase FTH_1355 141 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 115315352 Common - hypothetical protein FTH_1662 12 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 115315090 Pathogen - hypothetical protein FTH_1347 1 None None None 115314065 Pathogen - hypothetical protein FTH_0109 1 None None None 115315452 Common - MFS family major facilitator transporter FTH_1771 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314395 Common lpxH UDP-2,3-diacylglucosamine hydrolase FTH_0503 81 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 115315480 Common - isopropylmalate isomerase large subunit FTH_1814 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 115315131 Common galE UDP-glucose 4-epimerase FTH_1393 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 115315370 Common gcp O-sialoglycoprotein endopeptidase FTH_1680 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 115314438 Common proC pyrroline-5-carboxylate reductase FTH_0551 196 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 115314982 Common trkA potassium transporter peripheral membrane component FTH_1209 133 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 115315321 Pathogen - hypothetical protein FTH_1628 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 115314511 Pathogen - hypothetical protein FTH_0642 1 None None None 115315191 Common - probable chitinase FTH_1471 44 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 115314903 Pathogen - hypothetical protein FTH_1119 1 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 115314328 Common guaA1 GMP synthase (glutamine-hydrolyzing) FTH_0422 100 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 115313989 Common secB1 preprotein translocase subunit SecB FTH_0011 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 115314964 Pathogen - hypothetical protein FTH_1189 1 None None None 115315461 Common purB adenylosuccinate lyase FTH_1782 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 115315053 Common coaD pantetheine-phosphate adenylyltransferase FTH_1295 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 115314184 Common rpsN 30S ribosomal protein S14 FTH_0244 210 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 115315004 Common - oxidoreductase FTH_1234 182 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 115315267 Common wcaA glycosyl transferase, group 2 family protein FTH_1558 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 115315223 Common - hypothetical protein FTH_1503 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 115315059 Common pheA prephenate dehydratase FTH_1301 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 115315242 Common - hypothetical protein FTH_1530 130 COG0628 PerM, Predicted permease General function prediction only 115314820 Pathogen - hypothetical protein FTH_1013 1 None None None 115315010 Common - esterase FTH_1241 138 COG0657 Aes, Esterase/lipase Lipid metabolism 115314750 Pathogen - hypothetical protein FTH_0932 1 None None None 115314109 Pathogen - hypothetical protein FTH_0163 1 None None None 115315113 Common recR recombination protein RecR FTH_1375 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 115314207 Common dnaJ1 chaperone DnaJ FTH_0280 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 115315024 Pathogen - hypothetical protein FTH_1258 1 None None None 115314909 Common iglA1 intracellular growth locus A protein FTH_1129 46 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 115314342 Pathogen - hypothetical protein FTH_0439 1 None None None 115314414 Pathogen - hypothetical protein FTH_0522 1 None None None 115314946 Common - LysR family transcriptional regulator FTH_1169 116 COG0583 LysR, Transcriptional regulator Transcription 115314487 Common trxA1 thioredoxin FTH_0612 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 115314744 Common - probable NMC family nicotinamide mononucleotide uptake permease PnuC FTH_0921 59 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 115314001 Common carB carbamoyl phosphate synthase large subunit FTH_0028 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 115314749 Common - possible HCC family HlyC/CorC transporter FTH_0929 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 115314454 Common - hypothetical protein FTH_0572 24 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 115315448 Common fur2 ferric/zinc (Fe2+/Zn2) uptake regulation protein FTH_1767 195 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 115314793 Common vanY M15B family D-ala-D-ala carboxypeptidase FTH_0981 52 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 115314376 Common gcvH1 glycine-cleavage system H protein FTH_0476 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 115314123 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_0180 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115315151 Common isftu1 ISFtu1 transposase FTH_1422 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315268 Common - hypothetical protein FTH_1559 56 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 115314349 Common psd phosphatidylserine decarboxylase FTH_0447 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 115315261 Common sohB predicted inner membrane peptidase FTH_1551 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 115314605 Common uvrB excinuclease ABC subunit B FTH_0747 233 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 115314704 Common tdk thymidine kinase FTH_0875 80 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 115315305 Common valA ABC superfamily ATP binding cassette transporter, ATP-binding protein FTH_1609 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 115314474 Common wecC ECA biosynthesis protein FTH_0596 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 115315472 Common nhaD NhaD family sodium:proton (Na+:H+) antiporter FTH_1797 43 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 115314356 Common cspC cold shock protein FTH_0454 179 COG1278 CspC, Cold shock proteins Transcription 115315425 Common - MFS family major facilitator transporter FTH_1743 97 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115315142 Common rnd ribonuclease III FTH_1411 118 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 115314058 Common isftu1 ISFtu1 transposase FTH_0100 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314885 Common hipA possible transcriptional regulator FTH_1099 70 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 115314839 Common - serine-type D-Ala-D-Ala carboxypeptidase FTH_1036 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 115315411 Common - glutaredoxin-related protein FTH_1729 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 115315440 Common nuoH NADH dehydrogenase (ubiquinone) FTH_1759 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 115315061 Common - hypothetical protein FTH_1305 12 None None None 115314447 Common cfa cyclopropane-fatty-acyl-phospholipid synthase FTH_0562 125 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 115314719 Pathogen - hypothetical protein FTH_0892 1 None None None 115315489 Common lysU lysine--tRNA ligase FTH_1825 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 115314200 Common lysA1 diaminopimelate decarboxylase FTH_0271 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 115314940 Common rplM 50S ribosomal protein L13 FTH_1163 236 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 115314140 Common - hypothetical protein FTH_0197 4 None None None 115315389 Pathogen - hypothetical protein FTH_1705 1 None None None 115314491 Common - AAA family ATPase FTH_0617 195 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 115315085 Common - sugar kinase FTH_1340 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 115314801 Common cmk cytidylate kinase FTH_0992 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 115314978 Common - ABC superfamily ATP binding cassette transporter, membrane protein FTH_1205 163 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 115314025 Common - HAAAP family aromatic amino acid transporter FTH_0057 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 115315490 Pathogen - hypothetical protein FTH_1826 1 None None None 115314947 Pathogen - hypothetical protein FTH_1170 1 None None None 115315122 Common - possible HAD superfamily haloacid dehalogenase hydrolase FTH_1384 48 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 115314937 Common mglB ClpXP protease specificity-enhancing factor FTH_1160 64 COG2969 SspB, Stringent starvation protein B General function prediction only 115314275 Common lemA LemA family protein FTH_0357 127 COG1704 LemA, Uncharacterized conserved protein Function unknown 115314062 Pathogen iglD2 intracellular growth locus D protein FTH_0106 1 None None None 115314214 Pathogen - hypothetical protein FTH_0287 1 None None None 115314429 Common lpxB 1,4-alpha-glucan branching enzyme FTH_0542 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 115315066 Common recF DNA replication and repair protein RecF FTH_1315 147 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 115315394 Pathogen - hypothetical protein FTH_1712 3 None None None 115315438 Pathogen nuoJ NADH dehydrogenase (ubiquinone) FTH_1757 1 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 115314936 Common - possible SSS family solute:sodium (Na+) symporter FTH_1159 62 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 115315372 Common rpoC DNA-directed RNA polymerase FTH_1682 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 115314159 Common rpsB 30S ribosomal protein S2 FTH_0219 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 115314095 Pathogen - hypothetical protein FTH_0145 1 None None None 115315127 Common - hypothetical protein FTH_1389 5 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 115314294 Pathogen - hypothetical protein FTH_0381 1 None None None 115314930 Pathogen - hypothetical protein FTH_1153 1 None None None 115314222 Common accA acetyl-CoA carboxylase alpha subunit FTH_0295 215 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 115314336 Pathogen - hypothetical protein FTH_0431 1 None None None 115314686 Common - possible rubredoxin FTH_0848 114 COG1773 COG1773, Rubredoxin Energy production and conversion 115314702 Common miaB possible 2-methylthioadenine synthetase FTH_0872 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 115315331 Common - probable alpha/beta superfamily hydrolase FTH_1639 82 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 115315171 Common serS seryl-tRNA synthetase FTH_1445 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314518 Pathogen - hypothetical protein FTH_0652 1 None None None 115315157 Common - thiamine diphosphokinase FTH_1431 16 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 115315183 Common katG catalase FTH_1458 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 115314570 Pathogen - hypothetical protein FTH_0708 1 None None None 115314404 Common - possible organic solvent ABC superfamily ATP binding cassette transporter, binding protein FTH_0512 101 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 115315512 Common - ABC superfamily ATP binding cassette transporter, ATP-binding protein FTH_1854 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 115314254 Common tolB TolB protein FTH_0332 144 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 115314117 Common - inner membrane protein FTH_0172 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 115315218 Common - hypothetical protein FTH_1498 12 None None None 115314144 Common - hypothetical protein FTH_0201 34 None None None 115315316 Common hemK N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase FTH_1623 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 115314501 Common ppnK NAD(+) kinase FTH_0629 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 115314902 Common rpmF 50S ribosomal protein L32 FTH_1118 54 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 115314807 Pathogen - hypothetical protein FTH_0999 1 None None None 115314847 Common truA tRNA pseudouridine synthase A FTH_1044 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 115314726 Common nth DNA-(apurinic or apyrimidinic site) lyase FTH_0901 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 115314589 Common ubiH 2-octaprenyl-6-methoxyphenyl hydroxylase FTH_0728 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 115314011 Pathogen - hypothetical protein FTH_0039 1 None None None 115314577 Common serA D-3-phosphoglycerate dehydrogenase FTH_0716 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 115314863 Common msrA1 bifunctional methionine sulfoxide reductase B/A protein FTH_1069 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 115314276 Common arsR arsenic resistance operon repressor FTH_0362 74 COG0640 ArsR, Predicted transcriptional regulators Transcription 115314251 Common tolQ TolQ protein FTH_0329 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 115314631 Common - M22 family peptidase FTH_0781 176 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 115314757 Common - POT family proton (H+)-dependent oligopeptide transporter FTH_0940 73 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 115315272 Common pckA phosphoenolpyruvate carboxykinase FTH_1563 96 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 115314591 Pathogen - hypothetical protein FTH_0730 1 None None None 115314136 Common pdxY pyridoxal kinase FTH_0193 81 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 115314087 Pathogen - hypothetical protein FTH_0136 1 None None None 115315340 Common isftu1 ISFtu1 transposase FTH_1650 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314622 Common - hypothetical protein FTH_0768 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 115314837 Common lipB lipoate--protein ligase B FTH_1034 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 115315259 Common yhbY RNA-binding protein FTH_1549 101 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 115314600 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA FTH_0741 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 115314858 Pathogen - hypothetical protein FTH_1060 1 None None None 115314769 Common prmA ribosomal protein L11 methyltransferase FTH_0953 178 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 115314263 Common - BASS family bile acid:sodium (Na+) symporter FTH_0342 62 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 115314424 Common - outer membrane protein/protective antigen FTH_0537 159 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 115314733 Common ruvC crossover junction endodeoxyribonuclease FTH_0909 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 115314240 Common arsC1 arsenate reductase (glutaredoxin) FTH_0316 36 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 115314976 Common trxA2 thioredoxin FTH_1202 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 115314843 Pathogen - hypothetical protein FTH_1040 1 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 115314968 Common - hypothetical protein FTH_1193 122 COG1678 COG1678, Putative transcriptional regulator Transcription 115314288 Common - probable sterol desaturase FTH_0374 77 COG3000 ERG3, Sterol desaturase Lipid metabolism 115314762 Common tyrS tyrosyl-tRNA synthetase FTH_0945 242 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314980 Common - cysteine desulfurase activator complex subunit SufB FTH_1207 183 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 115314826 Common - peptidylprolyl isomerase FTH_1021 77 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 115315070 Common - CDF family cation diffusion facilitator FTH_1321 194 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 115315118 Common - MFS family major facilitator transporter FTH_1380 151 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314281 Common radA DNA repair protein RadA FTH_0367 225 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 115314564 Common rluD pseudouridylate synthase FTH_0701 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 115314197 Pathogen - hypothetical protein FTH_0261 1 None None None 115314958 Common - probable chromosome partitioning ATPase FTH_1182 232 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 115314323 Pathogen lpnB conserved hypothetical lipoprotein FTH_0417 1 None None None 115315083 Pathogen - hypothetical protein FTH_1336 1 None None None 115314522 Common - SufE family Fe-S protein FTH_0656 95 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 115314152 Common nfnB dihydropteridine reductase FTH_0210 55 COG0778 NfnB, Nitroreductase Energy production and conversion 115314157 Common - hypothetical protein FTH_0217 15 COG4874 COG4874, Uncharacterized protein conserved in bacteria containing a pentein-type domain Function unknown 115314397 Common murC UDP-N-acetylmuramate--alanine ligase FTH_0505 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 115314641 Common - type IV pilus assembly protein FTH_0792 2 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 115314629 Common - GTP-binding protein FTH_0779 96 COG1161 COG1161, Predicted GTPases General function prediction only 115314233 Common coaE dephospho-CoA kinase FTH_0308 199 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 115315279 Pathogen - hypothetical protein FTH_1574 1 None None None 115314048 Common purT phosphoribosylglycinamide formyltransferase 2 FTH_0087 212 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 115314496 Common tatD magnesium (Mg2+)-dependent deoxyribonuclease FTH_0623 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 115314634 Common era GTP-binding protein Era FTH_0784 233 COG1159 Era, GTPase General function prediction only 115315344 Common - hypothetical protein FTH_1654 37 COG4125 COG4125, Predicted membrane protein Function unknown 115314347 Pathogen - hypothetical protein FTH_0445 1 None None None 115314113 Pathogen - hypothetical protein FTH_0168 2 None None None 115314006 Common - hypothetical protein FTH_0033 4 None None None 115314292 Common - CDF family cation diffusion facilitator FTH_0379 135 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 115313985 Common - possible CPA1 family monovalent cation:proton (H+) antiporter-1 FTH_0005 59 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 115314460 Common - MFS family major facilitator transporter FTH_0581 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314653 Pathogen - hypothetical protein FTH_0806 1 None None None 115314774 Pathogen - hypothetical protein FTH_0959 1 None None None 115314506 Common - possible rhodanese sulfurtransferase family protein FTH_0636 39 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 115315002 Common - hypothetical protein FTH_1231 42 COG1434 COG1434, Uncharacterized conserved protein Function unknown 115314163 Common uppS di-trans,poly-cis-decaprenylcistransferase FTH_0223 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 115314036 Common def peptide deformylase FTH_0070 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 115314875 Common - hypothetical protein FTH_1088 44 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 115315094 Common gmk guanylate kinase FTH_1353 212 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 115314660 Common pilC type IV pilus assembly protein FTH_0817 150 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 115315006 Common trpE1 anthranilate synthase FTH_1237 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 115314893 Common - hypothetical protein FTH_1108 115 COG2855 COG2855, Predicted membrane protein Function unknown 115315195 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FTH_1475 189 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 115315323 Pathogen - hypothetical protein FTH_1630 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 115314598 Pathogen - hypothetical protein FTH_0739 1 None None None 115314513 Common - probable aminohydrolase FTH_0645 179 COG0388 COG0388, Predicted amidohydrolase General function prediction only 115315047 Common isftu1 ISFtu1 transposase FTH_1286 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314914 Pathogen pdpC1 conserved protein PdpC FTH_1134 1 None None None 115314182 Common rplX 50S ribosomal protein L24 FTH_0242 209 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 115314905 Common gapA glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) FTH_1121 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 115315017 Common birA1 biotin--[acetyl-CoA-carboxylase] ligase FTH_1249 205 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 115314382 Common pgm phosphoglucomutase FTH_0482 212 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 115315339 Pathogen - hypothetical protein FTH_1648 1 None None None 115314221 Common mutS DNA mismatch repair protein FTH_0294 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 115315468 Common tolC outer membrane protein tolC precursor FTH_1793 117 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 115315525 Common pepN membrane alanyl aminopeptidase FTH_1873 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 115314612 Common xseA exodeoxyribonuclease VII large subunit FTH_0757 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 115314587 Common - 5-formyltetrahydrofolate cyclo-ligase FTH_0726 64 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 115314304 Pathogen - hypothetical protein FTH_0395 1 None None None 115314989 Common ffh Sec family Type II general secretory pathway signal recognition particle protein Ffh FTH_1216 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 115314656 Pathogen - hypothetical protein FTH_0810 1 None None None 115314619 Common - possible glycine/D-amino acid oxidase FTH_0765 66 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 115314772 Common - hypothetical protein FTH_0956 44 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 115315534 Common trpE2 anthranilate synthase component I FTH_1883 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 115315079 Common - hypothetical protein FTH_1332 41 COG1289 COG1289, Predicted membrane protein Function unknown 115315421 Pathogen - hypothetical protein FTH_1739 1 None None None 115314542 Common panC pantoate--beta-alanine ligase FTH_0676 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 115315297 Common tmk dTMP kinase FTH_1601 234 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 115314692 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase FTH_0861 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 115314480 Common - hypothetical protein FTH_0602 40 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 115314080 Common - possible lipopolysaccharide biosynthesis protein FTH_0129 8 None None None 115315032 Pathogen - hypothetical protein FTH_1269 1 None None None 115315362 Common - oxidoreductase FTH_1672 50 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 115314527 Common - hypothetical protein FTH_0661 2 None None None 115315109 Pathogen - hypothetical protein FTH_1371 1 None None None 115315052 Common fdx ferredoxin FTH_1294 111 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 115315458 Common gatA aspartyl/glutamyl-tRNA (Asn/Gln) amidotransferase subunit A FTH_1777 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 115314311 Common - amidophosphoribosyltransferase FTH_0402 126 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 115315042 Common folC dihydrofolate synthase FTH_1280 215 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 115314125 Pathogen - hypothetical protein FTH_0182 1 None None None 115315423 Common rluC pseudouridylate synthase FTH_1741 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 115314354 Common - acetyltransferase FTH_0452 9 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 115315307 Pathogen dsbB disulfide bond formation protein FTH_1611 1 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 115315230 Common aspG asparaginase FTH_1511 82 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 115315019 Common adc acetoacetate decarboxylase FTH_1252 18 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 115314700 Common - hypothetical protein FTH_0870 167 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 115315263 Common dsrC dissimilatory sulfite reductase subunit gamma FTH_1553 59 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 115314476 Pathogen wzy O-antigen polymerase FTH_0598 1 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 115315392 Common - hypothetical protein FTH_1710 21 COG2246 COG2246, Predicted membrane protein Function unknown 115315406 Common sdhC succinate dehydrogenase FTH_1724 56 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 115314790 Pathogen - hypothetical protein FTH_0977 1 None None None 115315237 Pathogen - hypothetical protein FTH_1525 1 None None None 115314553 Common - MFS family major facilitator transporter FTH_0690 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314788 Common ahpC probable peroxiredoxin FTH_0974 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 115314162 Common prfH protein-synthesizing GTPase FTH_0222 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 115314717 Common engB GTPase EngB FTH_0889 178 COG0218 COG0218, Predicted GTPase General function prediction only 115314459 Common - hypothetical protein FTH_0580 8 None None None 115315134 Common kdsD arabinose-5-phosphate isomerase FTH_1396 186 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 115315442 Common nuoF NADH dehydrogenase (ubiquinone) FTH_1761 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 115315138 Common - possible Rossmann fold nucleotide-binding protein FTH_1404 133 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 115313990 Common recA recombination protein RecA FTH_0012 240 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 115314142 Common - hypothetical protein FTH_0199 64 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 115314805 Pathogen - hypothetical protein FTH_0996 2 None None None 115315050 Common - hypothetical protein FTH_1290 3 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 115315057 Common sdaA/tdcB L-serine ammonia-lyase FTH_1299 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 115314003 Pathogen - acid phosphatase FTH_0030 2 None None None 115314239 Common mutT MutT/nudix family protein FTH_0315 48 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 115314368 Common - hypothetical protein FTH_0467 2 COG4325 COG4325, Predicted membrane protein Function unknown 115315140 Pathogen - hypothetical protein FTH_1409 2 None None None 115314008 Common - hypothetical protein FTH_0036 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 115315332 Common - (lysine) APC family amino acid-polyamine-organocation transporter FTH_1640 163 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 115315374 Pathogen - hypothetical protein FTH_1684 1 None None None 115315403 Common sdhB succinate dehydrogenase iron-sulfur subunit FTH_1721 200 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 115315387 Common - possible nucleoside-diphosphate sugar epimerase FTH_1702 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 115314747 Common prsA ribose-phosphate diphosphokinase FTH_0927 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 115314093 Common lolB outer membrane lipoprotein FTH_0143 51 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 115314961 Common leuS leucyl-tRNA synthetase FTH_1186 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314049 Common - chitinase FTH_0088 10 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 115315273 Common glnS glutaminyl-tRNA synthetase FTH_1564 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 115314075 Common ilvE branched-chain-amino-acid transaminase FTH_0122 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 115314742 Common - DNA methylpurine-DNA glycosylase FTH_0919 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 115315253 Common ostA organic solvent tolerance protein FTH_1543 112 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 115315482 Pathogen - hypothetical protein FTH_1816 1 None None None 115315514 Pathogen - outer membrane lipoprotein FTH_1857 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 115315479 Common leuD 3-isopropylmalate dehydratase small subunit FTH_1813 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 115315204 Common udk uridine kinase FTH_1484 89 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 115314724 Pathogen - hypothetical protein FTH_0899 1 None None None 115314378 Common gcvP2 glycine dehydrogenase subunit 2 FTH_0478 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 115315026 Common - possible fatty acid hydroxylase FTH_1260 8 COG3000 ERG3, Sterol desaturase Lipid metabolism 115314321 Pathogen lpnA 17 kDa lipoprotein TUL4 precursor FTH_0414 1 None None None 115315209 Common ftsI peptidoglycan glycosyltransferase FTH_1489 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 115314662 Common glpQ glycerophosphodiester phosphodiesterase FTH_0819 124 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 115314845 Common - fumarylacetoacetate hydrolase FTH_1042 161 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 115315491 Common prfB peptide chain release factor B FTH_1827 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 115315221 Pathogen - hypothetical protein FTH_1501 1 None None None 115315173 Common - MOP/MATE superfamily multidrug/oligosaccharidyl-lipid/polysaccharide flippase FTH_1447 19 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 115314445 Common - hypothetical protein FTH_0560 36 None None None 115314707 Common clpX ATP-dependent protease ATP-binding subunit FTH_0878 218 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 115314442 Common truB pseudouridylate synthase FTH_0556 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 115314814 Common rluB pseudouridylate synthase FTH_1006 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 115314851 Common - possible lipase FTH_1049 113 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 115314878 Common - rhodanese sulfurtransferase FTH_1091 111 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 115314572 Common - glycosyltransferase FTH_0710 29 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 115315483 Pathogen - hypothetical protein FTH_1818 1 None None None 115314252 Common tolR TolR protein FTH_0330 140 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 115314607 Common murI glutamate racemase FTH_0749 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 115314111 Common - tetrapyrrole methyltransferase FTH_0165 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 115314092 Common - carbonate dehydratase FTH_0142 186 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 115314224 Pathogen - hypothetical protein FTH_0297 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 115314147 Common holC DNA-directed DNA polymerase FTH_0204 2 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 115315244 Common birA2 biotin--[acetyl-CoA-carboxylase] ligase FTH_1532 166 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 115314027 Common - possible alanine racemase FTH_0059 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 115314673 Pathogen - hypothetical protein FTH_0835 1 None None None 115314722 Common mfd transcription-repair coupling factor TRCF FTH_0897 228 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 115314176 Common rplV 50S ribosomal protein L22 FTH_0236 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 115314684 Pathogen - hypothetical protein FTH_0846 1 None None None 115314340 Common metG methionyl-tRNA synthetase FTH_0437 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314911 Pathogen iglC1 intracellular growth locus C protein FTH_1131 1 None None None 115314494 Common - probable bacterioferritin FTH_0620 22 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 115314944 Common dnaK chaperone DnaK FTH_1167 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 115315115 Common - hypothetical protein FTH_1377 6 None None None 115315315 Common cysS cysteine--tRNA ligase FTH_1622 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115315413 Common atpC H(+)-transporting two-sector ATPase FTH_1731 140 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 115314318 Common - hypothetical protein FTH_0411 67 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 115314169 Common fusA elongation factor G FTH_0229 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 115315432 Common isftu1 ISFtu1 transposase FTH_1751 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314456 Common - hypothetical protein FTH_0574 10 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 115314099 Common - PiT family inorganic phosphate transporter FTH_0150 172 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 115314217 Common - HAAAP family hydroxy/aromatic amino acid permease FTH_0290 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 115314932 Common - possible sigma 54 modulation protein/SE30A ribosomal protein FTH_1155 144 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 115314991 Common isftu1 ISFtu1 transposase FTH_1219 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314582 Pathogen - hypothetical protein FTH_0721 1 None None None 115314939 Common rpsI 30S ribosomal protein S9 FTH_1162 228 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 115314103 Common - hypothetical protein FTH_0155 95 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 115315129 Common - ABC superfamily ATP binding cassette transporter, ABC/membrane protein FTH_1391 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 115314951 Common - phenylalanine--tRNA ligase FTH_1174 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 115315101 Common - hypothetical protein FTH_1362 98 COG2835 COG2835, Uncharacterized conserved protein Function unknown 115314693 Common - hypothetical protein FTH_0862 178 COG1496 COG1496, Uncharacterized conserved protein Function unknown 115314874 Common - nicotinamidase FTH_1087 5 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 115314150 Common - hypothetical protein FTH_0207 6 None None None 115314614 Pathogen - hypothetical protein FTH_0760 1 None None None 115314760 Pathogen - hypothetical protein FTH_0943 1 None None None 115315419 Common atpE H(+)-transporting two-sector ATPase FTH_1737 68 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 115314408 Common minD septum site-determining protein MinD FTH_0516 144 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 115315527 Common trpC/trpF bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase FTH_1875 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 115314767 Common - probable FAD/FMN-dehydrogenase FTH_0950 192 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 115315076 Common - hypothetical protein FTH_1328 81 COG0657 Aes, Esterase/lipase Lipid metabolism 115314516 Pathogen - hypothetical protein FTH_0648 1 None None None 115314482 Common - glycosyltransferase FTH_0604 163 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 115314381 Common glgB glycogen branching enzyme FTH_0481 146 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 115315159 Common pepA leucyl aminopeptidase FTH_1433 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 115314898 Common fabG 3-oxoacyl-[acyl-carrier-protein] reductase FTH_1114 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 115315428 Common infB translation initiation factor IF-2 FTH_1746 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 115314908 Common fba fructose-1,6-bisphosphate aldolase FTH_1124 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 115314298 Common purM phosphoribosylaminoimidazole synthetase FTH_0387 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 115315039 Common mviN MVF family mouse virulence factor transporter MviN FTH_1277 187 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 115315337 Common trkH Trk family K+ transporter, membrane protein FTH_1645 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 115315433 Common - hypothetical protein FTH_1752 3 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 115315382 Pathogen - hypothetical protein FTH_1694 1 None None None 115314138 Common moxR MoxR family ATPase FTH_0195 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 115314204 Common - probable pyruvate/2-oxoglutarate dehydrogenase FTH_0276 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 115314174 Common rplB 50S ribosomal protein L2 FTH_0234 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 115314411 Common rpmB 50S ribosomal protein L28 FTH_0519 160 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 115314529 Pathogen - hypothetical protein FTH_0663 1 None None None 115314191 Common secY preprotein translocase subunit SecY FTH_0251 230 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 115314695 Common - probable endonuclease FTH_0864 44 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 115314655 Pathogen - hypothetical protein FTH_0808 1 None None None 115315214 Common isftu1 ISFtu1 transposase FTH_1494 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314817 Pathogen - hypothetical protein FTH_1010 1 None None None 115315007 Common fadD2 long-chain-fatty-acid--CoA ligase FTH_1238 202 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 115315520 Common - putative ABC transporter ATP-binding protein FTH_1864 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 115314069 Common - hypothetical protein FTH_0113 4 None None None 115314490 Pathogen - hypothetical protein FTH_0616 1 None None None 115315364 Common rplS 50S ribosomal protein L19 FTH_1674 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 115315143 Common - MFS family major facilitator transporter FTH_1412 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314141 Common - hypothetical protein FTH_0198 86 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 115315240 Common potF putrescine ABC superfamily ATP binding cassette transporter, binding protein FTH_1528 123 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 115315322 Pathogen - hypothetical protein FTH_1629 1 None None None 115314895 Common - hypothetical protein FTH_1111 31 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 115315325 Pathogen - hypothetical protein FTH_1632 1 None None None 115315197 Common eno phosphopyruvate hydratase FTH_1477 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 115314554 Common - AraC family transcriptional regulator FTH_0691 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 115314309 Common hitA HIT family histidine triad protein FTH_0400 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 115314168 Common rpsG 30S ribosomal protein S7 FTH_0228 245 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 115315147 Common secA preprotein translocase subunit SecA FTH_1418 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 115315375 Common rplL 50S ribosomal protein L7/L12 FTH_1685 210 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 115315254 Common argS arginyl-tRNA synthetase FTH_1544 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115315516 Common rbn BN family tRNA processing ribonuclease FTH_1859 83 COG1295 Rbn, Predicted membrane protein Function unknown 115314249 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase FTH_0327 149 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 115314585 Common dedA2 DedA family protein FTH_0724 150 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 115314366 Pathogen - hypothetical protein FTH_0465 1 None None None 115315466 Common purF amidophosphoribosyltransferase FTH_1790 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 115314770 Common - probable tRNA-dihydrouridine synthase FTH_0954 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 115314084 Pathogen - CrcB family protein FTH_0133 1 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 115314196 Common rplQ 50S ribosomal protein L17 FTH_0257 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 115314782 Pathogen - hypothetical protein FTH_0967 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 115314959 Common dcd deoxycytidine triphosphate deaminase FTH_1183 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 115314497 Common - hypothetical protein FTH_0624 166 COG0730 COG0730, Predicted permeases General function prediction only 115313995 Common isftu1 ISFtu1 transposase FTH_0018 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314161 Common pyrH uridylate kinase FTH_0221 242 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 115315292 Common - MFS family major facilitator transporter FTH_1591 83 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314283 Common - possible DedA family protein FTH_0369 51 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 115315119 Common ans asparaginase FTH_1381 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 115315274 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_1567 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 115314646 Pathogen - hypothetical protein FTH_0797 1 None None None 115314566 Common - FAD-binding protein FTH_0703 40 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 115314822 Pathogen - hypothetical protein FTH_1017 1 None None None 115314642 Common pilQ type IV pilus assembly protein FTH_0793 140 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 115315456 Pathogen - hypothetical protein FTH_1775 1 None None None 115314063 Pathogen - hypothetical protein FTH_0107 1 None None None 115314026 Common gidB glucose-inhibited cell division protein FTH_0058 137 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 115314633 Common aat aspartate transaminase FTH_0783 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 115314840 Common ppa inorganic diphosphatase FTH_1037 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 115314776 Common - possible transcriptional regulator FTH_0961 97 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 115315232 Common araJ MFS family major facilitator transporter FTH_1515 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314627 Common isftu1 ISFtu1 transposase FTH_0777 52 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314787 Common - possible phosphatase FTH_0973 102 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 115314593 Common - HAD superfamily haloacid dehalogenase hydrolase FTH_0732 107 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 115314009 Pathogen - hypothetical protein FTH_0037 1 COG1289 COG1289, Predicted membrane protein Function unknown 115314052 Common trpA tryptophan synthase subunit alpha FTH_0092 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 115314278 Pathogen - hypothetical protein FTH_0364 1 None None None 115314435 Common ispA geranyltranstransferase FTH_0548 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 115314085 Pathogen - hypothetical protein FTH_0134 1 None None None 115314829 Common - hypothetical protein FTH_1024 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 115314620 Common vacJ lipoprotein VacJ FTH_0766 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 115314734 Common - possible MFS family major facilitator transporter FTH_0910 126 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115315123 Common - glycosyltransferase FTH_1385 168 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 115314091 Common - CPA1 family sodium:proton (Na+:H+) antiporter-1 FTH_0141 104 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 115314970 Common - hypothetical protein FTH_1196 13 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 115315359 Common - hypothetical protein FTH_1669 3 None None None 115314234 Common - hypothetical protein FTH_0309 87 COG1565 COG1565, Uncharacterized conserved protein Function unknown 115314580 Common cafA1 ribonuclease E FTH_0719 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 115314658 Pathogen - hypothetical protein FTH_0814 1 None None None 115315162 Common - M16 family peptidase FTH_1436 199 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 115314074 Common - formate dehydrogenase FTH_0119 208 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 115314216 Common xerC integrase/recombinase XerC FTH_0289 230 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 115314755 Common pulO prepilin peptidase FTH_0937 126 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 115314130 Common cyoB cytochrome o ubiquinol oxidase subunit I FTH_0187 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 115315239 Pathogen - hypothetical protein FTH_1527 1 None None None 115315289 Common glpK glycerol kinase FTH_1588 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 115315182 Common dgt dGTPase FTH_1457 162 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 115314925 Common - hypothetical protein FTH_1146 9 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 115315510 Common hpt hypoxanthine phosphoribosyltransferase FTH_1851 147 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 115314731 Common - isoprenoid biosynthesis protein with amidotransferase-like domain FTH_0907 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 115314466 Common arsC2 arsenate reductase (glutaredoxin) FTH_0587 113 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 115314644 Common aroB 3-dehydroquinate synthase FTH_0795 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 115315089 Pathogen - hypothetical protein FTH_1346 1 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 115315064 Common glyS glycine--tRNA ligase FTH_1313 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 115314679 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase FTH_0841 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 115314531 Pathogen - hypothetical protein FTH_0665 2 None None None 115315422 Common - MFS family major facilitator transporter FTH_1740 91 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115314324 Common - type IV pilus glycosylation protein FTH_0418 2 None None None 115315291 Pathogen - hypothetical protein FTH_1590 1 None None None 115314842 Pathogen - hypothetical protein FTH_1039 1 None None None 115315496 Common ftsQ cell division protein FtsQ FTH_1832 48 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 115314227 Pathogen - hypothetical protein FTH_0300 1 None None None 115314179 Common rpmC 50S ribosomal protein L29 FTH_0239 85 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 115314608 Common - MFS family major facilitator transporter FTH_0750 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314682 Common ansA asparaginase FTH_0844 134 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 115314960 Common - hypothetical protein FTH_1185 5 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 115314953 Common - probable GTP-binding protein FTH_1176 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 115314869 Common alaS alanine--tRNA ligase FTH_1079 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314996 Common - hypothetical protein FTH_1224 2 None None None 115314333 Common ileS isoleucyl-tRNA synthetase FTH_0428 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314721 Common ilvC ketol-acid reductoisomerase FTH_0896 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 115314028 Pathogen - hypothetical protein FTH_0060 1 COG1289 COG1289, Predicted membrane protein Function unknown 115314927 Common cysK cystathionine beta-synthase FTH_1148 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 115315187 Common ugpQ glycerophosphodiester phosphodiesterase FTH_1463 134 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 115315477 Common kdpC potassium-transporting ATPase FTH_1806 93 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 115314444 Common - oxidoreductase FTH_0559 218 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 115314988 Pathogen - hypothetical protein FTH_1215 1 None None None 115315208 Common rpsO 30S ribosomal protein S15 FTH_1488 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 115315398 Common tpiA triose-phosphate isomerase FTH_1716 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 115315081 Common isftu1 ISFtu1 transposase FTH_1334 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315377 Common rplA 50S ribosomal protein L1 FTH_1687 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 115314034 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase FTH_0068 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 115315280 Common isftu1 ISFtu1 transposase FTH_1575 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314670 Common - hypothetical protein FTH_0828 170 COG0344 COG0344, Predicted membrane protein Function unknown 115314250 Pathogen - hypothetical protein FTH_0328 1 None None None 115314667 Common - rhodanese domain protein FTH_0824 147 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 115315357 Common - PAP2 family protein FTH_1667 17 None None None 115314259 Common isftu1 ISFtu1 transposase FTH_0337 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314042 Common nhaA NhaA family sodium:proton (Na+:H) antiporter FTH_0080 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 115315110 Common gcvH2 glycine cleavage system protein H FTH_1372 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 115315117 Common - probable capsule biosynthesis protein FTH_1379 16 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 115314880 Pathogen - hypothetical protein FTH_1093 1 None None None 115315310 Common - MFS family major facilitator transporter FTH_1614 61 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115315444 Common nuoD NADH dehydrogenase subunit D FTH_1763 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 115314715 Common hflC membrane protease subunit HflC FTH_0887 212 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 115314785 Common isftu1 ISFtu1 transposase FTH_0971 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314524 Pathogen - hypothetical protein FTH_0658 1 None None None 115314019 Common dtd D-tyrosyl-tRNA deacylase FTH_0049 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 115315485 Common holA DNA-directed DNA polymerase FTH_1820 70 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 115315313 Common isftu1 ISFtu1 transposase FTH_1620 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314418 Common - possible exci/endonuclease FTH_0529 39 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 115314913 Pathogen - hypothetical protein FTH_1133 1 None None None 115314351 Common - nicotinamide-nucleotide adenylyltransferase FTH_0449 94 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 115314420 Common ung uracil-DNA glycosylase FTH_0532 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 115315056 Common csdB selenocysteine lyase FTH_1298 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 115315334 Common ftsK cell division protein FTH_1642 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 115315227 Pathogen - hypothetical protein FTH_1507 1 None None None 115314552 Common - probable multidrug resistance efflux pump FTH_0689 159 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 115314118 Common - acyltransferase FTH_0173 103 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 115315467 Common - possible phosphopantetheinyl transferase FTH_1792 46 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 115315409 Pathogen - hypothetical protein FTH_1727 1 None None None 115315202 Pathogen - hypothetical protein FTH_1482 1 None None None 115314345 Pathogen - hypothetical protein FTH_0443 1 None None None 115314394 Common speE spermidine synthase FTH_0498 117 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 115315245 Common poxA lysine--tRNA ligase FTH_1533 205 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 115314889 Common isftu1 ISFtu1 transposase FTH_1103 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315408 Common ampG MFS family major facilitator transporter FTH_1726 112 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115315264 Common - hypothetical protein FTH_1554 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 115314818 Pathogen - hypothetical protein FTH_1011 1 None None None 115314835 Common ndh NADH dehydrogenase FTH_1030 163 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 115315493 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase FTH_1829 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 115314265 Common - hypothetical protein FTH_0347 6 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 115314421 Pathogen - hypothetical protein FTH_0534 1 None None None 115315095 Common - ATP-dependent RNA helicase FTH_1354 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 115314127 Common cydA cytochrome d ubiquinol oxidase subunit I FTH_0184 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 115315136 Common - hypothetical protein FTH_1400 2 None None None 115314477 Common - glycosyltransferase FTH_0599 91 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 115314853 Common - short chain dehydrogenase FTH_1051 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 115314876 Common uvrD1 ATP-dependent DNA helicase FTH_1089 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 115315165 Common - hypothetical protein FTH_1439 126 COG2860 COG2860, Predicted membrane protein Function unknown 115315178 Common dctA DAACS family dicarboxylate/amino acid:sodium (Na+) or proton (H+) symporter FTH_1452 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 115314114 Common rpmH 50S ribosomal protein L34 FTH_0169 197 None None None 115314271 Pathogen - hypothetical protein FTH_0353 1 None None None 115315145 Common rpmA 50S ribosomal protein L27 FTH_1414 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 115315009 Common folK/folP 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase FTH_1240 213 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 115315436 Common nuoL NADH dehydrogenase (ubiquinone) FTH_1755 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 115314778 Common - bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta FTH_0963 155 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 115315350 Common prfA peptide chain release factor 1 FTH_1660 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 115315190 Common upp uracil phosphoribosyltransferase FTH_1470 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 115314012 Common lysR LysR family transcriptional regulator FTH_0040 164 COG0583 LysR, Transcriptional regulator Transcription 115315149 Pathogen - hypothetical protein FTH_1420 1 None None None 115315464 Common - probable galactose mutarotase FTH_1786 41 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 115315327 Pathogen - hypothetical protein FTH_1634 1 None None None 115314218 Common - hypothetical protein FTH_0291 30 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 115314300 Common purN phosphoribosylglycinamide formyltransferase FTH_0389 225 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 115314186 Common rplF 50S ribosomal protein L6 FTH_0246 237 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 115314811 Common dnaB replicative DNA helicase FTH_1003 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 115314326 Common parA chmomosome partition protein A FTH_0420 172 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 115314509 Common - probable proline hydroxylase FTH_0640 30 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 115315366 Common rimM 16S rRNA processing protein RimM FTH_1676 136 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 115315036 Common poxF phenol 2-monooxygenase FTH_1274 155 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 115314966 Pathogen - hypothetical protein FTH_1191 1 None None None 115314188 Common rpsE 30S ribosomal protein S5 FTH_0248 216 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 115314385 Common glgP phosphorylase FTH_0485 146 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 115314484 Common manC mannose-1-phosphate guanylyltransferase (GDP) FTH_0609 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 115314369 Common dnaE DNA-directed DNA polymerase FTH_0469 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 115315529 Common - hypothetical protein FTH_1878 3 None None None 115314713 Common hflX GTP-binding protein HflX FTH_0884 224 COG2262 HflX, GTPases General function prediction only 115314448 Common - hypothetical protein FTH_0563 2 COG3496 COG3496, Uncharacterized conserved protein Function unknown 115314383 Common glgC glucose-1-phosphate adenylyltransferase FTH_0483 176 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 115315160 Common - hypothetical protein FTH_1434 44 COG0795 COG0795, Predicted permeases General function prediction only 115314427 Common fabZ 3-hydroxymyristoyl-[acyl-carrier protein] dehydratase FTH_0540 185 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 115315402 Common kgd alpha-ketoglutarate decarboxylase FTH_1720 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 115314697 Pathogen - hypothetical protein FTH_0866 2 None None None 115313984 Common isftu1 ISFtu1 transposase FTH_0004 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314677 Pathogen - hypothetical protein FTH_0839 1 None None None 115314504 Pathogen - hypothetical protein FTH_0632 1 None None None 115315044 Common ndk nucleoside-diphosphate kinase FTH_1282 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 115314172 Common rplD 50S ribosomal protein L4 FTH_0232 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 115314616 Common smpB SsrA-binding protein FTH_0762 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 115315396 Common - probable LysR family transcriptional regulator FTH_1714 23 COG0583 LysR, Transcriptional regulator Transcription 115314468 Pathogen - hypothetical protein FTH_0589 1 None None None 115314573 Common - hypothetical protein FTH_0711 2 None None None 115314923 Pathogen pdpB1 hypothetical protein FTH_1143 1 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 115314625 Pathogen - hypothetical protein FTH_0772 1 None None None 115314245 Common - possible OmpA family protein FTH_0323 89 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 115314296 Common lpxE lipid A 1-phosphatase FTH_0385 44 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 115315092 Common nadC nicotinate-nucleotide diphosphorylase (carboxylating) FTH_1351 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 115314044 Common - acyltransferase FTH_0082 158 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 115314132 Common cyoD cytochrome o ubiquinol oxidase subunit IV FTH_0189 17 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 115314867 Pathogen - hypothetical protein FTH_1076 1 None None None 115314669 Common metN D-methionine ABC superfamily ATP binding cassette transporter, ABC protein FTH_0827 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 115315498 Common - probable cytosine/adenosine deaminase FTH_1834 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 115314068 Pathogen - hypothetical protein FTH_0112 1 None None None 115314766 Pathogen - possible pyruvate decarboxylase FTH_0949 1 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 115314972 Common - APC family amino acid-polyamine-organocation transporter FTH_1198 94 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 115314984 Pathogen - hypothetical protein FTH_1211 1 None None None 115314535 Common - hypothetical protein FTH_0669 3 COG4129 COG4129, Predicted membrane protein Function unknown 115314313 Pathogen - hypothetical protein FTH_0404 1 None None None 115314371 Pathogen - hypothetical protein FTH_0471 1 None None None 115314753 Common penP beta-lactamase FTH_0935 52 COG2367 PenP, Beta-lactamase class A Defense mechanisms 115315415 Common atpG F0F1 ATP synthase subunit gamma FTH_1733 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 115314247 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase FTH_0325 183 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 115314364 Common - possible neuraminidase FTH_0462 23 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 115314156 Common - APC family amino acid-polyamine-organocation transporter FTH_0216 109 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 115314796 Common - hypothetical protein FTH_0987 94 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 115314568 Common - hypothetical protein FTH_0706 56 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 115314285 Pathogen - hypothetical protein FTH_0371 1 None None None 115314558 Common - hypothetical protein FTH_0695 10 COG2733 COG2733, Predicted membrane protein Function unknown 115314053 Common trpB tryptophan synthase subunit beta FTH_0093 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 115315150 Common deoD purine-nucleoside phosphorylase FTH_1421 61 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 115314194 Common rpsD 30S ribosomal protein S4 FTH_0255 220 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 115314071 Pathogen - hypothetical protein FTH_0116 1 None None None 115314560 Common - probable ABC superfamily ATP binding cassette transporter, ABC/membrane protein FTH_0697 62 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 115313997 Common - MFS family major facilitator transporter FTH_0021 133 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115315276 Common - hypothetical protein FTH_1569 7 COG1289 COG1289, Predicted membrane protein Function unknown 115314780 Common nrdA ribonucleotide-diphosphate reductase subunit alpha FTH_0965 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 115314082 Common - carboxylesterase/phospholipase family protein FTH_0131 88 COG0400 COG0400, Predicted esterase General function prediction only 115315294 Common ftsY signal recognition particle receptor FtsY FTH_1598 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 115314680 Pathogen - hypothetical protein FTH_0842 1 None None None 115315508 Common purH phosphoribosylaminoimidazolecarboxamide formyltransferase FTH_1849 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 115314021 Pathogen - hypothetical protein FTH_0053 1 None None None 115314689 Common - MFS family major facilitator transporter FTH_0853 168 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115314331 Pathogen - hypothetical protein FTH_0426 1 None None None 115315503 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_1842 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 115315518 Common priA primosomal protein N' FTH_1861 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 115314492 Common rpoA2 DNA-directed RNA polymerase subunit alpha FTH_0618 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 115314638 Pathogen - hypothetical protein FTH_0789 1 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 115314545 Common ligN DNA ligase (NAD(+)) FTH_0679 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 115314711 Common miaA tRNA isopentenyltransferase FTH_0882 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 115314485 Common manB phosphomannomutase FTH_0610 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 115315020 Common - beta-N-acetylhexosaminidase FTH_1254 175 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 115314833 Common dnaG DNA primase FTH_1028 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 115314648 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase FTH_0799 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 115315379 Common nusG transcription antitermination protein NusG FTH_1689 215 COG0250 NusG, Transcription antiterminator Transcription 115314177 Common rpsC 30S ribosomal protein S3 FTH_0237 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 115314499 Common - probable multidrug ABC superfamily ATP binding cassette transporter, membrane protein FTH_0627 154 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 115314121 Common efp protein-synthesizing GTPase FTH_0176 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 115315308 Common - RND family efflux transporter, MFP subunit FTH_1612 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 115314706 Common clpP endopeptidase Clp FTH_0877 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 115314934 Common lasT rRNA methyltransferase FTH_1157 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 115314849 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase FTH_1047 221 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 115315475 Common - HAAAP family tyrosine:proton (H+) symporter FTH_1801 34 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 115314798 Common - OxyR/LysR oxidative stress transcriptional regulator FTH_0989 190 COG0583 LysR, Transcriptional regulator Transcription 115314107 Common - hypothetical protein FTH_0161 27 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 115315282 Common - LysR family transcriptional regulator FTH_1578 187 COG0583 LysR, Transcriptional regulator Transcription 115314994 Common - short chain dehydrogenase FTH_1222 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 115314449 Common - hypothetical protein FTH_0564 47 COG3496 COG3496, Uncharacterized conserved protein Function unknown 115315410 Common sodB superoxide dismutase FTH_1728 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 115315112 Common - hypothetical protein FTH_1374 131 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 115315417 Common atpH H(+)-transporting two-sector ATPase FTH_1735 180 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 115315301 Common deoB phosphopentomutase FTH_1605 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 115315180 Common - SulP family sulfate permease FTH_1454 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 115315022 Common gshB glutathione synthetase FTH_1256 121 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 115313991 Common - possible OraA/RecX protein FTH_0013 48 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 115314915 Pathogen - hypothetical protein FTH_1135 1 None None None 115314257 Common - probable 2-methylthioadenine synthetase FTH_0335 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 115314603 Common - short chain dehydrogenase FTH_0745 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 115314431 Pathogen - hypothetical protein FTH_0544 4 None None None 115314728 Common grxB glutaredoxin 2 FTH_0903 19 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 115314100 Common - hypothetical protein FTH_0151 17 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 115315040 Common - hypothetical protein FTH_1278 10 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 115315319 Common isftu1 ISFtu1 transposase FTH_1626 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314998 Common - hypothetical protein FTH_1226 77 COG0393 COG0393, Uncharacterized conserved protein Function unknown 115315062 Pathogen - hypothetical protein FTH_1306 1 None None None 115314479 Common wecE ECA biosynthesis protein FTH_0601 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 115314023 Pathogen - hypothetical protein FTH_0055 1 None None None 115314229 Pathogen - hypothetical protein FTH_0304 1 None None None 115315105 Common rpmI ribosomal protein L35 FTH_1367 5 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 115314986 Common infA protein-synthesizing GTPase FTH_1213 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 115314533 Common gltB glutamate synthase (NADPH) FTH_0667 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 115314402 Common - hypothetical protein FTH_0510 2 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 115315355 Common parE DNA topoisomerase IV subunit B FTH_1665 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 115315220 Common - hypothetical protein FTH_1500 39 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 115314941 Common hemY probable protoporphyrinogen oxidase FTH_1164 7 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 115314955 Common - hypothetical protein FTH_1178 2 None None None 115315125 Common - glycosyltransferase FTH_1387 210 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 115314871 Common - leucyl aminopeptidase FTH_1081 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 115315120 Common - S51 family peptidase FTH_1382 32 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 115314165 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase FTH_0225 174 COG0756 Dut, dUTPase Nucleotide transport and metabolism 115314409 Common minC septum site-determining protein MinC FTH_0517 75 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 115314078 Pathogen - hypothetical protein FTH_0125 1 None None None 115314302 Common purK phosphoribosylaminoimidazole carboxylase FTH_0391 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 115315068 Common - hypothetical protein FTH_1318 136 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 115315154 Common greA transcription elongation factor GreA FTH_1428 204 COG0782 GreA, Transcription elongation factor Transcription 115315247 Common accC acetyl-CoA carboxylase biotin carboxylase subunit FTH_1537 234 COG0439 AccC, Biotin carboxylase Lipid metabolism 115314315 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase FTH_0406 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 115315266 Common isftu1 ISFtu1 transposase FTH_1556 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314470 Common - dTDP-glucose 4,6-dehydratase FTH_0592 176 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 115314358 Common map methionyl aminopeptidase FTH_0456 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 115315185 Common - possible S13 family peptidase FTH_1461 97 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 115315530 Common - hypothetical protein FTH_1879 3 None None None 115314266 Common isftu1 ISFtu1 transposase FTH_0348 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314017 Pathogen - hypothetical protein FTH_0047 1 None None None 115314451 Pathogen - hypothetical protein FTH_0567 1 None None None 115314887 Pathogen - hypothetical protein FTH_1101 1 None None None 115315014 Common bioF 8-amino-7-oxononanoate synthase FTH_1246 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 115314129 Common cyoA cytochrome o ubiquinol oxidase subunit II FTH_0186 127 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 115315163 Common - M16 family peptidase FTH_1437 137 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 115314825 Common ispB octaprenyl-diphosphate synthase FTH_1020 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 115314809 Common rpsR 30S ribosomal protein S18 FTH_1001 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 115315474 Common obgE GTPase ObgE FTH_1800 234 COG0536 Obg, Predicted GTPase General function prediction only 115314855 Pathogen - hypothetical protein FTH_1054 1 None None None 115314791 Pathogen - hypothetical protein FTH_0978 1 None None None 115315087 Common - hypothetical protein FTH_1342 19 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 115315420 Common atpB F0F1 ATP synthase subunit A FTH_1738 204 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 115314004 Common tpmT thiopurine S-methyltransferase FTH_0031 27 None None None 115315257 Common yibK tRNA/rRNA methyltransferase FTH_1547 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 115315277 Common - MFS family major facilitator transporter, possible bicyclomycin exporter FTH_1570 167 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314882 Common - hypothetical protein FTH_1095 8 None None None 115315199 Common - NMN family nicotinamide mononucleotide uptake permease PnuC FTH_1479 13 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 115315270 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase FTH_1561 213 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 115314746 Common - hypothetical protein FTH_0923 6 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 115314813 Common pilF type IV pilus assembly protein FTH_1005 16 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 115315225 Common sucD succinate--CoA ligase (ADP-forming) FTH_1505 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 115315054 Common - hypothetical protein FTH_1296 134 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 115315453 Pathogen - hypothetical protein FTH_1772 1 None None None 115315488 Common - hypothetical protein FTH_1824 52 COG2862 COG2862, Predicted membrane protein Function unknown 115315446 Common nuoB NADH dehydrogenase subunit B FTH_1765 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 115315012 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase FTH_1244 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 115315130 Common waaG glycosyltransferase I (outer core) FTH_1392 136 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 115315380 Common tufA elongation factor Tu FTH_1691 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 115314286 Common msrB methionine sulfoxide reductase B FTH_0372 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 115314202 Common - methylated-DNA--[protein]-cysteine S-methyltransferase FTH_0274 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 115315233 Common - LysR family transcriptional regulator FTH_1516 166 COG0583 LysR, Transcriptional regulator Transcription 115315462 Pathogen - hypothetical protein FTH_1784 1 None None None 115314488 Common ppx exopolyphosphatase FTH_0613 175 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 115314362 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase FTH_0460 96 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 115314455 Common - hypothetical protein FTH_0573 6 None None None 115314077 Common - FeoB family ferrous iron (Fe2+) uptake protein FTH_0124 174 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 115314794 Common - hypothetical protein FTH_0982 9 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 115314901 Common plsX fatty acid/phospholipid synthesis protein FTH_1117 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 115314741 Common - class II aldolase/adducin FTH_0918 110 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 115315132 Common - sugar transferase family protein FTH_1394 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 115315447 Common nuoA NADH dehydrogenase I, A subunit FTH_1766 157 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 115315152 Common ftsH/hflB M41 family endopeptidase FtsH/HflB FTH_1424 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 115314821 Pathogen - hypothetical protein FTH_1016 1 None None None 115314022 Common - nitroreductase FTH_0054 75 COG0778 NfnB, Nitroreductase Energy production and conversion 115314415 Pathogen - hypothetical protein FTH_0523 1 None None None 115315404 Common sdhA succinate dehydrogenase FTH_1722 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 115314201 Common gabP APC family amino acid-polyamine-organocation transporter FTH_0272 62 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 115314870 Common - probable outer membrane protein TolC FTH_1080 35 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 115314253 Pathogen - hypothetical protein FTH_0331 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 115314685 Common - 1-aminocyclopropane-1-carboxylate deaminase FTH_0847 27 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 115314877 Common - hypothetical protein FTH_1090 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 115315457 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B FTH_1776 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 115315241 Common xasA probable glutamate:gamma-aminobutyric acid APC family amino acid-polyamine-organocation transporter FTH_1529 72 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 115314886 Common - possible transcriptional regulator FTH_1100 19 COG1396 HipB, Predicted transcriptional regulators Transcription 115315426 Common hisS histidyl-tRNA synthetase FTH_1744 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314977 Pathogen - hypothetical protein FTH_1203 3 None None None 115314473 Common - galacturonosyltransferase FTH_0595 194 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 115314924 Pathogen pdpA1 hypothetical protein FTH_1144 3 None None None 115314210 Pathogen - hypothetical protein FTH_0283 1 None None None 115314458 Common pncB hypothetical protein FTH_0579 23 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 115315186 Common glpT MFS family major facilitator transporter, glycerol-3-phosphate uniporter FTH_1462 74 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115314590 Common - 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase FTH_0729 145 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 115314000 Common pyrB aspartate carbamoyltransferase FTH_0027 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 115314401 Common - possible BolA family transcriptional regulator FTH_0509 16 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 115315260 Common holB DNA-directed DNA polymerase FTH_1550 66 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 115314838 Common - hypothetical protein FTH_1035 43 COG2921 COG2921, Uncharacterized conserved protein Function unknown 115314537 Common - ATP-dependent DNA helicase FTH_0671 69 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 115314355 Common rpsU 30S ribosomal protein S21 FTH_0453 88 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 115314122 Common - oligoribonuclease FTH_0177 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 115314057 Pathogen - hypothetical protein FTH_0098 1 None None None 115315128 Common - bifunctional phosphoserine phosphatase/sugar nucleotidyltransferase FTH_1390 46 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 115314441 Common rnc ribonuclease III FTH_0555 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 115315395 Pathogen - hypothetical protein FTH_1713 1 None None None 115314208 Common - DMT superfamily drug/metabolite transporter FTH_0281 92 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 115314170 Common rpsJ 30S ribosomal protein S10 FTH_0230 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 115314938 Common mglA macrophage growth locus protein subunit A FTH_1161 62 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 115315437 Common nuoK NADH dehydrogenase (ubiquinone) FTH_1756 31 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 115314992 Common - hypothetical protein FTH_1220 17 COG3608 COG3608, Predicted deacylase General function prediction only 115314094 Common ispE 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase FTH_0144 168 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 115314812 Common - probable Fe-S-cluster oxidoreductase FTH_1004 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 115314725 Common - hypothetical protein FTH_0900 23 None None None 115315473 Common - APC family amino acid-polyamine-organocation transporter FTH_1799 44 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 115314102 Common - hypothetical protein FTH_0154 99 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 115314223 Pathogen - hypothetical protein FTH_0296 1 None None None 115314375 Common gcvT glycine cleavage system aminomethyltransferase T FTH_0475 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 115315067 Pathogen - hypothetical protein FTH_1317 1 None None None 115315169 Common - bifunctional FAD/FMN dehydrogenase/Fe-S oxidoreductase FTH_1443 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 115314343 Common - hypothetical protein FTH_0441 3 None None None 115314663 Common cinA probable competence/damage inducible protein CinA FTH_0820 148 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 115314802 Common serC phosphoserine aminotransferase FTH_0993 116 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 115314831 Common rpsU 30S ribosomal protein S21 FTH_1026 94 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 115315174 Pathogen - hypothetical protein FTH_1448 1 None None None 115315386 Common qseC sensor kinase FTH_1701 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 115315027 Pathogen - hypothetical protein FTH_1262 1 None None None 115315251 Common ksgA dimethyladenosine transferase FTH_1541 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 115314154 Common fumC fumarate hydratase FTH_0212 220 COG0114 FumC, Fumarase Energy production and conversion 115314948 Common isftu1 ISFtu1 transposase FTH_1171 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315314 Pathogen - hypothetical protein FTH_1621 1 None None None 115315412 Common - hypothetical protein FTH_1730 9 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 115314606 Common - hypothetical protein FTH_0748 4 None None None 115314317 Pathogen - hypothetical protein FTH_0408 1 None None None 115314950 Common pheS phenylalanyl-tRNA synthetase subunit alpha FTH_1173 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 115314143 Common - hypothetical protein FTH_0200 35 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 115314650 Common - MFS family major facilitator transporter FTH_0801 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115315217 Common gyrB DNA topoisomerase (ATP-hydrolyzing) FTH_1497 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 115314502 Common - bifunctional RhtB family homoserine/threonine resistance transporter FTH_0630 44 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 115314305 Common glk glucokinase FTH_0396 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 115314846 Common - possible bifunctional phosphorylase/lipase FTH_1043 181 COG0657 Aes, Esterase/lipase Lipid metabolism 115314262 Common - hypothetical protein FTH_0341 38 COG4338 COG4338, Uncharacterized protein conserved in bacteria Function unknown 115315084 Common hslR heat shock protein HslR FTH_1339 101 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 115315206 Common - hypothetical protein FTH_1486 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 115314912 Pathogen iglD1 intracellular growth locus D protein FTH_1132 1 None None None 115315116 Common - possible capsule biosynthesis protein FTH_1378 8 None None None 115314517 Common proS prolyl-tRNA synthetase FTH_0650 219 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314145 Common pcp pyroglutamyl-peptidase I FTH_0202 55 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 115314116 Common - hypothetical protein FTH_0171 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 115314446 Common - hypothetical protein FTH_0561 20 None None None 115315513 Common - ABC superfamily ATP binding cassette transporter, binding protein FTH_1855 125 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 115315492 Common dnaX DNA-directed DNA polymerase FTH_1828 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 115315098 Common galK galactokinase FTH_1359 87 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 115314635 Pathogen - hypothetical protein FTH_0785 1 None None None 115315509 Common purA adenylosuccinate synthase FTH_1850 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 115315296 Common prfC peptide chain release factor 3 FTH_1600 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 115314307 Common - hypothetical protein FTH_0398 11 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 115315317 Common - MFS family major facilitator transporter FTH_1624 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314561 Common - ABC superfamily ATP binding cassette transporter, binding protein FTH_0698 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 115315451 Common lysA2 diaminopimelate decarboxylase FTH_1770 206 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 115314088 Common - hypothetical protein FTH_0137 4 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 115314032 Common rpsT 30S ribosomal protein S20 FTH_0066 206 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 115314348 Pathogen - hypothetical protein FTH_0446 1 None None None 115314337 Pathogen - hypothetical protein FTH_0432 1 None None None 115314827 Common - hypothetical protein FTH_1022 156 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 115314015 Common pyrF orotidine-5'-phosphate decarboxylase FTH_0045 155 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 115315500 Common - translation factor SUA5 FTH_1836 122 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 115314277 Pathogen - hypothetical protein FTH_0363 1 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 115314862 Common tspO tryptophan-rich sensory protein FTH_1068 64 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 115315330 Common glpX fructose 1,6-bisphosphatase II FTH_1638 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 115315271 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase FTH_1562 224 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 115315463 Pathogen - hypothetical protein FTH_1785 1 None None None 115315506 Pathogen - hypothetical protein FTH_1845 1 None None None 115314569 Pathogen - hypothetical protein FTH_0707 1 None None None 115314005 Common pyrC dihydroorotase FTH_0032 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 115314050 Common clpB endopeptidase Clp FTH_0089 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 115314272 Pathogen - hypothetical protein FTH_0354 1 None None None 115314687 Common - DAACS family dicarboxylate/amino acid:sodium (Na+) or proton (H+) symporter FTH_0851 162 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 115315278 Pathogen - hypothetical protein FTH_1571 1 COG3619 COG3619, Predicted membrane protein Function unknown 115313988 Common - sulfur transferase FTH_0010 91 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 115314045 Common - acyltransferase FTH_0083 155 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 115314836 Pathogen - hypothetical protein FTH_1033 1 None None None 115314246 Common - peptidylprolyl isomerase FTH_0324 133 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 115314583 Common recO DNA repair protein RecO FTH_0722 30 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 115314623 Common typA tyrosine phosphoprotein TypA FTH_0769 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 115314398 Common - rRNA methyltransferase FTH_0506 211 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 115314330 Common rrmJ ribosomal large subunit methyltransferase J FTH_0425 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 115314215 Common - hypothetical protein FTH_0288 54 None None None 115314295 Common - type IV pili fiber protein FTH_0384 31 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 115314310 Pathogen - hypothetical protein FTH_0401 1 None None None 115315343 Pathogen - hypothetical protein FTH_1653 1 None None None 115315235 Common trxB thioredoxin-disulfide reductase FTH_1519 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 115314975 Pathogen - hypothetical protein FTH_1201 1 None None None 115314244 Common aspD aspartate aminotransferase FTH_0320 144 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 162139938 Common rpmE 50S ribosomal protein L31 FTH_1275 208 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 115315060 Common alr alanine racemase FTH_1303 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 115314922 Pathogen - hypothetical protein FTH_1142 1 None None None 115314190 Common rplO 50S ribosomal protein L15 FTH_0250 217 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 115314133 Common cyoE protoheme IX farnesyltransferase FTH_0190 173 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 115314737 Common - hypothetical protein FTH_0913 5 None None None 115314969 Pathogen - hypothetical protein FTH_1195 1 None None None 115314472 Common - UDP-glucose 4-epimerase FTH_0594 107 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 115314261 Common - probable deoxyribodipyrimidine photo-lyase family protein FTH_0340 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 115315258 Common hemB delta-aminolevulinic acid dehydratase FTH_1548 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 115315435 Common nuoM NADH dehydrogenase (ubiquinone) FTH_1754 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 115314800 Common - short chain dehydrogenase FTH_0991 75 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 115314730 Common lipA lipoyl synthase FTH_0906 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 115314761 Common lplA lipoate--protein ligase A FTH_0944 60 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 115314413 Common recG ATP-dependent DNA helicase RecG FTH_0521 215 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 115314268 Common ubiA prenyltransferase FTH_0350 173 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 115315212 Common - probable acyl-coenzyme A synthetase FTH_1492 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 115314399 Common isftu1 ISFtu1 transposase FTH_0507 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314857 Pathogen - hypothetical protein FTH_1057 1 None None None 115315219 Common dusA tRNA-dihydrouridine synthase A FTH_1499 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 115314462 Common fadA acetyl-CoA acetyltransferase FTH_0583 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 115314764 Common isftu1 ISFtu1 transposase FTH_0947 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314373 Common lolD lipoprotein ABC superfamily ATP binding cassette transporter, binding protein FTH_0473 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 115314038 Common ribA GTP-cyclohydrolase II FTH_0072 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 115314061 Pathogen iglC2 intracellular growth locus C protein FTH_0105 1 None None None 115315029 Common isftu1 ISFtu1 transposase FTH_1264 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315286 Pathogen - hypothetical protein FTH_1583 1 None None None 115315347 Common isftu1 ISFtu1 transposase FTH_1657 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315108 Common - multifunctional chitinase FTH_1370 25 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 115314894 Common - hypothetical protein FTH_1109 13 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115313993 Common ackA acetate kinase FTH_0015 162 COG0282 ackA, Acetate kinase Energy production and conversion 115314320 Common - hypothetical protein FTH_0413 21 COG3737 COG3737, Uncharacterized conserved protein Function unknown 115314526 Common gloB hydroxyacylglutathione hydrolase FTH_0660 207 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 115314549 Pathogen - hypothetical protein FTH_0686 1 None None None 115315361 Common - acid phosphatase FTH_1671 8 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 115315045 Common pyrG CTP synthetase FTH_1283 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 115314640 Common - possible type IV pilus glycosylase FTH_0791 3 None None None 115314010 Common - probable multidrug efflux pump FTH_0038 130 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 115314469 Common hrpA ATP-dependent helicase HrpA FTH_0590 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 115315074 Common cspA cold shock protein FTH_1326 180 COG1278 CspC, Cold shock proteins Transcription 115315522 Pathogen - hypothetical protein FTH_1866 1 None None None 115314917 Pathogen - hypothetical protein FTH_1137 1 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 115314367 Pathogen - hypothetical protein FTH_0466 1 None None None 115315156 Common pgi glucose-6-phosphate isomerase FTH_1430 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 115315103 Common - hypothetical protein FTH_1365 72 COG0398 COG0398, Uncharacterized conserved protein Function unknown 115314595 Common gloA lactoylglutathione lyase FTH_0734 137 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 115314983 Common - APC family amino acid-polyamine-organocation transporter FTH_1210 68 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 115315048 Pathogen - hypothetical protein FTH_1287 1 None None None 115314512 Common nusB N utilization substance protein B FTH_0644 122 COG0781 NusB, Transcription termination factor Transcription 115314691 Pathogen - hypothetical protein FTH_0856 1 None None None 115314541 Common panD aspartate alpha-decarboxylase FTH_0675 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 115314183 Common rplE 50S ribosomal protein L5 FTH_0243 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 115314891 Pathogen - possible acetyltransferase FTH_1105 1 None None None 115315194 Common - HAAAP family serine permease FTH_1474 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 115315192 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase FTH_1472 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 115315003 Pathogen - hypothetical protein FTH_1232 2 None None None 115314327 Common parB chromosome partition protein B FTH_0421 181 COG1475 Spo0J, Predicted transcriptional regulators Transcription 115314108 Common - hypothetical protein FTH_0162 21 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 115314963 Pathogen - hypothetical protein FTH_1188 1 None None None 115315320 Pathogen - hypothetical protein FTH_1627 1 None None None 115314904 Common tktA transketolase FTH_1120 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 115315303 Common polA DNA-directed DNA polymerase FTH_1607 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 115314486 Common rho transcription termination factor Rho FTH_0611 211 COG1158 Rho, Transcription termination factor Transcription 115314578 Common thyA thymidylate synthase FTH_0717 138 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 115314437 Common - xanthine triphosphate pyrophosphatase FTH_0550 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 115315353 Common - hypothetical protein FTH_1663 117 COG1520 COG1520, FOG: WD40-like repeat Function unknown 115314440 Common lepB signal peptidase I FTH_0554 211 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 115314388 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase FTH_0488 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 115314507 Common - probable metal-dependent hydrolase FTH_0638 205 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 115315016 Common bioD dethiobiotin synthase FTH_1248 150 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 115315093 Common nadA quinolinate synthetase FTH_1352 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 115314040 Common ribD bifunctional 5-amino-6-(5-phosphoribosylamino)uracil reductase/ diaminohydroxyphosphoribosylaminopyrimidine deaminase FTH_0074 226 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 115315371 Pathogen - hypothetical protein FTH_1681 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 115315533 Common trpG2 anthranilate synthase component II FTH_1882 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 115315283 Common - probable chitinase FTH_1579 20 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 115314164 Common - phosphatidate cytidylyltransferase FTH_0224 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 115314236 Common aceF dihydrolipoamide acetyltransferase FTH_0311 198 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 115314433 Common - hypothetical protein FTH_0546 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 115315405 Common sdhD succinate dehydrogenase FTH_1723 50 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 115314665 Common - possible tetrahydrofolylpolyglutamate synthase FTH_0822 159 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 115314789 Common phnA phosphonoacetate hydrolase FTH_0976 94 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 115314884 Pathogen - hypothetical protein FTH_1098 3 None None None 115315133 Common rpe ribulose-phosphate 3-epimerase FTH_1395 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 115314718 Pathogen - hypothetical protein FTH_0891 1 None None None 115315441 Common nuoG NADH dehydrogenase subunit G FTH_1760 196 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 115314465 Common fadD1 long-chain-fatty-acid--CoA ligase FTH_0586 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 115315238 Common - possible GTP-binding protein FTH_1526 163 COG1162 COG1162, Predicted GTPases General function prediction only 115315176 Common cydD cysteine/glutathione ABC transporter membrane/ATP-binding component FTH_1450 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 115314806 Common hemF coproporphyrinogen III oxidase FTH_0997 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 115315051 Common fopA outer membrane protein FopA FTH_1293 62 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 115314773 Common - hypothetical protein FTH_0958 6 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 115315243 Common recJ single-stranded-DNA-specific exonuclease RecJ FTH_1531 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 115315222 Pathogen - hypothetical protein FTH_1502 1 None None None 115314124 Common - hypothetical protein FTH_0181 106 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 115314443 Common rnr ribonuclease R FTH_0557 193 COG0557 VacB, Exoribonuclease R Transcription 115315058 Common - hypothetical protein FTH_1300 117 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 115315424 Common - ATPase FTH_1742 95 COG1485 COG1485, Predicted ATPase General function prediction only 115314475 Common - UDP-glucose 4-epimerase FTH_0597 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 115315306 Common cca tRNA CCA-pyrophosphorylase FTH_1610 198 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 115315018 Common - possible transcriptional regulator FTH_1250 130 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 115315097 Common galT galactose-1-phosphate uridylyltransferase FTH_1358 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 115314530 Common - prophage repressor protein FTH_0664 14 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 115314799 Common - peroxiredoxin FTH_0990 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 115314403 Common - hypothetical protein FTH_0511 40 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 115315494 Common ftsZ cell division protein FtsZ FTH_1830 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 115315231 Common cutC CutC family copper (Cu2+) homeostasis protein FTH_1514 57 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 115315229 Common ddlA D-alanine--D-alanine ligase FTH_1509 22 COG0439 AccC, Biotin carboxylase Lipid metabolism 115314771 Common - type I site-specific deoxyribonuclease FTH_0955 107 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 115314539 Common recD exodeoxyribonuclease V FTH_0673 142 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 115315262 Common gst glutathione S-transferase FTH_1552 80 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 115314945 Common dnaJ2 chaperone DnaJ FTH_1168 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 115314059 Common iglA2 intracellular growth locus A protein FTH_0103 46 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 115315023 Common fmt methionyl-tRNA formyltransferase FTH_1257 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 115314104 Common isftu1 ISFtu1 transposase FTH_0157 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314350 Pathogen - hypothetical protein FTH_0448 1 None None None 115315167 Common udp uridine phosphorylase FTH_1441 99 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 115314962 Common - hypothetical protein FTH_1187 15 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 115314289 Common - APC family amino acid-polyamine-organocation transporter FTH_0375 100 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 115315450 Common - possible MFS family major facilitator transporter, multidrug resistance protein FTH_1769 34 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314823 Pathogen - hypothetical protein FTH_1018 1 None None None 115314748 Common rplY 50S ribosomal protein L25 FTH_0928 165 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 115315252 Common surA peptidylprolyl isomerase FTH_1542 101 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 115315137 Common fabI enoyl-[acyl-carrier-protein] reductase (NADH) FTH_1403 227 COG0623 FabI, Enoyl- acyl-carrier-protein 115314002 Common carA carbamoyl phosphate synthase small subunit FTH_0029 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 115314844 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_1041 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 115315203 Common rpoZ DNA-directed RNA polymerase FTH_1483 110 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 115314024 Common - hypothetical protein FTH_0056 13 COG3619 COG3619, Predicted membrane protein Function unknown 115314341 Common - hypothetical protein FTH_0438 69 COG0431 COG0431, Predicted flavoprotein General function prediction only 115315384 Common glpA glycerol-3-phosphate dehydrogenase FTH_1696 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 115315312 Common - hypothetical protein FTH_1617 56 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 115315333 Common - hypothetical protein FTH_1641 16 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 115314489 Pathogen - hypothetical protein FTH_0615 1 None None None 115315481 Common isftu1 ISFtu1 transposase FTH_1815 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314206 Pathogen - hypothetical protein FTH_0278 1 None None None 115314181 Common rplN 50S ribosomal protein L14 FTH_0241 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 115314148 Common valS valyl-tRNA synthetase FTH_0205 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115315082 Common - hypothetical protein FTH_1335 19 None None None 115314264 Common - hypothetical protein FTH_0345 11 None None None 115314110 Pathogen - hypothetical protein FTH_0164 1 None None None 115315216 Common - pyridoxine biosynthesis protein FTH_1496 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 115315158 Common guaB IMP dehydrogenase FTH_1432 237 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 115314815 Pathogen - hypothetical protein FTH_1007 1 None None None 115314076 Common ppdK pyruvate phosphate dikinase FTH_0123 232 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 115314990 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase FTH_1217 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 115315184 Common isftu1 ISFtu1 transposase FTH_1459 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315471 Common - MFS family major facilitator transporter, probable multidrug resistance protein FTH_1796 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314151 Common lldD L-lactate dehydrogenase (cytochrome) FTH_0209 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 115315515 Common wrbA multimeric flavodoxin WrbA FTH_1858 112 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 115314601 Pathogen - hypothetical protein FTH_0742 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 115314708 Common lon endopeptidase La FTH_0879 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 115314119 Common - acyltransferase FTH_0174 101 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 115314672 Common - probable hydrolase FTH_0834 102 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 115314931 Pathogen - hypothetical protein FTH_1154 1 None None None 115315373 Common rpoB DNA-directed RNA polymerase subunit beta FTH_1683 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 115315102 Common isftu1 ISFtu1 transposase FTH_1364 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314952 Common fur1 ferric (Fe3+) uptake regulator protein FTH_1175 107 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 115314683 Common - carbonate dehydratase FTH_0845 144 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 115314979 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_1206 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 115314329 Common - hypothetical protein FTH_0423 36 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 115314175 Common rpsS 30S ribosomal protein S19 FTH_0235 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 115314377 Common gcvP1 glycine dehydrogenase subunit 1 FTH_0477 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 115314493 Pathogen - hypothetical protein FTH_0619 1 None None None 115314674 Common - preprotein translocase subunit FTH_0836 176 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 115314225 Pathogen - hypothetical protein FTH_0298 1 None None None 115314370 Common def1 peptide deformylase FTH_0470 199 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 115315431 Common hemE uroporphyrinogen decarboxylase FTH_1749 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 115315121 Common - sugar kinase FTH_1383 147 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 115315393 Common hemN coproporphyrinogen oxidase FTH_1711 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 115315414 Common atpD F0F1 ATP synthase subunit beta FTH_1732 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 115314293 Common recN DNA repair protein RecN FTH_0380 212 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 115314242 Pathogen - hypothetical protein FTH_0318 1 None None None 115315189 Pathogen - hypothetical protein FTH_1468 1 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 115314392 Common thrC threonine synthase FTH_0495 211 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 115315470 Common yegQ family U32 peptidase FTH_1795 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 115314241 Pathogen - hypothetical protein FTH_0317 1 None None None 115314981 Common - probable transcriptional regulator FTH_1208 134 COG1959 COG1959, Predicted transcriptional regulator Transcription 115314280 Pathogen - hypothetical protein FTH_0366 1 None None None 115314929 Common trmE tRNA modification GTPase TrmE FTH_1152 227 COG0486 ThdF, Predicted GTPase General function prediction only 115314920 Common - hypothetical protein FTH_1140 9 None None None 115314423 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase FTH_0536 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 115314736 Common rmuC DNA recombination protein RmuC FTH_0912 142 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 115314581 Common iscS cysteine desulfarase FTH_0720 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 115314967 Common - crossover junction endodeoxyribonuclease FTH_1192 92 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 115314192 Common rpsM 30S ribosomal protein S13 FTH_0253 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 115315210 Pathogen - hypothetical protein FTH_1490 1 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 115313986 Common - S49 family protease FTH_0008 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 115315391 Common - probable peroxidase FTH_1709 47 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 115314860 Common - hypothetical protein FTH_1064 14 None None None 115314098 Pathogen - hypothetical protein FTH_0149 1 None None None 115314630 Common nagA glutaminase FTH_0780 120 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 115315091 Common nadB L-aspartate oxidase FTH_1350 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 115314621 Common ggt gamma-glutamyltransferase FTH_0767 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 115314220 Common secB2 preprotein translocase subunit SecB FTH_0293 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 115314859 Pathogen - hypothetical protein FTH_1061 1 None None None 115315341 Common groEL chaperonin GroEL FTH_1651 243 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 115315284 Common ubiG 3-demethylubiquinone-9 3-methyltransferase FTH_1581 122 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 115314628 Common - possible lipoprotein FTH_0778 2 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 115314158 Common folA dihydrofolate reductase FTH_0218 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 115314232 Common trpS tryptophanyl-tRNA synthetase FTH_0307 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115314060 Common iglB2 intracellular growth locus B protein FTH_0104 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 115314047 Pathogen - hypothetical protein FTH_0085 1 None None None 115314896 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase FTH_1112 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 115315345 Pathogen - hypothetical protein FTH_1655 1 None None None 115314919 Common - hypothetical protein FTH_1139 4 None None None 115314758 Common hslU ATP-dependent protease ATP-binding subunit FTH_0941 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 115314007 Pathogen - hypothetical protein FTH_0035 1 None None None 115315504 Common - possible conserved hypothetical YGGT family membrane protein FTH_1843 90 None None None 115314173 Common rplW 50S ribosomal protein L23 FTH_0233 214 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 115314335 Common maeA malate dehydrogenase (oxaloacetate-decarboxylating) FTH_0430 193 COG0281 SfcA, Malic enzyme Energy production and conversion 115314412 Pathogen - conserved hypothetical lipoprotein FTH_0520 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 115314957 Common - cardiolipin synthase FTH_1180 154 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 115315298 Common nupC1 CNT family concentrative nucleoside transporter, membrane protein FTH_1602 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 115314198 Common isftu1 ISFtu1 transposase FTH_0262 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314723 Common - possible TEGT family testis enhanced gene transfer tranporter FTH_0898 79 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 115314322 Pathogen - hypothetical protein FTH_0416 1 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 115314231 Pathogen - hypothetical protein FTH_0306 1 None None None 115314135 Common - hypothetical protein FTH_0192 5 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 115314290 Common - probable mannose-6-phosphate isomerase FTH_0376 124 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 115314563 Common - hypothetical protein FTH_0700 34 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 115314274 Common htpX heat shock protein HtpX FTH_0356 182 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 115315005 Common trpG1 anthranilate synthase FTH_1236 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 115315368 Common metK S-adenosylmethionine synthetase FTH_1678 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 115314906 Common pgk phosphogylcerate kinase FTH_1122 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 115315329 Common putP SSS family solute:sodium (Na+) symporter FTH_1637 173 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 115315304 Common lpxK tetraacyldisaccharide 4'-kinase FTH_1608 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 115314519 Pathogen - hypothetical protein FTH_0653 1 None None None 115315196 Common ftsB cell division initiator protein FtsB FTH_1476 56 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 115315269 Common ftsW cell division protein FtsW FTH_1560 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 115314559 Pathogen - hypothetical protein FTH_0696 1 None None None 115314514 Pathogen - hypothetical protein FTH_0646 1 None None None 115314652 Common chaB cation transport regulator FTH_0804 21 COG4572 ChaB, Putative cation transport regulator General function prediction only 115314066 Pathogen - hypothetical protein FTH_0110 1 None None None 115314086 Pathogen - hypothetical protein FTH_0135 1 None None None 115315001 Common folE GTP cyclohydrolase I FTH_1230 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 115314279 Common gpsA glycerol-3-phosphate dehydrogenase (NAD(P)(+)) FTH_0365 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 115315338 Pathogen - hypothetical protein FTH_1646 1 None None None 115314238 Common isftu1 ISFtu1 transposase FTH_0314 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315460 Pathogen - hypothetical protein FTH_1781 1 None None None 115314439 Common - two-component response regulator FTH_0553 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 115314505 Common - possible transcriptional regulator FTH_0635 90 COG0640 ArsR, Predicted transcriptional regulators Transcription 115315358 Common - dinucleoside polyphosphate hydrolase FTH_1668 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 115314618 Common - hypothetical protein FTH_0764 62 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 115314195 Common rpoA1 DNA-directed RNA polymerase subunit alpha FTH_0256 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 115313996 Common aspS aspartyl-tRNA synthetase FTH_0020 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 115315073 Pathogen - hypothetical protein FTH_1325 1 None None None 115315363 Common xerD site specific recombinase XerD FTH_1673 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 115314406 Common - ABC superfamily ATP binding casette transporter, ABC protein FTH_0514 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 115314571 Pathogen - hypothetical protein FTH_0709 1 None None None 115314353 Common glmS glutamine--fructose-6-phosphate transaminase (isomerizing) FTH_0451 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 115314528 Common feoA iron (Fe2+) transport protein A FTH_0662 3 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 115315535 Common trpR tryptophan operon repressor TrpR FTH_1884 21 COG2973 TrpR, Trp operon repressor Transcription 115315031 Common - oxidoreductase FTH_1267 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 115315041 Common - probable ATP-binding protein FTH_1279 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 115315078 Pathogen - hypothetical protein FTH_1330 1 None None None 115314611 Common - possible transglutaminase FTH_0755 115 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 115315034 Pathogen - hypothetical protein FTH_1271 1 None None None 115315524 Common - probable zinc (Zn2+)-dependent hydrolase FTH_1868 85 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 115314365 Common slt soluble lytic murein transglycosylase FTH_0463 157 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 115315224 Common sucC succinyl-CoA synthetase subunit beta FTH_1504 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 115314500 Common - possible glycosyltransferase FTH_0628 171 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 115315469 Common pcm protein-L-isoaspartate(D-aspartate) O-methyltransferase FTH_1794 119 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 115314597 Common rpiA ribose-5-phosphate isomerase A FTH_0738 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 115314657 Common hemH ferrochelatase FTH_0813 159 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 115314661 Common pilB type IV pilus assembly protein FTH_0818 214 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 115314756 Common - soluble pyridine nucleotide transhydrogenase FTH_0938 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 115315124 Common - glycosyltransferase FTH_1386 215 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 115314319 Common prlC M3 family oligopeptidase A FTH_0412 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 115314868 Pathogen - hypothetical protein FTH_1078 1 None None None 115315399 Common mrsA phosphoglucomutase FTH_1717 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 115314775 Common dinB DNA-directed DNA polymerase FTH_0960 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 115314360 Common - hypothetical protein FTH_0458 9 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 115314954 Common zupT probable ZIP family zinc (Zn2+)-iron (Fe2+) permease FTH_1177 6 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 115314729 Common ftnA ferritin protein FTH_0905 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 115314090 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_0139 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 115314029 Common - MFS family major facilitator transporter FTH_0062 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314632 Common - GMP synthase (glutamine-hydrolyzing) FTH_0782 53 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 115313998 Common - HAAAP family serine/threonine permease FTH_0024 37 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 115315478 Common kdpA potassium-transporting ATPase subunit A FTH_1808 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 115315181 Common - MFS family major facilitator transporter FTH_1456 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115315416 Common atpA F0F1 ATP synthase subunit alpha FTH_1734 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 115315290 Common - MFS family major facilitator transporter FTH_1589 84 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314379 Common aroE2 shikimate dehydrogenase FTH_0479 123 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 115314999 Common - POT family proton dependent peptide transporter FTH_1228 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 115315080 Common - hypothetical protein FTH_1333 5 COG1289 COG1289, Predicted membrane protein Function unknown 115315318 Common - probable acetyltransferase FTH_1625 4 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 115314933 Common - possible SSPTS family porter component IIA FTH_1156 25 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 115315376 Common rplJ 50S ribosomal protein L10 FTH_1686 214 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 115314072 Pathogen pdpB2 conserved protein PdpB FTH_0117 1 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 115315495 Common ftsA cell division protein FtsA FTH_1831 175 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 115314106 Common - DNA/RNA helicase FTH_0160 170 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 115314666 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase FTH_0823 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 115314987 Common - hypothetical protein FTH_1214 33 COG0730 COG0730, Predicted permeases General function prediction only 115314681 Common rnhA ribonuclease H FTH_0843 180 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 115314804 Common isftu1 ISFtu1 transposase FTH_0995 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115315299 Common nupC2 (pyrimidine) CNT family concentrative nucleoside transporter FTH_1603 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 115315335 Common lolA lipoprotein releasing system, subunit A, outer membrane FTH_1643 79 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 115315281 Pathogen - hypothetical protein FTH_1577 1 None None None 115314097 Pathogen - hypothetical protein FTH_0147 1 None None None 115315390 Common acnA aconitate hydratase FTH_1708 221 COG1048 AcnA, Aconitase A Energy production and conversion 115314258 Pathogen - probable GNAT family acetyltransferase FTH_0336 2 COG2153 ElaA, Predicted acyltransferase General function prediction only 115315356 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase FTH_1666 108 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 115315484 Common blc probable lipocalin FTH_1819 67 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 115314916 Pathogen - hypothetical protein FTH_1136 1 None None None 115314430 Pathogen - hypothetical protein FTH_0543 1 None None None 115314303 Common - intracellular septation protein A FTH_0394 90 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 115315088 Common - glutathione peroxidase FTH_1345 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 115314391 Pathogen - hypothetical protein FTH_0491 1 None None None 115315311 Common - hypothetical protein FTH_1615 6 None None None 115314574 Common - glycosyltransferase FTH_0712 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 115314602 Pathogen - hypothetical protein FTH_0743 1 COG1289 COG1289, Predicted membrane protein Function unknown 115315207 Common pnp polynucleotide phosphorylase/polyadenylase FTH_1487 233 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 115315228 Common - hypothetical protein FTH_1508 10 COG0628 PerM, Predicted permease General function prediction only 115314532 Common - hypothetical protein FTH_0666 90 COG2962 RarD, Predicted permeases General function prediction only 115314745 Common - CPA2 family monovalent cation:proton (H+) antiporter-2 FTH_0922 210 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 115314419 Common res type III site-specific deoxyribonuclease FTH_0531 41 COG3587 COG3587, Restriction endonuclease Defense mechanisms 115314740 Common hdc histidine decarboxylase FTH_0917 24 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 115315400 Common apt adenine phosphoribosyltransferase FTH_1718 165 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 115314018 Common tyrA prephenate dehydrogenase FTH_0048 73 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 115314359 Pathogen - hypothetical protein FTH_0457 1 None None None 115315201 Common rumA 23S rRNA 5-methyluridine methyltransferase FTH_1481 202 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 115314523 Common hemD uroporphyrinogen-III synthase FTH_0657 9 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 115314881 Pathogen - hypothetical protein FTH_1094 1 None None None 115314450 Common - possible oxidase FTH_0565 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 115314205 Common - possible phosphatidylglycerophosphate synthase FTH_0277 68 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 115315166 Common miaE tRNA-(ms(2)io(6)a)-hydroxylase FTH_1440 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 115314422 Common gyrA DNA topoisomerase (ATP-hydrolyzing) FTH_0535 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 115314705 Common tig trigger factor FTH_0876 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 115314850 Common - hypothetical protein FTH_1048 7 None None None 115314410 Common rpmG 50S ribosomal protein L33 FTH_0518 133 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 115314795 Pathogen - hypothetical protein FTH_0983 2 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 115314346 Pathogen - hypothetical protein FTH_0444 1 None None None 115315383 Common glpF MIP family major intrinsic protein channel protein FTH_1695 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 115315135 Common - hypothetical protein FTH_1397 9 COG2259 COG2259, Predicted membrane protein Function unknown 115314716 Common wzb protein-tyrosine-phosphatase FTH_0888 132 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 115315049 Common - hypothetical protein FTH_1289 18 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 115315246 Pathogen - hypothetical protein FTH_1536 1 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 115315139 Pathogen - hypothetical protein FTH_1405 1 None None None 115314786 Common - hypothetical protein FTH_0972 7 None None None 115315443 Common nuoE NADH dehydrogenase (ubiquinone) FTH_1762 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 115315407 Common gltA citrate (Si)-synthase FTH_1725 193 COG0372 GltA, Citrate synthase Energy production and conversion 115314943 Common grpE chaperone GrpE FTH_1166 232 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 115314405 Common - toluene ABC superfamily ATP binding cassette transporter, membrane protein FTH_0513 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 115314834 Common rpoD DNA-directed RNA polymerase sigma subunit RpoD FTH_1029 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 115315025 Common - hypothetical protein FTH_1259 159 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 115315309 Common - RND superfamily resistance-nodulation-cell division:proton (H+) antiporter FTH_1613 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 115314861 Common spoU rRNA methyltransferase FTH_1066 199 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 115314694 Common - M24 family aminopeptidase FTH_0863 188 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 115315336 Pathogen - hypothetical protein FTH_1644 1 None None None 115315434 Common nuoN NADH dehydrogenase (ubiquinone) FTH_1753 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 115315365 Common trmD tRNA (guanine-N(1)-)-methyltransferase FTH_1675 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 115314137 Pathogen - hypothetical protein FTH_0194 1 None None None 115314852 Common - hypothetical protein FTH_1050 13 None None None 115315385 Common - hypothetical protein FTH_1699 2 COG2232 COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase General function prediction only 115314696 Common bla beta-lactamase FTH_0865 63 COG2367 PenP, Beta-lactamase class A Defense mechanisms 115314160 Common tsf elongation factor Ts FTH_0220 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 115315100 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase FTH_1361 153 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 115314363 Pathogen - hypothetical protein FTH_0461 1 None None None 115315168 Common cdd cytidine deaminase FTH_1442 111 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 115315536 Common cafA2 ribonuclease G FTH_1885 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 115314481 Common - PST family polysaccharide transporter FTH_0603 22 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 115314712 Common hfq host factor I protein FTH_0883 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 115314819 Pathogen - hypothetical protein FTH_1012 1 None None None 115314546 Common potC polyamine ABC superfamily ATP binding cassette transporter, membrane protein FTH_0681 200 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 115314613 Pathogen - hypothetical protein FTH_0758 1 None None None 115314873 Common - possible NMC family Nicotinamide mononucleotide uptake permease PnuC FTH_1086 46 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 115314167 Common rpsL 30S ribosomal protein S12 FTH_0227 237 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 115314599 Pathogen - hypothetical protein FTH_0740 1 None None None 115315526 Common hsp heat shock protein FTH_1874 162 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 115314659 Pathogen - hypothetical protein FTH_0815 1 None None None 115315033 Common isftu1 ISFtu1 transposase FTH_1270 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314540 Common - pantothenate kinase FTH_0674 131 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 115314495 Pathogen - hypothetical protein FTH_0622 1 None None None 115314897 Common acpP acyl carrier protein FTH_1113 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 115314536 Pathogen - hypothetical protein FTH_0670 1 None None None 115315328 Common - probable Glycosyltransferase FTH_1636 65 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 115315198 Common - MFS family major facilitator transporter FTH_1478 66 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115314781 Common mdh malate dehydrogenase FTH_0966 190 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 115314890 Pathogen - hypothetical protein FTH_1104 1 None None None 115315175 Pathogen - hypothetical protein FTH_1449 1 None None None 115314389 Common - hypothetical protein FTH_0489 17 None None None 115314112 Common aroE1 shikimate dehydrogenase FTH_0167 101 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 115314592 Common queA queuine tRNA-ribosyltransferase FTH_0731 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 115314189 Common rpmD 50S ribosomal protein L30 FTH_0249 101 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 115314654 Common - hypothetical protein FTH_0807 36 COG1873 COG1873, Uncharacterized conserved protein Function unknown 115314149 Common - hypothetical protein FTH_0206 4 None None None 115314521 Pathogen - hypothetical protein FTH_0655 1 None None None 115314434 Common pcs phosphatidylcholine synthase FTH_0547 25 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 115314647 Common - hypothetical protein FTH_0798 23 COG2938 COG2938, Uncharacterized conserved protein Function unknown 115314551 Common - outer membrane protein FTH_0688 107 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 115315324 Pathogen - hypothetical protein FTH_1631 1 None None None 115314816 Common - dihydrolipoyllysine-residue acetyltransferase FTH_1008 99 COG0456 RimI, Acetyltransferases General function prediction only 115315144 Common - hypothetical protein FTH_1413 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 115314777 Common - probable ABC superfamily ATP binding cassette transporter, ABC protein FTH_0962 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 115314073 Pathogen pdpA2 conserved protein PdpA FTH_0118 3 None None None 115314171 Common rplC 50S ribosomal protein L3 FTH_0231 225 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 115314832 Common - possible GatB domain protein FTH_1027 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 115315517 Common - PnuC family nicotinamide mononucleotide transporter FTH_1860 50 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 115314678 Common rpoH RNA polymerase factor sigma-32 FTH_0840 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 115315505 Common - hypothetical protein FTH_1844 11 None None None 115315293 Common uvrD2 DNA helicase II FTH_1597 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 115314041 Common cybB cytochrome b561 FTH_0078 32 COG3038 CybB, Cytochrome B561 Energy production and conversion 115314639 Pathogen pilN possible type IV pilus-associated protein FTH_0790 1 None None None 115313983 Common dnaN DNA-directed DNA polymerase FTH_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 115315455 Pathogen - probable phospholipase/acyltransferase FTH_1774 5 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 115315148 Pathogen - hypothetical protein FTH_1419 1 None None None 115314498 Common - probable multidrug ABC superfamily ATP binding cassette transporter, ABC protein FTH_0626 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 115315275 Common tet MFS family major facilitator transporter, tetracycline exporter FTH_1568 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314105 Common usp universal stress protein FTH_0159 157 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 115315449 Common iucA/iucC possible siderophore biosynthesis IucA / IucC family protein FTH_1768 50 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 115314643 Common aroK shikimate kinase FTH_0794 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 115314588 Common - hypothetical protein FTH_0727 40 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 115314926 Pathogen - hypothetical protein FTH_1147 1 None None None 115315255 Pathogen - hypothetical protein FTH_1545 1 None None None 115314282 Pathogen - hypothetical protein FTH_0368 1 None None None 115314534 Common recC exodeoxyribonuclease V FTH_0668 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 115314054 Common - probable carboxypeptidase FTH_0094 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 115314765 Common lldA L-lactate dehydrogenase (cytochrome) FTH_0948 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 115314768 Common - probable iron (Fe2+)-dependent alcohol dehydrogenase FTH_0952 166 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 115315161 Common - hypothetical protein FTH_1435 85 COG0795 COG0795, Predicted permeases General function prediction only 115314299 Common purC/purD phosphoribosylaminoimidazolesuccinocarboxamide synthase FTH_0388 234 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 115314219 Pathogen - hypothetical protein FTH_0292 1 None None None 115315065 Common - TatD family deoxyribonuclease FTH_1314 177 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 115314334 Common ribF riboflavin kinase FTH_0429 211 COG0196 RibF, FAD synthase Coenzyme metabolism 115315439 Common nuoI NADH dehydrogenase subunit I FTH_1758 185 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 115314557 Common - hypothetical protein FTH_0694 197 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 115315071 Pathogen - hypothetical protein FTH_1322 1 None None None 115314565 Common - hypothetical protein FTH_0702 120 COG4105 ComL, DNA uptake lipoprotein General function prediction only 115314155 Common gltX glutamate--tRNA ligase FTH_0213 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 115314797 Common - hypothetical protein FTH_0988 26 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 115314841 Common kdsC 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase FTH_1038 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 115314312 Common - hypothetical protein FTH_0403 35 None None None 115314035 Pathogen - hypothetical protein FTH_0069 1 None None None 115314579 Common lgt prolipoprotein diacylglyceryl transferase FTH_0718 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 115314671 Common tgt queuine tRNA-ribosyltransferase FTH_0831 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 115314626 Pathogen - hypothetical protein FTH_0773 1 None None None 115315215 Common - SNO family glutamine amidotransferase FTH_1495 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 115314051 Pathogen - hypothetical protein FTH_0091 1 None None None 115314193 Common rpsK 30S ribosomal protein S11 FTH_0254 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 115314971 Common - hypothetical protein FTH_1197 183 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 115314609 Common - hypothetical protein FTH_0753 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 115315476 Common - hypothetical protein FTH_1802 2 None None None 115314828 Common - hypothetical protein FTH_1023 67 COG0824 FcbC, Predicted thioesterase General function prediction only 115314664 Common cphA cyanophycin synthetase FTH_0821 207 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 115314101 Common ybgK hydrolase subunit FTH_0153 98 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 115314993 Common xthA exodeoxyribonuclease III FTH_1221 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 115315200 Common - probable bifunctional transcriptional regulator/sugar kinase FTH_1480 119 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 115314260 Common - hypothetical protein FTH_0338 23 None None None 115314256 Common - probable OmpA family protein FTH_0334 145 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 115315354 Common - MFS family major facilitator transporter FTH_1664 174 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115315300 Common deoC deoxyribose-phosphate aldolase FTH_1604 137 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 115315511 Common - probable cation ABC superfamily ATP binding cassette transporter, membrane protein FTH_1853 189 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 115314688 Common - probable phosphosugar isomerase FTH_0852 234 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 115314879 Common rdgC recombination associated protein FTH_1092 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 115315205 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase FTH_1485 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 115315086 Pathogen - hypothetical protein FTH_1341 1 None None None 115315111 Common murG undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase FTH_1373 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 115314720 Common ilvH acetolactate synthase FTH_0895 15 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 115314301 Common purE phosphoribosylaminoimidazole carboxylase FTH_0390 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 115315445 Common nuoC NADH dehydrogenase (ubiquinone) FTH_1764 170 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 115314703 Common - probable O-methyltransferase FTH_0873 65 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 115315011 Common - hypothetical protein FTH_1242 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 115315459 Common gatC aspartyl/glutamyl-tRNA (Asn/Gln) amidotransferase subunit C FTH_1778 30 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 115314393 Common speH adenosylmethionine decarboxylase FTH_0497 69 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 115315265 Common - phosphorylase FTH_1555 103 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 115315188 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_1465 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 115315114 Common spoT2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase FTH_1376 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 115315153 Common uvrA UvrABC excinuclease subunit A FTH_1427 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 115314166 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase FTH_0226 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 115314956 Common - cardiolipin synthase FTH_1179 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 115315126 Common - hypothetical protein FTH_1388 10 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 115314942 Common mltA membrane-bound murein transglycosylase FTH_1165 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 115314949 Common - DMT superfamily drug/metabolite transporter FTH_1172 69 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 115314668 Common metIQ D-methionine ABC superfamily ATP binding cassette transporter, membrane/binding protein FTH_0826 105 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 115314070 Pathogen - hypothetical protein FTH_0115 1 None None None 115314374 Common cadA lysine decarboxylase FTH_0474 88 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 115314872 Common talA transaldolase B FTH_1082 168 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 115314928 Pathogen - hypothetical protein FTH_1151 1 None None None 115314453 Pathogen - hypothetical protein FTH_0571 1 None None None 115315397 Common secG preprotein translocase subunit SecG FTH_1715 72 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 115315063 Common - hypothetical protein FTH_1307 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 115314997 Common gor glutathione reductase FTH_1225 237 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 115314120 Pathogen - type IV pilus assembly protein FTH_0175 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 115313992 Common ssb single-stranded DNA binding protein FTH_0014 203 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 115314432 Common - probable glycosyl hydrolase FTH_0545 177 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 115314308 Common ubiB ubiquinone biosynthesis protein FTH_0399 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 115315069 Common galU UTP--glucose-1-phosphate uridylyltransferase FTH_1320 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 115315418 Common atpF H(+)-transporting two-sector ATPase FTH_1736 108 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 115314083 Common hemC hydroxymethylbilane synthase FTH_0132 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 115315497 Common ddlB D-alanine--D-alanine ligase FTH_1833 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 115315013 Common bioB biotin synthase FTH_1245 177 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 115314067 Pathogen - hypothetical protein FTH_0111 1 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 115314935 Common rnhB ribonuclease H FTH_1158 239 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 115314866 Pathogen - hypothetical protein FTH_1075 1 None None None 115315141 Common uvrC UvrABC excinuclease subunit C FTH_1410 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 115314255 Pathogen - hypothetical protein FTH_0333 1 None None None 115315055 Common - HesB family protein FTH_1297 134 COG0316 IscA, Uncharacterized conserved protein Function unknown 115314203 Common - hypothetical protein FTH_0275 26 COG0398 COG0398, Uncharacterized conserved protein Function unknown 115315454 Pathogen - hypothetical protein FTH_1773 1 None None None 115314452 Pathogen - hypothetical protein FTH_0570 1 None None None 115315401 Common sucB dihydrolipoyllysine-residue succinyltransferase FTH_1719 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 115315106 Common infC protein-synthesizing GTPase FTH_1368 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 115314461 Common - hypothetical protein FTH_0582 11 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 115315164 Common - N6-adenine-specific methyltransferase FTH_1438 210 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 115314039 Common ribB riboflavin synthase subunit alpha FTH_0073 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 115314888 Pathogen - hypothetical protein FTH_1102 1 None None None 115315234 Common gph phosphoglycolate phosphatase FTH_1517 212 COG0546 Gph, Predicted phosphatases General function prediction only 115315179 Common tdcF endoribonuclease L-PSP FTH_1453 192 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 115315381 Common - possible MscS family small conductance mechanosenstive ion channel FTH_1693 85 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 115314267 Common - hypothetical protein FTH_0349 20 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 115315499 Common rpsA 30S ribosomal protein S1 FTH_1835 242 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 115314854 Common ruvB Holliday junction DNA helicase B FTH_1052 221 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 115315248 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FTH_1538 179 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 115314604 Common sbcB exodeoxyribonuclease I FTH_0746 52 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 115314701 Common phoH phosphate starvation-inducible protein PhoH FTH_0871 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 115314784 Common - hypothetical protein FTH_0969 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 115315287 Common - hypothetical protein FTH_1585 4 None None None 115314030 Common gmhA phosphoheptose isomerase FTH_0064 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 115314714 Common hflK probable membrane protease subunit HflK FTH_0886 205 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 115314428 Common lpxA UDP-N-acetylglucosamine acyltransferase FTH_0541 156 COG1043 LpxA, Acyl- acyl carrier protein 115315531 Pathogen - hypothetical protein FTH_1880 1 None None None 115314357 Common - hypothetical protein FTH_0455 6 COG1694 MazG, Predicted pyrophosphatase General function prediction only 115315430 Common - hypothetical protein FTH_1748 161 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 115315487 Common glsA glutaminase FTH_1822 89 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 115315226 Pathogen - hypothetical protein FTH_1506 1 None None None 115314128 Common - MFS family major facilitator transporter FTH_0185 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 115314743 Common - possible amidohydrolase/nicotinamidase FTH_0920 5 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 115314918 Pathogen - hypothetical protein FTH_1138 1 None None None 115314417 Pathogen - hypothetical protein FTH_0525 1 None None None 115314407 Common minE cell division topological specificity factor protein MinE FTH_0515 59 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 115314810 Common rplI 50S ribosomal protein L9 FTH_1002 210 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 115314287 Common sodC superoxide dismuate FTH_0373 83 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 115314416 Common fumA fumarate hydratase FTH_0524 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 115314727 Common rnfB NADH:ubiquinone oxidoreductase subunit RnfB FTH_0902 114 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 115315367 Common rpsP 30S ribosomal protein S16 FTH_1677 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 115314478 Common asnB asparagine synthase (glutamine-hydrolyzing) FTH_0600 175 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 115315427 Common rbfA ribosome-binding factor A FTH_1745 158 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 115315388 Common - cytochrome d ubiquinol oxidase subunit II FTH_1704 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 115314226 Common murQ N-acetylmuramic acid-6-phosphate etherase FTH_0299 85 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 115314792 Common dnaQ DNA-directed DNA polymerase FTH_0980 171 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 115314400 Pathogen - hypothetical protein FTH_0508 1 None None None 115314883 Common - hypothetical protein FTH_1097 37 None None None 115315486 Common glnA glutamate--ammonia ligase FTH_1821 86 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 115314352 Common glmU UDP-N-acetylglucosamine diphosphorylase FTH_0450 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 115314016 Pathogen pyrD dihydroorotate oxidase FTH_0046 1 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 115315172 Common - fructokinase FTH_1446 113 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 115314538 Common recB exodeoxyribonuclease V FTH_0672 175 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 115314185 Common rpsH 30S ribosomal protein S8 FTH_0245 221 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 115314213 Pathogen - hypothetical protein FTH_0286 1 None None None 115314126 Common cydB cytochrome d ubiquinol oxidase subunit II FTH_0183 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 115314325 Common topA DNA topoisomerase I FTH_0419 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 115314187 Common rplR 50S ribosomal protein L18 FTH_0247 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 115314965 Pathogen - hypothetical protein FTH_1190 1 None None None 115314510 Common - hypothetical protein FTH_0641 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 115314555 Common caiC long-chain-fatty-acid--CoA ligase FTH_0692 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 115314892 Common suhB inositol-phosphate phosphatase FTH_1107 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 115314503 Common - probable methyltransferase FTH_0631 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 115314899 Common fabD [acyl-carrier-protein] S-malonyltransferase FTH_1115 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 115315351 Common hemA glutamyl-tRNA reductase FTH_1661 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 115314436 Common waaA KDO transferase (inner core) FTH_0549 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 115315177 Common cydC cysteine/glutathione ABC transporter membrane/ATP-binding component FTH_1451 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 115314594 Common - hypothetical protein FTH_0733 30 COG1738 COG1738, Uncharacterized conserved protein Function unknown 115315170 Common gpmI phosphoglyceromutase FTH_1444 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 115314515 Pathogen - hypothetical protein FTH_0647 1 None None None 115314910 Common iglB1 intracellular growth locus B protein FTH_1130 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 115315146 Common rplU 50S ribosomal protein L21 FTH_1415 161 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 115314576 Common mesJ probable PP-loop superfamily ATPase FTH_0715 211 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 115314096 Common isftu1 ISFtu1 transposase FTH_0146 58 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314900 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase FTH_1116 211 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 115315521 Common - MFS family major facilitator transporter FTH_1865 139 None None None 115315256 Common ansB asparaginase FTH_1546 132 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 115314013 Pathogen - probable chorismate mutase FTH_0043 2 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 115314396 Common pyrE orotate phosphoribosyltransferase FTH_0504 138 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 115314056 Pathogen - hypothetical protein FTH_0097 1 None None None 115314344 Common - M50 family peptidase FTH_0442 76 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 115314637 Common adk adenylate kinase FTH_0788 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 115315043 Common accD acetyl-CoA carboxylase beta subunit FTH_1281 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 115314830 Common dacB serine-type D-Ala-D-Ala carboxypeptidase FTH_1025 108 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 115315465 Common purL phosphoribosylformylglycinamidine synthase FTH_1789 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 115315035 Pathogen - hypothetical protein FTH_1272 1 None None None 115314586 Common - hypothetical protein FTH_0725 6 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 115314180 Common rpsQ 30S ribosomal protein S17 FTH_0240 224 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 115315429 Common nusA transcription elongation factor NusA FTH_1747 216 COG0195 NusA, Transcription elongation factor Transcription 115314209 Common - HAAAP family hydroxy/aromatic amino acid permease FTH_0282 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 115314115 Common rnpA ribonuclease P FTH_0170 17 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 115314698 Common - apolipoprotein N-acyltransferase FTH_0868 174 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 115314361 Common parC DNA topoisomerase IV subunit A FTH_0459 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 115314615 Common - possible PP-loop superfamily ATPase FTH_0761 157 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 115314548 Common potA polyamine ABC superfamily ATP binding cassette transporter, binding protein FTH_0683 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 115314139 Common - hypothetical protein FTH_0196 88 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 115314426 Common lpxD2 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase FTH_0539 178 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 115315528 Common msrA2 protein-methionine-S-oxide reductase FTH_1877 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 115314386 Common malQ 4-alpha-glucanotransferase FTH_0486 113 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 115314384 Common glgA glycogen synthase FTH_0484 134 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 115315008 Pathogen folB possible dihydroneopterin aldolase FTH_1239 3 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 115314907 Common pykA pyruvate kinase FTH_1123 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 115315077 Common - probable transcriptional regulator FTH_1329 102 COG1414 IclR, Transcriptional regulator Transcription 115314973 Pathogen - hypothetical protein FTH_1199 1 None None None 115314332 Common lspA signal peptidase II FTH_0427 179 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 115314985 Common - hypothetical protein FTH_1212 42 COG2431 COG2431, Predicted membrane protein Function unknown 115314543 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase FTH_0677 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 115314763 Pathogen - hypothetical protein FTH_0946 1 None None None 115314372 Common lolC lipoprotein ABC superfamily ATP binding cassette transporter, ABC protein FTH_0472 180 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 115314483 Common - glucose-1-phosphate thymidylyltransferase FTH_0605 231 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 115314314 Common murB UDP-N-acetylmuramate dehydrogenase FTH_0405 206 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 115314739 Common - probable metal-dependent hydrolase FTH_0916 12 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 115314710 Common - hypothetical protein FTH_0881 87 None None None 115314153 Common - probable MutT/nudix hydrolase FTH_0211 77 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 115314779 Common grxA glutaredoxin FTH_0964 57 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 115314732 Common - hypothetical protein FTH_0908 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 115314864 Common - probable thioredoxin family protein FTH_1071 61 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 115314651 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase FTH_0802 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 115314064 Pathogen pdpC2 conserved protein PdpC FTH_0108 1 None None None 115314624 Common - hypothetical protein FTH_0770 4 None None None 115314649 Common - APC family amino acid-polyamine-organocation transporter FTH_0800 76 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 115315348 Common - hypothetical protein FTH_1658 160 COG1576 COG1576, Uncharacterized conserved protein Function unknown 115314033 Common lepA GTP-binding protein LepA FTH_0067 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 115314131 Common cyoC cytochrome o ubiquinol oxidase subunit III FTH_0188 156 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 115315213 Common mutM DNA-formamidopyrimidine glycosylase FTH_1493 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 115314297 Common - methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase FTH_0386 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 115314020 Common isftu1 ISFtu1 transposase FTH_0052 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314235 Common aceE pyruvate dehydrogenase subunit E1 FTH_0310 135 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 115314043 Common - hypothetical protein FTH_0081 31 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 115315519 Common isftu1 ISFtu1 transposase FTH_1862 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314079 Common isftu1 ISFtu1 transposase FTH_0126 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 115314178 Common rplP 50S ribosomal protein L16 FTH_0238 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 115314995 Common - possible kinase FTH_1223 14 COG0645 COG0645, Predicted kinase General function prediction only 115315288 Pathogen - hypothetical protein FTH_1586 1 None None None 115315326 Pathogen - hypothetical protein FTH_1633 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 115315502 Common - acetyltransferase FTH_1838 29 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 115314751 Common - translation-associated GTPase FTH_0933 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 115314803 Pathogen - hypothetical protein FTH_0994 1 None None None 115314676 Common secF preprotein translocase subunit SecF FTH_0838 216 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 115314339 Common - MFS family major facilitator transporter FTH_0436 209 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 115314270 Common rph tRNA nucleotidyltransferase FTH_0352 187 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 115315295 Pathogen - hypothetical protein FTH_1599 1 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 115314467 Common - isocitrate dehydrogenase (NADP(+)) FTH_0588 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 115314081 Common - ribonuclease II FTH_0130 183 COG0557 VacB, Exoribonuclease R Transcription 115314754 Common - possible thiol:disulfide interchange protein FTH_0936 16 None None None 115315378 Common rplK 50S ribosomal protein L11 FTH_1688 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 115315028 Common - hypothetical protein FTH_1263 6 None None None 115314248 Common - chorismate mutase FTH_0326 39 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 115314645 Pathogen - hypothetical protein FTH_0796 1 None None None 115314562 Common - ABC superfamily ATP binding cassette transporter, ABC protein FTH_0699 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 115314284 Common - chorismate synthase FTH_0370 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 115314848 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein FTH_1046 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 115314550 Common nadE NAD(+) synthase (glutamine-hydrolyzing) FTH_0687 224 COG0171 NadE, NAD synthase Coenzyme metabolism