Rhodococcus sp. RHA1 plasmid pRHL3, complete sequence NC_008271 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 111027153 Common - chlorite dismutase RHA1_ro11326 35 COG3253 COG3253, Uncharacterized conserved protein Function unknown 111026830 Nonpathogen - hypothetical protein RHA1_ro11003 2 None None None 111027100 Nonpathogen - hypothetical protein RHA1_ro11273 1 None None None 111026893 Common - possible transposase RHA1_ro11066 9 None None None 111026957 Nonpathogen - hypothetical protein RHA1_ro11130 1 None None None 111027006 Common - probable glutaconate CoA-transferase RHA1_ro11179 41 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 111026917 Nonpathogen - hypothetical protein RHA1_ro11090 1 None None None 111027085 Nonpathogen - hypothetical protein RHA1_ro11258 1 None None None 111027080 Nonpathogen - hypothetical protein RHA1_ro11253 1 None None None 111027113 Nonpathogen - hypothetical protein RHA1_ro11286 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 111027022 Nonpathogen - hypothetical protein RHA1_ro11195 1 None None None 111027055 Common - possible NADH dehydrogenase RHA1_ro11228 44 COG2210 COG2210, Uncharacterized conserved protein Function unknown 111026988 Common - hypothetical protein RHA1_ro11161 28 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 111027071 Nonpathogen - hypothetical protein RHA1_ro11244 1 None None None 111027127 Nonpathogen - hypothetical protein RHA1_ro11300 1 None None None 111027033 Common - Cu(2+)-exporting ATPase RHA1_ro11206 23 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 111026886 Nonpathogen - hypothetical protein RHA1_ro11059 2 None None None 111027133 Common pknK2 serine/threonine protein kinase RHA1_ro11306 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 111026946 Common - probable transposase RHA1_ro11119 50 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 111026920 Nonpathogen - hypothetical protein RHA1_ro11093 1 None None None 111027000 Common - multidrug resistance transporter, MFS superfamily RHA1_ro11173 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 111027143 Common - malate dehydrogenase (oxaloacetate-decarboxylating) RHA1_ro11316 199 COG0281 SfcA, Malic enzyme Energy production and conversion 111026856 Common sucB dihydrolipoyllysine-residue succinyltransferase RHA1_ro11029 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 111027040 Common - probable copper resistance transporter, ATPase component RHA1_ro11213 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 111027106 Nonpathogen - hypothetical protein RHA1_ro11279 1 None None None 111027089 Nonpathogen - hypothetical protein RHA1_ro11262 1 None None None 111027025 Common - possible 3-demethylubiquinone-9 3-methyltransferase RHA1_ro11198 15 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 111027016 Nonpathogen - hypothetical protein RHA1_ro11189 1 None None None 111027090 Common - possible ATPase, ParA type RHA1_ro11263 214 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 111027046 Common - possible hydrolase RHA1_ro11219 171 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 111026960 Nonpathogen - hypothetical protein RHA1_ro11133 1 None None None 111026906 Nonpathogen - hypothetical protein RHA1_ro11079 2 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 111027156 Common - 3-hexulose-6-phosphate synthase RHA1_ro11329 57 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 111026873 Common limB limonene 1,2-monooxygenase (NADH-dependent) RHA1_ro11046 68 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 111027125 Nonpathogen - probable N-formylglutamate amidohydrolase RHA1_ro11298 13 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 111027144 Common - possible transcriptional regulator, AraC family RHA1_ro11317 84 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 111026865 Common - possible integrase RHA1_ro11038 2 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 111027066 Common - hypothetical protein RHA1_ro11239 68 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 111026963 Nonpathogen - hypothetical protein RHA1_ro11136 1 None None None 111026910 Nonpathogen - hypothetical protein RHA1_ro11083 1 None None None 111027062 Common - possible carboxymuconolactone decarboxylase RHA1_ro11235 79 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 111026925 Common - ABC transporter, ATP-binding component RHA1_ro11098 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 111027146 Common - probable oxidoreductase RHA1_ro11319 121 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 111027057 Common - hypothetical protein RHA1_ro11230 19 COG2149 COG2149, Predicted membrane protein Function unknown 111027078 Nonpathogen - hypothetical protein RHA1_ro11251 1 None None None 111026974 Common - ATP-dependent DNA ligase RHA1_ro11147 111 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 111026864 Nonpathogen - hypothetical protein RHA1_ro11037 2 None None None 111027115 Common - hypothetical protein RHA1_ro11288 9 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 111026860 Common - transcriptional regulator, TetR family RHA1_ro11033 70 COG1309 AcrR, Transcriptional regulator Transcription 111026903 Common - hypothetical protein RHA1_ro11076 29 None None None 111027104 Common - cytochrome P450 CYP258 RHA1_ro11277 64 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 111027036 Common - hypothetical protein RHA1_ro11209 2 None None None 111026955 Common - possible carbonic anhydrase RHA1_ro11128 29 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 111026888 Common gnd4 6-phosphogluconate dehydrogenase-like protein RHA1_ro11061 182 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 111026929 Common - probable protein kinase RHA1_ro11102 157 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 111026944 Common - hypothetical protein RHA1_ro11117 2 None None None 111027116 Nonpathogen - hypothetical protein RHA1_ro11289 3 None None None 111026986 Common - probable AMP-binding acyl-CoA synthetase RHA1_ro11159 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 111027002 Common - ABC sugar transporter, ATP-binding component RHA1_ro11175 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 111027094 Common - probable replication protein RHA1_ro11267 3 None None None 111027027 Nonpathogen - hypothetical protein RHA1_ro11200 1 None None None 111026938 Common - possible excisionase RHA1_ro11111 25 None None None 111027019 Nonpathogen - hypothetical protein RHA1_ro11192 1 None None None 111026849 Common - fatty-acid--CoA ligase RHA1_ro11022 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 111026901 Nonpathogen - hypothetical protein RHA1_ro11074 1 None None None 111026919 Nonpathogen - hypothetical protein RHA1_ro11092 1 None None None 111027052 Common - hypothetical protein RHA1_ro11225 168 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 111026908 Nonpathogen - hypothetical protein RHA1_ro11081 1 None None None 111027064 Common - possible sulfurtransferase, rhodanese related RHA1_ro11237 28 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 111026869 Nonpathogen - hypothetical protein RHA1_ro11042 1 None None None 111027092 Common - hypothetical protein RHA1_ro11265 3 None None None 111026838 Nonpathogen - hypothetical protein RHA1_ro11011 2 None None None 111027044 Common - hypothetical protein RHA1_ro11217 2 None None None 111027083 Nonpathogen - hypothetical protein RHA1_ro11256 2 None None None 111026891 Common - possible transcriptional regulator, WhiB family RHA1_ro11064 19 None None None 111026931 Nonpathogen - hypothetical protein RHA1_ro11104 1 None None None 111027009 Common - enoyl-CoA hydratase RHA1_ro11182 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 111027060 Common - possible hydrolase RHA1_ro11233 198 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 111027158 Common - probable transcriptional regulator, LuxR family RHA1_ro11331 96 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 111026976 Nonpathogen - hypothetical protein RHA1_ro11149 1 None None None 111027139 Common - probable flavin reductase like domain RHA1_ro11312 109 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 111026965 Nonpathogen - hypothetical protein RHA1_ro11138 1 None None None 111026842 Nonpathogen - hypothetical protein RHA1_ro11015 1 None None None 111027039 Common - probable copper ion binding protein RHA1_ro11212 99 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 111026832 Nonpathogen - hypothetical protein RHA1_ro11005 2 None None None 111026993 Common - probable glucose-6-phosphate 1-dehydrogenase RHA1_ro11166 78 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 111027130 Nonpathogen - hypothetical protein RHA1_ro11303 1 None None None 111026999 Nonpathogen - hypothetical protein RHA1_ro11172 1 None None None 111027010 Common - acyl-CoA dehydrogenase RHA1_ro11183 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 111026852 Common - hypothetical protein RHA1_ro11025 2 None None None 111026972 Common - hypothetical protein RHA1_ro11145 7 None None None 111026952 Nonpathogen - hypothetical protein RHA1_ro11125 1 None None None 111026904 Common - probable AAA ATPase RHA1_ro11077 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 111026881 Common - probable transcriptional regulator RHA1_ro11054 138 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 111027076 Nonpathogen - hypothetical protein RHA1_ro11249 1 None None None 111027103 Nonpathogen - hypothetical protein RHA1_ro11276 1 None None None 111027097 Nonpathogen - hypothetical protein RHA1_ro11270 1 None None None 111027082 Nonpathogen - hypothetical protein RHA1_ro11255 1 None None None 111026923 Common - hypothetical protein RHA1_ro11096 3 None None None 111027138 Nonpathogen - hypothetical protein RHA1_ro11311 3 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 111026964 Nonpathogen - hypothetical protein RHA1_ro11137 1 None None None 111027122 Common - hypothetical protein RHA1_ro11295 2 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 111026841 Nonpathogen - hypothetical protein RHA1_ro11014 6 None None None 111026828 Nonpathogen - hypothetical protein RHA1_ro11001 1 None None None 111026854 Common - possible transposase RHA1_ro11027 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 111027136 Common macA maleylacetate reductase RHA1_ro11309 156 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 111026975 Common - hypothetical protein RHA1_ro11148 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 111027152 Nonpathogen - hypothetical protein RHA1_ro11325 1 None None None 111026928 Common - possible transcriptional regulator, MarR family RHA1_ro11101 49 COG1846 MarR, Transcriptional regulators Transcription 111026912 Nonpathogen - hypothetical protein RHA1_ro11085 1 None None None 111026878 Common - possible transposase RHA1_ro11051 5 None None None 111027148 Common - possible ethyl tert-butyl ether degradation protein RHA1_ro11321 11 None None None 111026967 Common - hypothetical protein RHA1_ro11140 4 None None None 111026991 Common - possible hybride transferase/ F420-dependent dehydrogenase RHA1_ro11164 126 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 111027037 Common - probable copper-exporting ATPase RHA1_ro11210 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 111026997 Common adhB alcohol dehydrogenase RHA1_ro11170 182 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 111027093 Nonpathogen - hypothetical protein RHA1_ro11266 1 None None None 111027029 Common - hypothetical protein RHA1_ro11202 7 COG3462 COG3462, Predicted membrane protein Function unknown 111026898 Common - 3-hydroxyacyl-CoA dehydrogenase RHA1_ro11071 159 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 111026902 Nonpathogen - hypothetical protein RHA1_ro11075 2 None None None 111026984 Common - possible transposase, C-terminal RHA1_ro11157 7 None None None 111026934 Common - possible transposase RHA1_ro11107 16 None None None 111026979 Common hsdS type I restriction-modification system specificity subunit RHA1_ro11152 97 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 111027050 Common - possible forkhead associated domain (FHA) RHA1_ro11223 49 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 111027108 Common - hypothetical protein RHA1_ro11281 6 COG0583 LysR, Transcriptional regulator Transcription 111027058 Nonpathogen - hypothetical protein RHA1_ro11231 1 COG2149 COG2149, Predicted membrane protein Function unknown 111027110 Common - possible transposase RHA1_ro11283 45 None None None 111026850 Common fabG2 3-oxoacyl-[acyl-carrier-protein] reductase FabG RHA1_ro11023 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 111026982 Common - probable transposase RHA1_ro11155 43 None None None 111026843 Nonpathogen - hypothetical protein RHA1_ro11016 2 None None None 111027119 Common - possible DNA translocase RHA1_ro11292 115 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 111026950 Nonpathogen - hypothetical protein RHA1_ro11123 1 COG2135 COG2135, Uncharacterized conserved protein Function unknown 111026959 Nonpathogen - hypothetical protein RHA1_ro11132 1 None None None 111026839 Common - probable phosphoadenylyl-sulfate reductase (thioredoxin) RHA1_ro11012 75 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 111026936 Nonpathogen - hypothetical protein RHA1_ro11109 1 None None None 111026833 Nonpathogen - hypothetical protein RHA1_ro11006 1 None None None 111027135 Common - hypothetical protein RHA1_ro11308 3 None None None 111026846 Common - possible transcriptional regulator RHA1_ro11019 83 COG1522 Lrp, Transcriptional regulators Transcription 111027141 Common - possible transcriptional regulator, AraC family RHA1_ro11314 43 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 111026981 Common - hypothetical protein RHA1_ro11154 22 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 111026914 Nonpathogen - hypothetical protein RHA1_ro11087 1 None None None 111026858 Common - probable pyruvate dehydrogenase RHA1_ro11031 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 111026883 Common aldH2 aldehyde dehydrogenase RHA1_ro11056 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 111027015 Common - probable synthetase/ligase RHA1_ro11188 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 111027068 Common - hypothetical protein RHA1_ro11241 41 COG3439 COG3439, Uncharacterized conserved protein Function unknown 111027129 Common - possible ATP-dependent helicase RHA1_ro11302 93 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 111027099 Common - transposase RHA1_ro11272 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 111027101 Common - possible repressor protein, helix-turn-helix family RHA1_ro11274 13 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 111027120 Nonpathogen - hypothetical protein RHA1_ro11293 1 None None None 111027074 Common - probable Zn-dependent oxidoreductase RHA1_ro11247 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 111026970 Common - possible transposase RHA1_ro11143 6 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 111027004 Common - aldehyde dehydrogenase RHA1_ro11177 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 111026969 Common - hypothetical protein RHA1_ro11142 3 None None None 111026941 Common - hypothetical protein RHA1_ro11114 6 None None None 111027159 Common zwf5 glucose-6-phosphate 1-dehydrogenase RHA1_ro11332 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 111026867 Common - hypothetical protein RHA1_ro11040 16 COG1920 COG1920, Uncharacterized conserved protein Function unknown 111027154 Common pgi glucose-6-phosphate isomerase RHA1_ro11327 204 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 111026956 Common - possible transcriptional regulator RHA1_ro11129 5 None None None 111026829 Nonpathogen - hypothetical protein RHA1_ro11002 2 None None None 111027095 Nonpathogen - hypothetical protein RHA1_ro11268 2 None None None 111027035 Common - hypothetical protein RHA1_ro11208 101 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 111026916 Nonpathogen - hypothetical protein RHA1_ro11089 1 None None None 111026948 Nonpathogen - hypothetical protein RHA1_ro11121 1 None None None 111027020 Common - possible resolvase, N-terminal RHA1_ro11193 116 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 111026848 Nonpathogen - hypothetical protein RHA1_ro11021 1 None None None 111027048 Nonpathogen - hypothetical protein RHA1_ro11221 1 None None None 111026995 Common - acyl-CoA synthetase RHA1_ro11168 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 111027012 Common - probable acetyl-CoA C-acyltransferase (3-ketoacyl-CoA thiolase) RHA1_ro11185 131 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 111026926 Nonpathogen - hypothetical protein RHA1_ro11099 1 None None None 111027087 Nonpathogen - hypothetical protein RHA1_ro11260 1 None None None 111026871 Common limC3 dichlorophenolindophenol-dependent carveol dehydrogenase RHA1_ro11044 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 111027107 Nonpathogen - hypothetical protein RHA1_ro11280 1 None None None 111026930 Common - hypothetical protein RHA1_ro11103 2 None None None 111026880 Common - possible N-acyl homoserine lactonase RHA1_ro11053 71 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 111026961 Common - hypothetical protein RHA1_ro11134 2 None None None 111026837 Nonpathogen - hypothetical protein RHA1_ro11010 2 None None None 111026863 Common - possible 3-oxoacyl-(acyl-carrier-protein) reductase RHA1_ro11036 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 111027047 Common - possible transcriptional regulator, ArsR family RHA1_ro11220 92 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 111026968 Nonpathogen - hypothetical protein RHA1_ro11141 1 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 111027024 Common - possible transcriptional regulator RHA1_ro11197 30 COG1309 AcrR, Transcriptional regulator Transcription 111026940 Nonpathogen - hypothetical protein RHA1_ro11113 1 None None None 111026896 Common - cytochrome P450 CYP257 RHA1_ro11069 66 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 111027067 Common - hypothetical protein RHA1_ro11240 36 None None None 111026992 Common - possible hydrolase RHA1_ro11165 68 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 111027063 Nonpathogen - hypothetical protein RHA1_ro11236 1 None None None 111026835 Nonpathogen - hypothetical protein RHA1_ro11008 2 None None None 111026909 Nonpathogen - hypothetical protein RHA1_ro11082 1 None None None 111026866 Common - possible transposase RHA1_ro11039 4 None None None 111026847 Common - probable lysine exporter protein, LysE family RHA1_ro11020 9 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 111026874 Common - possible oxidoreductase RHA1_ro11047 97 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 111026879 Common - hypothetical protein RHA1_ro11052 11 None None None 111027038 Nonpathogen - hypothetical protein RHA1_ro11211 1 None None None 111027145 Nonpathogen - hypothetical protein RHA1_ro11318 1 None None None 111027088 Common - possible mycobacteriophage excisionase RHA1_ro11261 3 None None None 111027043 Nonpathogen - hypothetical protein RHA1_ro11216 1 None None None 111026894 Common - probable ferredoxin--NAD(+) reductase RHA1_ro11067 244 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 111027007 Common - probable 3-oxoacyl-[acyl-carrier-protein] reductase RHA1_ro11180 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 111026945 Nonpathogen - hypothetical protein RHA1_ro11118 1 None None None 111027126 Common - hypothetical protein RHA1_ro11299 3 None None None 111026980 Common hsdR type I site-specific modification system restriction subunit RHA1_ro11153 124 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 111027079 Nonpathogen - hypothetical protein RHA1_ro11252 4 None None None 111027030 Common - response regulator, two-component system RHA1_ro11203 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 111026885 Common - protein kinase/ transcriptional regulator, LuxR family RHA1_ro11058 155 COG3903 COG3903, Predicted ATPase General function prediction only 111026921 Common - possible transposase (mutator type) RHA1_ro11094 42 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 111026954 Common - hypothetical protein RHA1_ro11127 3 None None None 111027001 Common - ABC sugar transporter, permease component RHA1_ro11174 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 111026971 Common - probable integrase/recombinase, XerC and XerD family RHA1_ro11144 154 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 111026840 Common - hypothetical protein RHA1_ro11013 64 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 111026998 Common - hypothetical protein RHA1_ro11171 115 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 111026855 Common - Zn-dependent alcohol dehydrogenase RHA1_ro11028 196 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 111026989 Common fabG3 3-oxoacyl-[acyl-carrier-protein] reductase RHA1_ro11162 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 111027132 Nonpathogen - hypothetical protein RHA1_ro11305 1 None None None 111027114 Nonpathogen - hypothetical protein RHA1_ro11287 3 None None None 111027045 Common - probable transporter, MFS superfamily RHA1_ro11218 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 111026861 Common - possible regulator of polyketide synthase expression RHA1_ro11034 25 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 111026918 Common - hypothetical protein RHA1_ro11091 40 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 111027026 Common - hypothetical protein RHA1_ro11199 4 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 111027091 Nonpathogen - hypothetical protein RHA1_ro11264 1 None None None 111026887 Common - transcriptional regulator, DeoR family RHA1_ro11060 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 111026990 Common - hypothetical protein RHA1_ro11163 2 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 111027008 Common menB naphthoate synthase RHA1_ro11181 180 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 111027053 Common - probable polysulphide reductase RHA1_ro11226 166 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 111026939 Nonpathogen - hypothetical protein RHA1_ro11112 1 None None None 111027084 Nonpathogen - hypothetical protein RHA1_ro11257 1 None None None 111026899 Nonpathogen - hypothetical protein RHA1_ro11072 1 None None None 111026876 Common - probable transposase RHA1_ro11049 5 None None None 111027054 Common - hypothetical protein RHA1_ro11227 80 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 111026831 Nonpathogen - hypothetical protein RHA1_ro11004 3 None None None 111027077 Nonpathogen - hypothetical protein RHA1_ro11250 1 None None None 111027155 Common gnd5 6-phosphogluconate dehydrogenase-like protein RHA1_ro11328 183 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 111026900 Nonpathogen - hypothetical protein RHA1_ro11073 1 None None None 111027131 Common - hypothetical protein RHA1_ro11304 3 None None None 111026932 Nonpathogen - hypothetical protein RHA1_ro11105 1 None None None 111027065 Common - probable membrane transport protein RHA1_ro11238 26 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 111027017 Common - acetyl-CoA synthetase RHA1_ro11190 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 111026851 Common lpdA dihydrolipoyl dehydrogenanse RHA1_ro11024 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 111027061 Common - probable thioredoxin RHA1_ro11234 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 111026996 Common - carveol dehydrogenase RHA1_ro11169 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 111026882 Nonpathogen - hypothetical protein RHA1_ro11055 1 None None None 111027032 Common - hypothetical protein RHA1_ro11205 6 None None None 111026962 Common - hypothetical protein RHA1_ro11135 12 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 111027124 Common - hypothetical protein RHA1_ro11297 4 None None None 111027041 Common - hypothetical protein RHA1_ro11214 4 None None None 111027072 Common - probable sulfate transporter RHA1_ro11245 55 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 111027147 Common - cytochrome P450 CYP116 RHA1_ro11320 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 111027160 Common - possible phosphate transport system protein PhoU RHA1_ro11333 18 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 111026977 Nonpathogen - hypothetical protein RHA1_ro11150 1 None None None 111027086 Nonpathogen - hypothetical protein RHA1_ro11259 1 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 111026943 Common - probable transposase RHA1_ro11116 79 None None None 111027123 Common - hypothetical protein RHA1_ro11296 2 None None None 111027150 Nonpathogen - hypothetical protein RHA1_ro11323 2 None None None 111027105 Common - hypothetical protein RHA1_ro11278 9 None None None 111026987 Common - hypothetical protein RHA1_ro11160 2 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 111027003 Nonpathogen - ABC sugar transporter, periplasmic substrate binding protein RHA1_ro11176 4 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 111026853 Common - possible transposase RHA1_ro11026 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 111027117 Nonpathogen - hypothetical protein RHA1_ro11290 1 None None None 111026942 Common - possible general secretion pathway protein RHA1_ro11115 62 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 111026892 Nonpathogen - hypothetical protein RHA1_ro11065 1 None None None 111027137 Common - hydroxyquinol 1,2-dioxygenase RHA1_ro11310 49 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 111027018 Nonpathogen - hypothetical protein RHA1_ro11191 1 None None None 111026994 Common pgi glucose-6-phosphate isomerase RHA1_ro11167 201 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 111027098 Nonpathogen - hypothetical protein RHA1_ro11271 1 None None None 111027034 Common - hypothetical protein RHA1_ro11207 36 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 111026870 Nonpathogen - hypothetical protein RHA1_ro11043 1 None None None 111026875 Common - 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase II RHA1_ro11048 222 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 111026911 Nonpathogen - hypothetical protein RHA1_ro11084 1 None None None 111027070 Common - hypothetical protein RHA1_ro11243 192 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 111026897 Nonpathogen - hypothetical protein RHA1_ro11070 1 None None None 111026927 Common - probable serine/threonine protein kinase RHA1_ro11100 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 111026953 Nonpathogen - hypothetical protein RHA1_ro11126 1 None None None 111027096 Nonpathogen - hypothetical protein RHA1_ro11269 1 None None None 111027051 Common - possible ATPase RHA1_ro11224 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 111026978 Common hsdM type I restriction-modification system methyltransferase subunit RHA1_ro11151 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 111027011 Common - hypothetical protein RHA1_ro11184 22 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 111027021 Nonpathogen - hypothetical protein RHA1_ro11194 1 None None None 111027028 Common - possible copper-binding oxidase RHA1_ro11201 124 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 111026935 Common - probable 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase RHA1_ro11108 192 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 111026844 Common - hypothetical protein RHA1_ro11017 11 None None None 111026889 Common - possible F420-dependent glucose-6-phosphate dehydrogenase RHA1_ro11062 72 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 111026985 Common - possible transcriptional regulator, WhiB family RHA1_ro11158 19 None None None 111026859 Common - possible isovaleryl-CoA dehydrogenase RHA1_ro11032 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 111026933 Nonpathogen - hypothetical protein RHA1_ro11106 1 None None None 111026924 Nonpathogen - hypothetical protein RHA1_ro11097 1 None None None 111027140 Common - possible indole oxygenase RHA1_ro11313 54 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 111026884 Nonpathogen - hypothetical protein RHA1_ro11057 2 None None None 111027157 Common - possible 6-phospho-3-hexuloisomerase RHA1_ro11330 101 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 111026862 Common - probable 3-hydroxybutyryl-CoA dehydratase RHA1_ro11035 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 111027118 Nonpathogen - hypothetical protein RHA1_ro11291 1 None None None 111026958 Nonpathogen - hypothetical protein RHA1_ro11131 1 None None None 111027056 Common - possible hydroxyacylglutathione hydrolase RHA1_ro11229 108 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 111026905 Common - possible acyl carrier protein RHA1_ro11078 16 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 111027081 Nonpathogen - hypothetical protein RHA1_ro11254 1 None None None 111026834 Nonpathogen - hypothetical protein RHA1_ro11007 1 None None None 111027075 Nonpathogen - hypothetical protein RHA1_ro11248 1 None None None 111027121 Common - hypothetical protein RHA1_ro11294 9 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 111026868 Common fbiC FO synthase RHA1_ro11041 85 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 111026872 Nonpathogen - hypothetical protein RHA1_ro11045 1 None None None 111026907 Nonpathogen - hypothetical protein RHA1_ro11080 1 None None None 111026877 Nonpathogen - hypothetical protein RHA1_ro11050 2 None None None 111026890 Common pgi glucose-6-phosphate isomerase RHA1_ro11063 200 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 111027151 Nonpathogen - hypothetical protein RHA1_ro11324 1 None None None 111026915 Nonpathogen - hypothetical protein RHA1_ro11088 1 None None None 111026949 Common - probable DNA ligase RHA1_ro11122 81 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 111027069 Common - possible permease RHA1_ro11242 80 COG0730 COG0730, Predicted permeases General function prediction only 111027149 Nonpathogen - hypothetical protein RHA1_ro11322 1 None None None 111027042 Common - ABC transporter, ATP-binding component RHA1_ro11215 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 111026845 Nonpathogen - hypothetical protein RHA1_ro11018 1 None None None 111027049 Nonpathogen - hypothetical protein RHA1_ro11222 1 None None None 111026913 Common - possible lysyl tRNA synthetase-like protein RHA1_ro11086 17 None None None 111027023 Common - possible ATP-binding protease, Clp family RHA1_ro11196 83 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 111026937 Common - hypothetical protein RHA1_ro11110 2 None None None 111027013 Common - possible transcriptional regulator, GntR family RHA1_ro11186 123 COG1802 GntR, Transcriptional regulators Transcription 111026966 Nonpathogen - hypothetical protein RHA1_ro11139 1 None None None 111027031 Common - histidine kinase RHA1_ro11204 218 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 111027161 Common - probable ATP-dependent Clp protease ATP-binding subunit RHA1_ro11334 38 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 111027109 Common - possible ATP/GTP-binding protein RHA1_ro11282 16 None None None 111026951 Common - probable transposase RHA1_ro11124 46 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 111027059 Common - probable transcriptional regulator, ArsR family RHA1_ro11232 157 COG0640 ArsR, Predicted transcriptional regulators Transcription 111026983 Common - possible transposase, N-terminal RHA1_ro11156 85 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 111026857 Common - probable pyruvate dehydrogenase RHA1_ro11030 215 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 111027134 Common - probable 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase II RHA1_ro11307 169 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 111026922 Common - probable transcriptional regulator RHA1_ro11095 39 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 111027111 Nonpathogen - hypothetical protein RHA1_ro11284 5 None None None 111027112 Common - probable peptidase RHA1_ro11285 196 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 111027014 Common - possible fatty acid-CoA racemase RHA1_ro11187 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 111027142 Common - possible transcriptional regulator, WhiB family RHA1_ro11315 19 None None None 111027005 Common - hypothetical protein RHA1_ro11178 43 COG1309 AcrR, Transcriptional regulator Transcription 111026836 Nonpathogen - hypothetical protein RHA1_ro11009 2 None None None 111027073 Nonpathogen - hypothetical protein RHA1_ro11246 1 None None None 111027128 Common - possible ATP-dependent helicase RHA1_ro11301 22 None None None 111026895 Common - probable ferredoxin (ThcC) RHA1_ro11068 60 COG0633 Fdx, Ferredoxin Energy production and conversion 111026973 Nonpathogen - hypothetical protein RHA1_ro11146 1 None None None 111026947 Nonpathogen - hypothetical protein RHA1_ro11120 1 None None None 111027102 Common - possible intracellular septation protein RHA1_ro11275 85 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning