Clostridium perfringens SM101, complete genome NC_008262 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 110801698 Common fhuC ferrichrome ABC transporter CPR_0214 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110801883 Common pgi glucose-6-phosphate isomerase CPR_2252 206 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 110803227 Common topB DNA topoisomerase III CPR_1489 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110802151 Common - peptidase, M23/M37 family CPR_2621 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110802822 Common - transcriptional regulator, GntR family/aminotransferase CPR_1924 212 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110802259 Common aroK shikimate kinase CPR_0694 202 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 110801506 Common - cytidine/deoxycytidylate deaminase family protein CPR_1134 92 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 110803493 Common - hypothetical protein CPR_1769 32 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110803499 Pathogen - probable thioredoxin CPR_1567 1 None None None 110803889 Common - hypothetical protein CPR_1441 1 None None None 110802252 Pathogen - hypothetical protein CPR_1471 2 None None None 110802350 Common - ISCpe5, transposase CPR_0187 39 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802914 Common - NUDIX domain protein CPR_0661 10 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110803735 Common modA molybdenum ABC transporter, periplasmic molybdate-binding protein CPR_2054 162 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 110803661 Common - teichoic acid translocation permease protein CPR_0254 76 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110802435 Common rpoA DNA-directed RNA polymerase subunit alpha CPR_2370 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 110802180 Common - hypothetical protein CPR_0925 4 COG3382 COG3382, Uncharacterized conserved protein Function unknown 110801814 Common - sodium:dicarboxylate symporter family protein CPR_1019 164 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 110803102 Common secA preprotein translocase subunit SecA CPR_2139 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 110803583 Common - hypothetical protein CPR_0643 1 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 110803231 Pathogen - hypothetical protein CPR_0638 1 None None None 110802047 Common era GTP-binding protein Era CPR_1987 232 COG1159 Era, GTPase General function prediction only 110803080 Common noxA nitrate reductase, NADH oxidase subunit CPR_1765 222 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110802982 Common - transposase, putative CPR_0197 1 None None None 110802107 Common - tldD protein truncated CPR_0325 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 110802908 Common - radical SAM enzyme, Cfr family CPR_1711 195 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 110802496 Common - phnA family protein CPR_2595 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 110803546 Common - hypothetical protein CPR_1261 12 None None None 110802424 Common - PDZ domain protein CPR_2495 217 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110802809 Common - uncharacterized conserved membrane protein, YYAD CPR_2565 21 COG3949 COG3949, Uncharacterized membrane protein Function unknown 110803986 Common rplT 50S ribosomal protein L20 CPR_1856 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 110803424 Common - putative lipid kinase CPR_1328 102 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 110801878 Common - hypothetical protein CPR_0981 35 COG1289 COG1289, Predicted membrane protein Function unknown 110802833 Common pheT phenylalanyl-tRNA synthetase subunit beta CPR_1851 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 110802705 Common - hypothetical protein CPR_1973 33 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 110801865 Common - sensor histidine kinase CPR_1892 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110803065 Common - ISCpe7, transposase CPR_0929 6 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802306 Common - transcriptional regulator, MarR family CPR_0773 36 COG1846 MarR, Transcriptional regulators Transcription 110802062 Common xerD tyrosine recombinase XerD CPR_1777 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110803584 Common - hypothetical protein CPR_2619 9 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 110802973 Common - hypothetical protein CPR_1540 1 None None None 110801488 Common - hypothetical protein CPR_0056 64 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 110803323 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase CPR_1654 211 COG0196 RibF, FAD synthase Coenzyme metabolism 110803480 Common - transcriptional regulator, GntR family CPR_2646 139 COG2188 PhnF, Transcriptional regulators Transcription 110803626 Pathogen - hypothetical protein CPR_0744 1 None None None 110803719 Common - hypothetical protein CPR_1635 57 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 110803944 Common - LysE type translocator superfamily CPR_2660 38 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110801675 Common - DNA polymerase III, alpha subunit, interruption-C CPR_0340 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 110801880 Common - hypothetical protein CPR_1462 5 None None None 110803975 Common - MATE efflux family protein CPR_1463 126 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110803467 Common - hypothetical protein CPR_0351 4 None None None 110802901 Common tpiA triosephosphate isomerase CPR_1299 218 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 110803357 Common - MazG family protein CPR_2489 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 110802462 Common - stage II sprulation protein E, putative CPR_2475 31 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 110802416 Common - nitrite/sulfite reductase-like protein CPR_0512 156 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 110803489 Pathogen - hypothetical protein CPR_0943 1 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 110803259 Common - RNA polymerase sigma-70 factor CPR_0523 145 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110802829 Common - ribosomal large subunit pseudouridine synthase f CPR_0987 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110803207 Common - hypothetical protein CPR_0503 60 COG1971 COG1971, Predicted membrane protein Function unknown 110803574 Common - hypothetical protein CPR_1039 4 None None None 110802089 Common - hypothetical protein CPR_1849 22 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110803282 Common - hypothetical protein CPR_2445 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 110801913 Common - ferredoxin CPR_2520 40 COG1141 Fer, Ferredoxin Energy production and conversion 110803565 Common - pseudouridylate synthase CPR_1224 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110803473 Common - N-acetylmannosamine-6-phosphate 2-epimerase CPR_0174 45 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 110803896 Common - ISCpe5, transposase CPR_0766 11 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803416 Common - recombination factor protein RarA CPR_1757 242 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 110803503 Common - DNA topoisomerase IV subunit A CPR_2039 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110802559 Pathogen - hypothetical protein CPR_1244 1 None None None 110803444 Common - DedA family protein CPR_0866 153 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110803873 Common groES co-chaperonin GroES CPR_2276 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 110801904 Common - PP-loop family protein CPR_1059 172 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110802262 Pathogen - hypothetical protein CPR_2423 1 None None None 110802158 Common - Periplasmic binding protein family CPR_0794 69 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110801595 Common - mutS domain protein CPR_2123 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110801760 Common rnhB ribonuclease HII CPR_1678 222 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 110802039 Common rbsA ribose transport ATP-binding protein rbsA CPR_1601 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110802345 Common ackA acetate kinase CPR_0206 162 COG0282 ackA, Acetate kinase Energy production and conversion 110803678 Pathogen - hypothetical protein CPR_0861 1 None None None 110802732 Common - penicillin-binding protein dacf precursor CPR_1775 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110802793 Common - N-acetylmuramoyl-L-alanine amidase domain protein CPR_1483 18 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110803539 Common recQ ATP-dependent DNA helicase RecQ CPR_1335 217 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 110803386 Common dnaA chromosomal replication initiation protein CPR_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 110802790 Common - ribose ABC transporter protein CPR_1602 43 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 110803658 Common - putative metal-dependent hydrolase, membrane-bound CPR_1028 17 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 110803668 Pathogen - hypothetical protein CPR_1066 1 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 110801486 Common - sodium/alanine symporter CPR_1408 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 110803761 Common - transcriptional regulator CPR_0899 57 COG1476 COG1476, Predicted transcriptional regulators Transcription 110803795 Common - antibiotic ABC transporter ATP binding protein SSO1934 CPR_0764 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110803342 Common - ISCpe4, transposase CPR_0220 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801792 Pathogen - hypothetical protein CPR_0467 1 None None None 110802295 Common - CAAX amino terminal protease family protein CPR_0879 53 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 110802408 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CPR_1828 208 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 110801754 Common nanA N-acetylneuraminate lyase CPR_0175 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110801929 Common - hypothetical protein CPR_1821 52 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 110802322 Common gloA lactoylglutathione lyase CPR_0440 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110801456 Common - two-component response regulator CPR_2327 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110802343 Common tagA N-acetyl-mannosamine transferase CPR_0585 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 110801799 Common - oxidoreductase, pyridine nucleotide-disulphide family CPR_2205 196 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110803634 Common - glutaminase CPR_1963 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 110802926 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II CPR_1139 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110803107 Common - HesB-related (seleno)protein subfamily, putative CPR_0642 1 None None None 110801920 Common - glycosyltransferase CPR_2193 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110802816 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein CPR_2260 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 110802189 Common - transcriptional regulator, Fur family CPR_1746 200 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110803304 Common rplQ 50S ribosomal protein L17 CPR_2369 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 110801764 Pathogen - hypothetical protein CPR_0761 1 None None None 110802191 Common rplB 50S ribosomal protein L2 CPR_2396 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 110803671 Common - hypothetical protein CPR_1698 33 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 110802846 Common - hypothetical protein CPR_1520 10 None None None 110801738 Common - ISCpe7, transposase CPR_0802 52 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803881 Common rpsS 30S ribosomal protein S19 CPR_2395 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 110802588 Common - K+-dependent Na+/Ca+ exchanger related-protein CPR_1536 126 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 110802072 Pathogen - hypothetical protein CPR_0572 3 COG2456 COG2456, Uncharacterized conserved protein Function unknown 110801684 Common - hypothetical protein CPR_0284 1 None None None 110803599 Common - hypothetical protein CPR_1922 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 110803131 Common - sensor histidine kinase CPR_0449 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110802403 Common - spore germination protein, GerABKC family CPR_0616 12 None None None 110803939 Common - phosphate ABC transporter, permease protein CPR_0606 234 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110803016 Common rpsC 30S ribosomal protein S3 CPR_2393 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 110802946 Common - hypothetical protein CPR_2048 3 COG3247 HdeD, Uncharacterized conserved protein Function unknown 110802667 Common rplU 50S ribosomal protein L21 CPR_2097 199 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 110801829 Common - Cell envelope-related transcriptional attenuator domain family CPR_0271 61 COG1316 LytR, Transcriptional regulator Transcription 110803592 Common - sensor histidine kinase CPR_1023 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110803688 Common - D-alanyl-D-alanine carboxypeptidase family CPR_1943 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110801822 Common rpmD 50S ribosomal protein L30 CPR_2381 133 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 110802060 Common - Mrp protein CPR_2521 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110803785 Common - FliB family protein CPR_1272 6 None None None 110801982 Common - hypothetical protein CPR_1576 1 None None None 110802147 Common - dedA protein CPR_1475 155 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110802607 Common - hypothetical protein CPR_2321 1 None None None 110802370 Common - peptidase, M50 family CPR_1636 73 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110802165 Common cobI cobalt-precorrin-2 C(20)-methyltransferase CPR_1237 164 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 110802537 Pathogen - hypothetical protein CPR_0863 1 None None None 110803308 Common - O-methyltransferase family protein CPR_1742 117 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 110803781 Common - maltose ABC transporter, permease protein CPR_2336 157 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 110802386 Common - hypothetical protein CPR_2609 3 None None None 110802600 Common - hypothetical protein CPR_2578 3 None None None 110801491 Common - ISCpe4, transposase CPR_0811 66 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801997 Common - ferrichrome transport system, permease protein CPR_0796 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110803653 Common - thioredoxin reductase CPR_2349 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110803604 Common ribA riboflavin biosynthesis protein RibA CPR_0532 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 110802528 Common rpsF 30S ribosomal protein S6 CPR_2656 205 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 110802485 Common lysA diaminopimelate decarboxylase CPR_0562 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 110801978 Common - hypothetical protein CPR_1974 1 None None None 110803089 Common - HAD hydrolase, IIB family CPR_1541 144 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110802806 Common xerC site-specific tyrosine recombinase XerC CPR_1179 223 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110802284 Common - sensor histidine kinase CPR_0118 121 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802235 Common - hypothetical protein CPR_2030 5 None None None 110802124 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B CPR_1764 110 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 110801471 Common - hypothetical protein CPR_0665 9 None None None 110802269 Common - transport protein ysiA CPR_0433 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110801578 Common - anaerobic ribonucleoside-triphosphate reductase, putative CPR_1525 2 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 110802445 Common gltA putative oxidoreductase CPR_1263 190 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110802952 Common - hyaluronoglucosaminidase domain protein CPR_1842 7 None None None 110802145 Common rpoC DNA-directed RNA polymerase subunit beta' CPR_2407 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 110803703 Pathogen - hypothetical protein CPR_1467 1 None None None 110802001 Common rpmH 50S ribosomal protein L34 CPR_2674 12 None None None 110801737 Common apt adenine phosphoribosyltransferase CPR_1905 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110802275 Common - hypothetical protein CPR_2297 21 None None None 110803510 Common - helicase, RecD/TraA family CPR_2143 148 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 110802221 Common - hypothetical protein CPR_2652 18 COG4241 COG4241, Predicted membrane protein Function unknown 110802674 Pathogen - hypothetical protein CPR_1296 1 None None None 110801852 Common - teichuronic acid biosynthesis glycosyl transferase, putative CPR_0259 48 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110803092 Pathogen - prepilin peptidase-dependent CPR_2270 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110801678 Common - biotin synthase CPR_2462 194 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 110801532 Common - Domain of unknown function (DUF368) superfamily CPR_1370 47 COG2035 COG2035, Predicted membrane protein Function unknown 110802563 Common purR3 Transcriptional regulator CPR_2606 127 COG1609 PurR, Transcriptional regulators Transcription 110802609 Common dnaK chaperone protein DnaK CPR_2005 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 110802172 Common - ATP-binding transport protein nata CPR_0698 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 110801827 Common cotJC spore coat peptide assembly protein CotJC CPR_0934 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 110803437 Common sun sun protein CPR_1712 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 110801689 Common - sortase family protein CPR_0146 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110802907 Common - hypothetical protein CPR_1246 6 None None None 110803374 Common - probable transcription regulator, lacI/xre family CPR_2568 6 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 110801659 Common - uncharacterized conserved protein, YACZ CPR_2422 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 110802212 Common rpmB ribosomal protein L28 CPR_1705 54 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 110802482 Common pyrF orotidine 5'-phosphate decarboxylase CPR_1199 72 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 110802773 Common - beta-galactosidase i CPR_0156 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 110802526 Common aroB 3-dehydroquinate synthase CPR_0689 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 110802997 Common - chromate transport protein CPR_2215 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 110803365 Common pyrK dihydroorotate dehydrogenase electron transfer subunit CPR_1198 102 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110803860 Common ytaF putative sporulation protein YtaF CPR_2044 12 COG1971 COG1971, Predicted membrane protein Function unknown 110803644 Common - hypothetical protein CPR_0655 2 None None None 110801820 Common - hypothetical protein CPR_1978 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110802778 Common - hypothetical protein CPR_1015 5 None None None 110802647 Common - ferrichrome ABC transporter (binding protein)-like protein lin2288 CPR_0212 110 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110801779 Common - hypothetical protein CPR_0790 34 COG3681 COG3681, Uncharacterized conserved protein Function unknown 110802470 Common - transcriptional regulator, Crp/Fnr family CPR_0757 181 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110803917 Common - hypothetical protein CPR_1507 80 COG1742 COG1742, Uncharacterized conserved protein Function unknown 110801591 Common rpmC ribosomal protein L29 CPR_2391 145 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 110802500 Common - ROK family protein CPR_2047 129 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110801710 Common - lysM domain protein CPR_2189 16 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 110802713 Common - hypothetical protein CPR_1393 1 None None None 110803728 Common thiH thiamine biosynthesis protein ThiH CPR_0108 61 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 110802924 Common - oxacillin resistance-related FmtC protein CPR_1258 64 COG2898 COG2898, Uncharacterized conserved protein Function unknown 110802335 Pathogen - hypothetical protein CPR_0965 1 None None None 110803040 Common - pirin-like protein CPR_0776 68 COG1741 COG1741, Pirin-related protein General function prediction only 110803216 Common - pyridine nucleotide-disulphide oxidoreductase family protein CPR_0715 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 110801621 Common - glutamine-binding periplasmic protein of glutamine ABC transporter CPR_2062 195 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110803027 Common - ISCpe7, transposase CPR_0634 22 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803815 Common - IS1470, transposase CPR_1579 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801445 Common - undecaprenyl pyrophosphate phosphatase CPR_1204 195 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 110802515 Common - regulatory protein pfoR CPR_1056 44 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 110803848 Common - ribosomal protein S30AE family CPR_2140 172 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 110802964 Pathogen - hypothetical protein CPR_0836 1 None None None 110802311 Common - hypothetical protein CPR_1362 15 None None None 110803393 Common - transcription regulator CPR_0825 162 COG0640 ArsR, Predicted transcriptional regulators Transcription 110801769 Common prmA ribosomal protein L11 methyltransferase CPR_1999 192 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 110802621 Common - glutathione peroxidase CPR_1026 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 110802702 Common prfB peptide chain release factor 2 CPR_2138 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 110803162 Common - aldose 1-epimerase precursor CPR_1344 90 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 110803031 Common - sensor protein yycg CPR_2326 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802512 Common - sensor histidine kinase VncS CPR_2076 151 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802547 Pathogen - hypothetical protein CPR_1390 1 None None None 110801648 Common spoVAE stage V sporulation protein AE CPR_2017 15 None None None 110803908 Common - hypothetical protein CPR_0335 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 110802760 Common - hypothetical protein CPR_2323 6 COG1633 COG1633, Uncharacterized conserved protein Function unknown 110802219 Common - hypothetical protein CPR_2659 2 None None None 110801922 Common - ISCpe2, transposase orfA CPR_1566 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803923 Common - uncharacterized conserved protein, YHAD family CPR_0846 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 110802640 Pathogen - hypothetical protein CPR_1358 1 None None None 110803056 Common - hypothetical protein CPR_0323 3 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 110802598 Common - hypothetical protein CPR_1086 5 None None None 110802240 Common - hypothetical protein CPR_1514 3 None None None 110802552 Common - polysaccharide deacetylase CPR_1488 76 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110801650 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein CPR_1918 143 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110803277 Pathogen - hypothetical protein CPR_1435 1 None None None 110802226 Common - phosphomannomutase CPR_1841 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110802205 Common - hypothetical protein CPR_1404 14 COG4492 PheB, ACT domain-containing protein General function prediction only 110803168 Common - hypothetical protein CPR_0956 4 COG2456 COG2456, Uncharacterized conserved protein Function unknown 110801955 Common - ATP-dependent protease CPR_2023 170 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110803699 Common - DNA-binding response regulator CPR_0448 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110802022 Common - hypothetical protein CPR_1401 26 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 110801462 Pathogen - hypothetical protein CPR_1043 1 None None None 110803690 Common rpsG 30S ribosomal protein S7 CPR_2404 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 110801713 Common - acyl-ACP thioesterase family protein CPR_2637 19 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 110802689 Common - hypothetical protein CPR_1451 1 None None None 110802692 Common - tetratricopeptide repeat domain protein CPR_0639 23 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110802737 Common - hypothetical protein CPR_0294 7 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 110803962 Common - hypothetical protein CPR_0402 18 None None None 110803849 Common - hypothetical protein CPR_2345 24 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 110802055 Common - ferrichrome ABC transporter (permease)-like protein lin2287 CPR_0213 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110801669 Common secE preprotein translocase subunit SecE CPR_2414 5 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 110802395 Common - regulatory protein SpoVG CPR_2500 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 110803036 Common - hypothetical protein CPR_2524 1 None None None 110803836 Common cloSI clostripain CPR_0833 12 None None None 110802561 Common tuf elongation factor Tu CPR_2402 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 110802581 Common - acetyltransferase, GNAT family CPR_0853 2 COG0456 RimI, Acetyltransferases General function prediction only 110803556 Common - transcriptional regulator, AraC family CPR_1432 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110802309 Common - probable proton-coupled thiamine transporter YuaJ CPR_1364 12 COG3859 COG3859, Predicted membrane protein Function unknown 110803204 Common - PTS system enzyme II A component-like protein lmo1973 CPR_0489 58 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 110802247 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase CPR_1666 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 110803120 Common - VanZ like family family CPR_2575 7 None None None 110801527 Common - vncR, response regulator CPR_2077 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110803851 Common - probable acetyltransferase domain containing protein CPR_1153 47 COG0456 RimI, Acetyltransferases General function prediction only 110801614 Common - sugar ABC transporter CPR_1549 134 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 110802008 Common coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase CPR_1717 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 110801469 Pathogen - hypothetical protein CPR_0307 1 None None None 110802876 Pathogen - hypothetical protein CPR_0496 1 None None None 110801705 Common - Integral membrane protein domain protein CPR_0595 83 COG2510 COG2510, Predicted membrane protein Function unknown 110803997 Pathogen - hypothetical protein CPR_1806 1 None None None 110803113 Common mfd transcription-repair coupling factor CPR_2493 240 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 110803649 Common - hypothetical protein CPR_0895 4 None None None 110801728 Common - metallo-beta-lactamase family protein CPR_1902 224 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110801770 Common - ABC transporter, periplasmic substrate-binding protein, putative CPR_0904 118 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110802784 Common grpE co-chaperone GrpE CPR_2006 232 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 110801797 Common - ISCpe7, transposase CPR_0635 6 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802338 Common - hypothetical protein CPR_2328 2 None None None 110802453 Common - transcriptional regulator, Crp/Fnr family CPR_1062 177 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110802636 Common ruvB Holliday junction DNA helicase B CPR_1914 235 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 110803858 Common - hypothetical protein CPR_0061 1 None None None 110802087 Common - Hypothetical protein, CF-32 family CPR_0890 6 None None None 110803712 Common - DnaJ domain protein CPR_0207 174 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110803912 Common - hypothetical protein CPR_1122 34 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110803823 Common obgE GTPase ObgE CPR_2094 249 COG0536 Obg, Predicted GTPase General function prediction only 110801605 Common - cysteine synthase family protein CPR_0166 229 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 110801548 Common - hypothetical protein CPR_0290 61 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110803310 Common - hypothetical protein CPR_0936 1 None None None 110803137 Common - ABC transporter domain protein CPR_0297 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110801696 Common atpA F0F1 ATP synthase subunit alpha CPR_2164 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 110801850 Common udp uridine phosphorylase CPR_0370 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 110801934 Common - L-1,2-propanediol oxidoreductase CPR_0927 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110803071 Common nusB transcription antitermination protein NusB CPR_1792 198 COG0781 NusB, Transcription termination factor Transcription 110802477 Common - IS1470, transposase CPR_0379 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110803272 Common dapF diaminopimelate epimerase CPR_1814 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 110801680 Common purR purine operon repressor CPR_2501 47 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110803802 Pathogen bofA pro-sigmaK processing inhibitor BofA CPR_0059 1 None None None 110803072 Pathogen - hypothetical protein CPR_1357 1 None None None 110803723 Common - sensor histidine kinase CPR_0538 115 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 110803252 Pathogen - hypothetical protein CPR_0988 1 None None None 110802570 Common - hypothetical protein CPR_1304 12 None None None 110801523 Common - amidohydrolase family protein CPR_1106 172 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110803091 Common - ribonuclease, Rne/Rng family CPR_2098 187 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 110801962 Common - transcriptional repressor CPR_2440 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 110803504 Common - hypothetical protein CPR_2598 7 None None None 110803100 Common - permease CPR_1722 136 COG2252 COG2252, Permeases General function prediction only 110803458 Common - L-threonine-O-3-phosphate decarboxylase CPR_1114 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110803747 Common - hypothetical protein CPR_0269 8 None None None 110801968 Common - hypothetical protein CPR_1990 198 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 110803892 Common - tetratricopeptide repeat protein CPR_1288 106 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110803739 Common - alpha-mannosidase 2c1 CPR_0841 53 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 110802013 Common - hypothetical protein CPR_2543 1 None None None 110802657 Common - hypothetical protein CPR_2267 2 None None None 110801745 Pathogen - lipoprotein, putative CPR_0502 1 None None None 110801833 Common - MATE efflux family protein subfamily CPR_0814 136 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110803878 Common - capsule synthesis gene, putative CPR_0453 219 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110802850 Common - helicase domain protein CPR_2066 99 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110801871 Common - V-type ATP synthase subunit I CPR_1614 49 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 110803067 Common nadD nicotinic acid mononucleotide adenyltransferase CPR_2092 188 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 110802129 Common - hypothetical protein CPR_2025 1 None None None 110801843 Common - arylsulfatase regulator, putative CPR_0602 87 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 110803284 Common - potassium transporter family protein CPR_1046 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 110801562 Common - membrane lipoprotein tmpC precursor CPR_1306 105 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110802398 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative CPR_1407 204 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110803349 Common - Integral membrane protein domain protein CPR_0739 160 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 110802883 Pathogen - hypothetical protein CPR_0774 1 None None None 110802095 Pathogen - hypothetical protein CPR_1194 1 None None None 110803336 Common - hypothetical protein CPR_0785 5 None None None 110802976 Common - cation-transporting atpase pacl CPR_2026 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110801585 Common - oligopeptide ABC transporter, ATPase component CPR_2255 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110801671 Common - ISCpe2, transposase orfA CPR_0710 7 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803118 Common - transcriptional regulator, AbrB family CPR_0268 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110803000 Common pyk pyruvate kinase CPR_2116 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110802383 Pathogen - hypothetical protein CPR_1159 1 None None None 110803280 Common - Single-strand binding protein family CPR_1639 37 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110803366 Common pfl formate acetyltransferase CPR_1169 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 110803946 Common - transmembrane permease MsmF CPR_0905 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110803692 Common galU UTP-glucose-1-phosphate uridylyltransferase CPR_0469 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110802596 Common - S4 domain protein CPR_1820 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 110803559 Common - hypothetical protein CPR_0352 1 None None None 110801892 Common hemC porphobilinogen deaminase CPR_1422 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 110803188 Common pnpA polynucleotide phosphorylase/polyadenylase CPR_1652 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 110803471 Pathogen - hypothetical protein CPR_1379 1 None None None 110801882 Common secF preprotein translocase subunit SecF CPR_1907 220 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 110803980 Common - khg/kdpg aldolase CPR_0393 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 110803948 Common - tetratricopeptide repeat domain protein CPR_1946 13 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110803788 Common prsA ribose-phosphate pyrophosphokinase CPR_2498 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110802381 Common - hypothetical protein CPR_2251 83 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 110802069 Common - hypothetical protein CPR_0365 5 COG1633 COG1633, Uncharacterized conserved protein Function unknown 110803536 Common cbiD cobalt-precorrin-6A synthase CPR_1240 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 110801906 Common - Acyltransferase family, putative CPR_0199 24 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 110802841 Common - hypothetical protein CPR_0824 3 None None None 110802464 Common - methyltransferase, UbiE/COQ5 family CPR_0164 191 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110802857 Common - hypothetical protein CPR_1964 1 None None None 110803433 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type CPR_1539 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110802406 Common - 6-phosphofructokinase CPR_1446 158 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110801597 Pathogen - hypothetical protein CPR_1632 1 None None None 110802734 Common - ribose-5-phosphate isomerase B CPR_2173 129 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 110803508 Common - hypothetical protein CPR_0431 1 None None None 110802336 Pathogen - hypothetical protein CPR_0703 1 None None None 110803989 Common - hypothetical protein CPR_1683 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 110802053 Pathogen - hypothetical protein CPR_0964 2 None None None 110803388 Common - HDIG/HD domain protein CPR_1097 6 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110801781 Common - F5/8 type C domain protein CPR_0640 16 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 110803501 Common - hypothetical protein CPR_1214 32 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 110802347 Common - peptidase, M16 family CPR_1890 199 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110802965 Common - hypothetical protein CPR_0308 9 None None None 110803663 Pathogen - ISCpe5, transposase CPR_0760 1 None None None 110803442 Common - Glutaredoxin CPR_2433 68 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110803775 Common - hypothetical protein CPR_2114 128 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110803229 Common mraW S-adenosyl-methyltransferase MraW CPR_1833 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 110802182 Common - hypothetical protein CPR_0995 1 None None None 110803930 Pathogen - hypothetical protein CPR_0791 1 None None None 110802781 Common spoVB stage V sporulation protein B CPR_2490 64 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110802939 Common - probable permease, putative CPR_0707 199 COG0628 PerM, Predicted permease General function prediction only 110802049 Common rumA 23S rRNA (uracil-5-)-methyltransferase RumA CPR_2082 195 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 110802254 Common atpE ATP synthase F0, C subunit CPR_2167 2 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 110803491 Pathogen - hypothetical protein CPR_1254 1 None None None 110801458 Common gatY tagatose-bisphosphate aldolase CPR_2645 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 110803245 Common - hypothetical protein CPR_0548 70 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 110801473 Common - translation elongation factor G, putative CPR_1042 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110802433 Common - GntR family transcription regulator CPR_2291 11 COG2188 PhnF, Transcriptional regulators Transcription 110801991 Common - ISCpe7, transposase CPR_1190 17 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803576 Common - putative acyl carrier protein phosphodiesterase 1 CPR_0519 62 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 110802020 Pathogen - hypothetical protein CPR_0666 1 None None None 110802267 Common - hypothetical protein CPR_0945 2 None None None 110802613 Common murG N-acetylglucosaminyl transferase CPR_2034 209 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110802491 Common - rubrerythrin CPR_0099 22 COG1592 COG1592, Rubrerythrin Energy production and conversion 110801863 Common - IS1470, transposase CPR_0314 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110802788 Common - DNA-binding response regulator, AraC family CPR_2056 226 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110802971 Common - ABC transporter, permease/ATP-binding protein CPR_0363 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110802156 Common ftsY signal recognition particle-docking protein FtsY CPR_1687 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 110803326 Common - hypothetical protein CPR_1433 3 None None None 110802838 Common atpF ATP synthase F0, B subunit CPR_2166 132 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 110801877 Common - DNA-binding response regulator CPR_0609 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110803222 Common - Bdr family protein CPR_2347 1 None None None 110802835 Common ftsK DNA translocase FtsK CPR_1648 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 110803886 Common secD preprotein translocase subunit SecD CPR_1908 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 110802494 Common cysK cysteine synthase A CPR_1322 223 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 110802893 Common trpS tryptophanyl-tRNA synthetase CPR_0600 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803217 Common - LD-carboxypeptidase family protein CPR_2464 78 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110803377 Common - hypothetical protein CPR_2310 1 COG1403 McrA, Restriction endonuclease Defense mechanisms 110803045 Common - ribosomal protein L7AE family CPR_2406 14 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 110802170 Common - chorismate mutase CPR_0692 12 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 110803482 Common - rubredoxin CPR_0755 118 COG1773 COG1773, Rubredoxin Energy production and conversion 110802890 Common - IS1470, transposase CPR_0648 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801756 Common - acetyltransferase, GNAT family CPR_0856 7 None None None 110803381 Common nadA quinolinate synthetase CPR_0376 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 110801567 Common - hypothetical protein CPR_1024 2 None None None 110803581 Common - 4Fe-4S binding domain protein/radical SAM domain protein CPR_0637 83 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110801589 Common purA adenylosuccinate synthetase CPR_2641 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 110801973 Common - GGDEF domain protein CPR_1035 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110803325 Common - dipeptidase family protein CPR_1894 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 110802302 Common - carbohydrate kinase family protein CPR_0283 220 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 110803528 Common rpoD RNA polymerase sigma factor RpoD CPR_1975 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 110802203 Common - hypothetical protein CPR_1330 1 None None None 110801558 Common - DHH family protein CPR_2651 89 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 110802699 Common - hypothetical protein CPR_1615 13 None None None 110802163 Common accC biotin carboxylase CPR_1142 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 110803011 Common - hypothetical protein CPR_0752 24 COG2461 COG2461, Uncharacterized conserved protein Function unknown 110803521 Common recQ ATP-dependent DNA helicase RecQ CPR_0328 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 110802863 Common - hypothetical protein CPR_0243 5 None None None 110802602 Common jag SpoIIIJ-associated protein CPR_2670 71 COG1847 Jag, Predicted RNA-binding protein General function prediction only 110803779 Common cwlD N-acetylmuramoyl-L-alanine amidase CPR_2361 174 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110801653 Common - sodium:dicarboxylate symporter family protein CPR_1183 109 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110803846 Common adh1 NADPH-dependent butanol dehydrogenase CPR_1265 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110802672 Common - antibiotic ABC transporter, ATP-binding protein CPR_0817 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110802903 Pathogen - hypothetical protein CPR_2446 1 None None None 110801538 Common - methenyltetrahydrofolate cyclohydrolase CPR_1837 33 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 110801611 Common tig trigger factor CPR_1386 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 110802680 Common citE citrate lyase, beta subunit CPR_1164 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 110803783 Common - adp-ribose pyrophosphatase CPR_1779 127 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110803403 Pathogen - hypothetical protein CPR_0977 1 None None None 110802384 Common - polysaccharide deacetylase family protein CPR_1456 110 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110802604 Common purE phosphoribosylaminoimidazole carboxylase, catalytic subunit CPR_0670 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 110802286 Common - heme/steroid binding domain protein CPR_2508 2 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 110802361 Common - sodium:solute transporter CPR_0176 166 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 110802954 Pathogen - hypothetical protein CPR_0654 1 None None None 110801541 Common nagA N-acetylglucosamine-6-phosphate deacetylase CPR_2144 123 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 110802776 Common - Cytochrome C biogenesis protein transmembrane region family CPR_0721 195 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 110803352 Common - TrpR-like protein YerC/YecD CPR_2329 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 110802277 Common - rubredoxin/rubrerythrin CPR_0682 22 COG1592 COG1592, Rubrerythrin Energy production and conversion 110803138 Common - creatininase, putative CPR_0738 36 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110802487 Common - hypothetical protein CPR_0807 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 110802126 Common - MATE efflux family protein CPR_0848 181 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110801825 Common typA GTP-binding protein TypA CPR_1744 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 110803612 Common - hypothetical protein CPR_2241 2 None None None 110803676 Common - hypothetical protein CPR_2657 27 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 110802143 Common fhs formate--tetrahydrofolate ligase CPR_2471 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 110802616 Common - hypothetical protein CPR_2535 9 COG4129 COG4129, Predicted membrane protein Function unknown 110803619 Common - hypothetical protein CPR_0751 44 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 110802828 Pathogen - hypothetical protein CPR_0860 1 None None None 110803248 Common - laminarinase CPR_2607 53 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 110803869 Pathogen - hypothetical protein CPR_1595 1 None None None 110801854 Common - spore maturation protein B CPR_2541 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 110802237 Common - radical SAM protein, TIGR01212 family CPR_2563 90 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 110803709 Pathogen - hypothetical protein CPR_0481 2 None None None 110802726 Common - hypothetical protein CPR_1747 19 None None None 110803632 Pathogen - hypothetical protein CPR_0960 1 None None None 110803126 Pathogen - hypothetical protein CPR_1037 1 None None None 110801762 Pathogen - hypothetical protein CPR_0124 1 None None None 110801899 Common - hypothetical protein CPR_0644 2 None None None 110801498 Common - oxidoreductase, short-chain dehydrogenase/reductase family CPR_2585 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110801516 Common - GGDEF/EAL domain protein CPR_0235 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110803341 Common - nitroreductase family protein fused to ferredoxin domain CPR_0979 50 COG0778 NfnB, Nitroreductase Energy production and conversion 110801927 Common - von Willebrand factor type A domain protein CPR_0484 1 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 110801682 Common - PSP1 domain protein CPR_2443 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 110803883 Common - spermidine/putrescine ABC transporter, permease protein (potB)-like protein CPR_1936 213 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110802297 Common recX recombination regulator RecX CPR_1889 69 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 110801551 Common gcp O-sialoglycoprotein endopeptidase CPR_2202 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 110802586 Common - DNA helicase II related protein, putative CPR_0349 7 None None None 110803519 Common - hypothetical protein CPR_1590 4 None None None 110803639 Common - hyaluronoglucosaminidase precursor CPR_1249 9 None None None 110802130 Common - hypothetical protein CPR_2175 1 None None None 110802320 Common - sucrose-6-phosphate hydrolase CPR_1511 51 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 110802815 Common prfA peptide chain release factor 1 CPR_2176 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 110801582 Common - stage III sporulation protein AA CPR_1801 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 110803898 Common - hypothetical protein CPR_1118 53 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 110803148 Common - ISCpe7, transposase CPR_0809 49 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802074 Common - hypothetical protein CPR_0734 2 None None None 110801571 Common - lipase, putative CPR_0299 63 COG0657 Aes, Esterase/lipase Lipid metabolism 110801805 Common - response regulator CPR_0829 3 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110803214 Common - putative lipoprotein CPR_1508 7 COG5298 COG5298, Uncharacterized protein conserved in bacteria Function unknown 110802509 Common hlyIII hemolysin III CPR_1882 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 110802751 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CPR_1497 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110803469 Common - putative surface protein CPR_0145 11 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110802414 Common tilS tRNA(Ile)-lysidine synthetase CPR_2474 213 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110802304 Common - Na+ driven multidrug efflux pump CPR_1218 156 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110803570 Common - probable chromate transport protein, putative CPR_2214 55 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 110802401 Common - hypothetical protein CPR_1478 18 COG4708 COG4708, Predicted membrane protein Function unknown 110803977 Common argR arginine repressor CPR_0161 35 COG1438 ArgR, Arginine repressor Transcription 110803018 Common - iron(III) dicitrate transport permease-like protein yusV CPR_0781 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110803856 Common truB tRNA pseudouridine synthase B CPR_1655 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 110802765 Common - hypothetical protein CPR_1898 96 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 110802032 Common - beta-galactosidase CPR_0750 69 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 110803456 Pathogen - hypothetical protein CPR_0882 1 None None None 110803793 Common - glucuronyl hydrolase CPR_0396 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 110801966 Common rplA 50S ribosomal protein L1 CPR_2411 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 110802245 Pathogen - hypothetical protein CPR_0578 1 None None None 110803407 Common - hypothetical protein CPR_0149 25 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110801646 Common - radical SAM domain protein CPR_2100 66 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 110802239 Common - Amino acid permease CPR_0155 110 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110803165 Pathogen - hypothetical protein CPR_0876 1 None None None 110802015 Common - 7-alpha-hydroxysteroid dehydrogenase CPR_0991 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110803354 Common proB gamma-glutamyl kinase CPR_2583 195 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 110802549 Common - hypothetical protein CPR_1259 12 COG0392 COG0392, Predicted integral membrane protein Function unknown 110802333 Common - hypothetical protein CPR_2325 34 None None None 110802550 Common thiF thiamine biosynthesis protein ThiF CPR_1572 196 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 110802137 Common - putative aminopeptidase 1 CPR_1076 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 110803906 Common - hypothetical protein CPR_0535 7 None None None 110803614 Common - nudix (MutT) family hydrolase CPR_1862 120 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110802228 Common - 67 kDa myosin-cross-reactive antigen family protein CPR_0362 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 110802739 Common - pseudouridylate synthase family protein, yabo CPR_2089 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110803422 Common - hypothetical protein CPR_1629 1 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 110803449 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase CPR_0675 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 110801661 Common trxB thioredoxin-disulfide reductase CPR_2436 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110802024 Common - glycosyl transferase, group 2 family protein CPR_2042 120 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110803429 Common - secretion system protein E CPR_2272 220 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 110803630 Common - fructokinase CPR_0909 167 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110802698 Common - ferritin family protein CPR_1047 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 110803833 Common sfsA sugar fermentation stimulation protein A CPR_0560 108 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 110802328 Common - transcriptional regulator, GntR family CPR_2000 78 COG1725 COG1725, Predicted transcriptional regulators Transcription 110803950 Pathogen - hypothetical protein CPR_0483 1 None None None 110803543 Common - CAAX amino terminal protease family protein CPR_0234 11 None None None 110802489 Pathogen - hypothetical protein CPR_0200 1 None None None 110803347 Common - hypothetical protein CPR_0085 1 None None None 110803700 Common codA cytosine deaminase CPR_0737 75 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110802740 Common - D-alanyl-D-alanine carboxypeptidase family CPR_2088 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110802638 Common - DNA-binding response regulator, LytTr family CPR_1482 124 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 110803159 Common - sensor histidine kinase/response regulator CPR_1493 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110803338 Common - hypothetical protein CPR_2618 6 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 110801988 Common - alpha-ribazole-5-phosphate phosphatase, putative CPR_1112 6 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110802379 Common rubY rubrerythrin CPR_0132 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 110802521 Common - hypothetical protein CPR_1286 4 None None None 110802540 Common - hypothetical protein CPR_1727 30 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 110803294 Pathogen - hypothetical protein CPR_0355 3 None None None 110803440 Common mutS DNA mismatch repair protein CPR_1171 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110803058 Common rpoZ DNA-directed RNA polymerase subunit omega CPR_1718 33 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 110802745 Common - 6-phospho-beta-glucosidase bgla CPR_2603 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 110801759 Common - hypothetical protein CPR_1966 2 None None None 110802517 Common - alpha/beta hydrolase domain protein CPR_0169 139 COG0657 Aes, Esterase/lipase Lipid metabolism 110803038 Common - hypothetical protein CPR_0524 2 None None None 110802115 Common - hypothetical protein CPR_0043 22 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110801623 Common - Predicted metal-dependent phosphoesterase (PHP family) CPR_1092 126 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110802484 Common - membrane lipoprotein tmpc precursor CPR_1552 86 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110801631 Common - polyferredoxin, putative CPR_2063 15 COG0716 FldA, Flavodoxins Energy production and conversion 110802995 Common - hypothetical protein CPR_1348 70 COG2323 COG2323, Predicted membrane protein Function unknown 110803439 Common - sortase family protein CPR_0211 33 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110803263 Pathogen - hypothetical protein CPR_1982 1 None None None 110803401 Common - proton/sodium-glutamate symport protein CPR_0742 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110802210 Common eno phosphopyruvate hydratase CPR_1295 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 110802771 Common - sugar ABC transporter ATP binding protein alr5362 CPR_1551 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 110803098 Common ackA acetate kinase CPR_1695 162 COG0282 ackA, Acetate kinase Energy production and conversion 110802646 Common - peptidase, putative CPR_0480 21 None None None 110802679 Common lgt prolipoprotein diacylglyceryl transferase CPR_0046 142 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 110801652 Common - hypothetical protein CPR_1503 1 None None None 110803418 Common - hypothetical protein CPR_0411 12 COG4905 COG4905, Predicted membrane protein Function unknown 110802700 Common - glycosyltransferase ycbB CPR_0957 43 None None None 110803299 Common - phosphoglycerate mutase family protein CPR_0100 149 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110803910 Common ung uracil-DNA glycosylase CPR_0249 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 110803143 Common - acetyltransferase, GNAT family CPR_0858 85 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110802270 Common - GTP pyrophosphokinase CPR_1904 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 110803862 Common - transcriptional regulator, MerR family CPR_0445 99 COG0789 SoxR, Predicted transcriptional regulators Transcription 110803395 Common - Cell envelope-related transcriptional attenuator domain family CPR_0598 55 COG1316 LytR, Transcriptional regulator Transcription 110802120 Common - DNA polymerase III subunit epsilon CPR_1394 113 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 110803726 Common - IS1470, transposase CPR_0659 57 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110802568 Common - hypothetical protein CPR_0517 8 COG3326 COG3326, Predicted membrane protein Function unknown 110801915 Common - hypothetical protein CPR_0423 20 COG3538 COG3538, Uncharacterized conserved protein Function unknown 110803234 Common rbsB ABC-type sugar transport system, periplasmic component CPR_1599 128 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110803105 Common atpG F0F1 ATP synthase subunit gamma CPR_2163 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 110803177 Pathogen - hypothetical protein CPR_0482 1 None None None 110803042 Common - hemolysin A CPR_1786 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 110803002 Common gltX glutamyl-tRNA synthetase CPR_1067 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110801957 Common rpoB DNA-directed RNA polymerase subunit beta CPR_2408 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 110803317 Common - comC competence related protein, putative CPR_2016 113 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 110801743 Common hfq RNA chaperone Hfq CPR_1174 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 110802655 Common - cell division protein FtsL, putative CPR_1832 1 None None None 110803758 Common - ABC transporter domain protein CPR_2003 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110801767 Pathogen - hypothetical protein CPR_0826 1 None None None 110802475 Common - heavy metal binding protein CPR_2118 22 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 110802217 Common - probable kinase yeiC, putative CPR_1461 126 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110801740 Common - ATP-dependent DNA helicase RecG CPR_1702 227 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 110803361 Common - sensor histidine kinase HpkA CPR_2209 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802348 Common - DHH subfamily 1 protein CPR_1656 84 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 110802530 Pathogen - hypothetical protein CPR_0122 1 None None None 110802628 Common - 16S pseudouridylate synthase CPR_2249 200 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110803005 Common - ABC transporter, ATP-binding/permease protein CPR_0216 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110803068 Common fixB 3-hydroxybutyryl-CoA dehydrogenase CPR_2284 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 110802859 Common - 3D/G5 domain protein CPR_2528 33 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 110802852 Common - oligoendopeptidase, M3 family CPR_2318 74 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 110801845 Common - competence damage-inducible protein A CPR_0128 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 110801831 Common - mechanosensitive ion channel family protein CPR_2658 194 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110803814 Common - Orn/Lys/Arg decarboxylase CPR_0514 92 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 110803749 Common - transcriptional regulator, AsnC family CPR_1625 128 COG1522 Lrp, Transcriptional regulators Transcription 110802874 Common greA transcription elongation factor GreA CPR_2468 204 COG0782 GreA, Transcription elongation factor Transcription 110802881 Common - transcriptional regulator, Crp/Fnr family CPR_0754 174 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110801897 Common - hypothetical protein CPR_1068 14 None None None 110803313 Common spoIIID stage III sporulation protein D CPR_2156 15 None None None 110803807 Common - glycine betaine/carnitine/choline ABC transporter, permease/substrate-binding protein CPR_0522 179 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 110803809 Common rnr ribonuclease R CPR_1292 200 COG0557 VacB, Exoribonuclease R Transcription 110801587 Common - glutathione peroxidase CPR_0867 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 110803821 Common sigF sporulation sigma factor SigF CPR_2020 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110803116 Common - Bacterial membrane flanked domain family CPR_1490 11 COG3428 COG3428, Predicted membrane protein Function unknown 110803894 Common rpsI 30S ribosomal protein S9 CPR_2363 246 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 110802093 Common - ferripyochelin binding protein CPR_1622 209 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 110802208 Common - ABC transporter, substrate-binding protein CPR_0476 106 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110802984 Common - bacterial hemoglobin CPR_1921 77 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 110801525 Pathogen - hypothetical protein CPR_2311 1 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110801812 Common - hypothetical protein CPR_0039 10 None None None 110801725 Common - lipoprotein, putative CPR_1100 1 None None None 110803220 Common - Pyruvate kinase, barrel domain CPR_1103 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110803074 Common - stage III sporulation protein AD CPR_1798 15 None None None 110802803 Common - stage V sporulation protein D CPR_0528 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110803190 Common - signal peptidase I CPR_1523 152 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110801715 Common - V-type ATP synthase subunit F CPR_1610 9 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 110802574 Common idhA D-lactate dehydrogenase CPR_0499 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110801560 Common - metallo-beta-lactamase family protein CPR_0770 85 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110803965 Common smc chromosome segregation protein SMC CPR_1688 210 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110801569 Common - pyridine nucleotide-disulphide oxidoreductase family protein CPR_1025 148 COG2081 COG2081, Predicted flavoproteins General function prediction only 110802786 Common - teichoic acid ABC transporter, ATP-binding protein CPR_0258 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110801885 Common - IS1470, transposase CPR_1088 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801726 Common - Putative neutral zinc metallopeptidase superfamily CPR_1713 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 110803431 Common - cell division ATP-binding protein FtsE, putative CPR_0291 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 110801504 Common - sensor histidine kinase CPR_2496 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110803195 Common - transcription accessory protein CPR_2136 221 COG2183 Tex, Transcriptional accessory protein Transcription 110802665 Common - hypothetical protein CPR_1677 45 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 110802943 Common - glycosyltransferase, putative CPR_0454 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110802141 Common - ABC transporter, ATP-binding protein CPR_1021 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110803111 Common recJ single-stranded-DNA-specific exonuclease RecJ CPR_2036 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110803368 Common hydA iron hydrogenase CPR_2341 183 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110801961 Common - ISCpe2, transposase orfA CPR_0471 71 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803995 Common - hypothetical protein CPR_2376 3 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 110803637 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CPR_2159 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 110802539 Common - signal peptidase I CPR_0564 172 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110803135 Pathogen - hypothetical protein CPR_0601 1 None None None 110801932 Common - CoA-substrate-specific enzyme activase, putative CPR_1215 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 110802843 Common nrdR hypothetical protein CPR_1730 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 110803629 Common rpsK 30S ribosomal protein S11 CPR_2372 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 110802989 Common dnaG DNA primase CPR_1976 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 110801941 Common - hydrolase, TatD family CPR_2529 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 110802455 Common - hydroxyacid oxidase 2 CPR_1844 155 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 110802572 Pathogen - hypothetical protein CPR_0884 1 None None None 110803544 Common scrR sucrose operon repressor CPR_1512 128 COG1609 PurR, Transcriptional regulators Transcription 110801694 Common - HAD hydrolase, IIB family CPR_0579 149 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110803753 Common tgt queuine tRNA-ribosyltransferase CPR_1912 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 110803270 Common speB agmatinase CPR_0516 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 110801707 Common xseB exodeoxyribonuclease VII small subunit CPR_1789 20 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 110803250 Common - lactococcin g processing and transport ATP-binding protein CPR_0658 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 110803606 Common - DHH domain protein CPR_1906 155 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110803959 Common cbiE precorrin-6y C5,15-methyltransferase (decarboxylating) CPR_1239 71 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 110801443 Common - hypothetical protein CPR_0913 54 COG2378 COG2378, Predicted transcriptional regulator Transcription 110803257 Common cbiT precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit CPR_1238 68 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 110801521 Common - ABC transporter domain protein CPR_1487 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110802119 Common - hypothetical protein CPR_1041 55 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 110801890 Common - phosphate butyryltransferase CPR_2343 129 COG0280 Pta, Phosphotransacetylase Energy production and conversion 110802199 Common - acetyltransferase, GNAT family CPR_0798 31 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110803032 Common - vancomycin b-type resistance protein vanW, putative CPR_1209 34 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 110801993 Common rpsP 30S ribosomal protein S16 CPR_1684 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 110803979 Common - adherence and virulence protein A CPR_1815 92 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 110803012 Common pth peptidyl-tRNA hydrolase CPR_2494 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 110802584 Common ptsG PTS system, glucose-specific IIBC component CPR_2124 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110802374 Common - maltose-binding periplasmic protein precursor CPR_2338 87 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 110802802 Common - ISCpe2, transposase orfB CPR_0407 46 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802663 Common - putative methyltransferase CPR_0075 100 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110802121 Common - hypothetical protein CPR_1148 28 None None None 110803453 Common - hypothetical protein CPR_0357 42 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110801574 Pathogen - hypothetical protein CPR_0849 1 None None None 110802922 Pathogen - hypothetical protein CPR_0887 1 None None None 110802179 Common - hypothetical protein CPR_0309 8 COG5523 COG5523, Predicted integral membrane protein Function unknown 110801734 Common - NADP-dependent glyceraldehyde-3-phosphate dehydrogenase CPR_2434 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110803682 Common - hypothetical protein CPR_0346 2 None None None 110802498 Pathogen - hypothetical protein CPR_0946 1 None None None 110803899 Common - transcriptional regulator, PadR family CPR_2519 24 COG1695 COG1695, Predicted transcriptional regulators Transcription 110803966 Common glr2000 transporter CPR_1979 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110803104 Common nusG transcription antitermination protein NusG CPR_2413 215 COG0250 NusG, Transcription antiterminator Transcription 110801733 Common - transcriptional regulator, PadR family CPR_0649 61 COG1695 COG1695, Predicted transcriptional regulators Transcription 110801786 Common - PTS system, IIB component CPR_0397 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 110802611 Common - hypothetical protein CPR_0881 3 None None None 110803572 Common - hypothetical protein CPR_0921 3 None None None 110803638 Common - glycogen synthase CPR_0082 133 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 110803330 Common - sulfite reductase, iron-sulfur subunit CPR_1427 31 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 110802317 Common - PRC-barrel domain protein CPR_1651 7 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110803595 Common - hypothetical protein CPR_0726 5 None None None 110801672 Common - galactose-1-phosphate uridylyltransferase CPR_1346 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 110803563 Common - NAD-dependent 4-hydroxybutyrate dehydrogenase CPR_0507 169 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110801466 Common - LysM domain protein CPR_0862 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110803655 Common - alanine racemase, putative CPR_1133 159 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 110801688 Common ribE riboflavin synthase subunit alpha CPR_0531 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 110803463 Common rbgA ribosomal biogenesis GTPase CPR_1679 100 COG1161 COG1161, Predicted GTPases General function prediction only 110803086 Common - hypothetical protein CPR_1216 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 110802411 Pathogen - hypothetical protein CPR_0050 1 None None None 110803971 Common - anaerobic Cobalt chelatase, cbiK CPR_1242 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 110801497 Common - toxin secretion/phage lysis holin CPR_0366 12 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 110801976 Common - hypothetical protein CPR_1560 3 None None None 110802300 Common - Glutaredoxin-like protein, YruB-family CPR_2435 25 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110802865 Common - hypothetical protein CPR_2183 14 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 110802741 Common - glycerol uptake facilitator glpF CPR_2561 131 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 110802231 Common - hypothetical protein CPR_1374 1 None None None 110801857 Common - CRISPR-associated protein Cas2 CPR_0917 37 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 110802956 Common - sensor histidine kinase CPR_1002 110 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 110803146 Common - MutS domain V protein CPR_0886 197 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110802753 Pathogen - hypothetical protein CPR_2248 1 None None None 110801459 Common cobD cobalamin biosynthesis protein CobD CPR_1113 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 110802825 Common - acetyltransferase, GNAT family CPR_1014 19 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110803339 Common - phosphate ABC transporter (binding protein)-like protein lin2642 CPR_0604 184 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 110803867 Common - hypothetical protein CPR_0632 5 None None None 110803613 Common - SPFH domain protein/band 7 family protein CPR_1132 221 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110803786 Common lexA LexA repressor CPR_1177 175 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 110803791 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CPR_1664 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 110801751 Pathogen - hypothetical protein CPR_2262 1 None None None 110802312 Common - aluminum resistance protein CPR_1175 30 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 110801998 Common rpsE 30S ribosomal protein S5 CPR_2382 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 110803799 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CPR_1830 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110803525 Common - TPR domain protein CPR_1840 22 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110802271 Common glgB glycogen branching enzyme CPR_0081 151 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 110803766 Common - glycoprotease family protein CPR_2133 183 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 110803714 Common - metallo-beta-lactamase superfamily domain protein CPR_0732 2 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 110803153 Common - PTS system, IIB component CPR_2602 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 110801783 Common - DHHA1 domain protein CPR_0705 111 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801758 Common - 8-oxoguanine DNA glycosylase, putative CPR_2279 24 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 110802678 Common bcd butyryl-CoA dehydrogenase CPR_2286 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110801723 Common - hypothetical protein CPR_1437 17 COG3339 COG3339, Uncharacterized conserved protein Function unknown 110802005 Common - peptidase, U32 family CPR_1741 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 110803350 Common deaD ATP-dependent RNA helicase DeaD CPR_0847 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110803762 Common - hypothetical protein CPR_0137 57 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 110802582 Common - peptidase, putative CPR_2157 161 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110803901 Common - two CBS domain containing protein CPR_2120 10 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 110803532 Common - DNA polymerase III subunit delta' CPR_2444 191 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 110802132 Common - hypothetical protein CPR_1526 42 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110803383 Common gidB glucose-inhibited division protein B CPR_2667 201 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 110803484 Common - stage III sporulation protein AG CPR_1795 15 None None None 110802113 Common - primase-like protein CPR_2527 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 110802709 Common cstA carbon starvation protein CstA CPR_0725 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 110801514 Common - glutamate decarboxylase CPR_2029 66 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 110802439 Common trmB tRNA (guanine-N(7))-methyltransferase CPR_0422 139 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 110803328 Common pcrA ATP-dependent DNA helicase PcrA CPR_2246 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110802431 Common uvrC excinuclease ABC subunit C CPR_0333 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 110802837 Common rplC 50S ribosomal protein L3 CPR_2399 246 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 110802192 Common - CAAX amino terminal protease family protein CPR_1085 26 None None None 110802168 Common - IS1470, transposase CPR_0967 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110802938 Common rpsM 30S ribosomal protein S13 CPR_2373 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 110803669 Common - sensor histidine kinase CPR_2358 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802288 Common folBK dihydroneopterin aldolase/ 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CPR_1099 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 110802255 Common - glutamine synthetase, putative CPR_2573 222 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 110802606 Pathogen - hypothetical protein CPR_0107 1 None None None 110802427 Common - phosphoribulokinase / uridine kinase family protein CPR_1347 66 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 110801840 Common - sugar kinase, ribokinase family CPR_0394 98 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110803580 Common secG preprotein translocase subunit SecG CPR_1293 9 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 110803888 Common - oligopeptide ABC transporter, permease component CPR_2256 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110801875 Common hslO Hsp33-like chaperonin CPR_1868 134 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 110801714 Common - choloylglycine hydrolase family protein CPR_1155 39 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 110803212 Common - multidrug resistance protein 1 CPR_0215 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 110802353 Common - hypothetical protein CPR_1468 1 None None None 110802420 Common - hypothetical protein CPR_0217 7 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 110801818 Common - Voltage gated chloride channel family CPR_1884 165 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110802977 Common - stage V sporulation protein R CPR_1332 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 110801803 Common - metallo-beta-lactamase family/flavodoxin CPR_0275 93 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110801501 Common - hypothetical protein CPR_0874 3 None None None 110803369 Common - catabolite control protein A, putative CPR_2548 129 COG1609 PurR, Transcriptional regulators Transcription 110803128 Common - hypothetical protein CPR_0832 19 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110802911 Pathogen - hypothetical protein CPR_0697 1 None None None 110802034 Common - transcription regulator LytR-like protein lin0463 CPR_2090 64 COG1316 LytR, Transcriptional regulator Transcription 110801849 Common rpsD 30S ribosomal protein S4 CPR_2371 220 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 110802292 Common - acyl-CoA thioesterase, putative CPR_2204 29 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110801552 Common - ISCpe2, transposase orfB CPR_0506 69 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802905 Common - maltose ABC transporter, permease protein CPR_2337 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110801545 Common - hypothetical protein CPR_0010 5 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 110802685 Common mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase CPR_0066 101 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 110801981 Common - peptidase family protein CPR_2137 24 COG2234 Iap, Predicted aminopeptidases General function prediction only 110802377 Pathogen - hypothetical protein CPR_1941 1 None None None 110803940 Common - oligo-1,6-glucosidase CPR_0417 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110802892 Common - hypothetical protein CPR_1470 8 None None None 110802085 Common - hypothetical protein CPR_0883 41 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110801943 Common - transketolase CPR_0288 231 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 110802266 Common guaB inositol-5-monophosphate dehydrogenase CPR_2261 244 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 110801801 Pathogen - hypothetical protein CPR_0060 1 None None None 110803243 Pathogen - hypothetical protein CPR_2247 1 None None None 110802139 Pathogen - hypothetical protein CPR_0104 1 None None None 110803579 Common - hypothetical protein CPR_0218 21 None None None 110802895 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CPR_2186 199 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 110802281 Common - Endodeoxyribonuclease RusA family CPR_2203 2 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 110802118 Common - hypothetical protein CPR_1369 1 None None None 110803255 Common - BRO family, N-terminal domain protein CPR_0139 11 COG3617 COG3617, Prophage antirepressor Transcription 110803932 Common - Na+/H+ antiporter family family CPR_2536 79 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 110803225 Common - branched-chain amino acid aminotransferase, putative CPR_1095 156 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110802695 Common - hypothetical protein CPR_2300 1 None None None 110802349 Common - hydrolase, NUDIX family CPR_0561 86 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 110802797 Common rplM 50S ribosomal protein L13 CPR_2364 221 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 110802067 Common - hypothetical protein CPR_1178 1 None None None 110802849 Common - transglutaminase domain protein CPR_1888 32 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 110801868 Common - integral membrane protein CPR_2277 7 COG4478 COG4478, Predicted membrane protein Function unknown 110802794 Common - hypothetical protein CPR_1211 1 None None None 110801956 Common - Ser/Thr protein phosphatase family CPR_0374 58 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 110802555 Common ribH riboflavin synthase subunit beta CPR_0533 228 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 110802851 Common - hypothetical protein CPR_1412 16 COG2105 COG2105, Uncharacterized conserved protein Function unknown 110803069 Common xpt xanthine phosphoribosyltransferase CPR_1287 27 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110802466 Pathogen - hypothetical protein CPR_1920 1 None None None 110801887 Common - hypothetical protein CPR_1262 26 COG4760 COG4760, Predicted membrane protein Function unknown 110803420 Common - PRC-barrel domain, putative CPR_1731 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110802949 Common - hypothetical protein CPR_1533 4 None None None 110802103 Common - predicted Transcriptional regulator CPR_2206 25 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110802025 Common - IS1470, transposase CPR_0660 57 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110802104 Common - bacteriocin ABC transporter, bacteriocin-binding protein, putative CPR_1083 119 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110803186 Common - sensor histidine kinase CPR_1953 214 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110803877 Pathogen - hypothetical protein CPR_0937 1 None None None 110803411 Common - N-acetylmuramoyl-L-alanine amidase domain protein CPR_0113 97 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110803060 Common folC FolC bifunctional protein CPR_1885 221 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 110803020 Pathogen - hypothetical protein CPR_0944 1 None None None 110802507 Common - hydroxylamine reductase CPR_1120 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 110802650 Common - PTS system sorbose-specific iic component superfamily CPR_0398 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 110803132 Common - sporulation sigma factor SigK CPR_1738 212 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110802576 Common - spore maturation protein CPR_2542 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 110803776 Common - 5-formyltetrahydrofolate cyclo-ligase family protein CPR_2319 173 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 110803855 Common - hypothetical protein CPR_1208 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 110802003 Pathogen - putative lipoprotein CPR_0048 1 None None None 110802356 Common - glutamine transport protein glnQ CPR_2061 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110802813 Common - radical SAM domain protein CPR_1616 123 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 110802116 Common - hypothetical protein CPR_2538 10 COG3937 COG3937, Uncharacterized conserved protein Function unknown 110801701 Common - ISCpe4, transposase CPR_0198 43 None None None 110803114 Common citD citrate lyase subunit gamma CPR_1163 25 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 110803645 Common - pyruvate-flavodoxin oxidoreductase CPR_2032 121 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 110803696 Pathogen - probable transcription regulator CPR_0973 1 None None None 110802780 Common - ATP:guanido phosphotransferase CPR_2438 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 110803716 Common - HAD hydrolase, IIB family CPR_0492 75 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110803755 Common - rRNA methylase-like protein cspR CPR_1308 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 110803621 Common - DNA polymerase III, epsilon subunit, putative CPR_1638 7 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 110802842 Common pepF oligoendopeptidase F CPR_1439 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 110803171 Common - conserved hypothetical protein TIGR00150 CPR_2132 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 110801636 Common - spore-cortex-lytic enzyme, putative CPR_2348 30 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 110803427 Common - hypothetical protein CPR_2265 5 None None None 110803125 Common - hypothetical protein CPR_0076 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 110803992 Common - transferase, putative CPR_0192 12 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 110803476 Common rpsH 30S ribosomal protein S8 CPR_2385 219 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 110803292 Common - transcription regulator, member of GalR family regR CPR_0403 125 COG1609 PurR, Transcriptional regulators Transcription 110803751 Common glgD glucose-1-phosphate adenylyltransferase, GlgD subunit CPR_0087 126 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 110801542 Common - pts system, glucose-specific iia component CPR_0092 61 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 110803051 Common - Bacterial extracellular solute-binding proteins, family 5 superfamily CPR_2242 124 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110803924 Common hemL glutamate-1-semialdehyde aminotransferase CPR_1419 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 110802449 Common prtP cell wall-associated serine proteinase, lactocepin precursor CPR_0968 66 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110802593 Common - lactose operon transcriptional activator CPR_0749 128 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110803707 Common - cytidine/deoxycytidylate deaminase family protein CPR_0037 217 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 110802724 Pathogen - hypothetical protein CPR_0652 1 None None None 110803710 Common - spermidine/putrescine-binding periplasmic protein precursor CPR_1938 138 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110803537 Common - ISCpe2, transposase orfB CPR_0711 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803640 Common - oxidoreductase, NAD-binding CPR_1257 97 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110801476 Common - ISCpe4, transposase CPR_1479 45 None None None 110803827 Common - GTP pyrophosphokinase-like protein CPR_1575 27 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 110803319 Common - hypothetical protein CPR_0231 6 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 110802161 Common - hypothetical protein CPR_0011 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 110803820 Common - Bacterial membrane flanked domain family CPR_1491 5 COG3402 COG3402, Uncharacterized conserved protein Function unknown 110803156 Common - ATPase component of ABC transporter (two ATPase domains) CPR_0136 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110803288 Pathogen - hypothetical protein CPR_0792 1 None None None 110801588 Common - sodium:dicarboxylate symporter family protein CPR_1036 133 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110802854 Common dhaE glycerol dehydrase, gamma subunit CPR_1006 13 COG4910 PduE, Propanediol dehydratase, small subunit Secondary metabolites biosynthesis, transport, and catabolism 110801566 Common - spoVK domain protein CPR_1517 49 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110803541 Common xseA exodeoxyribonuclease VII large subunit CPR_1790 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 110801861 Pathogen - hypothetical protein CPR_0455 1 None None None 110801441 Common - transcriptional regulator, Fur family CPR_1445 176 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110803805 Pathogen - hypothetical protein CPR_1534 1 None None None 110801609 Common - chitinase B CPR_0949 7 None None None 110803281 Pathogen - BFD-like iron-sulfur cluster-binding protein CPR_0435 1 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110803720 Common - hypothetical protein CPR_0022 5 None None None 110801503 Common - transcriptional regulator, LacI family CPR_0416 129 COG1609 PurR, Transcriptional regulators Transcription 110803004 Common - probable membrane protein, putative CPR_2564 1 None None None 110801610 Common - Polysaccharide deacetylase family CPR_1582 74 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110801604 Common smpB SsrA-binding protein CPR_1291 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 110802756 Common - citrate lyase regulator, putative CPR_1160 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 110801482 Common - IS1470, transposase CPR_0628 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801600 Common - ATP-dependent DNA helicase, UvrD/REP family CPR_1591 95 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 110803520 Common - permease, putative domain protein CPR_0120 19 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110803811 Common folE GTP cyclohydrolase I CPR_1096 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 110802099 Common rpsQ 30S ribosomal protein S17 CPR_2390 224 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 110803197 Common - IS1470, transposase CPR_0712 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801537 Common - Predicted permease superfamily CPR_0044 89 COG0701 COG0701, Predicted permeases General function prediction only 110802442 Common - hypothetical protein CPR_1694 34 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 110803916 Common rnz ribonuclease Z CPR_1360 116 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 110801986 Common - nitrate ABC transporter ATP binding protein CPR_1464 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110801749 Common - hypothetical protein CPR_0799 2 None None None 110802010 Common - hypothetical protein CPR_0112 4 None None None 110802474 Common - hypothetical protein CPR_0005 12 None None None 110803315 Common engA GTP-binding protein EngA CPR_1726 238 COG1160 COG1160, Predicted GTPases General function prediction only 110803743 Common citN citrate/sodium symporter CPR_1168 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 110803265 Common - probable ABC exporter accessory factor for bacteriocin, putative CPR_0320 37 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110802916 Common - RNA methyltransferase, TrmH family CPR_1853 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110802567 Common - putative methyltransferase CPR_2555 133 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 110803149 Pathogen - hypothetical protein CPR_2552 1 None None None 110803413 Common - PTS system fructose IIA component superfamily CPR_0400 11 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 110802369 Common greA transcription elongation factor GreA CPR_1270 159 COG0782 GreA, Transcription elongation factor Transcription 110803730 Common - small, acid-soluble spore protein 1 CPR_2128 12 None None None 110802743 Common - DNA-binding response regulator CPR_0486 131 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 110803461 Common - sensory box histidine kinase CPR_1316 224 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110801847 Common - GntP family permease CPR_0845 89 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 110801625 Common spoIIAB anti-sigma F factor CPR_2021 22 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 110803627 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CPR_1389 244 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110803192 Common - hypothetical protein CPR_1010 40 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 110803046 Pathogen - hypothetical protein CPR_0851 1 None None None 110802519 Common - ATP-dependent DNA helicase PcrA, putative CPR_1226 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110803201 Pathogen - hypothetical protein CPR_1176 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110803297 Common sodF Mn/Fe superoxide dismutase CPR_1251 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 110802201 Common recR recombination protein RecR CPR_0057 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 110802331 Common rplS 50S ribosomal protein L19 CPR_1680 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 110801666 Common - cyclic nucleotide-binding domain protein CPR_2531 95 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110802030 Common - GTP-binding protein CPR_0106 190 COG1160 COG1160, Predicted GTPases General function prediction only 110802902 Common - hypothetical protein CPR_0897 2 None None None 110802516 Common - hypothetical protein CPR_0624 22 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 110802522 Common - hypothetical protein CPR_0277 6 None None None 110803166 Pathogen - hypothetical protein CPR_0038 1 None None None 110801918 Common - uncharacterized conserved protein, YABE CPR_1485 29 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 110802321 Common - stage 0 sporulation protein J CPR_2665 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 110803772 Common - conserved hypothetical protein TIGR00159 CPR_2346 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 110802641 Pathogen - hypothetical protein CPR_0893 1 None None None 110803404 Common - hypothetical protein CPR_1349 4 None None None 110802993 Common frr ribosome recycling factor CPR_1669 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 110803333 Common - exonuclease family protein CPR_2121 33 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 110803608 Common - hypothetical protein CPR_1644 79 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110802968 Pathogen - hypothetical protein CPR_1942 1 None None None 110803273 Pathogen - hypothetical protein CPR_1460 1 None None None 110803345 Common - oligopeptide ABC transporter, permease component CPR_2257 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110803694 Common - precorrin-2 dehydrogenase CPR_1423 18 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 110801891 Common - IS1470, transposase CPR_0321 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110803832 Common maf Maf-like protein CPR_2112 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 110802413 Pathogen - hypothetical protein CPR_0387 1 None None None 110801581 Common - glutamate synthase, beta subunit, putative CPR_2073 186 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110803468 Common - hypothetical protein CPR_0125 130 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110801663 Common - glutamate dehydrogenase CPR_1499 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 110802027 Common - hypothetical protein CPR_0051 3 None None None 110801599 Common - ABC transporter CPR_2368 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110802017 Common - lipoprotein, putative CPR_0885 2 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 110803952 Common - nucleoside recognition domain protein CPR_2588 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 110801826 Common - stage V sporulation protein D, spoVD, FtsI/pbp family CPR_1831 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110801644 Pathogen - hypothetical protein CPR_1158 1 None None None 110802723 Common sdhA L-serine dehydratase, iron-sulfur-dependent, alpha subunit CPR_2643 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110802223 Pathogen - hypothetical protein CPR_0190 1 None None None 110801679 Common - ISCpe2, transposase orfB CPR_0889 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803517 Pathogen - hypothetical protein CPR_0032 1 None None None 110802215 Common - molybdenum cofactor biosynthesis protein, putative CPR_1761 67 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110802532 Common - heme oxygenase 2 CPR_0203 24 COG5398 COG5398, Heme oxygenase Inorganic ion transport and metabolism 110802644 Common gidA putative FAD dependent oxidoreductase CPR_1768 14 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 110802391 Common - aminotransferase, class V CPR_0063 170 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 110803396 Common - DNA/RNA helicase, SNF2 CPR_0986 145 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 110802148 Pathogen - hypothetical protein CPR_1505 1 None None None 110803615 Common - acetyltransferase, GNAT family CPR_1933 2 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110801908 Common - DNA-binding response regulator CPR_0117 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110801530 Pathogen - hypothetical protein CPR_0233 1 None None None 110801654 Pathogen - hypothetical protein CPR_1457 1 None None None 110803141 Common - hypothetical protein CPR_0992 6 None None None 110801708 Common - ybaK/ebsC protein CPR_1356 113 COG2606 EbsC, Uncharacterized conserved protein Function unknown 110802718 Common - hypothetical protein CPR_2439 20 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 110803553 Common miaB tRNA-i(6)A37 thiotransferase enzyme MiaB CPR_1156 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110802932 Common - hypothetical protein CPR_0813 4 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110803052 Common cls cardiolipin synthetase CPR_0735 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110803183 Common argS arginyl-tRNA synthetase CPR_1633 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110802543 Common - hypothetical protein CPR_1883 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 110802769 Common cbiC precorrin-8X methylmutase CPR_1241 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 110802388 Common etfB electron transfer flavoprotein, beta subunit CPR_0303 151 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 110803770 Common - polysaccharide transporter protein, putative CPR_0464 39 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110802639 Common - transcriptional regulator, gntR family domain protein CPR_0369 100 COG2188 PhnF, Transcriptional regulators Transcription 110801794 Common - transcription regulator ArsR family-like protein yvbA CPR_0870 31 COG0640 ArsR, Predicted transcriptional regulators Transcription 110803210 Common - Predicted xylanase/chitin deacetilase CPR_0367 111 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110802755 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CPR_0334 207 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 110801753 Common ilvE branched-chain amino acid aminotransferase CPR_1501 202 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110802233 Common - Phosphofructokinase CPR_1203 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110802418 Common cdd cytidine deaminase CPR_1988 122 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 110802867 Common - hypothetical protein CPR_0356 2 None None None 110802372 Common def polypeptide deformylase CPR_1715 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 110803151 Common - transcriptional regulator, MarR family CPR_0493 39 COG1846 MarR, Transcriptional regulators Transcription 110802186 Common proA gamma-glutamyl phosphate reductase CPR_2582 201 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 110802273 Common - LPXTG-motif cell wall anchor domain protein CPR_0209 2 COG5386 COG5386, Cell surface protein Cell envelope biogenesis, outer membrane 110803568 Common - cell division protein, putative CPR_0292 106 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 110802440 Common - ABC transporter, ATP-binding protein CPR_0172 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 110803973 Common - peptidase, U32 family CPR_1848 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 110803306 Common - Holliday junction resolvase-like protein CPR_1748 177 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 110801493 Common - probable autolytic lysozyme, putative CPR_1311 29 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110803301 Common - metallopeptidase, family M24 CPR_2506 245 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110803527 Common - ABC transporter, permease protein, probable SP0913 , putative CPR_0837 11 None None None 110802610 Common - ribonucleotide-diphosphate reductase subunit alpha CPR_2356 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 110803865 Pathogen - putative lipoprotein CPR_1620 1 None None None 110802264 Common murC UDP-N-acetylmuramate--L-alanine ligase CPR_2502 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 110803515 Common - hypothetical protein CPR_0618 2 None None None 110803398 Common - rhomboid family protein CPR_1438 161 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110803465 Common map methionine aminopeptidase, type I CPR_2377 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 110801772 Common - hypothetical protein CPR_1959 6 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 110801554 Common - nitrite extrusion protein, putative CPR_2259 91 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110802308 Common comFC comFC protein CPR_2141 135 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 110802447 Common - hypothetical protein CPR_2243 1 None None None 110801901 Pathogen - hypothetical protein CPR_1121 1 None None None 110802808 Pathogen - general stress protein, putative CPR_0432 1 COG4980 GvpP, Gas vesicle protein General function prediction only 110802083 Common add adenosine deaminase CPR_2515 117 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 110802527 Common - transcription repressor of fructose operon fruR CPR_0552 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110803764 Common - hypothetical protein CPR_0745 3 None None None 110803198 Common - hypothetical protein CPR_0133 1 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 110801866 Common - GTP binding protein CPR_1927 229 COG2262 HflX, GTPases General function prediction only 110802676 Common eutD phosphotransacetylase CPR_1696 163 COG0280 Pta, Phosphotransacetylase Energy production and conversion 110801994 Common - peptide deformylase CPR_0741 2 None None None 110802632 Common - ATP:cob(I)alamin adenosyltransferase, putative CPR_1009 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 110802958 Common - AP endonuclease, family 2 protein CPR_1146 50 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 110802468 Common - hypothetical protein CPR_0610 6 None None None 110803507 Common glgC glucose-1-phosphate adenylyltransferase CPR_0086 224 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 110803768 Pathogen - hypothetical protein CPR_0801 1 None None None 110802918 Common - uncharacterized membrane protein CPR_1409 11 COG4684 COG4684, Predicted membrane protein Function unknown 110803736 Pathogen - hypothetical protein CPR_1065 1 None None None 110803652 Common modB molybdate ABC transporter, permease protein CPR_2053 171 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 110802617 Common - hypothetical protein CPR_2569 1 None None None 110802134 Common - uncharacterized membrane protein, putative CPR_0298 12 None None None 110801947 Common - conserved hypothetical protein TIGR00486 CPR_1972 156 COG0327 COG0327, Uncharacterized conserved protein Function unknown 110802824 Pathogen - ABC transporter, permease protein CPR_0438 1 None None None 110803853 Common - hypothetical protein CPR_1022 2 None None None 110803666 Common - hypothetical protein CPR_0306 4 None None None 110802534 Common - ABC transporter, permease protein, cysTW family, putative CPR_1465 144 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110801616 Common radC DNA repair protein RadC CPR_2111 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 110802294 Common - putative oxidoreductase CPR_2463 218 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110801895 Common nadE NAD synthetase CPR_1130 188 COG0171 NadE, NAD synthase Coenzyme metabolism 110801512 Common speD S-adenosylmethionine decarboxylase CPR_0513 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 110801691 Common thiH thiamine biosynthesis protein ThiH CPR_1570 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 110803512 Common - transporter, major facilitator family CPR_1574 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110802197 Common - polysaccharide deacetylase family protein CPR_1878 89 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110802409 Common - hypothetical protein CPR_0389 58 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110801889 Pathogen cpe enterotoxin Cpe CPR_0381 1 None None None 110802079 Common - polysaccharide biosynthesis protein, putative CPR_0590 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110803636 Common - sensor histidine kinase CPR_0487 22 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 110802123 Common rplW 50S ribosomal protein L23 CPR_2397 222 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 110801452 Common - cell wall surface anchor family protein CPR_0360 48 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 110803014 Common feoA feoA protein CPR_1630 48 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110803174 Common - ABC transporter, substrate-binding protein CPR_0540 76 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110803109 Common - metallo-beta-lactamase family protein CPR_0999 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 110802177 Pathogen - hypothetical protein CPR_0657 2 None None None 110802589 Common birA BirA bifunctional protein CPR_0663 207 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 110803451 Common - GGDEF/HD domain protein CPR_1530 178 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 110801510 Common xpt xanthine phosphoribosyltransferase CPR_0313 60 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110803843 Common - radical SAM domain protein CPR_1969 6 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 110801731 Common codY transcriptional repressor CodY CPR_1673 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 110801808 Common - hypothetical protein CPR_1544 1 None None None 110803591 Common - ISCpe2, transposase orfA CPR_0722 74 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803302 Pathogen - hypothetical protein CPR_1474 1 None None None 110802626 Common - Na+ driven multidrug efflux pump (mviN domain) CPR_1274 122 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110803084 Common cbiQ cobalt ABC transporter, permease protein CbiQ CPR_0184 76 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110803561 Common - sensory box protein/histidinol phosphate phosphatase family protein CPR_0788 187 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 110801974 Common - hypothetical protein CPR_0958 1 None None None 110802081 Common - transporter, auxin efflux carrier family CPR_0498 51 COG0679 COG0679, Predicted permeases General function prediction only 110802299 Common - transcriptional regulator, LacI family CPR_1340 127 COG1609 PurR, Transcriptional regulators Transcription 110803657 Common - MOSC domain, putative CPR_1759 30 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 110802319 Common recF recombination protein F CPR_0004 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 110801557 Common pyrE orotate phosphoribosyltransferase CPR_1196 155 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 110802314 Common - putative site-specific integrase-resolvase, degenerate CPR_0196 11 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 110801686 Common - pantothenate kinase CPR_2470 131 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 110803984 Common - adenylate cyclase CPR_1352 8 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 110802929 Pathogen - hypothetical protein CPR_0520 1 None None None 110802948 Common - hypothetical protein CPR_1317 113 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110803797 Common - nitroreductase family protein CPR_0997 81 COG0778 NfnB, Nitroreductase Energy production and conversion 110803740 Common arcA arginine deiminase CPR_0157 58 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 110801788 Common - hypothetical protein CPR_2028 1 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 110803597 Common rplP 50S ribosomal protein L16 CPR_2392 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 110803238 Common thiG thiazole synthase CPR_1571 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 110802848 Common - cobalt transport protein CbiN CPR_0183 41 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 110803530 Common - alkaline phosphatase-like protein CPR_1476 157 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110803144 Common glmS D-fructose-6-phosphate amidotransferase CPR_2322 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 110801495 Pathogen - hypothetical protein CPR_1072 1 None None None 110802397 Common - uncharacterized conserved protein, YbeA family CPR_2599 164 COG1576 COG1576, Uncharacterized conserved protein Function unknown 110802762 Common - hypothetical protein CPR_0224 2 None None None 110803567 Common - Penicillin binding protein transpeptidase domain protein CPR_1739 197 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110802748 Common - Cobalt transport protein superfamily CPR_1554 62 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110803942 Common - serine/threonine protein kinase CPR_1709 167 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 110802392 Common - hypothetical protein CPR_1071 15 None None None 110803062 Common - hypothetical protein CPR_0121 2 None None None 110803184 Common - transcriptional regulator, MarR family CPR_0509 1 COG1846 MarR, Transcriptional regulators Transcription 110803686 Common - HAD hydrolase, IIB family CPR_1309 143 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110802799 Common - hypothetical protein CPR_1916 1 None None None 110803253 Common - hydroxylamine reductase CPR_2587 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 110803548 Common - SACPA operon antiterminator (sacT) CPR_0091 30 COG3711 BglG, Transcriptional antiterminator Transcription 110802864 Common - transcriptional regulator, AraC family CPR_0208 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110801785 Common - transcriptional regulator, MarR family CPR_1135 55 COG1846 MarR, Transcriptional regulators Transcription 110802108 Common - tetratricopeptide repeat protein CPR_1955 102 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 110802920 Common psd phosphatidylserine decarboxylase CPR_0033 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 110803242 Common colA microbial collagenase CPR_0162 37 COG3291 COG3291, FOG: PKD repeat General function prediction only 110802437 Pathogen - hypothetical protein CPR_0702 1 None None None 110802007 Common glyA serine hydroxymethyltransferase CPR_1895 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 110802694 Common - cinnamoyl ester hydrolase CPR_0720 59 COG1733 COG1733, Predicted transcriptional regulators Transcription 110802578 Common - hypothetical protein CPR_1285 19 None None None 110803447 Pathogen - hypothetical protein CPR_0963 1 None None None 110801775 Common - sortase family protein CPR_0479 5 COG4509 COG4509, Uncharacterized protein conserved in bacteria Function unknown 110802065 Common - isochorismatase family protein CPR_0555 38 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110803249 Common - hypothetical protein CPR_1267 30 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 110803554 Common - DedA family protein CPR_0543 124 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110801673 Common - redox-sensing transcriptional repressor Rex CPR_2288 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 110802557 Common - d-galactose-binding periplasmic protein precursor CPR_1341 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110802045 Common cfa cyclopropane-fatty-acyl-phospholipid synthase CPR_1123 139 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110802687 Pathogen - hypothetical protein CPR_1368 1 None None None 110802154 Common - permease, putative domain protein CPR_1980 3 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 110802101 Common - hypothetical protein CPR_1823 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 110803385 Common - hypothetical protein CPR_0201 18 None None None 110803481 Pathogen - hypothetical protein CPR_0116 1 COG4640 COG4640, Predicted membrane protein Function unknown 110802969 Common metC cystathionine beta-lyase CPR_0165 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110802936 Common pyk pyruvate kinase CPR_0342 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110803494 Common spoVAD stage V sporulation protein AD CPR_2018 15 None None None 110802457 Common galE UDP-glucose 4-epimerase CPR_0273 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 110803650 Common - pullulanase precursor CPR_1558 155 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 110801925 Common - MutT/nudix family protein CPR_2640 22 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110803673 Common dnaX DNA polymerase III subunits gamma and tau CPR_0055 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 110803077 Common - galactose/methyl galaxtoside transporter ATP-binding protein CPR_1342 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110802257 Common - transcriptional regulator, GntR family/aminotransferase CPR_0347 202 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110802975 Common folA dihydrofolate reductase CPR_0054 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 110802059 Common - teichoic acid translocation ATP-binding protein CPR_0255 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110803475 Common - hypothetical protein CPR_2419 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 110803322 Common - hypothetical protein CPR_0170 37 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 110803359 Common - hypothetical protein CPR_0058 3 None None None 110802429 Pathogen - hypothetical protein CPR_0021 1 None None None 110802250 Common cbiM cobalt transport protein CbiM CPR_0182 59 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 110803623 Common - hypothetical protein CPR_1415 28 COG3819 COG3819, Predicted membrane protein Function unknown 110803321 Common - membrane carboxypeptidase mrcB CPR_1930 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 110803373 Common - undecaprenyl diphosphate synthase, putative CPR_1528 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110802970 Pathogen - hypothetical protein CPR_1195 1 None None None 110802831 Common asd aspartate-semialdehyde dehydrogenase CPR_1871 229 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 110802898 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase CPR_1913 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 110802050 Common - aminotransferase family protein CPR_1365 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110801859 Pathogen - hypothetical protein CPR_0763 1 None None None 110801951 Common - putative fibronectin-binding protein CPR_0718 7 None None None 110803486 Common - scdA protein, putative CPR_0753 39 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 110802715 Common - hypothetical protein CPR_0740 37 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 110802194 Common - membrane protein CPR_2546 183 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 110802422 Common - aldehyde-alcohol dehydrogenase [includes: alcohol CPR_2540 214 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110803049 Common - fructokinase CPR_1510 178 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110801717 Common - DNA-binding response regulator CPR_2359 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110802962 Common - hypothetical protein CPR_1305 8 None None None 110801816 Pathogen - hypothetical protein CPR_1805 1 None None None 110801870 Common aspB aspartate aminotransferase CPR_1642 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110803810 Common - phage shock protein A CPR_1542 70 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 110802097 Common - ISCpe2, transposase orfB CPR_1565 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801931 Common hrcA heat-inducible transcription repressor CPR_2007 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 110802888 Common - ABC transporter domain protein CPR_2340 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110803535 Common uppS undecaprenyl diphosphate synthase CPR_1668 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110801945 Common - glycosytransferase, putative CPR_0459 228 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110802591 Common rpsN 30S ribosomal protein S14 CPR_2386 187 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 110802819 Common - DNA helicase II related protein, putative CPR_0350 10 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 110803803 Common folD folD bifunctional protein CPR_1791 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 110803890 Common - hypothetical protein CPR_1392 6 COG4640 COG4640, Predicted membrane protein Function unknown 110801460 Common - hypothetical protein CPR_2339 17 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 110801893 Pathogen - hypothetical protein CPR_0843 1 None None None 110801791 Common - ISCpe7, transposase CPR_0947 52 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803825 Common - zinc-dependent hydrolase, putative CPR_2441 63 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110802856 Common - PTS system, IID component CPR_0399 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 110802479 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CPR_1646 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110801953 Common ftsA cell division protein FtsA CPR_1736 168 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 110803926 Common - hypothetical protein CPR_0324 44 COG1808 COG1808, Predicted membrane protein Function unknown 110803286 Common - sensor histidine kinase CPR_0831 183 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802767 Pathogen - hypothetical protein CPR_1354 1 COG5460 COG5460, Uncharacterized conserved protein Function unknown 110801576 Common - glycosyl transferase, group 2 family protein CPR_0461 16 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110801657 Common - DJ-1 family protein CPR_2038 124 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 110803522 Common sleC spore cortex-lytic enzyme SleC CPR_2566 2 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 110801484 Common - transporter, putative CPR_0036 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 110801719 Common asnC asparaginyl-tRNA synthetase CPR_2509 221 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110801564 Common - hypothetical protein CPR_0636 14 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 110802980 Common rpsL 30S ribosomal protein S12 CPR_2405 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 110801747 Common mutL DNA mismatch repair protein CPR_1172 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 110802057 Common iadA isoaspartyl dipeptidase CPR_2351 31 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110803223 Common - hypothetical protein CPR_0820 81 COG1511 COG1511, Predicted membrane protein Function unknown 110801744 Common minC septum formation inhibitor CPR_2106 112 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 110801602 Common - hypothetical protein CPR_0894 3 None None None 110801872 Common - mutator MutT protein, putative CPR_0898 162 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110802088 Common - PAP2 family protein CPR_0783 63 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 110801534 Common gyrA DNA gyrase subunit A CPR_0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110803009 Common minE cell division topological specificity factor MinE CPR_2104 39 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 110803745 Common - IS1469, transposase CPR_0382 70 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801467 Common atpD F0F1 ATP synthase subunit beta CPR_2162 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 110802758 Common cls cardiolipin synthetase CPR_1418 156 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110803006 Common - histidinol phosphatase, putative CPR_1040 32 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110803914 Common - ABC transporter domain protein CPR_1555 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110802661 Common dhaB glycerol dehydratase, alpha subunit CPR_1004 13 COG4909 PduC, Propanediol dehydratase, large subunit Secondary metabolites biosynthesis, transport, and catabolism 110802668 Common - ABC transporter domain protein CPR_0119 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110801529 Common - LicD family protein CPR_0589 16 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 110802450 Pathogen - hypothetical protein CPR_1018 1 None None None 110801965 Common - single-strand DNA-binding protein CPR_1877 7 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110803094 Common mreC rod shape-determining protein MreC CPR_2109 141 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 110802524 Common - S4 domain protein CPR_0003 41 COG2501 COG2501, Uncharacterized conserved protein Function unknown 110802505 Common - transcriptional regulator, TetR family CPR_0361 14 COG1309 AcrR, Transcriptional regulator Transcription 110802070 Common - Carbonic anhydrase CPR_0410 40 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 110803160 Common - hypothetical protein CPR_0097 1 None None None 110803208 Common glmU UDP-N-acetylglucosamine pyrophosphorylase CPR_2499 239 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 110803990 Pathogen - hypothetical protein CPR_0629 1 None None None 110801508 Common gap glyceraldehyde-3-phosphate dehydrogenase, type I CPR_1301 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110802659 Common - putative lipoprotein CPR_2522 1 None None None 110803642 Common adk adenylate kinase CPR_2378 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 110803022 Common hup DNA-binding protein HU CPR_2488 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 110803154 Pathogen - hypothetical protein CPR_2545 1 None None None 110803625 Common accB acetyl-CoA carboxylase, biotin carboxyl carrier protein CPR_1140 189 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 110803960 Common - hypothetical protein CPR_2597 9 COG1950 COG1950, Predicted membrane protein Function unknown 110802690 Common - hypothetical protein CPR_2530 31 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 110803969 Common - pyrimidine nucleoside transporter CPR_1281 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 110803698 Common - molybdenum cofactor synthesis protein CPR_2055 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 110803130 Common - hypothetical protein CPR_0180 1 None None None 110803757 Common - MATE efflux family protein CPR_2544 137 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110801777 Common pyrC dihydroorotase, multifunctional complex type CPR_1200 218 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110803955 Common feoA ferrous iron repressor CPR_0972 58 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110801936 Common polC DNA polymerase III PolC CPR_1663 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 110801938 Pathogen - hypothetical protein CPR_1220 1 None None None 110802355 Pathogen - hypothetical protein CPR_1809 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110802460 Common - hypothetical protein CPR_0242 4 None None None 110803647 Common ldh L-lactate dehydrogenase CPR_0102 165 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 110802184 Common spoVT stage V sprulation protein T CPR_2491 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110801703 Pathogen - hypothetical protein CPR_0800 1 None None None 110802810 Common - hypothetical protein CPR_1568 2 None None None 110803070 Common - antibiotic ABC transporter, ATP-binding protein CPR_0053 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110803919 Common - co-chaperone GrpE, putative CPR_0237 11 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 110801729 Pathogen - hypothetical protein CPR_0582 2 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 110803415 Common - ribosomal large subunit pseudouridine synthase f CPR_2299 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110802839 Common - conserved hypothetical protein TIGR02336 CPR_0537 4 None None None 110802782 Common - hypothetical protein CPR_1229 1 None None None 110802043 Common punA purine nucleoside phosphorylase CPR_2504 146 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110802341 Common - hypothetical protein CPR_1838 21 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110801592 Common - signal peptidase type IV CPR_2273 119 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110801824 Common - PTS system, trehalose-specific IIB component CPR_0525 41 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110803610 Common malQ 4-alpha-glucanotransferase CPR_2333 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 110803839 Common - ethanolamine utilization protein euth CPR_2198 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 110803179 Common - hypothetical protein CPR_0045 2 COG3689 COG3689, Predicted membrane protein Function unknown 110802036 Common glmM phosphoglucosamine mutase CPR_2324 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110803445 Common - hypothetical protein CPR_0073 1 None None None 110803928 Common - hypothetical protein CPR_0013 5 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 110801642 Common - amino acid ABC transporter (binding protein) CPR_1324 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110802242 Common - N-acetylmuramoyl-l-alanine amidase, putative CPR_0529 26 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 110802029 Common - hemolysin III CPR_1453 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 110802624 Common - ISCpe2, transposase orfB CPR_0409 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802019 Common - Penicillin binding protein transpeptidase domain protein CPR_0332 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110802721 Common - Bacterial extracellular solute-binding protein domain protein CPR_0072 45 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110803290 Common - protein phosphatase 2C family protein CPR_1710 136 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 110802985 Common - ferredoxin--NADP(+) reductase subunit alpha CPR_1264 88 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110802934 Common - amino acid permease family protein CPR_1034 54 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110802225 Common pgk phosphoglycerate kinase CPR_1300 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 110802545 Pathogen - hypothetical protein CPR_0650 1 None None None 110803840 Common - peptidase, M23/M37 family protein CPR_1587 193 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 110803363 Pathogen - hypothetical protein CPR_0553 1 None None None 110803617 Common thiC thiamine biosynthesis protein ThiC CPR_0668 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 110802775 Pathogen - transport protein USO1, putative CPR_0338 2 None None None 110803684 Pathogen - hypothetical protein CPR_1000 1 None None None 110803379 Pathogen - lipoprotein, putative CPR_1289 1 None None None 110801547 Common rph ribonuclease PH CPR_2240 205 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 110803054 Common - transcriptional regulator, MarR family CPR_1283 90 COG1846 MarR, Transcriptional regulators Transcription 110803838 Common - dolichyl-phosphate-mannose-protein mannosyltransferase family protein CPR_0954 8 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 161763552 Common rpmG 50S ribosomal protein L33 CPR_2415 85 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 110802159 Common - Protein of unknown function DUF262 family CPR_2122 75 COG1479 COG1479, Uncharacterized conserved protein Function unknown 110802362 Common - hypothetical protein CPR_2280 2 None None None 110802553 Common - endonuclease/exonuclease/phosphatase family protein CPR_0419 5 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 110801656 Common - polysaccharide lyase, family 8 CPR_0390 15 None None None 110803895 Common narB nitrate reductase electron transfer subunit CPR_1766 156 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 110802371 Common - stage III sporulation protein AC CPR_1799 15 None None None 110803586 Common - hypothetical protein CPR_1430 13 None None None 110803181 Common - iron compound ABC transporter, iron-binding protein CPR_1115 178 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110802536 Common - licC protein CPR_0596 177 COG4750 LicC, CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes Cell envelope biogenesis, outer membrane 110802565 Common - response regulator CPR_0830 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110801627 Common - ISCpe2, transposase orfB CPR_1031 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803370 Common - degV family protein CPR_0030 56 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110803034 Common - carboxyl-terminal protease CPR_0293 187 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110802327 Common - Pyridine nucleotide-disulphide oxidoreductase CPR_0984 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110802249 Common - hypothetical protein CPR_1500 1 None None None 110803267 Common kduD 2-deoxy-D-gluconate 3-dehydrogenase CPR_0392 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110803732 Common - glucose kinase CPR_0098 178 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110802510 Common - hypothetical protein CPR_1247 6 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 110802366 Common - Alpha amylase, catalytic domain subfamily, putative CPR_0948 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110801668 Common - ABC transporter domain protein CPR_1449 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110802634 Common - Peptidase family T4 superfamily CPR_1410 53 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110802869 Common - hypothetical protein CPR_0412 4 None None None 110801519 Pathogen - hypothetical protein CPR_0787 1 None None None 110801448 Common - surface layer protein B CPR_0279 15 COG3291 COG3291, FOG: PKD repeat General function prediction only 110803219 Common - hypothetical protein CPR_0177 29 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 110802716 Common - hypothetical protein CPR_0573 35 COG2510 COG2510, Predicted membrane protein Function unknown 110803934 Pathogen - hypothetical protein CPR_0316 1 None None None 110802706 Common - hypothetical protein CPR_1660 43 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 110802358 Common - RNAse H family protein CPR_1436 16 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 110803871 Common - galactose mutarotase related enzyme CPR_0270 44 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 110803122 Common - hypothetical protein CPR_0223 95 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110803295 Pathogen - hypothetical protein CPR_1125 1 None None None 110803725 Common - NAD(+)/NADH kinase CPR_1785 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 110803335 Common - hypothetical protein CPR_0730 6 None None None 110803391 Common sdhB L-serine dehydratase, iron-sulfur-dependent, beta subunit CPR_1057 96 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110803083 Common - hypothetical protein CPR_1771 1 None None None 110802472 Common - hypothetical protein CPR_1210 12 COG4905 COG4905, Predicted membrane protein Function unknown 110803025 Common - mutT/nudix family protein, truncation CPR_1029 22 None None None 110803262 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein CPR_1917 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110803275 Common - hypothetical protein CPR_1561 25 COG2966 COG2966, Uncharacterized conserved protein Function unknown 110802878 Common - N-terminal truncated of elongation factor Ts CPR_1985 2 None None None 110801838 Common - alpha-N-acetylglucosaminidase family protein CPR_0850 38 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110803343 Common - nucleotidyltransferase domain protein CPR_1925 1 None None None 110801911 Common cobQ cobyric acid synthase CobQ CPR_1119 156 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 110802608 Common - hypothetical protein CPR_2058 3 COG5578 COG5578, Predicted integral membrane protein Function unknown 110802913 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CPR_2668 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 110801455 Common - hypothetical protein CPR_1686 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 110801638 Common - disulfide bond formation protein a precursor, putative CPR_2547 8 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 110803817 Common - hypothetical protein CPR_1825 18 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 110801699 Common - sensor histidine kinase CPR_0500 108 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 110803921 Pathogen - hypothetical protein CPR_0587 1 None None None 110803173 Common - hypothetical protein CPR_2309 2 None None None 110801478 Common yajC preprotein translocase subunit YajC CPR_1911 33 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 110803406 Pathogen yajC preprotein translocase, YajC subunit CPR_0401 2 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 110802991 Common - putative endoribonuclease L-PSP CPR_1089 195 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110803718 Common clpX ATP-dependent protease ATP-binding subunit CPR_1384 232 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 110803435 Common - stage III sporulation protein AE CPR_1797 15 None None None 110802041 Common - putative iron transporter CPR_0210 2 COG5386 COG5386, Cell surface protein Cell envelope biogenesis, outer membrane 110801711 Common - small basic protein sbp CPR_1824 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 110803816 Common - pseudouridine synthase CPR_1818 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110802703 Common - tRNA 2-selenouridine synthase CPR_2041 65 COG2603 COG2603, Predicted ATPase General function prediction only 110801718 Common aroQ 3-dehydroquinate dehydratase CPR_0695 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 110803729 Common - amino acid (glutamine) ABC transporter, permease protein-like protein lin1851 CPR_1325 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110801454 Common thiE thiamine-phosphate pyrophosphorylase CPR_1336 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110803392 Common cysS cysteinyl-tRNA synthetase CPR_2424 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801914 Pathogen - hypothetical protein CPR_0912 1 None None None 110803041 Common - transcriptional regulator, RpiR family CPR_1149 97 COG1737 RpiR, Transcriptional regulators Transcription 110803176 Common - aspartate aminotransferase CPR_0701 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110801923 Pathogen - hypothetical protein CPR_0194 1 None None None 110803205 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CPR_2426 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 110802963 Common aroF 3-deoxy-7-phosphoheptulonate synthase CPR_0688 187 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 110803233 Common - lrgA family protein CPR_1947 41 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 110803958 Common - trehalose operon transcriptional repressor CPR_0527 122 COG2188 PhnF, Transcriptional regulators Transcription 110802990 Common - hypothetical protein CPR_0976 2 None None None 110802213 Common ispA geranyltranstransferase CPR_1788 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 110802364 Common - peptidase, M50 family CPR_2101 39 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110802173 Common - ISCpe2, transposase orfB CPR_0408 2 None None None 110801630 Pathogen - hypothetical protein CPR_1269 1 None None None 110803408 Common spoIIGA Sporulation factor SpoIIGA CPR_1734 9 None None None 110801479 Common thiS thiamine biosynthesis protein ThiS CPR_1573 14 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 110803841 Common - HesB-related selenoprotein CPR_0641 1 COG0316 IscA, Uncharacterized conserved protein Function unknown 110802951 Common citC citrate lyase ligase CPR_1162 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 110803375 Common - glycogen debranching enzyme, archaeal type, putative CPR_2331 37 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 110802508 Pathogen - hypothetical protein CPR_1087 1 None None None 110801720 Common cphB cyanophycinase CPR_2188 35 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 110803800 Common carB carbamoyl phosphate synthase large subunit CPR_2576 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 110803278 Common - EAL domain protein CPR_0868 174 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110802206 Common - Ser/Thr protein phosphatase family protein CPR_2507 95 COG0622 COG0622, Predicted phosphoesterase General function prediction only 110801590 Common - 3-oxoacyl-[acyl-carrier protein] reductase CPR_0344 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110802144 Common - hypothetical protein CPR_1860 3 None None None 110802779 Common - hypothetical protein CPR_1452 8 None None None 110802906 Common - hypothetical protein CPR_0623 35 COG0714 COG0714, MoxR-like ATPases General function prediction only 110803884 Common - probable flavoprotein, YhiN family CPR_1150 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 110801776 Common - thiamine monophosphate synthase family protein CPR_1569 82 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110802481 Pathogen - hypothetical protein CPR_0762 1 None None None 110801651 Common proS prolyl-tRNA synthetase CPR_2425 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803400 Common - ABC transporter domain protein CPR_0437 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110801815 Pathogen - hypothetical protein CPR_0834 2 None None None 110801796 Pathogen - hypothetical protein CPR_0653 1 None None None 110802246 Common atpC ATP synthase F1, epsilon subunit CPR_2161 117 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 110803701 Common - hypothetical protein CPR_1250 6 None None None 110801622 Common spo0A Spo0A protein CPR_1781 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110802681 Common - Alpha-glucosidases, family 31 of glycosyl hydrolases CPR_2334 78 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 110802862 Common - hypothetical protein CPR_2483 62 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 110802514 Common - membrane protein containing HD superfamily hydrolase domain CPR_1991 57 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 110802334 Common - hypothetical protein CPR_0857 15 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110802736 Common citG triphosphoribosyl-dephospho-CoA synthase CPR_1161 47 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 110802394 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein CPR_1977 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 110803837 Common - cellobiose phosphotransferase enzyme IIC component-like protein lin2832 CPR_2601 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 110801629 Common - hypothetical protein CPR_1277 1 None None None 110801535 Common - translation-associated GTPase CPR_1835 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 110802688 Common leuS leucyl-tRNA synthetase CPR_0645 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803037 Common - ISCpe7, transposase CPR_0982 53 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803936 Common - hypothetical protein CPR_1967 20 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 110801647 Common - hypothetical protein CPR_0405 8 COG4269 COG4269, Predicted membrane protein Function unknown 110802855 Common spoVE stage V sporulation protein E CPR_1827 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110803794 Common cdsA phosphatidate cytidylyltransferase CPR_1667 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 110802580 Common - probable reticuline oxidase CPR_0404 43 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110803293 Pathogen - hypothetical protein CPR_0646 1 None None None 110802731 Common - TrkA-C domain protein CPR_1361 11 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 110802622 Common - PP-loop family protein CPR_1477 157 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110802998 Common - hypothetical protein CPR_1260 2 None None None 110801546 Common rpmJ ribosomal protein L36 CPR_2374 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 110802285 Common - hypothetical protein CPR_1897 29 COG3610 COG3610, Uncharacterized conserved protein Function unknown 110802671 Common - glycine betaine/carnitine/choline transport ATP-binding protein CPR_0521 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 110803438 Common - glycosyl transferase, group 2 family protein domain protein CPR_0706 207 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110802770 Pathogen - hypothetical protein CPR_2153 1 None None None 110802227 Pathogen - acetyltransferase, GNAT family CPR_0975 1 None None None 110801952 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CPR_1450 23 COG0756 Dut, dUTPase Nucleotide transport and metabolism 110803099 Common - hypothetical protein CPR_0680 43 COG3304 COG3304, Predicted membrane protein Function unknown 110802761 Common - cation efflux family protein CPR_0983 188 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110803364 Common - ISCpe5, transposase CPR_0767 7 None None None 110801549 Common - hypothetical protein CPR_1623 5 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110802459 Common - CBS domain protein CPR_1984 22 COG0517 COG0517, FOG: CBS domain General function prediction only 110802493 Common - ribose operon repressor, putative CPR_0903 124 COG1609 PurR, Transcriptional regulators Transcription 110801608 Common fmt methionyl-tRNA formyltransferase CPR_1714 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 110802571 Common bcn bacteriocin CPR_0631 3 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 110802884 Common iscS cysteine desulfurase CPR_1755 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 110803161 Common etfA electron transfer flavoprotein, alpha subunit CPR_0304 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 110802346 Common - hypothetical protein CPR_1879 4 None None None 110802086 Common - type IV pilus assembly protein PilM CPR_2269 74 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 110803430 Common - membrane proteins-like protein lmo0908, putative CPR_1880 189 COG0628 PerM, Predicted permease General function prediction only 110801935 Common ppdA Prepilin peptidase dependent protein A precursor CPR_2274 4 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 110803079 Pathogen - hypothetical protein CPR_1455 1 None None None 110802478 Common - regulatory protein pfoR CPR_0152 10 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 110803136 Common - NADH-dependent butanol dehydrogenase a CPR_0842 170 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 110802399 Common scpB segregation and condensation protein B CPR_1773 157 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 110802564 Common nagE PTS system, N-acetylglucosamine-specific IIBC component CPR_0935 51 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110801522 Common - hypothetical protein CPR_0838 2 None None None 110802207 Common - nucleotidyltransferase family protein CPR_1222 6 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110802471 Common - hypothetical protein CPR_1527 9 COG4129 COG4129, Predicted membrane protein Function unknown 110803251 Common - modification methylase, HemK family CPR_2177 215 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 110802012 Pathogen - hypothetical protein CPR_1588 1 None None None 110802054 Common - protein T24A6.7 CPR_0151 29 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 110801834 Common cobS cobalamin 5'-phosphate synthase CPR_1110 133 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 110803003 Common - IS1470, transposase CPR_1373 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801526 Common - bacteriocin ABC transporter, putative CPR_0656 93 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110803813 Common - hypothetical protein CPR_2099 42 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 110801949 Common - hypothetical protein CPR_2068 3 None None None 110802382 Pathogen - hypothetical protein CPR_1780 1 None None None 110803123 Pathogen - hypothetical protein CPR_1586 1 None None None 110802664 Common - sugar transport system (permease) (binding protein dependent transporter) CPR_2051 141 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 110802071 Common - peptidase, putative, truncation CPR_1064 23 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 110803024 Common - hypothetical protein CPR_1414 27 COG3817 COG3817, Predicted membrane protein Function unknown 110801985 Common - hypothetical protein CPR_1659 19 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 110803285 Common galU UTP-glucose-1-phosphate uridylyltransferase CPR_0465 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110803066 Common - membrane-associated zinc metalloprotease, putative CPR_1665 220 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 110801898 Common - phosphoribosylformylglycinamidine synthase CPR_0669 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 110803158 Common ulaA ascorbate-specific PTS system enzyme IIC CPR_0491 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 110802128 Common - heparinase II/III-like protein CPR_0460 28 None None None 110801584 Common - ISCpe2, transposase orfB CPR_0472 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802454 Common - hypothetical protein CPR_0301 159 COG2186 FadR, Transcriptional regulators Transcription 110802152 Common glpE glycerol uptake facilitator protein CPR_1001 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 110803101 Common map methionine aminopeptidase, type I CPR_1375 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 110803271 Common - MutS domain protein CPR_0300 197 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110802875 Common - transcriptional regulator, GntR family CPR_2432 138 COG2188 PhnF, Transcriptional regulators Transcription 110801446 Common cobM precorrin-4 C11-methyltransferase CPR_1236 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 110803920 Pathogen - hypothetical protein CPR_0426 1 None None None 110803759 Common - ROK family protein CPR_0178 148 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110802094 Common - rubredoxin CPR_0768 121 COG1773 COG1773, Rubredoxin Energy production and conversion 110801813 Common - 1-phosphofructokinase CPR_0551 99 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 110802981 Common - diacylglycerol kinase/PAP2 family protein CPR_1989 102 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 110801742 Common - conserved hypothetical protein TIGR00278 CPR_2672 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 110803662 Common manA mannose-6-phosphate isomerase, class I CPR_1205 48 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 110803738 Common - ISCpe2, transposase orfA CPR_0406 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803505 Common - HesA/MoeB/ThiF family protein CPR_0067 177 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 110801507 Pathogen - hypothetical protein CPR_0154 1 None None None 110801768 Common - tetrapyrrole methylase family protein CPR_0267 213 COG0313 COG0313, Predicted methyltransferases General function prediction only 110802656 Common - sensory box histidine kinase CPR_0195 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110803142 Pathogen - hypothetical protein CPR_1396 1 None None None 110802858 Common purM phosphoribosylaminoimidazole synthetase CPR_0673 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 110801662 Common - stage II sporulation protein P CPR_2012 15 None None None 110803526 Common - amino acid permease yshA CPR_1212 85 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110803090 Common - peptidase family protein CPR_2191 11 None None None 110803905 Common - CAAX amino terminal protease family protein CPR_0129 26 None None None 110803911 Common - ISCpe5, transposase CPR_0685 6 None None None 110803824 Common rplK 50S ribosomal protein L11 CPR_2412 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 110802274 Common - two-component response regulator CPR_0501 222 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 110803891 Common - helicase, putative CPR_0566 61 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 110803459 Common - conserved hypothetical protein TIGR00046 CPR_1998 202 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 110803861 Pathogen - lipoprotein, putative CPR_0911 1 None None None 110802629 Common pflA pyruvate formate-lyase activating enzyme CPR_1170 110 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110802423 Common - hypothetical protein CPR_1333 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 110801842 Common - uracil permease CPR_1232 136 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110802293 Pathogen - hypothetical protein CPR_1596 1 None None None 110802157 Common - hypothetical protein CPR_0239 1 None None None 110802950 Common - Helix-turn-helix domain protein CPR_1434 27 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 110801864 Common - sulfite/nitrite reductase, putative CPR_0434 154 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110801806 Common - CBS domain/MgtE intracellular domain protein CPR_1323 178 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 110802834 Common - putative translaldolase CPR_0683 165 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 110803324 Common - iron compound ABC transporter, permease protein CPR_0780 190 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 110803464 Common - stage II sporulation protein R CPR_2185 15 None None None 110803145 Pathogen - hypothetical protein CPR_1080 1 None None None 110802944 Common - hydrogenase nickel insertion protein HypA CPR_0821 2 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 110801489 Common - putative iron-sulfur cluster binding protein CPR_1320 131 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 110803687 Common rluB ribosomal large subunit pseudouridine synthase B CPR_1147 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110801853 Common - glutamine amidotransferase, CobB/CobQ family CPR_1207 56 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 110803734 Common cax calcium/proton exchanger CPR_1366 60 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 110803665 Pathogen - hypothetical protein CPR_1228 1 None None None 110802436 Common - sialidase CPR_0877 18 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 110803490 Common - transcriptional regulator, AsnC family CPR_0700 87 COG1522 Lrp, Transcriptional regulators Transcription 110802166 Common - rubredoxin/flavodoxin/oxidoreductase CPR_1091 208 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110802181 Common - hypothetical protein CPR_1417 18 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 110801676 Common rplN 50S ribosomal protein L14 CPR_2389 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 110803228 Common - PTS system, IIBC component CPR_0418 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110801836 Common sigE sporulation sigma factor SigE CPR_1733 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110803498 Pathogen - hypothetical protein CPR_0950 1 None None None 110803582 Common yyaC putative sporulation protein YyaC CPR_2154 14 None None None 110801858 Common recA recombinase A CPR_1645 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 110803957 Common - HD domain protein CPR_2091 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 110803670 Common - phosphate permease CPR_0549 171 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 110803218 Common - ISCpe4, transposase CPR_0746 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802046 Common - lactococcin g processing and transport ATP-binding protein CPR_0318 83 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 110802704 Common metK S-adenosylmethionine synthetase CPR_2145 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 110803081 Common - hypothetical protein CPR_1593 3 None None None 110802251 Common valS valyl-tRNA synthetase CPR_1886 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803879 Common galK galactokinase CPR_1345 108 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 110803575 Common - ABC-type iron (III) transport system, ATPase component CPR_1442 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 110802909 Common - radical SAM domain protein protein CPR_1909 112 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 110801697 Common - ATP-dependent helicase, putative CPR_1217 82 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 110803724 Common - ATP-dependent protease CPR_2649 242 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110802787 Common - Ser/Thr protein phosphatase family CPR_2127 101 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 110803981 Common - acyl carrier protein phosphodiesterase CPR_0777 100 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 110802915 Common secY preprotein translocase subunit SecY CPR_2379 229 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 110802150 Common - hypothetical protein CPR_0428 12 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 110802230 Pathogen - hypothetical protein CPR_0415 1 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 110801757 Pathogen - hypothetical protein CPR_0186 1 None None None 110803538 Common - sugar hydrolase CPR_1405 49 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 110803443 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CPR_1173 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 110803502 Common clpC negative regulator of genetic competence MecB/ClpC CPR_2437 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 110803675 Common - Single-strand binding protein family CPR_0274 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110802495 Common - hypothetical protein CPR_1957 3 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 110802038 Common - Orn/Lys/Arg decarboxylase CPR_2448 80 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 110801561 Common - ISCpe2, transposase orfB CPR_0723 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801594 Common - radical SAM domain protein CPR_1063 59 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 110802558 Common - ISCpe2, transposase orfA CPR_0127 9 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801761 Common - acetyltransferase, GNAT family CPR_1363 22 COG0456 RimI, Acetyltransferases General function prediction only 110802798 Common spoIIIAF stage III sporulation protein AF CPR_1796 4 None None None 110802733 Pathogen - hypothetical protein CPR_1126 1 None None None 110802791 Common - stage IV sporulation protein, putative CPR_1992 14 None None None 110802100 Common - membrane protein CPR_0322 57 COG2510 COG2510, Predicted membrane protein Function unknown 110803704 Common - NupC family protein CPR_2505 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 110802987 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase CPR_0671 195 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 110803531 Common deoB phosphopentomutase CPR_0371 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 110803691 Common - DNA-binding response regulator CPR_1891 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110803601 Common truA tRNA pseudouridine synthase A CPR_1060 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 110801704 Pathogen - hypothetical protein CPR_0023 1 None None None 110802461 Pathogen - hypothetical protein CPR_2081 1 None None None 110803945 Pathogen - hypothetical protein CPR_0470 3 None None None 110803513 Common - oligopeptide transporter, OPT family CPR_1276 41 COG1297 COG1297, Predicted membrane protein Function unknown 110803240 Common feoA ferrous iron repressor CPR_0971 4 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110803472 Common - Penicillin-binding Protein dimerisation domain family CPR_2107 191 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110802417 Pathogen - hypothetical protein CPR_1186 1 None None None 110803121 Common speE spermidine synthase CPR_0515 128 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 110801912 Common - PTS system, mannose/fructose/sorbose family, IID component CPR_0806 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 110803547 Common - HD domain protein CPR_0027 46 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 110802339 Common nrdD anaerobic ribonucleoside triphosphate reductase CPR_2516 110 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 110801884 Common - probable spore germination protein, putative CPR_0614 2 None None None 110803564 Common - rubrerythrin CPR_1331 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 110803931 Pathogen - hypothetical protein CPR_0375 1 None None None 110802486 Common - guanylate kinase-like protein CPR_2447 78 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 110802666 Common - hypothetical protein CPR_0961 4 None None None 110803017 Pathogen - hypothetical protein CPR_1079 1 None None None 110802142 Common - hypothetical protein CPR_2083 1 COG1714 COG1714, Predicted membrane protein/domain Function unknown 110801972 Pathogen - hypothetical protein CPR_1252 1 None None None 110803963 Common - transcriptional regulator, Fur family CPR_1230 197 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110803882 Common - hypothetical protein CPR_1926 1 None None None 110801619 Common clpB clpB protein CPR_1416 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 110802845 Common - probable phosphatase CPR_1102 100 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 110802469 Common cls cardiolipin synthetase CPR_0089 150 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110802009 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CPR_1753 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 110801928 Common - DNA-binding response regulator CPR_2497 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110801517 Common - thiamine pyrophosphokinase CPR_1706 54 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 110802686 Common infC translation initiation factor IF-3 CPR_1858 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 110802452 Common - DNA-binding response regulator CPR_1020 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110803247 Common - replication protein CPR_0633 5 None None None 110802503 Common - response regulatory protein (sensory transduction system) CPR_1758 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110802404 Common - amino acid ABC transporter, permease protein-like protein lin2352 CPR_0568 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110802945 Common - nuclease SbcCD, D subunit, putative CPR_0204 116 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 110803457 Common - magnesium and cobalt transport protein CorA, putative CPR_1075 114 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 110802236 Common - transmembrane protein Vexp1 CPR_2080 5 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110803938 Common - hypothetical protein CPR_2608 13 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803974 Common - teichoic acid linkage unit synthesis protein-like protein lin2663 CPR_1605 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 110801457 Common - phosphate import ATP-binding protein pstb CPR_0607 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 110801730 Pathogen - hypothetical protein CPR_1294 1 None None None 110803305 Common - spermidine/putrescine transport ATP-binding protein pota CPR_1935 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110802673 Common - acetyl-CoA acetyltransferase CPR_2170 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110803631 Common - nitroreductase family protein CPR_0173 92 COG0778 NfnB, Nitroreductase Energy production and conversion 110802405 Common - hypothetical protein CPR_1932 1 None None None 110803598 Common lonB ATP-dependent protease LonB CPR_1383 244 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110802728 Common rbfA ribosome-binding factor A CPR_1657 160 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 110801559 Common pilT twitching motility protein PilT CPR_1737 188 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 110802817 Common - hypothetical protein CPR_0793 73 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110802075 Common - dnaJ domain protein CPR_0236 7 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110801765 Common - hypothetical protein CPR_1618 1 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 110802258 Common sspC1 small, acid-soluble spore protein CPR_2035 10 None None None 110801739 Common selB selenocysteine-specific translation elongation factor CPR_2084 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 110802927 Common efp elongation factor P CPR_1803 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 110803425 Common - cell division protein FtsL, putative CPR_2484 4 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 110802296 Common selA selenocysteine synthase CPR_2085 74 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 110802283 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein CPR_1319 93 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110802325 Common - tRNA 2phosphotransferase CPR_0143 42 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 110802387 Pathogen - hypothetical protein CPR_0835 1 None None None 110803215 Common - HD domain protein CPR_2513 2 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110802805 Common - rhodanese-like domain protein CPR_2549 117 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110802276 Common - glycosyl hydrolase, family 20 CPR_1051 52 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 110802220 Pathogen - hypothetical protein CPR_1084 1 None None None 110802821 Common - ISCpe2, transposase orfB CPR_0126 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801867 Common - Ppx/GppA phosphatase family protein CPR_1634 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 110803897 Common - hypothetical protein CPR_0230 30 None None None 110802446 Common - phosphocarrier Protein (Hpr) CPR_1641 101 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 110801472 Common - IS1470, transposase CPR_0383 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110802959 Common hprK HPr kinase/phosphorylase CPR_1074 77 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 110802764 Common - pilus biogenesis protein, putative CPR_1811 145 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 110802693 Common - NlpC/P60 family CPR_0265 89 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 110801903 Common - ABC transporter (ATP binding protein)-like protein lin0829 CPR_2282 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110803847 Common - hypothetical protein CPR_2639 17 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 110803093 Common - hypothetical protein CPR_1580 2 None None None 110802125 Common - transcriptional regulatory protein, putative CPR_1606 9 COG4189 COG4189, Predicted transcriptional regulator Transcription 110803358 Common rpmF 50S ribosomal protein L32 CPR_1693 64 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 110802175 Common - permease CPR_2586 167 COG2252 COG2252, Permeases General function prediction only 110803309 Common - hypothetical protein CPR_2653 1 None None None 110803780 Common accA acetyl-CoA carboxylase, carboxyl transferase, alpha subunit CPR_1144 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 110802529 Common - permease, putative domain protein CPR_1981 6 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110803355 Common - MiaB-like tRNA modifying enzyme YliG CPR_1647 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110801499 Common - penicillin-binding protein 5* precursor CPR_1770 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110803784 Common dprA DNA protecting protein DprA CPR_1675 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 110802886 Common - cobalamin biosynthesis protein cobU, putative, truncation CPR_1111 2 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 110802110 Common kduI 5-keto-4-deoxyuronate isomerase CPR_0391 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 110801683 Common atpB F0F1 ATP synthase subunit A CPR_2168 161 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 110802146 Common rbsK ribokinase CPR_1603 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110802615 Common - Homocysteine S-methyltransferase, putative CPR_1406 162 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 110802360 Pathogen - hypothetical protein CPR_1355 1 None None None 110801490 Common - hypothetical protein CPR_0193 82 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 110802263 Common - Patatin-like phospholipase family CPR_1546 47 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 110801793 Common - pilus biogenesis protein, putative CPR_1812 212 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 110803441 Common - DAK2 domain protein CPR_1703 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 110801979 Common - CRISPR-associated protein Csx8, putative CPR_0919 4 None None None 110803026 Common - hydrolase, alpha/beta fold family CPR_0429 106 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110802860 Common dtd D-tyrosyl-tRNA deacylase CPR_1903 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 110803951 Common - hypothetical protein CPR_0622 4 None None None 110802712 Common - ISCpe3, transposase CPR_1044 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801677 Common scpA segregation and condensation protein A CPR_1774 145 COG1354 COG1354, Uncharacterized conserved protein Function unknown 110803835 Common prsA peptidylprolyl isomerase CPR_2492 121 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 110802620 Common - hypothetical protein CPR_0052 2 None None None 110802378 Common uvrB excinuclease ABC subunit B CPR_0295 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 110802506 Common - S4 domain protein CPR_2487 45 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 110803410 Common coaE dephospho-CoA kinase CPR_1961 187 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 110803169 Common - alcohol dehydrogenase, short-chain family CPR_2045 26 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 110802683 Common prmA ribosomal protein L11 methyltransferase CPR_2067 160 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 110801533 Pathogen - hypothetical protein CPR_0969 1 None None None 110803337 Pathogen - hypothetical protein CPR_0018 1 None None None 110802744 Common thiD phosphomethylpyrimidine kinase CPR_1338 222 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 110803039 Pathogen - hypothetical protein CPR_1968 1 None None None 110803834 Common - ABC transporter, ATP-binding protein CPR_0728 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110801828 Common - conserved hypothetical protein TIGR00149 CPR_0534 130 COG0432 COG0432, Uncharacterized conserved protein Function unknown 110801748 Common - histidine decarboxylase, pyruvoyl type CPR_0373 6 None None None 110803164 Common rimM 16S rRNA-processing protein CPR_1682 127 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 110802218 Common - hypothetical protein CPR_1033 6 None None None 110802033 Common - flavodoxin CPR_2033 24 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110801645 Common fusA elongation factor G CPR_2403 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110803260 Common ftsH ATP-dependent metalloprotease FtsH CPR_0565 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 110802244 Common dnaJ chaperone protein DnaJ CPR_2004 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110803421 Common - copper-translocating P-type ATPase CPR_0518 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110801681 Common - malolactic regulator, LysR family CPR_0142 153 COG0583 LysR, Transcriptional regulator Transcription 110802332 Common spoVB stage V sporulation protein B CPR_1619 52 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110802697 Common - L-asparaginase, type II CPR_1723 138 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 110802488 Common brnQ branched-chain amino acid transport system II carrier protein CPR_0388 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 110803432 Common - transcriptional regulator, AraC family, truncation CPR_1048 115 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110802023 Pathogen - putative lipoprotein CPR_1496 1 None None None 110802551 Common - DNA-binding protein CPR_1934 101 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 110802738 Common mgtE magnesium transporter CPR_1255 169 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 110801606 Common - amino acid ABC transporter CPR_0567 178 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110802136 Common spoIVA stage IV sporulation protein A CPR_1724 15 COG0536 Obg, Predicted GTPase General function prediction only 110803903 Common - chloride channel protein CPR_1400 152 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110803269 Common - putative dihydrouridine synthase CPR_2469 219 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110803163 Common - RNA methyltransferase, TrmA family CPR_0348 202 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 110802569 Pathogen - hypothetical protein CPR_1808 1 None None None 110802645 Common - Domain of unknown function DUF147 family CPR_2429 30 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 110803863 Common - ABC transporter, permease protein, putative CPR_0729 71 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 110802701 Common - lrgB-like family protein CPR_1948 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 110801741 Common - amino acid permease family protein CPR_1012 116 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110803050 Common - putative monogalactosyldiacylglycerol synthase CPR_2180 26 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110802725 Common - Sua5/YciO/YrdC/YwlC family protein CPR_2174 236 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 110802238 Common - hypothetical protein CPR_0775 7 None None None 110803727 Pathogen - hypothetical protein CPR_2009 1 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 110803106 Common dnaN DNA polymerase III subunit beta CPR_0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 110803059 Common cotJB spore coat peptide assembly protein CotJB CPR_0933 9 None None None 110802562 Common cobK cobalt-precorrin-6x reductase CPR_1233 47 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 110801712 Common argF ornithine carbamoyltransferase CPR_0158 235 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 110803722 Common - probable permease CPR_1751 111 COG0628 PerM, Predicted permease General function prediction only 110803030 Common - phosphorylase 2 CPR_2332 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 110803203 Common - hypothetical protein CPR_2002 2 None None None 110803043 Common spoVS stage V sporulation protein S CPR_1643 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 110802548 Common - hypothetical protein CPR_0871 5 None None None 110801624 Common - degV family protein CPR_0296 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110803235 Common - hypothetical protein CPR_1627 6 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 110802204 Common - uncharacterized conserved protein, YdjX/UPF0043 family CPR_1585 3 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110802092 Common yihY YihY family protein CPR_0272 143 COG1295 Rbn, Predicted membrane protein Function unknown 110803264 Common rpsJ 30S ribosomal protein S10 CPR_2400 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 110802627 Common hisS histidyl-tRNA synthetase CPR_1900 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110802483 Common - butyrate kinase CPR_2342 138 COG3426 COG3426, Butyrate kinase Energy production and conversion 110802114 Common rpsA 30S ribosomal protein S1 CPR_2117 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 110803689 Common rpe ribulose-phosphate 3-epimerase CPR_1707 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 110801921 Common - hypothetical protein CPR_1377 1 None None None 110802777 Common - AhpC/TSA family protein CPR_0251 221 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110803402 Common dapB dihydrodipicolinate reductase CPR_1873 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 110802635 Common - transcriptional regulator, DeoR family CPR_0708 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110802648 Common - conserved membrane protein, probable transporter, YPAA CPR_2135 22 COG3601 COG3601, Predicted membrane protein Function unknown 110802211 Common nth endonuclease III CPR_1318 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 110801632 Common - hypothetical protein CPR_0336 94 COG0391 COG0391, Uncharacterized conserved protein Function unknown 110802873 Pathogen - hypothetical protein CPR_2511 1 None None None 110803140 Common nusA transcription elongation factor NusA CPR_1661 227 COG0195 NusA, Transcription elongation factor Transcription 110803194 Common gpr germination protease CPR_2013 15 None None None 110802268 Common - hypothetical protein CPR_0147 3 None None None 110803808 Common - hypothetical protein CPR_2064 1 None None None 110803713 Common - PRC-barrel domain protein CPR_1752 1 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 110803822 Common - sulfatase family protein CPR_0575 57 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110801586 Common purD phosphoribosylamine--glycine ligase CPR_0676 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 110803312 Common - Resolvase, N terminal domain family CPR_0941 25 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 110803191 Common pcp pyrrolidone-carboxylate peptidase CPR_1413 51 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 110803119 Pathogen - hypothetical protein CPR_0062 1 None None None 110803620 Common - peptidase, S41 family CPR_1284 7 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110801811 Common - helicase/exonuclease CPR_0421 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110801461 Common - PhoH family protein CPR_1637 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 110802222 Pathogen - hypothetical protein CPR_0873 2 None None None 110803360 Common - ISCpe3, transposase CPR_0630 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801766 Common - aspartate kinase I CPR_1650 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 110803964 Pathogen - hypothetical protein CPR_2485 1 None None None 110802444 Common - phage infection protein, putative CPR_2594 30 COG1511 COG1511, Predicted membrane protein Function unknown 110801598 Common def polypeptide deformylase CPR_1604 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 110802654 Common folP dihydropteroate synthase CPR_1098 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 110801839 Common - potassium uptake protein, TrkH family CPR_1855 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110802595 Common - hypothetical protein CPR_1070 15 None None None 110803922 Pathogen - hypothetical protein CPR_2253 1 None None None 110801444 Common - sensory box histidine kinase CPR_1728 225 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110801664 Common - glycosyltransferase ycbB CPR_0571 188 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110802476 Common - hypothetical protein CPR_2517 14 None None None 110801706 Common hemA glutamyl-tRNA reductase CPR_1424 176 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 110803875 Common - drug resistance transporter, EmrB/QacA family CPR_1253 214 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110803283 Common - phosphate ABC transporter, permease protein CPR_0605 234 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110801963 Pathogen - hypothetical protein CPR_0875 1 None None None 110801505 Common aroE shikimate 5-dehydrogenase CPR_0693 222 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110801969 Common - transporter, major facilitator family CPR_2069 11 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110801572 Common cmk cytidylate kinase CPR_1151 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 110801727 Common - antibiotic ABC transporter, permease protein CPR_0819 45 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 110802889 Common - ISCpe4, transposase CPR_0148 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803348 Pathogen - hypothetical protein CPR_0765 1 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 110801844 Common - prophage ps3 protein 01, putative CPR_0353 28 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 110803291 Common - Binding-protein-dependent transport systems inner membrane component domain protein CPR_0906 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110802983 Common - polyA polymerase family protein CPR_0026 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 110803829 Pathogen - putative lipoprotein CPR_1543 1 None None None 110801954 Common - hypothetical protein CPR_1697 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 110803097 Common msrB methionine sulfoxide reductase B CPR_1577 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110802380 Common - hypothetical protein CPR_0285 1 None None None 110802538 Common pfkA 6-phosphofructokinase CPR_0341 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110801916 Pathogen - hypothetical protein CPR_0229 1 None None None 110803752 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CPR_1138 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110802523 Common - ribosome-associated GTPase CPR_1708 163 COG1162 COG1162, Predicted GTPases General function prediction only 110801520 Common moaA molybdenum cofactor biosynthesis protein A CPR_1760 208 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110801933 Common - dihydrouridine synthase family protein CPR_1273 197 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110802573 Common cotS spore coat protein CotS CPR_2192 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110803801 Common - aspartate aminotransferase CPR_1874 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110801851 Common acpP acyl carrier protein CPR_1691 98 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110801709 Common - cobalt ABC transporter, ATP-binding protein CPR_0185 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110803170 Common - sodium:glactoside symporter family protein CPR_0748 83 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 110801940 Common - hypothetical protein CPR_0065 45 COG4198 COG4198, Uncharacterized conserved protein Function unknown 110802541 Common - V-type ATP synthase subunit D CPR_1607 45 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 110803258 Common - transcription repressor smtb-like protein PAB0625 CPR_2290 193 COG0640 ArsR, Predicted transcriptional regulators Transcription 110803134 Common - glycosyltransferase CPR_2197 184 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110803316 Common - iron compound ABC transporter, ATP-binding protein, putative CPR_1117 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110801524 Common aga alpha-galactosidase CPR_0475 42 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 110803478 Common - MATE efflux family protein CPR_2514 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110802575 Common - ABC transporter, permease protein CPR_0541 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110802052 Common - ISCpe2, transposase orfB CPR_0505 58 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802662 Common - ISCpe2, transposase orfB CPR_1583 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803112 Common - cell division protein FtsQ CPR_1826 11 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 110803859 Common - hypothetical protein CPR_2592 11 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 110801771 Common - ISCpe2, transposase orfA CPR_0546 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802804 Common - sulfate permease, SulP family CPR_1459 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 110801989 Common - cellobiose phosphotransferase enzyme IIB component-like protein lmo2683 CPR_2199 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 110803996 Common yqfC sporulation protein YqfC CPR_1993 15 None None None 110803073 Common clpP ATP-dependent Clp protease proteolytic subunit CPR_1385 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110803311 Common - oxidoreductase, pyridine nucleotide-disulphide family CPR_2557 183 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110801787 Common - hypothetical protein CPR_1845 56 COG1683 COG1683, Uncharacterized conserved protein Function unknown 110801960 Common - choline/ethanolamine kinase family protein CPR_0594 29 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110803367 Common - hypothetical protein CPR_0425 1 None None None 110801568 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CPR_2616 226 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 110803748 Common - hypothetical protein CPR_1919 46 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 110802014 Common fhuB iron compound ABC transporter, permease protein CPR_0795 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110801778 Common ytxC putative sporulation protein YtxC CPR_1859 14 None None None 110802456 Common rpsO 30S ribosomal protein S15 CPR_1653 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 110802090 Common - polysaccharide deacetylase (nodulation protein NodB) CPR_1836 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110802140 Common - NUDIX domain protein CPR_0736 83 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 110802390 Pathogen - hypothetical protein CPR_1492 1 None None None 110801958 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase CPR_2461 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 110803088 Common - glycosyl transferase, group 1 family protein CPR_0588 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110802463 Common - TldD/PmbA family protein CPR_0326 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 110802016 Common pyrH uridylate kinase CPR_1670 241 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 110802068 Common - hypothetical protein CPR_2428 9 None None None 110803488 Common upp uracil phosphoribosyltransferase CPR_2172 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 110802735 Common - hypothetical protein CPR_1213 20 COG2389 COG2389, Uncharacterized metal-binding protein General function prediction only 110801596 Common - BadF/BadG/BcrA/BcrD ATPase family protein CPR_1861 53 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 110803605 Common lgt prolipoprotein diacylglyceryl transferase CPR_2523 118 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 110801639 Common - haloacid dehalogenase, IA family protein CPR_0260 182 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 110802337 Common dnaB replicative DNA helicase CPR_2648 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 110803483 Common - endonuclease/exonuclease/phosphatase family protein CPR_1127 26 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 110803702 Pathogen - hypothetical protein CPR_0859 1 None None None 110802792 Common - ISCpe7, transposase CPR_1313 53 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803500 Common metG methionyl-tRNA synthetase CPR_2532 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803988 Common - transcription regulator CPR_1302 59 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 110803680 Common - hypothetical protein CPR_1721 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 110802844 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase CPR_1787 218 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 110802375 Common infA translation initiation factor IF-1 CPR_2375 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 110803558 Pathogen - hypothetical protein CPR_0696 1 None None None 110803470 Common - tetratricopeptide repeat protein CPR_1887 22 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110802942 Common - cobalamin biosynthesis protein CbiG CPR_1235 83 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 110803949 Common - beta-1,4-N-acetyl-mannosaminyltransferase, putative CPR_0458 113 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 110803246 Common - transcriptional regulator, MarR family CPR_0962 90 COG1846 MarR, Transcriptional regulators Transcription 110803872 Common - spermidine/putrescine ABC transporter, permease protein (potC)-like protein CPR_1937 173 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110802894 Common - hypothetical protein CPR_2266 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 110803551 Common - cysteine desulfurase family protein CPR_2661 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110803947 Common mglC beta-methylgalactoside transporter inner membrane component CPR_1343 108 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 110802597 Common - cation transport ATPase yqgG CPR_0558 117 COG1285 SapB, Uncharacterized membrane protein Function unknown 110801553 Common - PTS system, sucrose-specific IIBC component CPR_1513 44 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110801983 Pathogen - hypothetical protein CPR_1535 1 None None None 110801886 Common - V-type ATP synthase subunit B CPR_1608 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 110802866 Common - hypothetical protein CPR_0114 3 None None None 110803545 Common - acetyltransferase, GNAT family CPR_1193 36 COG0456 RimI, Acetyltransferases General function prediction only 110802021 Common - alginate biosynthesis protein AlgI, putative CPR_1495 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 110803397 Common - hypothetical protein CPR_2096 6 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 110802106 Common - FliB domain protein CPR_0786 6 None None None 110801617 Pathogen - DNA repair protein rad50, putative CPR_0386 1 None None None 110803693 Common gyrB DNA gyrase subunit B CPR_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110802261 Common - membrane proteins-like protein lmo0908, putative CPR_0554 201 COG0628 PerM, Predicted permease General function prediction only 110803423 Common - probable amino acid permease PA1819, putative CPR_0079 192 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801876 Common - pentapeptide repeat family protein CPR_1017 1 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110803376 Common - copper homeostasis protein CutC, putative CPR_0248 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 110803893 Common - hypothetical protein CPR_0281 1 None None None 110802603 Common - probable flavoprotein, YhiN family CPR_2635 146 COG2081 COG2081, Predicted flavoproteins General function prediction only 110803455 Common - hypothetical protein CPR_2278 13 None None None 110801862 Common comB 2-phosphosulfolactate phosphatase CPR_2562 48 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 110803232 Common - hypothetical protein CPR_1131 1 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110801879 Common - malate oxidoreductase (NAD) (malic enzyme) CPR_1167 202 COG0281 SfcA, Malic enzyme Energy production and conversion 110802966 Common - aldehyde dehydrogenase CPR_2296 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110803044 Common - bioY family protein CPR_1515 110 COG1268 BioY, Uncharacterized conserved protein General function prediction only 110803389 Common arsC anaerobic sulfite reductase, subunit C CPR_1425 127 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110802836 Common radA DNA repair protein RadA CPR_2430 222 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 110803327 Pathogen - hypothetical protein CPR_0080 1 None None None 110803221 Pathogen - hypothetical protein CPR_2001 1 None None None 110803189 Common - NAD-dependent malic enzyme CPR_0140 202 COG0281 SfcA, Malic enzyme Energy production and conversion 110801780 Pathogen - hypothetical protein CPR_2596 3 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 110803760 Common - oxidoreductase, short chain dehydrogenase/reductase family CPR_2584 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110802974 Common - Mur ligase family protein CPR_1206 46 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110803577 Common - 5-keto-4-deoxyuronate isomerase CPR_0395 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 110803667 Common - cation efflux family protein CPR_0576 218 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110803029 Common - transposase, IS605 family CPR_0219 5 None None None 110802900 Pathogen - collagen triple helix repeat protein CPR_1027 1 None None None 110802711 Common - hypothetical protein CPR_0926 1 None None None 110802063 Pathogen - hypothetical protein CPR_1506 1 None None None 110803664 Common - ABC transporter, permease protein CPR_0478 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110802652 Pathogen - bacteriocin, putative CPR_0317 1 None None None 110802979 Common - cymH protein CPR_0789 166 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110802323 Common - HIT family protein CPR_1996 232 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 110802183 Common - hypothetical protein CPR_1498 1 None None None 110801515 Common ytvI sporulation integral membrane protein YtvI CPR_2662 11 COG0628 PerM, Predicted permease General function prediction only 110802789 Common - hypothetical protein CPR_1447 13 None None None 110802190 Common - xanthine permease CPR_0384 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110802425 Common - iron compound ABC transporter, permease protein CPR_0779 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110803496 Common - hypothetical protein CPR_1444 4 None None None 110802871 Pathogen - hypothetical protein CPR_0101 1 None None None 110801695 Common galE UDP-glucose 4-epimerase CPR_0468 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 110802313 Common arsC arsenate reductase ArsC CPR_0827 114 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110802434 Common - pullulanase CPR_0084 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110802048 Common holA DNA polymerase III subunit delta CPR_2015 42 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 110802278 Common - accessory gene regulator protein B, putative CPR_1532 5 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 110802253 Common sigG sporulation sigma factor SigG CPR_1732 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110802385 Common - mannose-1-phosphate guanylyltransferase CPR_2294 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 110801540 Common - DNA-binding response regulator CPR_1003 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110802691 Pathogen - hypothetical protein CPR_0900 3 None None None 110803593 Common purN phosphoribosylglycinamide formyltransferase CPR_0674 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 110802138 Common - CRISPR-associated protein Cas4 CPR_0914 36 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 110803578 Common - hypothetical protein CPR_1191 14 COG4720 COG4720, Predicted membrane protein Function unknown 110801464 Common - hypothetical protein CPR_0463 11 None None None 110801474 Common - dipeptidase PepV CPR_1231 173 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110803139 Pathogen - hypothetical protein CPR_0662 1 None None None 110803353 Common - hypothetical protein CPR_1397 14 None None None 110803213 Common - aminotransferase, class V CPR_1448 233 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110801736 Common ppdK pyruvate phosphate dikinase CPR_1983 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 110802953 Common - hypothetical protein CPR_2160 1 None None None 110801579 Common - sulfatase CPR_2207 69 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110803933 Common - hypothetical protein CPR_2293 1 None None None 110801450 Common - TrkA domain protein CPR_0508 6 None None None 110801550 Common - iron-sulfur cluster-binding protein CPR_0221 2 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110802614 Common - teichuronic acid biosynthesis glycosyl transferase, putative CPR_0256 51 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110802827 Common polA DNA polymerase I CPR_1962 219 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 110802127 Common - hypothetical protein CPR_0337 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 110802587 Common - Na+/H+ antiporter, putative CPR_1038 143 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110802131 Common - transcriptional regulator, AraC family CPR_0474 130 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110803774 Common - hypothetical protein CPR_0368 142 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110801570 Common - Signal peptidase I CPR_0427 168 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110802560 Common - Bacterial extracellular solute-binding protein, putative CPR_0603 175 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 110801905 Common - DNA-binding response regulator CPR_0226 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110801855 Common lepA GTP-binding protein LepA CPR_2010 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 110802727 Common sigH RNA polymerase factor sigma-70 CPR_2418 37 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110803057 Common - CRISPR-associated protein Cas1 CPR_0915 32 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 110803380 Common - flavodoxin CPR_0611 27 COG0716 FldA, Flavodoxins Energy production and conversion 110803511 Pathogen - hypothetical protein CPR_0289 1 None None None 110803417 Common - hypothetical protein CPR_2292 3 None None None 110803466 Common spoIVB stage IV sporulation protein B CPR_1782 18 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110803356 Common - Amino acid transport ATP-binding protein CPR_1326 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110801539 Common - permease CPR_0510 79 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 110802601 Pathogen - hypothetical protein CPR_0808 1 None None None 110803659 Common cysE serine O-acetyltransferase CPR_1321 214 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 110802415 Common - cob(I)alamin adenosyltransferase, putative CPR_1875 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 110802376 Common - uncharacterized ABC transporter, ATPase component CPR_0495 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110803845 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase CPR_1725 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110802061 Common - hypothetical protein CPR_1626 25 COG2155 COG2155, Uncharacterized conserved protein Function unknown 110802750 Common - molybdopterin-guanine dinucleotide biosynthesis protein-like protein CPR_1762 68 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 110803394 Common - ISCpe5, transposase CPR_0684 1 None None None 110801802 Common - hypothetical protein CPR_1548 16 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 110802820 Common rpmA 50S ribosomal protein L27 CPR_2095 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 110803611 Common - hypothetical protein CPR_2244 1 None None None 110803782 Common - amino acid antiporter (acid resistance)-like protein lin2462 CPR_1297 54 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110802188 Common purB adenylosuccinate lyase CPR_1640 184 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 110802084 Common - small, acid-soluble spore protein CPR_1411 13 None None None 110803603 Common - MutT/nudix family protein, putative CPR_0782 27 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110801480 Pathogen - hypothetical protein CPR_1563 1 None None None 110801612 Pathogen - hypothetical protein CPR_2011 1 None None None 110802996 Common - pullulanase precursor CPR_1522 155 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 110801970 Common - hypothetical protein CPR_1720 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 110801583 Common mgsA methylglyoxal synthase CPR_1077 87 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 110803019 Common - hypothetical protein CPR_2571 1 None None None 110803589 Common - CRISPR-associated protein Cas1 CPR_0916 79 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 110803857 Pathogen - hypothetical protein CPR_1290 1 None None None 110802307 Common alaS alanyl-tRNA synthetase CPR_1750 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803571 Common plsX fatty acid/phospholipid synthesis protein CPR_1692 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 110802402 Common - FHA domain protein CPR_0330 67 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 110801804 Common pncB nicotinate phosphoribosyltransferase CPR_1227 107 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 110803868 Common - putative csfB protein CPR_2449 1 None None None 110802310 Common - hypothetical protein CPR_0727 19 COG1309 AcrR, Transcriptional regulator Transcription 110803792 Common - transcriptional regulator, LysR family CPR_1454 193 COG0583 LysR, Transcriptional regulator Transcription 110803983 Common - membrane spanning protein CPR_1562 24 COG3610 COG3610, Uncharacterized conserved protein Function unknown 110803518 Pathogen - hypothetical protein CPR_0385 1 None None None 110802501 Common prkA serine protein kinase CPR_1334 72 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 110802746 Common - sensory box/GGDEF domain/HD domain protein CPR_0996 189 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 110803529 Common tsf elongation factor Ts CPR_1671 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 110803976 Common - FemAB family protein CPR_2059 24 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 110802520 Common - putative RNA polymerase sigma factor CPR_0466 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110801634 Common - glycosyl transferase, group 1 family protein CPR_0586 180 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110802002 Pathogen - hypothetical protein CPR_0731 1 None None None 110802164 Common - hypothetical protein CPR_0932 1 None None None 110803127 Common rpmI 50S ribosomal protein L35 CPR_1857 192 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 110802351 Common pdp pyrimidine-nucleoside phosphorylase CPR_1776 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 110802298 Common thrS threonyl-tRNA synthetase CPR_2317 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803778 Pathogen - hypothetical protein CPR_1101 1 None None None 110802499 Common accD acetyl-CoA carboxylase, carboxyl transferase, beta subunit CPR_1143 220 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 110801798 Common - hypothetical protein CPR_0563 5 None None None 110802925 Common - glycolate oxidase subunit-like protein ysfC CPR_0305 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110802229 Common - ABC transporter, permease protein, FecCD family CPR_1116 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110802077 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CPR_1152 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 110801763 Common selD selenide, water dikinase, selenocysteine-containing CPR_2086 137 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 110803340 Pathogen - putative lipoprotein CPR_1594 1 None None None 110801926 Pathogen - hypothetical protein CPR_0511 1 None None None 110803654 Common - repeat organellar protein, putative CPR_1850 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110801996 Common - hypothetical protein CPR_1268 11 None None None 110802887 Common - surface protein pspA precursor CPR_0597 8 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110803157 Common rpsB 30S ribosomal protein S2 CPR_1672 231 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 110801746 Common - amidohydrolase, putative CPR_1951 71 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 110803346 Common - transport protein-like protein lmo0826 CPR_2362 121 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 110802058 Common - acylphosphatase CPR_1940 71 COG1254 AcyP, Acylphosphatases Energy production and conversion 110802872 Common - hypothetical protein CPR_1219 16 None None None 110801987 Common - hypothetical protein CPR_0574 17 COG5542 COG5542, Predicted integral membrane protein Function unknown 110803550 Common gmk guanylate kinase CPR_1719 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 110803941 Common tdk thymidine kinase CPR_2178 96 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 110802941 Common - PTS system, mannose/fructose/sorbose family, IIC component CPR_0805 30 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 110802660 Common asp alkaline shock protein CPR_1793 39 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 110802195 Common cobJ precorrin-3B C17-methyltransferase CPR_1234 187 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 110802040 Pathogen - hypothetical protein CPR_0262 1 None None None 110803993 Common - secreted protein CPR_1960 165 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110803196 Common - ISCpe2, transposase orfB CPR_0679 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801930 Common - hypothetical protein CPR_1104 11 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110802004 Common - [Fe] hydrogenase CPR_2579 31 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110803679 Common - cell wall binding repeat/mannosyl-glycoprotein endo-beta-N-acetylglucosamidase CPR_0592 10 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110803021 Common - acetobutylicum phosphotransbutyrylase CPR_0088 18 COG5652 COG5652, Predicted integral membrane protein Function unknown 110803075 Common - RNA methyltransferase, TrmH family, group 3 CPR_2420 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110802930 Common - amino acid antiporter (acid resistance)-like protein lin2462 CPR_2031 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110802091 Common - Bacterial transferase hexapeptide, putative CPR_0457 176 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 110802554 Common - transcriptional regulator, RpiR family CPR_0179 128 COG1737 RpiR, Transcriptional regulators Transcription 110803854 Common asrB anaerobic sulfite reductase subunit B CPR_1426 147 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110803110 Common - transcriptional regulator, PadR family CPR_2060 25 COG1695 COG1695, Predicted transcriptional regulators Transcription 110801942 Common - sporulation protein, putative CPR_1778 12 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 110802577 Common - hypothetical protein CPR_0719 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110803076 Common - YeeE/YedE family protein CPR_0716 59 None None None 110802653 Common - hypothetical protein CPR_1772 17 COG3874 COG3874, Uncharacterized conserved protein Function unknown 110801502 Common - transcriptional regulator, PadR family CPR_1145 2 COG1695 COG1695, Predicted transcriptional regulators Transcription 110802117 Common tyrS tyrosyl-tRNA synthetase CPR_0619 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803994 Common nrdG anaerobic ribonucleoside-triphosphate reductase activating protein CPR_2512 75 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110803256 Common glnS glutaminyl-tRNA synthetase CPR_0612 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110802710 Pathogen - hypothetical protein CPR_0942 1 None None None 110803806 Common - amino acid permease family protein CPR_0717 53 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801830 Common - Cysteine-rich domain family CPR_0544 107 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 110801603 Common - hydrolase, alpha/beta fold family CPR_1956 75 COG2267 PldB, Lysophospholipase Lipid metabolism 110801442 Pathogen - hypothetical protein CPR_1380 1 None None None 110803819 Common - hypothetical protein CPR_1073 8 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 110803622 Common nadC nicotinate-nucleotide pyrophosphorylase CPR_0378 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 110803028 Common - calcium-translocating P-type ATPase, PMCA-type CPR_0311 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110803523 Common infB translation initiation factor IF-2 CPR_1658 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 110802757 Common fhuC Ferrichrome transport ATP-binding protein fhuC CPR_0797 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110801481 Common - ISCpe5, transposase CPR_0686 10 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803915 Common ddl D-alanine--D-alanine ligase CPR_1312 217 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 110803961 Common hpt hypoxanthine phosphoribosyltransferase CPR_2473 154 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 110801536 Common udk uridine kinase CPR_1740 77 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 110803314 Common - hypothetical protein CPR_1271 4 None None None 110803721 Common purF amidophosphoribosyltransferase CPR_0672 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 110802098 Common - hypothetical protein CPR_1556 13 COG4720 COG4720, Predicted membrane protein Function unknown 110803812 Common - transketolase CPR_0287 223 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 110802630 Common - ISCpe2, transposase orfA CPR_0678 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802525 Common - acetyltransferase, GNAT family CPR_0704 11 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 110803742 Common rpsD 30S ribosomal protein S4 CPR_2354 241 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 110802441 Common - transcriptional regulator, Crp/Fnr family CPR_1428 94 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110801543 Common - sensor histidine kinase CPR_1954 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110803007 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase CPR_1545 97 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 110801618 Common - cell cycle protein, FtsW/RodA/SpoVE family CPR_0331 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110803828 Common - IS1470, transposase CPR_1578 8 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110802967 Common - hypothetical protein CPR_0110 12 COG4086 COG4086, Predicted secreted protein Function unknown 110802224 Common - hypothetical protein CPR_1704 35 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 110802216 Common addB ATP-dependent nuclease subunit B CPR_0024 34 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 110801959 Common argR arginine repressor CPR_1784 71 COG1438 ArgR, Arginine repressor Transcription 110803193 Common - V-type ATPase, E subunit CPR_1612 18 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 110802160 Common - metallo-beta-lactamase family protein CPR_2615 72 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 110803750 Common - DNA topoisomerase CPR_1950 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110803925 Common pyrD dihydroorotate dehydrogenase 1B CPR_1197 233 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 110803117 Common - subtilisin-like protease (two fused domains) CPR_2071 11 None None None 110802592 Common cspB protease CspB CPR_2567 61 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110802637 Common rbsC ribose transport system permease protein rbsC CPR_1600 107 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110803318 Common - phage infection protein, putative CPR_2593 47 COG1511 COG1511, Predicted membrane protein Function unknown 110803754 Common - alcohol dehydrogenase 2 CPR_0442 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110802880 Common - dnaK family protein CPR_0238 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 110801894 Common ksgA dimethyladenosine transferase CPR_2526 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 110803641 Common - transcriptional regulator, RpiR family CPR_2604 78 COG1737 RpiR, Transcriptional regulators Transcription 110802879 Common - putative thiosulfate sulfurtransferase CPR_1124 114 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110802972 Common - transcriptional regulator, LysR family CPR_0714 189 COG0583 LysR, Transcriptional regulator Transcription 110802747 Common - hypothetical protein CPR_1589 1 None None None 110802960 Common - ISCpe5, transposase CPR_0759 7 None None None 110803279 Common - ABC transporter (permease proteins)-like protein lmo1390 CPR_1550 133 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 110803274 Common - Initiator RepB protein family CPR_0315 32 COG5527 COG5527, Protein involved in initiation of plasmid replication DNA replication, recombination, and repair 110803085 Common - spore germination protein, GerABKA family CPR_0615 15 None None None 110801910 Common ssb single-strand binding protein CPR_2655 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110802811 Common sdhA L-serine dehydratase, iron-sulfur-dependent, alpha subunit CPR_1058 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110802783 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase CPR_1829 214 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 110803378 Common deoD purine nucleoside phosphorylase CPR_1391 101 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 110803172 Common - hypothetical protein CPR_1466 47 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110801475 Common - Bacterial extracellular solute-binding proteins, family 3 family CPR_0931 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110803332 Common hemB delta-aminolevulinic acid dehydratase CPR_1420 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 110802368 Common - ferredoxin (fdxA) CPR_2442 195 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110802994 Common - cell wall binding repeat/zinc carboxypeptidase family protein CPR_0591 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110802202 Common thiM hydroxyethylthiazole kinase CPR_1337 76 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 110801810 Common - mannosyl-glycoprotein endo-beta-N-acetylglucosamidase domain protein CPR_1245 23 COG4193 LytD, Beta- N-acetylglucosaminidase Carbohydrate transport and metabolism 110801693 Common - bacteriocin ABC transporter, ATP-binding/permease protein, putative CPR_1082 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 110802504 Common - hypothetical protein CPR_2195 1 None None None 110801971 Common brnQ branched-chain amino acid transport system II carrier protein CPR_0599 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 110801823 Common fba fructose-1,6-bisphosphate aldolase, class II CPR_1350 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 110802511 Common - hydroxylamine reductase CPR_0974 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 110802367 Common - acetyltransferase, GNAT family CPR_0069 125 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110803266 Common - ISCpe2, transposase orfB CPR_0168 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803731 Common - hypothetical protein CPR_0747 14 None None None 110801724 Common - hypothetical protein CPR_0985 9 None None None 110801626 Common citX Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase CPR_1166 25 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 110803454 Common - hypothetical protein CPR_0446 3 COG1289 COG1289, Predicted membrane protein Function unknown 110802518 Common - hypothetical protein CPR_0613 11 None None None 110803298 Common - serine protease CPR_2200 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110803047 Common - hypothetical protein CPR_0115 8 COG4640 COG4640, Predicted membrane protein Function unknown 110801449 Pathogen - hypothetical protein CPR_0380 1 None None None 110801819 Common - sugar kinase, putative CPR_2605 123 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110802625 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CPR_1893 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110802986 Common - hypothetical protein CPR_2574 1 None None None 110803953 Common - putative manganese-dependent inorganic pyrophosphatase CPR_2027 56 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 110802329 Common phoU phosphate transport system regulatory protein PhoU CPR_0608 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110803773 Common dhaT 1,3-propanediol dehydrogenase CPR_1011 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110803202 Common - ISCpe7, transposase CPR_0681 52 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803460 Common - ISCpe7, transposase CPR_0930 23 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801633 Common - Ser/Thr protein phosphatase family protein CPR_2238 68 COG0622 COG0622, Predicted phosphoesterase General function prediction only 110802031 Common oxaA putative inner membrane protein translocase component YidC CPR_2671 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 110801837 Common entA probable enterotoxin CPR_1266 10 None None None 110803616 Common - ISCpe4, transposase CPR_0278 71 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802149 Common - DedA family protein CPR_0447 154 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110802330 Common - hypothetical protein CPR_1013 4 COG2717 COG2717, Predicted membrane protein Function unknown 110803053 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CPR_0667 107 COG0756 Dut, dUTPase Nucleotide transport and metabolism 110803777 Common - uncharacterized ABC transporter, ATPase component CPR_0494 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110803904 Common - hypothetical protein CPR_1327 1 None None None 110801919 Common - transcriptional regulator, CarD family CPR_0246 2 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 110803182 Common - sensory box histidine kinase/response regulator CPR_1055 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110802373 Common - teichuronic acid biosynthesis glycosyl transferase, putative CPR_0257 52 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110801565 Common - hypothetical protein CPR_0450 32 COG1289 COG1289, Predicted membrane protein Function unknown 110802719 Common mreB rod shape-determining protein MreB CPR_2110 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 110803405 Common nagB glucosamine-6-phosphate deaminase CPR_2431 82 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 110802999 Common - hypothetical protein CPR_2534 6 COG4129 COG4129, Predicted membrane protein Function unknown 110803300 Common - aminotransferase, class V CPR_0839 155 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 110802931 Common - ISCpe2, transposase orfB CPR_0626 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803982 Common priA primosome assembly protein PriA CPR_1716 208 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 110802542 Common rplO 50S ribosomal protein L15 CPR_2380 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 110803534 Common - amidohydrolase-like protein CPR_2450 57 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110803434 Pathogen - hypothetical protein CPR_1509 1 None None None 110803178 Common - DNA-binding response regulator, AraC family CPR_0539 209 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110803013 Common - Cof-like hydrolase, HAD-superfamily, subfamily IIB CPR_0803 99 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110802389 Common truA tRNA pseudouridine synthase A CPR_2365 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 110801700 Common - glycosyltransferase CPR_0584 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110802326 Common hbd 3-hydroxybutyryl-CoA dehydrogenase CPR_2283 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110803588 Common - ISCpe2, transposase orfA CPR_1030 8 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801463 Common - hypothetical protein CPR_0923 5 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 110802868 Common lon ATP-dependent protease La CPR_1382 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 110801900 Common - acetyltransferase, GNAT family CPR_0430 2 COG0456 RimI, Acetyltransferases General function prediction only 110802026 Common - Na+/H+ antiporter family family CPR_2303 59 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 110803569 Common - carboxypeptidase-like protein CPR_1371 40 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110803033 Common - subtilase family protein CPR_2620 55 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110802243 Common - putative immunity protein CPR_0232 2 None None None 110801967 Common - sortase family protein CPR_2301 35 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110803124 Common rpoN RNA polymerase factor sigma-54 CPR_1303 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 110802774 Common cas3 CRISPR-associated helicase Cas3 domain protein CPR_0922 104 COG1203 COG1203, Predicted helicases General function prediction only 110802357 Common - C4-dicarboxylate anaerobic carrier family protein CPR_1054 38 COG1288 COG1288, Predicted membrane protein Function unknown 110802722 Common - hypothetical protein CPR_1109 1 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 110802643 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III CPR_1136 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 110801496 Common - fructose specific permease CPR_0550 145 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 110803087 Common - sulfatase family protein CPR_0570 69 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110802605 Common trmD tRNA (guanine-N(1)-)-methyltransferase CPR_1681 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 110801635 Pathogen - hypothetical protein CPR_0103 1 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 110803573 Common narA nitrate reductase, catalytic subunit CPR_1767 187 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110801494 Common - sodium/alanine symporter family protein CPR_1931 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 110803562 Common - hypothetical protein CPR_1869 52 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 110801946 Common - UDP-N-acetylglucosamine 2-epimerase CPR_2171 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 110802465 Common - pyrophosphatase PpaX CPR_1944 211 COG0546 Gph, Predicted phosphatases General function prediction only 110803635 Common - hypothetical protein CPR_0343 3 None None None 110803790 Common - transcriptional regulator, LacI family CPR_1598 129 COG1609 PurR, Transcriptional regulators Transcription 110801977 Common - L-lactate permease CPR_0302 104 COG1620 LldP, L-lactate permease Energy production and conversion 110801687 Common - DNA replication protein DnaD, putative CPR_2622 8 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 110803885 Pathogen - prepilin peptidase-dependent CPR_2264 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 110803798 Common - amidohydrolase family protein CPR_1225 174 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110801917 Common arcD arginine/ornithine antiporter CPR_0159 161 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801465 Common fabZ beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ CPR_1141 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 110803970 Common - Voltage gated chloride channel family CPR_0556 164 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110801670 Common - beta-glucosidase a CPR_2295 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 110802400 Pathogen - prepilin peptidase-dependent CPR_1810 1 None None None 110802198 Common - hypothetical protein CPR_1910 5 None None None 110803452 Pathogen - hypothetical protein CPR_0647 1 None None None 110802076 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type CPR_2570 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110802801 Common brnQ branched-chain amino acid transport system II carrier protein CPR_0049 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 110802585 Common - hypothetical protein CPR_1494 11 None None None 110801643 Common - CBS domain protein CPR_2131 31 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110802923 Common - degV family protein CPR_2518 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110803681 Common - uncharacterized ABC transporter, ATPase component CPR_0364 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110803852 Common - lysine-specific permease CPR_1182 173 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 110801511 Common - methyltransferase, putative CPR_1816 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 110801580 Common - conserved hypothetical protein TIGR00257 CPR_1923 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 110801735 Common - hypothetical protein CPR_2113 1 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 110801750 Common - cysteine-rich domain protein CPR_2072 56 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 110802303 Common minD septum site-determining protein MinD CPR_2105 147 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 110802272 Common - Leucine Rich Repeat domain protein CPR_1278 14 None None None 110802497 Common - aminopeptidase CPR_1965 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110801555 Common - hypothetical protein CPR_2298 45 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 110801513 Common soj sporulation initiation inhibitor protein soj CPR_2666 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110802279 Common - hypothetical protein CPR_1090 7 None None None 110802178 Common - oligopeptide ABC transporter, ATPase component CPR_2254 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 110803236 Common - hypothetical protein CPR_2268 2 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 110803967 Common - hypothetical protein CPR_2589 1 None None None 110803516 Common - choline/ethanolamine kinase family protein CPR_1107 17 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110802315 Common - tetratricopeptide repeat protein CPR_1129 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 110803978 Common - beta-galactosidase CPR_0815 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 110802412 Pathogen - hypothetical protein CPR_1502 1 None None None 110802133 Common - GTPase EngB CPR_1381 201 COG0218 COG0218, Predicted GTPase General function prediction only 110803874 Common rho transcription termination factor Rho CPR_2181 205 COG1158 Rho, Transcription termination factor Transcription 110803331 Common - hypothetical protein CPR_0241 1 None None None 110801722 Common - FliB family protein CPR_0878 7 None None None 110803409 Common atpH F0F1 ATP synthase subunit delta CPR_2165 193 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 110803351 Common - metal (zinc) transport protein (ABC transporter, permease protein) zurM CPR_1443 193 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 110802612 Common - TspO/MBR family protein CPR_1952 64 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 110802677 Common - ISCpe7, transposase CPR_1189 6 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803509 Pathogen - hypothetical protein CPR_1221 1 None None None 110801655 Common - AAA domain family protein CPR_0617 28 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 110802619 Common pepD aminoacyl-histidine dipeptidase CPR_2216 64 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110802800 Common - hypothetical protein CPR_2451 1 None None None 110803715 Common - pyridoxamine kinase CPR_2304 65 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 110802882 Common - hypothetical protein CPR_0951 2 None None None 110803763 Common - metallo-beta-lactamase family protein CPR_1480 123 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 110801907 Common ileS isoleucyl-tRNA synthetase CPR_2550 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110802917 Common - vanW-like family protein CPR_1310 39 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 110803152 Common - glutaminase CPR_0557 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 110802768 Common - glutamine transport protein glnQ CPR_0569 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110802752 Common mbl mbl protein CPR_2155 191 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 110802742 Common - phosphodiesterase/nucleotide pyrophosphatase family protein CPR_1367 39 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 110802940 Common - hypothetical protein CPR_0910 1 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 110801832 Common - beta-lactamase, putative CPR_1202 50 COG2367 PenP, Beta-lactamase class A Defense mechanisms 110803866 Common - hypothetical protein CPR_2664 13 None None None 110803129 Pathogen - hypothetical protein CPR_2169 1 None None None 110802232 Common - stage III sporulation protein SpoAB CPR_1800 14 None None None 110802670 Common - nucleoside hydrolase, IUNH family CPR_1971 86 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 110803211 Common - hypothetical protein CPR_1624 1 None None None 110801881 Common - von Willebrand factor type A domain protein CPR_2263 1 None None None 110802171 Common nadB L-aspartate oxidase CPR_0377 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 110803674 Common - DNA polymerase III, subunit alpha (dnaE)-like protein CPR_0339 217 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 110801615 Common - hypothetical protein CPR_1749 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 110802830 Common - uncharacterized conserved protein of YjeB/RRF2 family CPR_1756 179 COG1959 COG1959, Predicted transcriptional regulator Transcription 110801809 Common spoIIAA anti-sigma F factor antagonist CPR_2022 69 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 110802682 Common - hypothetical protein CPR_0504 2 None None None 110802443 Pathogen - hypothetical protein CPR_1154 1 None None None 110802928 Common dGK2 deoxynucleoside kinase family protein CPR_0070 40 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 110803241 Common - hypothetical protein CPR_0924 2 None None None 110802814 Common - ArsC family protein CPR_2357 83 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 110803419 Common pepA leucyl aminopeptidase CPR_2510 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 110803479 Pathogen - hypothetical protein CPR_1581 1 None None None 110801782 Common - amino acid permease family protein CPR_2046 58 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801874 Common - hypothetical protein CPR_2612 21 None None None 110802891 Common - ISCpe2, transposase orfB CPR_1049 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803023 Common - GIY-YIG domain protein CPR_1431 88 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 110802897 Common - hypothetical protein CPR_1469 4 None None None 110802042 Common rimI ribosomal-protein-alanine acetyltransferase CPR_2134 198 COG0456 RimI, Acetyltransferases General function prediction only 110802763 Common addA recombination helicase AddA CPR_0025 229 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 110803320 Common - oligo-1,6-glucosidase, truncation CPR_0526 9 None None None 110802155 Common tdcB threonine dehydratase, catabolic CPR_1181 221 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110801860 Common - glyoxalase I (glyoxalase family) CPR_0444 60 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110802492 Pathogen - hypothetical protein CPR_1804 1 None None None 110802708 Common - transcriptional regulator, TetR family CPR_0034 156 COG1309 AcrR, Transcriptional regulator Transcription 110802955 Common - ABC tranporter, permease protein CPR_0477 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110801573 Common uvsE putative UV damage endonuclease CPR_2043 27 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 110803096 Common - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, putative CPR_1876 142 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 110802193 Common - uncharacterized conserved protein, YABE CPR_1243 75 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 110802961 Common - sigma-54 dependent transcriptional regulator CPR_2075 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 110802426 Pathogen - hypothetical protein CPR_0138 1 None None None 110803497 Common - nucleoside diphosphate kinase CPR_1939 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 110803485 Common - hypothetical protein CPR_1069 32 COG5483 COG5483, Uncharacterized conserved protein Function unknown 110802162 Common - sensor histidine kinase CPR_2057 108 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 110802473 Common - two component regulator three Y motif protein CPR_2250 2 None None None 110802287 Common - Bacterial extracellular solute-binding proteins, family 5 superfamily CPR_2258 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110802937 Common fabD malonyl CoA-acyl carrier protein transacylase CPR_1137 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 110803224 Common asnA asparagine synthetase AsnA CPR_1945 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 110802185 Common glpK glycerol kinase CPR_2559 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 110801451 Common rpsR 30S ribosomal protein S18 CPR_2654 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 110802169 Common - ISCpe5, transposase CPR_0485 39 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802280 Common - hypothetical protein CPR_0713 53 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 110803844 Common glgB glycogen branching enzyme CPR_1559 154 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 110802260 Common - C4-dicarboxylate transporter/malic acid transport protein family CPR_0123 32 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 110801990 Pathogen - hypothetical protein CPR_0953 1 None None None 110802122 Common - hypothetical protein CPR_1282 13 COG1289 COG1289, Predicted membrane protein Function unknown 110801999 Common - hypothetical protein CPR_2190 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 110803767 Common mleP malate permease CPR_0141 33 COG0679 COG0679, Predicted permeases General function prediction only 110803789 Common ptsI phosphoenolpyruvate-protein phosphotransferase CPR_2352 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 110803412 Common - MiaB-like tRNA modifying enzyme CPR_1997 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110803927 Common - hypothetical protein CPR_0150 2 None None None 110802696 Pathogen - hypothetical protein CPR_0015 1 None None None 110803542 Pathogen lcnA bacteriocin lactococcin A CPR_1081 1 None None None 110803594 Common panE 2-dehydropantoate 2-reductase CPR_0771 129 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 110803448 Common - ABC transporter, substrate-binding protein CPR_2125 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 110802795 Common dapA dihydrodipicolinate synthase CPR_1872 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110803428 Common - ISCpe2, transposase orfA CPR_0625 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802432 Common - hypothetical protein CPR_0443 6 COG5561 COG5561, Predicted metal-binding protein Function unknown 110802066 Common - spore coat protein, putative CPR_2194 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110802594 Common - 3-methyladenine DNA glycosylase CPR_2580 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 110803695 Pathogen - hypothetical protein CPR_0359 2 None None None 110802352 Common - magnesium and cobalt transporter CPR_2452 127 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 110803646 Common - ISCpe7, transposase CPR_1473 46 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803382 Common - ABC1 domain protein CPR_2537 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 110802105 Common - hypothetical protein CPR_1440 2 None None None 110803010 Common - hypothetical protein CPR_2610 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 110803708 Common - Glycosyl hydrolase family 20, catalytic domain family CPR_0959 22 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 110801848 Common - degV family protein CPR_1307 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110803061 Common - phosphocarrier HPr/sensory box protein/sigma-54 dependent transcriptional regulator CPR_2353 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 110801888 Common - hypothetical protein CPR_2360 81 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110802305 Common dhaC glycerol dehydratase, beta subunit CPR_1005 13 None None None 110801800 Common - helicase, SNF2/RAD54 family CPR_1597 153 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 110801980 Common - stage III sporulation protein AH CPR_1794 3 None None None 110803187 Common - Glycosyl hydrolase family 85 family CPR_0280 13 COG4724 COG4724, Endo-beta-N-acetylglucosaminidase D Carbohydrate transport and metabolism 110803329 Common - small, acid-soluble spore protein, alpha/beta family CPR_1870 8 None None None 110802096 Common - cell cycle protein, FtsW/RodA/SpoVE family CPR_2103 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110803244 Common - Mg chelatase-like protein CPR_1676 202 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 110803555 Common - zinc-transporting atpase CPR_2289 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110802082 Common nrdF ribonucleotide-diphosphate reductase subunit beta CPR_2355 160 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 110802896 Common - probable peptidoglycan bound protein (LPXTG motif) lin2282, putative CPR_0144 13 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110801835 Common - hypothetical protein CPR_2611 4 None None None 110803697 Common - ATPase component of ABC transporter, with duplicated ATPase domains CPR_2553 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110802877 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase CPR_1329 148 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110801984 Common - hypothetical protein CPR_2344 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 110801483 Common - IS1470, transposase CPR_0358 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110803648 Pathogen - hypothetical protein CPR_1802 1 None None None 110802167 Common - ISCpe2, transposase orfB CPR_0547 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801440 Common - hypothetical protein CPR_1256 50 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110801601 Common - hypothetical protein CPR_0880 11 None None None 110802766 Pathogen - hypothetical protein CPR_2102 1 None None None 110802759 Common - hypothetical protein CPR_1275 6 None None None 110801873 Common - glycogen phosphorylase CPR_0083 148 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 110803001 Common yyaC putative sporulation protein YyaC CPR_2663 14 None None None 110803624 Common - lactococcin g processing and transport ATP-binding protein CPR_0319 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 110803384 Common - ISCpe6, transposase orfA CPR_0823 5 None None None 110801468 Common - thermophilic metalloprotease family protein CPR_0855 64 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110803744 Common thyX FAD-dependent thymidylate synthase CPR_2421 80 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 110802513 Common - hypothetical protein CPR_0998 2 None None None 110802430 Common - putative carbohydrate diacid regulator CPR_0844 47 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 110803008 Common ftsZ cell division protein FtsZ CPR_1735 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 110803287 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CPR_1108 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 110803651 Pathogen - hypothetical protein CPR_0896 1 None None None 110802992 Pathogen - hypothetical protein CPR_1863 1 None None None 110801544 Common - flavin reductase, putative CPR_1399 91 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110802590 Common - hypothetical protein CPR_2556 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 110801620 Common - DedA family protein CPR_0994 152 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110803826 Common - subtilase family protein CPR_2070 11 None None None 110802772 Common - hypothetical protein CPR_1185 17 COG2364 COG2364, Predicted membrane protein Function unknown 110801509 Common - Transcriptional regulator CPR_2503 131 COG1609 PurR, Transcriptional regulators Transcription 110801577 Pathogen - lipoprotein, putative CPR_1531 1 None None None 110803643 Common - conserved hypothetical protein TIGR00266 CPR_0312 76 COG2013 COG2013, Uncharacterized conserved protein Function unknown 110803907 Common - ISCpe7, transposase CPR_0784 53 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803705 Common rplI 50S ribosomal protein L9 CPR_2650 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 110802533 Common hisK histidinol-phosphatase CPR_1128 34 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110803756 Common glyS glycyl-tRNA synthetase CPR_2465 87 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 110801702 Common - hypothetical protein CPR_1052 2 COG4127 COG4127, Uncharacterized conserved protein Function unknown 110803968 Common - NADPH-dependent FMN reductase CPR_0869 42 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 110801500 Pathogen - hypothetical protein CPR_0901 1 None None None 110801660 Common - lipoprotein, putative CPR_1813 1 None None None 110801649 Common pyrR pyrimidine regulatory protein PyrR CPR_1817 126 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 110802056 Common - HAD hydrolase, IIB family CPR_0709 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110803918 Common - electron transfer flavoprotein beta-subunit CPR_2285 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 110803956 Common - putative aminopeptidase 2 CPR_0577 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 110802340 Common - lipoprotein, putative CPR_2614 13 COG5401 COG5401, Spore germination protein General function prediction only 110801937 Common - hypothetical protein CPR_1359 5 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 110802324 Common - hypothetical protein CPR_1592 2 None None None 110802988 Common xth exodeoxyribonuclease III CPR_1192 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 110801939 Common - transcriptional regulator, LacI family CPR_2335 129 COG1609 PurR, Transcriptional regulators Transcription 110801528 Common - Ser/Thr protein phosphatase family protein CPR_0620 17 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 110803900 Common - ABC transporter (ATP binding protein)-like protein lmo1063 CPR_2079 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110802599 Common pyrB aspartate carbamoyltransferase catalytic subunit CPR_1201 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 110803633 Common gpmI phosphoglyceromutase CPR_1298 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 110803133 Common prfC peptide chain release factor 3 CPR_0581 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 110802818 Common - conserved hypothetical protein TIGR00044 CPR_1822 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 110803717 Common - transporter-like protein lin1189 CPR_0580 75 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 110803991 Common thiI thiamine biosynthesis/tRNA modification protein ThiI CPR_1402 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 110803628 Common - bacterial type II secretion system protein F CPR_2271 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 110803344 Common - BFD-like 2Fe-2S binding domain protein CPR_0012 72 COG0579 COG0579, Predicted dehydrogenase General function prediction only 110802064 Common dhaG glycerol dehydratase reactivation factor, small subunit CPR_1008 2 None None None 110802579 Common - Mg(2+) transport ATPase protein B mgtB CPR_0990 27 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110802451 Pathogen - hypothetical protein CPR_1949 1 None None None 110802658 Common - sugar isomerase domain protein AgaS CPR_2644 47 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 110802669 Common recN DNA repair protein RecN CPR_1783 223 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 110803711 Common - hypothetical protein CPR_0865 4 None None None 110803115 Common - lipase-like protein lmo0110 CPR_0724 120 COG0657 Aes, Esterase/lipase Lipid metabolism 110801774 Common topA DNA topoisomerase I CPR_1674 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110801944 Common yabP sporulation protein YabP CPR_2486 13 None None None 110803533 Common - polysaccharide deacetylase family protein CPR_0810 93 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110803180 Common - hypothetical protein CPR_0153 15 None None None 110802544 Pathogen - hypothetical protein CPR_0939 1 None None None 110801563 Common - phosphotransferase system enzyme II, ptcA CPR_2600 30 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 110803618 Common - peptidase, M23/M37 family CPR_0189 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110802480 Common - Na/H antiporter (napA) CPR_0227 168 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110802642 Common - Hydrogenase subunit (ferredoxin) CPR_0261 29 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110803387 Common - hypothetical protein CPR_1180 1 None None None 110803362 Common - chain length determinant protein CPR_0452 32 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 110803602 Common - comE operon protein 1, putative CPR_2087 116 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 110803230 Common - Cell envelope-related transcriptional attenuator domain family CPR_1881 62 COG1316 LytR, Transcriptional regulator Transcription 110803587 Common - hypothetical protein CPR_2065 34 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 110802248 Common - hypothetical protein CPR_2126 86 COG4717 COG4717, Uncharacterized conserved protein Function unknown 110803909 Common - [2Fe-2S]-binding domain protein CPR_2551 4 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 161763553 Common rpmE 50S ribosomal protein L31 CPR_2179 188 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 110801896 Common nirC nitrite transporter CPR_1429 97 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 110803239 Common - hypothetical protein CPR_0892 31 COG1479 COG1479, Uncharacterized conserved protein Function unknown 110802080 Common - hypothetical protein CPR_0699 49 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 110803055 Common - ABC transporter permease protein CPR_2366 77 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110803426 Common rplD 50S ribosomal protein L4 CPR_2398 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 110803540 Common citF citrate lyase, alpha subunit CPR_1165 33 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 110803929 Common pabA para-aminobenzoate synthase glutamine amidotransferase, component II CPR_1093 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 110803035 Common - DedA family protein CPR_0310 133 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110801593 Common - PPIC-type PPIASE domain protein CPR_0253 168 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 110803436 Common luxS S-ribosylhomocysteinase CPR_0167 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 110802853 Common - PTS system CPR_2581 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 110802566 Common - hypothetical protein CPR_1729 160 COG1496 COG1496, Uncharacterized conserved protein Function unknown 110802011 Common - probable transmembrane transport protein CPR_0542 178 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110802018 Common alr alanine racemase CPR_0852 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 110803985 Common - uracil transporter CPR_1486 143 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110802028 Pathogen - hypothetical protein CPR_0536 1 None None None 110802241 Common rpsU 30S ribosomal protein S21 CPR_1995 112 None None None 110803175 Common hpt hypoxanthine phosphoribosyltransferase CPR_1928 144 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 110801902 Common - hypothetical protein CPR_2119 81 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 110802720 Common - hypothetical protein CPR_0952 10 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110802359 Common - hypothetical protein CPR_0111 2 None None None 110802037 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CPR_0690 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 110802214 Common feoB ferrous iron transport protein B CPR_0970 194 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 110802885 Pathogen - hypothetical protein CPR_0439 1 None None None 110803830 Common - hypothetical protein CPR_1376 2 None None None 110803261 Common - ATP-dependent metalloprotease FtsH CPR_2472 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 110803276 Common - coproporphyrinogen III oxidase CPR_2008 215 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 110803399 Common crt 3-hydroxybutyryl-CoA dehydratase CPR_2287 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110803334 Common yunB sporulation protein YunB CPR_1929 14 None None None 110801640 Common rplF 50S ribosomal protein L6 CPR_2384 234 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 110802729 Common pabB para-aminobenzoate synthase, component I CPR_1094 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 110803082 Common - probable membrane protein STY3230, putative CPR_1970 19 None None None 110802912 Common virS sensor histidine kinase VirS CPR_1481 10 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 110802174 Common - ISCpe2, transposase orfB CPR_0245 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803390 Common clpP clp protease CPR_1649 43 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110802200 Common hsp90 heat shock protein 90 CPR_0413 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 110803167 Common - HRDC domain protein CPR_0664 42 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 110801790 Common - Polysaccharide deacetylase family CPR_1521 72 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110801995 Common feoB ferrous iron transport protein B CPR_1631 190 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 110801637 Common - hypothetical protein CPR_1662 169 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 110802870 Common - tetracycline resistance protein, putative CPR_1279 180 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110803199 Common moaC molybdenum cofactor biosynthesis protein C CPR_2052 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110801477 Common - sucrose-6-phosphate hydrolase e1 CPR_0908 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 110802209 Common maa maltose transacetylase CPR_2590 86 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110803818 Common - putative D-3-phosphoglycerate dehydrogenase CPR_0064 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110803607 Common moeA molybdenum cofactor biosynthesis protein MoeA CPR_1763 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110802316 Common - arginine/ornithine antiporter CPR_0372 79 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110803209 Common - ISCpe5, transposase CPR_0758 27 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803552 Common recO DNA repair protein RecO CPR_1986 25 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 110802651 Common - V-type ATP synthase subunit C CPR_1611 25 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 110801658 Pathogen - putative lipoprotein CPR_1524 1 None None None 110803870 Common hemD uroporphyrinogen-III methyltransferase/synthase CPR_1421 205 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 110802785 Common msrA methionine sulfoxide reductase A CPR_2591 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110803414 Common pepT peptidase T CPR_0029 63 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110802365 Common tuf elongation factor Tu CPR_2416 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 110803147 Common - hypothetical protein CPR_0109 14 None None None 110803935 Common - radical SAM domain protein CPR_1689 90 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 110803771 Common - hypothetical protein CPR_0993 75 COG2267 PldB, Lysophospholipase Lipid metabolism 110801690 Pathogen - hypothetical protein CPR_0264 1 None None None 110803831 Common - hypothetical protein CPR_1157 17 COG1892 COG1892, Uncharacterized protein conserved in archaea Function unknown 110802502 Common - hypothetical protein CPR_2320 24 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110802623 Pathogen - polysaccharide polymerase, putative CPR_0462 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 110801667 Common - hypothetical protein CPR_0812 9 COG5522 COG5522, Predicted integral membrane protein Function unknown 110802111 Pathogen - hypothetical protein CPR_0451 1 None None None 110803462 Common - hypothetical protein CPR_1617 1 None None None 110801628 Common - HesB family selenoprotein CPR_0131 2 COG0316 IscA, Uncharacterized conserved protein Function unknown 110801447 Common - sugar transport system (permease) (binding protein dependent transporter) CPR_2050 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110803296 Common - recombination and DNA strand exchange inhibitor protein CPR_1847 202 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110802707 Common - transcriptional regulator, GntR family CPR_0436 128 COG1725 COG1725, Predicted transcriptional regulators Transcription 110802749 Common - 5'-nucleotidase, lipoprotein e(P4) family CPR_0188 27 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 110802717 Pathogen - hypothetical protein CPR_0354 2 None None None 110801641 Common pepP xaa-pro aminopeptidase CPR_2539 241 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110803733 Common - ISCpe2, transposase orfB CPR_0772 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803200 Common lysS lysyl-tRNA synthetase CPR_2467 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 110803371 Pathogen - hypothetical protein CPR_0130 1 None None None 110801752 Common - transcriptional regulator, ArsR/dinitrogenase iron-molybdenum cofactor family protein CPR_1105 53 COG1433 COG1433, Uncharacterized conserved protein Function unknown 110802807 Common coaD pantetheine-phosphate adenylyltransferase CPR_1700 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 110802318 Common - pyrophosphatase, MutT/nudix family CPR_0864 65 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110802282 Common - DNA replication protein DnaC CPR_2623 34 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 110803596 Common - ISCpe4, transposase CPR_0940 3 None None None 110801807 Common spoIID stage II sporulation protein D CPR_2158 43 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 110803677 Common - FucA CPR_1843 39 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 110802135 Common trx thioredoxin CPR_2350 230 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110803737 Common - peptidase, putative CPR_1395 82 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 110803506 Common - hypothetical protein CPR_1458 2 None None None 110802448 Common - N-acetylmuramoyl-L-alanine amidase domain protein CPR_1398 81 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110803842 Common - conserved hypothetical protein TIGR00247 CPR_1743 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 110803765 Common - argininosuccinate synthase CPR_2184 63 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 110802618 Common nifU nifU protein CPR_1754 161 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 110803268 Common - ISCpe7, transposase CPR_1537 57 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803064 Common - PemK family protein CPR_0286 62 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 110801470 Common - hypothetical protein CPR_0414 13 COG4640 COG4640, Predicted membrane protein Function unknown 110803769 Common - V-type ATP synthase subunit K CPR_1613 25 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 110802675 Common uvrA excinuclease ABC, A subunit CPR_0329 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 110802631 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CPR_2302 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 110802410 Common - glycerol uptake operon antiterminator CPR_2560 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 110803880 Common - hypothetical protein CPR_2617 1 None None None 110802832 Common trmE tRNA modification GTPase TrmE CPR_2669 230 COG0486 ThdF, Predicted GTPase General function prediction only 110801909 Common serS seryl-tRNA synthetase CPR_0014 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 110802684 Common rplJ 50S ribosomal protein L10 CPR_2410 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 110802419 Common - RNA-metabolizing metallo-beta-lactamase family protein CPR_1745 160 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 110802861 Common mreD rod shape-determining protein MreD CPR_2108 5 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110802153 Common - putative deoxyribonucleotide triphosphate pyrophosphatase CPR_2239 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 110802754 Common sipW signal peptidase I CPR_2281 34 COG2932 COG2932, Predicted transcriptional regulator Transcription 110802823 Common plc phospholipase C CPR_0041 4 None None None 110802919 Common tagA teichoic acid biosynthesis protein A CPR_1839 106 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 110801773 Common entB NLP/P60 family protein, probable enterotoxin CPR_1353 101 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 110802344 Common - ISCpe2, transposase orfA CPR_0888 6 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801492 Common spoVB stage V sporulation protein B CPR_1223 49 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110803206 Common mscL large-conductance mechanosensitive channel CPR_0163 138 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110803746 Common - hypothetical protein CPR_1484 16 COG0011 COG0011, Uncharacterized conserved protein Function unknown 110803150 Common - ABC transporter, permease protein, putative CPR_0171 31 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 110801531 Common - uncharacterized membrane protein CPR_1699 15 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 110802290 Common cphA cyanophycin synthetase CPR_2187 204 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110803864 Common - CobW/P47K family protein CPR_0042 124 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110801518 Pathogen - fibronectin type III domain protein CPR_1248 1 None None None 110803524 Pathogen - lipoprotein, putative CPR_0891 1 None None None 110803937 Common - alpha-mannosidase CPR_2049 53 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 110802291 Common - hypothetical protein CPR_1351 6 None None None 110801685 Common aspS aspartyl-tRNA synthetase CPR_1899 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801613 Common - HAD superfamily (subfamily IA) hydrolase, TIGR02254 CPR_0743 98 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110801789 Common ruvA Holliday junction DNA helicase motor protein CPR_1915 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 110801975 Common acpS 4'-phosphopantetheinyl transferase CPR_0282 122 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 110803656 Common pheS phenylalanyl-tRNA synthetase subunit alpha CPR_1852 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 110803237 Common prs phosphoribosylpyrophosphate synthetase CPR_1519 233 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110803683 Common - CDP-alcohol phosphatidyltransferase family CPR_0545 46 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110803741 Common - V-type ATP synthase subunit A CPR_1609 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 110803560 Common metG methionyl-tRNA synthetase CPR_2533 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110803015 Common - hypothetical protein CPR_2142 1 None None None 110803307 Common - oxidoreductase, 2-nitropropane dioxygenase family CPR_1061 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 110803987 Common - cell wall binding repeat domain protein CPR_0593 10 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110803796 Common - transcription regulator (AraC/XylS family) CPR_0928 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110802000 Common cls cardiolipin synthetase CPR_0345 146 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110802490 Pathogen - hypothetical protein CPR_0424 1 None None None 110803887 Common - putative lipoprotein CPR_2208 5 None None None 110802363 Common - transcriptional regulator, MarR family CPR_1032 115 COG1846 MarR, Transcriptional regulators Transcription 110801556 Common - UDP-glucose/GDP-mannose dehydrogenase family CPR_0456 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 110802947 Common - ISCpe6, transposase orfB CPR_0822 135 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 110802921 Pathogen - hypothetical protein CPR_0135 1 None None None 110803063 Common - GerA spore germination protein CPR_1053 15 None None None 110801721 Common - permease CPR_1547 135 COG2252 COG2252, Permeases General function prediction only 110801692 Common - hypothetical protein CPR_1472 5 None None None 110802649 Common - hypothetical protein CPR_1896 57 COG2966 COG2966, Uncharacterized conserved protein Function unknown 110802847 Common - hypothetical protein CPR_2634 1 None None None 110803902 Common - glycerol-3-phosphate transporter CPR_0222 153 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110801487 Common - BFD-like [2Fe-2S] binding domain family CPR_2558 116 COG0579 COG0579, Predicted dehydrogenase General function prediction only 110802396 Common - peptidase, M16 family CPR_2037 177 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110802840 Common - ISCpe2, transposase orfA CPR_1050 74 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803600 Common - hypothetical protein CPR_0816 68 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 110802583 Common - hypothetical protein CPR_0733 16 COG1106 COG1106, Predicted ATPases General function prediction only 110803590 Common - patatin-like phospholipase family protein CPR_1339 52 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 110801575 Common - lipoprotein CPR_0778 94 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110803850 Common deoC deoxyribose-phosphate aldolase CPR_2024 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 110801992 Common - glutamate racemase CPR_2572 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 110801795 Common rnc ribonuclease III CPR_1690 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 110801856 Common - hypothetical protein CPR_1621 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 110802078 Common - flavohemoprotein CPR_0756 147 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 110802535 Common - potassium uptake protein CPR_1854 136 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110803672 Pathogen - Fibronectin type III domain protein CPR_0687 1 None None None 110802467 Common - hypothetical protein CPR_2525 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110802176 Common msmK sugar ABC transporter, ATP-binding protein CPR_0907 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110802826 Common - HAD hydrolase, IIB family CPR_0583 145 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110802957 Common - aminotransferase, class V CPR_1403 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 110801453 Common - GatB/Yqey domain protein CPR_1994 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 110803103 Common - cell division protein DivIVA, putative CPR_1819 35 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 110802256 Common - coproporphyrinogen III oxidase CPR_1901 212 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 110802073 Common - DNA-binding response regulator CPR_2210 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110803514 Common rplL ribosomal protein L7/L12 CPR_2409 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 110803450 Common dhaF glycerol dehydratase reactivation factor, large subunit CPR_1007 12 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 110803972 Common - hydrolase, alpha/beta fold family CPR_2201 30 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110803303 Common - putative RNA-binding protein CPR_2093 82 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 110803787 Common rplR 50S ribosomal protein L18 CPR_2383 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 110801732 Common - capsular polysaccharide synthesis protein CPR_0240 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110802006 Common rubY rubrerythrin CPR_0840 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 110802933 Common proC pyrroline-5-carboxylate reductase CPR_2647 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 110802196 Common - Family of unknown function (DUF472) family CPR_1564 56 COG2898 COG2898, Uncharacterized conserved protein Function unknown 110801665 Common - hypothetical protein CPR_0488 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110802109 Common - antibiotic ABC transporter, ATP-binding protein CPR_0818 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110802428 Common - CRISPR-associated regulatory protein, DevR family CPR_0920 7 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 110802102 Common ribD riboflavin biosynthesis protein RibD CPR_0530 227 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 110801869 Common pyrG CTP synthetase CPR_2182 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 110802730 Common - probable endonuclease CPR_1388 1 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110803446 Pathogen - hypothetical protein CPR_0497 1 None None None 110803289 Common - transcriptional regulator, gntR family domain protein CPR_1280 84 COG2188 PhnF, Transcriptional regulators Transcription 110801846 Common - Mechanosensitive ion channel family CPR_0202 198 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110802556 Common - stage V sporulation protein D, spoVD, FtsI/pbp family CPR_1846 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110801964 Pathogen - hypothetical protein CPR_2554 1 None None None 110803876 Common ligA NAD-dependent DNA ligase LigA CPR_2245 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 110803954 Common pepD aminoacyl-histidine dipeptidase CPR_2115 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110802354 Common - lexa repressor CPR_0651 33 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 110802342 Common - probable endonuclease CPR_1387 1 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110803706 Common dinB DNA polymerase IV CPR_1538 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110801674 Common - transporter, putative CPR_0068 123 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 110801784 Common glpQ glycerophosphoryl diester phosphodiesterase CPR_0420 178 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110803609 Common sbcC exonuclease SbcC CPR_0205 133 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 110802796 Common - haloacid dehalogenase, IB family protein CPR_1188 26 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110802546 Common - hypothetical protein CPR_0040 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 110802458 Common - mechanosensitive ion channel family protein CPR_0247 209 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110803566 Common - Integral membrane protein domain protein CPR_2074 45 None None None 110802393 Common - cinnamoyl ester hydrolase CPR_0980 134 COG1733 COG1733, Predicted transcriptional regulators Transcription 110802112 Common nagE PTS system, N-acetylglucosamine-specific IIBC component CPR_0093 50 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110803185 Pathogen - hypothetical protein CPR_1184 1 None None None 110801948 Common - relA/spoT family protein CPR_0621 84 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 110802265 Pathogen - hypothetical protein CPR_0872 1 None None None 110801821 Common rplV 50S ribosomal protein L22 CPR_2394 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 110803943 Common - ErfK/YbiS/YcfS/YnhG family protein CPR_0028 12 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110803557 Pathogen - hypothetical protein CPR_1016 1 None None None 110803108 Common rnpA ribonuclease P CPR_2673 4 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 110802910 Pathogen - hypothetical protein CPR_0966 1 None None None 110803155 Common sdhB L-serine dehydratase, iron-sulfur-dependent, beta subunit CPR_2642 75 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110803474 Common - hypothetical protein CPR_0266 91 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 110803660 Common - MATE efflux family protein CPR_0828 175 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110803549 Common - hypothetical protein CPR_1516 11 COG4086 COG4086, Predicted secreted protein Function unknown 110802301 Common - methyltransferase, putative CPR_1701 215 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 110802051 Common - hypothetical protein CPR_0978 3 None None None 110802812 Common - rhodanese domain protein CPR_1557 165 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110803477 Pathogen - mutator mutT protein-like protein CPR_1187 1 None None None 110802234 Pathogen - hypothetical protein CPR_0134 1 None None None 110803585 Common - IS1470, transposase CPR_1078 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 110801950 Common - DNA topoisomerase IV subunit B CPR_2040 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110802899 Common - spore coat protein, putative CPR_2196 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110802421 Common arcC carbamate kinase CPR_0160 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 110802714 Common - pentitol PTS system enzyme II B component-like protein lmo1972 CPR_0490 34 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 110802978 Common - transcriptional regulator, TetR family CPR_0094 14 COG1309 AcrR, Transcriptional regulator Transcription 110801841 Common - periplasmic [Fe] hydrogenase 1 CPR_0938 84 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110803048 Common - uncharacterized conserved membrane protein, putative CPR_0105 9 COG5523 COG5523, Predicted integral membrane protein Function unknown 110803372 Common - aspartate aminotransferase CPR_0327 217 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110801817 Common carA carbamoyl phosphate synthase small subunit CPR_2577 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 110801607 Common - mccF-like protein CPR_2453 86 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110802035 Common - sensor histidine kinase CPR_0225 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110801716 Common - PIN/TRAM domain protein CPR_2427 45 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 110803492 Pathogen - sensory histidine kinase (with HAMP and PAS domains), putative CPR_1807 1 None None None 110803913 Common aroC chorismate synthase CPR_0691 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 110802438 Common cas6 CRISPR-associated protein Cas6 CPR_0918 4 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 110803495 Common - metallopeptidase, M24 family CPR_0854 198 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110802044 Common rpsT 30S ribosomal protein S20 CPR_2014 61 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 110802187 Common - PTS system, mannose/fructose/sorbose family, IIAB component CPR_0804 93 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 110803078 Common rplX 50S ribosomal protein L24 CPR_2388 193 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 110803685 Common - transmembrane protein Vexp3 CPR_2078 19 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110802407 Common - molybdopterin oxidoreductase CPR_1518 186 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110802289 Common fusA elongation factor G CPR_0096 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110801755 Common - transcriptional regulator, araC family domain protein CPR_0441 121 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110802904 Common - hypothetical protein CPR_2613 2 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 110803804 Common rplE 50S ribosomal protein L5 CPR_2387 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 110801924 Common - putative, lipoprotein signal peptidase CPR_0074 1 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 110803254 Common - hypothetical protein CPR_0627 2 None None None 110802935 Common ffh signal recognition particle protein CPR_1685 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 110803487 Common - ISCpe2, transposase orfB CPR_0989 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110801485 Common - ISCpe2, transposase orfA CPR_1584 71 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110803095 Common spoVAC stage V sporulation protein AC CPR_2019 15 None None None 110803226 Pathogen - hypothetical protein CPR_1378 1 None None None