Clostridium perfringens ATCC 13124, complete genome NC_008261 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 110801028 Common - nucleoside transporter, NupC family CPF_2819 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 110800424 Common rplX 50S ribosomal protein L24 CPF_2703 193 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 110800921 Pathogen - hypothetical protein CPF_1065 1 None None None 110800380 Pathogen - hypothetical protein CPF_1074 1 None None None 110799181 Common - hypothetical protein CPF_0540 1 None None None 110801373 Common spoVT stage V sprulation protein T CPF_2805 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110801212 Common rbsA ribose ABC transporter, ATP-binding protein CPF_1882 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110799842 Common speE spermidine synthase CPF_0529 128 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 110800076 Common - hypothetical protein CPF_2928 4 None None None 110799108 Common yhaM 3'-5' exoribonuclease YhaM CPF_0027 46 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 110798736 Common sigH RNA polymerase factor sigma-70 CPF_2732 38 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110799484 Common - putative DNA replication protein DnaD CPF_2939 8 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 110798603 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CPF_2933 226 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 110799102 Common - CBS domain protein CPF_2269 22 COG0517 COG0517, FOG: CBS domain General function prediction only 110800434 Common - CBS domain protein CPF_2421 30 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110799361 Common prmA ribosomal protein L11 methyltransferase CPF_2284 191 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 110798945 Common kdpE DNA-binding response regulator KdpE CPF_1214 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110799507 Common - small, acid-soluble spore protein 1 CPF_2417 12 None None None 110800378 Common - putative transcriptional regulator CPF_2601 3 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 110800352 Common - metallopeptidase, M24 family CPF_0866 197 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110799256 Common - hypothetical protein CPF_0246 4 None None None 110799500 Common - rubrerythrin family protein CPF_2637 4 COG1633 COG1633, Uncharacterized conserved protein Function unknown 110800371 Common - RNA pseudouridine synthase family protein CPF_2546 200 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110800833 Common dacF D-alanyl-D-alanine carboxypeptidase CPF_2376 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110798757 Pathogen - hypothetical protein CPF_0524 1 None None None 110800324 Common - rubrerythrin CPF_1538 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 110799777 Common proC pyrroline-5-carboxylate reductase CPF_2969 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 110800314 Common - single-strand DNA-binding protein CPF_0283 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110799065 Pathogen - hypothetical protein CPF_1219 1 None None None 110798806 Common glmU UDP-N-acetylglucosamine pyrophosphorylase CPF_2813 239 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 110800150 Pathogen - hypothetical protein CPF_1083 1 None None None 110799244 Common - hypothetical protein CPF_1372 18 COG2364 COG2364, Predicted membrane protein Function unknown 110800212 Common rnhB ribonuclease HII CPF_1960 211 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 110801113 Common - fliB domain protein CPF_0986 6 None None None 110800447 Common - CDP-alcohol phosphatidyltransferase family protein CPF_0561 48 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110798950 Common - hypothetical protein CPF_2929 21 None None None 110800039 Common - dnaJ domain protein CPF_0239 4 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110801209 Common - HAD-superfamily hydrolase, subfamily IB CPF_0237 37 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110800550 Common - membrane protein, MmpL family CPF_0591 72 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 110799205 Common - putative adenine deaminase CPF_1476 78 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 110801082 Common - phage terminase, small subunit CPF_0948 21 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 110800887 Pathogen - hypothetical protein CPF_1147 1 None None None 110799772 Common recA recombinase A CPF_1927 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 110800248 Common - hypothetical protein CPF_0968 1 None None None 110798946 Common rbsC ribose ABC transporter, permease protein CPF_1881 122 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110800275 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CPF_2476 200 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 110800889 Common xseA exodeoxyribonuclease VII large subunit CPF_2076 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 110800880 Common - V-type ATP synthase subunit F CPF_1891 9 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 110799348 Common - transcriptional regulator, Crp/Fnr family CPF_0781 181 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110801118 Common - DNA-binding protein CPF_2222 102 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 110800353 Common - stage II sporulation protein R CPF_2475 15 None None None 110799082 Common - hypothetical protein CPF_2254 2 None None None 110800616 Common - transcriptional regulator, Crp/Fnr family CPF_1694 104 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110800288 Pathogen - hypothetical protein CPF_1254 1 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 110800743 Common brnQ branched-chain amino acid transport system II carrier protein CPF_0613 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 110800359 Common - hypothetical protein CPF_0870 15 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110800729 Common - TspO/MBR family protein CPF_2240 63 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 110799215 Common crt 3-hydroxybutyryl-CoA dehydratase CPF_2585 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110799001 Common - transcriptional regulator, AraC family CPF_1237 102 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110800301 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CPF_2739 197 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 110800004 Common - transcription antiterminator CPF_0069 30 COG3711 BglG, Transcriptional antiterminator Transcription 110799596 Pathogen - putative lipoprotein CPF_0049 1 None None None 110801278 Common - oligopeptide/dipeptide ABC transporter, permease protein CPF_2554 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110799586 Common spoIIIAH stage III sporulation protein AH CPF_2080 3 None None None 110800095 Common - polyA polymerase family protein CPF_0026 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 110799576 Common - hypothetical protein CPF_0906 2 None None None 110799588 Common - hypothetical protein CPF_1306 1 None None None 110799966 Common rpsG 30S ribosomal protein S7 CPF_2718 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 110800440 Common lysS lysyl-tRNA synthetase CPF_2781 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 110799442 Common - hypothetical protein CPF_0995 56 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110801201 Common codY transcriptional repressor CodY CPF_1955 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 110799514 Common - acetyltransferase, GNAT family CPF_1025 3 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110799745 Common - aluminum resistance protein CPF_1362 30 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 110800469 Pathogen - hypothetical protein CPF_1345 1 None None None 110801227 Common recR recombination protein RecR CPF_0054 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 110798852 Common bioB biotin synthase CPF_1795 186 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 110800203 Common - R3H domain protein CPF_2993 69 COG1847 Jag, Predicted RNA-binding protein General function prediction only 110800970 Pathogen - hypothetical protein CPF_1591 1 None None None 110800605 Common frr ribosome recycling factor CPF_1951 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 110798837 Common - hypothetical protein CPF_2410 75 COG1479 COG1479, Uncharacterized conserved protein Function unknown 110799926 Pathogen - hypothetical protein CPF_1506 1 None None None 110798598 Common - iron chelate uptake ABC transporter, FeCT family, solute-binding protein CPF_1296 175 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110799157 Pathogen - hypothetical protein CPF_0117 1 None None None 110801153 Common - hypothetical protein CPF_2658 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 110798999 Common - MgtC family protein CPF_1155 114 COG1285 SapB, Uncharacterized membrane protein Function unknown 110798845 Pathogen - hypothetical protein CPF_1259 1 None None None 110799335 Pathogen - hypothetical protein CPF_0856 1 None None None 110799899 Common - hypothetical protein CPF_0075 1 None None None 110798907 Common spoVAF spore germination protein AF CPF_1241 15 None None None 110799804 Common - bacterial extracellular solute-binding protein CPF_2335 15 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110800486 Common - hypothetical protein CPF_0157 15 None None None 110800238 Common rnr ribonuclease R CPF_1502 200 COG0557 VacB, Exoribonuclease R Transcription 110798729 Common aspB aspartate aminotransferase CPF_1924 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110799974 Common - putative DNA-binding protein CPF_1593 1 None None None 110800193 Common - cell wall surface anchor family protein CPF_0123 14 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110799351 Common thiS thiamine biosynthesis protein ThiS CPF_1856 14 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 110798815 Common - hypothetical protein CPF_2358 34 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 110799114 Common - tetrapyrrole methylase family protein CPF_0276 213 COG0313 COG0313, Predicted methyltransferases General function prediction only 110801270 Pathogen - hypothetical protein CPF_0097 1 None None None 110799040 Common - hypothetical protein CPF_0183 1 None None None 110799408 Pathogen - hypothetical protein CPF_1868 1 None None None 110798722 Common - sensor histidine kinase CPF_2640 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110800559 Common - ascorbate-specific PTS system enzyme IIC CPF_0645 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 110798773 Common cfa cyclopropane-fatty-acyl-phospholipid synthase CPF_1307 137 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110799912 Common - hypothetical protein CPF_2623 2 None None None 110800513 Common - hypothetical protein CPF_0726 53 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 110801261 Common - bacitracin ABC transporter, ATP-binding protein CPF_1193 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110799076 Common alaS alanyl-tRNA synthetase CPF_2033 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110799835 Common - hypothetical protein CPF_0609 78 COG2510 COG2510, Predicted membrane protein Function unknown 110799762 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase CPF_0673 198 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 110800986 Common - fructose-bisphosphate aldolase CPF_0081 180 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 110798879 Common - Cna protein B-type domain protein CPF_0122 9 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110800992 Common - amino acid permease family protein CPF_1217 55 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110799188 Common - glycosyl transferase, group 1 CPF_0478 39 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800260 Common - hypothetical protein CPF_2199 5 None None None 110800643 Common rpsC 30S ribosomal protein S3 CPF_2708 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 110801002 Common - putative membrane-associated zinc metalloprotease CPF_1947 220 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 110801237 Common - glycine betaine/L-proline transport, ATP-binding protein CPF_0537 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 110799933 Common ruvB Holliday junction DNA helicase B CPF_2203 236 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 110799373 Common pstA phosphate ABC transporter, permease protein PstA CPF_0620 234 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110799626 Common truB tRNA pseudouridine synthase B CPF_1937 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 110800024 Pathogen - BFD-like iron-sulfur cluster-binding protein CPF_0444 1 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110798963 Common panE 2-dehydropantoate 2-reductase CPF_0788 128 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 110799049 Common - hypothetical protein CPF_1182 4 COG2717 COG2717, Predicted membrane protein Function unknown 110801251 Common eutS ethanolamine utilization protein EutS CPF_0886 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 110799732 Common galU UTP-glucose-1-phosphate uridylyltransferase CPF_0483 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110801405 Pathogen - hypothetical protein CPF_1130 1 None None None 110801236 Common nadA quinolinate synthetase CPF_0382 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 110799713 Common - hypothetical protein CPF_2032 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 110798798 Common - hypothetical protein CPF_2753 20 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 110799012 Common - GIY-YIG domain protein CPF_1697 88 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 110800876 Common - putative hyaluronoglucosaminidase CPF_0875 15 None None None 110798867 Common era GTP-binding protein Era CPF_2272 233 COG1159 Era, GTPase General function prediction only 110799893 Common - oxidoreductase, FAD/FMN-binding CPF_0697 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 110800728 Common - putative transketolase, N-terminal subunit CPF_0292 223 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 110801187 Common - cytidine/deoxycytidylate deaminase family protein CPF_1322 92 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 110799951 Common def polypeptide deformylase CPF_1997 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 110799022 Common - hypothetical protein CPF_2002 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 110798981 Common - CobW/P47K family protein CPF_0043 123 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110800696 Common nanA N-acetylneuraminate lyase CPF_0178 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110798939 Common sigE sporulation sigma factor SigE CPF_2015 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110799614 Common rph ribonuclease PH CPF_2536 211 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 110799354 Common - hypothetical protein CPF_2653 17 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 110801139 Pathogen - hypothetical protein CPF_0976 1 None None None 110799088 Pathogen - hypothetical protein CPF_2090 1 None None None 110799477 Common - hypothetical protein CPF_1461 26 COG4760 COG4760, Predicted membrane protein Function unknown 110798582 Common - hypothetical protein CPF_0290 1 None None None 110800586 Common - hypothetical protein CPF_2595 142 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 110801091 Common - cyclic nucleotide-binding domain protein CPF_0336 56 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110798567 Common - hypothetical protein CPF_0110 3 None None None 110801416 Common - hypothetical protein CPF_2797 62 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 110799740 Common - putative glycolate oxidase, subunit GlcD CPF_0310 203 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110798702 Common - hypothetical protein CPF_0430 1 None None None 110800089 Common - polysaccharide deacetylase family protein CPF_0823 92 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110801135 Common - amino acid permease family protein CPF_0321 192 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801098 Pathogen - hypothetical protein CPF_0907 1 None None None 110800149 Pathogen - hypothetical protein CPF_1869 1 None None None 110799985 Common mbl mbl protein CPF_2445 185 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 110799388 Pathogen - hypothetical protein CPF_0463 1 None None None 110799091 Pathogen - hypothetical protein CPF_0698 1 None None None 110798956 Common - putative type II restriction endonuclease CPF_0140 4 None None None 110800915 Common - ABC transporter, ATP-binding protein CPF_0118 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110800542 Common - Ser/Thr protein phosphatase family protein CPF_2416 102 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 110800414 Common - ABC transporter, ATP-binding protein CPF_0136 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110800573 Pathogen - hypothetical protein CPF_0153 1 None None None 110800784 Common - transposase, IS605 OrfB family CPF_0871 71 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110800639 Pathogen - hypothetical protein CPF_2256 1 None None None 110801021 Common - hypothetical protein CPF_2172 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 110800123 Common smpB SsrA-binding protein CPF_1501 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 110799684 Common - putative ABC transporter, permease protein CPF_0174 32 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 110799175 Common - transcriptional regulator, DeoR family CPF_0566 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110800399 Common - polysaccharide deacetylase family protein CPF_1728 111 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110800120 Common - polysaccharide deacetylase family protein CPF_1758 73 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110800776 Common cotS spore coat protein CotS CPF_2482 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110799651 Pathogen - hypothetical protein CPF_0513 1 None None None 110799223 Common - hypothetical protein CPF_1569 1 COG4865 COG4865, Glutamate mutase epsilon subunit Amino acid transport and metabolism 110801313 Common - MiaB-like tRNA modifying enzyme CPF_2282 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110799560 Common - NIF3 family protein CPF_2261 157 COG0327 COG0327, Uncharacterized conserved protein Function unknown 110800418 Common trx thioredoxin CPF_0737 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110799943 Common glyA serine hydroxymethyltransferase CPF_2184 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 110801427 Common - ethanolamine ammonia-lyase, large subunit CPF_0891 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 110800661 Common - endodeoxyribonuclease RusA family protein CPF_0942 14 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 110801355 Common - MATE efflux family protein CPF_1711 152 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110799573 Common - MATE efflux family protein CPF_1735 127 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110799325 Pathogen - hypothetical protein CPF_0702 1 None None None 110799858 Pathogen - hypothetical protein CPF_2543 1 None None None 110799316 Common - CAAX amino terminal protease family protein CPF_0998 60 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 110800625 Common - capA domain protein CPF_1917 59 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 110800255 Common - transcriptional regulator, GntR family CPF_1491 85 COG2188 PhnF, Transcriptional regulators Transcription 110801038 Common oxaA putative inner membrane protein translocase component YidC CPF_2994 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 110800677 Pathogen - hypothetical protein CPF_0494 1 None None None 110800431 Common purR purine operon repressor CPF_2815 48 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110798791 Common - type III restriction-modification system, Mod subunit CPF_0361 91 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 110799261 Common - hypothetical protein CPF_1741 4 None None None 110800673 Common - transcriptional regulator, MarR family CPF_0791 139 COG1846 MarR, Transcriptional regulators Transcription 110800156 Pathogen - hypothetical protein CPF_1036 1 None None None 110800201 Common - hypothetical protein CPF_2500 25 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110800172 Common - hypothetical protein CPF_1699 3 None None None 110800638 Common ldh L-lactate dehydrogenase CPF_0098 165 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 110801120 Pathogen - hypothetical protein CPF_1639 1 None None None 110800789 Common - CAAX amino terminal protease family protein CPF_0131 24 None None None 110800179 Common - ArsC family protein CPF_2672 82 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 110801054 Common - hypothetical protein CPF_1747 35 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 110799301 Common - BRO domain protein CPF_0930 8 COG3617 COG3617, Prophage antirepressor Transcription 110800071 Common - ethanolamine utilization protein CPF_0894 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 110800364 Pathogen - hypothetical protein CPF_1078 1 None None None 110800793 Common - transglutaminase domain protein CPF_2177 33 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 110799137 Common ribH riboflavin synthase subunit beta CPF_0549 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 110800189 Common - hypothetical protein CPF_1680 28 COG3819 COG3819, Predicted membrane protein Function unknown 110801391 Common - hypothetical protein CPF_1808 9 COG4129 COG4129, Predicted membrane protein Function unknown 110798631 Common - ribonuclease, Rne/Rng family CPF_2386 187 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 110800770 Pathogen - hypothetical protein CPF_0438 1 COG4980 GvpP, Gas vesicle protein General function prediction only 110798719 Common - response regulator CPF_0512 223 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 110800397 Common hemL glutamate-1-semialdehyde aminotransferase CPF_1685 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 110801298 Common - tetratricopeptide repeat protein CPF_2243 102 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 110798712 Common - MATE efflux family protein CPF_0857 182 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110799272 Common - DJ-1 family protein CPF_2324 126 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 110801071 Common rluB ribosomal small subunit pseudouridine synthase B CPF_1336 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110799414 Common obgE GTPase ObgE CPF_2382 249 COG0536 Obg, Predicted GTPase General function prediction only 110798706 Common - hypothetical protein CPF_1200 2 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 110798870 Common atpF ATP synthase F0, B subunit CPF_2456 47 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 110801241 Common - transcriptional repressor CPF_2754 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 110801328 Common - discoidin domain protein CPF_1073 18 None None None 110801000 Common - hypothetical protein CPF_0343 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 110799524 Common - phospholipase, patatin family CPF_1546 54 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 110799243 Pathogen - hypothetical protein CPF_0692 1 None None None 110799853 Common infC translation initiation factor IF-3 CPF_2146 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 110798649 Common - biotin synthase CPF_2775 194 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 110799394 Common gldA glycerol dehydrogenase CPF_0094 93 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 110801376 Common dnaK chaperone protein DnaK CPF_2290 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 110800649 Common gdhA glutamate dehydrogenase CPF_1770 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 110799885 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III CPF_1324 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 110801281 Common - transcriptional regulator, GntR family CPF_0374 99 COG2188 PhnF, Transcriptional regulators Transcription 110801178 Common rplL ribosomal protein L7/L12 CPF_2723 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 110800493 Common - putative oxidoreductase CPF_0371 31 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 110799406 Common - hypothetical protein CPF_0248 2 None None None 110801175 Common - cobalt ABC transporter, ATP-binding protein CPF_2683 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110801419 Common gpmI phosphoglyceromutase CPF_1508 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 110800385 Common - membrane protein CPF_2861 155 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 110800946 Common - transcriptional regulator, Cro/CI family CPF_0928 3 COG1396 HipB, Predicted transcriptional regulators Transcription 110800168 Pathogen - hypothetical protein CPF_1702 1 None None None 110799386 Common - LysM domain protein CPF_0880 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110799541 Common - nitroreductase family protein CPF_0176 90 COG0778 NfnB, Nitroreductase Energy production and conversion 110799383 Common - Ser/Thr protein phosphatase family protein CPF_2534 62 COG0622 COG0622, Predicted phosphoesterase General function prediction only 110798894 Common - ABC transporter, ATP-binding protein CPF_0830 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110799505 Common iadA isoaspartyl dipeptidase CPF_2665 34 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110800845 Common - choloylglycine hydrolase family protein CPF_1348 37 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 110800933 Common ytvI sporulation integral membrane protein YtvI CPF_2984 12 COG0628 PerM, Predicted permease General function prediction only 110801089 Pathogen - hypothetical protein CPF_0666 1 None None None 110798625 Common - iron-sulfur cluster-binding protein CPF_0220 2 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110799607 Common - sodium:dicarboxylate symporter family CPF_1191 164 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 110800951 Pathogen - hypothetical protein CPF_0515 1 None None None 110799699 Common - precorrin-2 dehydrogenase CPF_1689 3 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 110800478 Common - putative alpha-mannosidase CPF_2337 53 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 110798896 Common - von Willebrand factor type A domain protein CPF_0497 6 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 110798693 Common - single-strand DNA-binding protein CPF_1595 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110801031 Common - hypothetical protein CPF_0046 2 COG3689 COG3689, Predicted membrane protein Function unknown 110799645 Common - amino acid ABC transporter, ATP-binding protein CPF_2349 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110798994 Common - sensor histidine kinase CPF_1402 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110799437 Common gyrB DNA gyrase subunit B CPF_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110799711 Common - V-type ATP synthase subunit I CPF_1895 50 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 110801023 Common - hypothetical protein CPF_1105 4 None None None 110800539 Pathogen - hypothetical protein CPF_0334 1 None None None 110799824 Common - alcohol dehydrogenase, iron-containing CPF_0451 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110800115 Common - hydrolase, NUDIX family CPF_0749 83 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 110799190 Common - phage portal protein, HK97 family CPF_1586 57 COG4695 COG4695, Phage-related protein Function unknown 110799296 Common - hypothetical protein CPF_1944 170 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 110800473 Common - ABC transporter, ATP-binding protein CPF_0267 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110799727 Common - putative lipoprotein CPF_2883 1 None None None 110800902 Common - hypothetical protein CPF_1184 5 None None None 110800804 Pathogen - hypothetical protein CPF_0758 1 None None None 110799030 Common - hypothetical protein CPF_1841 3 None None None 110801141 Common - putative hyaluronoglucosaminidase CPF_1487 24 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110799516 Common argG argininosuccinate synthase CPF_0683 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 110800080 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CPF_1768 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110800822 Common - hypothetical protein CPF_2109 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 110801162 Common - UBA/TS-N domain protein CPF_1054 1 None None None 110799226 Pathogen - hypothetical protein CPF_2761 1 None None None 110799197 Common - acetyltransferase, GNAT family CPF_0724 47 COG0456 RimI, Acetyltransferases General function prediction only 110799703 Pathogen - hypothetical protein CPF_1149 1 None None None 110799709 Common cstA carbon starvation protein CstA CPF_0741 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 110801166 Common metG methionyl-tRNA synthetase CPF_2847 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801389 Pathogen - hypothetical protein CPF_1022 1 None None None 110800452 Common - transcriptional regulator, MarR family CPF_1494 94 COG1846 MarR, Transcriptional regulators Transcription 110801436 Common - cell envelope-related transcriptional attenuator domain protein CPF_2378 64 COG1316 LytR, Transcriptional regulator Transcription 110800280 Pathogen - hypothetical protein CPF_1099 1 None None None 110800740 Common - Mur ligase family protein CPF_2756 118 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110800857 Common - oxidoreductase, short-chain dehydrogenase/reductase family CPF_2906 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110799637 Common - V-type ATP synthase subunit B CPF_1889 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 110801107 Common - xanthine/uracil permease family protein CPF_2907 167 COG2252 COG2252, Permeases General function prediction only 110799493 Pathogen - hypothetical protein CPF_0496 1 None None None 110798650 Common clpB clpB protein CPF_1681 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 110798620 Common - hypothetical protein CPF_1907 25 COG2155 COG2155, Uncharacterized conserved protein Function unknown 110800926 Common galE UDP-glucose 4-epimerase CPF_0282 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 110799692 Pathogen - hypothetical protein CPF_1218 1 None None None 110798602 Common - iron(III) ABC transporter, iron(III)-binding protein CPF_1426 132 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110798738 Common - hypothetical protein CPF_2986 13 None None None 110800650 Common - nucleotidyl transferase family protein CPF_0610 178 COG4750 LicC, CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes Cell envelope biogenesis, outer membrane 110799837 Common - hypothetical protein CPF_1570 2 None None None 110799363 Common - hypothetical protein CPF_0517 2 None None None 110799148 Pathogen - hypothetical protein CPF_1458 1 None None None 110799531 Common sbcC exonuclease SbcC CPF_0207 115 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 110800523 Common mraW S-adenosyl-methyltransferase MraW CPF_2119 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 110800063 Common - hypothetical protein CPF_2844 44 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 110798782 Common - hypothetical protein CPF_1712 4 None None None 110801194 Common rpsR 30S ribosomal protein S18 CPF_2976 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 110800815 Common kduI 5-keto-4-deoxyuronate isomerase CPF_0399 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 110799186 Common plsD sn-glycerol-3-phosphate acyltransferase CPF_1526 88 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110800891 Pathogen - hypothetical protein CPF_0158 1 None None None 110800735 Common nanE N-acetylmannosamine-6-phosphate 2-epimerase CPF_0177 45 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 110799159 Common - hypothetical protein CPF_1303 1 None None None 110800702 Common - metallo-beta-lactamase family protein CPF_2191 224 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110798619 Common - PP-loop family protein CPF_1746 157 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110799452 Common metG methionyl-tRNA synthetase CPF_2846 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110798905 Common - sensory box histidine kinase CPF_1523 224 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110800753 Common - sensor histidine kinase CPF_0499 25 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 110800402 Common - ABC transporter, permease/ATP-binding protein CPF_0507 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110798973 Common speB agmatinase CPF_0530 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 110800898 Pathogen - hypothetical protein CPF_1120 1 None None None 110800865 Common gpr germination protease CPF_2298 15 None None None 110800561 Common - putative N-acetylmuramoyl-L-alanine amidase CPF_0545 27 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 110801198 Common - EAL domain protein CPF_1064 173 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110801249 Common - hypothetical protein CPF_1567 9 None None None 110801129 Common - ABC transporter, permease protein CPF_0558 178 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110800422 Common pepT peptidase T CPF_0029 63 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110799455 Common arcD arginine/ornithine antiporter CPF_0163 163 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110800191 Common - sugar ABC transporter, permease protein CPF_1115 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110800105 Common rnfA electron transport complex, RnfABCDGE type, A subunit CPF_1320 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 110801125 Pathogen - hypothetical protein CPF_0059 1 None None None 110801371 Pathogen - hypothetical protein CPF_0141 1 None None None 110800135 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II CPF_1327 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110799897 Common rpoZ DNA-directed RNA polymerase subunit omega CPF_2000 33 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 110801068 Common - Ser/Thr protein phosphatase family protein CPF_0379 66 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 110798685 Common - cation efflux family protein CPF_0586 218 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110798881 Common - hypothetical protein CPF_2951 1 None None None 110799630 Common - ABC transporter, ATP-binding protein CPF_1757 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110801111 Common bcd butyryl-CoA dehydrogenase CPF_2584 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110799067 Common pabB para-aminobenzoate synthase, component I CPF_1272 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 110799055 Common uvrB excinuclease ABC subunit B CPF_0300 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 110801219 Common - conserved hypothetical protein TIGR00275 CPF_1339 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 110801096 Common - transcriptional regulator, AraC family CPF_1111 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110800717 Common rbfA ribosome-binding factor A CPF_1939 160 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 110799753 Common gshAB bifunctional glutamate--cysteine ligase/glutathione synthetase CPF_1825 96 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 110801301 Common - putative phage terminase, large subunit CPF_0949 6 None None None 110799554 Common - iron-sulfur cluster-binding protein, rieske family CPF_0767 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110799997 Common - hypothetical protein CPF_2465 1 None None None 110800694 Pathogen - hypothetical protein CPF_0974 1 None None None 110801348 Common - transposase, IS605 OrfB family CPF_1629 71 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110800587 Pathogen - hypothetical protein CPF_1773 1 None None None 110799562 Common - secretion system protein E CPF_2570 223 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 110800666 Common - phnA family protein CPF_2917 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 110801080 Common pspA phage shock protein A CPF_1822 71 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 110799037 Pathogen - hypothetical protein CPF_2918 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110800014 Common - ABC transporter, ATP-binding protein CPF_0878 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110799213 Common - pyrophosphatase, MutT/nudix family CPF_0882 65 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110800098 Common - ABC transporter, ATP-binding protein CPF_1094 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110799346 Common - stage 0 sporulation protein J CPF_2987 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 110798937 Common - ROK family protein CPF_0731 127 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110800236 Pathogen - hypothetical protein CPF_2053 1 COG4640 COG4640, Predicted membrane protein Function unknown 110798860 Common - hypothetical protein CPF_0947 7 None None None 110800613 Common - putative exo-alpha-sialidase CPF_0532 18 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 110799548 Pathogen - hypothetical protein CPF_2602 1 None None None 110800411 Common - hypothetical protein CPF_2831 14 None None None 110799964 Common - transcriptional regulator, AbrB family CPF_0277 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110800445 Common - fructokinase CPF_1782 172 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110799990 Common - glycosyl hydrolase, family 20 CPF_1238 52 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 110799584 Common - hypothetical protein CPF_0360 4 None None None 110800408 Common nagB glucosamine-6-phosphate deaminase CPF_2744 87 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 110799323 Common mtfB mannosyltransferase B CPF_2483 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800488 Common - small acid-soluble spore protein CPF_2159 8 None None None 110799489 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CPF_1289 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 110799236 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase CPF_1948 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 110800030 Common - hypothetical protein CPF_0234 9 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 110801224 Common nifJ pyruvate-flavodoxin oxidoreductase CPF_2318 121 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 110800606 Common - PTS system, mannose/fructose/sorbose family, IIB component CPF_0818 93 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 110800484 Common - putative spore coat protein CPF_2267 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110798920 Common - amidohydrolase-like protein CPF_2765 56 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110801225 Common - hypothetical protein CPF_2979 27 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 110798958 Common - putative 1-acyl-sn-glycerol-3-phosphate acyltransferase CPF_1671 205 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110800008 Common ftsY signal recognition particle-docking protein FtsY CPF_1969 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 110801101 Common - hypothetical protein CPF_2259 18 None None None 110800320 Pathogen - hypothetical protein CPF_0196 1 None None None 110798835 Common ackA acetate kinase CPF_1977 162 COG0282 ackA, Acetate kinase Energy production and conversion 110799844 Common - lysine-N-methylase-like protein CPF_1156 6 None None None 110799648 Common minC septum formation inhibitor CPF_2394 112 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 110798859 Common - hypothetical protein CPF_1704 13 COG3339 COG3339, Uncharacterized conserved protein Function unknown 110800222 Common - hypothetical protein CPF_1677 14 COG2105 COG2105, Uncharacterized conserved protein Function unknown 110801253 Common - hypothetical protein CPF_0150 25 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110799078 Common - peptidase, U32 family CPF_2136 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 110799512 Common - transcriptional regulator, GntR family CPF_2963 139 COG2188 PhnF, Transcriptional regulators Transcription 110801308 Common - glycoprotease family protein CPF_2423 185 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 110801173 Common - glycosyl transferase, group 1 family protein CPF_0266 53 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800205 Pathogen - hypothetical protein CPF_0961 1 None None None 110800557 Common - FAD-dependent oxidoreductase CPF_0012 73 COG0579 COG0579, Predicted dehydrogenase General function prediction only 110800006 Common adk adenylate kinase CPF_2693 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 110799333 Common - hypothetical protein CPF_2691 3 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 110799131 Common - alcohol dehydrogenase, iron-containing CPF_0080 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110800549 Common - oligopeptide/dipeptide ABC transporter, ATP-binding protein CPF_2552 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110800157 Common ileS isoleucyl-tRNA synthetase CPF_2865 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801203 Common - hypothetical protein CPF_0485 3 None None None 110798635 Common - sensor histidine kinase CPF_2241 215 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110800059 Common radC DNA repair protein RadC CPF_2399 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 110800495 Pathogen - hypothetical protein CPF_0203 1 None None None 110800174 Common - hypothetical protein CPF_2624 1 COG1403 McrA, Restriction endonuclease Defense mechanisms 110800955 Common phoU phosphate transport system regulatory protein PhoU CPF_0622 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110799519 Common - mechanosensitive ion channel family protein CPF_0204 198 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110799165 Common rpsL 30S ribosomal protein S12 CPF_2719 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 110799308 Common - transcriptional regulator, PadR family CPF_0699 64 COG1695 COG1695, Predicted transcriptional regulators Transcription 110799155 Common - MATE efflux family protein CPF_2859 138 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110799770 Common leuS leucyl-tRNA synthetase CPF_0657 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801016 Common sleC spore cortex-lytic enzyme SleC CPF_2885 2 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 110798571 Common - anaerobic sulfite reductase subunit B CPF_1788 125 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110800681 Common - acylphosphatase CPF_2228 71 COG1254 AcyP, Acylphosphatases Energy production and conversion 110801387 Common cobJ precorrin-3B C17-methyltransferase CPF_1428 187 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 110799095 Common - hypothetical protein CPF_2675 81 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110799643 Common - dihydroxyacetone kinase family protein CPF_0095 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 110800343 Common topA DNA topoisomerase I CPF_1956 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110801213 Common argF ornithine carbamoyltransferase CPF_0162 235 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 110798788 Common gcp O-sialoglycoprotein endopeptidase CPF_2496 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 110800316 Common - ybaK/ebsC protein CPF_1566 111 COG2606 EbsC, Uncharacterized conserved protein Function unknown 110800276 Pathogen - hypothetical protein CPF_2860 1 None None None 110800326 Common - peptidase, M16 family CPF_2323 163 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110798584 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CPF_0342 207 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 110799768 Common - phosphoribosylformylglycinamidine synthase CPF_0671 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 110800297 Common fruA PTS system, fructose-specific, IIABC component CPF_0564 145 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 110801375 Common - hypothetical protein CPF_0231 43 None None None 110800327 Common manA mannose-6-phosphate isomerase, class I CPF_1391 48 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 110801109 Common - formate/nitrite transporter family protein CPF_0089 92 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 110800290 Common - beta-galactosidase CPF_0160 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 110799246 Common - transcriptional regulator, MarR family CPF_0521 1 COG1846 MarR, Transcriptional regulators Transcription 110800575 Pathogen - mutator mutT-like protein CPF_1374 1 None None None 110799678 Common carA carbamoyl phosphate synthase small subunit CPF_2898 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 110800831 Common - hydrolase, alpha/beta fold family CPF_2495 32 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110799029 Common - hypothetical protein CPF_1555 71 COG2323 COG2323, Predicted membrane protein Function unknown 110800436 Pathogen - hypothetical protein CPF_1594 1 None None None 110800093 Common infA translation initiation factor IF-1 CPF_2690 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 110798613 Common fucO L-1,2-propanediol oxidoreductase CPF_1046 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110798804 Pathogen - hypothetical protein CPF_0589 1 None None None 110798578 Common - Type IV leader peptidase family protein CPF_2571 119 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110799461 Common - hypothetical protein CPF_0107 14 None None None 110800304 Pathogen - hypothetical protein CPF_0996 1 None None None 110801043 Common spoIVA stage IV sporulation protein A CPF_2006 15 COG0536 Obg, Predicted GTPase General function prediction only 110799781 Common - MutS domain protein CPF_0305 196 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110799920 Common - haloacid dehalogenase, IB family protein CPF_1375 27 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110800026 Common - myo-inositol catabolism protein IolC CPF_0082 169 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110798733 Common - hypothetical protein CPF_2612 47 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 110801041 Common - hypothetical protein CPF_1045 5 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 110799027 Pathogen - hypothetical protein CPF_1418 1 None None None 110800037 Common nth endonuclease III CPF_1525 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 110799895 Pathogen - hypothetical protein CPF_1007 1 None None None 110799042 Common - sortase family protein CPF_0772 20 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110799730 Common - putative mutator mutT protein CPF_1031 162 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110799084 Common - lipoprotein, BMP family CPF_1516 105 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110799115 Common - hydrolase, NUDIX family CPF_0662 10 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110799145 Common - hypothetical protein CPF_1820 1 None None None 110800698 Common maf Maf-like protein CPF_2400 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 110800253 Pathogen - hypothetical protein CPF_1626 1 None None None 110799177 Common pyrD dihydroorotate dehydrogenase 1B CPF_1382 235 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 110801133 Common - transcriptional regulator, LacI family CPF_1547 127 COG1609 PurR, Transcriptional regulators Transcription 110798982 Common - glutamate:gamma aminobutyrate antiporter family protein CPF_2317 62 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110799475 Common - sensor histidine kinase CPF_0837 97 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110799020 Common - DNA-cytosine methyltransferase CPF_0139 129 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 110799278 Common - putative comE operon protein 1 CPF_2375 116 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 110800044 Common - rubredoxin/rubrerythrin CPF_2955 22 COG1592 COG1592, Rubrerythrin Energy production and conversion 110799855 Common - putative cell division protein FtsL CPF_2798 4 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 110798638 Common - glycosyl hydrolase, family 8 CPF_2247 6 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 110798847 Common - hypothetical protein CPF_1719 13 None None None 110801189 Common - hypothetical protein CPF_2741 9 None None None 110800598 Common - transcriptional regulator, MerR family CPF_0455 100 COG0789 SoxR, Predicted transcriptional regulators Transcription 110799669 Pathogen - hypothetical protein CPF_0941 1 None None None 110800843 Common - sensor histidine kinase CPF_0554 118 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 110801058 Common - MiaB-like tRNA modifying enzyme YliG, TIGR01125 CPF_1929 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110800948 Pathogen - hypothetical protein CPF_0659 1 None None None 110800540 Common - pseudouridine synthase, RluA family CPF_2377 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110800125 Pathogen - hypothetical protein CPF_0932 1 None None None 110799398 Common - putative co-chaperone GrpE CPF_0240 11 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 110800416 Pathogen - hypothetical protein CPF_1632 1 None None None 110801051 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CPF_1722 23 COG0756 Dut, dUTPase Nucleotide transport and metabolism 110800764 Common - hypothetical protein CPF_1870 1 None None None 110799969 Common - methyltransferase, UbiE/COQ5 family CPF_0168 179 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110799654 Common potA spermidine/putrescine ABC transporter, ATP-binding protein CPF_2223 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110798929 Common cbiG cobalamin biosynthesis protein CbiG CPF_1429 82 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 110799826 Common - DedA family protein CPF_0884 158 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110798709 Common prkA serine protein kinase CPF_1541 72 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 110800471 Common - hypothetical protein CPF_0624 6 None None None 110798976 Common - hypothetical protein CPF_1861 2 None None None 110799571 Common luxS S-ribosylhomocysteinase CPF_0171 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 110800726 Common - hypothetical protein CPF_1898 1 None None None 110799612 Common - nucleoside transporter, NupC family CPF_1492 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 110799258 Common - glycosyl hydrolase, family 2 CPF_0826 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 110800778 Common pcp pyrrolidone-carboxylate peptidase CPF_1678 51 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 110800913 Common - putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase CPF_2165 142 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 110801429 Common pepF oligoendopeptidase F CPF_1706 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 110799953 Common - hypothetical protein CPF_1598 8 None None None 110801025 Common - sulfatase CPF_2501 70 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110799544 Common - acetyltransferase, GNAT family CPF_0869 6 COG0456 RimI, Acetyltransferases General function prediction only 110799741 Common - hypothetical protein CPF_1256 14 None None None 110800936 Common - hypothetical protein CPF_0101 3 COG5523 COG5523, Predicted integral membrane protein Function unknown 110799100 Pathogen - hypothetical protein CPF_0814 1 None None None 110800001 Common - hypothetical protein CPF_0983 6 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110800515 Common - cell division protein FtsQ CPF_2112 18 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 110800645 Pathogen - hypothetical protein CPF_1230 1 None None None 110798813 Pathogen - putative lipoprotein CPF_1805 1 None None None 110799791 Common dnaA chromosomal replication initiation protein CPF_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 110799910 Common - hypothetical protein CPF_0013 5 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 110801034 Pathogen - hypothetical protein CPF_1438 1 None None None 110801361 Common - hypothetical protein CPF_0632 2 None None None 110800994 Common - putative methyltransferase CPF_1983 215 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 110799060 Common - major facilitator family transporter CPF_2556 91 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110799621 Common - regulatory protein SpoVG CPF_2814 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 110800074 Pathogen - hypothetical protein CPF_0668 1 None None None 110798627 Common - membrane protein, DedA family CPF_1865 9 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110801431 Common - peptidase, T4 family CPF_1675 53 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110800734 Common - hypothetical protein CPF_0945 2 None None None 110799747 Common - transcriptional regulator, RpiR family CPF_1338 97 COG1737 RpiR, Transcriptional regulators Transcription 110801063 Pathogen - hypothetical protein CPF_1470 1 None None None 110800988 Common narA nitrate reductase, catalytic subunit CPF_2052 188 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110799919 Common - hypothetical protein CPF_0152 29 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 110801004 Common - putative phage structural protein CPF_1574 188 COG4926 PblB, Phage-related protein Function unknown 110799660 Common - hypothetical protein CPF_2594 2 None None None 110798720 Common - putative diguanylate cyclase CPF_1264 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110800234 Common feoB ferrous iron transport protein B CPF_1125 197 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 110800067 Pathogen - hypothetical protein CPF_0924 1 None None None 110800741 Pathogen - hypothetical protein CPF_0931 1 None None None 110800334 Common - putative thiosulfate sulfurtransferase CPF_1308 113 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110800476 Common - hypothetical protein CPF_1514 12 None None None 110799866 Common - xanthine/uracil permease family protein CPF_2004 136 COG2252 COG2252, Permeases General function prediction only 110800100 Common - phosphoglucomutase/phosphomannomutase family protein CPF_2127 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110800824 Common - PTS system, IIA component CPF_2965 67 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 110800317 Common uvrA excinuclease ABC, A subunit CPF_0337 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 110800979 Common - hypothetical protein CPF_1537 1 None None None 110801263 Common - hypothetical protein CPF_0437 1 None None None 110801272 Common - putative transcriptional regulator CPF_0738 64 COG1733 COG1733, Predicted transcriptional regulators Transcription 110799833 Common clpP ATP-dependent Clp protease proteolytic subunit CPF_1647 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110798915 Common - radical SAM protein, TIGR01212 family CPF_2882 90 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 110800782 Common - hypothetical protein CPF_1292 2 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 110800140 Common - DNA replication protein DnaC CPF_2940 36 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 110798727 Pathogen - hypothetical protein CPF_1302 1 None None None 110801403 Common - hypothetical protein CPF_2407 78 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 110801438 Common - spore maturation protein B CPF_2856 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 110800981 Common - hypothetical protein CPF_2366 4 None None None 110800052 Common - putative lipoprotein CPF_2099 2 None None None 110799716 Pathogen - putative type IV pilin CPF_2567 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 110798779 Pathogen - hypothetical protein CPF_0200 1 None None None 110798771 Common - acetyltransferase, GNAT family CPF_1183 19 COG0456 RimI, Acetyltransferases General function prediction only 110798840 Common - conserved hypothetical protein TIGR00044 CPF_2108 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 110799623 Common nagE PTS system, N-acetylglucosamine-specific IIBC component CPF_0071 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110800708 Common - aldose 1-epimerase CPF_1551 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 110798780 Common - aspartate kinase I CPF_1932 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 110801283 Common - glutathione peroxidase CPF_1198 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 110799294 Common - hypothetical protein CPF_0824 6 COG5522 COG5522, Predicted integral membrane protein Function unknown 110798674 Common ogt methylated-DNA-[protein]-cysteine S-methyltransferase CPF_0326 207 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 110798695 Common - DNA-binding response regulator CPF_1056 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110800779 Common - RNA pseudouridine synthase family protein CPF_2613 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110799441 Pathogen - hypothetical protein CPF_1866 1 None None None 110800801 Common - putative transcriptional regulator CPF_0280 61 COG1316 LytR, Transcriptional regulator Transcription 110798892 Pathogen - hypothetical protein CPF_0201 1 None None None 110801243 Common - hypothetical protein CPF_0805 2 None None None 110800709 Common - GTP pyrophosphokinase-like protein CPF_1858 27 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 110800935 Common - hypothetical protein CPF_1034 29 COG3339 COG3339, Uncharacterized conserved protein Function unknown 110799662 Common - putative lipoprotein CPF_2510 3 None None None 110800518 Common - transcriptional regulator, MarR family CPF_1323 41 COG1846 MarR, Transcriptional regulators Transcription 110801364 Common - transcriptional regulator, Crp/Fnr family CPF_1250 175 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110801291 Common - sensor histidine kinase CPF_0511 106 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 110800102 Common - hypothetical protein CPF_2921 9 COG1950 COG1950, Predicted membrane protein Function unknown 110800556 Common - response regulator CPF_0888 223 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 110798565 Pathogen - hypothetical protein CPF_0925 1 None None None 110801358 Common - putative phage minor capsid protein CPF_0951 3 None None None 110800366 Common nusA transcription elongation factor NusA CPF_1943 227 COG0195 NusA, Transcription elongation factor Transcription 110801155 Common - polysaccharide deacetylase family protein CPF_2167 72 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110799987 Common radA DNA repair protein RadA CPF_2743 221 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 110799130 Common glpK glycerol kinase CPF_2876 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 110800103 Common - hypothetical protein CPF_2208 46 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 110800242 Common - putative lysophospholipase CPF_1188 72 COG2267 PldB, Lysophospholipase Lipid metabolism 110798913 Common argR arginine repressor CPF_2070 71 COG1438 ArgR, Arginine repressor Transcription 110799600 Common - DNA-binding response regulator CPF_2504 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110799473 Common - hypothetical protein CPF_1742 4 COG0730 COG0730, Predicted permeases General function prediction only 110799128 Common - ABC transporter, permease protein CPF_1829 134 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 110801036 Pathogen - hypothetical protein CPF_2550 1 None None None 110799801 Common - hypothetical protein CPF_1496 19 None None None 110800591 Common - ABC transporter, ATP-binding protein CPF_2868 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110800392 Common - phosphoglycerate mutase family protein CPF_0078 169 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110799401 Common - feoA family protein CPF_1126 5 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110799530 Common - site-specific recombinase, phage integrase family CPF_1590 87 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110799786 Common - putative ferrichrome ABC transporter, permease protein FhuG CPF_0809 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110800433 Common mreD rod shape-determining protein MreD CPF_2396 5 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110800636 Common - nucleoside recognition domain protein CPF_2910 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 110799360 Common - hypothetical protein CPF_2733 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 110800136 Pathogen - hypothetical protein CPF_0021 1 None None None 110800187 Common - transcriptional regulator, GntR family CPF_2285 78 COG1725 COG1725, Predicted transcriptional regulators Transcription 110800788 Common moeA molybdenum cofactor biosynthesis protein MoeA CPF_2048 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110800622 Common cobK cobalt-precorrin-6x reductase CPF_1427 45 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 110801094 Common - hypothetical protein CPF_0716 192 COG0628 PerM, Predicted permease General function prediction only 110798718 Common - pyridine nucleotide-disulphide oxidoreductase family protein CPF_0728 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 110800021 Common - SCP-like extracellular family protein CPF_0827 67 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 110799448 Common dapF diaminopimelate epimerase CPF_2100 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 110800623 Pathogen - putative lipoprotein CPF_1876 1 None None None 110799314 Common - iron-sulfur cluster-binding protein CPF_2351 15 COG0716 FldA, Flavodoxins Energy production and conversion 110799682 Common - S4 domain protein CPF_0003 41 COG2501 COG2501, Uncharacterized conserved protein Function unknown 110800996 Common - glycosyl hydrolase, family 25 CPF_1568 48 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110800893 Common - putative ethanolamine utilization protein CPF_0899 5 None None None 110800499 Pathogen - hypothetical protein CPF_1571 1 None None None 110798573 Common feoB ferrous iron transport protein B CPF_1913 189 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 110801078 Common cphA cyanophycin synthetase CPF_2477 202 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110799738 Common - hypothetical protein CPF_2402 127 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110799877 Common - conserved hypothetical protein TIGR02336 CPF_0553 4 None None None 110800345 Common fucK L-fuculokinase CPF_1049 113 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 110798707 Common - endo-beta-N-acetylglucosaminidase CPF_0285 30 COG4724 COG4724, Endo-beta-N-acetylglucosaminidase D Carbohydrate transport and metabolism 110800956 Common rpsS 30S ribosomal protein S19 CPF_2710 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 110799880 Common - acyl-ACP thioesterase family protein CPF_2953 22 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 110801378 Pathogen - hypothetical protein CPF_1864 1 None None None 110800564 Common - putative sensor histidine kinase CPF_0863 177 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 110799014 Common - TPR domain protein CPF_2126 21 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110798600 Common - hypothetical protein CPF_1405 32 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 110800534 Common cobI cobalt-precorrin-2 C(20)-methyltransferase CPF_1431 152 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 110799450 Common - putative lipoprotein CPF_1767 1 None None None 110800429 Common - hypothetical protein CPF_1337 28 None None None 110800670 Common potB spermidine/putrescine ABC transporter, permease protein PotB CPF_2224 160 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110799093 Common - ethanolamine ammonia-lyase small subunit CPF_0892 53 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 110800286 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CPF_1360 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 110800404 Common - GGDEF/EAL domain protein CPF_0238 164 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110799229 Common cax calcium/proton exchanger CPF_1624 86 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 110798900 Common - glutaredoxin-like protein, YruB-family CPF_2747 67 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110800420 Common fusA elongation factor G CPF_2717 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110798696 Common - stage II sporulation protein P CPF_2297 15 None None None 110799810 Common - hypothetical protein CPF_1674 12 COG4684 COG4684, Predicted membrane protein Function unknown 110800438 Common - CutC family protein CPF_0254 57 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 110799482 Common - polysaccharide deacetylase family protein CPF_0372 112 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110798975 Common - hypothetical protein CPF_1116 6 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 110801311 Common - amino acid/peptide transporter CPF_0523 79 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 110798755 Common ung uracil-DNA glycosylase CPF_0258 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 110799427 Common aspD aspartate aminotransferase CPF_1258 75 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110799299 Common - pyridine nucleotide-disulphide oxidoreductase CPF_2663 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110801339 Common - toxin secretion/phage lysis holin CPF_0971 14 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 110798934 Common - putative accessory gene regulator protein B CPF_1813 2 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 110799689 Common - [2Fe-2S]-binding domain protein CPF_2866 4 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110801303 Common - spore germination protein CPF_0630 11 None None None 110798943 Common - hypothetical protein CPF_1612 4 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 110800537 Common - hypothetical protein CPF_0763 2 None None None 110799192 Common - glutamate decarboxylase CPF_2315 66 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 110799632 Pathogen - hypothetical protein CPF_0018 1 None None None 110798869 Common - hypothetical protein CPF_0776 26 COG2461 COG2461, Uncharacterized conserved protein Function unknown 110800806 Common - putative membrane-associated zinc metalloprotease CPF_2608 167 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 110798596 Common lonB ATP-dependent protease LonB CPF_1645 244 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110801056 Common - hypothetical protein CPF_1627 1 None None None 110799006 Common - ABC transporter, ATP-binding protein CPF_1478 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110800459 Common - hypothetical protein CPF_0102 6 COG5523 COG5523, Predicted integral membrane protein Function unknown 110800867 Common - hypothetical protein CPF_2168 4 None None None 110801159 Common - hypothetical protein CPF_0531 8 COG3326 COG3326, Predicted membrane protein Function unknown 110800668 Common - putative phage terminase, large subunit CPF_1587 45 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 110800374 Common rpmF 50S ribosomal protein L32 CPF_1975 64 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 110800589 Common - CBS domain protein CPF_2408 10 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 110801269 Common thiI thiamine biosynthesis/tRNA modification protein ThiI CPF_1666 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 110799039 Common - nucleotidyl transferase family protein CPF_2607 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 110798850 Common moaA molybdenum cofactor biosynthesis protein A CPF_2045 207 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110799759 Common - glycerophosphoryl diester phosphodiesterase family protein CPF_2131 166 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110799972 Common - lysM domain protein CPF_2479 16 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 110799901 Pathogen - putative lipoprotein CPF_1812 1 None None None 110801164 Common - hypothetical protein CPF_2415 88 COG4717 COG4717, Uncharacterized conserved protein Function unknown 110801335 Common rumA 23S rRNA (uracil-5-)-methyltransferase RumA CPF_2370 195 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 110801168 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC CPF_2311 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110798769 Common - hypothetical protein CPF_1968 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 110798636 Common - heme/steroid binding domain protein CPF_2822 6 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 110800855 Common - degV family protein CPF_2832 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110799861 Common mgtE magnesium transporter CPF_1450 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 110799594 Pathogen - hypothetical protein CPF_1091 1 None None None 110801196 Common - hypothetical protein CPF_2562 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 110800082 Common - capsular polysaccharide biosynthesis protein CPF_0914 190 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800711 Common dedA dedA protein CPF_1159 153 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110799435 Common - competence damage-inducible protein A CPF_0130 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 110798609 Pathogen - hypothetical protein CPF_0963 1 None None None 110798745 Common - PTS system, N-acetylglucosamine-specific IIBC component CPF_1070 54 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110798883 Common cotJB spore coat protein CotJB CPF_1067 9 None None None 110799639 Common rpsF 30S ribosomal protein S6 CPF_2978 205 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 110800657 Pathogen - hypothetical protein CPF_0936 1 None None None 110800904 Common - hypothetical protein CPF_1260 8 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 110799121 Common - DNA-binding response regulator CPF_1139 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110799908 Common sdhB L-serine dehydratase, iron-sulfur-dependent, beta subunit CPF_1245 97 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110800061 Pathogen - hypothetical protein CPF_0920 1 None None None 110799281 Common - Na+/H+ antiporter family protein CPF_2617 59 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 110799705 Common - pyrophosphatase PpaX CPF_2232 209 COG0546 Gph, Predicted phosphatases General function prediction only 110799725 Common - hypothetical protein CPF_2890 1 None None None 110800580 Common - hypothetical protein CPF_0311 4 None None None 110800871 Pathogen - hypothetical protein CPF_1138 1 None None None 110800817 Common - putative lipoprotein CPF_2502 4 None None None 110799533 Common - coenzyme B12-dependent glycerol dehydratase, small subunit CPF_1175 13 COG4910 PduE, Propanediol dehydratase, small subunit Secondary metabolites biosynthesis, transport, and catabolism 110799694 Common infB translation initiation factor IF-2 CPF_1940 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 110799941 Common rho transcription termination factor Rho CPF_2471 205 COG1158 Rho, Transcription termination factor Transcription 110799403 Common - sodium:glactoside symporter family protein CPF_0733 78 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 110800791 Common dhaG glycerol dehydratase reactivation factor, small subunit CPF_1177 2 None None None 110798666 Common - hypothetical protein CPF_0315 8 COG5523 COG5523, Predicted integral membrane protein Function unknown 110801127 Common - primase-like protein CPF_2841 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 110798653 Common - transcriptional regulator, CarD family CPF_0252 2 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 110799292 Common trxB thioredoxin-disulfide reductase CPF_2750 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110799555 Common - PemK family protein CPF_0291 63 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 110799979 Common - conserved hypothetical protein TIGR00278 CPF_2995 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 110800224 Common - HRDC domain protein CPF_0665 63 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 110799491 Pathogen - hypothetical protein CPF_1253 1 None None None 110800450 Common - glycosyl hydrolase, family 31/fibronectin type III domain protein CPF_1301 84 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 110801318 Common - putative permease CPF_1201 176 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110799424 Common - signal peptidase I CPF_0312 169 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110798622 Common - putative monogalactosyldiacylglycerol synthase CPF_0710 36 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110800765 Common - type III restriction-modification system, Res subunit CPF_0362 51 COG3587 COG3587, Restriction endonuclease Defense mechanisms 110800360 Common rpsK 30S ribosomal protein S11 CPF_2687 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 110800503 Common - hypothetical protein CPF_0752 156 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 110798877 Common - hypothetical protein CPF_0933 1 None None None 110798825 Common - Orn/Lys/Arg decarboxylase CPF_0528 91 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 110800522 Common - hypothetical protein CPF_1634 1 None None None 110798764 Common - hypothetical protein CPF_0418 13 COG4640 COG4640, Predicted membrane protein Function unknown 110798849 Common - hypothetical protein CPF_1141 12 None None None 110801385 Common coaE dephospho-CoA kinase CPF_2249 186 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 110800922 Common - haloacid dehalogenase, IA family protein CPF_0269 177 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 110798777 Common - RNA polymerase sigma-70 factor, ECF family CPF_1092 102 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110800020 Common cmk cytidylate kinase CPF_1340 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 110800066 Common yabP sporulation protein YabP CPF_2800 13 None None None 110800878 Common - hypothetical protein CPF_1240 7 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 110800910 Common - peptidyl-prolyl cis-trans isomerase family protein CPF_0262 156 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 110799279 Pathogen - hypothetical protein CPF_0959 1 None None None 110798968 Common - ATPase domain protein CPF_1497 93 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 110801266 Common pyrE orotate phosphoribosyltransferase CPF_1381 155 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 110799142 Common - aminotransferase, class V CPF_0060 167 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 110799838 Common trmB tRNA (guanine-N(7))-methyltransferase CPF_0427 131 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 110799359 Common cysE serine O-acetyltransferase CPF_1528 214 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 110799608 Common - purine nucleoside phosphorylase CPF_0386 142 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110799733 Common - myo-inositol 2-dehydrogenase CPF_0085 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110800750 Common - putative type II restriction endonuclease CPF_1016 8 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 110799546 Common - FmtC domain protein CPF_1845 56 COG2898 COG2898, Uncharacterized conserved protein Function unknown 110800164 Common - putative ABC transporter permease protein CPF_0303 12 None None None 110800142 Pathogen - hypothetical protein CPF_2017 1 None None None 110801006 Common - ABC transporter, permease protein CPF_0557 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110799831 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase CPF_0397 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 110799011 Pathogen - hypothetical protein CPF_1128 1 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 110798842 Common - putative glucuronyl hydrolase CPF_0400 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 110798703 Common - endonuclease/exonuclease/phosphatase family protein CPF_1311 26 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 110800751 Common atpD F0F1 ATP synthase subunit beta CPF_2452 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 110799659 Common - hypothetical protein CPF_1842 27 COG2966 COG2966, Uncharacterized conserved protein Function unknown 110800982 Common - subtilase family protein CPF_2937 55 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110800687 Common - choloylglycine hydrolase CPF_0705 53 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 110798772 Common - degV family protein CPF_0301 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110800773 Common pyk pyruvate kinase CPF_2404 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110801274 Pathogen - hypothetical protein CPF_1395 1 None None None 110801401 Pathogen - hypothetical protein CPF_1121 1 None None None 110799922 Common spoVD stage V sporulation protein D CPF_2134 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110799072 Common - hypothetical protein CPF_2736 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 110798743 Common - cold shock protein CPF_1452 178 COG1278 CspC, Cold shock proteins Transcription 110799744 Common - ABC transporter, permease/ATP-binding protein CPF_0506 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110801423 Common pstC phosphate ABC transporter, permease protein PstC CPF_0619 231 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110800760 Common - transcriptional regulator, LacI family CPF_1879 125 COG1609 PurR, Transcriptional regulators Transcription 110799025 Common ksgA dimethyladenosine transferase CPF_2840 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 110801066 Pathogen - hypothetical protein CPF_1909 1 None None None 110799517 Common eutD phosphotransacetylase CPF_1978 163 COG0280 Pta, Phosphotransacetylase Energy production and conversion 110800510 Common - putative glycerol uptake facilitator protein CPF_1170 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 110800483 Pathogen - hypothetical protein CPF_0519 1 None None None 110799918 Common spoVB stage V sporulation protein B CPF_2804 63 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110799864 Common - transcriptional regulator, LacI family CPF_2817 131 COG1609 PurR, Transcriptional regulators Transcription 110799139 Common - glutamine amidotransferase, CobB/CobQ family CPF_1393 56 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 110800997 Common - bacterial extracellular solute-binding protein CPF_1077 13 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110800124 Common - hypothetical protein CPF_0109 2 None None None 110799016 Common - MATE efflux family protein CPF_1483 133 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110800460 Common - 6-phosphofructokinase CPF_1718 158 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110799960 Common - hypothetical protein CPF_0235 1 None None None 110799377 Common - ATP-dependent DNA helicase, UvrD/REP family CPF_1872 81 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 110799849 Common - diacylglycerol kinase/PAP2 family protein CPF_2274 104 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 110800413 Common - hypothetical protein CPF_0806 75 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110799376 Common - membrane protein, YbiE/YbiF family CPF_1617 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 110799947 Common - DNA-binding response regulator CPF_0459 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110801018 Common - cyclic nucleotide-binding protein CPF_0388 14 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110798615 Common - sugar-binding domain protein CPF_1512 60 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 110798986 Common tenA transcriptional activator TenA CPF_2870 76 COG0819 TenA, Putative transcription activator Transcription 110800050 Common rfbA glucose-1-phosphate thymidylyltransferase CPF_0597 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110800127 Common - acetyltransferase, GNAT family CPF_0862 2 COG0456 RimI, Acetyltransferases General function prediction only 110800990 Common - glycosyl hydrolase, family 31 CPF_2648 80 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 110800664 Common - hypothetical protein CPF_0218 7 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 110800373 Common - transcriptional regulator, ArsR family/dinitrogenase iron-molybdenum cofactor family protein CPF_1286 55 COG1433 COG1433, Uncharacterized conserved protein Function unknown 110799967 Common - DNA-binding response regulator CPF_2811 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110800439 Common eutP ethanolamine utilization protein, EutP CPF_0887 19 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 110799666 Common - nicotinate phosphoribosyltransferase CPF_1417 107 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 110799610 Common - hypothetical protein CPF_2591 1 None None None 110799794 Pathogen - hypothetical protein CPF_1024 1 None None None 110800962 Common - hypothetical protein CPF_0289 1 None None None 110801132 Common - hypothetical protein CPF_2158 53 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 110800577 Common - hypothetical protein CPF_1095 1 None None None 110800966 Common - hypothetical protein CPF_1026 1 None None None 110800220 Pathogen - hypothetical protein CPF_0822 1 None None None 110800545 Common - putatve dicarboxylate transporter CPF_1242 38 COG1288 COG1288, Predicted membrane protein Function unknown 110799757 Common - membrane protein, DedA family CPF_1744 155 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110800693 Common garR 2-hydroxy-3-oxopropionate reductase CPF_0381 188 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 110799370 Common - aminopeptidase, M42 family CPF_1252 77 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 110800251 Common - putative adenylate cyclase CPF_1559 9 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 110800087 Common - hypothetical protein CPF_0812 2 None None None 110800517 Pathogen - hypothetical protein CPF_0957 1 None None None 110800919 Common sipW signal peptidase I CPF_0493 21 None None None 110800724 Common hemC porphobilinogen deaminase CPF_1688 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 110799062 Common - oligopeptide transporter, OPT family CPF_1485 41 COG1297 COG1297, Predicted membrane protein Function unknown 110799652 Common dcm DNA-cytosine methyltransferase CPF_1018 117 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 110799940 Common - pantothenate kinase CPF_2784 131 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 110799619 Pathogen - hypothetical protein CPF_2871 1 None None None 110799917 Common - tetratricopeptide repeat protein CPF_2176 23 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110801011 Common - iron(III) ABC transporter, permease protein CPF_1425 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110800107 Common - PTS system, IIB component CPF_1716 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 110800329 Common - hypothetical protein CPF_2401 1 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 110798858 Common - cell wall anchor domain protein CPF_0210 2 COG5386 COG5386, Cell surface protein Cell envelope biogenesis, outer membrane 110799628 Pathogen - hypothetical protein CPF_1729 1 None None None 110800319 Common - HAD hydrolase, IIB family CPF_1519 145 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110799776 Common - oxidoreductase, pyridine nucleotide-disulphide family CPF_2499 193 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110801215 Common - sortase B CPF_0492 5 COG4509 COG4509, Uncharacterized protein conserved in bacteria Function unknown 110800229 Common kdpC K+-transporting ATPase, C subunit CPF_1212 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 110801350 Common - hypothetical protein CPF_0825 4 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110799058 Common - hypothetical protein CPF_2539 1 None None None 110801258 Common - ABC transporter, ATP-binding protein CPF_0841 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110800180 Pathogen - hypothetical protein CPF_1309 1 None None None 110801158 Common - metallo-beta-lactamase family protein CPF_2932 70 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 110800188 Common - hypothetical protein CPF_2561 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110800310 Common - hypothetical protein CPF_0839 5 None None None 110799927 Common rpmD 50S ribosomal protein L30 CPF_2696 133 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 110799251 Common - oxidoreductase, short chain dehydrogenase/reductase family CPF_2905 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110800508 Common - hypothetical protein CPF_1232 55 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 110799286 Common - ABC transporter, ATP-binding protein CPF_1831 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 110799582 Common - putative transcriptional regulator CPF_0696 94 COG1733 COG1733, Predicted transcriptional regulators Transcription 110799171 Common - capsular polysaccharide biosynthesis protein CPF_0910 189 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110800957 Common - electron transport complex, RnfABCDGE type, D subunit CPF_1664 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 110801087 Common - hypothetical protein CPF_2336 4 COG3247 HdeD, Uncharacterized conserved protein Function unknown 110800259 Common proA gamma-glutamyl phosphate reductase CPF_2903 201 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 110799714 Common - hypothetical protein CPF_1556 2 None None None 110799395 Pathogen - preprotein translocase, YajC subunit CPF_0405 2 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 110800566 Common - hypothetical protein CPF_1441 6 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 110800883 Common - DHH subfamily 1 protein CPF_1938 83 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 110800232 Common - conserved hypothetical protein TIGR00247 CPF_2026 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 110799248 Common - capsular polysaccharide biosynthesis protein CPF_0465 222 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110800785 Common brnQ branched-chain amino acid transport system II carrier protein CPF_0050 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 110801117 Common - hesB family protein CPF_0654 1 None None None 110800035 Common - site-specific recombinase, resolvase family CPF_2604 70 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110801319 Common thrS threonyl-tRNA synthetase CPF_2631 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110798611 Common - ROK family protein CPF_2334 129 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110799798 Common feoA ferrous iron transport protein A CPF_1127 58 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110799096 Common - aspartate aminotransferase CPF_0325 212 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110799233 Common rpoB DNA-directed RNA polymerase subunit beta CPF_2722 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 110798832 Common - hypothetical protein CPF_2111 22 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 110801398 Common - ABC transporter, ATP-binding protein CPF_1721 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110798954 Common - cytidine/deoxycytidylate deaminase family protein CPF_0037 217 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 110799086 Common - subtilase family protein CPF_2369 11 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110800961 Common ftsH ATP-dependent metalloprotease FtsH CPF_2786 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 110800498 Common - PDZ domain protein CPF_2809 218 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110800554 Common truA tRNA pseudouridine synthase A CPF_1248 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 110798663 Pathogen - hypothetical protein CPF_0100 1 None None None 110800003 Common fmt methionyl-tRNA formyltransferase CPF_1005 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 110800383 Common - transposase, IS605 OrfB family CPF_1008 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110799673 Common nagH hyaluronidase CPF_0184 16 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110800443 Common - amidinotransferase family protein CPF_0329 50 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 110799812 Common - drug resistance transporter, EmrB/QacA subfamily CPF_1448 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110800041 Common groES co-chaperonin GroES CPF_2574 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 110800207 Common tyrS tyrosyl-tRNA synthetase CPF_0633 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110798589 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CPF_0215 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110799170 Common - putative fibronectin-binding protein CPF_0735 7 None None None 110798861 Pathogen bofA sigma-K factor processing regulatory protein BofA CPF_0056 1 None None None 110798890 Common - D-alanyl-D-alanine carboxypeptidase family protein CPF_1631 40 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110799999 Common - oxidoreductase, 2-nitropropane dioxygenase family CPF_1249 122 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 110800096 Common - putative DNA polymerase III, epsilon subunit CPF_1920 8 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 110798991 Common - hypothetical protein CPF_0320 119 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110798793 Common - hypothetical protein CPF_1041 1 None None None 110801205 Common - cell cycle protein, FtsW/RodA/SpoVE family CPF_2391 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110800595 Common - putative glycerophosphoryl diester phosphodiesterase CPF_0424 181 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110799535 Common - YeeE/YedE family protein CPF_0729 56 None None None 110799331 Common clpP clp protease CPF_1931 44 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110799992 Common - aldehyde dehydrogenase family protein CPF_2610 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110801181 Common - major facilitator family protein CPF_0425 56 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110799033 Pathogen - hypothetical protein CPF_0358 1 None None None 110800570 Common - putative glycogen debranching enzyme, archaeal type CPF_2645 42 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 110800897 Common arcA arginine deiminase CPF_0161 60 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 110800409 Common lysA diaminopimelate decarboxylase CPF_0576 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 110799219 Common - tyrosine-protein kinase protein CPF_0919 155 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110800458 Common - hypothetical protein CPF_1836 13 COG4720 COG4720, Predicted membrane protein Function unknown 110799117 Common - hypothetical protein CPF_0250 44 COG4748 COG4748, Uncharacterized conserved protein Function unknown 110801171 Common - heme oxygenase CPF_0205 24 COG5398 COG5398, Heme oxygenase Inorganic ion transport and metabolism 110801222 Common - polysaccharide lyase, family 8 CPF_0394 15 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110800091 Common aspC aspartyl-tRNA synthetase CPF_0770 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110799601 Common - hypothetical protein CPF_0232 7 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 110799389 Common - cell wall binding repeat protein/mannosyl-glycoprotein endo-beta-N-acetylglucosamidase domain CPF_0605 10 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110800305 Common ytaF putative sporulation protein YtaF CPF_2330 12 COG1971 COG1971, Predicted membrane protein Function unknown 110799749 Common crcB crcB protein CPF_1284 150 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 110799958 Common - phosphoglycerate mutase family protein CPF_1293 4 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110798922 Common fba fructose-1,6-bisphosphate aldolase, class II CPF_1557 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 110798752 Common - hypothetical protein CPF_2839 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110801306 Common rpsD 30S ribosomal protein S4 CPF_2686 220 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 110801367 Common lepB signal peptidase I CPF_0432 167 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110799504 Common - hypothetical protein CPF_1014 9 None None None 110799803 Common - hypothetical protein CPF_0447 4 None None None 110800322 Common - putative mannosyltransferase CPF_2487 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800341 Common - GatB/Yqey domain protein CPF_2279 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 110800748 Common - mechanosensitive ion channel family protein CPF_2980 195 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110799306 Common - glycosyl transferase, group 4 family protein CPF_1886 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 110798884 Common - perfringolysin O CPF_0156 7 None None None 110798594 Common - Mg chelatase-like protein CPF_1958 203 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 110799241 Common mutS DNA mismatch repair protein CPF_1358 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110799154 Common - TPR domain protein CPF_0650 6 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110799104 Common - hypothetical protein CPF_1807 41 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110800682 Common - hypothetical protein CPF_0568 199 COG0628 PerM, Predicted permease General function prediction only 110799274 Common - NlpC/P60 family protein CPF_1562 103 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 110799817 Pathogen - hypothetical protein CPF_1599 1 None None None 110799906 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CPF_0214 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110798978 Common - DedA family protein CPF_1745 156 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110800475 Common rplT 50S ribosomal protein L20 CPF_2144 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 110798767 Common - putative lipoprotein CPF_0722 15 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 110801093 Common - phage protein, HK97 gp10 family CPF_1581 2 None None None 110799558 Pathogen - hypothetical protein CPF_1371 1 None None None 110798875 Common - DNA-binding response regulator CPF_0836 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110798606 Common def peptide deformylase CPF_0754 185 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 110800211 Pathogen - hypothetical protein CPF_1104 1 None None None 110799446 Common - alcohol dehydrogenase, short-chain family CPF_2331 26 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 110799466 Common - putative transcriptional regulator CPF_0612 62 COG1316 LytR, Transcriptional regulator Transcription 110800900 Common - hypothetical protein CPF_0966 3 None None None 110801414 Common rpmH 50S ribosomal protein L34 CPF_2997 12 None None None 110800811 Common - putative tetracycline resistance protein CPF_1233 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110798734 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase CPF_2007 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110800456 Common recO DNA repair protein RecO CPF_2271 25 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 110799635 Common - von Willebrand factor type A/Cna B-type domain protein CPF_0774 11 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110799405 Common - hypothetical protein CPF_2974 17 COG4241 COG4241, Predicted membrane protein Function unknown 110801433 Common - KID repeat family protein CPF_0969 13 None None None 110799343 Common nadE NAD synthetase CPF_1314 188 COG0171 NadE, NAD synthase Coenzyme metabolism 110801144 Common - putative lipoprotein CPF_2836 1 None None None 110801148 Common - radical SAM enzyme, Cfr family CPF_1993 195 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 110800049 Common rplB 50S ribosomal protein L2 CPF_2711 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 110801408 Pathogen - hypothetical protein CPF_0142 1 None None None 110801362 Common - pseudouridine synthase, RluA family CPF_2104 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110801190 Common - hypothetical protein CPF_2578 2 None None None 110800680 Common - potassium/proton antiporter CPF_2920 175 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 110800840 Common lacZ beta-galactosidase CPF_1221 74 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 110800712 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein CPF_2557 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 110799638 Pathogen - heavy metal binding protein CPF_2406 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 110798742 Common - flavodoxin family protein CPF_0793 100 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 110800816 Common - cobalt ABC transporter, ATP-binding protein CPF_2682 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110800853 Common fusA elongation factor G CPF_0074 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110799704 Common - hypothetical protein CPF_2642 2 None None None 110799937 Common - type IV pilus biogenesis protein PilN CPF_2564 2 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 110800895 Common rpoN RNA polymerase factor sigma-54 CPF_1513 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 110799312 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein CPF_2206 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110799422 Common - bacterial sugar transferase family protein CPF_0912 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110800216 Common scrK fructokinase CPF_0734 175 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110800427 Common - tetratricopeptide repeat protein CPF_2234 11 None None None 110798886 Common - hypothetical protein CPF_1658 13 None None None 110800930 Common - hypothetical protein CPF_2357 1 None None None 110801333 Common - hypothetical protein CPF_2030 19 None None None 110800112 Common - translocator protein, LysE family CPF_2982 39 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110798563 Common - transcriptional regulator, MarR family CPF_1106 90 COG1846 MarR, Transcriptional regulators Transcription 110800808 Common - hypothetical protein CPF_1266 2 None None None 110801047 Common - hypothetical protein CPF_1814 2 None None None 110798698 Pathogen - hypothetical protein CPF_0864 1 None None None 110800536 Common - transcriptional regulator, AsnC family CPF_1906 123 COG1522 Lrp, Transcriptional regulators Transcription 110799625 Common - ethanolamine utilization protein CPF_0898 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 110798644 Common - F5/8 type C domain protein CPF_1489 12 None None None 110800757 Common pheS phenylalanyl-tRNA synthetase subunit alpha CPF_2140 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 110800691 Common - bacterial type II secretion system protein F CPF_2569 143 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 110800641 Pathogen - hypothetical protein CPF_1394 1 None None None 110800109 Common ppcA phosphoenolpyruvate carboxylase CPF_1350 17 COG1892 COG1892, Uncharacterized protein conserved in archaea Function unknown 110798656 Common - hypothetical protein CPF_0134 1 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 110800266 Common - glycosyl hydrolase, family 31 CPF_0843 75 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 110800654 Common - hypothetical protein CPF_0173 37 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 110798985 Common hrcA heat-inducible transcription repressor CPF_2292 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 110800861 Common - pyridine nucleotide-disulphide oxidoreductase family protein CPF_1145 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110799338 Common - hypothetical protein CPF_0113 9 COG4640 COG4640, Predicted membrane protein Function unknown 110801344 Common - putative lipid kinase CPF_1535 102 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 110798901 Common - hypothetical protein CPF_1793 46 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 110798634 Common - hypothetical protein CPF_0577 6 None None None 110800407 Pathogen - hypothetical protein CPF_0804 1 None None None 110800131 Common fhs formate--tetrahydrofolate ligase CPF_2785 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 110799566 Pathogen - hypothetical protein CPF_1443 1 None None None 110801411 Common - hypothetical protein CPF_1740 1 None None None 110798863 Common - NAD(+)/NADH kinase CPF_2071 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 110801317 Common - hydroxylamine reductase CPF_2909 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 110799004 Common - hypothetical protein CPF_1097 1 None None None 110798640 Pathogen - hypothetical protein CPF_0128 1 None None None 110800732 Common - DNA-bindng response regulator, AraC family CPF_1172 226 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110800356 Common - hypothetical protein CPF_2138 13 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110798820 Common - hypothetical protein CPF_1607 3 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110799297 Common addA ATP-dependent nuclease, subunit A CPF_0025 229 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 110801064 Common - hypothetical protein CPF_1707 2 None None None 110800047 Common - oxidoreductase, short chain dehydrogenase/reductase family CPF_0723 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110800909 Common - ABC transporter, permease/ATP-binding protein CPF_0366 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110799201 Common - putative iron-sulfur cluster-binding protein CPF_1527 135 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 110798786 Common modA molybdate ABC transporter, molybdate-binding protein CPF_2342 168 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 110800827 Common spoIIIAF stage III sporulation protein AF CPF_2082 4 None None None 110801337 Common thyX FAD-dependent thymidylate synthase CPF_2735 81 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 110799876 Common - xanthine/uracil permease family protein CPF_1827 135 COG2252 COG2252, Permeases General function prediction only 110799677 Common - SPFH domain protein/band 7 family protein CPF_1316 221 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110800621 Pathogen - hypothetical protein CPF_0125 1 None None None 110799723 Common cobM precorrin-4 C11-methyltransferase CPF_1430 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 110800176 Common sbp small basic protein CPF_2110 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 110798917 Pathogen - hypothetical protein CPF_1003 1 None None None 110799247 Common - putative molybdenum cofactor biosynthesis protein CPF_2046 74 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110801085 Pathogen - hypothetical protein CPF_1363 1 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 110799263 Common rfbB dTDP-glucose 4,6-dehydratase CPF_0482 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 110799863 Common - putative glutamine synthetase CPF_2894 222 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 110799680 Common - putative lipoprotein CPF_1278 1 None None None 110799252 Common - transcriptional regulator, MarR family CPF_0505 93 COG1846 MarR, Transcriptional regulators Transcription 110799488 Common bioD dithiobiotin synthetase CPF_1794 163 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 110801395 Common cbiT precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit CPF_1432 69 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 110800278 Common - sodium:alanine symporter family protein CPF_2219 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 110800655 Common spoVR stage V sporulation protein R CPF_1539 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 110800984 Common rumA 23S rRNA (uracil-5-)-methyltransferase RumA CPF_0357 201 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 110798607 Common argS arginyl-tRNA synthetase CPF_1915 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110800138 Pathogen - hypothetical protein CPF_1638 1 None None None 110800838 Common - hypothetical protein CPF_2137 21 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110799208 Common lon ATP-dependent protease La CPF_1644 209 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 110800381 Common - DHH domain protein CPF_2195 158 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110799783 Pathogen - hypothetical protein CPF_1462 1 None None None 110800942 Common - hypothetical protein CPF_0742 2 None None None 110800186 Common - comF protein CPF_2431 139 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 110799806 Common - hypothetical protein CPF_0041 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 110800548 Common - glycosyl transferase, group 2 family protein CPF_0715 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110799886 Common - hypothetical protein CPF_0500 2 None None None 110800299 Common - glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein CPF_0538 179 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 110801233 Common - putative nuclease SbcCD, D subunit CPF_0206 116 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 110801381 Common - C4-dicarboxylate transporter family protein CPF_0126 32 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 110800582 Common - small, acid-soluble spore protein CPF_1676 13 None None None 110801297 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein CPF_2207 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110799260 Common fabD malonyl CoA-acyl carrier protein transacylase CPF_1325 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 110800512 Common ylbJ sporulation integral membrane protein YlbJ CPF_1981 15 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 110800505 Common ruvA Holliday junction DNA helicase motor protein CPF_2204 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 110799382 Common - hypothetical protein CPF_0953 1 None None None 110798827 Common - putative PTS system, N-acetylglucosamine-specific IIA component CPF_0070 61 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 110798579 Common asrB anaerobic sulfite reductase subunit B CPF_1692 149 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110800763 Pathogen - hypothetical protein CPF_2593 1 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 110799321 Common - metallo-beta-lactamase family protein CPF_0284 93 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110800010 Pathogen - hypothetical protein CPF_1107 1 None None None 110800362 Pathogen - phage protein, QlrG family CPF_1583 1 None None None 110799687 Pathogen - hypothetical protein CPF_0380 1 None None None 110799502 Common truA tRNA pseudouridine synthase A CPF_2680 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 110800519 Common - hypothetical protein CPF_0775 9 None None None 110801256 Common rpmE 50S ribosomal protein L31 CPF_2469 188 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 110798899 Common dhaF glycerol dehydratase reactivation factor, large subunit CPF_1176 12 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 110800611 Common - ferredoxin--NADP(+) reductase subunit alpha CPF_1464 89 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110800803 Common - transcriptional regulator, AraC family CPF_0209 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110801327 Common - sulfate permease, SulP family CPF_1731 166 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 110798762 Pathogen - hypothetical protein CPF_0954 2 None None None 110798655 Common typA GTP-binding protein TypA CPF_2027 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 110798664 Common - putative translaldolase CPF_0684 171 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 110800797 Common - hypothetical protein CPF_1636 2 None None None 110800265 Common - DNA-binding protein CPF_1604 25 COG1396 HipB, Predicted transcriptional regulators Transcription 110798959 Common - hypothetical protein CPF_1734 6 None None None 110800284 Common - putative sensory box-containing diguanylate cyclase CPF_1164 187 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 110799509 Common - putative sulfite/nitrite reductase CPF_0443 155 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110799572 Common - sulfatase family protein CPF_0221 90 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110798676 Common - hypothetical protein CPF_0972 1 None None None 110799044 Common hlyIII hemolysin III CPF_2171 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 110799894 Common - capsule chain length determinant protein CPF_0464 31 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 110799194 Pathogen - hypothetical protein CPF_0099 1 None None None 110798683 Common - sigma-54 dependent transcriptional regulator/sensory box protein CPF_2667 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 110800394 Common glpF glycerol uptake facilitator protein CPF_2878 131 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 110801323 Common - hypothetical protein CPF_0744 17 COG1309 AcrR, Transcriptional regulator Transcription 110800662 Common ftsA cell division protein FtsA CPF_2019 168 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 110800608 Pathogen - hypothetical protein CPF_0935 1 None None None 110800271 Common dapB dihydrodipicolinate reductase CPF_2162 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 110799889 Common - cell wall binding repeat domain protein CPF_0490 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110799883 Common map methionine aminopeptidase, type I CPF_1635 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 110799410 Common - multidrug resistance protein CPF_1028 133 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110800937 Common - flavodoxin family protein CPF_0535 63 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 110801284 Common - sensor histidine kinase CPF_1171 112 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 110801075 Common - acetyltransferase, GNAT family CPF_0711 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 110799133 Common prsA ribose-phosphate pyrophosphokinase CPF_2812 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110801245 Pathogen - hypothetical protein CPF_0023 1 None None None 110799661 Common - cell envelope-related transcriptional attenuator domain protein CPF_2170 62 COG1316 LytR, Transcriptional regulator Transcription 110800849 Common - TrkA domain protein CPF_1615 12 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 110800244 Common rpsQ 30S ribosomal protein S17 CPF_2705 225 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 110799752 Common - hypothetical protein CPF_1134 2 None None None 110798715 Common - hypothetical protein CPF_2922 8 None None None 110800974 Common - ABC transporter, ATP-binding protein CPF_0829 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110799872 Common - sulfatase domain protein CPF_0585 60 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110799828 Common - copper-translocating P-type ATPase CPF_0534 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110798795 Common rplA 50S ribosomal protein L1 CPF_2725 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 110800700 Common - sulfatase family protein CPF_0584 69 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 110799471 Common - sodium:neurotransmitter symporter family protein CPF_1621 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 110800017 Common - hypothetical protein CPF_1806 2 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 110800706 Common - putative cobalt ABC transporter, permease protein CPF_1834 63 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110800152 Common - HD domain protein CPF_2379 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 110800022 Common - PAP2 family protein CPF_0795 59 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 110799978 Common - hypothetical protein CPF_1143 14 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 110798873 Common - putative RNA-binding protein CPF_2381 82 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 110800462 Common - transcriptional regulator, AraC family CPF_1698 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110801315 Common - hypothetical protein CPF_2485 1 None None None 110800357 Common - hypothetical protein CPF_2148 3 None None None 110799046 Common - alanine racemase family protein CPF_1317 166 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 110798580 Common - hypothetical protein CPF_0522 202 COG0628 PerM, Predicted permease General function prediction only 110799559 Common rnz ribonuclease Z CPF_1613 107 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 110798750 Pathogen - hypothetical protein CPF_0984 1 None None None 110799603 Common proB gamma-glutamyl kinase CPF_2904 195 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 110799890 Common - hypothetical protein CPF_2930 2 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 110799393 Common cbiM cobalt transport protein CbiM CPF_0185 58 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 110800917 Common - rhodanese-like domain protein CPF_2864 117 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110801410 Common - MATE efflux family protein CPF_1081 98 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110800829 Common fmt methionyl-tRNA formyltransferase CPF_1996 221 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 110801137 Common hup DNA-binding protein HU CPF_2802 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 110799796 Common pstS phosphate ABC transporter, phosphate-binding protein CPF_0617 172 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 110800129 Common - putative iron transporter CPF_0211 2 COG5386 COG5386, Cell surface protein Cell envelope biogenesis, outer membrane 110800572 Common - putative L-ascorbate 6-phosphate lactonase CPF_0643 30 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110800331 Common - putative phage major capsid protein CPF_0956 4 None None None 110800964 Common - hypothetical protein CPF_1419 1 None None None 110798988 Common - putative acyl-CoA thioesterase CPF_2498 60 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110800543 Pathogen - hypothetical protein CPF_1572 3 COG1511 COG1511, Predicted membrane protein Function unknown 110800968 Common - hypothetical protein CPF_1637 1 None None None 110800079 Common - hypothetical protein CPF_1873 2 None None None 110801352 Pathogen - hypothetical protein CPF_0725 1 None None None 110800767 Common - hypothetical protein CPF_0108 13 COG4086 COG4086, Predicted secreted protein Function unknown 110799290 Common - transcriptional regulator, AraC family CPF_0765 128 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110798692 Common mglA galactose/methyl galaxtoside transporter ATP-binding protein CPF_1549 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110801130 Common rplK 50S ribosomal protein L11 CPF_2726 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 110800028 Common - putative arylsulfatase regulator CPF_0616 107 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 110800257 Common - potassium uptake protein, TrkH family CPF_2143 119 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110799173 Common - F5/8 type C domain protein CPF_0652 16 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 110800579 Common miaB tRNA-i(6)A37 thiotransferase enzyme MiaB CPF_1349 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110799196 Pathogen - hypothetical protein CPF_0120 1 None None None 110799407 Common - hypothetical protein CPF_1524 115 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110798865 Common addB ATP-dependent nuclease, subunit B CPF_0024 35 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 110800873 Common - putative ferrichrome ABC transporter, permease protein FhuB CPF_0808 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110800019 Pathogen - hypothetical protein CPF_1027 1 None None None 110801121 Common - 3-hydroxybutyryl-CoA dehydratase CPF_0090 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110798816 Common - hypothetical protein CPF_0923 6 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110800722 Common - electron transfer flavoprotein, alpha subunit/FixB family protein CPF_2582 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 110801061 Common - hypothetical protein CPF_2252 1 None None None 110799149 Common - glycosyl transferase, group 2 family protein CPF_0602 73 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110799617 Common pfl formate acetyltransferase CPF_1356 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 110799372 Common pyrH uridylate kinase CPF_1952 241 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 110799664 Common - glycosyl hydrolase, family 20 CPF_1614 62 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 110799302 Common - amino acid ABC transporter, ATP-binding protein CPF_1533 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110800070 Common - bacterial transferase hexpeptide repeat protein CPF_1903 211 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 110801032 Common entD mannosyl-glycoprotein endo-beta-N-acetylglucosamidase domain protein, possible enterotoxin CPF_1439 18 COG4193 LytD, Beta- N-acetylglucosaminidase Carbohydrate transport and metabolism 110800928 Common rnfG electron transport complex, RnfABCDGE type, G subunit CPF_1318 69 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 110799357 Common - rubrerythrin family protein CPF_0368 6 COG1633 COG1633, Uncharacterized conserved protein Function unknown 110798966 Common - hypothetical protein CPF_1986 35 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 110800820 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 CPF_2128 165 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 110799981 Common - phosphorylase family protein CPF_0978 22 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 110801413 Common rpsD 30S ribosomal protein S4 CPF_2668 241 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 110800068 Common - metallo-beta-lactamase family protein CPF_0783 89 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110801268 Common - FliB family protein CPF_0797 6 None None None 110798705 Common - hypothetical protein CPF_1965 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 110800689 Common - hypothetical protein CPF_1481 7 None None None 110801008 Common - hypothetical protein CPF_2614 1 None None None 110798770 Common nrdD anaerobic ribonucleoside triphosphate reductase CPF_2830 110 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 110800144 Common rplQ 50S ribosomal protein L17 CPF_2684 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 110798671 Common rplW 50S ribosomal protein L23 CPF_2712 222 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 110800593 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CPF_1946 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 110801435 Common cspA serine protease A CPF_2888 11 None None None 110798911 Pathogen - hypothetical protein CPF_1844 1 None None None 110801115 Common - flavodoxin CPF_0625 26 COG0716 FldA, Flavodoxins Energy production and conversion 110799140 Common spoVB stage V sporulation protein B CPF_1900 50 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110801039 Common - hypothetical protein CPF_1216 6 None None None 110799905 Common cdsA phosphatidate cytidylyltransferase CPF_1949 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 110799931 Pathogen - hypothetical protein CPF_0135 1 None None None 110800999 Common - ATP synthase-like protein CPF_1896 15 None None None 110801276 Common - UBA/TS-N domain protein CPF_2270 3 None None None 110799938 Common - transcriptional regulator, TetR family CPF_0364 14 COG1309 AcrR, Transcriptional regulator Transcription 110801179 Common sodF Mn/Fe superoxide dismutase CPF_1446 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 110799225 Common - hypothetical protein CPF_0433 16 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 110798830 Pathogen - hypothetical protein CPF_0747 1 None None None 110799254 Common - subtilase family protein CPF_2368 12 None None None 110798775 Common - putative oligo-1,6-glucosidase CPF_0421 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110799074 Common - PAP2 family protein CPF_1280 108 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 110798844 Common - ethanolamine utilization protein EutH CPF_0902 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 110800012 Common - Orn/Lys/Arg decarboxylase CPF_2763 82 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 110800198 Common tig trigger factor CPF_1648 212 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 110800153 Common ptsG PTS system, glucose-specific IIBC component CPF_2412 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110799994 Common map methionine aminopeptidase, type I CPF_2692 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 110800106 Common rpe ribulose-phosphate 3-epimerase CPF_1989 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 110799428 Pathogen - hypothetical protein CPF_2257 1 None None None 110800481 Common lepA GTP-binding protein LepA CPF_2295 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 110798933 Common - hypothetical protein CPF_0155 10 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 110799152 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CPF_0689 233 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 110801418 Pathogen - hypothetical protein CPF_2094 1 None None None 110800043 Pathogen - hypothetical protein CPF_0038 1 None None None 110799496 Common - transcriptional regulator, AraC family CPF_1047 138 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110800247 Common - transcriptional regulator, PadR family CPF_1333 2 COG1695 COG1695, Predicted transcriptional regulators Transcription 110799956 Pathogen - hypothetical protein CPF_0114 1 None None None 110800869 Common thiH thiamine biosynthesis protein ThiH CPF_1853 58 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 110800491 Common - putative surface protein CPF_0147 11 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110799961 Common - cell wall surface anchor family protein CPF_0771 12 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110799598 Pathogen - prepilin-type N-terminal cleavage/methylation domain protein CPF_2560 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 110799515 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CPF_2449 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 110800684 Common - bacterial extracellular solute-binding proteins, family 5 CPF_2538 123 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110798924 Common - putative iron ABC transporter, ATP-binding protein CPF_0442 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110801230 Common - hypothetical protein CPF_0454 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110800268 Common apt adenine phosphoribosyltransferase CPF_2194 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110799578 Common - hypothetical protein CPF_0040 10 None None None 110798906 Common glyS glycyl-tRNA synthetase CPF_2779 87 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 110801207 Common - hypothetical protein CPF_0787 13 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 110801105 Common xth exodeoxyribonuclease III CPF_1377 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 110799183 Common - hypothetical protein CPF_0195 82 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 110799983 Pathogen - hypothetical protein CPF_1578 1 None None None 110800746 Common axe1 acetylxylan esterase CPF_1848 19 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 110799356 Pathogen - hypothetical protein CPF_0663 1 None None None 110798801 Common - transcriptional regulator, PadR family CPF_2833 24 COG1695 COG1695, Predicted transcriptional regulators Transcription 110799008 Pathogen - hypothetical protein CPF_0429 1 None None None 110800738 Common - hypothetical protein CPF_0202 16 None None None 110799729 Common mfd transcription-repair coupling factor CPF_2807 239 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 110800350 Common - hypothetical protein CPF_0058 1 None None None 110799210 Common - putative transcriptional activator tipA CPF_0331 115 COG0789 SoxR, Predicted transcriptional regulators Transcription 110799161 Common - transcriptional regulator, LacI family CPF_0420 129 COG1609 PurR, Transcriptional regulators Transcription 110799468 Common - PTS system, lactose/cellobiose-specific IIB component CPF_0502 33 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 110801289 Pathogen - hypothetical protein CPF_1071 1 None None None 110801151 Common - ABC transporter, ATP-binding protein CPF_1792 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110800293 Common dcm DNA-cytosine methyltransferase CPF_1017 113 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 110801304 Pathogen - hypothetical protein CPF_2908 1 None None None 110799217 Common - glycosyl transferase, group 1 family protein CPF_0265 51 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110799915 Common aroE shikimate 5-dehydrogenase CPF_0693 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110799589 Common - ATP:guanido phosphotransferase CPF_2752 26 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 110799506 Common - transcriptional regulator, MarR family CPF_0789 36 COG1846 MarR, Transcriptional regulators Transcription 110798822 Common - hypothetical protein CPF_2597 4 None None None 110799367 Pathogen - hypothetical protein CPF_1404 1 None None None 110801013 Common - stage III sporulation protein AE CPF_2083 15 None None None 110800390 Pathogen - hypothetical protein CPF_1023 1 None None None 110800227 Common kptA RNA 2'-phosphotransferase CPF_0145 43 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 110799764 Common trmE tRNA modification GTPase TrmE CPF_2992 230 COG0486 ThdF, Predicted GTPase General function prediction only 110798856 Common ddl D-alanine--D-alanine ligase CPF_1522 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 110799739 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CPF_1227 142 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110800648 Common - transcriptional regulator, Fur family CPF_2029 202 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110799836 Common - tRNA 2-selenouridine synthase CPF_2327 65 COG2603 COG2603, Predicted ATPase General function prediction only 110800567 Common - hypothetical protein CPF_1365 1 None None None 110798930 Common - metallo-beta-lactamase family protein CPF_1750 122 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 110799774 Common - putative N-acetylmuramoyl-L-alanine amidase CPF_0111 104 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110800323 Common - putative cation transporter CPF_1262 117 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 110799591 Common pyrB aspartate carbamoyltransferase catalytic subunit CPF_1387 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 110798628 Common minD septum site-determining protein MinD CPF_2393 147 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 110798765 Common mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase CPF_0063 103 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 110798726 Common ribA riboflavin biosynthesis protein RibA CPF_0548 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 110800959 Common - putative aminopeptidase 1 CPF_1263 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 110798808 Common mnaA UDP-N-acetylglucosamine 2-epimerase CPF_2461 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 110800182 Common - hydrolase, NUDIX family CPF_1062 8 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110798997 Common - hydrolase, alpha/beta fold family CPF_0434 106 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110800941 Common - putative glucokinase CPF_0076 178 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110801017 Common spoVS stage V sporulation protein S CPF_1925 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 110798575 Common - transcriptional regulator, MarR family CPF_1029 25 COG1846 MarR, Transcriptional regulators Transcription 110799929 Common - hypothetical protein CPF_0416 4 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 110798854 Common scpB segregation and condensation protein B CPF_2059 157 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 110800147 Common - CAAX amino terminal protease family protein CPF_0988 53 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 110800890 Common - hypothetical protein CPF_2873 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 110799235 Pathogen - hypothetical protein CPF_1224 1 None None None 110801239 Common - ExsB family protein CPF_1247 172 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110800560 Common - ATP-dependent protease CPF_2971 242 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110800885 Common - putative hyaluronidase CPF_1442 23 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 110800178 Common - acetyltransferase, GNAT family CPF_0905 12 None None None 110798700 Common - RNA methyltransferase, RsmE family CPF_2283 203 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 110801001 Pathogen - hypothetical protein CPF_0955 2 None None None 110800312 Common - hypothetical protein CPF_0352 4 None None None 110800678 Common iscS cysteine desulfurase CPF_2039 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 110800836 Common - hypothetical protein CPF_2263 1 None None None 110800375 Common arcC carbamate kinase CPF_0164 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 110799433 Common - signal peptidase I CPF_0578 171 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110800038 Common - putative phage minor capsid protein CPF_0952 11 None None None 110799379 Common sigG sporulation sigma factor SigG CPF_2014 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110798829 Common - transcriptional regulator, MarR family/choline/ethanolamine kinase CPF_0608 29 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110801073 Common - DNA-binding protein CPF_1053 11 COG1476 COG1476, Predicted transcriptional regulators Transcription 110799098 Common - McrB domain protein CPF_0992 46 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 110799580 Pathogen - hypothetical protein CPF_0934 1 None None None 110799081 Common potD spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein CPF_2226 137 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110800308 Common galE UDP-glucose 4-epimerase CPF_0486 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 110800805 Common - putative pullulanase CPF_1839 156 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 110800055 Common dnaB replicative DNA helicase CPF_1597 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 110800674 Common - hypothetical protein CPF_0603 14 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 110801396 Common - PIN/TRAM domain protein CPF_2740 45 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 110800209 Common - hypothetical protein CPF_2214 1 None None None 110799769 Common - putative ribonuclease HI CPF_1703 15 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 110801370 Common uppS undecaprenyl diphosphate synthase CPF_1950 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110798965 Common - MATE efflux family protein CPF_0835 176 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110801026 Common tsf elongation factor Ts CPF_1953 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 110799110 Common - sensor histidine kinase CPF_0225 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110800695 Common - putative manganese-dependent inorganic pyrophosphatase CPF_2312 55 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 110801200 Pathogen - putative lipoprotein CPF_1090 1 None None None 110799018 Common - chromate transport protein CPF_2509 114 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 110798592 Common - glycosyl transferase, group 1 CPF_0477 8 None None None 110799788 Common - sensor histidine kinase CPF_0889 87 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 110799364 Common ribE riboflavin synthase subunit alpha CPF_0547 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 110799328 Pathogen - hypothetical protein CPF_0255 1 None None None 110798971 Common cloSI alpha-clostripain CPF_0840 11 None None None 110799675 Common - glycosyl hydrolase, family 25 CPF_0973 49 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110798658 Common - hypothetical protein CPF_1367 1 None None None 110800400 Common - putative zinc ABC transporter, permease protein CPF_1710 193 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 110798646 Common cax calcium/proton exchanger CPF_1817 125 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 110800851 Common - hypothetical protein CPF_0428 20 COG3538 COG3538, Uncharacterized conserved protein Function unknown 110800847 Common secY preprotein translocase subunit SecY CPF_2694 230 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 110800583 Common spoVE stage V sporulation protein E CPF_2113 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110799438 Common - RNA chaperone Hfq CPF_1361 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 110798760 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase CPF_1936 211 COG0196 RibF, FAD synthase Coenzyme metabolism 110799457 Pathogen - hypothetical protein CPF_0877 1 None None None 110800348 Common - hypothetical protein CPF_1738 45 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110800652 Common - stage III sporulation protein AC CPF_2085 15 None None None 110798903 Common - putative ATP:cob(I)alamin adenosyltransferase CPF_1178 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 110799069 Pathogen - hypothetical protein CPF_1642 1 None None None 110800110 Common - oxidoreductase, FAD-binding CPF_0411 159 COG0579 COG0579, Predicted dehydrogenase General function prediction only 110800425 Pathogen - hypothetical protein CPF_0448 1 None None None 110799647 Common - DNA-binding protein CPF_1032 57 COG1476 COG1476, Predicted transcriptional regulators Transcription 110799002 Common - hypothetical protein CPF_2287 2 None None None 110799568 Common - DHH family protein CPF_2973 89 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 110800057 Common - hypothetical protein CPF_2009 30 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 110799220 Common ytxC putative sporulation protein YtxC CPF_2147 15 None None None 110801119 Common - DNA-binding response regulator CPF_0623 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110800196 Common - putative amidohydrolase CPF_2239 71 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 110801346 Common - ABC transporter, permease protein CPF_2338 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110799035 Common - glycosyl hydrolase, family 25 CPF_0369 46 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110799431 Common prsA peptidylprolyl isomerase CPF_2806 108 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 110798642 Common - putative myo-inositol catabolism protein IolB CPF_0083 34 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 110800464 Pathogen - hypothetical protein CPF_1486 1 None None None 110798687 Common glmS D-fructose-6-phosphate amidotransferase CPF_2636 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 110799998 Common - cysteine synthase family protein CPF_0170 228 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 110799564 Common selD selenide, water dikinase CPF_2374 136 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 110799965 Common - acetyltransferase, GNAT family CPF_1379 45 COG0456 RimI, Acetyltransferases General function prediction only 110801142 Common - putative pilus biogenesis protein CPF_2098 212 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 110800710 Common dhaT 1,3-propanediol dehydrogenase CPF_1180 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110800977 Common - glutamate:gamma-aminobutyrate antiporter family protein CPF_1507 55 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110799945 Common - voltage-gated chloride channel family protein CPF_1662 152 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110801369 Common - mannose-6-phosphate isomerase domain protein CPF_2592 152 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 110801342 Common topB DNA topoisomerase III CPF_1760 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110799856 Common - hypothetical protein CPF_0409 8 COG4269 COG4269, Predicted membrane protein Function unknown 110799874 Common - hypothetical protein CPF_0713 3 None None None 110799721 Common - hypothetical protein CPF_0044 25 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110798661 Common - hypothetical protein CPF_0011 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 110800240 Pathogen - hypothetical protein CPF_0313 1 None None None 110799540 Pathogen - hypothetical protein CPF_1901 1 None None None 110798888 Common - peptidase, M23/M37 family CPF_2938 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110798927 Common - glutaminase CPF_0571 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 110800094 Common - hypothetical protein CPF_2634 23 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110801146 Common - amino acid permease family protein CPF_1181 103 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110799143 Common - transporter, auxin efflux carrier family CPF_0509 30 COG0679 COG0679, Predicted permeases General function prediction only 110798839 Common - hypothetical protein CPF_1765 10 None None None 110799819 Common - [Fe] hydrogenase CPF_1076 85 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110801286 Common - putative esterase CPF_0172 135 COG0657 Aes, Esterase/lipase Lipid metabolism 110800628 Pathogen - hypothetical protein CPF_2669 1 None None None 110799168 Common - hypothetical protein CPF_0236 1 COG2510 COG2510, Predicted membrane protein Function unknown 110798568 Common - PTS system, mannose/fructose/sorbose family, IIC component CPF_0402 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 110800875 Pathogen - hypothetical protein CPF_0755 1 None None None 110799706 Common cysS cysteinyl-tRNA synthetase CPF_2737 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110799690 Common - hypothetical protein CPF_0335 36 COG1950 COG1950, Predicted membrane protein Function unknown 110800249 Common - putative metal-dependent hydrolase, membrane-bound CPF_1203 12 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 110801112 Common - hypothetical protein CPF_1801 10 None None None 110798784 Common - oligopeptide/dipeptide ABC transporter, ATP-binding protein CPF_2551 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 110800813 Common - putative CoA-substrate-specific enzyme activase CPF_1406 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 110799552 Common - hypothetical protein CPF_0149 5 None None None 110799064 Common - putative thiamin biosynthesis lipoprotein ApbE CPF_2363 130 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 110799486 Common - hypothetical protein CPF_1084 3 None None None 110801053 Common ligA NAD-dependent DNA ligase LigA CPF_2541 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 110801232 Pathogen - hypothetical protein CPF_1601 1 None None None 110799336 Common rpsP 30S ribosomal protein S16 CPF_1966 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 110800818 Common - hypothetical protein CPF_0062 46 COG4198 COG4198, Uncharacterized conserved protein Function unknown 110799051 Common - oligoendopeptidase, M3 family CPF_2632 77 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 110798846 Pathogen - putative lipoprotein CPF_1823 1 None None None 110799111 Common - cation efflux family protein CPF_1144 187 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110800454 Common - GGDEF/HD domain protein CPF_1811 178 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 110798797 Common cphB cyanophycinase CPF_2478 35 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 110800282 Pathogen - hypothetical protein CPF_1641 1 None None None 110798739 Common - hypothetical protein CPF_0194 14 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 110799199 Common - hypothetical protein CPF_0796 5 None None None 110799605 Common - hypothetical protein CPF_1976 51 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 110798740 Pathogen - hypothetical protein CPF_0701 1 None None None 110798749 Pathogen - hypothetical protein CPF_0419 1 None None None 110800714 Pathogen - putative lipoprotein CPF_0514 1 None None None 110800230 Pathogen - putative lipoprotein CPF_1610 1 None None None 110799341 Common - BadF/BadG/BcrA/BcrD ATPase family protein CPF_2149 53 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 110800065 Common nusG transcription antitermination protein NusG CPF_2727 215 COG0250 NusG, Transcription antiterminator Transcription 110799270 Common - phage major capsid protein, HK97 family CPF_1584 8 None None None 110800610 Common - putative oxidoreductase CPF_0412 19 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110801262 Pathogen - hypothetical protein CPF_1589 1 None None None 110801192 Common prfC peptide chain release factor 3 CPF_0592 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 110798672 Common - putative cob(I)alamin adenosyltransferase CPF_2164 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 110799537 Common dacF D-alanyl-D-alanine carboxypeptidase CPF_2061 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110801240 Common plsX fatty acid/phospholipid synthesis protein CPF_1974 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 110801218 Common - transcriptional regulator, LacI family CPF_0407 125 COG1609 PurR, Transcriptional regulators Transcription 110800761 Pathogen - hypothetical protein CPF_0651 1 None None None 110800739 Pathogen - putative lipoprotein CPF_1351 1 None None None 110799701 Common deaD ATP-dependent RNA helicase DeaD CPF_0855 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110799814 Common - putative nicotinamide mononucleotide transporter PnuC CPF_0387 46 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 110799528 Common - amidohydrolase family protein CPF_1002 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110801406 Common - transcriptional regulator, GntR family CPF_0445 128 COG1725 COG1725, Predicted transcriptional regulators Transcription 110798940 Common rpsT 30S ribosomal protein S20 CPF_2299 61 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 110801045 Common - hypothetical protein CPF_1558 6 None None None 110798871 Pathogen - hypothetical protein CPF_2540 1 None None None 110798897 Common - putative lipoprotein CPF_0244 9 None None None 110800072 Common - hypothetical protein CPF_2981 2 None None None 110801161 Common splB spore photoproduct lyase CPF_0720 24 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 110800939 Common ptb phosphate butyryltransferase CPF_2657 131 COG0280 Pta, Phosphotransacetylase Energy production and conversion 110800633 Common - DNA polymerase III subunit delta' CPF_2759 190 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 110801325 Common - hypothetical protein CPF_0979 2 COG5234 CIN1, Beta-tubulin folding cofactor D Posttranslational modification, protein turnover, chaperones / Cytoskeleton 110799310 Common proS prolyl-tRNA synthetase CPF_2738 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110800755 Common purM phosphoribosylaminoimidazole synthetase CPF_0675 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 110799125 Common - putative ribosomal protein L11 methyltransferase CPF_2360 164 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 110799412 Pathogen - hypothetical protein CPF_0799 1 None None None 110801183 Common - phospholipase, patatin family CPF_1826 46 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 110799808 Pathogen - hypothetical protein CPF_0390 1 COG2433 COG2433, Uncharacterized conserved protein Function unknown 110799526 Common rpsJ 30S ribosomal protein S10 CPF_2715 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 110800118 Common - peptidase family protein CPF_2481 11 None None None 110800795 Pathogen - hypothetical protein CPF_1373 1 None None None 110799180 Common - cell wall surface anchor family protein CPF_0146 12 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 110801186 Common - oligopeptide/dipeptide ABC transporter, permease protein CPF_2553 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110800263 Common - metallo-beta-lactamase family protein CPF_1910 128 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 110800166 Common - hypothetical protein CPF_1846 3 COG2898 COG2898, Uncharacterized conserved protein Function unknown 110800214 Common - hypothetical protein CPF_1044 14 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 110799158 Common - acetyltransferase domain protein CPF_1378 2 COG0456 RimI, Acetyltransferases General function prediction only 110800338 Common - rrf2 family protein CPF_2040 179 COG1959 COG1959, Predicted transcriptional regulator Transcription 110800396 Common - hemolysin A CPF_2072 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 110799697 Common - oxidoreductase, short-chain dehydrogenase/reductase family CPF_2925 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110798632 Common - glycosyl transferase, group 1 family protein CPF_0268 50 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800703 Common - L-threonine-O-3-phosphate decarboxylase CPF_1295 237 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110798949 Common - putative polysaccharide transporter protein CPF_0474 34 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110799053 Common hemB delta-aminolevulinic acid dehydratase CPF_1686 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 110798688 Common - putative cadmium resistance transcriptional regulator CadC CPF_2588 191 COG0640 ArsR, Predicted transcriptional regulators Transcription 110798681 Common - sugar transporter, glycoside-pentoside-hexuronide (GPH):cation symporter family CPF_0764 83 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 110798678 Common - putative maltose/maltodextrin ABC transporter, maltose/maltodextrin-binding protein CPF_2652 86 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 110801247 Common aroQ 3-dehydroquinate dehydratase CPF_0695 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 110799419 Common - hypothetical protein CPF_0129 133 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110799288 Common rsgA ribosome-associated GTPase CPF_1990 163 COG1162 COG1162, Predicted GTPases General function prediction only 110799976 Common - hypothetical protein CPF_0413 19 COG2105 COG2105, Uncharacterized conserved protein Function unknown 110799304 Pathogen - hypothetical protein CPF_0852 1 None None None 110801425 Common - HAD hydrolase, IIB family CPF_0817 103 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110799750 Common - hypothetical protein CPF_1679 27 COG3817 COG3817, Predicted membrane protein Function unknown 110800715 Common hpt hypoxanthine phosphoribosyltransferase CPF_2216 144 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 110799089 Pathogen - putative type IV pilin CPF_2096 1 None None None 110800528 Common - hypothetical protein CPF_0393 66 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110799878 Common sdhA L-serine dehydratase, iron-sulfur-dependent, alpha subunit CPF_2960 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110800602 Common rimM 16S rRNA-processing protein CPF_1964 87 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 110799265 Common - hypothetical protein CPF_1908 6 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 110800388 Common - hypothetical protein CPF_1602 2 None None None 110799421 Common - hypothetical protein CPF_2220 1 None None None 110801083 Pathogen - hypothetical protein CPF_1914 1 None None None 110801357 Common - dihydrouridine synthase family protein CPF_1482 195 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110799498 Common - hypothetical protein CPF_2956 17 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 110800530 Common atpE ATP synthase F0, C subunit CPF_2457 3 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 110801393 Common spoIIAA anti-sigma F factor antagonist CPF_2307 69 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 110800863 Common - HAD-superfamily hydrolase, subfamily IIB CPF_0410 139 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110799123 Common - hypothetical protein CPF_2185 57 COG2966 COG2966, Uncharacterized conserved protein Function unknown 110799230 Common secA preprotein translocase subunit SecA CPF_2429 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 110799840 Common - ErfK/YbiS/YcfS/YnhG family protein CPF_0028 12 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110800272 Pathogen - hypothetical protein CPF_1033 3 None None None 110798919 Common - L-iditol 2-dehydrogenase CPF_0732 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110798992 Common - drug resistance transporter, EmrB/QacA family CPF_0096 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110800525 Pathogen - hypothetical protein CPF_2414 1 None None None 110799276 Common - hypothetical protein CPF_1616 15 None None None 110799318 Common - hypothetical protein CPF_0977 2 None None None 110800184 Common - amino acid ABC transporter, amino acid-binding protein CPF_0581 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110798811 Common - putative helicase CPF_0580 60 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 110799712 Common - sodium/solute symporter family protein CPF_0179 169 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 110801292 Common - thioesterase family protein CPF_1423 85 COG0824 FcbC, Predicted thioesterase General function prediction only 110801295 Common - ApbE family protein CPF_2491 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 110798732 Common - hypothetical protein CPF_0345 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 110799789 Common - polysaccharide deacetylase family protein CPF_1863 76 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110800367 Common fur-3 transcriptional regulator, Fur family CPF_1420 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110800953 Common - methenyltetrahydrofolate cyclohydrolase CPF_2123 33 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 110800159 Common - putative penicillin-binding protein CPF_2022 196 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110799262 Common drrA DNA-binding response regulator CPF_2674 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110801321 Common - hypothetical protein CPF_2935 6 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 110800601 Pathogen - hypothetical protein CPF_1781 1 None None None 110798818 Common - hypothetical protein CPF_2590 3 None None None 110800944 Common - hypothetical protein CPF_1299 53 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 110798714 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase CPF_0233 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 110799851 Common - sortase family protein CPF_0148 18 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110799627 Common - pyridine nucleotide-disulphide oxidoreductase CPF_1684 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110799207 Common - helicase, UvrD/REP/exonuclease family protein CPF_0426 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110801123 Common - hypothetical protein CPF_0516 61 COG1971 COG1971, Predicted membrane protein Function unknown 110798721 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type CPF_1819 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110799821 Common - hypothetical protein CPF_1875 3 None None None 110798577 Pathogen - hypothetical protein CPF_0389 1 None None None 110799825 Common tuf elongation factor Tu CPF_2730 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 110798799 Common nadB L-aspartate oxidase CPF_0383 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 110801299 Common prfB peptide chain release factor 2 CPF_2428 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 110801081 Common - D-alanyl-D-alanine carboxypeptidase family protein CPF_2231 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110801030 Pathogen - hypothetical protein CPF_2151 1 None None None 110798711 Common - transcriptional regulator, DeoR family CPF_0718 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110799685 Common nrdR transcriptional regulator NrdR CPF_2012 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 110800781 Common - radical SAM domain protein CPF_1971 86 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 110800562 Pathogen - hypothetical protein CPF_0786 1 None None None 110798616 Common fucA L-fuculose phosphate aldolase CPF_1051 162 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 110800504 Common - putative undecaprenyl diphosphate synthase CPF_1809 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110801377 Common - sulfite reductase, iron-sulfur subunit CPF_1693 32 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 110800472 Common - integral membrane protein TIGR01906 CPF_2575 9 COG4478 COG4478, Predicted membrane protein Function unknown 110800569 Pathogen - putative type IV pilin CPF_2093 1 None None None 110799523 Common accB acetyl-CoA carboxylase, biotin carboxyl carrier protein CPF_1328 189 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 110799852 Common - hypothetical protein CPF_2576 13 None None None 110801359 Common - putative nitrite/sulfite reductase CPF_1160 137 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110800676 Common pflA pyruvate formate-lyase activating enzyme CPF_1357 106 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110800834 Common - metallo-beta-lactamase family protein CPF_1168 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 110800624 Common - flavoredoxin CPF_1661 91 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110799315 Common - relA/spoT family protein CPF_1682 18 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 110801259 Common - hypothetical protein CPF_0993 29 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 110799399 Pathogen - hypothetical protein CPF_1118 1 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110801331 Common - rubredoxin/rubrerythrin CPF_0077 22 COG1592 COG1592, Rubrerythrin Energy production and conversion 110799267 Common folP dihydropteroate synthase CPF_1276 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 110800947 Common rbsD ribose ABC transporter, ribose-binding protein CPF_1883 43 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 110799439 Common - hypothetical protein CPF_1911 1 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 110799054 Common gltX glutamyl-tRNA synthetase CPF_1255 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110798667 Pathogen - hypothetical protein CPF_0458 3 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 110800637 Pathogen - hypothetical protein CPF_1279 1 None None None 110798972 Common add adenosine deaminase CPF_2829 117 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 110801290 Common spoVAD stage V sporulation protein AD CPF_2303 15 None None None 110799326 Common - putative transcriptional regulator IolR CPF_0079 117 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110801390 Common - ABC transporter, permease protein CPF_1830 124 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 110799900 Common atpA F0F1 ATP synthase subunit alpha CPF_2454 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 110800116 Common atpG F0F1 ATP synthase subunit gamma CPF_2453 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 110798572 Common - hypothetical protein CPF_2255 19 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 110799415 Common - hypothetical protein CPF_1137 36 COG1289 COG1289, Predicted membrane protein Function unknown 110799309 Common - hypothetical protein CPF_2362 5 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 110799494 Common ptsI phosphoenolpyruvate-protein phosphotransferase CPF_2666 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 110800950 Common - zinc transporter ZupT CPF_0717 79 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 110799127 Common acpP acyl carrier protein CPF_1973 98 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110799510 Pathogen - hypothetical protein CPF_0525 1 None None None 110801388 Common - hypothetical protein CPF_2899 3 None None None 110801188 Pathogen - hypothetical protein CPF_1905 1 None None None 110801185 Pathogen - hypothetical protein CPF_1344 1 None None None 110801242 Common - sucrose-6-phosphate dehydrogenase CPF_1783 51 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 110799352 Common yqfC sporulation protein YqfC CPF_2278 15 None None None 110799295 Common - putative lipoprotein CPF_2490 11 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 110799392 Common - RNA methyltransferase, TrmH family, group 2 CPF_1518 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 110800672 Common fnt formate/nitrite transporter CPF_1695 96 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 110799340 Common - dipeptidase PepV CPF_1421 156 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110798880 Common dapA dihydrodipicolinate synthase CPF_2161 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110799710 Common - putative methyltransferase CPF_2102 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 110801195 Common - hypothetical protein CPF_1206 1 None None None 110800716 Common - hypothetical protein CPF_2124 20 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110798724 Common - electron transfer flavoprotein, alpha subunit/FixB family protein CPF_0309 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 110800794 Common - hypothetical protein CPF_1797 11 COG4086 COG4086, Predicted secreted protein Function unknown 110800430 Common spoIIE stage II sporulation protein E CPF_2789 29 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 110799973 Common - conserved hypothetical protein TIGR00149 CPF_0551 130 COG0432 COG0432, Uncharacterized conserved protein Function unknown 110801174 Common - metallo-beta-lactamase family protein CPF_1573 18 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 110799539 Pathogen - hypothetical protein CPF_0658 1 None None None 110800167 Common - ferritin family protein CPF_1236 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 110800846 Pathogen - putative type IV pilin CPF_2568 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110800492 Common - hypothetical protein CPF_1457 32 COG0392 COG0392, Predicted integral membrane protein Function unknown 110798673 Common - hypothetical protein CPF_2892 1 None None None 110799409 Common dtd D-tyrosyl-tRNA deacylase CPF_2192 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 110801280 Common - cell wall binding repeat protein CPF_0607 28 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 110799185 Common - hypothetical protein CPF_1093 1 None None None 110799418 Common - DNA-binding response regulator, AraC family CPF_0555 215 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110799737 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CPF_2616 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 110799198 Common - hypothetical protein CPF_1754 17 COG0011 COG0011, Uncharacterized conserved protein Function unknown 110798893 Common ackA acetate kinase CPF_0208 162 COG0282 ackA, Acetate kinase Energy production and conversion 110799385 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CPF_1341 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 110800155 Common - hypothetical protein CPF_0275 93 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 110799756 Common - phosphodiesterase/nucleotide pyrophosphatase family protein CPF_1625 39 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 110800453 Common aroK shikimate kinase CPF_0694 202 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 110801252 Common - isochorismatase family protein CPF_0569 35 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110799606 Common - HesA/MoeB/ThiF family protein CPF_0064 177 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 110799834 Common - polysaccharide biosynthesis protein CPF_0604 68 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110798895 Common rnfB ferredoxin CPF_1321 101 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 110798995 Common - hypothetical protein CPF_1761 10 COG3428 COG3428, Predicted membrane protein Function unknown 110800289 Common yyaC putative sporulation protein YyaC CPF_2985 14 None None None 110799532 Pathogen - hypothetical protein CPF_1004 1 None None None 110800892 Common - hypothetical protein CPF_1902 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 110801202 Common - coenzyme B12-dependent glycerol dehydratase, large subunit CPF_1173 13 COG4909 PduC, Propanediol dehydratase, large subunit Secondary metabolites biosynthesis, transport, and catabolism 110800927 Pathogen - hypothetical protein CPF_0937 1 None None None 110799275 Common - hesB family protein CPF_0653 1 COG0316 IscA, Uncharacterized conserved protein Function unknown 110799542 Common - putative enterotoxin CPF_1467 13 COG5162 COG5162, Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) Transcription 110800160 Pathogen - hypothetical protein CPF_1564 1 None None None 110798621 Common - hypothetical protein CPF_2310 1 None None None 110800062 Common - hypothetical protein CPF_1131 2 None None None 110800239 Common fucI L-fucose isomerase CPF_1048 19 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 110801199 Common - hypothetical protein CPF_0154 4 None None None 110799075 Common - hypothetical protein CPF_2058 17 COG3874 COG3874, Uncharacterized conserved protein Function unknown 110798781 Common - putative maltose/maltodextrin ABC transporter, ATP-binding protein CPF_2654 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110800864 Pathogen - hypothetical protein CPF_1354 1 None None None 110798763 Common - acetyltransferase, GNAT family CPF_1342 53 COG0456 RimI, Acetyltransferases General function prediction only 110799445 Common - Ser/Thr protein phosphatase family protein CPF_2821 98 COG0622 COG0622, Predicted phosphoesterase General function prediction only 110800814 Common - hydrolase, alpha/beta fold family CPF_0769 22 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110801437 Common - sensor histidine kinase CPF_2503 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110801349 Common - hypothetical protein CPF_1225 1 None None None 110800754 Common - putative cell division protein DivIVA CPF_2105 35 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 110801163 Common - MATE efflux family protein CPF_0330 174 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110799551 Common arsC anaerobic sulfite reductase, subunit C CPF_1691 127 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110799120 Common - sensory box protein/histidinol phosphate phosphatase family protein CPF_0801 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 110799031 Common - ABC transporter, permease protein CPF_0746 70 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110799700 Pathogen - hypothetical protein CPF_1561 1 None None None 110801167 Common nusB transcription antitermination protein NusB CPF_2078 198 COG0781 NusB, Transcription termination factor Transcription 110799227 Common groEL chaperonin GroEL CPF_2573 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110800081 Common moaC molybdenum cofactor biosynthesis protein C CPF_2340 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110800487 Common - polysaccharide deacetylase family protein CPF_1802 74 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110800903 Common - hypothetical protein CPF_0055 3 None None None 110800821 Common - transcriptional regulator, LysR family CPF_0727 189 COG0583 LysR, Transcriptional regulator Transcription 110799726 Common holA DNA polymerase III subunit delta CPF_2300 41 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 110798824 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CPF_1928 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110800315 Common - ABC transporter, ATP-binding protein CPF_2288 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110800658 Common folC FolC bifunctional protein CPF_2174 221 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 110800117 Common - N-acetylmuramoyl-L-alanine amidase, family 2 CPF_0587 27 COG5632 COG5632, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110799436 Common - acetyltransferase, GNAT family CPF_1061 8 None None None 110800533 Pathogen - M23 peptidase domain protein CPF_2390 1 None None None 110799136 Pathogen - hypothetical protein CPF_0104 1 None None None 110799708 Common - TldD/PmbA family protein CPF_0324 165 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 110799280 Pathogen - hypothetical protein CPF_1449 1 None None None 110799038 Pathogen - hypothetical protein CPF_0192 1 None None None 110800538 Common - MOSC domain protein CPF_2044 31 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 110801097 Common greA transcription elongation factor GreA CPF_1471 159 COG0782 GreA, Transcription elongation factor Transcription 110799147 Common yyaC putative sporulation protein YyaC CPF_2444 14 None None None 110800468 Common mscL large-conductance mechanosensitive channel CPF_0167 140 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110798989 Common - hypothetical protein CPF_1015 2 None None None 110800377 Pathogen - hypothetical protein CPF_0536 1 None None None 110800730 Common - D-alanyl-D-alanine carboxypeptidase family protein CPF_2056 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110798684 Common - anaerobic sulfite reductase, A subunit CPF_1789 31 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 110798652 Common - putative zinc ABC transporter, ATP-binding protein CPF_1709 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 110800281 Common murG N-acetylglucosaminyl transferase CPF_2320 209 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110800766 Common nadD nicotinic acid mononucleotide adenyltransferase CPF_2380 187 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 110799561 Common - acyltransferase family protein CPF_0199 22 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 110799206 Common rpsO 30S ribosomal protein S15 CPF_1935 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 110800104 Common - thioredoxin family protein CPF_1847 14 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110801300 Pathogen - hypothetical protein CPF_0790 1 None None None 110800295 Common - uracil-xanthine permease CPF_0385 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110800899 Common - putative adenine-specific DNA methyltransferase CPF_1606 48 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 110799963 Common - CBS/transporter associated domain protein CPF_0439 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110800667 Common - RNA methyltransferase, TrmH family, group 3 CPF_2734 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110801128 Common rpmI 50S ribosomal protein L35 CPF_2145 192 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 110800588 Pathogen - hypothetical protein CPF_1732 1 None None None 110799996 Common - hypothetical protein CPF_0093 35 COG1416 COG1416, Uncharacterized conserved protein Function unknown 110799426 Common polA DNA polymerase I CPF_2250 219 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 110799287 Common - Fibronectin type III domain protein CPF_0685 8 None None None 110799453 Common - aminotransferase, class V CPF_1720 233 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110798789 Common - heparinase II/III-like protein CPF_0406 17 None None None 110800405 Common - putative zinc-dependent hydrolase CPF_2755 65 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110800614 Common cbiN cobalt transport protein CbiN CPF_0186 41 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 110799483 Pathogen - hypothetical protein CPF_1851 1 None None None 110798746 Pathogen - hypothetical protein CPF_2088 1 None None None 110801055 Common rbr rubrerythrin CPF_0133 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 110800132 Common - hypothetical protein CPF_0958 2 None None None 110798604 Common - hypothetical protein CPF_1628 44 COG2035 COG2035, Predicted membrane protein Function unknown 110799631 Common ispA geranyltranstransferase CPF_2074 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 110798944 Pathogen - hypothetical protein CPF_1862 1 None None None 110800736 Common - hypothetical protein CPF_1282 18 COG1993 COG1993, Uncharacterized conserved protein Function unknown 110799896 Common - hypothetical protein CPF_1440 6 None None None 110800435 Common - hypothetical protein CPF_1187 28 COG4828 COG4828, Predicted membrane protein Function unknown 110800215 Common - RNA polymerase sigma-70 factor, ECF subfamily CPF_0712 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110799317 Common - iron chelate uptake ABC transporter, FeCT family, permease protein CPF_1297 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110800213 Common kdpA potassium-transporting ATPase subunit A CPF_1210 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 110799066 Common - hypothetical protein CPF_0940 7 COG2188 PhnF, Transcriptional regulators Transcription 110800832 Common speD S-adenosylmethionine decarboxylase CPF_0527 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 110800333 Common - NAD-dependent 4-hydroxybutyrate dehydrogenase CPF_0518 167 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110800092 Common pcrA ATP-dependent DNA helicase PcrA CPF_2542 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110798590 Common - hypothetical protein CPF_1469 11 None None None 110798758 Common - putative beta-N-acetylhexosaminidase CPF_0259 184 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 110800742 Common fruK 1-phosphofructokinase CPF_0565 97 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 110800858 Common pyrC dihydroorotase, multifunctional complex type CPF_1385 222 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110800313 Common - glutaredoxin-like protein, YruB-family CPF_2749 25 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110801069 Common glnS glutaminyl-tRNA synthetase CPF_0626 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110798805 Common atpB F0F1 ATP synthase subunit A CPF_2458 195 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 110798851 Common - HAD superfamily (subfamily IA) hydrolase, TIGR02254 CPF_0757 99 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110801110 Common - phage prohead protease, HK97 family CPF_1585 31 COG3740 COG3740, Phage head maturation protease General function prediction only 110800888 Common - putative tetracycline resistance protein CPF_1490 159 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110798599 Pathogen - acetyltransferase, GNAT family CPF_1129 1 None None None 110800501 Common - electron transfer flavoprotein, beta subunit/FixA family protein CPF_2583 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 110800369 Common - DNA-binding response regulator CPF_1403 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110800466 Common carB carbamoyl phosphate synthase large subunit CPF_2897 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 110800954 Common - homocysteine S-methyltransferase family protein CPF_1670 163 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 110800202 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase CPF_0480 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 110800036 Pathogen - hypothetical protein CPF_1190 1 None None None 110798790 Common - putative regulatory protein CPF_0753 37 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 110799204 Pathogen - hypothetical protein CPF_1447 1 None None None 110800274 Common - amino acid ABC transporter, amino acid-binding protein CPF_1531 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110799013 Common - peptidase, M50 family CPF_1918 81 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110800033 Common rplV 50S ribosomal protein L22 CPF_2709 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 110801015 Pathogen - hypothetical protein CPF_1063 1 None None None 110799166 Common - iron compound ABC transporter, iron compound-binding protein CPF_0807 73 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110800727 Common - hypothetical protein CPF_2352 6 COG2445 COG2445, Uncharacterized conserved protein Function unknown 110799952 Common - hypothetical protein CPF_0601 1 None None None 110799347 Common - thiamin biosynthesis protein ThiI CPF_2474 63 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 110800929 Common - acetyltransferase, GNAT family CPF_1619 23 COG0456 RimI, Acetyltransferases General function prediction only 110799365 Common yabQ spore cortex biosynthesis protein YabQ CPF_2799 5 None None None 110798583 Pathogen - hypothetical protein CPF_1234 1 None None None 110798889 Pathogen - hypothetical protein CPF_2867 1 None None None 110800423 Common tdk thymidine kinase CPF_2468 86 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 110801138 Common - HDIG domain protein CPF_1275 6 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110800303 Common - putative branched-chain amino acid aminotransferase CPF_1273 152 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110800516 Common - alpha-N-acetylglucosaminidase family protein CPF_0859 18 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110800920 Common cdd cytidine deaminase CPF_2273 122 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 110801372 Common virS sensor histidine kinase VirS CPF_1751 11 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 110798998 Common - glutaminase CPF_2251 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 110799237 Common - putative catabolite control protein A CPF_2863 129 COG1609 PurR, Transcriptional regulators Transcription 110799156 Common greA transcription elongation factor GreA CPF_2782 204 COG0782 GreA, Transcription elongation factor Transcription 110799930 Common - hypothetical protein CPF_1066 1 None None None 110799579 Common - hypothetical protein CPF_1285 11 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110800134 Common - hypothetical protein CPF_2314 1 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 110800351 Common - transcriptional regulator, RpiR family CPF_0182 127 COG1737 RpiR, Transcriptional regulators Transcription 110799167 Common - oligopeptide/dipeptide ABC transporter, oligopeptide/dipeptide-binding protein CPF_2555 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110799362 Common galU UTP-glucose-1-phosphate uridylyltransferase CPF_0487 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110799665 Common acpS 4'-phosphopantetheinyl transferase CPF_0287 116 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 110798651 Common purN phosphoribosylglycinamide formyltransferase CPF_0676 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 110801228 Common - coproporphyrinogen III oxidase CPF_2190 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 110800807 Common - hypothetical protein CPF_1451 49 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110799443 Common - 7-alpha-hydroxysteroid dehydrogenase CPF_1154 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110799508 Common - heavy-metal-associated domain protein CPF_1453 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 110800604 Common - glycosyl transferase, group 2 family protein CPF_0913 35 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110799782 Common - hypothetical protein CPF_0981 30 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 110798838 Common - putative stage IV sporulation protein CPF_2277 14 None None None 110798936 Common - acetyltransferase, GNAT family CPF_1157 6 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 110800302 Common - hydrolase, alpha/beta fold family CPF_2244 76 COG2267 PldB, Lysophospholipase Lipid metabolism 110801044 Common mgtA magnesium-translocating P-type ATPase CPF_1153 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110801106 Common - phytoene dehydrogenase family protein CPF_1810 85 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110798735 Common folBK dihydroneopterin aldolase/ 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CPF_1277 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 110798947 Common dnaN DNA polymerase III subunit beta CPF_0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 110800866 Common - dipeptidase family protein CPF_2183 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 110798668 Common - hypothetical protein CPF_1786 3 None None None 110798908 Common - DNA-binding response regulator CPF_0498 132 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 110801277 Common tuf elongation factor Tu CPF_2716 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 110799595 Common - 5'-nucleotidase, lipoprotein e(P4) family CPF_0190 27 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 110800494 Common - PTS system, mannose/fructose/sorbose family, IID component CPF_0403 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 110800027 Common - nitrite/sulfite reductase-like protein CPF_0526 153 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 110799513 Common - ABC transporter, ATP-binding protein/permease protein CPF_2580 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110799214 Common - AP endonuclease, family 2 CPF_1649 3 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110799092 Common - AAA domain family protein CPF_0631 28 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 110799585 Common feoA ferrous iron transport protein A CPF_1010 12 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110799575 Common - hypothetical protein CPF_2425 22 COG3601 COG3601, Predicted membrane protein Function unknown 110800005 Common - hypothetical protein CPF_1222 6 None None None 110801288 Common aspS aspartyl-tRNA synthetase CPF_2188 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110800441 Common sun ribosomal RNA small subunit methyltransferase B CPF_1994 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 110800448 Common - PRC-barrel domain protein CPF_2036 1 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 110799324 Pathogen - hypothetical protein CPF_0431 1 None None None 110799587 Pathogen - hypothetical protein CPF_2605 1 None None None 110800296 Common buk butyrate kinase CPF_2656 141 COG3426 COG3426, Butyrate kinase Energy production and conversion 110798624 Common - hypothetical protein CPF_1459 9 None None None 110799746 Common - putative oxidoreductase CPF_2776 217 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110800877 Common cls cardiolipin synthase CPF_1683 156 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110798566 Common - uracil-xanthine permease CPF_1422 137 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110800532 Common - ABC transporter, permease protein CPF_1791 181 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 110799462 Common rplF 50S ribosomal protein L6 CPF_2699 234 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 110799222 Common - transcriptional regulator, AraC family CPF_0450 134 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110800346 Common ilvE branched-chain amino acid aminotransferase CPF_1772 202 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110799903 Common rpoC DNA-directed RNA polymerase subunit beta' CPF_2721 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 110800551 Common - TldD/PmbA family protein CPF_0323 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 110801404 Common - hypothetical protein CPF_1877 5 COG1289 COG1289, Predicted membrane protein Function unknown 110799914 Common - major facilitator family transporter CPF_2367 16 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110800122 Common ulaA ascorbate-specific PTS system enzyme IIC CPF_0503 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 110800419 Common - hypothetical protein CPF_0994 2 COG5658 COG5658, Predicted integral membrane protein Function unknown 110800592 Common - hypothetical protein CPF_2480 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 110801037 Common - oxidoreductase, short-chain dehydrogenase/reductase family CPF_0373 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110799041 Common rpoA DNA-directed RNA polymerase subunit alpha CPF_2685 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 110801022 Common - sensor histidine kinase CPF_1112 100 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 110800480 Common prs phosphoribosylpyrophosphate synthetase CPF_1800 233 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110800146 Common - Ppx/GppA phosphatase family protein CPF_1916 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 110800980 Common - sensor histidine kinase/response regulator CPF_1764 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110800697 Common - conserved hypothetical protein TIGR00150 CPF_2422 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 110798747 Common - hypothetical protein CPF_1730 2 None None None 110800987 Common - ROK family protein CPF_0181 150 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110800844 Common - hypothetical protein CPF_1565 5 COG2606 EbsC, Uncharacterized conserved protein Function unknown 110801134 Common purD phosphoribosylamine--glycine ligase CPF_0678 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 110799767 Common pgk phosphoglycerate kinase CPF_1510 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 110800993 Common maa maltose transacetylase CPF_2912 86 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110799113 Common - hypothetical protein CPF_2611 27 None None None 110800479 Pathogen - hypothetical protein CPF_1739 1 None None None 110800415 Common treC alpha,alpha-phosphotrehalase CPF_0542 152 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110800261 Common efp elongation factor P CPF_2089 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 110799823 Common rfbA glucose-1-phosphate thymidylyltransferase CPF_0479 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110799986 Pathogen - hypothetical protein CPF_0328 1 None None None 110800659 Common glgP glycogen/starch/alpha-glucan phosphorylase CPF_2646 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 110801426 Common - hypothetical protein CPF_1013 5 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 110800574 Common - hypothetical protein CPF_1748 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 110799650 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CPF_2114 207 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 110801020 Pathogen - hypothetical protein CPF_1343 1 None None None 110801238 Common - hypothetical protein CPF_1069 2 None None None 110801264 Common mreC rod shape-determining protein MreC CPF_2397 141 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 110800914 Common - AgrB family protein CPF_0865 2 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 110800978 Common - putative csfB protein CPF_2764 1 None None None 110798691 Common - GTP-binding protein CPF_0103 187 COG1160 COG1160, Predicted GTPases General function prediction only 110799869 Common gyrA DNA topoisomerase IV subunit A CPF_2325 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110799090 Common - Holliday junction resolvase-like protein CPF_2031 177 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 110800775 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CPF_0227 137 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110798928 Common - Na+/H+ antiporter family protein CPF_2850 79 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 110799099 Common - hypothetical protein CPF_0552 7 None None None 110799077 Common - ABC transporter, permease protein CPF_2339 141 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 110801176 Common - hypothetical protein CPF_0962 2 None None None 110798964 Common hisS histidyl-tRNA synthetase CPF_2189 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110799719 Common raiA ribosomal subunit interface protein CPF_2430 172 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 110799615 Common - alcohol dehydrogenase, iron-containing CPF_0885 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110801354 Common - hypothetical protein CPF_2600 3 None None None 110800631 Common rpmA 50S ribosomal protein L27 CPF_2383 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 110799257 Common - hypothetical protein CPF_0761 4 None None None 110800749 Common mutL DNA mismatch repair protein CPF_1359 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 110799182 Pathogen - hypothetical protein CPF_1577 1 None None None 110799845 Common - PTS system, IIBC component CPF_0422 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110799657 Common - hypothetical protein CPF_1484 6 None None None 110798694 Pathogen - hypothetical protein CPF_0228 1 None None None 110799913 Common dnaG DNA primase CPF_2265 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 110799771 Common - putative type II restriction enzyme HphI CPF_1468 30 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 110798912 Common - hypothetical protein CPF_1473 4 None None None 110800042 Common araD L-ribulose-5-phosphate 4-epimerase CPF_0648 127 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 110799048 Pathogen - hypothetical protein CPF_1355 1 None None None 110800358 Pathogen - hypothetical protein CPF_0660 1 None None None 110799023 Pathogen - hypothetical protein CPF_1152 1 None None None 110799334 Common dinB DNA polymerase IV CPF_1818 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110798868 Common hpkA sensor histidine kinase CPF_1195 223 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110800934 Common - transcriptional regulator CPF_1136 132 COG1733 COG1733, Predicted transcriptional regulators Transcription 110799478 Common - 5-formyltetrahydrofolate cyclo-ligase family protein CPF_2633 172 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 110800886 Common gyrA DNA gyrase subunit A CPF_0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110799293 Common - glycosyl hydrolase, family 85 CPF_0815 19 COG4724 COG4724, Endo-beta-N-acetylglucosaminidase D Carbohydrate transport and metabolism 110799731 Common - putative 8-oxoguanine DNA glycosylase CPF_2577 24 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 110801340 Common - hypothetical protein CPF_1038 3 None None None 110798848 Common rplE 50S ribosomal protein L5 CPF_2702 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 110799923 Common glpP glycerol uptake operon antiterminator CPF_2877 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 110800585 Pathogen - hypothetical protein CPF_1122 1 None None None 110801090 Common - S4 domain protein CPF_2801 58 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 110800254 Common - putative Cof-like hydrolase CPF_1058 42 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110800617 Common cobB cobalamin biosynthesis protein CobB CPF_1294 149 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 110798774 Common pdaA delta-lactam-biosynthetic de-N-acetylase CPF_2122 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110800571 Pathogen - hypothetical protein CPF_0230 1 None None None 110801003 Pathogen - putative K+-transporting ATPase, F subunit CPF_1209 1 None None None 110799355 Common - hypothetical protein CPF_2869 14 COG3859 COG3859, Predicted membrane protein Function unknown 110799289 Common - hypothetical protein CPF_0355 2 None None None 110799282 Common - spore germination protein CPF_0628 2 None None None 110800363 Common - GTPase EngB CPF_1643 201 COG0218 COG0218, Predicted GTPase General function prediction only 110800200 Common - glycosyl transferase, group 1 CPF_0473 4 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110800792 Common - ABC transporter, ATP-binding protein CPF_0302 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110799754 Common - hypothetical protein CPF_1075 4 None None None 110800137 Common - hypothetical protein CPF_2884 21 COG3949 COG3949, Uncharacterized membrane protein Function unknown 110801154 Common - vanZ family protein CPF_2896 8 None None None 110799574 Common - putative exo-alpha-sialidase CPF_0721 18 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 110799417 Common sigF sporulation sigma factor SigF CPF_2305 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110800535 Pathogen - hypothetical protein CPF_1560 1 None None None 110799129 Common rplO 50S ribosomal protein L15 CPF_2695 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 110799971 Common - nucleotidyltransferase domain protein CPF_2213 1 None None None 110799176 Common - potassium transporter CPF_1235 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 110800243 Common - hypothetical protein CPF_0005 12 None None None 110800701 Common - site-specific recombinase, resolvase family CPF_0138 44 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110799911 Common pdp pyrimidine-nucleoside phosphorylase CPF_2062 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 110800114 Common - carbohydrate kinase family protein CPF_0288 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 110800169 Common guaB inositol-5-monophosphate dehydrogenase CPF_2558 244 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 110800386 Common rpiB ribose-5-phosphate isomerase B CPF_2463 129 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 110800555 Pathogen - hypothetical protein CPF_0991 1 None None None 110798675 Common - cell wall binding repeat protein CPF_0611 8 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110801005 Common - putative capK protein CPF_0472 18 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 110799816 Common - FemAB family protein CPF_2347 24 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 110799384 Common - voltage-gated chloride channel family protein CPF_0661 16 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110800800 Common - electron transfer flavoprotein, beta subunit/FixA family protein CPF_0308 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 110798792 Common - amino acid ABC transporter, amino acid-binding protein/permease protein, His/Glu/Gln/Arg/opine family CPF_2350 195 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110800771 Pathogen - hypothetical protein CPF_1037 1 None None None 110799909 Common - DNA-binding response regulator CPF_0226 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110799663 Common - hypothetical protein CPF_1456 62 COG2898 COG2898, Uncharacterized conserved protein Function unknown 110798902 Common - hypothetical protein CPF_2895 1 None None None 110801282 Common - putative cell division protein CPF_0297 97 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 110800972 Common - hypothetical protein CPF_2488 22 COG4769 COG4769, Predicted membrane protein Function unknown 110800101 Common - ABC-2 type transporter, permease protein CPF_0263 77 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110798761 Common - ABC transporter, ATP-binding protein CPF_1736 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110799827 Common - ABC transporter, ATP-binding protein CPF_0264 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110799735 Common - putative sensor histidine kinase CPF_2673 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110800894 Common - helicase, RecD/TraA family CPF_2433 148 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 110801365 Common - CBS domain/MgtE intracellular domain protein CPF_1530 178 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 110801070 Common - DNA-binding response regulator, LytTr family CPF_1752 133 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 110799277 Pathogen - hypothetical protein CPF_2544 1 None None None 110800171 Common cobS cobalamin-5-phosphate synthase CPF_1291 136 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 110799146 Common - hypothetical protein CPF_0278 5 None None None 110800470 Common - hypothetical protein CPF_0975 2 None None None 110799269 Common - hypothetical protein CPF_2659 25 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 110798708 Common - ABC transporter, permease protein CPF_1479 231 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110801379 Common - hypothetical protein CPF_0636 4 None None None 110799264 Common atpH F0F1 ATP synthase subunit delta CPF_2455 191 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 110801296 Common - putative phage infection protein CPF_2915 31 COG1511 COG1511, Predicted membrane protein Function unknown 110799881 Common - TrpR-like protein YerC/YecD CPF_2643 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 110799871 Common hydA iron hydrogenase CPF_2655 182 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110800644 Common - hypothetical protein CPF_0112 2 None None None 110799800 Common grpE co-chaperone GrpE CPF_2291 233 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 110800809 Common - bacterial sugar transferase family protein CPF_0595 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110798961 Common thiC thiamine biosynthesis protein ThiC CPF_0670 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 110798826 Common - putative ethanolamine utilization protein EutH CPF_2492 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 110798710 Common - hypothetical protein CPF_1828 17 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 110799775 Common - transcriptional regulator, Crp/Fnr family CPF_0778 174 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110800635 Common - spore germination protein CPF_0629 15 None None None 110800787 Pathogen - hypothetical protein CPF_1611 1 None None None 110801079 Common - putative sugar isomerase CPF_2961 46 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 110799785 Common - glycosyl hydrolase, family 20 CPF_1103 22 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 110800949 Common cotJC spore coat protein CotJC CPF_1068 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 110801050 Common - hypothetical protein CPF_1959 53 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 110799138 Common - MATE efflux family protein CPF_2828 186 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110801088 Common - glyoxalase family protein CPF_0453 58 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110800162 Common - putative arginine/ornithine antiporter CPF_0377 79 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110800699 Common - radical SAM domain protein CPF_1039 45 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 110799313 Common nadC nicotinate-nucleotide pyrophosphorylase CPF_0384 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 110800194 Common - sodium:dicarboxylate symporter family protein CPF_1370 112 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110800576 Common - HD domain protein CPF_1673 52 None None None 110800780 Common rplI 50S ribosomal protein L9 CPF_2972 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 110799884 Common - redox-sensing transcriptional repressor Rex CPF_2586 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 110800599 Common - mutS domain protein CPF_2411 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110799854 Common - RNA methyltransferase, TrmH family CPF_2141 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110799683 Common - hypothetical protein CPF_2245 3 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 110801338 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CPF_2037 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 110799636 Common secD preprotein translocase subunit SecD CPF_2197 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 110799007 Common - carbonic anhydrase CPF_0414 40 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 110799695 Pathogen - hypothetical protein CPF_2091 1 None None None 110798654 Common cls cardiolipin synthetase CPF_0354 147 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110800270 Common - hypothetical protein CPF_0700 2 None None None 110798942 Common pth peptidyl-tRNA hydrolase CPF_2808 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 110800669 Common - hypothetical protein CPF_1534 1 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110801057 Common - hypothetical protein CPF_0639 2 None None None 110799898 Common kdpD sensor histidine kinase KdpD CPF_1213 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110799860 Common - hypothetical protein CPF_0332 19 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 110801302 Common - protein phosphatase 2C family protein CPF_1992 136 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 110798587 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC CPF_1412 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110800199 Common - putative glycerol-3-phosphate transporter CPF_0222 153 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110799640 Common scrR sucrose operon repressor CPF_1784 128 COG1609 PurR, Transcriptional regulators Transcription 110800432 Common - hypothetical protein CPF_0022 5 None None None 110800854 Common aroB 3-dehydroquinate synthase CPF_0688 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 110798974 Pathogen - hypothetical protein CPF_0197 1 None None None 110801334 Common - histidinol phosphate phosphatase family protein CPF_1229 33 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110798787 Common gmk guanylate kinase CPF_2001 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 110799553 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase CPF_0677 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 110799106 Common - ABC transporter, ATP-binding protein CPF_0446 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110799811 Common - sensor histidine kinase CPF_1057 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110799949 Common cbiD cobalt-precorrin-6A synthase CPF_1434 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 110801126 Common - ATP-dependent RNA helicase, DEAD/DEAH box family CPF_1650 244 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110799942 Common - MgtC family protein CPF_0572 117 COG1285 SapB, Uncharacterized membrane protein Function unknown 110798754 Common arsC arsenate reductase ArsC CPF_0834 111 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110799481 Common - hypothetical protein CPF_2107 52 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 110800612 Common arsR arsenical resistance operon repressor CPF_0833 162 COG0640 ArsR, Predicted transcriptional regulators Transcription 110800060 Common spoIIID stage III sporulation protein D CPF_2446 15 None None None 110801095 Common - creatininase CPF_0751 85 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110798697 Common - putative cobalt ABC transporter, ATP-binding protein CPF_1835 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110800461 Common nrdA ribonucleotide-diphosphate reductase subunit alpha CPF_2671 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 110799458 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase CPF_2073 218 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 110799451 Common - RNA-metabolising metallo-beta-lactamase family protein CPF_2028 160 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 110801310 Common - hypothetical protein CPF_1399 1 None None None 110799724 Common - hydrolase, NUDIX family CPF_1043 26 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110798601 Common eutT ethanolamine utilization cobalamin adenosyltransferase CPF_0897 12 COG4812 EutT, Ethanolamine utilization cobalamin adenosyltransferase Amino acid transport and metabolism 110800521 Common - ribosomal protein L7AE family CPF_2720 14 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 110800158 Common - sodium:dicarboxylate symporter family protein CPF_1223 133 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110800506 Common virJ sensor histidine kinase CPF_2355 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110799271 Common - peptidase, U32 family CPF_2024 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 110799402 Common xpt xanthine phosphoribosyltransferase CPF_0319 60 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110799492 Common - hypothetical protein CPF_1605 8 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 110798909 Common - hypothetical protein CPF_0876 106 COG0393 COG0393, Uncharacterized conserved protein Function unknown 110800924 Common - putative N-acetylmuramoyl-L-alanine amidase CPF_1753 18 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110800225 Common - hypothetical protein CPF_2262 33 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 110799534 Common spoIIGA Sporulation factor SpoIIGA CPF_2016 9 None None None 110799425 Pathogen - hypothetical protein CPF_0709 1 None None None 110799556 Common - proton/sodium-glutamate symporter CPF_0756 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110798878 Pathogen - hypothetical protein CPF_1352 1 None None None 110798623 Common cbiE precorrin-6y C5,15-methyltransferase (decarboxylating) CPF_1433 71 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 110800451 Pathogen - hypothetical protein CPF_2990 1 None None None 110801285 Pathogen - hypothetical protein CPF_0943 1 None None None 110800752 Common - helicase, SNF2/RAD54 family CPF_1878 152 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 110799119 Common - hypothetical protein CPF_1006 9 None None None 110798834 Common rplR 50S ribosomal protein L18 CPF_2698 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 110800718 Common glxK glycerate kinase CPF_0854 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 110799434 Common - hypothetical protein CPF_0637 35 COG0714 COG0714, MoxR-like ATPases General function prediction only 110798618 Common - hypothetical protein CPF_1268 7 None None None 110800287 Common - ABC transporter, permease/ATP-binding protein CPF_0367 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110800823 Pathogen - hypothetical protein CPF_0257 1 None None None 110801140 Common - cation efflux family protein CPF_1874 52 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110801329 Common - hypothetical protein CPF_1979 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 110801197 Common - acetyltransferase, GNAT family CPF_0066 128 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110799440 Common - hypothetical protein CPF_1231 1 None None None 110799702 Common - hypothetical protein CPF_2936 9 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 110800192 Common - hypothetical protein CPF_2934 1 None None None 110801169 Common cbiC precorrin-8X methylmutase CPF_1435 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 110799122 Common - hypothetical protein CPF_2563 1 None None None 110800083 Common rfbB dTDP-glucose 4,6-dehydratase CPF_0600 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 110799935 Common aroF 3-deoxy-7-phosphoheptulonate synthase CPF_0687 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 110800905 Common lacA galactoside O-acetyltransferase CPF_0251 210 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110798952 Common - putative beta-lactamase CPF_1388 50 COG2367 PenP, Beta-lactamase class A Defense mechanisms 110800421 Common aroC chorismate synthase CPF_0690 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 110800799 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CPF_1326 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110798665 Common - hypothetical protein CPF_2205 1 None None None 110800720 Pathogen - putative type IV pilin CPF_2566 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110798882 Common - PTS system, IIA component CPF_1717 7 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 110800870 Common rplD 50S ribosomal protein L4 CPF_2713 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 110800235 Common secG preprotein translocase subunit SecG CPF_1503 9 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 110799593 Common metK S-adenosylmethionine synthetase CPF_2435 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 110799079 Common - hypothetical protein CPF_0224 2 None None None 110799070 Common thiG thiazole synthase CPF_1854 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 110800218 Common - DNA-binding response regulator CPF_2180 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110800009 Common - pentapeptide repeat protein CPF_1189 1 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110799291 Common mglC beta-methylgalactoside transporter inner membrane component CPF_1550 108 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 110798836 Common - acyl-ACP thioesterase family protein CPF_2954 21 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 110799094 Common - PRC-barrel domain protein CPF_2013 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110801049 Pathogen - hypothetical protein CPF_1132 1 None None None 110799300 Common - HAD-superfamily hydrolase, subfamily IIB CPF_0594 146 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110800077 Common - RNA-binding protein CPF_2426 223 COG2183 Tex, Transcriptional accessory protein Transcription 110800496 Common clpX ATP-dependent protease ATP-binding subunit CPF_1646 232 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 110799132 Common - putative dihydrouridine synthase CPF_2783 219 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110801165 Common - sensor histidine kinase CPF_2345 108 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 110801042 Common xpt xanthine phosphoribosyltransferase CPF_1498 27 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110799000 Common tpiA triosephosphate isomerase CPF_1509 218 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 110801309 Common malQ 4-alpha-glucanotransferase CPF_2647 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 110801254 Common - hypothetical protein CPF_1723 1 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 110800558 Common pstB phosphate ABC transporter, ATP-binding protein CPF_0621 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 110799511 Common - hypothetical protein CPF_2766 1 None None None 110801226 Common - 67 kDa myosin-cross-reactive antigen family protein CPF_0365 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 110800485 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CPF_2116 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110799618 Common - rubredoxin/flavodoxin/oxidoreductase CPF_1269 229 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110800541 Common - DNA-binding protein CPF_1603 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 110800007 Common - hypothetical protein CPF_1146 9 None None None 110800058 Common rnfE SoxR-reducing system protein RsxE CPF_1319 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 110800446 Common - iron compound ABC transporter, iron compound-binding protein CPF_0440 119 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110800099 Common - acetyltransferase, GNAT family CPF_0759 3 None None None 110799083 Common - hypothetical protein CPF_1228 4 None None None 110800719 Common - DNA topoisomerase IV subunit B CPF_2326 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110799353 Pathogen - hypothetical protein CPF_1334 1 None None None 110799583 Common - putative potassium uptake protein CPF_2142 142 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110799284 Common rnpA ribonuclease P CPF_2996 4 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 110799499 Common dut deoxyuridine 5-triphosphate nucleotidohydrolase CPF_0669 107 COG0756 Dut, dUTPase Nucleotide transport and metabolism 110799547 Common - hypothetical protein CPF_2853 10 COG3937 COG3937, Uncharacterized conserved protein Function unknown 110799203 Common - amino acid permease family protein CPF_0159 108 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801108 Common - putative lipoprotein CPF_1466 8 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110800437 Common - voltage-gated chloride channel family protein CPF_0570 161 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110800489 Common - DNA-binding protein CPF_1021 2 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 110800354 Common - ABC transporter, substrate-binding protein CPF_1477 97 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110801279 Common - HD domain protein CPF_2827 2 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110799892 Common - ethanolamine utilization protein CPF_0895 153 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110800085 Common - thiamine monophosphate synthase family protein CPF_1852 72 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110801100 Common - hypothetical protein CPF_2384 5 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 110798612 Common relA GTP pyrophosphokinase CPF_2193 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 110799613 Common rbgA ribosomal biogenesis GTPase CPF_1961 96 COG1161 COG1161, Predicted GTPases General function prediction only 110798921 Common - sensor histidine kinase CPF_0460 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110799805 Common - putative lipoprotein CPF_1780 7 None None None 110799693 Common rpsA 30S ribosomal protein S1 CPF_2405 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 110799464 Common - FCD domain protein CPF_0306 123 COG2186 FadR, Transcriptional regulators Transcription 110799056 Pathogen - hypothetical protein CPF_1100 1 None None None 110799925 Common treR trehalose operon repressor CPF_0543 123 COG2188 PhnF, Transcriptional regulators Transcription 110800971 Common - hypothetical protein CPF_1396 25 COG4866 COG4866, Uncharacterized conserved protein Function unknown 110799245 Common pyrR pyrimidine regulatory protein PyrR CPF_2103 126 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 110801040 Common iolD myo-inositol catabolism protein IolD CPF_0084 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 110799679 Common - hypothetical protein CPF_0359 30 COG3972 COG3972, Superfamily I DNA and RNA helicases General function prediction only 110800034 Common - hypothetical protein CPF_2644 6 COG2013 COG2013, Uncharacterized conserved protein Function unknown 110799932 Common - hypothetical protein CPF_1166 2 None None None 110799521 Common brnQ branched-chain amino acid transport system II carrier protein CPF_0392 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 110798597 Common - V-type ATPase, E subunit CPF_1893 19 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 110801351 Common fucU fucose operon protein FucU CPF_1050 46 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 110800881 Common - hydrolase, NUDIX family CPF_0794 29 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110799959 Common - putative lipoprotein CPF_0435 18 None None None 110799629 Common msrA methionine sulfoxide reductase A CPF_2913 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110798951 Common alr alanine racemase CPF_0861 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 110798935 Common - acetyltransferase, GNAT family CPF_0811 73 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110799633 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase CPF_0598 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 110800839 Common - hypothetical protein CPF_1563 1 COG5460 COG5460, Uncharacterized conserved protein Function unknown 110800237 Common ribD riboflavin biosynthesis protein RibD CPF_0546 230 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 110801204 Common - endodeoxyribonuclease, RusA family protein CPF_2497 2 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 110801383 Common - transcriptional regulator, AsnC family CPF_0706 87 COG1522 Lrp, Transcriptional regulators Transcription 110799778 Common - vanW-related protein CPF_1397 33 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 110801214 Pathogen - hypothetical protein CPF_0508 1 None None None 110799642 Common - hypothetical protein CPF_2862 8 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 110798585 Pathogen - hypothetical protein CPF_2559 1 None None None 110799107 Common recQ ATP-dependent DNA helicase RecQ CPF_0327 235 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 110801374 Common comB 2-phosphosulfolactate phosphatase CPF_2881 48 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 110798803 Common - hypothetical protein CPF_2927 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 110801235 Common hpt hypoxanthine phosphoribosyltransferase CPF_2787 153 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 110801211 Common - capsule chain length determinant protein CPF_0918 33 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 110800031 Common - hypothetical protein CPF_0881 37 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110799239 Common - Mrp/NBP35 ATP-binding family protein CPF_2835 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110801062 Common recF recombination protein F CPF_0004 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 110799101 Common xerD tyrosine recombinase XerD CPF_2063 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110800671 Common - HIT family protein CPF_2281 231 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 110800291 Common - hypothetical protein CPF_1708 1 None None None 110799765 Common - sensory box histidine kinase CPF_0198 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110800856 Common - site-specific recombinase, phage integrase family CPF_0926 151 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110798756 Common - butyryl-CoA dehydrogenase CPF_0092 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110800325 Common uvrC excinuclease ABC subunit C CPF_0341 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 110798814 Pathogen - hypothetical protein CPF_1727 1 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 110801019 Common rpmC ribosomal protein L29 CPF_2706 145 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 110800379 Common - berberine family protein CPF_0408 40 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110801103 Common - aminotransferase, class V CPF_0845 154 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 110799164 Common dnaX DNA polymerase III subunits gamma and tau CPF_0052 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 110801428 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CPF_2991 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 110800912 Common - penicillin-binding protein, 1A family CPF_2218 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 110799867 Common - hypothetical protein CPF_0965 12 COG5412 COG5412, Phage-related protein Function unknown 110799847 Common - hypothetical protein CPF_1515 8 None None None 110800417 Common - DNA-binding response regulator CPF_0115 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110799668 Common msrB methionine sulfoxide reductase B CPF_1860 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110799187 Common - phosphocarrier, HPr family CPF_1923 101 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 110798957 Common - hypothetical protein CPF_1654 1 None None None 110798914 Common - site-specific recombinase, resolvase family CPF_2606 133 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110799061 Common polC DNA polymerase III PolC CPF_1945 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 110800777 Common - lipase/acylhydrolase family protein CPF_2625 10 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110799400 Common - molybdenum cofactor synthesis protein CPF_2343 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 110798977 Common - hypothetical protein CPF_2210 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 110799717 Common - hypothetical protein CPF_0831 34 COG3402 COG3402, Uncharacterized conserved protein Function unknown 110799374 Common - aminotransferase family protein CPF_1623 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110799670 Pathogen - hypothetical protein CPF_0137 1 None None None 110800960 Common - RecT family protein CPF_0939 15 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 110799397 Common - putative spore coat protein CPF_2484 8 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110799954 Common potC spermidine/putrescine ABC transporter, permease protein PotC CPF_2225 173 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110799259 Common - acetyltransferase, GNAT family CPF_0873 85 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110799015 Common - hypothetical protein CPF_2055 33 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110798983 Common - PTS system, IIB component CPF_2968 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 110798570 Common coaD pantetheine-phosphate adenylyltransferase CPF_1982 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 110799390 Common - alpha-glucosidase CPF_2333 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 110800391 Common - licD family protein CPF_0917 17 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 110799944 Common gidB glucose-inhibited division protein B CPF_2989 200 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 110801180 Common - glycosyl hydrolase, family 25 CPF_1521 31 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110800615 Common - hypothetical protein CPF_2432 1 None None None 110799021 Common - putative permease protein CPF_0853 87 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 110799476 Common - hypothetical protein CPF_2387 42 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 110801271 Pathogen - hypothetical protein CPF_2879 1 None None None 110801077 Common - hypothetical protein CPF_0127 118 COG2855 COG2855, Predicted membrane protein Function unknown 110800045 Common clpC negative regulator of genetic competence MecB/ClpC CPF_2751 230 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 110798717 Common lgt prolipoprotein diacylglyceryl transferase CPF_0047 147 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 110799332 Common nrdG anaerobic ribonucleoside-triphosphate reductase activating protein CPF_2826 75 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110800088 Common - hypothetical protein CPF_1283 8 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110798637 Common - hypothetical protein CPF_0638 23 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 110800825 Pathogen - hypothetical protein CPF_0990 1 None None None 110799760 Common - putative PTS system, ascorbate-specific IIB component SgaB CPF_0646 6 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 110800842 Common pabA para-aminobenzoate synthase glutamine amidotransferase, component II CPF_1271 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 110800477 Common - hypothetical protein CPF_0452 6 COG5561 COG5561, Predicted metal-binding protein Function unknown 110800015 Common - hypothetical protein CPF_0456 2 COG1289 COG1289, Predicted membrane protein Function unknown 110799212 Common codA cytosine deaminase CPF_0750 75 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110798962 Common trx thioredoxin CPF_2664 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110800335 Common thiF thiamine biosynthesis protein ThiF CPF_1855 224 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 110799832 Common rbr rubrerythrin CPF_0847 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 110801402 Common - heparinase II/III-like protein CPF_0471 25 None None None 110801156 Common kdpB potassium-transporting ATPase subunit B CPF_1211 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 110800989 Common hsp90 heat shock protein 90 CPF_0417 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 110798626 Common - hydrolase, NUDIX family CPF_1205 42 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110800590 Pathogen - hypothetical protein CPF_0363 2 None None None 110800907 Common - putative iron ABC transporter, permease protein CPF_0441 203 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110798728 Common ppdK pyruvate phosphate dikinase CPF_2268 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 110799178 Common - nitroreductase family protein CPF_1165 81 COG0778 NfnB, Nitroreductase Energy production and conversion 110800252 Common - LD-carboxypeptidase family protein CPF_2777 76 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110799350 Pathogen - hypothetical protein CPF_1838 1 None None None 110800141 Common - transcriptional regulator, GntR family CPF_2745 138 COG2188 PhnF, Transcriptional regulators Transcription 110800344 Pathogen - hypothetical protein CPF_2365 1 None None None 110801024 Common - coproporphyrinogen III oxidase CPF_2293 213 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 110801116 Common - peptidase, M23/M37 family CPF_0191 184 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110799043 Common cbiK sirohydrochlorin cobaltochelatase CPF_1436 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 110801360 Common - hypothetical protein CPF_1942 43 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 110801417 Common - cation-transporting ATPase, P-type CPF_0317 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110799543 Common asnA asparagine synthetase AsnA CPF_2233 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 110799742 Common dnaB replicative DNA helicase CPF_2970 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 110801421 Common - transcriptional regulator, TetR family CPF_0034 156 COG1309 AcrR, Transcriptional regulator Transcription 110800995 Common - stage IV sporulation protein B CPF_2068 18 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110801035 Common - capsular polysaccharide biosynthesis protein CPF_0466 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110800090 Common - kinase, pfkB family CPF_0398 109 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110801244 Common - degV family protein CPF_0030 55 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110800725 Common - hypothetical protein CPF_1072 1 None None None 110799620 Common - peptidase, M50 family CPF_2389 62 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110799790 Pathogen - hypothetical protein CPF_1763 1 None None None 110800733 Common sdhA L-serine dehydratase, iron-sulfur-dependent, alpha subunit CPF_1246 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110799988 Common pyrK dihydroorotate dehydrogenase electron transfer subunit CPF_1383 99 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110799748 Common - hypothetical protein CPF_2858 1 None None None 110799179 Common recJ single-stranded-DNA-specific exonuclease RecJ CPF_2322 198 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110798564 Common - hypothetical protein CPF_0989 14 COG4994 COG4994, Uncharacterized protein conserved in bacteria Function unknown 110800148 Pathogen - hypothetical protein CPF_0143 1 None None None 110799250 Common - hypothetical protein CPF_2548 85 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 110799432 Common - bacterial transferase hexpeptide repeat protein CPF_0470 37 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110800190 Common - PTS system, mannose/fructose/sorbose family, IIA component CPF_0404 10 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 110799529 Common - peptidase, M16 family CPF_2179 199 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110800048 Common gngC endo-beta-galactosidase, GlcNAc-alpha-1,4-Gal-releasing CPF_1119 33 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 110801149 Pathogen - hypothetical protein CPF_0273 1 None None None 110800906 Common - thermophilic metalloprotease family protein CPF_0868 64 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110799536 Common - tetratricopeptide repeat protein CPF_1499 106 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110798741 Common pepD aminoacyl-histidine dipeptidase CPF_2512 63 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110800841 Common folA dihydrofolate reductase CPF_0051 147 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 110799766 Common - mechanosensitive ion channel family protein CPF_0253 209 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110800758 Common cspB protease CspB CPF_2887 57 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110800563 Common - pyridoxamine kinase CPF_2618 88 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 110799153 Common - putative monogalactosyldiacylglycerol synthase CPF_2470 25 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110800896 Common - peptidase family protein CPF_2427 24 COG2234 Iap, Predicted aminopeptidases General function prediction only 110800683 Common glmM phosphoglucosamine mutase CPF_2638 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110801409 Common spoIIAB anti-sigma F factor CPF_2306 26 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 110801363 Common - nucleoside diphosphate kinase CPF_2227 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 110799936 Common - hypothetical protein CPF_1186 12 COG4828 COG4828, Predicted membrane protein Function unknown 110799202 Common - transcriptional regulator, MerR family CPF_1346 5 None None None 110799857 Common - cyclic nucleotide-binding domain protein CPF_2845 97 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110799368 Common - hypothetical protein CPF_1980 32 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 110801145 Common upp uracil phosphoribosyltransferase CPF_2462 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 110799423 Common mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase CPF_1305 94 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 110798828 Common - Ser/Thr protein phosphatase family protein CPF_2418 116 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110799463 Common sspC1 small, acid-soluble spore protein CPF_2321 10 None None None 110799449 Common pepP xaa-pro aminopeptidase CPF_2854 242 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110800474 Common hprK HPr kinase/phosphorylase CPF_1261 77 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 110800707 Pathogen - hypothetical protein CPF_1743 1 None None None 110799622 Pathogen - hypothetical protein CPF_0964 1 None None None 110800210 Common - hypothetical protein CPF_2371 1 COG1714 COG1714, Predicted membrane protein/domain Function unknown 110799071 Common - hypothetical protein CPF_1226 20 COG1289 COG1289, Predicted membrane protein Function unknown 110800901 Pathogen - hypothetical protein CPF_1030 1 None None None 110801430 Pathogen - hypothetical protein CPF_1060 1 None None None 110801420 Common - DedA family protein CPF_0559 124 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110801052 Common folE GTP cyclohydrolase I CPF_1274 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 110799144 Common - rhomboid family protein CPF_1705 160 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110799404 Common ddl D-alanine--D-alanine ligase CPF_0816 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 110799005 Pathogen - hypothetical protein CPF_1185 1 None None None 110799057 Common - putative scdA protein CPF_0777 39 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 110799118 Common argR arginine repressor CPF_0165 40 COG1438 ArgR, Arginine repressor Transcription 110800810 Common - PTS system, mannose/fructose/sorbose family, IIB component CPF_0401 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 110801415 Common - oxidoreductase, FAD-binding CPF_0780 144 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 110800285 Common - putative methyltransferase CPF_2872 131 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 110799907 Common - transcriptional regulator, TetR family CPF_0072 24 COG1309 AcrR, Transcriptional regulator Transcription 110799688 Common - hypothetical protein CPF_0299 9 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 110799813 Common cwlD N-acetylmuramoyl-L-alanine amidase CPF_2676 174 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110799696 Common - 3-methyladenine DNA glycosylase CPF_2901 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 110800690 Common - hypothetical protein CPF_0927 7 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110798608 Common - transcriptional regulator, GntR family/aminotransferase CPF_2212 213 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110801076 Common - PTS system, lactose/cellobiose-specific IIA component CPF_2902 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 110799474 Common - acetyl-CoA acetyltransferase CPF_2460 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110799569 Common gatY tagatose-bisphosphate aldolase CPF_2962 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 110799189 Common - lrgB-like family protein CPF_2236 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 110801345 Common - PRC-barrel domain protein CPF_1933 7 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110801412 Common - putative PTS system, ascorbate-specific IIA component SgaA CPF_0644 40 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 110799034 Common - putative lysine-specific permease CPF_1369 171 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 110798641 Common - sugar ABC transporter, sugar-binding protein CPF_1113 79 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110800860 Pathogen - hypothetical protein CPF_0813 1 None None None 110801316 Pathogen - hypothetical protein CPF_2919 3 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 110799862 Common - [Fe] hydrogenase CPF_0270 29 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110798662 Pathogen - hypothetical protein CPF_0488 1 None None None 110800500 Common rplJ 50S ribosomal protein L10 CPF_2724 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 110799283 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase CPF_1536 148 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110798785 Common colA microbial collagenase CPF_0166 36 COG3291 COG3291, FOG: PKD repeat General function prediction only 110800046 Pathogen - hypothetical protein CPF_1011 2 None None None 110798984 Common purE phosphoribosylaminoimidazole carboxylase, catalytic subunit CPF_0672 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 110801368 Pathogen - hypothetical protein CPF_2353 1 None None None 110798857 Pathogen - acetyltransferase, GNAT family CPF_2221 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110799565 Common - transcriptional regulator, Fur family CPF_1713 180 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110800762 Common cadA cadmium-translocating P-type ATPase CPF_2587 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110801336 Common - putative iron compound ABC transporter, iron compound-binding protein CPF_0223 96 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110800826 Pathogen - hypothetical protein CPF_2746 1 None None None 110799722 Common hslO Hsp33-like chaperonin CPF_2157 134 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 110800852 Common plc phospholipase C CPF_0042 5 None None None 110800653 Common udp uridine phosphorylase CPF_0375 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 110798768 Pathogen - hypothetical protein CPF_0189 1 None None None 110800931 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CPF_1532 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110799459 Common - PTS system, IID component CPF_2966 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 110800111 Common iolE myo-inositol catabolism protein IolE CPF_0086 67 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110798876 Common - oxidoreductase family protein CPF_1455 97 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110800384 Common - sialidase CPF_0985 18 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 110800938 Common smc chromosome segregation protein SMC CPF_1970 209 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110800642 Common - DedA family protein CPF_0457 154 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110801341 Common - glycosyl transferase, WecB/TagA/CpsF family CPF_2125 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 110799522 Common - sensor histidine kinase CPF_1140 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110799480 Common - undecaprenyl pyrophosphate phosphatase CPF_1390 195 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 110798645 Pathogen - hypothetical protein CPF_0348 1 None None None 110800629 Common - hypothetical protein CPF_1488 1 None None None 110798699 Common hisK histidinol-phosphatase CPF_1312 34 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110799330 Common - ABC transporter, permease protein CPF_1480 221 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110800634 Pathogen - hypothetical protein CPF_2511 1 None None None 110799671 Common - hypothetical protein CPF_1196 2 None None None 110801048 Common - putative aminopeptidase 2 CPF_0588 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 110801065 Common - sensor histidine kinase CPF_0116 119 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110800219 Common - ABC transporter, permease/ATP-binding protein CPF_1776 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110799487 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B CPF_2049 109 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 110799456 Common secE preprotein translocase subunit SecE CPF_2728 7 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 110798831 Common - radical SAM domain protein CPF_2388 66 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 110798821 Pathogen - hypothetical protein CPF_1019 1 None None None 110800507 Common - fibronectin-binding protein CPF_2101 89 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 110800465 Common ffh signal recognition particle protein CPF_1967 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 110801332 Common galK galactokinase CPF_1552 106 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 110800401 Common - hypothetical protein CPF_1142 13 COG1285 SapB, Uncharacterized membrane protein Function unknown 110798657 Common - putative lipoprotein CPF_0997 4 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 110800406 Common - sortase family protein CPF_2615 35 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110800868 Common - putative polysaccharide polymerase protein CPF_0915 12 None None None 110801059 Common - histidine decarboxylase, pyruvoyl type CPF_0378 6 None None None 110799793 Common - hypothetical protein CPF_1762 5 COG3402 COG3402, Uncharacterized conserved protein Function unknown 110801124 Common - nucleoside hydrolase, IUNH family CPF_2260 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 110800943 Common - ErfK/YbiS/YcfS/YnhG family protein CPF_1454 12 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110800393 Common - pirin family protein CPF_0792 146 COG1741 COG1741, Pirin-related protein General function prediction only 110799266 Common - hypothetical protein CPF_1871 4 None None None 110801382 Common - hypothetical protein CPF_0655 1 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 110799369 Common - cell wall-associated serine proteinase CPF_1123 67 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110800145 Common pheT phenylalanyl-tRNA synthetase subunit beta CPF_2139 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 110798633 Common psd phosphatidylserine decarboxylase CPF_0033 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 110799784 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase CPF_2202 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 110800819 Common - PhoH family protein CPF_1919 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 110800185 Common - ABC transporter, solute-binding protein CPF_0556 77 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110798677 Pathogen - hypothetical protein CPF_2229 1 None None None 110801322 Common - hypothetical protein CPF_2661 1 None None None 110801157 Common - rubredoxin/rubrerythrin CPF_0681 24 COG1592 COG1592, Rubrerythrin Energy production and conversion 110799887 Pathogen - hypothetical protein CPF_0960 1 None None None 110798874 Common rplM 50S ribosomal protein L13 CPF_2679 221 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 110798576 Common - hypothetical protein CPF_0144 2 None None None 110800016 Common - cell wall binding repeat protein/zinc carboxypeptidase family CPF_0606 9 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110800298 Common - hypothetical protein CPF_1102 2 COG2717 COG2717, Predicted membrane protein Function unknown 110798898 Pathogen - hypothetical protein CPF_2237 1 None None None 110800173 Common - glutathione peroxidase CPF_0904 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 110800529 Common - signal peptidase I CPF_1804 162 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110799829 Common - single-strand DNA binding protein CPF_1921 15 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110799381 Common - MATE efflux family protein CPF_1409 166 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110798941 Common - aminotransferase, class V CPF_1667 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 110799209 Common - hypothetical protein CPF_0883 4 None None None 110799681 Common trmD tRNA (guanine-N(1)-)-methyltransferase CPF_1963 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 110799818 Common - hypothetical protein CPF_0219 23 None None None 110798885 Common pilT twitching motility protein PilT CPF_2020 189 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 110800830 Common - Sua5/YciO/YrdC/YwlC family protein CPF_2464 236 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 110799870 Common - oxidoreductase, Gfo/Idh/MocA family CPF_0088 182 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110798916 Common - hypothetical protein CPF_0151 2 None None None 110799238 Pathogen - hypothetical protein CPF_0495 1 None None None 110799420 Common xerC site-specific tyrosine recombinase XerC CPF_1366 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110799319 Pathogen - collagen triple helix repeat protein CPF_1202 2 None None None 110800620 Common - hypothetical protein CPF_1239 2 COG4127 COG4127, Uncharacterized conserved protein Function unknown 110799873 Pathogen - hypothetical protein CPF_1310 1 None None None 110801294 Common glgB glycogen branching enzyme CPF_1840 154 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 110801287 Common - RNA pseudouridine synthase family protein CPF_1151 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110801394 Common - leucyl aminopeptidase CPF_2824 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 110800336 Common - sodium:alanine symporter family protein CPF_1672 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 110800139 Common - hypothetical protein CPF_2361 22 COG4769 COG4769, Predicted membrane protein Function unknown 110799676 Common tdcB threonine dehydratase, catabolic CPF_1368 232 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110799322 Pathogen - hypothetical protein CPF_1079 1 None None None 110800389 Common - PTS system, lactose/cellobiose-specific IIB component CPF_2493 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 110800790 Common cls cardiolipin synthetase CPF_0748 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110800204 Common fucP L-fucose permease CPF_1052 48 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 110798841 Common priA primosome assembly protein PriA CPF_1998 207 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 110800151 Pathogen - hypothetical protein CPF_2152 1 None None None 110799124 Common accC biotin carboxylase CPF_1330 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 110800526 Common - vanW-like family protein CPF_1520 39 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 110799191 Common tgt queuine tRNA-ribosyltransferase CPF_2201 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 110800975 Common - cell wall surface anchor family protein CPF_2923 80 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 110800113 Common - DNA topoisomerase CPF_2238 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110798682 Common nifU FeS cluster assembly scaffold protein NifU CPF_2038 161 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 110798731 Common - hypothetical protein CPF_2489 11 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 110800428 Common - hypothetical protein CPF_1665 26 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 110801246 Common - chorismate mutase CPF_0691 13 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 110799751 Common - stage III sporulation protein SpoAB CPF_2086 14 None None None 110799411 Pathogen - putative lipoprotein CPF_1035 1 COG5110 RPN1, 26S proteasome regulatory complex component Posttranslational modification, protein turnover, chaperones 110799646 Pathogen - hypothetical protein CPF_0294 1 None None None 110799228 Pathogen - hypothetical protein CPF_0593 3 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 110799311 Common - SagA protein CPF_0274 90 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 110799977 Common - putative ATP-dependent helicase CPF_1408 84 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 110799616 Common - hypothetical protein CPF_2187 96 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 110799345 Common - exonuclease family protein CPF_2409 28 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 110801326 Pathogen - hypothetical protein CPF_0929 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 110799970 Common - metallo-beta-lactamase family protein CPF_1849 117 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 110800879 Common - GTP binding protein CPF_2215 230 COG2262 HflX, GTPases General function prediction only 110800802 Common - putative carbohydrate diacid regulator CPF_0851 46 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 110798904 Common - hypothetical protein CPF_0562 69 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 110799501 Common - hypothetical protein CPF_1244 44 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 110798581 Common rpoD RNA polymerase sigma factor RpoD CPF_2264 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 110801255 Common - PSP1 domain protein CPF_2758 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 110799820 Pathogen - hypothetical protein CPF_1347 1 None None None 110799497 Common - recombination and DNA strand exchange inhibitor protein CPF_2135 201 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110799416 Common - membrane protein, DedA family CPF_1816 21 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110800609 Common - hypothetical protein CPF_0286 1 None None None 110800163 Common thiD phosphomethylpyrimidine kinase CPF_1545 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 110800264 Pathogen - hypothetical protein CPF_1778 1 None None None 110800245 Common - hypothetical protein CPF_1653 7 COG4640 COG4640, Predicted membrane protein Function unknown 110800798 Pathogen - hypothetical protein CPF_0476 1 None None None 110800497 Pathogen - hypothetical protein CPF_1380 1 None None None 110799846 Common - hypothetical protein CPF_2316 5 None None None 110800547 Common - hypothetical protein CPF_2848 5 COG4129 COG4129, Predicted membrane protein Function unknown 110798953 Common - hypothetical protein CPF_1824 1 None None None 110799193 Common - amino acid ABC transporter, ATP-binding protein CPF_0583 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110800973 Common - hypothetical protein CPF_0987 8 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 110799649 Common yhbH hypothetical protein CPF_1540 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 110800759 Common - ABC1 domain protein CPF_2852 188 COG0661 AarF, Predicted unusual protein kinase General function prediction only 110798923 Common - putative citrate transporter CPF_0768 45 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 110800983 Common - capsular polysaccharide biosynthesis protein CPF_0243 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110799957 Common - hypothetical protein CPF_1096 1 None None None 110798987 Common - putative spore coat protein CPF_2486 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110799307 Common - aminotransferase, classes I and II CPF_2163 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110801422 Common rbsK ribokinase CPF_1884 200 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110798918 Common - fibronectin type III domain protein CPF_2129 26 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 110800342 Pathogen - hypothetical protein CPF_1150 1 None None None 110798819 Common engA GTP-binding protein EngA CPF_2008 238 COG1160 COG1160, Predicted GTPases General function prediction only 110800250 Common - hypothetical protein CPF_0667 9 None None None 110800223 Common gap glyceraldehyde-3-phosphate dehydrogenase, type I CPF_1511 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110800161 Common pyrF orotidine 5'-phosphate decarboxylase CPF_1384 72 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 110800023 Common recN DNA repair protein RecN CPF_2069 217 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 110799611 Common dnaJ chaperone protein DnaJ CPF_2289 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110801273 Common - PTS system, mannose/fructose/sorbose family, IID component CPF_0820 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 110801314 Common - hypothetical protein CPF_1020 9 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110800000 Common - hypothetical protein CPF_0242 3 None None None 110801386 Common - HAD hydrolase, IIB family CPF_1821 144 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110798778 Common tilS tRNA(Ile)-lysidine synthetase CPF_2788 209 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110800197 Common eutM ethanolamine utilization protein EutM CPF_0896 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 110799045 Pathogen - hypothetical protein CPF_2286 1 None None None 110800520 Common lgt prolipoprotein diacylglyceryl transferase CPF_2837 159 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 110799736 Common - putative ferrous iron transport protein CPF_1912 50 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 110800998 Common cbiQ cobalt ABC transporter, permease protein CbiQ CPF_0187 77 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110799470 Common murC UDP-N-acetylmuramate--L-alanine ligase CPF_2816 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 110800568 Common - MdsC protein CPF_1410 19 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110800069 Common - spore maturation protein A CPF_2857 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 110798744 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type CPF_2891 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110801265 Pathogen - hypothetical protein CPF_2296 1 None None None 110800596 Common def polypeptide deformylase CPF_1885 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 110799841 Common - YihY family protein CPF_0281 145 COG1295 Rbn, Predicted membrane protein Function unknown 110799545 Common - sensor histidine kinase CPF_2242 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110800277 Common scpA segregation and condensation protein A CPF_2060 145 COG1354 COG1354, Uncharacterized conserved protein Function unknown 110798725 Common - putative cell division ATP-binding protein FtsE CPF_0296 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 110800143 Common noxA nitrate reductase, NADH oxidase subunit CPF_2050 222 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110799980 Pathogen - hypothetical protein CPF_0567 1 None None None 110798629 Common - probable proton-coupled thiamine transporter YuaJ CPF_1622 14 COG3859 COG3859, Predicted membrane protein Function unknown 110800546 Pathogen - hypothetical protein CPF_0271 1 None None None 110799658 Common pnpA polynucleotide phosphorylase/polyadenylase CPF_1934 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 110801260 Common - ABC transporter, permease protein CPF_1737 145 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110800686 Common galT galactose-1-phosphate uridylyltransferase CPF_1553 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 110799655 Common deoB phosphopentomutase CPF_0376 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 110800578 Common rpmJ ribosomal protein L36 CPF_2689 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 110800828 Common treB PTS system, trehalose-specific IIBC component CPF_0541 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110799073 Common - putative resolvase CPF_2603 3 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110801216 Common - putative threonyl-tRNA synthetase/uridine kinase CPF_1554 67 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 110800967 Common - tetratricopeptide repeat protein CPF_1313 7 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 110800330 Common - hypothetical protein CPF_0938 25 COG5377 COG5377, Phage-related protein, predicted endonuclease DNA replication, recombination, and repair 110799928 Common - dnaK family protein CPF_0241 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 110800607 Common - 3D/G5 domain protein CPF_2842 33 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 110800918 Common - putative bacitracin ABC transporter, permease protein CPF_1194 2 None None None 110801353 Common udk uridine kinase CPF_2023 78 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 110800581 Common - ATP-dependent protease CPF_2308 178 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110799609 Pathogen - putative capsular polysaccharide transporter protein CPF_0916 5 None None None 110801131 Common - hypothetical protein CPF_1040 40 COG3382 COG3382, Uncharacterized conserved protein Function unknown 110801150 Common - hypothetical protein CPF_2926 14 None None None 110800991 Common - putative maltose/maltodextrin ABC transporter, permease protein CPF_2651 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110800872 Common - hypothetical protein CPF_1086 3 None None None 110798969 Pathogen - hypothetical protein CPF_1042 1 None None None 110800963 Common - hypothetical protein CPF_0982 3 None None None 110800011 Common - guanylate kinase-like protein CPF_2762 77 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 110799490 Common - NADH-dependent butanol dehydrogenase CPF_0850 170 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 110799989 Common recX recombination regulator RecX CPF_2178 74 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 110799602 Common - aminotransferase, class I/II CPF_0707 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110799253 Common - L-asparaginase CPF_2005 138 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 110799962 Common - FHA domain protein CPF_0338 67 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 110799105 Common minE cell division topological specificity factor MinE CPF_2392 37 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 110799017 Common - UBA/TS-N domain protein CPF_1055 4 None None None 110799085 Common - DHHA1 domain protein CPF_0714 111 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110799715 Common - hypothetical protein CPF_1158 74 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 110800410 Common - cell wall binding repeat domain protein CPF_0550 11 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 110799063 Pathogen - hypothetical protein CPF_1592 1 None None None 110800665 Pathogen - hypothetical protein CPF_0950 1 None None None 110798639 Common - O-methyltransferase family protein CPF_2025 117 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 110800126 Pathogen - hypothetical protein CPF_0057 1 None None None 110800772 Common - transcriptional regulator, MarR family CPF_1082 10 COG1846 MarR, Transcriptional regulators Transcription 110800258 Pathogen - hypothetical protein CPF_2066 1 None None None 110801400 Common - hypothetical protein CPF_1769 1 None None None 110801172 Common - hypothetical protein CPF_0245 1 None None None 110799865 Common - transcriptional regulator, MerR family CPF_0760 16 COG0789 SoxR, Predicted transcriptional regulators Transcription 110799172 Common - hypothetical protein CPF_1724 8 None None None 110799375 Common - radical SAM domain protein CPF_1897 117 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 110799968 Common - FAD-dependent oxidoreductase CPF_2875 119 COG0579 COG0579, Predicted dehydrogenase General function prediction only 110798689 Pathogen - hypothetical protein CPF_1161 1 None None None 110798586 Common cbiO cobalt ABC transporter, ATP-binding protein CPF_0188 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110801007 Common - hypothetical protein CPF_0295 61 COG1284 COG1284, Uncharacterized conserved protein Function unknown 110800656 Common sdhB L-serine dehydratase, iron-sulfur-dependent, beta subunit CPF_2959 83 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110798833 Common nagA N-acetylglucosamine-6-phosphate deacetylase CPF_2434 124 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 110801114 Common - ABC transporter, permease/ATP-binding protein CPF_0217 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110800837 Common - NAD-dependent deacetylase CPF_0249 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 110798960 Common - alpha-galactosidase CPF_0491 44 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 110799163 Common - putative ATP-dependent DNA helicase PcrA CPF_1416 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110800882 Common - hypothetical protein CPF_2133 52 COG1683 COG1683, Uncharacterized conserved protein Function unknown 110800075 Common - hypothetical protein CPF_1167 2 None None None 110799240 Pathogen - hypothetical protein CPF_1001 1 None None None 110799232 Common coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase CPF_1999 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 110799028 Common - conserved hypothetical protein subfamily CPF_0180 30 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 110800630 Common - putative ABC transporter, permease protein CPF_0704 49 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 110801086 Common yajC preprotein translocase subunit YajC CPF_2200 33 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 110799032 Common - lipoprotein, BMP family CPF_1832 88 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110799026 Common - beta-galactosidase CPF_0766 62 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 110800307 Common - iron chelate uptake ABC transporter, FeCT family, ATP-binding protein CPF_1298 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110799218 Common - BNR/Asp-box repeat domain protein CPF_1759 3 None None None 110801234 Common - hypothetical protein CPF_1774 1 None None None 110800376 Common - hypothetical protein CPF_2760 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 110800786 Common - stage III sporulation protein AA CPF_2087 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 110799672 Common - competence family protein CPF_2301 107 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 110799162 Common - oxidoreductase, pyridine nucleotide-disulphide family CPF_2874 179 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110799797 Common - hypothetical protein CPF_1696 14 None None None 110801399 Common - antioxidant, AhpC/TSA family CPF_0261 224 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110798610 Common - hypothetical protein CPF_0800 140 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 110799807 Common - acetyltransferase, GNAT family CPF_1059 63 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110800097 Common - putative ferredoxin CPF_2757 195 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110799592 Common - sensor histidine kinase CPF_2181 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110801027 Common deoD purine nucleoside phosphorylase CPF_1652 101 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 110800318 Common - putative penicillin-binding protein CPF_2395 191 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110798802 Pathogen - hypothetical protein CPF_0032 1 None None None 110799641 Pathogen - hypothetical protein CPF_1169 1 None None None 110798595 Common - peptidase, M23/M37 family protein CPF_1867 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110799211 Common - hypothetical protein CPF_0970 1 None None None 110801102 Common kduI 5-keto-4-deoxyuronate isomerase CPF_0395 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 110799792 Common - iron-sulfur cluster-binding protein CPF_0560 105 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 110798812 Common - ABC transporter, permease protein CPF_0879 3 None None None 110801010 Common - chromate transport protein CPF_2508 56 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 110799787 Common - hypothetical protein CPF_2911 1 None None None 110800597 Pathogen - hypothetical protein CPF_0846 1 None None None 110800747 Common - phage tail tape measure protein, TP901 family CPF_1576 41 COG5412 COG5412, Phage-related protein Function unknown 110799934 Common hsdM type I restriction-modification system, M subunit CPF_2599 162 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 110800108 Common cspC serine protease C CPF_2886 6 None None None 110800925 Common hsdR type I restriction-modification system, R subunit CPF_2596 143 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 110800328 Common - single-strand DNA-binding protein CPF_2166 9 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110798891 Common - putative cation transporter CPF_2767 130 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 110800490 Common - putative lipase CPF_0304 56 COG0657 Aes, Esterase/lipase Lipid metabolism 110799285 Common - hypothetical protein CPF_0010 5 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 110800355 Common lctP L-lactate permease CPF_0307 104 COG1620 LldP, L-lactate permease Energy production and conversion 110800646 Common - putative ferredoxin CPF_2834 40 COG1141 Fer, Ferredoxin Energy production and conversion 110800349 Common thiE thiamine-phosphate pyrophosphorylase CPF_1543 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110800228 Common - hypothetical protein CPF_1926 92 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110800267 Pathogen - hypothetical protein CPF_0391 1 None None None 110800958 Common rpsU 30S ribosomal protein S21 CPF_2280 112 None None None 110798809 Common spoIID stage II sporulation protein D CPF_2448 40 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 110800370 Common - PTS system, IIC component CPF_2967 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 110799320 Common - UDP-glucose/GDP-mannose dehydrogenase family CPF_0468 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 110799344 Common - LD-carboxypeptidase family protein CPF_2768 86 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110801191 Common - molybdopterin oxidoreductase CPF_1799 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110798753 Common - putative phage tail component CPF_1575 7 COG4722 COG4722, Phage-related protein Function unknown 110800321 Common rplC 50S ribosomal protein L3 CPF_2714 246 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 110800640 Common - amino acid permease family protein CPF_1400 86 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110800306 Common - GGDEF domain protein CPF_2043 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110800233 Common - degV family protein CPF_1517 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 110800444 Common - flavodoxin CPF_2319 24 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 110800365 Common - putative deoxyribonucleotide triphosphate pyrophosphatase CPF_2535 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 110800292 Common - transcriptional regulator, GntR family/aminotransferase CPF_0356 189 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110800029 Common - endonuclease/exonuclease/phosphatase family protein CPF_0423 5 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 110800053 Common spoVB stage V sporulation protein B CPF_1413 45 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110801366 Common - hypothetical protein CPF_1899 2 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 110800056 Common - hypothetical protein CPF_0743 5 None None None 110799068 Common - electron transport complex, RnfABCDGE type, C subunit CPF_1663 81 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 110800084 Common - HesB-like domain protein CPF_0132 4 COG0316 IscA, Uncharacterized conserved protein Function unknown 110799116 Pathogen - hypothetical protein CPF_0686 1 None None None 110798932 Common - hypothetical protein CPF_1012 3 COG4371 COG4371, Predicted membrane protein Function unknown 110800206 Common - PTS system, L-Ascorbate family, IIA component CPF_0501 66 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 110801206 Common - two component regulator three Y motif protein CPF_2547 2 None None None 110799991 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein CPF_2266 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 110799465 Common - rubredoxin CPF_0782 122 COG1773 COG1773, Rubredoxin Energy production and conversion 110799339 Common mgsA methylglyoxal synthase CPF_1265 87 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 110798794 Common - rhodanese domain protein CPF_1837 171 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110799549 Pathogen - putative lipoprotein CPF_1353 1 None None None 110799830 Common cobQ cobyric acid synthase CobQ CPF_1300 157 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 110799590 Common prfA peptide chain release factor 1 CPF_2466 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 110801223 Pathogen - hypothetical protein CPF_0015 1 COG2433 COG2433, Uncharacterized conserved protein Function unknown 110798990 Common - hypothetical protein CPF_1771 1 None None None 110798862 Common feoB ferrous iron transport protein B CPF_1009 171 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 110800457 Common folD folD bifunctional protein CPF_2077 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 110800976 Common - pyruvate kinase barrel domain protein CPF_1281 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110799479 Common - putative L-xylulose 5-phosphate 3-epimerase CPF_0649 29 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 110801250 Common - putative endoribonuclease L-PSP CPF_1267 195 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110799003 Common thiH thiamine biosynthesis protein ThiH CPF_0106 61 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 110800398 Common - glycosyl transferase, group 2 family protein CPF_0596 31 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 110799342 Common - putative phage head-tail adaptor CPF_1582 1 None None None 110799698 Common - hypothetical protein CPF_2364 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110799036 Common - CAAX amino terminal protease family protein CPF_1850 5 None None None 110801229 Common - serine protease CPF_2494 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110798643 Common eutA reactivating factor for ethanolamine ammonia lyase CPF_0890 17 COG4819 EutA, Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition Amino acid transport and metabolism 110799567 Common narB nitrate reductase electron transfer subunit CPF_2051 156 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 110800731 Common - lrgA family protein CPF_2235 41 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 110800862 Common - putative peptidase CPF_2447 163 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110798686 Pathogen - hypothetical protein CPF_0867 1 None None None 110801343 Common - putative transketolase, C-terminal subunit CPF_0293 231 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 110801193 Common - sensory box histidine kinase CPF_1243 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110799563 Common pstS phosphate ABC transporter, phosphate-binding protein CPF_0618 209 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 110798647 Common hbd 3-hydroxybutyryl-CoA dehydrogenase CPF_2581 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110799763 Common - NADPH-dependent FMN reductase CPF_0909 42 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 110799946 Pathogen - hypothetical protein CPF_0921 2 None None None 110800769 Common accA acetyl-CoA carboxylase, carboxyl transferase, alpha subunit CPF_1332 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 110801347 Common - sensory box histidine kinase CPF_2010 226 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110799815 Common - 3D/G5 domain protein CPF_1755 29 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 110798660 Pathogen - hypothetical protein CPF_2230 1 None None None 110799472 Common - calx-beta domain protein CPF_2130 41 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 110799221 Common kduD 2-deoxy-D-gluconate 3-dehydrogenase CPF_0396 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110799644 Pathogen - hypothetical protein CPF_2095 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110799720 Common - hypothetical protein CPF_2057 1 None None None 110799924 Common - putative phytase CPF_1775 7 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 110798887 Common - hypothetical protein CPF_2450 1 None None None 110800040 Common - pullulanase family protein CPF_1087 176 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 110800932 Common - hypothetical protein CPF_0314 9 None None None 110800651 Common - putative phage infection protein CPF_2916 59 COG1511 COG1511, Predicted membrane protein Function unknown 110801092 Common - putative D-lactate dehydrogenase CPF_0510 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110800455 Common rpsE 30S ribosomal protein S5 CPF_2697 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 110799557 Common - putative alpha-N-acetylgalactosaminidase CPF_1472 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110800850 Pathogen - hypothetical protein CPF_1108 1 None None None 110800859 Common rfbD dTDP-4-dehydrorhamnose reductase CPF_0599 188 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 110799273 Common - ABC transporter, ATP-binding protein CPF_1199 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110798766 Common - radical SAM domain protein CPF_1251 58 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 110798659 Common - AP endonuclease, family 2 CPF_1335 50 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 110798823 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CPF_2182 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110800509 Common - anaerobic sulfite reductase, C subunit CPF_1787 78 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110799485 Common - voltage-gated chloride channel family protein CPF_2173 165 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110801099 Common - hypothetical protein CPF_0322 44 COG1808 COG1808, Predicted membrane protein Function unknown 110800403 Common - Na/Pi-cotransporter family protein/PhoU family protein CPF_2677 122 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 110801307 Common - hypothetical protein CPF_1109 3 None None None 110800467 Common - hypothetical protein CPF_1580 1 None None None 110799454 Common rplN 50S ribosomal protein L14 CPF_2704 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 110799050 Common - aminotransferase, DegT/DnrJ/EryC1/StrS family CPF_0911 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 110800130 Pathogen - putative preprotein translocase subunit CPF_2964 1 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 110800395 Common - hypothetical protein CPF_0415 12 COG4905 COG4905, Predicted membrane protein Function unknown 110800565 Pathogen - hypothetical protein CPF_0475 1 None None None 110800283 Common - acetyltransferase, GNAT family CPF_0436 2 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110800064 Common spoVAC stage V sporulation protein AC CPF_2304 15 None None None 110799728 Common - phosphofructokinase family protein CPF_1389 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110799366 Common - pentapeptide repeat protein CPF_1207 65 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110801147 Common eutL ethanolamine utilization protein EutL CPF_0893 15 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 110801217 Common - hypothetical protein CPF_1407 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 110799520 Common gapN glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent CPF_2748 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110799200 Common - hypothetical protein CPF_2346 3 COG5578 COG5578, Predicted integral membrane protein Function unknown 110801407 Common pepD aminoacyl-histidine dipeptidase CPF_2403 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110801143 Pathogen - gram positive anchor protein CPF_2545 1 None None None 110799527 Common - phosphate transporter family protein CPF_0563 170 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 110800908 Common - hypothetical protein CPF_1163 1 None None None 110799624 Common - hypothetical protein CPF_0039 8 None None None 110800552 Common - putative tryptophan transport protein CPF_1504 6 None None None 110798970 Common rplP 50S ribosomal protein L16 CPF_2707 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 110799822 Common - amidohydrolase domain protein CPF_1475 175 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110799429 Common - hypothetical protein CPF_1460 30 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110798926 Common - putative neutral zinc metallopeptidase CPF_1995 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 110800241 Common - acetyltransferase, GNAT family CPF_0849 98 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110799059 Common - V-type ATP synthase subunit K CPF_1894 33 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 110799169 Common metC cystathionine beta-lyase CPF_0169 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110799691 Common ftsZ cell division protein FtsZ CPF_2018 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 110798569 Pathogen - hypothetical protein CPF_1124 1 None None None 110800812 Pathogen - hypothetical protein CPF_2851 1 None None None 110798591 Common - putative lactoylglutathione lyase CPF_0449 129 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110799707 Common selB selenocysteine-specific translation elongation factor CPF_2372 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 110798979 Common - hypothetical protein CPF_1493 13 COG1289 COG1289, Predicted membrane protein Function unknown 110798605 Common - hypothetical protein CPF_0247 5 None None None 110800246 Common - hypothetical protein CPF_1815 1 None None None 110798669 Common accD acetyl-CoA carboxylase, carboxyl transferase, beta subunit CPF_1331 220 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 110800713 Common modB molybdate ABC transporter, permease protein CPF_2341 172 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 110800584 Common hemD uroporphyrinogen-III methyltransferase/synthase CPF_1687 200 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 110798783 Common - hydrolase, NUDIX family CPF_2150 122 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110799430 Common spo0A Spo0A protein CPF_2067 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110799634 Common - V-type ATP synthase subunit D CPF_1888 45 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 110801432 Common - putative aldose 1-epimerase CPF_0279 45 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 110800502 Common - EAL domain protein CPF_0908 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110799112 Common - hypothetical protein CPF_1089 11 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110798948 Common asnC asparaginyl-tRNA synthetase CPF_2823 221 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110799538 Common - GGDEF domain protein CPF_1220 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110800756 Common rpsN 30S ribosomal protein S14 CPF_2701 186 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 110799550 Common - hypothetical protein CPF_2849 9 COG4129 COG4129, Predicted membrane protein Function unknown 110799581 Common - putative cytochrome C-type biogenesis protein CPF_0739 195 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 110801231 Common - glycosyl hydrolase, family 38 CPF_0848 53 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 110798993 Common serS seryl-tRNA synthetase CPF_0014 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 110800688 Common - phage major tail protein, phi13 family CPF_1579 7 None None None 110800524 Common - MazG family protein CPF_2803 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 110800368 Common - putative ABC transporter, permease protein CPF_0119 20 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110798737 Common - putative lipoprotein CPF_1080 6 None None None 110800704 Common - ABC transporter, permease/ATP-binding protein CPF_0216 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 110798748 Common rimI ribosomal-protein-alanine acetyltransferase CPF_2424 197 COG0456 RimI, Acetyltransferases General function prediction only 110799888 Common - ybaK/prolyl-tRNA synthetases associated domain protein CPF_1609 88 COG2606 EbsC, Uncharacterized conserved protein Function unknown 110799126 Common - deoxyguanosine kinase/deoxyadenosine kinase CPF_0067 40 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 110800874 Common pyrG CTP synthetase CPF_2472 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 110801074 Common - oxidoreductase, short chain dehydrogenase/reductase family CPF_0353 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110801182 Common - sortase family protein CPF_0773 22 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110801248 Common - hypothetical protein CPF_2186 29 COG3610 COG3610, Uncharacterized conserved protein Function unknown 110799150 Common trpS tryptophanyl-tRNA synthetase CPF_0614 228 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110799975 Common - ABC transporter, ATP-binding protein CPF_0703 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 110799298 Common - putative alginate biosynthesis protein AlgI CPF_1766 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 110799758 Common - aminopeptidase CPF_2253 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110800705 Common - conserved hypothetical protein TIGR00159 CPF_2660 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 110800073 Common - putative helicase CPF_1148 146 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 110799109 Common - hydrolase, TatD family CPF_2843 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 110799329 Common - rubredoxin CPF_0779 118 COG1773 COG1773, Rubredoxin Energy production and conversion 110800426 Common - major facilitator family transporter CPF_0065 120 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 110799879 Common - hypothetical protein CPF_1088 2 None None None 110799380 Common dprA DNA protecting protein DprA CPF_1957 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 110799303 Common - hypothetical protein CPF_1941 19 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 110800618 Common - peptidase, S41 family CPF_1495 9 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110800723 Common - hypothetical protein CPF_0980 22 COG4283 COG4283, Uncharacterized conserved protein Function unknown 110799469 Common purB adenylosuccinate lyase CPF_1922 185 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 110798680 Common - hypothetical protein CPF_0627 11 None None None 110800632 Common - ethanolamine utilization protein EutN CPF_0900 27 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 110799848 Common - hypothetical protein CPF_0680 43 COG3304 COG3304, Predicted membrane protein Function unknown 110801046 Common birA BirA bifunctional protein CPF_0664 208 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 110801380 Common rpsM 30S ribosomal protein S13 CPF_2688 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 110800603 Common - putative transporter CPF_0036 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 110800796 Common rpmG 50S ribosomal protein L33 CPF_2729 85 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 110801324 Common - hypothetical protein CPF_2639 62 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110800165 Common - putative symporter YidK CPF_0087 131 COG4146 COG4146, Predicted symporter General function prediction only 110800382 Common - hypothetical protein CPF_0053 64 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 110800337 Common rpsB 30S ribosomal protein S2 CPF_1954 231 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 110800217 Common - putative permease CPF_0045 88 COG0701 COG0701, Predicted permeases General function prediction only 110799882 Common - DhaG protein CPF_1179 40 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 110801177 Common - amidohydrolase family protein CPF_1287 172 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110799686 Common - thiamine pyrophosphokinase CPF_1988 54 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 110799413 Pathogen - hypothetical protein CPF_0967 1 None None None 110799052 Common - HAD hydrolase, IIB family CPF_0590 151 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110800952 Common - 4Fe-4S binding domain protein/radical SAM domain protein CPF_0641 78 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 110800600 Common - putative RNA polymerase sigma factor CPF_0484 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110798810 Common - hypothetical protein CPF_2838 1 None None None 110799850 Pathogen - hypothetical protein CPF_1640 1 None None None 110799134 Pathogen - hypothetical protein CPF_1600 1 None None None 110798630 Pathogen - TPR domain protein CPF_1215 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110801293 Common - putative phage terminase, small subunit CPF_1588 6 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 110798690 Common - radical SAM domain protein CPF_2258 4 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 110800361 Common - putative maltose/maltodextrin ABC transporter, permease protein CPF_2650 154 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 110801320 Common - pyridine nucleotide-disulphide oxidoreductase family protein CPF_1197 147 COG2081 COG2081, Predicted flavoproteins General function prediction only 110800018 Pathogen - hypothetical protein CPF_2294 1 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 110799875 Common - sortase family protein CPF_0212 32 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110798648 Pathogen - hypothetical protein CPF_1651 1 None None None 110800626 Pathogen - putative lioprotein CPF_0346 2 None None None 110801122 Common - uracil transporter CPF_1756 134 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110800627 Common - acyltransferase family protein CPF_1110 20 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 110800945 Common - ABC transporter, permease/ATP-binding protein CPF_1777 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110798713 Common - putative spore-cortex-lytic enzyme CPF_2662 29 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 110800848 Common - UDP-N-acetylmuramyl tripeptide synthetase MurC-like protein CPF_1392 47 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110799268 Common - transcriptional regulator, LysR family CPF_1726 193 COG0583 LysR, Transcriptional regulator Transcription 110799859 Common - conserved hypothetical protein TIGR00266 CPF_0318 76 COG2013 COG2013, Uncharacterized conserved protein Function unknown 110800273 Pathogen - hypothetical protein CPF_0533 1 None None None 110799525 Common - propionate CoA-transferase CPF_0091 98 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 110800175 Common - cobalt ABC transporter, permease protein CPF_2681 77 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110799779 Pathogen - hypothetical protein CPF_1657 1 None None None 110798796 Common - DNA-binding response regulator CPF_1192 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110798716 Common - peptidase T-like protein CPF_2778 91 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 110801356 Pathogen - hypothetical protein CPF_0708 1 None None None 110801392 Common - hypothetical protein CPF_0333 2 None None None 110799231 Common ahpC alkyl hydroperoxide reductase, C subunit CPF_0784 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110800387 Common - putative transcriptional regulatory protein CPF_1887 9 COG4189 COG4189, Predicted transcriptional regulator Transcription 110801084 Common - amino acid permease family protein CPF_0730 56 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 110799447 Common thiM hydroxyethylthiazole kinase CPF_1544 76 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 110799902 Common - molybdopterin-guanine dinucleotide biosynthesis protein CPF_2047 116 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 110798614 Common - putative sporulation protein CPF_2064 14 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 110800531 Pathogen - hypothetical protein CPF_2092 1 None None None 110800119 Common rpsH 30S ribosomal protein S8 CPF_2700 219 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 110800916 Common - transglycosylase, SLT family CPF_2248 167 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110800774 Common - HAD hydrolase, IIB family CPF_0504 85 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110800969 Common - putative galactoside ABC transporter, galactoside-binding protein CPF_1548 97 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110799174 Common sfsA sugar fermentation stimulation protein A CPF_0574 108 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 110800183 Common - 3D domain protein CPF_1437 83 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 110799656 Pathogen - hypothetical protein CPF_0615 1 None None None 110798701 Common pfkA 6-phosphofructokinase CPF_0350 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110799371 Common - hypothetical protein CPF_1749 19 COG4708 COG4708, Predicted membrane protein Function unknown 110800332 Common - transcriptional regulator, DeoR family CPF_0642 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110800256 Common - transcriptional regulator, GntR family CPF_2589 12 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 110800294 Pathogen - hypothetical protein CPF_0860 1 None None None 110799255 Common - relA/spoT family protein CPF_0635 84 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 110800544 Common asp alkaline shock protein CPF_2079 39 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 110800692 Common - carboxyl-terminal protease CPF_0298 187 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110799653 Common - amidohydrolase family protein CPF_1415 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110800965 Pathogen - hypothetical protein CPF_1596 1 None None None 110800768 Pathogen - hypothetical protein CPF_1779 1 None None None 110800721 Common - hypothetical protein CPF_2011 163 COG1496 COG1496, Uncharacterized conserved protein Function unknown 110800078 Common - radical SAM domain protein CPF_2198 113 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 110799743 Common - sugar ABC transporter, permease protein CPF_1114 171 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110799780 Common vhb bacterial hemoglobin CPF_2209 77 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 110798843 Common - putative ferrichrome ABC transporter, ATP-binding protein CPF_0810 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110800013 Common - amino acid permease family protein CPF_2332 58 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110801152 Common - hypothetical protein CPF_0762 14 None None None 110799916 Common fabZ beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ CPF_1329 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 110799019 Common - hypothetical protein CPF_1904 5 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110798910 Common - stage III sporulation protein AG CPF_2081 15 None None None 110800619 Common cysK cysteine synthase A CPF_1529 223 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 110799868 Pathogen - hypothetical protein CPF_2354 1 None None None 110799755 Common - DAK2 domain protein CPF_1985 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 110798938 Common soj sporulation initiation inhibitor protein soj CPF_2988 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110799891 Common - pyridine nucleotide-disulphide oxidoreductase family protein CPF_0785 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110799718 Common - sortase family protein CPF_0124 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 110798730 Common - hypothetical protein CPF_0640 14 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 110799391 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 CPF_2313 22 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110800128 Common - hypothetical protein CPF_2275 200 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 110799948 Common - helicase domain protein CPF_2359 98 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110801184 Common - ABC transporter, substrate-binding protein CPF_2413 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 110800663 Common - ABC transporter, ATP-binding protein CPF_0745 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110799378 Common deoC deoxyribose-phosphate aldolase CPF_2309 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 110801136 Pathogen - hypothetical protein CPF_1000 1 None None None 110800527 Common - coenzyme B12-dependent glycerol dehydratase, medium subunit CPF_1174 13 None None None 110800985 Common - alpha/beta hydrolase fold family protein CPF_0740 126 COG0657 Aes, Esterase/lipase Lipid metabolism 110799904 Common - MutT/nudix family protein CPF_2957 22 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110801330 Common - hypothetical protein CPF_2537 2 None None None 110799795 Common - glycosyl hydrolase, family 65 CPF_1117 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 110798723 Common adh1 NADPH-dependent butanol dehydrogenase CPF_1465 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110801275 Pathogen - hypothetical protein CPF_1098 1 None None None 110799024 Common - transcriptional regulator, PadR family CPF_2348 25 COG1695 COG1695, Predicted transcriptional regulators Transcription 110799396 Common - V-type ATP synthase subunit C CPF_1892 25 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 110800911 Common - sulfatase family protein CPF_1101 89 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110800594 Common - DedA family protein CPF_0316 133 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110800511 Common murI glutamate racemase CPF_2893 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 110798679 Common rnc ribonuclease III CPF_1972 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 110799809 Common - toxin secretion/phage lysis holin CPF_0370 12 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 110799921 Common - putative D-3-phosphoglycerate dehydrogenase CPF_0061 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110798872 Common - histidinol phosphate phosphatase, HisJ family CPF_1620 20 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 110800221 Common - metallopeptidase, family M24 CPF_2820 245 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110801424 Common recQ ATP-dependent DNA helicase RecQ CPF_1542 218 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 110798866 Common - putative pilus biogenesis protein CPF_2097 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 110799939 Common - hypothetical protein CPF_1790 1 None None None 110800309 Common - hydrolase, NUDIX family CPF_0575 85 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 110799135 Common nrdD anaerobic ribonucleoside-triphosphate reductase CPF_0922 105 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 110801434 Common - hydrolase, NUDIX family CPF_2065 127 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110801067 Common - putative penicillin-binding protein CPF_0340 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110800195 Common - OB-fold nucleic acid binding domain protein CPF_1618 33 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 110800208 Common spoVD stage V sporulation protein D CPF_2117 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110799224 Common punA purine nucleoside phosphorylase CPF_2818 146 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110799982 Common pulA pullulanase, type I CPF_1803 157 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 110801060 Common rpmB ribosomal protein L28 CPF_1987 54 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 110800744 Common hsdS type I restriction-modification enzyme, S subunit CPF_2598 104 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 110800463 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CPF_0582 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110798817 Common - methyltransferase, HemK family CPF_2467 215 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 110800340 Pathogen - putative type IV pilin CPF_2572 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 110799047 Common hemA glutamyl-tRNA reductase CPF_1690 176 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 110799950 Common - hypothetical protein CPF_1668 14 COG4492 PheB, ACT domain-containing protein General function prediction only 110799195 Common purA adenylosuccinate synthetase CPF_2958 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 110799358 Common - sporulation sigma factor SigK CPF_2021 212 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 110799570 Common - RNA polymerase sigma-70 factor CPF_0539 145 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110800737 Pathogen - hypothetical protein CPF_2459 1 None None None 110800279 Pathogen - hypothetical protein CPF_2924 1 None None None 110799984 Common - hemolysin III CPF_1725 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 110801267 Common nrdF ribonucleotide-diphosphate reductase subunit beta CPF_2670 160 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 110799843 Common - hypothetical protein CPF_1257 32 COG5483 COG5483, Uncharacterized conserved protein Function unknown 110800372 Common - FMN-dependent dehydrogenase CPF_2132 158 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 110798617 Common - N-6 DNA methylase CPF_2914 13 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 110798670 Common - cell cycle protein, FtsW/RodA/SpoVE family CPF_0339 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110800339 Common - type IV pilus assembly protein PilM CPF_2565 65 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 110799184 Common xseB exodeoxyribonuclease VII small subunit CPF_2075 20 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 110800231 Common - iron(III) ABC transporter, ATP-binding protein CPF_1424 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110799667 Common - stage III sporulation protein AD CPF_2084 15 None None None 110799337 Common pgi glucose-6-phosphate isomerase CPF_2549 203 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 110799097 Pathogen - hypothetical protein CPF_1204 1 None None None 110799467 Common - conserved hypothetical protein TIGR00275 CPF_2952 146 COG2081 COG2081, Predicted flavoproteins General function prediction only 110801160 Common - hypothetical protein CPF_1843 24 COG3610 COG3610, Uncharacterized conserved protein Function unknown 110801305 Common - glycosyl hydrolase, family 1 CPF_2609 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 110798967 Common - hypothetical protein CPF_1133 3 None None None 110799009 Pathogen - hypothetical protein CPF_0647 2 None None None 110800133 Common - signal peptidase I CPF_2579 35 None None None 110800514 Common - ABC transporter, ATP-binding protein CPF_0175 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 110798776 Common - acetyltransferase, GNAT family CPF_1085 23 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110799349 Pathogen - hypothetical protein CPF_0874 1 None None None 110801312 Common - esterase-like protein CPF_1833 42 COG0657 Aes, Esterase/lipase Lipid metabolism 110798980 Common - hypothetical protein CPF_1315 1 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110801033 Common - hypothetical protein CPF_0821 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 110800054 Common ftsK DNA translocase FtsK CPF_1930 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 110800449 Common - hypothetical protein CPF_0798 4 None None None 110800086 Common uvsE putative UV damage endonuclease CPF_2329 27 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 110800051 Common - hypothetical protein CPF_0832 6 COG3428 COG3428, Predicted membrane protein Function unknown 110800745 Common - hypothetical protein CPF_2635 1 None None None 110799503 Common asd aspartate-semialdehyde dehydrogenase CPF_2160 230 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 110801208 Pathogen - hypothetical protein CPF_0461 1 None None None 110799993 Common - DNA polymerase III subunit epsilon CPF_1655 116 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 110799103 Common - PTS system, sucrose-specific IIBC component CPF_1785 44 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 110800442 Common - hypothetical protein CPF_0656 2 None None None 110800154 Common atpC ATP synthase F1, epsilon subunit CPF_2451 133 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 110799577 Common - putative peptidase CPF_1656 81 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 110801009 Common - hypothetical protein CPF_1411 6 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110799087 Common - hypothetical protein CPF_1859 1 None None None 110799773 Common - kinase, pfkB family CPF_1733 126 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110799216 Common secF preprotein translocase subunit SecF CPF_2196 219 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 110799444 Common - putative cell division protein FtsL CPF_2118 1 None None None 110798864 Common rpsI 30S ribosomal protein S9 CPF_2678 246 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 110800685 Common - hypothetical protein CPF_2169 191 COG0628 PerM, Predicted permease General function prediction only 110798925 Pathogen - putative lipoprotein CPF_1500 1 None None None 110799599 Common - hypothetical protein CPF_2003 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 110800412 Common ssb single-strand binding protein CPF_2977 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110799604 Common ychF translation-associated GTPase CPF_2121 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 110799460 Common - ethanolamine utilization protein EutQ CPF_0903 18 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 110801220 Common rplS 50S ribosomal protein L19 CPF_1962 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 110799597 Pathogen - hypothetical protein CPF_0121 1 None None None 110798759 Common - V-type ATP synthase subunit A CPF_1890 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 110799387 Common mreB rod shape-determining protein MreB CPF_2398 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 110798588 Common - transcriptional regulator, MarR family CPF_1208 114 COG1846 MarR, Transcriptional regulators Transcription 110799995 Common selA selenocysteine synthase CPF_2373 73 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 110801221 Common - nitroreductase family protein CPF_1135 50 COG0778 NfnB, Nitroreductase Energy production and conversion 110800262 Common - hypothetical protein CPF_1162 5 None None None 110800679 Common spoVD stage V sporulation protein D CPF_0544 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110799955 Common - hypothetical protein CPF_0256 5 None None None 110799327 Common pyk pyruvate kinase CPF_0351 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110800835 Common - hypothetical protein CPF_0803 34 COG3681 COG3681, Uncharacterized conserved protein Function unknown 110800311 Common - hypothetical protein CPF_0105 1 None None None 110800884 Common - glycosyl transferase, group 2 family protein CPF_2328 122 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110799305 Common eno phosphopyruvate hydratase CPF_1505 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 110800783 Common - stress responsive A/B barrel domain protein CPF_0844 31 None None None 110799249 Common - putative resolvase CPF_1608 129 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110799160 Common - PTS system, mannose/fructose/sorbose family, IIC component CPF_0819 30 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 110800025 Common - hypothetical protein CPF_0462 30 COG1289 COG1289, Predicted membrane protein Function unknown 110800121 Common - hypothetical protein CPF_1290 1 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 110801072 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase CPF_2774 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 110801104 Common - conserved hypothetical protein TIGR00257 CPF_2211 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 110800177 Common - putative lipoprotein CPF_2931 9 COG5401 COG5401, Spore germination protein General function prediction only 110798800 Common argH argininosuccinate lyase CPF_0682 233 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110799141 Common - hypothetical protein CPF_2473 14 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 110799518 Common - PTS system, IIC component CPF_1715 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 110798807 Pathogen - hypothetical protein CPF_0858 1 None None None 110799234 Common rplU 50S ribosomal protein L21 CPF_2385 199 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 110799242 Common - putative iron chelate uptake ABC transporter, solute-binding protein CPF_0213 115 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110800170 Common - S4 domain protein CPF_2106 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 110799151 Common - hypothetical protein CPF_2975 1 None None None 110801210 Common valS valyl-tRNA synthetase CPF_2175 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110801397 Common lexA LexA repressor CPF_1364 175 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 110800660 Common - cysteine desulfurase family protein CPF_2983 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110798593 Common lacZ beta-galactosidase CPF_1474 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 110800675 Common purF amidophosphoribosyltransferase CPF_0674 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 110801029 Common - ethanolamine utilization protein CPF_0901 17 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 110799802 Common - hypothetical protein CPF_1401 20 COG2389 COG2389, Uncharacterized metal-binding protein General function prediction only 110800032 Common ftsH ATP-dependent metalloprotease FtsH CPF_0579 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 110799674 Common - transcriptional regulator, LacI family CPF_2649 129 COG1609 PurR, Transcriptional regulators Transcription 110800923 Common - Fic family protein CPF_0838 69 COG3177 COG3177, Uncharacterized conserved protein Function unknown 110799495 Common - putative hydrolase CPF_2276 57 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 110801257 Pathogen - hypothetical protein CPF_2443 1 None None None 110800347 Pathogen - hypothetical protein CPF_2880 1 None None None 110798931 Common - DNA-binding protein CPF_2889 7 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 110800300 Common virI DNA-binding response regulator CPF_2356 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110800002 Pathogen - hypothetical protein CPF_0828 1 None None None 110800181 Common - TrkA domain protein CPF_0520 6 None None None 110798751 Common - glycosyl hydrolase, family 13 CPF_0802 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110798855 Common - choline/ethanolamine kinase family protein CPF_1288 16 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110800482 Common - DNA-binding response regulator, AraC family CPF_2344 226 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110799839 Common - hypothetical protein CPF_1270 128 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110801384 Common yunB sporulation protein YunB CPF_2217 14 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 110800553 Common - [Fe] hydrogenase CPF_2900 29 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 110798955 Common gltA putative oxidoreductase CPF_1463 186 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110799761 Common - putative FAD dependent oxidoreductase CPF_2054 16 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 110799799 Common recG ATP-dependent DNA helicase RecG CPF_1984 226 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 110799080 Common - HAD hydrolase, IIB family CPF_0719 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110798853 Common - PTS system, IID component CPF_1714 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 110798574 Common adhE aldehyde-alcohol dehydrogenase CPF_2855 214 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110800940 Common - pseudouridine synthase, RluA family CPF_1414 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110800226 Common - hypothetical protein CPF_1304 34 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110800647 Common spoVAE stage V sporulation protein AE CPF_2302 15 None None None 110798996 Common - protein kinase CPF_1991 164 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 110801170 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase CPF_2115 214 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 110801014 Common - hypothetical protein CPF_1376 14 COG4720 COG4720, Predicted membrane protein Function unknown 110799734 Common - Ser/Thr protein phosphatase family protein CPF_0634 18 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 110801012 Common rfbD dTDP-4-dehydrorhamnose reductase CPF_0481 188 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 110799010 Common - hypothetical protein CPF_1398 12 COG4905 COG4905, Predicted membrane protein Function unknown 110798704 Common - transporter, major facilitator family CPF_1857 223 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110800269 Pathogen - hypothetical protein CPF_2825 1 None None None