Haloquadratum walsbyi DSM 16790, complete genome NC_008212 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 110667066 Common nadE NAD(+) synthase (glutamine-hydrolyzing) HQ1091A 217 COG0171 NadE, NAD synthase Coenzyme metabolism 110667689 Common gpdA glycerol-3-phosphate dehydrogenase chain A HQ1734A 160 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110668668 Common adk adenylate kinase HQ2767A 230 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 110667643 Common trkH Trk-type potassium transport system, permease protein TrkH HQ1686A 122 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110669003 Common citB aconitate hydratase HQ3117A 223 COG1048 AcnA, Aconitase A Energy production and conversion 110667150 Nonpathogen - hypothetical protein HQ1176A 3 None None None 110667364 Nonpathogen - hypothetical protein HQ1402A 3 None None None 110668346 Common tdh oxidoreductase (probable Zn-dependent dehydrogenases, threonine 3-dehydrogenase) HQ2425A 114 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110667675 Common - hypothetical protein HQ1718A 8 None None None 110669274 Common tyrS tyrosyl-tRNA synthetase HQ3400A 142 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667021 Common serB phosphoserine phosphatase HQ1044A 150 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110667341 Nonpathogen - hypothetical protein HQ1379A 19 COG1628 COG1628, Uncharacterized conserved protein Function unknown 110668141 Nonpathogen - hypothetical protein HQ2203A 1 None None None 110668685 Nonpathogen - hypothetical protein HQ2786A 5 None None None 110668335 Nonpathogen - hypothetical protein HQ2413A 2 None None None 110667071 Nonpathogen - hypothetical protein HQ1096A 2 None None None 110669186 Nonpathogen phoU ABC transport system regulatory protein HQ3308A 25 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110667888 Common - probable cyclase HQ1938A 31 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 110669333 Common - phosphatase homolog HQ3463A 12 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110668176 Common gufA predicted divalent heavy-metal cations transporter HQ2238A 62 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 110667882 Common - probable light-and/or oxygen-sensing histidine kinase HQ1932A 84 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 110668312 Common acd acyl-CoA dehydrogenase HQ2389A 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110668975 Common - hypothetical protein HQ3089A 22 COG1901 COG1901, Uncharacterized conserved protein Function unknown 110668440 Common btpA photosystem I biogenesis protein homolog HQ2531A 31 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 110667868 Nonpathogen uspA universal stress protein HQ1916A 2 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667987 Common sppA probable signal peptide peptidase HQ2040A 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110668800 Common rpl1P 50S ribosomal protein L1P HQ2903A 246 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 110668749 Nonpathogen - hypothetical protein HQ2851A 1 None None None 110667705 Nonpathogen - hypothetical protein HQ1751A 2 None None None 110669087 Common aslA arylsulfatase HQ3203A 46 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110669446 Nonpathogen repH plasmid replication protein repH HQ3590A 3 None None None 110668755 Common sucD succinate--CoA ligase, alpha subunit (ADP-forming) HQ2857A 216 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 110668555 Nonpathogen - probable transcriptional regulator HQ2649A 25 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 110668913 Nonpathogen - hypothetical protein HQ3025A 1 None None None 110667890 Common - predicted crotonobetainyl-CoA:carnitine CoA-transferase/alpha-methylacyl-CoA racemase HQ1940A 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110667082 Common hisS histidyl-tRNA synthetase HQ1107A 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667892 Common coxM aerobic-type carbon monoxide dehydrogenase,medium subunit HQ1942A 90 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 110668718 Common secY preprotein translocase subunit SecY HQ2819A 57 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 110668006 Nonpathogen - hypothetical protein HQ2061A 3 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110668093 Nonpathogen - hypothetical protein HQ2152A 2 None None None 110667437 Nonpathogen - hypothetical protein HQ1476A 2 None None None 110669120 Nonpathogen - hypothetical protein HQ3238A 1 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110667531 Common metG methionyl-tRNA synthetase HQ1572A 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667963 Nonpathogen - probable tRNA splicing protein, cyclic phosphodiesterase HQ2015A 4 None None None 110668447 Common - hypothetical protein HQ2538A 23 COG4276 COG4276, Uncharacterized conserved protein Function unknown 110668847 Common - IS1341-type transposase HQ2954A 75 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668083 Common - signal-transducing histidine kinase; response regulator; PAS/PAC domain protein HQ2141A 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110669482 Common ureF urease accessory protein HQ3631A 32 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 110668826 Common - hypothetical protein HQ2933A 26 COG5282 COG5282, Uncharacterized conserved protein Function unknown 110668677 Common gatD glutamyl-tRNA(Gln) amidotransferase subunit D HQ2776A 139 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 110668768 Nonpathogen - hypothetical protein HQ2870A 3 None None None 110669118 Nonpathogen - conserved riboflavin biosynthetic operon protein; probable transtriptional regulator HQ3236A 34 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 110669267 Common rpoA2 DNA-directed RNA polymerase subunit A'' (subunit C) HQ3393A 160 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 110667464 Nonpathogen srp19 signal recognition particle 19K protein HQ1503A 21 COG1400 SEC65, Signal recognition particle 19 kDa protein Intracellular trafficking and secretion 110669324 Nonpathogen - hypothetical protein HQ3453A 1 None None None 110668597 Common gtl glycosyltransferase (probable dolichyl-phosphate beta-D-mannosyltransferase) HQ2694A 141 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110668777 Nonpathogen metE 5-methyltetrahydropteroyltriglutamate--homocyste ine S-methyltransferase, methionine synthase II HQ2880A 12 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 110668449 Common amyA alpha-amylase (Glucan 1,4-alpha-maltohydrolase) HQ2540A 168 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110667823 Nonpathogen - rhomboid family protein/intramembrane serine protease HQ1869A 4 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110669411 Nonpathogen - hypothetical protein HQ3550A 3 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 110667089 Nonpathogen - hypothetical protein HQ1115A 3 None None None 110667948 Common - predicted dehydrogenase HQ1999A 222 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 110668529 Common - hypothetical protein HQ2623A 107 COG2135 COG2135, Uncharacterized conserved protein Function unknown 110667874 Nonpathogen - hypothetical protein HQ1923A 1 None None None 110669496 Nonpathogen trm1 N(2),N(2)-dimethylguanosine tRNA methyltransferase HQ3646A 38 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 110668858 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ2965A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110669566 Common argD acetylornithine aminotransferase HQ3717A 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 110669131 Nonpathogen atpH H(+)-transporting two-sector ATPase, subunit H (A-type ATP synthase) HQ3250A 3 None None None 110669211 Nonpathogen - hypothetical protein HQ3333A 4 None None None 110667781 Nonpathogen - hypothetical protein HQ1826A 1 None None None 110667851 Common - hypothetical protein HQ1899A 10 COG2253 COG2253, Uncharacterized conserved protein Function unknown 110667358 Common ribC riboflavin synthase subunit alpha HQ1396A 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 110668483 Nonpathogen - hypothetical protein HQ2576A 18 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 110669365 Nonpathogen - hypothetical protein HQ3502A 2 None None None 110669392 Nonpathogen - hypothetical protein HQ3530A 3 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110668164 Common pncA isochorismatase HQ2226A 68 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110669179 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ3299A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667125 Common nthA endonuclease III; DNA-(apurinic or apyrimidinic site) lyase HQ1151A 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 110667169 Nonpathogen - probable cell surface glycoprotein HQ1196A 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667417 Common mutL DNA mismatch repair protein MutL HQ1456A 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 110669140 Nonpathogen - hypothetical protein HQ3259A 4 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 110667993 Common trzA probable N-ethylammeline chlorohydrolase (S-triazine hydrolase ) HQ2048A 39 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110667832 Common pyrI aspartate carbamoyltransferase regulatory subunit HQ1878A 65 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 110667400 Nonpathogen cca tRNA CCA-pyrophosphorylase HQ1438A 34 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 110668064 Nonpathogen - hypothetical protein HQ2121A 4 None None None 110667032 Nonpathogen - hypothetical protein HQ1055A 3 None None None 110668186 Nonpathogen - hypothetical protein HQ2250A 1 None None None 110667916 Nonpathogen - hypothetical protein HQ1966A 1 None None None 110668366 Common rbsB ABC-type transport system, substrate-binding protein HQ2450A 99 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110669042 Common mutL DNA mismatch repair protein MutL HQ3157A 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 110669553 Nonpathogen - probable phosphate/sulfate permease HQ3704A 4 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 110667727 Nonpathogen gvpJ gas-vesicle operon protein gvpJ HQ1773A 5 None None None 110669285 Nonpathogen - hypothetical protein HQ3411A 2 None None None 110667478 Nonpathogen - transcription regulator / transcriptional repressor CinR HQ1517A 18 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 110667149 Common - transporter of the drug/metabolite transporter (DMT) superfamily HQ1175A 90 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 110667686 Nonpathogen cdc6_ cell division control protein cdc6 homolog HQ1731A 9 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110669540 Nonpathogen hjc Holliday junction resolvase HQ3690A 20 COG1591 COG1591, Holliday junction resolvase - archaeal type DNA replication, recombination, and repair 110668112 Nonpathogen - hypothetical protein HQ2173A 3 None None None 110667140 Common ths thermosome subunit HQ1166A 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110669586 Common - probable GTP-binding protein HQ3738A 59 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 110669491 Common pepB aminopeptidase, probable leucyl aminopeptidase HQ3641A 64 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110669468 Common urtC ABC-type urea transport system, permease protein II HQ3617A 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110667160 Nonpathogen - hypothetical protein HQ1187A 3 None None None 110668992 Nonpathogen - hypothetical protein HQ3106A 4 None None None 110667559 Nonpathogen - hypothetical protein HQ1600A 1 None None None 110669090 Common - cation transporter (probable substrates zinc/cadmium) HQ3206A 193 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110667116 Nonpathogen - hypothetical protein HQ1142A 1 None None None 110669216 Nonpathogen - IS200-type transposase (nonfunctional,N-terminal part) HQ3340A 3 None None None 110667908 Nonpathogen - hypothetical protein HQ1958A 11 None None None 110667735 Nonpathogen gvpC gas-vesicle protein gvpC HQ1781A 2 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 110668867 Nonpathogen - hypothetical protein HQ2976A 1 None None None 110669513 Nonpathogen - hypothetical protein HQ3663A 9 None None None 110668659 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ2758A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110669006 Common - hypothetical protein HQ3120A 44 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110669168 Nonpathogen - hypothetical protein HQ3287A 1 None None None 110668613 Common - probable acetyltransferase HQ2711A 29 COG0456 RimI, Acetyltransferases General function prediction only 110668729 Nonpathogen rps4R 30S ribosomal protein S4e HQ2830A 34 COG1471 RPS4A, Ribosomal protein S4E Translation, ribosomal structure and biogenesis 110668399 Common cinA CinA-like domain protein HQ2488A 158 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 110667274 Common dppD ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein I HQ1307A 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110667441 Common dppB ABC-type dipeptide/oligopeptide/nickel transport system, permease protein I HQ1480A 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110667514 Common - probable hydrolase HQ1555A 73 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110668585 Common - hypothetical protein HQ2679A 41 COG2035 COG2035, Predicted membrane protein Function unknown 110667754 Nonpathogen - hypothetical protein HQ1800A 2 None None None 110667420 Nonpathogen - hypothetical protein HQ1459A 2 None None None 110667546 Nonpathogen - hypothetical protein HQ1587A 1 None None None 110667578 Common livJ ABC-type branched-chain amino acid transport systems, substrate-binding protein HQ1619A 50 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110668535 Common aspC PLP-dependent aminotransferase (probable aspartate aminotransferase ) HQ2629A 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110667195 Common - sodium/arsenite symporter family protein HQ1225A 150 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 110668450 Nonpathogen - probable transposase (fragment) HQ2541A 1 None None None 110668190 Common - hypothetical protein HQ2254A 11 None None None 110667788 Common cbiL cobalt-precorrin-2 C(20)-methyltransferase HQ1833A 115 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 110668072 Nonpathogen - hypothetical protein HQ2129A 2 None None None 110668792 Nonpathogen rpoF DNA-directed RNA polymerase subunit F HQ2895A 20 COG1460 COG1460, Uncharacterized protein conserved in archaea Function unknown 110668077 Nonpathogen - hypothetical protein HQ2134A 1 None None None 110667012 Common arsA transport ATPase (probable substrate arsenite) HQ1035A 89 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 110668457 Nonpathogen - probable endonuclease associated protein HQ2548A 34 COG1833 COG1833, Uncharacterized conserved protein Function unknown 110669570 Common cyc unspecific monooxygenase (cytochrome P450) HQ3721A 75 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 110668199 Nonpathogen - hypothetical protein HQ2263A 1 COG3428 COG3428, Predicted membrane protein Function unknown 110668649 Nonpathogen - hypothetical protein HQ2748A 2 None None None 110667302 Nonpathogen rpoE2 DNA-directed RNA polymerase subunit E'' HQ1338A 27 COG2093 COG2093, DNA-directed RNA polymerase, subunit E'' Transcription 110668634 Common glnH ABC-type glutamine/glutamate/polar amino acids transport system, substrate-binding protein HQ2732A 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110668740 Nonpathogen rpl4lp 50S ribosomal protein L4P HQ2841A 34 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 110668698 Common caaX CAAX prenyl proteinase / zinc metalloproteinase HQ2799A 82 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 110668788 Nonpathogen - small nuclear ribonucleoprotein (snRNP) homolog HQ2891A 23 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 110669108 Common - hypothetical protein HQ3226A 12 None None None 110668903 Nonpathogen - hypothetical protein HQ3015A 6 COG2457 COG2457, Uncharacterized conserved protein Function unknown 110669170 Common trsE transfer complex protein homolog HQ3289A 21 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 110668876 Common - transcriptional regulator (probable sugar-specific) HQ2987A 25 COG1378 COG1378, Predicted transcriptional regulators Transcription 110669080 Common - hypothetical protein HQ3196A 8 None None None 110668225 Nonpathogen - hypothetical protein HQ2294A 6 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 110668734 Nonpathogen rpl29 50S ribosomal protein L29 HQ2835A 14 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 110667814 Nonpathogen - hypothetical protein HQ1860A 2 None None None 110668388 Common dppC ABC-type dipeptide/oligopeptide/nickel transport systems, permease protein HQ2475A 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110667045 Common hsp20 hsp20-type chaperone HQ1069A 76 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110667621 Common pyrE orotate phosphoribosyltransferase HQ1664A 23 COG0856 COG0856, Orotate phosphoribosyltransferase homologs Nucleotide transport and metabolism 110667897 Nonpathogen - hypothetical protein HQ1947A 5 None None None 110669068 Common livM ABC-type branched-chain amino acid transport system, permease protein II HQ3184A 149 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110669056 Common fer1 dnaJ N-terminal domain / ferredoxin fusion protein HQ3171A 57 COG0633 Fdx, Ferredoxin Energy production and conversion 110667386 Nonpathogen rpl15R 50S ribosomal protein L15e HQ1424A 34 COG1632 RPL15A, Ribosomal protein L15E Translation, ribosomal structure and biogenesis 110668723 Nonpathogen rpl19e 50S ribosomal protein L19e HQ2824A 34 COG2147 RPL19A, Ribosomal protein L19E Translation, ribosomal structure and biogenesis 110669404 Common - arylsulfatase HQ3543A 44 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110667319 Common - IS1341-type transposase HQ1356A 36 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668250 Common msrA peptide methionine sulfoxide reductase (S-form specific) HQ2324A 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110669237 Common pgsA probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Phosphatidylglycerophosphate synthase) (PGP synthase) HQ3362A 61 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110667307 Common ham1 Nucleoside-triphosphatase HQ1343A 228 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 110667610 Common trxB thioredoxin reductase (NADPH) HQ1652A 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110668840 Common guaA guanosine monophosphate synthetase (glutamine-hydrolyzing) (GMP synthase) HQ2947A 232 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 110669530 Nonpathogen cdc6 cell division control protein 6 HQ3680A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110667617 Common purA adenylosuccinate synthase HQ1660A 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 110667257 Nonpathogen - hypothetical protein HQ1290A 3 None None None 110669478 Common ureA urease subunit gamma HQ3627A 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 110669431 Common - IS1341-type transposase HQ3574A 57 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667200 Common ipp inorganic pyrophosphatase HQ1231A 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 110667711 Nonpathogen - hypothetical protein HQ1757A 2 None None None 110669221 Common hsp20 hsp20 type chaperone HQ3346A 24 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110667791 Nonpathogen cbiN CbiN protein (probable ABC-type cobalt transport system, periplasmic component) HQ1836A 2 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 110667333 Nonpathogen - hypothetical protein HQ1371A 8 None None None 110667053 Nonpathogen - hypothetical protein HQ1077A 4 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 110667955 Common - probable S-adenosylmethionine-dependent methyltransferase HQ2006A 71 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110669316 Common amtB ammonium transporter HQ3444A 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 110668228 Common cbiC precorrin-8X methylmutase HQ2297A 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 110668663 Nonpathogen aroK shikimate kinase HQ2762A 27 COG1685 COG1685, Archaeal shikimate kinase Amino acid transport and metabolism / Coenzyme metabolism 110668897 Nonpathogen - hypothetical protein HQ3009A 2 None None None 110667329 Common cxp predicted carboxypeptidase HQ1367A 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 110668525 Common lrp transcription regulator HQ2619A 94 COG1522 Lrp, Transcriptional regulators Transcription 110668475 Common gcs2 carboxylate-amine ligase HQ2566A 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 110668647 Nonpathogen phoU probable transport system regulatory protein HQ2746A 26 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110669172 Common - bacterial conjugation protein homolog HQ3291A 16 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 110667338 Common - hypothetical protein HQ1376A 15 COG0546 Gph, Predicted phosphatases General function prediction only 110669438 Nonpathogen - hypothetical protein HQ3581A 1 None None None 110669536 Nonpathogen pcn DNA polymerase sliding clamp HQ3686A 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 110669226 Nonpathogen - conserved tyrA operon protein HQ3351A 10 None None None 110667476 Nonpathogen rnp2 ribonuclease P protein component 2 HQ1515A 6 COG1369 POP5, RNase P/RNase MRP subunit POP5 Translation, ribosomal structure and biogenesis 110667101 Common oxlT major facilitator superfamily oxalate/formate antiporter HQ1127A 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110669454 Nonpathogen - hypothetical protein HQ3598A 3 None None None 110668760 Common ubiA prenyltransferase HQ2862A 13 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 110668349 Nonpathogen - hypothetical protein HQ2429A 4 COG3369 COG3369, Uncharacterized conserved protein Function unknown 110669471 Common nikR transcription regulator; probably nickel responsive regulator HQ3620A 64 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 110667449 Common ggt gamma-glutamyltransferase HQ1488A 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 110667322 Common pepB aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) HQ1359A 37 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110669296 Nonpathogen tif6 translation initiation factor IF-6 HQ3422A 33 COG1976 TIF6, Translation initiation factor 6 (eIF-6) Translation, ribosomal structure and biogenesis 110667502 Nonpathogen - conserved hypothetical protein (probable surface protein) HQ1543A 13 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 110668091 Nonpathogen - putative protein-tyrosine-phosphatase HQ2150A 3 None None None 110668970 Common nudF ADP-ribose pyrophosphatase; Mut/nudix family protein HQ3084A 141 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110668877 Common graD glucose-1-phosphate thymidylyltransferase HQ2989A 239 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 110667581 Common dsbG protein-disulfide isomerase HQ1622A 12 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 110667798 Common msrA methionine sulfoxide reductase A HQ1843A 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110667167 Nonpathogen - hypothetical protein HQ1194A 3 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667237 Common csp probable cold shock protein HQ1268A 9 COG1278 CspC, Cold shock proteins Transcription 110668505 Common phnD ABC-type phosphate/phosphonate transport system,substrate-binding protein HQ2598A 18 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 110668024 Common - DNA repair helicase HQ2079A 92 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 110669197 Common hcaD ferredoxin:NAD+ oxidoreductase HQ3319A 200 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110669250 Nonpathogen - hypothetical protein HQ3376A 4 None None None 110668034 Nonpathogen - hypothetical protein HQ2089A 1 None None None 110668138 Nonpathogen - hypothetical protein HQ2199A 1 None None None 110668354 Nonpathogen - hypothetical protein HQ2435A 2 None None None 110668485 Common malQ 4-alpha-glucanotransferase HQ2578A 118 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 110668084 Nonpathogen - hypothetical protein HQ2142A 2 None None None 110667205 Common arsA transport ATPase (probable substrate arsenite) HQ1236A 50 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 110668540 Common rad25 DNA repair protein Rad25 HQ2634A 130 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 110667944 Nonpathogen - hypothetical protein HQ1995A 1 None None None 110669531 Common mutS3 DNA mismatch repair protein MutS homolog, MutS3 HQ3681A 82 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110668069 Nonpathogen - hypothetical protein HQ2126A 1 None None None 110668890 Common prkA predicted serine protein kinase HQ3002A 33 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 110668400 Nonpathogen - hypothetical protein HQ2489A 4 None None None 110669526 Common surE acid phosphatase HQ3676A 182 COG0496 SurE, Predicted acid phosphatase General function prediction only 110667744 Nonpathogen - hypothetical protein HQ1790A 1 None None None 110668496 Nonpathogen - hypothetical protein HQ2589A 2 None None None 110669551 Common recJ single-stranded-DNA-specific exonuclease HQ3702A 31 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110668512 Common phnM Phosphonate metabolism protein PhnM HQ2605A 69 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 110668422 Nonpathogen - hypothetical protein HQ2513A 1 None None None 110667294 Nonpathogen tadC type II secretion system, transmembrane protein TadC HQ1329A 6 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 110667960 Nonpathogen - hypothetical protein HQ2012A 1 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 110667928 Common pncB nicotinate phosphoribosyltransferase HQ1979A 66 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 110668324 Common menE O-succinylbenzoic acid--CoA ligase HQ2402A 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110669092 Common map methionine aminopeptidase HQ3208A 219 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 110669310 Nonpathogen - hypothetical protein HQ3438A 4 None None None 110668999 Common - predicted electron-transferring-flavoprotein dehydrogenase / geranylgeranyl hydrogenase homolog HQ3113A 76 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 110668994 Common glcK glucokinase HQ3108A 159 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110668157 Nonpathogen - hypothetical protein HQ2219A 4 None None None 110669569 Common rad3b DNA repair helicase homolog HQ3720A 62 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 110667481 Nonpathogen - predicted electron-transferring-flavoprotein dehydrogenase HQ1520A 31 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 110667903 Nonpathogen - hypothetical protein HQ1953A 3 None None None 110669355 Nonpathogen - hypothetical protein HQ3487A 1 None None None 110667639 Common - putative monovalent cation/H+ antiporter subunit D HQ1682A 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 110669508 Nonpathogen - hypothetical protein HQ3658A 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110668865 Common - predicted metal-dependent hydrolase of the TIM-barrel fold HQ2974A 31 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 110669142 Common manC mannose-1-phosphate guanylyltransferase HQ3261A 162 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 110666983 Nonpathogen - hypothetical protein HQ1007A 10 COG1617 COG1617, Uncharacterized conserved protein Function unknown 110669362 Nonpathogen - hypothetical protein HQ3499A 4 COG1378 COG1378, Predicted transcriptional regulators Transcription 110667604 Common nuoL NADH dehydrogenase, subunit L (ubiquinone) HQ1646A 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 110667632 Common phaF pH adaptation potassium efflux system protein F; sodium-potassium/hydrogen antiporter subunit F HQ1675A 13 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 110669011 Common cofG FO synthase subunit 1 HQ3125A 51 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 110668778 Common metE methionine synthase HQ2881A 151 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 110667096 Nonpathogen - hypothetical protein HQ1122A 3 None None None 110667143 Nonpathogen - probable transcription regulator, ArsR like HQ1169A 14 None None None 110667243 Common - putative thiazole biosynthetic enzyme HQ1276A 31 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 110667989 Nonpathogen - hypothetical protein HQ2044A 1 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110667373 Common cbiB cobalamine biosynthesis protein (adenosylcobinamide biosynthesis protein) HQ1411A 147 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 110668657 Common livM ABC-type branched-chain amino acid transport systems, permease protein II HQ2756A 139 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110667225 Nonpathogen - H/ACA RNA-protein complex component Nop10p HQ1256A 9 COG2260 COG2260, Predicted Zn-ribbon RNA-binding protein Translation, ribosomal structure and biogenesis 110667771 Nonpathogen - ISH9-type transposase (TCE34) (nonfunctional,N-terminal part) HQ1816B 4 None None None 110667778 Nonpathogen - hypothetical protein HQ1823A 1 None None None 110668242 Nonpathogen - phbC-phbA intergenic region protein HQ2311A 2 None None None 110668601 Nonpathogen - hypothetical protein HQ2698A 4 None None None 110668945 Common - hypothetical protein HQ3058A 34 COG1395 COG1395, Predicted transcriptional regulator Transcription 110667663 Common sufC ABC-type transport system involved in Fe-S cluster assembly, ATP-binding protein HQ1706A 214 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 110667657 Common mre11 DNA double-strand break repair protein mre11 HQ1700A 55 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 110668407 Nonpathogen - glycine-rich protein HQ2497A 1 COG4907 COG4907, Predicted membrane protein Function unknown 110668679 Nonpathogen - transcription regulator HQ2779A 17 COG1777 COG1777, Predicted transcriptional regulators Transcription 110667124 Nonpathogen - hypothetical protein HQ1150A 1 None None None 110669248 Common cumB cytosine/adenosine deaminases HQ3374A 184 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 110669203 Nonpathogen - hypothetical protein HQ3325A 5 None None None 110667554 Common lepW probable signal peptidase I (SPase I) (Leader peptidase I) HQ1595A 10 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110668707 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ2808A 164 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110668369 Common rbsC2 ABC-type ribose transport system, permease protein HQ2453A 134 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 110667246 Nonpathogen - peptidyl-tRNA hydrolase HQ1279A 34 COG1990 COG1990, Uncharacterized conserved protein Function unknown 110668103 Nonpathogen - hypothetical protein HQ2163A 8 COG4190 COG4190, Predicted transcriptional regulator Transcription 110668683 Nonpathogen - hypothetical protein HQ2783A 4 None None None 110668465 Common cysK cysteine synthase HQ2556A 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 110668319 Nonpathogen - hypothetical protein HQ2397A 1 None None None 110668578 Common dhaK1 dihydroxyacetone kinase HQ2672A 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 110667210 Nonpathogen nusG transcription antitermination protein NusG HQ1241A 34 COG0250 NusG, Transcription antiterminator Transcription 110667696 Common - probable FAD-dependent monooxygenase HQ1741A 5 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110669133 Nonpathogen - hypothetical protein HQ3252A 2 None None None 110667525 Common - probable short chain dehydrogenase/ reductase HQ1566A 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110669343 Nonpathogen - hypothetical protein HQ3475A 2 None None None 110667137 Common lon endopeptidase La HQ1163A 205 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 110668717 Nonpathogen - hypothetical protein HQ2818A 1 None None None 110668098 Nonpathogen - hypothetical protein HQ2158A 2 None None None 110668626 Nonpathogen - hypothetical protein HQ2724A 3 None None None 110667028 Common valS valyl-tRNA synthetase HQ1051A 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110668604 Common ilvB acetolactate synthase large subunit HQ2702A 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110668236 Nonpathogen - cobalamin transport operon protein HQ2305A 1 None None None 110668959 Common uvrA excinuclease ABC chain A HQ3072A 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 110667861 Nonpathogen nuc endonuclease Staphylococcal nuclease-like HQ1909A 1 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 110668202 Nonpathogen - probable periplasmic serine proteinase (fragment) HQ2266A 1 None None None 110668530 Common - hypothetical protein HQ2624A 23 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 110668498 Common - hypothetical protein HQ2591A 39 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110668855 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ2962A 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110667835 Common fbp fructose-1,6-bisphosphatase HQ1881A 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 110667232 Nonpathogen - conserved smc operon protein HQ1263A 24 COG1354 COG1354, Uncharacterized conserved protein Function unknown 110667292 Nonpathogen - hypothetical protein HQ1327A 1 None None None 110667284 Common - IS1341-type transposase (nonfunctional,N-terminal part) HQ1317A 6 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668967 Common azlC ABC-type transport system permease protein (probable substrates branched-chain amino acids),azaleucine resistance protein HQ3080A 100 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 110667299 Common tif2g translation initiation factor IF-2 subunit gamma HQ1335A 249 COG5257 GCD11, Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) Translation, ribosomal structure and biogenesis 110667909 Nonpathogen - hypothetical protein HQ1959A 5 None None None 110667252 Nonpathogen - conserved rpo operon protein HQ1285A 1 COG2892 COG2892, Uncharacterized protein conserved in archaea Function unknown 110669260 Common hom homoserine dehydrogenase HQ3386A 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 110669307 Nonpathogen - posible NMD protein affecting ribosome stability and mRNA decay HQ3435A 28 COG1499 NMD3, NMD protein affecting ribosome stability and mRNA decay Translation, ribosomal structure and biogenesis 110667286 Common act acyl-CoA thioester hydrolase HQ1319A 86 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 110668025 Common smc chromosome segregation protein HQ2080A 54 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 110669418 Common - ISRSO17-transposase HQ3557A 28 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 110667001 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)m ethylideneamino] imidazole-4-carboxamide isomerase HQ1025A 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 110667007 Nonpathogen - hypothetical protein HQ1030A 2 None None None 110668943 Nonpathogen - hypothetical protein HQ3055A 5 None None None 110668885 Common sdhC succinate dehydrogenase, subunit C (cytochrome b-556) HQ2997A 19 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 110668434 Nonpathogen - hypothetical protein HQ2525A 1 None None None 110669153 Common - hypothetical protein HQ3272A 8 COG0433 COG0433, Predicted ATPase General function prediction only 110667219 Common - glycosyl tranferase; dolichyl-phosphate beta-glucosyltransferase HQ1250A 36 None None None 110669488 Nonpathogen - hypothetical protein HQ3637A 2 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 110669424 Nonpathogen - hypothetical protein HQ3565A 4 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 110667569 Nonpathogen - conserved cox cluster protein HQ1610A 4 None None None 110667100 Common trkA K+ transport systems, NAD-binding protein HQ1126A 141 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110669519 Common est 3-oxoadipate enol-lactonase HQ3669A 96 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110668807 Nonpathogen - hypothetical protein HQ2911A 1 None None None 110667822 Nonpathogen - probable RNA methylase HQ1868A 29 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 110668041 Common uraA xanthine/uracil permeases HQ2096A 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110668120 Nonpathogen - hypothetical protein HQ2181A 1 None None None 110667466 Nonpathogen - hypothetical protein HQ1505A 14 COG3389 COG3389, Uncharacterized protein conserved in archaea Function unknown 110669494 Nonpathogen - membrane-associated phosphatase homolog, PAP2 family HQ3644A 2 None None None 110668721 Common rps5p 30S ribosomal protein S5P HQ2822A 244 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 110668264 Nonpathogen - hypothetical protein HQ2338A 5 COG2383 COG2383, Uncharacterized conserved protein Function unknown 110668845 Nonpathogen cdc6_ cell division control protein cdc6 homolog (fragment probably interupted by IS element) HQ2952A 11 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110668574 Common traB probable plasmid transfer protein HQ2668A 34 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 110667965 Nonpathogen - conserved hypothetical protein (probable surface protein) HQ2017A 5 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 110667010 Common cobW cobalamin synthesis protein/P47K HQ1033A 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110667435 Common rbsK Ribokinase HQ1474A 125 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110667769 Common salY ABC-type antimicrobial peptide transport system,permease protein HQ1815A 40 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110669481 Common ureE urease accessory protein UreE HQ3630A 16 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 110669395 Common - ABC-type multidrug/lipid transport system,permease and ATP-binding protein HQ3533A 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110667562 Nonpathogen dph5 diphthine synthase HQ1603A 34 COG1798 DPH5, Diphthamide biosynthesis methyltransferase Translation, ribosomal structure and biogenesis 110669329 Common mdhA malate dehydrogenase HQ3459A 183 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 110669013 Common thiH FO synthase subunit 2 HQ3127A 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 110669322 Common hemX uroporphyrin-III C-methyltransferase HQ3451A 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 110667076 Common - probable membrane associated metalloprotease HQ1101A 41 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 110669370 Common nudF ADP-ribose pyrophosphatase HQ3508A 96 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110667946 Nonpathogen - hypothetical protein HQ1997A 1 None None None 110667853 Nonpathogen - hypothetical protein HQ1901A 4 None None None 110668281 Nonpathogen pssA CDP-diacylglycerol--serine O-phosphatidyltransferase (Phosphatidylserine synthase) HQ2356A 12 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110666977 Nonpathogen cdc6_1 cell division control protein cdc6 homolog HQ1001A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110667392 Common - CBS domain protein HQ1430A 118 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 110668589 Common galE nucleoside-diphosphate-sugar epimerase 1 (probable UDP-glucose 4-epimerase) HQ2683A 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110669027 Nonpathogen - hypothetical protein HQ3142A 4 None None None 110667429 Common pstB ABC-type phosphate transport system, ATP-binding protein HQ1468A 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 110667678 Common glo lactoylglutathione lyase HQ1721A 65 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110669564 Common argC N-acetyl-gamma-glutamyl-phosphate reductase HQ3715A 193 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 110668310 Nonpathogen - hypothetical protein HQ2387A 1 None None None 110669050 Nonpathogen - hypothetical protein HQ3165A 4 None None None 110668655 Common livJ ABC-type branched-chain amino acid transport system, substrate-binding protein HQ2754A 100 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110667217 Common - homolog to Rieske iron sulfur protein HQ1248A 18 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 110667742 Common - hypothetical protein HQ1788A 20 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110668506 Common phnG Phosphonate metabolism protein PhnG HQ2599A 4 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 110667356 Common gapB glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) HQ1394A 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110668037 Nonpathogen - hypothetical protein HQ2092A 2 None None None 110668752 Common - hypothetical protein HQ2854A 11 None None None 110669020 Nonpathogen - predicted cell surface protein/ lipoprotein-putative microfilarial sheath protein HQ3135A 1 None None None 110668838 Nonpathogen stt3 transmembrane oligosaccharyl transferase HQ2945A 8 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 110667884 Common xup xanthine/uracil permease family protein. probable substrate ascorbate HQ1934A 129 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 110668666 Common cmk cytidylate kinase HQ2765A 38 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 110667080 Nonpathogen - hypothetical protein HQ1105A 28 COG2118 COG2118, DNA-binding protein General function prediction only 110668348 Common aslA arylsulfatase HQ2428A 24 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110668288 Nonpathogen - hypothetical protein HQ2364A 2 COG3462 COG3462, Predicted membrane protein Function unknown 110668325 Nonpathogen - probable phosphoesterase HQ2403A 26 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 110667787 Common cbiF precorrin-4 C11-methyltransferase HQ1832A 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 110668477 Nonpathogen nop56 probable pre-rRNA-processing protein nop56 HQ2568A 34 COG1498 SIK1, Protein implicated in ribosomal biogenesis, Nop56p homolog Translation, ribosomal structure and biogenesis 110668851 Nonpathogen - hypothetical protein HQ2958A 9 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 110669001 Common pan1 proteasome-activating nucleotidase HQ3115A 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 110669057 Common cbs CBS domain protein HQ3172A 58 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 110667865 Nonpathogen - hypothetical protein HQ1913A 1 None None None 110668907 Nonpathogen - hypothetical protein HQ3019A 1 None None None 110667152 Common - nudix family protein HQ1178A 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110668174 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase HQ2236A 137 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 110668395 Nonpathogen - IS200-type transposase (nonfunctional,N-terminal part) HQ2483A 3 None None None 110669049 Nonpathogen - hypothetical protein HQ3164A 4 None None None 110667606 Common nuoN NADH dehydrogenase, subunit N (ubiquinone) HQ1648A 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 110667760 Common dsbG protein-disulfide isomerase HQ1806A 59 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 110668611 Common ptsI Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I) HQ2709A 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 110667999 Common - signal-transducing histidine kinase HQ2054A 22 None None None 110667671 Common gltB glutamate synthase large subunit HQ1714A 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 110668337 Nonpathogen - hypothetical protein HQ2415A 5 None None None 110668790 Common purF amidophosphoribosyltransferase HQ2893A 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 110667544 Common fhuD ABC-type Fe3+-hydroxamate transport system,substrate-binding protein HQ1585A 79 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110668558 Common gyrB DNA gyrase / DNA topoisomerase II subunit B HQ2652A 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110668799 Nonpathogen rplP0 acidic ribosomal protein P0 HQ2902A 33 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 110668584 Common - S-adenosylmethionine-dependent methyltransferase homolog HQ2678A 96 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110668621 Nonpathogen priA DNA primase small subunit HQ2719A 31 COG1467 PRI1, Eukaryotic-type DNA primase, catalytic (small) subunit DNA replication, recombination, and repair 110669072 Nonpathogen - hypothetical protein HQ3188A 2 None None None 110668377 Common sod superoxide dismutase HQ2461A 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 110669376 Nonpathogen - hypothetical protein HQ3514A 1 None None None 110668557 Common gyrA DNA gyrase / DNA topoisomerase II subunit A HQ2651A 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110669079 Common pyrG CTP synthetase HQ3195A 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 110668784 Common - hypothetical protein HQ2887A 76 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 110669385 Nonpathogen - protein transglucosylase HQ3524A 6 None None None 110669448 Nonpathogen - hypothetical protein HQ3592A 3 None None None 110668990 Common - AAA-type ATPase HQ3104A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110668470 Common - acetyltransferase homolog HQ2561A 162 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110668889 Common - hypothetical protein HQ3001A 69 COG2718 COG2718, Uncharacterized conserved protein Function unknown 110668008 Nonpathogen - hypothetical protein HQ2063A 1 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110668547 Common dnaJ chaperone protein DnaJ HQ2641A 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110668701 Nonpathogen - hypothetical protein HQ2802A 1 None None None 110668915 Nonpathogen - hypothetical protein HQ3027A 4 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110668455 Nonpathogen - hypothetical protein HQ2546A 4 None None None 110667894 Common coxL aerobic-type carbon monoxide dehydrogenase,large subunit HQ1944A 104 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110668383 Common - probable tRNA/rRNA methyltransferase HQ2467A 158 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 110668537 Common ssuC ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Sulfonate ABC transporter permease protein HQ2631A 164 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110668379 Common phr deoxyribodipyrimidine photolyase HQ2463A 132 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 110667512 Nonpathogen - hypothetical protein HQ1553A 3 None None None 110668861 Nonpathogen - hypothetical protein HQ2968A 4 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 110668036 Nonpathogen - hypothetical protein HQ2091A 1 None None None 110669443 Nonpathogen - hypothetical protein HQ3587A 7 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110667193 Nonpathogen - hypothetical protein HQ1223A 3 None None None 110667409 Common - hypothetical protein HQ1448A 138 COG0432 COG0432, Uncharacterized conserved protein Function unknown 110667272 Nonpathogen - hypothetical protein HQ1305A 4 None None None 110668747 Common capA poly-gamma-glutamate biosynthesis/capsule biosynthesis protein HQ2849A 80 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 110667812 Nonpathogen - IS200-type transposase (nonfunctional,N-terminal part) HQ1858A 3 None None None 110668136 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ2197A 164 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110667500 Nonpathogen - probable transcription regulator, ArsR family HQ1541A 14 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 110667159 Nonpathogen - hypothetical protein HQ1186A 2 None None None 110667596 Common nuoA NADH dehydrogenase, subunit A (ubiquinone) HQ1637A 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 110668884 Nonpathogen sdhD succinate dehydrogenase, subunit D (membrane anchor protein) HQ2996A 4 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 110667234 Nonpathogen - conserved smc operon protein HQ1265A 3 None None None 110668070 Common chrA chromate transport protein HQ2127A 115 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 110669309 Nonpathogen - hypothetical protein HQ3437A 2 None None None 110668218 Common - major facilitator superfamily transporter HQ2285A 46 None None None 110668148 Common narK nitrate/nitrite transporter HQ2210A 90 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110669164 Nonpathogen - hypothetical protein HQ3283A 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667452 Nonpathogen - hypothetical protein HQ1491A 10 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 110667808 Nonpathogen - hypothetical protein HQ1853A 3 None None None 110668194 Nonpathogen - hypothetical protein HQ2258A 3 None None None 110668223 Common oxlT oxalate/formate antiporter HQ2291A 46 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110669166 Nonpathogen - hypothetical protein HQ3285A 1 None None None 110667834 Common gdhA glutamate dehydrogenase (NADP+) HQ1880A 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 110667795 Common - probable short chain dehydrogenase/ reductase HQ1840A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110669127 Common atpC V-type ATP synthase subunit C HQ3246A 31 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 110669272 Common - predicted RIO-like serine/threonine protein kinase II HQ3398A 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 110669106 Nonpathogen - hypothetical protein HQ3224A 2 None None None 110669402 Nonpathogen - hypothetical protein HQ3541A 1 None None None 110668786 Common idsA probable trifunctional short-chain (E)-prenyl diphosphate synthase (probable dimethylallyltransferase / probable geranyltranstransferase / probable farnesytranstransferase) HQ2889A 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 110668192 Nonpathogen - hypothetical protein HQ2256A 2 None None None 110667179 Common csg cell surface glycoprotein precursor HQ1207A 38 COG3889 COG3889, Predicted solute binding protein General function prediction only 110668632 Common glnQ ABC-type glutamine/glutamate/polar amino acids transport system, ATP-binding protein HQ2730A 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110668696 Nonpathogen - hypothetical protein HQ2797A 11 COG0011 COG0011, Uncharacterized conserved protein Function unknown 110669441 Nonpathogen - hypothetical protein HQ3584A 10 None None None 110667509 Common petB menaquinol--cytochrome-c reductase (cytochrome bc complex) cytochrome b subunit HQ1550A 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 110667752 Common hat histone acetyltransferase homolog HQ1798A 86 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 110669181 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ3301A 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110668561 Common thiE thiamine-phosphate pyrophosphorylase HQ2655A 205 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110667047 Nonpathogen - hypothetical protein HQ1071A 2 None None None 110667690 Common gpdB anaerobic glycerol-3-phosphate dehydrogenase subunit B HQ1735A 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 110667019 Common thrC threonine synthase HQ1042A 205 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 110667935 Common qor NADPH:quinone reductase HQ1987A 184 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110668771 Common alaS alanine--tRNA ligase HQ2873A 248 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667172 Common sub subtilisin-like serine protease HQ1200A 9 COG3889 COG3889, Predicted solute binding protein General function prediction only 110668305 Common guaB IMP dehydrogenase/ CBS domain protein HQ2382A 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 110668639 Nonpathogen rhaT DMT superfamily drug/metabolite transporter HQ2738A 8 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110667317 Nonpathogen - hypothetical protein HQ1354A 1 None None None 110669380 Common neuA acylneuraminate cytidylyltransferase HQ3518A 83 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 110667994 Common guaD N-ethylammeline chlorohydrolase HQ2049A 172 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110669331 Nonpathogen polA2 DNA polymerase II large subunit HQ3461A 26 COG1933 COG1933, Archaeal DNA polymerase II, large subunit DNA replication, recombination, and repair 110668240 Common phaB 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase) PhaB HQ2309A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110668368 Common rbsC1 ABC-type ribose transport system, permease protein HQ2452A 107 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 110667930 Common rad3 DNA repair helicase Rad3 HQ1981A 35 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 110668650 Nonpathogen - signal-transducing histidine kinase; PAS/PAC domain protein HQ2749A 4 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110669188 Nonpathogen - hypothetical protein HQ3310A 13 COG3612 COG3612, Uncharacterized protein conserved in archaea Function unknown 110667697 Nonpathogen - probable transcription regulator HQ1742A 4 COG3355 COG3355, Predicted transcriptional regulator Transcription 110668003 Nonpathogen - hypothetical protein HQ2058A 1 None None None 110668356 Common - major facilitator superfamily transporter HQ2439A 137 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110668188 Common cadA cadmium-transporting ATPase HQ2252A 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110669044 Common moxR MoxR-like ATPase HQ3159A 171 COG0714 COG0714, MoxR-like ATPases General function prediction only 110669036 Common - hypothetical protein HQ3151A 34 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 110668938 Nonpathogen - hypothetical protein HQ3050A 4 None None None 110669466 Common urtE ABC-type urea transport systems, ATP-binding protein II HQ3615A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110669567 Common argE acetyl-lysine deacetylase HQ3718A 115 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110669416 Common - probable transposase (ISH8/ISH26) HQ3555A 8 None None None 110668442 Common lysE LysE family transporter HQ2533A 78 COG1279 COG1279, Lysine efflux permease General function prediction only 110667114 Common - hypothetical protein HQ1140A 57 COG1430 COG1430, Uncharacterized conserved protein Function unknown 110669420 Nonpathogen - probable sulfatase (fragment) HQ3559A 1 None None None 110668116 Common - hypothetical protein HQ2177A 24 COG3372 COG3372, Uncharacterized conserved protein Function unknown 110666985 Nonpathogen - hypothetical protein HQ1009A 1 None None None 110669559 Common - homolog to dolichol kinase HQ3710A 10 COG0170 SEC59, Dolichol kinase Lipid metabolism 110668766 Common mvaB hydroxymethylglutaryl-CoA synthase HQ2868A 57 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 110669390 Nonpathogen - probable transposase (ISH8/ISH26) HQ3528A 6 None None None 110667688 Common glpK glycerol kinase HQ1733A 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 110668211 Nonpathogen - hypothetical protein HQ2278A 1 None None None 110668711 Nonpathogen - hypothetical protein HQ2812A 1 None None None 110668917 Common pspA probable stress response protein HQ3029A 84 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 110667571 Nonpathogen - conserved cox cluster protein HQ1612A 1 None None None 110669576 Nonpathogen - hypothetical protein HQ3727A 3 None None None 110667733 Nonpathogen gvpO gas-vesicle operon protein gvpO HQ1779A 5 None None None 110668681 Common gpmA phosphoglyceromutase HQ2781A 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 110668086 Nonpathogen - hypothetical protein HQ2145A 1 None None None 110668892 Nonpathogen - hypothetical protein HQ3004A 21 COG1860 COG1860, Uncharacterized protein conserved in archaea Function unknown 110668823 Common dna2 DNA2-like DNA replication helicase HQ2930A 67 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 110669524 Nonpathogen - hypothetical protein HQ3674A 1 None None None 110668957 Common - predicted ATPase HQ3070A 26 COG0433 COG0433, Predicted ATPase General function prediction only 110668624 Nonpathogen - hypothetical protein HQ2722A 3 None None None 110668811 Nonpathogen - cell surface glycoprotein HQ2915A 1 None None None 110668467 Nonpathogen - hypothetical protein HQ2558A 1 None None None 110668580 Common dhaM probable phosphoenolpyruvate-protein phosphoryltransferase HQ2674A 36 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 110668510 Common phnK Phosphonates transport ATP-binding protein PhnK HQ2603A 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 110668996 Nonpathogen - hypothetical protein HQ3110A 4 None None None 110668487 Common nadE NAD(+) synthase (glutamine-hydrolyzing) HQ2580A 231 COG0171 NadE, NAD synthase Coenzyme metabolism 110669528 Nonpathogen - hypothetical protein HQ3678A 4 None None None 110669230 Common porB pyruvate--ferredoxin oxidoreductase, beta subunit HQ3355A 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 110667296 Nonpathogen - hypothetical protein HQ1331A 3 None None None 110668980 Common aceA isocitrate lyase HQ3094A 134 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 110669021 Nonpathogen - IS1341-type transposase (nonfunctional,N-terminal part) HQ3136E 1 None None None 110667637 Common phaD putative monovalent cation/H+ antiporter subunit D HQ1680A 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 110668259 Nonpathogen - hypothetical protein HQ2333A 1 None None None 110667591 Common aspC aspartate aminotransferase HQ1632A 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110668359 Nonpathogen - hypothetical protein HQ2442A 5 None None None 110667979 Nonpathogen xseAs exonuclease VII small subunit HQ2032A 2 None None None 110668594 Common aslA arylsulfatase HQ2690A 40 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110669062 Nonpathogen - probable PUA domain RNA-binding protein HQ3178A 34 COG2016 COG2016, Predicted RNA-binding protein (contains PUA domain) Translation, ribosomal structure and biogenesis 110667922 Common sfsA DNA-binding protein, stimulates sugar fermentation HQ1973A 108 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 110668291 Common - homolog to lyase/ dioxygenase HQ2368A 10 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110669144 Nonpathogen - replication factor A HQ3263A 15 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 110669300 Nonpathogen - hypothetical protein HQ3426A 14 COG2412 COG2412, Uncharacterized conserved protein Function unknown 110668122 Nonpathogen - hypothetical protein HQ2183A 4 None None None 110667829 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase HQ1875A 87 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 110668645 Common - indole-3-acetyl-L-aspartic acid hydrolase HQ2744A 176 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110667312 Common ilvA threonine ammonia-lyase HQ1348A 209 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110667630 Nonpathogen - hypothetical protein HQ1673A 9 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 110669501 Common hit probable histidine triad (HIT) hydrolase HQ3651A 238 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 110668951 Nonpathogen hop halorhodopsin HQ3064A 7 COG5524 COG5524, Bacteriorhodopsin General function prediction only 110667583 Nonpathogen - predicted methyltransferase HQ1624A 36 COG2520 COG2520, Predicted methyltransferase General function prediction only 110667394 Common potB ABC-type spermidine/putrescine transport system,permease domain I HQ1432A 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110668298 Nonpathogen ccdA cytochrome C biogenesis protein/thiol-disulfide transporter HQ2375A 4 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 110667981 Common - hypothetical protein HQ2034A 39 COG3367 COG3367, Uncharacterized conserved protein Function unknown 110667327 Common uvrD DNA helicase II HQ1364A 218 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110668519 Common arsR transcriptional regulator, ArsR family HQ2612A 167 COG0640 ArsR, Predicted transcriptional regulators Transcription 110668725 Common rpl6p 50S ribosomal protein L6P HQ2826A 43 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 110669228 Common pepQ Xaa-Pro aminopeptidase HQ3353A 228 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110669239 Common hisC histidinol-phosphate aminotransferase HQ3364A 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110667612 Common cysS cysteine--tRNA ligase HQ1654A 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110669378 Nonpathogen - ISH3-type transposase (fragment) HQ3516A 3 None None None 110667060 Nonpathogen bat bacterioopsin activator HQ1084A 5 COG3413 COG3413, Predicted DNA binding protein General function prediction only 110668977 Common sppA Protease IV; endopeptidase IV; probable signal peptide peptidase HQ3091A 57 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110667069 Common - hypothetical protein HQ1094A 33 COG3253 COG3253, Uncharacterized conserved protein Function unknown 110667820 Common csp probable cold shock protein HQ1866A 169 COG1278 CspC, Cold shock proteins Transcription 110668094 Common - predicted ATP-dependent Lon-type protease HQ2153A 173 COG4930 COG4930, Predicted ATP-dependent Lon-type protease Posttranslational modification, protein turnover, chaperones 110667474 Nonpathogen rnp3 ribonuclease P protein component 3 HQ1513A 15 COG1603 RPP1, RNase P/RNase MRP subunit p30 Translation, ribosomal structure and biogenesis 110667719 Common opuD probable glycine betaine transport protein HQ1765A 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 110668402 Nonpathogen tfeA transcription initiation factor IIE alpha subunit homolog HQ2491A 29 COG1675 TFA1, Transcription initiation factor IIE, alpha subunit Transcription 110667131 Common trpA tryptophan synthase subunit alpha HQ1157A 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 110669318 Nonpathogen - hypothetical protein HQ3446A 1 None None None 110667164 Nonpathogen - hypothetical protein HQ1191A 1 None None None 110667492 Common oxr oxidoreductase aldo/keto reductase family HQ1533A 188 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 110669116 Common ilvE branched-chain-amino-acid transaminase HQ3234A 219 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110667914 Common bcp peroxiredoxin homolog HQ1964A 223 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110667309 Common trkA potassium transport system, NAD-binding protein HQ1345A 119 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110668709 Nonpathogen - hypothetical protein HQ2810A 1 None None None 110669098 Nonpathogen - hypothetical protein HQ3214A 4 None None None 110667713 Common - hypothetical protein HQ1759A 88 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110668870 Nonpathogen - hypothetical protein HQ2980A 1 None None None 110667122 Nonpathogen - hypothetical protein HQ1148A 1 None None None 110668570 Common - CBS domain protein, probable transcriptional regulator HQ2664A 75 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 110669436 Nonpathogen - hypothetical protein HQ3579D 3 None None None 110667331 Common - predicted ATPase HQ1369A 63 COG1855 COG1855, ATPase (PilT family) General function prediction only 110668181 Common cysA ABC-type sulfate/molybdate transport systems,ATP-binding protein HQ2244A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110669253 Nonpathogen - IS200-type transposase (nonfunctional,C-terminal part) HQ3379B 1 None None None 110667847 Nonpathogen - hypothetical protein HQ1894A 1 None None None 110669155 Common - predicted helicase HQ3274A 126 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 110668414 Nonpathogen - hypothetical protein HQ2504A 17 COG3294 COG3294, Uncharacterized conserved protein Function unknown 110668694 Common suhB inositol-1(or 4)-monophosphatase/ fructose-1,6-bisphosphatase, archaeal type HQ2795A 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 110667304 Nonpathogen rps24e 30S ribosomal protein S24e HQ1340A 27 COG2004 RPS24A, Ribosomal protein S24E Translation, ribosomal structure and biogenesis 110667619 Common purB adenylosuccinate lyase HQ1662A 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 110667488 Nonpathogen - hypothetical protein HQ1528A 1 None None None 110667443 Common dppF ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein II HQ1482A 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110668156 Common gufA predicted divalent heavy-metal cations transporter HQ2218A 8 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 110667725 Nonpathogen gvpL gas-vesicle operon protein gvpL HQ1771A 6 None None None 110669241 Nonpathogen - hypothetical protein HQ3366A 3 None None None 110668805 Common serA phosphoglycerate dehydrogenase HQ2909A 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110669486 Nonpathogen trkA TrkA-potassium uptake domain protein (NAD-binding protein) HQ3635A 11 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110668941 Common crcB protein crcB homolog HQ3053A 33 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 110668532 Nonpathogen - hypothetical protein HQ2626A 4 None None None 110667008 Nonpathogen - hypothetical protein HQ1031A 2 None None None 110667921 Common aldH aldehyde dehydrogenase HQ1972A 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110668238 Common acaB acetyl-CoA C-acyltransferase HQ2307A 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110669291 Nonpathogen - divalent cation transporter, subunit I, MgtE family protein HQ3417A 4 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 110667203 Common nfi endonuclease V (deoxyinosine 3'endonuclease) HQ1234A 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 110668965 Nonpathogen - hypothetical protein HQ3078A 4 None None None 110667454 Common abcA ABC-type transport system ATP-binding protein HQ1493A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110669571 Nonpathogen - hypothetical protein HQ3722A 3 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 110668161 Common - hypothetical protein HQ2223A 73 COG2013 COG2013, Uncharacterized conserved protein Function unknown 110667668 Common - hypothetical protein HQ1711A 16 COG4347 COG4347, Predicted membrane protein Function unknown 110667957 Nonpathogen - hypothetical protein HQ2008A 1 None None None 110667796 Common - major facilitator superfamily transporter HQ1841A 110 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110667837 Common - hypothetical protein HQ1883A 123 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 110667282 Nonpathogen asnC transcriptional regulator containig TrkA-domain protein (NAD-binding protein) HQ1315A 6 COG1522 Lrp, Transcriptional regulators Transcription 110669138 Nonpathogen - hypothetical protein HQ3257A 27 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 110668226 Common chlID magnesium chelatase (protoporphyrin IX magnesium-chelatase) HQ2295A 74 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 110668314 Common apa probable bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (Diadenosine tetraphosphatase) HQ2391A 35 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110667254 Nonpathogen - hypothetical protein HQ1287A 4 None None None 110668802 Common birA biotin--[acetyl-CoA-carboxylase] ligase HQ2905A 218 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 110668397 Common - IS1341-type transposase HQ2485A 43 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668105 Common - hypothetical protein HQ2165A 72 COG1479 COG1479, Uncharacterized conserved protein Function unknown 110667259 Common leuA 2-isopropylmalate synthase HQ1292A 218 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 110669546 Common nosY ABC-type copper transport system, permease protein HQ3697A 52 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 110667027 Common pheT phenylalanyl-tRNA synthetase subunit beta HQ1050A 181 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 110669200 Common thrB homoserine kinase HQ3322A 117 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 110668436 Nonpathogen tbpE transcription factor HQ2527A 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 110668539 Nonpathogen - hypothetical protein HQ2633A 2 None None None 110668381 Common folP dihydropteroate synthase HQ2465A 215 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 110669453 Nonpathogen - hypothetical protein HQ3597A 3 None None None 110668208 Nonpathogen - hypothetical protein HQ2274A 1 None None None 110667003 Nonpathogen - hypothetical protein HQ1027A 21 COG2150 COG2150, Predicted regulator of amino acid metabolism, contains ACT domain General function prediction only 110667261 Nonpathogen - hypothetical protein HQ1294A 3 None None None 110668665 Common truB H/ACA RNA-protein complex component Cbf5p HQ2764A 236 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 110667707 Common - hypothetical protein HQ1753A 44 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 110668027 Nonpathogen - hypothetical protein HQ2082A 1 None None None 110667843 Nonpathogen - hypothetical protein HQ1889A 2 None None None 110669209 Common uppS di-trans,poly-cis-decaprenylcistransferase HQ3331A 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110667659 Nonpathogen - hypothetical protein HQ1702A 3 None None None 110669364 Nonpathogen - hypothetical protein HQ3501A 1 COG1753 COG1753, Uncharacterized conserved protein Function unknown 110668905 Nonpathogen - conserved acc operon protein HQ3017A 2 None None None 110669158 Common - adenine-specific DNA methyltransferase HQ3277A 41 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 110669077 Nonpathogen - hypothetical protein HQ3193A 4 None None None 110667239 Common aspC aspartyl-tRNA synthetase HQ1270A 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110669400 Common - hexosyltransferase; glycosyltransferase HQ3539A 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667388 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase HQ1426A 35 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 110668924 Nonpathogen cbiG cobalamin biosynthesis protein G, CbiG HQ3035A 12 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 110668058 Common - hypothetical protein HQ2113A 89 COG0433 COG0433, Predicted ATPase General function prediction only 110669422 Nonpathogen - hypothetical protein HQ3563A 2 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110666990 Nonpathogen bopI bacteriorhodopsin precursor (Squarebop I) HQ1014A 9 COG5524 COG5524, Bacteriorhodopsin General function prediction only 110668985 Nonpathogen - hypothetical protein HQ3099A 4 None None None 110667661 Nonpathogen - hypothetical protein HQ1704A 3 None None None 110667776 Nonpathogen - hypothetical protein HQ1821A 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667145 Nonpathogen - hypothetical protein HQ1171A 8 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 110669516 Common cbiQ ABC-type transport system permease protein (probable substrate cobalt) HQ3666A 30 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110667406 Common - predicted TRAP-type transport system, permease protein HQ1444A 103 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 110668131 Common livJ ABC-type branched-chain amino acid transport systems, substrate-binding protein HQ2192A 52 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110669070 Common livF ABC-type branched-chain amino acid transport systems, ATP_binding protein II HQ3186A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110668899 Common - hypothetical protein HQ3011A 85 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 110667059 Nonpathogen capC probable capsule polysaccharide biosynthesis protein, integral membrane protein HQ1083A 2 None None None 110667805 Common norM sodium-driven multidrug efflux pump HQ1850A 103 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110667223 Nonpathogen rps27e 30S ribosomal protein S27e HQ1254A 31 COG2051 RPS27A, Ribosomal protein S27E Translation, ribosomal structure and biogenesis 110667087 Nonpathogen - hypothetical protein HQ1112A 3 None None None 110666993 Common bopII bacteriorhodopsin precursor (Squarebop II) HQ1017A 12 COG5524 COG5524, Bacteriorhodopsin General function prediction only 110669521 Common rfcA replication factor C small subunit I HQ3671A 231 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 110667184 Nonpathogen - conserved hypothetical protein (probable surface protein) HQ1214A 20 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 110668286 Nonpathogen rps15p 30S ribosomal protein S15P HQ2361A 34 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 110669359 Common - hypothetical protein HQ3494A 3 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 110668595 Common - hexosyltransferase; glycosyltransferase HQ2691A 215 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667034 Common pncB nicotinate phosphoribosyltransferase HQ1058A 112 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 110668988 Common kefC probable potassium transport protein kefC HQ3102A 168 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 110668278 Common coxC cytochrome-c-like terminal oxidase, subunit III HQ2352A 153 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 110667241 Nonpathogen - hypothetical protein HQ1272A 30 COG1701 COG1701, Uncharacterized protein conserved in archaea Function unknown 110667527 Nonpathogen - transcription regulator HQ1568A 22 COG1497 COG1497, Predicted transcriptional regulator Transcription 110667942 Nonpathogen - ISH9-type transposase (nonfunctional, N-terminal part) HQ1993B 1 None None None 110667098 Common adh alcohol dehydrogenase HQ1124A 162 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110669298 Nonpathogen rpl39e 50S ribosomal protein L39e HQ3424A 12 COG2167 RPL39, Ribosomal protein L39E Translation, ribosomal structure and biogenesis 110667094 Common - probable ferredoxin-NAD+ reductase HQ1120A 242 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 110668262 Common ferA probable ferredoxin I HQ2336A 7 None None None 110669195 Common - hypothetical protein HQ3317A 78 COG1469 COG1469, Uncharacterized conserved protein Function unknown 110667107 Nonpathogen - hypothetical protein HQ1133A 1 None None None 110668491 Common metK S-adenosylmethionine synthetase HQ2584A 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 110669556 Nonpathogen - peroxiredoxin homolog HQ3707A 14 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110668688 Nonpathogen - hypothetical protein HQ2789A 3 None None None 110667221 Nonpathogen - hypothetical protein HQ1252A 3 None None None 110669124 Common atpB V-type ATP synthase subunit B HQ3243A 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 110667040 Nonpathogen - protein N-acetyltransferase homolog HQ1064A 7 COG0456 RimI, Acetyltransferases General function prediction only 110668549 Nonpathogen - homolog to acetyltransferases HQ2643A 4 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 110668690 Common glyA glycine hydroxymethyltransferase HQ2791A 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 110668039 Nonpathogen - hypothetical protein HQ2094A 1 None None None 110669175 Nonpathogen - hypothetical protein HQ3294A 1 None None None 110668670 Common ephA epoxide hydrolase-related protein HQ2769A 142 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110667739 Common cysE serine O-acetyltransferase HQ1785A 191 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 110667932 Nonpathogen - hypothetical protein HQ1984A 2 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 110669557 Common - probable DNA binding protein; probable translation factor HQ3708A 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 110667758 Nonpathogen - hypothetical protein HQ1804A 1 None None None 110667037 Common pyrC dihydroorotase HQ1061A 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110667762 Nonpathogen - hypothetical protein HQ1808A 20 COG1325 COG1325, Predicted exosome subunit Translation, ribosomal structure and biogenesis 110669194 Common - hypothetical protein HQ3316A 110 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 110667859 Nonpathogen - hypothetical protein HQ1907A 4 None None None 110668051 Nonpathogen - hypothetical protein HQ2106A 2 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 110667522 Common sirR transcription regulator SirR HQ1563A 70 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 110669382 Nonpathogen - probable transposase (ISH5) HQ3520A 3 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 110668713 Common - signal-transducing histidine kinase HQ2814A 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110667792 Common cbiQ CbiQ protein (probable ABC-type cobalt transport system permease protein 1) HQ1837A 60 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110668375 Nonpathogen - hypothetical protein HQ2459A 1 None None None 110668638 Nonpathogen - hypothetical protein HQ2737A 4 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 110668270 Common nqrF FAD/NAD binding oxidoreductase; probable Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF HQ2344A 10 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 110668765 Nonpathogen - hypothetical protein HQ2867A 7 COG4749 COG4749, Uncharacterized protein conserved in archaea Function unknown 110667112 Common - ABC-type multidrug/lipid transport system,permease and ATP-binding protein HQ1138A 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110667376 Nonpathogen - probable transcription regulator HQ1414A 9 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 110669162 Nonpathogen - hypothetical protein HQ3281A 2 None None None 110667144 Common - probable hydrolase HQ1170A 108 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110668617 Nonpathogen - hypothetical protein HQ2715A 1 None None None 110667176 Nonpathogen - hypothetical protein HQ1204A 1 None None None 110667937 Common ugpC ABC-type sugar/sn-glycerol-3-phosphate transport system, ATP-binding protein HQ1989A 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110667573 Nonpathogen trxA thioredoxin HQ1614A 2 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110668134 Common livG ABC-type branched-chain amino acid transport systems, ATP-binding protein I HQ2195A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110668307 Nonpathogen - hypothetical protein HQ2384A 4 None None None 110667938 Common ugpE ABC-type sugar/sn-glycerol-3-phosphate transport system, periplasmic protein HQ1990A 170 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110668030 Nonpathogen - hypothetical protein HQ2085A 1 None None None 110667730 Nonpathogen gvpG gas-vesicle operon protein gvpG HQ1776A 2 None None None 110667165 Common - probable dentin sialophosphoprotein precursor HQ1192A 2 None None None 110669287 Common trzA probable chlorohydrolase HQ3413A 173 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110668782 Nonpathogen rpl7ae 50S ribosomal protein L7Ae HQ2885A 34 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 110668887 Nonpathogen - hypothetical protein HQ2999A 4 None None None 110667381 Common kef Kef-type K+ transport systems, predicted NAD-binding component HQ1419A 77 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110669409 Nonpathogen - hypothetical protein HQ3548A 3 None None None 110668693 Nonpathogen - hypothetical protein HQ2794A 16 COG1967 COG1967, Predicted membrane protein Function unknown 110668919 Common - conserved cobalamin operon protein HQ3031A 7 None None None 110667633 Common phaG putative monovalent cation/H+ antiporter subunit G HQ1676A 96 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 110668425 Nonpathogen - hypothetical protein HQ2516A 1 None None None 110667348 Common ocd ornithine cyclodeaminase HQ1386A 97 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110667270 Common - hypothetical protein HQ1303A 5 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 110668045 Nonpathogen - hypothetical protein HQ2100A 1 None None None 110668538 Common ssuB ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; sulfonate ABC transporter ATP binding protein HQ2632A 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110668566 Common - hypothetical protein HQ2660A 20 None None None 110667074 Common moaE molybdopterin converting factor, large subunit HQ1099A 150 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 110668955 Nonpathogen - hypothetical protein HQ3068A 6 None None None 110668195 Common moxR MoxR-like ATPase HQ2259A 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 110667397 Common rpa replication factor A HQ1435A 30 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 110668362 Common trxB thioredoxin reductase homolog HQ2445A 108 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110667777 Common - probable alkaline phosphatase; probable cell surface glycoprotein HQ1822A 43 None None None 110669010 Nonpathogen - hypothetical protein HQ3124A 4 None None None 110667753 Common - Acetyltransferase, GNAT family HQ1799A 48 COG2153 ElaA, Predicted acyltransferase General function prediction only 110668283 Nonpathogen rps3aR 30S ribosomal protein S3Ae HQ2358A 34 COG1890 RPS1A, Ribosomal protein S3AE Translation, ribosomal structure and biogenesis 110668216 Common - hypothetical protein HQ2283A 3 None None None 110667485 Common mvaD diphosphomevalonate decarboxylase HQ1525A 23 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 110669303 Nonpathogen radA DNA repair and recombination protein RadA HQ3429A 34 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 110667818 Nonpathogen brp bop gene expression regulator HQ1864A 5 None None None 110668562 Common thiM hydroxyethylthiazole kinase HQ2656A 78 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 110667154 Common - glycosyltransferase homolog HQ1180A 36 None None None 110667519 Common gldA glycerol-1-phosphate dehydrogenase (NAD(P)) HQ1560A 73 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 110667699 Nonpathogen - IS1341-type transposase (nonfunctional,N-terminal part) HQ1744C 3 None None None 110669280 Common psd phosphatidylserine decarboxylase HQ3406A 90 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 110668221 Nonpathogen - hypothetical protein HQ2289A 2 None None None 110667016 Nonpathogen - hypothetical protein HQ1039A 2 None None None 110667457 Common - hypothetical protein HQ1496A 39 COG3428 COG3428, Predicted membrane protein Function unknown 110669574 Common uvrB excinuclease ABC subunit B HQ3725A 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 110667846 Nonpathogen - hypothetical protein HQ1893A 1 None None None 110667199 Nonpathogen padR transcription regulator HQ1230A 4 COG1695 COG1695, Predicted transcriptional regulators Transcription 110667469 Common dapB dihydrodipicolinate reductase HQ1508A 214 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 110667049 Common - signal-transducing histidine kinase; response regulator; PAS/PAC domain protein HQ1073A 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110667973 Common - PHP domain protein HQ2026A 114 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110668000 Nonpathogen - hypothetical protein HQ2055A 1 None None None 110669499 Nonpathogen - hypothetical protein HQ3649A 4 None None None 110667996 Common - IS1341-type transposase HQ2051A 54 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667024 Nonpathogen endA tRNA splicing endonuclease HQ1047A 29 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 110669464 Nonpathogen - hypothetical protein HQ3610A 4 None None None 110669539 Nonpathogen - probable transporter HQ3689A 1 None None None 110667410 Nonpathogen adkA adenylate kinase HQ1449A 23 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 110669550 Common - major facilitator superfamily transporter HQ3701A 102 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110667692 Common phoU phosphate transport operon regulator HQ1737A 190 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110667510 Common petD menaquinol--cytochrome-c reductase (cytochrome bc complex) cytochrome b/c subunit HQ1551A 10 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 110667247 Common - signal-transducing histidine kinase; response regulator; PAS/PAC domain protein HQ1280A 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110668331 Nonpathogen - hypothetical protein HQ2409A 3 COG2259 COG2259, Predicted membrane protein Function unknown 110667959 Common uvsE putative UV damage endonuclease HQ2011A 22 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 110668627 Common msc probable mechanosensitive ion channel HQ2725A 219 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110668153 Nonpathogen - hypothetical protein HQ2215A 1 None None None 110668879 Nonpathogen - hypothetical protein HQ2991A 1 None None None 110668664 Common pheA chorismate mutase HQ2763A 37 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 110667086 Nonpathogen - hypothetical protein HQ1111A 1 None None None 110668844 Nonpathogen - hypothetical protein HQ2951A 2 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110668620 Nonpathogen - conserved primase operon protein HQ2718A 5 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 110668550 Nonpathogen - hypothetical protein HQ2644A 3 None None None 110667858 Nonpathogen - hypothetical protein HQ1906A 3 None None None 110668979 Common - ABC-type transport system, ATP-binding protein HQ3093A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110667876 Nonpathogen - hypothetical protein HQ1925A 1 None None None 110669103 Nonpathogen - hypothetical protein HQ3220A 2 None None None 110668963 Nonpathogen - hypothetical protein HQ3076A 30 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 110668316 Nonpathogen - hypothetical protein HQ2393A 4 None None None 110667355 Common hsp20 hsp20 type chaperone HQ1393A 27 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110667353 Nonpathogen rpl10e 50S ribosomal protein L10e HQ1391A 34 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 110667427 Common psp ribonuclease, PSP-type; translation intitiation inhibition protein HQ1466A 148 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110668796 Nonpathogen - Predicted Zn-ribbon RNA-binding protein HQ2899A 27 COG2888 COG2888, Predicted Zn-ribbon RNA-binding protein with a function in translation Translation, ribosomal structure and biogenesis 110667628 Nonpathogen - hypothetical protein HQ1671A 13 COG3357 COG3357, Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon Transcription 110668836 Common rps4p 30S ribosomal protein S4 HQ2943A 121 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 110668559 Common top6B DNA topoisomerase VI subunit B HQ2653A 35 COG1389 COG1389, DNA topoisomerase VI, subunit B DNA replication, recombination, and repair 110669580 Nonpathogen - hypothetical protein HQ3732A 1 None None None 110668267 Common - predicted sugar kinase HQ2341A 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 110668521 Common xerC tyrosine recombinase xerC HQ2614A 81 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110669393 Nonpathogen - hypothetical protein HQ3531A 1 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110668005 Nonpathogen - hypothetical protein HQ2060A 1 None None None 110669435 Nonpathogen - hypothetical protein HQ3578A 3 COG2886 COG2886, Uncharacterized small protein Function unknown 110667611 Nonpathogen - hypothetical protein HQ1653A 17 COG1849 COG1849, Uncharacterized protein conserved in archaea Function unknown 110668444 Common - hypothetical protein HQ2535A 6 None None None 110667886 Common pyrC dihydroorotase HQ1936A 203 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110667058 Common capB capsular biosynthesis protein CapB / polyglutamate synthase HQ1082A 12 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 110668257 Nonpathogen - hypothetical protein HQ2331A 2 None None None 110668500 Nonpathogen phoU phosphate uptake regulator / ABC transport system regulatory protein HQ2593A 30 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110668744 Nonpathogen - hypothetical protein HQ2845A 2 COG1624 COG1624, Uncharacterized conserved protein Function unknown 110669445 Nonpathogen - hypothetical protein HQ3589A 1 None None None 110668167 Nonpathogen - hypothetical protein HQ2229A 1 None None None 110667870 Common speE spermidine synthase HQ1919A 57 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 110669338 Nonpathogen - probable cell surface glycoprotein HQ3468A 2 None None None 110668703 Nonpathogen - hypothetical protein HQ2804A 4 None None None 110667548 Nonpathogen - hypothetical protein HQ1589A 4 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 110669299 Common - tetratricopeptide repeat protein HQ3425A 57 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 110668956 Nonpathogen - hypothetical protein HQ3069A 4 None None None 110668929 Common - hypothetical protein HQ3040A 45 COG0628 PerM, Predicted permease General function prediction only 110667214 Common aroE shikimate 5-dehydrogenase HQ1245A 222 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110667924 Common tauC ABC-type nitrate/sulfonate/bicarbonate transport system, permease protein HQ1975A 76 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110668572 Nonpathogen - hypothetical protein HQ2666A 2 None None None 110669015 Common purU formyltetrahydrofolate deformylase HQ3129A 224 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 110668152 Nonpathogen - hypothetical protein HQ2214A 3 None None None 110668028 Nonpathogen - probable haloviral protein HQ2083A 1 None None None 110666980 Nonpathogen - hypothetical protein HQ1004A 4 None None None 110667433 Nonpathogen - halobacterial transducer protein homolog HQ1472A 1 None None None 110668125 Common dctP TRAP-type C4-dicarboxylate transport system,periplasmic component DctP (YiaO) HQ2186A 94 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110667170 Common hmu2 cell surface glycoprotein HQ1197A 100 COG3889 COG3889, Predicted solute binding protein General function prediction only 110669215 Nonpathogen - hypothetical protein HQ3339A 2 None None None 110668817 Common celM probable cellulase; probable endo-1,3(4)-beta-glucanase HQ2923A 75 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 110669278 Nonpathogen - hypothetical protein HQ3404A 2 None None None 110669271 Nonpathogen rpoH DNA-directed RNA polymerase subunit H HQ3397A 32 COG2012 RPB5, DNA-directed RNA polymerase, subunit H, RpoH/RPB5 Transcription 110668394 Common mutY A/G-specific adenine glycosylase HQ2481A 226 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 110667367 Common cobO cob(I)alamin adenosyltransferase HQ1405A 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 110668653 Common lhr Lhr-like helicase HQ2752A 237 COG1201 Lhr, Lhr-like helicases General function prediction only 110667177 Common - probable cell surface adhesin HQ1205A 143 None None None 110667967 Common salY ABC-type antimicrobial peptide transport system,permease protein HQ2019A 161 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110669459 Nonpathogen - hypothetical protein HQ3603A 2 None None None 110668160 Common - hypothetical protein HQ2222A 7 COG0392 COG0392, Predicted integral membrane protein Function unknown 110667912 Nonpathogen - hypothetical protein HQ1962A 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110668791 Nonpathogen - hypothetical protein HQ2894A 33 COG1491 COG1491, Predicted RNA-binding protein Translation, ribosomal structure and biogenesis 110667039 Common usp homolog to stress response protein HQ1063A 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667840 Common mtfK1 FKBP-type peptidylprolyl isomerase 1 HQ1886A 117 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 110669562 Nonpathogen - arg cluster protein HQ3713A 1 None None None 110667138 Common nadR nicotinamide-nucleotide adenylyltransferase HQ1164A 44 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 110667092 Common lrp transcription regulator HQ1118A 96 COG1522 Lrp, Transcriptional regulators Transcription 110669192 Nonpathogen - hypothetical protein HQ3314A 1 None None None 110669263 Nonpathogen - hypothetical protein HQ3389A 4 None None None 110669114 Nonpathogen - hypothetical protein HQ3232A 2 None None None 110669255 Common potB ABC-type spermidine/putrescine transport system,permease protein I HQ3381A 175 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110669549 Common metA homoserine O-acetyltransferase HQ3700A 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 110667772 Nonpathogen - hypothetical protein HQ1817A 1 None None None 110668296 Common - regulatory protein PrrC HQ2373A 35 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 110667461 Common - hypothetical protein HQ1500A 20 COG3361 COG3361, Uncharacterized conserved protein Function unknown 110669415 Nonpathogen - probable transposase (ISH8/ISH26) HQ3554A 3 None None None 110667133 Common trpC indole-3-glycerol-phosphate synthase HQ1159A 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 110668018 Nonpathogen - hypothetical protein HQ2073A 1 None None None 110668742 Nonpathogen - conserved rpl operon protein HQ2843A 20 COG2106 COG2106, Uncharacterized conserved protein Function unknown 110667506 Nonpathogen - hypothetical protein HQ1547A 3 COG1422 COG1422, Predicted membrane protein Function unknown 110669213 Common cysG siroheme synthase (precorrin-2 oxidase and ferrochelatase) (N-terminal domain homology to multifunctional siroheme synthase CysG of Escherichia coli) HQ3335A 107 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 110668384 Common gatE glutamyl-tRNA(Gln) amidotransferase subunit E HQ2468A 195 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 110668527 Common nuoL homolog to NADH dehydrogenase, subunit L (ubiquinone) HQ2621A 203 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 110667065 Nonpathogen - hypothetical protein HQ1090A 3 None None None 110668068 Nonpathogen - hypothetical protein HQ2125A 1 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 110668275 Nonpathogen - hypothetical protein HQ2349A 4 COG3427 COG3427, Uncharacterized conserved protein Function unknown 110668289 Common dapA dihydrodipicolinate synthase HQ2365A 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110667856 Nonpathogen - hypothetical protein HQ1904A 3 None None None 110667804 Nonpathogen - hypothetical protein HQ1849A 1 None None None 110668416 Common norM sodium-driven multidrug efflux pump HQ2506A 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110668357 Common - transporter of the drug/metabolite transporter (DMT) superfamily HQ2440A 62 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 110669577 Nonpathogen - conserved flagella cluster protein (probable integral membrane protein) HQ3728A 2 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 110667529 Common ppsA1 phosphoenolpyruvate synthase HQ1570A 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 110667535 Nonpathogen - hypothetical protein HQ1576A 4 None None None 110667866 Nonpathogen ski probable two-component system sensor kinase HQ1914A 3 None None None 110668906 Common accA acetyl-CoA carboxylase alpha subunit HQ3018A 201 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 110667653 Nonpathogen rpoL DNA-directed RNA polymerase subunit L HQ1696A 10 COG1761 RPB11, DNA-directed RNA polymerase, subunit L Transcription 110667667 Common sirR transcription regulator SirR HQ1710A 65 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 110669367 Nonpathogen - hypothetical protein HQ3505A 2 None None None 110669517 Nonpathogen ferB ferredoxin II HQ3667A 26 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 110667129 Common aroB 3-dehydroquinate synthase HQ1155A 28 COG1465 COG1465, Predicted alternative 3-dehydroquinate synthase Amino acid transport and metabolism 110668461 Nonpathogen - hypothetical protein HQ2552A 2 None None None 110667723 Common psp ribonuclease, PSP-type HQ1769A 179 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110668983 Common secD preprotein translocase subunit SecD HQ3097A 135 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 110668056 Nonpathogen - hypothetical protein HQ2111A 2 None None None 110667185 Common - RND superfamily exporter HQ1215A 62 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 110669346 Common lolD ABC-type transport system, ATP-binding protein similar to LolDE lipoprotein release factor HQ3478A 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110668830 Nonpathogen rpoN DNA-directed RNA polymerase subunit N HQ2937A 34 COG1644 RPB10, DNA-directed RNA polymerase, subunit N (RpoN/RPB10) Transcription 110666987 Common aaa3 AAA-type ATPase (transitional ATPase homolog) HQ1011A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110668937 Common thsA thermosome, alpha subunit HQ3049A 238 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110667584 Nonpathogen tfbA transcription initiation factor TFB HQ1625A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667626 Common - hypothetical protein HQ1669A 49 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 110668232 Common mcmB methylmalonyl-CoA mutase, subunit B (cobalamin-binding subunit) HQ2301A 114 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 110669083 Nonpathogen moaD molybdopterin converting factor, small subunit HQ3199A 8 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 110668881 Nonpathogen - hypothetical protein HQ2993A 1 None None None 110668119 Nonpathogen - hypothetical protein HQ2180A 4 None None None 110668246 Nonpathogen - hypothetical protein HQ2316A 15 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110667378 Nonpathogen - S-adenosylmethionine-dependent methyltransferase HQ1416A 20 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110668437 Common rhl DNA repair helicase HQ2528A 105 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 110667459 Nonpathogen - hypothetical protein HQ1498A 1 None None None 110669321 Common hemC hydroxymethylbilane synthase (porphobilinogen deaminase) HQ3450A 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 110667905 Common - sodium/anion symporter (probable sulfate or citrate) HQ1955A 127 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 110666978 Nonpathogen sec11 signal sequence peptidase HQ1002A 15 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110668430 Common - major facilitator superfamily transporter (probable quinolone resistance protein) HQ2521A 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110668772 Nonpathogen - probable transcriptional regulator HQ2874A 5 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 110668265 Common hflX GTP-binding protein HQ2339A 211 COG2262 HflX, GTPases General function prediction only 110668607 Common leuC isopropylmalate isomerase large subunit HQ2705A 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 110668629 Nonpathogen - hypothetical protein HQ2727A 2 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 110668642 Common - hypothetical protein HQ2741A 24 COG3358 COG3358, Uncharacterized conserved protein Function unknown 110668733 Nonpathogen rnpA Ribonuclease P protein component 1 (RNase P component 1) HQ2834A 8 COG1588 POP4, RNase P/RNase MRP subunit p29 Translation, ribosomal structure and biogenesis 110669199 Common hemY hypothetical protein HQ3321A 28 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 110668454 Common sfuA ABC-type iron(III) transport system,substrate-binding protein HQ2545A 104 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110667030 Nonpathogen - hypothetical protein HQ1053A 3 None None None 110669474 Nonpathogen cbiQ ABC-type cobalt transport system, permease protein HQ3623A 31 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110669122 Nonpathogen erf1 peptide chain release factor 1 HQ3241A 34 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 110668622 Common hisD histidinol dehydrogenase HQ2720A 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 110667383 Common cysA ABC-type transport system, ATP-binding domain (probable substrates sulfate, thiosulfate or molybdate) HQ1421A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110667106 Common fdhA NADH:ubiquinone oxidoreductase / formate dehydrogenase, alpha subunit HQ1132A 193 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110669034 Nonpathogen - hypothetical protein HQ3149A 19 COG1920 COG1920, Uncharacterized conserved protein Function unknown 110668600 Nonpathogen - hypothetical protein HQ2697A 3 None None None 110669136 Common idsA probable multifunctional long-chain (E)-prenyl diphosphate synthase HQ3255A 216 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 110667320 Common pimT protein-L-isoaspartate O-methyltransferase HQ1357A 113 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 110668610 Common hpr phosphocarrier protein Hpr HQ2708A 129 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 110668209 Common dap2 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases HQ2276A 164 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 110667147 Nonpathogen - predicted Fe-S oxidoreductase HQ1173A 27 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 110667565 Nonpathogen - hypothetical protein HQ1606A 2 None None None 110668592 Common - probable polysaccharide biosynthesis transport protein HQ2687A 79 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110668439 Nonpathogen - hypothetical protein HQ2530A 2 None None None 110667253 Nonpathogen pfdB prefoldin beta subunit HQ1286A 28 COG1382 GimC, Prefoldin, chaperonin cofactor Posttranslational modification, protein turnover, chaperones 110668029 Nonpathogen - hypothetical protein HQ2084A 1 None None None 110669154 Nonpathogen - hypothetical protein HQ3273A 2 None None None 110667399 Common aup histone deacetylase HQ1437A 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 110667325 Nonpathogen - hypothetical protein HQ1362A 1 None None None 110667057 Common hmu halomucin HQ1081A 159 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110668922 Common cbiH2 precorrin-3B C17-methyltransferase 2 HQ3033A 181 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 110668730 Nonpathogen rpl24p 50S ribosomal protein L24P HQ2831A 34 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 110667345 Common phnD ABC-type phosphate/phosphonate/phosphite transport system, substrate-binding protein HQ1383A 23 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 110667749 Common tdk thymidine kinase HQ1795A 69 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 110668047 Nonpathogen - hypothetical protein HQ2102A 1 None None None 110667062 Nonpathogen - hypothetical protein HQ1086A 3 None None None 110667976 Common cad pterin-4a-carbinolamine dehydratase HQ2029A 86 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 110668096 Nonpathogen - transcriptional regulator HQ2155A 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110669225 Common surE acid phosphatase HQ3350A 185 COG0496 SurE, Predicted acid phosphatase General function prediction only 110667490 Common - hypothetical protein HQ1530A 39 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 110669064 Common vacB ribonuclease R homolog HQ3180A 192 COG0557 VacB, Exoribonuclease R Transcription 110669243 Common - hypothetical protein HQ3368A 92 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110667613 Nonpathogen - hypothetical protein HQ1655A 3 None None None 110667647 Common - mut/nudix family protein HQ1690A 12 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110667119 Common nosF ABC-type copper transport system involved in multi-copper enzyme maturation, ATP-binding protein HQ1145A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110669388 Nonpathogen - ISH9-type transposase (nonfunctional, C-terminal part) HQ3527A 5 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 110668472 Common - hypothetical protein HQ2563A 27 COG1624 COG1624, Uncharacterized conserved protein Function unknown 110667608 Common - CBS domain protein / probable chromosome partitioning protein HQ1650A 119 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 110669373 Nonpathogen - hypothetical protein HQ3511A 3 None None None 110668171 Common cat probable cationic amino acid transport protein HQ2233A 105 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110669312 Nonpathogen - hypothetical protein HQ3440A 3 None None None 110667445 Common dppC ABC-type dipeptide/oligopeptide/nickel transport system, permease protein II HQ1484A 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110668672 Common - 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase) HQ2771A 227 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110669096 Common icd isocitrate dehydrogenase (NADP+) HQ3212A 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 110668295 Common uspA probable stress response protein HQ2372A 93 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110669504 Nonpathogen tfbA transcription initiation factor TFB HQ3654A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667499 Common - conserved hypothetical protein (probable surface protein) HQ1540A 27 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 110667951 Nonpathogen - hypothetical protein HQ2002A 4 None None None 110668015 Nonpathogen - hypothetical protein HQ2070A 1 None None None 110667551 Common trxB thioredoxin reductase (NADPH) HQ1592A 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110669371 Common galE nucleoside-diphosphate-sugar epimerase (probable UDP-glucose 4-epimerase) HQ3509A 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110667497 Common acs acyl-CoA synthetase I HQ1538A 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 110667336 Nonpathogen - archaemetzincin-like protein HQ1374A 30 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 110668894 Nonpathogen - hypothetical protein HQ3006A 5 COG1547 COG1547, Uncharacterized conserved protein Function unknown 110668479 Nonpathogen tfbA transcription initiation factor TFB HQ2571A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667715 Common gcvT aminomethyltransferase, glycin cleavage system T protein HQ1761A 183 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 110667263 Nonpathogen - ABC-type transport system, permease protein HQ1296A 9 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 110669031 Common nolA NADH dehydrogenase 32K chain HQ3146A 168 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110667277 Common dppA ABC-type dipeptide/oligopeptide/nickel transport system, substrate binding protein HQ1310A 163 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110668469 Common purD phosphoribosylamine--glycine ligase HQ2560A 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 110669233 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase HQ3358A 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 110667042 Common usp probable stress response protein HQ1066A 126 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667128 Common aroD 3-dehydroquinate dehydratase HQ1154A 53 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 110669065 Nonpathogen - hypothetical protein HQ3181A 4 None None None 110668873 Common sqdB UDP-sulfoquinovose synthase HQ2984A 125 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110668350 Common arsA transport ATPase (probable substrate arsenite) HQ2430A 95 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 110667941 Common - transcription regulator HQ1993A 121 COG1414 IclR, Transcriptional regulator Transcription 110669428 Nonpathogen - hypothetical protein HQ3571A 4 None None None 110668726 Common rps8p 30S ribosomal protein S8P HQ2827A 173 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 110668816 Common rpl11p 50S ribosomal protein L11P HQ2922A 231 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 110667794 Nonpathogen - hypothetical protein HQ1839A 1 None None None 110668599 Nonpathogen - hypothetical protein HQ2696A 6 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 110669051 Common trpG anthranilate synthase, component II HQ3166A 226 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 110669146 Nonpathogen - hypothetical protein HQ3265A 4 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 110668418 Common - LPS glycosyltransferase HQ2508A 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667201 Nonpathogen - hypothetical protein HQ1232A 1 None None None 110667589 Nonpathogen - hypothetical protein HQ1630A 1 None None None 110668982 Common rnhB ribonuclease HII HQ3096A 48 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 110668489 Nonpathogen - hypothetical protein HQ2582A 14 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110668775 Common ksgA dimethyladenosine transferase HQ2878A 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 110667827 Common menD 2-oxoglutarate decarboxylase; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase HQ1873A 129 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 110668408 Common iunH Inosine-uridine preferring nucleoside hydrolase HQ2498A 83 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 110667233 Common smc chromosome partition protein HQ1264A 209 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110668862 Common livJ ABC-type branched-chain amino acid transport systems, substrate-binding protein HQ2969A 97 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110669075 Common ghmP GHMP family kinase HQ3191A 29 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 110667740 Common - ABC-type transport system ATP-binding protein HQ1786A 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110669256 Common potA ABC-type spermidine/putrescine transport system,ATP-binding protein HQ3382A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110668011 Common serA phosphoglycerate dehydrogenase HQ2066A 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110667635 Common phaB2 putative monovalent cation/H+ antiporter subunit B HQ1678A 9 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 110668516 Common arsA probable arsenite efflux ATPase HQ2609A 96 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 110668995 Nonpathogen - hypothetical protein HQ3109A 4 None None None 110667597 Common nuoB NADH dehydrogenase, subunit B (ubiquinone) HQ1638A 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 110668127 Nonpathogen - hypothetical protein HQ2188A 1 None None None 110667785 Nonpathogen - conserved cobalamin operon protein HQ1830A 4 COG1141 Fer, Ferredoxin Energy production and conversion 110668107 Nonpathogen - hypothetical protein HQ2168A 2 None None None 110667404 Common Imp predicted TRAP-type transport system,periplasmic protein HQ1442A 85 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 110667520 Common lysE LysE family L-lysine efflux protein/ threonine/homoserine/homoserine lactone efflux protein HQ1561A 48 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110669028 Common trkA TrkA-domain protein (NAD-binding protein) HQ3143A 157 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110669189 Common carB carbamoyl phosphate synthase large subunit HQ3311A 233 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 110668088 Nonpathogen - hypothetical protein HQ2147A 2 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110668751 Common nif3 hypothetical protein HQ2853A 99 COG0327 COG0327, Uncharacterized conserved protein Function unknown 110667650 Common purL phosphoribosylformylglycinamidine synthase, component II HQ1693A 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 110667593 Nonpathogen - conserved purK operon protein / membrane-bound mannosyltransferase HQ1634A 12 COG4745 COG4745, Predicted membrane-bound mannosyltransferase Posttranslational modification, protein turnover, chaperones 110668040 Nonpathogen - hypothetical protein HQ2095A 1 None None None 110667212 Common ftsZ cell division protein FtsZ HQ1243A 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 110667751 Nonpathogen - RecJ-like exonuclease HQ1797A 21 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 110668411 Nonpathogen rnp4 ribonuclease P protein component 4 HQ2501A 23 COG2023 RPR2, RNase P subunit RPR2 Translation, ribosomal structure and biogenesis 110669407 Nonpathogen - hypothetical protein HQ3546A 1 None None None 110669413 Common - ISH4-type transposase HQ3552A 6 None None None 110668568 Nonpathogen - hypothetical protein HQ2662A 1 None None None 110669493 Common glnA glutamate--ammonia ligase HQ3643A 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 110668032 Common - probable helicase family protein HQ2087A 26 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110668908 Common bcp peroxiredoxin homolog, bacterioferritin comigrating protein HQ3020A 218 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110667412 Common focA probable formate/nitrite transport protein HQ1451A 33 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 110669357 Nonpathogen - transcription regulator HQ3491A 3 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110667515 Nonpathogen - hypothetical protein HQ1556A 6 COG4746 COG4746, Uncharacterized protein conserved in archaea Function unknown 110669398 Nonpathogen - hypothetical protein HQ3537A 2 None None None 110667631 Common phaE putative monovalent cation/H+ antiporter subunit E HQ1674A 48 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 110668854 Common - protein N-acetyltransferase homolog HQ2961A 23 COG0456 RimI, Acetyltransferases General function prediction only 110667156 Common - sugar epimerase/dehydratase homolog HQ1183A 113 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110668953 Common - probable metalloprotease/ CBS domain protein HQ3066A 141 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110669012 Nonpathogen - hypothetical protein HQ3126A 4 None None None 110667756 Nonpathogen pelA cell division protein pelota HQ1802A 34 COG1537 PelA, Predicted RNA-binding proteins General function prediction only 110668564 Nonpathogen - hypothetical protein HQ2658A 28 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110668197 Nonpathogen - hypothetical protein HQ2261A 1 None None None 110668691 Nonpathogen - hypothetical protein HQ2792A 5 None None None 110668901 Common - tRNA-dihydrouridine synthase HQ3013A 26 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110667197 Nonpathogen tfbA transcription initiation factor TFB HQ1227A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110669462 Nonpathogen - hypothetical protein HQ3606A 2 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 110669205 Nonpathogen - hypothetical protein HQ3327A 4 None None None 110667971 Common ppsA2 pyruvate, water dikinase (phosphoenolpyruvate synthase) HQ2024A 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 110667275 Common dppC ABC-type dipeptide/oligopeptide/nickel transport system, permease protein II HQ1308A 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110668386 Common bolA probable BolA-like protein HQ2473A 84 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 110667517 Common - hexosyltransferase; glycosyltransferase HQ1558A 41 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110668880 Common graD glucose-1-phosphate thymidylyltransferase HQ2992A 241 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 110668144 Nonpathogen - hypothetical protein HQ2206A 3 None None None 110668587 Nonpathogen stt3 transmembrane oligosaccharyl transferase HQ2681A 13 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 110667816 Common nifS probable cysteine desulfurase, class V aminotransferase HQ1862A 235 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110667343 Common phnE ABC-type phosphate/phosphonate/phosphite transport system, permease protein HQ1381A 101 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 110668579 Common dhaK2 dihydroxyacetone kinase HQ2673A 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 110668842 Common mrp ATP-binding protein Mrp HQ2949A 233 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110667190 Common polIVx DNA-directed DNA polymerase (family X) / ycdX protein homolog HQ1220A 68 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 110669177 Common - AAA-type ATPase (cell division control protein homolog) HQ3297A 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 110667737 Common trpG anthranilate synthase component II HQ1783A 229 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 110667023 Common mer3 ATP-dependent DNA helicase HQ1046A 144 COG1204 COG1204, Superfamily II helicase General function prediction only 110669128 Nonpathogen atpE V-type ATP synthase subunit E HQ3247A 15 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 110668763 Nonpathogen - hypothetical protein HQ2865A 15 COG1432 COG1432, Uncharacterized conserved protein Function unknown 110666998 Common hisI phosphoribosyl-AMP cyclohydrolase HQ1022A 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 110668166 Common - hypothetical protein HQ2228A 105 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110667472 Common dapF diaminopimelate epimerase (DAP epimerase) HQ1511A 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 110667954 Nonpathogen - hypothetical protein HQ2005A 4 None None None 110669184 Nonpathogen - hypothetical protein HQ3306A 3 None None None 110669101 Common nadB L-aspartate oxidase, quinolinate synthetase subunit B HQ3217A 223 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 110668244 Nonpathogen - hypothetical protein HQ2313A 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110668090 Common uvrD DNA helicase II HQ2149A 229 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 110668651 Common bat Bacterio-opsin like activator / GAF, PAS/PAC domain protein HQ2750A 12 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110667524 Common crtI phytoene dehydrogenase (phytoene desaturase) HQ1565A 20 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110668110 Nonpathogen - hypothetical protein HQ2171A 3 None None None 110668215 Nonpathogen - hypothetical protein HQ2282A 3 None None None 110667174 Nonpathogen - hypothetical protein HQ1202A 1 None None None 110667703 Common - hypothetical protein HQ1749A 111 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 110669384 Nonpathogen - hypothetical protein HQ3522A 4 None None None 110669289 Common - sulfatase HQ3415A 62 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110667826 Common menF isochorismate synthase HQ1872A 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110667830 Common menC O-succinylbenzoate-CoA synthase (OSB synthase; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase) HQ1876A 129 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110667351 Nonpathogen - hypothetical protein HQ1389A 2 COG5652 COG5652, Predicted integral membrane protein Function unknown 110668757 Common nrdA ribonucleoside-diphosphate reductase alpha subunit (intein-containing) HQ2859A 189 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 110669085 Common udp uridine phosphorylase HQ3201A 108 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 110668255 Common glpG rhomboid family protein HQ2329A 21 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110668132 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ2193A 214 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667575 Common livG ABC-type branched-chain amino acid transport systems, ATP-binding protein I HQ1616A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667945 Common - Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain HQ1996A 131 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 110669040 Nonpathogen - hypothetical protein HQ3155A 1 None None None 110668301 Nonpathogen - hypothetical protein HQ2378A 3 None None None 110669584 Nonpathogen - hypothetical protein HQ3736A 10 COG3364 COG3364, Zn-ribbon containing protein General function prediction only 110667553 Nonpathogen - hypothetical protein HQ1594A 2 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 110667425 Common purT phosphoribosylglycinamide formyltransferase 2; formate-dependent GAR transformylase HQ1464A 201 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 110667072 Common lysS lysine--tRNA ligase HQ1097A 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 110668933 Common - transporter of the drug/metabolite transporter (DMT) superfamily HQ3044A 132 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110667895 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A HQ1945A 100 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 110668260 Common nce Na+/Ca2+-antiporter HQ2334A 118 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 110668779 Common ndk nucleoside-diphosphate kinase HQ2882A 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 110668432 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase (Phosphatidylserine synthase) HQ2523A 20 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110667051 Common gnd 6-phosphogluconate dehydrogenase-like protein HQ1075A 183 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 110669336 Nonpathogen - hypothetical protein HQ3466A 4 None None None 110668392 Nonpathogen - hypothetical protein HQ2479A 4 None None None 110669433 Nonpathogen - hypothetical protein HQ3576A 1 None None None 110668352 Nonpathogen rnhA ribonuclease H I HQ2432A 4 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 110667540 Nonpathogen - RecJ like exonuclease HQ1581A 21 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 110669132 Common menG menaquinone biosynthesis methyltransferase homolog HQ3251A 193 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110669326 Common pitA probable phosphate permease HQ3455A 106 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 110667369 Common cobD L-threonine-O-3-phosphate decarboxylase HQ1407A 221 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110667872 Common - hypothetical protein HQ1921A 14 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110668794 Nonpathogen - hypothetical protein HQ2897A 1 None None None 110668872 Nonpathogen - hypothetical protein HQ2983A 1 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 110667415 Nonpathogen - hypothetical protein HQ1454A 3 COG3431 COG3431, Predicted membrane protein Function unknown 110669023 Common serS seryl-tRNA synthetase HQ3138A 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 110668480 Nonpathogen - hypothetical protein HQ2572A 1 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 110669119 Common - IS1341-type transposase HQ3237A 76 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668285 Nonpathogen - conserved rps operon protein HQ2360A 4 None None None 110669560 Common argG argininosuccinate synthase HQ3711A 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 110667360 Nonpathogen - probable ribonuclease (G/E family) HQ1398A 16 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 110668207 Nonpathogen - hypothetical protein HQ2273A 3 None None None 110667969 Common uspA universal stress protein HQ2022A 62 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110668341 Nonpathogen - IS1341-type transposase HQ2419A 3 None None None 110669292 Common srp54 signal recognition particle 54K protein HQ3418A 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 110667362 Nonpathogen - hypothetical protein HQ1400A 1 None None None 110669054 Common trpD anthranilate phosphoribosyltransferase HQ3169A 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 110667228 Common phfZ probable phenazine biosynthesis protein HQ1259A 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 110668502 Common pat acetyltransferase protein (conserved in phopsphonate uptake operon) HQ2595A 183 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110668552 Common cdd cytidine deaminase HQ2646A 108 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 110668910 Common moaB molybdenum cofactor biosynthesis protein B HQ3022A 102 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 110667084 Nonpathogen - hypothetical protein HQ1109A 2 None None None 110667985 Common cysA thiosulfate sulfurtransferase HQ2038A 139 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110667439 Common dppD ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein I HQ1478A 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110669582 Nonpathogen - hypothetical protein HQ3734A 6 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 110667695 Nonpathogen - probable transcription regulator HQ1740A 4 COG1378 COG1378, Predicted transcriptional regulators Transcription 110668931 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B HQ3042A 89 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 110668821 Common elaC Ribonuclease Z (RNase Z) (tRNA 3 endonuclease) HQ2927A 126 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 110667878 Nonpathogen - IS1341-type transposase (nonfunctional,N-terminal part) HQ1927A 6 None None None 110668716 Nonpathogen - hypothetical protein HQ2817A 1 None None None 110669276 Nonpathogen - hypothetical protein HQ3402A 26 COG2433 COG2433, Uncharacterized conserved protein Function unknown 110668159 Common nikR putative nickel responsive regulator HQ2221A 62 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 110667538 Common taqD glycerol-3-phosphate cytidyltransferase homolog HQ1579A 51 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 110668474 Nonpathogen ppaT phosphopantetheine adenylyltransferase HQ2565A 27 COG1019 COG1019, Predicted nucleotidyltransferase General function prediction only 110668834 Nonpathogen rpoD DNA-directed RNA polymerase subunit D HQ2941A 34 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 110667674 Nonpathogen - IS1341-type transposase (nonfunctional,N-terminal part) HQ1717H 1 None None None 110667079 Nonpathogen rps19R 30S ribosomal protein S19e HQ1104A 34 COG2238 RPS19A, Ribosomal protein S19E (S16A) Translation, ribosomal structure and biogenesis 110666991 Nonpathogen - hypothetical protein HQ1015A 3 None None None 110667988 Common cinA CinA-like domain protein HQ2043A 140 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 110668318 Nonpathogen rpoM1 DNA-directed RNA polymerase subunit M1 HQ2396A 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 110668333 Nonpathogen - hypothetical protein HQ2411A 3 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110667533 Nonpathogen - hypothetical protein HQ1574A 1 None None None 110667648 Common asnB asparagine synthase (glutamine-hydrolyzing) HQ1691A 66 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 110668269 Nonpathogen - hypothetical protein HQ2343A 3 None None None 110667163 Common virB11 type II/IV secretion system proteins VirB11/TadA (predicted ATPase) HQ1190A 111 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 110667641 Nonpathogen - hypothetical protein HQ1684A 3 COG5637 COG5637, Predicted integral membrane protein Function unknown 110668640 Nonpathogen - hypothetical protein HQ2739A 2 None None None 110667693 Nonpathogen - hypothetical protein HQ1738A 2 None None None 110667255 Nonpathogen - hypothetical protein HQ1288A 21 COG3356 COG3356, Predicted membrane protein Function unknown 110668079 Nonpathogen - hypothetical protein HQ2136A 2 None None None 110667250 Nonpathogen rpl37aR ribosomal protein L37a.eR HQ1283A 6 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 110668606 Common ilvC ketol-acid reductoisomerase HQ2704A 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 110667290 Nonpathogen rpl40e 50S ribosomal protein L40e HQ1324A 24 COG1552 RPL40A, Ribosomal protein L40E Translation, ribosomal structure and biogenesis 110667297 Nonpathogen - hypothetical protein HQ1332A 4 None None None 110667450 Common dpg probable dolichyl-phosphate beta-glucosyltransferase (only N-terminal homology) HQ1489A 187 COG0392 COG0392, Predicted integral membrane protein Function unknown 110668234 Common cbiO ABC-type cobalt transport system, ATP-binding protein HQ2303A 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110668809 Nonpathogen - hypothetical protein HQ2913A 1 COG4634 COG4634, Uncharacterized protein conserved in bacteria Function unknown 110668373 Common - probable hydrolase HQ2457A 193 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110668961 Common tif5B translation initiation factor IF-2 HQ3074A 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 110668875 Common galE nucleoside-diphosphate-sugar epimerase (probable UDP-glucose 4-epimerase) HQ2986A 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110668062 Common - hypothetical protein HQ2117A 24 None None None 110667230 Common - predicted transporter HQ1261A 130 COG0679 COG0679, Predicted permeases General function prediction only 110667624 Common gckA probable hydroxypyruvate reductase; probable glycerate kinase HQ1667A 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 110669511 Common csg probable cell surface glycoprotein precursor HQ3661A 18 None None None 110669542 Common mtfK1 FKBP-type peptidylprolyl isomerase 1 HQ3692A 123 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 110667567 Nonpathogen - hypothetical protein HQ1608A 3 None None None 110668452 Common sfuC ABC-type spermidine/putrescine/iron transport system, ATP-binding protein HQ2543A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110668001 Nonpathogen - hypothetical protein HQ2056A 2 None None None 110669328 Nonpathogen - hypothetical protein HQ3458A 8 COG1645 COG1645, Uncharacterized Zn-finger containing protein General function prediction only 110667385 Common modA ABC-type transport system, substrate binding domain (probable substrates sulfate, thiosulfate or molybdate) HQ1423A 25 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 110668736 Nonpathogen rpl22p 50S ribosomal protein L22P HQ2837A 34 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 110667764 Common hsp20 hsp20-type chaperone HQ1810A 165 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110669094 Nonpathogen - hypothetical protein HQ3210A 1 None None None 110668927 Nonpathogen - hypothetical protein HQ3038A 1 None None None 110668043 Nonpathogen - probable integrase (PhiCh1 Int1-like) HQ2098A 1 None None None 110667483 Common acyP acylphosphatase HQ1523A 109 COG1254 AcyP, Acylphosphatases Energy production and conversion 110669151 Nonpathogen - hypothetical protein; probable calcium binding HQ3270A 1 None None None 110669353 Nonpathogen - hypothetical protein HQ3485A 3 None None None 110667842 Common kch Kef-type K+ transport systems, predicted NAD-binding component HQ1888A 86 None None None 110668230 Common - predicted atp-binding cobalamin adenosyltransferase HQ2299A 128 COG2096 COG2096, Uncharacterized conserved protein Function unknown 110668459 Common glcD probable oxidoreductase (probable glycolate oxidase iron-sulfur subunit) HQ2550A 205 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110669360 Nonpathogen - transcriptional regulator HQ3496A 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110669134 Nonpathogen - hypothetical protein HQ3253A 4 None None None 110668920 Common cbiX conserved cobalamin cluster protein CbiX (probable ferredoxin-like iron-sulfur protein) HQ3032A 100 COG2138 COG2138, Uncharacterized conserved protein Function unknown 110667004 Nonpathogen - IS1341-type transposase (nonfunctional,N-terminal part) HQ1027C 4 None None None 110669073 Common cobW cobalamin synthesis protein/P47K HQ3189A 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110668714 Nonpathogen - hypothetical protein HQ2815A 1 None None None 110669334 Common aslA probable arylsulfatase; probable choline-sulfatase HQ3464A 77 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110669547 Common ligA DNA ligase (NAD) HQ3698A 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 110667188 Nonpathogen - hypothetical protein HQ1218A 2 COG3462 COG3462, Predicted membrane protein Function unknown 110667701 Nonpathogen - hypothetical protein HQ1747A 3 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 110669282 Nonpathogen tfbA transcription initiation factor TFB HQ3408A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110668109 Nonpathogen - hypothetical protein HQ2170A 3 None None None 110667918 Common - ABC-type multidrug transport system, ATP-binding and permease protein HQ1969A 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110667542 Common - phospholipase D HQ1583A 39 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110668935 Nonpathogen - conserved coaE operon protein HQ3046A 20 COG1931 COG1931, Uncharacterized protein conserved in archaea Function unknown 110668494 Nonpathogen minD cell division inhibitor MinD-like (ATPase involved in chromosome partitioning) HQ2587A 12 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110667090 Common nirA ferredoxin--nitrite reductase HQ1116A 163 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 110668686 Common sppA Protease IV; endopeptidase IV; probable signal peptide peptidase HQ2787A 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110669348 Common - hypothetical protein HQ3480A 61 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 110667556 Nonpathogen - hypothetical protein HQ1597A 2 None None None 110667721 Common folCP folylpolyglutamate synthase / dihydropteroate synthase HQ1767A 230 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 110669510 Nonpathogen - hypothetical protein HQ3660A 3 None None None 110669305 Common htpX heat shock protein HtpX HQ3431A 195 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 110667431 Common pstC ABC-type phosphate transport system, permease protein II HQ1470A 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110668463 Nonpathogen - hypothetical protein HQ2554A 1 None None None 110668405 Common galE nucleoside-diphosphate-sugar epimerase (probable UDP-glucose 4-epimerase) HQ2494A 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110667665 Common sufB ABC-type transport system involved in Fe-S cluster assembly, permease protein II HQ1708A 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 110669190 Nonpathogen - hypothetical protein HQ3312A 4 None None None 110667423 Nonpathogen - succinylglutamate desuccinylase / aspartoacylase family protein HQ1462A 4 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 110668543 Common sun tRNA and rRNA cytosine-C5-methylases HQ2637A 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 110667181 Nonpathogen - hypothetical protein HQ1210A 1 None None None 110667288 Nonpathogen - hypothetical protein HQ1322A 4 None None None 110668748 Nonpathogen - translation initiation factor IF-2 subunit beta HQ2850A 34 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 110667067 Nonpathogen - hypothetical protein HQ1092A 1 None None None 110668183 Common cysU ABC-type sulfate/molybdate transport systems,permease protein HQ2246A 213 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110667801 Common proC pyrroline-5-carboxylate reductase HQ1846A 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 110667103 Common fdhAI NADH:ubiquinone oxidoreductase / formate dehydrogenase alpha subunit I HQ1129A 184 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110668273 Nonpathogen - hypothetical protein HQ2347A 7 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 110669219 Common moeA molybdenum cofactor biosynthesis protein MoeA; periplasmic molybdate-binding domain HQ3344A 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110667371 Nonpathogen cobY GTP:adenosylcobinamide-phosphate guanylyltransferase HQ1409A 20 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 110669008 Common trpD anthranilate phosphoribosyltransferase HQ3122A 211 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 110668150 Common nirA ferredoxin--nitrite reductase HQ2212A 165 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 110667864 Common - hypothetical protein HQ1912A 6 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 110669246 Common pho probable sugar phosphatase HQ3371A 117 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 110669341 Nonpathogen - hypothetical protein HQ3473A 9 None None None 110669117 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase HQ3235A 67 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 110667655 Nonpathogen - hypothetical protein HQ1698A 4 None None None 110667279 Nonpathogen - hypothetical protein HQ1312A 4 None None None 110669426 Nonpathogen - hypothetical protein HQ3568A 3 None None None 110668989 Nonpathogen - hypothetical protein HQ3103A 1 None None None 110668054 Nonpathogen - hypothetical protein HQ2109A 1 None None None 110669294 Nonpathogen pfdA prefoldin alpha subunit HQ3420A 16 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 110668364 Common oxr probable oxidoreductase HQ2448A 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 110668293 Common putP sodium/proline symporter HQ2370A 51 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 110667595 Common purE phosphoribosylaminoimidazole carboxylase catalytic chain HQ1636A 227 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 110668514 Common arsR arsenical resistance operon repressor (transcription regulator) HQ2607A 67 COG0640 ArsR, Predicted transcriptional regulators Transcription 110669148 Common - phage integrase homolog; halovirus HF1/2 protein HQ3267A 7 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110667192 Nonpathogen - hypothetical protein HQ1222A 4 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 110668508 Common phnI Phosphonate metabolism protein PhnI HQ2601A 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 110667479 Common - hypothetical protein HQ1518A 48 COG3332 COG3332, Uncharacterized conserved protein Function unknown 110668896 Nonpathogen - hypothetical protein HQ3008A 1 None None None 110667504 Common nthA endonuclease III; DNA-(apurinic or apyrimidinic site) lyase HQ1545A 236 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 110669533 Common tatC1 sec-independent protein translocase component TatC1 HQ3683A 199 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 110668482 Nonpathogen - hypothetical protein HQ2574A 9 COG1745 COG1745, Predicted metal-binding protein General function prediction only 110667470 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase HQ1509A 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 110667907 Common usp probable stress response protein HQ1957A 156 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110669269 Common rpoB1 DNA-directed RNA polymerase subunit B' HQ3395A 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 110669182 Common livM ABC-type branched-chain amino acid transport system, permease protein II HQ3302A 151 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110667110 Nonpathogen - hypothetical protein HQ1136A 20 COG2098 COG2098, Uncharacterized protein conserved in archaea Function unknown 110668827 Common rps2P 30S ribosomal protein S2 HQ2934A 110 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 110669485 Common - probable cationic amino acids transporter/stress response protein HQ3634A 150 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110667560 Common - probable S-adenosylmethionine-dependent methyltransferase HQ1601A 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110669258 Common rps10p 30S ribosomal protein S10P HQ3384A 147 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 110668814 Common agxT aminotransferase class V (Serine--pyruvate aminotransferase 2; Alanine--glyoxylate aminotransferase 2) HQ2919A 167 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 110667599 Common nuoH NADH dehydrogenase, subunit H (ubiquinone) HQ1640A 185 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 110668022 Common - site-specific DNA-methyltransferase HQ2077A 77 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 110667910 Common usp probable stress response protein HQ1960A 150 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110668658 Common livG ABC-type branched-chain amino acid transport systems, ATP-binding protein I HQ2757A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110668728 Common rpl5p 50S ribosomal protein L5P HQ2829A 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 110668997 Nonpathogen - hypothetical protein HQ3111A 4 None None None 110668224 Nonpathogen - hypothetical protein HQ2293A 1 None None None 110667235 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B HQ1266A 210 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 110668864 Nonpathogen - hypothetical protein HQ2973A 4 None None None 110668129 Nonpathogen - probable transcriptional regulator HQ2190A 2 None None None 110668073 Common - hypothetical protein HQ2130A 11 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110667300 Nonpathogen - conserved rpo operon protein HQ1336A 10 COG1412 COG1412, Uncharacterized proteins of PilT N-term./Vapc superfamily General function prediction only 110668769 Common - acetyltransferase HQ2871A 3 COG0456 RimI, Acetyltransferases General function prediction only 110668081 Nonpathogen - hypothetical protein HQ2138A 2 None None None 110669026 Common - hypothetical protein HQ3141A 55 COG1808 COG1808, Predicted membrane protein Function unknown 110667586 Common btuC corrinoid ABC transporter permease HQ1627A 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110669210 Common uppS di-trans,poly-cis-decaprenylcistransferase HQ3332A 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110668674 Common lrp transcription regulator HQ2773A 63 COG1522 Lrp, Transcriptional regulators Transcription 110667240 Nonpathogen kin predicted archaeal sugar kinase HQ1271A 31 COG1829 COG1829, Predicted archaeal kinase (sugar kinase superfamily) General function prediction only 110667824 Nonpathogen - hypothetical protein HQ1870A 9 COG1745 COG1745, Predicted metal-binding protein General function prediction only 110667208 Nonpathogen - hypothetical protein HQ1239A 3 None None None 110669141 Nonpathogen tfx hypothetical protein HQ3260A 17 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 110667339 Common - hydrolase (probable hydroxyacylglutathione hydrolase) HQ1377A 168 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110667495 Common korA oxoglutarate--ferredoxin oxidoreductase, alpha subunit HQ1536A 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 110667717 Common usp probable stress response protein HQ1763A 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667265 Common phr deoxyribodipyrimidine photolyase HQ1298A 132 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 110668100 Nonpathogen - hypothetical protein HQ2160A 1 None None None 110667126 Common - probable ABC-type transport system periplasmic substrate-binding protein (probable substrate iron(III)) HQ1152A 76 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110667334 Common - putative ATPase RIL HQ1372A 249 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 110668322 Common mcmA methylmalonyl-CoA mutase, subunit A HQ2400A 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 110668420 Common trxA thioredoxin HQ2511A 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110667323 Common gapB glyceraldehyde-3-phosphate dehydrogenase HQ1360A 38 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110668013 Common - hypothetical protein HQ2068A 8 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 110669156 Common - probable type II restriction/modification enzyme HQ3275A 57 None None None 110667117 Common nosY ABC-type copper transport system involved in multi-copper enzyme maturation, permease protein HQ1143A 35 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 110667615 Nonpathogen - hypothetical protein HQ1658A 2 None None None 110668948 Nonpathogen - hypothetical protein HQ3061A 16 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 110669314 Common - hypothetical protein HQ3442A 41 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110669456 Nonpathogen - chitinase TP rich domain homolog HQ3600A 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667390 Nonpathogen - hypothetical protein HQ1428A 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110668972 Nonpathogen gloA lactoylglutathione lyase HQ3086A 2 None None None 110669235 Common tpiA triosephosphate isomerase HQ3360A 40 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 110668429 Nonpathogen - hypothetical protein HQ2520A 1 None None None 110668523 Common - hypothetical protein HQ2617A 11 None None None 110667953 Common nolA NADH dehydrogenase 32K chain homolog HQ2004A 56 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110668329 Nonpathogen padR transcription regulator HQ2407A 4 COG1695 COG1695, Predicted transcriptional regulators Transcription 110669245 Common - transposase homolog (ISHnew96) HQ3370A 15 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 110669473 Nonpathogen cbiM2 ABC-type cobalt transport system, permease protein HQ3622A 6 None None None 110668204 Common - CBS domain membrane associated protein HQ2269A 214 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110668330 Nonpathogen - hypothetical protein HQ2408A 4 None None None 110669160 Nonpathogen - hypothetical protein HQ3279A 1 None None None 110667260 Nonpathogen - hypothetical protein HQ1293A 2 None None None 110667447 Common dppA ABC-type dipeptide/oligopeptide/nickel transport system, substrate binding protein HQ1486A 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110667782 Nonpathogen - hypothetical protein HQ1827A 1 None None None 110668780 Nonpathogen rpl24R ribosomal protein L24.eR HQ2883A 28 COG2075 RPL24A, Ribosomal protein L24E Translation, ribosomal structure and biogenesis 110669538 Nonpathogen priB probable DNA primase large subunit HQ3688A 22 COG2219 PRI2, Eukaryotic-type DNA primase, large subunit DNA replication, recombination, and repair 110667314 Nonpathogen pchB potassium channel protein homolog HQ1350A 18 COG3273 COG3273, Uncharacterized conserved protein Function unknown 110668615 Common tif2Ba translation initiation factor 2B alpha chain HQ2713A 58 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 110668576 Nonpathogen - hypothetical protein HQ2670A 3 None None None 110669060 Common - hypothetical protein HQ3176A 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 110668427 Nonpathogen - hypothetical protein HQ2518A 1 None None None 110667974 Common - probable ATP/GTP-binding protein HQ2027A 22 COG3410 COG3410, Uncharacterized conserved protein Function unknown 110669045 Common - hypothetical protein HQ3160A 42 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 110668661 Nonpathogen - hypothetical protein HQ2760A 4 None None None 110668476 Nonpathogen flpA fibrillarin HQ2567A 34 COG1889 NOP1, Fibrillarin-like rRNA methylase Translation, ribosomal structure and biogenesis 110668323 Common glo lyase / dioxygenase (probable lactoylglutathione lyase, aromatic compounds dioxygenase) HQ2401A 85 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 110669099 Common hmgR hydroxymethylglutaryl-CoA reductase (NADPH) HQ3215A 45 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 110667332 Nonpathogen - probable transcription regulator, arsR family HQ1370A 13 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 110667577 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ1618A 140 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110667493 Nonpathogen - predicted electron-transferring-flavoprotein dehydrogenase HQ1534A 34 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 110667440 Common dppC ABC-type dipeptide/oligopeptide/nickel transport system, permease components II HQ1479A 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110669535 Common ftsJ ribosomal RNA large subunit methyltransferase J HQ3685A 149 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 110668518 Common - conserved hypothetical protein / permease HQ2611A 69 COG0701 COG0701, Predicted permeases General function prediction only 110669315 Common hemB delta-aminolevulinic acid dehydratase HQ3443A 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 110668646 Nonpathogen - hypothetical protein HQ2745A 1 None None None 110669091 Common hit probable histidine triad (HIT) hydrolase (probable bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)) HQ3207A 99 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 110668571 Common purM phosphoribosylaminoimidazole synthetase HQ2665A 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 110669173 Nonpathogen - hypothetical protein HQ3292A 1 None None None 110668789 Nonpathogen rpl37e 50S ribosomal protein L37e HQ2892A 29 COG2126 RPL37A, Ribosomal protein L37E Translation, ribosomal structure and biogenesis 110667811 Common gcvT aminomethyltransferase, glycin cleavage system T protein HQ1856A 175 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 110669455 Nonpathogen - hypothetical protein HQ3599A 1 None None None 110667726 Nonpathogen gvpK gas-vesicle operon protein gvpK HQ1772A 2 None None None 110669252 Nonpathogen - IS1341-type transposase (nonfunctional, central part) HQ3378C 1 None None None 110667943 Common - hypothetical protein HQ1994A 12 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 110669470 Common urtA ABC-type urea transport systems,substrate-binding protein HQ3619A 126 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110668421 Nonpathogen - hypothetical protein HQ2512A 7 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 110667501 Common - probable substrate efflux/proton antiporter HQ1542A 88 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 110669067 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ3183A 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110668180 Common - hypothetical protein HQ2243A 7 None None None 110667328 Nonpathogen - hypothetical protein HQ1366A 3 None None None 110669247 Nonpathogen - hypothetical protein HQ3372A 2 None None None 110668019 Nonpathogen - hypothetical protein HQ2074A 1 None None None 110668299 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A HQ2376A 123 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 110668623 Common - hesB/IscA family protein HQ2721A 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 110668946 Common grx probable glutaredoxin HQ3059A 10 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110669512 Nonpathogen mcm ATP-dependent DNA helicase (intein-containing) HQ3662A 35 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 110669377 Nonpathogen - hypothetical protein HQ3515A 3 None None None 110669169 Nonpathogen - hypothetical protein HQ3288A 1 COG2898 COG2898, Uncharacterized conserved protein Function unknown 110669405 Common - hexosyltransferase; glycosyltransferase HQ3544A 232 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110668722 Nonpathogen rpl18p 50S ribosomal protein L18P HQ2823A 34 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 110667267 Common hisE phosphoribosyl-ATP pyrophosphatase HQ1300A 178 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 110668092 Nonpathogen - hypothetical protein HQ2151A 2 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 110669047 Common tif1 translation initiation factor Sui1 HQ3162A 46 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 110669107 Nonpathogen - hypothetical protein HQ3225A 1 None None None 110667790 Common cbiM cobalt transport protein CbiM HQ1835A 78 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 110667712 Common - Predicted deacylase HQ1758A 49 COG3608 COG3608, Predicted deacylase General function prediction only 110668534 Common gbp translation-associated GTPase HQ2628A 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 110667231 Common mtaP 5'-methylthioadenosine phosphorylase MtaP HQ1262A 163 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110669152 Nonpathogen int phage integrase HQ3271A 11 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110669306 Common - IS1341-type transposase (nonfunctional,N-terminal part) HQ3432A 66 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667403 Nonpathogen - hypothetical protein HQ1441A 1 None None None 110669251 Nonpathogen - hypothetical protein HQ3377A 1 None None None 110667555 Common - probable hemagglutinin like cellsurface protein HQ1596A 7 None None None 110668061 Nonpathogen - hypothetical protein HQ2116A 1 None None None 110669525 Common - probable nuclease HQ3675A 90 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 110669208 Common - hypothetical protein HQ3330A 44 COG1836 COG1836, Predicted membrane protein Function unknown 110669295 Nonpathogen rplX 50S ribosomal protein LX HQ3421A 5 COG2157 RPL20A, Ribosomal protein L20A (L18A) Translation, ribosomal structure and biogenesis 110668253 Common ligB DNA ligase (ATP) HQ2327A 96 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 110667148 Nonpathogen - hypothetical protein HQ1174A 4 None None None 110668513 Nonpathogen - hypothetical protein HQ2606A 19 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110668866 Common - hypothetical protein HQ2975A 18 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 110669529 Common rpiA ribose-5-phosphate epimerase HQ3679A 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 110667961 Nonpathogen - hypothetical protein HQ2013A 1 None None None 110667313 Common citZ citrate (si)-synthase HQ1349A 195 COG0372 GltA, Citrate synthase Energy production and conversion 110667463 Nonpathogen - hypothetical protein HQ1502A 1 None None None 110668993 Nonpathogen nifUx nifU protein C-terminal domain homolog HQ3107A 4 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 110668023 Common - site-specific DNA-methyltransferase HQ2078A 102 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 110669143 Nonpathogen - hypothetical protein HQ3262A 3 None None None 110669507 Nonpathogen - hypothetical protein HQ3657A 2 None None None 110669019 Nonpathogen - hypothetical protein HQ3134A 4 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 110667917 Common - predicted dehydrogenase HQ1968A 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 110668351 Common - deoxyribodipyrimidine photolyase-related protein HQ2431A 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 110667797 Common folA dihydrofolate reductase HQ1842A 144 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 110668812 Nonpathogen - hypothetical protein HQ2916A 2 None None None 110669532 Common trmU tRNA methyl transferase HQ3682A 84 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 110668971 Common - hypothetical protein HQ3085A 11 None None None 110667318 Common thrC threonine synthase HQ1355A 103 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 110668976 Nonpathogen - hypothetical protein HQ3090A 5 None None None 110669506 Common minD cell division inhibitor MinD-like (ATPase involved in chromosome partitioning) HQ3656A 40 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110668504 Common phnC ABC-type phosphate/phosphonate transport system,ATPase protein HQ2597A 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 110668085 Nonpathogen - hypothetical protein HQ2143A 1 None None None 110668541 Common - hypothetical protein HQ2635A 23 COG3372 COG3372, Uncharacterized conserved protein Function unknown 110667978 Common amyA alpha amylase HQ2031A 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110668708 Common livJ ABC-type branched-chain amino acid transport systems, substrate-binding protein HQ2809A 143 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110667448 Common oxlT probable oxalate/formate antiporter HQ1487A 81 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110669024 Nonpathogen - hypothetical protein HQ3139A 25 COG2042 COG2042, Uncharacterized conserved protein Function unknown 110668684 Nonpathogen - hypothetical protein HQ2784A 1 None None None 110669545 Common nosF ABC-type copper transport system, ATP-binding protein HQ3696A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110667949 Common - hypothetical protein HQ2000A 36 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 110668245 Common maoC maoC protein homolog; probable enoyl-CoA hydratase HQ2315A 67 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110668466 Common trxA thioredoxin HQ2557A 5 None None None 110668598 Nonpathogen - hypothetical protein HQ2695A 4 None None None 110668987 Common pgi glucose-6-phosphate isomerase HQ3101A 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 110667262 Common - ABC-type transport system, ATP-binding protein HQ1295A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110667587 Common hemT ABC-type cobalamin/Iron(III)-siderophore transport systems, substrate-binding protein HQ1628A 113 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110668545 Common grpE dnaJ/dnaK ATPase stimulator grpE HQ2639A 223 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 110669342 Common moxR MoxR-like ATPase (methanol dehydrogenase regulatory protein) HQ3474A 180 COG0714 COG0714, MoxR-like ATPases General function prediction only 110667747 Common thiJ probable chaperone HQ1793A 80 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 110668656 Common livH ABC-type branched-chain amino acid transport system, permease protein I HQ2755A 159 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110667108 Nonpathogen - hypothetical protein HQ1134A 3 None None None 110669159 Nonpathogen - hypothetical protein HQ3278A 2 None None None 110667980 Common xseAl exodeoxyribonuclease VII large subunit HQ2033A 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 110667862 Common - probable signal-transducing histidine kinase; PAS/PAC domain protein HQ1910A 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110667308 Nonpathogen - hypothetical protein HQ1344A 4 COG4748 COG4748, Uncharacterized conserved protein Function unknown 110667291 Nonpathogen - hypothetical protein HQ1326A 1 None None None 110668099 Nonpathogen - hypothetical protein HQ2159A 4 None None None 110669361 Nonpathogen - hypothetical protein HQ3497A 7 COG2402 COG2402, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110667097 Common glo lyase/ dioxygenase (probable lactoylglutathione lyase, aromatic compounds dioxygenase) HQ1123A 21 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110666989 Nonpathogen - hypothetical protein HQ1013A 1 None None None 110668279 Common fdfT farnesyl-diphosphate farnesyltransferase (squalene synthase) HQ2353A 52 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 110668856 Common livM ABC-type branched-chain amino acid transport system, permease protein II HQ2963A 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110668371 Common folA dihydrofolate reductase HQ2455A 140 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 110668389 Common dppB ABC-type dipeptide/oligopeptide/nickel transport systems, permease protein HQ2476A 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110667662 Common polB1 DNA-directed DNA polymerase (family B) HQ1705A 59 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 110667372 Nonpathogen cobS cobalamin (5'-phosphate) synthase HQ1410A 6 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 110669268 Common rpoA DNA-directed RNA polymerase subunit alpha HQ3394A 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 110668326 Nonpathogen - hypothetical protein HQ2404A 15 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 110667956 Common moaA molybdopterin-based tungsten cofactor biosynthesis protein HQ2007A 199 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 110669410 Common - hexosyltransferase; glycosyltransferase HQ3549A 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667000 Common pmm phosphohexomutase (phosphoglucomutase; phosphomannomutase) HQ1024A 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110669350 Nonpathogen - hypothetical protein HQ3482A 2 None None None 110667258 Nonpathogen - hypothetical protein HQ1291A 6 COG1430 COG1430, Uncharacterized conserved protein Function unknown 110669236 Nonpathogen - transcriptional regulator HQ3361A 27 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 110669261 Nonpathogen - predicted allosteric regulator of homoserine dehydrogenase HQ3387A 18 COG2061 COG2061, ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase Amino acid transport and metabolism 110667070 Common - probable metalloprotease/metallo peptidase HQ1095A 47 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 110668886 Nonpathogen - hypothetical protein HQ2998A 3 None None None 110667285 Nonpathogen - IS1341-type transposase (nonfunctional,C-terminal part) HQ1317B 3 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668049 Nonpathogen - hypothetical protein HQ2104A 1 None None None 110669112 Nonpathogen cdsA hypothetical protein HQ3230A 28 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 110667601 Nonpathogen nuoJ NADH dehydrogenase subunit J HQ1643A 4 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 110668433 Common - hypothetical protein HQ2524A 60 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110669425 Nonpathogen - hypothetical protein HQ3567A 2 None None None 110667656 Common alkK acyl-CoA synthetase II; probable long-chain-fatty-acid--CoA ligase HQ1699A 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110668522 Nonpathogen - hypothetical protein HQ2615A 3 None None None 110667006 Common upp uracil phosphoribosyltransferase HQ1029A 163 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 110668490 Nonpathogen - hypothetical protein HQ2583A 5 None None None 110667183 Nonpathogen - hypothetical protein HQ1212A 3 None None None 110667109 Common - sugar epimerase/dehydratase homolog HQ1135A 102 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110667477 Common psmA1 proteasome subunit alpha HQ1516A 40 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 110667134 Nonpathogen ogt methylated-DNA--protein-cysteine methyltransferase HQ1160A 9 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 110668042 Nonpathogen - hypothetical protein HQ2097A 3 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 110668205 Common nagD putative N-acetyl-glucosamine catabolism protein HQ2270A 109 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 110668311 Nonpathogen - hypothetical protein HQ2388A 3 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 110667927 Common - NCAIR mutase (PurE)-related protein HQ1978A 65 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 110666982 Nonpathogen purH IMP cyclohydrolase HQ1006A 13 COG3363 COG3363, Archaeal IMP cyclohydrolase Nucleotide transport and metabolism 110668059 Nonpathogen - pentapeptide repeats family protein HQ2114A 2 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110668669 Nonpathogen - hypothetical protein HQ2768A 2 None None None 110667387 Common moeB molybdenum cofactor biosynthesis protein MoeB HQ1425A 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 110668966 Nonpathogen - azlC associated membrane protein homolog HQ3079A 4 COG4392 COG4392, Predicted membrane protein Function unknown 110667482 Common pmm3 phosphohexomutase 3 (phosphoglucomutase); phosphomannomutase) HQ1522A 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110668603 Nonpathogen - hypothetical protein HQ2701A 1 None None None 110667226 Nonpathogen - hypothetical protein HQ1257A 25 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 110668806 Nonpathogen fixC electron-transferring-flavoprotein dehydrogenase HQ2910A 14 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 110667766 Common aspC PLP-dependent aminotransferase (probable aspartate aminotransferase ) HQ1812A 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110668237 Nonpathogen cbiM ABC-type cobalt transport system, permease protein I HQ2306A 2 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 110668343 Common - hypothetical protein HQ2421A 6 None None None 110668925 Common asnA asparaginase HQ3036A 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 110668499 Nonpathogen - hypothetical protein HQ2592A 4 None None None 110667902 Common kch Kef-type potassium transport systems, predicted NAD-binding protein HQ1952A 163 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110667836 Nonpathogen - hypothetical protein HQ1882A 4 None None None 110667009 Nonpathogen - hypothetical protein HQ1032A 2 None None None 110668531 Common - glycosyltransferase homolog HQ2625A 132 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110667706 Common smc chromosome partition protein HQ1752A 20 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 110667020 Common serA phosphoglycerate dehydrogenase HQ1043A 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110669480 Common ureD urease accessory protein HQ3629A 51 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 110667283 Common - IS200-type transposase HQ1316A 49 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667806 Common - predicted helicase HQ1851A 161 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 110668900 Common - hypothetical protein HQ3012A 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 110669383 Nonpathogen - probable transposase (ISH5) (fragment) HQ3521A 2 None None None 110667629 Common apt adenine phosphoribosyltransferase HQ1672A 130 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110668801 Nonpathogen - hypothetical protein HQ2904A 1 None None None 110667867 Nonpathogen - hypothetical protein HQ1915A 6 COG4344 COG4344, Uncharacterized protein conserved in archaea Function unknown 110669332 Nonpathogen - hypothetical protein HQ3462A 1 None None None 110667393 Common potA ABC-type spermidine/putrescine transport systems, ATPase domain HQ1431A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110667986 Nonpathogen - hypothetical protein HQ2039A 1 None None None 110668676 Nonpathogen - protein N-acetyltransferase HQ2775A 7 COG3393 COG3393, Predicted acetyltransferase General function prediction only 110668149 Common narB nitrate reductase, catalytic subunit HQ2211A 183 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110669102 Common pyrF orotidine-5'-phosphate decarboxylase HQ3219A 82 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 110668968 Nonpathogen - hypothetical protein HQ3082A 1 None None None 110667704 Common moxR MoxR-like ATPase HQ1750A 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 110667891 Common xdhC xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family HQ1941A 104 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 110668546 Common dnaK dnaK-type molecular chaperone hsp70 HQ2640A 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 110667099 Common cat2 cationic amino acid transport protein HQ1125A 179 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 110668556 Common galE nucleoside-diphosphate-sugar epimerase (probable UDP-glucose 4-epimerase) HQ2650A 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110669086 Common gfoR glucose--fructose oxidoreductase HQ3202A 133 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110669447 Nonpathogen - hypothetical protein HQ3591A 1 None None None 110667568 Nonpathogen - conserved cox cluster protein HQ1609A 2 None None None 110668741 Common rpl3p 50S ribosomal protein L3P HQ2842A 97 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 110667877 Nonpathogen - hypothetical protein HQ1926A 5 None None None 110667229 Common prt predicted phosphoribosyltransferase HQ1260A 43 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 110667359 Common - hypothetical protein HQ1397A 18 COG2339 COG2339, Predicted membrane protein Function unknown 110667962 Common ywaD probable peptidase HQ2014A 45 COG2234 Iap, Predicted aminopeptidases General function prediction only 110669004 Common rimI protein N-acetyltransferase HQ3118A 180 COG0456 RimI, Acetyltransferases General function prediction only 110669275 Nonpathogen - hypothetical protein HQ3401A 1 None None None 110668974 Common - hypothetical protein HQ3088A 14 COG4357 COG4357, Uncharacterized conserved protein Function unknown 110668478 Nonpathogen - hypothetical protein HQ2569A 3 None None None 110669058 Common radB DNA repair and recombination protein RadB HQ3173A 143 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 110667810 Common degP serine proteinase HQ1855A 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110668660 Nonpathogen - probable C2H2 zinc finger DNA-binding protein HQ2759A 2 None None None 110667676 Nonpathogen - hypothetical protein HQ1719A 4 None None None 110667780 Nonpathogen - hypothetical protein HQ1825A 2 None None None 110667022 Nonpathogen topA DNA topoisomerase I HQ1045A 11 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 110668175 Common ocd ornithine cyclodeaminase HQ2237A 89 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110668140 Common - PemK-like growth inhibitor protein (MazF protein) HQ2202A 52 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 110668345 Common ptpS 6-pyruvoyltetrahydropterin synthase (4.2.3.12) HQ2423A 21 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 110667670 Common - IS1341-type transposase HQ1713A 26 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667224 Common tif2a translation initiation factor IF-2 subunit alpha HQ1255A 125 COG1093 SUI2, Translation initiation factor 2, alpha subunit (eIF-2alpha) Translation, ribosomal structure and biogenesis 110668839 Nonpathogen - hypothetical protein HQ2946A 1 None None None 110668178 Common hyuB N-methylhydantoinase B (ATP-hydrolyzing) HQ2241A 95 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110667537 Common coxB cytochrome-c-like terminal oxidase, subunit II HQ1578A 161 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 110667151 Nonpathogen hsp20 hsp20 type chaperone HQ1177A 7 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110667983 Common elaC Ribonuclease Z (RNase Z) (tRNA 3 endonuclease) HQ2036A 134 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 110667852 Nonpathogen - hypothetical protein HQ1900A 4 COG1378 COG1378, Predicted transcriptional regulators Transcription 110668952 Common - superfamily II helicase HQ3065A 153 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 110669041 Nonpathogen - hypothetical protein HQ3156A 1 None None None 110667245 Common dcd deoxycytidine triphosphate deaminase HQ1278A 170 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 110668528 Common - hypothetical protein HQ2622A 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 110668222 Nonpathogen - hypothetical protein HQ2290A 1 COG3313 COG3313, Predicted Fe-S protein General function prediction only 110669110 Common apt adenine phosphoribosyltransferase HQ3228A 25 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110668813 Common - hypothetical protein HQ2917A 7 COG4190 COG4190, Predicted transcriptional regulator Transcription 110668128 Common sdt sodium-dependent transporter (probable antiporter) HQ2189A 83 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 110668857 Common livG ABC-type branched-chain amino acid transport systems, ATP-binding protein I HQ2964A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110668825 Nonpathogen - hypothetical protein HQ2932A 1 None None None 110668336 Common fer ferredoxin HQ2414A 76 COG0633 Fdx, Ferredoxin Energy production and conversion 110667677 Common citE citryl-CoA lyase HQ1720A 35 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 110667685 Nonpathogen pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase (Phosphatidylglycerophosphate synthase) (PGP synthase) HQ1730A 5 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110668300 Nonpathogen - hypothetical protein HQ2377A 1 None None None 110669565 Common argB acetylglutamate kinase HQ3716A 193 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 110669130 Common atpI H(+)-transporting two-sector ATPase, subunit I (A-type ATP synthase) HQ3249A 36 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 110668820 Common - amino acid kinase HQ2926A 37 COG1608 COG1608, Predicted archaeal kinase General function prediction only 110667684 Common adh probable alcohol dehydrogenase (NADP+) HQ1729A 163 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 110668484 Common ogg DNA N-glycosylase / DNA lyase HQ2577A 21 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 110668121 Nonpathogen - hypothetical protein HQ2182A 1 None None None 110667088 Nonpathogen - hypothetical protein HQ1113A 1 None None None 110669121 Common argS arginine--tRNA ligase HQ3239A 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110668082 Nonpathogen - hypothetical protein HQ2140A 8 COG3370 COG3370, Uncharacterized protein conserved in archaea Function unknown 110667532 Common pykA pyruvate kinase HQ1573A 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110668446 Nonpathogen ferA_5 probable ferredoxin HQ2537A 3 COG0633 Fdx, Ferredoxin Energy production and conversion 110667436 Nonpathogen - hypothetical protein HQ1475A 3 None None None 110668848 Nonpathogen - cell division control protein cdc6 homolog HQ2955A 4 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110667558 Nonpathogen - hypothetical protein HQ1599A 4 None None None 110669483 Nonpathogen - probable insertion element protein (ISH2) HQ3632A 1 None None None 110669266 Common nusA transcription elongation factor NusA-like protein HQ3392A 87 COG0195 NusA, Transcription elongation factor Transcription 110669185 Common phoU ABC transport system regulatory protein HQ3307A 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110668398 Nonpathogen - hypothetical protein HQ2486A 1 None None None 110668448 Common sga1 glucoamylase HQ2539A 25 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 110668102 Nonpathogen - hypothetical protein HQ2162A 2 None None None 110667728 Nonpathogen gvpI gas-vesicle operon protein gvpI HQ1774A 2 None None None 110667465 Nonpathogen gar1 H/ACA RNA-protein complex component Gar1 HQ1504A 6 COG3277 GAR1, RNA-binding protein involved in rRNA processing Translation, ribosomal structure and biogenesis 110667077 Common thiL thiamin-phosphate kinase HQ1102A 186 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 110668365 Nonpathogen - hypothetical protein HQ2449A 1 None None None 110668063 Common ugpQ glycerophosphodiester phosphodiesterase HQ2118A 58 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110669217 Common phhB pterin-4-alpha-carbinolamine dehydratase HQ3342A 116 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 110667013 Common cstA carbon starvation protein A HQ1036A 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 110668004 Nonpathogen - hypothetical protein HQ2059A 2 None None None 110668303 Common - probable short chanin dehydrogenase/ reductase HQ2380A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110669126 Nonpathogen atpF V-type ATP synthase subunit F HQ3245A 14 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 110669554 Common - CBS domain protein HQ3705A 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110668930 Nonpathogen - hypothetical protein HQ3041A 1 None None None 110667640 Common dfp phosphopantothenoylcysteine decarboxylase/ phosphopantothenate--cysteine ligase HQ1683A 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 110667346 Common hisH imidazole glycerol phosphate synthase subunit HisH HQ1384A 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 110669585 Nonpathogen - hypothetical protein HQ3737A 14 COG3365 COG3365, Uncharacterized protein conserved in archaea Function unknown 110667166 Nonpathogen - probable cell surface glycoprotein HQ1193A 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 110668849 Nonpathogen - hypothetical protein HQ2956A 4 None None None 110667350 Common csp probable cold shock protein HQ1388A 163 COG1278 CspC, Cold shock proteins Transcription 110667990 Nonpathogen - probable phosphoesterase HQ2045A 3 COG1409 Icc, Predicted phosphohydrolases General function prediction only 110667734 Common gvpN gas-vesicle operon protein gvpN HQ1780A 77 COG0714 COG0714, MoxR-like ATPases General function prediction only 110668387 Nonpathogen - hypothetical protein HQ2474A 3 None None None 110667580 Nonpathogen - hypothetical protein HQ1621A 7 None None None 110669469 Common urtB ABC-type urea transport system, permease protein I HQ3618A 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110667622 Common - glutaredoxin homolog HQ1665A 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 110667761 Nonpathogen - hypothetical protein HQ1807A 4 None None None 110667570 Common coxA cytochrome-c-like terminal oxidase, subunit I HQ1611A 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 110668185 Common - hypothetical protein HQ2249A 17 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 110667363 Nonpathogen - hypothetical protein HQ1401A 1 None None None 110667831 Nonpathogen - hypothetical protein HQ1877A 4 None None None 110668163 Common - probable transcription regulator HQ2225A 143 COG1733 COG1733, Predicted transcriptional regulators Transcription 110668033 Nonpathogen - hypothetical protein HQ2088A 1 None None None 110668795 Nonpathogen ef1B elongation factor 1-beta HQ2898A 31 COG2092 EFB1, Translation elongation factor EF-1beta Translation, ribosomal structure and biogenesis 110668746 Common idiB isopentenyl-diphosphate delta-isomerase HQ2847A 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 110669356 Nonpathogen - hypothetical protein HQ3488A 1 None None None 110668586 Common ugd UDP-glucose 6-dehydrogenase HQ2680A 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 110669178 Nonpathogen - hypothetical protein HQ3298A 2 None None None 110669366 Common - glycosyltransferase (probable dolichyl-P-glucose synthetase) HQ3503A 132 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110667081 Nonpathogen - hypothetical protein HQ1106A 19 COG2117 COG2117, Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 110668139 Common - hypothetical protein HQ2201A 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 110668306 Nonpathogen - hypothetical protein HQ2383A 1 None None None 110667401 Nonpathogen - probable membrane-bound metal-dependent hydrolase HQ1439A 2 None None None 110667014 Nonpathogen - hypothetical protein HQ1037A 3 None None None 110667871 Nonpathogen - hypothetical protein HQ1920A 2 None None None 110668198 Common - hypothetical protein HQ2262A 5 None None None 110667590 Common mer3 ATP-dependent DNA helicase HQ1631A 152 COG1204 COG1204, Superfamily II helicase General function prediction only 110668213 Common entB Isochorismatase HQ2280A 105 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110667428 Common narK nitrate/nitrite transporter HQ1467A 189 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110667161 Nonpathogen - hypothetical protein HQ1188A 3 None None None 110667453 Common - stomatin homolog HQ1492A 222 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110668458 Common - IS1341-type transposase HQ2549A 63 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110669325 Common metY O-acetylhomoserine aminocarboxypropyltransferase; methionine synthase HQ3454A 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 110668378 Common - hypothetical protein HQ2462A 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 110668697 Common mch N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase HQ2798A 27 COG3252 COG3252, Methenyltetrahydromethanopterin cyclohydrolase Coenzyme metabolism 110668413 Common mscS probable mechanosensitive channel HQ2503A 194 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110668210 Nonpathogen - hypothetical protein HQ2277A 1 None None None 110668682 Nonpathogen - hypothetical protein HQ2782A 4 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110667813 Common - IS1341-type transposase HQ1859A 42 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667361 Common act acyl-CoA thioester hydrolase HQ1399A 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 110669038 Common cofE F420-0--gamma-glutamyl ligase HQ3153A 44 COG1478 COG1478, Uncharacterized conserved protein Function unknown 110667044 Nonpathogen - hypothetical protein HQ1068A 4 None None None 110668991 Common phnP PhnP-like protein HQ3105A 30 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 110669017 Common purQ phosphoribosylformylglycinamidine synthase component I HQ3131A 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 110667710 Common metF 5,10-methylenetetrahydrofolate reductase HQ1756A 72 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 110668633 Common glnP ABC-type glutamine/glutamate/polar amino acids transport system, permease protein HQ2731A 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110667414 Nonpathogen - hypothetical protein HQ1453A 3 None None None 110669461 Common - hypothetical protein HQ3605A 223 COG5340 COG5340, Predicted transcriptional regulator Transcription 110667340 Nonpathogen - hypothetical protein HQ1378A 4 None None None 110668251 Common - probable oxidoreductase, oxygen dependent,FAD-dependent protein HQ2325A 66 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110667421 Common mutS1 DNA mismatch repair protein HQ1460A 203 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110666999 Nonpathogen - hypothetical protein HQ1023A 4 None None None 110668261 Common - Nucleoside diphosphate sugar epimerase HQ2335A 141 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110669391 Nonpathogen - probable sulfatase HQ3529A 4 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110668614 Nonpathogen - hypothetical protein HQ2712A 2 None None None 110668761 Common crtI phytoene dehydrogenase (phytoene desaturase) HQ2863A 87 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110667841 Common - hypothetical protein HQ1887A 17 COG3388 COG3388, Uncharacterized protein conserved in archaea Function unknown 110667755 Common - hypothetical protein HQ1801A 62 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 110668767 Nonpathogen - probable transcriptional regulator HQ2869A 29 COG1709 COG1709, Predicted transcriptional regulator Transcription 110669284 Nonpathogen tbpE transcription factor HQ3410A 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 110667579 Common - protein N-acetyltransferase homolog HQ1620A 38 COG0456 RimI, Acetyltransferases General function prediction only 110667196 Nonpathogen - hypothetical protein HQ1226A 32 COG1602 COG1602, Uncharacterized conserved protein Function unknown 110668932 Nonpathogen - hypothetical protein HQ3043A 4 COG4742 COG4742, Predicted transcriptional regulator Transcription 110669339 Nonpathogen - probable cell surface glycoprotein HQ3469A 2 None None None 110669514 Common bioY biotin synthesis protein HQ3664A 108 COG1268 BioY, Uncharacterized conserved protein General function prediction only 110668391 Common dppDF ABC-type dipeptide/oligopeptide/nickel transport systems, ATP-binding protein I & II HQ2478A 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110668636 Nonpathogen - probable metallopeptidase HQ2735A 8 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110669568 Common argF ornithine carbamoyltransferase HQ3719A 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 110668511 Common phnL Phosphonates transport ATP-binding protein PhnL HQ2604A 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 110669033 Nonpathogen - hypothetical protein HQ3148A 4 None None None 110667603 Common nuoK NADH dehydrogenase, subunit K (ubiquinone) HQ1645A 159 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 110669437 Nonpathogen - hypothetical protein HQ3580A 1 None None None 110668189 Nonpathogen - hypothetical protein HQ2253A 3 None None None 110668229 Common cbiE cobalt-precorrin-6Y C(5)-methyltransferase HQ2298A 68 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 110668203 Nonpathogen - hypothetical protein HQ2268A 1 None None None 110669145 Nonpathogen - hypothetical protein HQ3264A 15 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 110669029 Nonpathogen - hypothetical protein HQ3144A 2 None None None 110669500 Common prsA ribose-phosphate pyrophosphokinase HQ3650A 242 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110668819 Common mvk mevalonate kinase HQ2925A 39 COG1577 ERG12, Mevalonate kinase Lipid metabolism 110669297 Nonpathogen rpl31R 50S ribosomal protein L31e HQ3423A 29 COG2097 RPL31A, Ribosomal protein L31E Translation, ribosomal structure and biogenesis 110668123 Common dctM TRAP-type C4-dicarboxylate transport system,large permease component DctM (YiaN) HQ2184A 131 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110668423 Nonpathogen - hypothetical protein HQ2514A 1 None None None 110669352 Common - IS1341-type transposase HQ3484A 62 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667638 Common phaA putative monovalent cation/H+ antiporter subunit D HQ1681A 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 110668950 Common lrp transcription regulator HQ3063A 78 COG1522 Lrp, Transcriptional regulators Transcription 110668986 Nonpathogen - hypothetical protein HQ3100A 3 None None None 110669220 Common moeA molybdenum cofactor biosynthesis protein MoeA HQ3345A 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110667915 Common rtcB RtcB-like protein HQ1965A 89 COG1690 RtcB, Uncharacterized conserved protein Function unknown 110667480 Nonpathogen - hypothetical protein HQ1519A 16 COG3388 COG3388, Uncharacterized protein conserved in archaea Function unknown 110668891 Common prkA predicted serine protein kinase HQ3003A 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 110667821 Nonpathogen tfbA transcription initiation factor TFB HQ1867A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667395 Common potC ABC-type spermidine/putrescine transport system,permease domain II HQ1433A 198 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110669523 Common pmm phosphohexomutase (phosphoglucomutase; phosphomannomutase) HQ3673A 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110667316 Common - hypothetical protein HQ1352A 51 COG3608 COG3608, Predicted deacylase General function prediction only 110668878 Common glmS glutamine--fructose-6-phosphate transaminase (isomerizing) HQ2990A 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 110667311 Nonpathogen - hypothetical protein HQ1347A 1 None None None 110667419 Nonpathogen - hypothetical protein HQ1458A 1 None None None 110669527 Nonpathogen - hypothetical protein HQ3677A 2 None None None 110668868 Nonpathogen - hypothetical protein HQ2977A 1 None None None 110669479 Common ureG urease accessory protein HQ3628A 153 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 110668258 Common - probable S-adenosylmethionine-dependent methyltransferase HQ2332A 50 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110669206 Common dnaG DNA primase HQ3328A 41 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 110669115 Common - IS1341-type transposase HQ3233A 20 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668486 Common thrS threonine--tRNA ligase HQ2579A 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667206 Common aspC PLP-dependent aminotransferase (probable aspartate aminotransferase) HQ1237A 234 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110669022 Common - hydrolase (probable hydroxyacylglutathione hydrolase) HQ3137A 76 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110668353 Nonpathogen - transcription regulator HQ2434A 10 COG3355 COG3355, Predicted transcriptional regulator Transcription 110668810 Common - hypothetical protein HQ2914A 12 COG2442 COG2442, Uncharacterized conserved protein Function unknown 110667305 Common gcp O-sialoglycoprotein endopeptidase/protein kinase HQ1341A 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 110667645 Common aatC aspartyl-tRNA(Asn) amidotransferase subunit C HQ1688A 103 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 110667508 Nonpathogen - hypothetical protein HQ1549A 3 None None None 110667745 Nonpathogen - hypothetical protein HQ1791A 2 None None None 110668662 Nonpathogen - hypothetical protein HQ2761A 1 None None None 110667330 Common argE acetylornithine deacetylase HQ1368A 183 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110667491 Nonpathogen - hypothetical protein HQ1531A 22 COG2237 COG2237, Predicted membrane protein Function unknown 110667295 Nonpathogen - hypothetical protein HQ1330A 3 None None None 110667489 Nonpathogen - hypothetical protein HQ1529A 25 COG2090 COG2090, Uncharacterized protein conserved in archaea Function unknown 110668290 Common adh alcohol dehydrogenase HQ2366A 198 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 110668182 Common cysT ABC-type sulfate/molybdate transport system,permease protein HQ2245A 190 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110669403 Nonpathogen - hypothetical protein HQ3542A 1 None None None 110667442 Common dppA ABC-type dipeptide/oligopeptide/nickel transport systems, substrate-binding protein HQ1481A 148 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110667620 Common gdh Glucose 1-dehydrogenase HQ1663A 102 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110667408 Nonpathogen - hypothetical protein HQ1446A 1 None None None 110667326 Nonpathogen pepQ aminopeptidase; probable Xaa-Pro aminopeptidase HQ1363A 15 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110667264 Nonpathogen - hypothetical protein HQ1297A 1 None None None 110669240 Common - oxidoreductase homolog HQ3365A 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 110668155 Nonpathogen - hypothetical protein HQ2217A 3 None None None 110668644 Nonpathogen - ribosomal protein S10 homolog HQ2743A 7 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 110667337 Nonpathogen - hypothetical protein HQ1375A 5 COG1255 COG1255, Uncharacterized protein conserved in archaea Function unknown 110667848 Nonpathogen - hypothetical protein HQ1895A 1 None None None 110667475 Common - S-adenosylmethionine-dependent methyltransferase homolog HQ1514A 30 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110667920 Nonpathogen - hypothetical protein HQ1971A 3 None None None 110669055 Common arsC probable arsenate reductase (glutaredoxin); probable protein-tyrosine-phosphatase HQ3170A 59 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110669229 Common lrp transcription regulator HQ3354A 143 COG1522 Lrp, Transcriptional regulators Transcription 110667809 Nonpathogen - hypothetical protein HQ1854A 5 COG2262 HflX, GTPases General function prediction only 110667061 Common lpdA dihydrolipoamide dehydrogenase HQ1085A 233 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110667582 Nonpathogen - hypothetical protein HQ1623A 2 None None None 110668944 Nonpathogen - hypothetical protein HQ3056A 33 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 110667153 Nonpathogen - hypothetical protein HQ1179A 4 None None None 110669238 Nonpathogen - predicted nucleotide kinase HQ3363A 26 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 110669196 Nonpathogen - hypothetical protein HQ3318A 4 None None None 110669061 Common aaa AAA-type ATPase (transitional ATPase homolog) HQ3177A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110668017 Common - IS1341-type transposase HQ2072A 43 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668313 Nonpathogen - transport protein (probable polysaccharide biosynthesis transport protein) HQ2390A 3 None None None 110668095 Common - IS1341-type transposase HQ2154A 76 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667321 Nonpathogen - hypothetical protein HQ1358A 19 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 110669097 Nonpathogen - hypothetical protein HQ3213A 11 COG3875 COG3875, Uncharacterized conserved protein Function unknown 110667052 Common fer ferredoxin (2Fe-2S) HQ1076A 45 COG0633 Fdx, Ferredoxin Energy production and conversion 110668724 Nonpathogen rpl32R 50S ribosomal protein L32e HQ2825A 34 COG1717 RPL32, Ribosomal protein L32E Translation, ribosomal structure and biogenesis 110668403 Nonpathogen - tRNA 2'-O-methylase HQ2492A 31 COG1303 COG1303, Uncharacterized protein conserved in archaea Function unknown 110667929 Common - hypothetical protein HQ1980A 47 COG3268 COG3268, Uncharacterized conserved protein Function unknown 110669201 Common pyroA pyridoxine biosynthesis protein HQ3323A 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 110668075 Nonpathogen - hypothetical protein HQ2132A 3 None None None 110667844 Nonpathogen - hypothetical protein HQ1890A 2 None None None 110669497 Nonpathogen - hypothetical protein HQ3647A 8 COG5431 COG5431, Uncharacterized metal-binding protein Function unknown 110668435 Nonpathogen - hypothetical protein HQ2526A 1 None None None 110667216 Common ilvE branched-chain amino acid aminotransferase HQ1247A 203 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110669419 Nonpathogen - probable transposase (ISH11) HQ3558A 3 None None None 110667592 Common ribE riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase) HQ1633A 28 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 110667784 Common cbiA cobyrinic acid a,c-diamide synthase HQ1829A 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 110666984 Common mer3 ski2-like helicase HQ1008A 128 COG1204 COG1204, Superfamily II helicase General function prediction only 110667708 Nonpathogen - hypothetical protein HQ1754A 10 None None None 110668583 Nonpathogen - hypothetical protein HQ2677A 4 None None None 110668923 Common cbiH1 precorrin-3B C17-methyltransferase 1 HQ3034A 146 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 110667002 Common hisB imidazoleglycerol-phosphate dehydratase HQ1026A 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 110667651 Nonpathogen - hypothetical protein HQ1694A 1 None None None 110667879 Common msrA peptide methionine sulfoxide reductase (S-form specific) HQ1929A 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110668904 Nonpathogen rps17E 30S ribosomal protein S17e HQ3016A 31 COG1383 RPS17A, Ribosomal protein S17E Translation, ribosomal structure and biogenesis 110668169 Common - major facilitator superfamily transporter HQ2231A 9 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110667526 Common - metallophosphoesterase HQ1567A 63 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 110668964 Common - IS1341-type transposase HQ3077A 59 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668804 Common asd aspartate-semialdehyde dehydrogenase HQ2908A 201 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 110667380 Common aldH aldehyde dehydrogenase (succinate-semialdehyde dehydrogenase homolog) HQ1418A 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110667389 Common - hypothetical protein HQ1427A 21 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 110667281 Common trkA Trk-type potassium transport system, NAD-binding subunit HQ1314A 128 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110667095 Common epf mRNA cleavage and polyadenylation specificity factor homolog HQ1121A 149 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 110668958 Nonpathogen - hypothetical protein HQ3071A 13 COG2450 COG2450, Uncharacterized conserved protein Function unknown 110667035 Nonpathogen - hypothetical protein HQ1059A 8 None None None 110668492 Common cyaB adenylate cyclase HQ2585A 32 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 110668602 Nonpathogen - hypothetical protein HQ2699A 4 None None None 110667904 Common mntH NRAMP-family transporter (probable substrate manganese) HQ1954A 34 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 110667251 Nonpathogen rpoP DNA-directed RNA polymerase subunit P HQ1284A 11 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 110667455 Common abcP ABC-type transport system permease protein HQ1494A 14 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 110667838 Common ubiA prenyltransferase HQ1884A 60 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 110668609 Common leuB 3-isopropylmalate dehydrogenase HQ2707A 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 110668940 Common crcB protein crcB homolog HQ3052A 10 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 110668533 Nonpathogen - hypothetical protein HQ2627A 10 COG4801 COG4801, Predicted acyltransferase General function prediction only 110668162 Nonpathogen - hypothetical protein HQ2224A 3 None None None 110669249 Common nuc endonuclease Staphylococcal nuclease-like HQ3375A 27 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 110669317 Common glnK nitrogen regulatory protein P-II HQ3445A 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 110667026 Common pheS phenylalanyl-tRNA synthetase subunit alpha HQ1049A 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 110667123 Nonpathogen - hypothetical protein HQ1149A 3 None None None 110669290 Nonpathogen - divalent cation transporter, subunit II, MgtE family protein HQ3416A 16 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 110668415 Nonpathogen tatA sec-independent protein translocase component TatA HQ2505A 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 110668104 Common - hypothetical protein HQ2164A 37 None None None 110668596 Common - glycosyltransferase HQ2692A 62 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 110667136 Common - hypothetical protein HQ1162A 8 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 110669572 Common uspA probable stress response protein HQ3723A 93 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110669555 Nonpathogen grx probable glutaredoxin HQ3706A 5 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110668287 Common panD Aspartate 1-decarboxylase precursor (Aspartate alpha-decarboxylase) HQ2363A 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 110666994 Common crtY lycopene cyclase HQ1018A 8 None None None 110668460 Common lctP L-lactate permease HQ2551A 99 COG1620 LldP, L-lactate permease Energy production and conversion 110669363 Nonpathogen - hypothetical protein HQ3500A 3 None None None 110668468 Common - thioredoxin domain containing protein HQ2559A 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 110667528 Nonpathogen dnaJ Chaperone protein DnaJ HQ1569A 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110668277 Common kchA Kef-type potassium channel protein HQ2351A 126 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110667357 Common pgk phosphoglycerate kinase HQ1395A 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 110668575 Common - hypothetical protein HQ2669A 73 COG1259 COG1259, Uncharacterized conserved protein Function unknown 110668243 Nonpathogen - hypothetical protein HQ2312A 3 None None None 110667242 Common - glutathione S-transferase HQ1275A 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110669078 Common guaAb GMP synthase subunit B HQ3194A 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 110669254 Common potC ABC-type spermidine/putrescine transport system,permease protein II HQ3380A 163 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110667779 Nonpathogen - hypothetical protein HQ1824A 1 None None None 110669401 Common aslA probable arylsulfatase HQ3540A 87 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110667660 Nonpathogen - hypothetical protein HQ1703A 1 None None None 110667860 Nonpathogen - hypothetical protein HQ1908A 3 None None None 110669509 Nonpathogen - hypothetical protein HQ3659A 3 None None None 110668087 Nonpathogen - hypothetical protein HQ2146A 1 None None None 110669423 Common - hypothetical protein HQ3564A 10 COG4190 COG4190, Predicted transcriptional regulator Transcription 110669081 Common pepC Phosphoenolpyruvate carboxylase HQ3197A 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 110667572 Nonpathogen usp homolog to stress response protein HQ1613A 18 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110668130 Common - acetamidase/formamidase family protein HQ2191A 63 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 110668524 Nonpathogen - hypothetical protein HQ2618A 4 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 110669308 Common dinG Rad3-related DNA helicases DinG HQ3436A 20 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 110669543 Nonpathogen - hypothetical protein HQ3693A 1 None None None 110668328 Nonpathogen - predicted transporter (predicted permease) HQ2406A 16 COG0628 PerM, Predicted permease General function prediction only 110667950 Common fdx ferredoxin (2Fe-2S) HQ2001A 62 COG0633 Fdx, Ferredoxin Energy production and conversion 110669450 Nonpathogen - hypothetical protein HQ3594A 2 None None None 110668297 Common trxA thioredoxin HQ2374A 23 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 110669344 Nonpathogen lolE ABC-type transport system, permease protein II similar to LolDCE lipoprotein release factor HQ3476A 1 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 110668114 Nonpathogen - hypothetical protein HQ2175A 2 None None None 110667142 Common - S-adenosylmethionine-dependent methyltransferase homolog HQ1168A 180 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110668859 Nonpathogen - hypothetical protein HQ2966A 4 None None None 110668360 Nonpathogen - hypothetical protein HQ2443A 1 None None None 110666996 Common - probable nuclease domain protein/ probable ATP-dependent RNA helicase HQ1020A 206 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 110668340 Nonpathogen rad2 flap endonuclease-1 HQ2418A 35 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 110667658 Common rad50 chromosome segregation protein HQ1701A 227 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 110668396 Nonpathogen - hypothetical protein HQ2484A 2 None None None 110668220 Common - thiosulfate sulfurtransferase homolog/ hydrolase (probable hydroxyacylglutathione hydrolase) HQ2288A 95 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110669563 Common argX probable arginine biosynthesis regulator (lysine biosynthesis regulator lysX homolog) HQ3714A 103 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 110667178 Common csg cell surface glycoprotein precursor HQ1206A 10 None None None 110669489 Common - hypothetical protein HQ3639A 115 COG2855 COG2855, Predicted membrane protein Function unknown 110668942 Common - hypothetical protein HQ3054A 18 COG0433 COG0433, Predicted ATPase General function prediction only 110668753 Nonpathogen - hypothetical protein HQ2855A 3 None None None 110669476 Common ureB urease subunit beta HQ3625A 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 110668912 Common qor NADPH:quinone reductase HQ3024A 202 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110668355 Nonpathogen - hypothetical protein HQ2437A 2 None None None 110668507 Common phnH Phosphonate metabolism protein PhnH HQ2600A 17 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 110667854 Nonpathogen - hypothetical protein HQ1902A 2 None None None 110668026 Nonpathogen - hypothetical protein HQ2081A 1 None None None 110667743 Nonpathogen - hypothetical protein HQ1789A 1 None None None 110668007 Common ldcA LD-carboxypeptidase HQ2062A 34 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 110669009 Common ppiA peptidylprolyl isomerase HQ3123A 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110667530 Nonpathogen - hypothetical protein HQ1571A 1 None None None 110668263 Nonpathogen - hypothetical protein HQ2337A 1 None None None 110667881 Common cutA probable divalent divalent cation tolerance protein HQ1931A 86 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 110667998 Common - signal-transducing histidine kinase; response regulator; PAS/PAC domain protein HQ2053A 190 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 110667467 Common - hypothetical protein HQ1506A 66 COG1432 COG1432, Uncharacterized conserved protein Function unknown 110668057 Common - hypothetical protein HQ2112A 7 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110668667 Nonpathogen - hypothetical protein HQ2766A 20 COG1422 COG1422, Predicted membrane protein Function unknown 110669002 Nonpathogen dcd deoxyuridine 5'-triphosphate nucleotidohydrolase HQ3116A 26 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 110667434 Common prt phosphoribosyltransferase HQ1473A 72 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 110668846 Nonpathogen - cell division control protein cdc6 homolog HQ2953A 28 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110667789 Common cbiT precorrin-8W decarboxylase HQ1834A 66 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 110667931 Nonpathogen - transposase HQ1983A 6 None None None 110669467 Common urtD ABC-type urea transport system, ATP-binding protein I HQ3616A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110668776 Common hemK protein methyltransferase HQ2879A 37 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 110669014 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase HQ3128A 16 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 110668902 Common citG triphosphoribosyl-dephospho-CoA synthase HQ3014A 28 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 110669187 Nonpathogen rps8R 30S ribosomal protein S8e HQ3309A 34 COG2007 RPS8A, Ribosomal protein S8E Translation, ribosomal structure and biogenesis 110669495 Nonpathogen - hypothetical protein HQ3645A 4 None None None 110668441 Nonpathogen - hypothetical protein HQ2532A 1 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 110669223 Nonpathogen tif5A translation initiation factor IF-5A HQ3348A 34 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 110669265 Common rps12P 30S ribosomal protein S12P HQ3391A 153 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 110668376 Common - Tn5-like transposase HQ2460A 27 None None None 110668739 Nonpathogen rplW 50S ribosomal protein L23 HQ2840A 33 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 110669071 Common fdh formaldehyde dehydrogenase HQ3187A 200 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110668280 Nonpathogen - hypothetical protein HQ2355A 4 None None None 110668798 Nonpathogen rpl12p 50S ribosomal protein L12P HQ2901A 30 COG2058 RPP1A, Ribosomal protein L12E/L44/L45/RPP1/RPP2 Translation, ribosomal structure and biogenesis 110669386 Nonpathogen - hypothetical protein HQ3525A 1 None None None 110668382 Nonpathogen - hypothetical protein HQ2466A 3 None None None 110669375 Nonpathogen - hypothetical protein HQ3513A 6 None None None 110667041 Nonpathogen usp homolog to stress response protein HQ1065A 12 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667893 Common coxS aerobic-type carbon monoxide dehydrogenase,small subunit HQ1943A 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 110668111 Nonpathogen - hypothetical protein HQ2172A 2 None None None 110669449 Nonpathogen - hypothetical protein HQ3593A 16 COG4743 COG4743, Predicted membrane protein Function unknown 110667947 Nonpathogen dcd deoxycytidine triphosphate deaminase HQ1998A 4 None None None 110668700 Common dnaJ chaperone protein dnaJ HQ2801A 149 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110668239 Nonpathogen - hypothetical protein HQ2308A 5 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 110667786 Common cbiG cobalamin biosynthesis protein CbiG HQ1831A 73 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 110668678 Nonpathogen - hypothetical protein HQ2778A 2 None None None 110667244 Nonpathogen - hypothetical protein HQ1277A 26 COG1992 COG1992, Uncharacterized conserved protein Function unknown 110668850 Nonpathogen - hypothetical protein HQ2957A 1 None None None 110667218 Nonpathogen - GtrA-like family protein, probable cell surface polysaccharide biosynthesis protein HQ1249A 6 COG2246 COG2246, Predicted membrane protein Function unknown 110669139 Nonpathogen - hypothetical protein HQ3258A 1 None None None 110669273 Nonpathogen tif1A1 translation initiation factor IF-1A HQ3399A 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 110668720 Nonpathogen rpl30p 50S ribosomal protein L30P HQ2821A 33 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 110668581 Common gpdA glycerol-3-phosphate dehydrogenase, subunit A HQ2675A 150 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110668347 Nonpathogen gch3 GTP cyclohydrolase III HQ2427A 15 COG2429 COG2429, Uncharacterized conserved protein Function unknown 110668680 Nonpathogen - hypothetical protein HQ2780A 2 COG4347 COG4347, Predicted membrane protein Function unknown 110667873 Nonpathogen - hypothetical protein HQ1922A 2 None None None 110667887 Common - transcription regulator HQ1937A 118 COG1414 IclR, Transcriptional regulator Transcription 110669452 Nonpathogen - hypothetical protein HQ3596A 1 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 110668338 Common ubiE Menaquinone biosynthesis methyltransferase UbiE HQ2416A 26 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110668173 Nonpathogen - hypothetical protein HQ2235A 4 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110668671 Nonpathogen - hypothetical protein HQ2770A 2 None None None 110668837 Common rps13p 30S ribosomal protein S13P HQ2944A 186 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 110667605 Common nuoM NADH dehydrogenase, subunit M (ubiquinone) HQ1647A 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 110667222 Nonpathogen rpl44e 50S ribosomal protein L44e HQ1253A 30 COG1631 RPL42A, Ribosomal protein L44E Translation, ribosomal structure and biogenesis 110668619 Common bcp peroxiredoxin (thioredoxin-dependent hydroperoxide peroxidase) HQ2717A 209 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110667763 Common - hypothetical protein HQ1809A 59 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110668200 Nonpathogen - hypothetical protein HQ2264A 1 None None None 110667768 Common salX ABC-type antimicrobial peptide transport system,ATP-binding protein HQ1814A 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110667672 Common proS prolyl-tRNA synthetase HQ1715A 244 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110669323 Common hemD uroporphyrinogen-III synthase HQ3452A 83 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 110668147 Nonpathogen - hypothetical protein HQ2209A 1 None None None 110667687 Common - hypothetical protein HQ1732A 10 None None None 110668193 Common - hypothetical protein HQ2257A 29 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 110667293 Common tadA type II/IV secretion system protein, ATP binding protein HQ1328A 173 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 110668146 Common - hypothetical protein HQ2208A 56 COG3174 COG3174, Predicted membrane protein Function unknown 110668117 Common rad25 DNA repair helicase RAD25 HQ2178A 125 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 110668883 Common sdhB succinate dehydrogenase, subunit B (iron-sulfur protein) HQ2995A 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 110668066 Nonpathogen - hypothetical protein HQ2123A 2 None None None 110668191 Common - hypothetical protein HQ2255A 104 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 110667487 Common mgsA methylglyoxal synthase HQ1527A 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 110668536 Common ssuA ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component; putative aliphatic sulfonate binding protein HQ2630A 36 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110669167 Nonpathogen - hypothetical protein HQ3286A 1 None None None 110668219 Nonpathogen - hypothetical protein HQ2287A 3 None None None 110668631 Common rfcB replication factor C large subunit HQ2729A 72 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 110667374 Nonpathogen - conserved cobalamine operon protein; predicted hydrolase HQ1412A 7 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110667679 Common hcpE 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; probable 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase HQ1722A 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110668695 Common uspA probable stress response protein HQ2796A 58 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667046 Nonpathogen rps6R 30S ribosomal protein S6e HQ1070A 34 COG2125 RPS6A, Ribosomal protein S6E (S10) Translation, ribosomal structure and biogenesis 110668731 Common rpl14p 50S ribosomal protein L14P HQ2832A 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 110669180 Common livG ABC-type branched-chain amino acid transport systems, AT-binding protein I HQ3300A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667158 Nonpathogen - hypothetical protein HQ1185A 3 None None None 110668456 Nonpathogen - hypothetical protein HQ2547A 3 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 110667171 Nonpathogen - hypothetical protein HQ1199A 1 None None None 110668770 Nonpathogen - hypothetical protein HQ2872A 4 None None None 110667426 Common suhB probable inositol-1(or 4)-monophosphatase/ fructose-1,6-bisphosphatase,archaeal type HQ1465A 241 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 110668758 Common crtB geranylgeranyl-diphosphate geranylgeranyltransferase (phytoene synthase) HQ2860A 101 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 110667075 Nonpathogen - hypothetical protein HQ1100A 9 None None None 110667934 Common - major facilitator superfamily transporter HQ1986A 105 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110668785 Common gltX glutamyl-tRNA synthetase HQ2888A 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110669165 Nonpathogen htpX protease htpX protein homolog HQ3284A 1 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 110667018 Nonpathogen - transcription regulator HQ1041A 11 COG3355 COG3355, Predicted transcriptional regulator Transcription 110668787 Common - predicted hydrolase HQ2890A 150 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 110667273 Common dppF ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein II HQ1306A 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110667416 Common kdgK 2-keto-3-deoxygluconate kinase HQ1455A 142 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110669319 Common hemL glutamate-1-semialdehyde 2,1-aminomutase HQ3447A 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 110667194 Nonpathogen - probable protease HQ1224A 3 None None None 110668612 Common gatY fructose/tagatose-1,6-bisphosphate aldolase HQ2710A 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 110668401 Nonpathogen - hypothetical protein HQ2490A 9 COG4044 COG4044, Uncharacterized protein conserved in archaea Function unknown 110668078 Nonpathogen - hypothetical protein HQ2135A 1 None None None 110669417 Common - probable sulfatase HQ3556A 77 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 110666986 Nonpathogen - hypothetical protein HQ1010A 2 None None None 110669088 Nonpathogen - hypothetical protein HQ3204A 4 COG1967 COG1967, Predicted membrane protein Function unknown 110667545 Common dpsA DNA-binding protein, ferretin-like domain protein HQ1586A 48 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 110668548 Nonpathogen - hypothetical protein HQ2642A 4 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110669368 Nonpathogen - hypothetical protein HQ3506A 3 None None None 110668869 Nonpathogen - hypothetical protein HQ2978A 2 None None None 110667627 Common graD sugar nucleotidyltransferase (probable glucose-1-phosphate thymidylyltransferase) HQ1670A 201 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 110667115 Nonpathogen - hypothetical protein HQ1141A 2 None None None 110669575 Nonpathogen - hypothetical protein HQ3726A 1 None None None 110668710 Nonpathogen - hypothetical protein HQ2811A 1 None None None 110667732 Common parA parA domain protein (chromosome partitioning protein) (ATPase) HQ1778A 195 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110668308 Nonpathogen - hypothetical protein HQ2385A 4 None None None 110667995 Common apt adenine phosphoribosyltransferase HQ2050A 161 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110669439 Nonpathogen - hypothetical protein HQ3582A 2 None None None 110667055 Nonpathogen - prophage maintenance system killer protein homolog HQ1079A 1 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 110669301 Common nifS cysteine desulfurase, class V aminotransferase HQ3427A 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110667209 Nonpathogen - hypothetical protein HQ1240A 15 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110667774 Common - hypothetical protein HQ1819A 195 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110667642 Common trkA potassium transporter peripheral membrane component HQ1685A 160 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110667833 Common pyrB aspartate carbamoyltransferase catalytic subunit HQ1879A 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 110668256 Nonpathogen - hypothetical protein HQ2330A 1 None None None 110668939 Nonpathogen - probable ribosomal RNA assembly protein HQ3051A 34 COG1094 COG1094, Predicted RNA-binding protein (contains KH domains) General function prediction only 110667513 Nonpathogen - hypothetical protein HQ1554A 3 None None None 110668719 Nonpathogen rpl15p 50S ribosomal protein L15P HQ2820A 15 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 110667139 Common - conserved nad operon protein HQ1165A 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 110668824 Nonpathogen - hypothetical protein HQ2931A 4 None None None 110667992 Common trzA Atrazine chlorohydrolase HQ2047A 74 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110669043 Common mutS2 DNA mismatch repair protein HQ3158A 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110667365 Nonpathogen minD cell division inhibitor MinD HQ1403A 14 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110668035 Nonpathogen - hypothetical protein HQ2090A 2 COG5378 COG5378, Predicted nucleotide-binding protein General function prediction only 110669515 Common cbiO ABC-type transport system ATP-binding protein (probable substrate cobalt) HQ3665A 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110668367 Common rbsA ABC-type ribose transport system, ATP-binding protein HQ2451A 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 110667964 Nonpathogen - hypothetical protein HQ2016A 1 None None None 110668137 Nonpathogen - homolog to transcription regulator HQ2198A 4 None None None 110668689 Common folD methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase HQ2790A 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 110668832 Common rpl13p 50S ribosomal protein L13P HQ2939A 49 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 110667303 Nonpathogen - conserved rpo operon protein HQ1339A 30 COG1909 COG1909, Uncharacterized protein conserved in archaea Function unknown 110669100 Common nadA quinolinate synthetase HQ3216A 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 110669105 Nonpathogen - hypothetical protein HQ3223A 1 None None None 110667011 Nonpathogen - hypothetical protein HQ1034A 10 None None None 110668793 Nonpathogen rpl21R 50S ribosomal protein L21e HQ2896A 33 COG2139 RPL21A, Ribosomal protein L21E Translation, ribosomal structure and biogenesis 110669214 Common hemA glutamyl-tRNA reductase HQ3336A 181 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 110668241 Common phaC Poly-beta-hydroxybutyrate polymerase Polyhydroxyalkanoic acid synthase PhaC HQ2310A 81 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 110668187 Nonpathogen - hypothetical protein HQ2251A 1 None None None 110669035 Common engB GTP-binding protein HQ3150A 160 COG0218 COG0218, Predicted GTPase General function prediction only 110668248 Nonpathogen - transposase homolog (ISHnew96) HQ2319A 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667031 Nonpathogen - nonhistone chromosomal protein HQ1054A 8 None None None 110667652 Common hisF imidazoleglycerol-phosphate synthase chain hisF HQ1695A 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 110667104 Common fdhAII NADH:ubiquinone oxidoreductase / formate dehydrogenase alpha subunit II HQ1130A 203 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110667803 Nonpathogen - hypothetical protein HQ1848A 1 None None None 110667802 Common - putative acetamidase/formamidase HQ1847A 46 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 110669414 Nonpathogen - probable transposase (ISH8/ISH26) HQ3553A 6 None None None 110667775 Common - probable short chain dehydrogenase/ reductase HQ1820A 72 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110669059 Nonpathogen - hypothetical protein HQ3174A 7 None None None 110668274 Nonpathogen - hypothetical protein HQ2348A 1 None None None 110668358 Common sdhA succinate dehydrogenase, subunit A (flavoprotein) HQ2441A 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110668151 Common narB nitrate reductase, catalytic subunit HQ2213A 185 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110667121 Common pch voltage-gated potassium channel (MVP) HQ1147A 102 None None None 110668115 Nonpathogen - hypothetical protein HQ2176A 2 None None None 110667186 Common - probable stress response protein HQ1216A 95 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110668106 Nonpathogen - hypothetical protein HQ2167A 5 COG1414 IclR, Transcriptional regulator Transcription 110668249 Nonpathogen - hypothetical protein HQ2323A 2 None None None 110669421 Nonpathogen - hypothetical protein HQ3561A 1 None None None 110668462 Nonpathogen - hypothetical protein (probable membrane protein) HQ2553A 1 None None None 110667180 Common sub subtilisin-like serine protease HQ1208A 16 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110668936 Nonpathogen coaE dephospho-CoA kinase HQ3047A 34 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 110666992 Nonpathogen ferC ferredoxin III HQ1016A 4 COG1141 Fer, Ferredoxin Energy production and conversion 110668055 Nonpathogen - hypothetical protein HQ2110A 1 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 110667068 Common - predicted oxidoreductase, aldo/keto reductase family HQ1093A 195 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110667984 Nonpathogen - hypothetical protein HQ2037A 1 None None None 110669345 Nonpathogen lolC ABC-type transport system, permease protein I similar to LolDCE lipoprotein release factor HQ3477A 6 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 110669429 Nonpathogen - hypothetical protein HQ3572A 2 None None None 110668168 Common sugE small multidrug export protein HQ2230A 125 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 110668738 Common rpl2p 50S ribosomal protein L2P HQ2839A 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 110669340 Nonpathogen - transposase HQ3472A 1 None None None 110667187 Nonpathogen - hypothetical protein HQ1217A 20 COG3379 COG3379, Uncharacterized conserved protein Function unknown 110666995 Nonpathogen brp brp-like protein HQ1019A 7 None None None 110669076 Nonpathogen - hypothetical protein HQ3192A 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 110669578 Common cysA thiosulfate sulfurtransferase HQ3729A 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110669212 Common nirH heme biosynthesis protein nirH/G (nirL/nirD homolog) HQ3334A 51 COG1522 Lrp, Transcriptional regulators Transcription 110668582 Common - hypothetical protein HQ2676A 106 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 110668732 Common rps17p 30S ribosomal protein S17P HQ2833A 156 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 110667054 Nonpathogen - hypothetical protein HQ1078A 3 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 110667130 Common fba fructose-bisphosphate aldolase HQ1156A 88 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 110667085 Common pepF oligoendopeptidase HQ1110A 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 110669458 Common bcp peroxiredoxin HQ3602A 53 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110668227 Common cobN cobalt chelatase HQ2296A 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 110667923 Common tauA ABC-type nitrate/sulfonate/bicarbonate transport system, substrate binding protein HQ1974A 5 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110669541 Nonpathogen - hypothetical protein HQ3691A 14 COG2259 COG2259, Predicted membrane protein Function unknown 110669039 Common mer methylenetetrahydromethanopterin reductase HQ3154A 58 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110667382 Common pkn RIO-like serine/threonine protein kinase HQ1420A 62 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 110668417 Nonpathogen - hypothetical protein HQ2507A 2 None None None 110667105 Nonpathogen - hypothetical protein HQ1131A 1 None None None 110668863 Nonpathogen - hypothetical protein HQ2971A 1 COG2442 COG2442, Uncharacterized conserved protein Function unknown 110668962 Nonpathogen - hypothetical protein HQ3075A 12 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110667598 Common nuoCD NADH dehydrogenase, subunit CD (ubiquinone) HQ1639A 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 110667564 Common glo lyase/ dioxygenase (probable lactoylglutathione lyase, aromatic compounds dioxygenase) HQ1605A 120 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110668984 Common secF preprotein translocase subunit SecF HQ3098A 77 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 110669477 Common ureC urease subunit alpha HQ3626A 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 110668453 Common sfuB ABC-type iron(III) transport system, permease protein HQ2544A 213 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110668201 Nonpathogen - possible pyridoxamine 5'-phosphate oxidase HQ2265A 2 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 110667005 Common - hypothetical protein HQ1028A 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 110669354 Nonpathogen - hypothetical protein HQ3486A 10 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 110668921 Nonpathogen - conserved cobalamin operon protein HQ3032B 4 None None None 110669137 Nonpathogen - hypothetical protein HQ3256A 29 COG2237 COG2237, Predicted membrane protein Function unknown 110668438 Nonpathogen - hypothetical protein HQ2529A 5 None None None 110669084 Nonpathogen - hypothetical protein HQ3200A 3 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 110667625 Common cysD sulfate adenylyltransferase, small subunit HQ1668A 109 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 110667700 Nonpathogen - hypothetical protein HQ1746A 2 None None None 110668590 Nonpathogen - hypothetical protein HQ2685A 3 None None None 110667204 Common - probable short chain dehydrogenase/ reductase HQ1235A 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110668172 Nonpathogen - hypothetical protein HQ2234A 4 None None None 110669264 Common rps7 30S ribosomal protein S7P HQ3390A 138 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 110668233 Common hbd 3-hydroxyacyl-CoA dehydrogenase HQ2302A 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110668773 Nonpathogen - hypothetical protein HQ2876A 1 None None None 110667899 Nonpathogen - probable transcription regulator,ArsR family HQ1949A 4 None None None 110668882 Common sdhA succinate dehydrogenase, subunit A (flavoprotein) HQ2994A 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110667368 Nonpathogen cbiZ Adenosylcobinamide amidohydrolase (AdoCbi hydrolase) HQ1406A 4 COG1865 COG1865, Uncharacterized conserved protein Function unknown 110669231 Common porA pyruvate--ferredoxin oxidoreductase, alpha subunit HQ3356A 109 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 110667424 Nonpathogen - hypothetical protein HQ1463A 2 COG2510 COG2510, Predicted membrane protein Function unknown 110668643 Nonpathogen - hypothetical protein HQ2742A 1 None None None 110669552 Nonpathogen - hypothetical protein HQ3703A 1 None None None 110667289 Common trxA thioredoxin HQ1323A 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110669302 Common nifU homolog to nitrogen fixation protein NifU HQ3428A 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 110667444 Common dppD ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein I HQ1483A 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110668803 Common accA2 biotin carboxylase 1, acyl-CoA carboxylase, alpha subunit 2 HQ2906A 232 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 110668673 Common idiA isopentenyl-diphosphate delta-isomerase HQ2772A 43 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 110667468 Common dapA dihydrodipicolinate synthase HQ1507A 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110667498 Common - probable substrate efflux/proton antiporter HQ1539A 49 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 110668089 Nonpathogen - hypothetical protein HQ2148A 3 None None None 110668577 Common ileS isoleucyl-tRNA synthetase HQ2671A 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667315 Nonpathogen - hypothetical protein HQ1351A 1 None None None 110667335 Common - probable stress response protein HQ1373A 72 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110669032 Common ftsZ cell division protein ftsZ HQ3147A 119 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 110667496 Nonpathogen - electron transfer protein homolog HQ1537A 9 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 110668409 Common - hexosyltransferase HQ2499A 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667977 Nonpathogen - ISH9-type transposase HQ2030A 5 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 110668118 Nonpathogen - hypothetical protein HQ2179A 1 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667063 Nonpathogen - hypothetical protein HQ1087A 2 None None None 110668493 Common mtfK2 FKBP-type peptidylprolyl isomerase 2 HQ2586A 126 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 110669374 Common - probable SAM-dependent methyltransferase HQ3512A 8 None None None 110669157 Common hepA ATP-dependent helicase HepA HQ3276A 166 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 110669222 Common ubiB probable ubiquinone biosynthesis transmembrane protein HQ3347A 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 110667748 Common crtI phytoene dehydrogenase (phytoene desaturase) HQ1794A 101 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110667588 Common trxA thioredoxin HQ1629A 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110668097 Nonpathogen - hypothetical protein HQ2157A 4 COG3355 COG3355, Predicted transcriptional regulator Transcription 110668101 Nonpathogen - hypothetical protein HQ2161A 2 None None None 110667940 Common ugpB ABC-type sugar/sn-glycerol-3-phosphate transport system, periplasmic protein HQ1992A 5 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110668424 Nonpathogen - IS1341-type transposase homolog HQ2515A 2 None None None 110667863 Common malA alpha-glucosidases, family 31 of glycosyl hydrolases HQ1911A 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 110668759 Common - probable carotenoid biosynthesis protein HQ2861A 13 COG2324 COG2324, Predicted membrane protein Function unknown 110668981 Nonpathogen - hypothetical protein HQ3095A 33 COG1258 COG1258, Predicted pseudouridylate synthase Translation, ribosomal structure and biogenesis 110667669 Common - hypothetical protein HQ1712A 27 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 110668404 Common dadA glycine/D-amino acid oxidases (deaminating) HQ2493A 11 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110667614 Nonpathogen cbiX hypothetical protein HQ1656A 11 COG2138 COG2138, Uncharacterized conserved protein Function unknown 110669095 Common dsbA thioredoxin; DsbA oxidoreductase HQ3211A 45 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 110669387 Nonpathogen bcbD capsular protein HQ3526A 1 None None None 110668012 Nonpathogen - hypothetical protein HQ2067A 1 None None None 110667646 Nonpathogen tfbA transcription initiation factor TFB HQ1689A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667722 Common fhs formyltetrahydrofolate synthetase HQ1768A 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 110669522 Nonpathogen - probable acetyltransferase (GNAT) family HQ3672A 2 None None None 110667473 Common dapE succinyl-diaminopimelate desuccinylase HQ1512A 91 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110669063 Nonpathogen - hypothetical protein HQ3179A 3 None None None 110667828 Common menB naphthoate synthase HQ1874A 171 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 110669257 Common potD ABC-type spermidine/putrescine transport system,substrate-binding protein HQ3383A 93 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110668593 Nonpathogen - hypothetical protein HQ2688A 2 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 110668764 Nonpathogen - metalloenzyme, probable TatD related DNAse HQ2866A 26 COG1831 COG1831, Predicted metal-dependent hydrolase (urease superfamily) General function prediction only 110668774 Common - hypothetical protein HQ2877A 22 COG2322 COG2322, Predicted membrane protein Function unknown 110669113 Common - hypothetical protein HQ3231A 65 COG2928 COG2928, Uncharacterized conserved protein Function unknown 110667521 Common - hypothetical protein HQ1562A 21 COG2119 COG2119, Predicted membrane protein Function unknown 110668831 Common rps9p 30S ribosomal protein S9P HQ2938A 237 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 110668080 Nonpathogen - hypothetical protein HQ2137A 4 None None None 110669502 Nonpathogen minD probable cell division inhibitor HQ3652A 3 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110669193 Common fxsA FxsA HQ3315A 9 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 110668750 Common dhs putative deoxyhypusine synthase HQ2852A 59 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 110668074 Nonpathogen - hypothetical protein HQ2131A 3 COG2886 COG2886, Uncharacterized small protein Function unknown 110668048 Nonpathogen - hypothetical protein HQ2103A 1 None None None 110667636 Common phaC putative monovalent cation/H+ antiporter subunit C HQ1679A 100 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 110668998 Common gcvT aminomethyltransferase, glycin cleavage system T protein HQ3112A 165 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 110669025 Common - GTP-binding protein HQ3140A 159 COG1084 COG1084, Predicted GTPase General function prediction only 110669372 Common galE nucleoside-diphosphate-sugar epimerase (probable UDP-glucose 4-epimerase) HQ3510A 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110667413 Nonpathogen - hypothetical protein HQ1452A 3 None None None 110667594 Common purK phosphoribosylaminoimidazole carboxylase carbon dioxide-fixation chain HQ1635A 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 110667043 Nonpathogen - hypothetical protein HQ1067A 11 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 110667298 Nonpathogen - hypothetical protein HQ1334A 1 None None None 110669487 Common arsC probable arsenate reductase (glutaredoxin); probable protein-tyrosine-phosphatase HQ3636A 67 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110668294 Common - hypothetical protein HQ2371A 25 COG3358 COG3358, Uncharacterized conserved protein Function unknown 110667716 Common ilvA threonine ammonia-lyase HQ1762A 225 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110668893 Common - succinylglutamate desuccinylase homolog HQ3005A 10 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 110667278 Nonpathogen - hypothetical protein HQ1311A 1 None None None 110667913 Nonpathogen - hypothetical protein HQ1963A 1 None None None 110667266 Common - predicted F420-dependent NADP reductase HQ1299A 33 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 110668509 Common phnJ Phosphonate metabolism protein PhnJ HQ2602A 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 110669204 Common panF sodium/pantothenate symporter HQ3326A 149 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 110669242 Common hcpE 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; probable 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase HQ3367A 182 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110669052 Common trpE anthranilate synthase, component I HQ3167A 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 110668410 Common - hexosyltransferase 1 HQ2500A 133 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667563 Nonpathogen - hypothetical protein HQ1604A 13 COG4083 COG4083, Predicted membrane protein Function unknown 110668065 Nonpathogen - hypothetical protein HQ2122A 1 None None None 110667486 Common ndh NADH dehydrogenase HQ1526A 107 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 110667375 Nonpathogen - hypothetical protein HQ1413A 6 None None None 110667407 Common phr deoxyribodipyrimidine photolyase HQ1445A 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 110669503 Nonpathogen - hypothetical protein HQ3653A 4 None None None 110668815 Common msrB peptide methionine sulfoxide reductase (R-form specific) HQ2921A 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110666979 Nonpathogen polA1 DNA polymerase II small subunit HQ1003A 24 COG1311 HYS2, Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B DNA replication, recombination, and repair 110669311 Nonpathogen - hypothetical protein HQ3439A 4 None None None 110667324 Nonpathogen - hypothetical protein HQ1361A 28 COG0622 COG0622, Predicted phosphoesterase General function prediction only 110667505 Nonpathogen - hypothetical protein HQ1546A 3 None None None 110667017 Nonpathogen - hypothetical protein HQ1040A 4 None None None 110668443 Nonpathogen - hypothetical protein HQ2534A 1 None None None 110667113 Nonpathogen - hypothetical protein HQ1139A 1 None None None 110668712 Nonpathogen - hypothetical protein HQ2813A 2 None None None 110668052 Nonpathogen - hypothetical protein HQ2107A 1 None None None 110668309 Nonpathogen - hypothetical protein HQ2386A 1 None None None 110667933 Common acaB acetyl-CoA C-acyltransferase HQ1985A 114 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110667952 Nonpathogen - hypothetical protein HQ2003A 1 None None None 110667048 Nonpathogen - hypothetical protein HQ1072A 1 None None None 110667175 Common - hypothetical protein HQ1203A 21 COG1430 COG1430, Uncharacterized conserved protein Function unknown 110667377 Common ftsZ cell division protein FtsZ HQ1415A 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 110667997 Common pitA phosphate permease homolog HQ2052A 35 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 110669207 Nonpathogen - hypothetical protein HQ3329A 1 COG0456 RimI, Acetyltransferases General function prediction only 110667793 Common cbiO CbiO protein ( probable ABC-type cobalt transport system ATP-binding protein) HQ1838A 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110668302 Common ugpQ glycerophosphodiester phosphodiesterase HQ2379A 132 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110668135 Common livM ABC-type branched-chain amino acid transport system, permease protein II HQ2196A 103 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110667574 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ1615A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110669544 Common uvrC excinuclease ABC chain C HQ3694A 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 110669286 Common hisG ATP phosphoribosyltransferase HQ3412A 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 110667855 Nonpathogen - hypothetical protein HQ1903A 2 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 110668914 Nonpathogen - hypothetical protein HQ3026A 3 None None None 110669174 Nonpathogen - hypothetical protein HQ3293A 1 None None None 110669330 Common - conserved polA operon protein (predicted DNA-binding protein) HQ3460A 29 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 110668687 Common - probable phosphoglycolate phosphatase HQ2788A 37 COG0546 Gph, Predicted phosphatases General function prediction only 110668276 Nonpathogen - hypothetical protein HQ2350A 9 None None None 110668517 Nonpathogen - hypothetical protein HQ2610A 3 COG3679 COG3679, Uncharacterized conserved protein Function unknown 110667349 Common thsB thermosome, beta subunit HQ1387A 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110668852 Nonpathogen cdc6_ cell division control protein cdc6 homolog HQ2959A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110669558 Common glyS glycyl-tRNA synthetase HQ3709A 87 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 110668692 Common - hypothetical protein HQ2793A 42 COG1944 COG1944, Uncharacterized conserved protein Function unknown 110667543 Common - homolog to phycocyanobilin lyase subunit HQ1584A 19 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 110669147 Nonpathogen - homolog to predicted helicase HQ3266A 17 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 110669313 Common - hypothetical protein HQ3441A 107 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110669396 Nonpathogen - hypothetical protein HQ3534A 1 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110667036 Common entB probable isochorismatase; probable nicotinamidase; probable N-carbamoylsarcosine amidase HQ1060A 144 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110667366 Common cbiP cobyric acid synthase HQ1404A 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 110667155 Common - aldo/keto reductase family protein HQ1182A 10 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110668361 Nonpathogen - hypothetical protein HQ2444A 1 None None None 110669399 Nonpathogen - hypothetical protein HQ3538A 3 None None None 110667845 Common udp uridine phosphorylase HQ1892A 31 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 110668860 Common - hypothetical protein HQ2967A 80 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 110669163 Nonpathogen - hypothetical protein HQ3282A 1 None None None 110667418 Common mutT mut/nudix family protein HQ1457A 19 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110667310 Nonpathogen csg cell surface glycoprotein precursor HQ1346A 3 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667738 Common trpE anthranilate synthase, component I HQ1784A 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 110669232 Common aroC chorismate synthase HQ3357A 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 110667759 Common cre creatinine amidohydrolase HQ1805A 89 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110667120 Common - 3-beta hydroxysteroid dehydrogenase/isomerase family HQ1146A 6 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110668630 Common - IS1341-type transposase HQ2728A 63 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668009 Common rhtB threonine/homoserine/homoserine lactone efflux protein HQ2064A 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110669465 Nonpathogen - conserved hypothetical protein (nonfunctional,N-terminal part) HQ3614A 4 None None None 110668217 Nonpathogen - hypothetical protein HQ2284A 1 None None None 110668637 Common mdh malic enzyme HQ2736A 218 COG0281 SfcA, Malic enzyme Energy production and conversion 110667549 Common acaB acetyl-CoA C-acyltransferase HQ1590A 135 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110668563 Common thiD phosphomethylpyrimidine kinase HQ2657A 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 110667411 Nonpathogen - hypothetical protein HQ1450A 2 None None None 110669304 Common - hypothetical protein HQ3430A 13 None None None 110667236 Common topA DNA topoisomerase I HQ1267A 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110669442 Nonpathogen - probable integrase (PhiCh1 Int1-like) HQ3586A 1 None None None 110668783 Nonpathogen - hypothetical protein HQ2886A 5 None None None 110667550 Nonpathogen - hypothetical protein HQ1591A 2 None None None 110669498 Common adh alcohol dehydrogenase, NAD dependent HQ3648A 203 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 110667972 Nonpathogen gapB glyceraldehyde-3-phosphate dehydrogenase HQ2025A 34 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110668145 Common sqlE probable oxidoreductase HQ2207A 23 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110667025 Common trpS tryptophanyl-tRNA synthetase HQ1048A 131 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667456 Common eda probable KHG/KDPG aldolase (4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase) HQ1495A 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 110669573 Nonpathogen - hypothetical protein HQ3724A 3 COG0730 COG0730, Predicted permeases General function prediction only 110668342 Nonpathogen - IS1341-type transposase HQ2420A 4 None None None 110667817 Nonpathogen - DNA binding protein, bacterio-opsin activator-like HQ1863A 10 COG3413 COG3413, Predicted DNA binding protein General function prediction only 110667691 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C HQ1736A 172 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 110667750 Nonpathogen - hypothetical protein HQ1796A 2 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 110667511 Nonpathogen - hypothetical protein HQ1552A 3 None None None 110667507 Common hcpE halocyanin hcpE HQ1548A 16 COG3794 PetE, Plastocyanin Energy production and conversion 110667883 Common - probable antibiotic hydrolase; X-Pro dipeptidyl-peptidase (S15 family); probable cocaine esterase HQ1933A 60 COG2936 COG2936, Predicted acyl esterases General function prediction only 110668320 Common - probable methyltransferase HQ2398A 98 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 110667215 Common - hypothetical protein HQ1246A 43 None None None 110669408 Common - hexosyltransferase; glycosyltransferase HQ3547A 12 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110668076 Nonpathogen - hypothetical protein HQ2133A 3 None None None 110668843 Nonpathogen - hypothetical protein HQ2950A 4 None None None 110667271 Nonpathogen - hypothetical protein HQ1304A 1 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 110668618 Common - AAA-type ATPase (transitional ATPase homolog) HQ2716A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110667644 Common aatA aspartyl-tRNA(Asn) amidotransferase subunit A HQ1687A 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 110668567 Common psmB proteasome beta subunit HQ2661A 48 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 110667709 Common hadL 2-haloalkanoic acid dehalogenase HQ1755A 75 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110667889 Common qor NADPH:quinone reductase HQ1939A 199 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 110668214 Common - hypothetical protein HQ2281A 22 COG2013 COG2013, Uncharacterized conserved protein Function unknown 110667344 Common phnC ABC-type phosphate/phosphonate/phosphite transport system, ATP-binding protein HQ1382A 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 110669412 Nonpathogen - transposase homolog (ISHnew96) HQ3551A 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 110667396 Common potD ABC-type spermidine/putrescine transport system,substrate-binding domain HQ1434A 91 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110668179 Common hyuA N-methylhydantoinase A (ATP-hydrolyzing) HQ2242A 119 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110667698 Common ppk polyphosphate kinase HQ1743A 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 110668282 Common hcpH halocyanin hcpH HQ2357A 16 COG3794 PetE, Plastocyanin Energy production and conversion 110669082 Nonpathogen petA probable menaquinol--cytochrome-c reductase (cytochrome bc complex) Rieske iron-sulfur protein (ubiquinol--cytochrome-c reductase (cytochrome bc1 complex) Rieske iron-sulfur protein homolog) HQ3198A 3 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 110668327 Nonpathogen rpa replication factor A HQ2405A 21 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 110669434 Nonpathogen - hypothetical protein HQ3577A 5 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110668266 Common moaC putative molybdenum cofactor biosynthesis protein C HQ2340A 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110668520 Nonpathogen - probable transposase (ISHnew91) HQ2613A 5 None None None 110668702 Nonpathogen - hypothetical protein HQ2803A 1 None None None 110668390 Common dppA ABC-type dipeptide/oligopeptide/nickel transport system, substrate-binding protein HQ2477A 194 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110668113 Nonpathogen - hypothetical protein HQ2174A 2 None None None 110668154 Nonpathogen - hypothetical protein HQ2216A 1 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110668431 Nonpathogen - protein N-acetyltransferase homolog HQ2522A 1 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110668745 Nonpathogen - hypothetical protein HQ2846A 2 COG1624 COG1624, Uncharacterized conserved protein Function unknown 110668254 Nonpathogen - hypothetical protein HQ2328A 4 None None None 110667849 Nonpathogen - hypothetical protein HQ1896A 4 None None None 110667220 Nonpathogen - hypothetical protein HQ1251A 14 COG5427 COG5427, Uncharacterized membrane protein Function unknown 110668551 Nonpathogen - hypothetical protein HQ2645A 1 None None None 110668332 Nonpathogen - hypothetical protein HQ2410A 4 None None None 110668978 Common - ABC-type transport system, permease protein HQ3092A 147 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110667714 Common gcvT aminomethyltransferase, glycin cleavage system T protein HQ1760A 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 110668822 Common lhr Lhr-like helicase HQ2928A 159 COG1201 Lhr, Lhr-like helicases General function prediction only 110668339 Nonpathogen - hypothetical protein HQ2417A 4 None None None 110667850 Nonpathogen - hypothetical protein HQ1898A 4 COG3355 COG3355, Predicted transcriptional regulator Transcription 110669279 Common rfcC replication factor C small subunit 2 HQ3405A 223 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 110669475 Common cbiO ABC-type cobalt transport system, ATP binding protein HQ3624A 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 110667673 Common epf2 mRNA 3'-end processing factor homolog HQ1716A 134 COG1782 COG1782, Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain General function prediction only 110669089 Common deoC deoxyribose-phosphate aldolase HQ3205A 113 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 110667807 Nonpathogen - probable DNA repair and recombination protein radA HQ1852A 4 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 110669440 Nonpathogen - hypothetical protein HQ3583A 4 None None None 110667249 Nonpathogen - hypothetical protein HQ1282A 8 COG4031 COG4031, Predicted metal-binding protein General function prediction only 110667680 Nonpathogen - hypothetical protein HQ1723A 2 None None None 110667460 Nonpathogen - hypothetical protein HQ1499A 3 None None None 110668818 Nonpathogen - hypothetical protein HQ2924A 1 None None None 110667536 Common ctaB protoheme IX farnesyltransferase HQ1577A 166 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 110667681 Nonpathogen - transcription regulator HQ1724A 11 COG3355 COG3355, Predicted transcriptional regulator Transcription 110667666 Nonpathogen - hypothetical protein HQ1709A 3 None None None 110667724 Nonpathogen gvpM gas-vesicle operon protein gvpM HQ1770A 5 None None None 110668315 Nonpathogen - hypothetical protein HQ2392A 4 None None None 110667896 Common - probable response regulator / probable transcription regulator HQ1946A 103 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110669125 Common atpA V-type ATP synthase subunit A HQ3244A 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 110667162 Nonpathogen - hypothetical protein HQ1189A 5 None None None 110669492 Common lrp transcription regulator AsnC family HQ3642A 127 COG1522 Lrp, Transcriptional regulators Transcription 110667966 Common salX ABC-type antimicrobial peptide transport system,ATP-binding protein HQ2018A 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110668871 Nonpathogen - hypothetical protein HQ2982A 4 None None None 110668916 Common - hypothetical protein HQ3028A 20 None None None 110668699 Common - translation elongation factor aEF-1 alpha subunit homolog HQ2800A 249 COG5258 GTPBP1, GTPase General function prediction only 110667900 Common - amino acid transporter HQ1950A 180 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 110668560 Common top6A DNA topoisomerase VI subunit A HQ2654A 34 COG1697 COG1697, DNA topoisomerase VI, subunit A DNA replication, recombination, and repair 110667132 Common trpB tryptophan synthase subunit beta HQ1158A 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 110669351 Common mutT Mut/nudix family protein HQ3483A 28 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110668501 Nonpathogen - phosphate transport system regulator related protein HQ2594A 6 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110669451 Nonpathogen - hypothetical protein HQ3595A 1 None None None 110669337 Common hmu3 probable cell surface glycoprotein HQ3467A 132 COG1572 COG1572, Uncharacterized conserved protein Function unknown 110669389 Nonpathogen - ISH9-type transposase (nonfunctional, N-terminal part) HQ3527B 4 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 110668038 Nonpathogen - hypothetical protein HQ2093A 2 None None None 110667936 Common - predicted crotonobetainyl-CoA:carnitine CoA-transferase/alpha-methylacyl-CoA racemase HQ1988A 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110669561 Common argH argininosuccinate lyase HQ3712A 228 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110667073 Common pyrH uridylate kinase HQ1098A 34 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 110668573 Common - membrane metallopeptidase HQ2667A 41 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110668124 Common dctQ TRAP-type C4-dicarboxylate transport system,small permease component HQ2185A 6 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 110668928 Nonpathogen - probable stress response protein HQ3039A 3 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110668488 Common - predicted NAD-binding protein (probable Kef-type transporter subunit) HQ2581A 81 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 110668654 Common cdc48 AAA-type ATPase (transitional ATPase homolog) HQ2753A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110669016 Common purS phosphoribosylformylglycinamidine synthase, PurS component HQ3130A 91 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 110667432 Common pstS ABC-type phosphate transport system, substrate binding protein HQ1471A 121 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 110668271 Nonpathogen - hypothetical protein HQ2345A 4 COG1414 IclR, Transcriptional regulator Transcription 110667093 Common copA transport ATPase 1 (probable substrates copper/metal cation) HQ1119A 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110666988 Common - IS1341-type transposase HQ1012A 66 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110669135 Nonpathogen - hypothetical protein HQ3254A 4 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 110667566 Common drg GTP-binding protein HQ1607A 186 COG1163 DRG, Predicted GTPase General function prediction only 110667919 Common - site-specific DNA-methyltransferase HQ1970A 117 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 110667384 Common modB ABC-type transport system, permease domain (probable substrates sulfate, thiosulfate or molybdate) HQ1422A 225 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 110668071 Common - hypothetical protein HQ2128A 23 COG2253 COG2253, Uncharacterized conserved protein Function unknown 110668727 Nonpathogen rps14P 30S ribosomal protein S14P HQ2828A 31 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 110669327 Common fdx ferredoxin (2Fe-2S) HQ3457A 62 COG0633 Fdx, Ferredoxin Energy production and conversion 110668231 Common argK transport ATPase, component for probable LAO/AO transport systems HQ2300A 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 110667765 Common lrp transcription regulator HQ1811A 118 COG1522 Lrp, Transcriptional regulators Transcription 110668451 Nonpathogen - probable membrane protein (11 TMHs) HQ2542A 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 110668591 Common - probable hexosyltransferase; glycosyltransferase HQ2686A 51 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110668926 Nonpathogen - hypothetical protein HQ3037A 1 None None None 110667925 Common tauB ABC-type nitrate/sulfonate/bicarbonate transport system, ATP-binding protein HQ1976A 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110667370 Common cobT hypothetical protein HQ1408A 40 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 110668317 Common fadA enoyl-CoA hydratase I HQ2394A 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110669150 Nonpathogen cdc6_ cell division control protein cdc6 homolog HQ3269A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110668960 Nonpathogen - hypothetical protein HQ3073A 4 None None None 110668044 Nonpathogen - hypothetical protein HQ2099A 1 None None None 110667146 Nonpathogen - hypothetical protein HQ1172A 20 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 110668737 Common rps19p 30S ribosomal protein S19P HQ2838A 165 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 110667091 Nonpathogen - hypothetical protein HQ1117A 3 None None None 110667694 Common boa bacterio-opsin activator-like transcription regulator HQ1739A 127 COG3413 COG3413, Predicted DNA binding protein General function prediction only 110669581 Common - probable S-adenosylmethionine-dependent methyltransferase (24-sterol C-methyltransferase homolog) HQ3733A 145 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110668235 Common cbiQ ABC-type cobalt transport system, permease protein II HQ2304A 24 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 110668374 Nonpathogen - hypothetical protein HQ2458A 4 None None None 110667585 Common btuD corrinoid ABC transporter ATPase HQ1626A 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110667458 Common - hypothetical protein HQ1497A 37 COG3402 COG3402, Uncharacterized conserved protein Function unknown 110669320 Common - transposase HQ3448A 12 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 110668605 Common ilvN acetolactate synthase, small subunit HQ2703A 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 110668808 Nonpathogen - probable integrase/recombinase HQ2912A 1 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110667718 Nonpathogen - hypothetical protein HQ1764A 1 None None None 110667256 Common guaAa GMP synthase subunit A HQ1289A 241 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 110669262 Common tef2 elongation factor EF-2 HQ3388A 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110667422 Common - probable short chain dehydrogenase/ reductase HQ1461A 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110668002 Common - hypothetical protein HQ2057A 6 None None None 110668067 Nonpathogen - hypothetical protein HQ2124A 2 None None None 110668170 Common - restriction system mrr homolog HQ2232A 16 COG1715 Mrr, Restriction endonuclease Defense mechanisms 110667799 Common proA glutamate-5-semialdehyde dehydrogenase HQ1844A 191 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 110668158 Nonpathogen - hypothetical protein HQ2220A 1 None None None 110667623 Nonpathogen - hypothetical protein HQ1666A 3 None None None 110669198 Nonpathogen - hypothetical protein HQ3320A 4 None None None 110667287 Nonpathogen - hypothetical protein HQ1321A 1 None None None 110668608 Common leuD 3-isopropylmalate dehydratase small subunit HQ2706A 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 110668464 Nonpathogen - hypothetical protein HQ2555A 1 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 110667405 Nonpathogen - predicted TRAP-type transport system protein HQ1443A 6 COG4729 COG4729, Uncharacterized conserved protein Function unknown 110669430 Nonpathogen - hypothetical protein HQ3573A 4 COG1846 MarR, Transcriptional regulators Transcription 110667857 Common - S-adenosylmethionine-dependent methyltransferase homolog HQ1905A 49 COG2520 COG2520, Predicted methyltransferase General function prediction only 110669007 Common nirD heme biosynthesis protein nirD/L (nirH/nirG homolog) HQ3121A 52 COG1522 Lrp, Transcriptional regulators Transcription 110667773 Nonpathogen - hypothetical protein HQ1818A 4 None None None 110669349 Nonpathogen - hypothetical protein HQ3481A 1 None None None 110668060 Nonpathogen - hypothetical protein HQ2115A 1 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 110669534 Common tatC2 sec-independent protein translocase component TatC2 HQ3684A 176 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 110668835 Common rps11p 30S ribosomal protein S11P HQ2942A 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 110667141 Nonpathogen - glycosyltransferase HQ1167A 5 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110668272 Common usp probable stress response protein HQ2346A 160 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110669427 Nonpathogen - hypothetical protein HQ3570A 4 None None None 110668206 Common - ferredoxin domain protein HQ2271A 61 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 110667654 Common - metallo-beta-lactamase family protein / hydrolase HQ1697A 105 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110669347 Nonpathogen - probable extracellular mucin like protein HQ3479A 4 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 110668247 Common leuS leucyl-tRNA synthetase HQ2317A 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110667541 Common - nitroreductase family protein HQ1582A 38 COG0778 NfnB, Nitroreductase Energy production and conversion 110667839 Nonpathogen - hypothetical protein HQ1885A 1 None None None 110667982 Common - mandelate racemase/muconate lactonizing enzyme family protein HQ2035A 143 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110668108 Nonpathogen - hypothetical protein HQ2169A 3 None None None 110669548 Common metY O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) HQ3699A 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 110669518 Common guaA guanosine monophosphate synthetase (glutamine-hydrolyzing) (GMP synthase) HQ3668A 237 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 110668495 Common - hypothetical protein HQ2588A 8 COG3679 COG3679, Uncharacterized conserved protein Function unknown 110669000 Nonpathogen pdaD pyruvoyl-dependent arginine decarboxylase HQ3114A 4 COG1945 COG1945, Uncharacterized conserved protein Function unknown 110667038 Nonpathogen - hypothetical protein HQ1062A 10 None None None 110668969 Nonpathogen - hypothetical protein HQ3083A 4 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 110667462 Nonpathogen - hypothetical protein HQ1501A 1 None None None 110668797 Nonpathogen - hypothetical protein HQ2900A 18 COG1784 COG1784, Predicted membrane protein Function unknown 110667306 Nonpathogen - hypothetical protein HQ1342A 4 None None None 110669191 Nonpathogen - hypothetical protein HQ3313A 3 None None None 110667664 Common sufB ABC-type transport system involved in Fe-S cluster assembly, permease protein I HQ1707A 185 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 110668542 Nonpathogen - hypothetical protein HQ2636A 5 None None None 110667033 Nonpathogen - hypothetical protein HQ1057A 40 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 110669074 Nonpathogen rpoM2 DNA-directed RNA polymerase subunit M2 HQ3190A 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 110669218 Common pgp probable phosphatase (phosphoglycolate phosphatase homolog) HQ3343A 27 COG0546 Gph, Predicted phosphatases General function prediction only 110667238 Common pcrB geranylgeranylglyceryl phosphate synthase-like protein HQ1269A 27 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 110668628 Common trmB probable sugar-specific transcriptional regulator TrmB HQ2726A 32 COG1378 COG1378, Predicted transcriptional regulators Transcription 110667557 Nonpathogen - hypothetical protein HQ1598A 1 None None None 110669283 Nonpathogen - hypothetical protein HQ3409A 2 None None None 110669484 Nonpathogen - hypothetical protein HQ3633A 4 None None None 162138286 Nonpathogen tif1A2 translation initiation factor IF-1A HQ1727A 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 110669520 Common alaS alanyl-tRNA synthetase HQ3670A 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110669018 Nonpathogen - hypothetical protein HQ3132A 16 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 110669505 Nonpathogen fbp probable fructose-2,6-bisphosphatase HQ3655A 6 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110668756 Common sucC succinate--CoA ligase beta subunit (ADP-forming) HQ2858A 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 110668014 Nonpathogen - hypothetical protein HQ2069A 1 None None None 110667561 Nonpathogen - hypothetical protein HQ1602A 3 None None None 110669259 Common tef1a elongation factor 1-alpha HQ3385A 249 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 110668126 Nonpathogen - hypothetical protein HQ2187A 1 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110667911 Common - CBS-domain protein HQ1961A 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110668497 Nonpathogen dph2 probable diphthamide synthase subunit DPH2 HQ2590A 34 COG1736 DPH2, Diphthamide synthase subunit DPH2 Translation, ribosomal structure and biogenesis 110668021 Nonpathogen - hypothetical protein HQ2076A 1 None None None 110667182 Nonpathogen - hypothetical protein HQ1211A 1 None None None 110669234 Common polIVy DNA-directed DNA polymerase (family Y) (archaeal DNA polymerase IV) HQ3359A 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110667189 Nonpathogen - hypothetical protein HQ1219A 5 None None None 110668471 Common msc probable mechanosensitive ion channel HQ2562A 14 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110668515 Common arsD arsenical resistance operon trans-acting repressor ArsD (transcriptional regulator) HQ2608A 31 None None None 110668828 Common eno phosphopyruvate hydratase HQ2935A 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 110667906 Common trkA Trk-type potassium transport system, NAD-binding subunit HQ1956A 117 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110667484 Nonpathogen - hypothetical protein HQ1524A 4 None None None 110669183 Common livJ ABC-type branched-chain amino acid transport systems, substrate-binding protein HQ3303A 89 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110667202 Common - rhomboid family protein/GlpG-like protein HQ1233A 142 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110668053 Nonpathogen - hypothetical protein HQ2108A 1 None None None 110667800 Common proB glutamate 5-kinase HQ1845A 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 110668874 Common galE nucleoside-diphosphate-sugar epimerase (probable UDP-glucose 4-epimerase) HQ2985A 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110668292 Common tenA transcription regulator HQ2369A 77 COG0819 TenA, Putative transcription activator Transcription 110667634 Common phaB1 putative monovalent cation/H+ antiporter subunit B HQ1677A 63 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 110668046 Nonpathogen - hypothetical protein HQ2101A 1 None None None 110667269 Nonpathogen secG preprotein translocase subunit SecG HQ1302A 4 COG4023 SBH1, Preprotein translocase subunit Sec61beta Intracellular trafficking and secretion 110669066 Common livJ ABC-type branched-chain amino acid transport systems, substrate-binding protein HQ3182A 123 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110668184 Common - ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/molybdate) HQ2247A 47 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110669037 Common - homolog to thiosulfate sulfurtransferase HQ3152A 72 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110667869 Nonpathogen - hypothetical protein HQ1918A 1 None None None 110668412 Nonpathogen - hypothetical protein HQ2502A 12 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 110668481 Nonpathogen tif2b translation initiation factor aIF-2 beta subunit HQ2573A 26 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 110667607 Common - phosphoesterase homolog HQ1649A 50 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 110668898 Common guaD probable nucleoside deaminase (cytosine deaminase, guanine deaminase) HQ3010A 57 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110667379 Common nfo endonuclease IV HQ1417A 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 110669381 Common neuB sialic acid synthase (N-acetylneuraminate synthase) (N-acetylneuraminic acid synthase) (N-acetylneuraminate-9-phosphate synthase) (N-acetylneuraminic acid phosphate synthase) HQ3519A 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 110668428 Nonpathogen - probable TP rich cell surface protein similar to viral TPX HQ2519A 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 110669202 Common - hypothetical protein HQ3324A 16 COG4347 COG4347, Predicted membrane protein Function unknown 110668526 Common guaD probable nucleoside deaminase (cytosine deaminase, guanine deaminase) HQ2620A 84 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110668973 Nonpathogen - hypothetical protein HQ3087A 3 None None None 110669537 Nonpathogen - hypothetical protein HQ3687A 2 None None None 110667471 Common lysA diaminopimelate decarboxylase HQ1510A 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 110667391 Nonpathogen - hypothetical protein HQ1429A 4 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 110669472 Common cbiM1 ABC-type cobalt transport system, permease protein HQ3621A 89 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 110668706 Common livM ABC-type branched-chain amino acid transport system, permease protein II HQ2807A 142 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110667600 Common nuoI NADH dehydrogenase-like complex, subunit I HQ1641A 188 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 110667783 Common cbs CBS domain protein HQ1828A 25 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 110667056 Common kch kef-type K+ transport systems, predicted NAD-binding component HQ1080A 102 None None None 110667268 Common hisH imidazoleglycerol-phosphate synthase HQ1301A 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 110668010 Nonpathogen - hypothetical protein HQ2065A 1 None None None 110667741 Common bat bacterioopsin activator/sensor histidine kinase HQ1787A 74 None None None 110669457 Common cbp cell surface calcium-binding acidic-repeat protein HQ3601A 23 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110669244 Nonpathogen - transposase fragment HQ3369A 2 None None None 110668625 Common ushA 5'-nucleotidase; 2',3'-cyclic-nucleotide 2'-phosphodiesterase; UDP-sugar hydrolase HQ2723A 131 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110667975 Common nudF ADP-ribose pyrophosphatase HQ2028A 164 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110668426 Nonpathogen - hypothetical protein HQ2517A 34 COG1500 COG1500, Predicted exosome subunit Translation, ribosomal structure and biogenesis 110667503 Common pan2 proteasome-activating nucleotidase HQ1544A 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 110667446 Common dppB ABC-type dipeptide/oligopeptide/nickel transport system, permease protein I HQ1485A 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110669046 Common - hypothetical protein HQ3161A 100 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 110669030 Common tdk thymidylate kinase HQ3145A 236 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 110667029 Common pyrD dihydroorotate dehydrogenase 2 HQ1052A 217 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 110667102 Common hoxF NAD-reducing hydrogenase, alpha subunit HQ1128A 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 110667398 Nonpathogen hstA archaeal histone HQ1436A 4 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 110667720 Nonpathogen - hypothetical protein HQ1766A 2 None None None 110667207 Common cinA CinA-like domain protein HQ1238A 189 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 110668321 Nonpathogen nac nascent polypeptide-associated complex protein HQ2399A 30 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 110669069 Common livG ABC-type branched-chain amino acid transport systems, ATP-binding protein I HQ3185A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667494 Common korB 2-oxoglutarate ferredoxin oxidoreductase subunit beta HQ1535A 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 110668675 Common carA carbamoyl phosphate synthase small subunit HQ2774A 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 110667729 Nonpathogen gvpH gas-vesicle operon protein gvpH HQ1775A 1 None None None 110669149 Common cdc6_ cell division control protein cdc6 homolog HQ3268A 32 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 110668406 Nonpathogen - hypothetical protein HQ2496A 5 None None None 110667301 Common rpoE1 DNA-directed RNA polymerase subunit E' HQ1337A 39 COG1095 RPB7, DNA-directed RNA polymerase, subunit E' Transcription 110668949 Common - IS1341-type transposase HQ3062A 50 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110669224 Common speB agmatinase HQ3349A 125 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 110667118 Common nosY ABC-type copper transport system involved in multi-copper enzyme maturation, permease protein HQ1144A 31 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 110669093 Common pphA serine/threonine protein phosphatase HQ3209A 33 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 110667616 Nonpathogen - hypothetical protein HQ1659A 12 COG2835 COG2835, Uncharacterized conserved protein Function unknown 110667819 Nonpathogen - hypothetical protein HQ1865A 1 None None None 110669460 Nonpathogen - hypothetical protein HQ3604A 2 None None None 110668565 Common ligB DNA ligase (ATP) HQ2659A 105 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 110667815 Nonpathogen - predicted DNA binding protein, probable transcriptional regulator HQ1861A 10 COG3413 COG3413, Predicted DNA binding protein General function prediction only 110668635 Nonpathogen ctaA cytochrome-c-aa3 oxidase assembly factor CtaA HQ2733A 4 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 110669463 Nonpathogen - conserved hypothetical protein (nonfunctional,N-terminal part) HQ3607A 2 None None None 110668419 Common ribG hypothetical protein HQ2510A 204 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 110669281 Common - probable RNA methylase HQ3407A 34 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 110667970 Common mntH NRAMP family Mn2+/Fe2+ transporters HQ2023A 31 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 110669161 Common - hypothetical protein HQ3280A 9 None None None 110668588 Common graD sugar nucleotidyltransferase II (probable glucose-1-phosphate thymidylyltransferase) HQ2682A 236 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110667211 Nonpathogen secE preprotein translocase subunit SecE HQ1242A 13 COG2443 Sss1, Preprotein translocase subunit Sss1 Intracellular trafficking and secretion 110668781 Nonpathogen rps28e 30S ribosomal protein S28e HQ2884A 33 COG2053 RPS28A, Ribosomal protein S28E/S33 Translation, ribosomal structure and biogenesis 110668385 Common fumC fumarate hydratase HQ2471A 225 COG0114 FumC, Fumarase Energy production and conversion 110668616 Nonpathogen - probable peptidoglycan binding protein HQ2714A 4 None None None 110667276 Common dppB ABC-type dipeptide/oligopeptide/nickel transport system, permease protein I HQ1309A 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110668554 Common ndh NADH dehydrogenase HQ2648A 185 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 110668888 Common spoVR spore cortext formation protein homolog HQ3000A 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 110669109 Common - predicted transporter HQ3227A 134 COG2252 COG2252, Permeases General function prediction only 110668196 Nonpathogen - hypothetical protein HQ2260A 1 None None None 110667898 Nonpathogen - hypothetical protein HQ1948A 3 None None None 110668762 Nonpathogen - probable stress response protein HQ2864A 9 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110667518 Common - hypothetical protein HQ1559A 18 COG2322 COG2322, Predicted membrane protein Function unknown 110668143 Nonpathogen - conserved hypothetical protein (nonfunctional,C-terminal region) HQ2205A 3 None None None 110667516 Nonpathogen hcpF halocyanin hcpF HQ1557A 6 COG3794 PetE, Plastocyanin Energy production and conversion 110667127 Nonpathogen tfbA transcription initiation factor TFB HQ1153A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667342 Common - uracil-DNA glycosylase homolog HQ1380A 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 110667602 Nonpathogen nuoJ2 NADH dehydrogenase-like complex, subunit J2 HQ1644A 4 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 110668841 Common moaA molybdenum cofactor biosynthesis protein A HQ2948A 201 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110667402 Nonpathogen - hypothetical protein HQ1440A 1 None None None 110668569 Nonpathogen - hypothetical protein HQ2663A 18 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 110667757 Nonpathogen ocd probable ornithine cyclodeaminase HQ1803A 5 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110669358 Nonpathogen - conserved hypothetical protein (nonfunctional,N-terminal part) HQ3493A 1 None None None 110667649 Common hisK probable histidinol phosphatase HQ1692A 58 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 110668853 Nonpathogen - hypothetical protein HQ2960A 1 None None None 110668909 Common ilvD dihydroxy-acid dehydratase HQ3021A 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 110668947 Common - serine/threonine protein kinase related protein HQ3060A 15 COG1520 COG1520, FOG: WD40-like repeat Function unknown 110668393 Nonpathogen - hypothetical protein HQ2480A 1 None None None 110668212 Common - hypothetical protein HQ2279A 14 COG3403 COG3403, Uncharacterized conserved protein Function unknown 110669406 Nonpathogen - probable arylsulfatase A-like HQ3545A 1 COG3379 COG3379, Uncharacterized conserved protein Function unknown 110668652 Nonpathogen - probable response regulator / probable transcription regulator HQ2751A 4 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110667198 Common rnhA ribonuclease H I HQ1228A 37 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 110668133 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ2194A 207 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667939 Common ugpA ABC-type sugar/sn-glycerol-3-phosphate transport system, periplasmic protein HQ1991A 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110668016 Nonpathogen - hypothetical protein HQ2071A 1 None None None 110669288 Common achY S-adenosyl-L-homocysteine hydrolase HQ3414A 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 110669104 Nonpathogen grx probable glutaredoxin HQ3221A 6 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110667015 Nonpathogen - hypothetical protein HQ1038A 5 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 110667173 Nonpathogen - hypothetical protein HQ1201A 1 None None None 110668050 Nonpathogen - hypothetical protein HQ2105A 2 None None None 110666997 Nonpathogen - probable prepilin signal peptidase HQ1021A 11 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110668031 Common - hypothetical protein HQ2086A 7 None None None 110667991 Common cynT carbonic anhydrase HQ2046A 52 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 110668754 Nonpathogen - hypothetical protein HQ2856A 4 None None None 110669583 Nonpathogen - hypothetical protein HQ3735A 4 None None None 110667825 Nonpathogen - hypothetical protein HQ1871A 4 None None None 110667702 Nonpathogen - hypothetical protein HQ1748A 3 None None None 110668020 Common rad predicted ATPase invovled in DNA repair HQ2075A 33 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 110669579 Common cysA thiosulfate sulfurtransferase HQ3730A 139 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110667770 Common - probable glucose dehydrogenase, type B; probable L-sorbosone dehydrogenase HQ1816A 115 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 110667552 Nonpathogen - hypothetical protein HQ1593A 3 None None None 110668304 Common - beta,beta-carotene 15,15'-monooxygenase; beta-carotene dioxygenase 1 HQ2381A 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 110667576 Common livM ABC-type branched-chain amino acid transport system, permease protein II HQ1617A 159 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110668363 Nonpathogen - hypothetical protein HQ2447A 4 None None None 110667191 Common - hypothetical protein HQ1221A 38 COG1656 COG1656, Uncharacterized conserved protein Function unknown 110669176 Nonpathogen - hypothetical protein HQ3295A 1 None None None 110667083 Common truA tRNA pseudouridine synthase A HQ1108A 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 110667347 Common pheA prephenate dehydratase HQ1385A 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 110668252 Common epf mRNA cleavage and polyadenylation specificity factor homolog HQ2326A 72 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 110669048 Common nudF ADP-ribose pyrophosphatase; Mut/nudix family protein HQ3163A 94 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110667736 Common gvpA gas vesicle synthesis protein GvpA HQ1782A 22 None None None 110667111 Nonpathogen - hypothetical protein HQ1137A 4 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 110669129 Nonpathogen atpK H(+)-transporting two-sector ATPase, subunit K (A-type ATP synthase) HQ3248A 1 None None None 110667135 Nonpathogen blp bacterioopsin-linked protein blp HQ1161A 10 COG5637 COG5637, Predicted integral membrane protein Function unknown 110668895 Common - beta,beta-carotene 9',10'-dioxygenase 2 HQ3007A 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 110669369 Common graD sugar nucleotidyltransferase II (probable glucose-1-phosphate thymidylyltransferase) HQ3507A 238 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110669397 Nonpathogen - hypothetical protein HQ3536A 1 None None None 110667523 Common thrC threonine synthase HQ1564A 127 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 110669394 Common - hexosyltransferase; glycosyltransferase HQ3532A 206 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110668165 Nonpathogen - hypothetical protein HQ2227A 1 None None None 110667280 Common cat2 probable cationic amino acid transport protein HQ1313A 186 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 110667958 Nonpathogen bcp thioredoxin-dependent hydroperoxide peroxidase HQ2009A 4 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110669293 Common ftsY signal recognition particle receptor SRalpha HQ3419A 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 110668954 Common - hypothetical protein HQ3067A 22 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110668370 Common psmA2 proteasome subunit alpha HQ2454A 39 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 110669123 Common atpD V-type ATP synthase subunit D HQ3242A 36 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 110667227 Nonpathogen - hypothetical protein HQ1258A 1 None None None 110667683 Common - probable glycosyl transferase HQ1728A 10 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110668445 Common - IS1341-type transposase HQ2536A 57 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 110669432 Nonpathogen - hypothetical protein HQ3575A 4 None None None 110667534 Nonpathogen - hypothetical protein HQ1575A 4 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110668344 Nonpathogen - hypothetical protein HQ2422A 5 None None None 110668833 Nonpathogen rpl18R 50S ribosomal protein L18e HQ2940A 34 COG1727 RPL18A, Ribosomal protein L18E Translation, ribosomal structure and biogenesis 110667547 Nonpathogen - hypothetical protein HQ1588A 1 None None None 110669490 Common - phosphoesterase,metallo-phosphoesterase-calcineu rin-like HQ3640A 56 COG0622 COG0622, Predicted phosphoesterase General function prediction only 110668553 Common udp uridine phosphorylase HQ2647A 102 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 110667609 Nonpathogen - hypothetical protein HQ1651A 4 None None None 110668715 Nonpathogen - hypothetical protein HQ2816A 1 None None None 110669444 Nonpathogen abrB transcription regulator HQ3588A 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 110668503 Common phnE ABC-type phosphate/phosphonate transport system,permease protein HQ2596A 84 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 110667968 Common - beta,beta-carotene 9',10'-dioxygenase 2 HQ2020A 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 110668918 Common - hypothetical protein HQ3030A 22 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 110669053 Common trpF phosphoribosylanthranilate isomerase HQ3168A 138 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 110668934 Nonpathogen - hypothetical protein HQ3045A 14 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 110669335 Nonpathogen - nifU protein C-terminal domain homolog HQ3465A 6 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 110667926 Common tauC ABC-type nitrate/sulfonate/bicarbonate transport system, permease protein HQ1977A 56 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110668544 Nonpathogen - hypothetical protein HQ2638A 31 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 110667050 Common pepB aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) HQ1074A 65 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110669111 Common pyrE orotate phosphoribosyltransferase HQ3229A 92 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 110667901 Common trkA Trk-type potassium transport system, NAD-binding subunit HQ1951A 59 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110668829 Nonpathogen rpoK DNA-directed RNA polymerase subunit K HQ2936A 29 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 110666981 Common lysC aspartate kinase HQ1005A 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 110669005 Common - predicted NAD/FAD-dependent oxidoreductase HQ3119A 30 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 110667430 Common pstA ABC-type phosphate transport system, permease protein I HQ1469A 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110667213 Nonpathogen - hypothetical protein HQ1244A 28 COG1650 COG1650, Uncharacterized protein conserved in archaea Function unknown 110668177 Nonpathogen - hypothetical protein HQ2239A 2 None None None 110668641 Common cmk cytidylate kinase HQ2740A 37 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 110667767 Nonpathogen - conserved hypothetical protein (probable surface protein) HQ1813A 20 None None None 110668648 Common - hypothetical protein HQ2747A 26 COG3199 COG3199, Uncharacterized conserved protein Function unknown 110669270 Common rpoB2 DNA-directed RNA polymerase subunit beta'' HQ3396A 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 110667354 Common - homolog of lysine biosynthesis regulator/ribosomal protein S6 modification enzyme (glutaminyl transferase) HQ1392A 109 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 110667168 Nonpathogen gp2 glycoprotein gp2 HQ1195A 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 110667880 Common msrB peptide methionine sulfoxide reductase (R-form specific) HQ1930A 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110669277 Common elaC Ribonuclease Z (RNase Z) (tRNA 3 endonuclease) HQ3403A 145 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 110667352 Common - hypothetical protein HQ1390A 37 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 110668268 Nonpathogen - major facilitator superfamily transporter HQ2342A 5 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110667078 Nonpathogen - hypothetical protein HQ1103A 12 COG0392 COG0392, Predicted integral membrane protein Function unknown 110667885 Nonpathogen - hypothetical protein HQ1935A 1 None None None 110669171 Nonpathogen - hypothetical protein HQ3290A 1 None None None 110669227 Nonpathogen tyrA prephenate dehydrogenase HQ3352A 7 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 110667731 Nonpathogen gvpF gas-vesicle operon protein gvpF HQ1777A 10 None None None 110667875 Nonpathogen - IS1341-type transposase (nonfunctional,N-terminal part) HQ1924E 1 None None None 110668735 Common rps3p 30S ribosomal protein S3P HQ2836A 247 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 110668704 Common livF ABC-type branched-chain amino acid transport systems, ATP-binding protein I HQ2805A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667248 Common truD tRNA pseudouridine synthase D HQ1281A 82 COG0585 COG0585, Uncharacterized conserved protein Function unknown 110668142 Nonpathogen - conserved hypothetical protein (nonfunctional,N-terminal region) HQ2204A 3 None None None 110668473 Nonpathogen tfbA transcription initiation factor TFB HQ2564A 4 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 110667451 Nonpathogen - hypothetical protein HQ1490A 9 None None None 110667438 Common dppF ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein II HQ1477A 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110668372 Common thyA thymidylate synthase HQ2456A 140 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 110668911 Nonpathogen - hypothetical protein HQ3023A 2 COG4742 COG4742, Predicted transcriptional regulator Transcription 110667618 Common purNH phosphoribosylglycinamide formyltransferase/ phosphoribosylaminoimidazolecarboxamide formyltransferase HQ1661A 221 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 110668743 Nonpathogen - hypothetical protein HQ2844A 4 None None None 110668334 Common rspA molecular chaperone P45 HQ2412A 119 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110667064 Nonpathogen - hypothetical protein HQ1088A 5 COG3355 COG3355, Predicted transcriptional regulator Transcription 110668284 Nonpathogen - conserved rps operon protein HQ2359A 2 None None None 110667539 Nonpathogen - hypothetical protein HQ1580A 22 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 110668705 Common livG ABC-type branched-chain amino acid transport systems, ATP-binding protein II HQ2806A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110667746 Common - probable S-adenosylmethionine-dependent methyltransferase HQ1792A 13 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110667157 Nonpathogen - hypothetical protein HQ1184A 4 None None None 110669379 Common gpmB probable fructose-2,6-bisphosphatase; probable phosphoglyceromutase,type 2 HQ3517A 157 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110668380 Nonpathogen - hypothetical protein HQ2464A 27 COG1634 COG1634, Uncharacterized Rossmann fold enzyme General function prediction only