Burkholderia cenocepacia AU 1054 chromosome 1, complete sequence NC_008060 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 107024125 Common - hypothetical protein Bcen_2580 134 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 107023235 Common - nicotinic acid mononucleotide adenylyltransferase Bcen_1685 164 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 107023567 Common - branched-chain amino acid aminotransferase Bcen_2020 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 107024451 Common gcvT glycine cleavage system aminomethyltransferase T Bcen_2909 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 107023764 Common - inner-membrane translocator Bcen_2217 106 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 107022504 Common - transcriptional regulator, RpiR family Bcen_0949 72 COG1737 RpiR, Transcriptional regulators Transcription 107024088 Common - GCN5-related N-acetyltransferase Bcen_2543 94 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 107022763 Pathogen - hypothetical protein Bcen_1210 1 None None None 107022309 Common - extracellular solute-binding protein, family 1 Bcen_0753 116 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 107023092 Common - hypothetical protein Bcen_1541 15 None None None 107022663 Common - hypothetical protein Bcen_1110 99 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 107023349 Common nadE NAD synthetase Bcen_1800 214 COG0171 NadE, NAD synthase Coenzyme metabolism 107023728 Common - hypothetical protein Bcen_2181 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 107023208 Common - RDD domain protein Bcen_1658 33 COG1714 COG1714, Predicted membrane protein/domain Function unknown 107021935 Common groES co-chaperonin GroES Bcen_0377 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 107023874 Pathogen - hypothetical protein Bcen_2327 1 None None None 107022282 Common - NAD-dependent epimerase/dehydratase Bcen_0726 58 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 107023174 Common - hypothetical protein Bcen_1623 16 None None None 107022891 Pathogen - hypothetical protein Bcen_1339 1 None None None 107023708 Common - 3-methyladenine DNA glycosylase Bcen_2161 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 107021848 Common - glycosyl transferase, group 1 Bcen_0290 59 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107023904 Common - transcriptional regulator, LacI family Bcen_2358 126 COG1609 PurR, Transcriptional regulators Transcription 107022123 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Bcen_0566 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 107023183 Common - NADH-quinone oxidoreductase, F subunit Bcen_1632 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 107024424 Pathogen - hypothetical protein Bcen_2882 1 None None None 107022266 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Bcen_0710 167 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 107022971 Common - hypothetical protein Bcen_1419 21 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 107024037 Common - protein of unknown function DUF344 Bcen_2492 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 107021954 Common - glycosyl transferase, family 2 Bcen_0396 161 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107024217 Common - membrane protein Bcen_2673 33 COG3671 COG3671, Predicted membrane protein Function unknown 107022496 Common - PfkB Bcen_0941 111 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 107021838 Common - major facilitator superfamily MFS_1 Bcen_0278 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107024005 Pathogen - hypothetical protein Bcen_2460 1 None None None 107022659 Common - transcriptional regulator, HxlR family Bcen_1106 134 COG1733 COG1733, Predicted transcriptional regulators Transcription 107022714 Common - Amino acid adenylation Bcen_1161 196 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 107022388 Common - MATE efflux family protein Bcen_0833 69 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 107021821 Common hrcA heat-inducible transcription repressor Bcen_0261 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 107023758 Common - N-acetylglucosamine-6-phosphate deacetylase Bcen_2211 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 107024113 Common apaG ApaG Bcen_2568 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 107023770 Common - electron transport protein SCO1/SenC Bcen_2223 107 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 107022940 Common - response regulator receiver protein Bcen_1388 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 107023735 Common - ribose-phosphate pyrophosphokinase Bcen_2188 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 107024107 Common - Phenylacetic acid degradation protein paaN2 Bcen_2562 191 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107024046 Common - Sel1-like repeat Bcen_2501 102 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 107021736 Common - transcriptional regulator, RpiR family Bcen_0176 151 COG1737 RpiR, Transcriptional regulators Transcription 107024260 Common - Type IV pilus secretin PilQ Bcen_2716 141 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 107023544 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_1997 118 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107022898 Common - ATP dependent DNA ligase Bcen_1346 92 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 107022319 Common - Transketolase, central region Bcen_0763 167 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 107022321 Common - dihydrolipoamide dehydrogenase Bcen_0765 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 107023754 Common - Phosphotransferase system, N-acetylglucosamine-specific IIBC component Bcen_2207 51 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 107024295 Common - 50S ribosomal protein L29 Bcen_2751 120 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 107023434 Common - inner-membrane translocator Bcen_1885 161 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 107023899 Common - transcriptional regulator, LysR family Bcen_2353 153 COG0583 LysR, Transcriptional regulator Transcription 107022854 Common - Endoribonuclease L-PSP Bcen_1302 149 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 107023411 Common - phosphoadenosine phosphosulfate reductase Bcen_1862 158 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 107022809 Common - inner-membrane translocator Bcen_1257 102 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 107024466 Common - transcriptional regulator, LysR family Bcen_2924 181 COG0583 LysR, Transcriptional regulator Transcription 107023506 Common - pyridoxamine 5'-phosphate oxidase Bcen_1957 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 107022291 Common - exodeoxyribonuclease V, beta subunit Bcen_0735 198 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 107021802 Common - catalase/peroxidase HPI Bcen_0242 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 107022728 Common - TonB-dependent siderophore receptor Bcen_1175 118 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 107023169 Common - MaoC-like dehydratase Bcen_1618 78 COG2030 MaoC, Acyl dehydratase Lipid metabolism 107021909 Common - hypothetical protein Bcen_0351 7 COG4460 COG4460, Uncharacterized protein conserved in bacteria Function unknown 107022660 Common - Phenylacetic acid degradation-related protein Bcen_1107 50 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 162218047 Common rplN 50S ribosomal protein L14 Bcen_2749 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 107023356 Common - 3-ketoacyl-(acyl-carrier-protein) reductase Bcen_1807 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023290 Common - Phenazine biosynthesis PhzC/PhzF protein Bcen_1741 115 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 107023288 Common - aminotransferase, class I and II Bcen_1739 224 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 107024395 Common - response regulator receiver protein Bcen_2852 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 107024030 Common metX homoserine O-acetyltransferase Bcen_2485 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 107023197 Common - sulphate transporter Bcen_1647 127 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 107022231 Common - membrane protein Bcen_0675 31 COG3336 COG3336, Predicted membrane protein Function unknown 107024494 Common - F0F1 ATP synthase subunit delta Bcen_2952 174 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 107022705 Common - extracytoplasmic-function sigma-70 factor PvdS Bcen_1152 46 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107022611 Common - hypothetical protein Bcen_1058 16 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 107022969 Common - organic radical activating enzyme family protein Bcen_1417 14 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 107024102 Common - IstB-like ATP-binding protein Bcen_2557 108 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 107024345 Pathogen - hypothetical protein Bcen_2801 1 None None None 107022472 Common - protein of unknown function DUF1275 Bcen_0917 22 COG3619 COG3619, Predicted membrane protein Function unknown 107022686 Common - putative serine protein kinase, PrkA Bcen_1133 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 107022031 Common - Carboxylyase-related protein Bcen_0473 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 107023334 Common - ABC transporter related Bcen_1785 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 107021882 Common - hypothetical protein Bcen_0324 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 107021902 Common - aminotransferase, class V Bcen_0344 148 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 107024421 Pathogen - hypothetical protein Bcen_2879 1 None None None 107023879 Common - dihydrodipicolinate synthase Bcen_2332 230 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 107023694 Common - acyl-coenzyme A synthetases/AMP-(fatty) acid ligases-like Bcen_2147 112 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 107023008 Common - Phenazine biosynthesis PhzC/PhzF protein Bcen_1456 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 107023451 Common - lipoprotein signal peptidase Bcen_1902 206 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107023913 Common - UDP-N-acetylglucosamine pyrophosphorylase Bcen_2367 234 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 107024479 Common - transcriptional regulator, TetR family Bcen_2937 4 COG1309 AcrR, Transcriptional regulator Transcription 107023329 Common - ATPase-like Bcen_1780 32 COG3911 COG3911, Predicted ATPase General function prediction only 107023445 Common - fatty acid desaturase Bcen_1896 66 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 107023321 Pathogen - hypothetical protein Bcen_1772 1 None None None 107023881 Common - Prevent-host-death protein Bcen_2334 9 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 107024022 Common - ATP-dependent protease peptidase subunit Bcen_2477 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 107021767 Common ruvC Holliday junction resolvase Bcen_0207 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 107024499 Pathogen - hypothetical protein Bcen_2957 1 None None None 107021813 Common - globin Bcen_0253 134 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 107023590 Common - periplasmic sensor signal transduction histidine kinase Bcen_2043 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107021570 Common - Type II secretion system gspD Bcen_0008 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 107022525 Common - metallophosphoesterase Bcen_0970 32 COG1409 Icc, Predicted phosphohydrolases General function prediction only 107021948 Common - glucose-1-phosphate thymidylyltransferase Bcen_0390 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 107024075 Common - FAD dependent oxidoreductase Bcen_2530 114 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107024496 Common - F0F1 ATP synthase subunit C Bcen_2954 49 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 107022800 Pathogen - hypothetical protein Bcen_1247 1 None None None 107022174 Common - transcriptional regulator, AraC family Bcen_0618 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023481 Common xseA exodeoxyribonuclease VII large subunit Bcen_1932 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 107024309 Common - ATP-dependent DNA helicase RecQ Bcen_2765 219 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 107023465 Common - translation elongation factor G Bcen_1916 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 107023030 Common - Tetratricopeptide TPR_4 Bcen_1478 13 None None None 107023595 Common - Cupin 2, conserved barrel Bcen_2048 17 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 107021869 Common - hypothetical protein Bcen_0311 16 None None None 107023900 Common - porin, Gram-negative type Bcen_2354 26 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107022271 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_0715 21 None None None 107021944 Common - dihydroorotase Bcen_0386 197 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 107024203 Pathogen - hypothetical protein Bcen_2659 1 None None None 107023799 Common - nitrogen regulatory protein P-II Bcen_2252 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 107023836 Pathogen - hypothetical protein Bcen_2289 1 None None None 107024477 Common - extracellular solute-binding protein, family 3 Bcen_2935 157 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107022113 Pathogen - hypothetical protein Bcen_0556 1 None None None 107022911 Common - PRC-barrel Bcen_1359 37 COG1873 COG1873, Uncharacterized conserved protein Function unknown 107022021 Common - Nucleoside diphosphate pyrophosphatase Bcen_0463 50 None None None 107023576 Pathogen - hypothetical protein Bcen_2029 1 None None None 107022226 Common - methionine aminopeptidase, type I Bcen_0670 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 107021915 Common - hypothetical protein Bcen_0357 9 None None None 107022820 Common - binding-protein-dependent transport systems inner membrane component Bcen_1268 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 107022312 Common - Twin-arginine translocation pathway signal Bcen_0756 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022289 Common - protein of unknown function DUF893, YccS/YhfK Bcen_0733 56 COG1289 COG1289, Predicted membrane protein Function unknown 107023866 Common bioD dithiobiotin synthetase Bcen_2319 110 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 107023299 Common - hypothetical protein Bcen_1750 19 None None None 107023664 Common ubiB putative ubiquinone biosynthesis protein UbiB Bcen_2117 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 107023628 Common - tRNA-i(6)A37 modification enzyme MiaB Bcen_2081 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 107024363 Common - hypothetical protein Bcen_2819 3 None None None 107022595 Common - response regulator receiver protein Bcen_1042 48 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 107023151 Common - short-chain dehydrogenase/reductase SDR Bcen_1600 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022641 Common - tRNA-dihydrouridine synthase A Bcen_1088 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 107024353 Common - transcriptional regulator, LysR family Bcen_2809 154 COG0583 LysR, Transcriptional regulator Transcription 107023145 Common - NCS1 nucleoside transporter family Bcen_1594 76 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 107023255 Common - periplasmic protein Bcen_1705 10 COG3895 COG3895, Predicted periplasmic protein General function prediction only 107021596 Common fliQ flagellar biosynthesis protein FliQ Bcen_0034 89 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 107022613 Common - PfkB Bcen_1060 119 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 107023408 Common - uroporphyrin-III C-methyltransferase Bcen_1859 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 107021634 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Bcen_0073 203 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 107024234 Common - VacJ-like lipoprotein Bcen_2690 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 107023363 Common - phosphoenolpyruvate carboxylase Bcen_1814 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 107022158 Common - hypothetical protein Bcen_0601 60 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 107023109 Common - HAD-superfamily hydrolase subfamily IIB Bcen_1558 25 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 107024016 Common dapF diaminopimelate epimerase Bcen_2471 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 107022132 Common - hypothetical protein Bcen_0575 26 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 107021775 Common - NUDIX hydrolase Bcen_0215 49 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 107022713 Common - Amino acid adenylation Bcen_1160 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 107023676 Common - transcriptional regulator, RpiR family Bcen_2129 87 COG1737 RpiR, Transcriptional regulators Transcription 107021597 Common - flagellar biosynthetic protein FliR Bcen_0035 120 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 107022829 Pathogen - hypothetical protein Bcen_1277 1 None None None 107022648 Common - hypothetical protein Bcen_1095 2 None None None 107022745 Common - precorrin-2 C(20)-methyltransferase Bcen_1192 157 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 107023668 Common - protein of unknown function DUF971 Bcen_2121 50 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 107024164 Common - ImcF-related Bcen_2620 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 107024095 Common - hypothetical protein Bcen_2550 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 107024086 Common - YaeQ Bcen_2541 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 107022693 Common - peptidase M23B Bcen_1140 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 107023085 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Bcen_1534 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 107021605 Common - type III restriction enzyme, res subunit Bcen_0043 44 COG3587 COG3587, Restriction endonuclease Defense mechanisms 107023159 Common - membrane protein-like Bcen_1608 17 COG3235 COG3235, Predicted membrane protein Function unknown 107022147 Common rpsP 30S ribosomal protein S16 Bcen_0590 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 107023105 Common - Electron-transferring-flavoprotein dehydrogenase Bcen_1554 112 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 107023537 Common - periplasmic solute binding protein Bcen_1990 125 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 107024374 Common - Carboxymethylenebutenolidase Bcen_2831 110 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 107024047 Common - 2-dehydro-3-deoxyglucarate aldolase Bcen_2502 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 107023138 Common - cytochrome c biogenesis protein, transmembrane region Bcen_1587 103 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 107023602 Common - Mandelate racemase/muconate lactonizing enzyme-like Bcen_2055 125 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 107023087 Common - iron-containing alcohol dehydrogenase Bcen_1536 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 107022140 Common - electron transfer flavoprotein beta-subunit Bcen_0583 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 107023932 Common - hypothetical protein Bcen_2386 3 None None None 107023719 Common - KpsF/GutQ family protein Bcen_2172 197 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 107022674 Common - Thiosulphate-binding protein Bcen_1121 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 107024179 Common - protein of unknown function DUF879 Bcen_2635 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 107022739 Common - L-carnitine dehydratase/bile acid-inducible protein F Bcen_1186 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 107023016 Pathogen - hypothetical protein Bcen_1464 1 None None None 107023384 Common - cobyric acid synthase Bcen_1835 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 107024397 Common - flagellar motor protein MotA Bcen_2854 109 COG1291 MotA, Flagellar motor component Cell motility and secretion 107023020 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_1468 105 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107024239 Common thiG thiazole synthase Bcen_2695 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 107022208 Common - GTP-binding protein LepA Bcen_0652 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 107024143 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Bcen_2598 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 107022059 Common - Alkane-1 monooxygenase Bcen_0501 26 None None None 107021996 Common - undecaprenyl pyrophosphate phosphatase Bcen_0438 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 107022079 Common - DNA-directed RNA polymerase subunit omega Bcen_0521 113 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 107023519 Common - 2-dehydropantoate 2-reductase Bcen_1970 102 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 107023401 Common - cytochrome c, class I Bcen_1852 29 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 107024525 Common - NADH:flavin oxidoreductase/NADH oxidase Bcen_2983 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 107024215 Common tatA twin argininte translocase protein A Bcen_2671 90 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 107021899 Common - Cob(II)yrinic acid a,c-diamide reductase Bcen_0341 79 COG0778 NfnB, Nitroreductase Energy production and conversion 107022785 Common - GntR-like Bcen_1232 114 COG2186 FadR, Transcriptional regulators Transcription 107022765 Common - L-carnitine dehydratase/bile acid-inducible protein F Bcen_1212 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 107022461 Pathogen - hypothetical protein Bcen_0906 1 None None None 107023811 Common - acyl-CoA dehydrogenase-like Bcen_2264 153 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022543 Common - transcriptional regulator, LysR family Bcen_0988 118 COG0583 LysR, Transcriptional regulator Transcription 107023689 Common - peptidase M48, Ste24p Bcen_2142 55 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 107023992 Pathogen - hypothetical protein Bcen_2447 1 None None None 107022474 Common - phosphoesterase Bcen_0919 35 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 107022918 Common - hypothetical protein Bcen_1366 5 None None None 107023164 Common - putative aminotransferase Bcen_1613 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 107022772 Common - transcriptional regulator, MarR family Bcen_1219 110 COG1846 MarR, Transcriptional regulators Transcription 107023186 Common - NADH dehydrogenase subunit C Bcen_1635 171 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 107023213 Common - glucose-1-dehydrogenase Bcen_1663 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107024120 Common - adenylate cyclase Bcen_2575 52 COG3025 COG3025, Uncharacterized conserved protein Function unknown 107023639 Common - phospholipid/glycerol acyltransferase Bcen_2092 193 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 107022352 Common - phosphoribosyltransferase Bcen_0796 70 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 107021932 Common - putative transmembrane anti-sigma factor Bcen_0374 2 COG3794 PetE, Plastocyanin Energy production and conversion 107023488 Common rpsT 30S ribosomal protein S20 Bcen_1939 40 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 107022228 Common - transcriptional regulator, LysR family Bcen_0672 128 COG0583 LysR, Transcriptional regulator Transcription 107024223 Common - multiple antibiotic resistance (MarC)-related proteins Bcen_2679 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 107023745 Common - 2-isopropylmalate synthase Bcen_2198 208 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 107022469 Common - Amidohydrolase 3 Bcen_0914 98 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 107023739 Common - 4Fe-4S ferredoxin, iron-sulfur binding Bcen_2192 112 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 107022428 Common - Lytic transglycosylase, catalytic Bcen_0873 34 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 107022001 Pathogen - hypothetical protein Bcen_0443 1 None None None 107024365 Common - beta-lactamase-like Bcen_2821 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 107024154 Common - protein of unknown function DUF1508 Bcen_2610 28 COG3422 COG3422, Uncharacterized conserved protein Function unknown 107023951 Common flgG flagellar basal body rod protein FlgG Bcen_2406 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 107021985 Common - ABC transporter related Bcen_0427 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107022171 Common - hypothetical protein Bcen_0615 2 None None None 107021788 Common - Paraquat-inducible protein A Bcen_0228 55 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 107023727 Common - HPr kinase/phosphorylase Bcen_2180 59 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 107022249 Common - YdjC-like protein Bcen_0693 54 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 107022875 Common - succinate dehydrogenase iron-sulfur subunit Bcen_1323 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 107024505 Common - ABC transporter related Bcen_2963 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107023510 Pathogen - hypothetical protein Bcen_1961 1 None None None 107023059 Common - glucose-methanol-choline oxidoreductase Bcen_1507 96 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 107022109 Common - formate dehydrogenase, alpha subunit Bcen_0552 214 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 107023023 Common - (2Fe-2S)-binding Bcen_1471 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 107023856 Common - extracellular solute-binding protein, family 5 Bcen_2309 211 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 107021925 Common - D-amino-acid dehydrogenase Bcen_0367 131 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107021832 Common - deoxynucleoside kinase Bcen_0272 42 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 107023306 Pathogen - hypothetical protein Bcen_1757 1 None None None 107022447 Common - CDP-alcohol phosphatidyltransferase Bcen_0892 30 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 107022475 Common - Di-haem cytochrome c peroxidase Bcen_0920 92 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 107022726 Common - cobalamin biosynthesis protein CbiG Bcen_1173 5 None None None 107022527 Common - membrane protein Bcen_0972 17 COG3308 COG3308, Predicted membrane protein Function unknown 107022460 Pathogen - hypothetical protein Bcen_0905 1 None None None 107022137 Common - ABC transporter related Bcen_0580 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 107023032 Common - transcriptional regulator, AraC family Bcen_1480 127 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107023433 Common - ABC transporter related Bcen_1884 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107023068 Common - porin, Gram-negative type Bcen_1516 28 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107023314 Pathogen - hypothetical protein Bcen_1765 1 None None None 107023962 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase Bcen_2417 183 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 107023037 Common - Amidohydrolase 3 Bcen_1485 97 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 107022615 Common - inner-membrane translocator Bcen_1062 136 COG4158 COG4158, Predicted ABC-type sugar transport system, permease component General function prediction only 107023229 Common mgsA methylglyoxal synthase Bcen_1679 85 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 107022776 Common - OsmC-like protein Bcen_1223 90 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 107023222 Common - two component transcriptional regulator, winged helix family Bcen_1672 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107021858 Common - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Bcen_0300 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 107022192 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Bcen_0636 205 COG0313 COG0313, Predicted methyltransferases General function prediction only 107022567 Common - transcriptional regulator, LysR family Bcen_1013 187 COG0583 LysR, Transcriptional regulator Transcription 107022041 Pathogen - hypothetical protein Bcen_0483 1 None None None 107023626 Common - major facilitator superfamily MFS_1 Bcen_2079 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023760 Common dnaE2 error-prone DNA polymerase Bcen_2213 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 107022927 Common - multi-sensor hybrid histidine kinase Bcen_1375 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107021612 Common - Alkylhydroperoxidase AhpD core Bcen_0050 79 COG2128 COG2128, Uncharacterized conserved protein Function unknown 107024304 Common rpsJ 30S ribosomal protein S10 Bcen_2760 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 107021864 Common - transcriptional regulator, AraC family Bcen_0306 74 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107021641 Common - Polypeptide-transport-associated, FtsQ-type Bcen_0080 80 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 107024177 Pathogen - 63 kDa protein Bcen_2633 1 None None None 107024384 Common - 3-demethylubiquinone-9 3-methyltransferase Bcen_2841 66 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 107023062 Common - (Acyl-carrier protein) phosphodiesterase Bcen_1510 97 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 107021617 Pathogen - hypothetical protein Bcen_0056 1 None None None 107023477 Common - protein of unknown function DUF962 Bcen_1928 26 COG4539 COG4539, Predicted membrane protein Function unknown 107021819 Common - DNA repair protein RecN Bcen_0259 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 162218049 Common slmA nucleoid occlusion protein Bcen_2484 53 COG1309 AcrR, Transcriptional regulator Transcription 107022415 Common - acyl-CoA dehydrogenase-like Bcen_0860 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022958 Common - ATPase AAA-2 Bcen_1406 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 107022510 Common - Peptidoglycan-binding LysM Bcen_0955 29 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 107021738 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Bcen_0178 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 107023136 Common - transcriptional regulator, LysR family Bcen_1585 152 COG0583 LysR, Transcriptional regulator Transcription 107024417 Common - TPR repeat Bcen_2875 109 COG0457 NrfG, FOG: TPR repeat General function prediction only 107022003 Common - hypothetical protein Bcen_0445 2 None None None 107024065 Common - Patatin Bcen_2520 5 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 107024057 Common fmt methionyl-tRNA formyltransferase Bcen_2512 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 107024331 Common - indolepyruvate ferredoxin oxidoreductase Bcen_2787 92 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 107022344 Common - hypothetical protein Bcen_0788 27 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 107022866 Common - transcriptional regulator, LysR family Bcen_1314 122 COG0583 LysR, Transcriptional regulator Transcription 107021874 Common - OmpA/MotB Bcen_0316 145 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 107023928 Common - extracellular solute-binding protein, family 1 Bcen_2382 132 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 107023733 Common lolB outer membrane lipoprotein LolB Bcen_2186 23 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 107024166 Common - OmpA/MotB Bcen_2622 167 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 107022896 Common - hypothetical protein Bcen_1344 15 None None None 107024249 Common - Glutamate synthase (ferredoxin) Bcen_2705 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 107022126 Common ihfB integration host factor subunit beta Bcen_0569 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 107021973 Common - Lipopolysaccharide heptosyltransferase I Bcen_0415 82 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107022685 Pathogen - hypothetical protein Bcen_1132 1 None None None 107021684 Common - Redoxin Bcen_0124 152 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 107022999 Common - hypothetical protein Bcen_1447 9 None None None 107021662 Common - gamma-glutamyl kinase Bcen_0102 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 107024319 Common - lipolytic enzyme, G-D-S-L Bcen_2775 16 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 107024325 Common - hypothetical protein Bcen_2781 4 None None None 107022185 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Bcen_0629 59 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 107022840 Common - protein of unknown function DUF1452 Bcen_1288 27 COG5478 COG5478, Predicted small integral membrane protein Function unknown 107024515 Common - glucose-methanol-choline oxidoreductase Bcen_2973 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 107024480 Common - acyl-CoA dehydrogenase-like Bcen_2938 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022233 Common - electron transport protein SCO1/SenC Bcen_0677 106 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 107023040 Common - protein of unknown function DUF1427 Bcen_1488 14 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 107022697 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_1144 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107023850 Common - 5-methyltetrahydrofolate--homocysteine methyltransferase Bcen_2303 167 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 107022219 Common - excinuclease ABC, C subunit Bcen_0663 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 107023986 Common - two component transcriptional regulator, LuxR family Bcen_2441 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 107022947 Pathogen - hypothetical protein Bcen_1395 1 None None None 107022847 Common - putative transcriptional regulator Bcen_1295 39 COG3636 COG3636, Predicted transcriptional regulator Transcription 107021851 Common - ABC-2 type transporter Bcen_0293 30 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 107021646 Common - hypothetical protein Bcen_0086 8 None None None 107022812 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1260 171 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 107023701 Common - 3-hydroxylacyl-(acyl carrier protein) dehydratase-like Bcen_2154 14 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 107022737 Common - NUDIX hydrolase Bcen_1184 23 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 107024449 Common - oxidoreductase-like Bcen_2907 125 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 107022054 Common - cell divisionFtsK/SpoIIIE Bcen_0496 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 107021798 Common tgt queuine tRNA-ribosyltransferase Bcen_0238 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 162218057 Common cysM cysteine synthase B Bcen_0576 226 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 107021659 Common rplU 50S ribosomal protein L21 Bcen_0099 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 107024410 Pathogen - hypothetical protein Bcen_2868 1 None None None 107024130 Common - Twin-arginine translocation pathway signal Bcen_2585 154 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 107024329 Common - 4-hydroxyphenylpyruvate dioxygenase Bcen_2785 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 107023766 Pathogen - hypothetical protein Bcen_2219 2 None None None 107022166 Common - thioesterase superfamily Bcen_0610 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 107023076 Common - binding-protein-dependent transport systems inner membrane component Bcen_1525 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 107022278 Common - Rh-like protein/ammonium transporter Bcen_0722 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 107023268 Common - cytochrome c, class I Bcen_1718 41 COG2863 COG2863, Cytochrome c553 Energy production and conversion 107023054 Common - secretion protein HlyD Bcen_1502 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 107023498 Common - methylated-DNA--protein-cysteine methyltransferase Bcen_1949 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 107024080 Pathogen - hypothetical protein Bcen_2535 1 None None None 107022811 Common - Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases-like Bcen_1259 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 107023332 Common - hypothetical protein Bcen_1783 2 None None None 107023605 Common - cytochrome c, class I Bcen_2058 76 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 107021704 Common - hypothetical protein Bcen_0144 7 None None None 107021666 Common - multiple antibiotic resistance (MarC)-related proteins Bcen_0106 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 107022378 Common - Phosphate transport system permease protein 1 Bcen_0822 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 107023742 Common - signal recognition particle-docking protein FtsY Bcen_2195 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 107022519 Common - secretion protein HlyD Bcen_0964 95 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 107022605 Pathogen - hypothetical protein Bcen_1052 1 None None None 107022253 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_0697 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 107022653 Common - hypothetical protein Bcen_1100 2 None None None 107024286 Common rpsE 30S ribosomal protein S5 Bcen_2742 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 107021585 Common - Drug resistance transporter EmrB/QacA subfamily Bcen_0023 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107024431 Common - N-6 DNA methylase Bcen_2889 30 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 107022457 Common - ATPases involved in chromosome partitioning-like Bcen_0902 4 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107022293 Common - diguanylate phosphodiesterase Bcen_0737 157 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 107023630 Common - hypothetical protein Bcen_2083 194 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 107024489 Common - acyl-CoA synthetase Bcen_2947 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107022204 Common - anti sigma-E protein, RseA Bcen_0648 5 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 107023286 Common - hypothetical protein Bcen_1737 19 None None None 107022884 Common - glycogen branching enzyme Bcen_1332 142 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 107022938 Common - short-chain dehydrogenase/reductase SDR Bcen_1386 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 107023354 Common - inorganic pyrophosphatase Bcen_1805 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 107023176 Common - NADH dehydrogenase subunit M Bcen_1625 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 107021952 Common - ABC-2 type transporter Bcen_0394 119 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 107023369 Pathogen - hypothetical protein Bcen_1820 2 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 107023219 Common - hypothetical protein Bcen_1669 24 None None None 107022535 Common - short chain dehydrogenase Bcen_0980 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023546 Common - secretion protein HlyD Bcen_1999 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 107022487 Common - inner-membrane translocator Bcen_0932 116 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 107023782 Common - Methyltransferase type 11 Bcen_2235 102 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 162218055 Common thrS threonyl-tRNA synthetase Bcen_0993 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107023752 Common - Cyd operon protein YbgT Bcen_2205 10 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 107023253 Common - glutamyl-Q tRNA(Asp) synthetase Bcen_1703 245 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 107021970 Common - glycosyl transferase, family 2 Bcen_0412 54 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107023532 Common - extracellular solute-binding protein, family 1 Bcen_1985 99 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107023557 Common - phospholipase/lecithinase/hemolysin-like Bcen_2010 27 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 107023462 Common - isocitrate dehydrogenase Bcen_1913 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 107022735 Common - hypothetical protein Bcen_1182 29 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 107023751 Common - cytochrome d ubiquinol oxidase, subunit II Bcen_2204 152 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 107023436 Pathogen - hypothetical protein Bcen_1887 1 None None None 107024382 Common flhA flagellar biosynthesis protein A Bcen_2839 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 107023897 Common - alpha/beta hydrolase fold Bcen_2350 91 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107021846 Common - glycosyl transferase, family 2 Bcen_0288 148 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107022942 Pathogen - hypothetical protein Bcen_1390 1 None None None 107021969 Common - glycosyl transferase, group 1 Bcen_0411 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107023271 Common - VWA containing CoxE-like Bcen_1721 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 107023789 Common - Rhodanese-like Bcen_2242 144 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 107021890 Common - glutathione-dependent formaldehyde-activating, GFA Bcen_0332 65 COG3791 COG3791, Uncharacterized conserved protein Function unknown 107021636 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Bcen_0075 206 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 107023623 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Bcen_2076 127 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 107024347 Common - ABC transporter related Bcen_2803 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 107022650 Pathogen - hypothetical protein Bcen_1097 1 None None None 107024185 Common - hypothetical protein Bcen_2641 10 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 107023167 Common - glutathione S-transferase-like Bcen_1616 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107022636 Common - binding-protein-dependent transport systems inner membrane component Bcen_1083 189 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 107024032 Common - major facilitator superfamily MFS_1 Bcen_2487 108 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 107023823 Common - hypothetical protein Bcen_2276 59 COG2921 COG2921, Uncharacterized conserved protein Function unknown 107023504 Common - thioredoxin Bcen_1955 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 107022587 Common - Polypeptide-transport-associated, ShlB-type Bcen_1034 52 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 107022887 Common - 4-alpha-glucanotransferase Bcen_1335 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 107022493 Common - Myo-inositol catabolism IolB region Bcen_0938 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 107023312 Common - hypothetical protein Bcen_1763 3 None None None 107023278 Common - hypothetical protein Bcen_1729 16 None None None 107022662 Common - major facilitator superfamily MFS_1 Bcen_1109 130 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022677 Common - Sulphate transport system permease protein 1 Bcen_1124 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 107022721 Common - hypothetical protein Bcen_1168 7 COG4861 COG4861, Uncharacterized protein conserved in bacteria Function unknown 107024508 Common - Extracellular ligand-binding receptor Bcen_2966 104 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107024464 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Bcen_2922 34 None None None 107023565 Common - branched-chain amino acid transport Bcen_2018 6 COG4392 COG4392, Predicted membrane protein Function unknown 107023528 Common - ABC transporter related Bcen_1981 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 107024436 Pathogen - hypothetical protein Bcen_2894 1 None None None 107022690 Common - extracellular solute-binding protein, family 3 Bcen_1137 184 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107022334 Common - transcriptional regulator, LysR family Bcen_0778 129 COG0583 LysR, Transcriptional regulator Transcription 107021725 Common - ureidoglycolate hydrolase Bcen_0165 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 107023195 Common - hypothetical protein Bcen_1644 9 None None None 107021841 Common mutL DNA mismatch repair protein Bcen_0281 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 107023185 Common - NADH dehydrogenase subunit D Bcen_1634 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 107023301 Common - phage integrase Bcen_1752 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 107024208 Common - cytochrome c1 Bcen_2664 55 COG2857 CYT1, Cytochrome c1 Energy production and conversion 107023844 Common - enoyl-CoA hydratase Bcen_2297 165 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107021937 Common - Phosphomethylpyrimidine kinase type-1 Bcen_0379 192 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 107023427 Common - NAD-dependent epimerase/dehydratase Bcen_1878 70 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107023786 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Bcen_2239 205 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 107022480 Common - protein of unknown function DUF1234 Bcen_0925 50 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 107022502 Common - Xylose isomerase-like TIM barrel Bcen_0947 65 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 107022988 Common - hypothetical protein Bcen_1436 6 None None None 107024501 Common - parB-like partition proteins Bcen_2959 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 107023790 Common - phosphoglycerate mutase 1 family Bcen_2243 160 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 107023245 Common - Lipid A export ATP-binding/permease protein MsbA Bcen_1695 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 107023080 Common - amino acid permease-associated region Bcen_1529 185 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 107022304 Common - major facilitator superfamily MFS_1 Bcen_0748 67 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023463 Common - Pseudouridine synthase, Rsu Bcen_1914 172 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 107024267 Common - putative sulfite oxidase subunit YedZ Bcen_2723 74 COG2717 COG2717, Predicted membrane protein Function unknown 107024044 Common - Peptidoglycan glycosyltransferase Bcen_2499 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 107024440 Pathogen - phage-related integrase Bcen_2898 2 None None None 107021607 Pathogen - hypothetical protein Bcen_0045 1 None None None 107022396 Pathogen - hypothetical protein Bcen_0841 1 None None None 107022657 Pathogen - hypothetical protein Bcen_1104 1 None None None 107021796 Common secD preprotein translocase subunit SecD Bcen_0236 196 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 107024513 Common - ABC transporter related Bcen_2971 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107024003 Common - aldehyde dehydrogenase Bcen_2458 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107023703 Pathogen - hypothetical protein Bcen_2156 1 None None None 107022986 Common - D-amino-acid dehydrogenase Bcen_1434 111 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107023100 Common - integral membrane protein Bcen_1549 21 COG5500 COG5500, Predicted integral membrane protein Function unknown 107024453 Common - glycine dehydrogenase Bcen_2911 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 107022597 Common - type II secretion system protein Bcen_1044 68 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 107024426 Common - hypothetical protein Bcen_2884 7 None None None 107022740 Common - citrate transporter Bcen_1187 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 107024115 Common - phosphoglycolate phosphatase Bcen_2570 207 COG0546 Gph, Predicted phosphatases General function prediction only 107022836 Pathogen - hypothetical protein Bcen_1284 1 None None None 107023996 Common fliG flagellar motor switch protein G Bcen_2451 123 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 107023458 Common - cold-shock DNA-binding domain protein Bcen_1909 180 COG1278 CspC, Cold shock proteins Transcription 107022310 Common - transcriptional regulator, LacI family Bcen_0754 127 COG1609 PurR, Transcriptional regulators Transcription 107023143 Common - Na+ dependent nucleoside transporter-like Bcen_1592 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 107021762 Common - Phosphoglycerate mutase Bcen_0202 113 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 107023238 Common - Maf-like protein Bcen_1688 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 107024100 Common gyrB DNA gyrase subunit B Bcen_2555 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 107022555 Common - transcriptional regulator, MerR family Bcen_1000 90 COG0789 SoxR, Predicted transcriptional regulators Transcription 107022545 Common - Endoribonuclease L-PSP Bcen_0990 96 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 107023717 Common - adenine phosphoribosyltransferase Bcen_2170 181 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 107023994 Common - flagellar hook-basal body complex protein (FliE) Bcen_2449 48 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 107022288 Common - amino acid permease-associated region Bcen_0732 163 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 107023293 Common - transmembrane pair Bcen_1744 41 COG4125 COG4125, Predicted membrane protein Function unknown 107022247 Common - glycosyl transferase, family 2 Bcen_0691 36 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 107023872 Common - Na+/H+ antiporter Bcen_2325 112 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 107022323 Pathogen - hypothetical protein Bcen_0767 1 None None None 107023115 Common - porin, Gram-negative type Bcen_1564 22 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107022865 Common - helix-turn-helix, Fis-type Bcen_1313 50 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 107022381 Common - PAS/PAC sensor signal transduction histidine kinase Bcen_0825 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 107023583 Common - Integral membrane protein TerC Bcen_2036 72 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 107021653 Common - Dephospho-CoA kinase Bcen_0093 201 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 107023662 Common - Putative regulatory protein, FmdB Bcen_2115 74 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 107023282 Common - G-T/U mismatch-specific DNA glycosylase-like Bcen_1733 40 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 107023578 Pathogen - glycosyl hydrolase, BNR repeat Bcen_2031 1 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 107022645 Common - Curculin-like (mannose-binding) lectin Bcen_1092 9 None None None 107024462 Common - hypothetical protein Bcen_2920 3 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 107023107 Common - transcriptional regulator, AraC family Bcen_1556 69 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107021781 Common - Helix-turn-helix, type 11 Bcen_0221 81 COG2378 COG2378, Predicted transcriptional regulator Transcription 107023289 Common - Endoribonuclease L-PSP Bcen_1740 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 107022852 Common - short chain dehydrogenase Bcen_1300 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107021701 Common - short-chain dehydrogenase/reductase SDR Bcen_0141 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023946 Common flgK flagellar hook-associated protein FlgK Bcen_2401 128 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 107024470 Common - Conserved TM helix Bcen_2928 21 None None None 107023493 Common - nucleotide-binding protein Bcen_1944 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 107024136 Pathogen - hypothetical protein Bcen_2591 1 None None None 107022018 Common - Chromate transporter Bcen_0460 106 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 107023599 Common - glutathione-dependent formaldehyde-activating, GFA Bcen_2052 58 COG3791 COG3791, Uncharacterized conserved protein Function unknown 107022827 Common - alkylphosphonate utilization operon protein PhnA Bcen_1275 106 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 107023539 Common - ABC-3 Bcen_1992 158 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 107023666 Common - import inner membrane translocase, subunit Tim44 Bcen_2119 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 107022752 Common - major facilitator superfamily MFS_1 Bcen_1199 72 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 107024472 Common - hypothetical protein Bcen_2930 2 None None None 107022761 Common - binding-protein-dependent transport systems inner membrane component Bcen_1208 204 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 107023969 Common - Allophanate hydrolase subunit 2 Bcen_2424 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 107022145 Common - hypothetical protein Bcen_0588 12 COG2237 COG2237, Predicted membrane protein Function unknown 107023397 Common - protein of unknown function DUF541 Bcen_1848 27 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 107023563 Common - pyruvate kinase Bcen_2016 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 107021643 Common - cell division protein FtsZ Bcen_0082 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 107023934 Common - protein of unknown function DUF799 Bcen_2389 24 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 107023153 Common - transcriptional regulator, AraC family Bcen_1602 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023263 Common - transcriptional regulator, TetR family Bcen_1713 103 COG1309 AcrR, Transcriptional regulator Transcription 107022268 Common - NAD-dependent epimerase/dehydratase Bcen_0712 33 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107021728 Common - dihydrodipicolinate reductase Bcen_0168 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 107023604 Common - cytochrome c, class I Bcen_2057 56 COG2863 COG2863, Cytochrome c553 Energy production and conversion 107024123 Common - peptidase M61 Bcen_2578 57 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 107023958 Common - putative anti-sigma-28 factor, FlgM Bcen_2413 3 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 107023656 Common - acyl-CoA dehydrogenase-like Bcen_2109 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022523 Common - transcriptional regulator, LysR family Bcen_0968 142 COG0583 LysR, Transcriptional regulator Transcription 107022702 Common - fimbrial protein Bcen_1149 10 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 107023071 Common - thiamine pyrophosphate enzyme-like TPP-binding Bcen_1519 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 107021884 Pathogen - hypothetical protein Bcen_0326 1 None None None 107023970 Common - hypothetical protein Bcen_2425 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 107022212 Common recO DNA repair protein RecO Bcen_0656 68 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 107021769 Common - Dihydrouridine synthase TIM-barrel protein nifR3 Bcen_0209 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 107021836 Common - hypothetical protein Bcen_0276 147 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 107023178 Common - NADH dehydrogenase subunit K Bcen_1627 84 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 107023045 Common - hypothetical protein Bcen_1493 60 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 107022670 Common - UspA Bcen_1117 63 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 107021677 Common - Adenosine kinase Bcen_0117 126 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 107024077 Common - Twin-arginine translocation pathway signal Bcen_2532 34 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 107023883 Common - major facilitator superfamily MFS_1 Bcen_2336 16 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107024254 Common - glycerol-3-phosphate transporter membrane protein Bcen_2710 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 107023841 Common - hypothetical protein Bcen_2294 9 None None None 107022807 Common - OsmC-like protein Bcen_1255 15 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 107021880 Common - short-chain dehydrogenase/reductase SDR Bcen_0322 208 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 107023484 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Bcen_1935 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 107022688 Common - hypothetical protein Bcen_1135 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 107021809 Common glcE glycolate oxidase FAD binding subunit Bcen_0249 134 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 107022665 Common - tRNA 2-selenouridine synthase Bcen_1112 65 COG2603 COG2603, Predicted ATPase General function prediction only 107021965 Common - glycosyl transferase, family 4 Bcen_0407 78 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 107023386 Common cobD cobalamin biosynthesis protein Bcen_1837 153 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 107024338 Common - hypothetical protein Bcen_2794 2 None None None 107024014 Common - putative plasmid maintenance system antidote protein, XRE family Bcen_2469 60 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 107023808 Pathogen - protein of unknown function DUF485 Bcen_2261 1 COG3162 COG3162, Predicted membrane protein Function unknown 107022711 Common - periplasmic binding protein Bcen_1158 75 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 107022681 Common - inner-membrane translocator Bcen_1128 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 107022085 Common - DNA polymerase III, epsilon subunit Bcen_0528 185 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 107023830 Common - ABC-type uncharacterized transport system auxiliary component-like Bcen_2283 16 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 107024039 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Bcen_2494 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 107023714 Common purU formyltetrahydrofolate deformylase Bcen_2167 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 107024390 Common - CheD, stimulates methylation of MCP proteins Bcen_2847 86 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 107022778 Common - hypothetical protein Bcen_1225 4 None None None 107024332 Common - malic enzyme Bcen_2788 217 COG0281 SfcA, Malic enzyme Energy production and conversion 107021867 Pathogen - conserved hypothetical 20.3 kDa protein Bcen_0309 4 None None None 107022350 Common - putative malonyl CoA-acylcarrier protein transacylase Bcen_0794 148 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 107023838 Common - pantothenate kinase Bcen_2291 129 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 107021904 Common - protein of unknown function DUF6, transmembrane Bcen_0346 105 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 107023442 Common - L-aspartate oxidase Bcen_1893 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 107023915 Common - protein of unknown function DUF1044 Bcen_2369 21 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 107022121 Common - chorismate mutase Bcen_0564 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 107023756 Common - Phosphoenolpyruvate-protein phosphotransferase Bcen_2209 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 107023797 Common - Glutamate--cysteine ligase GshA Bcen_2250 27 None None None 107023593 Common - transcriptional regulator, AraC family Bcen_2046 133 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107024201 Pathogen - hypothetical protein Bcen_2657 1 None None None 107023868 Common - CutC Bcen_2321 40 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 107021572 Common - General secretion pathway protein F Bcen_0010 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 107022913 Pathogen - hypothetical protein Bcen_1361 1 None None None 107022097 Pathogen - hypothetical protein Bcen_0540 1 None None None 107024498 Common - F0F1-type ATP synthase subunit I-like Bcen_2956 16 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 107022901 Pathogen - hypothetical protein Bcen_1349 1 None None None 107023327 Common - hypothetical protein Bcen_1778 2 None None None 107022931 Common - sigma54 specific transcriptional regulator, Fis family Bcen_1379 172 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107022621 Common - N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD Bcen_1068 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 107022273 Common - acriflavin resistance protein Bcen_0717 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 107022920 Common - short-chain dehydrogenase/reductase SDR Bcen_1368 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022259 Common - Arginine N-succinyltransferase Bcen_0703 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 107022600 Common - hypothetical protein Bcen_1047 4 None None None 107022755 Pathogen - hypothetical protein Bcen_1202 1 None None None 107024139 Common - transposase, IS4 Bcen_2594 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021960 Common - Methyltransferase FkbM Bcen_0402 166 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107024298 Common rplV 50S ribosomal protein L22 Bcen_2754 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 107022435 Common - hypothetical protein Bcen_0880 5 None None None 107024503 Common - methyltransferase GidB Bcen_2961 198 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 107022538 Common - 3-oxoacid CoA-transferase, subunit A Bcen_0983 99 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 107023654 Common - acetyl-CoA acetyltransferase Bcen_2107 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 107021927 Common - hypothetical protein Bcen_0369 39 None None None 107021719 Common - Alcohol dehydrogenase GroES-like Bcen_0159 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 107022638 Common - molybdenum-pterin binding domain Bcen_1085 48 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 107021590 Common - LrgB-like protein Bcen_0028 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 107023188 Common - NADH dehydrogenase subunit A Bcen_1637 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 107022214 Common acpS 4'-phosphopantetheinyl transferase Bcen_0658 128 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 107023964 Common - NAD-dependent epimerase/dehydratase Bcen_2419 146 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107022048 Common - binding-protein-dependent transport systems inner membrane component Bcen_0490 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 107023410 Common - sulfate adenylyltransferase subunit 2 Bcen_1861 127 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 107021731 Common leuS leucyl-tRNA synthetase Bcen_0171 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107024336 Common - N-acetyl-gamma-glutamyl-phosphate reductase Bcen_2792 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 107023360 Common - HemY-like Bcen_1811 38 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 107023417 Common - short-chain dehydrogenase/reductase SDR Bcen_1868 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107021599 Common - ABC transporter related Bcen_0037 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 107022194 Common - protein of unknown function DUF177 Bcen_0638 12 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 107023475 Common - Methyltransferase type 11 Bcen_1926 12 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 107021777 Common - NAD/NADP transhydrogenase alpha subunit-like Bcen_0217 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 107023440 Common rpmB 50S ribosomal protein L28 Bcen_1891 171 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 107024059 Common - DNA processing protein DprA, putative Bcen_2514 208 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 107022107 Common - monooxygenase, FAD-binding Bcen_0550 109 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 107023308 Common - phage transcriptional regulator, AlpA Bcen_1759 5 COG3311 AlpA, Predicted transcriptional regulator Transcription 107022197 Common - 3-oxoacyl-(acyl carrier protein) synthase III Bcen_0641 227 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 107023125 Common - natural resistance-associated macrophage protein Bcen_1574 101 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 107022540 Common - short chain dehydrogenase Bcen_0985 190 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107021578 Common - General secretion pathway protein K Bcen_0016 14 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 107023117 Common - dihydrodipicolinate synthetase Bcen_1566 213 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 107022186 Common moaA molybdenum cofactor biosynthesis protein A Bcen_0630 195 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 107023034 Common - transcriptional regulator, LysR family Bcen_1482 165 COG0583 LysR, Transcriptional regulator Transcription 107022929 Common - glycosyl transferase, family 2 Bcen_1377 13 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107022387 Pathogen - hypothetical protein Bcen_0832 1 None None None 107023224 Common - potassium-transporting ATPase, C subunit Bcen_1674 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 107024195 Common - hypothetical protein Bcen_2651 6 None None None 107022603 Common - hypothetical protein Bcen_1050 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 107022445 Common - phosphatidate cytidylyltransferase Bcen_0890 215 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 107024175 Common - ImpA-like Bcen_2631 37 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 107022099 Common - disulfide bond formation protein B Bcen_0542 24 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 107022202 Pathogen - hypothetical protein Bcen_0646 1 None None None 107024433 Common - hypothetical protein Bcen_2891 2 None None None 107022451 Common - diguanylate cyclase with GAF sensor Bcen_0896 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 107023517 Common - tryptophan 2,3-dioxygenase Bcen_1968 41 COG3483 TDO2, Tryptophan 2,3-dioxygenase (vermilion) Amino acid transport and metabolism 107024367 Common - transcriptional regulator, AsnC family Bcen_2823 166 COG1522 Lrp, Transcriptional regulators Transcription 107023691 Common - short chain dehydrogenase Bcen_2144 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022005 Common - phage integrase Bcen_0447 107 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 107023203 Common ilvH acetolactate synthase 3 regulatory subunit Bcen_1653 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 107022742 Common - transcriptional regulator, IclR family Bcen_1189 92 COG1414 IclR, Transcriptional regulator Transcription 107023740 Common coaD phosphopantetheine adenylyltransferase Bcen_2193 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 107022628 Common - arginyl-tRNA-protein transferase Bcen_1075 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 107023134 Common - protein of unknown function DUF336 Bcen_1583 54 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 107023977 Common - General substrate transporter Bcen_2432 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022992 Common - UspA Bcen_1440 107 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 107023449 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Bcen_1900 209 COG0196 RibF, FAD synthase Coenzyme metabolism 107023014 Common - transcriptional regulator, winged helix family Bcen_1462 109 COG3903 COG3903, Predicted ATPase General function prediction only 107024145 Common - amino acid permease-associated region Bcen_2601 146 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 107021619 Pathogen - hypothetical protein Bcen_0058 1 None None None 107022863 Common - Benzaldehyde dehydrogenase (NAD+) Bcen_1311 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107022206 Common - Peptidase S1C, Do Bcen_0650 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 107024020 Common - cobalamin synthesis protein, P47K Bcen_2475 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 107023381 Common - aspartate alpha-decarboxylase Bcen_1832 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 107022390 Common - AMP-dependent synthetase and ligase Bcen_0835 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 107022489 Common - ABC transporter related Bcen_0934 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107022463 Common - OsmC-like protein Bcen_0908 53 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 107022676 Common - Sulfate ABC transporter, permease protein CysW Bcen_1123 217 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 107024527 Common - transcriptional regulator, MarR family Bcen_2985 25 COG1846 MarR, Transcriptional regulators Transcription 107024520 Common phhB pterin-4-alpha-carbinolamine dehydratase Bcen_2978 89 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 107023103 Common - 3-hydroxybutyryl-CoA dehydrogenase Bcen_1552 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 107021660 Common rpmA 50S ribosomal protein L27 Bcen_0100 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 107021971 Common - membrane protein Bcen_0413 9 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 107023725 Common - sigma 54 modulation protein/ribosomal protein S30EA Bcen_2178 114 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 107023813 Common - transcriptional regulator, LysR family Bcen_2266 158 COG0583 LysR, Transcriptional regulator Transcription 107021678 Common - Redoxin Bcen_0118 98 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 107022062 Common - septum formation inhibitor Bcen_0504 103 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 107024141 Common - modification methylase, HemK family Bcen_2596 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 107024232 Common - hypothetical protein Bcen_2688 2 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 107022143 Common - transcriptional regulator, AsnC family Bcen_0586 141 COG1522 Lrp, Transcriptional regulators Transcription 107022960 Common - hypothetical protein Bcen_1408 7 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 107022798 Common - Taurine dioxygenase Bcen_1245 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 107021934 Common - hypothetical protein Bcen_0376 12 COG3427 COG3427, Uncharacterized conserved protein Function unknown 107024019 Common - PUA domain protein Bcen_2474 146 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 107022450 Pathogen - hypothetical protein Bcen_0895 1 None None None 107021746 Common - extracellular solute-binding protein, family 3 Bcen_0186 139 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107022404 Common - hypothetical protein Bcen_0849 3 None None None 107022787 Common - hypothetical protein Bcen_1234 2 None None None 107023737 Common - peptidyl-tRNA hydrolase Bcen_2190 215 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 107024153 Common - methyltransferase small Bcen_2609 77 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 107021922 Common - YheO-like Bcen_0364 44 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 107022570 Common - Pseudouridine synthase, Rsu Bcen_1016 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 107023637 Common glyS glycyl-tRNA synthetase subunit beta Bcen_2090 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 107021987 Common - inner-membrane translocator Bcen_0429 135 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 107023496 Common - AMP-dependent synthetase and ligase Bcen_1947 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107022843 Common - pyruvate decarboxylase Bcen_1291 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 107023025 Common - transcriptional regulator, LysR family Bcen_1473 178 COG0583 LysR, Transcriptional regulator Transcription 107022161 Pathogen - hypothetical protein Bcen_0604 1 None None None 107021811 Common - FAD linked oxidase-like Bcen_0251 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 107023607 Common - hypothetical protein Bcen_2060 2 None None None 107022168 Common - MATE efflux family protein Bcen_0612 147 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 107023936 Common - Twin-arginine translocation pathway signal Bcen_2391 29 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 107023636 Common glyQ glycyl-tRNA synthetase subunit alpha Bcen_2089 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 107023585 Common sucC succinyl-CoA synthetase subunit beta Bcen_2038 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 107024183 Common - Uncharacterised conserved protein UCP028301 Bcen_2639 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 107023089 Pathogen - hypothetical protein Bcen_1538 1 None None None 107022949 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Bcen_1397 229 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 107022056 Common - recombination factor protein RarA Bcen_0498 242 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 107023266 Common - protein of unknown function DUF6, transmembrane Bcen_1716 163 COG2962 RarD, Predicted permeases General function prediction only 107021712 Common - protein of unknown function DUF558 Bcen_0152 193 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 107022087 Pathogen - hypothetical protein Bcen_0530 1 None None None 107023078 Common - transposase, IS4 Bcen_1527 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 107024082 Pathogen - hypothetical protein Bcen_2537 1 None None None 107023096 Pathogen - hypothetical protein Bcen_1545 1 None None None 107024447 Common - UvrD/REP helicase Bcen_2905 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 107023858 Common - beta-lactamase-like Bcen_2311 75 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 107021664 Common - dinucleoside polyphosphate hydrolase Bcen_0104 114 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 107021758 Common - HesB/YadR/YfhF Bcen_0198 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 107024288 Common rplF 50S ribosomal protein L6 Bcen_2744 235 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 107023148 Common - allantoate amidohydrolase Bcen_1597 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 107021862 Common - glutamine amidotransferase, class-II Bcen_0304 60 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 107023377 Common - surface antigen (D15) Bcen_1828 120 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 107023523 Common - xylulokinase Bcen_1976 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 107024237 Common - ABC transporter related Bcen_2693 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 107022818 Common - extracellular solute-binding protein, family 5 Bcen_1266 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 107022410 Pathogen - hypothetical protein Bcen_0855 1 None None None 107023141 Common - Cytidine deaminase, homotetrameric Bcen_1590 114 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 107022569 Common - putative transcriptional regulator Bcen_1015 145 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 107023792 Common - UBA/THIF-type NAD/FAD binding fold Bcen_2245 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 107021877 Common - Biopolymer transport protein ExbD/TolR Bcen_0319 130 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 107022218 Common - hypothetical protein Bcen_0662 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 107022399 Common - hypothetical protein Bcen_0844 6 None None None 107023319 Common - hypothetical protein Bcen_1770 2 None None None 107022482 Common alaS alanyl-tRNA synthetase Bcen_0927 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107024306 Common - elongation factor G Bcen_2762 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 107023460 Pathogen - hypothetical protein Bcen_1911 1 None None None 107024270 Common - ResB-like Bcen_2726 49 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 107022849 Common - transcriptional regulator, TetR family Bcen_1297 66 COG1309 AcrR, Transcriptional regulator Transcription 107023206 Common - hypothetical protein Bcen_1656 5 None None None 107024455 Common - L-serine dehydratase 1 Bcen_2913 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 107024228 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Bcen_2684 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 107022533 Common - chorismate synthase Bcen_0978 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 107024222 Common hisH imidazole glycerol phosphate synthase subunit HisH Bcen_2678 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 107021671 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Bcen_0111 104 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 107023379 Common - chromosome segregation and condensation protein ScpA Bcen_1830 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 107023670 Common - FAD linked oxidase-like Bcen_2123 180 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 107021913 Common - TRAP-type uncharacterized transport system periplasmic component-like Bcen_0355 36 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 107024055 Common - heat shock protein HtpX Bcen_2510 193 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 107024311 Common rpoB DNA-directed RNA polymerase subunit beta Bcen_2767 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 107023559 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Bcen_2012 189 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 107022082 Common - porin, Gram-negative type Bcen_0524 33 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107022558 Common - hypothetical protein Bcen_1003 30 None None None 107022793 Common - luciferase-like Bcen_1240 78 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 107024054 Common - sun protein Bcen_2509 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 107023825 Common - Serine-type D-Ala-D-Ala carboxypeptidase Bcen_2278 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 107023698 Common - polysaccharide deacetylase Bcen_2151 108 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 107022882 Common - alpha amylase, catalytic region Bcen_1330 72 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 107022730 Common cobN cobaltochelatase Bcen_1177 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 107021998 Pathogen - hypothetical protein Bcen_0440 1 None None None 107023094 Common - deoxyribose-phosphate aldolase Bcen_1543 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 107023805 Common - periplasmic sensor signal transduction histidine kinase Bcen_2258 118 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 107023550 Common - carbon monoxide dehydrogenase subunit G Bcen_2003 3 COG3427 COG3427, Uncharacterized conserved protein Function unknown 107021623 Common - cytochrome B561 Bcen_0062 54 COG3038 CybB, Cytochrome B561 Energy production and conversion 107021981 Common ureA urease subunit gamma Bcen_0423 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 107022349 Common - Triphosphoribosyl-dephospho-CoA synthase Bcen_0793 46 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 107024411 Common - Tetratricopeptide TPR_2 Bcen_2869 89 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 107023006 Common - Endoribonuclease L-PSP Bcen_1454 74 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 107021698 Common - Twin-arginine translocation pathway signal Bcen_0138 33 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107022652 Common - protein of unknown function DUF1260 Bcen_1099 7 None None None 107022346 Common - malonate decarboxylase subunit beta Bcen_0790 186 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 107024327 Common - GCN5-related N-acetyltransferase Bcen_2783 18 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 107021856 Common - sulfatase Bcen_0298 33 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 107023984 Common - Ferredoxin--NADP(+) reductase Bcen_2439 95 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 107022501 Common - Myo-inositol 2-dehydrogenase Bcen_0946 123 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 107022889 Pathogen - hypothetical protein Bcen_1337 1 None None None 107024482 Common - hypothetical protein Bcen_2940 2 None None None 107022491 Common - short-chain dehydrogenase/reductase SDR Bcen_0936 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022997 Common - hypothetical protein Bcen_1445 3 None None None 107021686 Common - hypothetical protein Bcen_0126 25 None None None 107024069 Common - alpha/beta hydrolase fold Bcen_2524 120 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107022692 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1139 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107023828 Common - ferredoxin-like Bcen_2281 88 COG3411 COG3411, Ferredoxin Energy production and conversion 107022033 Common - aminotransferase Bcen_0475 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 107022573 Common nusA transcription elongation factor NusA Bcen_1019 221 COG0195 NusA, Transcription elongation factor Transcription 107023474 Common - diguanylate phosphodiesterase Bcen_1925 105 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 107023339 Common - hypothetical protein Bcen_1790 2 None None None 107023330 Common - Alpha,alpha-trehalose-phosphate synthase Bcen_1781 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 107021886 Common - protein of unknown function DUF883, ElaB Bcen_0328 23 COG4575 ElaB, Uncharacterized conserved protein Function unknown 107024263 Pathogen - hypothetical protein Bcen_2719 1 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 107022964 Pathogen - hypothetical protein Bcen_1412 1 None None None 107022216 Common - two component, sigma54 specific, transcriptional regulator, Fis family Bcen_0660 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107022507 Common - SirA-like Bcen_0952 120 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 107024439 Common - hypothetical protein Bcen_2897 3 None None None 107023353 Common - Excinuclease ABC, C subunit-like Bcen_1804 72 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 107023571 Common - alpha/beta hydrolase fold Bcen_2024 70 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 107022557 Pathogen - hypothetical protein Bcen_1002 1 None None None 107023469 Common - transcriptional regulator, GntR family Bcen_1920 126 COG2188 PhnF, Transcriptional regulators Transcription 107022934 Common - glycosyl transferase, family 2 Bcen_1382 71 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107022699 Common - Fimbrial protein Bcen_1146 20 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 107022804 Common - HipA-like Bcen_1252 81 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 107021749 Common - ABC transporter related Bcen_0189 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 107023163 Common - Protein of unknown function DUF132 Bcen_1612 16 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 107022229 Common - Pirin-like Bcen_0673 146 COG1741 COG1741, Pirin-related protein General function prediction only 107022683 Common - Ribokinase Bcen_1130 141 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 107023672 Common queF 7-cyano-7-deazaguanine reductase Bcen_2125 118 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 107021807 Common - Protein of unknown function UPF0001 Bcen_0247 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 107022521 Common - Fusaric acid resistance protein conserved region Bcen_0966 44 COG1289 COG1289, Predicted membrane protein Function unknown 107021648 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Bcen_0088 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 107023572 Common - hypothetical protein Bcen_2025 15 None None None 107023404 Common - leucyl aminopeptidase Bcen_1855 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 107022245 Common - alpha/beta hydrolase fold Bcen_0689 156 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107023242 Common - major facilitator superfamily MFS_1 Bcen_1692 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023325 Pathogen - hypothetical protein Bcen_1776 1 None None None 107024071 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_2526 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107021706 Common - phosphatidylglycerophosphatase A Bcen_0146 103 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 107022978 Common - molybdopterin biosynthesis MoaE Bcen_1426 148 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 107022591 Common - peptidase A24A, prepilin type IV Bcen_1038 13 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 107023383 Common - DoxX Bcen_1834 27 COG2259 COG2259, Predicted membrane protein Function unknown 107022517 Common - major facilitator superfamily MFS_1 Bcen_0962 104 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023749 Pathogen - hypothetical protein Bcen_2202 1 None None None 107022016 Common - L-carnitine dehydratase/bile acid-inducible protein F Bcen_0458 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 107024340 Common - transcriptional regulator, LysR family Bcen_2796 183 COG0583 LysR, Transcriptional regulator Transcription 107021574 Common - General secretion pathway protein G Bcen_0012 106 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 107022832 Common - two component transcriptional regulator, winged helix family Bcen_1280 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107021621 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Bcen_0060 112 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107021863 Common - Alkylhydroperoxidase AhpD core Bcen_0305 84 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 162218053 Common hemC porphobilinogen deaminase Bcen_1813 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 107023867 Common - biotin synthase Bcen_2320 176 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 107024106 Common - enoyl-CoA hydratase Bcen_2561 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107022862 Common - transcriptional regulator, AraC family Bcen_1310 54 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023180 Common - NADH dehydrogenase subunit I Bcen_1629 189 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 107021825 Pathogen - hypothetical protein Bcen_0265 1 None None None 107022442 Common - hypothetical protein Bcen_0887 29 None None None 107022222 Common - alpha/beta hydrolase fold Bcen_0666 66 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107023653 Common - enoyl-CoA hydratase Bcen_2106 174 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107021997 Common trmB tRNA (guanine-N(7))-methyltransferase Bcen_0439 177 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 107023804 Common - two component, sigma54 specific, transcriptional regulator, Fis family Bcen_2257 217 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107022180 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Bcen_0624 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 107023284 Common - heat shock protein 90 Bcen_1735 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 107023560 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Bcen_2013 227 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 107022417 Common - transcriptional regulator, PadR-like family Bcen_0862 36 COG1695 COG1695, Predicted transcriptional regulators Transcription 107024473 Common - Heavy metal translocating P-type ATPase Bcen_2931 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 107023736 Common - 50S ribosomal protein L25/general stress protein Ctc Bcen_2189 187 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 107023998 Common - Flagellar protein export ATPase FliI Bcen_2453 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 107022317 Common - hypothetical protein Bcen_0761 87 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 107023862 Common - hypothetical protein Bcen_2315 61 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 107021672 Common - ribonucleotide-diphosphate reductase subunit alpha Bcen_0112 227 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 107024349 Common - protein of unknown function DUF214 Bcen_2805 65 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 107024401 Common - histone-like nucleoid-structuring protein H-NS Bcen_2858 6 COG2916 Hns, DNA-binding protein H-NS General function prediction only 107022128 Common - hypothetical protein Bcen_0571 59 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 107022370 Common - protein of unknown function UPF0044 Bcen_0814 80 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 107023620 Common - hypothetical protein Bcen_2073 3 None None None 107024011 Pathogen - hypothetical protein Bcen_2466 1 None None None 107023839 Pathogen - hypothetical protein Bcen_2292 1 None None None 107023870 Pathogen - hypothetical protein Bcen_2323 2 None None None 107023832 Common - ABC transporter related Bcen_2285 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 107023113 Common - diguanylate phosphodiesterase Bcen_1562 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 107021764 Common - hypothetical protein Bcen_0204 25 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 107022596 Common - type II secretion system protein E Bcen_1043 156 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 107022339 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Bcen_0783 156 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 107024160 Pathogen - hypothetical protein Bcen_2616 1 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 107022644 Common - Curculin-like (mannose-binding) lectin Bcen_1091 14 None None None 107024427 Common - hypothetical protein Bcen_2885 7 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 107023937 Common - Glutathione reductase Bcen_2392 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 107023388 Common - periplasmic binding protein Bcen_1839 143 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 107024460 Pathogen - hypothetical protein Bcen_2918 3 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107024358 Common - transport-associated Bcen_2814 59 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 107022177 Common - nicotinate phosphoribosyltransferase Bcen_0621 81 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 107022656 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_1103 57 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 107024097 Common rpmH 50S ribosomal protein L34 Bcen_2552 197 None None None 107023555 Common - D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase Bcen_2008 105 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 107022750 Common - cobalt-precorrin-6x reductase Bcen_1197 45 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 107023967 Common - putative transcriptional regulator Bcen_2422 24 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 107023894 Common - protein of unknown function DUF1289 Bcen_2347 6 COG3313 COG3313, Predicted Fe-S protein General function prediction only 107021959 Common - NAD-dependent epimerase/dehydratase Bcen_0401 229 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107023711 Common - major facilitator superfamily MFS_1 Bcen_2164 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022285 Common - binding-protein-dependent transport systems inner membrane component Bcen_0729 186 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 107022838 Pathogen - hypothetical protein Bcen_1286 3 None None None 107022151 Common - NUDIX hydrolase Bcen_0594 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 107024420 Common - protein of unknown function DUF955 Bcen_2878 25 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 107023199 Pathogen - hypothetical protein Bcen_1649 1 None None None 107022230 Common - GCN5-related N-acetyltransferase Bcen_0674 79 COG2153 ElaA, Predicted acyltransferase General function prediction only 107022356 Common - General substrate transporter Bcen_0800 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022585 Common - hypothetical protein Bcen_1032 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021801 Common - transcriptional regulator, LysR family Bcen_0241 191 COG0583 LysR, Transcriptional regulator Transcription 107023270 Common - ATPase associated with various cellular activities, AAA_5 Bcen_1720 97 COG0714 COG0714, MoxR-like ATPases General function prediction only 107022976 Common - MoeA-like, domain I and II Bcen_1424 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 107021718 Common - short-chain dehydrogenase/reductase SDR Bcen_0158 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107021679 Common - Zinc finger/thioredoxin putative Bcen_0119 21 COG5373 COG5373, Predicted membrane protein Function unknown 107022306 Common - ABC transporter related Bcen_0750 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 107022700 Common - fimbrial biogenesis outer membrane usher protein Bcen_1147 28 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 107024292 Common rplX 50S ribosomal protein L24 Bcen_2748 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 107022709 Common - iron-hydroxamate transporter permease subunit Bcen_1156 186 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 107023712 Common - excinuclease ABC, A subunit Bcen_2165 234 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 107021563 Common - Enzymatic protein of unknown function Bcen_0001 68 COG2170 COG2170, Uncharacterized conserved protein Function unknown 107024310 Common - DNA-directed RNA polymerase subunit beta' Bcen_2766 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 107022144 Common - Radical SAM Bcen_0587 104 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 107022055 Common lolA outer-membrane lipoprotein carrier protein Bcen_0497 63 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 107023704 Common - Acetoacetyl-CoA reductase Bcen_2157 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023502 Common - protein of unknown function DUF6, transmembrane Bcen_1953 132 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 107023908 Common - hypothetical protein Bcen_2362 17 None None None 107022398 Common - Zinc finger, CHC2-type Bcen_0843 24 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 107024213 Common - Sec-independent protein translocase TatC Bcen_2669 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 107022946 Common - multiple antibiotic resistance (MarC)-related proteins Bcen_1394 122 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 107023724 Common - RNA polymerase factor sigma-54 Bcen_2177 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 107022438 Common - flavin reductase-like, FMN-binding Bcen_0883 54 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 107023643 Common ksgA dimethyladenosine transferase Bcen_2096 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 107023682 Common - Alpha/beta hydrolase fold-3 Bcen_2135 112 COG0657 Aes, Esterase/lipase Lipid metabolism 107021939 Pathogen - hypothetical protein Bcen_0381 1 None None None 107022290 Common - exodeoxyribonuclease V, gamma subunit Bcen_0734 63 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 107022962 Common - phospholipase D/Transphosphatidylase Bcen_1410 21 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 107022824 Common - protein of unknown function DUF1275 Bcen_1272 27 COG3619 COG3619, Predicted membrane protein Function unknown 107023170 Common - acyl-CoA dehydrogenase-like Bcen_1619 128 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022431 Pathogen - hypothetical protein Bcen_0876 1 None None None 107022393 Common - undecaprenyl pyrophosphate phosphatase Bcen_0838 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 107023731 Common - formamidopyrimidine-DNA glycosylase Bcen_2184 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 107024206 Common - ClpXP protease specificity-enhancing factor Bcen_2662 64 COG2969 SspB, Stringent starvation protein B General function prediction only 107023135 Common - short chain dehydrogenase Bcen_1584 224 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107022262 Common - succinylglutamate desuccinylase Bcen_0706 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 107023250 Common - glycosyl transferase, family 9 Bcen_1700 12 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107021739 Common - gluconate transporter Bcen_0179 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 107022336 Common - hypothetical protein Bcen_0780 34 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 107022025 Common - crcB protein Bcen_0467 37 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 107023621 Common - Xylose isomerase-like TIM barrel Bcen_2074 16 COG4130 COG4130, Predicted sugar epimerase Carbohydrate transport and metabolism 107023657 Common - transcriptional regulator, TetR family Bcen_2110 45 COG1309 AcrR, Transcriptional regulator Transcription 107021637 Common - Cell division protein FtsW Bcen_0076 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 107023425 Common - Pseudouridine synthase, Rsu Bcen_1876 116 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 107022894 Pathogen - hypothetical protein Bcen_1342 1 None None None 107022831 Pathogen - hypothetical protein Bcen_1279 1 None None None 107021834 Common - poly(A) polymerase Bcen_0274 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 107024027 Common - acetylglutamate kinase Bcen_2482 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 107022095 Common - protein of unknown function UPF0016 Bcen_0538 73 COG2119 COG2119, Predicted membrane protein Function unknown 107021976 Common - urease accessory protein UreG Bcen_0418 137 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 107022481 Common - L-carnitine dehydratase/bile acid-inducible protein F Bcen_0926 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 107022950 Common - formate dehydrogenase Bcen_1398 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 107022300 Common - oxidoreductase, molybdopterin binding Bcen_0744 126 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 107022903 Pathogen - hypothetical protein Bcen_1351 1 None None None 107021949 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Bcen_0391 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 107022733 Common - protein of unknown function DUF188 Bcen_1180 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 107023192 Common - polynucleotide phosphorylase/polyadenylase Bcen_1641 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 107024456 Common - SpoVT/AbrB-like protein Bcen_2914 7 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 107022922 Common - hypothetical protein Bcen_1370 12 None None None 107024519 Common phhA phenylalanine 4-monooxygenase Bcen_2977 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 107022252 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_0696 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 107024070 Common - ABC transporter related Bcen_2525 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 107022384 Pathogen - hypothetical protein Bcen_0828 1 None None None 107022756 Common - glutathione S-transferase-like Bcen_1203 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107022667 Pathogen - hypothetical protein Bcen_1114 1 None None None 107023358 Common - Excisionase/Xis, DNA-binding Bcen_1809 5 None None None 107024182 Common - protein of unknown function DUF877 Bcen_2638 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 107022944 Common - Alcohol dehydrogenase GroES-like Bcen_1392 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 107024404 Common - ATPase, BadF/BadG/BcrA/BcrD type Bcen_2861 37 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 107023903 Common - diguanylate cyclase/phosphodiesterase Bcen_2357 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 107023948 Common flgJ peptidoglycan hydrolase Bcen_2403 74 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 107022325 Common - porin, Gram-negative type Bcen_0769 26 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107024437 Common - Integrase, catalytic region Bcen_2895 40 None None None 107023774 Common - Surfeit locus 1 Bcen_2227 59 COG3346 COG3346, Uncharacterized conserved protein Function unknown 107022235 Common - Alpha,alpha-trehalose-phosphate synthase Bcen_0679 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 107021692 Common - peptidase S10, serine carboxypeptidase Bcen_0132 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 107023781 Common - integral membrane protein-like Bcen_2234 16 COG5488 COG5488, Integral membrane protein Function unknown 107021958 Common - GDP-mannose 4,6-dehydratase Bcen_0400 227 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 107024229 Common - BolA-like protein Bcen_2685 110 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 107023778 Pathogen - hypothetical protein Bcen_2231 1 None None None 107021967 Common - glycosyl transferase, family 4 Bcen_0409 118 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 107023189 Common secG preprotein translocase subunit SecG Bcen_1638 29 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 107023534 Common - PfkB Bcen_1987 148 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 107023509 Common - peptide methionine sulfoxide reductase Bcen_1960 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 107021793 Common - major facilitator superfamily MFS_1 Bcen_0233 168 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022536 Common - thioesterase superfamily Bcen_0981 62 COG0824 FcbC, Predicted thioesterase General function prediction only 107024469 Common - Ethanolamine permease Bcen_2927 184 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 107024243 Common - short-chain dehydrogenase/reductase SDR Bcen_2699 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023276 Common - hypothetical protein Bcen_1726 15 None None None 107023073 Common - transcriptional regulator, LacI family Bcen_1521 123 COG1609 PurR, Transcriptional regulators Transcription 107023160 Common - hypothetical protein Bcen_1609 2 None None None 107022870 Pathogen - hypothetical protein Bcen_1318 1 None None None 107023975 Common - binding-protein-dependent transport systems inner membrane component Bcen_2430 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 107022744 Common - precorrin-3B C17-methyltransferase Bcen_1191 117 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 107022995 Common - transcriptional regulator, AraC family Bcen_1443 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023612 Pathogen - hypothetical protein Bcen_2065 1 None None None 107024199 Common - hypothetical protein Bcen_2655 3 None None None 107022100 Common - amidase Bcen_0543 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 107024435 Common - hypothetical protein Bcen_2893 3 None None None 107023540 Common - Carboxylesterase Bcen_1993 91 COG0627 COG0627, Predicted esterase General function prediction only 107024300 Common rplB 50S ribosomal protein L2 Bcen_2756 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 107021980 Common ureB urease subunit beta Bcen_0422 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 107023885 Common - transcriptional regulator, LysR family Bcen_2338 140 COG0583 LysR, Transcriptional regulator Transcription 107022122 Common - Prephenate dehydrogenase Bcen_0565 148 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 107022514 Common valS valyl-tRNA synthetase Bcen_0959 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107022363 Common - Lytic transglycosylase, catalytic Bcen_0807 127 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 107024313 Common rplJ 50S ribosomal protein L10 Bcen_2769 212 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 107022678 Common - transcriptional regulator CysB-like protein Bcen_1125 190 COG0583 LysR, Transcriptional regulator Transcription 107024119 Common - Indole-3-glycerol-phosphate synthase Bcen_2574 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 107021828 Common - Chaperone DnaK Bcen_0268 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 107021680 Common prmA ribosomal protein L11 methyltransferase Bcen_0120 191 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 107022408 Pathogen - hypothetical protein Bcen_0853 1 None None None 107023921 Common - Heavy metal transport/detoxification protein Bcen_2375 25 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 107021650 Common - NUDIX hydrolase Bcen_0090 178 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 107021770 Common - hypothetical protein Bcen_0210 116 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 107023851 Common - hypothetical protein Bcen_2304 8 None None None 107022562 Pathogen - hypothetical protein Bcen_1008 1 None None None 107022788 Common - ABC nitrate/sulfonate/bicarbonate transporter, periplasmic ligand binding protein Bcen_1235 74 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 107023472 Common - hypothetical protein Bcen_1923 2 None None None 107023485 Common adk adenylate kinase Bcen_1936 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 107024084 Common - transcriptional regulator, AraC family Bcen_2539 200 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 107024414 Common - hypothetical protein Bcen_2872 4 None None None 107022671 Common - hypothetical protein Bcen_1118 14 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 107024162 Pathogen - hypothetical protein Bcen_2618 1 None None None 107023004 Common - transcriptional regulator, AraC family Bcen_1452 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107022844 Common - cytochrome c oxidase, subunit II Bcen_1292 159 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 107021870 Pathogen - hypothetical protein Bcen_0312 1 None None None 107024042 Common - rod shape-determining protein MreC Bcen_2497 122 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 107021744 Common - transcriptional regulator, LysR family Bcen_0184 169 COG0583 LysR, Transcriptional regulator Transcription 107023296 Common - DNA topoisomerase IV subunit A Bcen_1747 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 107023791 Common - carboxyl-terminal protease Bcen_2244 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 107023344 Common - ABC transporter related Bcen_1795 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 107022035 Common ribH riboflavin synthase subunit beta Bcen_0477 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 107023201 Common - phosphatidylserine decarboxylase Bcen_1651 93 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 107022008 Pathogen - hypothetical protein Bcen_0450 1 None None None 107024321 Common - phenylacetic acid degradation B Bcen_2777 39 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 107021715 Common - transketolase Bcen_0155 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 107024255 Common - binding-protein-dependent transport systems inner membrane component Bcen_2711 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 107022092 Common - fructose-1,6-bisphosphatase Bcen_0535 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 107023652 Common - formate dehydrogenase family accessory protein FdhD Bcen_2105 133 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 107022817 Common - GCN5-related N-acetyltransferase Bcen_1265 9 COG0456 RimI, Acetyltransferases General function prediction only 107023133 Common - hypothetical protein Bcen_1582 2 None None None 107021892 Common - hypothetical protein Bcen_0334 82 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 107022954 Common - phosphate-starvation-inducible E Bcen_1402 13 COG3223 COG3223, Predicted membrane protein Function unknown 107022412 Common - (2Fe-2S)-binding Bcen_0857 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 107024227 Common hisG ATP phosphoribosyltransferase catalytic subunit Bcen_2683 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 107024180 Common - protein of unknown function DUF1316 Bcen_2636 32 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 107023584 Common - succinyl-CoA synthetase subunit alpha Bcen_2037 207 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 107024002 Pathogen - hypothetical protein Bcen_2457 1 None None None 107022297 Pathogen - hypothetical protein Bcen_0741 1 None None None 107022610 Common - GCN5-related N-acetyltransferase Bcen_1057 79 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 107023394 Common - hypothetical protein Bcen_1845 2 None None None 107023098 Common - protein of unknown function DUF6, transmembrane Bcen_1547 88 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 107023264 Common - ferredoxin Bcen_1714 104 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 107023200 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Bcen_1650 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 107021592 Common fliM flagellar motor switch protein FliM Bcen_0030 114 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 107022419 Common - hypothetical protein Bcen_0864 22 None None None 107021581 Common - hypothetical protein Bcen_0019 10 None None None 107024062 Common - DNA topoisomerase III Bcen_2517 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 107024445 Common - transcriptional regulator, GntR family Bcen_2903 181 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 107023613 Common glpD glycerol-3-phosphate dehydrogenase Bcen_2066 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 107022375 Common - Periplasmic phosphate binding protein Bcen_0819 113 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 107023696 Common - hypothetical protein Bcen_2149 21 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 107021635 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Bcen_0074 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 107022163 Common - Thymidylate synthase Bcen_0606 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 107022791 Common - oxidoreductase, molybdopterin binding Bcen_1238 89 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 107024197 Common - phage protein Bcen_2653 18 None None None 107023939 Common - porin, Gram-negative type Bcen_2394 26 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107023123 Common - transcriptional regulator, TetR family Bcen_1572 74 COG1309 AcrR, Transcriptional regulator Transcription 107022531 Common - putative transcriptional regulator, XRE family Bcen_0976 121 COG0517 COG0517, FOG: CBS domain General function prediction only 107021879 Common - 4-hydroxybenzoyl-CoA thioesterase Bcen_0321 135 COG0824 FcbC, Predicted thioesterase General function prediction only 107024335 Common - flavodoxin/nitric oxide synthase Bcen_2791 95 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 107024009 Pathogen - hypothetical protein Bcen_2464 1 None None None 107024091 Common - diguanylate cyclase Bcen_2546 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 107022341 Common - transcriptional regulator, LysR family Bcen_0785 184 COG0583 LysR, Transcriptional regulator Transcription 107024052 Common - periplasmic sensor signal transduction histidine kinase Bcen_2507 216 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 107022084 Common - cold-shock DNA-binding domain protein Bcen_0527 178 COG1278 CspC, Cold shock proteins Transcription 107021978 Common ureE urease accessory protein UreE Bcen_0420 67 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 107021779 Common - transcriptional regulator, LysR family Bcen_0219 101 COG0583 LysR, Transcriptional regulator Transcription 107024370 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Bcen_2826 43 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 107021601 Common - periplasmic sensor signal transduction histidine kinase Bcen_0039 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107024485 Common - primosome assembly protein PriA Bcen_2943 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 107023618 Common - fatty acid desaturase Bcen_2071 26 COG3239 DesA, Fatty acid desaturase Lipid metabolism 107024521 Common - hypothetical protein Bcen_2979 9 None None None 107022626 Common - extracellular solute-binding protein, family 3 Bcen_1073 170 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107023721 Common - protein of unknown function DUF1239 Bcen_2174 20 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 107022579 Common - transcriptional regulator, MarR family Bcen_1026 20 COG1846 MarR, Transcriptional regulators Transcription 107022037 Common - hypothetical protein Bcen_0479 33 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 107022769 Common - transcriptional regulator, LysR family Bcen_1216 190 COG0583 LysR, Transcriptional regulator Transcription 107022796 Common - ABC transporter related Bcen_1243 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 107023422 Common - short chain dehydrogenase Bcen_1873 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107024266 Pathogen - putative lipoprotein Bcen_2722 1 None None None 107024150 Common - transcriptional regulator, TetR family Bcen_2606 52 COG1309 AcrR, Transcriptional regulator Transcription 107021588 Common - transcriptional regulator, LysR family Bcen_0026 190 COG0583 LysR, Transcriptional regulator Transcription 107022275 Common - secretion protein HlyD Bcen_0719 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 107024190 Common - RHS protein Bcen_2646 67 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 107023515 Common - putative cyclase Bcen_1966 76 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 107023769 Common - YCII-related Bcen_2222 39 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 107021911 Common - DSBA oxidoreductase Bcen_0353 31 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 107021921 Common - DSBA oxidoreductase Bcen_0363 80 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 107023026 Common - major facilitator superfamily MFS_1 Bcen_1474 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022073 Pathogen - hypothetical protein Bcen_0515 1 None None None 107023456 Common - ATP-dependent Clp protease ATP-binding subunit clpA Bcen_1907 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 107022465 Common - protein of unknown function DUF1427 Bcen_0910 16 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 107023066 Common - glycoside hydrolase, family 3-like Bcen_1514 170 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 107022914 Common - major facilitator superfamily MFS_1 Bcen_1362 161 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022619 Common - Ribonuclease R Bcen_1066 192 COG0557 VacB, Exoribonuclease R Transcription 107023524 Common - transcriptional regulator, DeoR family Bcen_1977 61 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 107024189 Pathogen - hypothetical protein Bcen_2645 1 None None None 107022497 Common - periplasmic binding protein/LacI transcriptional regulator Bcen_0942 95 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107024033 Common - peptidase M48, Ste24p Bcen_2488 100 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 107022069 Pathogen - hypothetical protein Bcen_0511 1 None None None 107022030 Common - Lysine exporter protein (LYSE/YGGA) Bcen_0472 9 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 107023685 Common - hypothetical protein Bcen_2138 94 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 107023244 Common - integral membrane protein-like Bcen_1694 15 COG5455 COG5455, Predicted integral membrane protein Function unknown 107022908 Pathogen - hypothetical protein Bcen_1356 1 None None None 107023878 Common - Thiosulphate-binding protein Bcen_2331 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 107023941 Common - Chromate transporter Bcen_2396 103 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 107024230 Common - ABC-2 type transporter Bcen_2686 166 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 107024147 Common - molecular chaperone-like Bcen_2603 228 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 107022050 Common - ABC transporter related Bcen_0492 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 107022966 Common - hypothetical protein Bcen_1414 12 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 107022382 Common - polyphosphate kinase Bcen_0826 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 107023011 Common - transcriptional regulator, LysR family Bcen_1459 142 COG0583 LysR, Transcriptional regulator Transcription 107022781 Common - hypothetical protein Bcen_1228 6 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 107023677 Common - amino acid aldolase or racemase-like Bcen_2130 57 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 107021991 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Bcen_0433 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 107022602 Common - sigma54 specific transcriptional regulator, Fis family Bcen_1049 164 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107024137 Common - two component transcriptional regulator, winged helix family Bcen_2592 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107024346 Common - secretion protein HlyD Bcen_2802 149 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 107024235 Common - Mammalian cell entry related Bcen_2691 98 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 107023002 Common - alpha/beta hydrolase fold Bcen_1450 137 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107021989 Common - Twin-arginine translocation pathway signal Bcen_0431 101 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107023248 Common - O-antigen polymerase Bcen_1698 15 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 107024281 Common rpmJ 50S ribosomal protein L36 Bcen_2737 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 107024211 Common - protein of unknown function DUF34 Bcen_2667 84 COG0327 COG0327, Uncharacterized conserved protein Function unknown 107023254 Common - DEAD/DEAH box helicase-like Bcen_1704 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 107022858 Common - Rieske (2Fe-2S) region Bcen_1306 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 107024246 Common - 2',5' RNA ligase Bcen_2702 5 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 107022423 Common - periplasmic binding protein Bcen_0868 74 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 107021784 Common - putative RNA methylase Bcen_0224 130 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 107022425 Common - periplasmic sensor signal transduction histidine kinase Bcen_0870 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107024116 Common - anthranilate synthase component I Bcen_2571 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 107022046 Common - glucose-6-phosphate 1-dehydrogenase Bcen_0488 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 107024360 Common - protein of unknown function UPF0102 Bcen_2816 101 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 107024491 Common - F0F1 ATP synthase subunit beta Bcen_2949 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 107023055 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_1503 117 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107022932 Common - glycosyl transferase, group 1 Bcen_1380 32 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107023816 Common - binding-protein-dependent transport systems inner membrane component Bcen_2269 185 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 107022633 Common - enoyl-CoA hydratase Bcen_1080 120 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107023467 Pathogen - hypothetical protein Bcen_1918 1 COG4907 COG4907, Predicted membrane protein Function unknown 107023049 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1497 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107023303 Common - inner membrane protein Bcen_1754 49 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 107022118 Common - DNA gyrase subunit A Bcen_0561 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 107021723 Common - C4-dicarboxylate transporter DctA Bcen_0163 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 107021837 Common - phosphoribosylaminoimidazole synthetase Bcen_0277 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 107022078 Common gmk guanylate kinase Bcen_0520 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 107022478 Common - glutaminyl-tRNA synthetase Bcen_0923 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 107024388 Common - response regulator receiver protein Bcen_2845 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107024173 Pathogen - hypothetical protein Bcen_2629 3 None None None 107021697 Common - short chain dehydrogenase Bcen_0137 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022199 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Bcen_0643 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022479 Pathogen - hypothetical protein Bcen_0924 1 None None None 107021569 Common - Lytic transglycosylase, catalytic Bcen_0007 35 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 107021860 Common - GCN5-related N-acetyltransferase Bcen_0302 2 COG0456 RimI, Acetyltransferases General function prediction only 107021898 Common - major facilitator superfamily MFS_1 Bcen_0340 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022444 Pathogen - hypothetical protein Bcen_0889 2 None None None 107024377 Common - membrane protein of unknown function Bcen_2834 61 COG1950 COG1950, Predicted membrane protein Function unknown 107024276 Common rplQ 50S ribosomal protein L17 Bcen_2732 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 107024339 Common - OmpW Bcen_2795 43 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 107022065 Common - hypothetical protein Bcen_0507 14 None None None 107022689 Common - metabolite Bcen_1136 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022939 Common - hypothetical protein Bcen_1387 4 None None None 107021613 Common - RNA polymerase sigma factor SigJ Bcen_0051 44 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107023943 Common - transcriptional regulator, LysR family Bcen_2398 159 COG0583 LysR, Transcriptional regulator Transcription 107022209 Common - Peptidase S26A, signal peptidase I Bcen_0653 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 107023869 Pathogen - hypothetical protein Bcen_2322 1 COG3211 PhoX, Predicted phosphatase General function prediction only 107023679 Common - transcriptional regulator, MarR family Bcen_2132 48 COG1846 MarR, Transcriptional regulators Transcription 162218058 Common rpsA 30S ribosomal protein S1 Bcen_0568 223 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 107023892 Common - hydroxymethylglutaryl-CoA lyase Bcen_2345 129 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 107023226 Common - potassium-transporting ATPase subunit A Bcen_1676 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 107022936 Common - glycosyl transferase, family 9 Bcen_1384 108 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107022550 Common rpmI 50S ribosomal protein L35 Bcen_0995 174 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 107024342 Common - Lysine exporter protein (LYSE/YGGA) Bcen_2798 110 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 107022892 Common - hypothetical protein Bcen_1340 2 None None None 107022379 Common - phosphate uptake regulator, PhoU Bcen_0823 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 107022834 Common - Drug resistance transporter EmrB/QacA subfamily Bcen_1282 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023965 Common - Lytic transglycosylase, catalytic Bcen_2420 159 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 107024458 Common - hypothetical protein Bcen_2916 6 None None None 107023598 Common - glycosyl transferase, family 51 Bcen_2051 15 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 107023930 Common - binding-protein-dependent transport systems inner membrane component Bcen_2384 210 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 107023521 Common - transcriptional regulator, LysR family Bcen_1974 189 COG0583 LysR, Transcriptional regulator Transcription 107022695 Common - periplasmic multidrug efflux lipoprotein precursor Bcen_1142 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 107023111 Common - periplasmic sensor signal transduction histidine kinase Bcen_1560 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 107022243 Common - Twin-arginine translocation pathway signal Bcen_0687 35 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 107022142 Common - D-amino acid dehydrogenase small subunit Bcen_0585 139 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107023864 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase Bcen_2317 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 107024109 Common - enoyl-CoA hydratase Bcen_2564 172 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107022821 Common - ABC transporter related Bcen_1269 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 107023118 Common - transcriptional regulator, LysR family Bcen_1567 181 COG0583 LysR, Transcriptional regulator Transcription 107023819 Common - lipoyl synthase Bcen_2272 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 107021907 Common - Xanthine dehydrogenase Bcen_0349 104 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 107022822 Common - hypothetical protein Bcen_1270 16 None None None 107023822 Common - transcriptional regulator, LysR family Bcen_2275 182 COG0583 LysR, Transcriptional regulator Transcription 107024192 Common - Rhs element Vgr protein Bcen_2648 49 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 107022354 Common - glutathione S-transferase-like Bcen_0798 51 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107024251 Common - OmpW Bcen_2707 65 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 107023018 Common - major facilitator superfamily MFS_1 Bcen_1466 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022315 Common - NADH:flavin oxidoreductase/NADH oxidase Bcen_0759 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 107021766 Common ruvA Holliday junction DNA helicase motor protein Bcen_0206 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 107024063 Common - transcriptional regulator, LysR family Bcen_2518 114 COG0583 LysR, Transcriptional regulator Transcription 107022353 Common - PHB de-polymerase-like Bcen_0797 43 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 107022974 Common - cytochrome bd ubiquinol oxidase, subunit I Bcen_1422 161 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 107023067 Common - extracellular solute-binding protein, family 1 Bcen_1515 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107023574 Common moaC molybdenum cofactor biosynthesis protein C Bcen_2027 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 107022153 Common - hypothetical protein Bcen_0596 11 None None None 107022851 Common - acriflavin resistance protein Bcen_1299 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 107024393 Common - CheW protein Bcen_2850 120 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 107024429 Common - helicase-like Bcen_2887 26 None None None 107023231 Common upp uracil phosphoribosyltransferase Bcen_1681 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 107023600 Common - protein of unknown function DUF1272 Bcen_2053 21 COG3813 COG3813, Uncharacterized protein conserved in bacteria Function unknown 107022063 Common - septum site-determining protein MinD Bcen_0505 140 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 107022598 Common - type II secretion system protein Bcen_1045 77 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 107023258 Common - protein of unknown function DUF306, Meta and HslJ Bcen_1708 8 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 107024127 Common - hypothetical protein Bcen_2582 10 None None None 107024317 Common secE preprotein translocase subunit SecE Bcen_2773 59 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 107022170 Pathogen - hypothetical protein Bcen_0614 1 None None None 107024261 Pathogen - hypothetical protein Bcen_2717 1 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 107021888 Common - acyl-CoA dehydrogenase-like Bcen_0330 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107023479 Common - Chromate transporter Bcen_1930 48 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 107024025 Common - periplasmic sensor signal transduction histidine kinase Bcen_2480 93 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107022060 Pathogen - hypothetical protein Bcen_0502 1 None None None 107023154 Common - hypothetical protein Bcen_1603 5 None None None 107024073 Common - aldehyde dehydrogenase Bcen_2528 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107024018 Common xerC site-specific tyrosine recombinase XerC Bcen_2473 229 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 107021900 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Bcen_0342 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 107022012 Common - mandelate racemase/muconate lactonizing enzyme Bcen_0454 62 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 107023341 Common - Lysine-arginine-ornithine-binding periplasmic protein Bcen_1792 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107023347 Common - outer membrane protein (porin)-like Bcen_1798 16 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107023906 Common - PfkB Bcen_2360 119 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 107024104 Common - transposase IS3/IS911 Bcen_2559 63 None None None 107023323 Common - transcriptional regulator, TetR family Bcen_1774 92 COG1309 AcrR, Transcriptional regulator Transcription 107023172 Common - protein of unknown function DUF1178 Bcen_1621 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 107023146 Common - dihydropyrimidine dehydrogenase Bcen_1595 139 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 107022952 Pathogen - hypothetical protein Bcen_1400 1 None None None 107023690 Common - Endoribonuclease L-PSP Bcen_2143 14 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 107023876 Common - glutathione S-transferase-like Bcen_2329 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107023829 Common - VanZ like protein Bcen_2282 13 COG5652 COG5652, Predicted integral membrane protein Function unknown 107022130 Common - RfaE bifunctional protein, domain I Bcen_0573 138 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 107022089 Common - hypothetical protein Bcen_0532 88 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 107024504 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Bcen_2962 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 107021565 Pathogen - hypothetical protein Bcen_0003 1 None None None 107021576 Common - General secretion pathway protein I Bcen_0014 12 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 107021923 Common - ornithine cyclodeaminase/mu-crystallin Bcen_0365 49 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 107023834 Common - 5'-Nucleotidase-like Bcen_2287 115 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 107022421 Common - TonB-dependent siderophore receptor Bcen_0866 124 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 107022528 Common - flavodoxin/nitric oxide synthase Bcen_0973 108 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 107022716 Common - lysine/ornithine N-monooxygenase Bcen_1163 53 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 107024035 Common - Alcohol dehydrogenase, zinc-binding Bcen_2490 176 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 107022019 Common - Chromate transporter Bcen_0461 109 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 107023794 Common - Phosphotransferase system, HPr Bcen_2247 153 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 107022093 Common - Peptidase M1, alanyl aminopeptidase Bcen_0536 158 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 107024169 Common - OmpA/MotB Bcen_2625 160 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 107023190 Common tpiA triosephosphate isomerase Bcen_1639 231 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 107022014 Common - transcriptional regulator, LysR family Bcen_0456 190 COG0583 LysR, Transcriptional regulator Transcription 107021816 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Bcen_0256 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 107021823 Common - RNA-binding S4 Bcen_0263 112 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 107024040 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Bcen_2495 125 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 162218063 Common proA gamma-glutamyl phosphate reductase Bcen_0174 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 107022758 Common - extracellular solute-binding protein, family 1 Bcen_1205 12 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 107023911 Common - Dihydroneopterin aldolase Bcen_2365 48 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 107023351 Common - Beta-glucosidase Bcen_1802 96 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 107023772 Common - cytochrome oxidase assembly Bcen_2225 77 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 107023430 Common - putative acetyltransferase Bcen_1881 43 COG0456 RimI, Acetyltransferases General function prediction only 107021690 Common aroE shikimate 5-dehydrogenase Bcen_0130 213 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 107021956 Common - transposase, mutator type Bcen_0398 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023274 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_1724 75 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 107022224 Common - transcriptional regulator, XRE family Bcen_0668 29 COG1396 HipB, Predicted transcriptional regulators Transcription 107022136 Common - alpha/beta hydrolase fold Bcen_0579 125 COG2267 PldB, Lysophospholipase Lipid metabolism 107024386 Common - hypothetical protein Bcen_2843 5 None None None 107024355 Common - Glucarate dehydratase Bcen_2811 46 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 107024467 Common - ethanolamine ammonia-lyase small subunit Bcen_2925 52 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 107022483 Common - transcriptional regulator, LysR family Bcen_0928 189 COG0583 LysR, Transcriptional regulator Transcription 107021990 Common - Rhodanese-like Bcen_0432 150 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 107023785 Common - Appr-1-p processing Bcen_2238 107 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 107022723 Common - putative transcriptional regulators, CopG/Arc/MetJ family Bcen_1170 9 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 107022981 Common - naphthoate synthase Bcen_1429 177 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 107021603 Common - outer membrane protein (porin)-like Bcen_0041 18 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107021610 Common - protein of unknown function DUF323 Bcen_0048 77 COG1262 COG1262, Uncharacterized conserved protein Function unknown 107023845 Common - fumarylacetoacetate (FAA) hydrolase Bcen_2298 75 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 107024093 Common - hypothetical protein Bcen_2548 5 None None None 107023365 Common - transcriptional regulator, XRE family Bcen_1816 41 COG1396 HipB, Predicted transcriptional regulators Transcription 107023292 Common - Chromate transporter Bcen_1743 102 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 107023507 Common - Cyclopropane-fatty-acyl-phospholipid synthase Bcen_1958 139 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 107023776 Common - hypothetical protein Bcen_2229 15 None None None 107022654 Pathogen - hypothetical protein Bcen_1101 1 None None None 107022237 Common - glycosyl transferase, group 1 Bcen_0681 177 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107022631 Common - hypothetical protein Bcen_1078 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 107022706 Common - MbtH-like protein Bcen_1153 31 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 107023083 Common - glycosyl hydrolase, BNR repeat Bcen_1532 27 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 107022669 Common - nodulation ABC transporter NodI Bcen_1116 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 107022802 Common - CBS domain protein Bcen_1249 133 COG0517 COG0517, FOG: CBS domain General function prediction only 107024241 Common - FAD dependent oxidoreductase Bcen_2697 58 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107021855 Common - short-chain dehydrogenase/reductase SDR Bcen_0297 222 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107022583 Common - dihydrolipoamide dehydrogenase Bcen_1030 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 107022877 Common - MgtC/SapB transporter Bcen_1325 104 COG1285 SapB, Uncharacterized membrane protein Function unknown 107023439 Common - DNA repair protein RadC Bcen_1890 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 107023553 Common - Peptidase S1C, Do Bcen_2006 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 107023399 Common - transcriptional regulator, LysR family Bcen_1850 182 COG0583 LysR, Transcriptional regulator Transcription 107023492 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Bcen_1943 193 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 107023500 Common - protein of unknown function UPF0079 Bcen_1951 191 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 107023423 Common - hypothetical protein Bcen_1874 4 None None None 107023569 Common - Lipopolysaccharide heptosyltransferase II Bcen_2022 94 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107023706 Common - Phasin Bcen_2159 15 None None None 107023812 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Bcen_2265 184 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 107023215 Common - protein of unknown function DUF924 Bcen_1665 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 107021845 Common - polysaccharide export protein Bcen_0287 79 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 107022284 Common - ABC transporter related Bcen_0728 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 107023762 Common - hypothetical protein Bcen_2215 24 COG4544 COG4544, Uncharacterized conserved protein Function unknown 107022574 Common infB translation initiation factor IF-2 Bcen_1020 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 107023390 Common cobS cobalamin synthase Bcen_1841 133 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 107022372 Common - ATP-dependent metalloprotease FtsH Bcen_0816 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 107022593 Common - Flp pilus assembly CpaB Bcen_1040 33 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 107024204 Pathogen - hypothetical protein Bcen_2660 1 None None None 107023848 Common - hypothetical protein Bcen_2301 10 None None None 107021894 Common - major facilitator superfamily MFS_1 Bcen_0336 220 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022302 Common - protein of unknown function DUF891 Bcen_0746 30 COG4679 COG4679, Phage-related protein Function unknown 107023342 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1793 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 107021639 Common murC UDP-N-acetylmuramate--L-alanine ligase Bcen_0078 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 107024090 Pathogen - hypothetical protein Bcen_2545 1 None None None 107022905 Common - protein of unknown function DUF892 Bcen_1353 20 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 107022731 Common - magnesium chelatase, ChlI subunit Bcen_1178 96 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 107022308 Common - binding-protein-dependent transport systems inner membrane component Bcen_0752 187 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 107024475 Common - transcriptional regulator, PadR-like family Bcen_2933 11 COG1695 COG1695, Predicted transcriptional regulators Transcription 107022873 Common - Rieske (2Fe-2S) region Bcen_1321 30 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 107024443 Common - methylated-DNA--protein-cysteine methyltransferase Bcen_2901 209 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 107023075 Common - binding-protein-dependent transport systems inner membrane component Bcen_1524 154 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 107023262 Common - polyhydroxyalkanoate depolymerase, intracellular Bcen_1712 45 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 107024007 Pathogen - hypothetical protein Bcen_2462 1 None None None 107022588 Common - hypothetical protein Bcen_1035 15 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 107024362 Common - RNA-directed DNA polymerase (Reverse transcriptase) Bcen_2818 93 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 107022414 Common - hypothetical protein Bcen_0859 82 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 107021657 Common - protein of unknown function DUF21 Bcen_0097 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 107021814 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Bcen_0254 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 107021853 Common - lipopolysaccharide biosynthesis Bcen_0295 38 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 107023589 Common - two component transcriptional regulator, winged helix family Bcen_2042 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107023297 Common - DNA topoisomerase IV subunit B Bcen_1748 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 107022814 Common - extracellular solute-binding protein, family 3 Bcen_1262 165 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107022327 Common - major facilitator superfamily MFS_1 Bcen_0771 130 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107024225 Common - histidinol-phosphate aminotransferase Bcen_2681 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 107022250 Common - hypothetical protein Bcen_0694 17 None None None 107022295 Common - protein of unknown function DUF6, transmembrane Bcen_0739 154 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 107024132 Common - putative ABC transporter ATP-binding protein Bcen_2587 246 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 107022433 Common - putative FecR Bcen_0878 36 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 107023632 Pathogen - hypothetical protein Bcen_2085 1 None None None 107023035 Common - hypothetical protein Bcen_1483 20 None None None 107023392 Common - ABC transporter related Bcen_1843 220 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 107022495 Common - thiamine pyrophosphate enzyme-like TPP-binding Bcen_0940 219 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 107024000 Common - flagellar hook-length control protein Bcen_2455 42 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 107022090 Pathogen - Transglycosylase-associated protein Bcen_0533 1 COG2261 COG2261, Predicted membrane protein Function unknown 107023641 Common - Glyoxalase I Bcen_2094 136 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 107023601 Common - GntR-like Bcen_2054 104 COG2186 FadR, Transcriptional regulators Transcription 107022165 Pathogen - hypothetical protein Bcen_0609 1 None None None 107022968 Common - serine/threonine protein kinase Bcen_1416 80 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 107021675 Pathogen - hypothetical protein Bcen_0115 1 None None None 107022956 Common - Linocin_M18 bacteriocin protein Bcen_1404 20 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 107023586 Common - hypothetical protein Bcen_2039 12 None None None 107024187 Common - hypothetical protein Bcen_2643 44 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 107022560 Common - Antibiotic biosynthesis monooxygenase Bcen_1006 52 COG1359 COG1359, Uncharacterized conserved protein Function unknown 107022377 Common pstA phosphate transporter permease subunit Bcen_0821 231 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 107023052 Pathogen - hypothetical protein Bcen_1500 1 None None None 107024302 Common rplD 50S ribosomal protein L4 Bcen_2758 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 107022868 Common - sugar efflux transporter Bcen_1316 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107021873 Common - hypothetical protein Bcen_0315 69 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 107023131 Common groEL chaperonin GroEL Bcen_1580 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 107024430 Common - hypothetical protein Bcen_2888 4 None None None 107023549 Common - transcriptional regulator, AraC family Bcen_2002 122 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107022365 Common - carbamoyl phosphate synthase small subunit Bcen_0809 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 107024049 Common - organic radical activating enzymes-like Bcen_2504 151 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 107023633 Common - transporter-associated region Bcen_2086 217 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 107023453 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Bcen_1904 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 107023064 Common - major facilitator superfamily MFS_1 Bcen_1512 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022924 Common - transport-associated Bcen_1372 34 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 107021649 Common - protein of unknown function DUF815 Bcen_0089 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 107023684 Common - hypothetical protein Bcen_2137 4 None None None 107022343 Common - malonate transporter, MadM subunit Bcen_0787 11 None None None 162218051 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Bcen_1880 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 107022155 Common - Ste24 endopeptidase Bcen_0598 63 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 107023144 Common - dihydropyrimidinase Bcen_1593 198 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 107024372 Common - Extracellular ligand-binding receptor Bcen_2829 145 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107021669 Common - cytochrome c assembly protein Bcen_0109 100 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 107021609 Common - hypothetical protein Bcen_0047 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 107022512 Common - hypothetical protein Bcen_0957 2 None None None 107022993 Common - 2-keto-4-pentenoate hydratase-like Bcen_1441 57 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 107024487 Common - Prephenate dehydratase Bcen_2945 145 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107021945 Common - phospholipid/glycerol acyltransferase Bcen_0387 127 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 107023880 Common - PilT protein-like Bcen_2333 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 107021584 Common - transcriptional regulator, MarR family Bcen_0022 149 COG1846 MarR, Transcriptional regulators Transcription 107021961 Pathogen - hypothetical protein Bcen_0403 1 None None None 107023499 Common - 4Fe-4S cluster binding Bcen_1950 134 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 107022577 Common - Drug resistance transporter EmrB/QacA subfamily Bcen_1023 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107024415 Pathogen - hypothetical protein Bcen_2873 1 None None None 107024274 Common - Protein-disulfide reductase Bcen_2730 127 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 107024315 Common rplK 50S ribosomal protein L11 Bcen_2771 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 107024117 Common - anthranilate synthase component II Bcen_2572 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 107021593 Common - Flagellar motor switch FliN Bcen_0031 123 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 107023373 Common - Cobyrinic acid a,c-diamide synthase Bcen_1824 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107022855 Common benD 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Bcen_1303 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107021628 Common - ubiquinone biosynthesis protein COQ7-like Bcen_0067 50 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 107022455 Common - hypothetical protein Bcen_0900 16 None None None 107021682 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit Bcen_0122 203 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 107021700 Common araH L-arabinose transporter permease protein Bcen_0140 147 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 107023042 Common - protein of unknown function DUF1275 Bcen_1490 24 COG3619 COG3619, Predicted membrane protein Function unknown 107023853 Common - Sporulation related Bcen_2306 28 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 107021941 Common - Holliday junction resolvase-like protein Bcen_0383 182 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 107022617 Common - ROK domain protein Bcen_1064 80 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 107023887 Common - molybdopterin dehydrogenase, FAD-binding Bcen_2340 69 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 107024419 Pathogen - hypothetical protein Bcen_2877 1 None None None 107023923 Common - transcriptional regulator, XRE family with cupin sensor Bcen_2377 111 COG1396 HipB, Predicted transcriptional regulators Transcription 107021826 Common - GrpE protein Bcen_0266 229 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 107022490 Common - ABC transporter related Bcen_0935 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107023337 Common - periplasmic sensor signal transduction histidine kinase Bcen_1788 199 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107023801 Common - Mg chelatase-related protein Bcen_2254 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 107024278 Common rpsD 30S ribosomal protein S4 Bcen_2734 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 107021759 Common anmK anhydro-N-acetylmuramic acid kinase Bcen_0199 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 107022401 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Bcen_0846 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 107022255 Common - transcriptional regulator, AraC family Bcen_0699 140 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107023129 Common - Catalase Bcen_1578 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 107022183 Common - hypothetical protein Bcen_0627 3 None None None 107023526 Common - beta-lactamase Bcen_1979 123 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 107022406 Common - hypothetical protein Bcen_0851 2 None None None 107024323 Common - Phenylacetate-CoA oxygenase, PaaJ subunit Bcen_2779 42 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 107022879 Common - phospholipase D/Transphosphatidylase Bcen_1327 86 COG0398 COG0398, Uncharacterized conserved protein Function unknown 107021772 Common - glutathione S-transferase-like Bcen_0212 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107021713 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_0153 50 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 107023981 Common - nitroreductase Bcen_2436 50 COG0778 NfnB, Nitroreductase Energy production and conversion 107022916 Common - phage SPO1 DNA polymerase-related protein Bcen_1364 149 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 107021786 Common - protein of unknown function DUF330 Bcen_0226 18 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 107022608 Common - transcriptional regulator, TetR family Bcen_1055 64 COG1309 AcrR, Transcriptional regulator Transcription 107023269 Common - cytochrome c, class I Bcen_1719 45 COG2863 COG2863, Cytochrome c553 Energy production and conversion 107022052 Common - Smr protein/MutS2 Bcen_0494 94 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 107024129 Common - protein of unknown function DUF661 Bcen_2584 14 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 107023988 Common - protein of unknown function DUF182 Bcen_2443 115 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 107021707 Common - thiamine monophosphate kinase Bcen_0147 177 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 107023446 Common - MscS Mechanosensitive ion channel Bcen_1897 196 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 107022115 Common - phosphoglycolate phosphatase Bcen_0558 116 COG0546 Gph, Predicted phosphatases General function prediction only 107024258 Common aroB 3-dehydroquinate synthase Bcen_2714 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 107022861 Common - Phenazine biosynthesis PhzC/PhzF protein Bcen_1309 79 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 107023542 Common - carbohydrate kinase, FGGY Bcen_1995 172 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 107022193 Common - Maf-like protein Bcen_0637 184 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 107023057 Common - two component heavy metal response transcriptional regulator, winged helix family Bcen_1505 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107022190 Common - Rieske (2Fe-2S) region Bcen_0634 37 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 107023536 Common - ferric uptake regulator, Fur family Bcen_1989 115 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 107023158 Common - two component transcriptional regulator, LuxR family Bcen_1607 68 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 107023615 Common - MIP family channel proteins Bcen_2068 130 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 107021615 Pathogen - hypothetical protein Bcen_0054 1 None None None 107024111 Common - Phenylacetate-CoA ligase Bcen_2566 115 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 107023955 Common flgC flagellar basal body rod protein FlgC Bcen_2410 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 107022770 Common - major facilitator superfamily MFS_1 Bcen_1217 175 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022881 Pathogen - hypothetical protein Bcen_1329 1 None None None 107024369 Common - histone-like nucleoid-structuring protein H-NS Bcen_2825 22 COG2916 Hns, DNA-binding protein H-NS General function prediction only 107021993 Common - coproporphyrinogen III oxidase Bcen_0435 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 107024493 Common - F0F1 ATP synthase subunit alpha Bcen_2951 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 107023316 Common - Phytanoyl-CoA dioxygenase Bcen_1767 10 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 107023960 Common - peptidase M24 Bcen_2415 166 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 107021652 Common - hypothetical protein Bcen_0092 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 107022116 Common - 3-demethylubiquinone-9 3-methyltransferase Bcen_0559 137 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 107023047 Common - ABC transporter related Bcen_1495 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 107022774 Pathogen - hypothetical protein Bcen_1221 1 None None None 107023647 Common - aminoglycoside phosphotransferase Bcen_2100 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 107023818 Common - Taurine ABC transporter, periplasmic binding protein Bcen_2271 110 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 107021695 Common - 2-keto-3-deoxy-galactonokinase Bcen_0135 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 107024135 Common - peptidase M24 Bcen_2590 201 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 107022856 Common - oxidoreductase FAD/NAD(P)-binding Bcen_1304 186 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 107024283 Common secY preprotein translocase subunit SecY Bcen_2739 218 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 107024379 Common fliA flagellar biosynthesis sigma factor Bcen_2836 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 107024356 Pathogen - hypothetical protein Bcen_2812 1 None None None 107024406 Common - TonB-dependent siderophore receptor Bcen_2864 91 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 107024171 Pathogen - hypothetical protein Bcen_2627 1 None None None 107022330 Common - major facilitator superfamily MFS_1 Bcen_0774 113 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023305 Pathogen - hypothetical protein Bcen_1756 1 None None None 107023413 Common - nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like Bcen_1864 166 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 107022746 Common cobH precorrin-8X methylmutase Bcen_1193 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 107022071 Common - TonB-like Bcen_0513 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 107022104 Common - hypothetical protein Bcen_0547 7 None None None 107021747 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_0187 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107023228 Common - Alcohol dehydrogenase, zinc-binding Bcen_1678 197 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 107024523 Common - periplasmic sensor signal transduction histidine kinase Bcen_2981 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107022067 Common - Cl- channel, voltage gated Bcen_0509 152 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 107023466 Common - high-affinity nickel-transporter Bcen_1917 38 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 107024156 Pathogen - hypothetical protein Bcen_2612 1 None None None 107022179 Common - Na+/H+ antiporter NhaD and related arsenite permeases-like Bcen_0623 27 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 107023973 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Bcen_2428 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 107022485 Common - NUDIX hydrolase Bcen_0930 128 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 107021754 Common - OsmC-like protein Bcen_0194 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 107023513 Common - flavin reductase-like, FMN-binding Bcen_1964 124 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 107021920 Common - Drug resistance transporter EmrB/QacA subfamily Bcen_0362 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107021791 Common - YceI Bcen_0231 93 COG2353 COG2353, Uncharacterized conserved protein Function unknown 107023021 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Bcen_1469 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 107023028 Common - metal-dependent phosphohydrolase Bcen_1476 17 None None None 162218060 Common - hypothetical protein Bcen_0347 32 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022624 Common - oxidoreductase-like Bcen_1071 105 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 107022149 Common trmD tRNA (guanine-N(1)-)-methyltransferase Bcen_0592 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 107024218 Common hisE phosphoribosyl-ATP pyrophosphatase Bcen_2674 176 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 107022454 Common - cellulose synthase operon C-like Bcen_0899 33 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 107023120 Pathogen - hypothetical protein Bcen_1569 1 None None None 107022277 Common - phosphatase-like Bcen_0721 25 COG3211 PhoX, Predicted phosphatase General function prediction only 107023420 Common - transcriptional regulator, LysR family Bcen_1871 182 COG0583 LysR, Transcriptional regulator Transcription 107023211 Common - transcriptional regulator, TetR family Bcen_1661 53 COG1309 AcrR, Transcriptional regulator Transcription 107022394 Common - phage terminase, small subunit, putative, P27 Bcen_0839 2 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 107023009 Common - Aldose 1-epimerase Bcen_1457 90 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 107022467 Common - transcriptional regulator, LysR family Bcen_0912 166 COG0583 LysR, Transcriptional regulator Transcription 107022369 Common - hypothetical protein Bcen_0813 15 None None None 107022023 Common - Silent information regulator protein Sir2 Bcen_0465 139 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 107023454 Common - protein of unknown function DUF347 Bcen_1905 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 107023249 Common - glycosyl transferase, family 9 Bcen_1699 84 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107022057 Common - hypothetical protein Bcen_0499 14 COG5460 COG5460, Uncharacterized conserved protein Function unknown 107021742 Common - FAD dependent oxidoreductase Bcen_0182 82 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107021689 Common - ribonuclease II Bcen_0129 103 COG0557 VacB, Exoribonuclease R Transcription 107022044 Common - glucokinase Bcen_0486 161 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 107023687 Pathogen - hypothetical protein Bcen_2140 1 None None None 107022313 Common - Alcohol dehydrogenase, zinc-binding Bcen_0757 164 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 107024149 Common - major facilitator superfamily MFS_1 Bcen_2605 99 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107023953 Common flgE flagellar hook protein FlgE Bcen_2408 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 107023234 Common - coproporphyrinogen III oxidase Bcen_1684 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 107023650 Common - thioesterase superfamily Bcen_2103 132 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 107024517 Common - adenylate cyclase Bcen_2975 7 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 107022794 Common - Acyl-CoA dehydrogenase, type 2-like Bcen_1241 68 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022767 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_1214 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 107022264 Common - extracellular solute-binding protein, family 3 Bcen_0708 170 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107022783 Common - alpha/beta hydrolase fold Bcen_1230 164 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107023000 Common - Lysine exporter protein (LYSE/YGGA) Bcen_1448 103 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 107022039 Common - riboflavin biosynthesis protein RibD Bcen_0481 231 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 107022032 Common - Lytic transglycosylase, catalytic Bcen_0474 33 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 107024506 Common - ABC transporter related Bcen_2964 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107022225 Common - hypothetical protein Bcen_0669 21 None None None 107021830 Common - para-aminobenzoate synthase, component I Bcen_0270 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 107024159 Common - Alcohol dehydrogenase, zinc-binding Bcen_2615 159 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 107024233 Common - toluene tolerance Bcen_2689 70 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 107022784 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase Bcen_1231 181 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 107023814 Common - Gamma-glutamyltransferase Bcen_2267 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 107024121 Common - uracil-DNA glycosylase Bcen_2576 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 107023480 Common - Superoxide dismutase Bcen_1931 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 107021598 Common - ABC nitrate/sulfonate/bicarbonate transporter, periplasmic ligand binding protein Bcen_0036 46 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 107022148 Common rimM 16S rRNA-processing protein Bcen_0591 126 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 107024157 Common - peptidase M1, membrane alanine aminopeptidase Bcen_2613 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 107024138 Common hemA glutamyl-tRNA reductase Bcen_2593 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 107022108 Common - hypothetical protein Bcen_0551 21 None None None 107022051 Common - protein of unknown function UPF0126 Bcen_0493 103 COG2860 COG2860, Predicted membrane protein Function unknown 107022766 Common - pyruvate carboxyltransferase Bcen_1213 204 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 107022773 Common - FR47-like Bcen_1220 15 COG3393 COG3393, Predicted acetyltransferase General function prediction only 107024488 Pathogen - hypothetical protein Bcen_2946 1 None None None 107022022 Common - hypothetical protein Bcen_0464 9 None None None 107022860 Common - transcriptional regulator, winged helix family Bcen_1308 111 COG3903 COG3903, Predicted ATPase General function prediction only 107023017 Common - Chloride peroxidase Bcen_1465 121 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107022248 Common - Radical SAM Bcen_0692 93 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 107023214 Common - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Bcen_1664 24 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 107023961 Common - transcriptional regulator, XRE family with cupin sensor Bcen_2416 87 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 107022203 Common - RNA polymerase sigma factor RpoE Bcen_0647 173 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107024502 Common - Cobyrinic acid a,c-diamide synthase Bcen_2960 223 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107021755 Pathogen - hypothetical protein Bcen_0195 1 None None None 107022459 Common - hypothetical protein Bcen_0904 18 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 107022792 Common - cytochrome c, class I Bcen_1239 27 COG3258 COG3258, Cytochrome c Energy production and conversion 107023884 Common - glutathione S-transferase-like Bcen_2337 73 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107022846 Common - cytochrome c, class I Bcen_1294 72 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 107024142 Common - Glutaredoxin-related protein Bcen_2597 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 107021668 Common - signal recognition particle protein Bcen_0108 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 162218064 Common - DNA-binding transcriptional regulator CynR Bcen_0161 190 COG0583 LysR, Transcriptional regulator Transcription 107022910 Common - CBS domain containing membrane protein Bcen_1358 170 COG0517 COG0517, FOG: CBS domain General function prediction only 107023518 Common - major facilitator superfamily MFS_1 Bcen_1969 187 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107024023 Common hslU ATP-dependent protease ATP-binding subunit Bcen_2478 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 107022207 Common - glutaredoxin 2 Bcen_0651 24 None None None 107023443 Common - nicotinate-nucleotide pyrophosphorylase Bcen_1894 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 107022828 Pathogen - phosphocarrier HPr protein Bcen_1276 1 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 107024398 Common - transcriptional activator FlhC Bcen_2855 27 None None None 107021642 Common - cell division protein FtsA Bcen_0081 178 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 107023156 Common - GCN5-related N-acetyltransferase Bcen_1605 20 COG0456 RimI, Acetyltransferases General function prediction only 107024178 Common - protein of unknown function DUF1305 Bcen_2634 43 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 107023527 Common - transcriptional regulator, LysR family Bcen_1980 159 COG0583 LysR, Transcriptional regulator Transcription 107021918 Pathogen - hypothetical protein Bcen_0360 1 None None None 107021931 Common - putative transmembrane anti-sigma factor Bcen_0373 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 107022810 Common - ABC transporter related Bcen_1258 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 107021787 Common - Mammalian cell entry related Bcen_0227 65 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 107021730 Common - Biopolymer transport protein ExbD/TolR Bcen_0170 120 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 107023538 Common - ABC transporter related Bcen_1991 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 107023361 Common - bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase Bcen_1812 47 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 107023531 Common - binding-protein-dependent transport systems inner membrane component Bcen_1984 162 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 107022928 Common - hypothetical protein Bcen_1376 3 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 107022544 Common - alpha/beta hydrolase fold Bcen_0989 68 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107022114 Pathogen - hypothetical protein Bcen_0557 1 None None None 107022616 Common - ABC transporter related Bcen_1063 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 107022072 Pathogen - hypothetical protein Bcen_0514 2 None None None 107021972 Common - Phosphomannomutase Bcen_0414 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 107021745 Common - Glu/Leu/Phe/Val dehydrogenase Bcen_0185 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 107022429 Pathogen - hypothetical protein Bcen_0874 1 None None None 107023741 Common - conserved hypothetical protein 95 Bcen_2194 194 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 107022270 Common - protein of unknown function DUF88 Bcen_0714 85 COG1432 COG1432, Uncharacterized conserved protein Function unknown 107023124 Pathogen - hypothetical protein Bcen_1573 1 None None None 107022777 Pathogen - hypothetical protein Bcen_1224 1 None None None 107023478 Common - transcriptional regulator, Crp/Fnr family Bcen_1929 127 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 107024176 Common - ATPase AAA-2 Bcen_2632 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 107023221 Common - protein of unknown function DUF333 Bcen_1671 10 COG3042 Hlx, Putative hemolysin General function prediction only 107022632 Common - small multidrug resistance protein Bcen_1079 140 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 107024364 Common - rare lipoprotein A Bcen_2820 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 107022675 Common - Sulfate ABC transporter, permease protein CysT Bcen_1122 209 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 107023596 Common - hypothetical protein Bcen_2049 9 COG4104 COG4104, Uncharacterized conserved protein Function unknown 107024434 Pathogen - hypothetical protein Bcen_2892 1 COG5234 CIN1, Beta-tubulin folding cofactor D Posttranslational modification, protein turnover, chaperones / Cytoskeleton 107023616 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Bcen_2069 236 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 107024194 Pathogen - hypothetical protein Bcen_2650 1 None None None 107022725 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase Bcen_1172 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 107023036 Common - hypothetical protein Bcen_1484 4 None None None 107021926 Pathogen - hypothetical protein Bcen_0368 1 None None None 107024373 Common - 2-nitropropane dioxygenase, NPD Bcen_2830 87 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 107021833 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Bcen_0273 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 107024297 Common rpsC 30S ribosomal protein S3 Bcen_2753 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 107022138 Common - binding-protein-dependent transport systems inner membrane component Bcen_0581 183 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 107022637 Common - ABC transporter related Bcen_1084 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 107021618 Pathogen - hypothetical protein Bcen_0057 1 None None None 107023452 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Bcen_1903 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 107022061 Pathogen - GCN5-related N-acetyltransferase Bcen_0503 1 None None None 107024186 Common - protein of unknown function DUF876 Bcen_2642 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 107024526 Common - glutamine amidotransferase Bcen_2984 135 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 107023069 Common - histidinol dehydrogenase Bcen_1517 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 107023432 Common - ABC transporter related Bcen_1883 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107022872 Common - hypothetical protein Bcen_1320 3 None None None 107022462 Common - Pirin-like Bcen_0907 143 COG1741 COG1741, Pirin-related protein General function prediction only 107022332 Common - L-serine ammonia-lyase Bcen_0776 191 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 107023418 Common - short-chain dehydrogenase/reductase SDR Bcen_1869 227 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 107023380 Common panC pantoate--beta-alanine ligase Bcen_1831 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 107023950 Common flgH flagellar basal body L-ring protein Bcen_2405 100 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 107023980 Common - AAA ATPase, central region Bcen_2435 180 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 107023184 Common - NADH dehydrogenase subunit E Bcen_1633 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 107024285 Common rpmD 50S ribosomal protein L30 Bcen_2741 149 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 107022819 Common - binding-protein-dependent transport systems inner membrane component Bcen_1267 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 107023985 Common - putative signal transduction histidine kinase Bcen_2440 106 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 107022184 Common - MoeA-like, domain I and II Bcen_0628 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 107024324 Common - Phenylacetate-CoA oxygenase/reductase, PaaK subunit Bcen_2780 134 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 107022458 Common - Cellulose synthase (UDP-forming) Bcen_0903 83 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 107022991 Pathogen - hypothetical protein Bcen_1439 1 None None None 107022572 Common - hypothetical protein Bcen_1018 157 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 107023795 Common - PTS system fructose subfamily IIA component Bcen_2248 88 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 107023357 Common - major facilitator superfamily MFS_1 Bcen_1808 149 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107024271 Common - cytochrome c, class I Bcen_2727 64 COG2863 COG2863, Cytochrome c553 Energy production and conversion 107022526 Common - FAD linked oxidase-like Bcen_0971 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 107023925 Common - peptidase C26 Bcen_2379 114 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 107021843 Common - MscS Mechanosensitive ion channel Bcen_0284 151 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 107024418 Common - hypothetical protein Bcen_2876 10 COG4278 COG4278, Uncharacterized conserved protein Function unknown 107022511 Common - periplasmic sensor signal transduction histidine kinase Bcen_0956 219 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 107021988 Common - inner-membrane translocator Bcen_0430 147 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 107022747 Common - Precorrin-3B synthase Bcen_1194 37 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 107021818 Common - Glutamate-ammonia-ligase adenylyltransferase Bcen_0258 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 107022006 Common - Phage-plasmid primase P4-like Bcen_0448 58 COG3378 COG3378, Predicted ATPase General function prediction only 107024305 Common - elongation factor Tu Bcen_2761 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 107022049 Common - binding-protein-dependent transport systems inner membrane component Bcen_0491 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 107024058 Common def peptide deformylase Bcen_2513 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 107021982 Common - Urease accessory protein UreD Bcen_0424 75 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 107022347 Common - malonate decarboxylase gamma subunit Bcen_0791 24 None None None 107024167 Pathogen - hypothetical protein Bcen_2623 1 None None None 107023746 Common - hypothetical protein Bcen_2199 4 None None None 107022241 Common - GntR-like Bcen_0685 127 COG2186 FadR, Transcriptional regulators Transcription 107023063 Common - hypothetical protein Bcen_1511 25 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 107022867 Common - short-chain dehydrogenase/reductase SDR Bcen_1315 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023166 Common - enoyl-CoA hydratase Bcen_1615 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107023827 Common - hydrolase of the alpha/beta superfamily-like Bcen_2280 76 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 107022957 Pathogen - hypothetical protein Bcen_1405 1 None None None 107021810 Common - FAD linked oxidase-like Bcen_0250 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 107022948 Common - hypothetical protein Bcen_1396 2 None None None 107023638 Common - D,D-heptose 1,7-bisphosphate phosphatase Bcen_2091 127 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 107023765 Common - protein of unknown function DUF534 Bcen_2218 60 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 162218059 Common - seryl-tRNA synthetase Bcen_0500 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 107022581 Common kgd alpha-ketoglutarate decarboxylase Bcen_1028 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 107022564 Pathogen - hypothetical protein Bcen_1010 1 None None None 107023313 Common - hypothetical protein Bcen_1764 61 None None None 107021850 Common - ABC transporter related Bcen_0292 248 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 107023959 Common - FlgN Bcen_2414 4 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 107021663 Common - hypothetical protein Bcen_0103 13 None None None 107023820 Common lipB lipoyltransferase Bcen_2273 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 107023374 Common - OmpA/MotB Bcen_1825 161 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 107022167 Common fumC fumarate hydratase Bcen_0611 204 COG0114 FumC, Fumarase Energy production and conversion 107023207 Common - hypothetical protein Bcen_1657 17 None None None 107023497 Common xerD site-specific tyrosine recombinase XerD Bcen_1948 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 107023091 Common - L-fucose permease Bcen_1540 48 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 107021711 Pathogen - hypothetical protein Bcen_0151 1 None None None 107024328 Common - transcriptional regulator, AsnC family Bcen_2784 158 COG1522 Lrp, Transcriptional regulators Transcription 107024131 Common - transcriptional regulator, LysR family Bcen_2586 169 COG0583 LysR, Transcriptional regulator Transcription 107022088 Common - hypothetical protein Bcen_0531 3 None None None 107023265 Common - endonuclease III Bcen_1715 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 107023077 Common - hypothetical protein Bcen_1526 10 None None None 107022279 Pathogen - hypothetical protein Bcen_0723 1 None None None 107024006 Common - protein of unknown function DUF6, transmembrane Bcen_2461 24 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 107023916 Common - transcriptional regulator-like Bcen_2370 38 COG2944 COG2944, Predicted transcriptional regulator Transcription 107023890 Common - protein of unknown function DUF1234 Bcen_2343 55 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 107022320 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Bcen_0764 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 107022980 Common - AMP-dependent synthetase and ligase Bcen_1428 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 107022592 Common - TadE-like Bcen_1039 18 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 107024216 Common - histidine triad (HIT) protein Bcen_2672 230 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 107021566 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase Bcen_0004 71 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107021667 Common - hypoxanthine-guanine phosphoribosyltransferase Bcen_0107 113 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 107023788 Common - Glutaredoxin, GrxC Bcen_2241 101 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 107023810 Common - acyl-CoA dehydrogenase-like Bcen_2263 120 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107021849 Common - glycosyl transferase, group 1 Bcen_0291 22 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107022649 Common - GCN5-related N-acetyltransferase Bcen_1096 72 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 107024045 Common - Rod shape-determining protein RodA Bcen_2500 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 107023127 Pathogen - hypothetical protein Bcen_1576 1 None None None 107022972 Common - protein of unknown function UPF0187 Bcen_1420 55 COG3781 COG3781, Predicted membrane protein Function unknown 107021586 Common - Prevent-host-death protein Bcen_0024 19 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 107024112 Common - MltA Bcen_2567 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 107023086 Common - type III effector Hrp-dependent outers Bcen_1535 63 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 107021799 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Bcen_0239 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 107022265 Common - putative signal transduction protein Bcen_0709 29 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 107022979 Common - thiamineS Bcen_1427 24 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 107023843 Common - hypothetical protein Bcen_2296 13 None None None 107022294 Pathogen - hypothetical protein Bcen_0738 1 None None None 107023709 Common - Uracil-DNA glycosylase superfamily Bcen_2162 29 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 107022150 Common rplS 50S ribosomal protein L19 Bcen_0593 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 107023640 Common - protein of unknown function DUF45 Bcen_2093 155 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 107023715 Common - NUDIX hydrolase Bcen_2168 19 None None None 107024476 Common - FAD linked oxidase-like Bcen_2934 197 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 107022397 Common - Phage-plasmid primase P4-like Bcen_0842 43 COG3378 COG3378, Predicted ATPase General function prediction only 107022232 Common - protein of unknown function DUF461 Bcen_0676 74 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 107022335 Common - Integral membrane protein TerC Bcen_0779 121 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 107023734 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Bcen_2187 189 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 107023783 Common - phosphoribosyltransferase Bcen_2236 121 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 107022899 Common - Ku domain protein Bcen_1347 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 107021936 Common groEL chaperonin GroEL Bcen_0378 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 107023558 Common - Sua5/YciO/YrdC/YwlC Bcen_2011 235 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 107022985 Common - transcriptional regulator, GntR family Bcen_1433 182 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 107024452 Common - glycine cleavage system H protein Bcen_2910 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 107023700 Common - hypothetical protein Bcen_2153 19 None None None 107022505 Common - methylmalonate-semialdehyde dehydrogenase Bcen_0950 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107022694 Common - transcriptional regulator, TetR family Bcen_1141 53 COG1309 AcrR, Transcriptional regulator Transcription 107024441 Common - Integrase, catalytic region Bcen_2899 81 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 107022738 Pathogen - hypothetical protein Bcen_1185 1 None None None 107024240 Common - sulfur carrier protein ThiS Bcen_2696 5 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 107022987 Common - Extracellular ligand-binding receptor Bcen_1435 144 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107023108 Common - AMP-dependent synthetase and ligase Bcen_1557 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 162218056 Common carB carbamoyl phosphate synthase large subunit Bcen_0811 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 107023566 Common - AzlC-like Bcen_2019 65 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 107021866 Common - plasmid-related protein Bcen_0308 18 None None None 107022303 Common - protein of unknown function DUF6, transmembrane Bcen_0747 54 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 107024465 Common - major facilitator superfamily MFS_1 Bcen_2923 171 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107024252 Common ugpQ cytoplasmic glycerophosphodiester phosphodiesterase Bcen_2708 98 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 107024269 Common - cytochrome c assembly protein Bcen_2725 142 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 107022586 Common - hypothetical protein Bcen_1033 30 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 107023175 Common - NADH dehydrogenase subunit N Bcen_1624 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 107023236 Common - Iojap-related protein Bcen_1686 198 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 107024330 Pathogen - hypothetical protein Bcen_2786 1 None None None 107023505 Common - UBA/THIF-type NAD/FAD binding fold Bcen_1956 154 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 107023210 Common - diacylglycerol kinase Bcen_1660 205 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 107021908 Common - xanthine and CO dehydrogenases maturation factor XdhC/CoxF family-like Bcen_0350 72 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 107022311 Pathogen - hypothetical protein Bcen_0755 1 None None None 107023945 Common flgL flagellar hook-associated protein FlgL Bcen_2400 87 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 107023287 Common - protein of unknown function DUF6, transmembrane Bcen_1738 75 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 107022488 Common - inner-membrane translocator Bcen_0933 53 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 107024202 Common - TrbL/VirB6 plasmid conjugal transfer protein Bcen_2658 22 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 107023368 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Bcen_1819 155 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 107023196 Common - Carbonate dehydratase Bcen_1646 148 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 107022720 Common - hypothetical protein Bcen_1167 6 COG4849 COG4849, Uncharacterized protein conserved in bacteria Function unknown 107022389 Common - uncharacterized small conserved protein Bcen_0834 11 COG5626 COG5626, Uncharacterized small conserved protein Function unknown 107023435 Common - inner-membrane translocator Bcen_1886 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 107023771 Common - protoheme IX farnesyltransferase Bcen_2224 190 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 107021735 Common - conserved hypothetical protein 701 Bcen_0175 94 COG1981 COG1981, Predicted membrane protein Function unknown 107023673 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_2126 16 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 107021953 Common - ABC transporter related Bcen_0395 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 162218048 Common gltD glutamate synthase subunit beta Bcen_2704 184 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 107022318 Common - 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) Bcen_0762 153 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 107023759 Common - transcriptional regulator, GntR family Bcen_2212 130 COG2188 PhnF, Transcriptional regulators Transcription 107021820 Common ppnK inorganic polyphosphate/ATP-NAD kinase Bcen_0260 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 107024383 Common flhB flagellar biosynthesis protein FlhB Bcen_2840 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 107023755 Common - transposase IS116/IS110/IS902 Bcen_2208 64 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021805 Common ubiA 4-hydroxybenzoate octaprenyltransferase Bcen_0245 178 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 107023545 Common - Hydrophobe/amphiphile efflux-1 HAE1 Bcen_1998 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 107022664 Common - transcriptional regulator, LysR family Bcen_1111 188 COG0583 LysR, Transcriptional regulator Transcription 107023281 Common - hypothetical protein Bcen_1732 4 None None None 107023464 Common - protein of unknown function DUF192 Bcen_1915 78 COG1430 COG1430, Uncharacterized conserved protein Function unknown 107021901 Common - transcriptional regulator, LysR family Bcen_0343 173 COG0583 LysR, Transcriptional regulator Transcription 107023119 Pathogen - hypothetical protein Bcen_1568 1 None None None 107024308 Common rpsL 30S ribosomal protein S12 Bcen_2764 237 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 107023800 Common - protein of unknown function DUF526 Bcen_2253 53 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 107022853 Common - Feruloyl esterase Bcen_1301 20 None None None 107023335 Common - binding-protein-dependent transport systems inner membrane component Bcen_1786 141 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 107021702 Common - Aldose 1-epimerase Bcen_0142 37 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 107024495 Common - F0F1 ATP synthase subunit B Bcen_2953 124 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 107022878 Pathogen - hypothetical protein Bcen_1326 1 None None None 107022017 Common - methylmalonyl-CoA decarboxylase Bcen_0459 116 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 107021947 Common - dTDP-glucose 4,6-dehydratase Bcen_0389 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 107023594 Common - ThiJ/PfpI Bcen_2047 94 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107022801 Common - hypothetical protein Bcen_1248 7 None None None 107022926 Common - NAD-dependent epimerase/dehydratase Bcen_1374 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107023444 Common - quinolinate synthetase Bcen_1895 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 107023489 Common - hypothetical protein Bcen_1940 19 None None None 107022173 Common - AzlC-like Bcen_0617 111 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 107021709 Common - guanine-specific ribonuclease N1 and T1 Bcen_0149 25 COG4290 COG4290, Guanyl-specific ribonuclease Sa Nucleotide transport and metabolism 107021812 Common - cobalamin adenosyltransferase Bcen_0252 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 107021943 Common pyrB aspartate carbamoyltransferase catalytic subunit Bcen_0385 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 107023798 Common - ammonium transporter Bcen_2251 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 107021606 Pathogen - hypothetical protein Bcen_0044 1 None None None 107023591 Common - major facilitator superfamily MFS_1 Bcen_2044 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023971 Common - GumN Bcen_2426 38 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 107022112 Common - transcriptional regulator of molybdate metabolism, LysR family Bcen_0555 76 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 107023835 Common - Sel1-like repeat Bcen_2288 62 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 107022420 Pathogen - hypothetical protein Bcen_0865 1 None None None 107021722 Common - GntR-like Bcen_0162 125 COG2186 FadR, Transcriptional regulators Transcription 107023889 Pathogen - hypothetical protein Bcen_2342 1 None None None 107024314 Common rplA 50S ribosomal protein L1 Bcen_2770 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 107021626 Common - hypothetical protein Bcen_0065 8 None None None 107022874 Common - Rieske (2Fe-2S) region Bcen_1322 60 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 107023809 Common - L-carnitine dehydratase/bile acid-inducible protein F Bcen_2262 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 107023320 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Bcen_1771 112 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107023391 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Bcen_1842 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 107021883 Pathogen - hypothetical protein Bcen_0325 1 None None None 107022010 Common - hypothetical protein Bcen_0452 3 None None None 107021676 Common - 17 kDa surface antigen Bcen_0116 8 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 107024407 Common - 30S ribosomal protein S21 Bcen_2865 76 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 107023450 Common ileS isoleucyl-tRNA synthetase Bcen_1901 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107021768 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Bcen_0208 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 107022102 Common - peptidase C26 Bcen_0545 125 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 107022473 Common - hypothetical protein Bcen_0918 22 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 107024013 Common - lipid A biosynthesis lauroyl acyltransferase Bcen_2468 88 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 107023328 Common - major facilitator superfamily MFS_1 Bcen_1779 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107024076 Common - transcriptional regulator, GntR family Bcen_2531 137 COG1802 GntR, Transcriptional regulators Transcription 107022808 Common - periplasmic binding protein/LacI transcriptional regulator Bcen_1256 20 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107021595 Common fliP flagellar biosynthesis protein FliP Bcen_0033 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 107023031 Common - transcriptional regulator, winged helix family Bcen_1479 88 COG3903 COG3903, Predicted ATPase General function prediction only 107023907 Pathogen - hypothetical protein Bcen_2361 1 None None None 107024101 Common - Integrase, catalytic region Bcen_2556 81 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021774 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Bcen_0214 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 107023692 Common - acyl carrier protein Bcen_2145 42 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107024422 Common - hypothetical protein Bcen_2880 2 None None None 107024021 Common - transcriptional regulators, TraR/DksA family Bcen_2476 145 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 107023104 Common - beta-ketothiolase Bcen_1553 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 107021780 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Bcen_0220 101 COG0388 COG0388, Predicted amidohydrolase General function prediction only 107021577 Common - putative general secretion pathway protein J Bcen_0015 3 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 107023991 Common - hypothetical protein Bcen_2446 13 None None None 107022629 Common aat leucyl/phenylalanyl-tRNA--protein transferase Bcen_1076 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 107023873 Common - 2-oxoacid ferredoxin oxidoreductase Bcen_2326 94 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 107022762 Pathogen - hypothetical protein Bcen_1209 1 None None None 107023898 Common - 2-nitropropane dioxygenase, NPD Bcen_2351 99 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 107021740 Common - Carbohydrate kinase, thermoresistant glucokinase Bcen_0180 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 107022919 Common - hypothetical protein Bcen_1367 29 COG3652 COG3652, Predicted outer membrane protein Function unknown 107023718 Common - sodium/hydrogen exchanger Bcen_2171 196 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 107022900 Common katE hydroperoxidase II Bcen_1348 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 107021729 Common - MotA/TolQ/ExbB proton channel Bcen_0169 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 107023667 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Bcen_2120 215 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 107023933 Common - FAD dependent oxidoreductase Bcen_2387 116 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107021644 Common - Redoxin Bcen_0083 82 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 107023603 Pathogen - copper resistance D Bcen_2056 1 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 162218050 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Bcen_2412 47 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 107023139 Common - methionine sulfoxide reductase A Bcen_1588 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 107023088 Common - dihydrodipicolinate synthase Bcen_1537 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 107023624 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Bcen_2077 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 107024124 Common - protein-disulfide isomerase-like Bcen_2579 69 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 107023142 Common deoA thymidine phosphorylase Bcen_1591 119 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 107021963 Common - glycosyl transferase, family 2 Bcen_0405 78 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107022157 Common mogA molybdenum cofactor biosynthesis protein Bcen_0600 171 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 107023402 Pathogen - hypothetical protein Bcen_1853 1 None None None 107023577 Common - glycosyl hydrolase, BNR repeat Bcen_2030 5 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 107022358 Common - hypothetical protein Bcen_0802 38 COG1742 COG1742, Uncharacterized conserved protein Function unknown 107024354 Common - D-galactonate transporter Bcen_2810 132 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107023865 Common - 8-amino-7-oxononanoate synthase Bcen_2318 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 107022258 Common - Arginine N-succinyltransferase Bcen_0702 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 107023963 Common - glutathione S-transferase-like Bcen_2418 83 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107024174 Common - Rhs element Vgr protein Bcen_2630 50 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 107023385 Common - cobalbumin biosynthesis enzyme Bcen_1836 127 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 107023663 Common - thiopurine S-methyltransferase Bcen_2116 18 None None None 107022712 Common - Cyclic peptide transporter Bcen_1159 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 107023582 Common - hypothetical protein Bcen_2035 45 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 107022227 Common - putative GAF sensor protein Bcen_0671 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 107023116 Common - major facilitator superfamily MFS_1 Bcen_1565 147 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107023645 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Bcen_2098 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 107021916 Common - peptidase S10, serine carboxypeptidase Bcen_0358 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 107023882 Common - transcriptional regulator, LysR family Bcen_2335 157 COG0583 LysR, Transcriptional regulator Transcription 107022281 Common - transcriptional regulator, BadM/Rrf2 family Bcen_0725 50 COG1959 COG1959, Predicted transcriptional regulator Transcription 107023627 Common - transcriptional regulator, LysR family Bcen_2080 113 COG0583 LysR, Transcriptional regulator Transcription 107022642 Common - phage-related integrase Bcen_1089 3 None None None 107023860 Common - Carbonate dehydratase Bcen_2313 143 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 107023416 Common - transcriptional regulator, LysR family Bcen_1867 181 COG0583 LysR, Transcriptional regulator Transcription 107022779 Common - transposase Tn3 Bcen_1226 54 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 107022189 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Bcen_0633 150 COG0546 Gph, Predicted phosphatases General function prediction only 107022614 Common - periplasmic binding protein/LacI transcriptional regulator Bcen_1061 88 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107023886 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Bcen_2339 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 107024280 Common rpsM 30S ribosomal protein S13 Bcen_2736 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 107022042 Pathogen - hypothetical protein Bcen_0484 1 None None None 107023033 Common - beta-lactamase-like Bcen_1481 59 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 107021778 Common - NAD(P) transhydrogenase, beta subunit Bcen_0218 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 107022627 Common - dihydroorotate dehydrogenase 2 Bcen_1074 168 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 107022427 Common - MltA-interacting MipA Bcen_0872 23 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 107021865 Common - YiaAB two helix Bcen_0307 12 COG4682 COG4682, Predicted membrane protein Function unknown 107021789 Common - Paraquat-inducible protein A Bcen_0229 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 107022559 Common - uncharacterized lipoprotein-like Bcen_1004 26 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 107022106 Common - TPR repeat Bcen_0549 154 COG0457 NrfG, FOG: TPR repeat General function prediction only 107023061 Common - putative secreted protein Bcen_1509 45 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107021743 Common - adenylosuccinate lyase Bcen_0183 233 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 107022754 Common - transposase, mutator type Bcen_1201 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023223 Common - osmosensitive K+ channel signal transduction histidine kinase Bcen_1673 217 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 107023476 Common - 2-dehydropantoate 2-reductase Bcen_1927 32 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 107023511 Common - selenium-binding protein Bcen_1962 18 COG5276 COG5276, Uncharacterized conserved protein Function unknown 107024375 Common - Amidase Bcen_2832 213 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 107022272 Common - transposase IS116/IS110/IS902 Bcen_0716 26 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021656 Common - type II secretion system protein E Bcen_0096 191 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 107022034 Common nusB transcription antitermination protein NusB Bcen_0476 169 COG0781 NusB, Transcription termination factor Transcription 107022446 Common - phospholipid/glycerol acyltransferase Bcen_0891 38 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 107023150 Common - Acetyl-CoA C-acetyltransferase Bcen_1599 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 107021928 Pathogen - hypothetical protein Bcen_0370 1 None None None 107022436 Common - transcriptional regulator, LysR family Bcen_0881 184 COG0583 LysR, Transcriptional regulator Transcription 107022630 Common - NUDIX hydrolase Bcen_1077 38 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 107021737 Common - phosphogluconate dehydratase Bcen_0177 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 107024337 Common - hypothetical protein Bcen_2793 2 None None None 107022790 Common - porin, Gram-negative type Bcen_1237 23 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107022622 Common - ribose-5-phosphate isomerase A Bcen_1069 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 107021591 Common fliL flagellar basal body-associated protein FliL Bcen_0029 40 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 107023482 Common - tetraacyldisaccharide 4'-kinase Bcen_1933 115 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 107024140 Common prfA peptide chain release factor 1 Bcen_2595 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 107021859 Common - 8-amino-7-oxononanoate synthase Bcen_0301 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 107022403 Common - putative outer membrane protein Bcen_0848 5 None None None 107021611 Pathogen - hypothetical protein Bcen_0049 1 None None None 107022541 Common - Twin-arginine translocation pathway signal Bcen_0986 99 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 107022799 Common - short-chain dehydrogenase/reductase SDR Bcen_1246 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107024396 Common motB flagellar motor protein MotB Bcen_2853 99 COG1360 MotB, Flagellar motor protein Cell motility and secretion 107024231 Common - ABC transporter related Bcen_2687 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 107024290 Common rpsN 30S ribosomal protein S14 Bcen_2746 208 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 107022195 Common rpmF 50S ribosomal protein L32 Bcen_0639 91 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 107021567 Common - histone-like DNA-binding protein Bcen_0005 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 107023044 Common - alpha/beta hydrolase fold Bcen_1492 163 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107024152 Common - hypothetical protein Bcen_2608 33 None None None 107023744 Common - hypothetical protein Bcen_2197 41 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 107022578 Common - secretion protein HlyD Bcen_1024 140 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 107022912 Common - transcriptional regulator, LysR family Bcen_1360 176 COG0583 LysR, Transcriptional regulator Transcription 107023406 Common - permease YjgP/YjgQ Bcen_1857 108 COG0795 COG0795, Predicted permeases General function prediction only 107023726 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Bcen_2179 139 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 107024155 Common - hypothetical protein Bcen_2611 15 COG5608 COG5608, Conserved secreted protein Function unknown 107022201 Common - 3-oxoacyl-(acyl carrier protein) synthase II Bcen_0645 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107022020 Common - transcriptional regulator, DeoR family Bcen_0462 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 107023716 Common - Lysine exporter protein (LYSE/YGGA) Bcen_2169 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 107022391 Common - peptidase M23B Bcen_0836 168 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 107023459 Common - multicopper oxidase, type 3 Bcen_1910 127 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 107022299 Common - cytochrome B561 Bcen_0743 33 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 107022070 Common - General substrate transporter Bcen_0512 150 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107022452 Common - cellulose synthase regulator protein Bcen_0897 22 None None None 107023649 Common - ABC transporter related Bcen_2102 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 107023022 Common - cytochrome c, class I Bcen_1470 54 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 107021910 Common - transcriptional regulator, LysR family Bcen_0352 92 COG0583 LysR, Transcriptional regulator Transcription 107021984 Common - hypothetical protein Bcen_0426 20 None None None 107023015 Common - alpha/beta hydrolase fold Bcen_1463 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107024351 Common - hypothetical protein Bcen_2807 20 COG3644 COG3644, Uncharacterized protein conserved in bacteria Function unknown 107021995 Common - hypothetical protein Bcen_0437 6 None None None 107022386 Pathogen - hypothetical protein Bcen_0831 1 None None None 107022075 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Bcen_0517 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 107023976 Common - extracellular solute-binding protein, family 5 Bcen_2431 202 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 107023050 Common - extracellular solute-binding protein, family 3 Bcen_1498 163 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107023927 Common - putative aminotransferase Bcen_2381 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 107022246 Common - luciferase-like Bcen_0690 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 107023441 Common rpmG 50S ribosomal protein L33 Bcen_1892 134 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 107023307 Pathogen - hypothetical protein Bcen_1758 1 None None None 107024144 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Bcen_2599 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 107022260 Common - aldehyde dehydrogenase Bcen_0704 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107022205 Common - sigma E regulatory protein, MucB/RseB Bcen_0649 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 107022864 Common - Alcohol dehydrogenase, zinc-binding Bcen_1312 165 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 107023237 Common - hypothetical protein Bcen_1687 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 107022047 Common - extracellular solute-binding protein, family 1 Bcen_0489 70 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107024214 Common tatB sec-independent translocase Bcen_2670 23 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 107023793 Common - Phosphoenolpyruvate-protein phosphotransferase Bcen_2246 232 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 107023279 Pathogen - hypothetical protein Bcen_1730 1 None None None 107021876 Common - TonB-like Bcen_0318 5 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 107023376 Common - protein of unknown function DUF490 Bcen_1827 102 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 107024510 Common - inner-membrane translocator Bcen_2968 94 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 107022159 Common - peptidase U62, modulator of DNA gyrase Bcen_0602 154 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 107022200 Common acpP acyl carrier protein Bcen_0644 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107023371 Common dcd deoxycytidine triphosphate deaminase Bcen_1822 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 107022254 Common - ABC transporter related Bcen_0698 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 107023378 Common - hypothetical protein Bcen_1829 15 None None None 107021661 Common obgE GTPase ObgE Bcen_0101 236 COG0536 Obg, Predicted GTPase General function prediction only 107021875 Common tolB translocation protein TolB Bcen_0317 154 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 107023093 Common - transcriptional regulator, DeoR family Bcen_1542 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 107024096 Common - ribonuclease P protein component Bcen_2551 42 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 107022546 Common - (p)ppGpp synthetase I, SpoT/RelA Bcen_0991 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 107021757 Common rpsI 30S ribosomal protein S9 Bcen_0197 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 107021752 Common - dihydroorotase Bcen_0192 88 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 107022152 Common - adenosylcobinamide-phosphate synthase Bcen_0595 37 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 107022606 Common - hypothetical protein Bcen_1053 2 None None None 107024454 Pathogen - hypothetical protein Bcen_2912 1 None None None 107023205 Common - RNA polymerase factor sigma-70 Bcen_1655 59 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107021687 Common - UDP-N-acetylmuramate Bcen_0127 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 107024221 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Bcen_2677 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 107021670 Common - hypothetical protein Bcen_0110 10 None None None 107023606 Common - DEAD/DEAH box helicase-like Bcen_2059 228 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 107022566 Common - hypothetical protein Bcen_1012 41 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021645 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Bcen_0084 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 107023495 Pathogen - AMP-binding enzyme domain protein Bcen_1946 1 None None None 107022160 Common - Dihydrofolate reductase Bcen_0603 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 107024448 Common - hypothetical protein Bcen_2906 11 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 107024196 Common - hypothetical protein Bcen_2652 10 None None None 107023635 Common - Tetratricopeptide TPR_2 Bcen_2088 34 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 107022571 Pathogen - hypothetical protein Bcen_1017 1 None None None 107023187 Common - NADH dehydrogenase subunit B Bcen_1636 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 107022959 Common - Oxidoreductase alpha (molybdopterin) subunit Bcen_1407 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 107022509 Common - two component transcriptional regulator, winged helix family Bcen_0954 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107023311 Common - Resolvase-like Bcen_1762 137 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 107021795 Common secF preprotein translocase subunit SecF Bcen_0235 205 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 107024209 Common - cytochrome b/b6-like Bcen_2665 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 107024081 Common - glutamate--cysteine ligase Bcen_2536 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 107024500 Common - Citrate transporter Bcen_2958 77 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 107023920 Common - hypothetical protein Bcen_2374 19 COG3794 PetE, Plastocyanin Energy production and conversion 107023272 Common - benzoate transporter Bcen_1722 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 107021587 Common - PilT protein-like Bcen_0025 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 107021580 Common - General secretion pathway M protein Bcen_0018 5 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 107024299 Common rpsS 30S ribosomal protein S19 Bcen_2755 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 107023333 Common - hypothetical protein Bcen_1784 2 None None None 107022476 Common - hypothetical protein Bcen_0921 4 None None None 107023935 Common - hypothetical protein Bcen_2390 13 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 107023855 Common - short chain dehydrogenase Bcen_2308 211 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107023079 Common - major facilitator superfamily MFS_1 Bcen_1528 83 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022970 Common - ATPase AAA-2 Bcen_1418 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 107022169 Common - hypothetical protein Bcen_0613 39 COG2501 COG2501, Uncharacterized conserved protein Function unknown 107024318 Common - elongation factor Tu Bcen_2774 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 107024400 Common - glycosyl transferase, group 1 Bcen_2857 165 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107024333 Common pyrE orotate phosphoribosyltransferase Bcen_2789 105 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 107023095 Common - Phytanoyl-CoA dioxygenase Bcen_1544 27 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 107021840 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase Bcen_0280 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 107023038 Common - protein of unknown function DUF1427 Bcen_1486 16 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 107024326 Common - transcriptional regulator, TetR family Bcen_2782 79 COG1309 AcrR, Transcriptional regulator Transcription 107022691 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1138 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107021703 Common pyrF orotidine 5'-phosphate decarboxylase Bcen_0143 83 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 107021665 Common - prolyl-tRNA synthetase Bcen_0105 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107023007 Common - transcriptional regulator, TrmB Bcen_1455 29 COG1378 COG1378, Predicted transcriptional regulators Transcription 107022494 Common - Xylose isomerase-like TIM barrel Bcen_0939 65 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 107022464 Common - sodium/hydrogen exchanger Bcen_0909 136 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 107023983 Common - Endonuclease/exonuclease/phosphatase Bcen_2438 37 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 107022348 Common - phosphoribosyl-dephospho-CoA transferase Bcen_0792 10 None None None 107023522 Common - Mannitol dehydrogenase-like Bcen_1975 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 107022998 Common - hypothetical protein Bcen_1446 6 None None None 107022500 Common - Xylose isomerase-like TIM barrel Bcen_0945 24 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 107022361 Common - Methyltransferase type 11 Bcen_0805 85 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 107022841 Common - hypothetical protein Bcen_1289 17 None None None 107022518 Common - methyl-accepting chemotaxis sensory transducer Bcen_0963 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 107022416 Common - Alcohol dehydrogenase, zinc-binding Bcen_0861 183 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 107024481 Common - AMP-dependent synthetase and ligase Bcen_2939 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107023243 Common - membrane protein-like Bcen_1693 2 COG4129 COG4129, Predicted membrane protein Function unknown 107023610 Common - transcriptional regulator, DeoR family Bcen_2063 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 107022292 Common - hypothetical protein Bcen_0736 107 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 107023806 Common - C4-dicarboxylate transporter DctA Bcen_2259 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 107024066 Common - Phenylacetic acid degradation-related protein Bcen_2521 68 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 107022848 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_1296 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107023194 Common - ABC branched chain amino acid family transporter, periplasmic ligand binding protein Bcen_1643 63 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107022499 Common - inner-membrane translocator Bcen_0944 149 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 107023738 Common - histidinol-phosphate aminotransferase Bcen_2191 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 107023137 Common - Protein-methionine-S-oxide reductase Bcen_1586 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 107024198 Common - transposase IS116/IS110/IS902 Bcen_2654 22 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023252 Common - hypothetical protein Bcen_1702 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 107022081 Common greB transcription elongation factor GreB Bcen_0523 180 COG0782 GreA, Transcription elongation factor Transcription 107024307 Common - 30S ribosomal protein S7 Bcen_2763 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 107021624 Common - molybdopterin oxidoreductase Bcen_0063 182 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 107021979 Common ureC urease subunit alpha Bcen_0421 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 107023165 Common - glutathione S-transferase-like Bcen_1614 84 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107022885 Common - Glycogen debranching enzyme GlgX Bcen_1333 147 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 107023551 Common - protein of unknown function DUF427 Bcen_2004 47 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 107023318 Common - 4Fe-4S ferredoxin, iron-sulfur binding Bcen_1769 11 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 107024056 Common - Lysine exporter protein (LYSE/YGGA) Bcen_2511 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 107022749 Common cbiD cobalt-precorrin-6A synthase Bcen_1196 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 107022029 Pathogen - hypothetical protein Bcen_0471 1 None None None 107023697 Common - exporter-like Bcen_2150 23 COG4258 COG4258, Predicted exporter General function prediction only 107021732 Common - Rare lipoprotein B Bcen_0172 28 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 107024184 Common - Tetratricopeptide TPR_2 Bcen_2640 4 None None None 107022651 Pathogen - hypothetical protein Bcen_1098 1 None None None 107023503 Common - Pirin-like Bcen_1954 144 COG1741 COG1741, Pirin-related protein General function prediction only 107021631 Common - Cell division protein, FtsL -like Bcen_0070 2 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 107021803 Pathogen - hypothetical protein Bcen_0243 1 None None None 107023905 Common - N-acylglucosamine 2-epimerase Bcen_2359 46 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 107023280 Common - putative transcriptional regulator Bcen_1731 12 COG2413 COG2413, Predicted nucleotidyltransferase General function prediction only 107023757 Common - Glutamine-fructose-6-phosphate transaminase (isomerizing) Bcen_2210 233 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 107024253 Common ugpC glycerol-3-phosphate transporter ATP-binding subunit Bcen_2709 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 107024031 Common - Methionine biosynthesis MetW Bcen_2486 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 107022886 Common - Malto-oligosyltrehalose trehalohydrolase Bcen_1334 158 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 107023437 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Bcen_1888 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 107022722 Common - Peptidase M20D, amidohydrolase Bcen_1169 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 107022661 Common - aldo/keto reductase Bcen_1108 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 107024463 Common - Aldehyde dehydrogenase (NAD+) Bcen_2921 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107023529 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Bcen_1982 116 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 107023949 Common flgI flagellar basal body P-ring protein Bcen_2404 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 107023842 Common - Patatin Bcen_2295 42 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 107021571 Common - Type II secretion system gspE Bcen_0009 213 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 107022704 Common - hypothetical protein Bcen_1151 2 None None None 107023285 Common - transcriptional regulator, GntR family Bcen_1736 214 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 107023352 Common - transcriptional regulator, AraC family Bcen_1803 7 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107022635 Common - alkanesulfonate monooxygenase Bcen_1082 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 107023366 Common - transposase IS116/IS110/IS902 Bcen_1817 64 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 107022937 Common - Histidinol-phosphate phosphatase Bcen_1385 124 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 107023547 Common - transcriptional regulator, TetR family Bcen_2000 127 COG1309 AcrR, Transcriptional regulator Transcription 107022534 Common - Electron-transferring-flavoprotein dehydrogenase Bcen_0979 112 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 107023283 Common - Chorismate lyase Bcen_1734 39 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 107021633 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Bcen_0072 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 107023533 Common - Tagatose-6-phosphate kinase Bcen_1986 32 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 107023461 Common - isocitrate dehydrogenase, NADP-dependent Bcen_1912 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 107023220 Common - small multidrug resistance protein Bcen_1670 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 107023338 Common - two component transcriptional regulator, winged helix family Bcen_1789 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107021951 Common - rhamnosyltransferase Bcen_0393 35 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107023753 Common - Beta-N-acetylhexosaminidase Bcen_2206 51 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 107024089 Pathogen - hypothetical protein Bcen_2544 1 None None None 107021847 Common - hypothetical protein Bcen_0289 17 None None None 107023826 Common - transposase, IS4 Bcen_2279 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 107024483 Common - Extracellular ligand-binding receptor Bcen_2941 142 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107022727 Common - uroporphyrin-III C-methyltransferase Bcen_1174 199 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 107022139 Common - Lipoprotein YaeC Bcen_0582 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 107024296 Common rplP 50S ribosomal protein L16 Bcen_2752 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 107022666 Common - permease Bcen_1113 87 COG0701 COG0701, Predicted permeases General function prediction only 107022329 Common - histone deacetylase superfamily Bcen_0773 157 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 107024412 Common - DegT/DnrJ/EryC1/StrS aminotransferase Bcen_2870 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 107022053 Common - thioredoxin reductase Bcen_0495 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 107024352 Common - glutathione S-transferase-like Bcen_2808 49 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107024043 Common - Rod shape-determining protein MreD Bcen_2498 55 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 107022280 Pathogen - hypothetical protein Bcen_0724 1 None None None 107021608 Pathogen - hypothetical protein Bcen_0046 1 None None None 107024268 Common - putative sulfite oxidase subunit YedY Bcen_2724 124 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 107021839 Common - transcriptional regulator, TetR family Bcen_0279 49 COG1309 AcrR, Transcriptional regulator Transcription 107023680 Common - major facilitator superfamily MFS_1 Bcen_2133 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023723 Common - ABC transporter related Bcen_2176 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 107024287 Common rplR 50S ribosomal protein L18 Bcen_2743 217 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 107022175 Common - CreA Bcen_0619 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 107023660 Common aspS aspartyl-tRNA synthetase Bcen_2113 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107023277 Common - spermidine synthase-like Bcen_1727 42 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 107021750 Common - Outer membrane autotransporter barrel Bcen_0190 76 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107021600 Common - binding-protein-dependent transport systems inner membrane component Bcen_0038 156 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 107022825 Common - CopG-like DNA-binding Bcen_1273 9 None None None 107022736 Common - Low molecular weight phosphotyrosine protein phosphatase Bcen_1183 20 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 107022027 Common - protein of unknown function YGGT Bcen_0469 104 COG0762 COG0762, Predicted integral membrane protein Function unknown 107021685 Common - transposase, IS605 OrfB Bcen_0125 67 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023355 Common - Aldehyde dehydrogenase (NAD+) Bcen_1806 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107022907 Pathogen - hypothetical protein Bcen_1355 1 COG5373 COG5373, Predicted membrane protein Function unknown 107022267 Common - Redoxin Bcen_0711 216 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 107022221 Pathogen - hypothetical protein Bcen_0665 1 None None None 107022977 Common - Molybdenum cofactor biosynthesis protein A Bcen_1425 194 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 107023918 Common - hypothetical protein Bcen_2372 2 None None None 107023702 Pathogen - hypothetical protein Bcen_2155 2 None None None 107024247 Common - amino acid carrier protein Bcen_2703 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 107021720 Common - major facilitator superfamily MFS_1 Bcen_0160 107 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023428 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase Bcen_1879 166 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 107024068 Common - protein of unknown function DUF1470 Bcen_2523 13 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 107021797 Common yajC preprotein translocase subunit YajC Bcen_0237 180 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 107024512 Common - ABC branched-chain amino acid family transporter, periplasmic ligand binding protein Bcen_2970 96 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107022658 Common - phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases like enzyme Bcen_1105 45 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 107024004 Common - predicted kinase Bcen_2459 52 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 107022842 Common - protein of unknown function DUF305 Bcen_1290 38 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 107022124 Common - cytidylate kinase Bcen_0567 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 107022703 Pathogen - hypothetical protein Bcen_1150 1 None None None 107023140 Common - Rieske (2Fe-2S) region Bcen_1589 86 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 107023564 Common pgk phosphoglycerate kinase Bcen_2017 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 107023659 Common ntpA dATP pyrophosphohydrolase Bcen_2112 37 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 107022963 Common - Rhs element Vgr protein Bcen_1411 50 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 107022234 Common - HAD-superfamily hydrolase subfamily IIB Bcen_0678 83 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 107022983 Common - transcriptional regulator, LysR family Bcen_1431 131 COG0583 LysR, Transcriptional regulator Transcription 107022305 Common - metallophosphoesterase Bcen_0749 96 COG1409 Icc, Predicted phosphohydrolases General function prediction only 107024114 Common - ribulose-phosphate 3-epimerase Bcen_2569 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 107023300 Common - Rubredoxin-type Fe(Cys)4 protein Bcen_1751 115 COG1773 COG1773, Rubredoxin Energy production and conversion 107021938 Common - Rubredoxin-type Fe(Cys)4 protein Bcen_0380 113 COG1773 COG1773, Rubredoxin Energy production and conversion 107023787 Common - preprotein translocase subunit SecB Bcen_2240 109 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 107023556 Common - sterol desaturase-like Bcen_2009 75 COG3000 ERG3, Sterol desaturase Lipid metabolism 107023732 Common - Tetratricopeptide TPR_2 Bcen_2185 141 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 107022503 Common - oxidoreductase-like Bcen_0948 155 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 107022941 Common - transport-associated Bcen_1389 13 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 162218054 Common pheS phenylalanyl-tRNA synthetase subunit alpha Bcen_0997 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 107022322 Common - Male sterility-like Bcen_0766 59 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107024402 Common - aquaporin Z Bcen_2859 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 107023494 Common - hypothetical protein Bcen_1945 158 COG0344 COG0344, Predicted membrane protein Function unknown 107022897 Common - sodium/hydrogen exchanger Bcen_1345 19 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 107023081 Common - short-chain dehydrogenase/reductase SDR Bcen_1530 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023246 Common - glycosyl transferase, family 2 Bcen_1696 85 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 107023675 Common - N-acyl-D-amino-acid deacylase Bcen_2128 62 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 107023947 Common - YcgR Bcen_2402 22 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 107022584 Common - AFG1-like ATPase Bcen_1031 104 COG1485 COG1485, Predicted ATPase General function prediction only 107022612 Common - sulphate transporter Bcen_1059 159 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 107023387 Common - hypothetical protein Bcen_1838 147 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 107023400 Common - dihydroxy-acid dehydratase Bcen_1851 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 107023896 Common - transcriptional regulator, AsnC family Bcen_2349 154 COG1522 Lrp, Transcriptional regulators Transcription 107022710 Common - ferric iron reductase Bcen_1157 19 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 107021782 Common - glyoxalase/bleomycin resistance protein/dioxygenase Bcen_0222 29 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 107023152 Common - AMP-dependent synthetase and ligase Bcen_1601 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 107022256 Common - transposase, mutator type Bcen_0700 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023013 Common - DoxX Bcen_1461 6 COG2259 COG2259, Predicted membrane protein Function unknown 107024165 Common - hypothetical protein Bcen_2621 8 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 107023256 Pathogen - hypothetical protein Bcen_1706 2 None None None 107023625 Common - transcriptional regulator, XRE family Bcen_2078 98 COG1396 HipB, Predicted transcriptional regulators Transcription 107022448 Common - alpha/beta hydrolase fold Bcen_0893 72 COG2267 PldB, Lysophospholipase Lipid metabolism 107024078 Common - transcriptional regulator, LysR family Bcen_2533 190 COG0583 LysR, Transcriptional regulator Transcription 107022826 Common - spermidine synthase-like protein Bcen_1274 47 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 107024471 Common - transcriptional regulator, AraC family Bcen_2929 110 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 107022753 Common - transcriptional regulator, MarR family Bcen_1200 71 COG1846 MarR, Transcriptional regulators Transcription 107024122 Common - (Acyl-carrier protein) phosphodiesterase Bcen_2577 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 107023326 Pathogen - hypothetical protein Bcen_1777 1 None None None 107021654 Common - Prepilin peptidase Bcen_0094 122 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 107024060 Common - Thioredoxin domain Bcen_2515 17 None None None 107023516 Common - kynureninase Bcen_1967 89 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 107024200 Common - hypothetical protein Bcen_2656 4 None None None 107022351 Common - hypothetical protein Bcen_0795 7 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 107021727 Common - SmpA/OmlA Bcen_0167 63 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 107022337 Common - heat shock protein Hsp20 Bcen_0781 70 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 107023562 Common - fructose-1,6-bisphosphate aldolase Bcen_2015 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 107022269 Common - transposase, IS605 OrfB Bcen_0713 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 107021699 Common araG L-arabinose transporter ATP-binding protein Bcen_0139 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 107023579 Common - hypothetical protein Bcen_2032 2 None None None 107022930 Common - two component, sigma54 specific, transcriptional regulator, Fis family Bcen_1378 176 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107023995 Common fliF flagellar MS-ring protein Bcen_2450 127 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 107021761 Common - D-tyrosyl-tRNA deacylase Bcen_0201 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 107023396 Common - protein of unknown function DUF589 Bcen_1847 93 COG2947 COG2947, Uncharacterized conserved protein Function unknown 107022646 Common - C-5 cytosine-specific DNA methylase Bcen_1093 5 None None None 107023622 Common - Myo-inositol 2-dehydrogenase Bcen_2075 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 107022287 Pathogen - hypothetical protein Bcen_0731 1 None None None 107022594 Common - type II and III secretion system protein Bcen_1041 141 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 107024344 Common - protein of unknown function DUF82 Bcen_2800 29 COG1656 COG1656, Uncharacterized conserved protein Function unknown 107023978 Common - Twin-arginine translocation pathway signal Bcen_2433 8 None None None 107022098 Common - adenosine deaminase Bcen_0541 131 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 107024366 Common - hypothetical protein Bcen_2822 12 None None None 107023713 Common - putative transporter Bcen_2166 22 COG0628 PerM, Predicted permease General function prediction only 107023993 Common - flagellar protein FliS Bcen_2448 76 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 107022640 Pathogen - hypothetical protein Bcen_1087 1 None None None 107021933 Common - hypothetical protein Bcen_0375 2 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 107021903 Common - transcriptional regulator, AraC family Bcen_0345 84 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107023218 Common - protein of unknown function DUF214 Bcen_1668 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 107022647 Common - hypothetical protein Bcen_1094 6 None None None 107023661 Common - protein of unknown function DUF502 Bcen_2114 85 COG2928 COG2928, Uncharacterized conserved protein Function unknown 107021896 Common - fumarylacetoacetase Bcen_0338 49 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 107022380 Common - two component transcriptional regulator, winged helix family Bcen_0824 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107022760 Common - binding-protein-dependent transport systems inner membrane component Bcen_1207 169 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 107023580 Pathogen - TonB-like Bcen_2033 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 107023871 Common - diguanylate phosphodiesterase Bcen_2324 158 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 107022786 Common - Propeptide, peptidase M4 and M36 Bcen_1233 43 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 107023114 Common - putative integral membrane sensor protein Bcen_1563 169 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 107023070 Common - hypothetical protein Bcen_1518 20 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 107022244 Common - pyridoxal kinase Bcen_0688 64 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 107023665 Common - protein of unknown function DUF1243 Bcen_2118 17 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 107023102 Common - transcriptional regulator, TetR family Bcen_1551 42 COG1309 AcrR, Transcriptional regulator Transcription 107023796 Common - glutathione synthetase Bcen_2249 123 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 107021776 Common - alanine dehydrogenase/PNT-like Bcen_0216 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 107022719 Common - hypothetical protein Bcen_1166 43 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 107023837 Common - biotin--protein ligase Bcen_2290 178 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 107023294 Common - transcriptional regulator, LysR family Bcen_1745 153 COG0583 LysR, Transcriptional regulator Transcription 107022086 Common - chorismate mutase Bcen_0529 13 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 107022830 Common - GCN5-related N-acetyltransferase Bcen_1278 30 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 107023849 Common - 5-methyltetrahydrofolate--homocysteine S-methyltransferase Bcen_2302 164 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 107022015 Common - major facilitator superfamily MFS_1 Bcen_0457 170 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 107022187 Common - ribonuclease, Rne/Rng family Bcen_0631 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 107024381 Common flhF flagellar biosynthesis regulator FlhF Bcen_2838 246 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 107022975 Common - formate dehydrogenase family accessory protein FdhD Bcen_1423 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 107022146 Common - glucose/sorbosone dehydrogenase-like Bcen_0589 80 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 107023193 Common rpsO 30S ribosomal protein S15 Bcen_1642 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 107024478 Common - putative aminotransferase Bcen_2936 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 107024497 Common - F0F1 ATP synthase subunit A Bcen_2955 183 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 107022961 Common - Sel1-like repeat Bcen_1409 62 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 107023592 Common - transcriptional regulator, LysR family Bcen_2045 168 COG0583 LysR, Transcriptional regulator Transcription 107021885 Common - membrane protein Bcen_0327 8 COG5393 COG5393, Predicted membrane protein Function unknown 107022129 Common - UDP-glucose 6-dehydrogenase Bcen_0572 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 107023807 Common actP acetate permease Bcen_2260 159 COG4147 DhlC, Predicted symporter General function prediction only 107022524 Pathogen - hypothetical protein Bcen_0969 1 None None None 107022680 Common - ABC transporter related Bcen_1127 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 107023655 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Bcen_2108 163 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 107022554 Common ihfA integration host factor subunit alpha Bcen_0999 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 107022837 Common - NUDIX hydrolase Bcen_1285 32 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 107024391 Common - MCP methyltransferase, CheR-type Bcen_2848 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 107023483 Common - protein of unknown function DUF343 Bcen_1934 108 COG2835 COG2835, Uncharacterized conserved protein Function unknown 107022806 Common - transcriptional regulator, AraC family Bcen_1254 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023046 Pathogen - hypothetical protein Bcen_1494 1 None None None 107021579 Common - General secretion pathway L Bcen_0017 9 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 107022111 Common - NADH-ubiquinone oxidoreductase 24 kD subunit-like Bcen_0554 141 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 107022687 Common - hypothetical protein Bcen_1134 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 107023922 Common - Aldehyde dehydrogenase (NAD+) Bcen_2376 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107022213 Common - pyridoxal phosphate biosynthetic protein PdxJ Bcen_0657 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 107023407 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Bcen_1858 52 COG2138 COG2138, Uncharacterized conserved protein Function unknown 107024301 Common rplW 50S ribosomal protein L23 Bcen_2757 212 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 107023693 Common - membrane protein-like Bcen_2146 17 COG4648 COG4648, Predicted membrane protein Function unknown 107024409 Common - flagellar hook-associated 2-like Bcen_2867 96 COG1345 FliD, Flagellar capping protein Cell motility and secretion 107024423 Common - hypothetical protein Bcen_2881 6 None None None 107021966 Common - polysaccharide biosynthesis protein CapD Bcen_0408 162 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107022366 Common - leucine export protein LeuE Bcen_0810 124 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 107023106 Common - acyl-CoA dehydrogenase-like Bcen_1555 155 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107024461 Common - transcriptional regulator, AraC family Bcen_2919 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107021808 Common glcF glycolate oxidase iron-sulfur subunit Bcen_0248 174 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 107021589 Common - LrgA Bcen_0027 22 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 107022620 Common - RNA methyltransferase TrmH, group 3 Bcen_1067 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 107023929 Common - spermidine/putrescine ABC transporter ATP-binding subunit Bcen_2383 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 107023954 Common flgD flagellar basal body rod modification protein Bcen_2409 88 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 107021632 Common - Peptidoglycan glycosyltransferase Bcen_0071 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 107022522 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_0967 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107024053 Common - hypothetical protein Bcen_2508 25 None None None 107022672 Pathogen - hypothetical protein Bcen_1119 1 None None None 107021716 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Bcen_0156 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 107023982 Pathogen - hypothetical protein Bcen_2437 1 None None None 107021614 Common - hypothetical protein Bcen_0052 4 None None None 107021583 Pathogen - hypothetical protein Bcen_0021 1 None None None 107023486 Common - hypothetical protein Bcen_1937 61 COG2912 COG2912, Uncharacterized conserved protein Function unknown 107022007 Pathogen - hypothetical protein Bcen_0449 1 None None None 107024256 Common - glycerol-3-phosphate transporter periplasmic binding protein Bcen_2712 95 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107022515 Common - UvrD/REP helicase Bcen_0960 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 107023974 Common - binding-protein-dependent transport systems inner membrane component Bcen_2429 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 107022028 Common - NADP oxidoreductase, coenzyme F420-dependent Bcen_0470 49 COG5495 COG5495, Uncharacterized conserved protein Function unknown 107023611 Common - hypothetical protein Bcen_2064 2 None None None 107021681 Common - acetyl-CoA carboxylase biotin carboxylase subunit Bcen_0121 231 COG0439 AccC, Biotin carboxylase Lipid metabolism 107023852 Common argS arginyl-tRNA synthetase Bcen_2305 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107024279 Common - 30S ribosomal protein S11 Bcen_2735 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 107022340 Pathogen - hypothetical protein Bcen_0784 1 None None None 107022083 Pathogen - hypothetical protein Bcen_0525 1 None None None 107023295 Common - integral membrane protein-like Bcen_1746 15 COG5615 COG5615, Predicted integral membrane protein Function unknown 107024275 Common - CutA1 divalent ion tolerance protein Bcen_2731 37 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 107021627 Common - porin, Gram-negative type Bcen_0066 25 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107021930 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Bcen_0372 74 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107022871 Common - Methyltransferase type 12 Bcen_1319 22 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 107022036 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Bcen_0478 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 107024118 Common trpD anthranilate phosphoribosyltransferase Bcen_2573 218 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 107022576 Common truB tRNA pseudouridine synthase B Bcen_1022 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 107023074 Common - inositol monophosphatase Bcen_1522 149 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 107022362 Common - Hydroxyacylglutathione hydrolase Bcen_0806 172 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 107021688 Common - protein of unknown function UPF0227 Bcen_0128 49 COG3150 COG3150, Predicted esterase General function prediction only 107023910 Common - short-chain dehydrogenase/reductase SDR Bcen_2364 5 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023128 Common - manganese/iron transporter, NRAMP family Bcen_1577 9 None None None 107023179 Common - NADH dehydrogenase subunit J Bcen_1628 77 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 107023448 Common purN phosphoribosylglycinamide formyltransferase Bcen_1899 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 107023395 Common - protein of unknown function DUF710 Bcen_1846 2 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 107024067 Common - hypothetical protein Bcen_2522 6 None None None 107023917 Pathogen - hypothetical protein Bcen_2371 1 None None None 107022609 Common - major facilitator superfamily MFS_1 Bcen_1056 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107021829 Common - Chaperone DnaJ Bcen_0269 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 107022251 Common - hypothetical protein Bcen_0695 12 None None None 107022162 Common - sigma54 specific transcriptional regulator, Fis family Bcen_0605 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107021771 Common - peptidase M24 Bcen_0211 204 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 107024001 Common - glucose-methanol-choline oxidoreductase Bcen_2456 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 107021638 Common murG N-acetylglucosaminyl transferase Bcen_0077 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 107024028 Common - Pyrimidine 5-nucleotidase Bcen_2483 47 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 107021878 Common - MotA/TolQ/ExbB proton channel Bcen_0320 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 107022432 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Bcen_0877 69 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 107022553 Common pheT phenylalanyl-tRNA synthetase subunit beta Bcen_0998 244 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 107023634 Common lnt apolipoprotein N-acyltransferase Bcen_2087 161 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 107021940 Common - hypothetical protein Bcen_0382 131 COG1678 COG1678, Putative transcriptional regulator Transcription 107024238 Common - thiamine-phosphate pyrophosphorylase Bcen_2694 152 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 107022915 Common - response regulator receiver protein Bcen_1363 113 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 107023648 Common - Nucleotidyl transferase Bcen_2101 200 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 107022374 Common - phosphoglucosamine mutase Bcen_0818 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 107023695 Common - acyltransferase-like Bcen_2148 38 COG4261 COG4261, Predicted acyltransferase General function prediction only 107021977 Common - Urease accessory protein UreF Bcen_0419 73 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 107024334 Common - YbhB and YbcL Bcen_2790 83 COG1881 COG1881, Phospholipid-binding protein General function prediction only 107024289 Common rpsH 30S ribosomal protein S8 Bcen_2745 245 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 107022741 Common - acyl-CoA dehydrogenase-like Bcen_1188 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107023345 Common - GCN5-related N-acetyltransferase Bcen_1796 65 COG0456 RimI, Acetyltransferases General function prediction only 107024083 Common - AlkA-like Bcen_2538 90 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 107021962 Pathogen - hypothetical protein Bcen_0404 1 None None None 107022328 Common - allantoate amidohydrolase Bcen_0772 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 107022091 Pathogen - hypothetical protein Bcen_0534 1 None None None 107021854 Common - Capsule polysaccharide biosynthesis Bcen_0296 31 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 107023204 Common - acetolactate synthase 3 catalytic subunit Bcen_1654 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 107022539 Common - 3-oxoacid CoA-transferase, subunit B Bcen_0984 94 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 107022816 Common - luciferase-like Bcen_1264 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 107022298 Common - thiamine biosynthesis protein ThiC Bcen_0742 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 107022411 Common - Alcohol dehydrogenase GroES-like Bcen_0856 135 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 107023132 Common - chaperonin Cpn10 Bcen_1581 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 107024226 Common hisD histidinol dehydrogenase Bcen_2682 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 107022815 Common - putative monooxygenase Bcen_1263 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 107024099 Common - DNA polymerase III subunit beta Bcen_2554 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 107023209 Common - metallophosphoesterase Bcen_1659 61 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 107023587 Common recX recombination regulator RecX Bcen_2040 72 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 107024181 Common - protein of unknown function DUF796 Bcen_2637 30 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 107022563 Common - protein of unknown function DUF218 Bcen_1009 52 COG1434 COG1434, Uncharacterized conserved protein Function unknown 107023261 Common - glycoside hydrolase 15-related Bcen_1711 71 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 107022953 Pathogen - membrane protein Bcen_1401 1 COG4803 COG4803, Predicted membrane protein Function unknown 107023005 Common - major facilitator superfamily MFS_1 Bcen_1453 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023162 Common - hypothetical protein Bcen_1611 75 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 107024061 Common - transposase IS116/IS110/IS902 Bcen_2516 22 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 107024446 Common - cytochrome c, class I Bcen_2904 44 COG3245 CycB, Cytochrome c5 Energy production and conversion 107022453 Common - endo-1,4-D-glucanase Bcen_0898 30 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 107022780 Common - phage integrase Bcen_1227 186 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 107022466 Common - isochorismatase hydrolase Bcen_0911 76 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 107023097 Common - protein of unknown function DUF815 Bcen_1546 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 107023686 Common - phospholipase D/Transphosphatidylase Bcen_2139 135 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 107021575 Common - General secretion pathway protein H Bcen_0013 3 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 107022679 Common - periplasmic binding protein/LacI transcriptional regulator Bcen_1126 119 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107023060 Common - Xylose isomerase-like TIM barrel Bcen_1508 32 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 107024012 Common - S-adenosylmethionine synthetase Bcen_2467 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 107022965 Common - tryptophanyl-tRNA synthetase II Bcen_1413 237 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107022492 Common - hypothetical protein Bcen_0937 15 COG4702 COG4702, Uncharacterized conserved protein Function unknown 107023317 Common - O-methyltransferase, family 3 Bcen_1768 64 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 107022066 Pathogen - hypothetical protein Bcen_0508 1 None None None 107022418 Common - NADH:flavin oxidoreductase/NADH oxidase Bcen_0863 198 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 107024516 Common - transcriptional regulator, LysR family Bcen_2974 173 COG0583 LysR, Transcriptional regulator Transcription 107021582 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_0020 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107023039 Common - isochorismatase hydrolase Bcen_1487 76 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 107023722 Common - OstA-like protein Bcen_2175 42 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 107023895 Common - protein of unknown function DUF6, transmembrane Bcen_2348 153 COG2962 RarD, Predicted permeases General function prediction only 107023012 Common - MscS Mechanosensitive ion channel Bcen_1460 139 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 107022383 Common - Ppx/GppA phosphatase Bcen_0827 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 107023217 Common - globin Bcen_1667 69 COG2346 COG2346, Truncated hemoglobins General function prediction only 107023768 Common - methyl-accepting chemotaxis sensory transducer Bcen_2221 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 107024146 Common - cold-shock DNA-binding domain protein Bcen_2602 177 COG1278 CspC, Cold shock proteins Transcription 107023421 Common - transcriptional regulator, LysR family Bcen_1872 117 COG0583 LysR, Transcriptional regulator Transcription 107022443 Pathogen - hypothetical protein Bcen_0888 1 None None None 107023024 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Bcen_1472 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 107022000 Pathogen - hypothetical protein Bcen_0442 3 None None None 107024265 Common cyaY frataxin-like protein Bcen_2721 41 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 107024522 Common - two component transcriptional regulator, winged helix family Bcen_2980 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107022883 Common - Trehalose synthase-like Bcen_1331 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 107023514 Common - transcriptional regulator, AsnC family Bcen_1965 159 COG1522 Lrp, Transcriptional regulators Transcription 107023457 Common clpS ATP-dependent Clp protease adaptor protein ClpS Bcen_1908 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 107022718 Common - folate-dependent phosphoribosylglycinamide formyltransferase PurN-like Bcen_1165 4 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 107022888 Common - Malto-oligosyltrehalose synthase Bcen_1336 71 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 107022902 Pathogen - protein of unknown function DUF1328 Bcen_1350 1 None None None 107022076 Common rph ribonuclease PH Bcen_0518 188 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 107021929 Common - Secreted repeat of unknown function Bcen_0371 35 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 107024191 Common - YD repeat Bcen_2647 62 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 107022625 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1072 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107022110 Common - NADH dehydrogenase (quinone) Bcen_0553 161 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 107023888 Common - (2Fe-2S)-binding Bcen_2341 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 107021696 Common - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Bcen_0136 124 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 107021724 Common - allantoicase Bcen_0164 15 COG4266 Alc, Allantoicase Nucleotide transport and metabolism 107023857 Common - ABC transporter related Bcen_2310 243 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 107022119 Common - hypothetical protein Bcen_0562 2 None None None 107022077 Common - hypothetical protein Bcen_0519 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 107023302 Pathogen - hypothetical protein Bcen_1753 1 None None None 107023309 Pathogen - hypothetical protein Bcen_1760 1 None None None 107024389 Common - chemotaxis-specific methylesterase Bcen_2846 213 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 107022368 Common greA transcription elongation factor GreA Bcen_0812 204 COG0782 GreA, Transcription elongation factor Transcription 107022477 Common - NUDIX hydrolase Bcen_0922 34 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 107023051 Common - amino acid permease-associated region Bcen_1499 178 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 107023473 Common - Drug resistance transporter EmrB/QacA subfamily Bcen_1924 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107024034 Common - transcriptional regulator, AraC family Bcen_2489 75 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107021895 Common - homogentisate 1,2-dioxygenase Bcen_0337 46 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 107023414 Common - transcriptional regulator CysB-like protein Bcen_1865 190 COG0583 LysR, Transcriptional regulator Transcription 107022604 Common - Host factor Hfq Bcen_1051 113 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 107022134 Common - Lytic murein transglycosylase B Bcen_0577 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 107023003 Common - short chain dehydrogenase Bcen_1451 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107024172 Pathogen - hypothetical protein Bcen_2628 1 None None None 107021914 Common - transport-associated Bcen_0356 4 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 107024105 Common - putative insertion element protein Bcen_2560 48 None None None 107024509 Pathogen - hypothetical protein Bcen_2967 1 None None None 107022040 Common - glutamate-1-semialdehyde 2,1-aminomutase Bcen_0482 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 107022181 Common - protein of unknown function DUF195 Bcen_0625 96 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 107022532 Common - phospholipid/glycerol acyltransferase Bcen_0977 149 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 107021647 Common - preprotein translocase subunit SecA Bcen_0087 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 107022859 Common - Catechol 1,2-dioxygenase Bcen_1307 51 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 107022105 Common - General substrate transporter Bcen_0548 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023225 Common - Potassium-translocating P-type ATPase, B subunit Bcen_1675 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 107022424 Common - transport system permease protein Bcen_0869 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 107022426 Common - two component transcriptional regulator, winged helix family Bcen_0871 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107022257 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Bcen_0701 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 107021992 Common - hypothetical protein Bcen_0434 4 None None None 107022217 Common - elongation factor P Bcen_0661 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 107023177 Common - NADH dehydrogenase subunit L Bcen_1626 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 107023619 Common - transcriptional regulator, LacI family Bcen_2072 29 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 107024245 Common - D-amino-acid dehydrogenase Bcen_2701 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 107023815 Common - YadA-like Bcen_2268 38 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 107024376 Common - 5,10-methylenetetrahydrofolate reductase Bcen_2833 149 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 107024380 Common - flagellar biosynthesis protein, FlhG Bcen_2837 69 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107022196 Common - fatty acid/phospholipid synthesis protein Bcen_0640 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 107023331 Pathogen - hypothetical protein Bcen_1782 1 None None None 107022729 Common - Cobalamin (vitamin B12) biosynthesis CobW Bcen_1176 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 107022568 Common - aspartate aminotransferase Bcen_1014 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 107021658 Common - Trans-hexaprenyltranstransferase Bcen_0098 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 107023241 Common - hypothetical protein Bcen_1691 11 None None None 107023027 Common - NADH:flavin oxidoreductase/NADH oxidase Bcen_1475 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 107022634 Common - hypothetical protein Bcen_1081 3 None None None 107022923 Common - short chain dehydrogenase Bcen_1371 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107024110 Common - Phenylacetic acid degradation protein PaaD Bcen_2565 61 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 107021783 Common - hypothetical protein Bcen_0223 3 None None None 107023468 Common - aldo/keto reductase Bcen_1919 181 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 107022274 Common - acriflavin resistance protein Bcen_0718 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 107021857 Common - beta-ketoacyl synthase Bcen_0299 222 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 107021693 Pathogen - hypothetical protein Bcen_0133 1 None None None 107021705 Common - CinA-like Bcen_0145 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 107022080 Common - (p)ppGpp synthetase I, SpoT/RelA Bcen_0522 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 107022823 Pathogen - hypothetical protein Bcen_1271 1 None None None 107022220 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Bcen_0664 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 107022013 Common - Lysine exporter protein (LYSE/YGGA) Bcen_0455 69 COG1279 COG1279, Lysine efflux permease General function prediction only 107024017 Common - protein of unknown function DUF484 Bcen_2472 38 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 107023101 Common - NmrA-like Bcen_1550 38 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107024341 Common - major facilitator superfamily MFS_1 Bcen_2797 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022951 Common - transcriptional regulator, GntR family Bcen_1399 219 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 107021741 Common - transcriptional regulator, TetR family Bcen_0181 39 COG1309 AcrR, Transcriptional regulator Transcription 107021629 Common - hypothetical protein Bcen_0068 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 107024359 Common - phosphoheptose isomerase Bcen_2815 104 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 107023997 Common fliH flagellar assembly protein H Bcen_2452 25 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 107023573 Common - peptidase M48, Ste24p Bcen_2026 131 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 107021824 Pathogen - hypothetical protein Bcen_0264 1 None None None 107023181 Common - NADH dehydrogenase subunit H Bcen_1630 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 107023275 Common - Na+/solute symporter Bcen_1725 61 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 107023678 Common - Peptidase C56, PfpI Bcen_2131 114 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 107021726 Common - ferric uptake regulator, Fur family Bcen_0166 193 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 107023803 Common - Redoxin Bcen_2256 130 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 107024264 Common - Penicillin-binding protein 1A Bcen_2720 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 107021806 Common - pyrroline-5-carboxylate reductase Bcen_0246 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 107023968 Common - hypothetical protein Bcen_2423 101 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 107022141 Common - electron transfer flavoprotein, alpha subunit Bcen_0584 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 107022215 Common - beta-hexosaminidase Bcen_0659 172 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 107022556 Pathogen - protein of unknown function DUF811 Bcen_1001 3 None None None 107022805 Common - oxidoreductase Bcen_1253 66 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022045 Common - 6-phosphogluconolactonase Bcen_0487 104 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 107024450 Common - hypothetical protein Bcen_2908 3 None None None 107021568 Common - cobalamin synthesis protein, P47K Bcen_0006 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 107022516 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Bcen_0961 74 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 107022933 Common - glycosyl transferase, family 9 Bcen_1381 88 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107023056 Common - heavy metal sensor signal transduction histidine kinase Bcen_1504 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107022011 Common - protein of unknown function DUF861, cupin_3 Bcen_0453 37 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 107021844 Common - Capsule polysaccharide biosynthesis Bcen_0285 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 162218045 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Bcen_2942 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 107023831 Common - Mammalian cell entry related Bcen_2284 64 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 107022943 Common - multi-sensor hybrid histidine kinase Bcen_1391 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 107024403 Common - Cof protein Bcen_2860 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 107022682 Common - transcriptional regulator, LacI family Bcen_1129 130 COG1609 PurR, Transcriptional regulators Transcription 107022850 Common - secretion protein HlyD Bcen_1298 86 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 107023389 Common - Phosphoglycerate mutase Bcen_1840 31 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 107021794 Common - peptidase S41 Bcen_0234 158 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 107022371 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Bcen_0815 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 107022261 Common - succinylarginine dihydrolase Bcen_0705 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 107021655 Common - type II secretion system protein Bcen_0095 137 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 107023956 Common flgB flagellar basal body rod protein FlgB Bcen_2411 76 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 107024098 Common dnaA chromosomal replication initiation protein Bcen_2553 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 107023048 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1496 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107023508 Common - protein of unknown function DUF72 Bcen_1959 42 COG1801 COG1801, Uncharacterized conserved protein Function unknown 107023938 Pathogen - hypothetical protein Bcen_2393 1 None None None 107021573 Common - hypothetical protein Bcen_0011 4 None None None 107022357 Pathogen - hypothetical protein Bcen_0801 1 None None None 107022751 Common - precorrin-4 C11-methyltransferase Bcen_1198 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 107023043 Common - hypothetical protein Bcen_1491 13 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 107023149 Common - transcriptional regulator, TetR family Bcen_1598 66 COG1309 AcrR, Transcriptional regulator Transcription 107024459 Common - acetolactate synthase 2 catalytic subunit Bcen_2917 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 107024468 Common - Ethanolamine ammonia lyase large subunit Bcen_2926 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 107021710 Common - hypothetical protein Bcen_0150 15 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 107024428 Common - hypothetical protein Bcen_2886 8 None None None 107022316 Common - transcriptional regulator, LysR family Bcen_0760 166 COG0583 LysR, Transcriptional regulator Transcription 107022096 Common - guanine deaminase Bcen_0539 143 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 107022154 Common - ribosome-associated GTPase Bcen_0597 163 COG1162 COG1162, Predicted GTPases General function prediction only 107023198 Common - 2-isopropylmalate synthase Bcen_1648 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 107023010 Common - transcriptional regulator, AraC family Bcen_1458 129 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107022839 Common - transport-associated Bcen_1287 6 None None None 107022176 Common - 4Fe-4S ferredoxin, iron-sulfur binding Bcen_0620 154 COG1146 COG1146, Ferredoxin Energy production and conversion 107021673 Common - ribonucleotide-diphosphate reductase subunit beta Bcen_0113 162 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 107021887 Common - Peroxidase Bcen_0329 211 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 107023710 Common - single-strand DNA-binding protein Bcen_2163 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 107023230 Common - short-chain dehydrogenase/reductase SDR Bcen_1680 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023942 Common - Chromate transporter Bcen_2397 32 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 107023608 Common - hypothetical protein Bcen_2061 9 None None None 107024026 Pathogen - hypothetical protein Bcen_2481 1 None None None 107021763 Common - hypothetical protein Bcen_0203 9 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 107023259 Common - cell divisionFtsK/SpoIIIE Bcen_1709 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 107023824 Common - aminotransferase, class IV Bcen_2277 188 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 107023426 Pathogen - hypothetical protein Bcen_1877 1 None None None 107022038 Common - riboflavin synthase subunit alpha Bcen_0480 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 107023877 Common - K+ channel, inward rectifier, conserved region 2 Bcen_2330 18 None None None 107022547 Pathogen - hypothetical protein Bcen_0992 1 None None None 107022338 Common - heat shock protein Hsp20 Bcen_0782 131 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 107023581 Common - O-antigen polymerase Bcen_2034 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 107023861 Common - short chain dehydrogenase Bcen_2314 115 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 107022551 Common rplT 50S ribosomal protein L20 Bcen_0996 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 107022580 Common - GTP-binding protein TypA Bcen_1027 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 107023112 Common - two component transcriptional regulator, winged helix family Bcen_1561 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107024134 Common - isochorismatase hydrolase Bcen_2589 82 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 107022188 Common - Pseudouridine synthase, RluD Bcen_0632 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 107024350 Common - Carotenoid oxygenase Bcen_2806 35 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 107023346 Common - transcriptional regulator, LysR family Bcen_1797 88 COG0583 LysR, Transcriptional regulator Transcription 107023784 Common - RNA methyltransferase TrmH, group 2 Bcen_2237 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 107023847 Common - hypothetical protein Bcen_2300 16 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 107024092 Common trmE tRNA modification GTPase TrmE Bcen_2547 228 COG0486 ThdF, Predicted GTPase General function prediction only 107023681 Common - hypothetical protein Bcen_2134 23 None None None 107023644 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Bcen_2097 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 107022430 Common - porin, Gram-negative type Bcen_0875 33 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 107023122 Common - Sel1-like repeat Bcen_1571 55 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 107023251 Common dnaE DNA polymerase III subunit alpha Bcen_1701 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 107023405 Common - permease YjgP/YjgQ Bcen_1856 82 COG0795 COG0795, Predicted permeases General function prediction only 107023730 Common - A/G-specific adenine glycosylase Bcen_2183 222 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 107021983 Common - hypothetical protein Bcen_0425 19 None None None 107022026 Common - protein of unknown function DUF190 Bcen_0468 31 COG1993 COG1993, Uncharacterized conserved protein Function unknown 107023658 Common - phospholipase D/Transphosphatidylase Bcen_2111 150 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 107023191 Common - Alcohol dehydrogenase, zinc-binding Bcen_1640 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 107022508 Pathogen - hypothetical protein Bcen_0953 1 None None None 107024207 Common - glutathione S-transferase-like Bcen_2663 118 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107022392 Common - Aldose 1-epimerase Bcen_0837 63 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 107023554 Common - periplasmic sensor signal transduction histidine kinase Bcen_2007 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 107024128 Common - GABA permease Bcen_2583 176 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 107022895 Pathogen - hypothetical protein Bcen_1343 1 COG5038 COG5038, Ca2+-dependent lipid-binding protein, contains C2 domain General function prediction only 107022904 Common - RNA polymerase factor sigma-54 Bcen_1352 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 107021602 Common - two component transcriptional regulator, winged helix family Bcen_0040 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 107021717 Common - transcriptional regulator, LysR family Bcen_0157 188 COG0583 LysR, Transcriptional regulator Transcription 107023082 Common - transcriptional regulator, DeoR family Bcen_1531 87 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 107022734 Common - Tetratricopeptide TPR_2 Bcen_1181 72 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 107023370 Common - Lysine decarboxylase Bcen_1821 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 107023705 Common - acetyl-CoA acetyltransferase Bcen_2158 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 107024425 Common - hypothetical protein Bcen_2883 16 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 107024257 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Bcen_2713 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 107021891 Common - diguanylate phosphodiesterase Bcen_0333 17 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 107022470 Common - DoxX Bcen_0915 16 COG2259 COG2259, Predicted membrane protein Function unknown 107023155 Common - hypothetical protein Bcen_1604 10 None None None 107022307 Common - binding-protein-dependent transport systems inner membrane component Bcen_0751 125 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 107022409 Common - UDP-N-acetylglucosamine 2-epimerase Bcen_0854 156 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 107022223 Common - GCN5-related N-acetyltransferase Bcen_0667 76 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 107023350 Common - protein of unknown function DUF482 Bcen_1801 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 107023438 Common - peptidylprolyl isomerase, FKBP-type Bcen_1889 131 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 107022990 Common - phage integrase Bcen_1438 200 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 107022211 Common era GTP-binding protein Era Bcen_0655 231 COG1159 Era, GTPase General function prediction only 107022324 Common - permease for cytosine/purines, uracil, thiamine, allantoin Bcen_0768 40 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 107022301 Common - transcriptional regulator, XRE family Bcen_0745 29 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 107023548 Common - isochorismatase hydrolase Bcen_2001 91 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 107024486 Common hemE uroporphyrinogen decarboxylase Bcen_2944 178 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 107024212 Common - peptidase S1 and S6, chymotrypsin/Hap Bcen_2668 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 107022984 Common - transcriptional regulator, GntR family Bcen_1432 223 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 107022131 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Bcen_0574 228 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107024511 Common - inner-membrane translocator Bcen_2969 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 107024072 Common - extracellular solute-binding protein, family 3 Bcen_2527 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107023364 Common - Methyltransferase type 11 Bcen_1815 199 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 107022236 Common - ABC transporter related Bcen_0680 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 107023779 Common - Cytochrome-c oxidase Bcen_2232 170 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 107021751 Common - glutamine amidotransferase, class-II Bcen_0191 73 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 107021968 Common - UDP-glucose 4-epimerase Bcen_0410 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 107023780 Common - cytochrome c oxidase, subunit II Bcen_2233 156 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 107023324 Common - ecotin precursor Bcen_1775 23 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 107022127 Pathogen - hypothetical protein Bcen_0570 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 107023750 Common - cytochrome bd ubiquinol oxidase, subunit I Bcen_2203 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 107024457 Common - Addiction module toxin, RelE/StbE Bcen_2915 13 COG3668 ParE, Plasmid stabilization system protein General function prediction only 107024163 Common - peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins Bcen_2619 9 None None None 107024392 Common - methyl-accepting chemotaxis sensory transducer Bcen_2849 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 107023535 Common - sorbitol dehydrogenase Bcen_1988 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107022101 Common - transcriptional regulator, GntR family Bcen_0544 122 COG1802 GntR, Transcriptional regulators Transcription 107024490 Common atpC F0F1 ATP synthase subunit epsilon Bcen_2948 181 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 107024291 Common rplE 50S ribosomal protein L5 Bcen_2747 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 107024320 Common - Phenylacetate-CoA oxygenase, PaaG subunit Bcen_2776 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 107022582 Common - dihydrolipoamide acetyltransferase Bcen_1029 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 107024041 Common - cell shape determining protein, MreB/Mrl family Bcen_2496 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 107022973 Common - cytochrome d ubiquinol oxidase, subunit II Bcen_1421 151 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 107024244 Common - major facilitator superfamily MFS_1 Bcen_2700 202 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022668 Common - ABC-2 type transporter, NodJ family Bcen_1115 110 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 107023072 Common - glucose-methanol-choline oxidoreductase Bcen_1520 80 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 107024518 Common - transcriptional regulator, AsnC family Bcen_2976 155 COG1522 Lrp, Transcriptional regulators Transcription 107022701 Common - pili assembly chaperone Bcen_1148 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 107022360 Common - ribonuclease H Bcen_0804 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 107022757 Common - transposase, mutator type Bcen_1204 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023415 Common - ABC branched chain amino acid family transporter, periplasmic ligand binding protein Bcen_1866 79 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107024387 Common - chemotaxis regulator CheZ Bcen_2844 42 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 107023216 Common - Threonyl/alanyl tRNA synthetase, SAD Bcen_1666 153 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 107022385 Common - phosphohistidine phosphatase, SixA Bcen_0829 75 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 107022921 Common - hypothetical protein Bcen_1369 6 None None None 107023541 Common - Alcohol dehydrogenase, zinc-binding Bcen_1994 201 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 107021957 Common - mannose-6-phosphate isomerase, type II Bcen_0399 120 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 107023940 Common - protein of unknown function DUF1275 Bcen_2395 16 COG3619 COG3619, Predicted membrane protein Function unknown 107022437 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_0882 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 107022242 Common - Extracellular ligand-binding receptor Bcen_0686 141 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 107023367 Common - argininosuccinate lyase Bcen_1818 231 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 107024438 Common - hypothetical protein Bcen_2896 4 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 107023310 Common - hypothetical protein Bcen_1761 6 None None None 107023840 Common - RfaE bifunctional protein, domain II Bcen_2293 124 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 107023171 Common - acyl-CoA dehydrogenase-like Bcen_1620 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 107022484 Common - protein of unknown function DUF1228 Bcen_0929 62 None None None 107023359 Common - alpha/beta hydrolase fold Bcen_1810 86 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107023775 Common - cytochrome c oxidase, subunit III Bcen_2228 152 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 107023902 Common - Bile acid:sodium symporter Bcen_2356 57 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 107022917 Common - natural resistance-associated macrophage protein Bcen_1365 96 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 107022575 Common rbfA ribosome-binding factor A Bcen_1021 159 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 107022364 Common - major facilitator superfamily MFS_1 Bcen_0808 71 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107023859 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein Bcen_2312 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 107024514 Common - ABC transporter related Bcen_2972 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 107024085 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Bcen_2540 25 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 107023471 Common - Citrate synthase Bcen_1922 98 COG0372 GltA, Citrate synthase Energy production and conversion 107021897 Common - major facilitator superfamily MFS_1 Bcen_0339 57 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022542 Common - protein of unknown function DUF1486 Bcen_0987 22 COG5485 COG5485, Predicted ester cyclase General function prediction only 107022789 Common - hypothetical protein Bcen_1236 10 None None None 107022376 Common pstC phosphate transporter permease subunit Bcen_0820 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 107022869 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Bcen_1317 180 COG0546 Gph, Predicted phosphatases General function prediction only 107022440 Common - citrate transporter Bcen_0885 41 COG2851 CitM, H+/citrate symporter Energy production and conversion 107022156 Common - oligoribonuclease Bcen_0599 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 107021871 Pathogen - hypothetical protein Bcen_0313 1 None None None 107021683 Common - 3-dehydroquinate dehydratase Bcen_0123 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 107022342 Common - malonate transporter MadL subunit Bcen_0786 11 None None None 107023130 Pathogen - hypothetical protein Bcen_1579 1 None None None 107021804 Common - Ferritin and Dps Bcen_0244 146 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 107023931 Common - binding-protein-dependent transport systems inner membrane component Bcen_2385 201 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 107024322 Common - Phenylacetate-CoA oxygenase, PaaI subunit Bcen_2778 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 107023343 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1794 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 107022743 Common - Chitinase Bcen_1190 34 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 107022994 Common - hypothetical protein Bcen_1442 3 None None None 107021852 Common - Integrase, catalytic region Bcen_0294 129 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 107022413 Common - Twin-arginine translocation pathway signal Bcen_0858 112 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 107024444 Common - Alkylhydroperoxidase AhpD core Bcen_2902 76 COG2128 COG2128, Uncharacterized conserved protein Function unknown 107024442 Common - IstB-like ATP-binding protein Bcen_2900 108 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 107022813 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_1261 149 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 107023614 Common glpK glycerol kinase Bcen_2067 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 107023588 Common recA recombinase A Bcen_2041 227 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 107024224 Common hisB imidazoleglycerol-phosphate dehydratase Bcen_2680 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 107023409 Common - Sulfate adenylyltransferase, large subunit Bcen_1860 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 107022537 Common - transcriptional regulator, LuxR family Bcen_0982 50 COG4566 TtrR, Response regulator Signal transduction mechanisms 107022601 Common - membrane protein Bcen_1048 4 COG4655 COG4655, Predicted membrane protein Function unknown 107024133 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Bcen_2588 43 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 107021630 Common mraW S-adenosyl-methyltransferase MraW Bcen_0069 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 107022434 Common - TonB-dependent siderophore receptor Bcen_0879 103 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 107023315 Pathogen - hypothetical protein Bcen_1766 1 COG2135 COG2135, Uncharacterized conserved protein Function unknown 107022276 Common - transcriptional regulator, IclR family Bcen_0720 111 COG1414 IclR, Transcriptional regulator Transcription 107022561 Pathogen - hypothetical protein Bcen_1007 1 None None None 107022296 Pathogen - hypothetical protein Bcen_0740 1 None None None 107023631 Common - ChaC-like protein Bcen_2084 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 107023924 Pathogen - hypothetical protein Bcen_2378 1 None None None 107022565 Pathogen - hypothetical protein Bcen_1011 1 None None None 107023372 Common - superoxide dismutase, copper/zinc binding Bcen_1823 55 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 107023761 Common - hypothetical protein Bcen_2214 57 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 107023053 Common - acriflavin resistance protein Bcen_1501 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 107023487 Common - integral membrane protein MviN Bcen_1938 186 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 107022182 Common - GCN5-related N-acetyltransferase Bcen_0626 83 COG0456 RimI, Acetyltransferases General function prediction only 107022405 Common - hypothetical protein Bcen_0850 3 None None None 107022639 Pathogen - hypothetical protein Bcen_1086 1 None None None 107022402 Common - hypothetical protein Bcen_0847 3 None None None 107021714 Common - spermidine synthase Bcen_0154 113 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 107022210 Common - Ribonuclease III Bcen_0654 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 107024303 Common rplC 50S ribosomal protein L3 Bcen_2759 222 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 107023501 Common - N-acetylmuramoyl-L-alanine amidase Bcen_1952 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 107024312 Common rplL 50S ribosomal protein L7/L12 Bcen_2768 212 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 107023987 Common - amino acid permease-associated region Bcen_2442 185 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 107023952 Common flgF flagellar basal body rod protein FlgF Bcen_2407 126 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 107023090 Common - Ribokinase Bcen_1539 182 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 107023609 Common - Gamma-glutamyltransferase Bcen_2062 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 107023989 Common - PepSY-associated TM helix Bcen_2444 4 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 107022845 Common - cytochrome c oxidase, subunit I Bcen_1293 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 107021708 Common - malic enzyme Bcen_0148 212 COG0281 SfcA, Malic enzyme Energy production and conversion 107023674 Common - Endoribonuclease L-PSP Bcen_2127 177 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 107021815 Common - peptidase U62, modulator of DNA gyrase Bcen_0255 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 107023202 Common - ketol-acid reductoisomerase Bcen_1652 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 107023617 Common - MocE Rieske (2Fe-2S) Bcen_2070 79 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 107022009 Pathogen - hypothetical protein Bcen_0451 1 None None None 107024008 Common - aldo/keto reductase Bcen_2463 194 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 107024378 Common - S-adenosyl-L-homocysteine hydrolase Bcen_2835 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 107022103 Common - hypothetical protein Bcen_0546 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 107021773 Common - Glutamate synthase (NADPH) Bcen_0213 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 107023543 Common - uracil-xanthine permease Bcen_1996 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 107023447 Common - Fmu (Sun) Bcen_1898 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 107022759 Common - ABC transporter related Bcen_1206 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 107022513 Common - UTP-glucose-1-phosphate uridylyltransferase Bcen_0958 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 107023912 Common - PP-loop Bcen_2366 168 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 107023651 Common - hypothetical protein Bcen_2104 10 None None None 107022002 Pathogen - hypothetical protein Bcen_0444 1 None None None 107024170 Common - hypothetical protein Bcen_2626 11 None None None 107024220 Common - imidazole glycerol phosphate synthase subunit HisF Bcen_2676 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 107022673 Common - LexA repressor Bcen_1120 171 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 107023336 Pathogen - hypothetical protein Bcen_1787 1 None None None 107021946 Common apaH diadenosine tetraphosphatase Bcen_0388 76 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 107022456 Pathogen - hypothetical protein Bcen_0901 1 None None None 107024051 Common - response regulator receiver protein Bcen_2506 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 107021625 Common - acyl-CoA synthetase Bcen_0064 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 162218052 Common metG methionyl-tRNA synthetase Bcen_1826 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107021986 Common - ABC transporter related Bcen_0428 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 107021594 Common - flagellar biosynthesis protein, FliO Bcen_0032 33 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 107024273 Common - delta-aminolevulinic acid dehydratase Bcen_2729 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 107024050 Common - ExsB Bcen_2505 173 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 107024272 Common - GTPase EngB Bcen_2728 172 COG0218 COG0218, Predicted GTPase General function prediction only 107024416 Common - hypothetical protein Bcen_2874 35 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 107023470 Common - L-carnitine dehydratase/bile acid-inducible protein F Bcen_1921 114 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 107021942 Common - pyrimidine regulatory protein PyrR Bcen_0384 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 107022498 Common - ABC transporter related Bcen_0943 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 107024413 Pathogen - GCN5-related N-acetyltransferase Bcen_2871 1 COG0456 RimI, Acetyltransferases General function prediction only 107023919 Common - iron permease FTR1 Bcen_2373 58 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 107021827 Common - hypothetical protein Bcen_0267 4 None None None 107021912 Common - transposase IS116/IS110/IS902 Bcen_0354 22 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023854 Common - DSBA oxidoreductase Bcen_2307 66 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 107021919 Common - protein of unknown function DUF81 Bcen_0361 40 COG0730 COG0730, Predicted permeases General function prediction only 107023802 Common - hypothetical protein Bcen_2255 4 None None None 107023161 Common - peptidase M14, carboxypeptidase A Bcen_1610 29 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 107024277 Common - DNA-directed RNA polymerase subunit alpha Bcen_2733 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 107024036 Common - exodeoxyribonuclease III (xth) Bcen_2491 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 107023065 Common - glycoside hydrolase, family 3-like Bcen_1513 73 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 107024188 Common - hypothetical protein Bcen_2644 3 None None None 107023525 Common - major facilitator superfamily MFS_1 Bcen_1978 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107021999 Common - Cobyrinic acid a,c-diamide synthase Bcen_0441 193 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107021861 Common - Adenylylsulfate kinase Bcen_0303 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 162218061 Common glyA serine hydroxymethyltransferase Bcen_0323 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 107021964 Common - NAD-dependent epimerase/dehydratase Bcen_0406 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 107023304 Pathogen - hypothetical protein Bcen_1755 1 None None None 107021924 Common - extracellular solute-binding protein, family 3 Bcen_0366 172 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107021785 Common - site-specific recombinase-like Bcen_0225 23 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 107021651 Common - protein of unknown function DUF329 Bcen_0091 60 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 107022043 Common - Drug resistance transporter Bcr/CflA subfamily Bcen_0485 227 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 107022775 Pathogen - hypothetical protein Bcen_1222 1 None None None 107023419 Common - alpha/beta hydrolase fold Bcen_1870 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 107021620 Common - putative transmembrane anti-sigma factor Bcen_0059 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 107022530 Common - membrane protein Bcen_0975 21 COG4323 COG4323, Predicted membrane protein Function unknown 107022117 Common - OmpA/MotB Bcen_0560 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 107023893 Common - YbaK/prolyl-tRNA synthetase associated region Bcen_2346 57 COG2606 EbsC, Uncharacterized conserved protein Function unknown 107024284 Common rplO 50S ribosomal protein L15 Bcen_2740 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 107024250 Common - protein of unknown function DUF1568 Bcen_2706 50 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 107023646 Common - Organic solvent tolerance protein Bcen_2099 125 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 107023041 Common - transcriptional regulator, LysR family Bcen_1489 98 COG0583 LysR, Transcriptional regulator Transcription 107024210 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit Bcen_2666 91 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 107021748 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Bcen_0188 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 107021640 Common - D-alanine--D-alanine ligase Bcen_0079 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 107023743 Common - maleylacetoacetate isomerase Bcen_2196 103 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 107023412 Common - Uncharacterised conserved protein UCP030820 Bcen_1863 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 107022331 Common - transcriptional regulator, LysR family Bcen_0775 181 COG0583 LysR, Transcriptional regulator Transcription 107021694 Common - transcriptional regulator, IclR family Bcen_0134 117 COG1414 IclR, Transcriptional regulator Transcription 107022768 Common - esterase/lipase-like protein Bcen_1215 55 COG0657 Aes, Esterase/lipase Lipid metabolism 107021616 Pathogen - hypothetical protein Bcen_0055 1 None None None 107023257 Common purT phosphoribosylglycinamide formyltransferase 2 Bcen_1707 189 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 107022717 Common - TonB-dependent siderophore receptor Bcen_1164 109 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 107022239 Common - membrane protein-like Bcen_0683 5 COG3556 COG3556, Predicted membrane protein Function unknown 107024151 Common - protein of unknown function DUF1415 Bcen_2607 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 107023227 Pathogen - potassium-transporting ATPase, KdpF subunit-related protein Bcen_1677 1 None None None 107022880 Common - Endonuclease/exonuclease/phosphatase Bcen_1328 78 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 107021733 Common holA DNA polymerase III subunit delta Bcen_0173 73 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 107022422 Common - ABC transporter related Bcen_0867 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 107024507 Common - inner-membrane translocator Bcen_2965 120 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 107022857 Common - 2-chlorobenzoate 1,2-dioxygenase Bcen_1305 18 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 107022191 Common - peptidase S49 Bcen_0635 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 107023767 Common - Lipoprotein YaeC Bcen_2220 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 107022925 Common - glycosyl transferase, group 1 Bcen_1373 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 107023001 Common - transcriptional regulator, LysR family Bcen_1449 125 COG0583 LysR, Transcriptional regulator Transcription 107024371 Common - major facilitator superfamily (MFS_1) transporter Bcen_2828 41 None None None 107024492 Common - F0F1 ATP synthase subunit gamma Bcen_2950 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 107024432 Common - hypothetical protein Bcen_2890 3 None None None 107024236 Common - protein of unknown function DUF140 Bcen_2692 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 107022198 Common - malonyl CoA-acyl carrier protein transacylase Bcen_0642 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 107023121 Common - hypothetical protein Bcen_1570 11 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 107022618 Common - ABC transporter, substrate-binding protein, aliphatic sulphonates Bcen_1065 73 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 107022449 Common - dual specificity protein phosphatase Bcen_0894 18 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 107024361 Common - Protein of unknown function UPF0011 Bcen_2817 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 107023455 Common - amino acid permease-associated region Bcen_1906 142 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 107022782 Common - amidohydrolase Bcen_1229 78 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 107022967 Common - hypothetical protein Bcen_1415 2 None None None 107024294 Common rpsQ 30S ribosomal protein S17 Bcen_2750 227 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 107023233 Common - phosphoribosylamine--glycine ligase Bcen_1683 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 107023019 Common - secretion protein HlyD Bcen_1467 111 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 107024158 Common - transcriptional regulator, LysR family Bcen_2614 170 COG0583 LysR, Transcriptional regulator Transcription 107022172 Common - branched-chain amino acid transport Bcen_0616 8 COG4392 COG4392, Predicted membrane protein Function unknown 107023575 Common - Rhs element Vgr protein Bcen_2028 48 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 107023688 Common - hypothetical protein Bcen_2141 2 None None None 107022441 Common - protein of unknown function DUF1446 Bcen_0886 35 None None None 107022795 Common - binding-protein-dependent transport systems inner membrane component Bcen_1242 165 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 107023720 Common - Phosphatase kdsC Bcen_2173 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 107022064 Common - cell division topological specificity factor MinE Bcen_0506 87 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 107021753 Common - hypothetical protein Bcen_0193 13 None None None 107024087 Pathogen - hypothetical protein Bcen_2542 1 None None None 107023512 Common - hypothetical protein Bcen_1963 11 None None None 107021790 Common - cytochrome B561 Bcen_0230 85 COG3038 CybB, Cytochrome B561 Energy production and conversion 107023490 Pathogen - ornithine carbamoyltransferase Bcen_1941 1 None None None 107022486 Common - thioesterase superfamily Bcen_0931 61 COG0824 FcbC, Predicted thioesterase General function prediction only 107023972 Common dppF dipeptide transporter ATP-binding subunit Bcen_2427 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 107023058 Common - transcriptional regulator, AraC family Bcen_1506 108 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 107022068 Common - Lipopolysaccharide heptosyltransferase I Bcen_0510 69 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 107022468 Common - hypothetical protein Bcen_0913 16 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 107022833 Common - RND efflux system, outer membrane lipoprotein, NodT Bcen_1281 117 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 107022909 Pathogen - hypothetical protein Bcen_1357 1 None None None 107021831 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Bcen_0271 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 107022004 Pathogen - hypothetical protein Bcen_0446 1 None None None 107023729 Common - peptidase S16, lon-like Bcen_2182 68 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 107022395 Common - RelA/SpoT Bcen_0840 10 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 107023999 Common - Flagellar export FliJ Bcen_2454 34 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 107022771 Common - glutathione-dependent formaldehyde-activating, GFA Bcen_1218 59 COG3791 COG3791, Uncharacterized conserved protein Function unknown 107023979 Common - FAD dependent oxidoreductase Bcen_2434 101 COG0579 COG0579, Predicted dehydrogenase General function prediction only 107022164 Common - transcriptional regulator, ArsR family Bcen_0608 35 COG0640 ArsR, Predicted transcriptional regulators Transcription 107024368 Common - cation diffusion facilitator family transporter Bcen_2824 212 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 107023520 Common - aldehyde dehydrogenase Bcen_1971 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 107021974 Common - hypothetical protein Bcen_0416 12 None None None 107023748 Common - RNA polymerase factor sigma-32 Bcen_2201 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 107022074 Common - coproporphyrinogen III oxidase Bcen_0516 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 107023966 Common - 5-formyltetrahydrofolate cyclo-ligase Bcen_2421 68 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 107024193 Common - extracellular solute-binding protein, family 3 Bcen_2649 192 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 107022345 Common - malonate decarboxylase subunit delta Bcen_0789 22 None None None 107024219 Common - Phosphoribosyl-AMP cyclohydrolase Bcen_2675 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 107023126 Common - hypothetical protein Bcen_1575 2 None None None 107022623 Common - GntR-like Bcen_1070 80 COG2186 FadR, Transcriptional regulators Transcription 107023212 Common - conserved hypothetical protein 730 Bcen_1662 129 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 107023875 Common - transferase hexapeptide repeat Bcen_2328 86 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 107021906 Common - molybdopterin dehydrogenase, FAD-binding Bcen_0348 121 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 107022373 Common - dihydropteroate synthase Bcen_0817 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 107023821 Common - hypothetical protein Bcen_2274 2 None None None 107024394 Common - CheA signal transduction histidine kinases Bcen_2851 150 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 107022314 Common - DoxX Bcen_0758 44 COG2259 COG2259, Predicted membrane protein Function unknown 107023168 Common - MaoC-like dehydratase Bcen_1617 76 COG2030 MaoC, Acyl dehydratase Lipid metabolism 107022024 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Bcen_0466 27 COG4934 COG4934, Predicted protease Posttranslational modification, protein turnover, chaperones 107023669 Common - histidine triad (HIT) protein Bcen_2122 45 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 107024148 Common - nitroreductase Bcen_2604 56 COG0778 NfnB, Nitroreductase Energy production and conversion 107022178 Common - protein of unknown function DUF162 Bcen_0622 80 COG1556 COG1556, Uncharacterized conserved protein Function unknown 162218046 Common - flagellin Bcen_2866 122 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 107023260 Common - 3-carboxymuconate cyclase-like Bcen_1710 69 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 107024064 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Bcen_2519 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 107022355 Pathogen - hypothetical protein Bcen_0799 1 None None None 107022529 Common - ribonuclease BN, putative Bcen_0974 125 COG1295 Rbn, Predicted membrane protein Function unknown 107024126 Common - translation-associated GTPase Bcen_2581 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 107021917 Common - DNA polymerase, beta-like region Bcen_0359 11 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 107024262 Pathogen - Fimbrial assembly Bcen_2718 1 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 107023232 Common - hypothetical protein Bcen_1682 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 107022506 Common - transcriptional regulator, LysR family Bcen_0951 131 COG0583 LysR, Transcriptional regulator Transcription 107024282 Common infA translation initiation factor IF-1 Bcen_2738 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 107024524 Common - nuclear protein SET Bcen_2982 24 COG2940 COG2940, Proteins containing SET domain General function prediction only 107023891 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Bcen_2344 217 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 107022333 Common - hypothetical protein Bcen_0777 13 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 107023629 Common - PhoH-like protein Bcen_2082 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 107023029 Common - Amidohydrolase 3 Bcen_1477 93 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 107022835 Common - secretion protein HlyD Bcen_1283 105 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 107023570 Common - hypothetical protein Bcen_2023 6 None None None 107023110 Common - transcriptional regulator, AraC family Bcen_1559 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023944 Common - uracil-xanthine permease Bcen_2399 128 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 107022094 Common - hypothetical protein Bcen_0537 7 None None None 107023530 Common - binding-protein-dependent transport systems inner membrane component Bcen_1983 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 107021760 Common - tyrosyl-tRNA synthetase Bcen_0200 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 107024343 Common - 6-phosphogluconate dehydrogenase, NAD-binding Bcen_2799 159 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 107022643 Common - hypothetical protein Bcen_1090 8 None None None 107022549 Common - translation initiation factor IF-3 Bcen_0994 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 107023298 Common - ABC transporter related Bcen_1749 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 107023699 Common - 3-oxoacyl-(acyl carrier protein) synthase I Bcen_2152 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107024010 Common - Phytanoyl-CoA dioxygenase Bcen_2465 36 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 107023348 Common - nitrogen regulatory protein P-II Bcen_1799 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 107022764 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Bcen_1211 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 107024399 Common - transcriptional activator FlhD Bcen_2856 27 None None None 107022359 Common - DNA polymerase III subunit epsilon Bcen_0803 189 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 107023267 Common - hypothetical protein Bcen_1717 23 None None None 107024161 Common - Mg2+ transporter protein, CorA-like Bcen_2617 59 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 107023147 Common - putative oxidoreductase Bcen_1596 187 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 107023671 Common - threonine dehydratase Bcen_2124 221 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 107023863 Common - dienelactone hydrolase and related enzymes-like Bcen_2316 24 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 107021994 Common - protein of unknown function UPF0153 Bcen_0436 36 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 107021564 Common - sodium/hydrogen exchanger Bcen_0002 18 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 107023382 Common - Cobyrinic acid a,c-diamide synthase Bcen_1833 108 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107022684 Common - methyl-accepting chemotaxis sensory transducer Bcen_1131 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 107021817 Common - hypothetical protein Bcen_0257 57 COG3164 COG3164, Predicted membrane protein Function unknown 107022890 Common - phosphatidylserine decarboxylase-related Bcen_1338 58 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 107023817 Common - ABC transporter related Bcen_2270 249 COG4525 TauB, ABC-type taurine transport system, ATPase component Inorganic ion transport and metabolism 107024357 Common - cytochrome c, class I Bcen_2813 28 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 107023833 Common - protein of unknown function DUF140 Bcen_2286 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 107022715 Common - hypothetical protein Bcen_1162 30 None None None 107022286 Common - extracellular solute-binding protein, family 1 Bcen_0730 111 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 107023182 Common - NADH dehydrogenase subunit G Bcen_1631 198 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 107022698 Pathogen - hypothetical protein Bcen_1145 1 None None None 107022935 Common - Carbamoyltransferase Bcen_1383 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 107022803 Common - transcriptional regulator, XRE family Bcen_1251 8 None None None 107022599 Common - Tetratricopeptide TPR_2 Bcen_1046 9 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 107024168 Pathogen - hypothetical protein Bcen_2624 1 COG4678 COG4678, Muramidase (phage lambda lysozyme) Carbohydrate transport and metabolism 107023247 Common - glycosyl transferase, family 2 Bcen_1697 21 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 107021622 Common - Catalase-like Bcen_0061 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 107021822 Common hemH ferrochelatase Bcen_0262 167 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 107024474 Common - transcriptional regulator, MerR family Bcen_2932 137 COG0789 SoxR, Predicted transcriptional regulators Transcription 107021889 Common - transcriptional regulator, IclR family Bcen_0331 87 COG1414 IclR, Transcriptional regulator Transcription 107024074 Common - Phosphonoacetate hydrolase Bcen_2529 13 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 107021765 Common ruvB Holliday junction DNA helicase B Bcen_0205 233 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 107023491 Common - ornithine carbamoyltransferase Bcen_1942 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 107023901 Pathogen - hypothetical protein Bcen_2355 1 None None None 107023157 Common - hypothetical protein Bcen_1606 9 None None None 107022797 Common - ABC transporter substrate binding protein Bcen_1244 23 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 107023561 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Bcen_2014 149 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 107023990 Common - putative flagellar protein FhlB Bcen_2445 74 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 107024316 Common nusG transcription antitermination protein NusG Bcen_2772 215 COG0250 NusG, Transcription antiterminator Transcription 107022590 Common - Flp/Fap pilin component Bcen_1037 29 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 107024038 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Bcen_2493 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 107024348 Common - protein of unknown function DUF214 Bcen_2804 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 107023340 Common - Pirin-like Bcen_1791 140 COG1741 COG1741, Pirin-related protein General function prediction only 107024103 Common - DNA (cytosine-5-)-methyltransferase Bcen_2558 7 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 107022520 Common - protein of unknown function DUF1656 Bcen_0965 10 None None None 107023403 Common - DNA polymerase III subunit chi Bcen_1854 35 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 107022696 Common - multidrug efflux protein Bcen_1143 180 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 107023322 Common - short-chain dehydrogenase/reductase SDR Bcen_1773 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 107023597 Common - transcriptional regulator, LysR family Bcen_2050 145 COG0583 LysR, Transcriptional regulator Transcription 107022238 Pathogen - hypothetical protein Bcen_0682 1 COG3402 COG3402, Uncharacterized conserved protein Function unknown 107022724 Common - Cobyrinic acid a,c-diamide synthase Bcen_1171 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 107023173 Common - NUDIX hydrolase Bcen_1622 164 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 107021842 Common - putative DedA family transmembrane protein Bcen_0282 154 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 107021868 Common - transcriptional modulator of MazE/toxin, MazF Bcen_0310 22 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 107021792 Common - YceI Bcen_0232 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 107022655 Pathogen - hypothetical protein Bcen_1102 1 None None None 107021835 Common - HAD-superfamily subfamily IB, PSPase-like Bcen_0275 71 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 107023846 Common - transcriptional regulator, IclR family Bcen_2299 85 COG1414 IclR, Transcriptional regulator Transcription 107022876 Pathogen - hypothetical protein Bcen_1324 1 None None None 107023747 Common - hypothetical protein Bcen_2200 8 None None None 107023291 Common - diguanylate cyclase/phosphodiesterase Bcen_1742 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 107023240 Common - protein of unknown function DUF469 Bcen_1690 26 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 107022707 Common - Taurine catabolism dioxygenase TauD/TfdA Bcen_1154 23 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 107024242 Common - ABC transporter-like Bcen_2698 246 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 162218062 Common rplM 50S ribosomal protein L13 Bcen_0196 225 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 107023398 Common - prolipoprotein diacylglyceryl transferase Bcen_1849 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 107021975 Common - 3-deoxy-D-manno-octulosonic-acid transferase Bcen_0417 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 107023273 Common - transaldolase B Bcen_1723 177 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 107023773 Common - hypothetical protein Bcen_2226 27 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 107024108 Common - beta-ketoadipyl CoA thiolase Bcen_2563 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 107024385 Common - hypothetical protein Bcen_2842 6 None None None 107022240 Common - Mandelate racemase/muconate lactonizing enzyme-like Bcen_0684 62 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 107022607 Common - AMP-dependent synthetase and ligase Bcen_1054 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 107023777 Common - cytochrome C oxidase assembly protein Bcen_2230 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 107021955 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Bcen_0397 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 107022283 Common - transcriptional regulator, AsnC family Bcen_0727 150 COG1522 Lrp, Transcriptional regulators Transcription 107022439 Common - transcriptional regulator, LysR family Bcen_0884 193 COG0583 LysR, Transcriptional regulator Transcription 107021950 Common - dTDP-4-dehydrorhamnose reductase Bcen_0392 163 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 107021691 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Bcen_0131 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 107023239 Common - ribonuclease, Rne/Rng family Bcen_1689 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 107022589 Common - hypothetical protein Bcen_1036 4 COG5412 COG5412, Phage-related protein Function unknown 107021604 Common - Site-specific DNA-methyltransferase (adenine-specific) Bcen_0042 91 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 107023683 Common - CHRD domain protein Bcen_2136 19 None None None 107022906 Pathogen - hypothetical protein Bcen_1354 1 None None None 107022955 Common - Dyp-type peroxidase Bcen_1403 54 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 107022748 Common - Precorrin-6y C5,15-methyltransferase, subunit CbiE Bcen_1195 94 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 107022982 Common - hypothetical protein Bcen_1430 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 107022120 Common - phosphoserine aminotransferase Bcen_0563 119 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 107024024 Common - response regulator receiver protein Bcen_2479 210 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 107022263 Pathogen - hypothetical protein Bcen_0707 1 None None None 107023926 Common - Glutamate--ammonia ligase Bcen_2380 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 107023642 Common - protein of unknown function DUF6, transmembrane Bcen_2095 27 None None None 107021893 Common - hypothetical protein Bcen_0335 14 None None None 107022732 Common - Mg-chelatase subunit ChlD-like Bcen_1179 16 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 107023914 Common - D-fructose-6-phosphate amidotransferase Bcen_2368 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 107024205 Common - phage integrase Bcen_2661 186 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 107023424 Common - copper resistance protein CopC Bcen_1875 22 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 107023084 Common - Na+/solute symporter Bcen_1533 111 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 107024094 Common - putative inner membrane protein translocase component YidC Bcen_2549 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 107024048 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Bcen_2503 84 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 107021872 Common - transcriptional regulator, XRE family Bcen_0314 16 None None None 107023707 Common - Cobyrinic acid a,c-diamide synthase Bcen_2160 205 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 107022135 Common - histone deacetylase superfamily Bcen_0578 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 107024259 Common aroK shikimate kinase Bcen_2715 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 107023393 Common - transport system permease protein Bcen_1844 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 107021674 Pathogen - hypothetical protein Bcen_0114 1 None None None 107022996 Pathogen - hypothetical protein Bcen_1444 2 None None None 107024015 Common - plasmid maintenance system killer Bcen_2470 34 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 107022893 Common - Peptidase C56, PfpI Bcen_1341 163 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 107023552 Common - hypothetical protein Bcen_2005 11 None None None 107022326 Common - transcriptional regulator, LysR family Bcen_0770 145 COG0583 LysR, Transcriptional regulator Transcription 107023431 Common - hypothetical protein Bcen_1882 13 COG5634 COG5634, Uncharacterized conserved protein Function unknown 107022471 Common - hypothetical protein Bcen_0916 4 None None None 107022989 Common - TfoX-like Bcen_1437 17 COG3070 TfoX, Regulator of competence-specific genes Transcription 107024079 Common - L-lactate transport Bcen_2534 104 COG1620 LldP, L-lactate permease Energy production and conversion 107022708 Common - ABC transporter related Bcen_1155 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 107023763 Common - ABC transporter related Bcen_2216 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 107023568 Common - hypothetical protein Bcen_2021 28 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 107023099 Common - transcriptional regulator, AraC family Bcen_1548 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 107023909 Common - protein of unknown function DUF185 Bcen_2363 87 COG1565 COG1565, Uncharacterized conserved protein Function unknown 107021800 Common - ATP-dependent DNA helicase RecG Bcen_0240 211 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 107022400 Common - phage integrase Bcen_0845 65 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 107022945 Pathogen - hypothetical protein Bcen_1393 1 COG4803 COG4803, Predicted membrane protein Function unknown 107024405 Common - DNA-3-methyladenine glycosylase I Bcen_2862 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 107022407 Common - glycosyl transferase, family 2 Bcen_0852 170 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane