Nitrobacter hamburgensis X14, complete genome NC_007964 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 92116553 Nonpathogen - hypothetical protein Nham_0970 4 None None None 92116852 Common - phosphoheptose isomerase Nham_1296 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 92117933 Nonpathogen - hypothetical protein Nham_2411 1 None None None 92119185 Common - transport system permease protein Nham_3730 175 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 92119357 Nonpathogen - hypothetical protein Nham_3946 1 None None None 92117082 Common rplJ 50S ribosomal protein L10 Nham_1529 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 92115907 Common - biotin synthase Nham_0277 174 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 92116638 Common - glucose-1-phosphate thymidylyltransferase Nham_1059 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 92116165 Common sucC succinyl-CoA synthetase subunit beta Nham_0544 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 92117814 Common - DNA repair protein RadA Nham_2291 209 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 92118833 Common - MCP methyltransferase, CheR-type Nham_3372 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 92115733 Common - Excinuclease ABC, C subunit-like Nham_0101 40 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 92118476 Common - transcriptional regulator, AraC family Nham_2987 41 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 92116295 Common metX homoserine O-acetyltransferase Nham_0676 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 92119162 Common rpmH 50S ribosomal protein L34 Nham_3705 25 None None None 92119145 Common - extracellular solute-binding protein, family 1 Nham_3686 89 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 92118515 Common - transferase hexapeptide repeat Nham_3038 214 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 92116124 Common - hypothetical protein Nham_0503 15 None None None 92118294 Nonpathogen - hypothetical protein Nham_2789 7 None None None 92118908 Common - peptidylprolyl isomerase, FKBP-type Nham_3448 126 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 92119234 Common - histidine kinase Nham_3783 169 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 92116244 Common rpmF 50S ribosomal protein L32 Nham_0625 98 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 92118053 Common - putative signal-transduction protein with CBS domains Nham_2540 16 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 92118365 Common - RNA polymerase sigma factor RpoD Nham_2866 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 92117554 Common - phage major capsid protein, HK97 Nham_2025 59 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 92118843 Nonpathogen - hypothetical protein Nham_3382 2 None None None 92116263 Common - GTP-binding protein TypA Nham_0644 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 92117782 Nonpathogen - hypothetical protein Nham_2259 2 None None None 92116550 Nonpathogen - hypothetical protein Nham_0967 1 COG4371 COG4371, Predicted membrane protein Function unknown 92116420 Nonpathogen - hypothetical protein Nham_0813 1 None None None 92116787 Common - NAD(P) transhydrogenase subunit alpha part Nham_1228 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 92119190 Common - Serine-type D-Ala-D-Ala carboxypeptidase Nham_3735 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 162211271 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Nham_1633 162 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 92116021 Common - translation initiation factor IF-1 Nham_0399 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 92116948 Common fliQ flagellar biosynthesis protein FliQ Nham_1395 18 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 92116336 Nonpathogen - hypothetical protein Nham_0720 1 None None None 92117407 Nonpathogen - hypothetical protein Nham_1862 1 None None None 92116481 Common - hypothetical protein Nham_0886 18 None None None 92116403 Common - hypothetical protein Nham_0794 6 None None None 92116597 Common - tyrosinase Nham_1018 8 None None None 92118027 Common - hypothetical protein Nham_2512 5 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 92116313 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Nham_0695 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 92117627 Common - putative glutathione S-transferase YghU Nham_2099 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92116270 Common - cytochrome c oxidase assembly protein CtaG/Cox11 Nham_0651 76 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 92118465 Common - Outer membrane autotransporter barrel Nham_2974 54 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 92118015 Nonpathogen - hypothetical protein Nham_2494 1 None None None 92115840 Common - putative glycosyl transferase Nham_0209 39 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92118335 Common - filamentation induced by cAMP protein Fic Nham_2833 46 COG3177 COG3177, Uncharacterized conserved protein Function unknown 92115805 Common - RNA polymerase factor sigma-54 Nham_0173 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 92117505 Common - hypothetical protein Nham_1974 13 None None None 92117915 Common - hypothetical protein Nham_2393 7 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 92116284 Common - response regulator receiver domain protein (CheY-like) Nham_0665 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92117215 Nonpathogen - hypothetical protein Nham_1667 1 None None None 92118710 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Nham_3244 93 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 92118782 Common - hypothetical protein Nham_3319 5 None None None 92116849 Common - UDP-glucose 4-epimerase Nham_1293 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 92117016 Common - Glycogen debranching enzyme GlgX Nham_1463 166 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 92116101 Common - phosphoribosyltransferase Nham_0480 164 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 92119169 Common - peptidase S1 and S6, chymotrypsin/Hap Nham_3712 210 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92119235 Nonpathogen - response regulator receiver domain protein (CheY-like) Nham_3784 2 None None None 92116467 Common - tISRso5; ISRSO5-transposase protein Nham_0871 47 None None None 92116909 Nonpathogen - hypothetical protein Nham_1354 6 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 92115849 Common - 2'-deoxycytidine 5'-triphosphate deaminase Nham_0218 31 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 92115657 Common - CBS:transporter-associated Nham_0024 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 92119048 Nonpathogen - hypothetical protein Nham_3589 3 None None None 92119110 Nonpathogen - hypothetical protein Nham_3651 1 None None None 92116950 Common flhB flagellar biosynthesis protein FlhB Nham_1397 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 92118137 Nonpathogen - hypothetical protein Nham_2624 4 None None None 92115899 Common - F0F1 ATP synthase subunit C Nham_0268 7 None None None 92118805 Common - protein of unknown function DUF1452 Nham_3342 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 92117738 Common - NADH-quinone oxidoreductase, F subunit Nham_2215 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 92116955 Common - protein of unknown function DUF1214 Nham_1402 32 COG5402 COG5402, Uncharacterized conserved protein Function unknown 92116060 Common - HPrNtr Nham_0439 128 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 92117440 Common - membrane protein Nham_1901 58 COG3174 COG3174, Predicted membrane protein Function unknown 92116830 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Nham_1274 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 92117097 Common rpsJ 30S ribosomal protein S10 Nham_1544 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 92119255 Nonpathogen - hypothetical protein Nham_3815 1 None None None 92115777 Common - glutathione synthetase Nham_0145 133 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 92117598 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Nham_2070 167 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 92116567 Common - UbiA prenyltransferase Nham_0986 10 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 92118169 Common - RNA polymerase sigma factor Nham_2659 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92119007 Common - protein of unknown function DUF1192 Nham_3547 8 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 92117427 Common - periplasmic sensor signal transduction histidine kinase Nham_1886 181 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92118044 Common - glycosyltransferase 36 Nham_2531 48 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 92118922 Common - Cytochrome-c oxidase Nham_3462 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 92117089 Common - hypothetical protein Nham_1536 21 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 92115876 Common - protein of unknown function DUF81 Nham_0245 38 COG0730 COG0730, Predicted permeases General function prediction only 92117392 Nonpathogen - hypothetical protein Nham_1847 3 None None None 92118243 Nonpathogen - hypothetical protein Nham_2733 3 None None None 92118520 Common - UDP-N-acetylglucosamine 2-epimerase Nham_3043 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 92118261 Nonpathogen - hypothetical protein Nham_2751 1 None None None 92116631 Common - Type I secretion membrane fusion protein, HlyD Nham_1052 117 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92117186 Common - phosphoribosylformylglycinamidine synthase II Nham_1636 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 92118437 Common - hypothetical protein Nham_2940 21 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 92118638 Common - CMP/dCMP deaminase, zinc-binding Nham_3172 207 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 92116344 Nonpathogen - TonB-like Nham_0730 6 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 92116411 Nonpathogen - hypothetical protein Nham_0802 4 None None None 92116425 Nonpathogen - hypothetical protein Nham_0818 9 None None None 92119211 Nonpathogen - hypothetical protein Nham_3756 1 None None None 92116136 Common rpmA 50S ribosomal protein L27 Nham_0515 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 92119095 Common - ApbE-like lipoprotein Nham_3636 134 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 92118681 Common - Farnesyltranstransferase Nham_3215 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 92119129 Nonpathogen - hypothetical protein Nham_3670 12 COG1416 COG1416, Uncharacterized conserved protein Function unknown 92118103 Common - xanthine-guanine phosphoribosyltransferase Nham_2590 64 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 92116102 Common - methyltransferase Nham_0481 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92116534 Common - protein of unknown function DUF442 Nham_0947 97 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 92118241 Common - protein of unknown function DUF1321 Nham_2731 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 92116859 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Nham_1303 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 92115745 Common - maf protein Nham_0113 182 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 92115878 Common - ISGsu3, transposase Nham_0247 31 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118220 Common - electron transport protein SCO1/SenC Nham_2710 66 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 92119432 Common - response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase Nham_4035 116 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 92119336 Common - FAD dependent oxidoreductase Nham_3916 97 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 92116223 Nonpathogen - hypothetical protein Nham_0603 1 None None None 92118157 Common - Drug resistance transporter Bcr/CflA subfamily Nham_2645 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92119324 Common - Recombinase Nham_3901 34 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92118033 Nonpathogen - hypothetical protein Nham_2520 1 None None None 92116910 Common - hypothetical protein Nham_1355 35 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 92117127 Common - Pseudouridine synthase, RluD Nham_1575 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 92117781 Common - Uracil-DNA glycosylase superfamily Nham_2258 96 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 92117762 Common - hypothetical protein Nham_2239 13 None None None 92118123 Nonpathogen - hypothetical protein Nham_2610 3 None None None 92118904 Common - major facilitator superfamily MFS_1 Nham_3444 100 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 92116107 Common - protein of unknown function DUF949 Nham_0486 53 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 92115799 Common - heat shock protein Hsp20 Nham_0167 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 92119371 Nonpathogen - peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins Nham_3964 2 None None None 92117276 Common - MoeA-like, domain I and II Nham_1730 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 92116602 Common - putative signal peptide protein Nham_1023 22 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 92117266 Common - phage major capsid protein, HK97 Nham_1719 54 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 92117256 Common gltX glutamyl-tRNA synthetase Nham_1709 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 92118219 Common - hypothetical protein Nham_2709 10 None None None 92116491 Nonpathogen - hypothetical protein Nham_0898 5 None None None 92115792 Common - transcriptional regulator, AraC family Nham_0160 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 92117460 Common - protein of unknown function DUF140 Nham_1921 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 92119401 Nonpathogen - hypothetical protein Nham_3999 4 None None None 92117841 Common - hypothetical protein Nham_2318 20 None None None 92118251 Common - ABC-2 Nham_2741 139 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 92117445 Common fixJ response regulator FixJ Nham_1906 220 COG4566 TtrR, Response regulator Signal transduction mechanisms 92118049 Common - Alcohol dehydrogenase, zinc-binding Nham_2536 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 92118643 Common - tetraacyldisaccharide 4'-kinase Nham_3177 129 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 92115919 Common - Maf-like protein Nham_0292 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 92119120 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Nham_3661 138 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 92116779 Common - protein of unknown function DUF1244 Nham_1220 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 92117238 Common - ISGsu2, transposase Nham_1690 38 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118915 Common - hypothetical protein Nham_3455 11 None None None 92115782 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Nham_0150 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 92118349 Nonpathogen - hypothetical protein Nham_2850 2 None None None 92117924 Common - hypothetical protein Nham_2402 6 None None None 92116975 Common - gene transfer agent (GTA) like protein Nham_1422 19 COG5281 COG5281, Phage-related minor tail protein Function unknown 92116416 Common - putative transposase Nham_0809 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118408 Common - Trans-aconitate 2-methyltransferase Nham_2909 82 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 92118099 Common - peptidase M29, aminopeptidase II Nham_2586 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 92117044 Common - conserved hypothetical protein 730 Nham_1491 108 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 92118443 Nonpathogen - hypothetical protein Nham_2946 1 None None None 92115979 Common - Extracellular ligand-binding receptor Nham_0352 97 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 92116863 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Nham_1307 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 92117603 Common - glycosyl transferase, family 2 Nham_2075 166 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92115703 Common - Twin-arginine translocation pathway signal Nham_0071 19 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 92117571 Common - hypothetical protein Nham_2042 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 92117869 Common - Alcohol dehydrogenase, zinc-binding Nham_2346 198 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 92116115 Nonpathogen - hypothetical protein Nham_0494 11 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 92119109 Common - tRNA-dihydrouridine synthase A Nham_3650 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 92117250 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase Nham_1703 189 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 92118326 Nonpathogen - hypothetical protein Nham_2824 2 None None None 92116443 Common - hypothetical protein Nham_0838 7 None None None 92118684 Common - Electron-transferring-flavoprotein dehydrogenase Nham_3218 109 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 92116003 Common - binding-protein-dependent transport systems inner membrane component Nham_0381 211 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 92116478 Nonpathogen - hypothetical protein Nham_0883 2 None None None 92117964 Common - response regulator receiver domain protein (CheY-like) Nham_2443 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 92118001 Common - phage Terminase Nham_2480 46 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 92117106 Common - 50S ribosomal protein L29 Nham_1553 171 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 92115699 Common - signal peptide peptidase SppA, 36K type Nham_0067 191 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 92118849 Common - Hly-III related proteins Nham_3388 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 92117305 Common - Beta-N-acetylhexosaminidase Nham_1760 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 92116139 Common - gamma-glutamyl kinase Nham_0518 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 92116931 Common - ISGsu2, transposase Nham_1376 38 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117540 Common - Thymidylate kinase Nham_2010 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 92119115 Common - Cupin 2, conserved barrel Nham_3656 21 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 92117578 Common - Invasion associated locus B Nham_2049 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 92117267 Nonpathogen - hypothetical protein Nham_1720 5 None None None 92119057 Common - oxidoreductase, molybdopterin binding Nham_3598 130 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 92116085 Common recR recombination protein RecR Nham_0464 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 92117811 Nonpathogen - hypothetical protein Nham_2288 1 None None None 92119130 Common - Twin-arginine translocation pathway signal Nham_3671 112 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 92119090 Common - protein of unknown function DUF488 Nham_3631 78 COG3189 COG3189, Uncharacterized conserved protein Function unknown 92117475 Common - transposase IS116/IS110/IS902 Nham_1939 86 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116511 Common - beta-lactamase-like Nham_0922 78 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 92116688 Common - FeoA Nham_1110 14 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 92118173 Common - hypothetical protein Nham_2663 72 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 92118789 Common - phage tail sheath protein Nham_3326 39 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 92116529 Nonpathogen - hypothetical protein Nham_0942 4 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 92117549 Common - phage Terminase Nham_2020 46 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 92117283 Nonpathogen secG preprotein translocase subunit SecG Nham_1737 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 92117639 Common aspS aspartyl-tRNA synthetase Nham_2111 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92117002 Common - periplasmic sensor signal transduction histidine kinase Nham_1449 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92116173 Common - hypothetical protein Nham_0552 88 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 92117955 Common - polysaccharide deacetylase Nham_2434 93 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 92118423 Common - hypothetical protein Nham_2925 38 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92117291 Common - hypothetical protein Nham_1745 15 None None None 92118472 Common - NapD-like protein Nham_2981 26 None None None 92116094 Common - membrane-flanked domain Nham_0473 17 COG3428 COG3428, Predicted membrane protein Function unknown 92117282 Common - Triosephosphate isomerase Nham_1736 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 92118655 Common - glycosyl transferase, family 2 Nham_3189 181 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92118487 Nonpathogen - hypothetical protein Nham_3003 1 None None None 92117024 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Nham_1471 36 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 92117522 Nonpathogen - hypothetical protein Nham_1992 1 None None None 92118342 Common - Helicase RecD/TraA Nham_2841 155 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 92115762 Common - Mg chelatase-related protein Nham_0130 198 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 92117700 Nonpathogen - hypothetical protein Nham_2176 3 None None None 92119139 Common - ErfK/YbiS/YcfS/YnhG Nham_3680 88 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92116609 Common - peptidase S1 and S6, chymotrypsin/Hap Nham_1030 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92117883 Nonpathogen - hypothetical protein Nham_2360 2 None None None 92115704 Common - protein of unknown function DUF71, ATP-binding region Nham_0072 35 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 92117648 Common - cold-shock DNA-binding domain protein Nham_2120 175 COG1278 CspC, Cold shock proteins Transcription 92116498 Nonpathogen - hypothetical protein Nham_0909 6 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 92116362 Common - Biopolymer transport protein ExbD/TolR Nham_0748 135 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 92115828 Common - Heparinase II/III-like Nham_0196 44 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 92115889 Nonpathogen - CoxF protein Nham_0258 5 None None None 92118324 Nonpathogen - hypothetical protein Nham_2822 5 None None None 92119087 Common - protein of unknown function DUF1232 Nham_3628 41 COG3339 COG3339, Uncharacterized conserved protein Function unknown 92118581 Common - transposase, IS4 Nham_3113 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116961 Common - protein of unknown function DUF264 Nham_1408 26 COG5323 COG5323, Uncharacterized conserved protein Function unknown 92118403 Nonpathogen - putative bacterioferritin Nham_2904 6 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 92116483 Common - formate acetyltransferase Nham_0889 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 92115678 Common - UBA/THIF-type NAD/FAD binding fold Nham_0046 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 92115652 Common - ribosomal-protein-alanine acetyltransferase Nham_0019 81 COG0456 RimI, Acetyltransferases General function prediction only 92116202 Common - hypothetical protein Nham_0581 16 None None None 92117384 Common - two component, sigma54 specific, transcriptional regulator, Fis family Nham_1839 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92117972 Common - histidine triad (HIT) protein Nham_2451 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 92116250 Common - OmpA/MotB Nham_0631 165 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 92118888 Common - ABC-3 Nham_3427 183 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 92115666 Common truB tRNA pseudouridine synthase B Nham_0033 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 92115668 Common - polynucleotide phosphorylase/polyadenylase Nham_0035 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 92118845 Common - hypothetical protein Nham_3384 178 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 92116348 Common - Fimbrial assembly Nham_0734 14 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 92116465 Common - 3-oxoacid CoA-transferase, subunit A Nham_0868 93 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 92117872 Common - hypothetical protein Nham_2349 136 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 92118090 Common - hypothetical protein Nham_2577 7 None None None 92115676 Common - protein of unknown function DUF1058 Nham_0044 50 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 92119241 Nonpathogen - hypothetical protein Nham_3793 1 None None None 92118131 Nonpathogen - hypothetical protein Nham_2618 1 None None None 92118817 Common - protein of unknown function DUF955 Nham_3355 49 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 92118890 Nonpathogen - hypothetical protein Nham_3429 2 None None None 92117108 Common rplN 50S ribosomal protein L14 Nham_1555 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 92118101 Common - DSBA oxidoreductase Nham_2588 47 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 92118118 Common - ATPase associated with various cellular activities, AAA_5 Nham_2605 98 COG0714 COG0714, MoxR-like ATPases General function prediction only 92117813 Common - alanine racemase Nham_2290 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 92117547 Common - hypothetical protein Nham_2018 11 None None None 92118377 Common - DoxX Nham_2878 39 COG2259 COG2259, Predicted membrane protein Function unknown 92117336 Common - seryl-tRNA synthetase Nham_1791 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 92118940 Common - electron transfer flavoprotein, alpha subunit Nham_3480 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 92116708 Nonpathogen - hypothetical protein Nham_1130 4 None None None 92116576 Common - Glucan 1,4-alpha-glucosidase Nham_0995 22 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 92117566 Nonpathogen - hypothetical protein Nham_2037 1 None None None 92116875 Nonpathogen - Hpt domain protein Nham_1319 3 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 92116169 Common - lipolytic enzyme, G-D-S-L Nham_0548 93 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 92117299 Common - Sel1-like Nham_1754 83 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 92116233 Common - amine oxidase Nham_0613 31 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 92116053 Common - methionine aminopeptidase, type I Nham_0431 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 92118314 Common - transcriptional regulator, Crp/Fnr family Nham_2812 110 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92119030 Common - two-component response regulator Nham_3570 41 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92117478 Nonpathogen - hypothetical protein Nham_1942 3 None None None 92117473 Common - acyltransferase 3 Nham_1937 75 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 92117821 Common - hypothetical protein Nham_2298 56 COG3247 HdeD, Uncharacterized conserved protein Function unknown 92116028 Common - hypothetical protein Nham_0406 30 None None None 92116758 Nonpathogen - hypothetical protein Nham_1195 2 None None None 92119414 Common - ISSpo6, transposase orf A Nham_4014 19 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117264 Common - Phage portal protein, HK97 Nham_1717 51 COG4695 COG4695, Phage-related protein Function unknown 92116339 Common - filamentous haemagglutinin-like Nham_0725 115 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 92118417 Common - GCN5-related N-acetyltransferase Nham_2919 89 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 92117455 Common - Alcohol dehydrogenase GroES-like Nham_1916 201 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 92119040 Common - 16S rRNA processing protein RimM Nham_3580 184 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 92118138 Common - Fe-S metabolism associated SufE Nham_2625 92 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 92115706 Common pheS phenylalanyl-tRNA synthetase subunit alpha Nham_0074 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 92118052 Common - hypothetical protein Nham_2539 12 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 92115868 Common - heat shock protein HtpX Nham_0237 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 92117497 Nonpathogen - hypothetical protein Nham_1964 1 None None None 92118799 Common - hypothetical protein Nham_3336 14 COG5471 COG5471, Uncharacterized conserved protein Function unknown 92116455 Nonpathogen - transposase IS3/IS911 Nham_0856 1 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115712 Common - putative PAS/PAC sensor protein Nham_0080 124 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 92117192 Common - hypothetical protein Nham_1643 6 None None None 92118765 Common - hypothetical protein Nham_3300 12 COG5514 COG5514, Uncharacterized conserved protein Function unknown 92116970 Common - Phage conserved hypothetical protein, phiE125 gp8 Nham_1417 23 None None None 92116434 Common - AAA ATPase, central region Nham_0827 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 92118792 Common - hypothetical protein Nham_3329 5 None None None 92119080 Nonpathogen - hypothetical protein Nham_3621 1 COG5373 COG5373, Predicted membrane protein Function unknown 92118171 Nonpathogen - hypothetical protein Nham_2661 3 None None None 92119228 Nonpathogen - hypothetical protein Nham_3777 3 None None None 92118484 Common - transposase IS3/IS911 Nham_2997 11 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116571 Common - cytochrome c, class I Nham_0990 15 COG3258 COG3258, Cytochrome c Energy production and conversion 92116396 Nonpathogen - hypothetical protein Nham_0786 2 None None None 92116159 Nonpathogen - hypothetical protein Nham_0538 1 None None None 92118559 Common - ribose-phosphate pyrophosphokinase Nham_3091 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 92119366 Nonpathogen - hypothetical protein Nham_3958 1 None None None 92116119 Common - cobalt chelatase, pCobS small subunit Nham_0498 69 COG0714 COG0714, MoxR-like ATPases General function prediction only 92119343 Common - IstB-like ATP-binding protein Nham_3924 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92118595 Common - Formate dehydrogenase, gamma subunit Nham_3128 59 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 92119424 Nonpathogen - hypothetical protein Nham_4024 1 None None None 92116691 Nonpathogen - hypothetical protein Nham_1113 2 None None None 92117272 Common - hypothetical protein Nham_1725 4 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 92116808 Nonpathogen - Phasin 2 Nham_1250 9 COG5490 COG5490, Uncharacterized conserved protein Function unknown 92117010 Common - hypothetical protein Nham_1457 10 None None None 92118274 Common - glycosyl transferase, group 1 Nham_2765 123 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92118750 Common - cytochrome c biogenesis factor Nham_3285 14 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 92117160 Nonpathogen - hypothetical protein Nham_1610 1 None None None 92117131 Common - carboxyl transferase Nham_1579 210 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 92118428 Common - Transposase and inactivated derivatives-like Nham_2931 76 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116310 Common - protein of unknown function DUF1153 Nham_0692 27 None None None 92116803 Common - AsmA Nham_1245 49 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 92118083 Common - cytochrome B561 Nham_2570 89 COG3038 CybB, Cytochrome B561 Energy production and conversion 92119317 Common - cytochrome B561 Nham_3894 77 COG3038 CybB, Cytochrome B561 Energy production and conversion 92116614 Nonpathogen - hypothetical protein Nham_1035 1 None None None 92118125 Common - inner-membrane translocator Nham_2612 125 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 92117355 Common - hypothetical protein Nham_1810 22 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 92115958 Nonpathogen - hypothetical protein Nham_0331 1 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 92118624 Common - diguanylate phosphodiesterase (EAL domain) Nham_3158 108 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 92117019 Common - alpha amylase, catalytic region Nham_1466 78 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 92117718 Common - ABC transporter related Nham_2195 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 92118457 Common - nitrate reductase, alpha subunit Nham_2961 96 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 92116766 Nonpathogen - Twin-arginine translocation pathway signal Nham_1206 11 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 92116531 Common - transcriptional regulator, ArsR family Nham_0944 118 COG0640 ArsR, Predicted transcriptional regulators Transcription 92117778 Common - (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA Nham_2255 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 92117397 Nonpathogen - hypothetical protein Nham_1852 8 None None None 92115983 Common - ABC transporter related Nham_0356 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92118532 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Nham_3055 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 92119157 Common - acetylglutamate kinase Nham_3700 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 92116623 Common - para-aminobenzoate synthase, component I Nham_1044 232 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 92118870 Common - putative transcriptional regulator, ModE family Nham_3409 91 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 92119142 Common - two component transcriptional regulator, winged helix family Nham_3683 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92117242 Common tsf elongation factor Ts Nham_1695 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 92116225 Common - protein of unknown function DUF1332 Nham_0605 37 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 92116445 Common - Catalase Nham_0843 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 92116983 Nonpathogen - hypothetical protein Nham_1430 1 None None None 92115855 Common hslO Hsp33-like chaperonin Nham_0224 115 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 92116722 Common - Recombinase Nham_1145 135 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92117334 Common - twin-arginine translocation protein TatB Nham_1789 41 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 92116363 Common - TonB-like Nham_0749 9 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 92118877 Common - hypothetical protein Nham_3416 21 COG3686 COG3686, Predicted membrane protein Function unknown 92117361 Common - riboflavin biosynthesis protein RibD Nham_1816 230 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 92116351 Nonpathogen - General secretion pathway protein I Nham_0737 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 92117324 Common - glycosyl transferase, family 2 Nham_1779 117 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 92119023 Common - sulfate adenylyltransferase subunit 2 Nham_3563 137 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 92116789 Common - hypothetical protein Nham_1230 4 None None None 92119427 Common - plasmid maintenance system killer Nham_4028 57 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 92118744 Common - secretion protein HlyD Nham_3279 154 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92117065 Nonpathogen - hypothetical protein Nham_1512 3 None None None 92118673 Nonpathogen - hypothetical protein Nham_3207 1 None None None 92117573 Common - Alcohol dehydrogenase, zinc-binding Nham_2044 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 92116749 Common - Twin-arginine translocation pathway signal Nham_1181 112 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 92119172 Common - IstB-like ATP-binding protein Nham_3715 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92116897 Nonpathogen - hypothetical protein Nham_1342 5 None None None 92119070 Common - secretion protein HlyD Nham_3611 110 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92117681 Common - virulence-associated E Nham_2155 33 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 92117892 Common - glycosyl transferase, group 1 Nham_2369 109 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92117793 Nonpathogen - hypothetical protein Nham_2270 1 None None None 92117727 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Nham_2204 87 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 92117947 Nonpathogen - hypothetical protein Nham_2426 4 None None None 92119303 Nonpathogen - hypothetical protein Nham_3874 1 None None None 92117855 Common - tyrosyl-tRNA synthetase Nham_2332 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92116734 Common - hypothetical protein Nham_1158 8 None None None 92118560 Common - hypothetical protein Nham_3092 8 None None None 92118235 Common - Peptidase S1C, Do Nham_2725 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92117590 Common - hypothetical protein Nham_2062 30 COG3148 COG3148, Uncharacterized conserved protein Function unknown 92116941 Common - hypothetical protein Nham_1388 25 COG3334 COG3334, Uncharacterized conserved protein Function unknown 92116828 Common - hypothetical protein Nham_1272 23 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 92118739 Common - Cof protein Nham_3274 127 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 92115981 Common - methyl-accepting chemotaxis sensory transducer Nham_0354 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 92118606 Common - branched-chain amino acid aminotransferase Nham_3139 210 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 92117251 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Nham_1704 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 92116062 Common - HPr kinase Nham_0441 26 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 92116673 Common - cytochrome c, class I Nham_1094 27 COG3258 COG3258, Cytochrome c Energy production and conversion 92118490 Common - transposase IS116/IS110/IS902 Nham_3007 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117754 Common - Twin-arginine translocation pathway signal Nham_2231 35 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 92116798 Common - protein of unknown function DUF465 Nham_1239 17 COG5570 COG5570, Uncharacterized small protein Function unknown 92117155 Nonpathogen - hypothetical protein Nham_1604 2 None None None 92115880 Common - transcriptional regulator, MarR family Nham_0249 36 COG1846 MarR, Transcriptional regulators Transcription 92118762 Common - secretion protein HlyD Nham_3297 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92117135 Common - Ubiquinol-cytochrome C chaperone Nham_1583 23 COG5452 COG5452, Uncharacterized conserved protein Function unknown 92118787 Nonpathogen - hypothetical protein Nham_3324 1 None None None 92116999 Nonpathogen - hypothetical protein Nham_1446 1 None None None 92116195 Common - antirestriction protein Nham_0574 50 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 92116742 Common - putative cold-shock DNA-binding domain protein Nham_1169 14 COG1278 CspC, Cold shock proteins Transcription 92115921 Common - phage integrase Nham_0294 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 92119419 Common - glycine cleavage T protein (aminomethyl transferase) Nham_4019 128 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 92118448 Common - putative transcriptional regulator, ModE family Nham_2952 91 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 92117060 Nonpathogen - hypothetical protein Nham_1507 3 None None None 92116214 Common - hypothetical protein Nham_0594 2 None None None 92116035 Common - periplasmic protein thiol Nham_0413 153 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 92118396 Nonpathogen - hypothetical protein Nham_2897 1 None None None 92117500 Nonpathogen - hypothetical protein Nham_1967 1 None None None 92116870 Common - mandelate racemase/muconate lactonizing enzyme Nham_1314 117 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 92119178 Nonpathogen - hypothetical protein Nham_3722 3 None None None 92117988 Common - hypothetical protein Nham_2467 12 None None None 92118306 Common - Serine--glyoxylate transaminase Nham_2804 153 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 92118038 Nonpathogen - hypothetical protein Nham_2525 1 None None None 92116330 Nonpathogen - hypothetical protein Nham_0714 3 None None None 92117671 Nonpathogen - hypothetical protein Nham_2144 1 None None None 92116536 Nonpathogen - hypothetical protein Nham_0950 1 None None None 92118286 Common - ABC-2 Nham_2778 84 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 92118569 Common - translation-associated GTPase Nham_3101 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 92117773 Common era GTP-binding protein Era Nham_2250 233 COG1159 Era, GTPase General function prediction only 92117619 Common - hypothetical protein Nham_2091 11 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 92115934 Nonpathogen - hypothetical protein Nham_0307 1 None None None 92116888 Nonpathogen - hypothetical protein Nham_1333 8 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 92118831 Common fliI flagellum-specific ATP synthase Nham_3370 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 92118189 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Nham_2679 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 92115995 Common - hypothetical protein Nham_0368 4 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 92116059 Common - GTP-binding protein LepA Nham_0438 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 92118064 Common - hypothetical protein Nham_2551 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 92116397 Common - IstB-like ATP-binding protein Nham_0788 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92116376 Common - short-chain dehydrogenase/reductase SDR Nham_0764 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 92116994 Common - Peptidase S1C, Do Nham_1441 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92117232 Common - hypothetical protein Nham_1684 25 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 92118370 Common - carbamoyl phosphate synthase small subunit Nham_2871 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 92117382 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Nham_1837 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92117926 Nonpathogen - hypothetical protein Nham_2404 3 None None None 92116186 Common - HemY-like Nham_0565 27 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 92117531 Common - hypothetical protein Nham_2001 29 None None None 92117079 Common nusG transcription antitermination protein NusG Nham_1526 215 COG0250 NusG, Transcription antiterminator Transcription 92117438 Common - phosphoribosylpyrophosphate synthetase Nham_1899 243 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 92117116 Common rpmD 50S ribosomal protein L30 Nham_1563 98 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 92117431 Nonpathogen - hypothetical protein Nham_1890 2 None None None 92115946 Common - IstB-like ATP-binding protein Nham_0319 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92117585 Common - protein of unknown function DUF502 Nham_2056 78 COG2928 COG2928, Uncharacterized conserved protein Function unknown 92117318 Common - cysteine synthases Nham_1773 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 92117151 Common - hypothetical protein Nham_1600 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119296 Common - hypothetical protein Nham_3862 3 None None None 92116043 Nonpathogen - hypothetical protein Nham_0421 1 None None None 92117552 Common - HNH nuclease / phage PHI-105 holin-like protein Nham_2023 4 None None None 92118292 Common - IstB-like ATP-binding protein Nham_2786 91 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92117429 Common - secretion protein HlyD Nham_1888 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92118545 Nonpathogen - hypothetical protein Nham_3074 1 None None None 92119308 Nonpathogen - hypothetical protein Nham_3879 2 None None None 92118810 Common - hypothetical protein Nham_3348 9 None None None 92118668 Common - protein of unknown function DUF224, cysteine-rich region Nham_3202 164 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 92118780 Common - hypothetical protein Nham_3317 8 None None None 92117206 Common hisI phosphoribosyl-AMP cyclohydrolase Nham_1658 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 92118498 Nonpathogen - hypothetical protein Nham_3021 2 None None None 92118994 Common - Fructose-bisphosphate aldolase Nham_3534 35 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 92118999 Common - secretion protein HlyD Nham_3539 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92118233 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Nham_2723 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 92115928 Common - hypothetical protein Nham_0301 3 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 92117908 Common - hypothetical protein Nham_2386 2 None None None 92116591 Common - phage Tail Collar Nham_1012 37 COG4675 MdpB, Microcystin-dependent protein Function unknown 92118456 Common - ThiJ/PfpI Nham_2960 76 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 92119035 Common dapF diaminopimelate epimerase Nham_3575 190 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 92119026 Nonpathogen - hypothetical protein Nham_3566 1 None None None 92118634 Common - tISRso5; ISRSO5-transposase protein Nham_3168 47 None None None 92117211 Common ppnK inorganic polyphosphate/ATP-NAD kinase Nham_1663 189 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 92118502 Common - Type I secretion membrane fusion protein, HlyD Nham_3025 122 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92118513 Common - NAD-dependent epimerase/dehydratase Nham_3036 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92118550 Common - transposase IS116/IS110/IS902 Nham_3079 81 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119289 Common - protein of unknown function DUF1130 Nham_3855 50 COG5483 COG5483, Uncharacterized conserved protein Function unknown 92115771 Common - hypothetical protein Nham_0139 5 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 92117993 Nonpathogen - hypothetical protein Nham_2472 2 None None None 92115721 Common - aminotransferase, class I and II Nham_0089 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 92117357 Common - hypothetical protein Nham_1812 17 None None None 92119077 Common sdhA succinate dehydrogenase flavoprotein subunit Nham_3618 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 92116656 Common - SlyX Nham_1077 25 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 92116815 Common - hypothetical protein Nham_1257 16 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 92117054 Common - extracellular solute-binding protein, family 1 Nham_1501 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 92118759 Common - periplasmic sensor signal transduction histidine kinase Nham_3294 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92118855 Common - Twin-arginine translocation pathway signal Nham_3394 93 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 92117112 Common rpsH 30S ribosomal protein S8 Nham_1559 240 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 92118333 Common - metallophosphoesterase Nham_2831 67 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 92118145 Common - dihydropteroate synthase Nham_2633 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 92116383 Common clpS ATP-dependent Clp protease adaptor Nham_0771 120 COG2127 COG2127, Uncharacterized conserved protein Function unknown 92117243 Common - Uridylate kinase Nham_1696 247 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 92119340 Nonpathogen - hypothetical protein Nham_3920 5 None None None 92117311 Common coaD phosphopantetheine adenylyltransferase Nham_1766 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 92118576 Common - Transketolase, central region Nham_3108 220 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 92116647 Nonpathogen - hypothetical protein Nham_1068 1 None None None 92117539 Common - DNA polymerase III subunit delta' Nham_2009 219 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 92117592 Common - acriflavin resistance protein Nham_2064 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92118167 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Nham_2657 145 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 92118071 Common - acyl-CoA dehydrogenase-like Nham_2558 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92116476 Nonpathogen - hypothetical protein Nham_0881 2 None None None 92116324 Common - DoxX Nham_0708 23 COG2259 COG2259, Predicted membrane protein Function unknown 92116844 Common - putative lipoprotein Nham_1288 128 COG4105 ComL, DNA uptake lipoprotein General function prediction only 92117124 Common - Peptidase S1C, Do Nham_1572 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92117659 Nonpathogen - hypothetical protein Nham_2131 2 None None None 92116837 Nonpathogen - hypothetical protein Nham_1281 6 None None None 92118516 Common - polysaccharide biosynthesis protein Nham_3039 80 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 92118436 Nonpathogen - hypothetical protein Nham_2939 1 None None None 92117533 Common - hypothetical protein Nham_2003 30 None None None 92117723 Common - protein of unknown function DUF461 Nham_2200 83 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 92119199 Common - homoserine kinase Nham_3744 64 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 92117092 Nonpathogen - hypothetical protein Nham_1539 1 None None None 92117442 Common - nitroreductase Nham_1903 57 COG0778 NfnB, Nitroreductase Energy production and conversion 92118812 Nonpathogen - hypothetical protein Nham_3350 1 None None None 92115655 Common - PhoH-like protein Nham_0022 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 92117006 Common - (2Fe-2S)-binding Nham_1453 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 92118363 Common - Twin-arginine translocation pathway signal Nham_2864 56 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92116541 Common - TonB-dependent receptor Nham_0957 73 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 92118547 Common - transposase Nham_3076 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 92118529 Common - glucose-1-phosphate thymidylyltransferase Nham_3052 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 92118352 Common - hypothetical protein Nham_2853 9 None None None 92119282 Nonpathogen - hypothetical protein Nham_3848 1 None None None 92118217 Nonpathogen - hypothetical protein Nham_2707 1 None None None 92117601 Common - Na/Pi cotransporter II-related Nham_2073 85 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 92117939 Common - hypothetical protein Nham_2418 20 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 92117225 Common - protein of unknown function DUF47 Nham_1677 69 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 92116014 Common - Flp pilus assembly CpaB Nham_0392 58 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 92116795 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Nham_1236 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 92115900 Common - F0F1 ATP synthase subunit A Nham_0269 146 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 92118321 Common - quinolinate synthetase Nham_2819 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 92116780 Common - hypothetical protein Nham_1221 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 92116813 Common - polysaccharide deacetylase Nham_1255 98 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 92118522 Common - glycosyl transferase, family 2 Nham_3045 177 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92116283 Common - hypothetical protein Nham_0664 29 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 92118530 Common - dTDP-4-dehydrorhamnose reductase Nham_3053 168 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 92116936 Common flgG flagellar basal body rod protein FlgG Nham_1383 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 92117195 Common - hypothetical protein Nham_1646 13 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 92116369 Common - transcriptional regulator, LysR family Nham_0756 155 COG0583 LysR, Transcriptional regulator Transcription 92115816 Common - undecaprenyl pyrophosphate phosphatase Nham_0184 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 92116117 Common - heat shock protein DnaJ-like Nham_0496 43 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 92117099 Common rplD 50S ribosomal protein L4 Nham_1546 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 92117901 Nonpathogen - hypothetical protein Nham_2379 4 None None None 92118974 Common - Biopolymer transport protein ExbD/TolR Nham_3514 138 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 92119049 Common - protein of unknown function DUF1025 Nham_3590 39 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 92117278 Common moaC molybdenum cofactor biosynthesis protein C Nham_1732 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 92118920 Nonpathogen - CoxF protein Nham_3460 5 None None None 92118707 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit Nham_3241 106 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 92118359 Common - RNA polymerase factor sigma-32 Nham_2860 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 92117394 Common - Secretion protein HlyD Nham_1849 143 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92118276 Common - Nucleotidyl transferase Nham_2767 161 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 92115871 Common - DEAD/DEAH box helicase-like Nham_0240 162 COG1201 Lhr, Lhr-like helicases General function prediction only 92116413 Common - Catalase Nham_0804 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 92117982 Nonpathogen - hypothetical protein Nham_2461 6 None None None 92116532 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Nham_0945 224 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 92117751 Common clpX ATP-dependent protease ATP-binding subunit Nham_2228 226 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 92116385 Common - transcriptional regulator, ArsR family Nham_0774 119 COG0640 ArsR, Predicted transcriptional regulators Transcription 92116041 Common - PRC-barrel Nham_0419 29 None None None 92117839 Nonpathogen - hypothetical protein Nham_2316 7 None None None 92116946 Common flgC flagellar basal body rod protein FlgC Nham_1393 125 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 92115909 Nonpathogen - hypothetical protein Nham_0280 1 None None None 92115701 Common - hypothetical protein Nham_0069 35 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 92118835 Common - response regulator receiver domain protein (CheY-like) Nham_3374 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 92117962 Common rpmG 50S ribosomal protein L33 Nham_2441 123 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 92119187 Common - alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen Nham_3732 82 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 92118381 Common - Cobyrinic acid a,c-diamide synthase Nham_2882 151 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 92116156 Common - primosome assembly protein PriA Nham_0535 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 92118841 Common - Uncharacterised conserved protein UCP033924 Nham_3380 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 92118477 Common - plasmid pRiA4b ORF-3-like Nham_2989 44 None None None 92117931 Nonpathogen - hypothetical protein Nham_2409 1 None None None 92118248 Nonpathogen - protein of unknown function DUF1328 Nham_2738 1 COG5487 COG5487, Small integral membrane protein Function unknown 92117847 Common - protein of unknown function DUF59 Nham_2324 111 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 92116246 Nonpathogen - hypothetical protein Nham_0627 3 None None None 92118700 Common - peptidase M48, Ste24p Nham_3234 179 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 92116418 Nonpathogen - hypothetical protein Nham_0811 5 None None None 92116334 Common - ABC transporter related Nham_0718 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 92116881 Nonpathogen - hypothetical protein Nham_1326 5 None None None 92116894 Nonpathogen - hypothetical protein Nham_1339 3 None None None 92117922 Nonpathogen - hypothetical protein Nham_2400 4 None None None 92118933 Common - protein of unknown function DUF59 Nham_3473 143 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 92118068 Common - AMP-dependent synthetase and ligase Nham_2555 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 92118928 Common - cobalamin synthesis protein, P47K Nham_3468 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 92117280 Common trpD anthranilate phosphoribosyltransferase Nham_1734 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 92118042 Common - phage integrase Nham_2529 27 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92117200 Common - hypothetical protein Nham_1651 13 None None None 92118539 Common - sugar transferase Nham_3064 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 92117742 Common - NADH dehydrogenase subunit C Nham_2219 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 92116261 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Nham_0642 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 92115852 Common - hypothetical protein Nham_0221 9 None None None 92116451 Common - alpha/beta hydrolase fold Nham_0851 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 92116297 Common - hypothetical protein Nham_0679 5 None None None 92118585 Common - 4Fe-4S ferredoxin, iron-sulfur binding Nham_3118 59 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 92116709 Common - UTP-glucose-1-phosphate uridylyltransferase Nham_1131 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 92119355 Common - transposase IS116/IS110/IS902 Nham_3943 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116268 Nonpathogen - hypothetical protein Nham_0649 2 None None None 92117401 Nonpathogen - hypothetical protein Nham_1856 1 COG1777 COG1777, Predicted transcriptional regulators Transcription 92118892 Nonpathogen - hypothetical protein Nham_3431 1 None None None 92116606 Common - hypothetical protein Nham_1027 14 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 92117269 Common - HNH nuclease / phage PHI-105 holin-like protein Nham_1722 5 None None None 92117408 Nonpathogen - hypothetical protein Nham_1863 3 None None None 92119430 Common - hypothetical protein Nham_4032 21 COG3177 COG3177, Uncharacterized conserved protein Function unknown 92118288 Common - GDP-mannose 4,6-dehydratase Nham_2780 216 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 92116315 Nonpathogen - hypothetical protein Nham_0697 4 None None None 92117217 Common thrS threonyl-tRNA synthetase Nham_1669 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92117917 Nonpathogen - hypothetical protein Nham_2395 3 None None None 92115803 Common - PTS IIA-like nitrogen-regulatory protein PtsN Nham_0171 130 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 92115650 Common - hypothetical protein Nham_0017 11 None None None 92119059 Common - malonyl-CoA synthase Nham_3600 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92118467 Common - sulfatase Nham_2976 70 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 92116171 Common - protein of unknown function DUF214 Nham_0550 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 92115847 Nonpathogen - hypothetical protein Nham_0216 2 None None None 92117977 Common - Phenylacetic acid degradation-related protein Nham_2456 33 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 92116916 Common - AAA ATPase, central region Nham_1361 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 92118622 Common - TadE-like Nham_3156 7 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 92118775 Nonpathogen - hypothetical protein Nham_3312 1 None None None 92115785 Common - GrpE protein Nham_0153 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 92116504 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Nham_0915 4 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 92118227 Common - hypothetical protein Nham_2717 11 None None None 92118300 Common - phage integrase-like SAM-like Nham_2797 17 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92117036 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Nham_1483 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 92117654 Common - ETC complex I subunit conserved region Nham_2126 36 None None None 92118032 Nonpathogen - hypothetical protein Nham_2519 1 None None None 92119275 Common - hypothetical protein Nham_3841 18 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 92116685 Common - transcriptional regulator, XRE family Nham_1107 14 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 92118183 Common - blue (type 1) copper domain Nham_2673 30 COG3794 PetE, Plastocyanin Energy production and conversion 92116090 Common - modification methylase, HemK family Nham_0469 220 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 92117477 Common - cytochrome B561 Nham_1941 54 COG3038 CybB, Cytochrome B561 Energy production and conversion 92117342 Common - protein of unknown function DUF815 Nham_1797 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 92118340 Common - SNF2-related Nham_2839 150 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 92118197 Nonpathogen - hypothetical protein Nham_2687 4 None None None 92118971 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Nham_3511 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 92117694 Common - Alcohol dehydrogenase, zinc-binding Nham_2168 207 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 92119188 Common - protein of unknown function DUF924 Nham_3733 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 92117289 Common - Phosphopyruvate hydratase Nham_1743 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 92117979 Common - O-acetylhomoserine aminocarboxypropyltransferase Nham_2458 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 92119117 Nonpathogen - hypothetical protein Nham_3658 1 None None None 92116092 Common - PTSINtr with GAF domain, PtsP Nham_0471 221 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 92118421 Common - excinuclease ABC subunit B Nham_2923 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 92117784 Common - large conductance mechanosensitive channel protein Nham_2261 126 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 92116704 Common - hypothetical protein Nham_1126 33 None None None 92117000 Common - periplasmic sensor signal transduction histidine kinase Nham_1447 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92117695 Common - adenylate/guanylate cyclase Nham_2169 83 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 92116920 Nonpathogen - hypothetical protein Nham_1365 3 None None None 92116275 Common - short-chain dehydrogenase/reductase SDR Nham_0656 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 92117970 Common - glycerophosphoryl diester phosphodiesterase Nham_2449 63 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 92118485 Common - transposase, IS4 Nham_2998 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118950 Common - HNH endonuclease Nham_3490 98 COG1403 McrA, Restriction endonuclease Defense mechanisms 92116427 Nonpathogen - hypothetical protein Nham_0820 24 None None None 92118988 Common - 5-formyltetrahydrofolate cyclo-ligase Nham_3528 184 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 92117968 Common - tISRso5; ISRSO5-transposase protein Nham_2447 47 None None None 92118865 Common - hypothetical protein Nham_3404 13 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 92117425 Nonpathogen - Propeptide, PepSY amd peptidase M4 Nham_1884 13 COG3212 COG3212, Predicted membrane protein Function unknown 92119092 Common - PepSY-associated TM helix Nham_3633 29 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 92116900 Nonpathogen fliX flagellar assembly regulator FliX Nham_1345 6 None None None 92115826 Common - cytochrome c, class I Nham_0194 63 COG2863 COG2863, Cytochrome c553 Energy production and conversion 92116736 Nonpathogen - hypothetical protein Nham_1161 4 None None None 92117174 Common - RNA methyltransferase TrmH, group 1 Nham_1624 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 92116360 Common - TonB-dependent siderophore receptor Nham_0746 87 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92117936 Common rplI 50S ribosomal protein L9 Nham_2415 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 92119334 Common - Integrase, catalytic region Nham_3914 80 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117903 Common - Phage tail protein I Nham_2381 26 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 92117450 Common - hypothetical protein Nham_1911 10 None None None 92118583 Nonpathogen - hypothetical protein Nham_3115 1 None None None 92117045 Common - ABC transporter related Nham_1492 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 92116739 Common - signal transduction histidine kinase Nham_1165 87 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92117386 Common hfq RNA-binding protein Hfq Nham_1841 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 92117989 Common - Saccharopine dehydrogenase Nham_2468 46 COG3268 COG3268, Uncharacterized conserved protein Function unknown 92117581 Nonpathogen - hypothetical protein Nham_2052 3 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 92118968 Common - TPR repeat protein Nham_3508 63 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 92118201 Common - phosphoenolpyruvate carboxylase Nham_2691 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 92115970 Common - RecA-family ATPase-like Nham_0343 23 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 92118496 Common - transposase, mutator type Nham_3015 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115790 Common - dihydrodipicolinate reductase Nham_0158 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 92116005 Common - NLP/P60 Nham_0383 84 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 92118413 Nonpathogen - hypothetical protein Nham_2915 3 COG5373 COG5373, Predicted membrane protein Function unknown 92117493 Common - hypothetical protein Nham_1960 49 None None None 92117794 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Nham_2271 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 92119363 Common - transposase IS116/IS110/IS902 Nham_3955 78 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117009 Common - hypothetical protein Nham_1456 26 COG4309 COG4309, Uncharacterized conserved protein Function unknown 92117447 Nonpathogen - hypothetical protein Nham_1908 1 None None None 92117605 Common - Penicillin-binding protein 1C Nham_2077 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 92117645 Common - CDP-alcohol phosphatidyltransferase Nham_2117 94 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 92119321 Nonpathogen - hypothetical protein Nham_3898 1 None None None 92117707 Common - aminotransferase, class I and II Nham_2183 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 92117849 Common - FeS assembly protein SufD Nham_2326 176 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 92117260 Nonpathogen - hypothetical protein Nham_1713 1 None None None 92117851 Common - cysteine desulfurase activator complex subunit SufB Nham_2328 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 92116272 Common - hypothetical protein Nham_0653 12 None None None 92118979 Common - 3-demethylubiquinone-9 3-methyltransferase Nham_3519 67 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 92118155 Nonpathogen - Twin-arginine translocation pathway signal Nham_2643 1 None None None 92117626 Common - polyphosphate glucokinase Nham_2098 30 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 92115747 Common - DNA polymerase III, epsilon subunit Nham_0115 194 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 92118645 Common - protein of unknown function DUF374 Nham_3179 41 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 92117236 Common - orotidine 5'-phosphate decarboxylase Nham_1688 169 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 92117716 Common aat leucyl/phenylalanyl-tRNA--protein transferase Nham_2193 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 92116636 Common - UDP-glucose 6-dehydrogenase Nham_1057 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 92117462 Common - Mammalian cell entry related Nham_1923 64 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 92115731 Nonpathogen - hypothetical protein Nham_0099 4 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 92115818 Common - 2-dehydropantoate 2-reductase Nham_0186 98 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 92115697 Common - hypothetical protein Nham_0065 17 None None None 92116973 Common - gene transfer agent (GTA) like protein Nham_1420 10 None None None 92119403 Nonpathogen - hypothetical protein Nham_4002 2 None None None 92119378 Nonpathogen - hypothetical protein Nham_3972 4 None None None 92118253 Common - ErfK/YbiS/YcfS/YnhG Nham_2743 28 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92118003 Nonpathogen - hypothetical protein Nham_2482 3 None None None 92118653 Common hisZ ATP phosphoribosyltransferase regulatory subunit Nham_3187 117 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 92116320 Common - protein of unknown function DUF155 Nham_0703 18 COG1723 COG1723, Uncharacterized conserved protein Function unknown 92116568 Common - hypothetical protein Nham_0987 5 None None None 92119097 Common - TonB-dependent siderophore receptor Nham_3638 89 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92116600 Common - FAD dependent oxidoreductase Nham_1021 30 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 92116772 Common - signal transduction histidine kinase Nham_1213 123 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92118021 Nonpathogen - hypothetical protein Nham_2504 2 None None None 92118441 Nonpathogen - hypothetical protein Nham_2944 1 None None None 92118347 Common - hypothetical protein Nham_2848 4 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 92118178 Common - hypothetical protein Nham_2668 23 COG4544 COG4544, Uncharacterized conserved protein Function unknown 92118613 Common uvrC excinuclease ABC subunit C Nham_3146 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 92116561 Common - hypothetical protein Nham_0979 13 COG4274 COG4274, Uncharacterized conserved protein Function unknown 92118670 Common - FAD linked oxidase-like Nham_3204 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 92116259 Common - two component transcriptional regulator, winged helix family Nham_0640 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92118111 Common - Dolichyl-phosphate beta-D-mannosyltransferase Nham_2598 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92119390 Nonpathogen - hypothetical protein Nham_3987 1 None None None 92117512 Common - metallophosphoesterase Nham_1981 33 COG1409 Icc, Predicted phosphohydrolases General function prediction only 92119352 Nonpathogen - hypothetical protein Nham_3940 2 None None None 92119326 Common ligC ATP-dependent DNA ligase Nham_3905 106 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 92116968 Common - phage major capsid protein, HK97 Nham_1415 54 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 92117576 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase Nham_2047 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 92115972 Common - protein of unknown function DUF214 Nham_0345 44 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 92116693 Common - major facilitator superfamily MFS_1 Nham_1115 148 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92118599 Common - formate dehydrogenase family accessory protein FdhD Nham_3132 135 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 92117240 Common dnaE DNA polymerase III subunit alpha Nham_1693 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 92118108 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Nham_2595 51 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 92118127 Common - ABC transporter related Nham_2614 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92119014 Common - 3-hydroxybutyrate dehydrogenase Nham_3554 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 92117274 Common - phage integrase Nham_1727 174 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92116023 Common - pseudouridine synthase Nham_0401 214 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 92116719 Common - N-formylglutamate amidohydrolase Nham_1142 59 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 92118059 Common - inositol-5-monophosphate dehydrogenase Nham_2546 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 92118593 Common - Twin-arginine translocation pathway signal Nham_3126 189 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 92116453 Common - hypothetical protein Nham_0853 50 COG3832 COG3832, Uncharacterized conserved protein Function unknown 92119315 Nonpathogen - hypothetical protein Nham_3890 2 None None None 92117670 Nonpathogen - hypothetical protein Nham_2143 1 None None None 92115944 Nonpathogen - hypothetical protein Nham_0317 1 None None None 92117133 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Nham_1581 186 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 92118752 Common - molybdopterin oxidoreductase Nham_3287 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 92118682 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Nham_3216 173 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 92116850 Common - Lipopolysaccharide heptosyltransferase I Nham_1294 96 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 92115755 Common - hypothetical protein Nham_0123 9 None None None 92118097 Common - monooxygenase, FAD-binding Nham_2584 115 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 92116580 Common - protein of unknown function DUF347 Nham_0999 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 92116805 Common - 3-oxoacid CoA-transferase, subunit B Nham_1247 101 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 92116821 Common - transposase IS3/IS911 Nham_1263 33 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116986 Common - two component transcriptional regulator, winged helix family Nham_1433 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92118826 Common - phage integrase Nham_3365 16 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92117769 Common - transcriptional regulator, ArsR family Nham_2246 61 COG4189 COG4189, Predicted transcriptional regulator Transcription 92117137 Common - fatty acid/phospholipid synthesis protein Nham_1585 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 92116621 Nonpathogen - hypothetical protein Nham_1042 1 None None None 92116806 Nonpathogen - hypothetical protein Nham_1248 3 None None None 92115985 Common - Acetyl-CoA C-acyltransferase Nham_0358 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 92118224 Nonpathogen - hypothetical protein Nham_2714 5 None None None 92116227 Common - protein of unknown function YGGT Nham_0607 32 None None None 92116711 Common - hypothetical protein Nham_1133 24 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 92115728 Common - Protein of unknown function UPF0001 Nham_0096 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 92117449 Common - protein of unknown function DUF302 Nham_1910 40 COG3439 COG3439, Uncharacterized conserved protein Function unknown 92119306 Common - hypothetical protein Nham_3877 14 None None None 92117072 Common - peptidase M50 Nham_1519 87 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 92116764 Common - acylneuraminate cytidylyltransferase Nham_1201 27 COG1861 SpsF, Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog Cell envelope biogenesis, outer membrane 92116448 Common - transcriptional regulator, LysR family Nham_0847 108 COG0583 LysR, Transcriptional regulator Transcription 92117867 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Nham_2344 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 92118730 Common - protein of unknown function DUF486 Nham_3265 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 92118804 Nonpathogen - hypothetical protein Nham_3341 2 None None None 92118208 Common - D-amino-acid dehydrogenase Nham_2698 127 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 92118143 Common - protein of unknown function DUF853, NPT hydrolase putative Nham_2631 80 COG0433 COG0433, Predicted ATPase General function prediction only 92116628 Common - hemolysin-type calcium-binding region Nham_1049 91 None None None 92116654 Common - 2-nitropropane dioxygenase, NPD Nham_1075 128 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 92116669 Common glpD glycerol-3-phosphate dehydrogenase Nham_1090 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 92117399 Common - Heavy metal efflux pump CzcA Nham_1854 180 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 92118615 Common - cold-shock DNA-binding domain protein Nham_3148 178 COG1278 CspC, Cold shock proteins Transcription 92118454 Common - hypothetical protein Nham_2958 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 92117328 Nonpathogen - hypothetical protein Nham_1783 3 None None None 92117326 Common - putative beta (1-6) glucans synthase Nham_1781 15 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 92116724 Common - hypothetical protein Nham_1147 9 None None None 92116514 Nonpathogen - hypothetical protein Nham_0925 1 None None None 92117040 Nonpathogen - hypothetical protein Nham_1487 5 None None None 92117487 Common - transposase IS116/IS110/IS902 Nham_1954 60 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118879 Nonpathogen - hypothetical protein Nham_3418 3 None None None 92116485 Common - YidE/YbjL duplication Nham_0891 56 COG2985 COG2985, Predicted permease General function prediction only 92117664 Common - transposase orfA IS5 family element Nham_2136 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118307 Nonpathogen - hypothetical protein Nham_2805 3 None None None 92118723 Common - GCN5-related N-acetyltransferase Nham_3258 88 COG3153 COG3153, Predicted acetyltransferase General function prediction only 92116400 Nonpathogen - hypothetical protein Nham_0791 11 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 92119277 Common - transcriptional regulator, XRE family Nham_3843 23 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 92118431 Common - transposase IS116/IS110/IS902 Nham_2934 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118942 Common - ATP--cobalamin adenosyltransferase Nham_3482 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 92116312 Common - flagellar hook-length control protein Nham_0694 12 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 92116770 Nonpathogen - hypothetical protein Nham_1211 1 None None None 92115641 Common - protein of unknown function DUF1330 Nham_0008 43 COG5470 COG5470, Uncharacterized conserved protein Function unknown 92118853 Common - glycosyl transferase, family 39 Nham_3392 43 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 92117677 Common - peptidase U35, phage prohead HK97 Nham_2150 10 COG3740 COG3740, Phage head maturation protease General function prediction only 92119032 Common - RNA polymerase sigma factor Nham_3572 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92118415 Common - Rhodanese-like Nham_2917 71 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 92119150 Common - Peptide deformylase Nham_3693 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 92118742 Common - Alkylhydroperoxidase AhpD core Nham_3277 83 COG2128 COG2128, Uncharacterized conserved protein Function unknown 92119021 Common - phosphoadenosine phosphosulfate reductase Nham_3561 145 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 92115636 Common recF recombination protein F Nham_0003 112 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 92116177 Common - protein of unknown function DUF952 Nham_0556 43 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 92118133 Common - Ribulose-phosphate 3-epimerase Nham_2620 215 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 92116877 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Nham_1321 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 92119102 Common - Cytochrome-c oxidase Nham_3643 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 92117293 Common - NADPH-dependent FMN reductase Nham_1747 108 COG0431 COG0431, Predicted flavoprotein General function prediction only 92116589 Common - putative monovalent cation/H+ antiporter subunit C Nham_1009 85 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 92117194 Common - glutamate racemase Nham_1645 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 92117621 Nonpathogen - hypothetical protein Nham_2093 1 None None None 92116231 Common - GCN5-related N-acetyltransferase Nham_0611 40 COG0456 RimI, Acetyltransferases General function prediction only 92117114 Common rplR 50S ribosomal protein L18 Nham_1561 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 92116185 Common - hypothetical protein Nham_0564 9 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 92115966 Common - Phage portal protein, HK97 Nham_0339 52 COG4695 COG4695, Phage-related protein Function unknown 92116578 Common - periplasmic sensor signal transduction histidine kinase Nham_0997 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92116832 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase Nham_1276 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 92116220 Nonpathogen - hypothetical protein Nham_0600 4 None None None 92115674 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Nham_0042 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 92116857 Common - hypothetical protein Nham_1301 15 COG0392 COG0392, Predicted integral membrane protein Function unknown 92117169 Common - glycine cleavage system H protein Nham_1619 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 92117823 Common - Protein of unknown function DUF160 Nham_2300 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 92117502 Common - nuclease (SNase-like) Nham_1969 66 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 92116649 Common - transcriptional regulator, PadR-like family Nham_1070 53 COG1695 COG1695, Predicted transcriptional regulators Transcription 92116051 Nonpathogen - hypothetical protein Nham_0429 7 None None None 92116322 Common - sulphate transporter Nham_0705 151 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 92117888 Nonpathogen - hypothetical protein Nham_2365 1 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 92116662 Common - transcriptional regulator, TetR family Nham_1083 40 COG1309 AcrR, Transcriptional regulator Transcription 92119365 Nonpathogen - hypothetical protein Nham_3957 2 None None None 92118120 Common - (2Fe-2S)-binding Nham_2607 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 92116337 Common - Cupin 2, conserved barrel Nham_0721 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 92118728 Common - transposase orfA IS5 family element Nham_3263 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116544 Common - peptidase C14, caspase catalytic subunit p20 Nham_0960 15 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 92118482 Common - potassium-transporting ATPase subunit A Nham_2994 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 92116377 Common - pyridoxamine 5'-phosphate oxidase Nham_0765 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 92118050 Common - transcriptional regulator-related protein Nham_2537 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92116066 Common - phosphoenolpyruvate carboxykinase Nham_0445 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 92117316 Common tgt queuine tRNA-ribosyltransferase Nham_1771 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 92115643 Common - PfkB Nham_0010 186 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 92119377 Nonpathogen - hypothetical protein Nham_3971 2 None None None 92118794 Common - Baseplate J-like protein Nham_3331 32 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 92115765 Nonpathogen - hypothetical protein Nham_0133 3 None None None 92116706 Common - methionine sulfoxide reductase B Nham_1128 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 92118953 Common - hypothetical protein Nham_3493 41 COG2346 COG2346, Truncated hemoglobins General function prediction only 92118268 Common - transposase (class II) Nham_2759 39 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117725 Nonpathogen - hypothetical protein Nham_2202 3 None None None 92117885 Common - hypothetical protein Nham_2362 10 None None None 92119299 Common - Esterase, PHB depolymerase Nham_3867 31 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 92115710 Common - hypothetical protein Nham_0078 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 92119107 Common - ABC transporter related Nham_3648 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92116718 Common - Histidinol-phosphate phosphatase, putative, inositol monophosphatase Nham_1141 191 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 92117756 Common - nitrogen regulatory protein P-II (GlnB, GlnK) Nham_2233 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 92116432 Common - hypothetical protein Nham_0825 18 COG5373 COG5373, Predicted membrane protein Function unknown 92117495 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Nham_1962 12 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 92116033 Common - heme exporter protein CcmC Nham_0411 126 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 92116750 Common - (2Fe-2S)-binding Nham_1182 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 92118823 Nonpathogen - hypothetical protein Nham_3361 1 None None None 92117047 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Nham_1494 148 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 92118296 Common - TRm23a transposase Nham_2791 55 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118069 Common - 3-hydroxyisobutyrate dehydrogenase Nham_2556 186 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 92118557 Nonpathogen - hypothetical protein Nham_3089 1 None None None 92117014 Common - Malto-oligosyltrehalose synthase Nham_1461 105 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 92116399 Common - hypothetical protein Nham_0790 26 None None None 92116929 Common - cyclic nucleotide-binding domain (cNMP-BD) protein Nham_1374 144 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 92119270 Nonpathogen - hypothetical protein Nham_3836 1 None None None 92118702 Nonpathogen - hypothetical protein Nham_3236 3 None None None 92116370 Common - Pirin-like Nham_0757 146 COG1741 COG1741, Pirin-related protein General function prediction only 92116892 Common - hypothetical protein Nham_1337 40 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 92119384 Common - PRC-barrel Nham_3980 32 None None None 92117436 Common - putative signal-transduction protein with CBS domains Nham_1897 104 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 92118318 Common - 8-amino-7-oxononanoate synthase Nham_2816 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 92118935 Common - diaminopimelate decarboxylase Nham_3475 219 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 92117077 Nonpathogen - hypothetical protein Nham_1524 2 None None None 92119005 Common rpmE 50S ribosomal protein L31 Nham_3545 147 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 92116992 Common - cytochrome c-type biogenesis protein CcmF Nham_1439 141 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 92117038 Common nadE NAD synthetase Nham_1485 221 COG0171 NadE, NAD synthase Coenzyme metabolism 92116161 Nonpathogen - hypothetical protein Nham_0540 1 None None None 92118375 Common greA transcription elongation factor GreA Nham_2876 204 COG0782 GreA, Transcription elongation factor Transcription 92115825 Common - cytochrome c, class I Nham_0193 35 COG3258 COG3258, Cytochrome c Energy production and conversion 92119298 Common - Recombinase Nham_3864 88 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92118198 Common - putative RND superfamily transporter Nham_2688 62 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 92116204 Nonpathogen - hypothetical protein Nham_0584 1 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 92115910 Nonpathogen - hypothetical protein Nham_0281 1 None None None 92119140 Common - RNA polymerase sigma factor Nham_3681 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92118451 Common - transposase IS116/IS110/IS902 Nham_2955 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116128 Common - transcriptional regulator, CarD family Nham_0507 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 92118062 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Nham_2549 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 92116401 Common - sugar kinase-like protein Nham_0792 21 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 92116057 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Nham_0435 156 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 92119349 Nonpathogen - hypothetical protein Nham_3933 1 None None None 92118203 Common - cytochrome P450 Nham_2693 85 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 92118882 Common - GreA/GreB family elongation factor Nham_3421 88 COG0782 GreA, Transcription elongation factor Transcription 92116358 Common - hypothetical protein Nham_0744 26 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 92117760 Nonpathogen - hypothetical protein Nham_2237 1 None None None 92117899 Common - phage major tail tube protein Nham_2377 27 COG3498 COG3498, Phage tail tube protein FII General function prediction only 92117877 Common - malonyl CoA-acyl carrier protein transacylase Nham_2354 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 92117359 Common glyA serine hydroxymethyltransferase Nham_1814 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 92118500 Common - hypothetical protein Nham_3023 9 None None None 92119068 Common - AsmA Nham_3609 62 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 92118773 Nonpathogen - hypothetical protein Nham_3309 2 None None None 92117118 Common secY preprotein translocase subunit SecY Nham_1565 240 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 92116308 Common fliG flagellar motor switch protein G Nham_0690 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 92119285 Nonpathogen - hypothetical protein Nham_3851 2 None None None 92118578 Common - aldehyde dehydrogenase Nham_3110 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 92116407 Common - hypothetical protein Nham_0798 6 None None None 92119287 Common - PRC-barrel Nham_3853 27 COG1873 COG1873, Uncharacterized conserved protein Function unknown 92117057 Common - 3-oxoacyl-(acyl carrier protein) synthase II Nham_1504 180 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92115926 Common - HNH endonuclease Nham_0299 9 None None None 92117213 Nonpathogen - hypothetical protein Nham_1665 3 None None None 92117414 Common - hypothetical protein Nham_1869 27 COG3391 COG3391, Uncharacterized conserved protein Function unknown 92117686 Common - transposase, IS4 Nham_2160 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115932 Common - hypothetical protein Nham_0305 12 None None None 92117314 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Nham_1769 191 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 92117056 Common - 3-oxoacyl-(acyl carrier protein) synthase II Nham_1503 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92118997 Common - Inositol-1(or 4)-monophosphatase Nham_3537 210 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 92116048 Common - ABC transporter related Nham_0426 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 92118930 Nonpathogen - hypothetical protein Nham_3470 2 None None None 92117050 Common - K+ potassium transporter Nham_1497 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 92118180 Common - protein of unknown function DUF892 Nham_2670 37 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 92119000 Nonpathogen - hypothetical protein Nham_3540 1 None None None 92115897 Common - H+-transporting two-sector ATPase, B/B' subunit Nham_0266 28 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 92117332 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Nham_1787 137 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 92118819 Common - hypothetical protein Nham_3357 9 None None None 92117564 Nonpathogen - hypothetical protein Nham_2035 1 None None None 92118311 Common - ABC transporter related Nham_2809 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92119301 Nonpathogen - hypothetical protein Nham_3870 3 None None None 92116197 Nonpathogen - hypothetical protein Nham_0576 1 None None None 92116573 Common - secretion protein HlyD Nham_0992 138 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92118677 Common glyQ glycyl-tRNA synthetase subunit alpha Nham_3211 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 92119425 Common - hypothetical protein Nham_4025 10 None None None 92116216 Common - hypothetical protein Nham_0596 15 None None None 92118981 Common ruvB Holliday junction DNA helicase B Nham_3521 234 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 92116938 Nonpathogen fliL flagellar basal body-associated protein FliL Nham_1385 10 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 92117321 Nonpathogen - hypothetical protein Nham_1776 5 None None None 92118608 Common - MATE efflux family protein Nham_3141 158 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 92117857 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Nham_2334 208 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 92117371 Common - Type I secretion outer membrane protein, TolC Nham_1826 137 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92116256 Common - Phosphate transport system permease protein 2 Nham_0637 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 92118600 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Nham_3133 77 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 92119174 Nonpathogen - hypothetical protein Nham_3717 3 None None None 92117828 Common - Endoribonuclease L-PSP Nham_2305 36 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 92118164 Nonpathogen - hypothetical protein Nham_2653 1 None None None 92119159 Common - GTPase EngB Nham_3702 177 COG0218 COG0218, Predicted GTPase General function prediction only 92116996 Common - cytochrome c, class I Nham_1443 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 92118694 Common - protein of unknown function DUF1159 Nham_3228 29 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 92119280 Common - hypothetical protein Nham_3846 15 COG3831 COG3831, Uncharacterized conserved protein Function unknown 92117949 Common - glutathione S-transferase-like Nham_2428 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92116555 Common - TonB-dependent siderophore receptor Nham_0972 90 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92119268 Nonpathogen - hypothetical protein Nham_3834 1 None None None 92117303 Common - arginyl-tRNA synthetase Nham_1758 246 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92116071 Common - hypothetical protein Nham_0450 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 92119204 Common - AAA ATPase, central region Nham_3749 53 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 92116912 Common - hypothetical protein Nham_1357 7 None None None 92118391 Common - thiamine biosynthesis protein ThiS Nham_2892 33 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 92116922 Nonpathogen - hypothetical protein Nham_1367 1 None None None 92117805 Common pyrB aspartate carbamoyltransferase catalytic subunit Nham_2282 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 92116612 Nonpathogen - hypothetical protein Nham_1033 1 None None None 92117507 Nonpathogen - hypothetical protein Nham_1976 1 None None None 92119250 Nonpathogen - hypothetical protein Nham_3809 1 None None None 92116793 Common - aquaporin Z Nham_1234 123 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 92115719 Common - acyl-CoA thioesterase II Nham_0087 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 92116675 Common - transcriptional regulator, XRE family Nham_1096 52 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 92116143 Common - Iojap-related protein Nham_0522 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 92116740 Common - Integrase, catalytic region Nham_1167 144 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118191 Common - hypothetical protein Nham_2681 17 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 92115956 Nonpathogen - hypothetical protein Nham_0329 2 None None None 92119416 Common - hypothetical protein Nham_4016 16 COG5451 COG5451, Predicted secreted protein Function unknown 92118640 Common xseA exodeoxyribonuclease VII large subunit Nham_3174 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 92119399 Common - transposase IS116/IS110/IS902 Nham_3996 67 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118666 Nonpathogen - hypothetical protein Nham_3200 1 None None None 92117953 Common - 2,5-didehydrogluconate reductase Nham_2432 193 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 92117129 Common - hypothetical protein Nham_1577 8 None None None 92118446 Common - Type I secretion membrane fusion protein, HlyD Nham_2949 109 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92115689 Common - hypothetical protein Nham_0057 61 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 92118398 Nonpathogen - protein of unknown function DUF395, YeeE/YedE Nham_2899 2 COG2391 COG2391, Predicted transporter component General function prediction only 92117890 Common - hypothetical protein Nham_2367 9 None None None 92115691 Common - thioredoxin Nham_0059 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 92116065 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Nham_0444 41 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 92117934 Common - phage integrase Nham_2413 7 None None None 92116610 Common - PDZ/DHR/GLGF Nham_1031 200 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92117023 Common - 3-hydroxyisobutyrate dehydrogenase Nham_1470 186 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 92117351 Common - hypothetical protein Nham_1806 18 None None None 92118126 Common - ABC transporter related Nham_2613 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92117380 Common - Dihydrouridine synthase TIM-barrel protein nifR3 Nham_1835 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 92118658 Common - ErfK/YbiS/YcfS/YnhG Nham_3192 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92116896 Common - Outer membrane autotransporter barrel Nham_1341 44 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92118176 Common dnaE2 error-prone DNA polymerase Nham_2666 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 92118246 Common - hypothetical protein Nham_2736 16 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 92118406 Common - Lytic murein transglycosylase Nham_2907 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 92116682 Common - protein of unknown function DUF992 Nham_1104 12 None None None 92115975 Common - protein of unknown function DUF107 Nham_0348 70 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 92119406 Nonpathogen - hypothetical protein Nham_4006 2 None None None 92116131 Common - Transglycosylase-associated protein Nham_0510 47 COG2261 COG2261, Predicted membrane protein Function unknown 92117845 Common - diguanylate cyclase (GGDEF domain) Nham_2322 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 92118338 Common - hypothetical protein Nham_2837 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118628 Common ileS isoleucyl-tRNA synthetase Nham_3162 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92119042 Common rplS 50S ribosomal protein L19 Nham_3582 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 92118692 Common - glutathione S-transferase-like Nham_3226 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92116087 Common - Hydroxyacylglutathione hydrolase Nham_0466 186 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 92117651 Nonpathogen - hypothetical protein Nham_2123 3 None None None 92117499 Nonpathogen - hypothetical protein Nham_1966 4 None None None 92117692 Nonpathogen - hypothetical protein Nham_2166 4 None None None 92117928 Nonpathogen - hypothetical protein Nham_2406 1 None None None 92117309 Common - DNA gyrase subunit A Nham_1764 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 92115884 Common - peptidase U62, modulator of DNA gyrase Nham_0253 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 92116874 Common - hypothetical protein Nham_1318 89 COG5280 COG5280, Phage-related minor tail protein Function unknown 92118660 Nonpathogen - hypothetical protein Nham_3194 5 None None None 92117254 Common - lipid-A-disaccharide synthase Nham_1707 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 92119435 Nonpathogen - hypothetical protein Nham_4038 3 None None None 92116111 Common - Shikimate kinase Nham_0490 194 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 92118746 Common - multicopper oxidase, type 3 Nham_3281 99 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 92118255 Nonpathogen - hypothetical protein Nham_2745 1 None None None 92118587 Nonpathogen - hypothetical protein Nham_3120 8 None None None 92115953 Common - hypothetical protein Nham_0326 5 None None None 92115696 Common - N-(5'-phosphoribosyl)anthranilate isomerase Nham_0064 195 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 92119320 Nonpathogen - hypothetical protein Nham_3897 1 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 92118095 Nonpathogen - hypothetical protein Nham_2582 7 None None None 92117193 Common rpsD 30S ribosomal protein S4 Nham_1644 245 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 92117514 Nonpathogen - hypothetical protein Nham_1983 2 None None None 92116474 Nonpathogen - hypothetical protein Nham_0878 7 None None None 92117422 Nonpathogen - transcriptional regulator, LuxR family Nham_1881 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 92118005 Common - Uncharacterized phage protein Nham_2484 5 None None None 92118766 Common - sulfatase Nham_3301 19 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 92117465 Common - UspA Nham_1926 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92117607 Common - single-strand DNA-binding protein Nham_2079 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 92118727 Common - transposase Nham_3262 60 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118078 Common - glutathione-dependent formaldehyde-activating, GFA Nham_2565 52 COG3791 COG3791, Uncharacterized conserved protein Function unknown 92115751 Common - Smr protein/MutS2 Nham_0119 67 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 92118966 Common - ATP-dependent metalloprotease FtsH Nham_3506 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 92119135 Common - cytochrome c, class I Nham_3676 10 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 92116966 Common - peptidase U35, phage prohead HK97 Nham_1413 40 COG3740 COG3740, Phage head maturation protease General function prediction only 92118713 Common - Polynucleotide adenylyltransferase region Nham_3247 175 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 92116378 Common - hypothetical protein Nham_0766 14 None None None 92117448 Common - transport-associated Nham_1909 29 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 92118087 Nonpathogen - hypothetical protein Nham_2574 1 COG4371 COG4371, Predicted membrane protein Function unknown 92118774 Common - phage integrase Nham_3311 14 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92117516 Common - type III restriction enzyme, res subunit Nham_1985 41 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 92117287 Nonpathogen - hypothetical protein Nham_1741 1 None None None 92117921 Common - hypothetical protein Nham_2399 37 None None None 92117144 Nonpathogen - hypothetical protein Nham_1592 1 None None None 92117524 Nonpathogen - ATP-dependent endonuclease of the OLD family-like Nham_1994 5 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 92117148 Nonpathogen - hypothetical protein Nham_1596 1 None None None 92118620 Nonpathogen - hypothetical protein Nham_3153 6 None None None 92116461 Common - phosphate acetyltransferase Nham_0864 137 COG0280 Pta, Phosphotransacetylase Energy production and conversion 92117344 Common secD preprotein translocase subunit SecD Nham_1799 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 92117434 Common - acetate kinase Nham_1895 161 COG0282 ackA, Acetate kinase Energy production and conversion 92116121 Common - hypothetical protein Nham_0500 18 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 92118504 Common - hypothetical protein Nham_3027 152 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 92116207 Common - hypothetical protein Nham_0587 41 None None None 92117975 Common rpsI 30S ribosomal protein S9 Nham_2454 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 92116525 Common - Phenylacetic acid degradation protein PaaD Nham_0937 62 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 92118701 Common - hypothetical protein Nham_3235 9 None None None 92117286 Common - major facilitator superfamily MFS_1 Nham_1740 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92117470 Nonpathogen - hypothetical protein Nham_1934 5 None None None 92118024 Nonpathogen - hypothetical protein Nham_2509 3 None None None 92119164 Common - ATPase Nham_3707 101 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 92115725 Common - cyclic nucleotide-binding domain (cNMP-BD) protein Nham_0093 69 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92119193 Nonpathogen - hypothetical protein Nham_3738 1 None None None 92118009 Nonpathogen - hypothetical protein Nham_2488 4 None None None 92116754 Common - ISSpo6, transposase OrfB Nham_1188 39 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116751 Common - cytochrome c, class I Nham_1183 54 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 92118388 Nonpathogen - hypothetical protein Nham_2889 2 None None None 92118440 Common - two component transcriptional regulator, LuxR family Nham_2943 153 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 92118257 Common - peptidase M24 Nham_2747 232 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 92119329 Common - hypothetical protein Nham_3908 8 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 92116652 Nonpathogen - hypothetical protein Nham_1073 1 None None None 92116281 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Nham_0662 237 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 92116081 Common - PfkB Nham_0460 118 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 92116914 Common - metallophosphoesterase Nham_1359 33 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 92117172 Common - hypothetical protein Nham_1622 56 None None None 92117028 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Nham_1475 127 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 92116889 Common - Pyridoxal-dependent decarboxylase Nham_1334 112 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 92118427 Nonpathogen - hypothetical protein Nham_2929 3 None None None 92119111 Common - hypothetical protein Nham_3652 23 None None None 92116768 Common - binding-protein-dependent transport systems inner membrane component Nham_1208 156 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 92118215 Common - Citrate lyase Nham_2705 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 92117568 Common - Cupin 2, conserved barrel Nham_2039 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 92117705 Nonpathogen - hypothetical protein Nham_2181 2 None None None 92119054 Common - 3-isopropylmalate dehydrogenase Nham_3595 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 92117905 Common - GPW/gp25 Nham_2383 27 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 92118785 Common - Phage tail tape measure protein TP901, core region Nham_3322 32 COG5283 COG5283, Phage-related tail protein Function unknown 92118863 Common - LemA Nham_3402 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 92116032 Common - heme exporter protein CcmB Nham_0410 67 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 92116846 Common - DNA ligase, NAD-dependent Nham_1290 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 92116176 Common - dihydroorotate dehydrogenase 2 Nham_0555 229 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 92118830 Common - Flagellar export FliJ Nham_3369 16 None None None 92118976 Common - hypothetical protein Nham_3516 18 None None None 92118346 Common - cold-shock DNA-binding domain protein Nham_2846 175 COG1278 CspC, Cold shock proteins Transcription 92118354 Common - ribonuclease H Nham_2855 172 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 92119136 Common - protein of unknown function DUF938 Nham_3677 49 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 92115837 Common - putative transposase Nham_0206 28 None None None 92118462 Common - ferric uptake regulator, FUR family Nham_2968 192 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 92116831 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Nham_1275 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 92116918 Nonpathogen - hypothetical protein Nham_1363 3 COG3587 COG3587, Restriction endonuclease Defense mechanisms 92116046 Common - Creatininase Nham_0424 87 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 92119333 Common - IstB-like ATP-binding protein Nham_3913 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92116299 Common - ATPase AAA-2 Nham_0681 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 92118048 Common - cyclic nucleotide-binding domain (cNMP-BD) protein Nham_2535 114 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92116810 Nonpathogen - hypothetical protein Nham_1252 2 None None None 92117796 Common - Patatin Nham_2273 15 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 92115873 Common - transcriptional regulator, LysR family Nham_0242 161 COG0583 LysR, Transcriptional regulator Transcription 92118331 Nonpathogen - hypothetical protein Nham_2829 1 None None None 92119100 Common - TonB-like Nham_3641 22 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 92117911 Common - peptidase S14, ClpP Nham_2389 44 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 92119392 Nonpathogen - hypothetical protein Nham_3989 1 None None None 92117483 Common - UspA Nham_1948 44 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92115749 Common - import inner membrane translocase, subunit Tim44 Nham_0117 46 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 92119126 Common - beta-lactamase-like Nham_3667 207 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 92119181 Common - transcriptional regulator, MerR family Nham_3726 145 COG0789 SoxR, Predicted transcriptional regulators Transcription 92116257 Common - Phosphate transport system permease protein 1 Nham_0638 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 92118541 Common - histone-like nucleoid-structuring protein H-NS Nham_3068 20 COG2916 Hns, DNA-binding protein H-NS General function prediction only 92115903 Nonpathogen - hypothetical protein Nham_0272 5 None None None 92119218 Common - hypothetical protein Nham_3764 9 None None None 92116797 Nonpathogen - protein of unknown function DUF465 Nham_1238 6 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 92118837 Common - CheA signal transduction histidine kinase Nham_3376 215 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 92116429 Nonpathogen - hypothetical protein Nham_0822 7 None None None 92116557 Common - hypothetical protein Nham_0974 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 92117457 Common - CBS domain containing membrane protein Nham_1918 97 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 92116288 Common - protein of unknown function DUF218 Nham_0669 31 COG1434 COG1434, Uncharacterized conserved protein Function unknown 92116634 Common - glycosyl transferase, family 2 Nham_1055 153 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92115801 Common - dihydroxy-acid dehydratase Nham_0169 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 92119220 Common - hypothetical protein Nham_3766 57 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 92118977 Common - transcriptional regulator, TetR family Nham_3517 72 COG1309 AcrR, Transcriptional regulator Transcription 92116290 Common - ChaC-like protein Nham_0671 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 92118362 Nonpathogen - hypothetical protein Nham_2863 4 None None None 92118383 Nonpathogen - hypothetical protein Nham_2884 1 None None None 92115772 Nonpathogen - hypothetical protein Nham_0140 1 None None None 92117004 Nonpathogen - hypothetical protein Nham_1451 2 COG5652 COG5652, Predicted integral membrane protein Function unknown 92116230 Common - inorganic pyrophosphatase Nham_0610 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 92118735 Common - 6-phosphogluconate dehydrogenase-like protein Nham_3270 171 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 92116317 Common - hypothetical protein Nham_0699 64 COG3176 COG3176, Putative hemolysin General function prediction only 92118262 Common - S-adenosyl-L-homocysteine hydrolase Nham_2752 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 92115808 Common - ABC transporter related Nham_0176 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 92116237 Common - transcriptional regulator, MarR family Nham_0617 49 COG1846 MarR, Transcriptional regulators Transcription 92118956 Nonpathogen - hypothetical protein Nham_3496 2 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 92116267 Common - NnrS Nham_0648 57 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 92116901 Common - transcriptional regulators, TraR/DksA family Nham_1346 159 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 92117837 Common - N-acetyl-gamma-glutamyl-phosphate reductase Nham_2314 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 92116604 Common - TonB-dependent receptor Nham_1025 109 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 92118018 Common - ISGsu3, transposase Nham_2499 31 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117400 Common - hypothetical protein Nham_1855 16 None None None 92119374 Common - Peptidase M20D, amidohydrolase Nham_3968 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 92116341 Common - hemolysin activation/secretion protein-like Nham_0727 49 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 92116563 Common - Drug resistance transporter EmrB/QacA subfamily Nham_0982 72 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92116642 Common - glycosyl transferase, family 2 Nham_1063 77 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 92115844 Common - RNA polymerase sigma factor Nham_0213 174 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92116105 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Nham_0484 167 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 92118718 Common - protein of unknown function DUF58 Nham_3252 66 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 92115767 Nonpathogen - hypothetical protein Nham_0135 1 None None None 92118328 Common - Twin-arginine translocation pathway signal Nham_2826 5 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 92117376 Common - lipoyl synthase Nham_1831 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 92116240 Common - Na+/H+ antiporter Nham_0621 152 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 92117620 Nonpathogen - hypothetical protein Nham_2092 1 None None None 92116500 Common - 6-phosphofructokinase Nham_0911 152 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 92116905 Common - protein of unknown function DUF955 Nham_1350 47 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 92118611 Common - molybdopterin converting factor, subunit 1 Nham_3144 63 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 92118282 Common - transposase IS116/IS110/IS902 Nham_2773 60 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118801 Common - hypothetical protein Nham_3338 8 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 92117657 Nonpathogen - hypothetical protein Nham_2129 1 None None None 92116547 Common - ABC transporter related Nham_0964 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 92118618 Common - hypothetical protein Nham_3151 10 None None None 92118430 Common - response regulator receiver (CheY-like) modulated diguanylate phosphodiesterase (EAL domain) Nham_2933 159 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 92118159 Common - high-affinity nickel-transporter Nham_2647 32 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 92116073 Common - Lysine exporter protein (LYSE/YGGA) Nham_0452 86 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 92116629 Common - hypothetical protein Nham_1050 8 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 92116249 Common - polysaccharide deacetylase Nham_0630 50 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 92117731 Common - NADH dehydrogenase subunit M Nham_2208 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 92118230 Common - ketol-acid reductoisomerase Nham_2720 213 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 92115736 Common - methyltransferase GidB Nham_0104 192 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 92118534 Common - polysaccharide export protein Nham_3057 74 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 92117786 Common - Lytic transglycosylase, catalytic Nham_2263 145 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 92115796 Common - cytidylate kinase Nham_0164 202 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 92116463 Common - enoyl-(acyl carrier protein) reductase Nham_0866 217 COG0623 FabI, Enoyl- acyl-carrier-protein 92117744 Common - NADH dehydrogenase subunit A Nham_2221 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 92119274 Nonpathogen - hypothetical protein Nham_3840 1 None None None 92116782 Common - Peptidoglycan-binding domain 1 Nham_1223 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 92117229 Nonpathogen - hypothetical protein Nham_1681 1 None None None 92118749 Common - multicopper oxidase, type 3 Nham_3284 132 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 92117279 Common - Indole-3-glycerol-phosphate synthase Nham_1733 217 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 92118152 Common - arginine/ornithine transport system ATPase Nham_2640 101 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 92117085 Common - DNA-directed RNA polymerase subunit beta' Nham_1532 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 92115740 Common rho transcription termination factor Rho Nham_0108 206 COG1158 Rho, Transcription termination factor Transcription 92119360 Nonpathogen - hypothetical protein Nham_3950 1 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 92115757 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Nham_0125 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 92116439 Common - phage tail sheath protein Nham_0832 39 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 92118926 Nonpathogen - hypothetical protein Nham_3466 1 None None None 92117159 Nonpathogen - hypothetical protein Nham_1609 4 None None None 92118225 Common - 2-isopropylmalate synthase Nham_2715 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 92118961 Nonpathogen - hypothetical protein Nham_3501 5 None None None 92116007 Common - Tetratricopeptide TPR_2 Nham_0385 44 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 92116954 Common - hypothetical protein Nham_1401 13 COG5436 COG5436, Predicted integral membrane protein Function unknown 92116183 Common hemC porphobilinogen deaminase Nham_0562 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 92117094 Common - 30S ribosomal protein S7 Nham_1541 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 92117734 Common - NADH dehydrogenase subunit J Nham_2211 145 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 92119249 Common - transposase IS66 Nham_3808 60 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116539 Common - ABC transporter related Nham_0955 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 92116016 Nonpathogen - Flp/Fap pilin component Nham_0394 6 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 92116886 Common - flagellar basal body FlaE Nham_1331 127 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 92116959 Common - Flp/Fap pilin component Nham_1406 15 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 92118549 Nonpathogen - hypothetical protein Nham_3078 2 None None None 92115835 Nonpathogen - hypothetical protein Nham_0204 2 None None None 92118947 Common - HhH-GPD Nham_3487 98 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 92116367 Common - beta-lactamase-like Nham_0754 162 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 92118525 Common - ABC transporter related Nham_3048 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 92118107 Common groEL chaperonin GroEL Nham_2594 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 92119422 Common - hypothetical protein Nham_4022 16 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 92119201 Common - protein of unknown function DUF1013 Nham_3746 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 92116127 Common - 4Fe-4S ferredoxin, iron-sulfur binding Nham_0506 163 COG1146 COG1146, Ferredoxin Energy production and conversion 92118783 Common - phage tail X Nham_3320 3 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 92119266 Common - hypothetical protein Nham_3831 6 None None None 92117802 Common - Holliday junction resolvase YqgF Nham_2279 171 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 92117689 Common lipB lipoyltransferase Nham_2163 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 92117858 Common - peptidase M23B Nham_2335 195 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 92118163 Nonpathogen - hypothetical protein Nham_2652 1 None None None 92117330 Nonpathogen - hypothetical protein Nham_1785 2 None None None 92118633 Common - hypothetical protein Nham_3167 114 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 92118851 Common - hypothetical protein Nham_3390 42 COG3768 COG3768, Predicted membrane protein Function unknown 92117521 Nonpathogen - hypothetical protein Nham_1991 5 None None None 92116199 Common - plasmid maintenance system antidote protein, XRE family Nham_0578 61 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 92117943 Nonpathogen - hypothetical protein Nham_2422 8 None None None 92117323 Nonpathogen - hypothetical protein Nham_1778 1 None None None 92117996 Nonpathogen - hypothetical protein Nham_2475 1 None None None 92116162 Common - dihydrolipoamide acetyltransferase Nham_0541 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 92116775 Nonpathogen - hypothetical protein Nham_1216 3 None None None 92115681 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Nham_0049 205 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92118665 Nonpathogen - hypothetical protein Nham_3199 17 None None None 92118828 Common flhA flagellar biosynthesis protein A Nham_3367 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 92117419 Common - sulphate transporter Nham_1878 119 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 92115915 Common hisD histidinol dehydrogenase Nham_0286 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 92116746 Common groEL chaperonin GroEL Nham_1176 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 92117261 Nonpathogen - hypothetical protein Nham_1714 1 None None None 92118814 Common - putative phage repressor Nham_3352 14 COG2932 COG2932, Predicted transcriptional regulator Transcription 92117611 Nonpathogen - hypothetical protein Nham_2083 1 None None None 92116670 Common - hypothetical protein Nham_1091 34 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 92117631 Nonpathogen - hypothetical protein Nham_2103 4 None None None 92116995 Common - two component transcriptional regulator, winged helix family Nham_1442 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92116191 Nonpathogen - hypothetical protein Nham_0570 1 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 92117774 Common - Ribonuclease III Nham_2251 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 92119063 Common - secretion protein HlyD Nham_3604 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92116587 Common - putative monovalent cation/H+ antiporter subunit E Nham_1007 71 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 92117713 Common - multi-sensor signal transduction histidine kinase Nham_2190 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 92116790 Nonpathogen - hypothetical protein Nham_1231 1 None None None 92117509 Nonpathogen - hypothetical protein Nham_1978 1 None None None 92119350 Nonpathogen - Peptidoglycan-binding domain 1 Nham_3935 4 None None None 92119339 Nonpathogen - small heat shock protein Nham_3919 2 None None None 92118949 Nonpathogen - hypothetical protein Nham_3489 1 None None None 92117615 Common - hypothetical protein Nham_2087 7 None None None 92116972 Common - Phage major tail protein, TP901-1 Nham_1419 19 COG5437 COG5437, Predicted secreted protein Function unknown 92117557 Nonpathogen - hypothetical protein Nham_2028 1 None None None 92119027 Common - protein of unknown function DUF883, ElaB Nham_3567 5 COG4575 ElaB, Uncharacterized conserved protein Function unknown 92116218 Common - phage Gp37Gp68 Nham_0598 42 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 92118494 Nonpathogen - hypothetical protein Nham_3013 2 None None None 92118924 Common - protein of unknown function UPF0066 Nham_3464 99 COG1720 COG1720, Uncharacterized conserved protein Function unknown 92116036 Nonpathogen - hypothetical protein Nham_0414 3 None None None 92119146 Common - Polyhydroxyalkanoate synthesis repressor PhaR Nham_3687 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 92118912 Common - Cytochrome-c oxidase Nham_3452 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 92117119 Common adk adenylate kinase Nham_1566 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 92115931 Nonpathogen - hypothetical protein Nham_0304 1 None None None 92118874 Common - KpsF/GutQ family protein Nham_3413 164 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 92119418 Common - dihydroorotase Nham_4018 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 92115998 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Nham_0376 140 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 92117069 Common - Biopolymer transport protein ExbD/TolR Nham_1516 109 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 92116925 Common - hypothetical protein Nham_1370 12 None None None 92117064 Common - transcriptional regulator, MarR family Nham_1511 131 COG1846 MarR, Transcriptional regulators Transcription 92118113 Nonpathogen - hypothetical protein Nham_2600 3 None None None 92118478 Common - two component transcriptional regulator, winged helix family Nham_2990 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92116660 Common - secretion protein HlyD Nham_1081 121 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92115700 Common - CysZ-like protein Nham_0068 26 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 92115730 Common leuS leucyl-tRNA synthetase Nham_0098 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92118194 Common - Squalene/phytoene synthase Nham_2684 100 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 92117897 Nonpathogen - hypothetical protein Nham_2375 1 None None None 92117187 Common - BolA-like protein Nham_1637 85 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 92118046 Common - cold-shock DNA-binding domain protein Nham_2533 175 COG1278 CspC, Cold shock proteins Transcription 92115924 Nonpathogen - hypothetical protein Nham_0297 4 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 92119281 Common - Resolvase-like Nham_3847 128 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92118185 Common - putative transmembrane transcriptional regulator (anti-sigma factor) Nham_2675 16 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 92119386 Common - hypothetical protein Nham_3982 18 None None None 92116147 Common - protein of unknown function DUF610, YibQ Nham_0526 53 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 92116304 Common - exodeoxyribonuclease V Nham_0686 101 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 92116450 Nonpathogen - hypothetical protein Nham_0850 1 None None None 92116812 Nonpathogen - hypothetical protein Nham_1254 1 None None None 92116990 Common - cytochrome c-type biogenesis protein CycH / CcmH Nham_1437 38 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 92117623 Common - hypothetical protein Nham_2095 6 None None None 92116255 Common - Phosphate ABC transporter, permease protein PstC Nham_0636 226 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 92119291 Nonpathogen - hypothetical protein Nham_3857 1 None None None 92118898 Common - ISSpo6, transposase OrfB Nham_3437 39 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117051 Common - transposase, IS4 Nham_1498 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118894 Common - hypothetical protein Nham_3433 16 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 92115779 Common - Protein of unknown function UPF0011 Nham_0147 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 92115963 Nonpathogen - hypothetical protein Nham_0336 5 None None None 92117750 Common - ATP-dependent protease La Nham_2227 228 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 92117058 Common - Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ Nham_1505 184 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 92116371 Common - acyl-CoA synthetase Nham_0759 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92117879 Common rpsR 30S ribosomal protein S18 Nham_2356 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 92119075 Common - succinate dehydrogenase, cytochrome b subunit Nham_3616 86 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 92116595 Common - hypothetical protein Nham_1016 5 None None None 92116935 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Nham_1382 25 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 92118310 Common - ABC transporter related Nham_2808 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92118360 Common - diguanylate cyclase (GGDEF domain) Nham_2861 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 92118565 Nonpathogen - hypothetical protein Nham_3097 1 None None None 92116405 Common - Resolvase-like Nham_0796 142 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92116488 Nonpathogen - hypothetical protein Nham_0895 1 None None None 92117387 Common - GTP-binding protein, HSR1-related Nham_1842 221 COG2262 HflX, GTPases General function prediction only 92117643 Common - polyphosphate kinase Nham_2115 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 92118755 Common - transposase, IS4 Nham_3290 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115991 Common - 5,10-methylenetetrahydrofolate reductase Nham_0364 150 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 92118919 Common - cytochrome C oxidase assembly protein Nham_3459 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 92115634 Common dnaA chromosomal replication initiation protein Nham_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 92116516 Common - Phenylacetate-CoA oxygenase, PaaG subunit Nham_0928 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 92118995 Common - thiamine monophosphate synthase Nham_3535 33 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 92117100 Common rplW 50S ribosomal protein L23 Nham_1547 230 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 92117919 Nonpathogen - hypothetical protein Nham_2397 1 None None None 92118573 Common - hypothetical protein Nham_3105 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 92118517 Common - Acetyltransferase (isoleucine patch superfamily)-like Nham_3040 6 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 92118884 Common - Homospermidine synthase Nham_3423 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 92118149 Common - glutathione-dependent formaldehyde-activating, GFA Nham_2637 68 COG3791 COG3791, Uncharacterized conserved protein Function unknown 92118301 Common - NAD-dependent epimerase/dehydratase Nham_2798 11 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92117249 Common - surface antigen (D15) Nham_1702 159 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 92117865 Common - Organic solvent tolerance protein Nham_2342 112 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 92117366 Common - transposase, IS4 Nham_1821 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117374 Common - major facilitator superfamily MFS_1 Nham_1829 11 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 92119153 Common - 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase Nham_3696 18 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 92115786 Nonpathogen - hypothetical protein Nham_0154 6 None None None 92116667 Common - thioesterase superfamily Nham_1088 134 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 92118867 Common - Acyl-CoA dehydrogenase Nham_3406 54 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92119304 Nonpathogen - hypothetical protein Nham_3875 1 None None None 92117033 Common - ribose-5-phosphate isomerase A Nham_1480 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 92116356 Common - type II and III secretion system protein Nham_0742 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 92117542 Common - rare lipoprotein A Nham_2012 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 92118393 Common - Thiamine-phosphate diphosphorylase Nham_2894 196 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 92117076 Nonpathogen - hypothetical protein Nham_1523 7 None None None 92117759 Common - Antibiotic biosynthesis monooxygenase Nham_2236 32 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 92117599 Common - extracellular solute-binding protein, family 3 Nham_2071 121 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 92116076 Common - ATP-dependent helicase HrpB Nham_0455 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 92116507 Common - NnrS Nham_0918 50 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 92117923 Nonpathogen - hypothetical protein Nham_2401 1 None None None 92119346 Nonpathogen - hypothetical protein Nham_3930 1 None None None 92118278 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Nham_2769 163 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 92117452 Common - UspA Nham_1913 33 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92116472 Nonpathogen - hypothetical protein Nham_0876 3 None None None 92117526 Nonpathogen - hypothetical protein Nham_1996 7 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 92118202 Common - putative ferredoxin Nham_2692 12 COG1141 Fer, Ferredoxin Energy production and conversion 92115860 Common - polyhydroxyalkanoate depolymerase, intracellular Nham_0229 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 92115716 Common - ammonium transporter Nham_0084 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 92116575 Common - hypothetical protein Nham_0994 5 None None None 92119231 Nonpathogen - hypothetical protein Nham_3780 2 None None None 92118871 Common - hypothetical protein Nham_3410 19 None None None 92118105 Common - hypothetical protein Nham_2592 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 92118213 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Nham_2703 183 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 92119084 Common - hypothetical protein Nham_3625 4 None None None 92116301 Common - Sulfite reductase (NADPH) hemoprotein, beta subunit Nham_0683 151 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 92118687 Common - Ribonuclease H Nham_3221 205 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 92118480 Common - potassium-transporting ATPase, C subunit Nham_2992 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 92118725 Common - Rubrerythrin Nham_3260 24 COG1633 COG1633, Uncharacterized conserved protein Function unknown 92118630 Nonpathogen - hypothetical protein Nham_3164 6 None None None 92115709 Common infC translation initiation factor IF-3 Nham_0077 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 92118732 Common - Glutathione peroxidase Nham_3267 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 92116520 Common - ferredoxin Nham_0932 141 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 92116009 Common - type II secretion system protein Nham_0387 78 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 92118861 Common - protein of unknown function DUF477 Nham_3400 49 COG3762 COG3762, Predicted membrane protein Function unknown 92118800 Common - phage terminase GpA Nham_3337 42 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 92116025 Common - intracellular septation protein A Nham_0403 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 92117339 Common - protein-L-isoaspartate O-methyltransferase Nham_1794 160 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 92118652 Common - protein of unknown function DUF558 Nham_3186 140 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 92119238 Common - hypothetical protein Nham_3789 3 None None None 92118795 Common - GPW/gp25 Nham_3332 28 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 92117459 Nonpathogen - hypothetical protein Nham_1920 9 None None None 92115895 Common - GCN5-related N-acetyltransferase Nham_0264 132 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 92115662 Common nusA transcription elongation factor NusA Nham_0029 218 COG0195 NusA, Transcription elongation factor Transcription 92115961 Common - phage terminase, small subunit, putative, P27 Nham_0334 14 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 92115672 Common - enoyl-(acyl carrier protein) reductase Nham_0040 212 COG0623 FabI, Enoyl- acyl-carrier-protein 92115968 Nonpathogen - hypothetical protein Nham_0341 1 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 92116096 Common - hypothetical protein Nham_0475 23 None None None 92118944 Common - ribonuclease BN Nham_3484 93 COG1295 Rbn, Predicted membrane protein Function unknown 92119044 Common - isopropylmalate isomerase large subunit Nham_3584 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 92116872 Common - ABC transporter related Nham_1316 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 92118266 Nonpathogen - hypothetical protein Nham_2757 2 None None None 92117295 Common - Pyruvate dehydrogenase (lipoamide) Nham_1749 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 92115941 Nonpathogen - hypothetical protein Nham_0314 1 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 92116459 Common - protein of unknown function UPF0118 Nham_0862 102 COG0628 PerM, Predicted permease General function prediction only 92117207 Common - hypothetical protein Nham_1659 14 None None None 92115683 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Nham_0051 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 92117767 Common - arsenate reductase Nham_2244 105 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 92117201 Common - transposase, IS4 Nham_1653 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118298 Common - transposase IS66 Nham_2793 60 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119206 Common rbcL ribulose bisophosphate carboxylase Nham_3751 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 92118567 Common - MaoC-like dehydratase Nham_3099 47 COG2030 MaoC, Acyl dehydratase Lipid metabolism 92117832 Common - homoserine dehydrogenase Nham_2309 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 92119086 Common - hypothetical protein Nham_3627 33 None None None 92116899 Common flgI flagellar basal body P-ring protein Nham_1344 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 92119038 Common - signal recognition particle protein Nham_3578 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 92119149 Common - major facilitator superfamily MFS_1 Nham_3691 109 None None None 92117348 Common - serine/threonine protein kinase Nham_1803 8 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 92118510 Common - Methyltransferase type 11 Nham_3033 3 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 92116145 Common - peptidase M23B Nham_0524 152 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 92116494 Common - protein of unknown function DUF214 Nham_0904 168 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 92117825 Common - elongation factor P Nham_2302 214 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 92119276 Common - protein of unknown function DUF891 Nham_3842 26 COG4679 COG4679, Phage-related protein Function unknown 92117951 Common - hypothetical protein Nham_2430 12 None None None 92116716 Common - heat shock protein Hsp20 Nham_1139 66 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 92118596 Common - SirA-like Nham_3129 65 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 92116988 Common - LipA a lipoprotein Nham_1435 22 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 92118769 Nonpathogen - hypothetical protein Nham_3305 1 None None None 92116823 Common - transposase, IS4 Nham_1266 41 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115646 Common - ISGsu3, transposase Nham_0013 31 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118901 Common - transposase, IS4 Nham_3440 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116703 Nonpathogen - hypothetical protein Nham_1125 2 None None None 92115758 Common - imidazole glycerol phosphate synthase subunit HisF Nham_0126 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 92117139 Common - integration host factor, alpha subunit Nham_1587 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 92117041 Common cysS cysteinyl-tRNA synthetase Nham_1488 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92118531 Common - dTDP-glucose 4,6-dehydratase Nham_3054 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 92115653 Common - ferric uptake regulator, FUR family Nham_0020 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 92116677 Nonpathogen - hypothetical protein Nham_1098 3 None None None 92116695 Common - hypothetical protein Nham_1117 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92116627 Common - Cobyrinic acid a,c-diamide synthase Nham_1048 153 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 92117563 Common - cold-shock DNA-binding domain protein Nham_2034 175 COG1278 CspC, Cold shock proteins Transcription 92116726 Common - DEAD/DEAH box helicase-like Nham_1150 74 COG1204 COG1204, Superfamily II helicase General function prediction only 92116446 Common - phospholipase D/Transphosphatidylase Nham_0845 146 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 92116542 Common - luciferase-like Nham_0958 119 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 92115679 Nonpathogen - Peptidoglycan-binding domain 1 Nham_0047 9 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92117588 Nonpathogen - hypothetical protein Nham_2059 2 None None None 92118951 Common - PDZ/DHR/GLGF Nham_3491 192 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92115987 Common - glycerol kinase Nham_0360 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 92116326 Common - hypothetical protein Nham_0710 6 None None None 92116763 Nonpathogen - hypothetical protein Nham_1200 6 None None None 92115727 Common - hypothetical protein Nham_0095 45 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 92117070 Common - TonB-like Nham_1517 31 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 92118433 Common hemE uroporphyrinogen decarboxylase Nham_2936 177 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 92116441 Common - transposase IS3/IS911 Nham_0835 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117468 Common - hypothetical protein Nham_1930 24 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 92116800 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Nham_1241 188 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 92115775 Common - Recombinase Nham_0143 57 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92118987 Common - hypothetical protein Nham_3527 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 92118536 Common - transposase IS116/IS110/IS902 Nham_3060 73 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117179 Nonpathogen - hypothetical protein Nham_1629 1 None None None 92117368 Common - N-acetylmuramoyl-L-alanine amidase Nham_1823 176 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 92119252 Nonpathogen - hypothetical protein Nham_3811 4 None None None 92117168 Common - glycine dehydrogenase Nham_1618 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 92118591 Common - cytoplasmic chaperone TorD Nham_3124 32 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 92115851 Common - lipolytic enzyme, G-D-S-L Nham_0220 31 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 92119313 Common - transposase and inactivated derivatives-like Nham_3887 63 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116659 Common - methyl-accepting chemotaxis sensory transducer Nham_1080 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 92116689 Common - ferrous iron transport protein B Nham_1111 161 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 92117164 Common - hypothetical protein Nham_1614 10 None None None 92115739 Common - protein of unknown function DUF255 Nham_0107 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 92117485 Common fixK transcriptional regulator FixK Nham_1951 151 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92117416 Nonpathogen - hypothetical protein Nham_1872 1 None None None 92118468 Common - secretion protein HlyD Nham_2977 136 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92117684 Nonpathogen - hypothetical protein Nham_2158 1 None None None 92117463 Nonpathogen - hypothetical protein Nham_1924 5 None None None 92117312 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Nham_1767 193 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 92116982 Common - putative glycohydrolase Nham_1429 26 COG3179 COG3179, Predicted chitinase General function prediction only 92116644 Nonpathogen - hypothetical protein Nham_1065 1 None None None 92118772 Common - PRC-barrel Nham_3308 16 COG1873 COG1873, Uncharacterized conserved protein Function unknown 92119259 Nonpathogen - hypothetical protein Nham_3823 2 None None None 92117102 Common rpsS 30S ribosomal protein S19 Nham_1549 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 92119133 Common - sulfur oxidation protein Nham_3674 35 None None None 92116964 Nonpathogen - hypothetical protein Nham_1411 2 None None None 92117472 Nonpathogen - hypothetical protein Nham_1936 1 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 92116252 Common - hypothetical protein Nham_0633 57 COG0392 COG0392, Predicted integral membrane protein Function unknown 92115821 Common - hypothetical protein Nham_0189 29 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 92117638 Common - malic enzyme Nham_2110 213 COG0281 SfcA, Malic enzyme Energy production and conversion 92117741 Common - NADH dehydrogenase subunit D Nham_2218 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 92119089 Common - 4Fe-4S ferredoxin, iron-sulfur binding Nham_3630 157 COG1146 COG1146, Ferredoxin Energy production and conversion 92116279 Common - peptidase M23B Nham_0660 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 92118344 Nonpathogen - hypothetical protein Nham_2844 1 None None None 92118259 Common - protein of unknown function DUF899, thioredoxin-like Nham_2749 26 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 92118304 Common - glycosyl transferase, family 4 Nham_2802 69 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 92117181 Common - cyanate hydratase Nham_1631 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 92118506 Common - hypothetical protein Nham_3029 16 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92116714 Common gltD glutamate synthase subunit beta Nham_1137 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 92116083 Common - DNA polymerase III subunits gamma and tau Nham_0462 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 92118000 Nonpathogen - Phage protein, HK97, gp10 Nham_2479 3 None None None 92117650 Common - Nucleoside-diphosphate kinase Nham_2122 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 92117031 Nonpathogen - hypothetical protein Nham_1478 3 None None None 92118425 Nonpathogen - hypothetical protein Nham_2927 4 None None None 92116619 Common - molybdopterin dehydrogenase, FAD-binding Nham_1040 96 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 92116364 Common - sodium/hydrogen exchanger Nham_0751 202 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 92117518 Common - NUDIX hydrolase Nham_1987 22 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 92119247 Common - transposase IS3/IS911 Nham_3806 17 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117227 Common - small multidrug resistance protein Nham_1679 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 92117544 Nonpathogen - hypothetical protein Nham_2015 1 None None None 92119279 Common - DNA modification methyltransferase-related protein Nham_3845 52 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 92118474 Common - protein of unknown function DUF323 Nham_2985 93 COG1262 COG1262, Uncharacterized conserved protein Function unknown 92119331 Nonpathogen - hypothetical protein Nham_3911 1 None None None 92118080 Common - import inner membrane translocase, subunit Tim44 Nham_2567 22 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 92119011 Common - hypothetical protein Nham_3551 58 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 92115864 Common - beta-lactamase-like Nham_0233 216 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 92116640 Common - dTDP-4-dehydrorhamnose reductase Nham_1061 166 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 92118499 Common - UDP-glucose 4-epimerase Nham_3022 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 92119382 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Nham_3977 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 92117967 Common - hypothetical protein Nham_2446 19 None None None 92118439 Nonpathogen - hypothetical protein Nham_2942 2 None None None 92119113 Common - transposase, IS4 Nham_3654 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119056 Common - superoxide dismutase, copper/zinc binding Nham_3597 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 92117170 Common - glycine cleavage system T protein Nham_1620 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 92119224 Common - hypothetical protein Nham_3770 16 COG2135 COG2135, Uncharacterized conserved protein Function unknown 92117799 Nonpathogen - hypothetical protein Nham_2276 3 None None None 92118128 Common - Extracellular ligand-binding receptor Nham_2615 147 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 92117142 Common - hypothetical protein Nham_1590 2 None None None 92118464 Common - ABC transporter related Nham_2970 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 92117027 Common - Twin-arginine translocation pathway signal Nham_1474 85 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 92118193 Common - amine oxidase Nham_2683 41 COG3349 COG3349, Uncharacterized conserved protein Function unknown 92117432 Nonpathogen - hypothetical protein Nham_1893 1 None None None 92118223 Nonpathogen - hypothetical protein Nham_2713 1 None None None 92117703 Nonpathogen - hypothetical protein Nham_2179 3 None None None 92116030 Common - aconitate hydratase Nham_0408 223 COG1048 AcnA, Aconitase A Energy production and conversion 92119359 Nonpathogen - hypothetical protein Nham_3949 1 None None None 92118913 Common - cytochrome o ubiquinol oxidase subunit III Nham_3453 157 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 92116174 Common - ATP-dependent DNA ligase Nham_0553 98 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 92117146 Common - transposase Nham_1594 60 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117346 Common - protein of unknown function DUF498 Nham_1801 38 COG3737 COG3737, Uncharacterized conserved protein Function unknown 92116276 Nonpathogen - hypothetical protein Nham_0657 5 None None None 92115639 Nonpathogen - hypothetical protein Nham_0006 1 None None None 92115794 Common - endonuclease III Nham_0162 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 92116559 Common - putative serine protein kinase, PrkA Nham_0976 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 92117021 Common - hypothetical protein Nham_1468 28 COG3577 COG3577, Predicted aspartyl protease General function prediction only 92116680 Common - glutathione S-transferase-like Nham_1101 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92119322 Nonpathogen - hypothetical protein Nham_3899 1 None None None 92116537 Common - nitrate reductase, alpha subunit Nham_0951 102 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 92117080 Common rplK 50S ribosomal protein L11 Nham_1527 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 92118669 Common - FAD linked oxidase-like Nham_3203 152 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 92117862 Common - leucyl aminopeptidase Nham_2339 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 92118691 Common - DNA methylase N-4/N-6 Nham_3225 136 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 92116944 Common - hypothetical protein Nham_1391 13 COG5373 COG5373, Predicted membrane protein Function unknown 92117584 Common - DEAD/DEAH box helicase-like Nham_2055 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 92115694 Common trpA tryptophan synthase subunit alpha Nham_0062 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 92118626 Common - response regulator receiver domain protein (CheY-like) Nham_3160 210 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 92116089 Common - hypothetical protein Nham_0468 31 None None None 92117353 Common - acetyltransferase Nham_1808 45 COG2388 COG2388, Predicted acetyltransferase General function prediction only 92118174 Common - threonine dehydratase Nham_2664 206 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 92118698 Common - protein of unknown function DUF454 Nham_3232 86 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 92117388 Nonpathogen - hypothetical protein Nham_1843 1 None None None 92117728 Common - beta-lactamase-like Nham_2205 152 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 92118007 Common - HNH endonuclease Nham_2486 5 None None None 92118404 Nonpathogen - hypothetical protein Nham_2905 3 COG4371 COG4371, Predicted membrane protein Function unknown 92118964 Common - cell wall hydrolase, SleB Nham_3504 44 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 92119051 Common - Carbonate dehydratase Nham_3592 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 92116122 Common - Patatin Nham_0501 120 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 92117574 Common - Integral membrane protein TerC Nham_2045 94 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 92118656 Common - YdjC-like protein Nham_3190 51 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 92116444 Nonpathogen - hypothetical protein Nham_0841 4 None None None 92118839 Common - 3'(2'),5'-bisphosphate nucleotidase Nham_3378 168 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 92118674 Nonpathogen - hypothetical protein Nham_3208 3 None None None 92116118 Common - hypothetical protein Nham_0497 144 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 92117986 Common - glycosyl transferase, group 1 Nham_2465 201 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92115722 Common - cell divisionFtsK/SpoIIIE Nham_0090 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 92117673 Nonpathogen - hypothetical protein Nham_2146 1 None None None 92118025 Nonpathogen - hypothetical protein Nham_2510 3 None None None 92119160 Common - putative inner membrane protein translocase component YidC Nham_3703 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 92118554 Common - transposase IS116/IS110/IS902 Nham_3085 81 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117699 Nonpathogen - hypothetical protein Nham_2175 1 COG4907 COG4907, Predicted membrane protein Function unknown 92119428 Common - peptidase M, neutral zinc metallopeptidases, zinc-binding site Nham_4029 49 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 92116868 Common - glycosyl transferase, group 1 Nham_1312 170 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92118150 Common - methylmalonyl-CoA mutase Nham_2638 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 92116133 Common - transposase, IS4 Nham_0512 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119433 Nonpathogen - hypothetical protein Nham_4036 3 None None None 92118616 Common - protein of unknown function DUF519 Nham_3149 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 92119283 Common - hypothetical protein Nham_3849 2 None None None 92116933 Common - transposase, mutator type Nham_1379 83 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117661 Nonpathogen - hypothetical protein Nham_2133 1 None None None 92117629 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Nham_2101 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 92117609 Common uvrA excinuclease ABC subunit A Nham_2081 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 92119408 Common - phage-related integrase Nham_4008 9 None None None 92119046 Nonpathogen - hypothetical protein Nham_3587 1 None None None 92116108 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Nham_0487 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 92118679 Common - peptidase S49 Nham_3213 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 92117420 Common - peptidase S1 and S6, chymotrypsin/Hap Nham_1879 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92118649 Common - hypothetical protein Nham_3183 9 None None None 92117252 Common - UDP-N-acetylglucosamine acyltransferase Nham_1705 147 COG1043 LpxA, Acyl- acyl carrier protein 92115830 Common - protein of unknown function DUF1674 Nham_0198 7 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 92117467 Common - protein-L-isoaspartate O-methyltransferase Nham_1929 166 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 92119245 Common - signal transduction histidine kinase Nham_3802 38 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92118134 Common - TonB-dependent receptor, plug Nham_2621 121 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 92117655 Common - Carbamoyltransferase Nham_2127 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 92119257 Nonpathogen - hypothetical protein Nham_3819 1 None None None 92116833 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Nham_1277 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 92118093 Nonpathogen - hypothetical protein Nham_2580 8 None None None 92116949 Common fliR flagellar biosynthesis protein FliR Nham_1396 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 92117120 Common rpsM 30S ribosomal protein S13 Nham_1567 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 92118858 Common - hypothetical protein Nham_3397 3 None None None 92118011 Common - peptidase U35, phage prohead HK97 Nham_2490 40 COG3740 COG3740, Phage head maturation protease General function prediction only 92117687 Common - phosphoesterase, PA-phosphatase related Nham_2161 11 None None None 92118244 Common - hypothetical protein Nham_2734 32 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 92117595 Common - cysteine synthase A Nham_2067 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 92116952 Nonpathogen - hypothetical protein Nham_1399 4 None None None 92115734 Common - parB-like partition proteins Nham_0102 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 92118711 Common - Tetratricopeptide TPR_2 Nham_3245 45 None None None 92115866 Common - PAS/PAC sensor hybrid histidine kinase Nham_0235 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92117362 Common - riboflavin synthase subunit alpha Nham_1817 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 92116292 Common - cyclohexadienyl dehydrogenase Nham_0673 174 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 92119195 Nonpathogen - hypothetical protein Nham_3740 1 None None None 92118848 Common - Isovaleryl-CoA dehydrogenase Nham_3387 171 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92119166 Common - hypothetical protein Nham_3709 8 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 92116784 Common - Peptidase M3B, oligoendopeptidase-related clade 3 Nham_1225 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 92118284 Common - glycosyl transferase, group 1 Nham_2776 153 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92117736 Common - NADH dehydrogenase subunit H Nham_2213 188 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 92118703 Common - adenine phosphoribosyltransferase Nham_3237 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 92116848 Common - ABC transporter related Nham_1292 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 92116437 Nonpathogen - hypothetical protein Nham_0830 7 None None None 92115742 Common - transposase, mutator type Nham_0110 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117881 Nonpathogen - hypothetical protein Nham_2358 1 None None None 92118527 Common - Methyltransferase type 11 Nham_3050 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92115833 Common - extracellular solute-binding protein, family 3 Nham_0202 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 92115857 Common - PII uridylyl-transferase Nham_0226 126 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 92116134 Common - hypothetical protein Nham_0513 9 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 92118832 Common - two component transcriptional regulator, winged helix family Nham_3371 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92115822 Common - Uncharacterized protein involved in methicillin resistance-like Nham_0190 21 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 92116287 Common - protein of unknown function DUF214 Nham_0668 77 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 92118081 Common - protein of unknown function DUF1491 Nham_2568 22 COG5447 COG5447, Uncharacterized conserved protein Function unknown 92118367 Common - N-formylglutamate amidohydrolase Nham_2868 39 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 92117096 Common - elongation factor Tu Nham_1543 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 92116010 Common - type II secretion system protein E Nham_0388 159 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 92117390 Common mazG nucleoside triphosphate pyrophosphohydrolase Nham_1845 157 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 92117711 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Nham_2188 186 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 92119272 Common - cell divisionFtsK/SpoIIIE Nham_3838 174 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 92117087 Common - ABC transporter related Nham_1534 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 92118356 Common - phage integrase Nham_2857 17 None None None 92118743 Common - Drug resistance transporter EmrB/QacA subfamily Nham_3278 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92116502 Common - Ferritin and Dps Nham_0913 132 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 92117199 Common - Patatin Nham_1650 121 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 92116907 Common - helicase-like Nham_1352 157 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 92117221 Common - ABC transporter related Nham_1673 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92115839 Nonpathogen - hypothetical protein Nham_0208 1 None None None 92117610 Nonpathogen - hypothetical protein Nham_2082 4 COG4371 COG4371, Predicted membrane protein Function unknown 92115893 Common - threonine synthase Nham_0262 175 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 92116799 Common - FAD dependent oxidoreductase Nham_1240 95 COG0579 COG0579, Predicted dehydrogenase General function prediction only 92115905 Common - periplasmic sensor hybrid histidine kinase Nham_0274 218 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 92116152 Common - F0F1 ATP synthase subunit gamma Nham_0531 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 92116903 Nonpathogen - hypothetical protein Nham_1348 3 None None None 92118543 Nonpathogen - hypothetical protein Nham_3072 2 None None None 92116063 Common - periplasmic sensor signal transduction histidine kinase Nham_0442 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92117800 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Nham_2277 150 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 92115977 Common - inner-membrane translocator Nham_0350 139 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 92116854 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Nham_1298 220 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92117402 Nonpathogen - hypothetical protein Nham_1857 2 None None None 92119216 Nonpathogen - hypothetical protein Nham_3762 3 None None None 92116221 Common - beta-lactamase/D-alanine carboxypeptidase Nham_0601 120 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 92118385 Nonpathogen - hypothetical protein Nham_2886 6 None None None 92116000 Common - extracellular solute-binding protein, family 5 Nham_0378 166 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 92116381 Common - Phosphoglycerate mutase Nham_0769 169 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 92117870 Nonpathogen - hypothetical protein Nham_2347 3 None None None 92117913 Common - phage portal protein, lambda Nham_2391 19 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 92119369 Common - membrane protein-like Nham_3961 15 COG4420 COG4420, Predicted membrane protein Function unknown 92116898 Common - chemotactic signal-response protein CheL Nham_1343 12 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 92115770 Nonpathogen - hypothetical protein Nham_0138 1 None None None 92117405 Nonpathogen - hypothetical protein Nham_1860 1 None None None 92118035 Nonpathogen - hypothetical protein Nham_2522 1 None None None 92117961 Common - NUDIX hydrolase Nham_2440 27 None None None 92118720 Common - hypothetical protein Nham_3254 34 COG5426 COG5426, Uncharacterized membrane protein Function unknown 92117835 Common - Poly(R)-hydroxyalkanoic acid synthase, class I Nham_2312 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 92115938 Nonpathogen - hypothetical protein Nham_0311 1 None None None 92116319 Nonpathogen - hypothetical protein Nham_0702 3 None None None 92118092 Common - serine O-acetyltransferase Nham_2579 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 92119124 Common - 3-demethylubiquinone-9 3-methyltransferase Nham_3665 60 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 92119222 Common - UvrD/REP helicase Nham_3768 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 92116265 Common - response regulator receiver domain protein (CheY-like) Nham_0646 48 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92116414 Common - transposase Nham_0807 60 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117410 Nonpathogen - hypothetical protein Nham_1865 2 None None None 92116422 Nonpathogen - hypothetical protein Nham_0815 4 None None None 92116841 Common - cell division protein FtsA Nham_1285 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 92118938 Common - thioredoxin-like protein Nham_3478 141 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 92119373 Common - putative transposase of insertion sequence ISRm2011-2, orfA protein Nham_3967 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116349 Common - putative general secretory pathway protein K Nham_0735 14 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 92116242 Common - Polyprenyl synthetase Nham_0623 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 92116527 Nonpathogen - hypothetical protein Nham_0939 1 None None None 92118206 Common - protein of unknown function DUF395, YeeE/YedE Nham_2696 23 None None None 92116235 Common - Drug resistance transporter EmrB/QacA subfamily Nham_0615 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92117830 Common - single-stranded-DNA-specific exonuclease RecJ Nham_2307 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 92117854 Common anmK anhydro-N-acetylmuramic acid kinase Nham_2331 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 92115842 Nonpathogen - hypothetical protein Nham_0211 1 None None None 92118570 Common - peptidyl-tRNA hydrolase Nham_3102 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 92118264 Nonpathogen - hypothetical protein Nham_2754 3 None None None 92118983 Common ruvC Holliday junction resolvase Nham_3523 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 92116180 Common - protein of unknown function DUF589 Nham_0559 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 92116262 Common - ornithine carbamoyltransferase Nham_0643 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 92117853 Common - hypothetical protein Nham_2330 84 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 92116496 Common - secretion protein HlyD Nham_0906 162 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92119073 Common - glycoside hydrolase 15-related Nham_3614 72 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 92119293 Common - putative integrase Nham_3859 24 None None None 92119191 Common - glucan exporter ATP-binding protein Nham_3736 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 92116306 Common - flagellar motor switch protein Nham_0688 126 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 92116374 Common - Mg2+ transporter protein, CorA-like Nham_0762 159 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 92119429 Nonpathogen - hypothetical protein Nham_4030 1 None None None 92118575 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Nham_3107 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 92118336 Common - tISRso5; ISRSO5-transposase protein Nham_2834 47 None None None 92115936 Nonpathogen - hypothetical protein Nham_0309 1 None None None 92118014 Nonpathogen - hypothetical protein Nham_2493 1 None None None 92119069 Common - acriflavin resistance protein Nham_3610 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92118896 Common - protein of unknown function DUF156 Nham_3435 100 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 92116075 Common - acyltransferase 3 Nham_0454 25 COG4763 COG4763, Predicted membrane protein Function unknown 92118211 Common - transcriptional regulator, TetR family Nham_2701 68 COG1309 AcrR, Transcriptional regulator Transcription 92117481 Nonpathogen - hypothetical protein Nham_1945 7 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 92115688 Common - Nucleotidyl transferase Nham_0056 221 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 92118757 Common - TonB-dependent siderophore receptor Nham_3292 103 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92117752 Common - Endopeptidase Clp Nham_2229 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 92117534 Common - protein of unknown function UPF0060 Nham_2004 50 COG1742 COG1742, Uncharacterized conserved protein Function unknown 92118379 Common - thioredoxin reductase Nham_2880 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 92118716 Common - protein of unknown function DUF1285 Nham_3250 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 92118758 Common - two component transcriptional regulator, winged helix family Nham_3293 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92118316 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase Nham_2814 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 92116150 Common - F0F1 ATP synthase subunit beta Nham_0529 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 92118770 Nonpathogen - hypothetical protein Nham_3306 1 None None None 92118074 Common - nuclear protein SET Nham_2561 24 COG2940 COG2940, Proteins containing SET domain General function prediction only 92117153 Nonpathogen - hypothetical protein Nham_1602 1 None None None 92118563 Common - prolipoprotein diacylglyceryl transferase Nham_3095 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 92116002 Common - binding-protein-dependent transport systems inner membrane component Nham_0380 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 92116593 Common - phage Tail Collar Nham_1014 37 COG4675 MdpB, Microcystin-dependent protein Function unknown 92119123 Common - ribonucleotide-diphosphate reductase subunit beta Nham_3664 151 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 92116522 Common - bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase Nham_0934 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 92118147 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Nham_2635 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 92116018 Nonpathogen - TadE-like Nham_0396 11 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 92119183 Common - periplasmic binding protein Nham_3728 33 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 92118869 Nonpathogen - hypothetical protein Nham_3408 1 None None None 92115922 Common - hypothetical protein Nham_0295 16 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 92117593 Common - secretion protein HlyD Nham_2065 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92116470 Common - protein of unknown function DUF1275 Nham_0874 12 COG3619 COG3619, Predicted membrane protein Function unknown 92119155 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Nham_3698 138 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 92119004 Common - ABC transporter, ATP-binding/permease protein Nham_3544 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 92119411 Common - protein of unknown function DUF159 Nham_4011 109 COG2135 COG2135, Uncharacterized conserved protein Function unknown 92117958 Common - DNA topoisomerase I Nham_2437 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 92117364 Common nusB transcription antitermination protein NusB Nham_1819 173 COG0781 NusB, Transcription termination factor Transcription 92116055 Common - Molybdate ABC transporter, ATP-binding protein Nham_0433 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 92118777 Nonpathogen - hypothetical protein Nham_3314 1 None None None 92119388 Nonpathogen - hypothetical protein Nham_3985 2 None None None 92118985 Common - hypothetical protein Nham_3525 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 92118603 Common - periplasmic sensor signal transduction histidine kinase Nham_3136 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92116979 Common - gene transfer agent (GTA) orfg15, like protein Nham_1426 27 None None None 92119144 Common - histidine kinase Nham_3685 209 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92117776 Common acpS 4'-phosphopantetheinyl transferase Nham_2253 138 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 92116509 Common - maleylacetoacetate isomerase Nham_0920 60 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92118470 Common - protein of unknown function DUF1214 Nham_2979 39 COG5361 COG5361, Uncharacterized conserved protein Function unknown 92116200 Common - putative plasmid maintenance system antidote protein, XRE family Nham_0579 77 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 92117788 Common - putative porin Nham_2265 15 None None None 92117074 Common - hypothetical protein Nham_1521 16 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 92117245 Common - undecaprenyl diphosphate synthase Nham_1698 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 92119203 Common - AMP-dependent synthetase and ligase Nham_3748 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 92117617 Common - hypothetical protein Nham_2089 8 None None None 92118229 Common - Substrate-binding region of ABC-type glycine betaine transport system Nham_2719 140 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 92118160 Common - protein of unknown function DUF156 Nham_2648 89 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 92118291 Common - transposase, mutator type Nham_2785 74 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116020 Common - cold-shock DNA-binding domain protein Nham_0398 177 COG1278 CspC, Cold shock proteins Transcription 92117633 Common - CreA Nham_2105 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 92117649 Common - hypothetical protein Nham_2121 43 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 92116777 Common - pyruvate kinase Nham_1218 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 92118237 Common - HflC protein Nham_2727 214 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 92117998 Common - hypothetical protein Nham_2477 12 None None None 92117110 Common rplE 50S ribosomal protein L5 Nham_1557 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 92119264 Common - hypothetical protein Nham_3829 4 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 92119170 Common - hypothetical protein Nham_3713 6 None None None 92115917 Common - protein tyrosine phosphatase Nham_0288 108 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 92115951 Nonpathogen - hypothetical protein Nham_0324 2 None None None 92115948 Nonpathogen - hypothetical protein Nham_0321 1 None None None 92117307 Common - putative transcriptional regulator Nham_1762 135 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 92117809 Nonpathogen - hypothetical protein Nham_2286 3 COG5373 COG5373, Predicted membrane protein Function unknown 92117125 Common - recombination factor protein RarA Nham_1573 231 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 92116098 Common - protein of unknown function DUF1178 Nham_0477 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 92119236 Nonpathogen - hypothetical protein Nham_3785 2 None None None 92116209 Nonpathogen - hypothetical protein Nham_0589 2 None None None 92116732 Common - ISSpo6, transposase OrfB Nham_1156 39 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115685 Common - PAS/PAC sensor signal transduction histidine kinase Nham_0053 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 92117130 Common - type III secretion protein Nham_1578 119 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 92115965 Common - peptidase U35, phage prohead HK97 Nham_0338 43 COG3740 COG3740, Phage head maturation protease General function prediction only 92116825 Nonpathogen - hypothetical protein Nham_1269 1 None None None 92118889 Common - ABC transporter related Nham_3428 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 92118115 Common - hypothetical protein Nham_2602 112 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 92118816 Nonpathogen - hypothetical protein Nham_3354 1 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 92119208 Common - Phosphoribulokinase Nham_3753 52 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 92118829 Nonpathogen - hypothetical protein Nham_3368 3 None None None 92118136 Common - multi-sensor signal transduction histidine kinase Nham_2623 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92117216 Common - nitroreductase Nham_1668 86 COG0778 NfnB, Nitroreductase Energy production and conversion 92118663 Nonpathogen - hypothetical protein Nham_3197 3 None None None 92117062 Common - acriflavin resistance protein Nham_1509 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92117771 Common recO DNA repair protein RecO Nham_2248 37 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 92119345 Common - putative transposase Nham_3929 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 92117886 Nonpathogen - hypothetical protein Nham_2363 2 None None None 92116354 Common - type II secretion system protein Nham_0740 141 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 92118519 Common - UDP-glucose/GDP-mannose dehydrogenase Nham_3042 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 92116672 Common - Twin-arginine translocation pathway signal Nham_1093 83 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 92118450 Nonpathogen - aspartate/glutamate/uridylate kinase Nham_2954 15 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 92118737 Common - 6-phosphogluconolactonase Nham_3272 118 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 92117559 Nonpathogen - hypothetical protein Nham_2030 1 None None None 92116927 Nonpathogen - hypothetical protein Nham_1372 1 None None None 92119380 Common - Uncharacterized membrane-associated protein-like Nham_3975 164 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 92115780 Common - Extracellular ligand-binding receptor Nham_0148 27 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 92119395 Nonpathogen - hypothetical protein Nham_3992 1 None None None 92116756 Common - polysaccharide biosynthesis protein CapD Nham_1193 164 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92118931 Nonpathogen - hypothetical protein Nham_3471 3 None None None 92116997 Common - major facilitator superfamily MFS_1 Nham_1444 101 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 92117895 Common - phage tail X Nham_2372 4 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 92115848 Common - crcB protein Nham_0217 179 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 92118760 Common - periplasmic sensor signal transduction histidine kinase Nham_3295 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92119061 Common - acriflavin resistance protein Nham_3602 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92117945 Common - transposase, IS4 Nham_2424 18 None None None 92116865 Common - putative transcriptional regulator, AsnC family Nham_1309 19 COG1522 Lrp, Transcriptional regulators Transcription 92118372 Nonpathogen - Methyltransferase type 12 Nham_2873 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92117378 Common - CinA-like Nham_1833 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 92118140 Nonpathogen - hypothetical protein Nham_2628 5 None None None 92119009 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Nham_3549 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 92116394 Nonpathogen - hypothetical protein Nham_0784 3 None None None 92117275 Common - LexA repressor Nham_1729 168 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 92119233 Common - hypothetical protein Nham_3782 17 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 92117068 Common - MotA/TolQ/ExbB proton channel Nham_1515 126 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 92116977 Common - Phage conserved hypothetical protein BR0599 Nham_1424 31 COG5449 COG5449, Uncharacterized conserved protein Function unknown 92116193 Common - Cobyrinic acid a,c-diamide synthase Nham_0572 192 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 92115980 Nonpathogen - hypothetical protein Nham_0353 3 None None None 92117613 Common - hypothetical protein Nham_2085 6 None None None 92116744 Common - NADH dehydrogenase subunit D Nham_1172 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 92115789 Common - Ribosomal RNA adenine methylase transferase Nham_0157 41 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 92117162 Common - hypothetical protein Nham_1612 10 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 92116679 Common - glucose sorbosone dehydrogenase Nham_1100 126 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 92117185 Common - phosphoribosylformylglycinamidine synthase I Nham_1635 230 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 92118958 Common - hypothetical protein Nham_3498 14 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 92118989 Common - protein of unknown function DUF710 Nham_3529 27 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 92116431 Nonpathogen - hypothetical protein Nham_0824 10 None None None 92118807 Nonpathogen - hypothetical protein Nham_3345 1 None None None 92116366 Common - acyl-CoA dehydrogenase-like Nham_0753 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92117012 Common - protein of unknown function DUF59 Nham_1459 156 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 92116518 Common - Phenylacetate-CoA oxygenase, PaaI subunit Nham_0930 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 92116585 Common - putative monovalent cation/H+ antiporter subunit G Nham_1005 34 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 92116149 Common - ATP synthase F1, epsilon subunit Nham_0528 159 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 92117043 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Nham_1490 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 92118876 Common hemH ferrochelatase Nham_3415 151 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 92116761 Common - Haloacid dehalogenase-like hydrolase Nham_1198 145 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 92116957 Common - hypothetical protein Nham_1404 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 92115993 Common - putative transposase Nham_0366 12 None None None 92117561 Nonpathogen - hypothetical protein Nham_2032 3 None None None 92118459 Common - Nitrite reductase (NAD(P)H) large subunit, NirD Nham_2964 72 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 92119018 Common - Sulfate ABC transporter, permease protein CysW Nham_3558 189 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 92117550 Common - phage terminase, small subunit, putative, P27 Nham_2021 14 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 92117157 Common - Mu-like prophage major head subunit gpT Nham_1607 17 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 92116697 Common - D-3-phosphoglycerate dehydrogenase Nham_1119 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 92117668 Common - protein of unknown function DUF192 Nham_2141 86 COG1430 COG1430, Uncharacterized conserved protein Function unknown 92119319 Nonpathogen - hypothetical protein Nham_3896 1 None None None 92115989 Common - putative PAS/PAC sensor protein Nham_0362 86 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 92117325 Nonpathogen - hypothetical protein Nham_1780 5 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 92116625 Nonpathogen - hypothetical protein Nham_1046 1 None None None 92118055 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Nham_2542 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 92117166 Common recA recombinase A Nham_1616 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 92116479 Common - histidine kinase Nham_0884 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92115811 Common - 3'-5' exonuclease Nham_0179 115 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 92118781 Common - phage late control D Nham_3318 37 COG3500 COG3500, Phage protein D General function prediction only 92118552 Nonpathogen - hypothetical protein Nham_3082 1 None None None 92117209 Nonpathogen - putative CheA signal transduction histidine kinases, no good domain identification Nham_1661 8 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 92117523 Common - Helicase c2 Nham_1993 10 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 92116728 Common - PRC-barrel protein Nham_1152 21 None None None 92116984 Nonpathogen - hypothetical protein Nham_1431 1 None None None 92116549 Nonpathogen - hypothetical protein Nham_0966 1 None None None 92118469 Common - hypothetical protein Nham_2978 10 None None None 92116388 Common - 1-deoxy-D-xylulose-5-phosphate synthase Nham_0778 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 92117177 Common - tISRso5; ISRSO5-transposase protein Nham_1627 47 None None None 92116632 Common - Sel1-like Nham_1053 109 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 92118395 Common - thiamine biosynthesis protein ThiC Nham_2896 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 92118647 Common - inositol monophosphatase Nham_3181 193 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 92119093 Common - hypothetical protein Nham_3634 26 COG3656 COG3656, Predicted periplasmic protein Function unknown 92118218 Common - hypothetical protein Nham_2708 21 None None None 92117746 Common - histone-like DNA-binding protein Nham_2223 198 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 92116817 Nonpathogen - hypothetical protein Nham_1259 3 None None None 92117636 Nonpathogen - hypothetical protein Nham_2108 3 None None None 92118271 Common - hypothetical protein Nham_2762 11 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 92116687 Common - Shikimate 5-dehydrogenase Nham_1109 218 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 92118651 Nonpathogen - hypothetical protein Nham_3185 6 None None None 92118970 Common - hypothetical protein Nham_3510 8 None None None 92119311 Common - putative GAF sensor protein Nham_3882 150 COG0628 PerM, Predicted permease General function prediction only 92116657 Common - Rhodanese-like Nham_1078 110 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 92117816 Common - amidophosphoribosyltransferase Nham_2293 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 92115714 Common - peptidase S16, lon-like Nham_0082 76 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 92117122 Common - DNA-directed RNA polymerase subunit alpha Nham_1569 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 92119243 Common - protein of unknown function DUF892 Nham_3795 24 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 92115761 Common - multi-sensor hybrid histidine kinase Nham_0129 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92116468 Common - two component transcriptional regulator, LuxR family Nham_0872 221 COG4566 TtrR, Response regulator Signal transduction mechanisms 92118204 Common - OsmC-like protein Nham_2694 62 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 92118946 Common - glutamyl-Q tRNA(Asp) synthetase Nham_3486 242 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 92118705 Common - YbhB and YbcL Nham_3239 127 COG1881 COG1881, Phospholipid-binding protein General function prediction only 92116699 Nonpathogen - hypothetical protein Nham_1121 1 None None None 92115862 Common - response regulator receiver domain protein (CheY-like) Nham_0231 209 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 92116577 Common - glutamate dehydrogenase Nham_0996 171 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 92116666 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Nham_1087 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 92117528 Nonpathogen - hypothetical protein Nham_1998 5 None None None 92116513 Common - hypothetical protein Nham_0924 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 92117721 Common - copper resistance D Nham_2198 20 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 92118779 Nonpathogen - hypothetical protein Nham_3316 1 None None None 92117297 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Nham_1751 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 92116164 Common - succinyl-CoA synthetase, alpha subunit Nham_0543 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 92117940 Nonpathogen - hypothetical protein Nham_2419 14 COG5490 COG5490, Uncharacterized conserved protein Function unknown 92117105 Common rplP 50S ribosomal protein L16 Nham_1552 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 92119033 Common - signal transduction histidine kinase Nham_3573 29 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92116457 Common - putative transcriptional regulator, XRE family Nham_0859 152 COG0517 COG0517, FOG: CBS domain General function prediction only 92116391 Common - Enoyl-CoA hydratase/isomerase Nham_0781 167 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 92117827 Common - Lytic murein transglycosylase Nham_2304 106 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 92116078 Common - hypothetical protein Nham_0457 52 COG3577 COG3577, Predicted aspartyl protease General function prediction only 92118797 Common - hypothetical protein Nham_3334 3 None None None 92115664 Common infB translation initiation factor IF-2 Nham_0031 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 92116701 Common - adenylosuccinate synthetase Nham_1123 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 92119219 Common - DNA polymerase III, alpha subunit Nham_3765 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 92118790 Nonpathogen - hypothetical protein Nham_3327 2 None None None 92118020 Nonpathogen - hypothetical protein Nham_2503 1 None None None 92117490 Nonpathogen - hypothetical protein Nham_1957 3 None None None 92116650 Common - formate/nitrite transporter Nham_1071 86 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 92117965 Common - hypothetical protein Nham_2444 22 None None None 92116012 Common - pilus assembly protein CpaD Nham_0390 15 COG5461 COG5461, Type IV pili component Cell motility and secretion 92118419 Common - hypothetical protein Nham_2921 9 None None None 92117204 Common - nitrogen-fixing NifU-like Nham_1656 62 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 92118066 Common - HI0933-like protein Nham_2553 135 COG2081 COG2081, Predicted flavoproteins General function prediction only 92116345 Common - peptidase A24A, prepilin type IV Nham_0731 53 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 92115648 Common - UspA Nham_0015 25 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92117337 Common surE stationary phase survival protein SurE Nham_1792 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 92116599 Common - hypothetical protein Nham_1020 5 None None None 92117190 Common - protein of unknown function DUF323 Nham_1640 89 COG1262 COG1262, Uncharacterized conserved protein Function unknown 92119082 Common - argininosuccinate synthase Nham_3623 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 92117973 Common - protein of unknown function UPF0066 Nham_2452 93 COG1720 COG1720, Uncharacterized conserved protein Function unknown 92119226 Nonpathogen - hypothetical protein Nham_3775 1 None None None 92117341 Common - Chromate transporter Nham_1796 98 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 92116332 Common - transcriptional regulator, TetR family Nham_0716 103 COG1309 AcrR, Transcriptional regulator Transcription 92116835 Common murG N-acetylglucosaminyl transferase Nham_1279 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 92115882 Nonpathogen - hypothetical protein Nham_0251 7 None None None 92119106 Common - inner-membrane translocator Nham_3647 161 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 92116648 Nonpathogen - hypothetical protein Nham_1069 1 None None None 92119367 Common - transposase IS3/IS911 Nham_3959 10 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118483 Common - IS66 Orf2 like Nham_2996 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116664 Common fadE acyl-CoA dehydrogenase Nham_1085 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92116757 Common - DegT/DnrJ/EryC1/StrS aminotransferase Nham_1194 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 92118558 Common - nuclease (SNase-like) Nham_3090 35 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 92116510 Common - homogentisate 1,2-dioxygenase Nham_0921 53 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 92115869 Common - GCN5-related N-acetyltransferase Nham_0238 112 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 92116588 Common - putative monovalent cation/H+ antiporter subunit D Nham_1008 206 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 92116515 Common - fumarylacetoacetase Nham_0926 66 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 92115957 Common - Exonuclease Nham_0330 102 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 92115705 Common pheT phenylalanyl-tRNA synthetase subunit beta Nham_0073 224 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 92118051 Common - ABC transporter related Nham_2538 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 92118098 Nonpathogen - Twin-arginine translocation pathway signal Nham_2585 3 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 92118885 Common - hypothetical protein Nham_3424 48 COG2319 COG2319, FOG: WD40 repeat General function prediction only 92117586 Common - D-fructose-6-phosphate amidotransferase Nham_2057 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 92115788 Common - Chaperone DnaJ Nham_0156 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 92116814 Common - hypothetical protein Nham_1256 31 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 92116435 Nonpathogen - hypothetical protein Nham_0828 12 None None None 92117726 Common - protein of unknown function DUF1467 Nham_2203 21 COG5454 COG5454, Predicted secreted protein Function unknown 92118323 Common - nicotinate-nucleotide pyrophosphorylase Nham_2821 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 92116655 Common - hypothetical protein Nham_1076 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 92117496 Nonpathogen - hypothetical protein Nham_1963 2 None None None 92115896 Common - hypothetical protein Nham_0265 10 None None None 92116978 Common - Putative phage cell wall peptidase, NlpC/P60 Nham_1425 17 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 92117882 Nonpathogen - hypothetical protein Nham_2359 1 None None None 92118741 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Nham_3276 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 92117871 Common gmk guanylate kinase Nham_2348 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 92117790 Common - Tetratricopeptide TPR_2 Nham_2267 15 None None None 92117107 Common rpsQ 30S ribosomal protein S17 Nham_1554 220 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 92118170 Nonpathogen - hypothetical protein Nham_2660 9 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 92115677 Common - Glycolate reductase Nham_0045 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 92119227 Nonpathogen - hypothetical protein Nham_3776 1 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 92115670 Common - catalase/peroxidase HPI Nham_0037 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 92116027 Nonpathogen - hypothetical protein Nham_0405 8 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 92115665 Common rbfA ribosome-binding factor A Nham_0032 130 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 92117663 Common - transposase Nham_2135 60 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117678 Common - hypothetical protein Nham_2151 7 None None None 92118846 Common - ErfK/YbiS/YcfS/YnhG Nham_3385 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92115640 Common - hypothetical protein Nham_0007 20 None None None 92116530 Common - filamentous haemagglutinin-like Nham_0943 121 None None None 92117856 Common - hypothetical protein Nham_2333 33 None None None 92117008 Common - Carbon-monoxide dehydrogenase Nham_1455 85 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 92115720 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase Nham_0088 135 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 92117053 Common - hypothetical protein Nham_1500 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 92116497 Nonpathogen - hypothetical protein Nham_0907 1 None None None 92118209 Common - acriflavin resistance protein Nham_2699 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92116583 Common - protein of unknown function DUF490 Nham_1002 66 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 92119242 Common - PRC-barrel Nham_3794 31 None None None 92116608 Common - CHAD Nham_1029 76 COG3025 COG3025, Uncharacterized conserved protein Function unknown 92115916 Common - hypothetical protein Nham_0287 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 92118574 Common - pyrroline-5-carboxylate reductase Nham_3106 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 92116802 Common - binding-protein-dependent transport systems inner membrane component Nham_1244 191 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 92118130 Common - peptidase S58, DmpA Nham_2617 49 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92115675 Common - ferric uptake regulator, FUR family Nham_0043 120 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 92116347 Nonpathogen - putative general secretion pathway protein M Nham_0733 4 None None None 92117829 Common - transposase IS116/IS110/IS902 Nham_2306 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117941 Common - Serine-type D-Ala-D-Ala carboxypeptidase Nham_2420 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 92117292 Common - Isoprenylcysteine carboxyl methyltransferase Nham_1746 19 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 92117956 Common - polysaccharide deacetylase Nham_2435 92 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 92116712 Nonpathogen - hypothetical protein Nham_1134 1 None None None 92117241 Common rpsB 30S ribosomal protein S2 Nham_1694 217 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 92116671 Common - Lytic murein transglycosylase Nham_1092 98 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 92116707 Common - methionine sulfoxide reductase A Nham_1129 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 92117992 Nonpathogen - hypothetical protein Nham_2471 1 None None None 92118878 Common - Peptidyl-dipeptidase Dcp Nham_3417 124 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 92117719 Common - Lipoprotein releasing system, transmembrane protein, LolC/E family Nham_2196 164 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 92117396 Nonpathogen - hypothetical protein Nham_1851 4 None None None 92118533 Common - Protein-tyrosine kinase Nham_3056 136 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 92118453 Common - putative porin Nham_2957 13 None None None 92116226 Common - short-chain dehydrogenase/reductase SDR Nham_0606 221 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 92117360 Common - hypothetical protein Nham_1815 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 92117329 Common - Nucleotidyl transferase Nham_1784 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 92116721 Nonpathogen - hypothetical protein Nham_1144 1 None None None 92116166 Common - malate dehydrogenase Nham_0545 190 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 92118685 Common - phage SPO1 DNA polymerase-related protein Nham_3219 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 92118824 Nonpathogen - hypothetical protein Nham_3362 1 None None None 92117327 Nonpathogen - hypothetical protein Nham_1782 5 None None None 92118002 Common - phage terminase, small subunit, putative, P27 Nham_2481 14 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 92117220 Common - ABC transporter related Nham_1672 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92116690 Common - L-lactate dehydrogenase (cytochrome) Nham_1112 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 92117175 Nonpathogen - hypothetical protein Nham_1625 1 None None None 92115667 Common rpsO 30S ribosomal protein S15 Nham_0034 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 92117391 Common - ExsB Nham_1846 171 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 92118751 Common - transcriptional regulator, BadM/Rrf2 family Nham_3286 136 COG1959 COG1959, Predicted transcriptional regulator Transcription 92119316 Nonpathogen - hypothetical protein Nham_3893 1 None None None 92118308 Nonpathogen - hypothetical protein Nham_2806 1 None None None 92117765 Common - arginyl-tRNA-protein transferase Nham_2242 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 92115810 Common - hypothetical protein Nham_0178 27 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 92117415 Common - protein of unknown function LppY and LpqO Nham_1870 16 None None None 92116989 Nonpathogen - hypothetical protein Nham_1436 5 None None None 92118429 Nonpathogen - hypothetical protein Nham_2932 1 None None None 92119013 Common - polysaccharide biosynthesis protein Nham_3553 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 92116617 Nonpathogen - hypothetical protein Nham_1038 2 None None None 92116050 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Nham_0428 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 92117132 Common - Alkylhydroperoxidase AhpD core Nham_1580 82 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 92118084 Common - hypothetical protein Nham_2571 12 None None None 92118594 Common - 4Fe-4S ferredoxin, iron-sulfur binding Nham_3127 174 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 92119101 Common - SecA DEAD-like Nham_3642 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 92115881 Common - glutamate--cysteine ligase Nham_0250 55 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 92117233 Nonpathogen - hypothetical protein Nham_1685 3 None None None 92115743 Common - conserved hypothetical protein 701 Nham_0111 96 COG1981 COG1981, Predicted membrane protein Function unknown 92116820 Nonpathogen - hypothetical protein Nham_1262 1 None None None 92115982 Common - ABC transporter related Nham_0355 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92117136 Common - hypothetical protein Nham_1584 29 None None None 92117748 Nonpathogen - hypothetical protein Nham_2225 3 None None None 92115754 Common - Imidazoleglycerol-phosphate dehydratase Nham_0122 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 92117426 Common - two component transcriptional regulator, winged helix family Nham_1885 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92118420 Nonpathogen - hypothetical protein Nham_2922 3 None None None 92118416 Common - Transglycosylase-associated protein Nham_2918 10 None None None 92116809 Nonpathogen - Phasin 2 Nham_1251 9 COG5490 COG5490, Uncharacterized conserved protein Function unknown 92118486 Common - two component transcriptional regulator, LuxR family Nham_3000 153 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 92116442 Nonpathogen - hypothetical protein Nham_0836 4 None None None 92116044 Common - ferredoxin-dependent glutamate synthase Nham_0422 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 92117302 Common - Deoxyguanosinetriphosphate triphosphohydrolase Nham_1757 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 92117757 Common - glutamine synthetase, type I Nham_2234 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 92118447 Common - hypothetical protein Nham_2951 19 None None None 92118763 Common - Heavy metal efflux pump CzcA Nham_3298 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 92118491 Common - transposase IS3/IS911 Nham_3008 28 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117770 Common - DNA topoisomerase IV subunit A Nham_2247 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 92116067 Common - Beta-lactamase Nham_0446 67 COG2367 PenP, Beta-lactamase class A Defense mechanisms 92117152 Nonpathogen - hypothetical protein Nham_1601 1 None None None 92119398 Common - transposase IS116/IS110/IS902 Nham_3995 69 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117156 Nonpathogen - hypothetical protein Nham_1606 4 None None None 92117203 Nonpathogen - hypothetical protein Nham_1655 9 COG3904 COG3904, Predicted periplasmic protein Function unknown 92119156 Common - Pyrimidine 5-nucleotidase Nham_3699 47 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 92116911 Nonpathogen - hypothetical protein Nham_1356 2 None None None 92116921 Nonpathogen - hypothetical protein Nham_1366 4 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116194 Nonpathogen - hypothetical protein Nham_0573 1 None None None 92116661 Common - acriflavin resistance protein Nham_1082 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92119348 Nonpathogen - hypothetical protein Nham_3932 1 None None None 92119205 Common - Ribulose-bisphosphate carboxylase Nham_3750 29 COG4451 RbcS, Ribulose bisphosphate carboxylase small subunit Energy production and conversion 92118293 Nonpathogen - hypothetical protein Nham_2788 2 None None None 92119067 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Nham_3608 48 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 92117779 Common - DNA-directed RNA polymerase subunit omega Nham_2256 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 92118553 Common - transposase IS116/IS110/IS902 Nham_3083 72 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118070 Common - enoyl-CoA hydratase Nham_2557 148 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 92118037 Nonpathogen - hypothetical protein Nham_2524 2 None None None 92118992 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Nham_3532 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 92119302 Common - hypothetical protein Nham_3871 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 92117987 Common - sugar transferase Nham_2466 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 92115929 Nonpathogen - hypothetical protein Nham_0302 1 None None None 92118667 Nonpathogen - hypothetical protein Nham_3201 1 None None None 92118696 Common - Chromosome segregation protein SMC Nham_3230 177 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 92118273 Common - glycosyl transferase, group 1 Nham_2764 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92118568 Nonpathogen - hypothetical protein Nham_3100 4 None None None 92119179 Nonpathogen - hypothetical protein Nham_3723 2 None None None 92116331 Common - General substrate transporter Nham_0715 162 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 92117011 Common - hypothetical protein Nham_1458 10 None None None 92117838 Common - DedA Nham_2315 94 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 92117017 Common - glycogen branching enzyme Nham_1464 146 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 92117572 Nonpathogen - hypothetical protein Nham_2043 1 None None None 92117530 Common - hypothetical protein Nham_2000 14 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 92115935 Common - endodeoxyribonuclease RusA Nham_0308 5 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 92117682 Nonpathogen - putative transcriptional regulator Nham_2156 1 COG3311 AlpA, Predicted transcriptional regulator Transcription 92115898 Common - H+-transporting two-sector ATPase, B/B' subunit Nham_0267 65 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 92117737 Common - NADH dehydrogenase subunit G Nham_2214 193 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 92119426 Common - putative plasmid maintenance system antidote protein, XRE family Nham_4027 79 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 92118980 Common - 4-hydroxybenzoyl-CoA thioesterase Nham_3520 119 COG0824 FcbC, Predicted thioesterase General function prediction only 92118875 Common - transposase, IS4 Nham_3414 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115994 Common - cold-shock DNA-binding domain protein Nham_0367 175 COG1278 CspC, Cold shock proteins Transcription 92118190 Common - Radical SAM Nham_2680 111 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 92115967 Nonpathogen - hypothetical protein Nham_0340 1 None None None 92119269 Common - replication protein Nham_3835 11 COG5655 COG5655, Plasmid rolling circle replication initiator protein and truncated derivatives DNA replication, recombination, and repair 92118312 Common - inner-membrane translocator Nham_2810 86 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 92117804 Common - acyl-CoA dehydrogenase-like Nham_2281 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92117115 Common rpsE 30S ribosomal protein S5 Nham_1562 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 92118607 Common - transposase, IS4 Nham_3140 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118672 Common - transcriptional regulator, TetR family Nham_3206 13 COG1309 AcrR, Transcriptional regulator Transcription 92118738 Common - Carbohydrate kinase, thermoresistant glucokinase Nham_3273 81 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 92118234 Common - phosphoserine phosphatase SerB Nham_2724 148 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 92119008 Common - Alcohol dehydrogenase, zinc-binding Nham_3548 209 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 92117946 Common - Uncharacterised conserved protein UCP032025 Nham_2425 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 92118144 Common - hypothetical protein Nham_2632 12 None None None 92117503 Nonpathogen - hypothetical protein Nham_1972 2 None None None 92116827 Common - methyltransferase Nham_1271 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 92116878 Nonpathogen - hypothetical protein Nham_1323 4 None None None 92116404 Common - hypothetical protein Nham_0795 11 None None None 92117820 Nonpathogen - hypothetical protein Nham_2297 2 COG2339 COG2339, Predicted membrane protein Function unknown 92118635 Common mutL DNA mismatch repair protein Nham_3169 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 92116056 Common modB molybdate ABC transporter permease protein Nham_0434 233 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 92118993 Common pgk phosphoglycerate kinase Nham_3533 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 92117479 Nonpathogen - hypothetical protein Nham_1943 1 None None None 92116129 Common - peptidase M48, Ste24p Nham_0508 126 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 92116359 Common - hypothetical protein Nham_0745 14 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 92115647 Common - transposase, IS4 Nham_0014 19 None None None 92116947 Nonpathogen fliE flagellar hook-basal body protein FliE Nham_1394 9 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 92118503 Common - Type I secretion system ATPase, PrtD Nham_3026 236 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 92117430 Common - Heavy metal efflux pump CzcA Nham_1889 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 92119025 Common - malate synthase G Nham_3565 70 COG2225 AceB, Malate synthase Energy production and conversion 92118376 Nonpathogen - hypothetical protein Nham_2877 1 None None None 92118514 Common - DegT/DnrJ/EryC1/StrS aminotransferase Nham_3037 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 92118577 Common - Pyruvate dehydrogenase (lipoamide) Nham_3109 157 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 92117310 Nonpathogen - hypothetical protein Nham_1765 3 None None None 92118731 Common - hypothetical protein Nham_3266 30 None None None 92118186 Common - aminotransferase class-III Nham_2676 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 92119341 Common - hypothetical protein Nham_3922 9 None None None 92117212 Nonpathogen - hypothetical protein Nham_1664 1 None None None 92117273 Common - phage Terminase Nham_1726 45 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 92115729 Common - glutathione S-transferase-like Nham_0097 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92118397 Nonpathogen - hypothetical protein Nham_2898 6 None None None 92118334 Common - hypothetical protein Nham_2832 7 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 92117893 Common - Methyltransferase FkbM Nham_2370 30 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 92117685 Nonpathogen - hypothetical protein Nham_2159 1 None None None 92116300 Common - sulfite reductase (NADPH) flavoprotein, alpha chain Nham_0682 106 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 92118834 Common - chemotaxis-specific methylesterase Nham_3373 210 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 92117504 Common - hypothetical protein Nham_1973 10 None None None 92118232 Common - acetolactate synthase 3 catalytic subunit Nham_2722 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 92116350 Nonpathogen - putative general secretion pathway protein J Nham_0736 4 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 92117927 Common - putative phage repressor Nham_2405 8 COG2932 COG2932, Predicted transcriptional regulator Transcription 92116398 Common - Integrase, catalytic region Nham_0789 80 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118818 Common - hypothetical protein Nham_3356 4 None None None 92119071 Common - major facilitator superfamily MFS_1 Nham_3612 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92117111 Common rpsN 30S ribosomal protein S14 Nham_1558 189 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 92116142 Common nadD nicotinic acid mononucleotide adenyltransferase Nham_0521 113 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 92119173 Common - TonB-dependent receptor, plug Nham_3716 123 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92116375 Nonpathogen - hypothetical protein Nham_0763 1 None None None 92117565 Nonpathogen - hypothetical protein Nham_2036 1 None None None 92117900 Common - phage tail sheath protein Nham_2378 39 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 92117538 Common - methionyl-tRNA synthetase Nham_2008 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92117546 Nonpathogen - hypothetical protein Nham_2017 1 None None None 92116213 Common - TRAG protein Nham_0593 63 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 92118601 Common - MoeA-like, domain I and II Nham_3134 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 92117037 Nonpathogen - diacylglycerol kinase Nham_1484 4 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 92118860 Nonpathogen - hypothetical protein Nham_3399 5 None None None 92117032 Common - phosphoglycolate phosphatase Nham_1479 188 COG0546 Gph, Predicted phosphatases General function prediction only 92117383 Common - multi-sensor signal transduction histidine kinase Nham_1838 204 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 92115637 Common gyrB DNA gyrase subunit B Nham_0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 92116189 Common - Recombinase Nham_0568 92 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92118063 Common - Ppx/GppA phosphatase Nham_2550 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 92119078 Common sdhB succinate dehydrogenase iron-sulfur subunit Nham_3619 198 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 92116765 Common - IstB-like ATP-binding protein Nham_1203 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92118497 Nonpathogen - hypothetical protein Nham_3016 1 None None None 92118319 Common - Stress responsive alpha-beta barrel Nham_2817 8 None None None 92117555 Common - peptidase U35, phage prohead HK97 Nham_2026 43 COG3740 COG3740, Phage head maturation protease General function prediction only 92116942 Nonpathogen - tetratricopeptide TPR_4 protein Nham_1389 9 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 92118313 Common - Twin-arginine translocation pathway signal Nham_2811 89 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 92116343 Common - Biopolymer transport protein ExbD/TolR Nham_0729 97 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 92117591 Common - acriflavin resistance protein Nham_2063 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92118390 Common - Glycine oxidase ThiO Nham_2891 83 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 92118358 Common - Pseudouridine synthase, RluD Nham_2859 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 92118054 Common - fatty acid desaturase Nham_2541 37 COG3239 DesA, Fatty acid desaturase Lipid metabolism 92118929 Nonpathogen - hypothetical protein Nham_3469 1 None None None 92119267 Nonpathogen - hypothetical protein Nham_3833 1 None None None 92116466 Common fixK transcriptional regulator FixK Nham_0870 138 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92116641 Common - glycosyl transferase, family 2 Nham_1062 89 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 92116590 Common - putative monovalent cation/H+ antiporter subunit A Nham_1010 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 92116480 Common - hypothetical protein Nham_0885 30 COG4371 COG4371, Predicted membrane protein Function unknown 92118959 Nonpathogen - hypothetical protein Nham_3499 1 None None None 92115891 Common - cytochrome c oxidase, subunit III Nham_0260 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 92118249 Common - UvrD/REP helicase Nham_2739 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 92116314 Common - Phosphatidylethanolamine N-methyltransferase Nham_0696 71 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92119168 Common - glycoside hydrolase, family 25 Nham_3711 32 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 92119196 Nonpathogen - hypothetical protein Nham_3741 3 None None None 92116335 Common - ABC-2 Nham_0719 143 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 92116258 Common - phosphate uptake regulator, PhoU Nham_0639 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 92117831 Common glpX fructose 1,6-bisphosphatase II Nham_2308 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 92115806 Nonpathogen - hypothetical protein Nham_0174 1 None None None 92116157 Common xerC site-specific tyrosine recombinase XerC Nham_0536 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92116285 Nonpathogen - Zinc finger/thioredoxin putative Nham_0666 12 None None None 92118380 Common - transcriptional regulator, LysR family Nham_2881 188 COG0583 LysR, Transcriptional regulator Transcription 92115841 Common - electron transport protein SCO1/SenC Nham_0210 106 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 92118412 Common - ErfK/YbiS/YcfS/YnhG Nham_2914 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92119019 Common - Sulfate ABC transporter, permease protein CysT Nham_3559 238 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 92116013 Common - type II and III secretion system protein Nham_0391 139 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 92117277 Nonpathogen - hypothetical protein Nham_1731 8 None None None 92115768 Nonpathogen - hypothetical protein Nham_0136 2 None None None 92117963 Common pleD response regulator PleD Nham_2442 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 92115906 Common - 5-aminolevulinate synthase Nham_0276 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 92119356 Common - transposase Nham_3945 26 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118695 Common - Twin-arginine translocation pathway signal Nham_3229 99 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 92116384 Common - methyl-accepting chemotaxis sensory transducer Nham_0772 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 92119104 Common - Extracellular ligand-binding receptor Nham_3645 127 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 92116880 Nonpathogen - hypothetical protein Nham_1325 3 None None None 92119214 Common - hypothetical protein Nham_3759 5 None None None 92118680 Common - methyltransferase small Nham_3214 53 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 92119383 Nonpathogen - hypothetical protein Nham_3979 1 None None None 92119098 Common - MotA/TolQ/ExbB proton channel Nham_3639 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 92119184 Common - ABC transporter related Nham_3729 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 92117488 Common - hypothetical protein Nham_1955 3 None None None 92118475 Nonpathogen - hypothetical protein Nham_2986 1 None None None 92117932 Nonpathogen - hypothetical protein Nham_2410 1 None None None 92115763 Nonpathogen - hypothetical protein Nham_0131 1 None None None 92117205 Common - GTP cyclohydrolase I Nham_1657 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 92116993 Common - cytochrome C biogenesis protein Nham_1440 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 92116851 Common - HAD-superfamily hydrolase subfamily IIIA Nham_1295 128 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 92118544 Common - hypothetical protein Nham_3073 16 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92116123 Common rpmB 50S ribosomal protein L28 Nham_0502 142 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 92117914 Common - phage terminase GpA Nham_2392 38 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 92119198 Common - ribonuclease H Nham_3743 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 92117358 Nonpathogen - hypothetical protein Nham_1813 1 None None None 92118642 Common - hypothetical protein Nham_3176 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 92118043 Nonpathogen - Prevent-host-death protein Nham_2530 4 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 92119262 Nonpathogen - hypothetical protein Nham_3827 3 None None None 92115865 Nonpathogen - hypothetical protein Nham_0234 8 None None None 92117393 Common - outer membrane efflux protein Nham_1848 104 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92116282 Common - methylated-DNA--protein-cysteine methyltransferase Nham_0663 205 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 92115875 Common - hypothetical protein Nham_0244 28 None None None 92118351 Common - plasmid maintenance system antidote protein, XRE family Nham_2852 80 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 92117642 Common - Ppx/GppA phosphatase Nham_2114 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 92118637 Common - Pseudouridine synthase, Rsu Nham_3171 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 92119161 Nonpathogen - ribonuclease P protein component Nham_3704 11 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 92116410 Common - Phage uncharacterized protein-like Nham_0801 32 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 92116141 Common - gamma-glutamyl phosphate reductase Nham_0520 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 92117196 Nonpathogen - hypothetical protein Nham_1647 1 None None None 92116630 Common - ABC transporter related Nham_1051 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 92117412 Common - major facilitator superfamily MFS_1 Nham_1867 15 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 92116843 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Nham_1287 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 92118102 Common - hypothetical protein Nham_2589 12 None None None 92118242 Common fumC fumarate hydratase Nham_2732 204 COG0114 FumC, Fumarase Energy production and conversion 92117907 Common - hypothetical protein Nham_2385 3 None None None 92117226 Common - phosphate transporter Nham_1678 166 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 92117600 Common - cystathionine beta-lyase Nham_2072 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 92118240 Common thyA thymidylate synthase Nham_2730 143 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 92118287 Common - ABC transporter related Nham_2779 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 92115744 Common - hypothetical protein Nham_0112 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 92116049 Common - binding-protein-dependent transport systems inner membrane component Nham_0427 83 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 92117088 Common - monooxygenase, FAD-binding Nham_1535 9 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 92115753 Common - ATP-dependent protease peptidase subunit Nham_0121 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 92118708 Common - tRNA/rRNA methyltransferase (SpoU) Nham_3242 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 92116091 Common prfA peptide chain release factor 1 Nham_0470 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 92116535 Common - protein of unknown function DUF81 Nham_0948 35 COG0730 COG0730, Predicted permeases General function prediction only 92117218 Nonpathogen - hypothetical protein Nham_1670 4 None None None 92118168 Nonpathogen - hypothetical protein Nham_2658 4 None None None 92117335 Common - Sec-independent protein translocase TatC Nham_1790 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 92119002 Common - hypothetical protein Nham_3542 149 COG1360 MotB, Flagellar motor protein Cell motility and secretion 92115911 Common - Resolvase-like Nham_0282 58 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92117081 Common rplA 50S ribosomal protein L1 Nham_1528 233 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 92116838 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Nham_1282 200 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 92118806 Nonpathogen - NusG antitermination factor Nham_3343 1 COG0250 NusG, Transcription antiterminator Transcription 92116103 Common - NUDIX hydrolase Nham_0482 162 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 92116245 Nonpathogen - hypothetical protein Nham_0626 10 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 92118605 Common - transcriptional regulator, MarR family Nham_3138 46 COG1846 MarR, Transcriptional regulators Transcription 92117257 Common - glutaminyl-tRNA synthetase Nham_1710 234 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 92119256 Common - signal transduction histidine kinase Nham_3818 78 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92116419 Nonpathogen - hypothetical protein Nham_0812 1 None None None 92115901 Common - FoF1 ATP synthase, subunit I Nham_0270 16 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 92117091 Nonpathogen - hypothetical protein Nham_1538 1 None None None 92115776 Common - Mg chelatase-related protein Nham_0144 186 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 92116061 Common - PTS system fructose subfamily IIA component Nham_0440 94 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 92117441 Common - CBS domain containing membrane protein Nham_1902 155 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 92119286 Common - ATP dependent DNA ligase Nham_3852 109 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 92116674 Common - transposase, IS4 Nham_1095 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117669 Common - cold-shock DNA-binding domain protein Nham_2142 153 COG1278 CspC, Cold shock proteins Transcription 92116564 Common - type I phosphodiesterase/nucleotide pyrophosphatase Nham_0983 17 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 92117098 Common rplC 50S ribosomal protein L3 Nham_1545 236 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 92118076 Nonpathogen - hypothetical protein Nham_2563 3 None None None 92117510 Common - AAA ATPase, central region Nham_1979 181 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 92116969 Common - peptidase S1 and S6, chymotrypsin/Hap Nham_1416 12 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 92115888 Common - protoheme IX farnesyltransferase Nham_0257 169 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 92115950 Nonpathogen - hypothetical protein Nham_0323 1 None None None 92117180 Nonpathogen - hypothetical protein Nham_1630 2 None None None 92119364 Common - nuclease (SNase-like) Nham_3956 49 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 92117237 Nonpathogen - hypothetical protein Nham_1689 2 None None None 92117693 Common - Peroxidase Nham_2167 207 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 92116236 Common - secretion protein HlyD Nham_0616 160 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92118022 Common - PRC-barrel Nham_2506 20 None None None 92115976 Common - periplasmic sensor hybrid histidine kinase Nham_0349 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92116113 Common - protein of unknown function DUF21 Nham_0492 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 92116932 Common - transposase IS116/IS110/IS902 Nham_1378 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119381 Common - NADPH-dependent FMN reductase Nham_3976 109 COG0431 COG0431, Predicted flavoprotein General function prediction only 92117868 Common ksgA dimethyladenosine transferase Nham_2345 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 92118325 Common - transcriptional regulator, AraC family Nham_2823 35 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 92119372 Common - hypothetical protein Nham_3965 26 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92119325 Common - hypothetical protein Nham_3903 15 None None None 92118444 Common - hypothetical protein Nham_2947 7 None None None 92116004 Common - ABC transporter related Nham_0382 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 92116114 Nonpathogen - type IV pilus assembly PilZ Nham_0493 3 None None None 92115827 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Nham_0195 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 92117698 Nonpathogen - nodulate formation efficiency C protein Nham_2173 2 None None None 92116211 Nonpathogen - hypothetical protein Nham_0591 1 None None None 92119121 Common - protein of unknown function DUF208 Nham_3662 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 92116251 Nonpathogen - hypothetical protein Nham_0632 3 None None None 92117763 Common - delta-aminolevulinic acid dehydratase Nham_2240 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 92117126 Nonpathogen - hypothetical protein Nham_1574 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 92117795 Common - transposase IS116/IS110/IS902 Nham_2272 54 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117513 Nonpathogen - hypothetical protein Nham_1982 5 None None None 92116967 Nonpathogen - hypothetical protein Nham_1414 1 None None None 92118588 Nonpathogen - hypothetical protein Nham_3121 10 None None None 92117842 Nonpathogen - hypothetical protein Nham_2319 3 None None None 92116327 Common - secretion protein HlyD Nham_0711 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92119045 Nonpathogen - hypothetical protein Nham_3586 2 None None None 92118405 Nonpathogen - hypothetical protein Nham_2906 2 None None None 92118156 Common - peptidase C15, pyroglutamyl peptidase I Nham_2644 44 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 92116603 Common - glycosyl hydrolase, BNR repeat Nham_1024 18 None None None 92119397 Common - transposase and inactivated derivatives-like Nham_3994 42 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115846 Common - putative amicyanin precursor protein Nham_0215 18 COG3794 PetE, Plastocyanin Energy production and conversion 92117579 Common - extracellular solute-binding protein, family 5 Nham_2050 136 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 92119409 Common - hypothetical protein Nham_4009 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 92118402 Common - bacterioferritin Nham_2903 112 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 92115798 Common - hypothetical protein Nham_0166 18 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 92118221 Common - cytochrome c oxidase, subunit I Nham_2711 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 92118724 Common - NUDIX hydrolase Nham_3259 34 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 92118117 Common - VWA containing CoxE-like Nham_2604 37 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 92116293 Common - histidinol-phosphate aminotransferase Nham_0674 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 92118905 Common - Nitrate reductase, gamma subunit Nham_3445 60 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 92118414 Common - 3-mercaptopyruvate sulfurtransferase Nham_2916 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 92117265 Common - peptidase U35, phage prohead HK97 Nham_1718 45 COG3740 COG3740, Phage head maturation protease General function prediction only 92116858 Common - NAD-dependent epimerase/dehydratase Nham_1302 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92118422 Common - hypothetical protein Nham_2924 8 None None None 92116088 Common - hypothetical protein Nham_0467 51 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92116273 Nonpathogen - hypothetical protein Nham_0654 3 None None None 92117701 Common - multi-sensor signal transduction histidine kinase Nham_2177 205 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92118625 Common - HAD-superfamily hydrolase, subfamily IIA Nham_3159 56 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 92116684 Common - elongation factor G Nham_1106 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 92117717 Nonpathogen - hypothetical protein Nham_2194 3 None None None 92116552 Common - hypothetical protein Nham_0969 17 None None None 92118250 Common - ABC transporter related Nham_2740 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 92117444 Common - response regulator receiver domain protein (CheY-like) Nham_1905 216 COG4566 TtrR, Response regulator Signal transduction mechanisms 92117604 Common - glycosyl transferase, family 39 Nham_2076 76 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 92117785 Common - dihydrodipicolinate synthase Nham_2262 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 92115793 Common - hypothetical protein Nham_0161 20 COG5488 COG5488, Integral membrane protein Function unknown 92119337 Common - hypothetical protein Nham_3917 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 92117003 Common - cation diffusion facilitator family transporter Nham_1450 208 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 92117971 Common - protein of unknown function DUF482 Nham_2450 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 92116962 Common - Excinuclease ABC, C subunit-like Nham_1409 40 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 92116499 Common - carbonic anhydrase Nham_0910 44 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 92118471 Common - protein of unknown function DUF1214 Nham_2980 42 COG5361 COG5361, Uncharacterized conserved protein Function unknown 92119404 Nonpathogen - hypothetical protein Nham_4003 2 None None None 92116454 Common - Catalase-like Nham_0854 119 COG0753 KatE, Catalase Inorganic ion transport and metabolism 92118341 Nonpathogen - hypothetical protein Nham_2840 1 None None None 92115867 Common - OmpA/MotB Nham_0236 160 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 92116960 Nonpathogen - hypothetical protein Nham_1407 2 None None None 92118082 Common - adenylosuccinate lyase Nham_2569 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 92116135 Common rplU 50S ribosomal protein L21 Nham_0514 200 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 92116939 Common fliM flagellar motor switch protein FliM Nham_1386 111 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 92116570 Common - hypothetical protein Nham_0989 102 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 92118909 Common - nitrate reductase, alpha subunit Nham_3449 103 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 92115713 Common - thioredoxin-related Nham_0081 225 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 92118029 Common - hypothetical protein Nham_2514 4 None None None 92118226 Common - protein of unknown function DUF344 Nham_2716 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 92118791 Common - hypothetical protein Nham_3328 4 None None None 92117140 Common - transcriptional regulator, MerR family Nham_1588 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 92117880 Nonpathogen - hypothetical protein Nham_2357 3 None None None 92117424 Common - hypothetical protein Nham_1883 11 COG5591 COG5591, Uncharacterized conserved protein Function unknown 92117104 Common rpsC 30S ribosomal protein S3 Nham_1551 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 92117981 Common - cytochrome oxidase assembly Nham_2460 64 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 92118887 Common - periplasmic solute binding protein Nham_3426 172 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 92119088 Common phhB pterin-4-alpha-carbinolamine dehydratase Nham_3629 99 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 92115651 Common - peptidase M22, glycoprotease Nham_0018 199 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 92118729 Common - CMP/dCMP deaminase, zinc-binding Nham_3264 193 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 92115817 Common - glutathione S-transferase-like Nham_0185 40 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92116201 Common - helicase-like Nham_0580 108 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 92118969 Common - OmpA/MotB Nham_3509 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 92116477 Common - hypothetical protein Nham_0882 12 COG3900 COG3900, Predicted periplasmic protein Function unknown 92117541 Common - Serine-type D-Ala-D-Ala carboxypeptidase Nham_2011 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 92117474 Common - Chromate transporter Nham_1938 111 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 92118914 Common - cytochrome C oxidase subunit IV Nham_3454 7 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 92119132 Common - sulfur oxidation protein Nham_3673 31 COG3258 COG3258, Cytochrome c Energy production and conversion 92117810 Common - Cyclopropane-fatty-acyl-phospholipid synthase Nham_2287 132 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 92118091 Common - hypothetical protein Nham_2578 19 None None None 92117304 Common - Sporulation related Nham_1759 18 None None None 92117743 Common - NADH dehydrogenase subunit B Nham_2220 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 92119058 Common - hypothetical protein Nham_3599 24 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 92116294 Common - hypothetical protein Nham_0675 45 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 92118778 Common - hypothetical protein Nham_3315 2 None None None 92119131 Nonpathogen - hypothetical protein Nham_3672 1 None None None 92116138 Common obgE GTPase ObgE Nham_0517 249 COG0536 Obg, Predicted GTPase General function prediction only 92116082 Common - histidine triad (HIT) protein Nham_0461 64 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 92118016 Nonpathogen - hypothetical protein Nham_2496 1 None None None 92119177 Common - PepSY-associated TM helix Nham_3721 42 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 92117653 Common - Propionyl-CoA carboxylase Nham_2125 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 92116095 Common - 3-demethylubiquinone-9 3-methyltransferase Nham_0474 129 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 92117708 Common - peptidase M48, Ste24p Nham_2184 98 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 92117404 Common - Integrase, catalytic region Nham_1859 49 None None None 92118488 Nonpathogen - hypothetical protein Nham_3004 1 None None None 92117954 Common - transcriptional regulator, XRE family Nham_2433 6 COG2944 COG2944, Predicted transcriptional regulator Transcription 92119167 Nonpathogen - hypothetical protein Nham_3710 1 None None None 92116172 Common - protein of unknown function UPF0005 Nham_0551 104 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 92117284 Common - CTP synthetase Nham_1738 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 92118972 Common tolB translocation protein TolB Nham_3512 159 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 92118216 Common - MaoC-like dehydratase Nham_2706 96 COG2030 MaoC, Acyl dehydratase Lipid metabolism 92116804 Common - 3-oxoacid CoA-transferase, subunit A Nham_1246 96 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 92117860 Nonpathogen - hypothetical protein Nham_2337 3 None None None 92118364 Nonpathogen - hypothetical protein Nham_2865 1 None None None 92117647 Common - phosphoribosylglycinamide formyltransferase Nham_2119 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 92119055 Common - major facilitator superfamily MFS_1 Nham_3596 40 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92116528 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Nham_0940 154 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 92118509 Common - glycosyl transferase, family 2 Nham_3032 159 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 92116006 Common - Leucyl aminopeptidase Nham_0384 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 92116440 Common - transposase IS116/IS110/IS902 Nham_0834 88 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117486 Nonpathogen - hypothetical protein Nham_1952 3 None None None 92116228 Common - hypothetical protein Nham_0608 31 COG1872 COG1872, Uncharacterized conserved protein Function unknown 92119376 Nonpathogen - hypothetical protein Nham_3970 1 None None None 92118614 Common - putative outer-membrane immunogenic protein precursor Nham_3147 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92117398 Common - secretion protein HlyD Nham_1853 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92115711 Common - hypothetical protein Nham_0079 23 COG3673 COG3673, Uncharacterized conserved protein Function unknown 92116545 Nonpathogen - hypothetical protein Nham_0961 1 None None None 92115649 Common - nitrogen-fixing NifU-like Nham_0016 96 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 92118803 Common - hypothetical protein Nham_3340 11 COG2261 COG2261, Predicted membrane protein Function unknown 92116239 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Nham_0620 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 92115718 Common - nitrogen regulatory protein P-II (GlnB, GlnK) Nham_0086 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 92117822 Nonpathogen - hypothetical protein Nham_2299 3 None None None 92116581 Nonpathogen - hypothetical protein Nham_1000 2 None None None 92116187 Common - YcfA-like Nham_0566 43 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 92119413 Common - ISSpo6, transposase OrfB Nham_4013 39 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117683 Common - phage integrase Nham_2157 191 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92116579 Common - two component transcriptional regulator, winged helix family Nham_0998 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92118793 Common - Phage tail protein I Nham_3330 4 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 92116168 Common - 2',5' RNA ligase Nham_0547 121 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 92118179 Nonpathogen - hypothetical protein Nham_2669 1 None None None 92116146 Common - carboxyl-terminal protease Nham_0525 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 92118109 Common - transposase, IS4 Nham_2596 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117367 Common - ribonuclease, Rne/Rng family Nham_1822 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 92117071 Nonpathogen - hypothetical protein Nham_1518 3 None None None 92119060 Common - RND efflux system, outer membrane lipoprotein, NodT Nham_3601 123 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92118954 Common - DSBA oxidoreductase Nham_3494 103 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 92118112 Common - protein of unknown function DUF72 Nham_2599 87 COG1801 COG1801, Uncharacterized conserved protein Function unknown 92119423 Common - peptidase C26 Nham_4023 113 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 92115943 Nonpathogen - hypothetical protein Nham_0316 1 None None None 92117439 Common - thymidine phosphorylase Nham_1900 121 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 92118275 Common - hypothetical protein Nham_2766 2 None None None 92116723 Common - putative bacteriophage-related protein Nham_1146 19 None None None 92116022 Common - DEAD/DEAH box helicase-like Nham_0400 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 92116692 Common - phosphoglucosamine mutase Nham_1114 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 92117134 Common - SmpA/OmlA Nham_1582 23 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 92118592 Nonpathogen - Twin-arginine translocation pathway signal Nham_3125 3 None None None 92117492 Common - transposase IS116/IS110/IS902 Nham_1959 100 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118085 Common - transglutaminase-like cysteine peptidase, BTLCP Nham_2572 22 COG3672 COG3672, Predicted periplasmic protein Function unknown 92119314 Common - ISMca7, transposase Nham_3889 34 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 92118683 Common - Tetratricopeptide TPR_2 Nham_3217 144 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 92117622 Nonpathogen - hypothetical protein Nham_2094 1 None None None 92117850 Common - FeS assembly ATPase SufC Nham_2327 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 92117768 Common - major intrinsic protein Nham_2245 116 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 92118880 Common - Ornithine decarboxylase Nham_3419 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 92118891 Common - crcB protein Nham_3430 181 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 92117319 Common - hypothetical protein Nham_1774 15 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 92115682 Common - 2-polyprenylphenol 6-hydroxylase Nham_0050 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 92117138 Common - 3-oxoacyl-(acyl carrier protein) synthase III Nham_1586 214 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 92118598 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Nham_3131 110 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 92116042 Common - major facilitator superfamily MFS_1 Nham_0420 19 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92118941 Common - electron transfer flavoprotein beta-subunit Nham_3481 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 92116822 Common - putative transposase Nham_1264 9 None None None 92118827 Common - TonB-dependent receptor Nham_3366 109 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 92116807 Common - PAS/PAC sensor signal transduction histidine kinase Nham_1249 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92116637 Common - dTDP-glucose 4,6-dehydratase Nham_1058 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 92117889 Nonpathogen - hypothetical protein Nham_2366 1 None None None 92117191 Common - Glutaredoxin-related protein Nham_1641 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 92116029 Common - protein of unknown function DUF1223 Nham_0407 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 92117300 Common - exodeoxyribonuclease III (xth) Nham_1755 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 92119207 Common - fructose-1,6-bisphosphate aldolase Nham_3752 172 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 92118060 Nonpathogen - hypothetical protein Nham_2547 4 None None None 92118481 Common - potassium-transporting ATPase subunit B Nham_2993 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 92118556 Common - transcriptional regulator, CadC Nham_3088 32 COG3710 CadC, DNA-binding winged-HTH domains Transcription 92116730 Nonpathogen - hypothetical protein Nham_1154 1 None None None 92118269 Nonpathogen - hypothetical protein Nham_2760 2 None None None 92117149 Common - hypothetical protein Nham_1597 2 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 92116884 Common - FAD dependent oxidoreductase Nham_1329 107 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 92116408 Nonpathogen - hypothetical protein Nham_0799 1 None None None 92117294 Common - Septum formation initiator Nham_1748 27 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 92115764 Common - transposase IS116/IS110/IS902 Nham_0132 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117001 Common - Glutamate-ammonia-ligase adenylyltransferase Nham_1448 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 92118040 Common - hypothetical protein Nham_2527 18 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 92117214 Common - OmpA-like transmembrane region Nham_1666 26 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92116620 Common - Twin-arginine translocation pathway signal Nham_1041 120 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 92119143 Common - response regulator receiver sensor signal transduction histidine kinase Nham_3684 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 92116338 Nonpathogen - hypothetical protein Nham_0722 2 None None None 92116158 Common - dihydrolipoamide dehydrogenase Nham_0537 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 92116976 Common - hypothetical protein Nham_1423 27 COG5448 COG5448, Uncharacterized conserved protein Function unknown 92118868 Common - MscS Mechanosensitive ion channel Nham_3407 227 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 92118297 Common - IS66 Orf2 like Nham_2792 51 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115669 Common - transcriptional regulator, LysR family Nham_0036 191 COG0583 LysR, Transcriptional regulator Transcription 92116433 Nonpathogen - hypothetical protein Nham_0826 13 None None None 92117873 Common - aminodeoxychorismate lyase Nham_2350 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 92119108 Common - ABC transporter related Nham_3649 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 92116717 Common - alpha/beta hydrolase fold Nham_1140 66 COG2267 PldB, Lysophospholipase Lipid metabolism 92117884 Common - PRC-barrel Nham_2361 32 None None None 92119254 Common - PRC-barrel Nham_3814 24 None None None 92117046 Common - phosphatidylserine decarboxylase Nham_1493 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 92117494 Common - Ion transport 2 Nham_1961 21 None None None 92118392 Common thiG thiazole synthase Nham_2893 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 92119229 Nonpathogen - hypothetical protein Nham_3778 2 None None None 92116034 Nonpathogen - Heme exporter protein D (CcmD) Nham_0412 1 None None None 92115933 Common - antirestriction protein Nham_0306 49 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 92116484 Common - Pyruvate formate-lyase activating Nham_0890 113 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 92116302 Common - O-succinylhomoserine (thiol)-lyase Nham_0684 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 92119043 Nonpathogen - hypothetical protein Nham_3583 1 None None None 92116771 Nonpathogen - hypothetical protein Nham_1212 1 None None None 92119031 Nonpathogen - hypothetical protein Nham_3571 3 None None None 92116077 Common - MgtC/SapB transporter Nham_0456 118 COG1285 SapB, Uncharacterized membrane protein Function unknown 92119278 Common - hypothetical protein Nham_3844 12 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 92117676 Nonpathogen - hypothetical protein Nham_2149 1 None None None 92116737 Nonpathogen - hypothetical protein Nham_1163 2 None None None 92116653 Common - hypothetical protein Nham_1074 19 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 92116452 Nonpathogen - hypothetical protein Nham_0852 1 None None None 92116342 Common - MotA/TolQ/ExbB proton channel Nham_0728 144 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 92117806 Common - dihydroorotase Nham_2283 206 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 92118132 Nonpathogen - hypothetical protein Nham_2619 1 None None None 92117113 Common rplF 50S ribosomal protein L6 Nham_1560 242 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 92116705 Nonpathogen - hypothetical protein Nham_1127 4 None None None 92116184 Common - Uroporphyrinogen III synthase HEM4 Nham_0563 34 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 92115642 Common - Pirin-like Nham_0009 141 COG1741 COG1741, Pirin-related protein General function prediction only 92116819 Common - transposase IS3/IS911 Nham_1261 6 None None None 92115673 Common - 3-oxoacyl-(acyl carrier protein) synthase I Nham_0041 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92117454 Common - hypothetical protein Nham_1915 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 92115918 Common - putative transposase Nham_0289 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 92116232 Common - isochorismatase hydrolase Nham_0612 22 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 92119240 Common - hypothetical protein Nham_3791 30 COG5654 COG5654, Uncharacterized conserved protein Function unknown 92117898 Nonpathogen - hypothetical protein Nham_2376 1 None None None 92116357 Common - Sel1-like Nham_0743 68 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 92115684 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) Nham_0052 183 COG0756 Dut, dUTPase Nucleotide transport and metabolism 92119288 Common - hypothetical protein Nham_3854 12 None None None 92117231 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Nham_1683 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 92118188 Common - hypothetical protein Nham_2678 105 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 92116686 Common - sulphate transporter Nham_1108 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 92117030 Common moaA molybdenum cofactor biosynthesis protein A Nham_1477 199 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 92117369 Common - Penicillin-binding protein 1A Nham_1824 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 92116160 Common - hypothetical protein Nham_0539 12 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 92118921 Common - protoheme IX farnesyltransferase Nham_3461 169 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 92117506 Nonpathogen - hypothetical protein Nham_1975 2 None None None 92118579 Common - ornithine aminotransferase Nham_3111 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 92119015 Common - Patatin Nham_3555 47 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 92118676 Common glyS glycyl-tRNA synthetase subunit beta Nham_3210 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 92117994 Nonpathogen - hypothetical protein Nham_2473 1 None None None 92117916 Common - hypothetical protein Nham_2394 5 None None None 92118501 Common - metallophosphoesterase Nham_3024 87 None None None 92118917 Common - protein of unknown function DUF983 Nham_3457 26 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 92117055 Common - lipid A biosynthesis lauroyl acyltransferase Nham_1502 73 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 92116887 Common - Flagellar hook-associated protein Nham_1332 116 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 92117066 Common - TonB-dependent receptor Nham_1513 92 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92119029 Nonpathogen - hypothetical protein Nham_3569 3 None None None 92118862 Common - protein of unknown function DUF477 Nham_3401 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 92118317 Common bioD dithiobiotin synthetase Nham_2815 155 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 92118374 Common carB carbamoyl phosphate synthase large subunit Nham_2875 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 92118822 Nonpathogen - hypothetical protein Nham_3360 1 None None None 92117333 Common tatA twin argininte translocase protein A Nham_1788 93 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 92118990 Common - hypothetical protein Nham_3530 10 None None None 92116196 Nonpathogen - hypothetical protein Nham_0575 1 None None None 92118854 Nonpathogen - hypothetical protein Nham_3393 1 None None None 92118199 Common - Radical SAM Nham_2689 84 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 92117417 Common - Cys/Met metabolism pyridoxal-phosphate-dependent enzymes Nham_1875 205 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 92118936 Nonpathogen - hypothetical protein Nham_3476 3 None None None 92116517 Common - phenylacetic acid degradation B Nham_0929 38 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 92116247 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Nham_0628 175 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 92117428 Common - protein of unknown function DUF156 Nham_1887 64 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 92119295 Common - Cobyrinic acid a,c-diamide synthase Nham_3861 206 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 92116710 Common - Lytic murein transglycosylase Nham_1132 100 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 92117587 Nonpathogen - hypothetical protein Nham_2058 1 None None None 92116205 Common - Resolvase-like Nham_0585 113 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92116676 Common - isocitrate lyase Nham_1097 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 92119309 Common - protein of unknown function DUF937 Nham_3880 26 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 92116402 Nonpathogen - hypothetical protein Nham_0793 2 None None None 92118452 Common - aspartate/glutamate/uridylate kinase Nham_2956 41 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 92116596 Common - multicopper oxidase, type 2 Nham_1017 54 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 92116891 Common - hypothetical protein Nham_1336 28 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 92116615 Common - putative heat-shock protein HSP 70 Nham_1036 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 92118733 Nonpathogen - hypothetical protein Nham_3268 4 None None None 92117536 Common - hypothetical protein Nham_2006 79 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 92118058 Nonpathogen - hypothetical protein Nham_2545 1 None None None 92116748 Nonpathogen - hypothetical protein Nham_1179 2 None None None 92118061 Common - Drug resistance transporter EmrB/QacA subfamily Nham_2548 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92117876 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Nham_2353 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 92118100 Nonpathogen - hypothetical protein Nham_2587 1 None None None 92119065 Common - peptidase C14, caspase catalytic subunit p20 Nham_3606 14 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 92116913 Common - hypothetical protein Nham_1358 8 None None None 92115813 Nonpathogen - hypothetical protein Nham_0181 4 None None None 92116759 Common - N-acylneuraminate-9-phosphate synthase Nham_1196 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 92116586 Common - putative monovalent cation/H+ antiporter subunit F Nham_1006 71 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 92118445 Common - Type I secretion system ATPase, PrtD Nham_2948 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 92116792 Common rpsU 30S ribosomal protein S21 Nham_1233 38 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 92118641 Common - dienelactone hydrolase Nham_3175 16 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 92118551 Common - transposase IS3/IS911 Nham_3081 22 None None None 92118142 Common - hypothetical protein Nham_2630 4 None None None 92116741 Common - transposase and inactivated derivative Nham_1168 17 None None None 92116070 Nonpathogen - hypothetical protein Nham_0449 3 None None None 92116533 Common - beta-lactamase-like Nham_0946 187 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 92117772 Nonpathogen - hypothetical protein Nham_2249 3 None None None 92116144 Common - protein of unknown function DUF163 Nham_0523 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 92119006 Common - protein of unknown function DUF1465 Nham_3546 19 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 92116923 Nonpathogen - hypothetical protein Nham_1368 8 None None None 92117665 Nonpathogen - hypothetical protein Nham_2137 1 None None None 92119024 Common - Sulfate adenylyltransferase, large subunit Nham_3564 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 92117015 Common - Malto-oligosyltrehalose trehalohydrolase Nham_1462 163 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 92116861 Common - DegT/DnrJ/EryC1/StrS aminotransferase Nham_1305 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 92118982 Common ruvA Holliday junction DNA helicase motor protein Nham_3522 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 92118432 Nonpathogen - hypothetical protein Nham_2935 2 None None None 92116069 Common ligD ATP-dependent DNA ligase Nham_0448 110 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 92118305 Common - hypothetical protein Nham_2803 11 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 92119300 Common - putative transcriptional regulator, CopG family Nham_3868 15 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 92116991 Common - cytochrome c-type biogenesis protein CcmE Nham_1438 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 92116409 Common - transcriptional regulator, XRE family Nham_0800 22 COG1709 COG1709, Predicted transcriptional regulator Transcription 92115969 Nonpathogen - hypothetical protein Nham_0342 1 None None None 92117948 Nonpathogen - hypothetical protein Nham_2427 4 None None None 92117189 Common - hypothetical protein Nham_1639 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 92115996 Nonpathogen - hypothetical protein Nham_0370 1 None None None 92117320 Nonpathogen - hypothetical protein Nham_1775 5 None None None 92117532 Common - DEAD/DEAH box helicase-like Nham_2002 130 COG1201 Lhr, Lhr-like helicases General function prediction only 92118609 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase Nham_3142 225 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 92116307 Nonpathogen fliH flagellar assembly protein H Nham_0689 9 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 92117680 Nonpathogen - hypothetical protein Nham_2154 1 None None None 92115894 Common - peptidase M16-like Nham_0263 194 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 92117630 Common - hypothetical protein Nham_2102 14 COG5482 COG5482, Uncharacterized conserved protein Function unknown 92117792 Nonpathogen - hypothetical protein Nham_2269 1 None None None 92118753 Nonpathogen - hypothetical protein Nham_3288 3 None None None 92118072 Common - methylmalonate-semialdehyde dehydrogenase Nham_2559 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 92119385 Common - ribonuclease BN, putative Nham_3981 51 COG1295 Rbn, Predicted membrane protein Function unknown 92115955 Nonpathogen - hypothetical protein Nham_0328 1 None None None 92118239 Common - Dihydrofolate reductase Nham_2729 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 92118295 Common - Recombinase Nham_2790 39 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 92117370 Common - peptide chain release factor 2 Nham_1825 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 92118166 Common - hypothetical protein Nham_2655 6 None None None 92115984 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Nham_0357 182 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 92118811 Nonpathogen - hypothetical protein Nham_3349 1 None None None 92118788 Common - phage major tail tube protein Nham_3325 26 COG3498 COG3498, Phage tail tube protein FII General function prediction only 92116449 Common - MaoC-like dehydratase Nham_0849 71 COG2030 MaoC, Acyl dehydratase Lipid metabolism 92118181 Common - Peptidase M20D, amidohydrolase Nham_2671 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 92117866 Common - hypothetical protein Nham_2343 86 None None None 92118139 Common - transcriptional regulator, MucR family Nham_2627 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 92116829 Common - Peptidoglycan glycosyltransferase Nham_1273 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 92118165 Common - Transglycosylase-associated protein Nham_2654 13 COG2261 COG2261, Predicted membrane protein Function unknown 92118561 Common - protein of unknown function DUF152 Nham_3093 176 COG1496 COG1496, Uncharacterized conserved protein Function unknown 92115920 Common - zinc-binding protein Nham_0293 41 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 92119158 Nonpathogen - protein of unknown function DUF423 Nham_3701 1 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 92117640 Common - ribonuclease D Nham_2112 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 92117625 Common - hypothetical protein Nham_2097 19 None None None 92118521 Common - glycosyl transferase, WecB/TagA/CpsF family Nham_3044 110 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 92118153 Common - monooxygenase, FAD-binding Nham_2641 90 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 92117007 Common - Carbon-monoxide dehydrogenase Nham_1454 108 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 92118538 Common - hypothetical protein Nham_3062 14 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118399 Common - protein of unknown function DUF395, YeeE/YedE Nham_2900 58 COG2391 COG2391, Predicted transporter component General function prediction only 92117224 Common - inner-membrane translocator Nham_1676 149 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 92117247 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Nham_1700 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 92115746 Common coaE dephospho-CoA kinase Nham_0114 206 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 92117606 Common - alpha-2-macroglobulin-like Nham_2078 80 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 92118214 Common - beta-lactamase Nham_2704 136 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 92116937 Common flgF flagellar basal body rod protein FlgF Nham_1384 119 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 92115774 Common - hypothetical protein Nham_0142 3 None None None 92115858 Common - Penicillin-binding protein 1A Nham_0227 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 92117602 Common - lipid A biosynthesis-like Nham_2074 21 COG3952 COG3952, Predicted membrane protein Function unknown 92115877 Common - transposase, IS4 Nham_0246 19 None None None 92118639 Common - phosphoribosylamine--glycine ligase Nham_3173 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 92117515 Common - hypothetical protein Nham_1984 12 None None None 92116424 Nonpathogen - hypothetical protein Nham_0817 9 None None None 92117198 Common - putative signal-transduction protein with CBS domains Nham_1649 148 COG0517 COG0517, FOG: CBS domain General function prediction only 92116412 Common - DNA methylase N-4/N-6 Nham_0803 113 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 92117891 Common - Methyltransferase type 12 Nham_2368 14 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 92116125 Common - helicase-like Nham_0504 68 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 92115879 Common - Sel1-like Nham_0248 110 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 92115870 Common - putative outer membrane protein Nham_0239 23 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92118836 Common - CheW protein Nham_3375 126 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 92117909 Common - hypothetical protein Nham_2387 18 None None None 92116047 Common - perplasmic binding protein of ABC transporter Nham_0425 59 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 92118277 Common - NAD-dependent epimerase/dehydratase Nham_2768 183 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92116361 Common - MotA/TolQ/ExbB proton channel Nham_0747 125 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 92116940 Nonpathogen - hypothetical protein Nham_1387 6 None None None 92117123 Common rplQ 50S ribosomal protein L17 Nham_1570 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 92118907 Common - nitrate reductase, beta subunit Nham_3447 141 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 92116646 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Nham_1067 117 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 92116566 Common - hypothetical protein Nham_0985 10 None None None 92117443 Nonpathogen - hypothetical protein Nham_1904 1 None None None 92117372 Common - hypothetical protein Nham_1827 25 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 92116639 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Nham_1060 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 92116015 Nonpathogen - peptidase A24A, prepilin type IV Nham_0393 3 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 92116569 Nonpathogen - hypothetical protein Nham_0988 1 None None None 92117093 Common rpsL 30S ribosomal protein S12 Nham_1540 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 92116464 Common - 3-oxoacid CoA-transferase, subunit B Nham_0867 107 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 92118466 Common - hypothetical protein Nham_2975 20 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 92117083 Common rplL 50S ribosomal protein L7/L12 Nham_1530 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 92118435 Common - methionine sulfoxide reductase A Nham_2938 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 92118339 Common - zinc finger, SWIM-type Nham_2838 39 COG4279 COG4279, Uncharacterized conserved protein Function unknown 92117724 Common - TonB-dependent receptor Nham_2201 115 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 92116260 Common - GcrA cell cycle regulator Nham_0641 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 92115853 Common - acyltransferase 3 Nham_0222 33 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 92116554 Common - hypothetical protein Nham_0971 46 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 92118546 Common - transposase, IS4 Nham_3075 60 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117406 Common - phage integrase Nham_1861 88 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92118280 Common - NAD-dependent epimerase/dehydratase Nham_2771 156 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92115978 Common - inner-membrane translocator Nham_0351 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 92116786 Common - NAD(P)(+) transhydrogenase (AB-specific) Nham_1227 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 92117150 Nonpathogen - hypothetical protein Nham_1598 2 None None None 92118927 Nonpathogen - hypothetical protein Nham_3467 1 None None None 92118916 Common - Surfeit locus 1 Nham_3456 30 COG3346 COG3346, Uncharacterized conserved protein Function unknown 92116296 Common - Methionine biosynthesis MetW Nham_0677 77 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92117409 Nonpathogen - hypothetical protein Nham_1864 3 None None None 92116788 Common - NAD(P) transhydrogenase, beta subunit Nham_1229 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 92118410 Common - putative ABC transporter ATP-binding protein Nham_2911 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 92115927 Nonpathogen - hypothetical protein Nham_0300 2 None None None 92116475 Common - hypothetical protein Nham_0879 8 None None None 92115815 Common - NAD-dependent epimerase/dehydratase Nham_0183 77 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92116116 Common - BolA-like protein Nham_0495 105 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 92118654 Common hisG ATP phosphoribosyltransferase Nham_3188 159 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 92117109 Common rplX 50S ribosomal protein L24 Nham_1556 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 92116607 Nonpathogen - hypothetical protein Nham_1028 2 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 92115804 Common - sigma 54 modulation protein/ribosomal protein S30EA Nham_0172 60 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 92116316 Common - phospholipid/glycerol acyltransferase Nham_0698 92 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 92119047 Nonpathogen - hypothetical protein Nham_3588 1 None None None 92116329 Common - GCN5-related N-acetyltransferase Nham_0713 4 COG0456 RimI, Acetyltransferases General function prediction only 92118903 Common - C4-dicarboxylate transporter/malic acid transport protein Nham_3443 41 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 92116100 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Nham_0479 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 92115702 Nonpathogen - hypothetical protein Nham_0070 9 None None None 92117840 Common - DNA topoisomerase IV subunit B Nham_2317 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 92118910 Common - cytochrome c, class I Nham_3450 10 COG3474 COG3474, Cytochrome c2 Energy production and conversion 92119186 Nonpathogen - hypothetical protein Nham_3731 3 None None None 92116040 Common - Amylo-alpha-1,6-glucosidase Nham_0418 45 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 92118382 Nonpathogen - hypothetical protein Nham_2883 6 None None None 92115824 Common - major facilitator superfamily MFS_1 Nham_0192 74 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 92116945 Common flgB flagellar basal body rod protein FlgB Nham_1392 35 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 92117874 Common - 3-oxoacyl-(acyl carrier protein) synthase II Nham_2351 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92116965 Nonpathogen - hypothetical protein Nham_1412 2 None None None 92117525 Nonpathogen - Superfamily I DNA and RNA helicases-like Nham_1995 3 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 92116024 Common - signal recognition particle-docking protein FtsY Nham_0402 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 92117739 Common - NADH dehydrogenase subunit E Nham_2216 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 92116386 Common - putative hypothetical RNA methyltransferase Nham_0776 165 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 92117117 Common rplO 50S ribosomal protein L15 Nham_1564 205 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 92118844 Common - hypothetical protein Nham_3383 64 None None None 92115732 Common holA DNA polymerase III subunit delta Nham_0100 45 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 92118196 Nonpathogen - hypothetical protein Nham_2686 3 None None None 92118289 Common - NAD-dependent epimerase/dehydratase Nham_2781 207 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 92118693 Common - A/G-specific adenine glycosylase Nham_3227 208 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 92118260 Common - cold-shock DNA-binding domain protein Nham_2750 174 COG1278 CspC, Cold shock proteins Transcription 92118041 Nonpathogen - hypothetical protein Nham_2528 1 None None None 92118528 Common - hypothetical protein Nham_3051 110 None None None 92119192 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components Nham_3737 53 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 92115908 Common - OmpA-like transmembrane region Nham_0278 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92116956 Common - Penicillin-binding protein 1A Nham_1403 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 92117930 Common - Uncharacterized phage-encoded protein-like Nham_2408 17 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 92118369 Common - GatB/Yqey Nham_2870 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 92116882 Common - UspA Nham_1327 83 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92116274 Nonpathogen - hypothetical protein Nham_0655 4 None None None 92117969 Common - Endoribonuclease L-PSP Nham_2448 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 92116752 Common - Phage uncharacterized protein-like Nham_1184 31 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 92118004 Nonpathogen - hypothetical protein Nham_2483 3 None None None 92116178 Common - putative phage repressor Nham_0557 38 COG2932 COG2932, Predicted transcriptional regulator Transcription 92116486 Common - ATP synthase F1, epsilon subunit Nham_0892 176 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 92119332 Common - ribonuclease BN, putative Nham_3912 123 COG1295 Rbn, Predicted membrane protein Function unknown 92117983 Common - hypothetical protein Nham_2462 16 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 92117025 Common - ATP-binding protein involved in chromosome partitioning Nham_1472 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 92119091 Common - heat shock protein 90 Nham_3632 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 92116182 Common - O-sialoglycoprotein endopeptidase Nham_0561 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 92116137 Common - GCN5-related N-acetyltransferase Nham_0516 99 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 92116864 Common - CHRD Nham_1308 16 None None None 92115658 Common lnt apolipoprotein N-acyltransferase Nham_0025 164 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 92115644 Common - integral membrane protein MviN Nham_0011 185 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 92118348 Nonpathogen - Twin-arginine translocation pathway signal Nham_2849 1 None None None 92117902 Common - Phage-related tail fibre protein-like Nham_2380 23 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 92119354 Nonpathogen - hypothetical protein Nham_3942 2 None None None 92115660 Common trmB tRNA (guanine-N(7))-methyltransferase Nham_0027 169 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 92115635 Common - DNA polymerase III subunit beta Nham_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 92116735 Nonpathogen - hypothetical protein Nham_1160 1 None None None 92118719 Common - Double-transmembrane region-like Nham_3253 31 None None None 92115836 Nonpathogen - hypothetical protein Nham_0205 1 None None None 92117173 Common - isocitrate dehydrogenase Nham_1623 60 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 92117451 Common - putative signal-transduction protein with CBS domains Nham_1912 150 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 92118031 Common - DNA mismatch endonuclease vsr Nham_2517 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 92118866 Common - flavin reductase-like, FMN-binding Nham_3405 105 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 92115971 Common - hypothetical protein Nham_0344 51 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 92117385 Common - D-amino acid aminotransferase Nham_1840 185 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 92116203 Common - DNA methylase N-4/N-6 Nham_0582 95 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 92118353 Nonpathogen - hypothetical protein Nham_2854 1 None None None 92117543 Common - phage integrase Nham_2014 97 COG0582 XerC, Integrase DNA replication, recombination, and repair 92119212 Nonpathogen - hypothetical protein Nham_3757 2 None None None 92119335 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Nham_3915 139 COG0546 Gph, Predicted phosphatases General function prediction only 92116845 Common - DNA repair protein RecN Nham_1289 194 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 92119128 Nonpathogen - hypothetical protein Nham_3669 12 COG1416 COG1416, Uncharacterized conserved protein Function unknown 92118580 Common - YbaK/prolyl-tRNA synthetase associated region Nham_3112 29 COG2606 EbsC, Uncharacterized conserved protein Function unknown 92118776 Common - hypothetical protein Nham_3313 10 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 92116311 Common - flagellar hook capping protein Nham_0693 61 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 92118714 Nonpathogen - hypothetical protein Nham_3248 4 None None None 92118329 Common - hypothetical protein Nham_2827 8 None None None 92119260 Common - transposase IS3/IS911 Nham_3825 9 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116084 Common - conserved hypothetical protein 103 Nham_0463 186 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 92117035 Common - Glutathione reductase Nham_1482 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 92117745 Nonpathogen - hypothetical protein Nham_2222 3 None None None 92117255 Common gltA type II citrate synthase Nham_1708 193 COG0372 GltA, Citrate synthase Energy production and conversion 92117343 Common - preprotein translocase, YajC subunit Nham_1798 110 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 92119431 Nonpathogen - hypothetical protein Nham_4034 1 None None None 92116155 Common - rare lipoprotein A Nham_0534 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 92116505 Common - Twin-arginine translocation pathway signal Nham_0916 77 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 92117517 Common - hypothetical protein Nham_1986 24 COG3673 COG3673, Uncharacterized conserved protein Function unknown 92116333 Common - hypothetical protein Nham_0717 130 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92117476 Nonpathogen - hypothetical protein Nham_1940 1 None None None 92117597 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Nham_2069 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 92118121 Common - carbon monoxide dehydrogenase subunit G Nham_2608 44 COG3427 COG3427, Uncharacterized conserved protein Function unknown 92115784 Common hrcA heat-inducible transcription repressor Nham_0152 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 92118124 Common - inner-membrane translocator Nham_2611 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 92119138 Common - extracellular solute-binding protein, family 3 Nham_3679 103 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 92117706 Common hppA membrane-bound proton-translocating pyrophosphatase Nham_2182 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 92116170 Common - ABC transporter related Nham_0549 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 92116106 Common - preprotein translocase subunit SecA Nham_0485 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 92118182 Common - metallophosphoesterase Nham_2672 36 COG1409 Icc, Predicted phosphohydrolases General function prediction only 92117281 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Nham_1735 135 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 92117461 Common - ABC transporter related Nham_1922 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 92117548 Common - hypothetical protein Nham_2019 4 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 92117580 Common - AMP-dependent synthetase and ligase Nham_2051 65 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92116093 Common - aspartate kinase Nham_0472 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 92116234 Common - DNA mismatch repair protein Nham_0614 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 92117235 Common - short-chain dehydrogenase/reductase SDR Nham_1687 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 92118200 Common - amidase Nham_2690 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 92116540 Common - periplasmic binding protein Nham_0956 63 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 92118409 Common - protein of unknown function UPF0118 Nham_2910 130 COG0628 PerM, Predicted permease General function prediction only 92115913 Common - phage integrase Nham_0284 24 None None None 92116879 Common - hypothetical protein Nham_1324 57 COG0392 COG0392, Predicted integral membrane protein Function unknown 92117978 Common - CoA-binding Nham_2457 116 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 92117925 Nonpathogen - hypothetical protein Nham_2403 1 None None None 92116773 Common rpmJ 50S ribosomal protein L36 Nham_1214 63 None None None 92118247 Common - hypothetical protein Nham_2737 32 COG0824 FcbC, Predicted thioesterase General function prediction only 92115698 Common ihfB integration host factor subunit beta Nham_0066 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 92117696 Common - Tetratricopeptide TPR_2 Nham_2170 12 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 92115886 Common - Cytochrome-c oxidase Nham_0255 149 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 92118400 Common - response regulator receiver domain protein (CheY-like) Nham_2901 34 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92118973 Common - putative TolA Nham_3513 13 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 92115945 Common - Integrase, catalytic region Nham_0318 80 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118442 Common - hypothetical protein Nham_2945 6 None None None 92118623 Common - beta alanine--pyruvate transaminase Nham_3157 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 92115695 Common - tryptophan synthase subunit beta Nham_0063 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 92118110 Common - glycosyl transferase, family 39 Nham_2597 40 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 92117896 Common - phage P2 GpU Nham_2373 25 COG3499 COG3499, Phage protein U General function prediction only 92117570 Common - Allophanate hydrolase subunit 2 Nham_2041 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 92119327 Common - hypothetical protein Nham_3906 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 92115973 Common - ABC transporter related Nham_0346 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 92117819 Nonpathogen - hypothetical protein Nham_2296 2 None None None 92117577 Common - Hemimethylated DNA-binding region Nham_2048 33 COG3785 COG3785, Uncharacterized conserved protein Function unknown 92118671 Common - cytochrome c, class I Nham_3205 54 COG3474 COG3474, Cytochrome c2 Energy production and conversion 92119379 Common - amidohydrolase Nham_3973 76 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 92116280 Nonpathogen - hypothetical protein Nham_0661 4 None None None 92118689 Common - molybdopterin binding domain Nham_3223 165 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 92117268 Nonpathogen - hypothetical protein Nham_1721 1 None None None 92119118 Nonpathogen - hypothetical protein Nham_3659 3 None None None 92116038 Common - glycosyl transferase, group 1 Nham_0416 167 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92116915 Nonpathogen - hypothetical protein Nham_1360 3 None None None 92117395 Common - Heavy metal efflux pump CzcA Nham_1850 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 92115791 Common - phosphoglyceromutase Nham_0159 173 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 92116781 Common - protein of unknown function DUF882 Nham_1222 60 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 92116601 Nonpathogen - hypothetical protein Nham_1022 3 None None None 92119370 Common - hypothetical protein Nham_3962 24 COG3391 COG3391, Uncharacterized conserved protein Function unknown 92118119 Common - Carbon-monoxide dehydrogenase Nham_2606 96 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 92115680 Common - formamidopyrimidine-DNA glycosylase Nham_0048 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 92118154 Common - hypothetical protein Nham_2642 11 None None None 92117446 Common - PAS/PAC sensor signal transduction histidine kinase Nham_1907 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92118722 Common - TonB-dependent receptor, plug Nham_3257 89 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 92118017 Common - putative cytochrome P460 Nham_2497 14 None None None 92118825 Nonpathogen - hypothetical protein Nham_3363 1 None None None 92119163 Common - histidine kinase Nham_3706 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92118252 Nonpathogen - hypothetical protein Nham_2742 2 None None None 92116492 Common - IstB-like ATP-binding protein Nham_0900 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92118764 Common - RND efflux system, outer membrane lipoprotein, NodT Nham_3299 112 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92116856 Common - polysaccharide biosynthesis protein CapD Nham_1300 148 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92118332 Common - hypothetical protein Nham_2830 21 COG4717 COG4717, Uncharacterized conserved protein Function unknown 92117128 Common - ATP12 ATPase Nham_1576 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 92119362 Nonpathogen - hypothetical protein Nham_3952 1 None None None 92117715 Common - signal transduction histidine kinase Nham_2192 222 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92116974 Nonpathogen - hypothetical protein Nham_1421 6 None None None 92117691 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Nham_2165 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 92118644 Common - Three-deoxy-D-manno-octulosonic-acid transferase-like Nham_3178 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 92118564 Common - protein of unknown function DUF526 Nham_3096 34 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 92117048 Common - MotA/TolQ/ExbB proton channel Nham_1495 83 COG1291 MotA, Flagellar motor component Cell motility and secretion 92117262 Nonpathogen - hypothetical protein Nham_1715 2 None None None 92119307 Nonpathogen - protein of unknown function DUF1469 Nham_3878 4 None None None 92118281 Common - glycosyl transferase, group 1 Nham_2772 179 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92117714 Common - response regulator receiver domain protein (CheY-like) Nham_2191 98 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 92116791 Nonpathogen - hypothetical protein Nham_1232 3 None None None 92115925 Nonpathogen - hypothetical protein Nham_0298 1 None None None 92119351 Common - transposase IS116/IS110/IS902 Nham_3939 71 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116971 Common - gene transfer agent (GTA) like protein Nham_1418 15 None None None 92119064 Common - Secretion protein HlyD Nham_3605 110 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92117864 Common - permease YjgP/YjgQ Nham_2341 96 COG0795 COG0795, Predicted permeases General function prediction only 92117775 Common - Peptidase S26A, signal peptidase I Nham_2252 211 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 92116190 Common - DNA methylase N-4/N-6 Nham_0569 110 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 92116210 Nonpathogen - hypothetical protein Nham_0590 2 None None None 92118495 Common - hypothetical protein Nham_3014 33 None None None 92116321 Common - hypothetical protein Nham_0704 16 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 92119215 Nonpathogen - hypothetical protein Nham_3760 1 None None None 92119338 Nonpathogen - hypothetical protein Nham_3918 1 None None None 92119344 Nonpathogen - hypothetical protein Nham_3926 2 None None None 92119209 Common - fructose-1,6-bisphosphatase Nham_3754 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 92117063 Common - secretion protein HlyD Nham_1510 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92119394 Common - ABC transporter related Nham_3991 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 92116217 Nonpathogen - hypothetical protein Nham_0597 1 None None None 92118962 Common - Alcohol dehydrogenase GroES-like Nham_3502 115 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 92118984 Common - magnesium transporter Nham_3524 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 92117612 Common - ribonucleotide-diphosphate reductase subunit alpha Nham_2084 160 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 92118813 Nonpathogen - hypothetical protein Nham_3351 4 None None None 92115997 Nonpathogen - hypothetical protein Nham_0374 1 None None None 92116926 Nonpathogen - sigma-24 (FecI-like) Nham_1371 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92117859 Common - ABC transporter related Nham_2336 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 92117995 Nonpathogen - hypothetical protein Nham_2474 1 None None None 92119421 Common - metal dependent phosphohydrolase Nham_4021 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 92119437 Nonpathogen - hypothetical protein Nham_4040 2 None None None 92116506 Common - hypothetical protein Nham_0917 3 None None None 92117624 Nonpathogen - hypothetical protein Nham_2096 3 None None None 92116126 Common - RNA-binding S4 Nham_0505 92 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 92117616 Common - hypothetical protein Nham_2088 39 None None None 92116198 Common - plasmid maintenance system killer Nham_0577 26 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 92115859 Common - protein of unknown function DUF45 Nham_0228 104 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 92117322 Nonpathogen - hypothetical protein Nham_1777 1 None None None 92116393 Common - 3-demethylubiquinone-9 3-methyltransferase Nham_0783 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 92117808 Common - DNA processing protein DprA, putative Nham_2285 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 92118238 Common - HflK protein Nham_2728 173 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 92117331 Nonpathogen - hypothetical protein Nham_1786 3 None None None 92115686 Common - protein of unknown function UPF0079 Nham_0054 195 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 92117418 Common - hypothetical protein Nham_1876 5 None None None 92116072 Common pyrE orotate phosphoribosyltransferase Nham_0451 157 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 92119265 Nonpathogen - hypothetical protein Nham_3830 1 None None None 92116774 Common - Tetratricopeptide TPR_2 Nham_1215 39 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 92115939 Common - uncharacterized conserved protein-like Nham_0312 6 None None None 92116079 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II Nham_0458 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 92118967 Common - tRNA(Ile)-lysidine synthetase-like Nham_3507 199 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 92118688 Common - Radical SAM Nham_3222 107 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 92117508 Nonpathogen - hypothetical protein Nham_1977 2 None None None 92115902 Common - hypothetical protein Nham_0271 9 None None None 92117230 Common - NnrU Nham_1682 35 COG4094 COG4094, Predicted membrane protein Function unknown 92118302 Common - polysaccharide biosynthesis protein CapD Nham_2799 136 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 92118734 Common - bifunctional transaldolase/phosoglucose isomerase Nham_3269 187 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 92117535 Common - acyl-CoA synthetase Nham_2005 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92118073 Common - acetyl-CoA acetyltransferase Nham_2560 181 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 92118518 Common - oxidoreductase-like Nham_3041 190 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 92117556 Common - phage portal protein Nham_2027 50 COG4695 COG4695, Phage-related protein Function unknown 92118089 Nonpathogen - hypothetical protein Nham_2576 4 None None None 92117317 Nonpathogen - hypothetical protein Nham_1772 3 None None None 92117758 Common - protein of unknown function UPF0118 Nham_2235 64 COG0628 PerM, Predicted permease General function prediction only 92118195 Common - Squalene/phytoene synthase Nham_2685 81 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 92116054 Common - potassium/proton antiporter Nham_0432 123 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 92115787 Common - Chaperone DnaK Nham_0155 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 92118141 Common - hypothetical protein Nham_2629 129 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 92118019 Common - transposase, IS4 Nham_2500 19 None None None 92115708 Common rpmI 50S ribosomal protein L35 Nham_0076 134 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 92118631 Common - peptidase M16-like Nham_3165 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 92117942 Common - heat shock protein DnaJ-like Nham_2421 22 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 92119292 Nonpathogen - hypothetical protein Nham_3858 1 None None None 92117787 Nonpathogen - hypothetical protein Nham_2264 3 None None None 92116355 Common - type II secretion system protein E Nham_0741 172 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 92118373 Common - protein of unknown function DUF302 Nham_2874 37 COG3439 COG3439, Uncharacterized conserved protein Function unknown 92119290 Common - hypothetical protein Nham_3856 3 None None None 92117075 Nonpathogen - hypothetical protein Nham_1522 3 None None None 92119200 Common - hydroxymethylbutenyl pyrophosphate reductase Nham_3745 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 92118998 Common - Hydrophobe/amphiphile efflux-1 HAE1 Nham_3538 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92119152 Common truA tRNA pseudouridine synthase A Nham_3695 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 92117034 Common - hypothetical protein Nham_1481 14 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 92116406 Common - hypothetical protein Nham_0797 20 None None None 92119347 Common - PRC-barrel Nham_3931 33 None None None 92118852 Common - transposase, IS4 Nham_3391 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118943 Common - hypothetical protein Nham_3483 11 None None None 92116208 Nonpathogen - hypothetical protein Nham_0588 4 None None None 92118030 Common - tISRso5; ISRSO5-transposase protein Nham_2516 47 None None None 92117797 Nonpathogen - hypothetical protein Nham_2274 13 None None None 92116298 Common - hypothetical protein Nham_0680 30 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 92115949 Common - hypothetical protein Nham_0322 9 COG4712 COG4712, Uncharacterized protein conserved in bacteria Function unknown 92118893 Common - Superoxide dismutase Nham_3432 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 92117852 Common - aminotransferase, class V Nham_2329 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 92116254 Common - Periplasmic phosphate binding protein Nham_0635 105 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 92117644 Common - hypothetical protein Nham_2116 68 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 92116303 Nonpathogen - hypothetical protein Nham_0685 4 None None None 92119022 Common - uroporphyrin-III C-methyltransferase Nham_3562 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 92117551 Nonpathogen - Uncharacterized phage protein Nham_2022 4 None None None 92115990 Common metH B12-dependent methionine synthase Nham_0363 175 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 92115778 Common - hypothetical protein Nham_0146 152 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 92115962 Common - HNH nuclease / phage PHI-105 holin-like protein Nham_0335 4 None None None 92116318 Common - transposase, IS4 Nham_0701 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116097 Common - protein of unknown function DUF6, transmembrane Nham_0476 44 COG2510 COG2510, Predicted membrane protein Function unknown 92116309 Common fliF flagellar MS-ring protein Nham_0691 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 92115802 Common - hypothetical protein Nham_0170 10 None None None 92117482 Common - putative signal-transduction protein with CBS domains Nham_1947 141 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 92119076 Common - succinate dehydrogenase, cytochrome b subunit Nham_3617 40 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 92116430 Nonpathogen - hypothetical protein Nham_0823 7 None None None 92116594 Common - GCN5-related N-acetyltransferase Nham_1015 26 COG0456 RimI, Acetyltransferases General function prediction only 92118411 Nonpathogen - hypothetical protein Nham_2912 3 None None None 92116731 Common - ISSpo6, transposase orf A Nham_1155 19 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118754 Common - nitrate reductase, beta subunit Nham_3289 141 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 92116824 Common - CsbD-like Nham_1268 50 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 92119297 Common - hypothetical protein Nham_3863 28 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 92116651 Common - Tetratricopeptide TPR_2 Nham_1072 61 COG3899 COG3899, Predicted ATPase General function prediction only 92118114 Common - molybdopterin binding domain Nham_2601 146 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 92118067 Common - MaoC-like dehydratase Nham_2554 69 COG2030 MaoC, Acyl dehydratase Lipid metabolism 92117121 Common - 30S ribosomal protein S11 Nham_1568 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 92117875 Common acpP acyl carrier protein Nham_2352 207 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92118511 Common - glycosyl transferase, group 1 Nham_3034 10 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92117202 Common - hypothetical protein Nham_1654 179 COG0759 COG0759, Uncharacterized conserved protein Function unknown 92118566 Common - MaoC-like dehydratase Nham_3098 56 COG2030 MaoC, Acyl dehydratase Lipid metabolism 92117674 Common - cold-shock DNA-binding domain protein Nham_2147 120 COG1278 CspC, Cold shock proteins Transcription 92116154 Common - F0F1 ATP synthase subunit delta Nham_0533 186 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 92117878 Common rpsF 30S ribosomal protein S6 Nham_2355 183 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 92118842 Common - hypothetical protein Nham_3381 162 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 92117569 Common - hypothetical protein Nham_2040 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 92119085 Common - hypothetical protein Nham_3626 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 92116572 Common - TatD-related deoxyribonuclease Nham_0991 44 COG1099 COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold General function prediction only 92118721 Nonpathogen - hypothetical protein Nham_3256 3 None None None 92119246 Common - hypothetical protein Nham_3805 20 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 92117833 Common - aminotransferase Nham_2310 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 92116387 Common - hemolysin A Nham_0777 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 92119010 Common - hypothetical protein Nham_3550 131 COG1678 COG1678, Putative transcriptional regulator Transcription 92116039 Common - ABC transporter related Nham_0417 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 92117952 Common - protein of unknown function DUF218 Nham_2431 99 COG1434 COG1434, Uncharacterized conserved protein Function unknown 92118290 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Nham_2782 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 92118394 Common - hypothetical protein Nham_2895 6 None None None 92118902 Common - hypothetical protein Nham_3441 4 None None None 92118205 Common - transcriptional regulator, TetR family Nham_2695 43 COG1309 AcrR, Transcriptional regulator Transcription 92119105 Common - inner-membrane translocator Nham_3646 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 92116855 Common - RfaE bifunctional protein, domain I Nham_1299 115 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 92118299 Common - transposase, mutator type Nham_2796 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115861 Common - periplasmic sensor signal transduction histidine kinase Nham_0230 185 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92119099 Common - Biopolymer transport protein ExbD/TolR Nham_3640 122 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 92116473 Common - protein of unknown function DUF344 Nham_0877 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 92116458 Common - GCN5-related N-acetyltransferase Nham_0861 106 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 92116753 Nonpathogen - hypothetical protein Nham_1186 1 None None None 92116179 Common - Acetate--CoA ligase Nham_0558 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 92116715 Common - Glutamate synthase (ferredoxin) Nham_1138 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 92118808 Nonpathogen - hypothetical protein Nham_3346 1 None None None 92116665 Common - acetyl-CoA acetyltransferase Nham_1086 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 92118479 Common - osmosensitive K+ channel signal transduction histidine kinase Nham_2991 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 92118872 Common - FGGY-family pentulose kinase Nham_3411 182 COG1069 AraB, Ribulose kinase Energy production and conversion 92116668 Nonpathogen - hypothetical protein Nham_1089 1 None None None 92118856 Common - cytochrome c oxidoreductase subunit B Nham_3395 11 None None None 92116148 Common - dinucleoside polyphosphate hydrolase Nham_0527 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 92116493 Common - Integrase, catalytic region Nham_0901 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119151 Common fmt methionyl-tRNA formyltransferase Nham_3694 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 92118726 Common - metallophosphoesterase Nham_3261 59 COG1409 Icc, Predicted phosphohydrolases General function prediction only 92117078 Common secE preprotein translocase subunit SecE Nham_1525 23 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 92115986 Nonpathogen - hypothetical protein Nham_0359 1 None None None 92119083 Common - phosphoesterase, PA-phosphatase related Nham_3624 16 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 92115717 Common - nitrogen regulatory protein P-II (GlnB, GlnK) Nham_0085 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 92117527 Common - UvrD/REP helicase Nham_1997 226 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 92115671 Common - glutathione S-transferase-like Nham_0039 88 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 92119387 Common - transposase IS66 Nham_3983 56 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115912 Nonpathogen - hypothetical protein Nham_0283 1 None None None 92117163 Nonpathogen - hypothetical protein Nham_1613 3 None None None 92117306 Common - chromosome segregation and condensation protein ScpA Nham_1761 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 92118023 Common - RNA methyltransferase TrmH, group 3 Nham_2508 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 92117562 Common - phage transcriptional regulator, AlpA Nham_2033 11 COG3311 AlpA, Predicted transcriptional regulator Transcription 92117296 Common - pyruvate dehydrogenase subunit beta Nham_1750 210 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 92117818 Nonpathogen - hypothetical protein Nham_2295 1 None None None 92116521 Common - phenylacetic acid catabolic Nham_0933 45 COG3396 COG3396, Uncharacterized conserved protein Function unknown 92117338 Common - response regulator receiver domain protein (CheY-like) Nham_1793 63 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 92115940 Nonpathogen - hypothetical protein Nham_0313 1 None None None 92117632 Nonpathogen - hypothetical protein Nham_2104 3 None None None 92116871 Common - protein of unknown function DUF140 Nham_1315 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 92117863 Common - permease YjgP/YjgQ Nham_2340 67 COG0795 COG0795, Predicted permeases General function prediction only 92115661 Common - hypothetical protein Nham_0028 161 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 92116447 Common - Endonuclease/exonuclease/phosphatase Nham_0846 73 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 92117469 Common - CBS domain containing membrane protein Nham_1933 148 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 92116645 Common - glycosyl transferase, group 1 Nham_1066 93 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92115974 Common - band 7 protein Nham_0347 219 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 92118056 Common - Fmu (Sun) Nham_2543 205 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 92117178 Common - tISRso5; ISRSO5-transposase protein Nham_1628 47 None None None 92118434 Common - SirA-like Nham_2937 69 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 92117667 Nonpathogen - hypothetical protein Nham_2140 2 None None None 92117844 Common - DEAD/DEAH box helicase-like Nham_2321 224 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 92119251 Nonpathogen - hypothetical protein Nham_3810 3 None None None 92117766 Common - manganese transport protein MntH Nham_2243 87 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 92119415 Common - NUDIX hydrolase Nham_4015 136 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 92115726 Common - two component transcriptional regulator, winged helix family Nham_0094 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92116487 Common - calcium/proton exchanger Nham_0894 23 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 92116548 Common - ChrB domain protein Nham_0965 21 None None None 92116626 Common - hypothetical protein Nham_1047 10 None None None 92115850 Common - O-succinylhomoserine sulfhydrylase Nham_0219 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 92115738 Common trmE tRNA modification GTPase TrmE Nham_0106 221 COG0486 ThdF, Predicted GTPase General function prediction only 92115750 Common - MltA Nham_0118 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 92117315 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Nham_1770 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 92115885 Common - Invasion associated locus B Nham_0254 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 92116980 Common - hypothetical protein Nham_1427 28 None None None 92119003 Common - GCN5-related N-acetyltransferase Nham_3543 29 COG0456 RimI, Acetyltransferases General function prediction only 92117761 Common - transcriptional regulator, MarR family Nham_2238 22 COG1846 MarR, Transcriptional regulators Transcription 92117491 Nonpathogen - hypothetical protein Nham_1958 1 None None None 92119034 Common - MiaB-like tRNA modifying enzyme Nham_3574 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 92117660 Nonpathogen - hypothetical protein Nham_2132 1 None None None 92119312 Common - RNA-directed DNA polymerase (Reverse transcriptase) Nham_3886 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 92117484 Common - Heavy metal translocating P-type ATPase Nham_1949 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 92117184 Common - phosphoribosylformylglycinamidine synthase subunit PurS Nham_1634 62 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 92117101 Common rplB 50S ribosomal protein L2 Nham_1548 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 92118602 Common - molybdopterin binding domain Nham_3135 164 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 92117246 Common - phosphatidate cytidylyltransferase Nham_1699 197 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 92118952 Common - transcriptional regulator, BadM/Rrf2 family Nham_3492 161 COG1959 COG1959, Predicted transcriptional regulator Transcription 92116729 Common - signal transduction histidine kinase Nham_1153 52 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92116519 Common - Phenylacetate-CoA oxygenase, PaaJ subunit Nham_0931 42 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 92118590 Common - hypothetical protein Nham_3123 9 None None None 92116762 Common - Methyltransferase type 11 Nham_1199 4 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92117248 Common - Peptidase M50, putative membrane-associated zinc metallopeptidase Nham_1701 207 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 92116031 Common - heme exporter protein CcmA Nham_0409 246 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 92117373 Common valS valyl-tRNA synthetase Nham_1828 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92119230 Common - metallophosphoesterase Nham_3779 33 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 92116325 Common - NADH:flavin oxidoreductase/NADH oxidase Nham_0709 176 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 92117223 Common - inner-membrane translocator Nham_1675 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 92115759 Common hisE phosphoribosyl-ATP pyrophosphatase Nham_0127 90 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 92117437 Common - RNA-metabolising metallo-beta-lactamase Nham_1898 120 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 92118537 Common - hypothetical protein Nham_3061 18 None None None 92116584 Common - formamidopyrimidine-DNA glycosylase Nham_1004 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 92116702 Common - hypothetical protein Nham_1124 13 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 92119017 Common - Sulphate transport system permease protein 1 Nham_3557 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 92116747 Common groES co-chaperonin GroES Nham_1177 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 92115654 Common - tRNA-i(6)A37 modification enzyme MiaB Nham_0021 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 92119141 Common - transposase IS116/IS110/IS902 Nham_3682 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119239 Common - hypothetical protein Nham_3790 26 COG5642 COG5642, Uncharacterized conserved protein Function unknown 92115960 Common - phage Terminase Nham_0333 46 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 92118796 Common - Phage-related baseplate assembly protein V Nham_3333 14 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 92116678 Nonpathogen - hypothetical protein Nham_1099 4 None None None 92117197 Common - Rhomboid-like protein Nham_1648 17 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 92117722 Common - nuclear export factor GLE1 Nham_2199 25 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 92116613 Nonpathogen - hypothetical protein Nham_1034 1 None None None 92116683 Common - protein of unknown function DUF992 Nham_1105 12 None None None 92119148 Common - protein of unknown function DUF6, transmembrane Nham_3690 41 COG2962 RarD, Predicted permeases General function prediction only 92116543 Common - autoinducer synthesis protein Nham_0959 23 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 92118745 Common - transcriptional regulator, LysR family Nham_3280 183 COG0583 LysR, Transcriptional regulator Transcription 92118881 Common - GCN5-related N-acetyltransferase Nham_3420 80 COG3153 COG3153, Predicted acetyltransferase General function prediction only 92116694 Common - hypothetical protein Nham_1116 26 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92118957 Common - Disulphide bond formation protein DsbB Nham_3497 31 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 92116985 Nonpathogen - hypothetical protein Nham_1432 1 None None None 92116725 Nonpathogen - hypothetical protein Nham_1149 3 None None None 92117984 Common - lipopolysaccharide biosynthesis Nham_2463 75 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 92116794 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Nham_1235 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 92118026 Nonpathogen - hypothetical protein Nham_2511 8 None None None 92117464 Nonpathogen - hypothetical protein Nham_1925 10 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 92118079 Nonpathogen - hypothetical protein Nham_2566 7 None None None 92116869 Nonpathogen - hypothetical protein Nham_1313 5 None None None 92117423 Common - cytochrome B561 Nham_1882 54 COG3658 COG3658, Cytochrome b Energy production and conversion 92116560 Nonpathogen - hypothetical protein Nham_0977 1 None None None 92116738 Nonpathogen - hypothetical protein Nham_1164 1 COG4907 COG4907, Predicted membrane protein Function unknown 92117938 Common - ATP-dependent Clp protease adaptor protein ClpS Nham_2417 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 92118661 Common groES co-chaperonin GroES Nham_3195 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 92117167 Nonpathogen - hypothetical protein Nham_1617 1 None None None 92117308 Common - multiple antibiotic resistance (MarC)-related proteins Nham_1763 137 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 92118254 Common - FAD dependent oxidoreductase Nham_2744 64 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 92116110 Nonpathogen - hypothetical protein Nham_0489 6 None None None 92116175 Common - hypothetical protein Nham_0554 15 None None None 92115954 Nonpathogen - hypothetical protein Nham_0327 1 None None None 92119436 Common rpsT 30S ribosomal protein S20 Nham_4039 147 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 92118584 Nonpathogen - hypothetical protein Nham_3116 1 None None None 92118975 Common - MotA/TolQ/ExbB proton channel Nham_3515 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 92118767 Nonpathogen - hypothetical protein Nham_3303 1 None None None 92118678 Nonpathogen - hypothetical protein Nham_3212 1 None None None 92118096 Common - hypothetical protein Nham_2583 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 92116906 Nonpathogen - hypothetical protein Nham_1351 3 None None None 92116379 Common - chaperone DnaJ-like Nham_0767 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 92119066 Nonpathogen - hypothetical protein Nham_3607 3 None None None 92116222 Nonpathogen - hypothetical protein Nham_0602 3 None None None 92116924 Common - UBA/THIF-type NAD/FAD binding fold Nham_1369 95 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 92118798 Common - hypothetical protein Nham_3335 2 None None None 92117350 Common - hypothetical protein Nham_1805 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 92118740 Common - glycoside hydrolase 15-related Nham_3275 69 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 92119405 Common - DNA-directed DNA polymerase Nham_4004 177 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 92116963 Common - Phage portal protein, HK97 Nham_1410 64 COG4695 COG4695, Phage-related protein Function unknown 92117022 Common - periplasmic sensor signal transduction histidine kinase Nham_1469 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92116215 Nonpathogen - hypothetical protein Nham_0595 1 None None None 92116611 Common - transcriptional regulator, LuxR family Nham_1032 30 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 92117920 Common - NusG antitermination factor Nham_2398 79 COG0250 NusG, Transcription antiterminator Transcription 92118177 Common - hypothetical protein Nham_2667 81 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 92119400 Common - putative DNA topoisomerase I Nham_3998 45 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 92116323 Common - hypothetical protein Nham_0707 10 None None None 92117732 Common - NADH dehydrogenase subunit L Nham_2209 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 92117608 Common - putative outer-membrane protein precursor Nham_2080 19 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92119175 Common - TonB-dependent siderophore receptor Nham_3719 88 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 92117652 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Nham_2124 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 92115887 Common - Cytochrome-c oxidase Nham_0256 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 92117846 Common - HesB/YadR/YfhF Nham_2323 161 COG0316 IscA, Uncharacterized conserved protein Function unknown 92118401 Common - Oligopeptidase B Nham_2902 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 92115797 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Nham_0165 233 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 92116130 Common - nuclease (SNase-like) Nham_0509 7 None None None 92118629 Common - lipoprotein signal peptidase Nham_3163 78 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92115656 Common - protein of unknown function UPF0054 Nham_0023 202 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 92118222 Common - cytochrome c oxidase, subunit II Nham_2712 48 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 92116953 Nonpathogen - hypothetical protein Nham_1400 4 None None None 92117228 Common - peptide chain release factor 3 Nham_1680 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 92118426 Nonpathogen - hypothetical protein Nham_2928 4 None None None 92119041 Common - tRNA (guanine-N1)-methyltransferase Nham_3581 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 92119253 Nonpathogen - hypothetical protein Nham_3813 1 None None None 92116769 Common - binding-protein-dependent transport systems inner membrane component Nham_1209 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 92119330 Nonpathogen - hypothetical protein Nham_3910 3 None None None 92117704 Common - hypothetical protein Nham_2180 74 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 92117005 Common - histone-like DNA-binding protein Nham_1452 111 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 92119112 Nonpathogen - hypothetical protein Nham_3653 1 None None None 92117171 Common alaS alanyl-tRNA synthetase Nham_1621 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92117904 Common - Baseplate J-like protein Nham_2382 30 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 92119016 Common - Allergen V5/Tpx-1 related Nham_3556 55 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 92118786 Nonpathogen - hypothetical protein Nham_3323 1 None None None 92117147 Common - transposase orfA IS5 family element Nham_1595 63 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115942 Nonpathogen - hypothetical protein Nham_0315 1 None None None 92117675 Nonpathogen - hypothetical protein Nham_2148 3 COG4695 COG4695, Phage-related protein Function unknown 92118461 Common - hypothetical protein Nham_2967 6 None None None 92118864 Common - nicotinate phosphoribosyltransferase Nham_3403 59 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 92118345 Common - hypothetical protein Nham_2845 3 None None None 92119223 Common - transposase IS116/IS110/IS902 Nham_3769 69 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115692 Common - FolC bifunctional protein Nham_0060 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 92118322 Common - L-aspartate oxidase Nham_2820 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 92118212 Common - Glu/Leu/Phe/Val dehydrogenase Nham_2702 178 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 92117589 Nonpathogen - hypothetical protein Nham_2060 7 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 92117435 Common - putative phosphoketolase Nham_1896 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 92118057 Common - protein of unknown function DUF1123 Nham_2544 16 COG5331 COG5331, Uncharacterized protein conserved in bacteria Function unknown 92119137 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Nham_3678 50 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 92118086 Common - Peptidylprolyl isomerase Nham_2573 139 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 92117690 Common - acylphosphatase Nham_2164 73 COG1254 AcyP, Acylphosphatases Energy production and conversion 92116818 Nonpathogen - hypothetical protein Nham_1260 1 None None None 92116426 Nonpathogen - hypothetical protein Nham_0819 20 None None None 92117635 Common - polysaccharide deacetylase Nham_2107 85 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 92118646 Common - hypothetical protein Nham_3180 24 None None None 92116277 Common - transcriptional regulator, MarR family Nham_0658 28 COG1846 MarR, Transcriptional regulators Transcription 92117301 Common - HesB/YadR/YfhF Nham_1756 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 92118934 Common - cytochrome c, class I Nham_3474 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 92118771 Nonpathogen - hypothetical protein Nham_3307 1 None None None 92118389 Common - Lytic transglycosylase, catalytic Nham_2890 30 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 92118659 Nonpathogen - hypothetical protein Nham_3193 10 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 92117582 Common - transcription-repair coupling factor Nham_2053 216 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 92117288 Common - 7-cyano-7-deazaguanine reductase Nham_1742 130 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 92117345 Common secF preprotein translocase subunit SecF Nham_1800 204 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 92118582 Common - UspA Nham_3114 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92118621 Common hisS histidyl-tRNA synthetase Nham_3154 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92116206 Nonpathogen - hypothetical protein Nham_0586 2 None None None 92119020 Common - Thiosulphate-binding protein Nham_3560 93 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 92115693 Common - acetyl-CoA carboxylase subunit beta Nham_0061 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 92119248 Common - IS66 Orf2 like Nham_3807 51 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116893 Nonpathogen flaF flagellar biosynthesis regulatory protein FlaF Nham_1338 7 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 92118965 Common - pyruvate phosphate dikinase Nham_3505 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 92118256 Common - ribosomal L11 methyltransferase Nham_2746 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 92116120 Common - cobalt chelatase, pCobT subunit Nham_0499 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 92116460 Common - hypothetical protein Nham_0863 21 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 92118619 Nonpathogen - hypothetical protein Nham_3152 3 None None None 92116524 Common - phenylacetate-CoA ligase Nham_0936 81 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 92116390 Common - histone deacetylase superfamily Nham_0780 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 92116755 Common - ISSpo6, transposase orf A Nham_1189 19 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119050 Common leuD isopropylmalate isomerase small subunit Nham_3591 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 92117974 Common - Lytic transglycosylase, catalytic Nham_2453 26 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 92117519 Common - hypothetical protein Nham_1988 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 92119037 Common - protein of unknown function DUF541 Nham_3577 96 COG2968 COG2968, Uncharacterized conserved protein Function unknown 92118505 Nonpathogen - Methyltransferase FkbM Nham_3028 4 None None None 92118337 Nonpathogen - hypothetical protein Nham_2835 1 None None None 92117836 Common - hypothetical protein Nham_2313 13 COG3686 COG3686, Predicted membrane protein Function unknown 92118309 Common - histidine triad (HIT) protein Nham_2807 204 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 92116266 Nonpathogen - hypothetical protein Nham_0647 1 None None None 92119410 Common - FAD linked oxidase-like Nham_4010 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 92118245 Common - arylsulfate sulfotransferase-related protein Nham_2735 31 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 92118955 Common - hypothetical protein Nham_3495 9 None None None 92116438 Common - hypothetical protein Nham_0831 28 None None None 92116269 Nonpathogen - hypothetical protein Nham_0650 1 None None None 92118263 Common - S-adenosylmethionine synthetase Nham_2753 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 92117999 Nonpathogen - hypothetical protein Nham_2478 1 None None None 92116415 Common - transposase IS116/IS110/IS902 Nham_0808 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116902 Nonpathogen - hypothetical protein Nham_1347 1 None None None 92116462 Common - acetate kinase Nham_0865 161 COG0282 ackA, Acetate kinase Energy production and conversion 92119375 Common - protein of unknown function UPF0126 Nham_3969 126 COG2860 COG2860, Predicted membrane protein Function unknown 92115807 Nonpathogen - hypothetical protein Nham_0175 1 None None None 92116840 Common - cell division protein FtsQ Nham_1284 77 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 92117944 Common - pantoate--beta-alanine ligase Nham_2423 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 92116340 Nonpathogen - Invasion associated locus B Nham_0726 3 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 92116605 Nonpathogen - hypothetical protein Nham_1026 2 None None None 92116241 Common - protein of unknown function DUF1345 Nham_0622 40 COG4291 COG4291, Predicted membrane protein Function unknown 92117222 Common - ABC transporter substrate-binding protein Nham_1674 52 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 92118327 Common - hypothetical protein Nham_2825 5 None None None 92116017 Common - hypothetical protein Nham_0395 18 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 92116839 Common - D-alanine--D-alanine ligase Nham_1283 210 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 92118948 Common - PAS/PAC sensor hybrid histidine kinase Nham_3488 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 92119217 Nonpathogen - hypothetical protein Nham_3763 1 None None None 92118925 Nonpathogen - hypothetical protein Nham_3465 1 None None None 92118384 Common - Extensin-like Nham_2885 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 92116811 Common - protein of unknown function DUF1214 Nham_1253 42 COG5361 COG5361, Uncharacterized conserved protein Function unknown 92119391 Common - CsbD-like Nham_3988 56 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 92119127 Nonpathogen - protein of unknown function DUF336 Nham_3668 11 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 92117219 Common - hypothetical protein Nham_1671 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 92118330 Common - hypothetical protein Nham_2828 2 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 92118699 Common - LemA Nham_3233 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 92116380 Common - alpha/beta hydrolase fold Nham_0768 54 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 92116917 Nonpathogen - hypothetical protein Nham_1362 1 None None None 92118897 Common - cold-shock DNA-binding domain protein Nham_3436 172 COG1278 CspC, Cold shock proteins Transcription 92116883 Common - putative phosphohistidine phosphatase, SixA Nham_1328 67 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 92117646 Common - phosphoribosylaminoimidazole synthetase Nham_2118 228 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 92117389 Common - Succinate-semialdehyde dehydrogenase (NAD(P)+) Nham_1844 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 92117910 Common - hypothetical protein Nham_2388 5 None None None 92118151 Nonpathogen - hypothetical protein Nham_2639 7 None None None 92116289 Common - phospholipid/glycerol acyltransferase Nham_0670 184 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 92117937 Common - ATPase AAA-2 Nham_2416 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 92117960 Common - hypothetical protein Nham_2439 31 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 92116783 Common - two component, sigma54 specific, transcriptional regulator, Fis family Nham_1224 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92117456 Common - heat shock protein Hsp20 Nham_1917 161 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 92117918 Nonpathogen - hypothetical protein Nham_2396 3 None None None 92119221 Common - hypothetical protein Nham_3767 11 COG4544 COG4544, Uncharacterized conserved protein Function unknown 92116862 Common - integral membrane protein MviN Nham_1306 188 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 92115756 Common hisH imidazole glycerol phosphate synthase subunit HisH Nham_0124 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 92119189 Common - acyl-CoA synthetase Nham_3734 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92116068 Common - arginase Nham_0447 76 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 92118704 Common - anthranilate synthase Nham_3238 231 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 92118838 Common - hypothetical protein Nham_3377 30 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 92119194 Common - DedA Nham_3739 55 COG1238 COG1238, Predicted membrane protein Function unknown 92116368 Common - hypothetical protein Nham_0755 31 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 92118106 Common groES co-chaperonin GroES Nham_2593 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 92118664 Nonpathogen - hypothetical protein Nham_3198 3 None None None 92117848 Common - cysteine desulfurases, SufS subfamily Nham_2325 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 92116847 Common - fumarylacetoacetate (FAA) hydrolase Nham_1291 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 92118361 Common - Lytic murein transglycosylase Nham_2862 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 92115856 Common - OsmC-like protein Nham_0225 27 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 92116008 Common - type II secretion system protein Nham_0386 67 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 92117733 Common - NADH dehydrogenase subunit K Nham_2210 98 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 92118523 Nonpathogen - hypothetical protein Nham_3046 1 None None None 92118612 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Nham_3145 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 92117084 Common rpoB DNA-directed RNA polymerase subunit beta Nham_1531 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 92119210 Common - transcriptional regulator, LysR family Nham_3755 184 COG0583 LysR, Transcriptional regulator Transcription 92119119 Common - response regulator receiver (CheY-like) modulated diguanylate phosphodiesterase (EAL domain) Nham_3660 159 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 92118368 Nonpathogen - hypothetical protein Nham_2869 1 None None None 92115845 Common - hypothetical protein Nham_0214 20 COG3652 COG3652, Predicted outer membrane protein Function unknown 92118717 Common - ATPase associated with various cellular activities, AAA_3 Nham_3251 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 92115823 Common - Gamma-glutamyltransferase Nham_0191 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 92118911 Nonpathogen - hypothetical protein Nham_3451 1 None None None 92118006 Nonpathogen - hypothetical protein Nham_2485 1 None None None 92118524 Common - Type I secretion membrane fusion protein, HlyD Nham_3047 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92116508 Nonpathogen - hypothetical protein Nham_0919 1 None None None 92115838 Common - transcriptional regulator, XRE family Nham_0207 11 COG2944 COG2944, Predicted transcriptional regulator Transcription 92116556 Nonpathogen - hypothetical protein Nham_0973 1 None None None 92119353 Nonpathogen - hypothetical protein Nham_3941 1 None None None 92118355 Nonpathogen - hypothetical protein Nham_2856 1 None None None 92115872 Common - metallophosphoesterase Nham_0241 55 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 92118548 Common - hypothetical protein Nham_3077 10 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 92117537 Common - TatD-related deoxyribonuclease Nham_2007 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 92118158 Common - nitrous oxidase accessory protein Nham_2646 12 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 92115814 Nonpathogen - hypothetical protein Nham_0182 1 None None None 92116153 Common - F0F1 ATP synthase subunit alpha Nham_0532 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 92118859 Common - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Nham_3398 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 92118540 Common - hypothetical protein Nham_3065 14 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 92117803 Common - Abortive infection protein Nham_2280 24 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 92115748 Common - preprotein translocase subunit SecB Nham_0116 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 92119180 Common - phosphoesterase, PA-phosphatase related Nham_3725 42 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 92117365 Common - thiamine-monophosphate kinase Nham_1820 194 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 92116546 Common - hypothetical protein Nham_0963 127 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 92117666 Nonpathogen - hypothetical protein Nham_2138 1 None None None 92118802 Common - hypothetical protein Nham_3339 5 None None None 92118010 Common - phage major capsid protein, HK97 Nham_2489 55 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 92117377 Common - cyclase/dehydrase Nham_1832 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 92116834 Common - cell cycle protein Nham_1278 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 92116229 Common - Methylenetetrahydrofolate dehydrogenase (NADP+) Nham_0609 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 92117594 Common - RND efflux system, outer membrane lipoprotein, NodT Nham_2066 128 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 92116286 Common - ABC transporter related Nham_0667 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 92118748 Nonpathogen - cytochrome c, class I Nham_3283 5 COG3474 COG3474, Cytochrome c2 Energy production and conversion 92118129 Common - cytochrome c biogenesis protein, transmembrane region Nham_2616 110 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 92115737 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Nham_0105 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 92117095 Common - elongation factor G Nham_1542 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 92118709 Common - hypothetical protein Nham_3243 123 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 92118978 Common - hypothetical protein Nham_3518 45 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 92117753 Common tig trigger factor Nham_2230 212 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 92118918 Common - cytochrome c oxidase, subunit III Nham_3458 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 92118231 Common ilvH acetolactate synthase 3 regulatory subunit Nham_2721 190 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 92116421 Common - phage uncharacterized protein Nham_0814 31 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 92118047 Common - signal transduction histidine kinase Nham_2534 96 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 92118712 Common - coproporphyrinogen III oxidase Nham_3246 112 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 92118283 Common - transposase Nham_2774 22 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119273 Nonpathogen - hypothetical protein Nham_3839 2 None None None 92116058 Common mepA penicillin-insensitive murein endopeptidase Nham_0437 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 92115819 Common - MATE efflux family protein Nham_0187 101 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 92118939 Common - 3-hydroxybutyryl-CoA dehydrogenase Nham_3479 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 92118662 Common groEL chaperonin GroEL Nham_3196 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 92118455 Common - hypothetical protein Nham_2959 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 92115843 Nonpathogen - hypothetical protein Nham_0212 3 None None None 92119036 Nonpathogen - transcription activator, effector binding Nham_3576 6 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 92116099 Common - hypothetical protein Nham_0478 26 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 92117059 Common - acyl carrier protein Nham_1506 57 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 92118736 Common - glucose-6-phosphate 1-dehydrogenase Nham_3271 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 92118996 Common - Sel1 Nham_3536 98 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 92117018 Common - Trehalose synthase-like Nham_1465 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 92119213 Nonpathogen - hypothetical protein Nham_3758 1 None None None 92119001 Common - hypothetical protein Nham_3541 28 None None None 92117990 Nonpathogen - hypothetical protein Nham_2469 2 None None None 92116471 Common - sulphate transporter Nham_0875 155 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 92117789 Common - putative porin Nham_2266 14 None None None 92118371 Common - Ferritin and Dps Nham_2872 132 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 92117894 Common - phage late control D Nham_2371 36 COG3500 COG3500, Phage protein D General function prediction only 92116151 Common - OsmC-like protein Nham_0530 100 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 92117049 Common - OmpA/MotB Nham_1496 109 COG1360 MotB, Flagellar motor protein Cell motility and secretion 92118899 Common - ISSpo6, transposase orf A Nham_3438 19 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119154 Common - succinyl-diaminopimelate desuccinylase Nham_3697 202 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 92115834 Common - glycosyl transferase, family 2 Nham_0203 50 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92119081 Common - OmpA/MotB Nham_3622 56 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 92118571 Common - 50S ribosomal protein L25/general stress protein Ctc Nham_3103 164 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 92115930 Nonpathogen - hypothetical protein Nham_0303 1 None None None 92116353 Common - General secretion pathway protein G Nham_0739 73 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 92116998 Nonpathogen - hypothetical protein Nham_1445 1 None None None 92117073 Nonpathogen - Transcription factor jumonji/aspartyl beta-hydroxylase Nham_1520 6 None None None 92116501 Common - hypothetical protein Nham_0912 21 None None None 92117413 Nonpathogen - hypothetical protein Nham_1868 1 None None None 92118542 Common - histone-like nucleoid-structuring protein H-NS Nham_3069 22 COG2916 Hns, DNA-binding protein H-NS General function prediction only 92116720 Common - response regulator receiver domain protein (CheY-like) Nham_1143 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92117313 Common - hypothetical protein Nham_1768 10 None None None 92117520 Nonpathogen - hypothetical protein Nham_1990 1 None None None 92118895 Common - Heavy metal translocating P-type ATPase Nham_3434 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 92117812 Common - replicative DNA helicase Nham_2289 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 92117658 Common - phage integrase Nham_2130 41 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92119202 Nonpathogen - hypothetical protein Nham_3747 3 None None None 92119074 Common - Alpha,alpha-trehalose-phosphate synthase Nham_3615 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 92116767 Common - ABC transporter related Nham_1207 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 92116305 Common - two component, sigma54 specific, transcriptional regulator, Fis family Nham_0687 170 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 92119294 Nonpathogen - hypothetical protein Nham_3860 2 None None None 92118210 Common - secretion protein HlyD Nham_2700 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 92119116 Common - Cupin 2, conserved barrel Nham_3657 24 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 92116373 Common - ErfK/YbiS/YcfS/YnhG Nham_0761 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92116372 Common - Extensin-like Nham_0760 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 92115687 Nonpathogen - hypothetical protein Nham_0055 3 None None None 92117188 Common - low temperature requirement A Nham_1638 29 COG4292 COG4292, Predicted membrane protein Function unknown 92119176 Nonpathogen - hypothetical protein Nham_3720 1 None None None 92116745 Common - hypothetical protein Nham_1175 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118821 Common - Uncharacterized phage-encoded protein-like Nham_3359 21 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 92117641 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit Nham_2113 94 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 92116389 Common - exodeoxyribonuclease VII small subunit Nham_0779 144 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 92118378 Common - transcriptional regulator, AsnC family Nham_2879 151 COG1522 Lrp, Transcriptional regulators Transcription 92118036 Nonpathogen - hypothetical protein Nham_2523 1 None None None 92118756 Nonpathogen - hypothetical protein Nham_3291 1 None None None 92117480 Nonpathogen - hypothetical protein Nham_1944 1 None None None 92118850 Common - protein of unknown function DUF463, YcjX-like protein Nham_3389 42 COG3106 COG3106, Predicted ATPase General function prediction only 92117906 Common - Phage-related baseplate assembly protein V Nham_2384 13 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 92117777 Common - pyridoxal phosphate biosynthetic protein PdxJ Nham_2254 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 92116436 Nonpathogen - hypothetical protein Nham_0829 1 None None None 92117354 Common - NADH dehydrogenase Nham_1809 39 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 92115999 Common - cytochrome c, class I Nham_0377 54 COG3474 COG3474, Cytochrome c2 Energy production and conversion 92116212 Nonpathogen - hypothetical protein Nham_0592 1 None None None 92117061 Common - protein of unknown function DUF87 Nham_1508 79 COG0433 COG0433, Predicted ATPase General function prediction only 92115964 Common - phage major capsid protein, HK97 Nham_0337 59 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 92117453 Common - CHAD Nham_1914 20 COG5607 COG5607, Uncharacterized conserved protein Function unknown 92118986 Common - protein of unknown function DUF1130 Nham_3526 45 COG5483 COG5483, Uncharacterized conserved protein Function unknown 92117067 Common - putative hydroxylase Nham_1514 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 92118815 Nonpathogen - hypothetical protein Nham_3353 2 None None None 92118458 Common - Uroporphyrinogen III synthase HEM4 Nham_2963 58 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 92117887 Common - hypothetical protein Nham_2364 2 None None None 92116163 Common kgd alpha-ketoglutarate decarboxylase Nham_0542 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 92119396 Common - hypothetical protein Nham_3993 48 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118632 Common - peptidase M16-like Nham_3166 176 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 92116574 Common - Hydrophobe/amphiphile efflux-1 HAE1 Nham_0993 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92115735 Common - Cobyrinic acid a,c-diamide synthase Nham_0103 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 92118449 Common - transcriptional regulator, ModE family Nham_2953 68 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 92119305 Nonpathogen - hypothetical protein Nham_3876 3 None None None 92118932 Nonpathogen - hypothetical protein Nham_3472 1 None None None 92118315 Nonpathogen - hypothetical protein Nham_2813 12 COG5615 COG5615, Predicted integral membrane protein Function unknown 92116866 Common - Phosphomethylpyrimidine kinase Nham_1310 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 92118883 Common - cation diffusion facilitator family transporter Nham_3422 166 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 92116928 Common - protein of unknown function DUF955 Nham_1373 20 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 92117375 Common - 3-methyladenine DNA glycosylase Nham_1830 78 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 92117567 Nonpathogen - hypothetical protein Nham_2038 3 None None None 92117158 Common - Mu-like prophage I protein Nham_1608 24 COG4388 COG4388, Mu-like prophage I protein General function prediction only 92119028 Nonpathogen - hypothetical protein Nham_3568 2 None None None 92118761 Common - two component transcriptional regulator, winged helix family Nham_3296 208 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92116352 Nonpathogen - General secretion pathway protein H Nham_0738 6 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 92117489 Nonpathogen - hypothetical protein Nham_1956 1 None None None 92116192 Nonpathogen - hypothetical protein Nham_0571 2 None None None 92115992 Common - prephenate dehydratase Nham_0365 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 92115781 Common - coproporphyrinogen III oxidase Nham_0149 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 92117614 Common - hypothetical protein Nham_2086 6 None None None 92119412 Nonpathogen - hypothetical protein Nham_4012 6 None None None 92117349 Common - tRNA (uracil-5-)-methyltransferase Gid Nham_1804 79 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 92119417 Common - hypothetical protein Nham_4017 12 None None None 92115707 Common rplT 50S ribosomal protein L20 Nham_0075 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 92116140 Nonpathogen - hypothetical protein Nham_0519 1 None None None 92118604 Common - two component transcriptional regulator, winged helix family Nham_3137 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92116219 Common - hypothetical protein Nham_0599 9 None None None 92118493 Nonpathogen - HPr kinase Nham_3012 7 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 92119062 Common - acriflavin resistance protein Nham_3603 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92116700 Common - peptidase S10, serine carboxypeptidase Nham_1122 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 92115890 Common - cytochrome C oxidase assembly protein Nham_0259 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 92117258 Common - ComEC/Rec2-related protein Nham_1711 50 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 92116919 Common - Integrase, catalytic region Nham_1364 51 None None None 92118572 Nonpathogen - hypothetical protein Nham_3104 1 None None None 92119389 Nonpathogen - hypothetical protein Nham_3986 2 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 92117807 Common - hypothetical protein Nham_2284 170 COG0344 COG0344, Predicted membrane protein Function unknown 92118161 Nonpathogen - hypothetical protein Nham_2649 3 None None None 92118162 Nonpathogen - hypothetical protein Nham_2651 1 None None None 92117712 Common - acetyl-CoA carboxylase biotin carboxylase subunit Nham_2189 232 COG0439 AccC, Biotin carboxylase Lipid metabolism 92116074 Common - DNA polymerase I Nham_0453 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 92118784 Common - phage P2 GpU Nham_3321 24 COG3499 COG3499, Phage protein U General function prediction only 92117052 Common - Rhodanese-like Nham_1499 73 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 92117161 Nonpathogen - hypothetical protein Nham_1611 1 None None None 92117271 Common - phage terminase, small subunit, putative, P27 Nham_1724 9 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 92116776 Common - alpha/beta hydrolase fold Nham_1217 109 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 92116495 Common - ABC transporter related Nham_0905 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 92116876 Common - ferredoxin Nham_1320 76 COG0633 Fdx, Ferredoxin Energy production and conversion 92118991 Common - transketolase Nham_3531 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 92119122 Common - ribonucleotide-diphosphate reductase subunit alpha Nham_3663 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 92118013 Common - Phage portal protein, HK97 Nham_2492 58 COG4695 COG4695, Phage-related protein Function unknown 92118960 Common - TonB-dependent receptor Nham_3500 120 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 92117634 Common - hypothetical protein Nham_2106 30 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92118146 Common - dihydroneopterin aldolase Nham_2634 77 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 92117997 Nonpathogen - hypothetical protein Nham_2476 1 None None None 92117688 Common - hypothetical protein Nham_2162 28 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 92118236 Common - hypothetical protein Nham_2726 12 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 92118228 Common - ABC transporter related Nham_2718 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 92116489 Common - hypothetical protein Nham_0896 20 None None None 92115959 Common - hypothetical protein Nham_0332 5 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 92116001 Common - extracellular solute-binding protein, family 5 Nham_0379 115 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 92116291 Nonpathogen - hypothetical protein Nham_0672 7 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 92118184 Common - RNA polymerase sigma factor Nham_2674 122 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 92116785 Nonpathogen - hypothetical protein Nham_1226 4 None None None 92117263 Nonpathogen - hypothetical protein Nham_1716 1 None None None 92119263 Common - hypothetical protein Nham_3828 15 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 92115724 Common - exodeoxyribonuclease III (xth) Nham_0092 194 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 92116981 Common - hypothetical protein Nham_1428 2 None None None 92117165 Common - hypothetical protein Nham_1615 3 None None None 92117662 Nonpathogen - hypothetical protein Nham_2134 1 None None None 92117558 Nonpathogen - hypothetical protein Nham_2029 1 None None None 92117176 Common - transposase, IS4 Nham_1626 18 None None None 92119310 Common - Transglycosylase-associated protein Nham_3881 42 COG2261 COG2261, Predicted membrane protein Function unknown 92117826 Nonpathogen - peptidase M23B Nham_2303 7 None None None 92118589 Nonpathogen - molybdopterin-guanine dinucleotide biosynthesis protein A Nham_3122 9 None None None 92116696 Common - phosphoserine aminotransferase Nham_1118 64 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 92117356 Common - hypothetical protein Nham_1811 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 92116328 Common - Hydrophobe/amphiphile efflux-1 HAE1 Nham_0712 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 92118512 Common - DegT/DnrJ/EryC1/StrS aminotransferase Nham_3035 199 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 92118104 Common - molybdopterin binding domain Nham_2591 161 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 92118122 Common - 3-oxoadipate enol-lactonase Nham_2609 165 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 92116658 Common - CsbD-like Nham_1079 14 None None None 92117747 Common - peptidase T Nham_2224 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 92115883 Common - Peptidase S26A, signal peptidase I Nham_0252 198 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 92116633 Common - lipopolysaccharide biosynthesis protein Nham_1054 26 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 92117861 Common - DNA polymerase III subunit chi Nham_2338 41 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 92118279 Common - Methyltransferase type 12 Nham_2770 44 None None None 92117618 Common - hypothetical protein Nham_2090 8 None None None 92117270 Nonpathogen - Uncharacterized phage protein Nham_1723 1 None None None 92118075 Common - hypothetical protein Nham_2562 8 None None None 92119094 Common - hypothetical protein Nham_3635 28 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 92117103 Common rplV 50S ribosomal protein L22 Nham_1550 215 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 92118650 Common ubiA prenyltransferase Nham_3184 161 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 92116760 Common - NUDIX hydrolase Nham_1197 5 None None None 92118768 Nonpathogen - hypothetical protein Nham_3304 3 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 92117143 Common - nuclease (SNase-like) Nham_1591 65 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 92116365 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Nham_0752 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 92118657 Common - putative periplasmic ligand-binding sensor protein Nham_3191 13 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 92118597 Common - MoeA-like, domain I and II Nham_3130 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 92119232 Common - ATPase associated with various cellular activities, AAA_5 Nham_3781 180 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 92115752 Common hslU ATP-dependent protease ATP-binding subunit Nham_0120 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 92117013 Common - Glycogen/starch/alpha-glucan phosphorylase Nham_1460 139 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 92117679 Common - phage Terminase Nham_2153 21 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 92115645 Common - tryptophanyl-tRNA synthetase Nham_0012 231 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92116987 Common - periplasmic sensor signal transduction histidine kinase Nham_1434 156 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92115659 Common - transcriptional regulator, XRE family Nham_0026 39 COG1396 HipB, Predicted transcriptional regulators Transcription 92117985 Common - polysaccharide export protein Nham_2464 95 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 92115812 Common - protein of unknown function DUF88 Nham_0180 67 COG1432 COG1432, Uncharacterized conserved protein Function unknown 92116392 Common - acyl-CoA dehydrogenase-like Nham_0782 142 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 92116826 Common - negative regulator of AmpC, AmpD Nham_1270 112 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 92117950 Nonpathogen - hypothetical protein Nham_2429 7 None None None 92116624 Common - methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor Nham_1045 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 92119171 Common - Integrase, catalytic region Nham_3714 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119237 Common - transposase, IS4 Nham_3788 74 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117553 Nonpathogen - hypothetical protein Nham_2024 4 None None None 92116727 Common - hypothetical protein Nham_1151 7 None None None 92116958 Common - major facilitator superfamily MFS_1 Nham_1405 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92119318 Common - putative transposase Nham_3895 49 None None None 92119420 Common - DNA-3-methyladenine glycosylase I Nham_4020 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 92118065 Common - ABC transporter related Nham_2552 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 92117154 Nonpathogen - hypothetical protein Nham_1603 5 None None None 92119103 Common - transcriptional regulator, LysR family Nham_3644 176 COG0583 LysR, Transcriptional regulator Transcription 92116801 Common - binding-protein-dependent transport systems inner membrane component Nham_1243 197 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 92116873 Common - Mammalian cell entry related Nham_1317 70 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 92117843 Common - hypothetical protein Nham_2320 75 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 92119039 Common rpsP 30S ribosomal protein S16 Nham_3579 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 92116346 Nonpathogen - putative general secretion pathway protein N Nham_0732 4 None None None 92118418 Nonpathogen - hypothetical protein Nham_2920 3 None None None 92118747 Common - cytochrome c, class IC Nham_3282 5 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 92115947 Nonpathogen - hypothetical protein Nham_0320 1 None None None 92119012 Common - transposase, IS4 Nham_3552 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116836 Common murC UDP-N-acetylmuramate--L-alanine ligase Nham_1280 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 92115923 Nonpathogen - hypothetical protein Nham_0296 1 None None None 92117347 Common - Squalene/phytoene synthase Nham_1802 45 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 92116598 Common - hypothetical protein Nham_1019 11 None None None 92116582 Nonpathogen - hypothetical protein Nham_1001 3 None None None 92116037 Nonpathogen - hypothetical protein Nham_0415 3 None None None 92116816 Common - transcriptional regulator, Crp/Fnr family Nham_1258 117 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92118116 Common - protein of unknown function DUF182 Nham_2603 111 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 92118270 Nonpathogen - hypothetical protein Nham_2761 1 None None None 92118906 Common - nitrate reductase molybdenum cofactor assembly chaperone Nham_3446 24 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 92117244 Common - ribosome recycling factor Nham_1697 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 92117755 Common - protein of unknown function UPF0031 Nham_2232 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 92117672 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Nham_2145 122 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 92119342 Common - Integrase, catalytic region Nham_3923 77 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117340 Common - peptidase M23B Nham_1795 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 92116456 Common - phage integrase Nham_0858 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92116469 Common - response regulator receiver domain protein (CheY-like) Nham_0873 193 COG4566 TtrR, Response regulator Signal transduction mechanisms 92116663 Common - glycosyl transferase, family 39 Nham_1084 23 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 92117817 Common - GCN5-related N-acetyltransferase Nham_2294 21 None None None 92118343 Nonpathogen - hypothetical protein Nham_2842 3 None None None 92116512 Common - hypothetical protein Nham_0923 13 None None None 92116713 Common - transposase, IS4 Nham_1135 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117729 Common - Biotin--acetyl-CoA-carboxylase ligase Nham_2206 190 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 92116395 Nonpathogen - hypothetical protein Nham_0785 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 92118945 Common - histidine kinase Nham_3485 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92118460 Common - Nitrite reductase (NAD(P)H) large subunit, NirB Nham_2965 219 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 92119244 Nonpathogen - hypothetical protein Nham_3800 7 None None None 92115715 Common - protein of unknown function DUF343 Nham_0083 102 COG2835 COG2835, Uncharacterized conserved protein Function unknown 92118686 Common - hypothetical protein Nham_3220 8 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 92117529 Common - transposase IS116/IS110/IS902 Nham_1999 69 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92117042 Common - GCN5-related N-acetyltransferase Nham_1489 45 COG0456 RimI, Acetyltransferases General function prediction only 92117290 Common - hypothetical protein Nham_1744 7 None None None 92115760 Common - pantothenate kinase Nham_0128 71 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 92115914 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Nham_0285 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 92117501 Nonpathogen - hypothetical protein Nham_1968 5 None None None 92115663 Common - hypothetical protein Nham_0030 37 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 92116052 Common radC DNA repair protein RadC Nham_0430 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 92116618 Common - (2Fe-2S)-binding Nham_1039 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 92115769 Nonpathogen - hypothetical protein Nham_0137 1 None None None 92118873 Common - hypothetical protein Nham_3412 19 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 92116733 Nonpathogen - hypothetical protein Nham_1157 2 None None None 92117959 Common - Ribonuclease R Nham_2438 192 COG0557 VacB, Exoribonuclease R Transcription 92117458 Common - GCN5-related N-acetyltransferase Nham_1919 155 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 92116523 Common - transcriptional regulator, TetR family Nham_0935 40 COG1309 AcrR, Transcriptional regulator Transcription 92117498 Common - transposase IS3/IS911 Nham_1965 20 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116698 Common - hypothetical protein Nham_1120 122 COG2606 EbsC, Uncharacterized conserved protein Function unknown 92117957 Nonpathogen - hypothetical protein Nham_2436 1 None None None 92119114 Nonpathogen - hypothetical protein Nham_3655 3 None None None 92117298 Common - dihydrolipoamide dehydrogenase Nham_1752 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 92117966 Common - DNA polymerase IV Nham_2445 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 92118473 Nonpathogen - hypothetical protein Nham_2983 2 None None None 92119358 Common - hypothetical protein Nham_3948 16 None None None 92115723 Common - outer membrane lipoprotein carrier protein LolA Nham_0091 45 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 92116860 Common - oxidoreductase-like Nham_1304 188 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 92117145 Common - hypothetical protein Nham_1593 6 None None None 92116616 Common - RNA binding S1 Nham_1037 142 COG2183 Tex, Transcriptional accessory protein Transcription 92117709 Common - DSBA oxidoreductase Nham_2185 107 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 92117980 Common - major facilitator superfamily MFS_1 Nham_2459 84 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 92117029 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Nham_1476 78 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 92119328 Common ligD ATP-dependent DNA ligase Nham_3907 76 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 92118192 Common - Squalene cyclase Nham_2682 41 COG1657 SqhC, Squalene cyclase Lipid metabolism 92118187 Common - hypothetical protein Nham_2677 13 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 92116045 Common - Carbohydrate-selective porin OprB Nham_0423 29 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 92119225 Common - Amino acid/peptide transporter Nham_3773 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 92117583 Common - protein of unknown function DUF339 Nham_2054 34 COG2938 COG2938, Uncharacterized conserved protein Function unknown 92118706 Common - cytochrome c1 Nham_3240 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 92115829 Common - Fmu (Sun) Nham_0197 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 92118900 Common - ATP-dependent DNA helicase RecQ Nham_3439 231 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 92117798 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Nham_2275 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 92117141 Nonpathogen - hypothetical protein Nham_1589 8 None None None 92115863 Common - protein of unknown function DUF1052 Nham_0232 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 92119079 Common - Allergen V5/Tpx-1 related Nham_3620 10 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 92119323 Common - transposase, IS111A/IS1328/IS1533 Nham_3900 52 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118463 Common - Carbohydrate-selective porin OprB Nham_2969 22 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 92117702 Common - indolepyruvate ferredoxin oxidoreductase Nham_2178 89 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 92116930 Nonpathogen - hypothetical protein Nham_1375 2 None None None 92118303 Common - O-antigen polymerase Nham_2801 19 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 92116253 Common - histidine kinase Nham_0634 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 92118648 Common - peptidase U62, modulator of DNA gyrase Nham_3182 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 92118088 Common - carbonic anhydrase/acetyltransferase isoleucine patch superfamily Nham_2575 206 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 92116681 Common - aspartate aminotransferase Nham_1103 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 92118508 Nonpathogen - hypothetical protein Nham_3031 1 None None None 92118886 Common - cobalamin synthesis protein, P47K Nham_3425 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 92115820 Common - hypothetical protein Nham_0188 20 COG3644 COG3644, Uncharacterized protein conserved in bacteria Function unknown 92117749 Common - Methyltransferase type 11 Nham_2226 167 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 92118258 Common - transposase, IS4 Nham_2748 41 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 92115690 Common - UvrD/REP helicase Nham_0058 207 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 92119407 Nonpathogen - hypothetical protein Nham_4007 1 None None None 92117637 Common - DoxX Nham_2109 43 COG2259 COG2259, Predicted membrane protein Function unknown 92119134 Common - sulfur oxidation protein Nham_3675 36 COG5501 COG5501, Predicted secreted protein Function unknown 92118438 Common - tyrosinase Nham_2941 18 None None None 92118387 Common - PRC-barrel Nham_2888 26 COG1873 COG1873, Uncharacterized conserved protein Function unknown 92117381 Common - signal transduction histidine kinase, nitrogen specific, NtrB Nham_1836 221 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 92118507 Nonpathogen - hypothetical protein Nham_3030 4 None None None 92117834 Nonpathogen - hypothetical protein Nham_2311 2 None None None 92116526 Common - enoyl-CoA hydratase Nham_0938 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 92116895 Nonpathogen - hypothetical protein Nham_1340 3 None None None 92117285 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Nham_1739 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 92117575 Common - Phosphatidylcholine synthase Nham_2046 23 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 92118366 Common dnaG DNA primase Nham_2867 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 92117039 Common - hypothetical protein Nham_1486 10 None None None 92117720 Common - prolyl-tRNA synthetase Nham_2197 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 92117929 Nonpathogen - hypothetical protein Nham_2407 2 None None None 92116080 Common - transcriptional regulator, AsnC family Nham_0459 153 COG1522 Lrp, Transcriptional regulators Transcription 92119053 Nonpathogen - hypothetical protein Nham_3594 4 None None None 92116867 Common - metallophosphoesterase Nham_1311 62 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 92116238 Common - putative ferric uptake regulator, FUR family Nham_0618 118 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 92117628 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Nham_2100 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 92116417 Common - cold-shock DNA-binding domain protein Nham_0810 177 COG1278 CspC, Cold shock proteins Transcription 92117764 Common - hypothetical protein Nham_2241 20 COG1714 COG1714, Predicted membrane protein/domain Function unknown 92116934 Common flgH flagellar basal body L-ring protein Nham_1381 102 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 92117259 Nonpathogen - hypothetical protein Nham_1712 1 None None None 92117824 Common - Lysine--tRNA ligase Nham_2301 200 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 92119434 Common - polysaccharide export protein Nham_4037 97 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 92116796 Common - diguanylate cyclase (GGDEF domain) Nham_1237 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 92117815 Common - Colicin V production protein Nham_2292 65 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 92115952 Common - phage integrase Nham_0325 16 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92116278 Common - Hydroxypyruvate reductase Nham_0659 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 92117466 Common - Alcohol dehydrogenase, zinc-binding Nham_1928 211 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 92117253 Common - protein of unknown function DUF1009 Nham_1706 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 92118617 Common - ribonuclease T2 Nham_3150 44 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 92116109 Common - Tyrosine recombinase XerD Nham_0488 219 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92119052 Common - aspartate-semialdehyde dehydrogenase Nham_3593 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 92118675 Nonpathogen - protein of unknown function DUF1236 Nham_3209 8 None None None 92117545 Nonpathogen - hypothetical protein Nham_2016 2 None None None 92117020 Common - 4-alpha-glucanotransferase Nham_1467 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 92117421 Common - PDZ/DHR/GLGF Nham_1880 210 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 92118039 Nonpathogen - hypothetical protein Nham_2526 1 None None None 92116943 Common fliP flagellar biosynthesis protein FliP Nham_1390 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 92117511 Nonpathogen - hypothetical protein Nham_1980 3 None None None 92118627 Common - riboflavin biosynthesis protein RibF Nham_3161 211 COG0196 RibF, FAD synthase Coenzyme metabolism 92118555 Common - Outer membrane autotransporter barrel Nham_3087 64 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 92117471 Common - UspA Nham_1935 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 92117026 Common - transposase, IS4 Nham_1473 40 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 92115795 Common rpsA 30S ribosomal protein S1 Nham_0163 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 92115988 Common - carbonic anhydrase Nham_0361 143 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 92117239 Common - transposase, IS4 Nham_1692 18 None None None 92118492 Common - hypothetical protein Nham_3011 5 None None None 92118267 Common - transposase, IS4 Nham_2758 29 None None None 92118094 Common - alpha/beta hydrolase fold Nham_2581 145 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 92116132 Common - protein of unknown function DUF937 Nham_0511 28 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 92117560 Common - RecA-family ATPase-like Nham_2031 13 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 92117433 Common - hypothetical protein Nham_1894 14 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 92119393 Common - MCP methyltransferase, CheR-type Nham_3990 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 92117182 Common - protein of unknown function DUF1476 Nham_1632 26 COG5467 COG5467, Uncharacterized conserved protein Function unknown 92116086 Common - protein of unknown function DUF985 Nham_0465 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 92117783 Common smpB SsrA-binding protein Nham_2260 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 92118407 Common - hypothetical protein Nham_2908 56 COG2862 COG2862, Predicted membrane protein Function unknown 92116112 Common - 3-dehydroquinate synthase Nham_0491 204 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 92119402 Common - phosphoesterase, PA-phosphatase related Nham_4001 4 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 92117697 Common - PRC-barrel Nham_2171 20 None None None 92118175 Nonpathogen - hypothetical protein Nham_2665 3 None None None 92116551 Nonpathogen - hypothetical protein Nham_0968 1 None None None 92117352 Common - acetyltransferase-like Nham_1807 44 COG2388 COG2388, Predicted acetyltransferase General function prediction only 92118008 Nonpathogen - hypothetical protein Nham_2487 3 None None None 92119261 Common - Integrase, catalytic region Nham_3826 138 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116743 Common - fatty acid desaturase Nham_1170 41 COG3239 DesA, Fatty acid desaturase Lipid metabolism 92117208 Common - hypothetical protein Nham_1660 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 92119096 Common - putative hydroxylase Nham_3637 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 92118690 Common - protein of unknown function, zinc metallopeptidase putative Nham_3224 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 92116428 Common - hypothetical protein Nham_0821 14 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 92118320 Common - hypothetical protein Nham_2818 63 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 92117735 Common - NADH dehydrogenase subunit I Nham_2212 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 92116622 Common - transcriptional regulator, LysR family Nham_1043 147 COG0583 LysR, Transcriptional regulator Transcription 92116890 Common flbT flagellar biosynthesis repressor FlbT Nham_1335 17 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 92118526 Nonpathogen - hypothetical protein Nham_3049 3 None None None 92115783 Common rph ribonuclease PH Nham_0151 180 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 92117234 Common engA GTP-binding protein EngA Nham_1686 231 COG1160 COG1160, Predicted GTPases General function prediction only 92115741 Common - transposase IS116/IS110/IS902 Nham_0109 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92119271 Nonpathogen - hypothetical protein Nham_3837 1 None None None 92115854 Common apaG ApaG Nham_0223 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 92115766 Nonpathogen - hypothetical protein Nham_0134 2 None None None 92115892 Common - protein of unknown function DUF983 Nham_0261 26 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 92116908 Common - putative predicted DNA methylase containing a Zn-ribbon Nham_1353 33 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 92117801 Common - 2-nitropropane dioxygenase, NPD Nham_2278 123 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 92116565 Common aroB 3-dehydroquinate synthase Nham_0984 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 92116248 Common - hypothetical protein Nham_0629 8 None None None 92115874 Common - protein of unknown function DUF6, transmembrane Nham_0243 196 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 92116104 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Nham_0483 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 92117379 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Nham_1834 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 92116503 Common - aconitate hydratase 1 Nham_0914 222 COG1048 AcnA, Aconitase A Energy production and conversion 92117086 Common - amine oxidase Nham_1533 9 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 92117710 Common - 3-dehydroquinate dehydratase Nham_2187 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 92118135 Nonpathogen - Peptidoglycan-binding domain 1 Nham_2622 6 None None None 92115831 Common - ErfK/YbiS/YcfS/YnhG Nham_0200 90 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 92118012 Nonpathogen - hypothetical protein Nham_2491 4 None None None 92117730 Common - NADH dehydrogenase subunit N Nham_2207 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 92117991 Common - phage integrase Nham_2470 60 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 92117596 Common - ABC transporter related Nham_2068 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 92116558 Common - hypothetical protein Nham_0975 69 COG2718 COG2718, Uncharacterized conserved protein Function unknown 92118636 Common - conserved hypothetical protein 95 Nham_3170 210 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 92117363 Common ribH riboflavin synthase subunit beta Nham_1818 208 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 92117090 Common - hypothetical protein Nham_1537 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92119165 Common - helicase-like Nham_3708 86 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 92118148 Common - Methylmalonyl-CoA mutase Nham_2636 108 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 92118172 Common - Enoyl-CoA hydratase/isomerase Nham_2662 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 92115773 Nonpathogen - hypothetical protein Nham_0141 1 None None None 92118285 Common - glycosyl transferase, group 1 Nham_2777 217 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 92118535 Common - transposase IS116/IS110/IS902 Nham_3058 53 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 92118045 Nonpathogen - hypothetical protein Nham_2532 2 None None None 92118963 Common - major facilitator superfamily MFS_1 Nham_3503 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 92116167 Common - AFG1-like ATPase Nham_0546 102 COG1485 COG1485, Predicted ATPase General function prediction only 92117403 Nonpathogen - hypothetical protein Nham_1858 2 None None None 92118857 Common - cold-shock DNA-binding domain protein Nham_3396 178 COG1278 CspC, Cold shock proteins Transcription 92119258 Nonpathogen - hypothetical protein Nham_3822 1 None None None 92118272 Common - glycosyltransferases-like Nham_2763 12 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 92117411 Nonpathogen - putative transposase of insertion sequence ISRm2011-2, orfA protein Nham_1866 5 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 92116842 Common - cell division protein FtsZ Nham_1286 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 92118847 Common - hypothetical protein Nham_3386 14 None None None 92116264 Common - putative transcriptional regulator, Crp/Fnr family Nham_0645 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92119284 Common - Complement C1q protein Nham_3850 11 None None None 92115937 Nonpathogen - hypothetical protein Nham_0310 1 None None None 92116592 Common - phage Tail Collar Nham_1013 30 COG4675 MdpB, Microcystin-dependent protein Function unknown 92118077 Common - Isoprenylcysteine carboxyl methyltransferase Nham_2564 16 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 92118207 Nonpathogen - hypothetical protein Nham_2697 13 None None None 92115832 Common lysK lysyl-tRNA synthetase Nham_0201 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 92116423 Nonpathogen - hypothetical protein Nham_0816 1 None None None 92118697 Common - Methyltransferase type 12 Nham_3231 15 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 92117791 Common - hypothetical protein Nham_2268 17 None None None 92115800 Common - protein of unknown function DUF1150 Nham_0168 13 COG5568 COG5568, Uncharacterized small protein Function unknown 92119197 Nonpathogen - hypothetical protein Nham_3742 3 None None None 92116019 Common - TadE-like Nham_0397 15 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 92116778 Common - protein of unknown function DUF1036 Nham_1219 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 92116243 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Nham_0624 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 92118937 Common - argininosuccinate lyase Nham_3477 222 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 92116271 Common - cyclic nucleotide-binding domain (cNMP-BD) protein Nham_0652 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 92118840 Common - hypothetical protein Nham_3379 19 None None None 92118562 Common - protein of unknown function DUF185 Nham_3094 94 COG1565 COG1565, Uncharacterized conserved protein Function unknown 92118028 Nonpathogen - hypothetical protein Nham_2513 2 None None None 92118610 Common - molybdopterin biosynthesis MoaE Nham_3143 144 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 92116643 Common - hypothetical protein Nham_1064 4 None None None 92115809 Common - OstA-like protein Nham_0177 33 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 92116885 Common - methionine sulfoxide reductase B Nham_1330 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 92116562 Common - AMP nucleosidase Nham_0980 91 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 92118820 Common - hypothetical protein Nham_3358 12 None None None 92118350 Common - plasmid maintenance system killer Nham_2851 51 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 92115638 Nonpathogen - hypothetical protein Nham_0005 8 COG4129 COG4129, Predicted membrane protein Function unknown 92118265 Common - UDP-glucose 6-dehydrogenase Nham_2755 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 92116181 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Nham_0560 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 92118923 Common - Cytochrome-c oxidase Nham_3463 149 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 92117935 Common - hypothetical protein Nham_2414 10 None None None 92116064 Common - two component transcriptional regulator, winged helix family Nham_0443 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 92116482 Common - periplasmic nitrate reductase NapE Nham_0888 9 COG4459 NapE, Periplasmic nitrate reductase system, NapE component Energy production and conversion 92117656 Nonpathogen - hypothetical protein Nham_2128 1 COG4907 COG4907, Predicted membrane protein Function unknown 92117210 Common - response regulator receiver domain protein (CheY-like) Nham_1662 218 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 92116224 Nonpathogen - hypothetical protein Nham_0604 3 None None None 92119368 Common - protein of unknown function DUF1452 Nham_3960 27 COG5478 COG5478, Predicted small integral membrane protein Function unknown 92116188 Common - protein of unknown function UPF0150 Nham_0567 50 COG1598 COG1598, Uncharacterized conserved protein Function unknown 92115904 Common - two component transcriptional regulator, LuxR family Nham_0273 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 92119147 Common - Acetoacetyl-CoA reductase Nham_3689 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 92116011 Common - pilus assembly protein CpaE Nham_0389 41 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 92119182 Common - Heavy metal translocating P-type ATPase Nham_3727 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 92117780 Common - protein of unknown function DUF88 Nham_2257 64 COG1432 COG1432, Uncharacterized conserved protein Function unknown 92118386 Common - protein of unknown function DUF1458 Nham_2887 25 COG3360 COG3360, Uncharacterized conserved protein Function unknown 92118586 Nonpathogen - hypothetical protein Nham_3119 8 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 92118357 Nonpathogen - hypothetical protein Nham_2858 5 None None None 92117740 Common - Methyltransferase FkbM Nham_2217 30 None None None 92118809 Common - toprim domain-containing protein Nham_3347 8 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 92117912 Nonpathogen - hypothetical protein Nham_2390 1 None None None 92118424 Nonpathogen - hypothetical protein Nham_2926 3 None None None 92116382 Common - chorismate synthase Nham_0770 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 92116951 Common - multi-sensor hybrid histidine kinase Nham_1398 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 92118489 Nonpathogen - hypothetical protein Nham_3005 1 None None None 92119125 Common - transcriptional regulator, MarR family Nham_3666 54 COG1846 MarR, Transcriptional regulators Transcription 92116490 Nonpathogen - hypothetical protein Nham_0897 1 None None None 92118034 Common - transcriptional regulator, XRE family Nham_2521 38 COG1476 COG1476, Predicted transcriptional regulators Transcription 92116026 Nonpathogen - hypothetical protein Nham_0404 1 None None None 92116635 Common - protein of unknown function DUF23 Nham_1056 18 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 92116538 Common - transport system permease protein Nham_0954 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 92119361 Nonpathogen - hypothetical protein Nham_3951 1 None None None 92116904 Common - hypothetical protein Nham_1349 4 None None None 92116853 Common - Lipopolysaccharide heptosyltransferase II Nham_1297 104 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 92118715 Common - NUDIX hydrolase Nham_3249 125 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 162211270 Common rplM 50S ribosomal protein L13 Nham_2455 222 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 92119072 Common - HAD-superfamily hydrolase subfamily IIB Nham_3613 81 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism