Chlamydophila felis Fe/C-56, complete genome NC_007899 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 89898755 Common parB chromosome partitioning protein CF0948 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 89898438 Common ami1 N-acetylmuramoyl-L-alanine amidase CF0631 184 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 89897844 Common omp01 outer membrane protein CF0037 150 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 89898572 Common dnaK heat shock protein HSP70 cofactor CF0765 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 89898431 Common dnaQ1 DNA polymerase III subunit epsilon CF0624 187 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 89898710 Common rplN 50S ribosomal protein L14 CF0903 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 89898174 Common pepF oligopeptidase F/B CF0367 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 89898544 Common pmp18 polymorphic outer membrane protein F family CF0737 8 None None None 89898095 Common omp04 outer membrane protein CF0288 3 None None None 89898558 Pathogen - hypothetical protein CF0751 1 None None None 89898383 Common gnd 6-phosphogluconate dehydrogenase CF0576 170 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 89897928 Pathogen - hypothetical protein CF0121 2 None None None 89898112 Common lysC aspartate kinase CF0305 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 89897981 Common lysS lysyl-tRNA synthetase CF0174 236 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 89898420 Pathogen - hypothetical protein CF0613 2 None None None 89898549 Common - hypothetical protein CF0742 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 89898622 Common fusA elongation factor G CF0815 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 89898440 Pathogen - hypothetical protein CF0633 1 None None None 89898073 Common yzeB ABC transporter CF0266 157 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 89898588 Common clpP1 ATP-dependent Clp protease proteolytic subunit CF0781 212 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 89898492 Pathogen - hypothetical protein CF0685 1 None None None 89898358 Common malQ 4-alpha-glucanotransferase CF0551 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 89898413 Common tlyC2 hemolysin CF0606 189 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 89898643 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CF0836 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 89898035 Common ftsY cell division related signal recognition particle GTPase CF0228 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 89898427 Common fabI enoyl-(acyl carrier protein) reductase CF0620 162 COG0623 FabI, Enoyl- acyl-carrier-protein 89898288 Common abc1 ABC transporter CF0481 62 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 89898685 Common polA DNA polymerase I CF0878 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 89898182 Common abc1 ABC transporter CF0375 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 89898764 Pathogen - hypothetical protein CF0957 1 None None None 89898325 Common - hypothetical protein CF0518 3 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 89898105 Common bioB biotin synthase CF0298 172 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 89898078 Common - hypothetical protein CF0271 5 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 89898169 Common rhaT2 transporter CF0362 31 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 89898450 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C CF0643 44 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 89897853 Common sdhB succinate dehydrogenase iron-sulfur subunit CF0046 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 89898457 Common pplD3 phospholipase D proteinase CF0650 87 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 89898779 Pathogen - hypothetical protein CF0972 3 None None None 89898201 Common hhl acyltransferase CF0394 12 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 89898722 Common fmt methionyl-tRNA formyltransferase CF0915 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 89898539 Pathogen pmp14 polymorphic outer membrane protein CF0732 2 None None None 89898177 Pathogen - hypothetical protein CF0370 1 None None None 89898197 Common - hypothetical protein CF0390 20 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 89898472 Common radA DNA repair protein RadA CF0665 208 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 89897931 Common - hypothetical protein CF0124 127 COG1881 COG1881, Phospholipid-binding protein General function prediction only 89897886 Common fliF1 type III secretion flagellar biosynthesis M-ring protein CF0079 59 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 89898581 Common ebp10 hypothetical protein CF0774 8 None None None 89898057 Common mesJ PP-loop superfamily ATPase CF0250 214 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 89898219 Pathogen - hypothetical protein CF0412 2 None None None 89898595 Common kpsF sugar-phosphate isomerase-like protein CF0788 143 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 89898613 Common yebM ABC transporter of metals CF0806 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 89898368 Common smpB SsrA-binding protein CF0561 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 89898361 Common pplD1 phospholipase D CF0554 54 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 89898150 Common awa2 cell wall-associated hydrolases CF0343 6 None None None 89898394 Common kgd alpha-ketoglutarate decarboxylase CF0587 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 89898308 Common gyrA2 DNA gyrase subunit A CF0501 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 89898388 Common fer2 ferredoxin [2Fe-2S] IV CF0581 18 COG0633 Fdx, Ferredoxin Energy production and conversion 89898770 Common - hypothetical protein CF0963 8 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 89898738 Common dnaE DNA polymerase III subunit alpha CF0931 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 89898129 Common talA transaldolase B CF0322 179 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 89898055 Common - hypothetical protein CF0248 5 COG0795 COG0795, Predicted permeases General function prediction only 89898564 Common aspC L,L-diaminopimelate aminotransferase CF0757 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 89898603 Common dksA dnaK suppressor CF0796 141 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 89898175 Common - hypothetical protein CF0368 93 COG0327 COG0327, Uncharacterized conserved protein Function unknown 89898487 Common dnaJ heat shock protein dnaJ CF0680 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 89898242 Common trpA tryptophan synthase subunit alpha CF0435 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 89898517 Pathogen - hypothetical protein CF0710 3 None None None 89898592 Pathogen - hypothetical protein CF0785 1 None None None 89897836 Common ung uracil-DNA glycosylase CF0029 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 89898474 Pathogen - hypothetical protein CF0667 1 None None None 89898662 Pathogen recO DNA repair protein RecO CF0855 3 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 89898373 Common yaeM 1-deoxy-D-xylulose 5-phosphate reductoisomerase CF0566 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 89898712 Pathogen rpl29 50S ribosomal protein L29 CF0905 2 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 89898720 Common rplC 50S ribosomal protein L3 CF0913 221 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 89898490 Pathogen - hypothetical protein CF0683 1 None None None 89898351 Common truB tRNA pseudouridine synthase B CF0544 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 89897992 Common mutS DNA mismatch repair protein CF0185 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 89898523 Pathogen gatC aspartyl/glutamyl-tRNA amidotransferase subunit C CF0716 2 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 89898796 Pathogen - hypothetical protein CF0989 2 None None None 89898017 Pathogen - hypothetical protein CF0210 1 None None None 89898286 Pathogen - hypothetical protein CF0479 1 None None None 89898041 Common rmuC DNA recombination protein CF0234 141 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 89897858 Common eno phosphopyruvate hydratase CF0051 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 89898247 Common trpR Trp operon repressor CF0440 22 COG2973 TrpR, Trp operon repressor Transcription 89898697 Common gapA glyceraldehyde 3-phosphate dehydrogenase CF0890 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 89898405 Common ssb single-strand DNA-binding protein CF0598 46 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 89898460 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CF0653 214 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 161611313 Common pknD serine/threonine-protein kinase CF0334 153 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 89897851 Common sdhC subunit of succinate dehydrogenase CF0044 14 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 89898530 Common omp13 outer membrane protein CF0723 12 None None None 89898503 Common xseA exodeoxyribonuclease VII large subunit CF0696 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 89897921 Common rodA cell division related rod shape-determining membrane protein CF0114 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 89898499 Common def peptide deformylase CF0692 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 89898700 Common rps11 30S ribosomal protein S11 CF0893 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 89898338 Common pdhC branched-chain alpha-keto acid dehydrogenase subunit E2 CF0531 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 89897862 Pathogen gp6D Chlamydial plasmid protein pGP6-D-related protein CF0055 3 None None None 89897971 Common mutT NTP pyrophosphohydrolase including oxidative damage repair enzymes CF0164 25 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 89898255 Pathogen - hypothetical protein CF0448 1 None None None 89898134 Common atpA V-type ATP synthase subunit A CF0327 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 89897999 Common pgsA2 CDP-diacylglycerol/glycerol-3-P phosphatydyltransferase CF0192 190 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 89898064 Pathogen - hypothetical protein CF0257 2 None None None 89897953 Common groL2 heat shock protein HSP60 subunit CF0146 217 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 89898259 Pathogen - hypothetical protein CF0452 1 None None None 89897978 Common priA primosome assembly protein PriA CF0171 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 89898801 Common mviN endonuclease IV CF0993 101 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 89898278 Pathogen - hypothetical protein CF0471 1 None None None 89897817 Pathogen pkaA protein kinase A anchoring protein 9 CF0011 1 None None None 89898271 Common glnP ABC transporter of amino acids CF0464 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 89898675 Common - hypothetical protein CF0868 4 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 89898656 Pathogen - hypothetical protein CF0849 2 None None None 89898145 Common htrB lipid A biosynthesis lauroyl acyltransferase CF0338 85 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 89898003 Common rpsF 30S ribosomal protein S6 CF0196 96 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 89898082 Pathogen - hypothetical protein CF0275 3 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 89898753 Common dppD ABC transporter of dipeptides CF0946 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898208 Common oppC2 ABC transporter of peptides CF0401 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898269 Pathogen - hypothetical protein CF0462 2 None None None 89897945 Common hemE uroporphyrinogen decarboxylase CF0138 174 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 89898806 Common recB ATP-dependent dsDNA/ssDNA exodeoxyribonuclease V beta CF0999 213 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 89898331 Common recR recombination protein RecR CF0524 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 89898709 Common rplX 50S ribosomal protein L24 CF0902 183 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 89897960 Common mudD MurC/ddl bifunctional enzyme CF0153 220 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 89898119 Common infA translation initiation factor IF-1 CF0312 213 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 89898341 Common dnaA1 chromosomal replication initiation protein CF0534 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 89898216 Pathogen - hypothetical protein CF0409 3 None None None 89897908 Pathogen omp03 outer membrane protein ompB CF0101 2 None None None 89898114 Pathogen - hypothetical protein CF0307 1 None None None 89897983 Pathogen - hypothetical protein CF0176 1 None None None 89898783 Pathogen ebp21 hypothetical protein CF0976 3 None None None 89898586 Common ebp11 hypothetical protein CF0779 4 None None None 89898235 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein CF0428 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 89898356 Common lcrE low calcium response protein E CF0549 4 None None None 89897988 Common rpsN 30S ribosomal protein S14 CF0181 212 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 89898032 Common glmS D-fructose-6-phosphate amidotransferase CF0225 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 89898462 Pathogen - hypothetical protein CF0655 1 None None None 89897876 Pathogen omp02 outer membrane protein CF0069 3 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 89898525 Pathogen srp40 nuclear maintenance protein SRP40 CF0718 1 None None None 89898011 Pathogen plsB glycerol-3-P acyltransferase CF0204 3 None None None 89898411 Pathogen - hypothetical protein CF0604 3 None None None 89898214 Common pyrG CTP synthetase CF0407 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 89898441 Common ftsI2 cell division related penicillin-binding protein CF0634 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 89898574 Common mag 3-methyladenine DNA glycosylase CF0767 82 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 89898418 Pathogen - hypothetical protein CF0611 1 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 89898301 Pathogen zip synaptonemal complex protein CF0494 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898436 Pathogen - hypothetical protein CF0629 3 None None None 89897918 Common rsuB ribosomal large subunit pseudouridine synthase B CF0111 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 89898097 Common aroB 3-dehydroquinate synthase CF0290 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 89898124 Common rplA 50S ribosomal protein L1 CF0317 247 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 89898583 Common - hypothetical protein CF0776 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 89898542 Common pmp16 polymorphic outer membrane protein E family CF0735 9 None None None 89897867 Pathogen srpA3 wall surface anchor family protein CF0060 2 None None None 89898611 Common thiE thiamine-phosphate pyrophosphorylase CF0804 178 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 89898179 Common - hypothetical protein CF0372 46 COG1259 COG1259, Uncharacterized conserved protein Function unknown 89898744 Common dacF penicillin-binding protein 5 CF0937 149 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 89898155 Common lepB signal peptidase I CF0348 121 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 89898028 Common lpxB lipid-A-disaccharide synthase CF0221 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 89897841 Common ahpC thio-specific antioxidant peroxidase CF0034 228 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 89898724 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase CF0917 185 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 89898672 Common oppA1 ABC transporter periplasmic oligopeptide binding lipoprotein component CF0865 137 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 89898180 Common yqgE hypothetical protein CF0373 130 COG1678 COG1678, Putative transcriptional regulator Transcription 89898811 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A CF1004 41 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 89898217 Common mta bifunctional nucleosidase CF0410 28 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 89898021 Pathogen - hypothetical protein CF0214 1 None None None 89898294 Common ydaO PP-loop type ATPase CF0487 165 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 89898344 Pathogen - hypothetical protein CF0537 2 None None None 89898597 Common gltT glutamate symporter CF0790 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 89898392 Common - hypothetical protein CF0585 166 COG1496 COG1496, Uncharacterized conserved protein Function unknown 89898736 Pathogen - hypothetical protein CF0929 1 None None None 89898084 Pathogen - hypothetical protein CF0277 2 None None None 89898203 Common ybhI dicarboxylase translocator CF0396 96 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 89898788 Pathogen - hypothetical protein CF0981 2 None None None 89898772 Common yscC type III secretion general secretion pathway protein D CF0965 132 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 89898649 Pathogen prfB peptide chain release factor 2 CF0841 1 None None None 89898425 Common - hypothetical protein CF0618 12 None None None 89898766 Common rpsB 30S ribosomal protein S2 CF0959 236 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 89898058 Common ftsH cell division related ATP-dependent zinc proteinase Clp CF0251 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 89898532 Pathogen pmp07 polymorphic outer membrane protein G/9 family CF0725 2 None None None 89898047 Common rrm3 tRNA/rRNA methyltransferase CF0240 28 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 89898189 Pathogen - hypothetical protein CF0382 1 None None None 89898099 Common aroK shikimate kinase CF0292 121 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 89898228 Pathogen - hypothetical protein CF0421 1 None None None 89898370 Common recF recombination protein F CF0563 169 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 89898505 Pathogen - hypothetical protein CF0698 1 None None None 89898107 Pathogen - hypothetical protein CF0300 2 COG5160 ULP1, Protease, Ulp1 family Posttranslational modification, protein turnover, chaperones 89897938 Common yajC preprotein translocase subunit YajC CF0131 67 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 89897884 Common fliO type III secretion system protein CF0077 36 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 89898618 Pathogen - hypothetical protein CF0811 1 None None None 89898683 Common rho transcription termination factor Rho CF0876 207 COG1158 Rho, Transcription termination factor Transcription 89898742 Common rsbW regulator of sigma subunit-histidine kinase CF0935 20 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 89897947 Common alaS alanyl-tRNA synthetase CF0140 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89897967 Pathogen mhcA1 myosin heavy chain CF0160 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898223 Pathogen - hypothetical protein CF0416 1 None None None 89898695 Common - hypothetical protein CF0888 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898048 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CF0241 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 89898195 Pathogen mhcA4 myosin heavy chain major plasmodial CF0388 2 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 89897823 Common oxr1 oxidoreductase CF0016 44 COG1478 COG1478, Uncharacterized conserved protein Function unknown 89898023 Pathogen - hypothetical protein CF0216 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898262 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit CF0455 170 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 89898638 Common yaeS undecaprenyl pyrophosphate synthetase CF0831 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 89898519 Pathogen - hypothetical protein CF0712 1 None None None 89898051 Common rpmI 50S ribosomal protein L35 CF0244 101 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 89898305 Common ses serine esterase esterase CF0498 13 COG0400 COG0400, Predicted esterase General function prediction only 89898497 Common omp09 outer membrane protein CF0690 5 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 89898245 Common trpC indole-3-glycerol phosphate synthase CF0438 218 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 89898323 Pathogen incB inclusion membrane protein CF0516 2 None None None 89898803 Common - hypothetical protein CF0996 114 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 89898794 Common yhbG ABC transporter CF0987 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 89897860 Common trpS tryptophanyl-tRNA synthetase CF0053 249 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898018 Pathogen - hypothetical protein CF0211 1 None None None 89897838 Common hamA putative deoxyribonucleotide triphosphate pyrophosphatase CF0031 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 89898485 Pathogen - hypothetical protein CF0678 1 None None None 89898510 Pathogen omp10 outer membrane protein CF0703 2 None None None 89898664 Common - hypothetical protein CF0857 25 COG1723 COG1723, Uncharacterized conserved protein Function unknown 89898749 Pathogen ebp16 hypothetical protein CF0942 1 COG5099 COG5099, RNA-binding protein of the Puf family, translational repressor Translation, ribosomal structure and biogenesis 89898353 Common ychF translation-associated GTPase CF0546 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 89898507 Common ksgA dimethyladenosine transferase CF0700 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 89897935 Pathogen - hypothetical protein CF0128 1 None None None 89898143 Common pyk pyruvate kinase CF0336 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 89898566 Common - hypothetical protein CF0759 13 COG1872 COG1872, Uncharacterized conserved protein Function unknown 89898556 Pathogen - hypothetical protein CF0749 1 None None None 89898001 Common rpl25 50S ribosomal protein L25/general stress protein Ctc CF0194 144 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 89898654 Common ycjU phosphoglycolate phosphatase CF0847 55 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 89898152 Common phoH ATPase CF0345 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 89898160 Common ffh signal recognition particle GTPase CF0353 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 89898367 Common yojL thiamine biosynthesis lipoprotein apbE precursor CF0560 131 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 89898733 Common mip FKBP-type peptidyl-prolyl cis-trans isomerase CF0926 126 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 89897893 Common trmE tRNA modification GTPase TrmE CF0086 227 COG0486 ThdF, Predicted GTPase General function prediction only 89897810 Common ispA geranylgeranyl pyrophosphate synthase CF0003 237 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 89897869 Common lcrH1 type III secretion chaperone low calcium response protein H CF0062 9 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 89898310 Pathogen - hypothetical protein CF0503 3 None None None 89898751 Common ygo phosphate permease CF0944 172 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 89898147 Common - hypothetical protein CF0340 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 89897904 Common mreB HSP70 class molecular chaperones CF0097 233 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 89898551 Common phnP2 metal dependent hydrolase of the beta-lactamase superfamily I CF0744 85 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 89898400 Common rrm6 tRNA/rRNA methyltransferase CF0593 206 COG0313 COG0313, Predicted methyltransferases General function prediction only 89898681 Common pyrF orotate phosphoribosyltransferase CF0874 97 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 89898122 Common nusG transcription antitermination protein NusG CF0315 215 COG0250 NusG, Transcription antiterminator Transcription 89897901 Common clpP ATP-dependent Clp protease proteolytic subunit CF0094 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 89898135 Common atpB V-type ATP synthase subunit B CF0328 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 89898407 Common glgX glycogen hydrolase CF0600 174 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 89897976 Common aas long chain fatty acid--[acyl-carrier-protein] ligase CF0169 213 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 89898402 Pathogen esp eggshell protein p48 CF0596 1 None None None 89897940 Pathogen hctA histone H1-like protein Hc1 CF0133 3 None None None 89897924 Common serS seryl-tRNA synthetase CF0117 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898253 Pathogen trpB2 tryptophan synthase beta chain CF0446 2 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 89898100 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CF0293 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 89898257 Pathogen - hypothetical protein CF0450 1 None None None 89898443 Common mraW S-adenosyl-methyltransferase MraW CF0636 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 89898371 Common omp08 outer membrane protein CF0564 25 COG2267 PldB, Lysophospholipase Lipid metabolism 89898702 Common secY preprotein translocase subunit SecY CF0895 237 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 89898137 Common atpI V-type ATP synthase subunit I CF0330 31 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 89898689 Common dnaB replicative DNA helicase CF0882 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 89898555 Common aroG1 3-deoxy-7-phosphoheptulonate synthase CF0748 178 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 89898297 Common ubiD aromatic acid decarboxylase CF0490 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 89898233 Pathogen - hypothetical protein CF0426 1 None None None 89898074 Common fumC fumarate hydratase CF0267 231 COG0114 FumC, Fumarase Energy production and conversion 89897914 Pathogen fliF2 type III secretion system protein CF0107 2 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 89898039 Common dapE N-succinyl-diaminopimelate deacylase CF0232 110 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 89898641 Common plsC glycerol-3-P acyltransferase CF0834 55 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 89898193 Common pkn2 serine/threonine protein kinase CF0386 131 COG1262 COG1262, Uncharacterized conserved protein Function unknown 89898130 Pathogen fer1 ferredoxin CF0323 3 None None None 89898268 Pathogen - hypothetical protein CF0461 3 None None None 89898322 Common sdt sodium-dependent transporter CF0515 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 89898060 Common rpsO 30S ribosomal protein S15 CF0253 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 89898786 Common gyrA1 DNA topoisomerase IV subunit A CF0979 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 89898109 Common phhA phenylalanine 4-monooxygenase CF0302 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 89898284 Common rplM 50S ribosomal protein L13 CF0477 225 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 89898508 Pathogen ebp08 hypothetical protein CF0701 3 None None None 89898665 Common - hypothetical protein CF0858 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 89898390 Pathogen - hypothetical protein CF0583 1 None None None 89898810 Pathogen ebp22 hypothetical protein CF1003 2 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 89898775 Pathogen ebp18 hypothetical protein CF0968 2 None None None 89898200 Common pfkA1 diphosphate--fructose-6-phosphate 1-phosphotransferase CF0393 91 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 89898399 Pathogen - hypothetical protein CF0592 1 None None None 89898422 Common - hypothetical protein CF0615 114 COG1694 MazG, Predicted pyrophosphatase General function prediction only 89898365 Pathogen mreD cell division related rod shape-determining membrane protein CF0558 3 None None None 89897857 Common rbsU sigma regulatory RsbW antagonist CF0050 103 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 89898116 Common bioY biotin synthase CF0309 79 COG1268 BioY, Uncharacterized conserved protein General function prediction only 89898698 Common rplQ 50S ribosomal protein L17 CF0891 215 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 89898304 Pathogen lyp lysophospholipase esterase CF0497 2 COG0400 COG0400, Predicted esterase General function prediction only 89898617 Common rplU 50S ribosomal protein L21 CF0810 198 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 89898384 Common tyrS tyrosyl-tRNA synthetase CF0577 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898797 Pathogen - hypothetical protein CF0990 2 None None None 89898205 Pathogen - hypothetical protein CF0398 1 None None None 89898447 Common - hypothetical protein CF0640 49 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 89898087 Common pgi glucose-6-phosphate isomerase CF0280 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 89898276 Common devB 6-phosphogluconolactonase CF0469 100 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 89898476 Pathogen - hypothetical protein CF0669 1 None None None 89898090 Pathogen - hypothetical protein CF0283 1 None None None 89898546 Pathogen - hypothetical protein CF0739 2 None None None 89897888 Common lpdA dihydrolipoamide dehydrogenase CF0081 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 89898707 Common rpsH 30S ribosomal protein S8 CF0900 219 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 89897995 Pathogen - hypothetical protein CF0188 1 None None None 89898187 Common pmp03 polymorphic outer membrane protein CF0380 11 None None None 89898429 Pathogen - hypothetical protein CF0622 2 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 89897881 Common fliR type III secretion flagellar biosynthesis inner membrane protein CF0074 108 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 89898714 Common rpsC 30S ribosomal protein S3 CF0907 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 89898792 Common aroG2 2-dehydro-3-deoxyphosphooctonate aldolase CF0985 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 89898435 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha CF0628 198 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 89898296 Common - hypothetical protein CF0489 73 COG1284 COG1284, Uncharacterized conserved protein Function unknown 89898417 Pathogen - hypothetical protein CF0610 1 None None None 89898540 Common pmp15 polymorphic outer membrane protein CF0733 12 None None None 89898575 Common - hypothetical protein CF0768 79 COG2928 COG2928, Uncharacterized conserved protein Function unknown 89897923 Pathogen - hypothetical protein CF0116 2 None None None 89897812 Common ompR two-component system regulator llrA CF0005 198 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 89897865 Common rhaT1 cationic amino acid transporter CF0058 27 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 89897808 Common - hypothetical protein CF0001 14 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 89898000 Common glgA glycogen synthase CF0193 141 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 89898773 Common pkn3 serine/threonine protein kinase CF0966 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 89898577 Pathogen - hypothetical protein CF0770 3 None None None 89898799 Pathogen - hypothetical protein CF0992 3 None None None 89898012 Common cafE ribonuclease G/E CF0205 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 89898606 Pathogen - hypothetical protein CF0799 2 None None None 89897825 Common recA recombinase A CF0018 217 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 89898496 Common - Maf-like protein CF0689 192 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 89897911 Pathogen - hypothetical protein CF0104 2 None None None 89898092 Common arcD amino acid permease CF0285 83 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 89897986 Pathogen rpmH 50S ribosomal protein L34 CF0179 2 None None None 89898009 Common ide1 insulinase family metalloproteinase CF0202 11 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 89898465 Common ptsN2 phosphotransferase system mannitol/fructose-specific Pts IIA CF0658 103 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 89898270 Common glnQ ABC transporter of amino acids CF0463 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 89898222 Common dsbB putative disulfide oxidoreductase CF0415 21 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 89898449 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B CF0642 74 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 89898678 Common rrm12 tRNA/rRNA methyltransferase CF0871 213 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 89897952 Common pph2 phosphohydrolase CF0145 31 COG1409 Icc, Predicted phosphohydrolases General function prediction only 89898805 Common - hypothetical protein CF0997 19 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 89898453 Pathogen - hypothetical protein CF0646 1 None None None 89898647 Common yhhY amino group acetyl transferase CF0840 42 COG0456 RimI, Acetyltransferases General function prediction only 89898512 Pathogen - hypothetical protein CF0705 1 None None None 89897974 Common cysQ sulfite synthesis/inositol-1-monophosphatase CF0167 143 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 89898401 Common - hypothetical protein CF0594 6 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 89898747 Pathogen - hypothetical protein CF0940 2 None None None 89897957 Common nlpD cell wall binding muramidase CF0150 40 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 89898633 Pathogen - hypothetical protein CF0826 2 None None None 89897942 Pathogen - hypothetical protein CF0135 2 None None None 89898225 Pathogen - hypothetical protein CF0418 1 None None None 89898258 Pathogen - hypothetical protein CF0451 1 None None None 89898149 Common cydB cytochrome D oxidase subunit II CF0342 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 89898333 Common omp07 outer membrane protein/ompH CF0526 12 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 89898514 Pathogen - hypothetical protein CF0707 1 None None None 89897965 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CF0158 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 89898600 Common rrm11 tRNA/rRNA methyltransferase CF0793 113 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 89898265 Pathogen incA1 inclusion membrane protein CF0458 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898652 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CF0845 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 89898185 Common clpB1 ATP-dependent Clp endopeptidase ATP-binding chain B CF0378 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 89898705 Common rplR 50S ribosomal protein L18 CF0898 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 89898274 Common oppA3 ABC transporter/periplasmic oligopeptide binding lipoprotein component CF0467 164 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 89897949 Common amn AMP nucleosidase CF0142 82 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 89898162 Common trmD tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein CF0355 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 89898669 Common ada methylated-DNA--protein-cysteine S-methyltransferase CF0862 121 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 89898006 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CF0199 156 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 89898599 Common rrm10 tRNA/rRNA methyltransferase CF0792 192 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 89897840 Common groEL chaperonin GroEL CF0033 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 89898070 Common - multiple antibiotic resistance protein CF0263 109 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 89898053 Common pheS phenylalanyl-tRNA synthetase subunit alpha CF0246 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 89897832 Common topA DNA topoisomerase I/SWI domain fusion protein CF0025 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 89898345 Common acpS 4'-phosphopantetheinyl transferase CF0538 98 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 89898569 Common proS prolyl-tRNA synthetase CF0762 237 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898386 Common rpoF RNA polymerase sigma factor sigma-28 CF0579 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 89898483 Pathogen - hypothetical protein CF0675 2 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 89898727 Common yciA acyl-CoA thioester hydrolase CF0920 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 89898758 Common csdB selenocysteine lyase CF0951 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 89898494 Common xerC site-specific tyrosine recombinase XerC CF0687 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 89898246 Common trpD anthranilate phosphoribosyltransferase CF0439 220 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 89898156 Pathogen - hypothetical protein CF0349 3 None None None 89898170 Common bal biotin apo-protein ligase-related protein CF0363 6 COG4285 COG4285, Uncharacterized conserved protein Function unknown 89898312 Common omp05 outer membrane protein CF0505 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 89898183 Common abc2 ABC transporter CF0376 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 89898320 Pathogen - hypothetical protein CF0513 2 None None None 89898740 Pathogen - hypothetical protein CF0933 3 COG4105 ComL, DNA uptake lipoprotein General function prediction only 89898716 Common rpsS 30S ribosomal protein S19 CF0909 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 89898693 Common ruvA Holliday junction DNA helicase motor protein CF0886 212 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 89898636 Pathogen - hypothetical protein CF0829 1 None None None 89897894 Common psdD phosphatidylserine decarboxylase CF0087 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 89898731 Common trxA3 thioredoxin CF0924 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 89897875 Common gspF general secretion pathway protein F CF0068 135 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 89898378 Pathogen adhS1 ABC transporter/periplasmic Mn/Zn-binding protein CF0570 1 None None None 89898030 Pathogen - hypothetical protein CF0223 1 None None None 89898534 Common pmp09 polymorphic outer membrane protein CF0727 22 None None None 89898044 Common nrdA ribonucleotide-diphosphate reductase subunit alpha CF0237 227 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 89898025 Common mhcB2 myosin heavy chain form B CF0218 69 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898289 Common - hypothetical protein CF0482 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 89898263 Common efp1 elongation factor P CF0456 214 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 89898080 Pathogen - hypothetical protein CF0273 2 None None None 89897814 Common recD1 ATP-dependent dsDNA/ssDNA exodeoxyribonuclease V alpha CF0007 122 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 89898094 Pathogen - hypothetical protein CF0287 2 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 89898089 Common mdhC malate dehydrogenase CF0282 100 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 89898812 Common hemB delta-aminolevulinic acid dehydratase CF1005 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 89898615 Common obgE GTPase ObgE CF0808 249 COG0536 Obg, Predicted GTPase General function prediction only 89898316 Common dhnA fructose-bisphosphate aldolase CF0509 64 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 89898628 Common omp15 outer membrane protein CF0821 9 None None None 89898795 Pathogen - hypothetical protein CF0988 3 None None None 89898397 Pathogen - hypothetical protein CF0590 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 89897846 Pathogen exbF energy transducer CF0039 2 None None None 89898207 Common oppD ABC transporter of peptides CF0400 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898231 Pathogen - hypothetical protein CF0424 1 None None None 89897898 Common engA GTP-binding protein EngA CF0091 222 COG1160 COG1160, Predicted GTPases General function prediction only 89897891 Common brnQ branched-chain amino acid transport system carrier protein CF0084 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 89898687 Common adt2 ADP/ATP translocase CF0880 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 89898291 Pathogen - hypothetical protein CF0484 2 None None None 89898199 Common kdtA1 3-deoxy-D-manno-octulosonic-acid transferase CF0392 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 89898553 Common artJ ABC transporter of amino acids CF0746 155 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 89897934 Common ftsK cell division related Stage III sporulation protein E CF0127 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 89898299 Common - hypothetical protein CF0492 138 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 89898634 Common recJ Mg-dependent 5'-3' ssDNA-specific exonuclease CF0827 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 89898131 Pathogen - hypothetical protein CF0324 3 None None None 89898076 Pathogen - hypothetical protein CF0269 1 None None None 89898166 Pathogen ebp06 hypothetical protein CF0359 2 None None None 89897871 Common pepP aminopeptidase P CF0064 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 89897878 Pathogen - hypothetical protein CF0071 2 None None None 89897916 Common nifS1 cysteine desulfurase CF0109 175 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 89898624 Common rpsL 30S ribosomal protein S12 CF0817 238 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 89898054 Pathogen cef calcium binding EF-hand protein precursor CF0247 2 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 89897815 Pathogen - hypothetical protein CF0008 2 None None None 89898777 Common fliI1 type III secretion system ATPase CF0970 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 89898191 Pathogen - hypothetical protein CF0384 1 None None None 89898677 Common fliY ABC transporter CF0870 51 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 89898066 Pathogen - hypothetical protein CF0259 2 None None None 89898110 Common dapB dihydrodipicolinate reductase CF0303 191 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 89898126 Common - hypothetical protein CF0319 4 None None None 89898220 Common - hypothetical protein CF0413 10 None None None 89898467 Common accD acetyl-CoA carboxylase subunit beta CF0660 220 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 89898103 Common bioD dethiobiotin synthetase CF0296 130 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 89898708 Common rplE 50S ribosomal protein L5 CF0901 244 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 89898306 Common dnaX1 DNA polymerase III subunit delta' CF0499 195 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 89898478 Common dnaX2 DNA polymerase III subunits gamma and tau CF0671 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 89898782 Common adc adenylate cyclase CF0975 11 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 89898272 Common argR transciption factor/arginine operon repressor CF0465 79 COG1438 ArgR, Arginine repressor Transcription 89897963 Pathogen - hypothetical protein CF0156 3 None None None 89898043 Pathogen - hypothetical protein CF0236 1 None None None 89897984 Common dsbD2 thioredoxin/thiol-disulfide isomerase CF0177 4 None None None 89898589 Common glyA serine hydroxymethyltransferase CF0782 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 89898548 Pathogen - hypothetical protein CF0741 3 None None None 89898579 Common tlyC3 hemolysin CF0772 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 89898282 Common ydhO polysaccharide hydrolase-invasin repeat family CF0475 39 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 89897950 Common efp2 elongation factor P CF0143 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 89898327 Common acpP acyl carrier protein CF0520 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 89898433 Pathogen - hypothetical protein CF0626 2 None None None 89898415 Common pp2C PP2C-like serine/threonine phosphatase CF0608 137 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 89898445 Common - hypothetical protein CF0638 4 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 89897925 Common ribD riboflavin biosynthesis protein CF0118 231 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 89898570 Common hrcA heat-inducible transcription repressor CF0763 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 89898015 Common plsX fatty acid/phospholipid synthesis protein CF0208 176 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 89897855 Pathogen - hypothetical protein CF0048 1 None None None 89898521 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B CF0714 210 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 89898069 Common map methionine aminopeptidase CF0262 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 89897822 Common folA dihydrofolate reductase CF0015 135 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 89898111 Common asd aspartate-semialdehyde dehydrogenase CF0304 193 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 89898650 Common swiB swiB complex protein CF0843 16 COG5531 COG5531, SWIB-domain-containing proteins implicated in chromatin remodeling Chromatin structure and dynamics 89898718 Common rplW 50S ribosomal protein L23 CF0911 42 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 89898389 Pathogen lam ATPase associated with chromosome architecture CF0582 2 None None None 89897896 Common secA preprotein translocase subunit SecA CF0089 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 89898594 Common ebp12 hypothetical protein CF0787 40 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 89898249 Pathogen lifA adherence factor CF0442 4 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 89897820 Common folB dihydroneopterin aldolase CF0013 4 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 89898140 Common valS valyl-tRNA synthetase CF0333 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898729 Common - hypothetical protein CF0922 166 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 89898004 Common rpsR 30S ribosomal protein S18 CF0197 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 89898403 Pathogen hctB histone H1-like protein Hc2 CF0595 1 None None None 89898536 Pathogen pmp11 polymorphic outer membrane protein pmp9 family CF0729 2 None None None 89898335 Pathogen - hypothetical protein CF0528 2 None None None 89897905 Common pckA phosphoenolpyruvate carboxykinase CF0098 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 89897944 Common hemN1 coproporphyrinogen III oxidase CF0137 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 89898501 Pathogen - hypothetical protein CF0694 1 None None None 89898158 Common prfA peptide chain release factor 1 CF0351 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 89898756 Pathogen - hypothetical protein CF0949 2 None None None 89897979 Pathogen - hypothetical protein CF0172 2 None None None 89898808 Common tyrB aromatic amino acid aminotransferase CF1001 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 89898762 Common - hypothetical protein CF0955 154 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 89898164 Common rnhB ribonuclease HII CF0357 218 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 89898455 Common gcsH glycine cleavage system protein H CF0648 184 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 89898516 Common rnhB2 ribonuclease HIII CF0709 33 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 89898181 Common gsa glutamate-1-semialdehyde aminotransferase CF0374 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 89898376 Common ytgB1 ABC transporter of metals CF0569 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 89898469 Common mrsA2 phosphoglucomutase/phosphomannomutase CF0662 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 89898348 Common nusA transcription elongation factor NusA CF0541 217 COG0195 NusA, Transcription elongation factor Transcription 89897827 Common pi4K phophatidylinositol-4-phosphate 5-kinase CF0020 18 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 89898745 Pathogen - hypothetical protein CF0938 1 None None None 89898691 Common lplA1 lipoate protein ligase A CF0884 46 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 89898605 Common dagA2 D-alanine/glycine permease CF0798 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 89898287 Common ycfV ABC transporter of lipoproteins CF0480 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 89897873 Common gspD general secretion pathway protein D CF0066 136 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 89898790 Common nab2 hypothetical protein CF0983 59 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 89898329 Common fabD malonyl acyl carrier transcyclase CF0522 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 89898027 Common mhcA3 myosin heavy chain-like protein CF0220 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898280 Pathogen - hypothetical protein CF0473 1 None None None 89898128 Common rpoC DNA-directed RNA polymerase subunit beta' CF0321 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 89898380 Common adt1 ADP/ATP translocase CF0573 15 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 89897955 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CF0148 226 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 89898562 Common - hypothetical protein CF0755 39 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 89898730 Pathogen ebp15 hypothetical protein CF0923 3 None None None 89897839 Common - hypothetical protein CF0032 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 89897852 Common sdhA succinate dehydrogenase flavoprotein subunit CF0045 223 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 89898661 Common - hypothetical protein CF0854 6 None None None 89897834 Common rpoN RNA polymerase factor sigma-54 CF0027 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 89898072 Common adk1 adenylate kinase CF0265 100 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 89897990 Common ebp03 hypothetical protein CF0183 7 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 89898481 Common ptsH phosphotransferase system histidine-containing protein HPr CF0674 72 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 89898244 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase CF0437 194 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 89898471 Common rnc ribonuclease III CF0664 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 89898560 Common ycfF bis (5'-nucleosyl)-tetraphosphatase CF0753 204 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 89898314 Common dppF2 ABC transporter of dipeptides CF0507 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 89898631 Common gltX glutamyl-tRNA synthetase CF0824 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 89898172 Common groEL chaperonin GroEL CF0365 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 89898659 Common atoC nitrogen regulation two-component transcription regulatory protein CF0852 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 89897997 Pathogen - hypothetical protein CF0190 1 None None None 89898711 Common rpsQ 30S ribosomal protein S17 CF0904 228 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 89898713 Common rplP 50S ribosomal protein L16 CF0906 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 89898372 Common yaeL membrane-associated Zn-dependent proteases CF0565 203 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 89897991 Common uvrC excinuclease ABC subunit C CF0184 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 89898142 Common uvrA excinuclease ABC subunit A CF0335 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 89898524 Pathogen - hypothetical protein CF0717 2 COG2155 COG2155, Uncharacterized conserved protein Function unknown 89898352 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase CF0545 210 COG0196 RibF, FAD synthase Coenzyme metabolism 89898538 Common pmp13 polymorphic outer membrane protein H family CF0731 11 None None None 89898565 Common - hypothetical protein CF0758 24 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 89898056 Pathogen - hypothetical protein CF0249 3 COG0795 COG0795, Predicted permeases General function prediction only 89898473 Common hemC porphobilinogen deaminase CF0666 221 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 89898591 Pathogen - hypothetical protein CF0784 1 None None None 89898602 Common - hypothetical protein CF0795 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 89897885 Pathogen - hypothetical protein CF0078 3 None None None 89898737 Common uhpC hexosphosphate transport CF0930 147 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 89898456 Pathogen - hypothetical protein CF0649 3 None None None 89897998 Common glyQ glycyl tRNA synthetase CF0191 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 89898502 Common tpiA triosephosphate isomerase CF0695 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 89898488 Pathogen rpsU 30S ribosomal protein S21 CF0681 3 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 89897824 Common pqqC coenzyme PQQ synthesis protein C CF0017 38 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 89898696 Pathogen ebp14 hypothetical protein CF0889 3 None None None 89898598 Common lpxK tetraacyldisaccharide 4'-kinase CF0791 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 89898020 Pathogen - hypothetical protein CF0213 1 None None None 89897835 Common uvrD DNA/RNA helicase CF0028 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 89898343 Common lgt prolipoprotein diacylglyceryl transferase CF0536 202 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 89898793 Pathogen - hypothetical protein CF0986 2 None None None 89898168 Common recD2 ATP-dependent dsDNA/ssDNA exodeoxyribonuclease V alpha CF0361 144 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 89898229 Pathogen - hypothetical protein CF0422 1 None None None 89898285 Pathogen - hypothetical protein CF0478 1 None None None 89898256 Pathogen - hypothetical protein CF0449 1 None None None 89898065 Pathogen - hypothetical protein CF0258 2 None None None 89898491 Common lon lon/ATP-dependent protease La CF0684 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 89897972 Common ppa inorganic pyrophosphatase CF0165 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 89898277 Pathogen - hypothetical protein CF0470 1 None None None 89898701 Common rpsM 30S ribosomal protein S13 CF0894 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 89897922 Common zntA cadmium/zinc cation transporting ATPase CF0115 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 89898215 Common kdtA2 3-deoxy-manno-octulosonate cytidylyltransferase CF0408 140 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 89897818 Pathogen - hypothetical protein CF0010 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898408 Pathogen - hypothetical protein CF0601 3 None None None 89898789 Common rsuD ribosomal large subunit pseudouridine synthase D CF0982 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 89898133 Pathogen - hypothetical protein CF0326 3 None None None 89897899 Common pcnB1 poly (A) polymerase CF0092 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 89898241 Common kynU kynureninase CF0434 126 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 89897907 Pathogen - hypothetical protein CF0100 2 None None None 89898330 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III CF0523 223 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 89897902 Common tig trigger factor CF0095 177 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 89898657 Common atoS nitrogen regulation two-component sensor histidine kinase ntrB CF0850 220 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 89898623 Common rps7 30S ribosomal protein S7 CF0816 216 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 89898342 Common imp1 putative inner membrane protein translocase component YidC CF0535 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 89898658 Common incA2 inclusion membrane protein CF0851 52 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898113 Common dapA dihydrodipicolinate synthase CF0306 232 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 89897843 Common ami2 N-acetylmuramoyl-L-alanine amidase CF0036 6 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 89898807 Common mreC cell division related rod shape-determining membrane protein CF1000 12 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 89898151 Pathogen - hypothetical protein CF0344 3 None None None 89898236 Common - hypothetical protein CF0429 64 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 89898050 Common infC translation initiation factor IF-3 CF0243 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 89898543 Common pmp17 polymorphic outer membrane protein E family CF0736 4 None None None 89897892 Common nth enodnuclease III CF0085 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 89897956 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase CF0149 207 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 89898337 Common pdhB pyruvate dehydrogenase E1 beta chain CF0530 191 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 89898754 Common dppF1 ABC transporter of dipeptides CF0947 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 89898318 Common mgtE Mg++ transporter CF0511 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 89898146 Common - hypothetical protein CF0339 5 None None None 89898746 Common rrm14 tRNA/rRNA methyltransferase CF0939 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 89897961 Common nab1 nucleic acid binding protein CF0154 61 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 89898630 Pathogen - hypothetical protein CF0823 2 None None None 89898081 Pathogen - hypothetical protein CF0274 2 None None None 89897927 Common ribH riboflavin synthase subunit beta CF0120 227 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 89898444 Pathogen ebp07 hypothetical protein CF0637 2 None None None 89897870 Common mutL DNA mismatch repair protein CF0063 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 89898067 Pathogen - hypothetical protein CF0260 3 None None None 89898382 Common lepA GTP-binding protein LepA CF0575 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 89897982 Common cysS cysteinyl-tRNA synthetase CF0175 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898557 Common panF sodium/proline, sodium/panthothenate symporters CF0750 62 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 89898437 Common himD DNA-binding protein HU CF0630 165 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 89898439 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CF0632 214 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 89898414 Common nifS2 cysteine desulfurase CF0607 225 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 89898369 Common dnaN DNA polymerase III subunit beta CF0562 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 89898096 Common aroDE bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase protein CF0289 213 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 89898419 Pathogen - hypothetical protein CF0612 1 None None None 89898036 Common sucC succinyl-CoA synthetase subunit beta CF0229 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 89897910 Common uap UDP-N-acetylglucosamine pyrophosphorylase CF0103 7 COG4284 COG4284, UDP-glucose pyrophosphorylase Carbohydrate transport and metabolism 89898328 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CF0521 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 89898240 Common kprS ribose-phosphate pyrophosphokinase CF0433 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 89897829 Pathogen - hypothetical protein CF0022 2 None None None 89897816 Common rpsT 30S ribosomal protein S20 CF0009 98 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 89898121 Pathogen secE preprotein translocase subunit SecE CF0314 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 89897969 Common ybeB chloroplast development gene iojAP superfamily CF0162 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 89898573 Common vacB ribonuclease R CF0766 192 COG0557 VacB, Exoribonuclease R Transcription 89898644 Pathogen ebp13 hypothetical protein CF0837 2 None None None 89898780 Pathogen ebp19 hypothetical protein CF0973 2 None None None 89898526 Common omp11 outer membrane protein CF0719 4 None None None 89898461 Pathogen - hypothetical protein CF0654 2 COG4129 COG4129, Predicted membrane protein Function unknown 89898324 Pathogen incC inclusion membrane protein CF0517 2 None None None 89898357 Pathogen sycE chaperone for secretion CF0550 3 None None None 89898587 Common dapF diaminopimelate epimerase CF0780 185 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 89898293 Common secA2 preprotein translocase secA subunit CF0486 17 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 89898458 Common lplA2 lipoate protein ligase A CF0651 26 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 89898198 Common leuS leucyl-tRNA synthetase CF0391 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898743 Pathogen - hypothetical protein CF0936 3 None None None 89897850 Common yabD deoxyribonuclease CF0043 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 89898771 Common karG ATP:guanido phosphotransferase CF0964 23 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 89898300 Pathogen - hypothetical protein CF0493 1 None None None 89898428 Common had hydrolase HAD superfamily CF0621 20 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 89897937 Common nqrF Na(+)-translocating NADH-quinone reductase subunit F CF0130 113 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 89898362 Pathogen - hypothetical protein CF0555 2 None None None 89898684 Common coaE dephospho-CoA kinase CF0877 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 89898190 Pathogen - hypothetical protein CF0383 1 None None None 89898106 Common fabG2 3-oxoacyl-[acyl-carrier-protein] reductase CF0299 218 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 89898079 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CF0272 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 89898518 Pathogen - hypothetical protein CF0711 2 None None None 89898395 Pathogen - hypothetical protein CF0588 3 None None None 89898083 Common lcrH2 type III secretion chaperone low calcium response protein H CF0276 8 None None None 89897821 Common folP folate synthesis bifunctional protein CF0014 220 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 89898209 Common oppB2 ABC transporter of peptides CF0402 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898612 Common adhS2 ABC transporter/periplasmic Mn/Zn-binding protein CF0805 149 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 89898596 Common sucB2 branched-chain alpha-keto acid dehydrogenase subunit E2 CF0789 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 89898626 Common tsp cell division related penicillin-binding proteinase CF0819 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 89897849 Common trxA1 thioredoxin CF0042 121 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 89897887 Common lipA lipoyl synthase CF0080 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 89897932 Common set SET domain protein CF0125 10 COG2940 COG2940, Proteins containing SET domain General function prediction only 89898765 Pathogen omp17 outer membrane protein OmpA CF0958 2 None None None 89898723 Common lpxA UDP-N-acetylglucosamine acyltransferase CF0916 171 COG1043 LpxA, Acyl- acyl carrier protein 89898178 Common rpiA ribose-5-phosphate isomerase A CF0371 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 89898260 Pathogen - hypothetical protein CF0453 1 None None None 89898120 Common tufA elongation factor Tu CF0313 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 89898673 Pathogen - hypothetical protein CF0866 1 None None None 89898582 Pathogen - hypothetical protein CF0775 2 None None None 89898040 Common ide3 insulinase family metalloproteinase CF0233 55 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 89898248 Pathogen - hypothetical protein CF0441 2 None None None 89898224 Pathogen - hypothetical protein CF0417 1 None None None 89898052 Common rplT 50S ribosomal protein L20 CF0245 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 89898703 Common rplO 50S ribosomal protein L15 CF0896 195 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 89898498 Pathogen - hypothetical protein CF0691 3 None None None 89898022 Pathogen - hypothetical protein CF0215 1 None None None 89898531 Pathogen pmp06 polymorphic outer membrane protein CF0724 2 None None None 89898424 Common rsuC ribosomal large subunit pseudouridine synthase C CF0617 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 89898049 Common nusB transcription antitermination protein NusB CF0242 32 COG0781 NusB, Transcription termination factor Transcription 89898639 Common cdsA phosphatidate cytidylyltransferase CF0832 82 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 89898279 Pathogen - hypothetical protein CF0472 1 None None None 89898715 Common rplV 50S ribosomal protein L22 CF0908 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 89898311 Pathogen - hypothetical protein CF0504 1 None None None 89897883 Common fliP type III secretion system protein CF0076 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 89898379 Pathogen - hypothetical protein CF0572 3 None None None 89898735 Common hisS histidyl-tRNA synthetase CF0928 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898354 Common yscU type III secretion system protein CF0547 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 89898153 Pathogen - hypothetical protein CF0346 2 None None None 89898144 Pathogen - hypothetical protein CF0337 1 None None None 89898741 Pathogen - hypothetical protein CF0934 3 None None None 89898567 Pathogen - hypothetical protein CF0760 1 None None None 89898704 Common rpsE 30S ribosomal protein S5 CF0897 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 89897837 Pathogen - hypothetical protein CF0030 2 None None None 89898019 Pathogen - hypothetical protein CF0212 1 None None None 89898486 Common pdhAB oxoisovalerate dehydrogenase alpha-beta fusion CF0679 184 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 89898504 Common xseB exodeoxyribonuclease VII small subunit CF0697 23 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 89897909 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase CF0102 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 89897946 Common mfd transcription-repair coupling factor-superfamily II helicase CF0139 225 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 89898031 Common mrsA1 phosphoglucomutase/phosphomannomutase CF0224 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 89897903 Common snf2 swi/snf family helicase 2 CF0096 161 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 89898752 Common ebp17 hypothetical protein CF0945 37 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 89898098 Common aroC chorismate synthase CF0291 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 89898062 Common - hypothetical protein CF0255 4 None None None 89898552 Pathogen - hypothetical protein CF0745 2 None None None 89897819 Common rpoD RNA polymerase sigma factor RpoD CF0012 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 89898513 Pathogen - hypothetical protein CF0706 1 None None None 89898655 Pathogen - hypothetical protein CF0848 2 None None None 89898339 Common glgP glycogen phosphorylase CF0532 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 89897868 Pathogen - hypothetical protein CF0061 2 None None None 89897954 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase CF0147 205 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 89898366 Common folD bifunctional protein CF0559 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 89897970 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II CF0163 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 89898238 Pathogen - hypothetical protein CF0431 1 None None None 89898674 Pathogen - hypothetical protein CF0867 2 None None None 89898800 Common nfo endonuclease IV CF0994 164 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 89898251 Pathogen - hypothetical protein CF0444 1 None None None 89897968 Common - hypothetical protein CF0161 5 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 89897989 Pathogen - hypothetical protein CF0182 2 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 89898254 Common trpB3 tryptophan synthase beta chain CF0447 17 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 89898213 Common - Holliday junction resolvase-like protein CF0406 108 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 89897977 Common bioF1 8-amino-7-oxononanoate synthase CF0170 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 89898002 Common pth peptidyl-tRNA hydrolase CF0195 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 89897863 Common parA chromosome partitioning ATPase CF0056 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 89898694 Common ruvC Holliday junction resolvase CF0887 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 89898511 Pathogen - hypothetical protein CF0704 1 None None None 89898663 Pathogen - hypothetical protein CF0856 2 None None None 89898010 Common ide2 insulinase family metalloproteinase CF0203 185 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 89898671 Common oppB1 ABC transporter of peptides CF0864 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898385 Pathogen - hypothetical protein CF0578 1 None None None 89898608 Common pmp19 polymorphic outer membrane protein A Family CF0801 8 None None None 89898046 Common trmB tRNA (guanine-N(7))-methyltransferase CF0239 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 89898412 Common tlyC1 hemolysin CF0605 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 89898475 Pathogen - hypothetical protein CF0668 1 None None None 89898667 Common pheT phenylalanyl-tRNA synthetase subunit beta CF0860 234 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 89898211 Common oppA5 ABC transporter/periplasmic oligopeptide binding lipoprotein component CF0404 172 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 89898283 Common rpsI 30S ribosomal protein S9 CF0476 219 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 89898550 Common hflX GTP-binding protein CF0743 217 COG2262 HflX, GTPases General function prediction only 89898410 Common dcd deoxycytidine triphosphate deaminase CF0603 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 89898541 Pathogen omp14 outer membrane protein CF0734 2 None None None 89898123 Common rplK 50S ribosomal protein L11 CF0316 245 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 89898298 Common ubiA prenyltransferase CF0491 123 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 89898585 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase CF0778 202 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 89898784 Common hemA glutamyl-tRNA reductase CF0977 171 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 89898033 Common tyrP tyrosine transport CF0226 38 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 89898355 Common lcrD type III secretory flagellar biosynthesis CF0548 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 89897877 Pathogen - hypothetical protein CF0070 2 None None None 89898463 Pathogen - hypothetical protein CF0656 2 None None None 89898218 Common tauB ABC transporter of Nitrate and Fe CF0411 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 89897980 Common dsbD1 thioredoxin/thiol-disulfide isomerase CF0173 5 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 89898767 Common tsf elongation factor Ts CF0960 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 89897929 Pathogen ebp02 hypothetical protein CF0122 3 None None None 89897959 Common murG N-acetylglucosaminyl transferase CF0152 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 89898760 Common sufC ABC transporter CF0953 247 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 89897847 Common exbD energy transducer CF0040 35 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 89897856 Common rsbU regulator of sigma subunit CF0049 3 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 89898430 Pathogen - hypothetical protein CF0623 3 COG5465 COG5465, Uncharacterized conserved protein Function unknown 89897993 Common dnaG DNA primase CF0186 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 89898442 Pathogen - hypothetical protein CF0635 3 None None None 89898620 Common cysJ sulfite reductase flavoprotein subunit CF0813 94 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 161611312 Common rpsJ 30S ribosomal protein S10 CF0814 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 89898034 Common yccA transport permease CF0227 97 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 89898393 Common sucB1 dihydrolipoamide acetyltransferase CF0586 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 89898085 Pathogen - hypothetical protein CF0278 1 None None None 89897912 Common fliI2 type III secretion system ATPase CF0105 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 89898091 Common dadA glycine dehyrogenase CF0284 20 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 89898360 Common oxr2 oxidoreductase CF0553 152 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 89898545 Pathogen - hypothetical protein CF0738 1 None None None 89898202 Common pfkA2 diphosphate--fructose-6-phosphate 1-phosphotransferase CF0395 94 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 89898332 Common omp06 outer membrane protein CF0525 151 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 89898642 Common argS arginyl-tRNA synthetase CF0835 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89897917 Common pgmA phosphoglyceromutase CF0110 154 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 89897936 Pathogen - hypothetical protein CF0129 2 None None None 89898610 Common thiM hydroxyethylthiazole kinase CF0803 78 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 89898787 Pathogen - hypothetical protein CF0980 2 None None None 89898528 Common pmp04 polymorphic outer membrane protein 9 CF0721 21 None None None 89897930 Common dagA1 D-alanine/glycine permease CF0123 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 89898584 Common - hypothetical protein CF0777 29 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 89897859 Common uvrB excinuclease ABC subunit B CF0052 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 89898029 Common pcnB2 Poly (A) polymerase CF0222 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 89897842 Pathogen - hypothetical protein CF0035 3 None None None 89898295 Common surE stationary phase survival protein SurE CF0488 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 89898117 Common - hypothetical protein CF0310 25 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 89898451 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D CF0644 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 89898725 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase CF0918 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 89898302 Common dpp zinc-dependent dipeptidase CF0495 76 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 89898426 Pathogen - hypothetical protein CF0619 2 None None None 89898227 Common - hypothetical protein CF0420 18 COG1738 COG1738, Uncharacterized conserved protein Function unknown 89898196 Common mhpA pentachlorophenol 4-monooxygenase CF0389 9 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 89898108 Common - hypothetical protein CF0301 70 COG1738 COG1738, Uncharacterized conserved protein Function unknown 89898506 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase CF0699 204 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 89898261 Common accC acetyl-CoA carboxylase biotin carboxylase subunit CF0454 222 COG0439 AccC, Biotin carboxylase Lipid metabolism 89898404 Common pepA leucyl aminopeptidase CF0597 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 89897994 Pathogen - hypothetical protein CF0187 2 None None None 89898226 Common tgt queuine tRNA-ribosyltransferase CF0419 228 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 89898682 Pathogen - hypothetical protein CF0875 2 None None None 89898670 Common oppC1 ABC transporter of peptides CF0863 212 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898252 Pathogen mac MAC/perforin family protein CF0445 2 None None None 89898609 Common pmp20 polymorphic outer membrane protein B CF0802 23 None None None 89897966 Common oxr4 hypothetical protein CF0159 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 89898059 Common pnp polynucleotide phosphorylase/polyadenylase CF0252 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 89898273 Common gcp2 O-sialoglycoprotein endopeptidase CF0466 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 89897975 Common sga sn-glycerol-3-p acyltransferase CF0168 11 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 89898768 Common pyrH uridylate kinase CF0961 239 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 89898646 Common - hypothetical protein CF0839 10 None None None 89897895 Common - hypothetical protein CF0088 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 89898101 Common ebp05 hypothetical protein CF0294 3 None None None 89898666 Pathogen lysM LysM motif repeat domain CF0859 3 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 89898157 Common rpmE2 50S ribosomal protein L31 type B CF0350 92 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 89898679 Common - hypothetical protein CF0872 16 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 89898007 Pathogen - hypothetical protein CF0200 1 None None None 89898161 Common rpsP 30S ribosomal protein S16 CF0354 200 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 89897951 Pathogen - hypothetical protein CF0144 2 None None None 89898527 Pathogen omp12 outer membrane protein CF0720 2 None None None 89897941 Pathogen - hypothetical protein CF0134 1 None None None 89898212 Common oppA4 ABC transporter/periplasmic oligopeptide binding lipoprotein component CF0405 145 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 89898204 Common - hypothetical protein CF0397 7 None None None 89898802 Common rpsD 30S ribosomal protein S4 CF0995 222 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 89898086 Common xerD site-specific tyrosine recombinase XerD CF0279 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 89898653 Common truA tRNA pseudouridine synthase A CF0846 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 89898726 Common lnt apolipoprotein N-acyltransferase CF0919 144 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 89897906 Pathogen - hypothetical protein CF0099 2 None None None 89898303 Common ywlC translation factor SUA5 family protein CF0496 230 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 89898045 Common nrdB ribonucleotide-diphosphate reductase subunit beta CF0238 161 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 89897848 Common tolQ biopolymer transport proteins CF0041 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 89898554 Pathogen - hypothetical protein CF0747 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 89898750 Common pgk phosphoglycerate kinase CF0943 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 89898313 Common app ABC transporter CF0506 101 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 89897874 Common gspE general secretion pathway protein E CF0067 210 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 89898125 Common rplJ 50S ribosomal protein L10 CF0318 126 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 89898346 Common trxB thioredoxin reductase CF0539 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 89898561 Common ebp09 hypothetical protein CF0754 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 89898459 Common clpB2 ATP-dependent Clp endopeptidase ATP-binding chain B CF0652 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 89898452 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E CF0645 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 89898616 Common rpmA 50S ribosomal protein L27 CF0809 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 89897831 Common oxr3 dehydrogenases CF0024 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 89898484 Pathogen - hypothetical protein CF0677 1 None None None 89898088 Pathogen ltuA late transcription unit A protein CF0281 2 None None None 89898717 Common rplB 50S ribosomal protein L2 CF0910 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 89897861 Pathogen ebp01 hypothetical protein CF0054 2 None None None 89897828 Pathogen - hypothetical protein CF0021 2 None None None 89898568 Pathogen - hypothetical protein CF0761 2 None None None 89898194 Common ligA NAD-dependent DNA ligase LigA CF0387 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 89898075 Common ychM sulfate transporter CF0268 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 89898692 Common ndk nucleoside diphosphate kinase CF0885 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 89898533 Pathogen pmp08 polymorphic outer membrane protein CF0726 3 None None None 89898377 Common - hypothetical protein CF0571 132 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 89898347 Common rpsA 30S ribosomal protein S1 CF0540 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 89898024 Common mhcB1 myosin heavy chain form B CF0217 134 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898136 Common atpD V-type ATP synthase subunit D CF0329 10 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 89898515 Common yfgA transcription regulator CF0708 35 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 89898464 Common ptsN1 phosphotransferase system mannitol/fructose-specific Pts IIA CF0657 108 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 89897948 Common tkt transketolase CF0141 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 89898734 Common aspS aspartyl-tRNA synthetase CF0927 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898637 Pathogen - hypothetical protein CF0830 1 None None None 89898520 Pathogen - hypothetical protein CF0713 2 COG0730 COG0730, Predicted permeases General function prediction only 89898267 Common rbn tRNA-processing ribonuclease BN CF0460 29 COG1295 Rbn, Predicted membrane protein Function unknown 89898482 Pathogen - hypothetical protein CF0676 3 None None None 89897926 Common ribA bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein CF0119 231 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 89898281 Common adk adenylate kinase CF0474 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 89898423 Common mutY adenine/guanine glycosylase CF0616 233 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 89898165 Common gmk guanylate kinase CF0358 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 89897845 Common tolB translocation protein TolB CF0038 144 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 89897889 Pathogen - hypothetical protein CF0082 2 None None None 89898625 Pathogen - hypothetical protein CF0818 2 None None None 89898321 Common aaaT proton:sodium-glutamate symport protein CF0514 151 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 89897854 Pathogen - hypothetical protein CF0047 3 None None None 89898264 Common rpe ribulose-phosphate 3-epimerase CF0457 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 89897913 Pathogen fliH type III secretory flagellar biosynthesis CF0106 2 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 89897933 Common phnP1 metal dependent hydrolase of the beta-lactamase superfamily I CF0126 57 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 89898138 Common atpK V-type ATP synthase subunit K CF0331 23 None None None 89898391 Common gcpE 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CF0584 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 89898315 Pathogen - hypothetical protein CF0508 2 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 89898500 Pathogen secG preprotein translocase subunit SecG CF0693 3 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 89898234 Common imdH inosine-5'-monophosphate dehydrogenase CF0427 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 89897882 Common fliQ type III secretion flagellar biosynthesis inner membrane protein CF0075 67 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 89898688 Common pgsA1 CDP-diacylglycerol/glycerol-3-P phosphatidyltransferase CF0881 116 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 89898290 Pathogen - hypothetical protein CF0483 2 None None None 89898230 Pathogen - hypothetical protein CF0423 1 None None None 89898148 Common cydA cytochrome D ubiquinol oxidase subunit I CF0341 162 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 89898387 Common flhA type III secretion system protein CF0580 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 89897866 Pathogen srpA2 wall surface anchor family protein CF0059 2 None None None 89898118 Pathogen - hypothetical protein CF0311 2 None None None 89898785 Common gyrB1 DNA topoisomerase IV subunit B CF0978 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 89898699 Common rpoA DNA-directed RNA polymerase subunit alpha CF0892 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 89898680 Common glgC glucose-1-phosphate adenylyltransferase CF0873 172 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 89898307 Common tdk thymidylate kinase CF0500 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 89898776 Common - hypothetical protein CF0969 17 None None None 89898154 Common ileS isoleucyl-tRNA synthetase CF0347 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89897987 Common rpmJ 50S ribosomal protein L36 CF0180 4 None None None 89898115 Pathogen - hypothetical protein CF0308 1 None None None 89898529 Common pmp05 polymorphic outer membrane protein CF0722 12 None None None 89898448 Pathogen - hypothetical protein CF0641 2 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 89897919 Pathogen - hypothetical protein CF0112 2 None None None 89898576 Pathogen - hypothetical protein CF0769 2 None None None 89898619 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CF0812 178 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 89898774 Common fliN type III secretion system protein CF0967 14 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 89897811 Common glmU UDP-GlcNAc pyrophosphorylase CF0004 114 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 89898477 Common imp2 inner membrane protein CF0670 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 89898578 Common - hypothetical protein CF0771 34 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 89898221 Common dsbG disulfide bond chaperone CF0414 20 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 89898434 Common msbA ABC transporter for multidrug CF0627 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 89898791 Pathogen - hypothetical protein CF0984 1 None None None 89898398 Pathogen awa1 cell wall associated hydrolases CF0591 2 None None None 89898706 Common rplF 50S ribosomal protein L6 CF0899 242 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 89898237 Pathogen - hypothetical protein CF0430 1 None None None 89897958 Common ftsW cell division related rod shape-determining membrane protein CF0151 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 89898522 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A CF0715 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 89898063 Pathogen - hypothetical protein CF0256 2 None None None 89898648 Common prfB peptide chain release factor 2 CF0842 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 89898547 Common glgB glycogen branching enzyme CF0740 150 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 89898317 Common xasA amino acid antiporter CF0510 113 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 89898093 Common ebp04 hypothetical protein CF0286 4 COG1945 COG1945, Uncharacterized conserved protein Function unknown 89898102 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase CF0295 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 89898188 Common - hypothetical protein CF0381 11 COG2912 COG2912, Uncharacterized conserved protein Function unknown 89898495 Common yjjK ABC transporter CF0688 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 89898409 Common ruvB Holliday junction DNA helicase B CF0602 213 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 89898466 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CF0659 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 89897826 Pathogen ygfA formyltetrahydrofolate cycloligase CF0019 2 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 89898008 Common - hypothetical protein CF0201 17 None None None 89898748 Pathogen - hypothetical protein CF0941 2 None None None 89898340 Pathogen - hypothetical protein CF0533 1 None None None 89898728 Common dnaQ2 DNA polymerase III subunit epsilon CF0921 190 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 89898016 Common pmp01 polymorphic outer membrane protein D CF0209 10 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 89898349 Common infB translation initiation factor IF-2 CF0542 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 89898607 Pathogen - hypothetical protein CF0800 2 None None None 89898005 Common rplI 50S ribosomal protein L9 CF0198 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 89898593 Pathogen - hypothetical protein CF0786 1 None None None 89897900 Common clpX ATP-dependent protease ATP-binding subunit CF0093 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 89898266 Common - hypothetical protein CF0459 16 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 89898651 Common pph1 phosphohydrolase CF0844 78 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 89898163 Common rplS 50S ribosomal protein L19 CF0356 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 89898489 Pathogen gcp1 o-sialoglycoprotein endopeptidase CF0682 3 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 89898804 Common recC ATP-dependent dsDNA/ssDNA exodeoxyribonuclease V gamma CF0998 72 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 89898374 Common ytgD ABC transporter of metals CF0567 50 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 89898645 Common - hypothetical protein CF0838 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 89897897 Pathogen - hypothetical protein CF0090 2 None None None 89898359 Common rpmB 50S ribosomal protein L28 CF0552 83 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 89898721 Pathogen - hypothetical protein CF0914 2 None None None 89898406 Pathogen - hypothetical protein CF0599 3 None None None 89897996 Pathogen - hypothetical protein CF0189 2 None None None 89898071 Common - multiple antibiotic resistance protein CF0264 34 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 89898334 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase CF0527 153 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 89898250 Pathogen pplD2 phospholipase D endonuclease CF0443 2 None None None 89898363 Pathogen - hypothetical protein CF0556 2 None None None 89898037 Common sucD succinyl-CoA synthetase subunit alpha CF0230 215 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 89898509 Common trxA2 thioredoxin CF0702 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 89898176 Pathogen - hypothetical protein CF0369 1 None None None 89897943 Common hemY protoporphyrinogen oxidase CF0136 38 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 89898809 Common greA transcript cleavage factor/unknown domain fusion protein CF1002 189 COG1747 COG1747, Uncharacterized N-terminal domain of the transcription elongation factor GreA Function unknown 89897973 Common gdhA glutamate/leucine dehydrogenase CF0166 110 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 89898757 Common xcd xylanase/chitin deacetilase CF0950 6 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 89898761 Common ynhE cysteine desulfurase activator complex subunit SufB CF0954 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 89897964 Common rsbV2 anti-sigma F factor antagonist CF0157 36 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 89898604 Common lspA lipoprotein signal peptidase CF0797 96 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 89898668 Common - hypothetical protein CF0861 6 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 89898690 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CF0883 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 89898732 Common rrm13 tRNA/rRNA methyltransferase CF0925 166 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 89898243 Common trpB1 tryptophan synthase subunit beta CF0436 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 89898275 Common zwf glucose-6-phosphate 1-dehydrogenase CF0468 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 89898798 Pathogen srpA1 wall surface anchor family protein CF0991 2 COG5064 SRP1, Karyopherin (importin) alpha Intracellular trafficking and secretion 89898026 Pathogen - hypothetical protein CF0219 1 None None None 89897890 Common snf1 swi/snf family helicase 2 CF0083 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 89898375 Common ytgC ABC transporter of metals CF0568 102 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 89898210 Common oppA2 ABC transporter/periplasmic oligopeptide binding lipoprotein component CF0403 170 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 89898635 Common secDF bifunctional preprotein translocase subunit SecD/SecF CF0828 210 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 89898627 Pathogen - hypothetical protein CF0820 1 None None None 89898493 Common atsA ribonuclease Z CF0686 94 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 89898632 Pathogen euo2 Hc protease EUO CF0825 3 None None None 89898479 Common ebp hypothetical protein CF0672 120 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 89898184 Pathogen - hypothetical protein CF0377 2 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 89898759 Common sufB ABC transporter integral membrane protein CF0952 176 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 89898171 Pathogen - hypothetical protein CF0364 2 None None None 89898563 Common - hypothetical protein CF0756 6 None None None 89898127 Common rpoB DNA-directed RNA polymerase subunit beta CF0320 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 89897833 Pathogen - hypothetical protein CF0026 3 None None None 89898535 Pathogen pmp10 polymorphic outer membrane protein CF0728 3 None None None 89898454 Pathogen - hypothetical protein CF0647 1 None None None 89898719 Common rplD 50S ribosomal protein L4 CF0912 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 89898350 Common rbfA ribosome-binding factor A CF0543 121 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 89898739 Pathogen - hypothetical protein CF0932 3 None None None 89898381 Pathogen - hypothetical protein CF0574 1 None None None 89898660 Pathogen - hypothetical protein CF0853 1 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 89898614 Common yebI ABC transporter of metals CF0807 150 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 89898192 Pathogen - hypothetical protein CF0385 1 None None None 89898336 Common pdhA pyruvate dehydrogenase E1 alpha chain CF0529 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 89898629 Pathogen omp16 outer membrane protein CF0822 2 None None None 89897939 Common rrm1 tRNA/rRNA methyltransferase CF0132 164 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 89898580 Common rsbV1 anti-sigma F factor antagonist CF0773 53 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 89898537 Common pmp12 polymorphic outer membrane protein G/9 family CF0730 30 None None None 89898159 Common rrm4 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase CF0352 222 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 89898038 Common htrA DO serine protease CF0231 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 89898206 Common oppF ABC transporter of peptides CF0399 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 89898061 Common yfhC cytosine/adenosine deaminases CF0254 212 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 89898139 Pathogen - hypothetical protein CF0332 3 None None None 89897879 Pathogen - hypothetical protein CF0072 2 None None None 89897985 Common rnpA ribonuclease P CF0178 26 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 89897872 Pathogen - hypothetical protein CF0065 3 None None None 89897920 Common birA biotin--protein ligase CF0113 108 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 89898421 Common - hypothetical protein CF0614 26 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 89897915 Common nifU NifU-related protein CF0108 11 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 89898480 Common ptsI phosphoenolpyruvate-protein phosphotransferase CF0673 228 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 89898676 Common hemH ferrochelatase CF0869 173 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 89898470 Pathogen - hypothetical protein CF0663 2 None None None 89898778 Pathogen - hypothetical protein CF0971 2 None None None 89897880 Pathogen - hypothetical protein CF0073 2 None None None 89898292 Pathogen - hypothetical protein CF0485 2 None None None 89898173 Common groES co-chaperonin GroES CF0366 213 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 89898077 Common nhaD sodium/proton antiporter CF0270 35 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 89898686 Common sppA periplasmic serine proteases IV CF0879 162 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 89898396 Common hemN2 coproporphyrinogen III oxidase CF0589 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 89898132 Common atpE V-type ATP synthase subunit E CF0325 8 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 89898364 Pathogen ltuB late transcription unit B protein CF0557 2 None None None 89898232 Pathogen - hypothetical protein CF0425 1 None None None 89898239 Pathogen - hypothetical protein CF0432 1 None None None 89898416 Pathogen - hypothetical protein CF0609 1 None None None 89898319 Pathogen - hypothetical protein CF0512 2 None None None 89897864 Common thrS threonyl-tRNA synthetase CF0057 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898601 Common ribC riboflavin synthase subunit alpha CF0794 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 89897962 Common cutA periplasmic divalent cation tolerance protein CutA1 CF0155 116 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 89898186 Pathogen pmp02 polymorphic outer membrane protein CF0379 2 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 89898590 Pathogen hemD uroporphyrinogen-III synthase CF0783 3 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 89898769 Common frr ribosome recycling factor CF0962 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 89898468 Common sodM Mn superoxide dismutase CF0661 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 89898763 Common ftsI1 cell division related penicillin-binding protein CF0956 181 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 89898781 Pathogen ebp20 hypothetical protein CF0974 3 None None None 89898104 Common bioF2 8-amino-7-oxononanoate synthase CF0297 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 89898326 Common cpkR cAMP-dependent protein kinase regulatory chain CF0519 48 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 89898042 Common pssA phosphatidylserine synthase CF0235 145 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 89898014 Common rpmF 50S ribosomal protein L32 CF0207 58 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 89898068 Pathogen mhcA2 myosin heavy chain CF0261 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 89898640 Common cmk cytidylate kinase CF0833 208 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 89897813 Pathogen - hypothetical protein CF0006 2 None None None 89898167 Common metG methionyl-tRNA synthetase CF0360 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 89898309 Common gyrB DNA gyrase subunit B CF0502 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 89898571 Common grpE heat shock protein HSP70 cofactor CF0764 232 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 89897830 Common ylmG integral membrane protein CF0023 42 COG0762 COG0762, Predicted integral membrane protein Function unknown 89898432 Common - hypothetical protein CF0625 35 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 89897809 Pathogen - hypothetical protein CF0002 3 None None None 89898446 Common dnaA chromosomal replication initiation protein CF0639 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 89898013 Pathogen - hypothetical protein CF0206 3 None None None 89898559 Pathogen - hypothetical protein CF0752 3 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion