Hahella chejuensis KCTC 2396, complete genome NC_007645 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 83645024 Common potD Spermidine/putrescine-binding periplasmic protein HCH_02206 143 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83645230 Common - protein containing tetratricopeptide repeats HCH_02433 43 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 83644327 Common - hypothetical protein HCH_01479 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 83648058 Common efp translation elongation factor P HCH_05399 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 83649681 Nonpathogen - hypothetical protein HCH_07079 1 None None None 83648491 Common - hypothetical protein HCH_05851 66 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 83643233 Common - Glutamate synthase domain 2 HCH_00332 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 83643188 Common rho transcription termination factor Rho HCH_00285 203 COG1158 Rho, Transcription termination factor Transcription 83649422 Common - Transcriptional regulator HCH_06808 168 COG0583 LysR, Transcriptional regulator Transcription 83646320 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03587 7 None None None 83646682 Common - N-acetylglucosamine-binding protein A HCH_03973 33 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 83643617 Common - NAD-dependent aldehyde dehydrogenase HCH_00729 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83645195 Common - Glycosyltransferase HCH_02393 23 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83648355 Common - hypothetical protein HCH_05709 4 None None None 83645267 Common - Threonine dehydrogenase and related Zn-dependent dehydrogenase HCH_02471 211 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 83647612 Common - Signal transduction histidine kinase HCH_04933 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83649351 Common - copper-translocating P-type ATPase HCH_06735 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 83648878 Nonpathogen - hypothetical protein HCH_06241 3 COG1416 COG1416, Uncharacterized conserved protein Function unknown 83645994 Nonpathogen - hypothetical protein HCH_03244 1 None None None 83647772 Common - Type III secretory pathway, component EscV HCH_05101 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 83646426 Common - Ca2+/Na+ antiporter HCH_03699 127 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 83645444 Nonpathogen - hypothetical protein HCH_02666 1 None None None 83645886 Nonpathogen - hypothetical protein HCH_03132 1 None None None 83643869 Nonpathogen - hypothetical protein HCH_00994 1 None None None 83643101 Common - predicted transcriptional regulator HCH_00194 94 COG2378 COG2378, Predicted transcriptional regulator Transcription 83649175 Common - hypothetical protein HCH_06546 4 None None None 83643177 Common - FOG: EAL domain HCH_00274 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83645001 Nonpathogen - hypothetical protein HCH_02183 2 None None None 83648183 Common - predicted epimerase PhzC/PhzF-like protein HCH_05531 106 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 83643186 Common ppx Exopolyphosphatase HCH_00283 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 83645346 Nonpathogen - hypothetical protein HCH_02556 1 None None None 83645879 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_03125 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83648722 Common - Signal transduction histidine kinase HCH_06084 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647646 Nonpathogen - hypothetical protein HCH_04966 2 None None None 83642960 Common coxA cytochrome-c oxidase, subunit I HCH_00048 174 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 83648180 Common - hypothetical protein HCH_05528 101 COG2135 COG2135, Uncharacterized conserved protein Function unknown 83644090 Common carB carbamoyl phosphate synthase large subunit HCH_01228 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 83643656 Common - FOG: CheY-like receiver HCH_00769 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83645012 Common - ADP-ribose pyrophosphatase HCH_02195 85 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83647207 Common - ABC-type branched-chain amino acid transport system, permease component HCH_04516 158 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83643921 Common - Glycosyltransferase HCH_01049 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83647847 Common fliO Flagellar biogenesis protein HCH_05179 14 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 83647084 Common - Transcriptional regulator HCH_04389 191 COG0583 LysR, Transcriptional regulator Transcription 83645329 Common - Sulfite reductase, beta subunit (hemoprotein) HCH_02538 171 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 83646053 Common - hypothetical protein HCH_03308 36 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 83647246 Common - Phage terminase-like protein, large subunit HCH_04556 47 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 83646443 Common - Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HCH_03717 138 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83646734 Common - predicted signal transduction protein HCH_04029 56 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83648378 Common - Subtilisin-like serine protease HCH_05735 107 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 83649183 Nonpathogen - hypothetical protein HCH_06555 1 None None None 83649193 Common - Isochorismate hydrolase HCH_06565 90 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 83648743 Common - Parvulin-like peptidyl-prolyl isomerase HCH_06105 152 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 83644282 Common - protein containing putative phospholipid-binding domain HCH_01431 6 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 83649270 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_06647 175 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83646149 Common - uncharacterized membrane protein HCH_03410 99 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 83643579 Nonpathogen - hypothetical protein HCH_00690 1 None None None 83647756 Common - ABC-type multidrug transport system, ATPase component HCH_05085 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83643224 Common - NADPH:quinone reductase and related Zn-dependent oxidoreductase HCH_00322 169 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83644585 Nonpathogen - hypothetical protein HCH_01750 1 None None None 83647250 Common - Plasmid stabilization system protein HCH_10015 31 COG3668 ParE, Plasmid stabilization system protein General function prediction only 83647637 Common - putative aminopeptidase 2 HCH_04958 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 83649073 Common - hypothetical protein HCH_06438 2 None None None 83648812 Nonpathogen - protein containing tetratricopeptide repeat HCH_06177 1 None None None 83643831 Common - 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) HCH_00953 73 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 83645437 Common - phosphoadenosine phosphosulfate reductase HCH_02658 163 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 83649385 Common - hypothetical protein HCH_06771 10 None None None 83644666 Common - protein containing fibronectin type III domains HCH_01837 23 None None None 83643716 Common - putative lipase HCH_00833 39 COG1647 COG1647, Esterase/lipase General function prediction only 83645008 Common - predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein HCH_02190 97 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 83645203 Common - Nucleoside-diphosphate-sugar epimerase HCH_02402 163 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83646810 Nonpathogen - hypothetical protein HCH_04110 1 None None None 83645608 Nonpathogen - hypothetical protein HCH_02840 1 None None None 83644787 Common - hypothetical protein HCH_01964 114 COG2606 EbsC, Uncharacterized conserved protein Function unknown 83648915 Common - hypothetical protein HCH_06278 19 None None None 83649396 Common - hypothetical protein HCH_06782 10 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 83645657 Common - Phage DNA packaging protein, Nu1 subunit of terminase HCH_02893 6 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 83649603 Nonpathogen - hypothetical protein HCH_06998 11 None None None 83644780 Nonpathogen - probable glycosyl hydrolase HCH_01957 2 None None None 83648296 Common - hypothetical protein HCH_05648 20 None None None 83643259 Nonpathogen - hypothetical protein HCH_00357 1 None None None 83646581 Nonpathogen - hypothetical protein HCH_03864 1 None None None 83647953 Nonpathogen - hypothetical protein HCH_05289 3 None None None 83648981 Common - predicted membrane protein HCH_06345 58 COG3174 COG3174, Predicted membrane protein Function unknown 83645531 Common - Transcriptional regulator HCH_02756 41 COG1309 AcrR, Transcriptional regulator Transcription 83648905 Common folB dihydroneopterin aldolase HCH_06268 116 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 83645538 Common sixA2 phosphohistidine phosphatase SixA HCH_02764 40 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 83649300 Common - hypothetical protein HCH_06680 34 None None None 83647750 Common - Methylase involved in ubiquinone/menaquinone biosynthesis HCH_05078 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83648515 Common - hypothetical protein HCH_05875 5 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 83646493 Common - Rhs family protein HCH_03771 49 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83643841 Common cobU Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase HCH_00963 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 83648670 Nonpathogen - Acyl carrier protein HCH_06030 2 None None None 83645237 Common dedD probable DedD protein HCH_02440 17 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 83643564 Common - Signal transduction histidine kinase HCH_00674 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83645052 Common - predicted glycosyltransferase HCH_02236 160 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 83644978 Common clpP1 ATP-dependent Clp protease, proteolytic subunit ClpP HCH_02158 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83647793 Nonpathogen - hypothetical protein HCH_05123 1 None None None 83643899 Common argB acetylglutamate kinase HCH_01027 225 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 83649499 Nonpathogen - hypothetical protein HCH_06891 1 None None None 83643308 Common - hypothetical protein HCH_00407 7 None None None 83646776 Nonpathogen - hypothetical protein HCH_04073 1 None None None 83644554 Common - dTDP-4-dehydrorhamnose reductase-like protein HCH_01716 162 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 83644570 Common hemK Methylase of polypeptide chain release factors HCH_01734 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 83646621 Nonpathogen - hypothetical protein HCH_03909 1 None None None 83648438 Common mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase HCH_05797 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 83645123 Common - ABC-type uncharacterized transport system, ATPase components HCH_02310 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 83649034 Common - Nitrogen regulatory protein PII HCH_06398 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 83644592 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_01757 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644189 Common - Transposase and inactivated derivatives HCH_01332 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644425 Nonpathogen - hypothetical protein HCH_01579 1 None None None 83645156 Common aat leucyl/phenylalanyl-tRNA--protein transferase HCH_02343 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 83645059 Common msrA Peptide methionine sulfoxide reductase HCH_02243 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 83647666 Common - Pterin-4a-carbinolamine dehydratase HCH_04986 104 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 83647411 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_04723 8 None None None 83648229 Common - hypothetical protein HCH_05580 24 COG3826 COG3826, Uncharacterized protein conserved in bacteria Function unknown 83646049 Nonpathogen - hypothetical protein HCH_03304 1 None None None 83647983 Common rpoN RNA polymerase factor sigma-54 HCH_05320 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 83648256 Nonpathogen - hypothetical protein HCH_05608 1 None None None 83645106 Nonpathogen - hypothetical protein HCH_02293 1 None None None 83647090 Nonpathogen - hypothetical protein HCH_04395 1 None None None 83645474 Common - 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase HCH_02697 128 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 83648603 Common radA DNA repair protein RadA HCH_05962 212 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 83645905 Nonpathogen - hypothetical protein HCH_03152 1 None None None 83643175 Nonpathogen - hypothetical protein HCH_00272 1 None None None 83647396 Nonpathogen - hypothetical protein HCH_04708 1 None None None 83643853 Nonpathogen - hypothetical protein HCH_00976 1 None None None 83647010 Nonpathogen - hypothetical protein HCH_04313 2 None None None 83643151 Common - hypothetical protein HCH_00246 11 COG2353 COG2353, Uncharacterized conserved protein Function unknown 83647782 Common yscR type III secretion system protein HCH_05111 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 83648133 Common - Membrane-fusion protein HCH_05480 128 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83645914 Nonpathogen - hypothetical protein HCH_03161 1 None None None 83646669 Common - protein containing SWIM zinc finger domain HCH_03960 13 None None None 83645037 Common - hypothetical protein HCH_02220 94 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 83648819 Nonpathogen - hypothetical protein HCH_06185 1 None None None 83643317 Common - TRAP-type mannitol/chloroaromatic compound transport system, large permease component HCH_00417 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 83643170 Common - hypothetical protein HCH_00267 16 COG5473 COG5473, Predicted integral membrane protein Function unknown 83649546 Common - FOG: GGDEF domain HCH_06939 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643297 Common - Mu-like prophage FluMu protein gp28 HCH_00396 25 COG5484 COG5484, Uncharacterized conserved protein Function unknown 83645398 Common - hypothetical protein HCH_02618 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 83645987 Common - Transcriptional regulator HCH_03237 191 COG0583 LysR, Transcriptional regulator Transcription 83643194 Common hemC porphobilinogen deaminase HCH_00291 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 83645666 Nonpathogen - hypothetical protein HCH_02902 1 None None None 83643934 Common ilvA threonine ammonia-lyase, biosynthetic HCH_01063 190 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 83645401 Common - predicted glutamine amidotransferase HCH_02621 73 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 83643864 Common - hypothetical protein HCH_00988 7 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 83643424 Common - predicted periplasmic/secreted protein HCH_00529 21 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 83644273 Common slpA FKBP-type peptidyl-prolyl cis-trans isomerases 2 HCH_01421 135 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 83648263 Nonpathogen - hypothetical protein HCH_05615 1 None None None 83643525 Nonpathogen - hypothetical protein HCH_00634 1 None None None 83648080 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05423 19 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643558 Nonpathogen - hypothetical protein HCH_00668 1 None None None 83643624 Nonpathogen - hypothetical protein HCH_00736 1 None None None 83644990 Common - protein of unknown function (DUF547) HCH_02172 24 None None None 83645678 Nonpathogen - hypothetical protein HCH_02914 1 None None None 83646982 Nonpathogen - hypothetical protein HCH_04284 1 None None None 83648988 Common - Tfp pilus assembly protein, pilus retraction ATPase PilT HCH_06352 212 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 83643543 Nonpathogen - hypothetical protein HCH_00652 1 None None None 83648942 Nonpathogen - hypothetical protein HCH_06305 2 None None None 83649312 Nonpathogen - Na+/proline symporter HCH_06692 7 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 83643775 Common - uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains HCH_00893 16 COG4248 COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains General function prediction only 83647111 Common - Cytochrome c, mono- and diheme variants HCH_04417 17 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 83649686 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_07084 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647766 Nonpathogen - hypothetical protein HCH_05095 1 None None None 83643585 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_00696 216 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83646652 Nonpathogen - hypothetical protein HCH_03941 1 None None None 83648895 Common - hypothetical protein HCH_06258 4 None None None 83649320 Common - Cysteine synthase HCH_06702 203 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83649609 Common - hypothetical protein HCH_07004 10 None None None 83649325 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, permease component HCH_06707 179 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 83649134 Common - putative GTPase (G3E family) HCH_06503 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 83643373 Nonpathogen - hypothetical protein HCH_00474 1 None None None 83648258 Nonpathogen - hypothetical protein HCH_05610 1 None None None 83644778 Common - Large extracellular alpha-helical protein HCH_01955 80 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 83647893 Common - Molybdopterin-guanine dinucleotide biosynthesis protein A HCH_05228 105 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 83647363 Common - hypothetical protein HCH_04674 6 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83642967 Common - Beta-lactamase class C and other penicillin binding protein HCH_00055 100 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 83645481 Common - hypothetical protein HCH_02705 106 COG2835 COG2835, Uncharacterized conserved protein Function unknown 83647625 Common - uncharacterized protein, possibly involved in aromatic compounds catabolism HCH_04946 27 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83644289 Common - hypothetical protein HCH_01438 2 None None None 83647999 Common gatA glutamyl-tRNA(Gln) amidotransferase, A subunit HCH_05337 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 83647615 Common - DNA-binding transcriptional repressor FabR HCH_04936 51 COG1309 AcrR, Transcriptional regulator Transcription 83648920 Common - protein of unknown function (DUF955) HCH_06282 16 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 83645316 Common - Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains) HCH_02524 145 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 83649492 Nonpathogen - hypothetical protein HCH_06885 1 None None None 83643414 Nonpathogen - hypothetical protein HCH_00519 1 None None None 83643216 Common - predicted hydrolase of the alpha/beta superfamily HCH_00314 12 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 83644315 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01467 16 None None None 83646254 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03519 28 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644633 Common era GTP-binding protein Era HCH_01801 240 COG1159 Era, GTPase General function prediction only 83643325 Common - Alkylated DNA repair protein HCH_00425 40 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 83649592 Common - Glutaminase HCH_06987 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 83649044 Common - Signal transduction histidine kinase HCH_06409 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647058 Common ccmH cytochrome C biogenesis protein, CcmH family HCH_04362 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 83648342 Nonpathogen - hypothetical protein HCH_05696 4 None None None 83649657 Common - hypothetical protein HCH_07055 7 None None None 83647706 Common - predicted flavoprotein HCH_05033 118 COG0431 COG0431, Predicted flavoprotein General function prediction only 83647597 Common - TolA family protein HCH_04916 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83648958 Common - Amino acid transporters HCH_06322 145 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 83645562 Nonpathogen - hypothetical protein HCH_02793 1 None None None 83648312 Common - hypothetical protein HCH_05665 19 None None None 83644083 Common - Fe2+/Zn2+ uptake regulation protein HCH_01221 192 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83644959 Nonpathogen - hypothetical protein HCH_02140 1 None None None 83648827 Common rpoA DNA-directed RNA polymerase subunit alpha HCH_06193 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 83649459 Nonpathogen - hypothetical protein HCH_06849 4 None None None 83644341 Nonpathogen - hypothetical protein HCH_01493 1 None None None 83644463 Nonpathogen - hypothetical protein HCH_01616 1 None None None 83645095 Common - predicted redox protein, regulator of disulfide bond formation HCH_02280 88 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83647459 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_04775 146 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 83647919 Common glnD PII uridylyl-transferase HCH_05255 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 83648025 Common - Flagellar hook protein FlgE HCH_05365 7 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 83646306 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03575 15 None None None 83647801 Common - Type II secretory pathway, component PulD HCH_05131 133 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 83647658 Common rpsA 30S ribosomal protein S1 HCH_04978 221 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 83648792 Common - hypothetical protein HCH_06156 11 None None None 83644950 Common - predicted metal-dependent phosphoesterases (PHP family) HCH_02131 130 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 83646818 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_04118 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643926 Common - Glycosyltransferase HCH_01055 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83643958 Common upp uracil phosphoribosyltransferase HCH_01088 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 83646164 Common - ATPase involved in chromosome partitioning HCH_03426 147 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83643910 Common pip proline iminopeptidase HCH_01038 106 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83646955 Common - hypothetical protein HCH_04258 9 None None None 83644345 Common - Membrane-bound serine protease (ClpP class) HCH_01497 68 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 83645432 Common - hypothetical protein HCH_02653 7 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 83644376 Common - hypothetical protein HCH_01528 201 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 83646276 Common - Transcriptional regulator HCH_03544 126 COG1609 PurR, Transcriptional regulators Transcription 83648858 Common rpoC DNA-directed RNA polymerase subunit beta' HCH_06223 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 83642959 Common coxB cytochrome-c oxidase, subunit II HCH_00047 153 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 83644448 Nonpathogen - hypothetical protein HCH_01601 1 None None None 83646698 Common - predicted transcriptional regulator HCH_03990 11 None None None 83644816 Nonpathogen - hypothetical protein HCH_01991 1 None None None 83647518 Common - Acetyltransferase (isoleucine patch superfamily) HCH_04834 99 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 83644093 Common ftsJ 23S rRNA methylase HCH_01231 140 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 83643940 Common - hypothetical protein HCH_01069 37 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 83647904 Common lpxA acyl-[acyl-carrier-protein]--UDP-N-acetylglucosam ine O-acyltransferase HCH_05239 169 COG1043 LpxA, Acyl- acyl carrier protein 83648777 Common - ATPase of the AAA+ class HCH_06139 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 83648012 Common - predicted metal-dependent hydrolase HCH_05350 189 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 83646794 Common - FOG: TPR repeat HCH_04092 65 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83649012 Common - S-adenosylhomocysteine hydrolase HCH_06377 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 83647746 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_05073 192 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83647962 Common - Acetyl-CoA acetyltransferase HCH_05299 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83648281 Nonpathogen - hypothetical protein HCH_05633 1 None None None 83645566 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_02798 74 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83648779 Common - hypothetical protein HCH_06141 9 None None None 83645833 Common - Transcriptional regulator HCH_03077 77 COG0583 LysR, Transcriptional regulator Transcription 83643358 Common - Methyl-accepting chemotaxis protein HCH_00458 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83644603 Common - putative Mg2+ and Co2+ transporter CorB HCH_01768 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 83646221 Common - Polyketide synthase modules and related protein HCH_03485 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83644826 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_02002 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83644715 Common rnfE SoxR-reducing system protein RsxE HCH_01888 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 83643284 Common - probable phage protein HCH_00383 8 None None None 83643055 Common - hypothetical protein HCH_00146 22 None None None 83649261 Common - Acyl-CoA dehydrogenase HCH_06638 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83645835 Common gpmB Fructose-2,6-bisphosphatase HCH_03079 11 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 83646949 Common - hypothetical protein HCH_04252 45 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 83644054 Common gloA1 Lactoylglutathione lyase HCH_01189 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83645893 Common - dehydrogenase HCH_03140 43 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83647017 Common - Transcriptional regulator HCH_04321 148 COG0583 LysR, Transcriptional regulator Transcription 83643763 Nonpathogen - hypothetical protein HCH_00881 1 None None None 83646397 Nonpathogen - hypothetical protein HCH_03667 5 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 83646159 Common - Glycosyltransferase HCH_03421 45 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83644203 Common - Integral membrane protein HCH_01348 8 COG5488 COG5488, Integral membrane protein Function unknown 83643951 Common - hypothetical protein HCH_01081 38 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 83643876 Common - hypothetical protein HCH_01001 4 None None None 83648666 Nonpathogen - hypothetical protein HCH_06025 1 None None None 83643722 Nonpathogen - hypothetical protein HCH_00839 1 None None None 83645554 Common - hypothetical protein HCH_02784 3 None None None 83648234 Common - hypothetical protein HCH_05585 5 None None None 83643050 Common thiE Thiamine monophosphate synthase HCH_00141 223 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 83649277 Nonpathogen - ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) HCH_06654 12 COG4360 APA2, ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) Nucleotide transport and metabolism 83645949 Common - Transcriptional regulator HCH_03198 93 COG1309 AcrR, Transcriptional regulator Transcription 83647275 Common - predicted exporters of the RND superfamily HCH_04584 65 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 83649203 Nonpathogen - hypothetical protein HCH_06576 2 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 83647838 Common - FOG: CheY-like receiver HCH_05170 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83643667 Common tesB acyl-CoA thioesterase II HCH_00781 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 83643660 Common - Kef-type K+ transport system, membrane components HCH_00774 202 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 83646627 Nonpathogen - hypothetical protein HCH_03915 1 None None None 83648018 Common - Rare lipoprotein B HCH_05356 32 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 83649452 Common - hypothetical protein HCH_06841 7 None None None 83645288 Common - Nitroreductase HCH_02494 94 COG0778 NfnB, Nitroreductase Energy production and conversion 83649342 Common - predicted transcriptional regulator HCH_06726 102 COG2378 COG2378, Predicted transcriptional regulator Transcription 83648384 Common - FOG: CheY-like receiver HCH_05741 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83646628 Nonpathogen - hypothetical protein HCH_03916 1 None None None 83649526 Common - predicted metal-dependent hydrolase with the TIM-barrel fold HCH_06919 113 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 83646198 Common - probable carbamoylphosphate synthase HCH_03461 75 COG0439 AccC, Biotin carboxylase Lipid metabolism 83646579 Common gcvH1 glycine cleavage system H protein HCH_03862 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 83647564 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04883 17 None None None 83647604 Nonpathogen - hypothetical protein HCH_04925 1 None None None 83643708 Common - predicted acetyltransferase and Hydrolase with the alpha/beta hydrolase fold HCH_00825 31 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 83643503 Nonpathogen - hypothetical protein HCH_00610 1 None None None 83645713 Nonpathogen - hypothetical protein HCH_02951 1 None None None 83643014 Common hypA hydrogenase formation/expression protein HypA HCH_00103 70 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 83648168 Common - Acyl-CoA hydrolase HCH_05516 133 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 83649165 Nonpathogen - hypothetical protein HCH_06536 1 None None None 83648361 Nonpathogen - hypothetical protein HCH_05717 1 None None None 83644920 Nonpathogen - hypothetical protein HCH_02101 1 None None None 83646526 Common - Superfamily II DNA/RNA helicase, SNF2 family HCH_03805 157 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83643919 Common rfaC lipopolysaccharide heptosyltransferase I HCH_01047 93 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 83646833 Common - Outer membrane protein HCH_04133 120 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83643388 Common - Glutathione peroxidase HCH_00491 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 83643803 Common atpD1 F0F1 ATP synthase subunit beta HCH_00923 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 83646657 Common - Isopropylmalate/homocitrate/citramalate synthases HCH_03947 194 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83644754 Common - Leucyl aminopeptidase HCH_01931 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 83643091 Common - uncharacterized iron-regulated protein HCH_00183 32 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 83643881 Common - predicted permease HCH_01006 104 COG0628 PerM, Predicted permease General function prediction only 83646892 Nonpathogen - hypothetical protein HCH_04195 1 None None None 83649624 Nonpathogen - hypothetical protein HCH_07019 1 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83645971 Nonpathogen - hypothetical protein HCH_03220 1 None None None 83647220 Common pdxH pyridoxamine 5'-phosphate oxidase HCH_04530 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 83643337 Common - Aspartate racemase HCH_00437 80 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 83643731 Common - predicted transcriptional regulator HCH_00848 130 COG1733 COG1733, Predicted transcriptional regulators Transcription 83646966 Common - Outer membrane receptor for ferrienterochelin and colicins HCH_04269 120 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 83646542 Common - enterobactin/ferric enterobactin esterase HCH_03821 35 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 83649519 Nonpathogen - hypothetical protein HCH_06911 1 None None None 83648327 Common - DNA modification methylase HCH_05682 114 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 83649581 Common - Biopolymer transport protein HCH_06976 14 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83648449 Common - ABC-type amino acid transport system, permease component HCH_05808 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83645776 Common - Membrane-fusion protein HCH_03019 164 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83647473 Common - hypothetical protein HCH_04789 38 COG3360 COG3360, Uncharacterized conserved protein Function unknown 83647072 Nonpathogen - hypothetical protein HCH_04377 1 None None None 83646876 Common - predicted Permease HCH_04179 17 COG0730 COG0730, Predicted permeases General function prediction only 83645416 Nonpathogen - hypothetical protein HCH_02636 1 None None None 83649088 Common - Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit HCH_06454 30 None None None 83647883 Common astE succinylglutamate desuccinylase HCH_05217 28 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 83643114 Common - hypothetical protein HCH_00208 45 COG3785 COG3785, Uncharacterized conserved protein Function unknown 83644365 Common prsA phosphoribosylpyrophosphate synthetase HCH_01517 230 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 83645452 Nonpathogen - hypothetical protein HCH_02674 2 None None None 83648428 Nonpathogen - hypothetical protein HCH_05787 1 None None None 83643753 Common - uncharacterized secreted protein HCH_00871 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 83647936 Common - Glycosyltransferase, probably involved in cell wall biogenesis HCH_05272 119 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83643406 Common - Protein-tyrosine-phosphatase HCH_00509 127 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83644514 Common - protein containing Immunoglobulin I-set domain and fibronectin type III domain HCH_01671 9 None None None 83646898 Nonpathogen - hypothetical protein HCH_04200 1 None None None 83649280 Nonpathogen - hypothetical protein HCH_06657 1 None None None 83644539 Common - Multiple antibiotic transporter HCH_01701 139 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 83646350 Common - predicted permease, DMT superfamily HCH_03620 126 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83646755 Nonpathogen - hypothetical protein HCH_04050 1 None None None 83648279 Common - DNA repair protein HCH_05631 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83642952 Common - hypothetical protein HCH_00040 6 None None None 83644494 Common - protein of unknown fuction HCH_01650 7 None None None 83645791 Common - Secreted trypsin-like serine protease HCH_03035 80 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 83648836 Common rplR 50S ribosomal protein L18 HCH_06200 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 83642923 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_00010 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 83649478 Nonpathogen - hypothetical protein HCH_06870 1 None None None 83649559 Nonpathogen - hypothetical protein HCH_06953 1 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 83646855 Common - hypothetical protein HCH_04156 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 83644850 Nonpathogen - hypothetical protein HCH_02026 1 None None None 83648404 Nonpathogen - hypothetical protein HCH_05763 1 None None None 83646113 Common - hypothetical protein HCH_03372 4 None None None 83648754 Common - Membrane-fusion protein HCH_06116 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83645965 Common - Multidrug resistance efflux pump HCH_03214 144 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83645134 Nonpathogen - hypothetical protein HCH_02321 1 None None None 83647541 Nonpathogen - hypothetical protein HCH_04859 1 None None None 83643493 Nonpathogen - hypothetical protein HCH_00600 2 None None None 83648198 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_05548 167 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83644156 Common - AraC-type DNA-binding domain-containing protein HCH_01299 148 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83643266 Nonpathogen - hypothetical protein HCH_00364 1 None None None 83647470 Nonpathogen - hypothetical protein HCH_04786 2 None None None 83644180 Common - hypothetical protein HCH_01322 13 None None None 83643508 Nonpathogen - hypothetical protein HCH_00616 2 None None None 83648820 Nonpathogen - hypothetical protein HCH_06186 1 None None None 83643678 Common - hypothetical protein HCH_00793 8 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 83646173 Common - probable sulfotransferase HCH_03435 12 None None None 83646063 Nonpathogen - hypothetical protein HCH_03318 1 None None None 83645730 Nonpathogen - hypothetical protein HCH_02970 1 None None None 83648684 Common - Microcystin-dependent protein HCH_06044 34 COG4675 MdpB, Microcystin-dependent protein Function unknown 83646390 Nonpathogen - hypothetical protein HCH_03660 1 None None None 83646854 Common - DNA-directed RNA polymerase specialized sigma subunit sigma24-like protein HCH_04155 145 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83646594 Nonpathogen - hypothetical protein HCH_03877 1 None None None 83647028 Common - hypothetical protein HCH_04332 67 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83647403 Nonpathogen - hypothetical protein HCH_04715 1 None None None 83648156 Nonpathogen - hypothetical protein HCH_05504 1 None None None 83648702 Common - hypothetical protein HCH_06063 12 None None None 83648808 Nonpathogen - hypothetical protein HCH_06173 1 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 83643464 Common - N6-adenine-specific methylase HCH_00571 207 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 83643289 Common - probable phage protein HCH_00388 11 None None None 83647269 Common rplT 50S ribosomal protein L20 HCH_04576 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 83648212 Common - Sterol desaturase HCH_05562 75 COG3000 ERG3, Sterol desaturase Lipid metabolism 83646910 Common - AraC-type DNA-binding domain-containing protein HCH_04213 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83643146 Common - hypothetical protein HCH_00241 17 None None None 83645519 Nonpathogen - hypothetical protein HCH_02744 1 None None None 83647578 Common galU UTP-glucose-1-phosphate uridylyltransferase HCH_04897 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 83643671 Common - hypothetical protein HCH_00785 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 83644873 Common - predicted signal transduction protein HCH_02052 57 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83647440 Nonpathogen - hypothetical protein HCH_04753 2 None None None 83643826 Common - hypothetical protein HCH_00948 48 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83646674 Nonpathogen - hypothetical protein HCH_03965 1 None None None 83645718 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02957 198 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648129 Common - Transposase and inactivated derivatives HCH_05476 33 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644296 Common adhC Zn-dependent alcohol dehydrogenase, class III HCH_01446 201 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 83647117 Common - predicted Fe-S oxidoreductase HCH_04423 165 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83644863 Common - hypothetical protein HCH_02039 6 None None None 83645525 Nonpathogen - hypothetical protein HCH_02750 2 None None None 83649128 Nonpathogen - hypothetical protein HCH_06497 2 None None None 83649433 Nonpathogen - hypothetical protein HCH_06820 1 None None None 83648351 Nonpathogen - hypothetical protein HCH_05706 3 None None None 83645323 Common - Cation/multidrug efflux pump HCH_02531 8 None None None 83648656 Common - GAF domain-containing protein HCH_06016 80 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 83643165 Common - uncharacterized membrane protein HCH_00262 43 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 83648797 Nonpathogen - Acyl carrier protein HCH_06161 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83648442 Common - predicted membrane protein HCH_05801 19 COG3556 COG3556, Predicted membrane protein Function unknown 83643442 Common gshB glutathione synthetase HCH_00547 122 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83646296 Nonpathogen - AraC-type DNA-binding domain-containing protein HCH_03565 1 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646013 Common - Flagellar motor switch/type III secretory pathway protein HCH_03264 23 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83648148 Nonpathogen - hypothetical protein HCH_05495 1 None None None 83644034 Common - ABC-type sugar transport system, ATPase component HCH_01167 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 83645739 Common - predicted signal transduction protein containing EAL and modified HD-GYP domains HCH_02980 67 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 83647803 Nonpathogen - hypothetical protein HCH_05132 1 None None None 83643202 Common xerC site-specific tyrosine recombinase XerC HCH_00300 222 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 83644929 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_02110 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645320 Common dnaQ DNA polymerase III, epsilon subunit HCH_02528 186 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83646514 Common - iron-enterobactin transporter membrane protein HCH_03792 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83643383 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_00485 42 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 83645864 Common - hypothetical protein HCH_03108 18 None None None 83645872 Nonpathogen - protein of unknown function (DUF0175) HCH_03117 1 COG2886 COG2886, Uncharacterized small protein Function unknown 83649129 Nonpathogen - hypothetical protein HCH_06498 3 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 83645584 Common - uncharacterized protein predicted to be involved in DNA repair HCH_02816 55 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83649584 Common - ABC-type sugar transport system, ATPase components HCH_06979 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83646199 Common - Methyl-accepting chemotaxis protein HCH_03462 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83644417 Nonpathogen - hypothetical protein HCH_01570 1 None None None 83646689 Nonpathogen - hypothetical protein HCH_03980 1 None None None 83648511 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_05871 161 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83648320 Common - hypothetical protein HCH_05675 11 None None None 83644009 Nonpathogen - hypothetical protein HCH_01142 1 None None None 83647872 Common csrA carbon storage regulator HCH_05205 62 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 83644174 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_01316 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83646570 Common - predicted phosphatase HCH_03852 98 COG0546 Gph, Predicted phosphatases General function prediction only 83647195 Common - ABC-type uncharacterized transport system, ATPase component HCH_04503 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 83643379 Common - Glycosidase HCH_00480 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83644136 Nonpathogen - hypothetical protein HCH_01278 1 None None None 83648329 Common - hypothetical protein HCH_10019 7 None None None 83645743 Common - predicted membrane protein HCH_02984 26 COG4539 COG4539, Predicted membrane protein Function unknown 83647657 Common ihfB integration host factor, beta subunit HCH_04977 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83648531 Common - hypothetical protein HCH_05892 131 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 83647392 Nonpathogen - hypothetical protein HCH_04704 1 None None None 83645590 Nonpathogen - hypothetical protein HCH_02822 1 None None None 83645190 Common - SAM-dependent methyltransferase HCH_02385 94 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83649157 Common - hypothetical protein HCH_06528 48 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 83648591 Nonpathogen - hypothetical protein HCH_05950 3 None None None 83646737 Common - Cation/multidrug efflux pump HCH_04032 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83647571 Common - Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II HCH_04890 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83642918 Common aarF ABC1 family protein kinase HCH_00005 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83646206 Common - predicted ATPase HCH_03469 54 COG4637 COG4637, Predicted ATPase General function prediction only 83643476 Nonpathogen - hypothetical protein HCH_00583 1 None None None 83647442 Common fadB multifunctional fatty acid oxidation complex subunit alpha HCH_04756 175 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 83648549 Nonpathogen - protein of unknown function (DUF1555) HCH_05909 7 None None None 83647035 Common - Sterol desaturase HCH_04339 77 COG3000 ERG3, Sterol desaturase Lipid metabolism 83649388 Common - hypothetical protein HCH_06774 5 None None None 83647521 Common - predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis HCH_04837 191 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 83647606 Common aspS aspartyl-tRNA synthetase HCH_04927 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83644559 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01721 39 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646414 Common sucB1 dihydrolipoamide acetyltransferase HCH_03685 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 83645368 Nonpathogen - hypothetical protein HCH_02585 1 None None None 83648882 Common argC N-acetyl-gamma-glutamyl-phosphate reductase HCH_06245 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 83645393 Common dnaX DNA polymerase III subunits gamma and tau HCH_02613 242 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 83642939 Common trkH Trk-type K+ transport system, membrane components HCH_00025 126 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 83645253 Common modE N-terminal domain of molybdenum-binding protein HCH_02455 118 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 83649549 Common - Membrane-fusion protein HCH_06942 167 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83644848 Nonpathogen - hypothetical protein HCH_02024 2 None None None 83647069 Common - DNA-binding ferritin-like protein HCH_04374 145 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 83642985 Common hypC hydrogenase assembly chaperone HypC/HupF HCH_00074 104 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83643693 Common - Signal transduction histidine kinase HCH_00809 223 COG3452 COG3452, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 83649401 Common - hypothetical protein HCH_06787 14 None None None 83644249 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase components HCH_01396 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83647243 Common - phage major capsid protein, HK97 family HCH_04553 54 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 83644627 Common mucC sigma factor algU negative regulatory protein MucC HCH_01793 15 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 83645588 Nonpathogen - hypothetical protein HCH_02820 2 None None None 83649575 Common - ABC-type sugar transport system, permease component HCH_06970 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83646361 Common bfr1 bacterioferritin HCH_03631 106 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 83646865 Common hutC histidine utilization repressor HCH_04168 128 COG2188 PhnF, Transcriptional regulators Transcription 83649564 Common trpB2 tryptophan synthase subunit beta HCH_06958 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 83643724 Common - hypothetical protein HCH_00842 4 None None None 83643973 Common - uncharacterized ABC-type transport system, permease component HCH_01103 118 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 83647977 Common - ABC-type transport system involved in resistance to organic solvents, ATPase component HCH_05314 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 83644569 Common prfA peptide chain release factor 1 HCH_01733 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 83643023 Nonpathogen - hypothetical protein HCH_00112 1 None None None 83649337 Nonpathogen - hypothetical protein HCH_06720 2 None None None 83644258 Common - predicted flavoprotein HCH_01405 102 COG0431 COG0431, Predicted flavoprotein General function prediction only 83646433 Common - Chemotaxis signal transduction protein HCH_03706 132 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83648990 Common proC pyrroline-5-carboxylate reductase HCH_06354 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 83643978 Common - predicted Fe-S-cluster oxidoreductase HCH_01110 25 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 83649007 Nonpathogen - hypothetical protein HCH_06372 2 None None None 83647879 Common - ABC-type histidine transport system, ATPase component HCH_05213 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 83649095 Common - Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase HCH_06461 98 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 83647165 Nonpathogen - hypothetical protein HCH_04471 1 None None None 83644436 Common coxS Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein HCH_01589 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 83646385 Nonpathogen - hypothetical protein HCH_03655 4 None None None 83645220 Common aroC chorismate synthase HCH_02421 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 83646635 Common - Signal transduction histidine kinase HCH_03924 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83649180 Common - predicted extracellular nuclease HCH_06552 51 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 83643595 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs HCH_00707 204 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83644678 Common - hypothetical protein HCH_01850 20 COG3868 COG3868, Uncharacterized conserved protein Function unknown 83648799 Common - Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II HCH_06164 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83647587 Common dapA2 dihydrodipicolinate synthase HCH_04906 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 83646512 Common - iron-enterobactin transporter periplasmic binding protein HCH_03790 56 COG4592 FepB, ABC-type Fe2+-enterobactin transport system, periplasmic component Inorganic ion transport and metabolism 83644021 Nonpathogen - hypothetical protein HCH_01154 1 None None None 83645733 Nonpathogen - hypothetical protein HCH_02974 1 None None None 83644080 Common - Oligoketide cyclase/lipid transport protein HCH_01217 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 83644936 Common - hypothetical protein HCH_02117 30 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 83645870 Common - ABC-type sugar transport system, periplasmic component HCH_03115 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83647079 Common - predicted phosphohydrolase HCH_04384 58 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83644605 Common ffh signal recognition particle protein HCH_01771 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 83645640 Common - hypothetical protein HCH_02874 3 None None None 83646973 Common - acyl CoA:acetate/3-ketoacid CoA transferase HCH_04276 101 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 83642973 Common - predicted deacylase HCH_00061 23 COG3608 COG3608, Predicted deacylase General function prediction only 83646554 Common - hypothetical protein HCH_03836 9 None None None 83643207 Common - Signal transduction histidine kinase HCH_00305 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83649415 Common - Transcriptional regulator HCH_06801 123 COG1846 MarR, Transcriptional regulators Transcription 83644455 Common potG ABC-type spermidine/putrescine transport system, ATPase components HCH_01608 243 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 83648522 Common murG undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase HCH_05883 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 83648844 Common rpmC ribosomal protein L29 HCH_06209 157 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 83647006 Common - Glycosidase HCH_04309 19 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83644407 Common - predicted chitinase HCH_01560 34 COG3179 COG3179, Predicted chitinase General function prediction only 83646963 Common - FOG: CheY-like receiver HCH_04265 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83646349 Common - Transcriptional regulator HCH_03619 91 COG0583 LysR, Transcriptional regulator Transcription 83649109 Common cobJ Precorrin-3B methylase HCH_06478 117 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 83648973 Nonpathogen - hypothetical protein HCH_06337 3 None None None 83649150 Nonpathogen - hypothetical protein HCH_06520 1 None None None 83649102 Common cbiD cobalt-precorrin-6A synthase HCH_06469 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 83647300 Common - Zn-dependent protease with chaperone function HCH_04609 180 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 83646748 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase HCH_04043 201 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 83643292 Common - hypothetical protein HCH_00391 10 None None None 83646887 Nonpathogen - hypothetical protein HCH_04190 3 None None None 83644756 Common - predicted Permease HCH_01933 85 COG0795 COG0795, Predicted permeases General function prediction only 83648860 Common rplL ribosomal protein L7/L12 HCH_06225 213 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 83649241 Common - FOG: TPR repeat HCH_06617 18 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83644622 Common - hypothetical protein HCH_01788 47 COG2938 COG2938, Uncharacterized conserved protein Function unknown 83648745 Common - predicted esterase of the alpha-beta hydrolase superfamily HCH_06107 76 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83648421 Common - Pseudouridylate synthases, 23S RNA-specific HCH_05780 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83645750 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_02991 93 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83643912 Nonpathogen - hypothetical protein HCH_01040 1 None None None 83649467 Common ilvM Acetolactate synthase (isozyme II), small (regulatory) subunit HCH_06859 8 COG3978 COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit Function unknown 83644522 Common - L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase HCH_01681 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 83647053 Common ubiG1 3-demethylubiquinone-9 3-methyltransferase HCH_04357 158 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83648894 Common - glutamyl-tRNA synthetase-related protein HCH_06257 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83649021 Nonpathogen - hypothetical protein HCH_06386 1 None None None 83644883 Nonpathogen - hypothetical protein HCH_02062 2 None None None 83643399 Common - protein of unknown function (DUF1555) HCH_00502 3 None None None 83646132 Common - probable oxidoreductase containing common central domain of tyrosinase HCH_03392 15 None None None 83648508 Common - Molybdenum cofactor biosynthesis enzyme HCH_05868 204 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83644527 Common - Acyl-CoA dehydrogenase HCH_01686 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83645499 Common - Glycosyltransferase HCH_02724 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83645681 Nonpathogen - hypothetical protein HCH_02917 1 None None None 83645214 Common pilZ Tfp pilus assembly protein PilZ HCH_02415 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 83646760 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_04055 121 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83644726 Common - Ribulose-5-phosphate 4-epimerase and related epimerase and aldolases HCH_01901 8 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 83647859 Common fliH2 putative flagellar assembly protein HCH_05191 56 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83648074 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components HCH_05415 12 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 83647262 Common - Transposase and inactivated derivatives HCH_04569 6 None None None 83646449 Common - hypothetical protein HCH_03724 2 None None None 83643344 Common - RNA-binding protein (RRM domain) HCH_00444 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 83644657 Common - hypothetical protein HCH_01828 57 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 83648641 Common - FOG: EAL domain HCH_06001 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83646993 Common - Serine/threonine protein phosphatase HCH_04296 135 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83648917 Nonpathogen - hypothetical protein HCH_06280 1 None None None 83643513 Nonpathogen - hypothetical protein HCH_00621 1 None None None 83645062 Nonpathogen - hypothetical protein HCH_02246 2 None None None 83649641 Common - Type I restriction-modification system methyltransferase subunit HCH_07036 9 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 83645500 Common - predicted ATP-grasp enzyme HCH_02725 47 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 83644957 Common - Periplasmic serine protease (ClpP class) HCH_02138 156 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83645483 Common - Protein-tyrosine-phosphatase HCH_02707 124 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83648476 Common lipA lipoyl synthase HCH_05836 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 83643078 Common - Na+/alanine symporter HCH_00169 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 83643071 Common - Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) HCH_00162 88 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 83644828 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_02004 57 COG2962 RarD, Predicted permeases General function prediction only 83646232 Nonpathogen - hypothetical protein HCH_03496 1 None None None 83648751 Common gph phosphoglycolate phosphatase, bacterial HCH_06113 204 COG0546 Gph, Predicted phosphatases General function prediction only 83647273 Common - ATPase involved in chromosome partitioning HCH_04582 203 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83644724 Common - ATPase involved in chromosome partitioning HCH_01899 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83648810 Nonpathogen - OEP (Outer membrane Efflux Protein) family protein HCH_06175 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83646706 Common - Nitrate/nitrite transporter HCH_03999 82 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 83646181 Common - Non-ribosomal peptide synthetase modules and related protein HCH_03444 215 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648049 Common - iron-sulfur cluster binding protein, putative HCH_05391 135 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 83644213 Common - predicted rRNA methylase (SpoU class) HCH_01358 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 83647374 Common - exopolysaccharide production protein HCH_04685 25 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 83644841 Nonpathogen - hypothetical protein HCH_02017 2 None None None 83646805 Nonpathogen - hypothetical protein HCH_04104 1 None None None 83648879 Common - hypothetical protein HCH_06242 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 83648486 Common nadD nicotinate (nicotinamide) nucleotide adenylyltransferase HCH_05846 179 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 83643750 Nonpathogen - hypothetical protein HCH_00868 1 None None None 83649267 Common - predicted Permease HCH_06644 89 COG0679 COG0679, Predicted permeases General function prediction only 83644739 Common ligT 2'-5' RNA ligase HCH_01914 62 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 83646524 Nonpathogen - hypothetical protein HCH_03802 2 None None None 83647980 Common - hypothetical protein HCH_05317 16 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 83644079 Common - Na+-dependent transporters of the SNF family HCH_01216 87 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 83644919 Common - protein containing transposase DDE domain HCH_02100 20 None None None 83649390 Nonpathogen - hypothetical protein HCH_06776 1 None None None 83644487 Common - Choline dehydrogenase and related flavoprotein HCH_01642 36 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 83644013 Common - putative NADPH-quinone reductase (modulator of drug activity B) HCH_01146 66 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 83645177 Nonpathogen - hypothetical protein HCH_02369 1 None None None 83645936 Common - Threonine dehydratase HCH_03183 182 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 83643229 Common - predicted aminopeptidase HCH_00327 28 COG2234 Iap, Predicted aminopeptidases General function prediction only 83645227 Common leuD isopropylmalate isomerase small subunit HCH_02429 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 83647328 Nonpathogen - hypothetical protein HCH_04639 1 None None None 83647344 Nonpathogen - hypothetical protein HCH_04655 1 None None None 83645825 Nonpathogen - hypothetical protein HCH_03069 1 None None None 83648016 Nonpathogen - hypothetical protein HCH_05354 1 None None None 83645286 Common - hypothetical protein HCH_02492 27 None None None 83647461 Common - NAD-specific glutamate dehydrogenase HCH_04777 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 83646471 Common - Methyl-accepting chemotaxis protein HCH_03747 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648452 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_05811 33 COG0456 RimI, Acetyltransferases General function prediction only 83647186 Common - HD-GYP domain HCH_04493 114 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 83644304 Nonpathogen - hypothetical protein HCH_01454 1 None None None 83645184 Nonpathogen - hypothetical protein HCH_02376 1 None None None 83648142 Common argF2 ornithine carbamoyltransferase HCH_05489 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 83649359 Common - Permease of the major facilitator superfamily HCH_06744 166 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83644697 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase HCH_01869 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 83644995 Common - NAD-dependent aldehyde dehydrogenase HCH_02177 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83648769 Nonpathogen - hypothetical protein HCH_06130 1 None None None 83645494 Nonpathogen - hypothetical protein HCH_02718 2 None None None 83646405 Nonpathogen - hypothetical protein HCH_03677 1 None None None 83649039 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase HCH_06403 83 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 83646923 Nonpathogen - hypothetical protein HCH_04226 2 None None None 83646843 Nonpathogen - hypothetical protein HCH_04143 1 None None None 83647500 Common - Deacetylases, including yeast histone deacetylase and acetoin utilization protein HCH_04816 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 83644765 Common - Zn-dependent dipeptidase HCH_01942 97 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 83644617 Common lysS lysyl-tRNA synthetase HCH_01783 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 83648082 Common - hypothetical protein HCH_05425 11 None None None 83649599 Common - predicted ATPase/kinase involved in NAD metabolism HCH_06994 34 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 83648692 Nonpathogen - hypothetical protein HCH_06051 1 None None None 83647865 Common - group II intron-encoding maturase HCH_05198 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83647154 Common ndk Nucleoside diphosphate kinase HCH_04460 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 83645161 Common - hypothetical protein HCH_02348 7 None None None 83646228 Nonpathogen - hypothetical protein HCH_03492 1 None None None 83644217 Common proX glycine betaine transporter periplasmic subunit HCH_01363 35 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 83644509 Nonpathogen - hypothetical protein HCH_01666 1 None None None 83643361 Common - Methylase of chemotaxis methyl-accepting protein HCH_00461 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83646568 Common - Methylase of chemotaxis methyl-accepting protein HCH_03850 142 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83644228 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01375 34 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644020 Nonpathogen - hypothetical protein HCH_01153 5 None None None 83646462 Nonpathogen - hypothetical protein HCH_03738 1 None None None 83645143 Common - hypothetical protein HCH_02330 65 COG2850 COG2850, Uncharacterized conserved protein Function unknown 83648648 Common - hypothetical protein HCH_06008 19 None None None 83646039 Common - Transposase and inactivated derivatives HCH_03294 51 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83645780 Common - Cytochrome c, mono- and diheme variants HCH_03024 21 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 83645244 Common - recombination factor protein RarA HCH_02447 245 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 83643028 Common - predicted kinase HCH_00117 55 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 83643980 Nonpathogen - hypothetical protein HCH_01112 1 None None None 83647021 Common - Methyl-accepting chemotaxis protein HCH_04325 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83646452 Nonpathogen - hypothetical protein HCH_03727 2 None None None 83643747 Common - hypothetical protein HCH_00865 10 None None None 83648332 Common - hypothetical protein HCH_05686 7 None None None 83646387 Nonpathogen - hypothetical protein HCH_03657 1 None None None 83647720 Common - Enoyl-CoA hydratase/carnithine racemase HCH_05047 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83646420 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_03692 148 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83647923 Common - Tetrahydrodipicolinate N-succinyltransferase HCH_05259 44 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 83648091 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_05434 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83645370 Common - Methyl-accepting chemotaxis protein HCH_02587 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643783 Common - ABC-type sugar transport system, periplasmic component HCH_00902 9 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83647297 Common - Superoxide dismutase HCH_04606 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 83649569 Common glpD glycerol-3-phosphate dehydrogenase HCH_06964 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83645726 Common - Polyketide synthase modules and related protein HCH_02965 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83646123 Nonpathogen - hypothetical protein HCH_03383 3 None None None 161897893 Common leuA1 2-isopropylmalate synthase HCH_05146 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83648963 Nonpathogen - hypothetical protein HCH_06327 4 None None None 83648095 Common - predicted small integral membrane protein HCH_05440 20 COG5472 COG5472, Predicted small integral membrane protein Function unknown 83645789 Common - hypothetical protein HCH_03033 38 COG3391 COG3391, Uncharacterized conserved protein Function unknown 83645806 Nonpathogen - hypothetical protein HCH_03050 1 None None None 83649207 Nonpathogen - hypothetical protein HCH_06580 1 None None None 83649032 Common - predicted ATPase with chaperone activity HCH_06394 190 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 83643108 Common - ABC-type sugar transport system, periplasmic component HCH_00201 102 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83648044 Common mutL DNA mismatch repair protein HCH_05385 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 83647465 Common - uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) HCH_04781 112 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 83647989 Common - hypothetical protein HCH_05327 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 83646561 Nonpathogen - hypothetical protein HCH_03843 1 None None None 83649144 Common - Transcriptional regulator HCH_06514 166 COG0583 LysR, Transcriptional regulator Transcription 83643571 Common - hypothetical protein HCH_00681 11 COG3179 COG3179, Predicted chitinase General function prediction only 83643608 Nonpathogen - hypothetical protein HCH_00720 1 None None None 83643806 Common - hypothetical protein HCH_00926 14 None None None 83644232 Nonpathogen - hypothetical protein HCH_01379 1 None None None 83649362 Nonpathogen - hypothetical protein HCH_06747 1 None None None 83646588 Common - AraC-type DNA-binding domain-containing protein HCH_03871 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83643006 Nonpathogen - hypothetical protein HCH_00095 1 None None None 83645363 Common - Transposase and inactivated derivatives HCH_02573 96 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644041 Common - Transcriptional regulator HCH_01175 184 COG0583 LysR, Transcriptional regulator Transcription 83645030 Common - Collagenase and related protease HCH_02212 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 83646001 Nonpathogen - hypothetical protein HCH_03252 1 None None None 83649659 Nonpathogen - hypothetical protein HCH_07057 1 None None None 83648542 Common rplM 50S ribosomal protein L13 HCH_05902 223 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 83644445 Common - hypothetical protein HCH_01598 7 COG4727 COG4727, Uncharacterized protein conserved in bacteria Function unknown 83645071 Nonpathogen - hypothetical protein HCH_02256 1 None None None 83648672 Common - Non-ribosomal peptide synthetase modules and related protein HCH_06032 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83644550 Common rpsR ribosomal protein S18 HCH_01712 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 83646886 Common - uncharacterized protein with a C-terminal OMP (outer membrane protein) domain HCH_04189 49 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 83649067 Common - TRAP-type C4-dicarboxylate transport system, large permease component HCH_06432 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 83648204 Nonpathogen - hypothetical protein HCH_05554 2 None None None 83648317 Common - Bacteriophage tail assembly protein HCH_05672 37 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 83645744 Common - Beta-glucanase/Beta-glucan synthetase HCH_02985 68 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 83646662 Common - dehydrogenase HCH_03954 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83644671 Common - hypothetical protein HCH_01843 10 None None None 83647101 Common - hypothetical protein HCH_04406 32 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 83647181 Common - Permease of the major facilitator superfamily HCH_04488 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83644965 Common acpP acyl carrier protein HCH_02145 180 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83648007 Common - Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase HCH_05345 157 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 83649494 Common - NAD-dependent protein deacetylases, SIR2 family HCH_06886 148 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 83643124 Common - CBS-domain-containing membrane protein HCH_00219 120 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 83645351 Common - Outer membrane receptor for ferrienterochelin and colicins HCH_02561 123 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 83646335 Nonpathogen - hypothetical protein HCH_03605 1 None None None 83648053 Common - Flagellar motor component HCH_05394 120 COG1291 MotA, Flagellar motor component Cell motility and secretion 83644476 Common - Serine/threonine protein kinase HCH_01630 173 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83646212 Nonpathogen - protein containing FG-GAP repeats HCH_03476 10 None None None 83644279 Nonpathogen - hypothetical protein HCH_01428 1 None None None 83644643 Common - Adenylate kinase and related kinase HCH_01814 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 83646904 Nonpathogen - hypothetical protein HCH_04207 2 None None None 83648398 Nonpathogen - hypothetical protein HCH_05757 1 None None None 83644656 Nonpathogen - protein containing immunoglobulin I-set domain HCH_01827 4 None None None 83644650 Common - hypothetical protein HCH_01821 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 83647430 Common lpdA2 dihydrolipoamide dehydrogenase HCH_04743 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83646109 Common napC Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit HCH_03367 47 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 83649540 Common - Tfp pilus assembly protein, major pilin PilA HCH_06933 83 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 83644069 Common - ABC-type multidrug transport system, ATPase and permease components HCH_01206 11 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 83649000 Common trmB tRNA (guanine-N(7)-)-methyltransferase HCH_06365 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 83644395 Common - hypothetical protein HCH_01548 12 None None None 83647710 Common - Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein HCH_05037 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 83649216 Common - Cation/multidrug efflux pump HCH_06591 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83648783 Common - Type II secretory pathway, pseudopilin PulG HCH_06146 38 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 83646767 Common - Rhs family protein HCH_04062 62 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83648105 Nonpathogen - hypothetical protein HCH_05450 1 None None None 83649486 Nonpathogen - hypothetical protein HCH_06878 1 None None None 83649513 Common - Transcriptional regulator HCH_06905 129 COG1609 PurR, Transcriptional regulators Transcription 83644048 Common - Transposase and inactivated derivatives HCH_01182 33 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643303 Nonpathogen - hypothetical protein HCH_00402 1 None None None 83645701 Common - ABC-type Mn2+/Zn2+ transport system, permease components HCH_02939 188 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83648038 Common - hypothetical protein HCH_05379 23 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 83645341 Nonpathogen - hypothetical protein HCH_02550 1 None None None 83644549 Common rpsF ribosomal protein S6 HCH_01711 182 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 83643061 Common - dihydrolipoamide dehydrogenase HCH_00152 234 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83647172 Common flgF flagellar basal body rod protein FlgF HCH_04478 124 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 83647934 Common - hypothetical protein HCH_05270 5 None None None 83649673 Common atpD2 F0F1 ATP synthase subunit beta HCH_07071 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 83648307 Common - hypothetical protein HCH_05660 5 None None None 83645468 Common nqrF Na(+)-translocating NADH-quinone reductase subunit F HCH_02691 159 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 83648571 Common fimT Tfp pilus assembly protein FimT HCH_10023 39 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 83643495 Common - Transposase and inactivated derivatives HCH_00601 33 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644572 Common phrB2 Deoxyribodipyrimidine photolyase HCH_01735 140 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 83648430 Common - Acyl-CoA dehydrogenase HCH_05789 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83647868 Common - Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit HCH_05201 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 83648336 Common - hypothetical protein HCH_05690 8 None None None 83644062 Common - Rhs family protein HCH_01199 61 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83645635 Nonpathogen - hypothetical protein HCH_02869 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83645688 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02925 72 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644194 Nonpathogen - hypothetical protein HCH_01337 1 None None None 83643248 Common - DNA-binding transcriptional regulator HexR HCH_00346 104 COG1737 RpiR, Transcriptional regulators Transcription 83645115 Common - Conserved domain frequently associated with peptide methionine sulfoxide reductase HCH_02302 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 83648903 Common pgi glucose-6-phosphate isomerase HCH_06266 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 83646032 Nonpathogen - hypothetical protein HCH_03286 1 None None None 83646091 Common - hypothetical protein HCH_03347 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644272 Nonpathogen - hypothetical protein HCH_01420 1 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 83645610 Nonpathogen - hypothetical protein HCH_02842 4 None None None 83647338 Common - Methylated DNA-protein cysteine methyltransferase HCH_04649 201 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 83648155 Nonpathogen - hypothetical protein HCH_05503 1 None None None 83644124 Nonpathogen - hypothetical protein HCH_01265 1 None None None 83643431 Common - ABC-type Mn/Zn transport system, ATPase component HCH_00536 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 83645888 Common - 7-keto-8-aminopelargonate synthetase and related enzyme HCH_03134 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83645273 Common - Regulatory P domain of the subtilisin-like proprotein convertases and other protease HCH_02477 22 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 83643522 Common - hypothetical protein HCH_00631 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 83642996 Common - probable secreted endoclucanase precursor HCH_00085 42 COG3291 COG3291, FOG: PKD repeat General function prediction only 83647082 Nonpathogen - protein of unknown fuction (DUF1328) HCH_04387 1 COG5487 COG5487, Small integral membrane protein Function unknown 83649639 Common - Transposase HCH_07034 28 COG5433 COG5433, Transposase DNA replication, recombination, and repair 83643097 Common - probable GntR family transcriptional regulator HCH_00190 217 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83644449 Nonpathogen - hypothetical protein HCH_01602 2 None None None 83647638 Nonpathogen - hypothetical protein HCH_04959 2 None None None 83646024 Common - type II secretion target YopN-like protein HCH_03277 15 None None None 83643644 Common - Na+/H+ antiporter NhaD and related arsenite Permease HCH_00757 41 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 83645792 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_03036 143 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83647744 Common - predicted membrane protein HCH_05071 55 COG4327 COG4327, Predicted membrane protein Function unknown 83649445 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs HCH_06834 217 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83645459 Common mtaP 5'-methylthioadenosine phosphorylase HCH_02681 164 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 83646780 Nonpathogen - hypothetical protein HCH_04077 1 None None None 83643131 Common - Nucleoside-binding outer membrane protein HCH_00226 18 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 83643454 Common - probable membrane protein, transporter-related HCH_00560 25 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 83645619 Common - Integrase HCH_02852 49 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 83645612 Nonpathogen - Permease of the major facilitator superfamily HCH_02845 5 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 83647687 Common - protein containing tetratricopeptide repeat HCH_05012 3 None None None 83645952 Nonpathogen - hypothetical protein HCH_03200 1 None None None 83647526 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_04843 52 COG0456 RimI, Acetyltransferases General function prediction only 83643535 Common - hypothetical protein HCH_00644 78 COG1434 COG1434, Uncharacterized conserved protein Function unknown 83645926 Nonpathogen - hypothetical protein HCH_03173 1 None None None 83646082 Common - hypothetical protein HCH_03337 76 COG1742 COG1742, Uncharacterized conserved protein Function unknown 83644251 Common - Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid HCH_01398 113 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 83643601 Common - Nitric oxide reductase large subunit HCH_00713 75 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 83643048 Common thiS thiamine biosynthesis protein ThiS HCH_00139 24 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 83644895 Nonpathogen - hypothetical protein HCH_02074 1 None None None 83643890 Common - Cytochrome c553 HCH_01015 66 COG2863 COG2863, Cytochrome c553 Energy production and conversion 83647946 Common - hypothetical protein HCH_05282 67 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 83644132 Common - FOG: TPR repeat, SEL1 subfamily HCH_01274 102 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 83647380 Common - Membrane protein involved in the export of O-antigen and teichoic acid HCH_04692 97 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83647316 Common - AraC-type DNA-binding domain-containing protein HCH_04627 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83644386 Common fba fructose-1,6-bisphosphate aldolase HCH_01538 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 83648559 Common - ATPase with chaperone activity, ATP-binding subunit HCH_05918 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83649442 Common - ABC-type Fe3+-siderophore transport system, permease component HCH_06831 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83644835 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_02011 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83643726 Common - Transposase and inactivated derivatives HCH_00843 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643001 Common - Sortase (surface protein transpeptidase) HCH_00090 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 83645209 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase HCH_02409 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 83644426 Nonpathogen - hypothetical protein HCH_01580 1 None None None 83648956 Common - NAD-dependent aldehyde dehydrogenase HCH_06320 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83645069 Nonpathogen - hypothetical protein HCH_02253 1 None None None 83648999 Nonpathogen - hypothetical protein HCH_06364 1 None None None 83647097 Common - hypothetical protein HCH_04402 8 None None None 83644807 Nonpathogen - hypothetical protein HCH_01984 3 None None None 83649512 Common - ABC-type dipeptide transport system, periplasmic component HCH_06904 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83644771 Common aruF arginine N-succinyltransferase, alpha subunit HCH_01948 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 83646940 Nonpathogen - hypothetical protein HCH_04243 1 None None None 83646601 Common - hypothetical protein HCH_03885 3 None None None 83643068 Common - ABC-type proline/glycine betaine transport system, permease component HCH_00159 147 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 83644579 Common minD septum site-determining protein MinD HCH_01743 145 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 83644785 Common - ABC-type multidrug transport system, ATPase component HCH_01962 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83647555 Common - predicted dehydrogenase and related protein HCH_04874 182 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 83645877 Common - ABC-type oligopeptide transport system, ATPase component HCH_03123 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 83643254 Common - hypothetical protein HCH_00352 20 COG2170 COG2170, Uncharacterized conserved protein Function unknown 83647203 Nonpathogen - hypothetical protein HCH_04512 1 None None None 83646537 Common - putative toxin YafO HCH_10014 5 None None None 83644763 Common - Phytoene dehydrogenase and related protein HCH_01940 100 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83649398 Common - hypothetical protein HCH_06784 5 None None None 83645659 Common - phage portal protein, lambda family HCH_02895 32 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 83643271 Nonpathogen - hypothetical protein HCH_00370 1 None None None 83649092 Common - Transcriptional regulator HCH_06458 129 COG1609 PurR, Transcriptional regulators Transcription 83645594 Common - Dienelactone hydrolase and related enzyme HCH_02826 104 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83643813 Common - TRAP-type uncharacterized transport system, periplasmic component HCH_00933 74 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 83643821 Nonpathogen - hypothetical protein HCH_00943 1 None None None 83647281 Common - uncharacterized membrane protein HCH_04590 87 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 83649060 Nonpathogen - hypothetical protein HCH_06425 1 None None None 83647631 Common - predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component HCH_04952 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 83644859 Nonpathogen - hypothetical protein HCH_02034 1 None None None 83643995 Common - ABC-type oligopeptide transport system, periplasmic component HCH_01127 212 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 83646827 Common - predicted flavoprotein HCH_04127 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 83646115 Nonpathogen - hypothetical protein HCH_03374 1 None None None 83648630 Common gcvH2 glycine cleavage system H protein HCH_05990 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 83648489 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_05849 151 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83644120 Common - ABC-type antimicrobial peptide transport system, permease component HCH_01261 168 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 83648232 Nonpathogen - hypothetical protein HCH_05583 1 None None None 83644410 Common - Esterase/lipase HCH_01563 100 COG0657 Aes, Esterase/lipase Lipid metabolism 83644900 Nonpathogen - hypothetical protein HCH_02079 2 None None None 83646380 Common - Molecular chaperone HCH_03650 80 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83647487 Common - Thiol-disulfide isomerase and thioredoxins HCH_04803 11 None None None 83648949 Common - putative translation initiation inhibitor, yjgF family HCH_06312 187 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 83648517 Common ftsZ cell division protein FtsZ HCH_05877 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 83645421 Common - Acyl dehydratase HCH_02642 93 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83648391 Common - Acyl-CoA dehydrogenase HCH_05750 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83647795 Nonpathogen - hypothetical protein HCH_05124 1 None None None 83648626 Common - Phosphoserine phosphatase HCH_05985 68 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 83649023 Nonpathogen - hypothetical protein HCH_06388 1 None None None 83646098 Nonpathogen - hypothetical protein HCH_03354 1 None None None 83647108 Common - MoxR-like ATPase HCH_04414 75 COG0714 COG0714, MoxR-like ATPases General function prediction only 83642992 Nonpathogen - hypothetical protein HCH_00081 2 None None None 83646996 Common - hypothetical protein HCH_04299 45 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 83648227 Nonpathogen - hypothetical protein HCH_05577 1 None None None 83645753 Common - probable transcriptional regulator, AraC family HCH_02995 21 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645856 Nonpathogen - hypothetical protein HCH_03100 1 None None None 83647845 Common fliQ flagellar biosynthesis protein FliQ HCH_05177 125 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 83643676 Common - hypothetical protein HCH_00791 44 COG5483 COG5483, Uncharacterized conserved protein Function unknown 83647047 Nonpathogen - hypothetical protein HCH_04351 1 None None None 83645693 Common - hypothetical protein HCH_02931 18 None None None 83646778 Common fliI1 flagellum-specific ATP synthase HCH_04075 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 83646043 Common - ABC-type sugar transport system, permease component HCH_03298 154 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83647852 Common - FOG: HPt domain HCH_05184 18 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 83645377 Common - hypothetical protein HCH_02595 6 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 83643810 Nonpathogen - hypothetical protein HCH_00930 1 None None None 83645507 Common - predicted acyltransferase HCH_02732 117 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83645766 Nonpathogen - hypothetical protein HCH_03008 1 None None None 83647985 Common ptsN PTS IIA-like nitrogen-regulatory protein PtsN HCH_05323 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 83644696 Common - Septum formation initiator HCH_01868 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 83648059 Common - Lysine 2,3-aminomutase HCH_05400 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 83647460 Common - hypothetical protein HCH_04776 9 None None None 83645408 Common - FOG: TPR repeat HCH_02628 76 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83643196 Common - predicted signal transduction protein with a C-terminal ATPase domain HCH_00293 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 83643390 Common - predicted CoA-binding protein HCH_00493 114 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 83643226 Nonpathogen - hypothetical protein HCH_00324 1 None None None 83648135 Common - integral membrane protein, DUF6 family HCH_05482 5 None None None 83648690 Nonpathogen - hypothetical protein HCH_06049 1 None None None 83647413 Common - Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family HCH_04725 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 83648456 Nonpathogen - hypothetical protein HCH_05815 1 None None None 83643159 Common - Amidases related to nicotinamidase HCH_00256 135 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83642969 Nonpathogen - hypothetical protein HCH_00057 1 None None None 83648076 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, permease component HCH_05418 167 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 83644348 Nonpathogen - hypothetical protein HCH_01500 1 None None None 83649544 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06937 90 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649344 Nonpathogen - hypothetical protein HCH_06728 1 None None None 83645606 Nonpathogen - hypothetical protein HCH_02838 1 None None None 83644852 Common - short-chain alcohol dehydrogenase-like protein HCH_02028 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83649322 Common oadA2 pyruvate carboxylase subunit B HCH_06704 180 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 83643855 Nonpathogen - hypothetical protein HCH_00978 1 None None None 83646902 Nonpathogen - hypothetical protein HCH_04205 1 None None None 83647895 Common - hypothetical protein HCH_05230 33 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 83645067 Nonpathogen - hypothetical protein HCH_02251 1 None None None 83648845 Common rplP 50S ribosomal protein L16 HCH_06210 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 83647758 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_05087 205 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83648498 Common lgt prolipoprotein diacylglyceryl transferase HCH_05858 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 83643264 Nonpathogen - hypothetical protein HCH_00362 1 None None None 83645881 Common - ABC-type oligopeptide transport system, periplasmic component HCH_03127 209 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 83645908 Common - hypothetical protein HCH_03155 2 None None None 83649333 Common - hypothetical protein HCH_06716 19 COG5293 COG5293, Uncharacterized protein conserved in bacteria Function unknown 83645830 Common deoC deoxyribose-phosphate aldolase HCH_03074 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 83649327 Common - ABC-type sugar transport system, periplasmic component HCH_06710 23 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83648246 Common - hypothetical protein HCH_05597 37 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 83643355 Common - Chemotaxis protein histidine kinase and related kinase HCH_00455 156 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83648725 Common - putative threonine efflux protein HCH_06087 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83644187 Common - predicted transcriptional regulator HCH_01329 25 COG2944 COG2944, Predicted transcriptional regulator Transcription 83647351 Nonpathogen - hypothetical protein HCH_04662 1 None None None 83647557 Nonpathogen - hypothetical protein HCH_04876 1 None None None 83648265 Nonpathogen - hypothetical protein HCH_05617 2 None None None 83642970 Common - strictosidine synthase family protein HCH_00058 26 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 83643319 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_00419 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83643793 Common - Sterol desaturase HCH_00913 63 COG3000 ERG3, Sterol desaturase Lipid metabolism 83648418 Common - enoyl-CoA hydratase HCH_05777 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83645075 Nonpathogen - hypothetical protein HCH_02259 1 None None None 83647787 Common - Deacetylases, including yeast histone deacetylase and acetoin utilization protein HCH_05116 146 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 83648830 Common rpsM 30S ribosomal protein S13 HCH_06196 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 83647086 Nonpathogen - hypothetical protein HCH_04391 2 None None None 83648644 Common aroQ2 3-dehydroquinate dehydratase HCH_06004 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 83644948 Common - hypothetical protein HCH_02129 73 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 83645676 Nonpathogen - hypothetical protein HCH_02912 1 None None None 83645488 Common prpD 2-methylcitrate dehydratase HCH_02712 58 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 83645386 Nonpathogen - hypothetical protein HCH_02604 4 None None None 83645895 Common - Leucine-rich repeat (LRR) protein HCH_03142 42 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 83644294 Nonpathogen - hypothetical protein HCH_01443 1 None None None 83648897 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_06261 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83645313 Common - ABC-type uncharacterized transport system, permease component HCH_02521 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 83649293 Common - hypothetical protein HCH_06672 2 None None None 83643552 Common - hypothetical protein HCH_00661 21 None None None 83644885 Common - protein of unknown function (DUF1329) HCH_02064 18 None None None 83645381 Common - hypothetical protein HCH_02599 14 None None None 83646808 Common - predicted permease, DMT superfamily HCH_04108 142 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83645104 Common rhlB ATP-dependent RNA helicase HCH_02291 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83645724 Common - Polyketide synthase modules and related protein HCH_02963 208 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83644710 Common - hypothetical protein HCH_01883 2 COG5245 DYN1, Dynein, heavy chain Cytoskeleton 83646252 Nonpathogen - hypothetical protein HCH_03517 1 None None None 83649535 Common - Ribonucleotide reductase, beta subunit HCH_06928 132 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 83649219 Common - AraC-type DNA-binding domain-containing protein HCH_06593 111 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646741 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_04036 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83649539 Common - probable pilus-assembl protein PilC HCH_06932 33 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 83649132 Common - AraC-type DNA-binding domain-containing protein HCH_06501 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83647041 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_04345 8 COG0456 RimI, Acetyltransferases General function prediction only 83645650 Common - probable phage protein HCH_02885 5 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 83643307 Common - hypothetical protein HCH_00406 9 None None None 83645314 Common - ABC-type oligopeptide transport system, periplasmic component HCH_02522 143 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 83648617 Common rpmE ribosomal protein L31 HCH_05975 145 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 83647805 Nonpathogen - hypothetical protein HCH_05135 1 None None None 83645668 Nonpathogen - hypothetical protein HCH_02904 1 None None None 83646120 Common - protein containing EF-hand calciumn-binding domain HCH_03380 25 None None None 83649233 Common - FKBP-type peptidyl-prolyl cis-trans isomerases 2 HCH_06609 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 83645574 Common - hypothetical protein HCH_02806 21 None None None 83646454 Common - hypothetical protein HCH_03730 34 None None None 83644537 Nonpathogen - hypothetical protein HCH_01699 3 None None None 83645912 Common - hypothetical protein HCH_03159 68 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83643622 Common - hypothetical protein HCH_00734 46 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 83645121 Common sixA1 Phosphohistidine phosphatase SixA HCH_02308 68 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 83642962 Common - hypothetical protein HCH_00050 4 None None None 83643327 Common - hypothetical protein HCH_00427 8 COG4278 COG4278, Uncharacterized conserved protein Function unknown 83648770 Nonpathogen - hypothetical protein HCH_06132 1 None None None 83646862 Nonpathogen - hypothetical protein HCH_04165 1 None None None 83648217 Common - protein containing SWIM Zn-chelating domain HCH_05567 15 COG4715 COG4715, Uncharacterized conserved protein Function unknown 83645261 Common - probable cellulase HCH_02464 35 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 83644976 Nonpathogen - hypothetical protein HCH_02156 1 None None None 83646315 Nonpathogen - hypothetical protein HCH_03583 1 None None None 83649475 Common - hypothetical protein HCH_06867 23 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83647145 Common pta phosphate acetyltransferase HCH_04451 176 COG0280 Pta, Phosphotransacetylase Energy production and conversion 83648027 Common - SAM-dependent methyltransferase HCH_05368 167 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83648707 Nonpathogen - hypothetical protein HCH_06068 1 None None None 83649181 Common - Deacetylases, including yeast histone deacetylase and acetoin utilization protein HCH_06553 155 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 83648185 Common - uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides HCH_05533 37 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 83648852 Common rplC Ribosomal protein L3 HCH_06217 241 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 83649115 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_06484 25 COG2153 ElaA, Predicted acyltransferase General function prediction only 83645715 Nonpathogen - hypothetical protein HCH_02953 1 None None None 83648568 Common pilY1 Tfp pilus assembly protein, tip-associated adhesin PilY1 HCH_05927 32 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 83647205 Common - ABC-type branched-chain amino acid transport system, ATPase component HCH_04514 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83645395 Common recR recombination protein RecR HCH_02615 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 83645026 Common potB spermidine/putrescine ABC transporter membrane protein HCH_02208 207 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 83644932 Common - hypothetical protein HCH_02113 32 None None None 83648175 Common - hypothetical protein HCH_05523 15 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 83646648 Nonpathogen - hypothetical protein HCH_03938 5 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 83644058 Common - Pirin-related protein HCH_01193 147 COG1741 COG1741, Pirin-related protein General function prediction only 83647358 Nonpathogen - hypothetical protein HCH_04669 1 None None None 83649420 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06807 19 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647789 Nonpathogen - hypothetical protein HCH_05118 1 None None None 83648100 Common pspC phage shock protein pspC HCH_05445 26 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 83645006 Common - hypothetical protein HCH_02188 42 None None None 83646395 Common - predicted phosphohydrolase HCH_03665 9 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83646638 Nonpathogen - hypothetical protein HCH_03927 1 None None None 83647641 Common - hypothetical protein HCH_04962 4 None None None 83647201 Nonpathogen - hypothetical protein HCH_04510 1 None None None 83643619 Common - Glutamine synthetase HCH_00731 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83643850 Common - Transcriptional regulator HCH_00973 164 COG1522 Lrp, Transcriptional regulators Transcription 83648127 Nonpathogen - hypothetical protein HCH_05474 1 None None None 83648503 Common - flagellar motor protein PomA HCH_05863 105 COG1291 MotA, Flagellar motor component Cell motility and secretion 83644245 Common - uncharacterized enzyme involved in pigment biosynthesis HCH_01392 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83643393 Nonpathogen - hypothetical protein HCH_00496 1 None None None 83645259 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_02462 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83645631 Nonpathogen - hypothetical protein HCH_02864 1 None None None 83648478 Common - hypothetical protein HCH_05838 44 COG2921 COG2921, Uncharacterized conserved protein Function unknown 83647361 Common - Serine/threonine protein kinase HCH_04672 183 COG1262 COG1262, Uncharacterized conserved protein Function unknown 83647971 Nonpathogen - hypothetical protein HCH_05309 1 None None None 83647129 Nonpathogen - hypothetical protein HCH_04435 1 None None None 83645045 Common - predicted integral membrane protein HCH_02228 20 COG5615 COG5615, Predicted integral membrane protein Function unknown 83644821 Nonpathogen - hypothetical protein HCH_01997 5 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 83648561 Common - Pseudouridylate synthases, 23S RNA-specific HCH_05920 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83648719 Common - ABC-type sugar transport system, permease component HCH_06080 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83647384 Nonpathogen - hypothetical protein HCH_04696 1 None None None 83645269 Common tal2 transaldolase B HCH_02473 174 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 83643290 Common - probable phage protein HCH_00389 10 None None None 83645903 Nonpathogen - hypothetical protein HCH_03150 1 None None None 83649148 Common - ABC-type sugar transport system, periplasmic component HCH_06518 53 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83647232 Nonpathogen - hypothetical protein HCH_04542 1 None None None 83645684 Common - hypothetical protein HCH_02920 2 None None None 83646680 Common - hypothetical protein HCH_03971 3 None None None 83645010 Nonpathogen - hypothetical protein HCH_02193 1 None None None 83646957 Common lipH Lipase chaperone HCH_04260 17 COG5380 LimK, Lipase chaperone Posttranslational modification, protein turnover, chaperones 83645353 Nonpathogen - hypothetical protein HCH_02563 3 None None None 83646327 Nonpathogen - hypothetical protein HCH_03596 1 None None None 83643231 Common - hypothetical protein HCH_00329 7 None None None 83644798 Common - hypothetical protein HCH_01975 4 None None None 83646759 Common - Rhodanese-related sulfurtransferase HCH_04054 44 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83649051 Common - FOG: WD40 repeat HCH_06416 43 COG2319 COG2319, FOG: WD40 repeat General function prediction only 83643714 Common - probable pectate lyase HCH_00831 11 None None None 83648236 Common - Transcriptional regulator HCH_05586 88 COG1309 AcrR, Transcriptional regulator Transcription 83643669 Common - predicted signal transduction protein containing sensor and EAL domains HCH_00783 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83647244 Common - phage prohead protease, HK97 family HCH_04554 42 COG3740 COG3740, Phage head maturation protease General function prediction only 83645442 Nonpathogen - hypothetical protein HCH_02664 1 None None None 83644414 Nonpathogen - hypothetical protein HCH_01567 1 None None None 83649112 Nonpathogen - hypothetical protein HCH_06481 1 None None None 83643817 Common - hypothetical protein HCH_00938 3 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 83645426 Common - hypothetical protein HCH_02647 6 None None None 83644583 Common - predicted oxidoreductase (related to aryl-alcohol dehydrogenase) HCH_01747 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83648664 Common - hypothetical protein HCH_06024 3 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 83649374 Nonpathogen - hypothetical protein HCH_06759 2 None None None 83648872 Common istA3 transposase, IS21 family HCH_06236 73 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 83645205 Common rfe UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase HCH_02404 176 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 83644776 Common - Serine/threonine protein phosphatase HCH_01953 129 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83643404 Common - Protein-tyrosine-phosphatase HCH_00507 22 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83647524 Common - Glycosyltransferase involved in cell wall biogenesis HCH_04840 116 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83648817 Nonpathogen - hypothetical protein HCH_06183 1 None None None 83643833 Common hppD 4-hydroxyphenylpyruvate dioxygenase HCH_00955 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 83649292 Common - AraC-type DNA-binding domain-containing protein HCH_06671 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83643577 Nonpathogen - hypothetical protein HCH_00688 3 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 83643472 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_00579 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644239 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_01386 27 COG0456 RimI, Acetyltransferases General function prediction only 83648432 Common - hypothetical protein HCH_05791 30 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 83643025 Common - Serine/threonine protein kinase HCH_00114 156 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83644114 Common - ABC-type branched-chain amino acid transport system, periplasmic component HCH_01255 147 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83648388 Common - predicted ATPase HCH_05745 37 None None None 83648411 Nonpathogen - hypothetical protein HCH_05770 1 None None None 83646732 Common - Response regulator containing a CheY-like receiver domain and an HD-GYP domain HCH_04027 212 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83648686 Common - Microcystin-dependent protein HCH_10025 34 COG4675 MdpB, Microcystin-dependent protein Function unknown 83648739 Common apaH diadenosine tetraphosphatase HCH_06101 99 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 83649305 Nonpathogen - hypothetical protein HCH_06685 1 None None None 83645153 Common infA translation initiation factor IF-1 HCH_02340 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 83648297 Common - hypothetical protein HCH_05649 9 None None None 83649081 Common - fructose-1,6-bisphosphatase HCH_06446 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 83649387 Common - probable phage protein HCH_06773 11 None None None 83649302 Common - predicted phosphohydrolase HCH_06682 12 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 83649310 Common - Ca2+/Na+ antiporter HCH_06691 136 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 83642932 Common - Glucose/sorbosone dehydrogenase HCH_00019 105 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 83648604 Common hemE uroporphyrinogen decarboxylase HCH_05963 176 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 83643888 Common - Transcriptional regulator HCH_01013 52 COG1309 AcrR, Transcriptional regulator Transcription 83649528 Nonpathogen - hypothetical protein HCH_06921 1 None None None 83647752 Common murI glutamate racemase HCH_05080 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 83645778 Common - uncharacterized copper-binding protein HCH_03022 34 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 83646785 Common flgI flagellar basal body P-ring protein HCH_04082 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 83644027 Common - Sugar kinase, ribokinase family HCH_01160 176 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 83644008 Nonpathogen - hypothetical protein HCH_01141 1 None None None 83648610 Common pilQ type 4 fimbrial biogenesis protein PilQ HCH_05969 141 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 83644032 Nonpathogen - hypothetical protein HCH_01165 1 None None None 83643589 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_00700 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83643673 Nonpathogen - hypothetical protein HCH_00787 1 None None None 83645798 Common - uncharacterized protein with SCP/PR1 domains HCH_03042 57 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 83646322 Common - Outer membrane protein W HCH_03590 72 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 83643126 Nonpathogen - hypothetical protein HCH_00221 1 None None None 83645298 Nonpathogen - hypothetical protein HCH_02506 1 None None None 83644565 Common lolB outer membrane lipoprotein LolB HCH_01728 50 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 83646505 Nonpathogen - hypothetical protein HCH_03783 1 None None None 83648160 Common - Phosphoenolpyruvate synthase/pyruvate phosphate dikinase HCH_05508 189 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 83645545 Common - hypothetical protein HCH_02772 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 83649447 Common ilvE2 branched-chain amino acid aminotransferase HCH_06836 212 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83646352 Common - Arginase/agmatinase/formimionoglutamate hydrolase, arginase family HCH_03622 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 83647499 Common - Acyl-CoA synthetase (NDP forming) HCH_04815 148 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 83643148 Nonpathogen - hypothetical protein HCH_00243 1 None None None 83644624 Common algU RNA polymerase sigma factor RpoE HCH_01790 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83643041 Nonpathogen - hypothetical protein HCH_00132 1 None None None 83643163 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_00260 108 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83643381 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_00484 134 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83645336 Common - Dissimilatory sulfite reductase (desulfoviridin), gamma subunit HCH_02545 59 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 83643741 Common - Methyl-accepting chemotaxis protein HCH_00858 46 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 83647286 Common - ATPase involved in DNA repair HCH_04595 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83646613 Nonpathogen - hypothetical protein HCH_03899 1 None None None 83645418 Nonpathogen - hypothetical protein HCH_02639 1 None None None 83648859 Common rpoB DNA-directed RNA polymerase subunit beta HCH_06224 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 83649317 Common - hypothetical protein HCH_06699 24 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 83643330 Common - hypothetical protein HCH_00430 117 COG1801 COG1801, Uncharacterized conserved protein Function unknown 83644363 Common - predicted exonuclease of the beta-lactamase fold involved in RNA processing HCH_01515 128 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 83645533 Common - hypothetical protein HCH_02759 64 COG3272 COG3272, Uncharacterized conserved protein Function unknown 83648838 Common rpsH 30S ribosomal protein S8 HCH_06202 237 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 83644158 Common garK Glycerate kinase HCH_01301 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 83646111 Common - Adenylate cyclase, family 3 HCH_03370 45 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 83646176 Common - 3-hydroxyacyl-CoA dehydrogenase HCH_03438 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 83645132 Common - hypothetical protein HCH_02319 12 None None None 83647497 Common - Carboxylesterase type B HCH_04813 64 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 83647738 Nonpathogen - hypothetical protein HCH_05064 1 None None None 83649524 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_06917 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83649408 Common - Isopenicillin N synthase and related dioxygenases HCH_06794 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 83649618 Nonpathogen - hypothetical protein HCH_07013 1 None None None 83648357 Nonpathogen - hypothetical protein HCH_05711 1 None None None 83645017 Common - hypothetical protein HCH_10038 6 None None None 83647454 Common - Transcriptional regulator HCH_04770 79 COG1309 AcrR, Transcriptional regulator Transcription 83646757 Common - Regulator of competence-specific genes HCH_04052 11 None None None 83647651 Common uvrB excinuclease ABC subunit B HCH_04971 230 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 83649557 Common - Long-chain fatty acid transport protein HCH_06950 78 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 83643153 Nonpathogen - hypothetical protein HCH_00250 1 None None None 83646984 Nonpathogen - hypothetical protein HCH_04287 2 None None None 83647400 Common - Diadenosine tetraphosphatase and related serine/threonine protein phosphatase HCH_04712 33 None None None 83646517 Common - Glutathione S-transferase HCH_03794 78 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83644927 Nonpathogen - hypothetical protein HCH_02108 1 None None None 83648552 Common - predicted membrane protein HCH_05911 78 COG2717 COG2717, Predicted membrane protein Function unknown 83646596 Nonpathogen - hypothetical protein HCH_03879 1 None None None 83649314 Common - Small-conductance mechanosensitive channel HCH_06695 204 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83647768 Common - hypothetical protein HCH_05097 2 COG5613 COG5613, Uncharacterized conserved protein Function unknown 83646650 Nonpathogen - hypothetical protein HCH_03940 1 None None None 83646816 Nonpathogen - hypothetical protein HCH_04116 4 None None None 83648756 Common - hypothetical protein HCH_06118 13 None None None 83643848 Common - hypothetical protein HCH_00970 30 COG3287 COG3287, Uncharacterized conserved protein Function unknown 83646572 Common - predicted GTPase HCH_03855 21 COG0486 ThdF, Predicted GTPase General function prediction only 83648541 Common - Ribosomal protein S9 HCH_05901 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 83643967 Common xdhC Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family HCH_01097 100 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 83649430 Common - Sugar kinase, ribokinase family HCH_06817 54 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83645325 Common - predicted inner membrane peptidase HCH_02534 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83647026 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04330 17 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648210 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_05560 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83646294 Common - hypothetical protein HCH_03562 5 None None None 83648353 Common - hypothetical protein HCH_05707 4 None None None 83644601 Common - hypothetical protein HCH_01766 21 None None None 83647190 Common - ABC-type Fe3+ transport system, permease component HCH_04498 207 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 83648482 Common rodA rod shape-determining protein RodA HCH_05842 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 83649258 Common - Fructose-2,6-bisphosphatase HCH_06635 30 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 83643011 Common - predicted sulfurtransferase HCH_00100 14 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 83648443 Common - Transcriptional regulator HCH_05802 155 COG1522 Lrp, Transcriptional regulators Transcription 83646118 Common - hypothetical protein HCH_03378 40 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 83644532 Common - Na+/H+ antiporter HCH_01694 62 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 83647433 Common sdhB succinate dehydrogenase iron-sulfur subunit HCH_04746 201 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 83643218 Common - hypothetical protein HCH_00316 6 None None None 83643633 Common - Acyl-CoA hydrolase HCH_00745 125 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 83643444 Common - putative transcriptional regulator HCH_00550 129 COG1678 COG1678, Putative transcriptional regulator Transcription 83643828 Common - predicted membrane protein HCH_00950 34 COG2339 COG2339, Predicted membrane protein Function unknown 83648349 Common - hypothetical protein HCH_05704 21 COG5351 COG5351, Uncharacterized protein conserved in bacteria Function unknown 83643904 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_01032 175 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83649684 Common gidB methyltransferase GidB HCH_07082 197 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 83646823 Nonpathogen - hypothetical protein HCH_04123 2 None None None 83647967 Common hisC histidinol-phosphate aminotransferase HCH_05304 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 83646852 Common - Permease of the major facilitator superfamily HCH_04153 5 None None None 83646912 Common - hypothetical protein HCH_04215 22 None None None 83645737 Common dsdA D-serine dehydratase HCH_02978 43 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 83646418 Nonpathogen - hypothetical protein HCH_03689 1 None None None 83646011 Common - Type III secretory pathway, component EscS HCH_03262 118 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 83646050 Common - FOG: TPR repeat HCH_03305 144 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 83645946 Common - RTX toxins and related Ca2+-binding protein HCH_03195 117 None None None 83647115 Common - Transcriptional regulator HCH_04421 46 COG1522 Lrp, Transcriptional regulators Transcription 83645652 Nonpathogen - hypothetical protein HCH_02887 1 None None None 83648219 Common - hypothetical protein HCH_05569 15 None None None 83643116 Common - ABC-type sugar transport system, periplasmic component HCH_00210 45 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83644446 Nonpathogen - hypothetical protein HCH_01599 1 None None None 83646374 Common - ABC-type uncharacterized transport system, periplasmic component HCH_03644 34 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 83647714 Common - hypothetical protein HCH_05041 96 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 83649046 Nonpathogen - hypothetical protein HCH_06411 1 COG3212 COG3212, Predicted membrane protein Function unknown 83644865 Common - ABC-type multidrug transport system, ATPase and permease components HCH_02042 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83643987 Nonpathogen - hypothetical protein HCH_01119 2 None None None 83647476 Common - Beta-glucanase/Beta-glucan synthetase HCH_04792 57 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 83647623 Common xseA exodeoxyribonuclease VII, large subunit HCH_04944 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 83644052 Nonpathogen - hypothetical protein HCH_01187 2 None None None 83644717 Common rnfD predicted NADH:ubiquinone oxidoreductase, subunit RnfD HCH_01891 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 83644492 Common - 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) HCH_01648 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 83647661 Common - Prephenate dehydratase HCH_04981 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 83648191 Nonpathogen - probable two-component response regulator HCH_05540 3 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83644306 Nonpathogen - hypothetical protein HCH_01456 1 None None None 83643310 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases HCH_00409 140 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 83649654 Common - Transposase and inactivated derivatives HCH_07052 6 None None None 83645564 Common - hypothetical protein HCH_02795 10 None None None 83646942 Common - hypothetical protein HCH_04245 9 COG2267 PldB, Lysophospholipase Lipid metabolism 83643498 Common - hypothetical protein HCH_00605 4 None None None 83643928 Common - Glycosyltransferase HCH_01056 188 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83644339 Common - Saccharopine dehydrogenase and related protein HCH_01491 31 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 83645090 Common ccoO cytochrome c oxidase, cbb3-type, subunit II HCH_02275 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 83647863 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_05196 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83649501 Common - hypothetical protein HCH_06893 45 None None None 83648192 Nonpathogen - hypothetical protein HCH_05541 1 None None None 83648014 Common lnt apolipoprotein N-acyltransferase HCH_05352 168 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 83647516 Common - CMP-N-acetylneuraminic acid synthetase HCH_04832 79 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 83644095 Common folP dihydropteroate synthase HCH_01233 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 83645837 Common - Phosphoserine phosphatase HCH_03081 78 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 83646558 Common - predicted phosphoribosyltransferase HCH_03840 37 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 83644262 Common - predicted metal-sulfur cluster biosynthetic enzyme HCH_01409 138 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 83645173 Nonpathogen - hypothetical protein HCH_02362 1 None None None 83643286 Common - hypothetical protein HCH_00385 4 None None None 83646134 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_03394 129 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83645097 Common dsbD Thiol:disulfide interchange protein HCH_02282 131 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83646192 Common - ABC-type Fe3+-hydroxamate transport system, periplasmic component HCH_03455 79 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 83649010 Common - DNA repair protein HCH_06374 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83645342 Common trpS tryptophanyl-tRNA synthetase HCH_02552 228 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83647335 Common - hypothetical protein HCH_04646 15 None None None 83647309 Common - Permease of the major facilitator superfamily HCH_04619 97 None None None 83643706 Common - hypothetical protein HCH_00823 58 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83646792 Common fliR1 Flagellar biosynthesis pathway, component FliR HCH_04089 87 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 83645092 Common - predicted hydrolase of the alpha/beta-hydrolase fold HCH_02277 37 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 83647763 Common - hypothetical protein HCH_05092 60 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83646300 Nonpathogen - hypothetical protein HCH_03569 1 None None None 83645568 Common - putative GTPase (G3E family) HCH_02800 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 83645983 Nonpathogen - hypothetical protein HCH_03233 1 None None None 83644089 Common carA carbamoyl phosphate synthase small subunit HCH_01227 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 83648620 Common hslV ATP-dependent protease peptidase subunit HCH_05979 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 83648884 Common - predicted membrane protein HCH_06247 96 COG1981 COG1981, Predicted membrane protein Function unknown 83649224 Common - hypothetical protein HCH_06599 10 None None None 83649179 Nonpathogen - hypothetical protein HCH_06551 1 None None None 83645535 Common - Serine phosphatase RsbU, regulator of sigma subunit HCH_02761 132 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 83647906 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase HCH_05241 165 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 83643736 Common - ABC-type proline/glycine betaine transport system, permease component HCH_00853 179 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 83646463 Nonpathogen - hypothetical protein HCH_03739 1 None None None 83644830 Common uvrD UvrD/REP helicase family protein HCH_02006 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 83646481 Common - Membrane-fusion protein HCH_03759 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83649429 Nonpathogen - hypothetical protein HCH_06816 1 None None None 83649454 Common - Bacterioferritin-associated ferredoxin HCH_06843 27 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 83648364 Common - Site-specific DNA methylase HCH_05719 35 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 83646401 Common - hypothetical protein HCH_03671 3 None None None 83643703 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00820 15 None None None 83643969 Common xdhA Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A HCH_01099 123 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 83646223 Common - predicted NAD/FAD-binding protein HCH_03487 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 83647609 Common - probable sensor protein/histidine kinase containing His Kinase A domain HCH_04930 3 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647648 Common - hypothetical protein HCH_04968 20 None None None 83647222 Common - hypothetical protein HCH_04532 5 None None None 83648310 Common - hypothetical protein HCH_05663 4 None None None 83648927 Common - Xaa-Pro aminopeptidase HCH_06289 185 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 83647019 Nonpathogen - hypothetical protein HCH_04323 1 None None None 83647562 Common - AraC-type DNA-binding domain-containing protein HCH_04881 61 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645625 Nonpathogen - hypothetical protein HCH_02857 1 None None None 83647425 Common scpB segregation and condensation protein B HCH_04737 159 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 83647836 Common - Chemotaxis protein histidine kinase and related kinase HCH_05168 154 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83649286 Common - Glucose/sorbosone dehydrogenase HCH_06664 119 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 83648300 Common - hypothetical protein HCH_05652 11 COG5449 COG5449, Uncharacterized conserved protein Function unknown 83648547 Nonpathogen - hypothetical protein HCH_05907 2 None None None 83644439 Common lysE Lysine efflux permease HCH_01592 78 COG1279 COG1279, Lysine efflux permease General function prediction only 83648260 Nonpathogen - hypothetical protein HCH_05612 1 None None None 83643719 Nonpathogen - hypothetical protein HCH_00836 1 None None None 83644810 Common - probable phage protein HCH_01987 24 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83645457 Common - Beta-glucosidase-related Glycosidase HCH_02679 174 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 83646878 Common - putative intracellular protease/amidase HCH_04181 93 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83643370 Nonpathogen - hypothetical protein HCH_00470 1 None None None 83643016 Common - Coenzyme F420-reducing hydrogenase, alpha subunit HCH_00105 92 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 83646831 Common - Cation/multidrug efflux pump HCH_04131 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83646950 Common - ATPase with chaperone activity, ATP-binding subunit HCH_04253 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83644984 Common - predicted double-glycine peptidase HCH_02165 34 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 83647163 Common tgt queuine tRNA-ribosyltransferase HCH_04469 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 83647070 Nonpathogen - hypothetical protein HCH_04375 1 None None None 83643339 Common malS periplasmic alpha-amylase precursor HCH_00439 154 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83649590 Common - predicted N-acetylglucosamine kinase HCH_06985 39 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 83649670 Common glmS D-fructose-6-phosphate amidotransferase HCH_07068 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 83647136 Common - hypothetical protein HCH_04442 3 None None None 83648825 Common uvrA excinuclease ABC, A subunit HCH_06191 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 83649030 Common - predicted Rossmann fold nucleotide-binding protein involved in DNA uptake HCH_10004 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 83646625 Common aroQ1 chorismate mutase HCH_03913 10 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 83647511 Common - predicted ATPase of the PP-loop superfamily implicated in cell cycle control HCH_04827 28 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 83643602 Common - cell morphogenesis/cell wall metabolism regulator HCH_00714 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 83645434 Common - ATP-dependent transcriptional regulator HCH_02655 111 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 83643662 Common - Rubredoxin HCH_00776 116 COG1773 COG1773, Rubredoxin Energy production and conversion 161897899 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha HCH_01862 184 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 83643878 Common - probable mercuric reductase HCH_01003 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83647602 Common ruvA Holliday junction DNA helicase RuvA HCH_04923 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 83643801 Nonpathogen - hypothetical protein HCH_00921 2 None None None 83647885 Common - Response regulator HCH_05220 222 COG4566 TtrR, Response regulator Signal transduction mechanisms 83649019 Nonpathogen - hypothetical protein HCH_06385 1 None None None 83649037 Common - hypothetical protein HCH_06401 59 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 83647960 Common - ABC-type dipeptide transport system, periplasmic component HCH_05297 18 None None None 83643953 Common - hypothetical protein HCH_01083 14 None None None 83649139 Nonpathogen - hypothetical protein HCH_06508 1 None None None 83649263 Common - hypothetical protein HCH_06640 9 None None None 83647445 Common - Universal stress protein UspA and related nucleotide-binding protein HCH_04760 151 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83647708 Common - uncharacterized MobA-related protein HCH_05035 84 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 83646790 Common flhA1 Flagellar biosynthesis pathway, component FlhA HCH_04087 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 83648395 Common - acyl-CoA synthetase HCH_05754 174 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83647530 Common - Transcriptional regulator HCH_04847 145 COG1522 Lrp, Transcriptional regulators Transcription 83647212 Common ureB Urea amidohydrolase (urease) beta subunit HCH_04522 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 83646121 Nonpathogen - hypothetical protein HCH_03381 2 None None None 83643433 Common malE maltose ABC transporter periplasmic protein HCH_00538 70 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 83645113 Common - hypothetical protein HCH_02300 5 None None None 83649288 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_06667 19 None None None 83644516 Common - Chitinase HCH_01673 38 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 83645723 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02962 211 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83644469 Nonpathogen - hypothetical protein HCH_01623 1 None None None 83643734 Common betA choline dehydrogenase HCH_00851 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 83647958 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase HCH_05295 29 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83643515 Common - Integrase HCH_00623 108 COG0582 XerC, Integrase DNA replication, recombination, and repair 83644503 Common - Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family 1 HCH_01659 222 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 83648760 Common - Acyl-CoA dehydrogenase HCH_06122 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83647546 Nonpathogen - hypothetical protein HCH_04865 1 None None None 83649076 Nonpathogen - hypothetical protein HCH_06441 1 None None None 83649064 Nonpathogen - hypothetical protein HCH_06429 1 None None None 83644196 Common - hypothetical protein HCH_01339 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 83643582 Common cydA Cytochrome bd-type quinol oxidase, subunit 1 HCH_00693 164 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 83646925 Nonpathogen - hypothetical protein HCH_04228 2 None None None 83647260 Common - hypothetical protein HCH_10017 3 None None None 83648823 Common - Single-stranded DNA-binding protein HCH_06189 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 83643530 Common - Enoyl-CoA hydratase/carnithine racemase HCH_00639 134 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83644264 Common csdB Selenocysteine lyase HCH_01412 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 83644639 Common - predicted pyrophosphatase HCH_01808 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 83648445 Common glcF glycolate oxidase iron-sulfur subunit HCH_05804 172 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 83646645 Common gspG general secretion pathway protein G HCH_03935 74 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 83646894 Nonpathogen - hypothetical protein HCH_04197 1 None None None 83648576 Common ribF riboflavin biosynthesis protein RibF HCH_05934 211 COG0196 RibF, FAD synthase Coenzyme metabolism 83644300 Nonpathogen - hypothetical protein HCH_01450 1 None None None 83648468 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_05828 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83646309 Nonpathogen - hypothetical protein HCH_03577 4 None None None 83649357 Common - Retron-type reverse transcriptase HCH_06742 39 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83644520 Common - probable deoxygenase HCH_01677 12 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83643897 Common dut dUTPase HCH_01022 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 83645633 Nonpathogen - hypothetical protein HCH_02866 1 None None None 83644728 Common avtA valine--pyruvate transaminase HCH_01903 133 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 83644099 Common - hypothetical protein HCH_01237 180 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 83644077 Common - hypothetical protein HCH_01214 28 None None None 83644145 Common - predicted epimerase, PhzC/PhzF-like protein HCH_01287 118 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 83645085 Common - copper-translocating P-type ATPase HCH_02269 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 83644165 Common - putative GTPase (G3E family) HCH_01308 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 83648681 Common - hypothetical protein HCH_06041 3 None None None 83645088 Common ccoP cytochrome c oxidase, cbb3-type, subunit III HCH_02273 90 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 83646473 Nonpathogen - hypothetical protein HCH_03750 1 None None None 83649197 Common - Permease of the major facilitator superfamily HCH_06569 18 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83644741 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_01916 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645851 Common xylB xylulokinase HCH_03095 168 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 83646285 Nonpathogen - hypothetical protein HCH_03553 1 None None None 83644682 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_01853 162 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 83646442 Nonpathogen - hypothetical protein HCH_03716 1 None None None 83645812 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03056 11 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83642978 Common - hypothetical protein HCH_00067 5 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 83644629 Common lepA GTP-binding protein LepA HCH_01797 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 83644955 Common rluC Pseudouridylate synthases, 23S RNA-specific HCH_02136 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83648737 Nonpathogen - hypothetical protein HCH_06099 1 None None None 83649395 Common - probable phage protein HCH_06781 12 None None None 83647535 Nonpathogen - hypothetical protein HCH_04852 1 None None None 83648474 Nonpathogen - hypothetical protein HCH_05834 1 None None None 83646842 Common - Chemotaxis protein histidine kinase and related kinase HCH_04142 53 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83648222 Nonpathogen - hypothetical protein HCH_05572 1 None None None 83648366 Common - hypothetical protein HCH_05723 2 None None None 83648694 Common - Asparagine synthase (glutamine-hydrolyzing) HCH_06054 131 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83649331 Common - hypothetical protein HCH_06715 9 None None None 83646901 Common - ABC-type sugar transport system, periplasmic component HCH_04204 31 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83645032 Common - putative threonine efflux protein HCH_02214 107 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83648997 Common rdgB non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family HCH_06362 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 83643423 Common - predicted deacylase HCH_00528 56 COG3608 COG3608, Predicted deacylase General function prediction only 83647898 Common - uncharacterized protein (competence- and mitomycin-induced) HCH_05233 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 83649170 Nonpathogen - hypothetical protein HCH_06541 1 None None None 83646183 Common - ABC-type siderophore export system, fused ATPase and permease components HCH_03446 248 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 83644215 Common - ABC-type proline/glycine betaine transport system, ATPase component HCH_01361 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 83643658 Common phoB Phosphate regulon transcriptional regulatory protein phoB HCH_00771 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83648115 Common - ABC-type hemin transport system, periplasmic component HCH_05461 139 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 83645823 Common - hypothetical protein HCH_03067 5 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 83646204 Common - probable DNA methylase HCH_03467 9 None None None 83644011 Nonpathogen - hypothetical protein HCH_01144 1 None None None 83646761 Nonpathogen - hypothetical protein HCH_04056 1 None None None 83643076 Common - hypothetical protein HCH_00167 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 83646202 Common - hypothetical protein HCH_03465 9 None None None 83642942 Common fmt methionyl-tRNA formyltransferase HCH_00029 227 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 83648940 Common - hypothetical protein HCH_06303 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 83643356 Common - Chemotaxis signal transduction protein HCH_00456 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83646881 Common - hypothetical protein HCH_04184 58 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 83648457 Common - Phospholipase/lecithinase/hemolysin HCH_05816 43 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 83647699 Common - predicted hydrolase (metallo-beta-lactamase superfamily) HCH_05025 22 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 83643923 Nonpathogen - probable O-antigen polymerase HCH_01051 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 83644917 Common - Rhs family protein HCH_02097 35 None None None 83649469 Nonpathogen - hypothetical protein HCH_06861 4 None None None 83645186 Common - hypothetical protein HCH_02378 22 None None None 83647982 Common - ABC-type (unclassified) transport system, ATPase component HCH_05319 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 83646849 Common - maltodextrin glucosidase HCH_04150 150 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83644758 Common - Methyl-accepting chemotaxis protein HCH_01935 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83646611 Nonpathogen - hypothetical protein HCH_03895 1 None None None 83644719 Common rnfB predicted NADH:ubiquinone oxidoreductase, subunit RnfB HCH_01893 125 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 83646930 Common - sigma 54-dependent transcriptional activator HCH_04233 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83647237 Nonpathogen - hypothetical protein HCH_04547 1 None None None 83648939 Common - hypothetical protein HCH_06302 25 COG1723 COG1723, Uncharacterized conserved protein Function unknown 83644736 Common - hypothetical protein HCH_01911 32 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 83647502 Common fliD Flagellar capping protein HCH_04818 108 COG1345 FliD, Flagellar capping protein Cell motility and secretion 83644993 Common - hypothetical protein HCH_02175 2 None None None 83643084 Common - predicted amidohydrolase HCH_00176 65 COG0388 COG0388, Predicted amidohydrolase General function prediction only 83647447 Common - ATPase components of ABC transporters with duplicated ATPase domains HCH_04762 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83649379 Common - Mu-like prophage FluMu protein gp28 HCH_06764 25 COG5484 COG5484, Uncharacterized conserved protein Function unknown 83646089 Nonpathogen - hypothetical protein HCH_03345 1 None None None 83647299 Common - hypothetical protein HCH_04608 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 83648084 Common - hypothetical protein HCH_05427 29 None None None 83648461 Common - NAD(P)H-nitrite reductase HCH_05820 210 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 83644484 Common - hypothetical protein HCH_01639 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 83647346 Common - hypothetical protein HCH_04657 8 None None None 83648484 Common - hypothetical protein HCH_05844 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 83647761 Common ptsP phosphotransferase system enzyme I PtsP HCH_05090 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 83645759 Common - replicative DNA helicase HCH_03001 37 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 83644619 Common - predicted signal transduction protein HCH_01785 51 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83647719 Nonpathogen - hypothetical protein HCH_05046 2 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 83644640 Common - hypothetical protein HCH_01809 6 None None None 83644219 Common - Acetyl-CoA acetyltransferase HCH_01365 176 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83642928 Common - transcription regulator (ArsR family) HCH_00015 94 COG0640 ArsR, Predicted transcriptional regulators Transcription 83646412 Nonpathogen - hypothetical protein HCH_03682 1 None None None 83648633 Common - hypothetical protein HCH_05993 27 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 83644734 Common - DnaA family protein HCH_01909 198 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 83643200 Common dapF diaminopimelate epimerase HCH_00298 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 83646403 Nonpathogen - hypothetical protein HCH_03673 1 None None None 83647120 Common - Mannose-6-phosphate isomerase HCH_04426 38 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 83646676 Common - tRNA nucleotidyltransferase/poly(A) polymerase HCH_03967 7 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 83645858 Nonpathogen - hypothetical protein HCH_03101 1 None None None 83643241 Common - predicted membrane protein HCH_00339 34 COG3752 COG3752, Predicted membrane protein Function unknown 83644890 Common - putative NADPH-quinone reductase (modulator of drug activity B) HCH_02069 46 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 83645439 Nonpathogen - hypothetical protein HCH_02660 1 None None None 83649214 Nonpathogen - hypothetical protein HCH_06587 1 None None None 83647723 Nonpathogen - hypothetical protein HCH_05050 4 None None None 83647039 Common - hypothetical protein HCH_04343 19 None None None 83645582 Common - hypothetical protein HCH_02814 38 None None None 83644172 Common - hypothetical protein HCH_10005 21 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83647390 Nonpathogen - hypothetical protein HCH_04703 1 None None None 83648861 Common rplJ Ribosomal protein L10 HCH_06226 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 83647969 Common hisG ATP phosphoribosyltransferase catalytic subunit HCH_05306 207 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 83645073 Nonpathogen - hypothetical protein HCH_02257 1 None None None 83644200 Common hisH1 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit HCH_01345 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 83644461 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_01614 65 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83647033 Common - hypothetical protein HCH_04337 2 None None None 83643745 Common - Cysteine synthase HCH_00863 2 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 83644567 Common - hypothetical protein HCH_01730 2 None None None 83648965 Nonpathogen - hypothetical protein HCH_06329 2 None None None 83646961 Common - FOG: CheY-like receiver HCH_04264 181 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643043 Common - hypothetical protein HCH_00134 21 None None None 83646556 Common - Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 HCH_03838 122 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 83649566 Common - hypothetical protein HCH_06960 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 83644254 Common - hypothetical protein HCH_01401 33 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 83649647 Common - hypothetical protein HCH_07042 14 None None None 83646008 Common - Transposase and inactivated derivatives HCH_03259 44 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644914 Nonpathogen - hypothetical protein HCH_02094 2 None None None 83643474 Nonpathogen - hypothetical protein HCH_00581 2 None None None 83645586 Common cas1 CRISPR-associated protein Cas1 HCH_02818 99 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83648000 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B HCH_05338 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 83649097 Common - hypothetical protein HCH_06464 5 None None None 83647791 Nonpathogen - hypothetical protein HCH_05121 1 None None None 83644384 Common edp D-erythrose-4-phosphate dehydrogenase HCH_01536 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 83643635 Common - TRAP-type mannitol/chloroaromatic compound transport system, small permease component HCH_00747 69 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 83643691 Common - putative chitin/cellulose binding protein HCH_00807 23 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 83643536 Common - FOG: CheY-like receiver HCH_00645 118 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83649547 Common - Outer membrane protein HCH_06940 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83646439 Common - FOG: EAL domain HCH_03713 223 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83646018 Common - Transposase and inactivated derivatives HCH_03270 38 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643698 Common - hypothetical protein HCH_00814 4 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 83644963 Common fabD malonyl CoA-acyl carrier protein transacylase HCH_02143 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 83648533 Common - putative lipoprotein HCH_05894 44 COG3107 LppC, Putative lipoprotein General function prediction only 83645981 Nonpathogen - hypothetical protein HCH_03231 1 None None None 83646383 Nonpathogen - hypothetical protein HCH_03653 1 None None None 83649339 Nonpathogen - hypothetical protein HCH_06723 1 None None None 83648970 Common istB4 IstB helper protein, IS21 family HCH_06334 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 83648901 Common panB2 3-methyl-2-oxobutanoate hydroxymethyltransferase HCH_06264 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 83642957 Common - hypothetical protein HCH_00045 4 None None None 83645057 Common - hypothetical protein HCH_02241 62 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 83646544 Nonpathogen - hypothetical protein HCH_03823 1 None None None 83646465 Nonpathogen - hypothetical protein HCH_03741 3 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 83643364 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_00464 5 COG0456 RimI, Acetyltransferases General function prediction only 83644138 Nonpathogen - hypothetical protein HCH_01280 1 None None None 83645050 Common - Nucleoside-diphosphate-sugar epimerase HCH_02234 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83645689 Nonpathogen - hypothetical protein HCH_02926 1 None None None 83649460 Nonpathogen - hypothetical protein HCH_06850 1 None None None 83646333 Common - predicted carbamoyl transferase, NodU family HCH_03603 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 83643256 Common - hypothetical protein HCH_00354 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 83643960 Common - predicted membrane protein HCH_01090 35 COG3748 COG3748, Predicted membrane protein Function unknown 83648978 Common - ATPase components of ABC transporters with duplicated ATPase domains HCH_06342 8 None None None 83646735 Common - FOG: CheY-like receiver HCH_04030 209 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83644438 Common coxI CO dehydrogenase maturation factor HCH_01591 85 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 83643569 Nonpathogen - protein containing tetratricopeptide repeats HCH_00679 3 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83649002 Nonpathogen - hypothetical protein HCH_06367 4 None None None 83646080 Nonpathogen - hypothetical protein HCH_03336 1 None None None 83642950 Common motA Flagellar motor component HCH_00038 109 COG1291 MotA, Flagellar motor component Cell motility and secretion 83646162 Nonpathogen - hypothetical protein HCH_03424 9 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 83647589 Common - Peroxiredoxin HCH_04908 225 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83644526 Common - predicted permease HCH_01685 118 COG0628 PerM, Predicted permease General function prediction only 83646971 Common - TRAP-type mannitol/chloroaromatic compound transport system, small permease component HCH_04274 54 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 83648158 Nonpathogen - hypothetical protein HCH_05506 1 None None None 83646660 Common - Electron transfer flavoprotein, beta subunit HCH_03950 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 83645848 Common - Site-specific recombinase XerC HCH_03092 27 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83646376 Common - Signal transduction histidine kinase HCH_03646 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644288 Nonpathogen - hypothetical protein HCH_01437 1 None None None 83644318 Nonpathogen - hypothetical protein HCH_01470 2 None None None 83645988 Common - SAM-dependent methyltransferase HCH_03238 132 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83646637 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_03926 9 COG0456 RimI, Acetyltransferases General function prediction only 83646455 Common - hypothetical protein HCH_03731 11 None None None 83647004 Common - predicted metal-binding protein related to the C-terminal domain of SecA HCH_04307 89 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 83647077 Nonpathogen - hypothetical protein HCH_04382 2 None None None 83647873 Nonpathogen - hypothetical protein HCH_05207 1 None None None 83643593 Common - Spermidine synthase HCH_00705 36 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 83647030 Common - Signal transduction histidine kinase HCH_04334 130 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646431 Common - Chemotaxis protein, stimulates methylation of MCP protein HCH_03704 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 83644632 Common rnc ribonuclease III HCH_01800 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 83646935 Common - Bacteriophytochrome (light-regulated signal transduction histidine kinase) HCH_04238 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83648524 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase HCH_05885 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 83644205 Common - Periplasmic protease HCH_01350 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 83643647 Common - 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase HCH_00760 128 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 83647941 Common - Tfp pilus assembly protein, major pilin PilA HCH_05277 26 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 83643651 Common - Small-conductance mechanosensitive channel HCH_00764 177 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83645944 Common - hypothetical protein HCH_03191 6 None None None 83647452 Common - hypothetical protein HCH_04767 51 COG2138 COG2138, Uncharacterized conserved protein Function unknown 83649009 Nonpathogen - hypothetical protein HCH_06373 1 None None None 83644169 Nonpathogen - hypothetical protein HCH_01312 1 None None None 83644610 Common xerD tyrosine recombinase XerD HCH_01776 231 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83644457 Common thiQ ABC-type thiamine transport system, ATPase component HCH_01610 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 83649555 Common - Secreted trypsin-like serine protease HCH_06949 39 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 83645929 Common - protein of unknown function (DUF1555) HCH_03176 3 None None None 83644938 Nonpathogen - hypothetical protein HCH_02118 2 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 83646915 Nonpathogen - hypothetical protein HCH_04218 1 None None None 83644101 Common infB translation initiation factor IF-2 HCH_01239 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 83648393 Common - Acetyl/propionyl-CoA carboxylase, alpha subunit HCH_05752 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83646889 Common - Transcriptional regulator HCH_04192 178 COG0583 LysR, Transcriptional regulator Transcription 83647821 Nonpathogen - hypothetical protein HCH_05151 1 None None None 83647336 Common - hypothetical protein HCH_04647 8 None None None 83649275 Common - DNA G:T-mismatch repair endonuclease HCH_06652 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 83645614 Common - Peptide arylation enzyme HCH_02847 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83648801 Common - predicted kinase related to galactokinase and mevalonate kinase HCH_06166 36 COG2605 COG2605, Predicted kinase related to galactokinase and mevalonate kinase General function prediction only 83647230 Nonpathogen - hypothetical protein HCH_04540 1 None None None 83649637 Nonpathogen - hypothetical protein HCH_07032 1 None None None 83643456 Common - Disulfide bond chaperones of the HSP33 family HCH_00562 134 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 83648103 Nonpathogen - hypothetical protein HCH_05448 1 None None None 83644594 Common - Ni,Fe-hydrogenase I small subunit HCH_01759 12 None None None 83648019 Common holA DNA polymerase III, delta subunit HCH_05357 86 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 83643099 Common - putative threonine efflux protein HCH_00192 103 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83648024 Common - hypothetical protein HCH_05362 19 None None None 83644006 Common - uncharacterized protein related to capsule biosynthesis enzyme HCH_01139 58 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 83644902 Nonpathogen - hypothetical protein HCH_02081 1 None None None 83644897 Nonpathogen - hypothetical protein HCH_02076 1 None None None 83649243 Common - Signal transduction histidine kinase HCH_06619 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646241 Common - Leucine-rich repeat (LRR) protein HCH_03505 51 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 83643642 Common - hypothetical protein HCH_00755 10 COG2105 COG2105, Uncharacterized conserved protein Function unknown 83643211 Common - Signal transduction histidine kinase HCH_00309 227 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647843 Common flhB flagellar biosynthesis protein FlhB HCH_05175 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 83648925 Common - AraC-type DNA-binding domain-containing protein HCH_06288 89 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645580 Nonpathogen - hypothetical protein HCH_02812 1 None None None 83646259 Common - Citrate lyase beta subunit HCH_03524 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 83648705 Common - hypothetical protein HCH_06066 11 None None None 83645279 Nonpathogen - hypothetical protein HCH_02486 1 None None None 83643759 Common - AraC-type DNA-binding domain-containing protein HCH_00877 140 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646070 Nonpathogen - hypothetical protein HCH_03325 1 None None None 83644428 Common - predicted acyltransferase HCH_01582 87 COG2153 ElaA, Predicted acyltransferase General function prediction only 83649426 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06813 31 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644122 Common - ABC-type antimicrobial peptide transport system, ATPase component HCH_01263 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83644237 Common - hypothetical protein HCH_01384 12 None None None 83645686 Nonpathogen - phytanoyl-CoA deoxygenase family protein HCH_02921 2 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83645179 Common - FOG: GGDEF domain HCH_02371 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83645972 Nonpathogen - hypothetical protein HCH_03221 1 None None None 83646713 Common mqo malate:quinone oxidoreductase HCH_04006 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 83644540 Nonpathogen - hypothetical protein HCH_01702 1 None None None 83643458 Common - predicted hydrolase (HAD superfamily) HCH_00564 39 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 83647435 Common sdhD Succinate dehydrogenase, hydrophobic anchor subunit HCH_04748 52 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 83644270 Common - hypothetical protein HCH_01419 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 83648566 Common - Tfp pilus assembly protein FimT HCH_10022 32 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 83646539 Common - hypothetical protein HCH_03817 2 None None None 83643451 Nonpathogen - hypothetical protein HCH_00557 1 None None None 83645875 Common - putative NADPH-quinone reductase (modulator of drug activity B) HCH_03121 61 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 83643685 Common mnhF Multisubunit Na+/H+ antiporter, MnhF subunit HCH_00800 46 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 83647668 Common - hypothetical protein HCH_04988 10 None None None 83649573 Common - ABC-type sugar transport system, ATPase components HCH_06968 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83649440 Common - Periplasmic protein TonB, links inner and outer membranes HCH_06827 27 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83643811 Nonpathogen - hypothetical protein HCH_00931 1 None None None 83644837 Common mutM2 Formamidopyrimidine-DNA glycosylase HCH_02013 174 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 83648248 Nonpathogen - hypothetical protein HCH_05599 1 None None None 83644324 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01476 19 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645168 Common - Transposase and inactivated derivatives HCH_02355 44 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643173 Common - Glycosyltransferase involved in cell wall biogenesis HCH_00270 35 None None None 83644042 Common - NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain HCH_01176 143 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 83643154 Nonpathogen - hypothetical protein HCH_00249 1 None None None 83643998 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_01130 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83643295 Common - phage major capsid protein, P2 family HCH_00394 22 None None None 83644761 Common - putative intracellular protease/amidase HCH_01939 141 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 83645281 Nonpathogen - BamHI-like type II restriction endonuclease HCH_10009 3 None None None 83643137 Common - hypothetical protein HCH_00232 34 COG4938 COG4938, Uncharacterized conserved protein Function unknown 83647778 Common yscN type III secretion system ATPase HCH_05107 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 83649062 Common rep ATP-dependent DNA helicase Rep HCH_06427 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 83648373 Common hsdM2 Type I restriction-modification system methyltransferase subunit HCH_05730 150 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 83646096 Common - Transglutaminase-like enzyme, putative cysteine protease HCH_03352 89 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83647959 Common - protein of unknown function (DUF1329) HCH_05296 19 None None None 83647258 Nonpathogen - hypothetical protein HCH_04566 2 None None None 83647672 Common rnt ribonuclease T HCH_04993 55 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83647581 Common - Molybdopterin biosynthesis enzyme HCH_04900 185 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 83645348 Common - Signal transduction histidine kinase HCH_02558 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83643057 Common - hypothetical protein HCH_00148 14 None None None 83648270 Nonpathogen - hypothetical protein HCH_05622 1 None None None 83643997 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_01129 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83648290 Nonpathogen - hypothetical protein HCH_05642 1 None None None 83645304 Common - phospho-2-dehydro-3-heoxyheptonate aldolase HCH_02512 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 83646730 Common - Signal transduction histidine kinase HCH_04025 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83643488 Common - SOS-response transcriptional repressors (RecA-mediated autopeptidase) HCH_00595 24 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 83647485 Nonpathogen - hypothetical protein HCH_04802 1 None None None 83649417 Common - uncharacterized protein related to deoxyribodipyrimidine photolyase HCH_06803 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 83647326 Common ubiG2 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benz oquinol methylase HCH_04637 57 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83644134 Nonpathogen - hypothetical protein HCH_01276 1 None None None 83644591 Common - putative hemolysin HCH_01756 61 COG3176 COG3176, Putative hemolysin General function prediction only 83645424 Nonpathogen - hypothetical protein HCH_02645 1 None None None 83644369 Common - hypothetical protein HCH_01521 122 COG0432 COG0432, Uncharacterized conserved protein Function unknown 83647633 Nonpathogen - hypothetical protein HCH_04954 1 None None None 83642990 Nonpathogen - hypothetical protein HCH_00079 1 None None None 83647595 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_04914 137 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83647423 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_04735 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83648344 Common - Site-specific recombinase HCH_05698 133 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 83646723 Common - hypothetical protein HCH_04017 2 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 83643991 Common - NADH dehydrogenase, FAD-containing subunit HCH_01123 77 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 83644209 Common grxC Glutaredoxin, GrxC family HCH_01355 124 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 83645819 Nonpathogen - hypothetical protein HCH_03063 1 None None None 83647573 Common - predicted phosphohydrolase HCH_04892 96 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 83647095 Nonpathogen - hypothetical protein HCH_04399 1 None None None 83646787 Common flgA Flagellar basal body P-ring biosynthesis protein HCH_04084 5 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 83649209 Common - Highly conserved protein containing a thioredoxin domain HCH_06582 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 83644362 Nonpathogen - hypothetical protein HCH_01514 1 None None None 83648519 Common - Cell division septal protein HCH_05880 72 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 83646998 Common - hypothetical protein HCH_04301 17 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 83647283 Common ppnK inorganic polyphosphate/ATP-NAD kinase HCH_04592 204 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 83646447 Common - hypothetical protein HCH_03721 4 None None None 83645841 Common - Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase HCH_03085 155 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 83647134 Nonpathogen - hypothetical protein HCH_04440 1 None None None 83643823 Common - hypothetical protein HCH_00945 3 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 83648162 Common - Pirin-related protein HCH_05510 145 COG1741 COG1741, Pirin-related protein General function prediction only 83645155 Common - arginyl-tRNA-protein transferase HCH_02342 86 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 83648572 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase HCH_05930 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 83644705 Common - hypothetical protein HCH_01878 18 None None None 83649142 Nonpathogen - hypothetical protein HCH_06511 1 None None None 83647405 Common - Methylase of chemotaxis methyl-accepting protein HCH_04717 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83648093 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_05438 96 COG0456 RimI, Acetyltransferases General function prediction only 83648586 Common - hypothetical protein HCH_05945 73 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 83648450 Common - ABC-type amino acid transport system, permease component HCH_05809 185 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83646829 Common - Signal transduction histidine kinase HCH_04129 140 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83645461 Common mfd transcription-repair coupling factor HCH_02683 233 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 83645138 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_02325 53 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83648220 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_05570 31 COG0456 RimI, Acetyltransferases General function prediction only 83645141 Common - Adenylate cyclase, family 3 HCH_02328 89 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 83647925 Nonpathogen - hypothetical protein HCH_05261 1 None None None 83643273 Nonpathogen - hypothetical protein HCH_00372 1 None None None 83643428 Nonpathogen - hypothetical protein HCH_00533 1 None None None 83648001 Common - 2-methylthioadenine synthetase HCH_05339 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 83649255 Nonpathogen - hypothetical protein HCH_06631 1 None None None 83647857 Common fliJ Flagellar biosynthesis chaperone HCH_05189 14 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 83644421 Common - predicted aminopeptidase HCH_01574 32 COG2234 Iap, Predicted aminopeptidases General function prediction only 83645131 Nonpathogen - hypothetical protein HCH_02318 1 None None None 83643481 Common - Integrase HCH_00588 30 None None None 83642916 Common dnaN DNA polymerase III, beta subunit HCH_00003 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 83643363 Common - Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain HCH_00463 205 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83647749 Common - Hydrolase of the alpha/beta superfamily HCH_05076 113 COG2267 PldB, Lysophospholipase Lipid metabolism 83647291 Common - hypothetical protein HCH_04600 5 None None None 83644230 Nonpathogen - hypothetical protein HCH_01377 1 None None None 83648251 Nonpathogen - hypothetical protein HCH_05604 1 None None None 83643954 Common - hypothetical protein HCH_01084 13 None None None 83645163 Common - ABC-type transport system, involved in lipoprotein release, permease component HCH_02350 181 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 83645642 Nonpathogen - hypothetical protein HCH_02877 1 None None None 83648689 Nonpathogen - hypothetical protein HCH_06048 1 None None None 83648330 Common - Holliday junction resolvasome, endonuclease subunit HCH_05684 11 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 83644129 Common - Transcriptional regulator HCH_01271 141 COG2186 FadR, Transcriptional regulators Transcription 83644846 Common - hypothetical protein HCH_02022 25 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 83646107 Common napA Anaerobic dehydrogenase, typically selenocysteine-containing HCH_03364 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 83644460 Nonpathogen - hypothetical protein HCH_01613 1 None None None 83647467 Common - uncharacterized protein containing a von Willebrand factor type A (vWA) domain HCH_04783 78 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 83646153 Common - ATPase of the AAA+ class HCH_03415 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 83645978 Nonpathogen - protein containing hemolysin-type calcium-binding repeats HCH_03227 6 None None None 83648815 Common - nucleoside-diphosphate-sugar pyrophosphorylase HCH_06180 151 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 83647850 Common fliL Flagellar basal body-associated protein HCH_05182 29 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 83646076 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs HCH_03332 183 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83643008 Nonpathogen - hypothetical protein HCH_00097 1 None None None 83646499 Common - Rhs family protein HCH_03777 55 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83646899 Nonpathogen - hypothetical protein HCH_04202 2 None None None 83649155 Nonpathogen - hypothetical protein HCH_06526 1 None None None 83644142 Nonpathogen - hypothetical protein HCH_01284 1 None None None 83649481 Common - predicted membrane protein HCH_06873 25 COG3205 COG3205, Predicted membrane protein Function unknown 83645570 Common - Spermidine/putrescine-binding periplasmic protein HCH_02802 123 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83649069 Common - TRAP-type C4-dicarboxylate transport system, periplasmic component HCH_06434 73 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83646313 Nonpathogen - hypothetical protein HCH_03581 1 None None None 83645365 Common - Transposase and inactivated derivatives HCH_02575 13 None None None 83643462 Common - Fatty-acid desaturase HCH_00568 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 83648334 Common - hypothetical protein HCH_05688 8 None None None 83649149 Nonpathogen - protein containing tetratricopeptide repeats HCH_06519 5 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83648042 Common - uncharacterized host factor I protein HCH_05383 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 83643313 Nonpathogen - hypothetical protein HCH_00413 1 None None None 83644222 Common - hypothetical protein HCH_01368 11 None None None 83648206 Nonpathogen - hypothetical protein HCH_05556 1 None None None 83648550 Common - Transposase and inactivated derivatives HCH_05910 45 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644641 Common ppc phosphoenolpyruvate carboxylase HCH_01811 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 83645039 Common - hypothetical protein HCH_02222 19 None None None 83644854 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02030 195 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83646549 Common - Amidases related to nicotinamidase HCH_03829 68 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83647174 Common flgD2 Flagellar hook capping protein HCH_04480 119 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 83645703 Nonpathogen - hypothetical protein HCH_02941 1 None None None 83645060 Nonpathogen - hypothetical protein HCH_02245 4 None None None 83646340 Nonpathogen - hypothetical protein HCH_03610 1 None None None 83644647 Common - SAM-dependent methyltransferase HCH_01818 49 None None None 83644370 Nonpathogen - hypothetical protein HCH_01522 1 None None None 83643943 Common ubiF 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase HCH_01072 126 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 83644945 Common - group II intron-encoding maturase HCH_02126 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83645746 Nonpathogen - protein containing tetratricopeptide repeat HCH_02987 1 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83644064 Nonpathogen - hypothetical protein HCH_01201 1 None None None 83644277 Common - hypothetical protein HCH_01425 19 COG3794 PetE, Plastocyanin Energy production and conversion 83643033 Common - Fatty acid desaturase HCH_00123 36 COG3239 DesA, Fatty acid desaturase Lipid metabolism 83647177 Common - Nitroreductase HCH_04484 81 COG0778 NfnB, Nitroreductase Energy production and conversion 83648753 Nonpathogen - hypothetical protein HCH_06115 1 None None None 83646026 Nonpathogen - hypothetical protein HCH_03279 1 COG5613 COG5613, Uncharacterized conserved protein Function unknown 83646145 Common - predicted transcriptional regulator HCH_03406 130 COG0789 SoxR, Predicted transcriptional regulators Transcription 83646135 Common - hypothetical protein HCH_03395 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 83644700 Common surE acid phosphatase SurE HCH_01872 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 83646495 Nonpathogen - hypothetical protein HCH_03773 1 None None None 83649649 Common - ATPase involved in DNA repair HCH_07044 36 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 83644654 Common - AraC-type DNA-binding domain-containing protein HCH_01825 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645472 Common - soluble pyridine nucleotide transhydrogenase HCH_02695 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83647736 Nonpathogen - hypothetical protein HCH_05063 1 None None None 83643566 Nonpathogen - hypothetical protein HCH_00676 1 None None None 83643728 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_00844 146 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83649212 Common - Phage shock protein A (IM30), suppresses sigma54-dependent transcription HCH_06585 17 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 83646863 Nonpathogen - hypothetical protein HCH_04166 1 None None None 83643301 Nonpathogen - hypothetical protein HCH_00400 1 None None None 83649028 Common - hypothetical protein HCH_10031 7 None None None 83645808 Nonpathogen - hypothetical protein HCH_03052 1 None None None 83645358 Nonpathogen - hypothetical protein HCH_02568 1 None None None 83646563 Common - FOG: EAL domain HCH_03845 225 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83649567 Common - Flagellin and related hook-associated protein HCH_06962 111 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83644547 Common rnr1 ribonuclease R HCH_01709 201 COG0557 VacB, Exoribonuclease R Transcription 83648908 Common rpsU 30S ribosomal protein S21 HCH_06271 137 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 83646703 Nonpathogen - hypothetical protein HCH_03996 1 None None None 83649164 Nonpathogen - hypothetical protein HCH_06535 1 None None None 83648983 Nonpathogen - hypothetical protein HCH_06347 3 None None None 83648036 Common purA adenylosuccinate synthetase HCH_05377 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 83648315 Common - phage portal protein, lambda family HCH_05670 38 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 83645479 Common msbA lipid A export ATP-binding/permease protein MsbA HCH_02703 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83647742 Nonpathogen - hypothetical protein HCH_05069 2 None None None 83646393 Common - predicted membrane protein HCH_03663 40 COG4325 COG4325, Predicted membrane protein Function unknown 83646670 Common - probable DNA binding protein containing WGR domain HCH_03961 7 None None None 83648854 Common tuf1 elongation factor Tu HCH_06219 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 83648215 Common - MoxR-like ATPase HCH_05565 54 COG0714 COG0714, MoxR-like ATPases General function prediction only 83647702 Common hsdM1 Type I restriction-modification system methyltransferase subunit HCH_05029 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 83643384 Common - predicted Permease HCH_00486 132 COG0679 COG0679, Predicted permeases General function prediction only 83645717 Common - hypothetical protein HCH_02956 14 None None None 83649656 Nonpathogen - hypothetical protein HCH_07054 2 None None None 83649562 Common - predicted nucleoside-diphosphate-sugar epimerase HCH_06956 108 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83646341 Nonpathogen - hypothetical protein HCH_03611 1 None None None 83649503 Common - hypothetical protein HCH_06896 36 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 83643206 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_00304 195 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83649456 Common - hypothetical protein HCH_06846 2 None None None 83649006 Nonpathogen - hypothetical protein HCH_06371 5 None None None 83648381 Nonpathogen - hypothetical protein HCH_05738 1 None None None 83648029 Common bioF 8-amino-7-oxononanoate synthase HCH_05370 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83646279 Common - Thiol:disulfide interchange protein HCH_03547 134 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83648759 Common - Transcriptional regulator HCH_06121 159 COG0583 LysR, Transcriptional regulator Transcription 83648839 Common rpsN Ribosomal protein S14 HCH_06204 207 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 83649423 Common - predicted dioxygenase of extradiol dioxygenase family HCH_06810 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 83646217 Nonpathogen - hypothetical protein HCH_03481 2 None None None 83644707 Nonpathogen - protein containing tetratricopeptide repeat (TPR1, TPR2) HCH_01880 1 COG2433 COG2433, Uncharacterized conserved protein Function unknown 83648832 Common secY preprotein translocase subunit SecY HCH_06197 237 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 83646136 Nonpathogen - hypothetical protein HCH_03396 1 None None None 83646466 Nonpathogen - hypothetical protein HCH_03742 1 None None None 83648407 Common - Preprotein translocase subunit SecA (ATPase, RNA helicase) HCH_05766 9 None None None 83645344 Common - Osmosensitive K+ channel histidine kinase HCH_02554 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 83647888 Common - Alkylated DNA repair protein HCH_05223 41 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 83646945 Common - hypothetical protein HCH_04248 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 83644291 Nonpathogen - hypothetical protein HCH_01440 1 None None None 83649222 Common - Phage shock protein A (IM30), suppresses sigma54-dependent transcription HCH_06597 32 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 83646697 Common - hypothetical protein HCH_03989 11 COG4273 COG4273, Uncharacterized conserved protein Function unknown 83646858 Common - hypothetical protein HCH_04159 14 None None None 83643650 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_00763 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83644982 Common - Bacterial nucleoid DNA-binding protein HCH_02163 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83646127 Common - Nitrous oxidase accessory protein HCH_03387 51 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 83649463 Common - Universal stress protein UspA and related nucleotide-binding protein HCH_06853 55 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83644308 Common - hypothetical protein HCH_01459 27 None None None 83644287 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_01436 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83646959 Common - hypothetical protein HCH_04262 17 None None None 83646329 Common - Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II HCH_03599 195 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83643429 Common - Poly(3-hydroxyalkanoate) synthetase HCH_00534 77 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 83649671 Common glmU UDP-N-acetylglucosamine pyrophosphorylase HCH_07069 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 83642926 Common - ABC-type dipeptide transport system, periplasmic component HCH_00013 217 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83646798 Common - Outer membrane protein V HCH_04097 22 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 161897898 Common dcd deoxycytidine triphosphate deaminase HCH_01900 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 83646421 Common - Cysteine synthase HCH_03693 223 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83644631 Common - hypothetical protein HCH_01799 14 None None None 83644981 Common lon2 ATP-dependent protease La HCH_02162 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 83648003 Nonpathogen - hypothetical protein HCH_05341 2 None None None 83645015 Common - predicted Fe-S protein HCH_02198 25 COG3313 COG3313, Predicted Fe-S protein General function prediction only 83643944 Common - hypothetical protein HCH_01073 122 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 83643504 Nonpathogen - hypothetical protein HCH_00611 1 None None None 83645720 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02959 216 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83646952 Common - Lactoylglutathione lyase HCH_04255 57 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 83647024 Common - hypothetical protein HCH_04328 18 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83645043 Nonpathogen - hypothetical protein HCH_02225 1 None None None 83644337 Common - protein containing IQ calmodulin-binding motif HCH_01489 19 None None None 83647477 Common - Chitinase HCH_04793 42 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 83645130 Nonpathogen - hypothetical protein HCH_02317 1 None None None 83644372 Common rbn ribonuclease BN-like family protein HCH_01524 84 COG1295 Rbn, Predicted membrane protein Function unknown 83649382 Common - probable phage small terminase subunit HCH_06767 21 None None None 83647907 Common - Outer membrane protein HCH_05242 71 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 83649138 Common - hypothetical protein HCH_06507 29 COG2606 EbsC, Uncharacterized conserved protein Function unknown 83649502 Common - hypothetical protein HCH_06894 18 None None None 83644280 Common - Signal transduction histidine kinase HCH_01429 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83645224 Common - Transcriptional regulator HCH_02426 193 COG0583 LysR, Transcriptional regulator Transcription 83644823 Nonpathogen - hypothetical protein HCH_01999 1 None None None 83643018 Common - probable hydrogen dehydrogenase HCH_00107 180 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 83648347 Common - DNA repair protein HCH_05701 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83643800 Common atpB1 ATP synthase F0, A subunit HCH_00920 193 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 83643013 Common - hypothetical protein HCH_00102 7 None None None 83649667 Common - Tn7-like transposition protein C HCH_07065 18 None None None 83644051 Common - predicted protein-disulfide isomerase HCH_01186 35 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 83643129 Common recC exodeoxyribonuclease V, gamma subunit HCH_00224 67 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 83648230 Nonpathogen - hypothetical protein HCH_05582 1 None None None 83649047 Common - predicted outer membrane lipoprotein HCH_06412 22 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 83643807 Nonpathogen - hypothetical protein HCH_00927 1 None None None 83645420 Common - hypothetical protein HCH_02641 3 None None None 83645112 Common penP Beta-lactamase class A HCH_02299 65 COG2367 PenP, Beta-lactamase class A Defense mechanisms 83643035 Common - hypothetical protein HCH_00125 37 COG5587 COG5587, Uncharacterized conserved protein Function unknown 83644224 Common - uncharacterized protein involved in response to NO HCH_01371 53 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 83648434 Nonpathogen - hypothetical protein HCH_05793 1 None None None 83643689 Common mnhA putative monovalent cation/H+ antiporter subunit A HCH_00804 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 83643704 Nonpathogen - hypothetical protein HCH_00822 1 None None None 83645094 Nonpathogen - hypothetical protein HCH_02279 5 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 83645962 Nonpathogen - hypothetical protein HCH_03211 1 None None None 83646837 Nonpathogen - hypothetical protein HCH_04137 1 None None None 83646483 Nonpathogen - hypothetical protein HCH_03761 1 None None None 83643030 Common - Dienelactone hydrolase and related enzyme HCH_00119 117 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83644670 Common - predicted P-loop ATPase fused to an acetyltransferase HCH_01842 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 83647654 Common - Orotidine-5'-phosphate decarboxylase HCH_04974 169 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 83649205 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_06578 20 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83645537 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase HCH_02763 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83646266 Common - Rhs family protein HCH_03533 65 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83647307 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase HCH_04617 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83643694 Common panB1 3-methyl-2-oxobutanoate hydroxymethyltransferase HCH_00810 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 83644263 Common - hypothetical protein HCH_01411 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 83645211 Common - predicted glycosyltransferase HCH_02411 86 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 83645839 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_03083 37 None None None 83648099 Common pspB phage shock protein B HCH_05444 22 None None None 83645514 Common - Glycosyltransferase HCH_02738 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83647343 Common - Permease of the major facilitator superfamily HCH_04654 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83647224 Nonpathogen - hypothetical protein HCH_04534 1 None None None 83647607 Common - hypothetical protein HCH_04928 72 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 83646272 Common - TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component HCH_03539 114 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83649162 Nonpathogen - hypothetical protein HCH_06533 6 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 83645372 Common - Membrane-associated lipoprotein involved in thiamine biosynthesis HCH_02590 140 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 83647140 Common - Mg-dependent DNase HCH_04446 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 83649585 Common - ABC-type sugar transport system, permease component HCH_06980 167 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83649169 Nonpathogen - hypothetical protein HCH_06540 1 None None None 83643353 Common - Methyl-accepting chemotaxis protein HCH_00453 14 None None None 83647495 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04811 21 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643280 Common - probable phage protein HCH_00379 12 None None None 83644377 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase HCH_01529 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 83643906 Common - Signal transduction histidine kinase, nitrogen specific HCH_01034 220 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 83646608 Nonpathogen - hypothetical protein HCH_03892 4 None None None 83647242 Common - hypothetical protein HCH_04552 8 None None None 83645294 Nonpathogen - hypothetical protein HCH_02502 10 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83647312 Nonpathogen - hypothetical protein HCH_04622 1 None None None 83644712 Common - predicted flavin-nucleotide-binding protein HCH_01885 34 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 83646056 Common - Transcriptional regulator HCH_03311 43 COG1846 MarR, Transcriptional regulators Transcription 83647698 Common - hypothetical protein HCH_05024 7 None None None 83645470 Common - hypothetical protein HCH_02693 28 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 83649017 Common - Transposase and inactivated derivatives HCH_06382 13 None None None 83643757 Common - hypothetical protein HCH_00875 9 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 83644866 Common - ABC-type multidrug transport system, ATPase and permease components HCH_02044 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83646788 Common flgG1 Flagellar basal body rod protein HCH_04085 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 83648680 Common - hypothetical protein HCH_06040 20 COG3644 COG3644, Uncharacterized protein conserved in bacteria Function unknown 83646152 Common - Subtilisin-like serine protease HCH_03413 34 None None None 83643840 Common cobQ cobyric acid synthase HCH_00962 154 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 83648612 Common pilO Tfp pilus assembly protein PilO HCH_05970 43 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 83645334 Common - Thioredoxin-like protein HCH_02543 41 COG0316 IscA, Uncharacterized conserved protein Function unknown 83647681 Common - stress-induced morphogen HCH_05005 95 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 83647277 Common - protein with unknown function (DUF1329) HCH_04586 19 None None None 83645840 Common phnX phosphonoacetaldehyde hydrolase HCH_03084 42 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 83643447 Common pyrB aspartate carbamoyltransferase catalytic subunit HCH_00553 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 83645276 Common - Transcriptional regulator HCH_02482 173 COG0583 LysR, Transcriptional regulator Transcription 83649125 Common - Cold shock protein HCH_06494 171 COG1278 CspC, Cold shock proteins Transcription 83645762 Common - hypothetical protein HCH_03004 5 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 83646448 Nonpathogen - hypothetical protein HCH_03722 1 None None None 83644326 Common - ADP-ribose pyrophosphatase HCH_01478 103 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 83646086 Common - hypothetical protein HCH_03342 3 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 83647574 Common - Nucleoside-diphosphate-sugar epimerase HCH_04893 188 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83647135 Common - protein containing QXW lectin repeats HCH_04441 31 None None None 83648954 Common - GMP synthase - Glutamine amidotransferase domain HCH_06317 138 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 83644152 Common - ABC-type sugar transport system, permease components HCH_01295 167 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83645573 Nonpathogen - hypothetical protein HCH_02805 1 None None None 83646179 Common - hypothetical protein HCH_03441 5 None None None 83644184 Nonpathogen - hypothetical protein HCH_01326 1 None None None 83646590 Common - ATPase components of ABC transporters with duplicated ATPase domains HCH_03873 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83649406 Common - hypothetical protein HCH_06792 10 None None None 83643285 Nonpathogen - hypothetical protein HCH_00384 1 None None None 83647643 Common - predicted SAM-dependent methyltransferase HCH_04964 144 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 83648400 Nonpathogen - hypothetical protein HCH_05759 2 None None None 83646375 Common - ABC-type uncharacterized transport system, periplasmic component HCH_03645 26 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 83649299 Common - hypothetical protein HCH_06679 9 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 83645832 Common deoD purine nucleoside phosphorylase HCH_03076 93 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 83648727 Nonpathogen - hypothetical protein HCH_06089 1 None None None 83647709 Common - Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein HCH_05036 107 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 83649284 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_06661 180 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83649521 Common - threonine dehydratase HCH_06914 216 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 83647991 Common - predicted membrane protein HCH_05329 55 COG3164 COG3164, Predicted membrane protein Function unknown 83643083 Common - Protocatechuate 3,4-dioxygenase beta subunit HCH_00174 36 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 83646324 Common - hypothetical protein HCH_03593 6 None None None 83646354 Common - Flagellar motor protein HCH_03624 22 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83649319 Common - hypothetical protein HCH_06701 11 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83645548 Common - protein containing fibronectin type III domains HCH_02778 52 None None None 83649507 Common - hypothetical protein HCH_06898 9 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 83645969 Common - Superfamily I DNA and RNA helicase and helicase subunit HCH_03218 93 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 83646615 Common - Transcriptional regulator HCH_03901 191 COG0583 LysR, Transcriptional regulator Transcription 83644498 Common - Transcriptional regulator HCH_01654 128 COG1846 MarR, Transcriptional regulators Transcription 83644880 Common - predicted unusual protein kinase HCH_02059 178 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83646791 Common flhB1 Flagellar biosynthesis pathway, component FlhB HCH_04088 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 83648804 Nonpathogen - hypothetical protein HCH_06169 1 None None None 83644870 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_02049 110 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83645137 Common - Transcriptional regulator HCH_02324 105 COG0583 LysR, Transcriptional regulator Transcription 83647256 Common - probable phage protein HCH_04564 13 None None None 83648527 Common - UDP-N-acetylmuramyl tripeptide synthase HCH_05888 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 83644044 Common istB1 IstB helper protein, IS21 family HCH_01178 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 83647545 Common - predicted carboxypeptidase HCH_04864 29 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 83648110 Common - Signal transduction histidine kinase HCH_05455 207 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 83645654 Nonpathogen - hypothetical protein HCH_02889 1 None None None 83644877 Nonpathogen - hypothetical protein HCH_02056 1 None None None 83643682 Nonpathogen - hypothetical protein HCH_00797 1 None None None 83645196 Common - Glycosyltransferase involved in cell wall biogenesis HCH_02394 25 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83646820 Common - Periplasmic protease HCH_04120 58 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 83646872 Common - FOG: TPR repeat, SEL1 subfamily HCH_04175 223 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 83644038 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01172 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643449 Nonpathogen - protein containing HHH motif HCH_00555 15 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 83645773 Common - predicted aminopeptidase HCH_03015 56 COG2234 Iap, Predicted aminopeptidases General function prediction only 83647192 Nonpathogen - hypothetical protein HCH_04500 1 None None None 83643631 Common uvrD DNA-dependent helicase II HCH_00743 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 83645417 Common - hypothetical protein HCH_02638 3 None None None 83646859 Nonpathogen - hypothetical protein HCH_04160 1 None None None 83646752 Common - Molecular chaperone (small heat shock protein) HCH_04047 160 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 83645170 Nonpathogen - hypothetical protein HCH_02358 3 None None None 83649432 Common - ABC-type sugar transport system, periplasmic component HCH_06819 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83643989 Common - histidyl-tRNA synthetase-related protein HCH_01121 202 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83646728 Nonpathogen - hypothetical protein HCH_04022 1 None None None 83648824 Common - Permease of the major facilitator superfamily HCH_06190 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83646067 Common - Transcriptional regulator HCH_03322 121 COG0583 LysR, Transcriptional regulator Transcription 83646597 Nonpathogen - hypothetical protein HCH_03880 1 None None None 83647560 Nonpathogen - hypothetical protein HCH_04879 1 None None None 83649617 Common - ABC-type multidrug transport system, ATPase and permease components HCH_07012 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83645553 Common - hypothetical protein HCH_02783 3 None None None 83649027 Common - hypothetical protein HCH_06392 3 None None None 83646178 Common - predicted thioesterase involved in non-ribosomal peptide biosynthesis HCH_03440 49 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83644589 Common - FKBP-type peptidyl-prolyl cis-trans isomerases 2 HCH_01755 133 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 83646548 Common - Lactoylglutathione lyase HCH_03828 12 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 83648359 Common - hypothetical protein HCH_05713 21 None None None 83646819 Common - Signal transduction histidine kinase HCH_04119 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83645868 Nonpathogen - hypothetical protein HCH_03113 1 None None None 83647169 Common flgI flagellar basal body P-ring protein HCH_04475 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 83644030 Nonpathogen - hypothetical protein HCH_01163 1 None None None 83647807 Nonpathogen - hypothetical protein HCH_05137 1 None None None 83643169 Common - uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) HCH_00266 108 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 83645206 Common - predicted nucleoside-diphosphate sugar epimerase HCH_02405 152 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83646531 Nonpathogen - hypothetical protein HCH_03810 1 None None None 83645412 Common - Biopolymer transport protein HCH_02633 9 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83646721 Nonpathogen - hypothetical protein HCH_04015 1 None None None 83643142 Common - Membrane-fusion protein HCH_00237 100 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83644975 Common folD 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase HCH_02155 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 83645627 Nonpathogen - hypothetical protein HCH_02860 1 None None None 83649541 Common - hypothetical protein HCH_06934 40 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 83646691 Common - AraC-type DNA-binding domain-containing protein HCH_03982 129 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83643192 Common hemX uncharacterized enzyme of heme biosynthesis HCH_00289 56 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 83649477 Nonpathogen - hypothetical protein HCH_06869 1 None None None 83643189 Common ubiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases HCH_00286 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 83643413 Common - Esterase/lipase HCH_00518 111 COG0657 Aes, Esterase/lipase Lipid metabolism 83645847 Common - probable glycosyl hydrolase HCH_03091 40 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 83644582 Common - Glycosyltransferase HCH_01746 203 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83645005 Common - hypothetical protein HCH_02187 12 None None None 83647443 Common - hypothetical protein HCH_04758 3 None None None 83647619 Common - Cytosine/adenosine deaminases HCH_04940 218 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 83648886 Common - protein containing tetratricopeptide repeats HCH_06249 6 COG5602 SIN3, Histone deacetylase complex, SIN3 component Chromatin structure and dynamics 83645355 Common - thiamine pyrophosphate-requiring enzyme HCH_02565 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83648717 Common - AraC-type DNA-binding domain-containing protein HCH_06078 116 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 83646907 Nonpathogen - hypothetical protein HCH_04210 2 None None None 83643628 Common - Transcriptional regulator HCH_00740 88 COG1737 RpiR, Transcriptional regulators Transcription 83648930 Common - Choline-glycine betaine transporter HCH_06292 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 83645200 Common asnB4 asparagine synthase (glutamine-hydrolyzing) HCH_02399 177 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83647678 Common sbcB exonuclease I HCH_05002 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 83649614 Nonpathogen - hypothetical protein HCH_07009 1 COG1396 HipB, Predicted transcriptional regulators Transcription 83643261 Common - putative protein-S-isoprenylcysteine methyltransferase HCH_00359 47 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 83649553 Common - putative acetyltransferase HCH_06946 45 COG0456 RimI, Acetyltransferases General function prediction only 83647367 Nonpathogen - hypothetical protein HCH_04678 1 None None None 83649083 Common - predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component HCH_06449 83 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 83647817 Common - Cytosine deaminase and related metal-dependent Hydrolase HCH_05147 72 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83644336 Common - hypothetical protein HCH_01487 7 None None None 83645920 Common - Proline racemase HCH_03167 48 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 83644931 Nonpathogen - hypothetical protein HCH_02112 1 None None None 83648239 Common - predicted xylanase/chitin deacetylase HCH_05590 79 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 83648414 Common - predicted dehydrogenase and related protein HCH_05773 134 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 83646813 Nonpathogen - hypothetical protein HCH_04113 1 None None None 83648035 Nonpathogen - hypothetical protein HCH_05376 3 None None None 83643712 Nonpathogen - hypothetical protein HCH_00829 1 None None None 83647356 Common - hypothetical protein HCH_04667 7 None None None 83649304 Nonpathogen - hypothetical protein HCH_06684 1 None None None 83649056 Common - hypothetical protein HCH_06421 3 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 83647616 Common - Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family Hydrolase HCH_04937 61 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 83649367 Common - probable phage protein HCH_06752 10 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 83643328 Nonpathogen - hypothetical protein HCH_00428 1 None None None 83644298 Common - hypothetical protein HCH_01448 73 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83647626 Common - predicted membrane protein HCH_04947 25 COG3821 COG3821, Predicted membrane protein Function unknown 83648909 Common - hypothetical protein HCH_06272 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 83648747 Common - nucleoside-diphosphate-sugar pyrophosphorylase HCH_06109 221 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 83649645 Nonpathogen - hypothetical protein HCH_07040 3 None None None 83647621 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein HCH_04942 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 83644663 Common - ABC-type dipeptide transport system, periplasmic component HCH_01834 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83644939 Common mgsA methylglyoxal synthase HCH_02120 87 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 83649309 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_06689 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645397 Common - hypothetical protein HCH_02617 35 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 83648567 Common - Tfp pilus assembly protein PilE HCH_05926 73 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 83643591 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_00702 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83646496 Nonpathogen - hypothetical protein HCH_03774 1 None None None 83646686 Common - Nucleoside-diphosphate-sugar epimerase HCH_03977 32 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83648924 Nonpathogen - hypothetical protein HCH_06286 1 None None None 83643463 Nonpathogen - hypothetical protein HCH_00570 1 None None None 83645883 Nonpathogen - hypothetical protein HCH_03129 1 None None None 83648495 Common hrpB ATP-dependent helicase HrpB HCH_05855 133 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 83649122 Common - Glutathione S-transferase HCH_06491 71 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83647350 Common - Pseudouridylate synthases, 23S RNA-specific HCH_04661 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83644103 Common truB tRNA pseudouridine synthase B HCH_01241 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 83647081 Common - hypothetical protein HCH_04386 5 None None None 83647854 Nonpathogen - hypothetical protein HCH_05186 1 None None None 83648144 Common - Amino acid transporters HCH_05491 126 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 83649187 Common - Sugar kinase, ribokinase family HCH_06560 71 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83644242 Common - hypothetical protein HCH_01389 8 None None None 83648288 Common - hypothetical protein HCH_05640 15 None None None 83647054 Common - predicted phosphatase HCH_04358 189 COG0546 Gph, Predicted phosphatases General function prediction only 83648374 Common - predicted membrane protein/domain HCH_05731 41 COG1714 COG1714, Predicted membrane protein/domain Function unknown 83643746 Common - predicted membrane protein HCH_00864 17 COG4984 COG4984, Predicted membrane protein Function unknown 83646718 Common narG nitrate reductase, alpha subunit HCH_04011 97 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 83643901 Common argE acetylornithine deacetylase HCH_01029 205 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 83643894 Common rpmB ribosomal protein L28 HCH_01019 169 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 83644056 Common - Phosphodiesterase/alkaline phosphatase D HCH_01191 58 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 83645021 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_02203 35 COG0456 RimI, Acetyltransferases General function prediction only 83645786 Common - predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase HCH_03030 5 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 83649290 Common - Transcriptional regulator HCH_06669 118 COG1846 MarR, Transcriptional regulators Transcription 83644562 Common rplY 50S ribosomal protein L25/general stress protein Ctc HCH_01725 187 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 83643437 Common - Methylase of chemotaxis methyl-accepting protein HCH_00542 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83648899 Common - tRNA nucleotidyltransferase/poly(A) polymerase HCH_06262 210 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 83644112 Common livM leucine/isoleucine/valine transporter permease subunit HCH_01252 132 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83647022 Nonpathogen - hypothetical protein HCH_04326 1 None None None 83646291 Nonpathogen - hypothetical protein HCH_03559 1 None None None 83648718 Common - ABC-type sugar transport system, ATPase components HCH_06079 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83644332 Nonpathogen - protein containing EF hand domain HCH_01484 4 None None None 83643925 Common - Zn-dependent alcohol dehydrogenase, class III HCH_01053 12 None None None 83649048 Common - Transcriptional regulator HCH_06413 86 COG1309 AcrR, Transcriptional regulator Transcription 83643717 Common - hypothetical protein HCH_00834 14 None None None 83645729 Common - uncharacterized protein/domain associated with GTPase HCH_02969 14 COG3597 COG3597, Uncharacterized protein/domain associated with GTPases Function unknown 83649597 Common - hypothetical protein HCH_06992 25 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 83643312 Common - hypothetical protein HCH_00412 2 None None None 83648240 Common - N-glycosyltransferase PgaC HCH_05591 226 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83646015 Nonpathogen - hypothetical protein HCH_03267 1 None None None 83643886 Common - NAD-dependent aldehyde dehydrogenase HCH_01011 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83643219 Nonpathogen - hypothetical protein HCH_00317 1 None None None 83643860 Common - hypothetical protein HCH_00983 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 83649620 Nonpathogen - hypothetical protein HCH_07014 1 None None None 83643539 Common - AraC-type DNA-binding domain-containing protein HCH_00648 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645816 Common - Permease of the major facilitator superfamily HCH_03060 13 None None None 83649156 Common - Leucine-rich repeat (LRR) protein HCH_06527 43 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 83644505 Common - Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain HCH_01662 211 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83647759 Common - Signal transduction histidine kinase HCH_05088 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643332 Common gap2 glyceraldehyde-3-phosphate dehydrogenase, type I HCH_00432 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 83649273 Nonpathogen - hypothetical protein HCH_06650 1 None None None 83644599 Common - Glutaredoxin-related protein HCH_01764 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 83647786 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05115 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643377 Nonpathogen - hypothetical protein HCH_00478 1 None None None 83645909 Common - hypothetical protein HCH_03156 6 None None None 83649496 Common - hypothetical protein HCH_06888 23 None None None 83649600 Common - Nicotinamide mononucleotide transporter HCH_06995 61 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 83643751 Nonpathogen - hypothetical protein HCH_00870 1 None None None 83644483 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_01637 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644119 Common - hypothetical protein HCH_01260 15 None None None 83645675 Nonpathogen - hypothetical protein HCH_02911 1 None None None 83645312 Common - ABC-type uncharacterized transport system, permease component HCH_02520 219 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 83643932 Common - Acyl-CoA dehydrogenase HCH_01061 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83648425 Common - hypothetical protein HCH_05784 20 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83644699 Common - hypothetical protein HCH_01871 85 COG0585 COG0585, Uncharacterized conserved protein Function unknown 83647456 Nonpathogen - hypothetical protein HCH_04772 1 None None None 83646116 Common - Large exoprotein involved in heme utilization or adhesion HCH_03375 49 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 83643857 Common - hypothetical protein HCH_00980 72 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 83648083 Common - hypothetical protein HCH_05426 11 None None None 83644391 Nonpathogen - hypothetical protein HCH_01543 1 None None None 83643138 Nonpathogen - hypothetical protein HCH_00233 4 None None None 83643418 Common - hypothetical protein HCH_00523 26 None None None 83647387 Nonpathogen - hypothetical protein HCH_04699 2 None None None 83645662 Common - Type II secretory pathway, pullulanase PulA and related Glycosidase HCH_02898 12 None None None 83648322 Nonpathogen - hypothetical protein HCH_05677 1 None None None 83645406 Common - FOG: TPR repeat HCH_02626 6 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83649260 Common - short chain dehydrogenase HCH_06637 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 83649237 Common - uncharacterized protein involved in outer membrane biogenesis HCH_06613 16 None None None 83647215 Common ureF Urease accessory protein UreF HCH_04525 77 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 83648864 Common nusG transcription antitermination protein NusG HCH_06229 215 COG0250 NusG, Transcription antiterminator Transcription 83649235 Common - hypothetical protein HCH_06611 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 83648186 Common - hypothetical protein HCH_05534 18 None None None 83647323 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_04633 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83649078 Nonpathogen - hypothetical protein HCH_06442 1 None None None 83645382 Nonpathogen - hypothetical protein HCH_02600 6 None None None 83648911 Common rpoD RNA polymerase sigma-70 factor RpoD HCH_06274 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 83644400 Common - hypothetical protein HCH_01553 22 COG4850 COG4850, Uncharacterized conserved protein Function unknown 83645319 Common rnhA Ribonuclease HI HCH_02527 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 83646985 Nonpathogen - hypothetical protein HCH_04288 2 None None None 83649538 Nonpathogen - hypothetical protein HCH_06931 2 None None None 83643420 Common - Protein involved in catabolism of external DNA HCH_00525 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 83648113 Common - hypothetical protein HCH_05459 4 None None None 83643141 Common - ABC-type multidrug transport system, ATPase component HCH_00236 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83643871 Common - Glutamate decarboxylase and related PLP-dependent protein HCH_00996 119 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 83645853 Nonpathogen - hypothetical protein HCH_03097 1 None None None 83643321 Common - predicted protein tyrosine phosphatase HCH_00421 21 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 83645140 Common - protein containing tetratricopeptide repeat HCH_02327 11 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83643852 Nonpathogen - hypothetical protein HCH_00975 1 None None None 83646028 Nonpathogen - hypothetical protein HCH_03282 1 None None None 83645748 Nonpathogen - hypothetical protein HCH_02989 1 None None None 83645910 Nonpathogen - hypothetical protein HCH_03157 1 None None None 83644784 Common - Membrane-fusion protein HCH_01961 148 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83649376 Nonpathogen - hypothetical protein HCH_06762 1 None None None 83649329 Nonpathogen - hypothetical protein HCH_06712 1 None None None 83645127 Common - Inosine-uridine nucleoside N-ribohydrolase HCH_02314 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 83648713 Nonpathogen - hypothetical protein HCH_06074 1 None None None 83647199 Common - Rhodanese-related sulfurtransferase HCH_04507 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83649229 Common - TRAP-type C4-dicarboxylate transport system, periplasmic component HCH_06605 99 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83643026 Common - ABC-type phosphate transport system, periplasmic component HCH_00115 131 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 83645218 Common - predicted esterase of the alpha-beta hydrolase superfamily HCH_02419 126 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83646802 Common - predicted sugar phosphatase of the HAD superfamily HCH_04101 94 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 83645427 Common hrpA ATP-dependent helicase HrpA HCH_02648 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 83648772 Common - predicted redox protein, regulator of disulfide bond formation HCH_06134 88 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83649607 Nonpathogen - hypothetical protein HCH_07002 1 None None None 83646916 Common - hypothetical protein HCH_04219 12 None None None 83643212 Nonpathogen - hypothetical protein HCH_00310 2 None None None 83643238 Common - predicted NAD/FAD-binding protein HCH_00336 70 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 83644608 Common trmD tRNA (guanine-N1)-methyltransferase HCH_01774 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 83648173 Common - Zn-dependent Hydrolase, including glyoxylases HCH_05521 25 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83648245 Common - Ketosteroid isomerase-like protein HCH_05596 13 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 83644769 Common - hypothetical protein HCH_01946 13 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 83648728 Nonpathogen - hypothetical protein HCH_06090 1 None None None 83643544 Common thiI thiamine biosynthesis protein ThiI HCH_00653 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 83643620 Common - probable cysteine peptidase, YopT-like HCH_00732 6 None None None 83647965 Common - hypothetical protein HCH_05302 122 COG0327 COG0327, Uncharacterized conserved protein Function unknown 83646021 Nonpathogen - protein containing tetratricopeptide repeat HCH_03274 1 None None None 83649688 Common trmE tRNA modification GTPase TrmE HCH_07086 230 COG0486 ThdF, Predicted GTPase General function prediction only 83645919 Common - Glycine/D-amino acid oxidases (deaminating) HCH_03166 130 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83645102 Common - hypothetical protein HCH_02289 25 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 83643795 Common - hypothetical protein HCH_00916 10 None None None 83647995 Common mreC rod shape-determining protein MreC HCH_05333 142 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 83647594 Common - hypothetical protein HCH_04913 106 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 83643664 Common - Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HCH_00778 152 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83644683 Common - predicted membrane protein HCH_01855 4 COG3308 COG3308, Predicted membrane protein Function unknown 83647733 Common - hypothetical protein HCH_05060 13 COG5626 COG5626, Uncharacterized small conserved protein Function unknown 83644388 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_01540 167 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83646061 Common - MoxR-like ATPase HCH_03316 44 COG0714 COG0714, MoxR-like ATPases General function prediction only 83642964 Common - hypothetical protein HCH_00052 33 None None None 83649244 Common - Zn-dependent Hydrolase, including glyoxylases HCH_06620 47 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83647149 Common hisS histidyl-tRNA synthetase HCH_04455 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83644005 Common - predicted transcriptional regulator HCH_01138 13 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 83649218 Common - SAM-dependent methyltransferase HCH_06592 159 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83646772 Common fliN1 flagellar motor switch protein HCH_04069 118 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83649682 Common - predicted transcriptional regulator HCH_07080 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 83644692 Common pyrG CTP synthetase HCH_01865 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 83647600 Common - predicted thioesterase HCH_04920 140 COG0824 FcbC, Predicted thioesterase General function prediction only 83647238 Common - hypothetical protein HCH_04548 5 None None None 83648137 Nonpathogen - probable monooxygenase HCH_05484 1 COG1359 COG1359, Uncharacterized conserved protein Function unknown 83644887 Common - hypothetical protein HCH_02066 3 None None None 83645505 Common - hypothetical protein HCH_02730 32 None None None 83644394 Nonpathogen - hypothetical protein HCH_01547 3 None None None 83643778 Common sbcD exonuclease subunit SbcD HCH_00897 111 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 83649035 Common amt ammonium transporter HCH_06399 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 83646656 Common - Acetyl/propionyl-CoA carboxylase, alpha subunit HCH_03946 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83642937 Nonpathogen - hypothetical protein HCH_00024 1 None None None 83643395 Nonpathogen - hypothetical protein HCH_00499 1 None None None 83649266 Common - Organic radical activating enzyme HCH_06643 145 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 83645861 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_03105 19 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 83644574 Common - predicted ATPase related to phosphate starvation-inducible protein PhoH HCH_01737 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 83646783 Common flgC1 flagellar basal-body rod protein FlgC HCH_04080 123 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 83647110 Common - Cytochrome c, mono- and diheme variants HCH_04416 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 83643198 Common cyaA adenylate cyclase HCH_00295 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 83644557 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase HCH_01719 195 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83644952 Common - predicted metal-binding protein related to the C-terminal domain of SecA HCH_02133 12 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 83648267 Common - predicted transcriptional regulator HCH_05619 21 COG1396 HipB, Predicted transcriptional regulators Transcription 83643155 Common - Type II secretory pathway, pullulanase PulA and related Glycosidase HCH_00252 118 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 83648662 Nonpathogen - hypothetical protein HCH_06022 1 None None None 83645165 Common tal1 transaldolase B HCH_02352 189 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 83647988 Common mgtE magnesium transporter HCH_05326 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 83646263 Nonpathogen - hypothetical protein HCH_03529 1 None None None 83648669 Common - SAM-dependent methyltransferase HCH_06029 48 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 83648865 Common secE preprotein translocase subunit SecE HCH_06230 16 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 83646701 Nonpathogen - hypothetical protein HCH_03994 1 None None None 83648889 Common - uncharacterized low-complexity protein HCH_06252 13 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 83648922 Common - hypothetical protein HCH_06284 10 None None None 83643529 Common mmsB 3-hydroxyisobutyrate dehydrogenase HCH_00638 166 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 83644354 Nonpathogen - hypothetical protein HCH_01506 1 None None None 83646980 Nonpathogen - hypothetical protein HCH_04283 1 None None None 83643214 Common - hypothetical protein HCH_00312 6 None None None 83643104 Nonpathogen - hypothetical protein HCH_00197 7 None None None 83646654 Common - Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta) HCH_03944 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83648952 Common - Guanylate kinase HCH_06315 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 83648574 Common lspA lipoprotein signal peptidase HCH_05932 187 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83647833 Common - flagellar motor protein MotD HCH_05164 141 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83649107 Common cobI precorrin-2 C20-methyltransferase HCH_06475 98 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 83646840 Nonpathogen - hypothetical protein HCH_04140 1 None None None 83645146 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase HCH_02333 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 83645647 Nonpathogen - hypothetical protein HCH_02882 1 None None None 83643258 Common - predicted extracellular nuclease HCH_00356 51 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 83644813 Nonpathogen - hypothetical protein HCH_01989 1 None None None 83645997 Common - Type III secretory pathway, lipoprotein EscJ HCH_03247 54 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 83648066 Common - Outer membrane phospholipase A HCH_05407 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 83648594 Common nusB transcription antitermination protein NusB HCH_05953 155 COG0781 NusB, Transcription termination factor Transcription 83645283 Nonpathogen - hypothetical protein HCH_02490 1 None None None 83646268 Common - Transcriptional regulator HCH_03535 103 COG1309 AcrR, Transcriptional regulator Transcription 83645990 Common - putative type III secretion protein YscC HCH_03240 131 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 161897902 Common - xanthine-guanine phosphoribosyltransferase HCH_01089 70 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 83645807 Common - predicted protein tyrosine phosphatase HCH_03051 12 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 83648588 Nonpathogen - hypothetical protein HCH_05947 3 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 83649151 Nonpathogen - hypothetical protein HCH_06521 1 None None None 83644892 Common - hypothetical protein HCH_02071 5 None None None 83649662 Common - hypothetical protein HCH_07060 8 None None None 83645152 Common - ATPase with chaperone activity, ATP-binding subunit HCH_02339 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83647739 Nonpathogen - hypothetical protein HCH_05066 1 None None None 83644467 Common gst Glutathione S-transferase HCH_01621 15 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83648106 Nonpathogen - hypothetical protein HCH_05451 1 None None None 83648504 Common xseB exodeoxyribonuclease VII, small subunit HCH_05864 140 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 83647551 Common - Transcriptional regulator HCH_04870 152 COG0583 LysR, Transcriptional regulator Transcription 83647913 Common uppS undecaprenyl diphosphate synthase HCH_05248 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 83647480 Common - Transcriptional regulator HCH_04796 125 COG1609 PurR, Transcriptional regulators Transcription 83646370 Nonpathogen - hypothetical protein HCH_03640 1 None None None 83644313 Common - Membrane-fusion protein HCH_01465 144 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83647142 Nonpathogen - hypothetical protein HCH_04448 1 None None None 83646036 Common - hypothetical protein HCH_03291 2 None None None 83646565 Common - Chemotaxis protein histidine kinase and related kinase HCH_03847 224 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83647383 Nonpathogen - hypothetical protein HCH_04695 1 None None None 83647293 Common - hypothetical protein HCH_04602 21 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83644645 Common - undecaprenyl pyrophosphate phosphatase HCH_01816 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 83646194 Common - ABC-type enterobactin transport system, permease component HCH_03457 191 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 83643491 Common - hypothetical protein HCH_00598 12 None None None 83647131 Common fadE acyl-CoA dehydrogenase HCH_04437 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83644207 Common gpmI phosphoglyceromutase HCH_01352 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 83648208 Nonpathogen - hypothetical protein HCH_05557 1 None None None 83647592 Common - putative Zn-dependent protease, contains TPR repeats HCH_04911 128 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83643024 Common - FOG: HAMP domain HCH_00113 19 COG2770 ResE, FOG: HAMP domain Signal transduction mechanisms 83643157 Nonpathogen - hypothetical protein HCH_00254 1 None None None 83648303 Common - probable phage protein HCH_05656 5 None None None 83647812 Common - Permease of the major facilitator superfamily HCH_05142 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83649116 Nonpathogen - hypothetical protein HCH_06485 1 None None None 83644144 Common - predicted acyltransferase HCH_01285 3 COG2153 ElaA, Predicted acyltransferase General function prediction only 83647747 Common acsA2 acetate--CoA ligase HCH_05074 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 83644312 Nonpathogen - hypothetical protein HCH_01464 1 None None None 83645247 Common cysG Uroporphyrinogen-III methylase HCH_02450 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 83644899 Nonpathogen - hypothetical protein HCH_02078 1 None None None 83646546 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_03825 22 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83644751 Common valS valyl-tRNA synthetase HCH_01928 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83643236 Nonpathogen - hypothetical protein HCH_00334 1 None None None 83645696 Nonpathogen - hypothetical protein HCH_02934 1 None None None 83646169 Nonpathogen - hypothetical protein HCH_03431 1 None None None 83647357 Common - Signal transduction histidine kinase HCH_04668 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 83644066 Nonpathogen - hypothetical protein HCH_01203 1 None None None 83646800 Common - Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) HCH_04099 36 None None None 83645380 Nonpathogen - hypothetical protein HCH_02598 4 None None None 83645065 Nonpathogen - hypothetical protein HCH_02249 1 None None None 83648813 Nonpathogen - hypothetical protein HCH_06178 2 None None None 83644236 Common - Rhs family protein HCH_01383 68 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83649428 Common - short-chain alcohol dehydrogenase-like protein HCH_06815 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83649089 Common - hypothetical protein HCH_06455 15 None None None 83643453 Common - hypothetical protein HCH_00559 4 None None None 83647197 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_04505 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83648048 Common - hypothetical protein HCH_05389 220 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 83643785 Nonpathogen - hypothetical protein HCH_00904 1 None None None 83646488 Nonpathogen - hypothetical protein HCH_03766 1 None None None 83644545 Common dksA DnaK suppressor protein HCH_01707 136 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 83646457 Common - probable glycosyl hydrolase HCH_03733 12 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 83647105 Common - Cytochrome c, mono- and diheme variants HCH_04411 36 None None None 83649602 Common - hypothetical protein HCH_06997 32 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 83646402 Nonpathogen - hypothetical protein HCH_03672 1 None None None 83647956 Common - uncharacterized FlgJ-related protein HCH_05292 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 83643818 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_00939 48 COG0456 RimI, Acetyltransferases General function prediction only 83646102 Nonpathogen - hypothetical protein HCH_03358 1 None None None 83649677 Common atpF2 F0F1 ATP synthase subunit B HCH_07076 94 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 83646160 Nonpathogen - hypothetical protein HCH_03422 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83643962 Common allA ureidoglycolate hydrolase HCH_01092 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 83644518 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_01675 77 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83647938 Common - Glycosyltransferase involved in cell wall biogenesis HCH_05273 80 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83646507 Common - Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit HCH_03785 228 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 83648629 Common - predicted signal transduction protein HCH_05989 62 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83647371 Common ugd UDP-glucose dehydrogenase HCH_04682 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 83644538 Common - Transcriptional regulator HCH_01700 141 COG0583 LysR, Transcriptional regulator Transcription 83644276 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_01424 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83644949 Common ispZ intracellular septation protein A HCH_02130 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 83643435 Common - Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain HCH_00540 142 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83645520 Common - Glycosyltransferase, probably involved in cell wall biogenesis HCH_02745 113 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83648397 Common - Superfamily II DNA and RNA helicase HCH_05756 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83647009 Common - uncharacterized NAD(FAD)-dependent dehydrogenase HCH_04312 117 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 83644612 Common - aminotransferase HCH_01778 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83644266 Common sufC FeS assembly ATPase SufC HCH_01414 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 83646937 Common - uncharacterized protein with a C-terminal OMP (outer membrane protein) domain HCH_04240 33 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 83643002 Common - group II intron-encoding maturase HCH_00091 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83643060 Common - FOG: CBS domain HCH_00151 140 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 83646415 Common - 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit HCH_03686 210 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 83643999 Common - ABC-type oligopeptide transport system, ATPase component HCH_01131 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83643270 Nonpathogen - hypothetical protein HCH_00369 1 None None None 83648276 Common - hypothetical protein HCH_05628 19 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 83646006 Nonpathogen - hypothetical protein HCH_03257 1 None None None 83643838 Common btuB Outer membrane cobalamin receptor protein HCH_00960 118 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 83646826 Nonpathogen - hypothetical protein HCH_04126 1 None None None 83644962 Common plsX Fatty acid/phospholipid biosynthesis enzyme HCH_02142 176 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 83645529 Common - hypothetical protein HCH_02754 10 None None None 83645974 Common - hypothetical protein HCH_03223 19 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 83647093 Nonpathogen - hypothetical protein HCH_04398 2 None None None 83648663 Nonpathogen - Permease of the major facilitator superfamily HCH_06023 2 None None None 83648806 Nonpathogen - hypothetical protein HCH_06171 1 None None None 83649099 Common bchI magnesium chelatase ATPase subunit I HCH_06466 100 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 83648738 Common - uncharacterized small membrane protein HCH_06100 7 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 83643947 Common tatA Sec-independent protein secretion pathway components HCH_01076 54 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 83647484 Nonpathogen - hypothetical protein HCH_04800 1 None None None 83644441 Common htpG1 Molecular chaperone, HSP90 family HCH_01594 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 83643992 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01124 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646518 Common - predicted membrane protein HCH_03796 61 COG2259 COG2259, Predicted membrane protein Function unknown 83647270 Common rpmI 50S ribosomal protein L35 HCH_04578 34 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 83647428 Common sucD Succinyl-CoA synthetase, alpha subunit HCH_04740 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 83647434 Common sdhA succinate dehydrogenase flavoprotein subunit HCH_04747 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 83647677 Common - Secreted/periplasmic Zn-dependent peptidase, insulinase-like HCH_05001 199 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 83647040 Nonpathogen - hypothetical protein HCH_04344 4 None None None 83646245 Nonpathogen - hypothetical protein HCH_03509 1 None None None 83648762 Common - (acyl-carrier-protein) S-malonyltransferase HCH_06124 72 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 83646583 Common - hypothetical protein HCH_03866 4 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 83649482 Common acnA aconitate hydratase 1 HCH_06874 222 COG1048 AcnA, Aconitase A Energy production and conversion 83646533 Nonpathogen - hypothetical protein HCH_03812 1 None None None 83644381 Common metK S-adenosylmethionine synthetase HCH_01533 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 83645639 Nonpathogen - hypothetical protein HCH_02873 1 None None None 83644855 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02031 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83645455 Common - Transcriptional regulator HCH_02677 78 COG1309 AcrR, Transcriptional regulator Transcription 83646467 Nonpathogen - hypothetical protein HCH_03743 1 None None None 83649640 Nonpathogen - hypothetical protein HCH_07035 1 None None None 83648339 Nonpathogen - hypothetical protein HCH_05693 3 None None None 83644256 Nonpathogen - hypothetical protein HCH_01403 1 None None None 83644968 Common tmk thymidylate kinase HCH_02148 224 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 83648237 Common - FOG: WD40 repeat HCH_05588 30 COG2319 COG2319, FOG: WD40 repeat General function prediction only 83648945 Common - predicted signal transduction protein HCH_06308 59 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83645299 Common - putative chaperone HCH_02507 128 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83647170 Common flgH2 Flagellar basal body L-ring protein HCH_04476 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 83645934 Common - Serine/threonine protein kinase HCH_03181 149 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83644475 Nonpathogen - hypothetical protein HCH_01629 1 None None None 83646667 Common - Retron-type reverse transcriptase HCH_03958 58 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83646990 Nonpathogen - hypothetical protein HCH_04293 1 None None None 83648784 Nonpathogen - hypothetical protein HCH_06147 1 None None None 83643461 Common mutM1 formamidopyrimidine-DNA glycosylase HCH_00567 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 83646498 Nonpathogen - hypothetical protein HCH_03776 1 None None None 83645234 Common trpA1 tryptophan synthase, alpha subunit HCH_02437 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 83644087 Common dnaJ DnaJ-class molecular chaperone with C-terminal Zn finger domain HCH_01225 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83649252 Nonpathogen - probable two component response regulator protein containing GerE domain HCH_06628 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83644128 Common - Fe-S oxidoreductase HCH_01270 164 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 83643306 Common - Integrase HCH_00405 142 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83645630 Nonpathogen - hypothetical protein HCH_02863 1 None None None 83647697 Nonpathogen - hypothetical protein HCH_05022 1 None None None 83647065 Common ccmA heme exporter protein CcmA HCH_04369 180 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 83644804 Common - Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzyme HCH_01981 214 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 83645240 Common metZ O-succinylhomoserine sulfhydrylase HCH_02443 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 83648028 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_05369 48 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83649247 Common - Anti-sigma factor HCH_06623 29 COG3806 ChrR, Transcriptional activator Transcription 83648622 Common - hypothetical protein HCH_05981 49 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 83643135 Common - Signal transduction histidine kinase regulating C4-dicarboxylate transport system HCH_00230 218 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83647842 Common flhA flagellar biosynthesis protein A HCH_05174 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 83648125 Common - hypothetical protein HCH_05472 6 None None None 83648794 Common - putative sulfotransferase protein HCH_06158 29 None None None 83642940 Common trkA potassium transporter peripheral membrane component HCH_00027 152 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 83644746 Common - Membrane protein required for beta-lactamase induction HCH_01922 28 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 83646094 Common - predicted periplasmic or secreted lipoprotein HCH_03350 22 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 83646367 Nonpathogen - hypothetical protein HCH_03637 1 None None None 83645109 Common - heat shock protein HtpX HCH_02296 194 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 83647184 Common - ABC-type multidrug transport system, ATPase component HCH_04491 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83646779 Common fliH1 putative flagellar assembly protein HCH_04076 23 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83647779 Common yscO putative type III secretion protein YscO HCH_05108 6 None None None 83645845 Common - Transcriptional regulator HCH_03089 121 COG2188 PhnF, Transcriptional regulators Transcription 83643560 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00670 20 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645463 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A HCH_02685 40 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 83645263 Common - Transcriptional regulator HCH_02466 130 COG1609 PurR, Transcriptional regulators Transcription 83644907 Nonpathogen - hypothetical protein HCH_02087 1 None None None 83647061 Common ccmE Cytochrome c-type biogenesis protein CcmE HCH_04365 97 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 83647856 Nonpathogen - hypothetical protein HCH_05188 1 None None None 83648679 Nonpathogen - hypothetical protein HCH_06039 2 None None None 83645959 Nonpathogen - hypothetical protein HCH_03208 1 None None None 83645034 Common - Cation/multidrug efflux pump HCH_02216 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83644422 Common - Transcription elongation factor HCH_01575 15 COG0782 GreA, Transcription elongation factor Transcription 83643263 Common - uncharacterized low-complexity protein HCH_00361 29 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 83644905 Common - hypothetical protein HCH_02084 4 None None None 83648050 Common - oligoribonuclease HCH_05390 89 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 83648653 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_06013 203 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83643059 Common - predicted thioesterase HCH_00150 33 COG0824 FcbC, Predicted thioesterase General function prediction only 83643766 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_00884 160 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83647150 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase HCH_04456 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 83646606 Nonpathogen - hypothetical protein HCH_03890 1 None None None 83643093 Common - hypothetical protein HCH_00186 31 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 83649571 Common acoR Transcriptional activator of acetoin/glycerol metabolism HCH_06966 172 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 83645683 Common - hypothetical protein HCH_02919 3 None None None 83648937 Common - Methyl-accepting chemotaxis protein HCH_06300 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643314 Common - predicted protein-tyrosine phosphatase HCH_00414 37 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 83647798 Nonpathogen - hypothetical protein HCH_05128 1 None None None 83643405 Common - predicted transcriptional regulator HCH_00508 147 COG0640 ArsR, Predicted transcriptional regulators Transcription 83645511 Nonpathogen - hypothetical protein HCH_02735 1 None None None 83647289 Common gloA2 lactoylglutathione lyase HCH_04598 138 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83643348 Common - FOG: CheY-like receiver HCH_00448 5 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643696 Common nfi Deoxyinosine 3'endonuclease (endonuclease V) HCH_00812 26 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 83643599 Common - hypothetical protein HCH_00711 5 COG2267 PldB, Lysophospholipase Lipid metabolism 83644106 Common - Hydrolase of the alpha/beta superfamily HCH_01245 80 COG2267 PldB, Lysophospholipase Lipid metabolism 83644177 Common - predicted phosphohydrolase HCH_01319 14 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83649636 Nonpathogen - hypothetical protein HCH_07031 1 None None None 83643865 Common - hypothetical protein HCH_00989 6 None None None 83646158 Nonpathogen - hypothetical protein HCH_03420 2 None None None 83644844 Common - predicted transcriptional regulator HCH_02020 92 COG2378 COG2378, Predicted transcriptional regulator Transcription 83643032 Nonpathogen - hypothetical protein HCH_00122 1 None None None 83648731 Nonpathogen - hypothetical protein HCH_06093 10 None None None 83649410 Common - Transcriptional regulator HCH_06796 88 COG1309 AcrR, Transcriptional regulator Transcription 83646712 Common - FOG: Ankyrin repeat HCH_04005 5 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 83649145 Nonpathogen - hypothetical protein HCH_06515 1 None None None 83649257 Common - short chain dehydrogenase HCH_06633 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83642989 Nonpathogen - hypothetical protein HCH_00078 1 None None None 83647002 Common - FOG: CheY-like receiver HCH_04305 109 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 83648324 Common - hypothetical protein HCH_05679 4 None None None 83648512 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein HCH_05872 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 83645765 Common - hypothetical protein HCH_03007 15 None None None 83647037 Common - hypothetical protein HCH_04341 8 None None None 83649227 Common - Glutathionylspermidine synthase HCH_06602 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 83649404 Common - Membrane carboxypeptidase (penicillin-binding protein) HCH_06790 15 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 83649435 Common - Large exoprotein involved in heme utilization or adhesion HCH_06822 9 None None None 83646932 Nonpathogen - hypothetical protein HCH_04235 1 None None None 83646219 Common - Permease of the major facilitator superfamily HCH_03483 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83646365 Nonpathogen - hypothetical protein HCH_03635 1 None None None 83646550 Common - Transcriptional regulator HCH_03832 182 COG0583 LysR, Transcriptional regulator Transcription 83648976 Common pyrE orotate phosphoribosyltransferase HCH_06340 146 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 83647450 Common - hypothetical protein HCH_04765 29 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 83643613 Nonpathogen - hypothetical protein HCH_00725 3 None None None 83648472 Common - Chemotaxis protein histidine kinase and related kinase HCH_05832 224 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83647684 Common - protein containing LysM domain HCH_05009 20 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 83644451 Common tpx Peroxiredoxin HCH_01604 128 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83644170 Common trx2 thioredoxin HCH_01313 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 83645779 Nonpathogen - hypothetical protein HCH_03023 1 None None None 83649373 Nonpathogen - hypothetical protein HCH_06757 1 None None None 83647582 Common - Carbonic anhydrase HCH_04901 120 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 83647721 Nonpathogen - hypothetical protein HCH_05048 2 None None None 83646282 Nonpathogen - hypothetical protein HCH_03550 1 None None None 83646437 Common - Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) HCH_03710 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 83646142 Nonpathogen - hypothetical protein HCH_03402 1 None None None 83644999 Nonpathogen - hypothetical protein HCH_02181 1 None None None 83643275 Common - hypothetical protein HCH_00374 11 None None None 83646972 Common - TRAP-type mannitol/chloroaromatic compound transport system, large permease component HCH_04275 127 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 83646074 Nonpathogen - hypothetical protein HCH_03330 2 None None None 83644796 Nonpathogen - hypothetical protein HCH_01973 1 None None None 83643366 Common - predicted phosphohydrolase HCH_00466 12 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83643243 Nonpathogen - hypothetical protein HCH_00341 1 None None None 83643649 Common - hypothetical protein HCH_00762 33 COG2606 EbsC, Uncharacterized conserved protein Function unknown 83642935 Common glyQ glycyl-tRNA synthetase subunit alpha HCH_00022 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 83649411 Common pilE Tfp pilus assembly protein, major pilin PilA HCH_06797 18 COG2314 XynA, Predicted membrane protein Function unknown 83647947 Common - hypothetical protein HCH_05283 17 None None None 83647775 Nonpathogen - hypothetical protein HCH_05104 1 None None None 83648365 Nonpathogen - hypothetical protein HCH_05720 1 None None None 83646410 Common - Co/Zn/Cd efflux system component HCH_03680 65 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 83647304 Common groEL chaperonin GroEL HCH_04613 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 83643638 Common - ABC-type uncharacterized transport system, permease component HCH_00751 222 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 83645577 Nonpathogen - hypothetical protein HCH_02809 3 None None None 83649066 Common - N-methylhydantoinase A/acetone carboxylase, beta subunit HCH_06431 118 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83647453 Common - predicted nucleoside-diphosphate sugar epimerase HCH_04768 112 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 83644970 Common miaE Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA HCH_02150 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 83644431 Common - hypothetical protein HCH_01584 80 COG2013 COG2013, Uncharacterized conserved protein Function unknown 83645198 Common - Glycosyltransferase HCH_02396 210 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83645756 Nonpathogen - hypothetical protein HCH_02998 1 None None None 83644910 Common - Rhs family protein HCH_02090 10 None None None 83644094 Common ftsH ATP-dependent Zn protease HCH_01232 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 83644191 Common - hypothetical protein HCH_01334 3 None None None 83649004 Nonpathogen - hypothetical protein HCH_06369 1 None None None 83647394 Common - ATP-dependent RNA helicase DbpA HCH_04706 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83644818 Nonpathogen - hypothetical protein HCH_01994 1 None None None 83647875 Common alaS alanyl-tRNA synthetase HCH_05209 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83647918 Common map2 methionine aminopeptidase, type I HCH_05254 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 83644301 Nonpathogen - hypothetical protein HCH_01451 1 None None None 83644831 Common - Transcriptional regulator HCH_02007 121 COG0583 LysR, Transcriptional regulator Transcription 83647507 Nonpathogen - FOG: TPR repeat HCH_04823 5 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83642947 Common hemF coproporphyrinogen III oxidase HCH_00036 112 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 83649393 Common - probable phage protein HCH_06779 10 None None None 83648874 Common - hypothetical protein HCH_10035 6 None None None 83646331 Common - Cytochrome P450 HCH_03601 33 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 83647823 Nonpathogen - hypothetical protein HCH_05153 1 None None None 83648996 Common - hypothetical protein HCH_06361 13 None None None 83648749 Common - hypothetical protein HCH_06110 5 COG4874 COG4874, Uncharacterized protein conserved in bacteria containing a pentein-type domain Function unknown 83644714 Common nth endonuclease III HCH_01887 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 83647878 Common - predicted membrane protein/domain HCH_05212 29 COG1714 COG1714, Predicted membrane protein/domain Function unknown 83646424 Common - Transcriptional regulator HCH_03697 134 COG0583 LysR, Transcriptional regulator Transcription 83644523 Nonpathogen - hypothetical protein HCH_01682 1 None None None 83643517 Common - FOG: Ankyrin repeat HCH_00625 92 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 83646575 Common gcvT glycine cleavage system T protein HCH_03858 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 83643343 Nonpathogen - hypothetical protein HCH_00443 1 None None None 83644674 Common - 2,3-diketo-5-methylthio-1-phosphopentane phosphatase HCH_01846 31 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 83646726 Common - Nitrate/nitrite transporter HCH_04020 80 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 83645181 Common clpP2 ATP-dependent Clp protease, proteolytic subunit ClpP HCH_02373 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83645708 Common - ABC-type Mn2+/Zn2+ transport system, permease components HCH_02946 16 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83646744 Common - hypothetical protein HCH_04039 16 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 83644686 Nonpathogen - hypothetical protein HCH_01859 1 None None None 83646236 Common - NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain HCH_03500 124 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 83644004 Common - Chitinase HCH_01137 55 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 83645256 Common - HD-GYP domain HCH_02459 125 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 83649199 Common - ABC-type Fe3+-siderophore transport system, permease component HCH_06572 147 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83643506 Nonpathogen - hypothetical protein HCH_00614 1 None None None 83646642 Common gspJ general secretion pathway protein J HCH_03931 24 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 83647968 Common - Histidinol dehydrogenase HCH_05305 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 83645389 Common - hypothetical protein HCH_02607 13 None None None 83644147 Common pbpG D-alanyl-D-alanine carboxypeptidase HCH_01289 151 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 83644075 Common - ABC-type antimicrobial peptide transport system, permease component HCH_01212 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83645829 Common corA magnesium and cobalt transport protein CorA HCH_03073 154 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 83645599 Nonpathogen - hypothetical protein HCH_02831 1 None None None 83646445 Common - hypothetical protein HCH_03719 5 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 83644729 Common - hypothetical protein HCH_01904 20 None None None 83646224 Common - (acyl-carrier-protein) S-malonyltransferase HCH_03488 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 83644738 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase HCH_01913 34 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83645558 Nonpathogen - hypothetical protein HCH_02788 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 83646377 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_03647 224 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645081 Common - predicted transcriptional regulator HCH_02265 54 COG1959 COG1959, Predicted transcriptional regulator Transcription 83648565 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_05925 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83647266 Common ihfA integration host factor subunit alpha HCH_04573 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83646283 Nonpathogen - hypothetical protein HCH_03551 1 None None None 83645496 Common - hypothetical protein HCH_02721 28 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 83647882 Common - ABC-type arginine/histidine transport system, permease component HCH_05216 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 83648078 Nonpathogen - hypothetical protein HCH_05420 4 None None None 83648383 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_05740 210 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83648934 Common - hypothetical protein HCH_06297 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 83646168 Nonpathogen - hypothetical protein HCH_03430 10 None None None 83646238 Common - FOG: GGDEF domain HCH_03502 93 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643827 Nonpathogen - hypothetical protein HCH_00949 1 None None None 83646528 Nonpathogen - hypothetical protein HCH_03807 1 None None None 83647512 Common - flagellin modification protein A HCH_04828 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83646231 Common - predicted transcriptional regulator HCH_03495 151 COG1733 COG1733, Predicted transcriptional regulators Transcription 83644167 Common - Outer membrane receptor protein, mostly Fe transport HCH_01310 87 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 83647179 Nonpathogen - hypothetical protein HCH_04486 1 None None None 83644915 Common - Rhs family protein HCH_02095 36 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83648578 Nonpathogen - hypothetical protein HCH_05936 1 None None None 83646647 Common gspE Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_03937 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 83644555 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_01717 140 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83643049 Common thiG thiazole synthase HCH_00140 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 83646200 Common - Lhr-like helicase HCH_03463 235 COG1201 Lhr, Lhr-like helicases General function prediction only 83644566 Common - FOG: TPR repeat HCH_01729 133 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83649354 Nonpathogen - hypothetical protein HCH_06739 1 None None None 83647568 Common - Serine/threonine protein kinase HCH_04887 156 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83646977 Common - hypothetical protein HCH_04280 22 COG5351 COG5351, Uncharacterized protein conserved in bacteria Function unknown 83642976 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_00064 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83645374 Nonpathogen - hypothetical protein HCH_02592 8 None None None 83644693 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase HCH_01866 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 83644491 Common - FAD/FMN-containing dehydrogenase HCH_01647 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83646960 Common - hypothetical protein HCH_04263 18 None None None 83644760 Common - ABC-type branched-chain amino acid transport system, periplasmic component HCH_01937 97 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83646631 Nonpathogen - hypothetical protein HCH_03920 1 None None None 83644018 Nonpathogen - hypothetical protein HCH_01151 1 None None None 83647504 Common fliC Flagellin and related hook-associated protein HCH_04820 124 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83649049 Common - Glutathione S-transferase HCH_06414 93 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83643127 Common recD exodeoxyribonuclease V, alpha subunit HCH_00222 124 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 83648534 Common - predicted endonuclease distantly related to archaeal Holliday junction resolvase HCH_05895 161 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 83648913 Common - hypothetical protein HCH_06275 2 None None None 83643331 Common pyk pyruvate kinase HCH_00431 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 83648085 Common - predicted exporters of the RND superfamily HCH_05429 58 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 83646846 Common - patatin-like phospholipase family protein HCH_04146 20 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83647127 Common - Restriction endonuclease HCH_04433 88 COG1403 McrA, Restriction endonuclease Defense mechanisms 83643985 Common - predicted transcriptional regulator HCH_01117 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 83643074 Nonpathogen - hypothetical protein HCH_00165 1 None None None 83643374 Nonpathogen - hypothetical protein HCH_00475 5 None None None 83643917 Common ilvE1 branched-chain amino acid aminotransferase HCH_01045 218 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83645814 Common - Nucleoside-diphosphate-sugar epimerase HCH_03058 103 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83646042 Common - ABC-type sugar transport system, permease components HCH_03297 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83648635 Nonpathogen - hypothetical protein HCH_05995 1 None None None 83644720 Common rnfA predicted NADH:ubiquinone oxidoreductase, subunit RnfA HCH_01895 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 83648696 Common - hypothetical protein HCH_06056 21 None None None 83645086 Common - hypothetical protein HCH_02271 26 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 83648536 Common sspB ClpXP protease specificity-enhancing factor HCH_10003 65 COG2969 SspB, Stringent starvation protein B General function prediction only 83646476 Common - ABC-type amino acid transport system, permease component HCH_03754 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83647013 Nonpathogen - hypothetical protein HCH_04316 1 None None None 83646312 Nonpathogen - probable zinc metallopeptidase HCH_03580 4 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 83643426 Nonpathogen - hypothetical protein HCH_00530 1 None None None 83643820 Common - protein containing VWFA domain HCH_00942 15 None None None 83645070 Common - predicted phosphatase HCH_02254 17 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 83645302 Common - Sulfate permease and related transporters (MFS superfamily) HCH_02510 167 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 83643975 Common - hydroxydechloroatrazine ethylaminohydrolase HCH_01106 172 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83646250 Common - Cation/multidrug efflux pump HCH_03514 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83646847 Common - hypothetical protein HCH_04147 14 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83647235 Common - hypothetical protein HCH_04545 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83647056 Common - hypothetical protein HCH_04360 22 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 83647348 Common - Methyl-accepting chemotaxis protein HCH_04659 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648455 Nonpathogen - hypothetical protein HCH_05814 1 None None None 83645943 Common - Microcystin-dependent protein HCH_03190 34 COG4675 MdpB, Microcystin-dependent protein Function unknown 83649171 Nonpathogen - hypothetical protein HCH_06542 1 None None None 83648170 Nonpathogen - hypothetical protein HCH_05518 1 None None None 83647157 Common cysE serine O-acetyltransferase HCH_04463 211 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83644160 Common - Transcriptional regulator HCH_01304 111 COG0583 LysR, Transcriptional regulator Transcription 83647861 Common fliF flagellar MS-ring protein HCH_05194 124 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 83649596 Nonpathogen - hypothetical protein HCH_06990 1 None None None 83647210 Common ureD Urease accessory protein UreH HCH_04520 74 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 83646243 Nonpathogen - hypothetical protein HCH_03507 1 None None None 83642982 Common - ABC-type sugar transport system, periplasmic component HCH_00071 73 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83643487 Common - hypothetical protein HCH_00594 5 None None None 83646186 Common - (acyl-carrier-protein) S-malonyltransferase HCH_03449 205 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 83648606 Common gltB glutamate synthase subunit alpha HCH_05965 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 83644404 Common polB DNA polymerase II HCH_01557 64 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 83646508 Common - hypothetical protein HCH_03786 3 None None None 83648682 Common - Signal transduction histidine kinase HCH_06042 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83648224 Common - Arylamine N-acetyltransferase HCH_05574 43 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 83643862 Common - hypothetical protein HCH_00985 6 None None None 83645822 Common - Transcriptional regulator HCH_03066 130 COG0583 LysR, Transcriptional regulator Transcription 83645710 Nonpathogen - hypothetical protein HCH_02948 1 None None None 83643334 Common glk glucokinase HCH_00434 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 83649498 Common - hypothetical protein HCH_06890 40 None None None 83646356 Nonpathogen - hypothetical protein HCH_03625 1 None None None 83647566 Common - Multimeric flavodoxin WrbA HCH_04885 27 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 83649434 Nonpathogen - hypothetical protein HCH_06821 1 None None None 83643054 Nonpathogen - hypothetical protein HCH_00145 1 None None None 83645296 Common - Nucleoside-diphosphate-sugar epimerase HCH_02504 100 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83645446 Common - uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) HCH_02668 45 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 83643118 Common - predicted carbamoyl transferase, NodU family HCH_00212 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 83647712 Common - endonuclease/exonuclease/phophatase family protein HCH_05039 10 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 83645516 Common - hypothetical protein HCH_02741 27 None None None 83643908 Common glnA glutamine synthetase, type I HCH_01036 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83644868 Common tag 3-methyladenine DNA glycosylase HCH_02047 133 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 83646967 Common - FOG: EAL domain HCH_04270 224 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83649015 Nonpathogen - hypothetical protein HCH_06380 1 None None None 83645760 Common - predicted esterase of the alpha/beta hydrolase fold HCH_03002 53 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 83645414 Common - Antitoxin of toxin-antitoxin stability system HCH_02635 8 None None None 83646058 Common - Transposase and inactivated derivatives HCH_03313 6 None None None 83648195 Common - Alpha-tubulin suppressor and related RCC1 domain-containing protein HCH_05544 32 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 83643282 Common - probable phage protein HCH_00381 10 None None None 83644202 Common hisF imidazole glycerol phosphate synthase subunit HisF HCH_01347 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 83645546 Nonpathogen - hypothetical protein HCH_02773 1 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83649253 Common - NADH dehydrogenase, FAD-containing subunit HCH_06629 163 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 83647240 Common - bacteriophage TP901-1 ORF40-like protein HCH_04550 3 None None None 83647645 Common pyrD dihydroorotate dehydrogenase HCH_04965 230 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 83646617 Common - FOG: Ankyrin repeat HCH_03903 70 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 83649605 Common - ADP-ribosylglycohydrolase HCH_07000 83 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 83644035 Common - Ribose/xylose/arabinose/galactoside ABC-type transport system, permease components HCH_01169 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83645794 Common - hypothetical protein HCH_03038 83 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 83644154 Common - ABC-type sugar transport system, ATPase components HCH_01297 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83644442 Common - hypothetical protein HCH_01595 5 None None None 83643956 Common - Non-ribosomal peptide synthetase modules and related protein HCH_01086 28 None None None 83644496 Common - hypothetical protein HCH_01652 45 COG2128 COG2128, Uncharacterized conserved protein Function unknown 83648277 Nonpathogen - hypothetical protein HCH_05629 1 None None None 83647718 Common - Non-ribosomal peptide synthetase modules and related protein HCH_05045 207 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648120 Nonpathogen - hypothetical protein HCH_05465 1 None None None 83646326 Common - hypothetical protein HCH_03595 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 83647458 Common - Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains) HCH_04774 113 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 83649509 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_06901 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83648015 Common - predicted metalloendopeptidase HCH_05353 18 None None None 83645769 Common - 5-carboxymethyl-2-hydroxymuconate isomerase HCH_03011 35 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 83643111 Common - probable alpha-glucosidase HCH_00205 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83646633 Common - Outer membrane receptor protein, mostly Fe transport HCH_03922 114 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 83648387 Common - Transcriptional regulator HCH_05743 126 COG1309 AcrR, Transcriptional regulator Transcription 83644036 Common - ABC-type sugar transport system, periplasmic component HCH_01170 83 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83644861 Nonpathogen - hypothetical protein HCH_02037 1 None None None 83645379 Common - Thiol-disulfide isomerase and thioredoxins HCH_02597 211 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83646822 Nonpathogen - hypothetical protein HCH_04122 1 None None None 83643675 Common - predicted phosphohydrolase (DHH superfamily) HCH_00790 13 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 83645419 Nonpathogen - hypothetical protein HCH_02640 1 None None None 83646677 Nonpathogen - hypothetical protein HCH_03968 1 None None None 83643144 Common selD selenide, water dikinase HCH_00239 124 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 83645275 Nonpathogen - Ferredoxin HCH_02480 6 COG0633 Fdx, Ferredoxin Energy production and conversion 83648340 Nonpathogen - hypothetical protein HCH_05694 2 None None None 83649619 Nonpathogen - hypothetical protein HCH_07015 2 None None None 83646688 Common - hypothetical protein HCH_03979 28 COG4704 COG4704, Uncharacterized protein conserved in bacteria Function unknown 83646592 Nonpathogen - hypothetical protein HCH_03875 1 None None None 83645917 Common - Pectate lyase HCH_03164 22 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 83643287 Common - hypothetical protein HCH_00386 5 None None None 83644875 Common - uncharacterized enzyme related to aldose 1-epimerase HCH_02054 54 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 83647931 Common - hypothetical protein HCH_05268 5 None None None 83643247 Common lamB maltoporin HCH_00345 27 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 83645775 Common - Outer membrane protein HCH_03018 50 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83646065 Common - hypothetical protein HCH_03320 64 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83646874 Common - predicted transcriptional regulator HCH_04177 117 COG0640 ArsR, Predicted transcriptional regulators Transcription 83649042 Common - Glycosidase HCH_06407 160 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83645620 Nonpathogen - hypothetical protein HCH_02853 1 None None None 83648022 Common - Acyl-CoA dehydrogenase HCH_05360 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83648487 Common - Gamma-glutamyl phosphate reductase HCH_05847 193 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 83647391 Nonpathogen - hypothetical protein HCH_04702 1 None None None 83648880 Common - Integral membrane protein CcmA involved in cell shape determination HCH_06243 60 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 83647628 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_04949 36 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83648834 Common rpmD ribosomal protein L30 HCH_10027 133 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 83643106 Common - probable alpha-glucosidase HCH_00199 160 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83648855 Common fusA1 translation elongation factor G HCH_06220 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 83647365 Nonpathogen - hypothetical protein HCH_04676 1 None None None 83649282 Common - Signal transduction histidine kinase HCH_06659 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647963 Common - predicted ATPase HCH_05300 104 COG1485 COG1485, Predicted ATPase General function prediction only 83645285 Common - hypothetical protein HCH_02491 10 None None None 83648888 Common - hypothetical protein HCH_06251 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 83643167 Common - hypothetical protein HCH_00264 4 None None None 83645783 Common - uncharacterized protein conserved in bacteria, putative lipoprotein HCH_03028 24 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 83648283 Common istA2 transposase, IS21 family HCH_05635 74 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 83647088 Common - hypothetical protein HCH_04393 5 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83647599 Common - Biopolymer transport protein HCH_04919 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 83645541 Common - probable exopolysaccharide synthesis protein HCH_02767 12 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 83648614 Common pilM Tfp pilus assembly protein, ATPase PilM HCH_05972 93 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 83649268 Common - Anaerobic dehydrogenase, typically selenocysteine-containing HCH_06645 179 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 83645954 Common - predicted transcriptional regulator HCH_03203 82 COG0640 ArsR, Predicted transcriptional regulators Transcription 83643791 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00910 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644250 Common - hypothetical protein HCH_01397 6 None None None 83645622 Common - Site-specific DNA methylase HCH_02855 67 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 83649025 Nonpathogen - hypothetical protein HCH_06390 1 None None None 83648715 Common - N-acyl-D-glucosamine 2-epimerase HCH_06076 46 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 83647167 Common flgK Flagellar hook-associated protein HCH_04473 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 83643051 Nonpathogen - hypothetical protein HCH_00142 1 None None None 83645551 Common - FOG: GGDEF domain HCH_02781 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643496 Common - Transposase and inactivated derivatives HCH_00603 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643867 Common - ATPase involved in DNA repair HCH_00992 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83646114 Nonpathogen - hypothetical protein HCH_03373 12 None None None 83647665 Common purU formyltetrahydrofolate deformylase HCH_04985 224 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 83647688 Common - Zinc carboxypeptidase-related protein HCH_05013 18 COG3608 COG3608, Predicted deacylase General function prediction only 83649594 Nonpathogen - hypothetical protein HCH_06989 1 None None None 83644882 Common rluA1 Pseudouridylate synthases, 23S RNA-specific HCH_02061 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83643903 Common - predicted aminopeptidase HCH_01031 16 COG4324 COG4324, Predicted aminopeptidase General function prediction only 83646781 Common fliF1 flagellar M-ring protein FliF HCH_04078 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 83646304 Common - protein containing BNR/Asp-box repeats HCH_03572 19 None None None 83646172 Nonpathogen - hypothetical protein HCH_03434 9 None None None 83643466 Common - predicted ATPase involved in cell division HCH_00573 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 83647437 Common gltA citrate synthase I HCH_04750 194 COG0372 GltA, Citrate synthase Energy production and conversion 83643160 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_00257 139 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83643204 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00302 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643723 Common - Signal transduction histidine kinase, glucose-6-phosphate specific HCH_00840 147 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 83647421 Common - Transcriptional regulator HCH_04733 49 COG1802 GntR, Transcriptional regulators Transcription 83649505 Nonpathogen - hypothetical protein HCH_06897 1 None None None 83649225 Common - predicted membrane protein HCH_06600 27 COG3766 COG3766, Predicted membrane protein Function unknown 83643652 Common - predicted methyltransferase HCH_00765 28 COG3897 COG3897, Predicted methyltransferase General function prediction only 83648062 Common serB phosphoserine phosphatase SerB HCH_05403 167 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 83645719 Common - Fe-S oxidoreductase HCH_02958 149 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 83646520 Nonpathogen - hypothetical protein HCH_03799 1 None None None 83646672 Common - hypothetical protein HCH_03963 4 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 83646796 Nonpathogen - hypothetical protein HCH_04094 1 None None None 83646051 Nonpathogen - protein of unknown function (DUF1555) HCH_03306 14 None None None 83648907 Common - Metal-dependent protease with possible chaperone activity HCH_06270 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 83646835 Common - ADP-ribosylglycohydrolase HCH_04135 16 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 83644285 Common - FOG: TPR repeat HCH_01434 16 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 83647610 Common - Signal transduction histidine kinase HCH_04931 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 161897896 Common clpS ATP-dependent Clp protease adaptor protein ClpS HCH_02338 120 COG2127 COG2127, Uncharacterized conserved protein Function unknown 83647605 Common - hypothetical protein HCH_04926 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 83646034 Common - Transposase and inactivated derivatives HCH_03288 52 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 83646856 Nonpathogen - hypothetical protein HCH_04157 1 None None None 83645960 Nonpathogen - hypothetical protein HCH_03209 1 None None None 83645119 Common - Signal transduction histidine kinase HCH_02306 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83648581 Common obgE GTPase ObgE HCH_05939 248 COG0536 Obg, Predicted GTPase General function prediction only 83647015 Common - hypothetical protein HCH_04318 6 None None None 83648305 Common - hypothetical protein HCH_05658 4 None None None 83643015 Common - Ni,Fe-hydrogenase maturation factor HCH_00104 20 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 83647226 Nonpathogen - hypothetical protein HCH_04536 1 None None None 83646138 Nonpathogen - hypothetical protein HCH_03398 4 COG5620 COG5620, Uncharacterized conserved protein Function unknown 83645513 Common - Adenylylsulfate kinase and related kinase HCH_02737 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 83644450 Nonpathogen - hypothetical protein HCH_01603 2 None None None 83644402 Common - predicted metal-dependent hydrolase HCH_01555 82 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 83646523 Nonpathogen - hypothetical protein HCH_03801 1 None None None 83646343 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_03613 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643709 Common - hypothetical protein HCH_00826 3 None None None 83646046 Common - Archaeal fructose-1,6-bisphosphatase and related enzyme of inositol monophosphatase family HCH_03301 197 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 83646954 Common - hypothetical protein HCH_04257 11 COG1359 COG1359, Uncharacterized conserved protein Function unknown 83648368 Common - hypothetical protein HCH_05725 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 83646934 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_04237 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83643440 Common - FOG: CheY-like receiver HCH_00545 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644606 Common rpsP ribosomal protein S16 HCH_01772 207 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 83649560 Nonpathogen - hypothetical protein HCH_06954 1 None None None 83649458 Nonpathogen - hypothetical protein HCH_06848 1 None None None 83649621 Nonpathogen - hypothetical protein HCH_07016 3 None None None 83649451 Common - Zn-dependent protease HCH_06840 29 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 83645891 Common - hypothetical protein HCH_03137 21 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 83648829 Common rpsK 30S ribosomal protein S11 HCH_06195 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 83646987 Nonpathogen - hypothetical protein HCH_04290 2 None None None 83646485 Nonpathogen - hypothetical protein HCH_03763 1 None None None 83649583 Common - Transcriptional regulator HCH_06978 140 COG2188 PhnF, Transcriptional regulators Transcription 83646358 Common - hypothetical protein HCH_03628 61 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83643702 Common - hypothetical protein HCH_00819 8 COG4278 COG4278, Uncharacterized conserved protein Function unknown 83644367 Common - Lactate dehydrogenase and related dehydrogenase HCH_01519 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 83645096 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_02281 79 COG2962 RarD, Predicted permeases General function prediction only 83644782 Common - hypothetical protein HCH_01959 16 None None None 83647279 Common - hypothetical protein HCH_04588 20 None None None 83647800 Common - hypothetical protein HCH_05130 6 None None None 83647700 Common hsdR Type I site-specific restriction-modification system, R (restriction) subunit and related helicase HCH_05026 100 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 83648196 Nonpathogen - probable alpha-L-arabinofuranosidase B protein HCH_05546 4 None None None 83647052 Common - N-ethylammeline chlorohydrolase HCH_04356 179 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83645430 Common - predicted esterase of the alpha-beta hydrolase superfamily HCH_02651 5 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83644182 Nonpathogen - hypothetical protein HCH_01323 2 None None None 83645898 Nonpathogen - hypothetical protein HCH_03145 1 None None None 83649124 Nonpathogen - hypothetical protein HCH_06493 5 None None None 83646264 Common - hypothetical protein HCH_03530 67 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 83647305 Common groES Co-chaperonin GroES (HSP10) HCH_04614 211 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 83649136 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_06505 5 None None None 83648254 Nonpathogen - hypothetical protein HCH_05606 1 None None None 83649013 Common - predicted ATPase HCH_06378 22 COG0433 COG0433, Predicted ATPase General function prediction only 83649239 Common - hypothetical protein HCH_06615 23 COG0819 TenA, Putative transcription activator Transcription 83649665 Common - hypothetical protein HCH_07063 6 None None None 83646890 Common - Glycerol-3-phosphate dehydrogenase HCH_04193 139 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83644360 Nonpathogen - hypothetical protein HCH_01512 1 None None None 83646400 Common - protein containing EF-hand domain HCH_03670 8 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 83645629 Common - hypothetical protein HCH_02862 5 None None None 83648640 Common - hypothetical protein HCH_06000 22 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 83645966 Common - Transcriptional regulator HCH_03215 62 COG1846 MarR, Transcriptional regulators Transcription 83647471 Common - hypothetical protein HCH_04787 15 None None None 83648097 Common pspF psp operon transcription activator PspF (sigma 54-dependent) HCH_05441 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83648164 Common - Phosphopantetheinyl transferase component of siderophore synthetase HCH_05512 37 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 83646629 Nonpathogen - hypothetical protein HCH_03918 1 None None None 83643805 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_00925 210 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83647704 Common - predicted transcriptional regulator HCH_05031 9 COG3655 COG3655, Predicted transcriptional regulator Transcription 83644343 Common - hypothetical protein HCH_01495 2 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 83647740 Nonpathogen - hypothetical protein HCH_05067 1 None None None 83647916 Common tsf translation elongation factor Ts HCH_05252 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 83646336 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03606 16 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643574 Common - predicted phosphoribosyltransferase HCH_00684 72 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 83644789 Nonpathogen - hypothetical protein HCH_01965 1 None None None 83647341 Common - Lactoylglutathione lyase HCH_04652 26 None None None 83644351 Common add adenosine deaminase HCH_01503 101 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 83642954 Common - Carbonic anhydrases/acetyltransferase, isoleucine patch superfamily HCH_00042 188 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 83648647 Common prmA ribosomal protein L11 methyltransferase HCH_06007 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 83646491 Common - hypothetical protein HCH_03769 4 None None None 83647441 Common fadA 3-ketoacyl-CoA thiolase HCH_04754 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83647909 Common - Outer membrane protein/protective antigen OMA87 HCH_05243 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 83643798 Common atpF1 F0F1-type ATP synthase, subunit b HCH_00918 67 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 83645072 Nonpathogen - hypothetical protein HCH_02255 1 None None None 83643483 Common - hypothetical protein HCH_00590 24 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83647272 Common thrS2 threonyl-tRNA synthetase HCH_04580 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83649517 Common - ABC-type sugar transport system, permease components HCH_06909 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83647951 Nonpathogen - hypothetical protein HCH_05287 1 None None None 83643468 Common rpoH RNA polymerase factor sigma-32 HCH_00575 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 83648822 Common - D-alanine-D-alanine ligase and related ATP-grasp enzyme HCH_06188 229 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 83645664 Nonpathogen - hypothetical protein HCH_02900 1 None None None 83644587 Nonpathogen - hypothetical protein HCH_01752 1 None None None 83648363 Common - DNA G:T-mismatch repair endonuclease HCH_10021 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 83645486 Common prpB 2-methylisocitrate lyase HCH_02710 136 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 83647417 Common ligA DNA ligase, NAD-dependent HCH_04729 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 83644635 Common - Signal transduction histidine kinase HCH_01804 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644672 Common - Ribulose-5-phosphate 4-epimerase and related epimerase and aldolases HCH_01844 116 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 83645578 Nonpathogen - hypothetical protein HCH_02810 1 None None None 83646921 Common - Signal transduction histidine kinase HCH_04224 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 83646774 Common flgE1 Flagellar hook protein FlgE HCH_04071 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 83647731 Common - protein containing KWG Leptospira repeats HCH_05058 18 None None None 83645125 Common - uncharacterized ABC-type transport system, permease component HCH_02312 109 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 83645176 Nonpathogen - hypothetical protein HCH_02368 1 None None None 83645212 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase HCH_02412 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 83648269 Common - Transcriptional regulator HCH_05621 63 COG1309 AcrR, Transcriptional regulator Transcription 83648721 Common - ABC-type sugar transport system, periplasmic component HCH_06083 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83643654 Common - hypothetical protein HCH_00767 4 None None None 83643209 Nonpathogen - hypothetical protein HCH_00307 1 None None None 83645907 Nonpathogen - hypothetical protein HCH_03153 2 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83649399 Common - probable phage protein HCH_06785 12 None None None 83644330 Common - HD-GYP domain HCH_01482 113 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 83645129 Nonpathogen - hypothetical protein HCH_02316 11 None None None 83643854 Common - hypothetical protein HCH_00977 5 None None None 83649185 Common - predicted lipase HCH_06557 14 None None None 83643930 Common rfaE bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase HCH_01059 156 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 83643350 Common - Anti-anti-sigma regulatory factor HCH_00450 15 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 83648139 Nonpathogen - hypothetical protein HCH_05486 1 None None None 83643400 Common - hypothetical protein HCH_00503 26 COG3673 COG3673, Uncharacterized conserved protein Function unknown 83647327 Nonpathogen - hypothetical protein HCH_04638 1 None None None 83644489 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_01645 183 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83648119 Nonpathogen - hypothetical protein HCH_05466 1 None None None 83645384 Common - hypothetical protein HCH_02602 27 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 83645673 Nonpathogen - hypothetical protein HCH_02909 1 None None None 83649230 Common - TRAP-type C4-dicarboxylate transport system, small permease component HCH_06606 42 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 83649297 Common - hypothetical protein HCH_06677 103 COG1262 COG1262, Uncharacterized conserved protein Function unknown 83644879 Common - Short-chain dehydrogenase of various substrate specificities HCH_02058 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83644284 Common - hypothetical protein HCH_01433 8 None None None 83646618 Common - RTX toxins and related Ca2+-binding protein HCH_03906 110 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 83647543 Common - hypothetical protein HCH_04861 40 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 83644149 Nonpathogen - hypothetical protein HCH_01291 1 COG5406 COG5406, Nucleosome binding factor SPN, SPT16 subunit Transcription / DNA replication, recombination, and repair / Chromatin structure and dynamics 83643323 Nonpathogen - hypothetical protein HCH_00423 1 None None None 83645422 Common - Lysophospholipase HCH_02643 88 COG2267 PldB, Lysophospholipase Lipid metabolism 83648892 Common sfsA sugar fermentation stimulation protein HCH_06254 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 83648459 Common - Nitrate/nitrite transporter HCH_05818 127 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 83648436 Common - predicted ATPase (AAA+ superfamily) HCH_05795 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 83645409 Nonpathogen - hypothetical protein HCH_02629 3 None None None 83644508 Common - predicted unusual protein kinase HCH_01665 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83647784 Common yscT Type III secretory pathway, component EscT HCH_05113 115 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 83647133 Common - protein containing QXW lectin repeats HCH_04439 29 None None None 83646048 Common - protein containing QXW lectin repeats HCH_03303 14 None None None 83643939 Nonpathogen - hypothetical protein HCH_01068 1 None None None 83649177 Nonpathogen - hypothetical protein HCH_06548 1 None None None 83643184 Common - ATPase components of ABC transporters with duplicated ATPase domains HCH_00281 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83643859 Common - Transglutaminase-like enzyme, putative cysteine protease HCH_00982 93 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83647851 Common fliK Flagellar hook-length control protein HCH_05183 41 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 83648774 Common - S-adenosylmethionine decarboxylase HCH_06136 31 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 83644690 Common - predicted ATPase of the PP-loop superfamily implicated in cell cycle control HCH_01863 212 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 83648226 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_05578 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83648123 Common - hypothetical protein HCH_05470 2 None None None 83647770 Common - hypothetical protein HCH_05099 2 None None None 83643268 Nonpathogen - hypothetical protein HCH_00366 1 None None None 83646599 Common - hypothetical protein HCH_03882 39 COG3832 COG3832, Uncharacterized conserved protein Function unknown 83645338 Common - uncharacterized protein involved in the oxidation of intracellular sulfur HCH_02547 39 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 83647385 Common - hypothetical protein HCH_04697 4 None None None 83645885 Common - sigma 54-dependent transcriptional activator HCH_03131 161 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83647217 Common ureJ urease accessorry protein UreJ HCH_04527 16 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 83648188 Nonpathogen - hypothetical protein HCH_05537 1 None None None 83645100 Common mcrB GTPase subunit of restriction endonuclease HCH_02286 41 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 83644534 Common - sigma54-dependent transcription regulator RtcR HCH_01696 163 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 83647147 Common - FOG: WD40-like repeat HCH_04453 122 COG1520 COG1520, FOG: WD40-like repeat Function unknown 83645404 Common - hypothetical protein HCH_02624 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 83645491 Common - Periplasmic protein involved in polysaccharide export HCH_02715 110 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83647401 Common - Transcriptional regulator HCH_04713 187 COG0583 LysR, Transcriptional regulator Transcription 83648711 Nonpathogen - hypothetical protein HCH_06072 1 None None None 83646319 Common - Signal transduction histidine kinase HCH_03588 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 83647398 Nonpathogen - hypothetical protein HCH_04710 3 None None None 83646289 Nonpathogen - hypothetical protein HCH_03557 1 None None None 83647726 Common - ATP-dependent helicase HepA HCH_05053 138 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 83645734 Nonpathogen - hypothetical protein HCH_02975 1 None None None 83643228 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_00326 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83643587 Nonpathogen - hypothetical protein HCH_00698 1 None None None 83643430 Common - ABC-type Mn2+/Zn2+ transport system, permease components HCH_00535 198 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83645232 Common trpF Phosphoribosylanthranilate isomerase HCH_02435 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 83643773 Common - uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain HCH_00891 24 COG4245 TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain General function prediction only 83645310 Nonpathogen - hypothetical protein HCH_02518 1 None None None 83647375 Nonpathogen - hypothetical protein HCH_04687 13 None None None 83645429 Common - Surface lipoprotein HCH_02650 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 83643439 Common - Chemotaxis signal transduction protein HCH_00544 82 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83647113 Common - Transcriptional regulator HCH_04419 51 COG1522 Lrp, Transcriptional regulators Transcription 83642966 Common cyoE protoheme IX farnesyltransferase HCH_00054 172 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 83649195 Common - Glutamate-1-semialdehyde aminotransferase HCH_06567 236 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 83643172 Common - Glycosidase HCH_00269 131 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83647796 Nonpathogen - hypothetical protein HCH_05126 1 None None None 83647997 Nonpathogen - hypothetical protein HCH_05335 1 None None None 83644162 Nonpathogen - hypothetical protein HCH_01305 1 None None None 83648651 Common purH bifunctional purine biosynthesis protein PurH HCH_06011 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 83649578 Common - ABC-type sugar transport system, periplasmic component HCH_06973 40 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83648667 Common - hypothetical protein HCH_06027 4 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83646408 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_03678 91 None None None 83644385 Common pgk phosphoglycerate kinase HCH_01537 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 83646643 Common gspI general secretion pathway protein I HCH_03932 35 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 83646261 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family HCH_03526 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 83645770 Nonpathogen - hypothetical protein HCH_03012 1 None None None 83644070 Common - Transcriptional regulator HCH_01207 15 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 83645208 Common rfbA glucose-1-phosphate thymidylyltransferase HCH_02408 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 83648660 Common dapA3 dihydrodipicolinate synthase HCH_06020 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 83649616 Nonpathogen - hypothetical protein HCH_07011 7 None None None 83643550 Common - Hydrolase of the alpha/beta superfamily HCH_00659 64 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 83644801 Common mdh malate dehydrogenase HCH_01978 58 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 83646811 Common - hypothetical protein HCH_04111 3 None None None 83645357 Nonpathogen - hypothetical protein HCH_02567 1 None None None 83644320 Common - ABC-type spermidine/putrescine transport system, ATPase components HCH_01472 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83646249 Common - Membrane-fusion protein HCH_03513 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83646428 Common - Signal transduction histidine kinase HCH_03701 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646754 Nonpathogen - hypothetical protein HCH_04049 1 None None None 83645003 Common fadB 3-hydroxyacyl-CoA dehydrogenase HCH_02185 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 83648291 Common - Rhs family protein HCH_05643 126 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83644560 Common - translation-associated GTPase HCH_01722 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 83647891 Common - predicted ATP-dependent protease HCH_05226 104 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 83644097 Common tpiA triosephosphate isomerase HCH_01235 218 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 83648735 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06097 16 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649085 Common - Aldo/keto reductases, related to diketogulonate reductase HCH_06451 133 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 83648918 Common - hypothetical protein HCH_10029 7 None None None 83645366 Nonpathogen - hypothetical protein HCH_02576 3 None None None 83647254 Common - hypothetical protein HCH_04562 3 None None None 83649058 Common - Transcriptional accessory protein HCH_06423 217 COG2183 Tex, Transcriptional accessory protein Transcription 83645327 Common - Kef-type K+ transport system, predicted NAD-binding component HCH_02536 174 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 83648294 Common - hypothetical protein HCH_05645 3 None None None 83647063 Common - ABC-type transport system involved in cytochrome c biogenesis, permease component HCH_04367 123 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 83647900 Common - Ferredoxin HCH_05235 149 COG1146 COG1146, Ferredoxin Energy production and conversion 83643179 Common - hypothetical protein HCH_00276 39 None None None 83648034 Common - hypothetical protein HCH_05374 48 COG3268 COG3268, Uncharacterized conserved protein Function unknown 83643737 Common - ABC-type proline/glycine betaine transport system, ATPase component HCH_00854 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 83643088 Common - hypothetical protein HCH_00180 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 83643409 Common - Methyl-accepting chemotaxis protein HCH_00513 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83649631 Nonpathogen - hypothetical protein HCH_07027 1 None None None 83644580 Common minC septum formation inhibitor HCH_01744 89 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 83645255 Common - Methyl-accepting chemotaxis protein HCH_02458 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83645508 Common - Glycosyltransferase HCH_02733 87 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83643411 Nonpathogen - hypothetical protein HCH_00515 1 None None None 83645649 Nonpathogen - hypothetical protein HCH_02884 1 None None None 83644925 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_02106 181 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83648529 Common ftsL cell division protein FtsL HCH_05890 20 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 83643190 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase HCH_00287 89 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 83645023 Common - acetyltransferase (GNAT) family protein HCH_02205 3 COG3393 COG3393, Predicted acetyltransferase General function prediction only 83643546 Common - hypothetical protein HCH_00655 21 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 83648243 Common - predicted RNA polymerase sigma factor containing a TPR repeat domain HCH_05594 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 83648786 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_06149 222 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 83646580 Common - Transcriptional regulator HCH_03863 182 COG0583 LysR, Transcriptional regulator Transcription 83647354 Common - ABC-type transport system involved in multi-copper enzyme maturation, permease component HCH_04665 50 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 83645985 Common - hypothetical protein HCH_03235 21 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 83645671 Common - hypothetical protein HCH_02907 3 None None None 83649306 Nonpathogen - hypothetical protein HCH_06686 1 None None None 83642930 Common - hypothetical protein HCH_00017 3 None None None 83644480 Common - predicted transcriptional regulator HCH_01634 119 COG1396 HipB, Predicted transcriptional regulators Transcription 83648493 Common - predicted signal transduction protein HCH_05853 56 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83643884 Common - Ferredoxin HCH_01009 118 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 83643272 Nonpathogen - hypothetical protein HCH_00371 1 None None None 83644244 Common - Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain HCH_01391 220 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 83649625 Nonpathogen - hypothetical protein HCH_07020 2 None None None 83643523 Common - hypothetical protein HCH_00632 9 None None None 83645601 Nonpathogen - hypothetical protein HCH_02833 1 None None None 83647083 Common - Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 HCH_04388 104 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 83645435 Common - predicted Permease HCH_02656 72 COG0730 COG0730, Predicted permeases General function prediction only 83644334 Common - protein containing FG-GAP repeats HCH_01486 29 None None None 83643477 Nonpathogen - hypothetical protein HCH_00584 1 None None None 83643626 Common - O-Methyltransferase involved in polyketide biosynthesis HCH_00738 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83644774 Common astB succinylarginine dihydrolase HCH_01951 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 83646684 Nonpathogen - hypothetical protein HCH_03975 1 None None None 83645054 Common - SAM-dependent methyltransferase HCH_02238 52 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 83646419 Nonpathogen - hypothetical protein HCH_03690 1 None None None 83643715 Nonpathogen - hypothetical protein HCH_00832 2 None None None 83645925 Nonpathogen - hypothetical protein HCH_03172 1 None None None 83646716 Common narJ nitrate reductase molybdenum cofactor assembly chaperone HCH_04009 53 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 83646919 Common - Permease of the major facilitator superfamily HCH_04222 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83643710 Common - AraC-type DNA-binding domain-containing protein HCH_00827 69 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83647209 Common - ABC-type branched-chain amino acid transport system, periplasmic component HCH_04519 87 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83648181 Nonpathogen - hypothetical protein HCH_05529 1 None None None 83646746 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_04041 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83647656 Nonpathogen - hypothetical protein HCH_04976 1 None None None 83647586 Common - uncharacterized lipoprotein HCH_04905 23 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 83644973 Common glnS glutaminyl-tRNA synthetase HCH_02153 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83647410 Common - putative flagella synthesis protein FlgN HCH_04722 9 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 83649370 Nonpathogen - hypothetical protein HCH_06755 1 None None None 83645158 Common moxR MoxR-like ATPase HCH_02345 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 83647754 Common - ABC-type uncharacterized transport system involved in gliding motility, auxiliary component HCH_05083 17 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 83644961 Common rpmF 50S ribosomal protein L32 HCH_10002 65 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 83644397 Common - hypothetical protein HCH_01550 15 None None None 83645603 Nonpathogen - hypothetical protein HCH_02834 1 None None None 83647020 Nonpathogen - hypothetical protein HCH_04324 1 None None None 83643843 Common cobS Cobalamin-5-phosphate synthase HCH_00965 104 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 83644909 Nonpathogen - hypothetical protein HCH_02089 1 None None None 83643949 Common hisI1 Phosphoribosyl-AMP cyclohydrolase HCH_01079 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 83648032 Common - predicted dehydrogenase HCH_05373 121 COG0579 COG0579, Predicted dehydrogenase General function prediction only 83649296 Common - hypothetical protein HCH_06676 6 None None None 83649484 Nonpathogen - protein of unknown function (DUF1555) HCH_06876 1 None None None 83646247 Common - Transcriptional regulator HCH_03511 174 COG0583 LysR, Transcriptional regulator Transcription 83645818 Nonpathogen - hypothetical protein HCH_03062 1 None None None 83648929 Common - Metal-dependent amidase/aminoacylase/carboxypeptidase HCH_06291 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 83645175 Nonpathogen - hypothetical protein HCH_02367 1 None None None 83648701 Common - phytanoyl-CoA deoxygenase (PhyH) family protein HCH_06062 6 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83647944 Common - Type II secretory pathway, prepilin signal peptidase PulO and related peptidase HCH_05280 125 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83644274 Common - Truncated hemoglobin HCH_01422 25 COG2346 COG2346, Truncated hemoglobins General function prediction only 83643873 Common - Protein-disulfide isomerase HCH_00998 105 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 83645843 Common - ABC-type spermidine/putrescine transport system, ATPase components HCH_03087 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83644947 Common - SH3 domain protein HCH_02128 38 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 83646209 Nonpathogen - hypothetical protein HCH_03472 1 None None None 83644358 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_01510 29 COG0456 RimI, Acetyltransferases General function prediction only 83645523 Common atoC acetoacetate metabolism regulatory protein AtoC (sigma 54-dependent transcriptional regulator) HCH_02748 196 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83646577 Common - Glycine/serine hydroxymethyltransferase HCH_03860 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 83647675 Common phbB acetoacetyl-CoA reductase HCH_04996 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83643063 Nonpathogen - hypothetical protein HCH_00154 1 None None None 83646604 Nonpathogen - hypothetical protein HCH_03887 1 None None None 83648992 Common - hypothetical protein HCH_06357 76 COG1872 COG1872, Uncharacterized conserved protein Function unknown 83647182 Common queF 7-cyano-7-deazaguanine reductase HCH_04489 102 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 83642994 Common - Glycosyltransferase HCH_00083 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83648875 Common tyrS tyrosyl-tRNA synthetase HCH_06238 245 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83645993 Nonpathogen - hypothetical protein HCH_03243 1 None None None 83646004 Nonpathogen - hypothetical protein HCH_03255 1 None None None 83645866 Common - Hydrolase of the alpha/beta superfamily HCH_03110 45 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 83645784 Nonpathogen - hypothetical protein HCH_03027 1 None None None 83644002 Common - Methyl-accepting chemotaxis protein HCH_01134 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647528 Common - probable class 3 lipase HCH_04845 4 COG3675 COG3675, Predicted lipase Lipid metabolism 83643836 Common - hypothetical protein HCH_00958 5 None None None 83644060 Common - hypothetical protein HCH_01194 12 None None None 83647728 Common - hypothetical protein HCH_05055 6 None None None 83643294 Common - probable phage small terminate subunit HCH_00393 21 None None None 83647482 Common - hypothetical protein HCH_04798 11 None None None 83643780 Nonpathogen - hypothetical protein HCH_00899 1 None None None 83645617 Common - predicted metal-dependent protease of the PAD1/JAB1 superfamily HCH_02850 29 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 83643086 Nonpathogen - hypothetical protein HCH_00178 1 None None None 83643597 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00709 17 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648376 Nonpathogen - hypothetical protein HCH_05733 1 None None None 83647091 Nonpathogen - hypothetical protein HCH_04396 1 None None None 83644966 Common pabC 4-amino-4-deoxychorismate lyase HCH_02146 170 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83649090 Common - protein containing FG-GAP repeats HCH_06456 36 None None None 83649349 Common - predicted transcriptional regulator HCH_06733 147 COG1733 COG1733, Predicted transcriptional regulators Transcription 83645957 Nonpathogen - hypothetical protein HCH_03206 1 None None None 83644536 Common - predicted membrane protein HCH_01698 34 COG3431 COG3431, Predicted membrane protein Function unknown 83644659 Common - ABC-type oligopeptide transport system, ATPase component HCH_01830 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83648286 Common - predicted restriction endonuclease HCH_05638 35 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 83646777 Nonpathogen - hypothetical protein HCH_04074 1 None None None 83644620 Common - predicted aminomethyltransferase related to GcvT HCH_01786 107 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 83644564 Common ispE 4-diphosphocytidyl-2C-methyl-D-erythritol kinase HCH_01727 188 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 83646991 Common - Hemolysin-coregulated protein (uncharacterized) HCH_04294 25 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 83647848 Common fliN flagellar motor switch protein HCH_05180 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83646092 Common - Transcriptional regulator HCH_03348 121 COG0583 LysR, Transcriptional regulator Transcription 83647045 Common - predicted flavoprotein involved in K+ transport HCH_04349 73 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 83643915 Common - hypothetical protein HCH_01043 23 None None None 83648947 Common - Transcriptional regulator HCH_06310 189 COG0583 LysR, Transcriptional regulator Transcription 83647067 Common - uncharacterized flagellar protein FhlB cytoplasmic domain HCH_04371 79 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 83646501 Nonpathogen - hypothetical protein HCH_03779 1 None None None 83648068 Common - Acyl-CoA thioesterase HCH_05409 19 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 83648448 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05807 120 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646391 Nonpathogen - hypothetical protein HCH_03661 2 None None None 83648677 Common - predicted membrane protein HCH_06037 39 COG3752 COG3752, Predicted membrane protein Function unknown 83646072 Nonpathogen - hypothetical protein HCH_03327 1 None None None 83645333 Common metH B12-dependent methionine synthase HCH_02542 175 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 83646310 Nonpathogen - hypothetical protein HCH_03578 2 None None None 83644366 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_01518 171 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83645465 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C HCH_02687 48 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 83644940 Common - predicted Zn-dependent peptidase, insulinase-like HCH_02121 99 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 83647840 Common - flagellar synthesis regulator FleN HCH_05172 124 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83647318 Common - hypothetical protein HCH_04629 12 None None None 83645308 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_02516 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83645932 Nonpathogen - hypothetical protein HCH_03179 1 None None None 83647138 Common - predicted signal transduction protein containing EAL and modified HD-GYP domains HCH_04444 56 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 83645048 Common - ABC-type polysaccharide/polyol phosphate transport system, ATPase component HCH_02231 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 83647432 Common kgd alpha-ketoglutarate decarboxylase HCH_04745 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 83646478 Common - predicted glutamine amidotransferase HCH_03755 118 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 83647519 Common - Sialic acid synthase HCH_04835 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 83644576 Common - FOG: CBS domain HCH_01740 48 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 83646079 Common - Thiol:disulfide interchange protein HCH_03335 112 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83648557 Common ilvB1 acetolactate synthase 3 catalytic subunit HCH_05916 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83647042 Nonpathogen - hypothetical protein HCH_04346 1 None None None 83647378 Common - predicted glycosyltransferase HCH_04690 87 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 83647493 Common - Methyl-accepting chemotaxis protein HCH_04809 137 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643277 Common - probable phage protein HCH_00376 5 None None None 83649033 Common - hypothetical protein HCH_06396 51 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 83647950 Common - Signal transduction histidine kinase HCH_05286 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646651 Common - predicted transcriptional regulator HCH_03942 110 COG0789 SoxR, Predicted transcriptional regulators Transcription 83648201 Nonpathogen - hypothetical protein HCH_05551 1 None None None 83646665 Common - Retron-type reverse transcriptase HCH_03956 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83648309 Nonpathogen - hypothetical protein HCH_05662 1 None None None 83647415 Common - protein containing CBS domains HCH_04727 17 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 83646307 Nonpathogen - hypothetical protein HCH_03574 7 None None None 83647125 Common - hypothetical protein HCH_04431 9 None None None 83647576 Common - Ribonucleotide reductase, alpha subunit HCH_04895 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 83646535 Common - predicted dienelactone hydrolase HCH_03814 20 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 83643521 Common - hypothetical protein HCH_00629 29 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 83643768 Common - hypothetical protein HCH_00886 5 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 83642998 Common - Endoglucanase HCH_00087 33 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 83644130 Common aceE pyruvate dehydrogenase subunit E1 HCH_01272 136 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 83648867 Common - hypothetical protein HCH_10028 2 None None None 83644126 Common - hypothetical protein HCH_01268 76 COG1556 COG1556, Uncharacterized conserved protein Function unknown 83649691 Nonpathogen - hypothetical protein HCH_07088 1 None None None 83645596 Nonpathogen - hypothetical protein HCH_02828 1 None None None 83647765 Nonpathogen - hypothetical protein HCH_05094 1 None None None 83646180 Common - Polyketide synthase modules and related protein HCH_03442 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83643562 Common - FOG: CheY-like receiver HCH_00672 209 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83646077 Common - Acyl carrier protein phosphodiesterase HCH_03333 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 83647284 Common - hypothetical protein HCH_04593 18 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 83643095 Common - translation initiation factor Sui1 HCH_00188 64 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 83645741 Nonpathogen - hypothetical protein HCH_02982 1 None None None 83644179 Nonpathogen - hypothetical protein HCH_01321 2 None None None 83648479 Common - D-alanyl-D-alanine carboxypeptidase HCH_05839 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 83644473 Common - Response regulator HCH_01627 215 COG4566 TtrR, Response regulator Signal transduction mechanisms 83645041 Common rsmC 16S RNA G1207 methylase RsmC HCH_02224 114 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 83649259 Common - predicted aminoglycoside phosphotransferase HCH_06636 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 83644470 Nonpathogen - hypothetical protein HCH_01624 1 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83645361 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02571 43 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649634 Common - Membrane carboxypeptidase/penicillin-binding protein PbpC HCH_07030 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 83649664 Common - Transposase and inactivated derivatives HCH_07062 13 None None None 83645144 Common purB adenylosuccinate lyase HCH_02331 229 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 83644814 Common - Micrococcal nuclease-like protein HCH_01990 15 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 83646693 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_03985 34 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 83646382 Nonpathogen - hypothetical protein HCH_03652 1 None None None 83647921 Nonpathogen - hypothetical protein HCH_05256 1 None None None 83645804 Common - hypothetical protein HCH_03048 4 None None None 83645656 Nonpathogen - hypothetical protein HCH_02892 1 None None None 83645809 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_03053 171 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83648596 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase HCH_05955 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 83643402 Common - Cytochrome c peroxidase HCH_00505 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 161897900 Common hemA glutamyl-tRNA reductase HCH_01731 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 83645265 Common - ABC-type sugar transport system, ATPase component HCH_02469 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 83643500 Nonpathogen - hypothetical protein HCH_00607 1 None None None 83647219 Nonpathogen - hypothetical protein HCH_04528 1 None None None 83647831 Common - protein containing CheW-like domain HCH_05162 14 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83648046 Common - N-acetylmuramoyl-L-alanine amidase HCH_05387 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 83644068 Nonpathogen - hypothetical protein HCH_01205 2 None None None 83643743 Common - Signal transduction histidine kinase HCH_00861 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83648203 Nonpathogen - predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon HCH_05553 14 COG3357 COG3357, Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon Transcription 83649531 Common - Short-chain dehydrogenase of various substrate specificities HCH_06924 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83643606 Nonpathogen - hypothetical protein HCH_00718 3 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 83643485 Common - hypothetical protein HCH_00592 8 None None None 83645167 Common - Transposase and inactivated derivatives HCH_02354 5 None None None 83649675 Common atpA2 ATP synthase F1, alpha subunit HCH_07073 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 83646274 Common - TRAP-type mannitol/chloroaromatic compound transport system, large permease component HCH_03542 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 83645802 Common - hypothetical protein HCH_03046 4 None None None 83647295 Common purK Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) HCH_04604 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 83642987 Common hypB hydrogenase accessory protein HypB HCH_00076 153 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 83645922 Nonpathogen - protein of unknown function (DUF1555) HCH_03169 1 None None None 83647911 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase HCH_05246 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 83644310 Nonpathogen - hypothetical protein HCH_01461 1 None None None 83649491 Nonpathogen - hypothetical protein HCH_06883 1 None None None 83646460 Nonpathogen - hypothetical protein HCH_03736 1 None None None 83647463 Nonpathogen - hypothetical protein HCH_04779 1 None None None 83647819 Common - Signal transduction histidine kinase HCH_05149 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83646389 Nonpathogen - hypothetical protein HCH_03659 1 None None None 83644857 Common azlC predicted branched-chain amino acid permease (azaleucine resistance) HCH_02033 63 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 83643251 Common eda 2-keto-3-deoxy-6-phosphogluconate aldolase HCH_00349 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 83648514 Common - Membrane protein related to metalloendopeptidase HCH_05874 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83644661 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_01832 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83644802 Common - hypothetical protein HCH_01979 6 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648506 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase HCH_05866 224 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 83645249 Common modC molybdate ABC transporter, ATP-binding protein HCH_02452 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 83647173 Common flgE2 Flagellar hook protein FlgE HCH_04479 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 83647653 Nonpathogen - hypothetical protein HCH_04973 1 None None None 83649118 Nonpathogen - hypothetical protein HCH_06487 8 None None None 83647780 Common - hypothetical protein HCH_05109 177 None None None 83643046 Common thiC thiamine biosynthesis protein ThiC HCH_00137 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 83645691 Common - AraC-type DNA-binding domain-containing protein HCH_02929 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645028 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02210 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644234 Nonpathogen - hypothetical protein HCH_01381 1 None None None 83644652 Common putP sodium/proline symporter HCH_01823 136 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 83643556 Nonpathogen - hypothetical protein HCH_00666 6 None None None 83647548 Nonpathogen - hypothetical protein HCH_04867 1 None None None 83644553 Common alr alanine racemase HCH_01715 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 83646567 Nonpathogen - Chemotaxis signal transduction protein HCH_03849 9 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83643004 Common - protein containing autotransporter beta-domain HCH_00093 59 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 83649588 Nonpathogen - hypothetical protein HCH_06983 1 None None None 83644139 Common - AraC-type DNA-binding domain-containing protein HCH_01281 150 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83647075 Nonpathogen - hypothetical protein HCH_04380 1 None None None 83645637 Nonpathogen - hypothetical protein HCH_02871 1 None None None 83644543 Common - dihydroorotase HCH_01704 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 83643037 Common - putative threonine efflux protein HCH_00127 75 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83648708 Common - Methyl-accepting chemotaxis protein HCH_06069 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643787 Nonpathogen - hypothetical protein HCH_00906 1 None None None 83644047 Common - Transposase and inactivated derivatives HCH_01181 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643132 Nonpathogen - hypothetical protein HCH_00227 1 None None None 83646868 Common hutU urocanate hydratase HCH_04171 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 83646210 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03473 16 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648959 Common - hypothetical protein HCH_06323 6 None None None 83648406 Common - Transcriptional regulator HCH_05765 121 COG0583 LysR, Transcriptional regulator Transcription 83647745 Common - Na+/proline symporter HCH_05072 228 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 83643971 Common - ABC-type uncharacterized transport system, ATPase components HCH_01101 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 83644753 Common holC DNA polymerase III, chi subunit HCH_01930 20 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 83647716 Common - predicted metal-dependent hydrolase HCH_05043 146 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 83644701 Common pcm protein-L-isoaspartate O-methyltransferase HCH_01874 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 83645539 Common - Selenocysteine lyase HCH_02765 232 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 83649201 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase components HCH_06574 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83649340 Common - uncharacterized iron-regulated protein HCH_06724 12 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 83647103 Common norD Nitric oxide reductase activation protein HCH_04408 45 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 83643122 Common - Transcriptional regulator HCH_00217 174 COG0583 LysR, Transcriptional regulator Transcription 83647903 Common lpxB lipid-A-disaccharide synthase HCH_05238 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 83643680 Nonpathogen - hypothetical protein HCH_00795 1 None None None 83649105 Common cobH Precorrin isomerase HCH_06473 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 83645183 Common comEA DNA uptake protein and related DNA-binding protein HCH_02375 92 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 83649515 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase HCH_06907 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 83643299 Common - hypothetical protein HCH_00398 13 None None None 83644084 Common recN DNA repair protein RecN HCH_01222 209 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 83648051 Common - ribosome-associated GTPase HCH_05392 163 COG1162 COG1162, Predicted GTPases General function prediction only 83644541 Common - Fe2+/Zn2+ uptake regulation protein HCH_01703 105 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83647321 Common - predicted acyl-CoA transferase/carnitine dehydratase HCH_04632 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 83643511 Nonpathogen - hypothetical protein HCH_00619 1 None None None 83643234 Common - hypothetical protein HCH_00331 8 None None None 83649658 Nonpathogen - hypothetical protein HCH_07056 2 None None None 83646347 Nonpathogen - hypothetical protein HCH_03617 6 None None None 83643781 Nonpathogen - hypothetical protein HCH_00900 1 None None None 83645013 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_02196 132 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 83647251 Common - predicted transcriptional regulator containing the CopG/Arc/MetJ DNA-binding domain HCH_04560 25 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 83648563 Common - NAD synthase HCH_05923 227 COG0171 NadE, NAD synthase Coenzyme metabolism 83645063 Common - Transcriptional regulator HCH_02247 57 COG1309 AcrR, Transcriptional regulator Transcription 83648811 Common - Membrane protein involved in the export of O-antigen and teichoic acid HCH_06176 139 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83645698 Nonpathogen - hypothetical protein HCH_02936 1 None None None 83645999 Common - Flagellar biosynthesis/type III secretory pathway protein HCH_03249 11 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83644001 Nonpathogen - hypothetical protein HCH_01133 1 None None None 83646884 Nonpathogen - hypothetical protein HCH_04187 1 None None None 83644529 Nonpathogen - hypothetical protein HCH_01688 1 None None None 83648698 Nonpathogen - hypothetical protein HCH_06059 2 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 83646234 Nonpathogen - hypothetical protein HCH_03498 1 None None None 83642945 Common - predicted Rossmann fold nucleotide-binding protein involved in DNA uptake HCH_00032 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 83649313 Nonpathogen - hypothetical protein HCH_06694 1 None None None 83648153 Common - sigma54-dependent transcription regulator RtcR HCH_05501 163 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 83647159 Common - Archaeal fructose-1,6-bisphosphatase and related enzyme of inositol monophosphatase family HCH_04465 176 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 83646479 Nonpathogen - hypothetical protein HCH_03757 10 None None None 83647538 Nonpathogen - hypothetical protein HCH_04855 1 None None None 83648788 Common - Type II secretory pathway, component ExeA (predicted ATPase) HCH_06152 72 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 83644073 Nonpathogen - hypothetical protein HCH_01210 1 None None None 83645117 Common - Glutathione peroxidase HCH_02304 115 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 83646100 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_03356 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83648087 Common - predicted transcriptional regulator HCH_05431 61 COG0640 ArsR, Predicted transcriptional regulators Transcription 83643964 Common - hypothetical protein HCH_01094 42 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 83647153 Common - predicted Fe-S-cluster redox enzyme HCH_04459 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 83646257 Common - Polyferredoxin HCH_03522 77 COG0348 NapH, Polyferredoxin Energy production and conversion 83647533 Common - Methyl-accepting chemotaxis protein HCH_04850 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647007 Common grxA glutaredoxin 1 HCH_04310 37 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 83643977 Nonpathogen - hypothetical protein HCH_01109 1 None None None 83645941 Common - ATPase components of ABC transporters with duplicated ATPase domains HCH_03188 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83645827 Common - predicted phosphatase HCH_03071 77 COG0546 Gph, Predicted phosphatases General function prediction only 83646803 Common - Negative regulator of beta-lactamase expression HCH_04102 14 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 83642974 Common phrB1 Deoxyribodipyrimidine photolyase HCH_00062 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 83648637 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase HCH_05997 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 83649369 Nonpathogen - hypothetical protein HCH_06754 1 None None None 83644913 Common - Rhs family protein HCH_02093 74 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83648441 Nonpathogen - hypothetical protein HCH_05800 1 None None None 83648849 Common rplB 50S ribosomal protein L2 HCH_06214 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 83647880 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05214 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643533 Common mmsA1 methylmalonate-semialdehyde dehydrogenase HCH_00642 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83648147 Nonpathogen - hypothetical protein HCH_05494 2 None None None 83643470 Common gip Hydroxypyruvate isomerase HCH_00577 82 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 83643641 Common phoU phosphate transport system regulatory protein PhoU HCH_00754 193 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 83644722 Common metG Methionyl-tRNA synthetase HCH_01897 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83646844 Common - FOG: GGDEF domain HCH_04145 161 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643519 Nonpathogen - hypothetical protein HCH_00627 1 None None None 83647692 Common - Tfp pilus assembly protein, ATPase PilU HCH_05017 211 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 83644211 Common secB preprotein translocase subunit SecB HCH_01356 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 83643021 Common - Glutathione peroxidase HCH_00110 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 83648985 Common - hypothetical protein HCH_06349 10 None None None 83646379 Common - Molecular chaperone HCH_03649 216 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83645110 Nonpathogen - hypothetical protein HCH_02297 1 None None None 83644928 Common - Spermidine/putrescine-binding periplasmic protein HCH_02109 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83643983 Nonpathogen - hypothetical protein HCH_01115 1 None None None 83648733 Common - prephenate dehydratase HCH_06095 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 83644767 Common - Methyl-accepting chemotaxis protein HCH_01944 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647993 Common maf2 maf protein HCH_05331 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 83644016 Common - hypothetical protein HCH_01149 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 83646338 Common - Zn-finger domain associated with topoisomerase type I HCH_03608 16 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 83647264 Common - Integrase HCH_04571 17 None None None 83646084 Common - predicted Zn-dependent Hydrolase of the beta-lactamase fold HCH_03340 97 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 83643892 Common - Metal-dependent hydrolase HCH_01017 39 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 83643372 Common - Rhs family protein HCH_00473 75 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83649352 Common - hypothetical protein HCH_06737 15 COG4633 COG4633, Uncharacterized protein conserved in bacteria Function unknown 83646649 Common - predicted periplasmic protein HCH_03939 37 COG3672 COG3672, Predicted periplasmic protein Function unknown 83649465 Common - Cation transport ATPase HCH_06855 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 83643304 Nonpathogen - hypothetical protein HCH_00403 1 None None None 83647506 Common - Flagellin and related hook-associated protein HCH_04822 145 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83645938 Nonpathogen - hypothetical protein HCH_03185 2 None None None 83646195 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase components HCH_03458 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83647553 Common - predicted phosphatase HCH_04872 115 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 83648453 Common - predicted epimerase PhzC/PhzF-like protein HCH_05812 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 83646603 Nonpathogen - hypothetical protein HCH_03889 1 None None None 83644465 Common - Signal transduction histidine kinase regulating C4-dicarboxylate transport system HCH_01618 207 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83646345 Nonpathogen - hypothetical protein HCH_03615 1 None None None 83649479 Nonpathogen - hypothetical protein HCH_06871 3 None None None 83644997 Common - Signal transduction histidine kinase HCH_02179 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 83644625 Common mucA sigma factor algU negative regulatory protein MucA HCH_01791 9 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 83644794 Nonpathogen - hypothetical protein HCH_01971 1 None None None 83648598 Common ribD riboflavin biosynthesis protein RibD HCH_05957 228 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 83647331 Common - FOG: TPR repeat HCH_04642 21 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 83648740 Common apaG ApaG HCH_06102 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 83645755 Nonpathogen - hypothetical protein HCH_02996 1 None None None 83644447 Nonpathogen - hypothetical protein HCH_01600 1 None None None 83646435 Nonpathogen - hypothetical protein HCH_03708 1 None None None 83648796 Common - Serine acetyltransferase HCH_06160 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83646511 Common - Membrane-fusion protein HCH_03789 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83646585 Nonpathogen - hypothetical protein HCH_03868 1 None None None 83648961 Common - hypothetical protein HCH_06325 26 None None None 83647634 Common - Methyl-accepting chemotaxis protein HCH_04955 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83642980 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_00069 45 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83646040 Common - hypothetical protein HCH_03295 6 None None None 83647188 Nonpathogen - hypothetical protein HCH_04496 1 None None None 83646226 Common - Polyketide synthase modules and related protein HCH_03490 12 None None None 83644108 Common - hypothetical protein HCH_01247 15 None None None 83649072 Nonpathogen - hypothetical protein HCH_06437 2 None None None 83645149 Common icd isocitrate dehydrogenase, NADP-dependent HCH_02336 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 83645084 Common ccoS cytochrome oxidase maturation protein, cbb3-type HCH_02268 43 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 83643081 Common - predicted nucleotidyltransferase HCH_00172 21 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 83648764 Common - Anthranilate/para-aminobenzoate synthases component II HCH_06126 235 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 83648842 Common rplN 50S ribosomal protein L14 HCH_06207 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 83648950 Common - Guanosine polyphosphate pyrophosphohydrolase/synthetases HCH_06313 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 83645448 Common holB DNA polymerase III delta prime subunit HCH_02670 215 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 83643079 Common - D-amino acid dehydrogenase small subunit HCH_00170 145 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83646188 Common - Non-ribosomal peptide synthetase modules and related protein HCH_03451 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648538 Common - Cytochrome c1 HCH_05898 67 COG2857 CYT1, Cytochrome c1 Energy production and conversion 83649360 Common - Transcriptional regulator HCH_06745 193 COG0583 LysR, Transcriptional regulator Transcription 83643549 Common - ABC-type antimicrobial peptide transport system, permease component HCH_00658 45 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 83646125 Common - ABC-type transport system involved in multi-copper enzyme maturation, permease component HCH_03385 48 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 83648470 Common - ABC-type branched-chain amino acid transport system, periplasmic component HCH_05830 36 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83644268 Common sufB cysteine desulfurase activator complex subunit SufB HCH_01416 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 83644676 Common - Signal transduction histidine kinase HCH_01848 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83645188 Common - uncharacterized protein involved in exopolysaccharide biosynthesis HCH_02381 11 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 83646947 Common - hypothetical protein HCH_04250 29 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 83644988 Common - predicted xylanase/chitin deacetylase HCH_02169 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 83645560 Common - peptidase family S41 protein HCH_02791 89 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 83647509 Common - Imidazoleglycerol-phosphate synthase HCH_04825 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 83649249 Common - Long-chain acyl-CoA synthetases (AMP-forming) HCH_06625 200 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 83642924 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_00011 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83643636 Common - ABC-type phosphate transport system, periplasmic component HCH_00749 120 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 83645820 Nonpathogen - hypothetical protein HCH_03064 1 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83648500 Common - hypothetical protein HCH_05861 48 COG3332 COG3332, Uncharacterized conserved protein Function unknown 83647695 Common - SAM-dependent methyltransferase HCH_05020 49 None None None 83647311 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_04621 216 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83645948 Nonpathogen - hypothetical protein HCH_03197 1 None None None 83649335 Common - Asparaginase HCH_06718 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 83648150 Common - ATPase with chaperone activity, ATP-binding subunit HCH_05498 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83645873 Nonpathogen - hypothetical protein HCH_03118 1 None None None 83644748 Common - Methyl-accepting chemotaxis protein HCH_01925 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648465 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05825 8 None None None 83648781 Common - hypothetical protein HCH_06143 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 83645931 Nonpathogen - hypothetical protein HCH_03178 1 None None None 83648974 Common rph ribonuclease PH HCH_06338 188 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 83644979 Common clpX ATP-dependent protease ATP-binding subunit HCH_02160 236 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 83644453 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_01606 17 COG0456 RimI, Acetyltransferases General function prediction only 83645077 Nonpathogen - hypothetical protein HCH_02261 1 None None None 83647682 Common - protein containing BNR/Asp-box repeats HCH_05006 11 None None None 83646363 Common - FOG: CheY-like receiver HCH_03633 215 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83644433 Common - putative Zn-dependent protease, contains TPR repeats HCH_01586 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83648326 Nonpathogen - hypothetical protein HCH_05681 6 None None None 83646372 Common - major facilitator superfamily protein HCH_03642 32 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83646298 Nonpathogen - hypothetical protein HCH_03566 1 COG4907 COG4907, Predicted membrane protein Function unknown 83648646 Common accC1 acetyl-CoA carboxylase, biotin carboxylase HCH_06006 234 COG0439 AccC, Biotin carboxylase Lipid metabolism 83643615 Nonpathogen - hypothetical protein HCH_00727 7 None None None 83647584 Common - hypothetical protein HCH_04903 17 None None None 83647302 Common gspC general secretion pathway protein C HCH_04611 18 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 83649191 Common - Isochorismate synthase HCH_06563 222 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83644833 Common - putative translation initiation inhibitor, yjgF family HCH_02009 108 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 83646552 Common feoA2 Fe2+ transport system protein A HCH_03834 68 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 83646156 Common - probable glycosyltransferase HCH_03418 13 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 83646965 Common - hypothetical protein HCH_04268 14 None None None 83644204 Common - hypothetical protein HCH_01349 66 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 83646970 Common - TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component HCH_04273 93 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83647194 Common - ABC-type uncharacterized transport system, permease component HCH_04502 66 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 83644419 Common - predicted transcriptional regulator HCH_01572 54 COG2345 COG2345, Predicted transcriptional regulator Transcription 83645477 Common - Biopolymer transport protein HCH_02700 154 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 83648932 Common - short chain dehydrogenase HCH_06294 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83647825 Common - Cation transport ATPase HCH_05156 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 83648994 Common metX homoserine O-acetyltransferase HCH_06359 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 83648056 Common psd phosphatidylserine decarboxylase HCH_05397 98 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 83646739 Nonpathogen - hypothetical protein HCH_04034 3 None None None 83649271 Common - L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D HCH_06648 135 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 83649413 Common - AraC-type DNA-binding domain-containing protein HCH_06799 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646956 Common - putative translation initiation inhibitor, yjgF family HCH_04259 88 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 83645301 Common - ABC-type sugar transport system, periplasmic component HCH_02509 41 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83649119 Common - putative threonine efflux protein HCH_06488 54 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83646166 Common - Periplasmic protein involved in polysaccharide export HCH_03428 124 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83643816 Common - predicted phosphoesterases, related to the Icc protein HCH_00937 32 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 83647663 Common gyrA DNA gyrase, A subunit HCH_04983 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 83646280 Common - Thiol-disulfide isomerase and thioredoxins HCH_03548 24 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83646144 Common - predicted thioesterase HCH_03404 14 COG0824 FcbC, Predicted thioesterase General function prediction only 83647949 Common - hypothetical protein HCH_05284 5 None None None 83649127 Common - predicted membrane protein HCH_06496 98 COG1238 COG1238, Predicted membrane protein Function unknown 83647332 Nonpathogen - hypothetical protein HCH_04643 1 None None None 83648600 Common - Glycine/serine hydroxymethyltransferase HCH_05959 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 83643687 Common mnhD putative monovalent cation/H+ antiporter subunit D HCH_00802 205 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 83649437 Common - Na+-driven multidrug efflux pump HCH_06824 169 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83646469 Common - predicted acetyltransferase HCH_03745 44 COG3153 COG3153, Predicted acetyltransferase General function prediction only 83643479 Nonpathogen - hypothetical protein HCH_00586 2 None None None 83644193 Nonpathogen - hypothetical protein HCH_01336 1 None None None 83647160 Common secF preprotein translocase subunit SecF HCH_04466 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 83645192 Common - predicted carbamoyl transferase, NodU family HCH_02387 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 83649443 Common - ABC-type Fe3+-hydroxamate trasport system, periplasmic component HCH_06832 51 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 83646765 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04060 83 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646939 Common - Serine/threonine protein kinase HCH_04242 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83648520 Common - D-alanine-D-alanine ligase and related ATP-grasp enzyme HCH_05881 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 83647381 Common - Glycosyltransferase involved in cell wall biogenesis HCH_04693 193 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83647514 Common - hypothetical protein HCH_04830 4 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83647975 Common - ABC-type transport system involved in resistance to organic solvents, periplasmic component HCH_05312 111 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83644117 Common - Thioredoxin domain-containing protein HCH_01258 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 83646975 Common - hypothetical protein HCH_04278 9 None None None 83642949 Common aroE Shikimate 5-dehydrogenase HCH_00037 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 83647814 Common - Transcriptional regulator HCH_05144 160 COG1522 Lrp, Transcriptional regulators Transcription 83647000 Common - FOG: CheY-like receiver HCH_04303 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83643341 Common malF maltose transporter membrane protein HCH_00441 169 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83644688 Common dnaE DNA polymerase III subunit alpha HCH_01861 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 83649104 Common - hypothetical protein HCH_06472 79 COG2138 COG2138, Uncharacterized conserved protein Function unknown 83644023 Nonpathogen - hypothetical protein HCH_01156 1 None None None 83643937 Common - hypothetical protein HCH_01066 10 None None None 83645498 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02723 175 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648544 Common prfC peptide chain release factor 3 HCH_05904 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 83645592 Common - SAM-dependent methyltransferase HCH_02824 44 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83645222 Common - ATP-dependent protease HslVU (ClpYQ), ATPase subunit HCH_02424 9 None None None 83647590 Common - predicted permease HCH_04909 204 COG0628 PerM, Predicted permease General function prediction only 83649470 Common - Serine/threonine protein kinase HCH_06862 158 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83644379 Common metF 5,10-methylenetetrahydrofolate reductase HCH_01531 147 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 83644825 Common - Spermidine/putrescine-binding periplasmic protein HCH_02001 125 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83644198 Nonpathogen - hypothetical protein HCH_01341 6 None None None 83644614 Common thrC threonine synthase HCH_01780 132 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 83643056 Common - hypothetical protein HCH_00147 19 None None None 83644934 Common - 6-pyruvoyl-tetrahydropterin synthase HCH_02115 16 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 83643245 Common - hypothetical protein HCH_00343 3 None None None 83643509 Nonpathogen - hypothetical protein HCH_00617 1 None None None 83648179 Common - hypothetical protein HCH_05527 2 None None None 83644525 Nonpathogen - hypothetical protein HCH_01684 1 None None None 83648551 Common - hypothetical protein HCH_10006 6 None None None 83649336 Common - Methyl-accepting chemotaxis protein HCH_06719 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643739 Common - predicted integral membrane protein HCH_00856 24 COG5473 COG5473, Predicted integral membrane protein Function unknown 83649576 Nonpathogen - hypothetical protein HCH_06971 1 None None None 83644677 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_01849 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644766 Nonpathogen - hypothetical protein HCH_01943 1 None None None 83649008 Common - predicted transcriptional regulator HCH_10030 11 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 83646286 Nonpathogen - hypothetical protein HCH_03554 1 None None None 83648979 Nonpathogen - hypothetical protein HCH_06343 2 None None None 83645680 Common - hypothetical protein HCH_02916 3 None None None 83648177 Common - Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit HCH_05525 70 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 83646434 Common - Methyl-accepting chemotaxis protein HCH_03707 119 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83644319 Common - Spermidine/putrescine-binding periplasmic protein HCH_01471 132 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83645704 Common - ABC-type Zn2+ transport system, periplasmic component/surface adhesin HCH_02942 175 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83646009 Common - Type III secretory pathway, component EscU HCH_03260 129 COG4792 EscU, Type III secretory pathway, component EscU Intracellular trafficking and secretion 83647263 Common - Transposase and inactivated derivatives HCH_04570 51 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83646634 Common - ABC-type uncharacterized transport system, periplasmic component HCH_03923 10 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 83647588 Common - Glycine cleavage system regulatory protein HCH_04907 43 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 83648006 Nonpathogen - hypothetical protein HCH_05343 1 None None None 83646146 Common - putative NADPH-quinone reductase (modulator of drug activity B) HCH_03407 70 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 83644944 Common menG ribonuclease activity regulator protein RraA HCH_02125 104 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 83646081 Common - AraC-type DNA-binding domain-containing protein HCH_03338 138 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83644923 Nonpathogen - hypothetical protein HCH_02104 1 None None None 83648523 Common - Bacterial cell division membrane protein HCH_05884 205 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 83646715 Common narI respiratory nitrate reductase, gamma subunit HCH_04008 60 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 83646348 Common - Zn-dependent Hydrolase, including glyoxylases HCH_03618 91 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83643208 Nonpathogen - hypothetical protein HCH_00306 1 None None None 83647813 Common - Transcriptional regulator HCH_05143 96 COG1846 MarR, Transcriptional regulators Transcription 83644192 Nonpathogen - hypothetical protein HCH_01335 1 None None None 83645191 Common - hypothetical protein HCH_02386 5 None None None 83646747 Common uvrC excinuclease ABC subunit C HCH_04042 225 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 83647547 Nonpathogen - hypothetical protein HCH_04866 1 None None None 83647940 Common - Tfp pilus assembly protein, major pilin PilA HCH_05276 19 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 83646229 Common - hypothetical protein HCH_03493 4 None None None 83648462 Common - Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenases HCH_05822 68 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 83648675 Nonpathogen - 4'-phosphopantetheinyl transferase family protein HCH_06035 4 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 83642972 Nonpathogen - hypothetical protein HCH_00060 2 None None None 83644081 Common - hypothetical protein HCH_01218 65 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 83644243 Common - Signal transduction histidine kinase HCH_01390 178 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647078 Common - hypothetical protein HCH_04383 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 83644135 Nonpathogen - hypothetical protein HCH_01277 1 None None None 83647820 Common - Response regulator HCH_05150 187 COG4566 TtrR, Response regulator Signal transduction mechanisms 83643929 Common - Lauroyl/myristoyl acyltransferase HCH_01058 106 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 83645493 Common - putative polysaccharide biosynthesis protein HCH_02717 94 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83644749 Common - hypothetical protein HCH_01926 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 83646700 Common - hypothetical protein HCH_03993 4 None None None 83648157 Common - Restriction endonuclease HCH_05505 96 COG1403 McrA, Restriction endonuclease Defense mechanisms 83644029 Common - predicted sugar epimerase HCH_01162 14 COG4130 COG4130, Predicted sugar epimerase Carbohydrate transport and metabolism 83649057 Common gshA glutamate--cysteine ligase HCH_06422 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 83648768 Common - uncharacterized conserved small protein HCH_06131 5 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 83647337 Common - Adenosine deaminase HCH_04648 147 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 83645585 Common - RecB family exonuclease HCH_02817 51 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 83646557 Common - hypothetical protein HCH_03839 8 None None None 83643692 Common - short chain dehydrogenase HCH_00808 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83644513 Nonpathogen - hypothetical protein HCH_01670 1 None None None 83649439 Common - Transcriptional regulator HCH_06826 129 COG1609 PurR, Transcriptional regulators Transcription 83647034 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_04338 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83647218 Nonpathogen - hypothetical protein HCH_04529 1 None None None 83646191 Nonpathogen - hypothetical protein HCH_03454 1 None None None 83648328 Common - hypothetical protein HCH_05683 9 None None None 83649416 Nonpathogen - hypothetical protein HCH_06802 1 None None None 83648734 Common - Archaeal fructose-1,6-bisphosphatase and related enzyme of inositol monophosphatase family HCH_06096 208 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 83647570 Nonpathogen - hypothetical protein HCH_04889 1 None None None 83645074 Nonpathogen - hypothetical protein HCH_02258 1 None None None 83646578 Common gcvP glycine dehydrogenase HCH_03861 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 83644551 Common rplI ribosomal protein L9 HCH_01713 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 83646019 Common - predicted mannose-6-phosphate isomerase HCH_03272 27 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 83645751 Nonpathogen - hypothetical protein HCH_02992 1 None None None 83645392 Common - Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HCH_02610 64 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83648649 Common - tRNA-dihydrouridine synthase HCH_06009 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 83644175 Common - hypothetical protein HCH_01317 6 None None None 83647540 Common - Transcriptional regulator HCH_04858 192 COG0583 LysR, Transcriptional regulator Transcription 83647827 Common - hypothetical protein HCH_05158 3 None None None 83644501 Common - Cellulase M and related protein HCH_01657 62 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 83646738 Common - Membrane-fusion protein HCH_04033 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83643769 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00887 124 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649389 Common - hypothetical protein HCH_06775 4 None None None 83643475 Common - Transcriptional regulator HCH_00582 75 COG1309 AcrR, Transcriptional regulator Transcription 83642938 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_00026 52 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83644621 Nonpathogen - hypothetical protein HCH_01787 2 None None None 83647068 Common - hypothetical protein HCH_04373 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 83644115 Common lon1 ATP-dependent protease La HCH_01256 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 83648599 Common - hypothetical protein HCH_05958 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 83644772 Common aruG arginine N-succinyltransferase, beta subunit HCH_01949 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 83649001 Nonpathogen - hypothetical protein HCH_06366 1 None None None 83648031 Common - predicted amidophosphoribosyltransferase HCH_05372 171 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 83645589 Nonpathogen - hypothetical protein HCH_02821 1 None None None 83644225 Common - hypothetical protein HCH_01372 5 None None None 83644416 Nonpathogen - hypothetical protein HCH_01569 1 None None None 83646362 Common - predicted Permease HCH_03632 13 COG0730 COG0730, Predicted permeases General function prediction only 83643634 Common - TRAP-type mannitol/chloroaromatic compound transport system, large permease component HCH_00746 124 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 83647730 Nonpathogen - hypothetical protein HCH_05057 1 None None None 83648064 Nonpathogen - hypothetical protein HCH_05405 1 None None None 83644218 Nonpathogen - hypothetical protein HCH_01364 1 None None None 83647102 Common - O-acetylhomoserine sulfhydrylase HCH_04407 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 83649563 Common - Transcriptional regulator HCH_06957 56 COG1309 AcrR, Transcriptional regulator Transcription 83647373 Common - Glycosyltransferase HCH_04684 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83648639 Common - predicted oxidoreductase (related to aryl-alcohol dehydrogenase) HCH_05999 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83644849 Common - short-chain alcohol dehydrogenase-like protein HCH_02025 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83646334 Common - predicted membrane protein involved in D-alanine export HCH_03604 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 83646406 Nonpathogen - hypothetical protein HCH_03675 1 None None None 83645937 Common - hypothetical protein HCH_03184 3 None None None 83644618 Common ung uracil-DNA glycosylase HCH_01784 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 83644842 Nonpathogen - hypothetical protein HCH_02018 1 None None None 83647274 Common - TRAP-type uncharacterized transport system, periplasmic component HCH_04583 89 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 83646707 Common - Nitrate/nitrite transporter HCH_04000 130 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 83644229 Nonpathogen - hypothetical protein HCH_01376 1 None None None 83646207 Common - Serine/threonine protein kinase HCH_03471 103 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83646895 Nonpathogen - hypothetical protein HCH_04198 12 None None None 83643913 Common - Outer membrane protein (porin) HCH_01041 31 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 83644437 Common coxL Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein HCH_01590 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 83644918 Nonpathogen - hypothetical protein HCH_02098 1 None None None 83645826 Common - Transposase and inactivated derivatives HCH_03070 21 None None None 83647345 Common - Methyl-accepting chemotaxis protein HCH_04656 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83644214 Nonpathogen - hypothetical protein HCH_01359 1 None None None 83643336 Common - hypothetical protein HCH_00436 5 COG5544 COG5544, Predicted periplasmic lipoprotein General function prediction only 83648548 Common leuA2 2-isopropylmalate synthase HCH_05908 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83648843 Common rpsQ 30S ribosomal protein S17 HCH_06208 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 83647536 Nonpathogen - hypothetical protein HCH_04853 1 None None None 83648017 Common leuS leucyl-tRNA synthetase HCH_05355 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83644698 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase HCH_01870 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 83648167 Nonpathogen - hypothetical protein HCH_05515 1 None None None 83644102 Common rbfA ribosome-binding factor A HCH_01240 184 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 83644303 Nonpathogen - hypothetical protein HCH_01453 1 None None None 83644109 Common - hypothetical protein HCH_01249 21 None None None 83647121 Common - hypothetical protein HCH_04427 16 None None None 83648632 Common - predicted phosphohydrolase HCH_05992 75 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83648539 Common - Cytochrome b subunit of the bc complex HCH_05899 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 83646541 Common - hypothetical protein HCH_03820 34 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 83646163 Common - hypothetical protein HCH_03425 29 None None None 83644820 Nonpathogen - hypothetical protein HCH_01996 5 None None None 83644464 Nonpathogen - hypothetical protein HCH_01617 1 None None None 83647319 Nonpathogen - hypothetical protein HCH_04630 1 None None None 83643594 Common - Glutamate decarboxylase and related PLP-dependent protein HCH_00706 105 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 83647760 Nonpathogen - hypothetical protein HCH_05089 1 None None None 83647866 Common fleQ transcription regulator FleQ (sigma 54-dependent transcriptional activator) HCH_05199 172 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83644994 Nonpathogen - hypothetical protein HCH_02176 1 None None None 83648625 Common - dinucleoside polyphosphate hydrolase HCH_05984 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 83648938 Common - Membrane protein related to metalloendopeptidase HCH_06301 172 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83648117 Common - ABC-type hemin transport system, ATPase component HCH_05463 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 83648429 Common - collagenase family protein HCH_05788 18 None None None 83648469 Nonpathogen - hypothetical protein HCH_05829 1 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83645185 Common - hypothetical protein HCH_02377 4 None None None 83647462 Nonpathogen - hypothetical protein HCH_04778 1 None None None 83645169 Nonpathogen - hypothetical protein HCH_02357 1 None None None 83648422 Nonpathogen - hypothetical protein HCH_05782 1 None None None 83643762 Nonpathogen - hypothetical protein HCH_00880 1 COG1572 COG1572, Uncharacterized conserved protein Function unknown 83646646 Common gspF general secretion pathway protein F HCH_03936 144 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 83644815 Nonpathogen - hypothetical protein HCH_01992 1 None None None 83646806 Common - predicted ATPase HCH_04105 49 COG4637 COG4637, Predicted ATPase General function prediction only 83647531 Common - uncharacterized protein with SCP/PR1 domains HCH_04848 66 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 83648509 Common - Molybdopterin converting factor, small subunit HCH_05869 58 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 83648893 Common - DnaK suppressor protein HCH_06256 129 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 83649050 Common - Glutathione S-transferase HCH_06415 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83643531 Common - enoyl-CoA hydratase HCH_00640 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83648742 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase HCH_06104 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 83645591 Nonpathogen - hypothetical protein HCH_02823 1 None None None 83645221 Common - Permease of the major facilitator superfamily HCH_02422 84 None None None 83649674 Common atpG2 F0F1 ATP synthase subunit gamma HCH_07072 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 83648530 Common mraW S-adenosyl-methyltransferase MraW HCH_05891 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 83644528 Nonpathogen - hypothetical protein HCH_01687 1 None None None 83645522 Common - FOG: TPR repeat HCH_02747 117 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83642979 Common - putative threonine efflux protein HCH_00068 111 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83645215 Common tatD Mg-dependent DNase HCH_02416 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 83644408 Common - Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases HCH_01561 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 83646513 Common - enterobactin exporter EntS HCH_03791 137 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83648071 Nonpathogen - hypothetical protein HCH_05412 2 None None None 83649468 Common - predicted acetyltransferase and Hydrolase with the alpha/beta hydrolase fold HCH_06860 21 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 83645758 Nonpathogen - hypothetical protein HCH_03000 1 None None None 83645579 Nonpathogen - hypothetical protein HCH_02811 1 None None None 83646124 Common - predicted lipoprotein involved in nitrous oxide reduction HCH_03384 34 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 83643085 Common - protein containing QXW lectin repeats HCH_00177 18 None None None 83646936 Common - predicted acyl esterases HCH_04239 20 COG2936 COG2936, Predicted acyl esterases General function prediction only 83646131 Common - hypothetical protein HCH_03391 12 COG5486 COG5486, Predicted metal-binding integral membrane protein Function unknown 83643042 Nonpathogen - hypothetical protein HCH_00133 1 None None None 83643249 Common zwf glucose-6-phosphate 1-dehydrogenase HCH_00347 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 83647943 Common - Type II secretory pathway, component PulF HCH_05279 143 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 83648869 Common - putative transcriptional regulator HCH_06233 130 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 83644827 Common - predicted Rossmann fold nucleotide-binding protein HCH_02003 125 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 83644731 Common purM Phosphoribosylaminoimidazole (AIR) synthetase HCH_01906 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 83645484 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase HCH_02708 189 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 83645732 Nonpathogen - hypothetical protein HCH_02973 1 None None None 83646762 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04057 9 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648458 Common - Serine/threonine protein kinase HCH_05817 148 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83648642 Nonpathogen - hypothetical protein HCH_06002 1 None None None 83645080 Common - SAM-dependent methyltransferase HCH_02264 47 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83646235 Common - hypothetical protein HCH_03499 8 None None None 83649020 Nonpathogen - hypothetical protein HCH_06384 1 None None None 83646553 Common feoB ferrous iron transport protein B HCH_03835 215 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 83646472 Nonpathogen - hypothetical protein HCH_03749 1 None None None 83646769 Nonpathogen - FOG: TPR repeat HCH_04065 8 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83648525 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase HCH_05886 208 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 83648971 Common istA4 transposase, IS21 family HCH_06335 74 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643045 Nonpathogen - hypothetical protein HCH_00136 1 None None None 83649198 Common - ABC-type Fe3+-hydroxamate transport system, periplasmic component HCH_06571 92 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 83643512 Common - DNA repair protein HCH_00620 173 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83649391 Common - probable phage protein HCH_06777 8 None None None 83643378 Common - maltose/maltodextrin transporter ATP-binding protein HCH_00479 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83644858 Nonpathogen - predicted membrane protein HCH_02035 2 COG4392 COG4392, Predicted membrane protein Function unknown 83648761 Common - 2-oxoisovalerate dehydrogenase HCH_06123 158 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 83648560 Common - hypothetical protein HCH_05919 161 COG1496 COG1496, Uncharacterized conserved protein Function unknown 83644723 Nonpathogen - hypothetical protein HCH_01898 1 None None None 83643721 Common - Metal-dependent Hydrolase of the beta-lactamase superfamily III HCH_00838 73 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 83649240 Common - short chain dehydrogenase HCH_06616 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83649348 Common - Lactoylglutathione lyase HCH_06732 14 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83643022 Common - hypothetical protein HCH_00111 5 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83648998 Common - Coproporphyrinogen III oxidase and related Fe-S oxidoreductase HCH_06363 209 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 83645501 Common - Protein-tyrosine-phosphatase HCH_02726 82 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83645011 Common - hypothetical protein HCH_02194 53 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 83647369 Common gumB Periplasmic protein involved in polysaccharide export HCH_04680 109 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83643298 Common - phage portal protein, PBSX family HCH_00397 24 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 83647252 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_04561 6 COG5628 COG5628, Predicted acetyltransferase General function prediction only 83645745 Common - Glutathione S-transferase HCH_02986 76 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83647902 Common - Ribonuclease HII HCH_05237 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 83648553 Common - putative sulfite oxidase subunit YedY HCH_05912 114 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 83646538 Nonpathogen - hypothetical protein HCH_03816 1 None None None 83646661 Nonpathogen - hypothetical protein HCH_03952 1 None None None 83644322 Common - ABC-type spermidine/putrescine transport system, permease component II HCH_01474 208 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 83646108 Common napB Nitrate reductase cytochrome c-type subunit HCH_03366 39 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 83649111 Nonpathogen - hypothetical protein HCH_06480 1 None None None 83645018 Common dnaE2 DNA polymerase III, alpha subunit HCH_02200 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 83644014 Common - Transcriptional regulator HCH_01147 133 COG1309 AcrR, Transcriptional regulator Transcription 83644424 Common - hypothetical protein HCH_01577 75 COG2013 COG2013, Uncharacterized conserved protein Function unknown 83643494 Nonpathogen - probable integral membrane protein (DUF6) HCH_00602 2 None None None 83645443 Nonpathogen - hypothetical protein HCH_02665 1 None None None 83645089 Common ccoQ cytochrome c oxidase, cbb3-type, subunit CcoQ HCH_02274 22 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 83645061 Nonpathogen - hypothetical protein HCH_02244 1 None None None 83648054 Common - hypothetical protein HCH_05395 6 None None None 83648916 Common - hypothetical protein HCH_06279 12 None None None 83645699 Common - hypothetical protein HCH_02937 15 COG4430 COG4430, Uncharacterized protein conserved in bacteria Function unknown 83648871 Common istB3 IstB helper protein, IS21 family HCH_06235 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 83643369 Nonpathogen - hypothetical protein HCH_00469 1 None None None 83645634 Nonpathogen - hypothetical protein HCH_02868 2 COG3645 COG3645, Uncharacterized phage-encoded protein Function unknown 83649627 Common - Transcriptional regulator HCH_07022 161 COG0583 LysR, Transcriptional regulator Transcription 83644655 Nonpathogen - hypothetical protein HCH_01826 1 None None None 83647972 Common - predicted transcriptional regulator, BolA superfamily HCH_05308 79 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 83643125 Nonpathogen - hypothetical protein HCH_00220 1 None None None 83649103 Common cobK Precorrin-6x reductase HCH_06470 72 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 83644252 Common - thiamine pyrophosphate-requiring enzyme HCH_01399 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83648399 Common - hypothetical protein HCH_05758 16 COG2378 COG2378, Predicted transcriptional regulator Transcription 83646602 Nonpathogen - hypothetical protein HCH_03886 1 None None None 83648030 Common bioB biotin synthase HCH_05371 173 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 83647979 Common - Low specificity phosphatase (HAD superfamily) HCH_05316 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 83645930 Nonpathogen - hypothetical protein HCH_03177 1 None None None 83649163 Nonpathogen - hypothetical protein HCH_06534 1 None None None 83644479 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase HCH_01633 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83647175 Common flgC flagellar basal body rod protein FlgC HCH_04481 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 83644383 Common tkt transketolase HCH_01535 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 83643221 Common - Glutamate dehydrogenase/leucine dehydrogenase HCH_00319 146 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 83643302 Common - putative exonuclease HCH_00401 172 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83643482 Common - Acyl-CoA-binding protein HCH_00589 21 COG4281 ACB, Acyl-CoA-binding protein Lipid metabolism 83648316 Common - hypothetical protein HCH_05671 7 None None None 83644028 Nonpathogen - hypothetical protein HCH_01161 1 None None None 83649493 Common - SAM-dependent methyltransferase HCH_06884 64 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83647187 Nonpathogen - hypothetical protein HCH_04494 2 None None None 83643489 Common - uncharacterized protein conserved in bacteria, prophage-related HCH_00596 6 None None None 83647520 Common - UDP-N-acetylglucosamine 2-epimerase HCH_04836 57 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 83649213 Common - hypothetical protein HCH_06586 10 COG4298 COG4298, Uncharacterized protein conserved in bacteria Function unknown 83648343 Common - hypothetical protein HCH_05697 20 None None None 83648501 Common - hypothetical protein HCH_05860 4 None None None 83644571 Common moeB molybdopterin biosynthesis protein MoeB HCH_01736 221 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 83648337 Common - hypothetical protein HCH_05691 19 None None None 83644063 Nonpathogen - hypothetical protein HCH_01200 1 None None None 83645182 Common - hypothetical protein HCH_02374 5 None None None 83649514 Common - ABC-type sugar transport system, ATPase components HCH_06906 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83643699 Common - predicted Hydrolase of HD superfamily HCH_00816 45 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 83643080 Nonpathogen - hypothetical protein HCH_00171 1 None None None 83647933 Common - polysaccharide biosynthesis protein HCH_05269 45 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83646129 Common - Regulator of nitric oxide reductase transcription HCH_03389 72 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 83642993 Nonpathogen - hypothetical protein HCH_00082 1 None None None 83645228 Common leuB 3-isopropylmalate dehydrogenase HCH_02430 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 83647694 Nonpathogen - hypothetical protein HCH_05019 6 None None None 83649029 Common - dGTP triphosphohydrolase HCH_06393 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 83642997 Common - Cellobiohydrolase A (1,4-beta-cellobiosidase A) HCH_00086 72 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 83646461 Common - hypothetical protein HCH_03737 2 None None None 161897894 Common - tryptophanyl-tRNA synthetase HCH_04739 232 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83645160 Common - Peptidylarginine deiminase and related enzyme HCH_02347 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 83647296 Nonpathogen - hypothetical protein HCH_04605 1 None None None 83644755 Nonpathogen - hypothetical protein HCH_01932 1 None None None 83647846 Common fliP flagellar biosynthesis protein FliP HCH_05178 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 83648096 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05442 8 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645116 Common - 3-methyladenine DNA glycosylase HCH_02303 19 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 83645371 Nonpathogen - hypothetical protein HCH_02588 1 None None None 83646388 Common - SAM-dependent methyltransferase HCH_03658 192 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83647743 Common - predicted symporter HCH_05070 169 COG4147 DhlC, Predicted symporter General function prediction only 83648966 Common - SAM-dependent methyltransferase HCH_06330 33 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83646155 Common - hypothetical protein HCH_03417 15 COG5017 COG5017, Uncharacterized conserved protein Function unknown 83642986 Common hypF [NiFe] hydrogenase maturation protein HypF HCH_00075 109 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83646451 Common - predicted transcriptional regulator HCH_03726 137 COG1733 COG1733, Predicted transcriptional regulators Transcription 83646560 Nonpathogen - hypothetical protein HCH_03842 1 None None None 83646101 Nonpathogen - hypothetical protein HCH_03357 1 None None None 83648043 Common miaA2 tRNA delta(2)-isopentenylpyrophosphate transferase HCH_05384 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 83643360 Nonpathogen - hypothetical protein HCH_00460 1 None None None 83646679 Common - Protein required for attachment to host cells HCH_03970 17 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 83648451 Common - ABC-type polar amino acid transport system, ATPase component HCH_05810 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 83645178 Nonpathogen - hypothetical protein HCH_02370 1 None None None 83645692 Common - Transcriptional regulator HCH_02930 34 COG1309 AcrR, Transcriptional regulator Transcription 83648558 Nonpathogen - hypothetical protein HCH_05917 2 None None None 83647792 Common - Type III secretory pathway, lipoprotein EscJ HCH_05122 49 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 83648780 Common - hypothetical protein HCH_06142 14 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 83645362 Common - Guanosine polyphosphate pyrophosphohydrolase/synthetases HCH_02572 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 83643600 Common - predicted transcriptional regulator HCH_00712 120 COG1733 COG1733, Predicted transcriptional regulators Transcription 83648590 Nonpathogen - hypothetical protein HCH_05949 1 None None None 83646371 Common dapF2 diaminopimelate epimerase HCH_03641 134 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 83643614 Nonpathogen - hypothetical protein HCH_00726 1 None None None 83644644 Common - inactive metal-dependent protease-like protein HCH_01815 180 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 83645036 Common - Outer membrane protein HCH_02219 142 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 83648333 Common - hypothetical protein HCH_05687 5 None None None 83643274 Common - hypothetical protein HCH_00373 13 None None None 83646213 Nonpathogen - hypothetical protein HCH_03477 4 None None None 83643572 Nonpathogen - hypothetical protein HCH_00682 2 None None None 83644797 Nonpathogen - hypothetical protein HCH_01974 1 None None None 83642915 Common dnaA chromosomal replication initiation protein HCH_00002 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 83648750 Common rpe ribulose-phosphate 3-epimerase HCH_06112 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 83647249 Nonpathogen - hypothetical protein HCH_04559 1 None None None 83647556 Common - Methyl-accepting chemotaxis protein HCH_04875 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83645927 Common - probable transcriptional regulator HCH_03174 80 COG3710 CadC, DNA-binding winged-HTH domains Transcription 83643725 Common - Transposase and inactivated derivatives HCH_00841 33 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643113 Common - AraC-type DNA-binding domain-containing protein HCH_00207 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646821 Nonpathogen - hypothetical protein HCH_04121 2 None None None 83643814 Common - TRAP-type uncharacterized transport system, fused permease components HCH_00934 133 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 83649315 Common - hypothetical protein HCH_06696 6 None None None 83643347 Common - DnaK suppressor protein HCH_00447 108 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 83645878 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_03124 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83647673 Common - Peroxiredoxin HCH_04994 226 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83647280 Common - hypothetical protein HCH_04589 25 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 83649651 Common - hypothetical protein HCH_07046 18 COG0433 COG0433, Predicted ATPase General function prediction only 83646444 Common - hypothetical protein HCH_03718 10 None None None 83648023 Common - Acyl-CoA dehydrogenase HCH_05361 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83648631 Common - predicted esterase HCH_05991 47 COG3150 COG3150, Predicted esterase General function prediction only 83649350 Common - predicted transcriptional regulator HCH_06734 141 COG0789 SoxR, Predicted transcriptional regulators Transcription 83649397 Nonpathogen - hypothetical protein HCH_06783 2 None None None 83646882 Nonpathogen - hypothetical protein HCH_04185 1 None None None 83648723 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_06085 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83647109 Common - Cytochrome c553 HCH_04415 67 COG2863 COG2863, Cytochrome c553 Energy production and conversion 83645547 Nonpathogen - Transglutaminase-like enzyme, putative cysteine protease HCH_02774 5 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83646346 Nonpathogen - hypothetical protein HCH_03616 1 None None None 83645793 Nonpathogen - hypothetical protein HCH_03037 3 None None None 83647046 Common - NADPH:quinone reductase and related Zn-dependent oxidoreductase HCH_04350 161 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83645805 Common - hypothetical protein HCH_03049 3 None None None 83647466 Common - Gamma-aminobutyrate permease and related Permease HCH_04782 6 None None None 83643565 Common - predicted Zn-dependent protease HCH_00675 40 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 83647491 Common - hypothetical protein HCH_04807 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 83646995 Common - hypothetical protein HCH_04298 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 83643240 Common - Cyclopropane fatty acid synthase and related methyltransferase HCH_00338 124 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83648092 Common - hypothetical protein HCH_05437 14 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 83646253 Nonpathogen - hypothetical protein HCH_03518 1 None None None 83648104 Nonpathogen - hypothetical protein HCH_05449 1 None None None 83647325 Nonpathogen - hypothetical protein HCH_04636 1 None None None 83647489 Common - Transcriptional regulator HCH_04805 174 COG0583 LysR, Transcriptional regulator Transcription 83642943 Common def peptide deformylase HCH_00030 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 83643309 Common - Protein chain release factor B HCH_00408 114 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 83644903 Nonpathogen - hypothetical protein HCH_02082 1 None None None 83645595 Common - Chromate transport protein ChrA HCH_02827 111 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 83644779 Common pbpC penicillin-binding protein 1C HCH_01956 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 83648989 Common - predicted enzyme with a TIM-barrel fold HCH_06353 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 83649110 Common cobM precorrin-4 C11-methyltransferase HCH_06479 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 83647424 Common - 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases HCH_04736 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 83648233 Nonpathogen - hypothetical protein HCH_05584 1 None None None 83646023 Common - YopN chaperone SycN-like protein HCH_03276 3 None None None 83648982 Common - Collagenase and related protease HCH_06346 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 83643994 Common - hypothetical protein HCH_01126 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 83643677 Nonpathogen - hypothetical protein HCH_00792 1 None None None 83645855 Nonpathogen - hypothetical protein HCH_03099 1 None None None 83644786 Common - ABC-type multidrug transport system, permease component HCH_01963 145 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 83645489 Common - UDP-N-acetyl-D-mannosaminuronate dehydrogenase HCH_02713 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 83649487 Common - putative Zn-dependent protease, contains TPR repeats HCH_06879 129 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 83646099 Common - Chemotaxis protein CheC, inhibitor of MCP methylation HCH_03355 15 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 83644706 Common - group II intron-encoding maturase HCH_01879 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83649644 Nonpathogen - hypothetical protein HCH_07039 1 None None None 83645460 Nonpathogen - hypothetical protein HCH_02682 3 None None None 83648902 Common panC pantoate--beta-alanine ligase HCH_06265 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 83645781 Common - hypothetical protein HCH_03025 92 COG1262 COG1262, Uncharacterized conserved protein Function unknown 83647910 Common - predicted membrane-associated Zn-dependent protease 1 HCH_05245 213 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 83645331 Nonpathogen - hypothetical protein HCH_02540 1 None None None 83645243 Common lolA outer-membrane lipoprotein carrier protein HCH_02446 83 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 83646775 Common flgD1 Flagellar hook capping protein HCH_04072 84 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 83646976 Common - hypothetical protein HCH_04279 9 None None None 83645272 Nonpathogen - hypothetical protein HCH_02476 7 None None None 83645467 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E HCH_02689 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 83645613 Common - Acyl-CoA dehydrogenase HCH_02846 141 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83644123 Common - Membrane-fusion protein HCH_01264 157 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83647438 Common - 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase HCH_04751 188 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 83644444 Common - Sterol desaturase HCH_01597 73 COG3000 ERG3, Sterol desaturase Lipid metabolism 83649256 Common - Glutathione S-transferase HCH_06632 87 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83643432 Common - Fe2+/Zn2+ uptake regulation protein HCH_00537 122 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83646240 Common map1 methionine aminopeptidase HCH_03504 240 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 83647686 Nonpathogen - hypothetical protein HCH_05011 1 None None None 83645687 Common - ABC-type sugar transport system, periplasmic component HCH_02923 16 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83646075 Nonpathogen - hypothetical protein HCH_03331 1 None None None 83645611 Common - hypothetical protein HCH_02844 8 None None None 83648069 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components HCH_05410 52 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 83643784 Common - hypothetical protein HCH_00903 8 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 83644195 Nonpathogen - hypothetical protein HCH_01338 2 None None None 83646926 Nonpathogen - hypothetical protein HCH_04229 2 None None None 83646587 Common - hypothetical protein HCH_03870 12 None None None 83643064 Common - RNA-binding protein (RRM domain) HCH_00155 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 83643527 Common - Serine/threonine protein kinase HCH_00636 166 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83645955 Common - hypothetical protein HCH_03204 41 COG3832 COG3832, Uncharacterized conserved protein Function unknown 83645202 Common - UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase HCH_02401 166 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 83643098 Nonpathogen - hypothetical protein HCH_00191 2 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 83645643 Nonpathogen - hypothetical protein HCH_02876 1 COG2932 COG2932, Predicted transcriptional regulator Transcription 83648271 Nonpathogen - hypothetical protein HCH_05623 1 None None None 83647008 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_04311 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83649356 Common - hypothetical protein HCH_06741 6 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 83643396 Common - Methyl-accepting chemotaxis protein HCH_00498 136 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647525 Common - predicted Fe-S oxidoreductase HCH_04841 50 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83643455 Common pckA phosphoenolpyruvate carboxykinase HCH_00561 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 83646864 Common - predicted membrane protein involved in D-alanine export HCH_04167 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 83645977 Nonpathogen - hypothetical protein HCH_03225 1 None None None 83643034 Common - Endonuclease I HCH_00124 42 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 83644040 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase HCH_01174 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 83643100 Common - hypothetical protein HCH_00193 7 None None None 83648846 Common rpsC 30S ribosomal protein S3 HCH_06211 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 83649068 Common - TRAP-type C4-dicarboxylate transport system, small permease component HCH_06433 23 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 83643279 Common - hypothetical protein HCH_00378 10 None None None 83643067 Common recQ ATP-dependent DNA helicase RecQ HCH_00158 228 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 83644808 Common - hypothetical protein HCH_01985 107 COG0393 COG0393, Uncharacterized conserved protein Function unknown 83644894 Common - Rhs family protein HCH_02073 131 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83643007 Common - hypothetical protein HCH_00096 63 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 83648134 Common - Transcriptional regulator HCH_05481 97 COG1309 AcrR, Transcriptional regulator Transcription 83643972 Common - ABC-type uncharacterized transport system, permease component HCH_01102 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 83644578 Common minE cell division topological specificity factor MinE HCH_01742 83 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 83644851 Common - predicted thioesterase involved in non-ribosomal peptide biosynthesis HCH_02027 51 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83644836 Nonpathogen - hypothetical protein HCH_02012 1 None None None 83649189 Common - hypothetical protein HCH_06562 3 None None None 83644584 Common phaC Poly(3-hydroxyalkanoate) synthetase HCH_01749 76 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 83643176 Common - HD-GYP domain HCH_00273 125 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 83644667 Nonpathogen - hypothetical protein HCH_01839 1 None None None 83648671 Common - 7-keto-8-aminopelargonate synthetase and related enzyme HCH_06031 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83643553 Common - hypothetical protein HCH_00662 22 None None None 83647247 Common - phage terminase, small subunit, putative, P27 family HCH_04557 25 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 83648379 Common - Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases HCH_05736 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 83643147 Nonpathogen - hypothetical protein HCH_00242 1 None None None 83643625 Common - HD-GYP domain HCH_00737 128 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 83649059 Common - FOG: EAL domain HCH_06424 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645677 Nonpathogen - hypothetical protein HCH_02913 1 None None None 83649301 Nonpathogen - hypothetical protein HCH_06681 1 None None None 83645986 Common - 3-methyladenine DNA glycosylase HCH_03236 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 83643891 Common - Thiol-disulfide isomerase and thioredoxins HCH_01016 70 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83646066 Common - putative esterase/lipase HCH_03321 38 COG1647 COG1647, Esterase/lipase General function prediction only 83649052 Common - anti-RNA polymerase sigma 70 factor HCH_06417 24 COG3160 Rsd, Regulator of sigma D Transcription 83645530 Common - hypothetical protein HCH_02755 20 None None None 83647771 Nonpathogen - hypothetical protein HCH_05100 1 None None None 83648416 Common - TRAP-type C4-dicarboxylate transport system, small permease component HCH_05775 15 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 83648437 Common - 3-polyprenyl-4-hydroxybenzoate decarboxylase HCH_05796 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 83645607 Nonpathogen - hypothetical protein HCH_02839 1 None None None 83649133 Nonpathogen - hypothetical protein HCH_06502 1 None None None 83646733 Common - Signal transduction histidine kinase HCH_04028 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83647751 Common - hypothetical protein HCH_05079 35 COG2898 COG2898, Uncharacterized conserved protein Function unknown 83643842 Common cobT NaMN:DMB phosphoribosyltransferase HCH_00964 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 83645051 Common - Glycosyltransferase involved in cell wall biogenesis HCH_02235 169 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83648098 Common pspA Phage shock protein A (IM30), suppresses sigma54-dependent transcription HCH_05443 77 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 83648516 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase HCH_05876 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 83649529 Common - FOG: PKD repeat HCH_06922 45 COG3291 COG3291, FOG: PKD repeat General function prediction only 83644593 Common - Signal transduction histidine kinase HCH_01758 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643832 Common hmgA Homogentisate 1,2-dioxygenase HCH_00954 50 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 83645902 Nonpathogen - hypothetical protein HCH_03149 1 None None None 83643578 Nonpathogen - hypothetical protein HCH_00689 1 None None None 83644977 Common tig trigger factor HCH_02157 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 83648492 Common - Kef-type K+ transport system, predicted NAD-binding component HCH_05852 41 None None None 83646139 Nonpathogen - hypothetical protein HCH_03399 1 None None None 83646582 Common - FOG: EAL domain HCH_03865 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645871 Common - ABC-type sugar transport system, periplasmic component HCH_03116 77 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83647364 Common - FAD/FMN-containing dehydrogenase HCH_04675 35 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83649384 Common - hypothetical protein HCH_06770 10 None None None 83645658 Common - Bacteriophage tail assembly protein HCH_02894 37 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 83649080 Common - FOG: Ankyrin repeat HCH_06445 113 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 83649615 Nonpathogen - hypothetical protein HCH_07010 1 None None None 83647794 Nonpathogen - hypothetical protein HCH_05125 1 None None None 83648250 Common - Membrane-fusion protein HCH_05602 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83648497 Common thiA Thymidylate synthase HCH_05857 140 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 83648369 Common - probable secreted peptidase HCH_05726 7 None None None 83648980 Nonpathogen - hypothetical protein HCH_06344 1 None None None 83644935 Common - FOG: CheY-like receiver HCH_02116 205 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83647667 Common - Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain HCH_04987 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 83643311 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00410 36 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649680 Common atpI F0F1 ATP synthase subunit I HCH_10033 21 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 83646255 Nonpathogen - hypothetical protein HCH_03520 1 None None None 83646839 Nonpathogen - hypothetical protein HCH_04139 1 None None None 83643540 Nonpathogen - hypothetical protein HCH_00649 3 COG0400 COG0400, Predicted esterase General function prediction only 83644933 Common - Permease of the major facilitator superfamily HCH_02114 163 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83645194 Nonpathogen - hypothetical protein HCH_02390 1 None None None 83649141 Nonpathogen - hypothetical protein HCH_06510 1 None None None 83643882 Nonpathogen - hypothetical protein HCH_01007 1 None None None 83647206 Common - uncharacterized ABC-type transport system, ATPase component HCH_04515 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 83643193 Common - Uroporphyrinogen-III synthase HCH_00290 93 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 83643187 Common trx1 thioredoxin HCH_00284 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 83643362 Common - Chemotaxis protein, stimulates methylation of MCP protein HCH_00462 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 83645266 Common - Ribose/xylose/arabinose/galactoside ABC-type transport system, permease components HCH_02470 116 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83648128 Nonpathogen - hypothetical protein HCH_05475 1 None None None 83645995 Nonpathogen - hypothetical protein HCH_03245 1 None None None 83649610 Common - tRNA nucleotidyltransferase/poly(A) polymerase HCH_07005 19 COG4639 COG4639, Predicted kinase General function prediction only 83645445 Nonpathogen - hypothetical protein HCH_02667 2 None None None 83647085 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_04390 79 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83644188 Nonpathogen - hypothetical protein HCH_01331 1 None None None 83643534 Nonpathogen - hypothetical protein HCH_00643 1 None None None 83643713 Common - predicted phosphatase/phosphohexomutase HCH_00830 171 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 83646425 Common - hypothetical protein HCH_03698 2 None None None 83648877 Common anmK anhydro-N-acetylmuramic acid kinase HCH_06240 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 83647202 Nonpathogen - hypothetical protein HCH_04511 1 None None None 83649552 Common - protein of unknown function (DUF1439) HCH_06945 7 None None None 83643178 Common gap1 glyceraldehyde-3-phosphate dehydrogenase, type I HCH_00275 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 83645000 Common - hypothetical protein HCH_02182 66 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 83647395 Common - Cold shock protein HCH_04707 179 COG1278 CspC, Cold shock proteins Transcription 83649606 Common - predicted thioesterase involved in non-ribosomal peptide biosynthesis HCH_07001 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83646749 Nonpathogen - hypothetical protein HCH_04044 1 None None None 83643130 Common - predicted carboxypeptidase HCH_00225 32 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 83646683 Nonpathogen - hypothetical protein HCH_03974 1 None None None 83648132 Common - Cation/multidrug efflux pump HCH_05479 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83645347 Common - hypothetical protein HCH_02557 16 None None None 83643185 Common - ABC-type branched-chain amino acid transport system, periplasmic component HCH_00282 138 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83648502 Common motB flagellar motor protein MotB HCH_05862 149 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83644834 Common - hypothetical protein HCH_02010 68 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 83646981 Nonpathogen - hypothetical protein HCH_04285 2 None None None 83645328 Common - hypothetical protein HCH_02537 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 83644131 Common aceF pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase HCH_01273 201 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 83646106 Common napD uncharacterized protein involved in formation of periplasmic nitrate reductase HCH_03363 2 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 83644764 Common - predicted membrane protein HCH_01941 40 COG3647 COG3647, Predicted membrane protein Function unknown 83645364 Common - Transposase and inactivated derivatives HCH_02574 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 83648896 Common - Na+/proline symporter HCH_06259 223 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 83649294 Common - predicted metalloprotease HCH_06673 3 COG2321 COG2321, Predicted metalloprotease General function prediction only 83646905 Nonpathogen - hypothetical protein HCH_04208 1 None None None 83647636 Nonpathogen - hypothetical protein HCH_04957 1 None None None 83648987 Common - Tfp pilus assembly protein, ATPase PilU HCH_06351 204 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 83644926 Nonpathogen - hypothetical protein HCH_02107 1 None None None 83645274 Common - Zinc metalloprotease (elastase) HCH_02479 52 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 83647457 Common proS prolyl-tRNA synthetase HCH_04773 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83648262 Common - Transposase and inactivated derivatives HCH_05614 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643223 Common - Fructosamine-3-kinase HCH_00321 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 83649079 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06444 17 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643776 Nonpathogen - protein containing ankyrin repeats HCH_00894 1 None None None 83647112 Common - hypothetical protein HCH_04418 42 COG3391 COG3391, Uncharacterized conserved protein Function unknown 83648477 Common lipB lipoate-protein ligase B HCH_05837 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 83643839 Common - hypothetical protein HCH_00961 2 None None None 83645887 Common - putative protein-S-isoprenylcysteine methyltransferase HCH_03133 13 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 83648284 Common istB2 IstB helper protein, IS21 family HCH_05636 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 83643324 Common - putative threonine efflux protein HCH_00424 118 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83644770 Common aruC acetylornithine transaminase HCH_01947 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83645727 Common - Polyketide synthase modules and related protein HCH_02966 236 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83645306 Common - hypothetical protein HCH_02514 5 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 83647954 Common - hypothetical protein HCH_05290 5 None None None 83647964 Common - hypothetical protein HCH_05301 6 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 83648295 Common - hypothetical protein HCH_05647 7 None None None 83647624 Common - uncharacterized protein, possibly involved in aromatic compounds catabolism HCH_04945 26 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83643824 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_00946 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83645122 Common - uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein HCH_02309 107 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 83648318 Common - hypothetical protein HCH_05673 13 None None None 83648259 Common - Transposase and inactivated derivatives HCH_05611 13 None None None 83648687 Nonpathogen - hypothetical protein HCH_06046 1 None None None 83643935 Common - 5-formyltetrahydrofolate cyclo-ligase HCH_01064 165 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 83648341 Common - predicted transcriptional regulator HCH_05695 26 COG1396 HipB, Predicted transcriptional regulators Transcription 83648771 Common - cAMP-regulatory protein HCH_06133 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83647894 Common - Molybdopterin converting factor, large subunit HCH_05229 160 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 83648298 Common - hypothetical protein HCH_05650 4 None None None 83644091 Common greA Transcription elongation factor HCH_01229 202 COG0782 GreA, Transcription elongation factor Transcription 83644316 Common - ABC-type sugar transport system, periplasmic component HCH_01468 35 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83647320 Nonpathogen - hypothetical protein HCH_04631 2 None None None 83644991 Nonpathogen - hypothetical protein HCH_02173 1 None None None 83644396 Common - predicted phosphohydrolase HCH_01549 102 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 83643217 Common - Thiol-disulfide isomerase and thioredoxins HCH_00315 66 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83649232 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06608 30 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643417 Common - predicted sulfurtransferase HCH_00522 113 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 83647984 Common - Ribosome-associated protein Y (PSrp-1) HCH_05322 127 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 83643391 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_00494 185 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645157 Common trxB1 thioredoxin-disulfide reductase HCH_02344 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 83646622 Common - putative threonine efflux protein HCH_03910 122 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83648724 Common - predicted membrane protein HCH_06086 133 COG2860 COG2860, Predicted membrane protein Function unknown 83643152 Nonpathogen - hypothetical protein HCH_00247 1 None None None 83647231 Common - hypothetical protein HCH_04541 3 None None None 83648657 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_06017 49 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83645475 Common - hypothetical protein HCH_02698 54 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 83644000 Common - AraC-type DNA-binding domain-containing protein HCH_01132 59 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645407 Common - hypothetical protein HCH_02627 18 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 83647613 Common - hypothetical protein HCH_04934 9 None None None 83646773 Nonpathogen - flagellar motor switch protein FliM-like protein HCH_04070 1 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 83643180 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00277 4 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648228 Common - Adenosine deaminase HCH_05579 193 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 83644792 Common - Rhs family protein HCH_01969 74 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83644660 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component HCH_01831 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83647050 Common - Signal transduction histidine kinase HCH_04354 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83645107 Nonpathogen - hypothetical protein HCH_02294 1 None None None 83646287 Nonpathogen - hypothetical protein HCH_03555 1 None None None 83646316 Common - putative multicopper oxidases HCH_03584 59 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 83647496 Common - hypothetical protein HCH_04812 14 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 83645880 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_03126 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83649545 Common - Acyl dehydratase HCH_06938 27 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83643425 Nonpathogen - hypothetical protein HCH_00531 1 None None None 83647011 Nonpathogen - predicted transcriptional regulator HCH_04314 2 None None None 83643316 Common - TRAP-type mannitol/chloroaromatic compound transport system, small permease component HCH_00416 71 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 83643518 Common - FOG: GGDEF domain HCH_00626 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83649363 Nonpathogen - hypothetical protein HCH_06748 1 None None None 83643584 Common - Signal transduction histidine kinase HCH_00695 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643666 Common - hypothetical protein HCH_00780 5 None None None 83646060 Common - 4-aminobutyrate aminotransferase and related aminotransferase HCH_03315 22 None None None 83648249 Common - Cation/multidrug efflux pump HCH_05601 180 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83648370 Common - hypothetical protein HCH_05727 9 None None None 83645768 Nonpathogen - hypothetical protein HCH_03010 1 None None None 83644231 Common - Transposase and inactivated derivatives HCH_01378 54 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 83645046 Common - SAM-dependent methyltransferase HCH_02229 112 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83644164 Nonpathogen - hypothetical protein HCH_01307 1 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 83647639 Common - hypothetical protein HCH_04960 9 None None None 83643875 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_01000 174 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83647783 Common yscS Type III secretory pathway, component EscS HCH_05112 66 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 83649074 Common - Phosphomannomutase HCH_06439 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 83647123 Nonpathogen - hypothetical protein HCH_04430 1 None None None 83649031 Common - Site-specific recombinase HCH_06395 121 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 83645399 Nonpathogen - hypothetical protein HCH_02619 1 None None None 83648174 Common - Coenzyme F390 synthetase HCH_05522 28 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 83644799 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_01976 14 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83647412 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_04724 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83648638 Common - Glycerol-3-phosphate dehydrogenase HCH_05998 4 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83645915 Common - NAD-dependent aldehyde dehydrogenase HCH_03162 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83649100 Common cobO cob(I)alamin adenosyltransferase HCH_06467 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 83645402 Common cysK cysteine synthase A HCH_02622 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83643856 Common - predicted proteasome-type protease HCH_00979 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 83647757 Common - glycerol-3-phosphate acyltransferase HCH_05086 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 83647498 Common rdgC recombination associated protein HCH_04814 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 83643335 Common - predicted oxidoreductase HCH_00435 184 COG4989 COG4989, Predicted oxidoreductase General function prediction only 83643764 Common - Rad3-related DNA helicase HCH_00882 62 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 83648943 Common - hypothetical protein HCH_06306 17 None None None 83648242 Common - Na+/alanine symporter HCH_05593 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 83645980 Common - hypothetical protein HCH_03230 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 83649591 Common nagA N-acetylglucosamine-6-phosphate deacetylase HCH_06986 122 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 83647713 Common - hypothetical protein HCH_05040 22 None None None 83643359 Common - Chemotaxis signal transduction protein HCH_00459 123 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83649178 Common - hypothetical protein HCH_06549 56 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83647884 Common - Signal transduction histidine kinase HCH_05218 226 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83646525 Common - Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster HCH_03804 125 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 83643445 Common - predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) HCH_00551 158 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 83646705 Nonpathogen - hypothetical protein HCH_03998 1 None None None 83647603 Common ruvC crossover junction endodeoxyribonuclease RuvC HCH_04924 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 83649168 Common - FOG: TPR repeat, SEL1 subfamily HCH_06539 20 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 83644055 Common - Transcriptional regulator HCH_01190 117 COG0583 LysR, Transcriptional regulator Transcription 83647073 Nonpathogen - hypothetical protein HCH_04378 2 None None None 83647961 Nonpathogen - hypothetical protein HCH_05298 1 None None None 83644430 Common - hypothetical protein HCH_01583 75 COG2013 COG2013, Uncharacterized conserved protein Function unknown 83647837 Common - Chemotaxis protein HCH_05169 44 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647889 Nonpathogen - hypothetical protein HCH_05224 1 None None None 83647767 Common - hypothetical protein HCH_05096 3 None None None 83648463 Common - Anaerobic dehydrogenase, typically selenocysteine-containing HCH_05823 193 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 83646197 Common - Outer membrane receptor protein, mostly Fe transport HCH_03460 71 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83643732 Common - Transcriptional regulator HCH_00849 63 COG1309 AcrR, Transcriptional regulator Transcription 83644246 Common - Sugar kinase, ribokinase family HCH_01393 154 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83644986 Common - Long-chain fatty acid transport protein HCH_02167 49 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 83648169 Nonpathogen - hypothetical protein HCH_05517 1 None None None 83648755 Common - ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain HCH_06117 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 83649565 Common trpA2 tryptophan synthase, alpha subunit HCH_06959 215 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 83645287 Nonpathogen - hypothetical protein HCH_02493 1 None None None 83649223 Common - Kef-type K+ transport system, predicted NAD-binding component HCH_06598 67 None None None 83647565 Common - Multiple antibiotic transporter HCH_04884 155 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 83646059 Common - VWA_CoxE family protein HCH_03314 25 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 83648360 Common - hypothetical protein HCH_05715 29 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 83643502 Nonpathogen - protein containing tetratricopeptide repeats (TPR1, TPR2) HCH_00609 1 None None None 83647475 Common - N-acetyl-beta-hexosaminidase HCH_04791 49 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 83646875 Common - hypothetical protein HCH_04178 9 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 83646891 Common - probable acyltransferase HCH_04194 19 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83648141 Common arcC carbamate kinase HCH_05488 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 83648257 Nonpathogen - hypothetical protein HCH_05609 1 None None None 83643210 Common - hypothetical protein HCH_00308 23 None None None 83643705 Nonpathogen - hypothetical protein HCH_00821 1 None None None 83647510 Common hisH2 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit HCH_04826 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 83649311 Common - Diadenosine tetraphosphatase and related serine/threonine protein phosphatase HCH_06690 30 None None None 83645098 Common - hypothetical protein HCH_02284 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 83646317 Common - Transcriptional regulator HCH_03585 72 COG1846 MarR, Transcriptional regulators Transcription 83648583 Common rplU ribosomal protein L21 HCH_05941 208 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 83643115 Common - Signal transduction histidine kinase HCH_00209 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644864 Nonpathogen cdsA CDP-diglyceride synthetase HCH_02040 28 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 83649043 Common - DNA-binding ferritin-like protein (oxidative damage protectant) HCH_06408 102 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 83649262 Common - Transcriptional regulator HCH_06639 145 COG0583 LysR, Transcriptional regulator Transcription 83648693 Common - hypothetical protein HCH_06053 10 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 83646658 Common - acetyl-CoA synthetase HCH_03948 203 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 83643017 Common - Coenzyme F420-reducing hydrogenase, gamma subunit HCH_00106 47 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 83646834 Nonpathogen - hypothetical protein HCH_04134 1 None None None 83643201 Common - hypothetical protein HCH_00299 56 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 83645453 Nonpathogen - hypothetical protein HCH_02675 1 None None None 83648013 Common - putative Mg2+ and Co2+ transporter CorC HCH_05351 217 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 83643950 Common ubiB 2-polyprenylphenol 6-hydroxylase HCH_01080 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83647474 Common - hypothetical protein HCH_04790 52 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 83645058 Nonpathogen - hypothetical protein HCH_02242 1 None None None 83643918 Common rfaF lipopolysaccharide heptosyltransferase II HCH_01046 102 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 83644616 Common prfB peptide chain release factor 2 HCH_01782 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 83644373 Common - protein of unknown function (DUF748) HCH_01525 44 None None None 83644350 Common - hypothetical protein HCH_01502 94 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 83643039 Common - RNA:NAD 2'-phosphotransferase HCH_00129 42 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 83643927 Common rfaQ lipopolysaccharide heptosyltransferase III, putative HCH_01054 114 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 83644716 Common rnfG predicted NADH:ubiquinone oxidoreductase, subunit RnfG HCH_01889 61 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 83648190 Nonpathogen - hypothetical protein HCH_05539 1 None None None 83643401 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00504 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83646817 Common - Carbonic anhydrase HCH_04117 154 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 83648475 Common - predicted unusual protein kinase HCH_05835 170 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83647353 Common - ABC-type multidrug transport system, ATPase component HCH_04664 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83648791 Common - hypothetical protein HCH_06155 14 None None None 83645970 Nonpathogen - hypothetical protein HCH_03219 1 None None None 83647705 Common - Transposase and inactivated derivatives HCH_05032 6 None None None 83645317 Common - Zn-dependent Hydrolase, including glyoxylases HCH_02525 198 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83647016 Common - Na+-driven multidrug efflux pump HCH_04319 123 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83645567 Common - aromatic amino acid aminotransferase HCH_02799 74 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83648957 Common - Glutamine synthetase HCH_06321 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83647809 Nonpathogen - hypothetical protein HCH_05139 1 None None None 83644342 Nonpathogen - hypothetical protein HCH_01494 1 None None None 83643744 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00862 220 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83648828 Common rpsD ribosomal protein S4 HCH_06194 233 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 83647228 Nonpathogen - hypothetical protein HCH_04538 1 None None None 83648602 Common - hypothetical protein HCH_05961 16 None None None 83646958 Common - predicted acetyltransferase and Hydrolase with the alpha/beta hydrolase fold HCH_04261 20 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 83645563 Common thrS1 Threonyl-tRNA synthetase HCH_02794 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83646918 Nonpathogen - hypothetical protein HCH_04221 1 None None None 83647221 Nonpathogen - hypothetical protein HCH_04531 3 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 83648313 Common - hypothetical protein HCH_05666 11 None None None 83645557 Common - Serine/threonine protein kinase HCH_02787 119 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83648776 Common - Phosphoribulokinase HCH_06138 53 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 83648778 Common - hypothetical protein HCH_06140 66 None None None 83649472 Common - FOG: FHA domain HCH_06864 38 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 83643941 Common - Xaa-Pro aminopeptidase HCH_01070 240 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 83646673 Common - hypothetical protein HCH_03964 50 COG0398 COG0398, Uncharacterized conserved protein Function unknown 83649208 Nonpathogen - hypothetical protein HCH_06581 1 None None None 83648835 Common rpsE 30S ribosomal protein S5 HCH_06199 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 83644096 Common glmM phosphoglucosamine mutase HCH_01234 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 83646941 Common - FOG: TPR repeat, SEL1 subfamily HCH_04244 98 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 83645007 Common - hypothetical protein HCH_02189 55 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 83645280 Nonpathogen - hypothetical protein HCH_02487 1 None None None 83643232 Common - predicted Permease HCH_00330 95 COG2962 RarD, Predicted permeases General function prediction only 83644604 Common - ABC-type uncharacterized transport system, permease component HCH_01769 54 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 83647830 Common - Chemotaxis signal transduction protein HCH_05161 139 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83647596 Common tolB translocation protein TolB HCH_04915 170 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 83645834 Nonpathogen - hypothetical protein HCH_03078 3 None None None 83648420 Common - Na+/H+ antiporter NhaD and related arsenite Permease HCH_05779 35 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 83644956 Common - predicted phosphatase HCH_02137 181 COG0546 Gph, Predicted phosphatases General function prediction only 83648199 Nonpathogen - hypothetical protein HCH_05550 1 None None None 83645290 Common - Enoyl-CoA hydratase/carnithine racemase HCH_02498 163 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83645836 Common - predicted HD phosphohydrolase HCH_03080 16 COG4341 COG4341, Predicted HD phosphohydrolase General function prediction only 83642922 Common - hypothetical protein HCH_00009 29 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 83644082 Common smpA Small protein A (tmRNA-binding) HCH_01219 48 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 83647649 Common - hypothetical protein HCH_04969 15 COG0730 COG0730, Predicted permeases General function prediction only 83646220 Common - Polyketide synthase modules and related protein HCH_03484 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83644703 Common - Membrane protein related to metalloendopeptidase HCH_01876 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83647261 Nonpathogen - hypothetical protein HCH_04568 2 None None None 83647005 Common - transcriptional regulator MalT HCH_04308 110 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 83645731 Common - FOG: GGDEF domain HCH_02971 193 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83648213 Common - hypothetical protein HCH_05563 25 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 83649402 Nonpathogen - hypothetical protein HCH_06788 1 None None None 83646174 Common - hypothetical protein HCH_03436 8 None None None 83644281 Nonpathogen - probable calcium-binding protein containing EF hand domain HCH_01430 1 None None None 83649184 Nonpathogen - hypothetical protein HCH_06556 4 None None None 83644159 Common acpD Acyl carrier protein phosphodiesterase HCH_01302 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 83644481 Common - ABC-type Fe3+ transport system, periplasmic component HCH_01635 34 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83644874 Nonpathogen - hypothetical protein HCH_02053 1 None None None 83647690 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_05015 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83646014 Nonpathogen - hypothetical protein HCH_03266 1 None None None 83643670 Common - Flavodoxins HCH_00784 48 COG0716 FldA, Flavodoxins Energy production and conversion 83645641 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain HCH_02875 194 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 83643756 Nonpathogen - hypothetical protein HCH_00874 1 None None None 83649525 Common - Signal transduction histidine kinase HCH_06918 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646911 Common - Preprotein translocase subunit SecD HCH_04214 4 None None None 83647164 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase HCH_04470 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 83648703 Common - hypothetical protein HCH_06064 10 None None None 83646610 Common - Subtilisin-like serine protease HCH_03894 138 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 83646411 Common cadR Cd(II)/Pb(II)-responsive transcriptional regulator HCH_03681 139 COG0789 SoxR, Predicted transcriptional regulators Transcription 83646503 Common - Rhs family protein HCH_03781 57 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83643092 Common - Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family HCH_00185 44 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 83648354 Common - hypothetical protein HCH_05708 12 None None None 83645524 Common - Signal transduction histidine kinase HCH_02749 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643164 Common - predicted membrane protein/domain HCH_00261 20 COG1714 COG1714, Predicted membrane protein/domain Function unknown 83644346 Nonpathogen - hypothetical protein HCH_01498 1 None None None 83645322 Common - Methyl-accepting chemotaxis protein HCH_02530 14 None None None 83645213 Common - ABC-type Zn2+ transport system, periplasmic component/surface adhesin HCH_02413 146 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83643465 Common ftsY signal recognition particle-docking protein FtsY HCH_00572 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 83643632 Common - TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component HCH_00744 109 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83648510 Common moaC molybdenum cofactor biosynthesis protein C HCH_05870 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83645231 Common truA tRNA pseudouridine synthase A HCH_02434 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 83648807 Common - Serine acetyltransferase HCH_06172 200 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83645865 Nonpathogen - hypothetical protein HCH_03109 1 None None None 83646536 Nonpathogen - hypothetical protein HCH_03815 2 None None None 83647118 Common - Cytochrome c, mono- and diheme variants HCH_04424 21 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 83648483 Common - Cell division protein FtsI/penicillin-binding protein 2 HCH_05843 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 83644951 Common - Phosphatidylserine/phosphatidylglycerophosphate/c ardiolipin synthases and related enzyme HCH_02132 146 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 83645518 Common - Di- and tricarboxylate transporters HCH_02743 99 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 83648350 Common - 3-oxoacyl-(acyl-carrier-protein) synthase HCH_05705 10 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83648149 Common clpC ATPase with chaperone activity, ATP-binding subunit HCH_05497 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83648616 Common scfA Malic enzyme HCH_05974 199 COG0281 SfcA, Malic enzyme Energy production and conversion 83646295 Common - hypothetical protein HCH_03563 5 None None None 83648766 Common - Indole-3-glycerol phosphate synthase HCH_06128 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 83646522 Nonpathogen - hypothetical protein HCH_03800 1 None None None 83647930 Common neuB Sialic acid synthase HCH_05266 80 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 83648427 Common - hypothetical protein HCH_05786 163 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83646729 Common - predicted Co/Zn/Cd cation transporters HCH_04023 83 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 83646480 Nonpathogen - hypothetical protein HCH_03758 1 None None None 83648609 Common aroK shikimate kinase HCH_05968 196 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 83649500 Common - hypothetical protein HCH_06892 12 None None None 83645544 Common - putative cation transport regulator HCH_02771 21 COG4572 ChaB, Putative cation transport regulator General function prediction only 83644504 Nonpathogen - hypothetical protein HCH_01660 1 None None None 83648928 Common - NAD-dependent aldehyde dehydrogenase HCH_06290 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83646351 Common - predicted Fe-S oxidoreductase HCH_03621 73 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83644364 Common deoA thymidine phosphorylase HCH_01516 129 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 83647285 Common - 1-aminocyclopropane-1-carboxylate deaminase HCH_04594 68 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 83649669 Common - Tn7-like transposition protein A HCH_07067 18 None None None 83645799 Common - hypothetical protein HCH_03043 75 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 83643861 Common - hypothetical protein HCH_00984 83 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 83648881 Common - hypothetical protein HCH_06244 21 None None None 83649409 Common - hypothetical protein HCH_06795 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 83644889 Common lexA LexA repressor HCH_02068 172 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 83646112 Nonpathogen - hypothetical protein HCH_03371 1 None None None 83645413 Nonpathogen - hypothetical protein HCH_02634 6 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83645390 Common - predicted rRNA methylase HCH_02608 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 83645133 Nonpathogen - hypothetical protein HCH_02320 1 None None None 83643905 Common ntrC nitrogen regulation protein NR(I) HCH_01033 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83646756 Nonpathogen - hypothetical protein HCH_04051 1 None None None 83649623 Common - putative protein-S-isoprenylcysteine methyltransferase HCH_07018 20 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 83644155 Common - Mannitol-1-phosphate/altronate dehydrogenase HCH_01298 238 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 83642958 Common - Na+-driven multidrug efflux pump HCH_00046 115 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83648798 Common ubiC 4-hydroxybenzoate synthetase (chorismate lyase) HCH_06163 13 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 83647674 Common - short chain dehydrogenase HCH_04995 236 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83648691 Common - hypothetical protein HCH_06050 18 None None None 83643267 Common - hypothetical protein HCH_00365 9 None None None 83648114 Common - putative heme degradation protein HCH_05460 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 83648650 Common fis DNA-binding protein Fis HCH_06010 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 83646494 Nonpathogen - hypothetical protein HCH_03772 1 None None None 83648800 Common - Glycosyltransferase, probably involved in cell wall biogenesis HCH_06165 217 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83645238 Common - uncharacterized membrane protein, required for colicin V production HCH_02441 109 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 83647139 Nonpathogen - hypothetical protein HCH_04445 1 None None None 83643283 Common - probable phage protein HCH_00382 25 COG5283 COG5283, Phage-related tail protein Function unknown 83643583 Nonpathogen - hypothetical protein HCH_00694 1 None None None 83649323 Common accC2 acetyl-CoA carboxylase HCH_06705 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83648121 Nonpathogen - hypothetical protein HCH_05467 1 None None None 83644495 Common - Transcriptional regulator HCH_01651 181 COG0583 LysR, Transcriptional regulator Transcription 83649345 Nonpathogen - uncharacterized protein involved in plasmid maintenance HCH_06729 3 COG5083 SMP2, Uncharacterized protein involved in plasmid maintenance General function prediction only 83646795 Nonpathogen - protein containing tetratricopeptide repeat HCH_04093 4 None None None 83646619 Common - hypothetical protein HCH_03907 2 None None None 83647905 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase HCH_05240 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 83649287 Common - hypothetical protein HCH_06665 16 None None None 83646175 Common - hypothetical protein HCH_03437 3 None None None 83646593 Nonpathogen - hypothetical protein HCH_03876 1 None None None 83645624 Nonpathogen - hypothetical protein HCH_02856 1 None None None 83643120 Nonpathogen - hypothetical protein HCH_00214 10 None None None 83647317 Common - predicted transcriptional regulator HCH_04628 15 COG3655 COG3655, Predicted transcriptional regulator Transcription 83644427 Common - hypothetical protein HCH_01581 7 None None None 83644597 Common argF1 ornithine carbamoyltransferase HCH_01762 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 83647897 Common recA recA protein HCH_05232 220 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 83644916 Nonpathogen - hypothetical protein HCH_02096 1 None None None 83648081 Nonpathogen - hypothetical protein HCH_05424 2 COG2968 COG2968, Uncharacterized conserved protein Function unknown 83648367 Common - hypothetical protein HCH_05724 8 None None None 83643345 Nonpathogen - hypothetical protein HCH_00445 1 None None None 83648634 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_05994 99 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 83648546 Common rimI ribosomal-protein-alanine acetyltransferase HCH_05906 189 COG0456 RimI, Acetyltransferases General function prediction only 83644485 Nonpathogen - hypothetical protein HCH_01640 4 None None None 83647347 Nonpathogen - hypothetical protein HCH_04658 1 None None None 83646161 Common - hypothetical protein HCH_03423 4 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 83645824 Common - Lysophospholipase HCH_03068 66 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83644086 Common dnaK Molecular chaperone HCH_01224 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83644727 Common - hypothetical protein HCH_01902 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 83647981 Common - hypothetical protein HCH_05318 50 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 83649330 Common - Asparaginase HCH_06713 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 83645187 Common - Periplasmic protein involved in polysaccharide export HCH_02380 67 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83643659 Common ubiA 4-hydroxybenzoate polyprenyl transferase HCH_00773 187 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 83648223 Common rnr2 ribonuclease R HCH_05573 200 COG0557 VacB, Exoribonuclease R Transcription 83642941 Common sun sun protein HCH_00028 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 83643922 Common - Glycosyltransferase HCH_01050 227 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83646205 Nonpathogen - hypothetical protein HCH_03468 1 None None None 83646848 Common - uncharacterized protein with SCP/PR1 domains HCH_04148 47 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 83647707 Common - short-chain alcohol dehydrogenase-like protein HCH_05034 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83644840 Common - probable endoglucanase HCH_02016 9 None None None 83643044 Common - hypothetical protein HCH_00135 3 None None None 83647003 Common - Signal transduction histidine kinase HCH_04306 136 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647762 Common - hypothetical protein HCH_05091 2 None None None 83647334 Common - SAM-dependent methyltransferase HCH_04645 14 None None None 83646475 Common - cystine transporter subunit HCH_03752 186 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647501 Common fliS flagellar protein FliS HCH_04817 85 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 83643422 Common folE GTP cyclohydrolase I HCH_00527 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 83644733 Common - Phosphatidylglycerophosphate synthase HCH_01908 201 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 83644735 Common - ParA family protein HCH_01910 207 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83644744 Common - hypothetical protein HCH_01919 21 None None None 83648143 Common arcA arginine deiminase HCH_05490 51 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 83645738 Common - Transcriptional regulator HCH_02979 174 COG0583 LysR, Transcriptional regulator Transcription 83648826 Common rplQ ribosomal protein L17 HCH_06192 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 83646515 Common - iron-enterobactin transporter permease HCH_03793 191 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 83644757 Common - predicted Permease HCH_01934 102 COG0795 COG0795, Predicted permeases General function prediction only 83647864 Common - Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation HCH_05197 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646914 Common - SAM-dependent methyltransferase HCH_04217 11 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83642929 Common fumC fumarate hydratase HCH_00016 223 COG0114 FumC, Fumarase Energy production and conversion 83649101 Common cbiA Cobyrinic acid a,c-diamide synthase HCH_06468 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 83646088 Nonpathogen - hypothetical protein HCH_03344 1 None None None 83646404 Common - hypothetical protein HCH_03674 21 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 83643961 Common - guanine deaminase HCH_01091 161 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83646900 Nonpathogen - hypothetical protein HCH_04203 1 None None None 83647871 Nonpathogen - hypothetical protein HCH_05204 1 None None None 83647213 Common ureC urease subunit alpha HCH_04523 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 83648744 Common - Organic solvent tolerance protein OstA HCH_06106 123 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 83642977 Common - Signal transduction histidine kinase HCH_00065 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83649365 Common - Integrase HCH_06750 155 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83646122 Nonpathogen - hypothetical protein HCH_03382 1 None None None 83645722 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02961 215 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83646841 Nonpathogen - hypothetical protein HCH_04141 1 None None None 83648130 Nonpathogen - hypothetical protein HCH_05477 1 None None None 83649378 Common - phage portal protein, PBSX family HCH_06763 24 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 83646897 Common - hypothetical protein HCH_04201 11 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 83648321 Nonpathogen - hypothetical protein HCH_05676 1 None None None 83646010 Common - Type III secretory pathway, component EscT HCH_03261 123 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 83647448 Common - uncharacterized Fe-S protein HCH_04763 54 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 83644271 Nonpathogen - hypothetical protein HCH_01418 1 None None None 83646543 Common - Outer membrane receptor protein, mostly Fe transport HCH_03822 105 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83646133 Common - predicted transcriptional regulator HCH_03393 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 83647735 Nonpathogen - hypothetical protein HCH_05062 1 None None None 83646584 Common - FOG: TPR repeat HCH_03867 102 COG3710 CadC, DNA-binding winged-HTH domains Transcription 83649173 Nonpathogen - hypothetical protein HCH_06544 1 None None None 83646793 Common fliQ1 flagellar biosynthetic protein FliQ HCH_04091 53 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 83648577 Common mviN integral membrane protein MviN HCH_05935 191 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 83643434 Common - protein containing CheW-like domain HCH_00539 9 None None None 83644462 Common - predicted choline kinase involved in LPS biosynthesis HCH_01615 13 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 83644511 Common - enoyl-CoA hydratase HCH_01668 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83646233 Nonpathogen - hypothetical protein HCH_03497 1 None None None 83648467 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_05827 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83647176 Common flgB flagellar basal body rod protein FlgB HCH_04482 93 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 83647268 Common pheS phenylalanyl-tRNA synthetase, alpha subunit HCH_04575 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 83649190 Nonpathogen - hypothetical protein HCH_06561 1 None None None 83644166 Common - AraC-type DNA-binding domain-containing protein HCH_01309 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645087 Common - Polyferredoxin HCH_02272 78 COG0348 NapH, Polyferredoxin Energy production and conversion 83644146 Common - hypothetical protein HCH_01288 3 None None None 83645216 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_02417 122 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83644389 Common - FOG: CheY-like receiver HCH_01541 118 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 83646244 Nonpathogen - hypothetical protein HCH_03508 1 None None None 83643047 Common thiO thiamine biosynthesis protein ThiO HCH_00138 85 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83644076 Common - Outer membrane protein HCH_01213 116 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83644681 Common - hypothetical protein HCH_01854 9 None None None 83643376 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_00477 89 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83645811 Nonpathogen - hypothetical protein HCH_03055 1 None None None 83646474 Nonpathogen - hypothetical protein HCH_03751 1 None None None 83646764 Nonpathogen - hypothetical protein HCH_04059 1 None None None 83644477 Nonpathogen - hypothetical protein HCH_01631 1 None None None 83647155 Common - Cysteine sulfinate desulfinase/cysteine desulfurase and related enzyme HCH_04461 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 83645252 Nonpathogen - hypothetical protein HCH_02456 1 None None None 83648695 Common - ABC-type multidrug transport system, ATPase and permease components HCH_06055 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83648782 Common - Type II secretory pathway, pseudopilin PulG HCH_06144 7 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 83643276 Common - Bacterial nucleoid DNA-binding protein HCH_00375 12 None None None 83648757 Nonpathogen - hypothetical protein HCH_06119 2 None None None 83649461 Nonpathogen - hypothetical protein HCH_06851 3 None None None 83649394 Common - uncharacterized phage Mu protein gp47-like protein HCH_06780 14 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 83649556 Nonpathogen - hypothetical protein HCH_06948 1 None None None 83647874 Common - aspartate kinase HCH_05208 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 83642951 Common motB Flagellar motor protein HCH_00039 142 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83646571 Common - hypothetical protein HCH_03853 5 None None None 83646595 Nonpathogen - hypothetical protein HCH_03878 2 None None None 83646974 Common - thiamine pyrophosphate-requiring enzyme HCH_04277 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83644942 Common ppsA phosphoenolpyruvate synthase HCH_02123 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 83644937 Nonpathogen - hypothetical protein HCH_02119 1 None None None 83645226 Common leuC isopropylmalate isomerase large subunit HCH_02428 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 83646636 Common gor glutathione-disulfide reductase HCH_03925 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83644012 Common - Transcriptional regulator HCH_01145 183 COG0583 LysR, Transcriptional regulator Transcription 83644257 Common - predicted phosphatase HCH_01404 112 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 83646432 Common - Methylase of chemotaxis methyl-accepting protein HCH_03705 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83646964 Common - Signal transduction histidine kinase HCH_04267 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647945 Common coaE dephospho-CoA kinase HCH_05281 197 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 83648473 Nonpathogen - hypothetical protein HCH_05833 1 None None None 83648555 Common ilvC ketol-acid reductoisomerase HCH_05914 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 83646148 Common - 3-hydroxyacyl-CoA dehydrogenase HCH_03409 163 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 83647196 Common - hypothetical protein HCH_04504 38 COG3287 COG3287, Uncharacterized conserved protein Function unknown 83643733 Common betB betaine aldehyde dehydrogenase HCH_00850 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83647855 Common - protein containing STAS (Sulphate Transporter and AntiSigma factor antagonist) domain HCH_05187 12 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 83644137 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_01279 40 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83647449 Common - Chemotaxis signal transduction protein HCH_04764 163 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83647451 Common - hypothetical protein HCH_04766 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 83648008 Common - Nucleoid-associated protein HCH_05346 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 83646506 Common - Rhs family protein HCH_03784 74 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83643847 Common - Signal transduction histidine kinase HCH_00968 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644458 Common thiP thiamin transporter membrane protein HCH_01611 52 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 83647773 Nonpathogen - protein containing tetratricopeptide repeats HCH_05102 1 None None None 83644921 Common - IS116/IS110/IS902 family transposase HCH_02102 68 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644679 Common - AraC-type DNA-binding domain-containing protein HCH_01851 139 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83647372 Common - glycosyltransferase HCH_04683 206 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 83647942 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_05278 220 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 83648159 Nonpathogen - hypothetical protein HCH_05507 1 None None None 83647076 Common - predicted periplasmic or secreted lipoprotein HCH_04381 58 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 83646025 Nonpathogen - hypothetical protein HCH_03278 1 None None None 83649276 Common - Site-specific DNA methylase HCH_06653 72 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 83649418 Nonpathogen - hypothetical protein HCH_06804 4 None None None 83649635 Nonpathogen - hypothetical protein HCH_07029 1 None None None 83644817 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_01993 68 COG0456 RimI, Acetyltransferases General function prediction only 83644227 Nonpathogen - hypothetical protein HCH_01374 1 None None None 83644623 Common nadB L-aspartate oxidase HCH_01789 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 83646559 Common - hypothetical protein HCH_03841 3 None None None 83644611 Common dsbC Protein-disulfide isomerase HCH_01777 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 83644515 Nonpathogen - hypothetical protein HCH_01672 1 None None None 83645583 Common - hypothetical protein HCH_02815 29 None None None 83642984 Common hypD hydrogenase expression/formation protein HypD HCH_00073 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83643605 Nonpathogen - hypothetical protein HCH_00717 1 None None None 83647032 Nonpathogen - hypothetical protein HCH_04336 1 None None None 83649582 Common tonB Periplasmic protein TonB, links inner and outer membranes HCH_06977 55 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83643911 Common dtd D-tyrosyl-tRNA deacylase HCH_01039 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 83648037 Common - ATP phosphoribosyltransferase involved in histidine biosynthesis HCH_05378 225 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 83645142 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_02329 71 COG2153 ElaA, Predicted acyltransferase General function prediction only 83648423 Nonpathogen - hypothetical protein HCH_05781 1 COG5373 COG5373, Predicted membrane protein Function unknown 83648837 Common rplF 50S ribosomal protein L6 HCH_06201 241 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 83644092 Common - predicted RNA-binding protein containing KH domain, possibly ribosomal protein HCH_01230 95 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 83645431 Common - Type II secretory pathway, component ExeA (predicted ATPase) HCH_02652 69 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 83643242 Common cfa Cyclopropane fatty acid synthase and related methyltransferase HCH_00340 109 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83644173 Common - hypothetical protein HCH_01315 6 None None None 83649589 Common nagB glucosamine-6-phosphate isomerase HCH_06984 84 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 83647038 Nonpathogen - hypothetical protein HCH_04342 20 COG1628 COG1628, Uncharacterized conserved protein Function unknown 83649096 Common cobD cobalamin biosynthesis protein HCH_06462 151 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 83643896 Common coaBC phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase HCH_01021 233 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 83643672 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00786 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83646979 Nonpathogen - 3-oxoacyl-(acyl-carrier-protein) synthase HCH_04282 5 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83646695 Nonpathogen - hypothetical protein HCH_03987 1 None None None 83643537 Common hemH ferrochelatase HCH_00646 161 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 83645587 Common - uncharacterized protein predicted to be involved in DNA repair HCH_02819 46 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83645706 Common - hypothetical protein HCH_02944 15 None None None 83648736 Common slmA nucleoid occlusion protein HCH_06098 60 COG1309 AcrR, Transcriptional regulator Transcription 83646193 Common - ABC-type Fe3+-siderophore transport system, permease component HCH_03456 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83648900 Common folK1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HCH_06263 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 83648968 Common - predicted ATPase (AAA+ superfamily) HCH_06332 23 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 83645947 Common - Transposase and inactivated derivatives HCH_03196 95 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644847 Common - hypothetical protein HCH_02023 9 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 83647829 Common - hypothetical protein HCH_05160 11 None None None 83643077 Common - sigma54-dependent transcription regulator RtcR HCH_00168 164 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 83647650 Common - hypothetical protein HCH_04970 141 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 83647572 Nonpathogen - hypothetical protein HCH_04891 1 None None None 83649548 Common - Cation/multidrug efflux pump HCH_06941 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83643386 Common - Esterase/lipase HCH_00489 124 COG0657 Aes, Esterase/lipase Lipid metabolism 83646384 Common - hypothetical protein HCH_03654 12 COG5453 COG5453, Uncharacterized conserved protein Function unknown 83646441 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_03715 191 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83644954 Common rne Ribonucleases G and E HCH_02135 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 83649436 Nonpathogen - hypothetical protein HCH_06823 1 None None None 83643072 Nonpathogen - hypothetical protein HCH_00163 1 None None None 83646017 Common - predicted ATPase HCH_03269 6 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 83645303 Common - Universal stress protein UspA and related nucleotide-binding protein HCH_02511 71 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83646251 Common - Cu/Zn superoxide dismutase HCH_03516 20 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 83643567 Nonpathogen - hypothetical protein HCH_00677 1 None None None 83647671 Common pyrC dihydroorotase HCH_04992 101 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 83646736 Nonpathogen - hypothetical protein HCH_04031 1 None None None 83647126 Common - Transposase and inactivated derivatives HCH_04432 16 None None None 83643000 Common - uncharacterized protein containing a von Willebrand factor type A (vWA) domain HCH_00089 53 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 83646182 Common - Non-ribosomal peptide synthetase modules and related protein HCH_03445 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648205 Nonpathogen - hypothetical protein HCH_05555 1 None None None 83644278 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_01427 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83644220 Common cca tRNA nucleotidyltransferase HCH_01366 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 83644762 Common - uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis HCH_01938 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 83646668 Nonpathogen - hypothetical protein HCH_03959 1 None None None 83646724 Common - predicted membrane protein HCH_04018 40 COG3336 COG3336, Predicted membrane protein Function unknown 83645667 Common - hypothetical protein HCH_02903 8 None None None 83646097 Common - hypothetical protein HCH_03353 8 None None None 83646189 Common - Acyl-CoA dehydrogenase HCH_03452 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83649489 Nonpathogen - hypothetical protein HCH_06882 1 None None None 83645979 Nonpathogen - protein containing hemolysin-type calcium-binding repeats HCH_03229 2 None None None 83646041 Common - ABC-type sugar transport system, periplasmic component HCH_03296 91 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83647282 Common - Diadenosine tetraphosphatase and related serine/threonine protein phosphatase HCH_04591 58 None None None 83647259 Nonpathogen - hypothetical protein HCH_04567 1 None None None 83649511 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_06903 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83644499 Common asnB1 asparagine synthase (glutamine-hydrolyzing) HCH_01655 157 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83648936 Common - Signal transduction histidine kinase HCH_06299 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83647290 Nonpathogen - hypothetical protein HCH_04599 1 None None None 83644133 Common - hypothetical protein HCH_01275 15 None None None 83647049 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_04353 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644065 Nonpathogen - hypothetical protein HCH_01202 1 None None None 83647523 Common - hypothetical protein HCH_04839 49 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 83643996 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_01128 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83643819 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_00941 17 COG3889 COG3889, Predicted solute binding protein General function prediction only 83647508 Common - Serine acetyltransferase HCH_04824 115 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83644777 Common - FOG: FHA domain HCH_01954 25 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 83645423 Nonpathogen - hypothetical protein HCH_02644 1 None None None 83645469 Common - Membrane-associated lipoprotein involved in thiamine biosynthesis HCH_02692 140 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 83646786 Common flgH1 Flagellar basal body L-ring protein HCH_04083 100 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 83648627 Common - hypothetical protein HCH_05987 6 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 83647429 Common sucC succinyl-CoA synthetase subunit beta HCH_04741 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 83643058 Nonpathogen - hypothetical protein HCH_00149 1 None None None 83645278 Common - Transcriptional regulator HCH_02485 152 COG1522 Lrp, Transcriptional regulators Transcription 83648955 Common - Alcohol dehydrogenase, class IV HCH_06318 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 83647107 Nonpathogen - hypothetical protein HCH_04413 1 None None None 83649380 Common - probable phage capsid scaffolding protein HCH_06765 22 None None None 83646242 Nonpathogen - hypothetical protein HCH_03506 7 None None None 83646861 Common lhr Lhr-like helicase HCH_04162 206 COG1201 Lhr, Lhr-like helicases General function prediction only 83647822 Nonpathogen - hypothetical protein HCH_05152 1 None None None 83645271 Common - Cytochrome c peroxidase HCH_02475 95 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 83648984 Common thrB homoserine kinase HCH_06348 63 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 83643062 Common - Peroxiredoxin HCH_00153 106 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83648518 Common ftsA cell division protein FtsA HCH_05879 196 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 83643990 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_01122 167 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83648041 Common - GTPase HCH_05382 221 COG2262 HflX, GTPases General function prediction only 83644590 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase HCH_01754 133 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83645842 Common - ABC-type Fe3+ transport system, permease component HCH_03086 221 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 83646938 Common - Signal transduction histidine kinase HCH_04241 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 83648862 Common rplA ribosomal protein L1 HCH_06227 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 83645694 Nonpathogen - hypothetical protein HCH_02932 1 None None None 83645857 Common - ADP-ribose pyrophosphatase HCH_10012 125 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83646031 Common - probable regulatory protein, luxR family HCH_03285 63 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 83647810 Common - Transcriptional regulator HCH_05140 40 COG1309 AcrR, Transcriptional regulator Transcription 83648848 Common rpsS ribosomal protein S19 HCH_06213 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 83649242 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_06618 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83644896 Common - Rhs family protein HCH_02075 72 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83643457 Common - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) HCH_00563 113 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 83647436 Common sdhC succinate dehydrogenase (C subunit) HCH_04749 91 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 83645615 Common - predicted acyl-CoA transferase/carnitine dehydratase HCH_02848 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 83645458 Common - Small-conductance mechanosensitive channel HCH_02680 180 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83646258 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs HCH_03523 220 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83643684 Common mnhG Multisubunit Na+/H+ antiporter, MnhG subunit HCH_00799 52 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 83646555 Common - Fatty acid desaturase HCH_03837 28 COG3239 DesA, Fatty acid desaturase Lipid metabolism 83646569 Common - Chemotaxis signal transduction protein HCH_03851 99 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83645850 Nonpathogen - hypothetical protein HCH_03094 1 None None None 83648688 Common - hypothetical protein HCH_06047 15 None None None 83643031 Common - predicted phosphatase HCH_00120 67 COG3211 PhoX, Predicted phosphatase General function prediction only 83643690 Common - Carbonic anhydrase HCH_00805 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 83648090 Common - Transcriptional regulator HCH_05435 157 COG1309 AcrR, Transcriptional regulator Transcription 83648977 Common - predicted Permease HCH_06341 30 COG0730 COG0730, Predicted permeases General function prediction only 83644649 Common - Cytochrome B561 HCH_01820 84 COG3038 CybB, Cytochrome B561 Energy production and conversion 83645245 Common crcB Integral membrane protein possibly involved in chromosome condensation HCH_02448 189 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 83646997 Common - hypothetical protein HCH_04300 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 83648704 Nonpathogen - hypothetical protein HCH_06065 1 None None None 83646284 Nonpathogen - hypothetical protein HCH_03552 1 None None None 83644206 Common - Membrane-bound metallopeptidase HCH_01351 205 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 83647276 Common - uncharacterized protein related to plant photosystem II stability/assembly factor HCH_04585 39 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 83646396 Common - hypothetical protein HCH_03666 8 None None None 83645462 Common gap3 glyceraldehyde-3-phosphate dehydrogenase HCH_02684 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 83643643 Common - hypothetical protein HCH_00756 5 None None None 83644356 Common ectC L-ectoine synthase HCH_01508 35 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 83646527 Common - Type II restriction enzyme, methylase subunit HCH_03806 55 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 83647287 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family HCH_04596 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 83643916 Common glnE Glutamine synthetase adenylyltransferase HCH_01044 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 83645645 Nonpathogen - hypothetical protein HCH_02879 1 None None None 83644121 Common - ABC-type antimicrobial peptide transport system, permease component HCH_01262 173 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 83649638 Nonpathogen - hypothetical protein HCH_07033 1 None None None 83645973 Common - protein containing hemopexin repeats HCH_03222 19 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 83643065 Nonpathogen - hypothetical protein HCH_00156 1 None None None 83643459 Common cysQ 3'(2'),5'-bisphosphate nucleotidase HCH_00565 164 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 83643570 Nonpathogen - hypothetical protein HCH_00680 1 None None None 83645953 Nonpathogen - hypothetical protein HCH_03202 1 None None None 83645685 Nonpathogen - hypothetical protein HCH_02922 1 None None None 83649324 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component HCH_06706 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 83644323 Nonpathogen - hypothetical protein HCH_01475 4 COG5607 COG5607, Uncharacterized conserved protein Function unknown 83646369 Nonpathogen - probable deoxygenase HCH_03639 2 None None None 83649642 Common - hypothetical protein HCH_07037 5 None None None 83648009 Common - hypothetical protein HCH_05347 15 COG4517 COG4517, Uncharacterized protein conserved in bacteria Function unknown 83646714 Common - Parvulin-like peptidyl-prolyl isomerase HCH_04007 69 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 83648274 Common - hypothetical protein HCH_05626 13 None None None 83645289 Common - predicted nucleoside-diphosphate sugar epimerase HCH_02496 88 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 83646928 Nonpathogen - hypothetical protein HCH_04231 2 None None None 83647685 Common - Signal transduction histidine kinase HCH_05010 221 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 83647171 Common flgG flagellar basal body rod protein FlgG HCH_04477 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 83646073 Common - hypothetical protein HCH_03328 6 None None None 83648073 Common - uncharacterized protein containing a von Willebrand factor type A (vWA) domain HCH_05414 10 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 83648802 Common - Adenylylsulfate kinase and related kinase HCH_06167 146 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 83649574 Common - ABC-type sugar transport system, permease components HCH_06969 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83644838 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02014 40 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645571 Common - Membrane protease subunit stomatin/prohibitin-like protein HCH_02803 29 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83644853 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02029 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648102 Nonpathogen - hypothetical protein HCH_05447 1 None None None 83644317 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family HCH_01469 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 83645400 Common - uncharacterized protein containing a von Willebrand factor type A (vWA) domain HCH_02620 19 COG5593 COG5593, Nucleic-acid-binding protein possibly involved in ribosomal biogenesis Translation, ribosomal structure and biogenesis 83643398 Common - Transcriptional regulator HCH_00501 138 COG1846 MarR, Transcriptional regulators Transcription 83648314 Common - Periplasmic serine protease (ClpP class) HCH_05669 170 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83648372 Nonpathogen - hypothetical protein HCH_05729 1 None None None 83645038 Nonpathogen - hypothetical protein HCH_02221 1 None None None 83644642 Common - predicted signal transduction protein HCH_01812 74 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83645282 Common - BamHI-like site-specific methyltransferase HCH_02488 114 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 83645849 Nonpathogen - hypothetical protein HCH_03093 1 None None None 83645894 Common - hypothetical protein HCH_03141 11 None None None 83644806 Nonpathogen - hypothetical protein HCH_01983 1 None None None 83648673 Common - Polyketide synthase modules and related protein HCH_06033 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83647974 Common - ABC-type transport system involved in resistance to organic solvents, auxiliary component HCH_05311 24 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 83645473 Common - Glycerophosphoryl diester phosphodiesterase HCH_02696 160 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 83644964 Common fabG 3-oxoacyl-(acyl-carrier-protein) reductase HCH_02144 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83647225 Common - Acylphosphatase HCH_04535 120 COG1254 AcyP, Acylphosphatases Energy production and conversion 83644708 Nonpathogen - hypothetical protein HCH_01881 1 None None None 83644648 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_01819 125 None None None 83645747 Common - 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benz oquinol methylase HCH_02988 153 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83645441 Common pabB para-aminobenzoate synthase, component I HCH_02662 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 83648335 Common - hypothetical protein HCH_05689 10 None None None 83649425 Common - predicted membrane protein HCH_06812 16 COG4763 COG4763, Predicted membrane protein Function unknown 83648752 Common - RTX toxins and related Ca2+-binding protein HCH_06114 47 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 83643748 Common - uncharacterized membrane-anchored protein HCH_00866 16 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 83647957 Common - hypothetical protein HCH_05294 24 COG3339 COG3339, Uncharacterized conserved protein Function unknown 161897903 Common argA N-acetylglutamate synthase HCH_01030 181 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 83643514 Common - predicted transcriptional regulator HCH_00622 37 COG3311 AlpA, Predicted transcriptional regulator Transcription 83647236 Nonpathogen - hypothetical protein HCH_04546 1 None None None 83644197 Common mutY A/G-specific adenine glycosylase HCH_01340 230 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 83644992 Common - predicted ATPase of the PP-loop superfamily implicated in cell cycle control HCH_02174 157 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 83647298 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_04607 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83648570 Common pilW Tfp pilus assembly protein PilW HCH_05929 11 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 83645359 Nonpathogen - hypothetical protein HCH_02569 2 None None None 83649161 Nonpathogen - hypothetical protein HCH_06532 1 None None None 83649660 Common - hypothetical protein HCH_07058 23 COG5351 COG5351, Uncharacterized protein conserved in bacteria Function unknown 83644406 Nonpathogen - hypothetical protein HCH_01559 1 None None None 83644049 Nonpathogen - hypothetical protein HCH_01183 1 None None None 83643300 Nonpathogen - hypothetical protein HCH_00399 1 None None None 83646600 Common - hypothetical protein HCH_03884 4 None None None 83644548 Common spoU rRNA methylases HCH_01710 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 83648390 Common - Acetyl-CoA carboxylase, carboxyltransferase component (subunit alpha and beta) HCH_05748 146 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83648873 Common - protein containing OB-fold nucleic acid binding domain HCH_06237 39 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 83644110 Common - ABC-type branched-chain amino acid transport system, ATPase component HCH_01250 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83643942 Common ubiH 2-octaprenyl-6-methoxyphenyl hydroxylase HCH_01071 116 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 83649113 Nonpathogen - hypothetical protein HCH_06482 1 None None None 83647926 Common - hypothetical protein HCH_05262 6 None None None 83645913 Nonpathogen - hypothetical protein HCH_03160 1 None None None 83646453 Nonpathogen - hypothetical protein HCH_03728 1 None None None 83643623 Nonpathogen - hypothetical protein HCH_00735 1 None None None 83648345 Common - hypothetical protein HCH_05699 16 None None None 83647488 Common acsA1 acetate--CoA ligase HCH_04804 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 83647096 Common - hypothetical protein HCH_04401 2 None None None 83649003 Common - predicted ATPase with chaperone activity HCH_06368 186 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 83648409 Common - predicted dehydrogenase and related protein HCH_05768 184 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 83644653 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase HCH_01824 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 83648592 Common - Phosphatidylglycerophosphatase A and related protein HCH_05951 104 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 83645120 Nonpathogen - hypothetical protein HCH_02307 3 None None None 83643616 Common - predicted metal-dependent Hydrolase related to alanyl-tRNA synthetase HxxxH domain HCH_00728 209 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 83645154 Nonpathogen - hypothetical protein HCH_02341 1 None None None 83647790 Common - type III secretion system protein HCH_05119 30 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83645162 Common - hypothetical protein HCH_02349 5 None None None 83646704 Nonpathogen - hypothetical protein HCH_03997 1 None None None 83645139 Common - hypothetical protein HCH_02326 16 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 83643480 Nonpathogen - hypothetical protein HCH_00587 1 None None None 83648331 Common - hypothetical protein HCH_05685 59 COG3378 COG3378, Predicted ATPase General function prediction only 83648402 Common - hypothetical protein HCH_05761 4 None None None 83649158 Common - Permease of the major facilitator superfamily HCH_06529 7 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83646562 Nonpathogen - hypothetical protein HCH_03844 1 None None None 83646002 Common - Rhs family protein HCH_03253 48 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83642919 Common - Multiple antibiotic transporter HCH_00006 153 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 83643697 Common - hypothetical protein HCH_00813 15 None None None 83645651 Common - Negative regulator of beta-lactamase expression HCH_02886 20 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 83647858 Common fliI flagellum-specific ATP synthase HCH_05190 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 83643195 Common algR alginate biosynthesis regulatory protein AlgR-like protein HCH_00292 224 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 83646090 Nonpathogen - hypothetical protein HCH_03346 1 None None None 83646719 Common - Signal transduction histidine kinase, nitrate/nitrite-specific HCH_04013 162 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 83649534 Nonpathogen - hypothetical protein HCH_06927 1 None None None 83644026 Common iolD Acetolactate synthase HCH_01159 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 83645788 Nonpathogen - hypothetical protein HCH_03032 1 None None None 83647359 Nonpathogen - hypothetical protein HCH_04670 2 None None None 83647799 Nonpathogen - hypothetical protein HCH_05129 1 None None None 83648221 Common - Cold shock protein HCH_05571 178 COG1278 CspC, Cold shock proteins Transcription 83644413 Common - probable RNA-binding protein containing TROVE domain HCH_01566 16 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 83648573 Common - FKBP-type peptidyl-prolyl cis-trans isomerases 2 HCH_05931 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 83647406 Nonpathogen - hypothetical protein HCH_04718 1 None None None 83644420 Common - enoyl-CoA hydratase HCH_01573 140 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83647741 Common - hypothetical protein HCH_05068 51 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 83645114 Common - aminotransferase AlaT HCH_02301 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83647352 Common - putative sulfate transporter YchM HCH_04663 155 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 83647468 Common - uncharacterized protein containing a von Willebrand factor type A (vWA) domain HCH_04784 71 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 83643955 Nonpathogen - hypothetical protein HCH_01085 2 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83643253 Nonpathogen - hypothetical protein HCH_00351 8 None None None 83648382 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_05739 220 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645800 Common pntB pyridine nucleotide transhydrogenase HCH_03044 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 161897892 Common - nicotinamide-nucleotide adenylyltransferase HCH_06993 109 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83646809 Common - hypothetical protein HCH_04109 24 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 83644795 Nonpathogen - hypothetical protein HCH_01972 1 None None None 83648809 Common - Membrane-fusion protein HCH_06174 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83644347 Common - Leucine-rich repeat (LRR) protein HCH_01499 19 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 83646203 Common - probable phage resistance protein HCH_03466 11 None None None 83649679 Common atpB2 F0F1 ATP synthase subunit A HCH_07078 201 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 83645350 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_02560 189 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83647558 Common - Phospholipid-binding protein HCH_04877 126 COG1881 COG1881, Phospholipid-binding protein General function prediction only 83646154 Nonpathogen - hypothetical protein HCH_03416 1 None None None 83646909 Nonpathogen - hypothetical protein HCH_04212 6 None None None 83647100 Common - ABC-type multidrug transport system, ATPase and permease components HCH_04405 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83645076 Common - Mannose-6-phosphate isomerase HCH_02260 16 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 83643136 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB HCH_00231 238 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 83643296 Common - Flagellar biosynthesis/type III secretory pathway protein HCH_00395 22 None None None 83648094 Common - predicted DNA alkylation repair enzyme HCH_05439 31 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 83643109 Common - ABC-type sugar transport system, permease components HCH_00203 171 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83648585 Common - predicted membrane-associated, metal-dependent hydrolase HCH_05944 27 None None None 83649480 Nonpathogen - hypothetical protein HCH_06872 1 None None None 83646270 Nonpathogen - hypothetical protein HCH_03537 1 None None None 83647815 Nonpathogen - hypothetical protein HCH_05145 1 None None None 83645031 Common - putative lipid carrier protein HCH_02213 31 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 83648419 Common - hypothetical protein HCH_05778 39 COG2898 COG2898, Uncharacterized conserved protein Function unknown 83645632 Nonpathogen - hypothetical protein HCH_02865 1 None None None 83645068 Nonpathogen - hypothetical protein HCH_02252 1 None None None 83644141 Common - Transcriptional regulator HCH_01283 172 COG0583 LysR, Transcriptional regulator Transcription 83644216 Common - glycine betaine transporter membrane protein HCH_01362 215 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 83643794 Nonpathogen - hypothetical protein HCH_00914 1 None None None 83646807 Nonpathogen - hypothetical protein HCH_04106 1 None None None 83647788 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_05117 47 COG3153 COG3153, Predicted acetyltransferase General function prediction only 83648417 Common - TRAP-type C4-dicarboxylate transport system, large permease component HCH_05776 130 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 83646903 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_04206 11 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83643158 Nonpathogen - hypothetical protein HCH_00255 1 None None None 83646640 Common gspL Type II secretory pathway, component PulL HCH_03929 17 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 83647087 Common - hypothetical protein HCH_04392 115 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83645482 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase HCH_02706 144 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 83645896 Nonpathogen - hypothetical protein HCH_03143 1 None None None 83648643 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_06003 218 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83649604 Common - Superfamily II DNA/RNA helicase, SNF2 family HCH_06999 149 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 83648773 Nonpathogen - hypothetical protein HCH_06135 1 None None None 83644050 Common - Zn-dependent Hydrolase, including glyoxylases HCH_01185 26 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83648264 Nonpathogen - hypothetical protein HCH_05616 1 None None None 83649687 Common - Membrane transporters of cations and cationic drugs HCH_07085 122 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 83645105 Common - Phosphoglycerate dehydrogenase and related dehydrogenase HCH_02292 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 83649211 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_06584 91 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83644884 Common htpG2 heat shock protein 90 HCH_02063 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 83643645 Common - predicted alpha/beta hydrolase HCH_00758 48 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 83647059 Common ccmG cytochrome c-type biogenesis protein CcmG HCH_04363 151 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83645838 Common - Glycine/D-amino acid oxidases (deaminating) HCH_03082 48 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83649568 Common - Transcriptional regulator of sugar metabolism HCH_06963 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 83648431 Common - putative heme iron utilization protein HCH_05790 20 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 83646332 Common - Polyketide synthase modules and related protein HCH_03602 3 None None None 83649234 Common - hypothetical protein HCH_06610 30 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 83643727 Nonpathogen - hypothetical protein HCH_00845 1 None None None 83645315 Common - predicted signal transduction protein HCH_02523 43 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83648289 Nonpathogen - hypothetical protein HCH_05641 3 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 83644829 Common - AraC-type DNA-binding domain-containing protein HCH_02005 152 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83648410 Nonpathogen - hypothetical protein HCH_05769 1 None None None 83645725 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02964 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83649536 Common - ribonucleotide-diphosphate reductase subunit alpha HCH_06929 227 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 83647389 Common - Cytochrome c peroxidase HCH_04701 33 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 83643326 Common - uncharacterized Fe-S protein HCH_00426 17 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 83645387 Common - Membrane-bound lytic murein transglycosylase B HCH_02605 109 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 83645471 Nonpathogen - hypothetical protein HCH_02694 1 None None None 83643898 Common - Phosphomannomutase HCH_01025 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 83645236 Common folC Folylpolyglutamate synthase HCH_02439 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 83644314 Common - Cation/multidrug efflux pump HCH_01466 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83642971 Common - hypothetical protein HCH_00059 6 None None None 83645487 Common - methylcitrate synthase HCH_02711 194 COG0372 GltA, Citrate synthase Energy production and conversion 83643009 Common udk uridine kinase HCH_00098 87 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 83648252 Nonpathogen - hypothetical protein HCH_05603 1 None None None 83645767 Nonpathogen - hypothetical protein HCH_03009 1 None None None 83643858 Common - hypothetical protein HCH_00981 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 83647494 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04810 12 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646314 Common - hypothetical protein HCH_03582 9 None None None 83649245 Common - Transcriptional regulator HCH_06621 165 COG0583 LysR, Transcriptional regulator Transcription 83643225 Common - hypothetical protein HCH_00323 91 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 83645503 Common - Glycosyltransferase HCH_02728 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83643265 Common - Restriction endonuclease HCH_00363 102 COG1403 McrA, Restriction endonuclease Defense mechanisms 83648490 Common - uncharacterized membrane-associated protein HCH_05850 149 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 83646727 Common - DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) HCH_04021 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83647408 Common - Flagellar basal body P-ring biosynthesis protein HCH_04720 49 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 83643863 Common - Phage shock protein A (IM30), suppresses sigma54-dependent transcription HCH_00987 16 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 83647729 Common - predicted transcriptional regulator HCH_05056 31 COG1476 COG1476, Predicted transcriptional regulators Transcription 83648101 Common - uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism HCH_05446 76 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 83645506 Common wcaK polysaccharide pyruvyl transferase family protein HCH_02731 21 COG2327 WcaK, Uncharacterized conserved protein Function unknown 83646620 Nonpathogen - hypothetical protein HCH_03908 1 None None None 83648075 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component HCH_05416 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 83644390 Nonpathogen - hypothetical protein HCH_01542 6 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 83647986 Common - hypothetical protein HCH_05324 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 83646038 Nonpathogen - hypothetical protein HCH_03293 1 None None None 83647144 Common ackA acetate kinase HCH_04450 162 COG0282 ackA, Acetate kinase Energy production and conversion 83647781 Common yscQ putative type III secretion protein YscQ HCH_05110 17 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83648655 Nonpathogen - hypothetical protein HCH_06015 2 None None None 83644711 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs HCH_01884 213 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83643611 Common - short-chain alcohol dehydrogenase-like protein HCH_00723 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83647622 Common guaB inosine-5'-monophosphate dehydrogenase HCH_04943 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 83645889 Common - predicted metal-dependent hydrolase HCH_03135 11 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 83645660 Common - Periplasmic serine protease (ClpP class) HCH_02896 152 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83649543 Common - Sortase and related acyltransferase HCH_06936 128 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 83648247 Common - hypothetical protein HCH_05598 14 None None None 83643618 Nonpathogen - protein of unknown function (DUF1555) HCH_00730 1 None None None 83648182 Common - Transcriptional regulator HCH_05530 174 COG0583 LysR, Transcriptional regulator Transcription 83644399 Common - uncharacterized protein containing a von Willebrand factor type A (vWA) domain HCH_01552 41 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 83646770 Common fliP flagellar biosynthesis protein FliP HCH_04067 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 83647233 Nonpathogen - hypothetical protein HCH_04543 1 None None None 83647896 Nonpathogen - protein containing fibronectin type III domain HCH_05231 2 None None None 83645605 Common - hypothetical protein HCH_02837 3 None None None 83649347 Common - N-acyl-D-glucosamine 2-epimerase HCH_06731 10 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 83645044 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase HCH_02227 212 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 83643668 Common - predicted Zn-dependent Hydrolase of the beta-lactamase fold HCH_00782 118 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 83644349 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_01501 43 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83643825 Common - Signal transduction histidine kinase HCH_00947 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 83649278 Common - Membrane protein TerC, possibly involved in tellurium resistance HCH_06655 99 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 83644811 Common - putative threonine efflux protein HCH_10007 8 None None None 83647245 Common - phage portal protein, HK97 family HCH_04555 68 COG4695 COG4695, Phage-related protein Function unknown 83647630 Common - predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component HCH_04951 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 83644822 Nonpathogen - hypothetical protein HCH_01998 1 None None None 83644695 Common - hypothetical protein HCH_10037 6 None None None 83649176 Nonpathogen - hypothetical protein HCH_06547 6 None None None 83647414 Common - hypothetical protein HCH_04726 114 COG4121 COG4121, Uncharacterized conserved protein Function unknown 83646589 Nonpathogen - hypothetical protein HCH_03872 2 None None None 83643407 Common - Arsenite efflux pump ACR3 and related Permease HCH_00510 126 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 83644248 Common - ABC-type Fe3+-citrate transport system, periplasmic component HCH_01395 87 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 83649522 Common - Secreted trypsin-like serine protease HCH_06915 25 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 83645405 Nonpathogen - hypothetical protein HCH_02625 6 None None None 83649326 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components HCH_06708 77 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 83646292 Nonpathogen - hypothetical protein HCH_03560 1 None None None 83648941 Common - hypothetical protein HCH_06304 101 COG1262 COG1262, Uncharacterized conserved protein Function unknown 83646983 Nonpathogen - hypothetical protein HCH_04286 2 None None None 83647257 Common - group II intron-encoding maturase HCH_04565 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83644775 Common - Serine/threonine protein kinase HCH_01952 154 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83649291 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06670 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643576 Common - uncharacterized membrane protein HCH_00686 89 COG1285 SapB, Uncharacterized membrane protein Function unknown 83648818 Nonpathogen - hypothetical protein HCH_06184 1 None None None 83648914 Nonpathogen - hypothetical protein HCH_06277 1 None None None 83645204 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase III HCH_02403 201 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 83648282 Nonpathogen - hypothetical protein HCH_05634 2 None None None 83644415 Nonpathogen - hypothetical protein HCH_01568 1 None None None 83648569 Common - hypothetical protein HCH_05928 4 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 83646751 Common - ATP-dependent Zn protease HCH_04046 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 83645305 Nonpathogen - hypothetical protein HCH_02513 1 None None None 83649629 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_07024 26 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83645079 Common - hypothetical protein HCH_02263 13 None None None 83645197 Common - 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benz oquinol methylase HCH_02395 32 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83646943 Common - hypothetical protein HCH_04246 32 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 83643834 Common phhA phenylalanine 4-monooxygenase HCH_00956 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 83643239 Common - hypothetical protein HCH_00337 63 COG3496 COG3496, Uncharacterized conserved protein Function unknown 83643102 Common - hypothetical protein HCH_00195 5 None None None 83645542 Common - Ferredoxin HCH_02768 47 None None None 83643473 Common - Signal transduction histidine kinase HCH_00580 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643505 Common - RTX toxins and related Ca2+-binding protein HCH_00612 100 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 83644113 Common - Branched-chain amino acid ABC-type transport system, permease components HCH_01254 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83642933 Common - Histidinol phosphatase HCH_00020 130 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 83646731 Common - FOG: CheY-like receiver HCH_04026 207 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83644007 Nonpathogen - hypothetical protein HCH_01140 1 None None None 83648439 Common pfkA 6-phosphofructokinase HCH_05798 129 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 83644328 Common - hypothetical protein HCH_01480 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 83649375 Nonpathogen - hypothetical protein HCH_06760 1 None None None 83645900 Common - Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) HCH_03147 14 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 83649121 Nonpathogen - hypothetical protein HCH_06490 1 None None None 83648611 Common pilP Tfp pilus assembly protein PilP HCH_10024 38 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 83646423 Common - probable dehydrogenase HCH_03696 6 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83647777 Common yopN putative membrane-bound Yop targeting protein YopN HCH_05106 14 None None None 83643661 Common - hypoxanthine-guanine phosphoribosyltransferase HCH_00775 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 83647517 Common - nucleoside-diphosphate-sugar pyrophosphorylase HCH_04833 221 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 83649527 Common - hypothetical protein HCH_06920 27 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83642968 Nonpathogen - hypothetical protein HCH_00056 3 None None None 83648108 Common - Chitinase HCH_05453 46 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 83643880 Common - polyphosphate kinase HCH_01005 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 83647614 Common - HD-GYP domain HCH_04935 92 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 83644595 Common - hypothetical protein HCH_01760 2 None None None 83645340 Common - Integral membrane protein, interacts with FtsH HCH_02549 91 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 83642991 Common - Glycosyltransferase HCH_00080 114 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83646722 Common - 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzyme HCH_04016 152 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 83645669 Common - Methyl-accepting chemotaxis protein HCH_02905 22 None None None 83649303 Common - DNA-binding winged-HTH domains HCH_06683 26 COG3710 CadC, DNA-binding winged-HTH domains Transcription 83649082 Common - predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component HCH_06448 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83643889 Common - predicted GTPase HCH_01014 185 COG0218 COG0218, Predicted GTPase General function prediction only 83649386 Common - probable phage protein HCH_06772 10 None None None 83647362 Nonpathogen - hypothetical protein HCH_04673 1 None None None 83643182 Nonpathogen - hypothetical protein HCH_00279 2 None None None 83645025 Common potC spermidine/putrescine ABC transporter membrane protein HCH_02207 167 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 83642961 Common coxC cytochrome-c oxidase, subnunit III HCH_00049 148 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 83643191 Common hemY uncharacterized enzyme of heme biosynthesis HCH_00288 53 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 83645260 Nonpathogen - hypothetical protein HCH_02463 1 None None None 83646742 Nonpathogen - hypothetical protein HCH_04037 1 None None None 83649474 Nonpathogen - hypothetical protein HCH_06866 2 None None None 83648793 Common - hypothetical protein HCH_06157 14 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 83647314 Common glpD Glycerol-3-phosphate dehydrogenase HCH_04624 150 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83644059 Common - hypothetical protein HCH_01195 10 None None None 83647640 Nonpathogen - hypothetical protein HCH_04961 1 None None None 83645515 Common - predicted xylanase/chitin deacetylase HCH_02739 35 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 83647844 Common fliR flagellar biosynthesis protein FliR HCH_05176 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 83649612 Nonpathogen - hypothetical protein HCH_07007 1 None None None 83647393 Common - Superfamily II DNA and RNA helicase HCH_04705 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83649550 Nonpathogen - hypothetical protein HCH_06943 1 None None None 83643771 Common - ABC-type amino acid transport system, permease component HCH_00889 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83646681 Nonpathogen - hypothetical protein HCH_03972 1 None None None 83644325 Nonpathogen - hypothetical protein HCH_01477 1 COG4285 COG4285, Uncharacterized conserved protein Function unknown 83646104 Common - hypothetical protein HCH_03360 6 None None None 83643812 Nonpathogen - hypothetical protein HCH_00932 3 None None None 83645352 Common - short-chain alcohol dehydrogenase-like protein HCH_02562 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83648126 Common - hypothetical protein HCH_05473 64 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83645876 Common - Xaa-Pro aminopeptidase HCH_03122 211 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 83647204 Nonpathogen - hypothetical protein HCH_04513 1 None None None 83645268 Common - Sugar (pentulose and hexulose) kinase HCH_02472 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 83643392 Common panE1 2-dehydropantoate 2-reductase HCH_00495 92 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 83643711 Common - Zinc metalloprotease (elastase) HCH_00828 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 83643920 Common - Glycosyltransferase involved in cell wall biogenesis HCH_01048 146 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83645555 Common - MoxR-like ATPase HCH_02785 67 COG0714 COG0714, MoxR-like ATPases General function prediction only 83645251 Common modA molybdate ABC transporter, periplasmic molybdate-binding protein HCH_02454 133 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 83644338 Common - NAD-dependent aldehyde dehydrogenase HCH_01490 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83643174 Common - mannosyl-3-phosphoglycerate phosphatase HCH_00271 32 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 83645349 Common - FOG: CheY-like receiver HCH_02559 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83647200 Common - hypothetical protein HCH_04508 4 None None None 83647669 Common argG argininosuccinate synthase HCH_04989 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 83649147 Common - predicted phosphatase HCH_06517 69 COG3211 PhoX, Predicted phosphatase General function prediction only 83647128 Nonpathogen - hypothetical protein HCH_04434 1 None None None 83649182 Common trxB2 thioredoxin-disulfide reductase HCH_06554 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 83649140 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_06509 18 COG3153 COG3153, Predicted acetyltransferase General function prediction only 83643338 Nonpathogen - hypothetical protein HCH_00438 1 None None None 83647191 Common - Long-chain acyl-CoA synthetases (AMP-forming) HCH_04499 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 83646417 Nonpathogen - hypothetical protein HCH_03688 1 None None None 83645964 Common - Permease of the major facilitator superfamily HCH_03213 11 COG1289 COG1289, Predicted membrane protein Function unknown 83648172 Common - Nucleoside-diphosphate-sugar epimerase HCH_05520 209 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83649400 Common - hypothetical protein HCH_06786 11 None None None 83646360 Common - Beta-lactamase class C and other penicillin binding protein HCH_03630 114 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 83646398 Common - predicted membrane protein HCH_03668 77 COG2119 COG2119, Predicted membrane protein Function unknown 83648235 Nonpathogen - hypothetical protein HCH_05587 1 None None None 83647137 Nonpathogen - hypothetical protein HCH_04443 1 None None None 83646044 Common - ABC-type sugar transport system, ATPase components HCH_03299 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83643754 Common - hypothetical protein HCH_00872 2 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 83646190 Common - Acyl carrier protein HCH_03453 6 None None None 83646573 Common - hypothetical protein HCH_03856 9 None None None 83644573 Common - hypothetical protein HCH_01738 38 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 83645324 Common - putative sterol carrier protein HCH_02532 17 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 83648356 Common - Superfamily I DNA and RNA helicase HCH_05710 156 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 83643542 Common - predicted Rossmann fold nucleotide-binding protein HCH_00651 48 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 83645258 Nonpathogen - hypothetical protein HCH_02461 1 None None None 83645882 Nonpathogen - hypothetical protein HCH_03128 2 None None None 83645989 Common - hypothetical protein HCH_03239 2 None None None 83643019 Common nuoF NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit HCH_00108 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 83648665 Common - Phosphoenolpyruvate synthase/pyruvate phosphate dikinase HCH_06026 147 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 83643010 Nonpathogen - hypothetical protein HCH_00099 1 None None None 83645653 Nonpathogen - hypothetical protein HCH_02888 1 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 83643877 Nonpathogen - hypothetical protein HCH_01002 1 None None None 83645950 Common - Glutathione S-transferase HCH_03199 86 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83648481 Common mltB lytic murein transglycosylase B HCH_05841 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 83646639 Common gspM Type II secretory pathway, component PulM HCH_03928 18 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 83649204 Nonpathogen - hypothetical protein HCH_06577 1 None None None 83646293 Nonpathogen - hypothetical protein HCH_03561 7 None None None 83646913 Common - hypothetical protein HCH_04216 4 None None None 83644295 Common - ATP-dependent transcriptional regulator HCH_01444 113 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 83644357 Common gabT diaminobutyrate--2-oxoglutarate aminotransferase HCH_01509 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 83646012 Common - type III secretion system protein HCH_03263 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 83646655 Common - Enoyl-CoA hydratase/carnithine racemase HCH_03945 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83644985 Common - hypothetical protein HCH_02166 13 None None None 83645918 Nonpathogen - hypothetical protein HCH_03165 1 None None None 83646824 Common - NAD-dependent DNA ligase (contains BRCT domain type II) HCH_04124 12 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 83643986 Common - Permease of the major facilitator superfamily HCH_01118 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83648348 Common - hypothetical protein HCH_05703 10 None None None 83643592 Common - ABC-type oligopeptide transport system, periplasmic component HCH_00703 213 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 83645863 Common - FOG: PAS/PAC domain HCH_03107 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648444 Common - inner membrane protein YjeH HCH_05803 133 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 83645292 Common - dehydrogenase HCH_02500 41 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83643630 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_00741 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83644531 Common - probable glycosyl transferase HCH_01693 10 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 83649269 Common - hypothetical protein HCH_06646 3 COG3272 COG3272, Uncharacterized conserved protein Function unknown 83645928 Common - AraC-type DNA-binding domain-containing protein HCH_03175 30 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83648026 Common bioD dethiobiotin synthase HCH_05366 155 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 83643090 Common - predicted thiol oxidoreductase HCH_00182 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 83647116 Common - Transcriptional regulator HCH_04422 49 COG1522 Lrp, Transcriptional regulators Transcription 83647162 Common yajC preprotein translocase, YajC subunit HCH_04468 165 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 83648211 Common - hypothetical protein HCH_05561 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 83646516 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase components HCH_03795 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83648352 Common - hypothetical protein HCH_10020 4 None None None 83643907 Common - hypothetical protein HCH_01035 16 None None None 83649153 Common - predicted Zn-dependent Hydrolase of the beta-lactamase fold HCH_06524 31 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 83643966 Common allB Dihydroorotase and related cyclic amidoHydrolase HCH_01096 201 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 83645527 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase HCH_02752 47 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83646373 Nonpathogen - hypothetical protein HCH_03643 4 None None None 83643845 Common - FOG: EAL domain HCH_00967 178 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83644506 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_01663 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83645415 Nonpathogen - hypothetical protein HCH_02637 1 None None None 83643415 Common - ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components HCH_00521 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 83645410 Common - Biopolymer transport protein HCH_02631 25 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 83648060 Common - GTPase - translation elongation factors HCH_05401 12 None None None 83649407 Nonpathogen - hypothetical protein HCH_06793 1 None None None 83649120 Nonpathogen - hypothetical protein HCH_06489 1 COG4893 COG4893, Uncharacterized protein conserved in bacteria Function unknown 83643380 Common malT transcriptional regulator MalT HCH_00481 70 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 83645626 Common - putative exonuclease HCH_02859 16 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83649495 Common - uncharacterized flavoprotein HCH_06887 33 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 83644493 Common - Methyl-accepting chemotaxis protein HCH_01649 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83646277 Nonpathogen - hypothetical protein HCH_03545 1 None None None 83647935 Common - Glycosyltransferase involved in cell wall biogenesis HCH_05271 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83645337 Common - uncharacterized conserved protein involved in oxidation of intracellular sulfur HCH_02546 10 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 83645532 Common xth exonuclease III HCH_02757 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 83645797 Common - hypothetical protein HCH_03041 7 None None None 83648883 Common - Chloride channel protein EriC HCH_06246 161 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 83644033 Common - ABC-type sugar transport system, periplasmic component HCH_01166 110 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83649285 Common - protein containing EF hand domain HCH_06662 4 None None None 83646321 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03589 10 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646504 Nonpathogen - hypothetical protein HCH_03782 1 None None None 83643555 Nonpathogen - hypothetical protein HCH_00665 1 None None None 83645433 Common dinG ATP-dependent DNA helicase DinG HCH_02654 138 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 83646110 Common - Methyl-accepting chemotaxis protein HCH_03368 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83646612 Nonpathogen - hypothetical protein HCH_03896 3 None None None 83649316 Common - Glutathione S-transferase HCH_06697 71 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83648403 Nonpathogen - hypothetical protein HCH_05762 1 None None None 83649011 Common - Adenylate cyclase, class 2 (thermophilic) HCH_06375 4 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 83646177 Nonpathogen - probable acetyltransferase HCH_03439 1 COG3393 COG3393, Predicted acetyltransferase General function prediction only 83644253 Common - hypothetical protein HCH_01400 2 None None None 83648726 Common - phospho-2-dehydro-3-deoxyheptonate aldolase HCH_06088 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 83649523 Nonpathogen - hypothetical protein HCH_06916 1 None None None 83644872 Common - soluble pyridine nucleotide transhydrogenase HCH_02051 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83646069 Common - predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase HCH_03324 42 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 83643679 Common - FOG: PAS/PAC domain HCH_00794 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83649448 Common - hypothetical protein HCH_06837 4 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83643492 Nonpathogen - hypothetical protein HCH_00599 3 None None None 83646064 Nonpathogen - hypothetical protein HCH_03319 1 None None None 83649250 Nonpathogen - hypothetical protein HCH_06626 1 None None None 83648850 Common rplW 50S ribosomal protein L23 HCH_06215 212 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 83643149 Common - hypothetical protein HCH_00244 19 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 83646758 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_04053 57 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 83643581 Common cydB cytochrome d ubiquinol oxidase, subunit II HCH_00692 150 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 83642956 Common - predicted nucleic-acid-binding protein containing a Zn-ribbon domain HCH_00044 9 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 83647737 Common - hypothetical protein HCH_05065 2 None None None 83648532 Common - predicted methyltransferase HCH_05893 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 83643140 Common - ABC-type multidrug transport system, permease component HCH_00235 131 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 83645534 Common - HD superfamily phosphohydrolase HCH_02760 71 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 83643524 Nonpathogen - hypothetical protein HCH_00633 1 None None None 83644157 Nonpathogen - hypothetical protein HCH_01300 1 None None None 83647835 Common - chemotaxis-specific methylesterase HCH_05166 212 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83648926 Nonpathogen - hypothetical protein HCH_06287 2 None None None 83646353 Common - Methyl-accepting chemotaxis protein HCH_03623 56 COG5280 COG5280, Phage-related minor tail protein Function unknown 83646832 Common - Membrane-fusion protein HCH_04132 119 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83649094 Common - Nitroreductase HCH_06460 115 COG0778 NfnB, Nitroreductase Energy production and conversion 83646675 Common - predicted nucleotidyltransferase HCH_03966 22 None None None 83647769 Common - FOG: TPR repeat HCH_05098 20 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83643357 Common - Methyl-accepting chemotaxis protein HCH_00457 159 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648112 Common cirA Outer membrane receptor for ferrienterochelin and colicins HCH_05457 124 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 83647071 Common - Small-conductance mechanosensitive channel HCH_04376 203 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83647886 Common - Membrane protein related to metalloendopeptidase HCH_05221 175 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83649221 Common - hypothetical protein HCH_06595 12 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 83644019 Common - hypothetical protein HCH_01152 2 None None None 83648193 Common hscC Molecular chaperone HCH_05542 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83643318 Common - Signal transduction histidine kinase HCH_00418 163 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 83649131 Common - putative threonine efflux protein HCH_06500 79 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83647029 Common - Hydrolase of the alpha/beta superfamily HCH_04333 21 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83649054 Nonpathogen - hypothetical protein HCH_06419 1 None None None 83646386 Common cdtB cytolethal distending toxin B-like protein HCH_03656 7 None None None 83643230 Nonpathogen - hypothetical protein HCH_00328 1 None None None 83646877 Common - Zinc metalloprotease (elastase) HCH_04180 29 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 83645982 Common - hypothetical protein HCH_03232 2 None None None 83648385 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05742 5 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649166 Common - hypothetical protein HCH_06537 3 None None None 83643371 Common - Rhs family protein HCH_00471 37 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83645456 Common - hypothetical protein HCH_02678 42 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 83648628 Common - predicted SAM-dependent methyltransferase HCH_05988 142 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 83647601 Common ruvB Holliday junction DNA helicase B HCH_04922 219 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 83649045 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_06410 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83649264 Nonpathogen - hypothetical protein HCH_06641 1 None None None 83644456 Common - Glycosyltransferase HCH_01609 15 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83646487 Nonpathogen - hypothetical protein HCH_03765 1 None None None 83643588 Common - ABC-type oligopeptide transport system, ATPase component HCH_00699 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 83648618 Common priA primosomal protein N' HCH_05977 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 83646626 Common - Endoglucanase HCH_03914 21 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 83647804 Nonpathogen - hypothetical protein HCH_05134 1 None None None 83645712 Common - hypothetical protein HCH_02950 5 None None None 83647802 Nonpathogen - hypothetical protein HCH_05133 1 None None None 83645297 Nonpathogen - hypothetical protein HCH_02505 1 None None None 83643952 Common ubiE Methylase involved in ubiquinone/menaquinone biosynthesis HCH_01082 208 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83643603 Common - anaerobic nitric oxide reductase transcription regulator HCH_00715 169 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83645056 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_02240 218 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83646215 Nonpathogen - hypothetical protein HCH_03479 1 None None None 83647388 Common - Transcriptional regulator HCH_04700 167 COG0583 LysR, Transcriptional regulator Transcription 83643389 Common - hypothetical protein HCH_00492 7 COG2928 COG2928, Uncharacterized conserved protein Function unknown 83645790 Nonpathogen - hypothetical protein HCH_03034 1 None None None 83644150 Nonpathogen - hypothetical protein HCH_01293 1 None None None 83649038 Common - 3-oxoacyl-(acyl-carrier-protein) synthase HCH_06402 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83643804 Common - Signal transduction histidine kinase regulating C4-dicarboxylate transport system HCH_00924 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83645575 Common - hypothetical protein HCH_02807 23 COG2850 COG2850, Uncharacterized conserved protein Function unknown 83645376 Common - hypothetical protein HCH_02594 9 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 83646888 Common - putative NADP-dependent oxidoreductase HCH_04191 135 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 83647018 Common dinP DNA polymerase IV HCH_04322 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 83642920 Common recF Recombinational DNA repair ATPase (RecF pathway) HCH_00007 161 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 83646893 Common - Metal-dependent Hydrolase of the beta-lactamase superfamily III HCH_04196 14 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 83649653 Common - hypothetical protein HCH_07050 6 None None None 83643742 Nonpathogen - hypothetical protein HCH_00860 2 None None None 83645565 Common - Transcriptional regulator HCH_02797 130 COG1522 Lrp, Transcriptional regulators Transcription 83647563 Nonpathogen - hypothetical protein HCH_04882 1 None None None 83648857 Common rpsL 30S ribosomal protein S12 HCH_06222 245 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 83645777 Common - putative silver efflux pump HCH_03020 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 83647928 Common slyX SlyX family protein HCH_05264 4 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 83644088 Common dapB dihydrodipicolinate reductase HCH_01226 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 83644305 Nonpathogen - hypothetical protein HCH_01455 1 None None None 83649087 Common - hypothetical protein HCH_06453 32 None None None 83646269 Common - predicted Zn-dependent Hydrolase of the beta-lactamase fold HCH_03536 91 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 83644638 Common relA GTP pyrophosphokinase HCH_01807 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 83644053 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family HCH_01188 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 83647660 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase HCH_04980 236 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 83644718 Common rnfC electron transport complex protein RnfC HCH_01892 83 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 83644375 Common - hypothetical protein HCH_01527 16 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 83645172 Nonpathogen - hypothetical protein HCH_02361 1 None None None 83647659 Common cmk cytidylate kinase HCH_04979 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 83649040 Common speE spermidine synthase HCH_06404 117 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 83643499 Nonpathogen - hypothetical protein HCH_00606 1 None None None 83644261 Common - SufE protein probably involved in Fe-S center assembly HCH_01408 94 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 83649453 Common bfr2 bacterioferritin HCH_06842 104 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 83647990 Common - predicted amidohydrolase HCH_05328 205 COG0388 COG0388, Predicted amidohydrolase General function prediction only 83645343 Common - predicted dehydrogenase and related protein HCH_02553 177 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 83648870 Common - Biotin-(acetyl-CoA carboxylase) ligase HCH_06234 229 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 83648301 Common - hypothetical protein HCH_05654 6 None None None 83644186 Common - SAM-dependent methyltransferase HCH_01328 30 None None None 83644098 Common secG preprotein translocase subunit SecG HCH_01236 77 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 83645091 Common ccoN cytochrome c oxidase, cbb3-type, subunit I HCH_02276 157 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 83646301 Nonpathogen - hypothetical protein HCH_03568 1 None None None 83648621 Common hslU ATP-dependent protease ATP-binding subunit HCH_05980 212 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 83647223 Common guaA GMP synthase HCH_04533 216 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 83648040 Common hflK HflK protein HCH_05381 206 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83644665 Common htpX2 heat shock protein HtpX HCH_01836 35 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 83647439 Common topA DNA topoisomerase I HCH_04752 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 83644602 Common - Amino acid transporters HCH_01767 24 None None None 83646464 Nonpathogen - hypothetical protein HCH_03740 1 None None None 83646815 Nonpathogen - hypothetical protein HCH_04115 4 None None None 83646222 Common - Amidases related to nicotinamidase HCH_03486 76 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83643968 Common xdhB Xanthine dehydrogenase, molybdopterin-binding subunit B HCH_01098 108 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 83644742 Common nadC nicotinate-nucleotide pyrophosphorylase HCH_01917 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 83645016 Common purT phosphoribosylglycinamide formyltransferase 2 HCH_02199 199 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 83645569 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02801 30 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647426 Common - hypothetical protein HCH_04738 143 COG1354 COG1354, Uncharacterized conserved protein Function unknown 83649220 Common - hypothetical protein HCH_06594 6 None None None 83646853 Common - hypothetical protein HCH_04154 6 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 83648311 Common - hypothetical protein HCH_05664 4 None None None 83648898 Nonpathogen - hypothetical protein HCH_06260 1 None None None 83646986 Nonpathogen - hypothetical protein HCH_04289 2 None None None 83647955 Nonpathogen - hypothetical protein HCH_05291 2 None None None 83646860 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04161 19 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647431 Common sucB2 dihydrolipoamide acetyltransferase HCH_04744 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 83646564 Common - Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain HCH_03846 222 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83643133 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_00228 31 COG0456 RimI, Acetyltransferases General function prediction only 83648253 Common - hypothetical protein HCH_05605 5 None None None 83647927 Common - Cold shock protein HCH_05263 173 COG1278 CspC, Cold shock proteins Transcription 83647324 Nonpathogen - hypothetical protein HCH_04635 1 None None None 83648697 Common - Acetyltransferase HCH_06057 33 COG0456 RimI, Acetyltransferases General function prediction only 83643156 Common - ABC-type sugar transport system, periplasmic component HCH_00253 61 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83644694 Common eno enolase HCH_01867 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 83646037 Nonpathogen - hypothetical protein HCH_03292 1 None None None 83647271 Common - Translation initiation factor 3 (IF-3) HCH_04579 211 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 83645638 Nonpathogen - hypothetical protein HCH_02872 1 COG1396 HipB, Predicted transcriptional regulators Transcription 83648866 Common tuf2 elongation factor Tu HCH_06231 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 83643278 Nonpathogen - hypothetical protein HCH_00377 1 None None None 83643786 Nonpathogen - hypothetical protein HCH_00905 1 None None None 83643490 Common - phage replication protein O HCH_00597 9 None None None 83644702 Common - predicted membrane protein HCH_01875 48 COG2035 COG2035, Predicted membrane protein Function unknown 83647593 Common nadA quinolinate synthetase HCH_04912 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 83648302 Nonpathogen - hypothetical protein HCH_05655 2 None None None 83645033 Nonpathogen - hypothetical protein HCH_02215 1 None None None 83645695 Nonpathogen - hypothetical protein HCH_02933 1 None None None 83647198 Common - Threonine dehydratase HCH_04506 221 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 83649678 Common atpE2 F0F1 ATP synthase subunit C HCH_07077 73 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 83645066 Nonpathogen - hypothetical protein HCH_02250 1 None None None 83646456 Nonpathogen - hypothetical protein HCH_03732 1 None None None 83643815 Common - hypothetical protein HCH_00935 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 83647156 Common iscR iron-sulfur cluster assembly transcription factor IscR HCH_04462 124 COG1959 COG1959, Predicted transcriptional regulator Transcription 83644024 Common mmsA2 methylmalonate-semialdehyde dehydrogenase HCH_01157 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83645942 Common - Microcystin-dependent protein HCH_03189 35 COG4675 MdpB, Microcystin-dependent protein Function unknown 83649427 Common - putative NADP-dependent oxidoreductase HCH_06814 124 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 83643646 Common - Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family Hydrolase HCH_00759 231 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 83649510 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_06902 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83644353 Nonpathogen - hypothetical protein HCH_01505 1 None None None 83643293 Common - probable phage head completeion protein HCH_00392 19 None None None 83646020 Common - Type III secretory pathway, component EscV HCH_03273 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 83647976 Common - ABC-type transport system involved in resistance to organic solvents, permease component HCH_05313 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 83643779 Common sbcC ATPase involved in DNA repair HCH_00898 205 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 83648564 Common - Signal transduction histidine kinase HCH_05924 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644546 Common - Membrane protein related to metalloendopeptidase HCH_01708 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83647382 Nonpathogen - hypothetical protein HCH_04694 1 None None None 83644247 Common - iron-hydroxamate transporter permease subunit HCH_01394 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83647407 Common - Chemotaxis signal transduction protein HCH_04719 200 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83644613 Common thrA homoserine dehydrogenase HCH_01779 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 83644646 Nonpathogen - hypothetical protein HCH_01817 1 None None None 83645164 Common - ABC-type antimicrobial peptide transport system, ATPase component HCH_02351 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83644235 Nonpathogen - hypothetical protein HCH_01382 1 None None None 83643365 Common - Transcriptional regulator HCH_00465 104 COG2188 PhnF, Transcriptional regulators Transcription 83644067 Nonpathogen - hypothetical protein HCH_01204 1 None None None 83649063 Common - predicted phosphoesterases, related to the Icc protein HCH_06428 21 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 83644969 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase HCH_02149 219 COG1049 AcnB, Aconitase B Energy production and conversion 83645996 Common - hypothetical protein HCH_03246 3 None None None 83648394 Common - short chain dehydrogenase HCH_05753 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 83649108 Common cbiG cobalamin biosynthesis protein CbiG HCH_06476 90 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 83647550 Common - Metal-dependent Hydrolase of the beta-lactamase superfamily III HCH_04868 110 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 83647834 Common motC flagellar motor protein HCH_05165 124 COG1291 MotA, Flagellar motor component Cell motility and secretion 83645174 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02365 39 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643610 Common - hypothetical protein HCH_00722 5 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646702 Nonpathogen - hypothetical protein HCH_03995 2 None None None 83647797 Nonpathogen - hypothetical protein HCH_05127 1 None None None 83647379 Common - polysaccharide pyruvyl transferase family protein HCH_04691 20 COG5039 COG5039, Exopolysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 83647469 Common - hypothetical protein HCH_04785 35 None None None 83643802 Common atpC1 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) HCH_00922 4 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 83647724 Common - predicted signal-transduction protein containing cAMP-binding and CBS domains HCH_05051 138 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 83648575 Common ileS isoleucyl-tRNA synthetase HCH_05933 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83649444 Nonpathogen - hypothetical protein HCH_06833 1 None None None 83647652 Common - Aspartate/tyrosine/aromatic aminotransferase HCH_04972 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83643729 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_00846 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83648587 Common - predicted dioxygenase HCH_05946 66 COG1355 COG1355, Predicted dioxygenase General function prediction only 83648923 Common - Glutathione S-transferase HCH_06285 93 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83649053 Common - Disulfide bond formation protein DsbB HCH_06418 49 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 83643681 Nonpathogen - hypothetical protein HCH_00796 1 None None None 83643486 Common - Superfamily I DNA and RNA helicase HCH_00593 229 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 83649188 Common - ferric iron-catecholate outer membrane transporter HCH_06559 129 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 83645284 Common - predicted exporters of the RND superfamily HCH_02489 91 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 83645246 Common serS seryl-tRNA synthetase HCH_02449 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 83644845 Common - Lactoylglutathione lyase HCH_02021 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83647914 Common frr ribosome recycling factor HCH_05249 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 83643809 Nonpathogen - hypothetical protein HCH_00929 1 None None None 83649117 Common - predicted transcriptional regulator HCH_06486 133 COG0789 SoxR, Predicted transcriptional regulators Transcription 83644359 Common - hypothetical protein HCH_01511 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 83644989 Common - DnaJ-class molecular chaperone HCH_02170 22 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83646482 Common - Cation/multidrug efflux pump HCH_03760 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83647552 Nonpathogen - hypothetical protein HCH_04871 1 None None None 83649661 Common - hypothetical protein HCH_07059 21 None None None 83649154 Nonpathogen - GDSL-lilke lipase/acylhydrolase family protein HCH_06523 4 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 83647106 Nonpathogen - hypothetical protein HCH_04412 1 None None None 83646027 Common - FOG: TPR repeat HCH_03281 16 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83648109 Nonpathogen - hypothetical protein HCH_05454 1 None None None 83645749 Nonpathogen - hypothetical protein HCH_02990 1 None None None 83649633 Common - Large extracellular alpha-helical protein HCH_07028 86 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 83645852 Common - FOG: PAS/PAC domain HCH_03096 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648580 Common - gamma-glutamyl kinase HCH_05938 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 83644382 Common - SAM-dependent methyltransferase HCH_01534 172 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83647303 Nonpathogen - hypothetical protein HCH_04612 2 None None None 83644793 Nonpathogen - hypothetical protein HCH_01970 1 None None None 83646497 Common - Rhs family protein HCH_03775 57 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83648145 Common - hypothetical protein HCH_05492 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 83646969 Common - sigma 54-dependent transcriptional activator HCH_04272 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 83649246 Common - DNA-directed RNA polymerase specialized sigma subunit sigma24-like protein HCH_06622 157 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83645796 Nonpathogen - hypothetical protein HCH_03040 1 None None None 83646095 Common - Transglutaminase-like enzyme, putative cysteine protease HCH_03351 88 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83647841 Common - Flagellar GTP-binding protein HCH_05173 244 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 83645616 Common - Molybdopterin converting factor, small subunit HCH_02849 46 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 83649251 Common - Transcriptional regulator HCH_06627 173 COG0583 LysR, Transcriptional regulator Transcription 83649558 Common - Membrane protein related to metalloendopeptidase HCH_06951 56 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83646184 Common - Polyketide synthase modules and related protein HCH_03447 220 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83644790 Nonpathogen - hypothetical protein HCH_01967 1 None None None 83643038 Common - hypothetical protein HCH_00128 6 None None None 83648785 Common - Type II secretory pathway, component PulF HCH_06148 143 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 83643305 Common - hypothetical protein HCH_00404 11 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 83645502 Nonpathogen - Lipid A core - O-antigen ligase and related enzyme HCH_02727 6 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 83642934 Common glyS Glycyl-tRNA synthetase, beta subunit HCH_00021 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 83644805 Common - probable amine oxidoreductase, flavin-containing HCH_01982 18 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 83643315 Common - TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component HCH_00415 94 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83646666 Nonpathogen - hypothetical protein HCH_03957 1 None None None 83646929 Nonpathogen - hypothetical protein HCH_04232 1 None None None 83646366 Nonpathogen - hypothetical protein HCH_03636 1 None None None 83647060 Common ccmF cytochrome c-type biogenesis protein CcmF HCH_04364 130 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 83644488 Common - Signal transduction histidine kinase HCH_01644 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644208 Common - Rhodanese-related sulfurtransferase HCH_01353 116 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83646071 Common - DNA-binding protein H-NS HCH_03326 4 None None None 83644459 Common tbpA thiamin transporter substrate binding subunit HCH_01612 75 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 83647064 Common ccmB heme exporter protein CcmB HCH_04368 77 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 83645262 Common - RTX toxins and related Ca2+-binding protein HCH_02465 42 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 83645935 Common - AraC-type DNA-binding domain-containing protein HCH_03182 146 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645108 Common - hypothetical protein HCH_02295 7 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 83643590 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_00701 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83644452 Common - predicted esterase HCH_01605 95 COG0400 COG0400, Predicted esterase General function prediction only 83644904 Common - Rhs family protein HCH_02083 64 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83646368 Nonpathogen - hypothetical protein HCH_03638 1 None None None 83648946 Common recG ATP-dependent DNA helicase RecG HCH_06309 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 83646477 Common - putative amino-acid ABC transporter ATP-binding protein YecC HCH_03756 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 83643765 Common - hypothetical protein HCH_00883 12 None None None 83647048 Nonpathogen - hypothetical protein HCH_04352 1 None None None 83645846 Nonpathogen - hypothetical protein HCH_03090 1 None None None 83646607 Nonpathogen - hypothetical protein HCH_03891 1 None None None 83646007 Nonpathogen - hypothetical protein HCH_03258 1 None None None 83645787 Nonpathogen - hypothetical protein HCH_03031 1 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83648020 Nonpathogen - hypothetical protein HCH_05358 4 None None None 83647577 Common - Ribonucleotide reductase, alpha subunit HCH_04896 32 None None None 83645682 Nonpathogen - hypothetical protein HCH_02918 1 None None None 83648593 Common thiL thiamine-monophosphate kinase HCH_05952 185 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 83643117 Common - elongation factor P HCH_00211 215 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 83643262 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_00360 192 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83645945 Common - uncharacterized protein with a C-terminal OMP (outer membrane protein) domain HCH_03194 99 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 83644474 Nonpathogen - hypothetical protein HCH_01628 2 None None None 83644906 Common - Rhs family protein HCH_02086 71 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83648446 Common glcE glycolate oxidase FAD binding subunit HCH_05805 153 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83644561 Common pth peptidyl-tRNA hydrolase HCH_01723 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 83646407 Nonpathogen - hypothetical protein HCH_03676 1 None None None 83649346 Common - putative intracellular protease/amidase HCH_06730 59 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 83643094 Nonpathogen - hypothetical protein HCH_00187 7 None None None 83648678 Nonpathogen - hypothetical protein HCH_06038 1 None None None 83647001 Nonpathogen - hypothetical protein HCH_04304 1 None None None 83645464 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B HCH_02686 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 83645859 Common - predicted thiol oxidoreductase HCH_03103 59 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 83645581 Common - predicted helicase HCH_02813 75 COG1203 COG1203, Predicted helicases General function prediction only 83648746 Common - predicted phosphotransferase related to Ser/Thr protein kinase HCH_06108 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 83648065 Common - Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains) HCH_05406 138 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 83643772 Common - ABC-type polar amino acid transport system, ATPase component HCH_00890 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 83645815 Nonpathogen - hypothetical protein HCH_03059 1 None None None 83645975 Common - DNA-directed RNA polymerase specialized sigma subunit sigma24-like protein HCH_03224 111 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83645951 Nonpathogen - hypothetical protein HCH_03201 1 None None None 83645521 Common - predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis HCH_02746 138 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 83646825 Nonpathogen - hypothetical protein HCH_04125 1 None None None 83647818 Common - hypothetical protein HCH_05148 9 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 83644974 Common cysS cysteinyl-tRNA synthetase HCH_02154 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83643162 Common - dTDP-4-dehydrorhamnose reductase-like protein HCH_00259 209 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 83646005 Nonpathogen - hypothetical protein HCH_03256 1 None None None 83648392 Common - Enoyl-CoA hydratase/carnithine racemase HCH_05751 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83649488 Common - hypothetical protein HCH_06880 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 83646105 Nonpathogen - hypothetical protein HCH_03361 1 None None None 83648161 Nonpathogen - FOG: WD40-like repeat HCH_05509 14 COG1520 COG1520, FOG: WD40-like repeat Function unknown 83644669 Common aspA aspartate ammonia-lyase HCH_01841 234 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 83646586 Common - hypothetical protein HCH_03869 15 None None None 83644530 Common - Rhs family protein HCH_01692 61 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83646944 Common - hypothetical protein HCH_04247 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 161897901 Common - chromosome replication initiation inhibitor protein HCH_01593 101 COG0583 LysR, Transcriptional regulator Transcription 83647483 Nonpathogen - hypothetical protein HCH_04799 2 None None None 83643561 Common - hypothetical protein HCH_00671 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 83647031 Nonpathogen - hypothetical protein HCH_04335 1 None None None 83643436 Common - Chemotaxis protein histidine kinase and related kinase HCH_00541 221 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83647185 Common - ABC-type transport system involved in resistance to organic solvents, permease component HCH_04492 8 None None None 83648480 Common - Lipoprotein HCH_05840 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 83643837 Nonpathogen - hypothetical protein HCH_00959 1 None None None 83646883 Common - hypothetical protein HCH_04186 5 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 83647420 Nonpathogen - hypothetical protein HCH_04732 2 None None None 83643003 Nonpathogen - hypothetical protein HCH_00092 1 None None None 83646416 Common - 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit HCH_03687 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 83645921 Common - Transcriptional regulator HCH_03168 136 COG1802 GntR, Transcriptional regulators Transcription 83649648 Common - hypothetical protein HCH_07043 48 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 83644898 Nonpathogen - hypothetical protein HCH_02077 1 None None None 83645646 Common - hypothetical protein HCH_02881 38 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 83644311 Nonpathogen - hypothetical protein HCH_01463 1 None None None 83649084 Nonpathogen - Permease of the major facilitator superfamily HCH_06450 5 None None None 83643066 Nonpathogen - protein containing QXW lectin repeats HCH_00157 3 None None None 83645897 Common - Leucine-rich repeat (LRR) protein HCH_03144 41 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 83645543 Nonpathogen - hypothetical protein HCH_02770 1 None None None 83647292 Nonpathogen - hypothetical protein HCH_04601 1 None None None 83645661 Nonpathogen - hypothetical protein HCH_02897 3 None None None 83646519 Common - Transcriptional regulator HCH_03797 155 COG0583 LysR, Transcriptional regulator Transcription 83647043 Common - Membrane protein related to metalloendopeptidase HCH_04347 18 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83644143 Nonpathogen - hypothetical protein HCH_01286 1 None None None 83648152 Common - Protein related to penicillin acylase HCH_05500 61 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 83646534 Nonpathogen - hypothetical protein HCH_03813 1 None None None 83649483 Nonpathogen - hypothetical protein HCH_06875 1 None None None 83647676 Nonpathogen - hypothetical protein HCH_04999 2 None None None 83643946 Common tatB twin-arginine translocation protein TatB HCH_01075 47 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 83643250 Common - 6-phosphogluconolactonase HCH_00348 122 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 83646992 Nonpathogen - hypothetical protein HCH_04295 1 None None None 83643640 Common pstB phosphate ABC transporter, ATP-binding protein HCH_00753 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 83646337 Nonpathogen - hypothetical protein HCH_03607 1 None None None 83646690 Common - Small-conductance mechanosensitive channel HCH_03981 18 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83646999 Common - uncharacterized conserved protein, contains FHA domain HCH_04302 29 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 83643450 Common - Bacterial nucleoid DNA-binding protein HCH_00556 208 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83646709 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04001 43 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644269 Common - predicted transcriptional regulator HCH_01417 121 COG1959 COG1959, Predicted transcriptional regulator Transcription 83645707 Common - ABC-type metal ion transport system, periplasmic component/surface adhesin HCH_02945 55 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83645250 Common modB molybdate ABC transporter, permease protein HCH_02453 201 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 83645813 Nonpathogen - hypothetical protein HCH_03057 1 None None None 83646743 Nonpathogen - hypothetical protein HCH_04038 2 None None None 83647591 Common - predicted redox protein, regulator of disulfide bond formation HCH_04910 101 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83644043 Nonpathogen - hypothetical protein HCH_01177 5 None None None 83649192 Common - 2,3-dihydroxybenzoate-AMP ligase HCH_06564 222 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 83647776 Common - hypothetical protein HCH_05105 3 None None None 83647333 Common - Xanthine/uracil Permease HCH_04644 134 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 83645757 Common - Methionine aminopeptidase HCH_02999 218 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 83647642 Nonpathogen - hypothetical protein HCH_04963 3 None None None 83649532 Common - hypothetical protein HCH_06925 2 None None None 83647948 Common - hypothetical protein HCH_05285 98 COG1720 COG1720, Uncharacterized conserved protein Function unknown 83648995 Common metW methionine biosynthesis protein MetW HCH_06360 60 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83643471 Common djlA Dna-J like membrane chaperone protein HCH_00578 119 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 83648816 Common gmhA3 phosphoheptose isomerase HCH_06182 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 83649405 Common - Endoglucanase Y HCH_06791 20 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 83645199 Common asnB3 asparagine synthase (glutamine-hydrolyzing) HCH_02398 167 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83648969 Common - DNA or RNA helicase of superfamily II HCH_06333 123 COG4951 COG4951, Uncharacterized protein conserved in bacteria Function unknown 83643103 Common tehB SAM-dependent methyltransferase HCH_00196 35 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83643720 Nonpathogen - hypothetical protein HCH_00837 1 None None None 83644971 Common lpxH UDP-2,3-diacylglucosamine hydrolase HCH_02151 75 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 83644432 Common - hypothetical protein HCH_01585 63 COG2013 COG2013, Uncharacterized conserved protein Function unknown 83649412 Common ggt gamma-glutamyltranspeptidase HCH_06798 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 83648935 Nonpathogen - hypothetical protein HCH_06298 1 None None None 83643342 Common malG maltose transporter permease HCH_00442 157 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 83644685 Common arsC arsenate reductase HCH_01858 113 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 83647869 Common oadA1 pyruvate carboxylase subunit B HCH_05202 177 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 83646225 Common - Polyketide synthase modules and related protein HCH_03489 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83645958 Common katG catalase/peroxidase HPI HCH_03207 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 83646789 Common - Flagellar basal body rod protein HCH_04086 120 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 83648545 Common - hypothetical protein HCH_05905 16 COG3235 COG3235, Predicted membrane protein Function unknown 83645700 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_02938 111 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83649146 Common - hypothetical protein HCH_06516 9 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 83647486 Common - hypothetical protein HCH_04801 84 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 83644240 Common - hypothetical protein HCH_01387 30 COG3760 COG3760, Uncharacterized conserved protein Function unknown 83647094 Nonpathogen - hypothetical protein HCH_04400 1 None None None 83649130 Common - hypothetical protein HCH_06499 4 None None None 83645291 Common - hypothetical protein HCH_02499 19 COG3396 COG3396, Uncharacterized conserved protein Function unknown 83647876 Common - hypothetical protein HCH_05210 6 None None None 83646725 Common - uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems HCH_04019 107 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 83649392 Common - Phage-related tail protein HCH_06778 26 COG5283 COG5283, Phage-related tail protein Function unknown 83644185 Common - predicted transcriptional regulator HCH_01327 19 COG0789 SoxR, Predicted transcriptional regulators Transcription 83644524 Common - Acyl dehydratase HCH_01683 67 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83649361 Nonpathogen - hypothetical protein HCH_06746 1 None None None 83646574 Common - hypothetical protein HCH_03857 5 None None None 83649372 Nonpathogen - hypothetical protein HCH_06758 1 None None None 83646430 Common - Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain HCH_03703 160 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83642946 Common - putative translation factor (SUA5) HCH_00033 234 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 83645257 Nonpathogen - hypothetical protein HCH_02460 2 None None None 83644891 Nonpathogen - hypothetical protein HCH_02070 1 None None None 83646438 Common - FOG: CheY-like receiver HCH_03711 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643598 Nonpathogen - hypothetical protein HCH_00710 1 None None None 83648471 Common - Methyl-accepting chemotaxis protein HCH_05831 135 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643770 Common - ABC-type amino acid transport system, permease component HCH_00888 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83648730 Common - DnaJ-class molecular chaperone HCH_06092 19 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83646381 Common - hypothetical protein HCH_03651 19 None None None 83649098 Common - predicted integral membrane protein HCH_06465 15 COG5446 COG5446, Predicted integral membrane protein Function unknown 83644286 Common - Signal transduction histidine kinase HCH_01435 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83644812 Common - probable phage protein HCH_01988 11 None None None 83646000 Common - Rhs family protein HCH_03251 75 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83648953 Common - Transcriptional regulator HCH_06316 162 COG0583 LysR, Transcriptional regulator Transcription 83643653 Nonpathogen - VanZ like family protein HCH_00766 5 COG5652 COG5652, Predicted integral membrane protein Function unknown 83644737 Common - Uracil-DNA glycosylase HCH_01912 60 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 83644839 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_02015 69 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645078 Nonpathogen - hypothetical protein HCH_02262 1 None None None 83646784 Common flgB1 Flagellar basal body protein HCH_04081 8 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 83649449 Common - Exoribonuclease R HCH_06838 192 COG0557 VacB, Exoribonuclease R Transcription 83649508 Common - ABC-type oligopeptide transport system, ATPase component HCH_06900 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83646201 Common - Methyl-accepting chemotaxis protein HCH_03464 29 None None None 83642917 Nonpathogen - hypothetical protein HCH_00004 1 None None None 83646711 Nonpathogen - hypothetical protein HCH_04004 1 None None None 83648466 Common - Alkaline phosphatase HCH_05826 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 83647680 Common - putative translation factor (SUA5) HCH_05004 224 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 83646962 Nonpathogen - hypothetical protein HCH_04266 1 None None None 83643134 Common - GTPase SAR1 and related small G protein HCH_00229 18 COG2229 COG2229, Predicted GTPase General function prediction only 83644630 Common lepB signal peptidase I HCH_01798 209 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 83646845 Nonpathogen - hypothetical protein HCH_04144 1 None None None 83643568 Nonpathogen - hypothetical protein HCH_00678 1 None None None 83648645 Common accB acetyl-CoA carboxylase, biotin carboxyl carrier protein HCH_06005 185 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 83646214 Nonpathogen - hypothetical protein HCH_03478 1 None None None 83643607 Nonpathogen - hypothetical protein HCH_00719 1 None None None 83647583 Common - Nucleoside-diphosphate-sugar epimerase HCH_04902 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83647315 Common - FAD/FMN-containing dehydrogenase HCH_04625 194 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83643639 Common pstA phosphate ABC transporter, permease protein PtsA HCH_00752 227 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 83645055 Common asnC asparaginyl-tRNA synthetase HCH_02239 191 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83646085 Common - predicted nucleoside-diphosphate-sugar epimerase HCH_03341 44 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83645375 Common - hypothetical protein HCH_02593 5 None None None 83648582 Common rpmA 50S ribosomal protein L27 HCH_05940 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 83644171 Common - Methyl-accepting chemotaxis protein HCH_01314 178 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647862 Common fliE2 flagellar hook-basal body complex protein (FliE) HCH_05195 81 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 83643255 Nonpathogen - hypothetical protein HCH_00353 1 None None None 83647288 Common - AraC-type DNA-binding domain-containing protein HCH_04597 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646630 Common - probable endonuclease HCH_03919 22 None None None 83644468 Nonpathogen - hypothetical protein HCH_01622 1 None None None 83643070 Common - ABC-type proline/glycine betaine transport system, permease component HCH_00161 157 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 83644221 Common - hypothetical protein HCH_01367 16 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 83649091 Common - Glycosidase HCH_06457 160 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83643075 Common - RNA 3'-terminal-phosphate cyclase HCH_00166 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 83645225 Nonpathogen - hypothetical protein HCH_02427 1 None None None 83649438 Common - Beta-glucosidase-related Glycosidase HCH_06825 117 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 83649061 Nonpathogen - hypothetical protein HCH_06426 1 None None None 83649281 Common - protein of unknown function, DUF81 family HCH_06658 8 COG0730 COG0730, Predicted permeases General function prediction only 83646185 Common - Non-ribosomal peptide synthetase modules and related protein HCH_03448 194 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648207 Nonpathogen - hypothetical protein HCH_05558 1 None None None 83644210 Common - hypothetical protein HCH_01354 2 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 83649464 Common - Kef-type K+ transport system, predicted NAD-binding component HCH_06854 185 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 83644238 Common - hypothetical protein HCH_01385 18 None None None 83644998 Nonpathogen - hypothetical protein HCH_02180 1 None None None 83644626 Common mucB sigma factor algU negative regulatory protein MucB HCH_01792 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 83644153 Common - ABC-type sugar transport system, permease component HCH_01296 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83643963 Common - Transthyretin-like protein HCH_01093 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 83648454 Nonpathogen - hypothetical protein HCH_05813 1 None None None 83644429 Common - hypothetical protein HCH_10036 6 None None None 83645309 Common - Enoyl-[acyl-carrier-protein] reductase (NADH) HCH_02517 236 COG0623 FabI, Enoyl- acyl-carrier-protein 83645764 Common - predicted dienelactone hydrolase HCH_03006 49 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 83644010 Nonpathogen - probable two-component response regulator HCH_01143 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83643688 Common mnhC putative monovalent cation/H+ antiporter subunit C HCH_00803 88 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 83647124 Nonpathogen - hypothetical protein HCH_04429 1 None None None 83643128 Common recB exodeoxyribonuclease V, beta subunit HCH_00223 220 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 83644730 Common purN phosphoribosylglycinamide formyltransferase HCH_01905 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 83643554 Nonpathogen - hypothetical protein HCH_00664 1 None None None 83646230 Common - NADPH:quinone reductase and related Zn-dependent oxidoreductase HCH_03494 178 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83645576 Common - predicted carbamoyl transferase, NodU family HCH_02808 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 83646616 Nonpathogen - hypothetical protein HCH_03902 5 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 83644832 Nonpathogen - hypothetical protein HCH_02008 1 None None None 83647036 Nonpathogen - hypothetical protein HCH_04340 1 None None None 83648636 Common - Outer membrane protein HCH_05996 129 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83647632 Common tesA Lysophospholipase L1 HCH_04953 109 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 83649172 Nonpathogen - hypothetical protein HCH_06543 1 None None None 83644637 Common rumA 23S rRNA 5-methyluridine methyltransferase HCH_01806 200 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 83645495 Common - predicted xylanase/chitin deacetylase HCH_02719 95 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 83647824 Nonpathogen - hypothetical protein HCH_05154 1 None None None 83648683 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_06043 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83642983 Common hypE hydrogenase expression/formation protein HypE HCH_00072 150 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83644512 Common ugpQ Glycerophosphoryl diester phosphodiesterase HCH_01669 107 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 83647234 Nonpathogen - hypothetical protein HCH_04544 1 None None None 83648607 Common - hypothetical protein HCH_05966 22 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 83646150 Common - Sugar transferase involved in lipopolysaccharide synthesis HCH_03411 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 83647349 Nonpathogen - hypothetical protein HCH_04660 1 None None None 83644405 Nonpathogen - hypothetical protein HCH_01558 1 None None None 83645754 Nonpathogen - hypothetical protein HCH_02997 1 None None None 83648225 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_05575 61 None None None 83646030 Nonpathogen - hypothetical protein HCH_03284 1 None None None 83647211 Common ureA Urea amidohydrolase (urease) gamma subunit HCH_04521 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 83646931 Nonpathogen - hypothetical protein HCH_04234 1 None None None 83646766 Nonpathogen - hypothetical protein HCH_04061 1 None None None 83644105 Common pnp polynucleotide phosphorylase/polyadenylase HCH_01244 246 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 83649332 Common - hypothetical protein HCH_10032 4 None None None 83646509 Common - uncharacterized oxidoreductase, Fe-dependent alcohol dehydrogenase family HCH_03787 171 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 83646208 Common - predicted transcriptional regulator HCH_10013 32 COG3311 AlpA, Predicted transcriptional regulator Transcription 83644517 Common - uncharacterized protein, 4-oxalocrotonate tautomerase-like protein HCH_01674 17 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 83648765 Common - Anthranilate phosphoribosyltransferase HCH_06127 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 83644074 Common - Membrane-fusion protein HCH_01211 177 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83645526 Common - Nucleoside-diphosphate-sugar epimerase HCH_02751 91 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83647920 Common - hypothetical protein HCH_05257 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83644946 Common - hypothetical protein HCH_02127 7 None None None 83649561 Common - predicted integral membrane protein HCH_06955 24 COG5528 COG5528, Predicted integral membrane protein Function unknown 83646378 Common - elongation factor G HCH_03648 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 83644673 Common - uncharacterized conserved protein, contains double-stranded beta-helix domain HCH_01845 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 83647267 Common pheT phenylalanyl-tRNA synthetase subunit beta HCH_04574 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 83643516 Common - hypothetical protein HCH_00624 28 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 83648579 Common rpsT ribosomal protein S20 HCH_05937 116 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 83648002 Nonpathogen - hypothetical protein HCH_05340 1 None None None 83647529 Common - hypothetical protein HCH_04846 18 None None None 83648975 Common - Exonuclease III HCH_06339 193 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 83647057 Common - Cytochrome c biogenesis factor HCH_04361 36 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 83647881 Common - ABC-type arginine transport system, permease component HCH_05215 173 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 83646510 Common - Cation/multidrug efflux pump HCH_03788 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83643580 Nonpathogen - hypothetical protein HCH_00691 1 None None None 83644148 Nonpathogen - hypothetical protein HCH_01290 1 None None None 83646167 Common - Parvulin-like peptidyl-prolyl isomerase HCH_03429 21 None None None 83648086 Common - Rhodanese-related sulfurtransferase HCH_05430 54 None None None 83643735 Common - ABC-type proline/glycine betaine transport system, periplasmic components HCH_00852 68 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 83644307 Nonpathogen - hypothetical protein HCH_01457 1 None None None 83646128 Common - nitrous-oxide reductase HCH_03388 40 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 83643532 Common - Acyl-CoA dehydrogenase HCH_00641 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83646545 Nonpathogen - hypothetical protein HCH_03824 1 None None None 83644168 Common - hypothetical protein HCH_01311 21 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 83644490 Common serA D-3-phosphoglycerate dehydrogenase HCH_01646 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 83647534 Common - Phosphodiesterase/alkaline phosphatase D HCH_04851 56 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 83644563 Common prs Phosphoribosylpyrophosphate synthetase HCH_01726 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 83647683 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_05008 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83645490 Common - Sugar transferase involved in lipopolysaccharide synthesis HCH_02714 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 83648619 Common - Cell division protein HCH_05978 46 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 83643974 Common - uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein HCH_01105 96 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 83645388 Nonpathogen - hypothetical protein HCH_02606 1 None None None 83643914 Common - hypothetical protein HCH_01042 58 COG3025 COG3025, Uncharacterized conserved protein Function unknown 83646500 Nonpathogen - hypothetical protein HCH_03778 1 None None None 83646763 Nonpathogen - hypothetical protein HCH_04058 1 None None None 83648890 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_06253 54 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83643893 Common rpmG 50S ribosomal protein L33 HCH_01018 131 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 83645478 Common - Biopolymer transport protein HCH_02701 45 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83647143 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_04449 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83642927 Nonpathogen - hypothetical protein HCH_00014 1 None None None 83647178 Nonpathogen - hypothetical protein HCH_04485 1 None None None 83643846 Nonpathogen - hypothetical protein HCH_00969 1 None None None 83646529 Nonpathogen - hypothetical protein HCH_03808 1 None None None 83646641 Common gspK Type II secretory pathway, component PulK HCH_03930 48 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 83649355 Common - hypothetical protein HCH_06740 37 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 83642975 Nonpathogen - hypothetical protein HCH_00063 7 None None None 83647539 Common - Diacylglycerol kinase HCH_04856 91 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 83645480 Common lpxK tetraacyldisaccharide 4'-kinase HCH_02704 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 83644017 Nonpathogen - hypothetical protein HCH_01150 1 None None None 83645559 Nonpathogen - hypothetical protein HCH_02790 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83647693 Common - hypothetical protein HCH_05018 28 None None None 83649123 Nonpathogen - hypothetical protein HCH_06492 1 None None None 83643604 Nonpathogen - hypothetical protein HCH_00716 1 None None None 83644368 Common - hypothetical protein HCH_01520 4 None None None 83647478 Nonpathogen - hypothetical protein HCH_04794 1 None None None 83643740 Common - Threonine aldolase HCH_00857 103 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 83644031 Nonpathogen - hypothetical protein HCH_01164 1 None None None 83649174 Common - DNA repair protein HCH_06545 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83646290 Nonpathogen - hypothetical protein HCH_03558 1 None None None 83646871 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04174 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644750 Common panE2 2-dehydropantoate 2-reductase HCH_01927 110 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 83648171 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III HCH_05519 197 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 83646357 Common - Superfamily II DNA/RNA helicase, SNF2 family HCH_03627 120 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 83647908 Nonpathogen - hypothetical protein HCH_05244 1 None None None 83649622 Common - Xaa-Pro aminopeptidase HCH_07017 53 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 83644118 Common - hypothetical protein HCH_01259 13 None None None 83649364 Common - hypothetical protein HCH_06749 2 None None None 83643012 Common - Sulfite oxidase and related enzyme HCH_00101 95 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 83642921 Common gyrB DNA gyrase subunit B HCH_00008 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 83646720 Nonpathogen - hypothetical protein HCH_04014 1 None None None 83649238 Common - Long-chain acyl-CoA synthetases (AMP-forming) HCH_06614 213 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 83643984 Common argS arginyl-tRNA synthetase HCH_01116 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83644223 Common hmp Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 HCH_01369 108 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 83645963 Common - isocitrate dehydrogenase, NADP-dependent HCH_03212 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 83648912 Nonpathogen - hypothetical protein HCH_06276 1 None None None 83645136 Common aceA isocitrate lyase HCH_02323 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 83648424 Common - uncharacterized protein, possibly involved in aromatic compounds catabolism HCH_05783 77 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83643701 Common - protein containing bacterial Ig-like domains HCH_00818 31 None None None 83644299 Common - hypothetical protein HCH_01449 11 None None None 83647278 Common pepN Aminopeptidase N HCH_04587 158 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 83648488 Common - FOG: GGDEF domain HCH_05848 133 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83648266 Nonpathogen - hypothetical protein HCH_05618 6 None None None 83642955 Common prlC oligopeptidase A HCH_00043 124 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 83645540 Common - FOG: CBS domain HCH_02766 105 COG0517 COG0517, FOG: CBS domain General function prediction only 83646879 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_04182 120 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83643036 Common - short-chain alcohol dehydrogenase-like protein HCH_00126 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83646484 Nonpathogen - hypothetical protein HCH_03762 1 None None None 83643695 Common - Inhibitor of the KinA pathway to sporulation, predicted exonuclease HCH_00811 19 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 83647342 Common gap4 glyceraldehyde-3-phosphate dehydrogenase HCH_04653 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 83649036 Common - hypothetical protein HCH_06400 12 COG4095 COG4095, Uncharacterized conserved protein Function unknown 83648272 Common - hypothetical protein HCH_05624 20 None None None 83645436 Common cysB transcriptional regulator CysB HCH_02657 191 COG0583 LysR, Transcriptional regulator Transcription 83646267 Nonpathogen - hypothetical protein HCH_03534 1 None None None 83645210 Common rfbD dTDP-4-dehydrorhamnose reductase HCH_02410 174 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 83643507 Nonpathogen - hypothetical protein HCH_00615 1 None None None 83644331 Common - predicted redox protein, regulator of disulfide bond formation HCH_01483 28 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83645394 Common - hypothetical protein HCH_02614 195 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 83646302 Common - hypothetical protein HCH_03570 3 None None None 83647255 Common - hypothetical protein HCH_04563 3 None None None 83649668 Common - Tn7-like transposition protein B HCH_07066 47 None None None 83645517 Nonpathogen - protein of unknown function (DUF1555) HCH_02742 1 None None None 83647479 Nonpathogen - hypothetical protein HCH_04795 1 None None None 83649595 Nonpathogen - hypothetical protein HCH_06991 1 None None None 83648605 Common gltD glutamate synthase subunit beta HCH_05964 213 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 83645628 Common - hypothetical protein HCH_02861 6 COG5532 COG5532, Uncharacterized conserved protein Function unknown 83646908 Common - hypothetical protein HCH_04211 34 None None None 83643957 Nonpathogen - hypothetical protein HCH_01087 1 None None None 83648261 Nonpathogen - hypothetical protein HCH_05613 1 None None None 83647662 Common serC phosphoserine aminotransferase HCH_04982 115 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 83647806 Common - DNA-directed RNA polymerase specialized sigma subunit sigma24-like protein HCH_05136 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83646271 Common - hypothetical protein HCH_03538 2 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 83646087 Nonpathogen - probable DNA-binding protein containing LysTr domain HCH_03343 1 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 83647308 Common - predicted methylated DNA-protein cysteine methyltransferase HCH_04618 82 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 83649137 Common - hypothetical protein HCH_06506 56 COG1284 COG1284, Uncharacterized conserved protein Function unknown 83647701 Common hsdS Restriction endonuclease S subunit HCH_05028 75 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 83648960 Common - predicted ATPase HCH_06324 102 COG1485 COG1485, Predicted ATPase General function prediction only 83649005 Nonpathogen - hypothetical protein HCH_06370 1 None None None 83646342 Common - Signal transduction histidine kinase HCH_03612 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83646551 Nonpathogen feoA1 Fe2+ transport system protein A HCH_03833 4 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 83648831 Common rpmJ ribosomal protein L36 HCH_10026 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 161897897 Common - N-acetyl-anhydromuranmyl-L-alanine amidase HCH_01921 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 83646137 Nonpathogen - hypothetical protein HCH_03397 1 None None None 83644924 Common - isoprenoid biosynthesis protein with amidotransferase-like domain HCH_02105 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83646330 Common - Cytochrome P450 HCH_03600 59 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 83646753 Nonpathogen - hypothetical protein HCH_04048 1 None None None 83646624 Common - Transcriptional regulator HCH_03912 102 COG0583 LysR, Transcriptional regulator Transcription 83648184 Common - putative threonine efflux protein HCH_05532 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83643551 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00660 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83643909 Common - predicted membrane GTPase involved in stress response HCH_01037 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 83649424 Common - Phosphoglycerate dehydrogenase and related dehydrogenase HCH_06811 220 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 83643205 Common - FOG: CheY-like receiver HCH_00303 99 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83648380 Common - Zn-dependent Hydrolase, including glyoxylases HCH_05737 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83643441 Common - FOG: CheY-like receiver HCH_00546 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83648554 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase HCH_05913 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 83645510 Common - Acetyltransferase (isoleucine patch superfamily) HCH_10010 187 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 83648408 Common - uncharacterized enzyme involved in inositol metabolism HCH_05767 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 83649672 Common atpC F0F1 ATP synthase subunit epsilon HCH_07070 96 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 83649431 Nonpathogen - hypothetical protein HCH_06818 1 None None None 83644943 Common - predicted nucleoside-diphosphate-sugar epimerase HCH_02124 54 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83647774 Common - hypothetical protein HCH_05103 3 None None None 83645014 Common - Carbonic anhydrases/acetyltransferase, isoleucine patch superfamily HCH_02197 197 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 83648304 Common - probable phage protein HCH_05657 30 COG5281 COG5281, Phage-related minor tail protein Function unknown 83647992 Common - Ribonucleases G and E HCH_05330 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 83646917 Common - Glutaredoxin and related protein HCH_04220 11 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 83646147 Common - acetyl-CoA acetyltransferase HCH_03408 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83648131 Common - hypothetical protein HCH_05478 10 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 83644759 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01936 28 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645772 Nonpathogen - hypothetical protein HCH_03014 1 None None None 83646328 Nonpathogen - hypothetical protein HCH_03597 2 None None None 83644983 Common - Parvulin-like peptidyl-prolyl isomerase HCH_02164 172 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 83644151 Common - ABC-type sugar transport system, periplasmic component HCH_01294 96 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83645345 Common - Trk-type K+ transport system, membrane components HCH_02555 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 83649655 Nonpathogen - hypothetical protein HCH_07053 3 None None None 83647569 Common - DNA-directed RNA polymerase specialized sigma subunit sigma24-like protein HCH_04888 20 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83646799 Common - Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family 2 HCH_04098 221 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 83644600 Nonpathogen - hypothetical protein HCH_01765 1 None None None 83646988 Nonpathogen - hypothetical protein HCH_04291 2 None None None 83646870 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04173 101 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83649462 Common - Acetyltransferase HCH_06852 15 COG0456 RimI, Acetyltransferases General function prediction only 83647513 Nonpathogen - hypothetical protein HCH_04829 1 None None None 83645721 Common - Non-ribosomal peptide synthetase modules and related protein HCH_02960 209 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83643945 Common tatC Sec-independent protein translocase TatC HCH_01074 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 83643982 Common - Trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain HCH_01114 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83649455 Nonpathogen - hypothetical protein HCH_06845 1 None None None 83648004 Common - sulfate adenylyltransferase subunit 2 HCH_05342 136 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 83646547 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_03827 22 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83646299 Nonpathogen - hypothetical protein HCH_03567 1 None None None 83645425 Common - acyl-CoA synthetase HCH_02646 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83643683 Common - Fe-S oxidoreductase HCH_00798 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 83647132 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_04438 93 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83646530 Nonpathogen - hypothetical protein HCH_03809 1 None None None 83647544 Common - hypothetical protein HCH_04862 3 None None None 83647679 Nonpathogen - hypothetical protein HCH_05003 2 None None None 83649114 Common - Cytochrome c, mono- and diheme variants HCH_06483 12 COG3474 COG3474, Cytochrome c2 Energy production and conversion 83645655 Nonpathogen - hypothetical protein HCH_02890 1 None None None 83647193 Common - ABC-type uncharacterized transport system, periplasmic component HCH_04501 57 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 83648010 Common miaB tRNA-i(6)A37 thiotransferase enzyme MiaB HCH_05348 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 83643244 Common - hypothetical protein HCH_00342 11 None None None 83643988 Common - SAM-dependent methyltransferase HCH_01120 114 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83645217 Common - hypothetical protein HCH_02418 8 None None None 83646170 Nonpathogen - hypothetical protein HCH_03432 1 None None None 83645884 Nonpathogen - hypothetical protein HCH_03130 1 None None None 83643110 Common - ABC-type sugar transport system, permease component HCH_00204 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83645093 Common - predicted SAM-dependent methyltransferase HCH_02278 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 83648526 Common - UDP-N-acetylmuramyl pentapeptide synthase HCH_05887 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 83645862 Nonpathogen - protein containing HEAT repeats HCH_03106 1 None None None 83644878 Common - Permease of the major facilitator superfamily HCH_02057 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83645705 Common - FOG: WD40 repeat HCH_02943 20 None None None 83648803 Nonpathogen - hypothetical protein HCH_06168 1 None None None 83646851 Common - Glycosidase HCH_04152 33 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83645171 Common - hypothetical protein HCH_02360 3 None None None 83647711 Nonpathogen - hypothetical protein HCH_05038 1 None None None 83647561 Common - hypothetical protein HCH_04880 6 None None None 83644361 Nonpathogen - hypothetical protein HCH_01513 1 None None None 83647168 Common flgJ Muramidase (flagellum-specific) HCH_04474 67 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 83648967 Common - Transposase and inactivated derivatives HCH_06331 20 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83648389 Common - short-chain alcohol dehydrogenase-like protein HCH_05746 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83644045 Common istA1 transposase, IS21 family HCH_01179 74 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643161 Common - predicted signal transduction protein HCH_00258 42 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83643168 Common - MoxR-like ATPase HCH_00265 183 COG0714 COG0714, MoxR-like ATPases General function prediction only 83643790 Common - hypothetical protein HCH_00909 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 83646130 Common - hypothetical protein HCH_03390 58 COG1432 COG1432, Uncharacterized conserved protein Function unknown 83648163 Common - hypothetical protein HCH_05511 3 None None None 83643866 Common - hypothetical protein HCH_00991 34 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 83644500 Common - D-alanine-D-alanine ligase and related ATP-grasp enzyme HCH_01656 61 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 83649685 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA HCH_07083 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 83644636 Common cysM cysteine synthase B HCH_01805 228 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83644743 Common - predicted aspartyl protease HCH_01918 51 COG3577 COG3577, Predicted aspartyl protease General function prediction only 83646850 Nonpathogen - hypothetical protein HCH_04151 1 None None None 83645552 Common - hypothetical protein HCH_02782 3 None None None 83643121 Common - Pirin-related protein HCH_00215 148 COG1741 COG1741, Pirin-related protein General function prediction only 83644871 Common - hypothetical protein HCH_02050 23 COG5460 COG5460, Uncharacterized conserved protein Function unknown 83645869 Nonpathogen - hypothetical protein HCH_03114 1 None None None 83645449 Common - hypothetical protein HCH_02671 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 83646355 Common - hypothetical protein HCH_03626 4 None None None 83644860 Common - predicted amidohydrolase HCH_02036 122 COG0388 COG0388, Predicted amidohydrolase General function prediction only 83643446 Common - Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase HCH_00552 110 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 83648931 Common - Transcriptional regulator HCH_06293 182 COG0583 LysR, Transcriptional regulator Transcription 83644713 Nonpathogen - hypothetical protein HCH_01886 2 None None None 83646055 Common - Siderophore-interacting protein HCH_03310 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 83644212 Common - predicted redox protein, regulator of disulfide bond formation HCH_01357 90 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83646171 Nonpathogen - hypothetical protein HCH_03433 1 None None None 83646694 Nonpathogen - hypothetical protein HCH_03986 2 None None None 83649018 Common - Transposase and inactivated derivatives HCH_06383 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 83645598 Nonpathogen - hypothetical protein HCH_02830 1 None None None 83649490 Nonpathogen - hypothetical protein HCH_06881 1 None None None 83649504 Common - predicted Permease HCH_06895 42 COG0730 COG0730, Predicted permeases General function prediction only 83646303 Common - Thiol-disulfide isomerase and thioredoxins HCH_03571 15 None None None 83647917 Common rpsB 30S ribosomal protein S2 HCH_05253 226 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 83644378 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_01530 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83649318 Common - Signal transduction histidine kinase HCH_06700 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643354 Common - FOG: CheY-like receiver HCH_00454 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83645572 Common - ABC-type siderophore export system, fused ATPase and permease components HCH_02804 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 83647402 Common - predicted membrane protein HCH_04714 118 COG2855 COG2855, Predicted membrane protein Function unknown 83644867 Common - hypothetical protein HCH_02045 35 None None None 83645763 Common - AraC-type DNA-binding domain-containing protein HCH_03005 106 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83647670 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_04990 141 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83648885 Common hemL glutamate-1-semialdehyde-2,1-aminomutase HCH_06248 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 83647313 Common - Sugar (pentulose and hexulose) kinase HCH_04623 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 83645277 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_02484 106 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83645293 Common - Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II HCH_02501 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83645335 Common - hypothetical protein HCH_02544 161 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 83646838 Nonpathogen - hypothetical protein HCH_04138 1 None None None 83648496 Common - Dihydrofolate reductase HCH_05856 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 83649283 Nonpathogen - hypothetical protein HCH_06660 1 None None None 83643718 Common - hypothetical protein HCH_00835 12 None None None 83645795 Nonpathogen - hypothetical protein HCH_03039 7 None None None 83649228 Nonpathogen - hypothetical protein HCH_06603 1 None None None 83648194 Common - protein containing DnaJ domain HCH_05543 13 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83644292 Common soxR redox-sensitive transcriptional activator SoxR HCH_01441 111 COG0789 SoxR, Predicted transcriptional regulators Transcription 83646951 Common - Transposase and inactivated derivatives HCH_04254 49 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 83645714 Nonpathogen - hypothetical protein HCH_02952 1 None None None 83644183 Common - Transposase and inactivated derivatives HCH_01325 46 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644039 Nonpathogen - hypothetical protein HCH_01173 1 None None None 83643448 Common - Dihydroorotase and related cyclic amidoHydrolase HCH_00554 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 83644930 Common gltX glutamyl-tRNA synthetase HCH_02111 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83643171 Nonpathogen - hypothetical protein HCH_00268 1 None None None 83647717 Common - Methyl-accepting chemotaxis protein HCH_05044 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643082 Common - FOG: GGDEF domain HCH_00173 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643526 Common - Hemolysin-coregulated protein (uncharacterized) HCH_00635 25 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 83645235 Common accD acetyl-CoA carboxylase, carboxyl transferase, beta subunit HCH_02438 201 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 83647580 Common - Molybdopterin biosynthesis enzyme HCH_04899 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 83645549 Common - Rhs family protein HCH_02779 73 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83646323 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_03591 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83646678 Nonpathogen - hypothetical protein HCH_03969 1 None None None 83646609 Nonpathogen - hypothetical protein HCH_03893 1 None None None 83646614 Common - FOG: Ankyrin repeat HCH_03900 3 None None None 83647575 Nonpathogen - hypothetical protein HCH_04894 1 None None None 83648118 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05464 51 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646830 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain HCH_04130 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643288 Common - DnaK suppressor protein HCH_00387 4 None None None 83646946 Common - hypothetical protein HCH_04249 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 83649126 Common - Lactoylglutathione lyase HCH_06495 43 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 83648821 Nonpathogen - hypothetical protein HCH_06187 1 None None None 83645911 Common - hypothetical protein HCH_03158 4 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 83643557 Nonpathogen - hypothetical protein HCH_00667 1 None None None 83643621 Common - hypothetical protein HCH_00733 8 None None None 83648124 Common - putative threonine efflux protein HCH_05471 125 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83643237 Common - Fatty-acid desaturase HCH_00335 70 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 83647370 Common - hypothetical protein HCH_04681 9 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 83646016 Common - type III secretion system ATPase HCH_03268 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 83643870 Nonpathogen - hypothetical protein HCH_00995 2 None None None 83645049 Common - Glycosyltransferase involved in cell wall biogenesis HCH_02233 141 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83643460 Common - hypothetical protein HCH_00566 7 None None None 83649587 Common - ABC-type sugar transport system, periplasmic component HCH_06982 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83644127 Common - iron-sulfur cluster binding protein HCH_01269 96 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 83644104 Common rpsO ribosomal protein S15 HCH_01243 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 83643089 Common - predicted periplasmic lipoprotein HCH_00181 34 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 83648111 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_05456 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83644259 Common - hypothetical protein HCH_01406 36 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 83648287 Common - Transposase and inactivated derivatives HCH_05639 33 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83647027 Nonpathogen - hypothetical protein HCH_04331 1 None None None 83644111 Common livG leucine/isoleucine/valine transporter ATP-binding subunit HCH_01251 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83645403 Common - MoxR-like ATPase HCH_02623 92 COG0714 COG0714, MoxR-like ATPases General function prediction only 83644412 Common - predicted thiol oxidoreductase HCH_01565 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 83647853 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_05185 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83648375 Common rimK ribosomal protein S6 modification protein HCH_05732 47 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83643394 Nonpathogen - hypothetical protein HCH_00497 1 None None None 83644057 Common - Transcriptional regulator HCH_01192 180 COG0583 LysR, Transcriptional regulator Transcription 83648299 Nonpathogen - hypothetical protein HCH_05651 3 None None None 83647368 Common gumC chain length determinant protein HCH_04679 145 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 83645644 Nonpathogen - hypothetical protein HCH_02878 1 None None None 83643879 Common - delta-aminolevulinic acid dehydratase HCH_01004 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 83646710 Common - hypothetical protein HCH_04003 18 None None None 83649580 Common - Biopolymer transport protein HCH_06975 52 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 83643387 Common - 2OG-Fe(II) oxygenase superfamily protein HCH_00490 29 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 83643900 Nonpathogen - hypothetical protein HCH_01028 2 None None None 83647151 Common - hypothetical protein HCH_04457 71 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 83648216 Common - hypothetical protein HCH_05566 13 None None None 83643663 Common - NAD(P)H-nitrite reductase HCH_00777 232 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 83645020 Common - hypothetical protein HCH_02202 19 COG4544 COG4544, Uncharacterized conserved protein Function unknown 83647360 Nonpathogen - hypothetical protein HCH_04671 1 None None None 83648061 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_05402 177 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83649611 Nonpathogen - hypothetical protein HCH_07006 1 None None None 83647970 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase HCH_05307 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 83649106 Common cobL precorrin-6Y C5,15-methyltransferase (decarboxylating) HCH_06474 102 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 83646740 Nonpathogen - hypothetical protein HCH_04035 5 None None None 83647753 Common - NTP pyrophosphohydrolase containing a Zn-finger, probably nucleic-acid-binding HCH_05081 98 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 83644588 Common - Acetyl-CoA hydrolase HCH_01753 65 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 83643887 Nonpathogen - hypothetical protein HCH_01012 1 None None None 83648709 Common - hypothetical protein HCH_06070 11 None None None 83643538 Common - Cytochrome c553 HCH_00647 56 COG2863 COG2863, Cytochrome c553 Energy production and conversion 83643575 Common - hypothetical protein HCH_00685 17 None None None 83643181 Common fkpA FKBP-type peptidyl-prolyl cis-trans isomerases 1 HCH_00278 139 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 83643895 Common - DNA repair protein HCH_01020 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83647446 Common - hypothetical protein HCH_04761 6 None None None 83648292 Nonpathogen - hypothetical protein HCH_05644 2 None None None 83648891 Common - Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenases HCH_06255 38 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 83646052 Nonpathogen - hypothetical protein HCH_03307 1 None None None 83647734 Common - hypothetical protein HCH_05061 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 83648280 Nonpathogen - hypothetical protein HCH_05632 1 None None None 83648716 Common - Sugar kinase, ribokinase family HCH_06077 169 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83648412 Nonpathogen - hypothetical protein HCH_05771 1 None None None 83646920 Common - Truncated hemoglobin HCH_04223 25 COG2346 COG2346, Truncated hemoglobins General function prediction only 83643320 Common - Cell wall-associated Hydrolase (invasion-associated protein) HCH_00420 128 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 83647515 Common - glutamate-1-semialdehyde 2,1-aminomutase HCH_04831 236 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 83645004 Common - acetyl-CoA acetyltransferase HCH_02186 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83643220 Common - Transcriptional regulator HCH_00318 97 COG1802 GntR, Transcriptional regulators Transcription 83646440 Common - Signal transduction histidine kinase HCH_03714 225 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 83648906 Common - predicted membrane protein HCH_06269 81 COG0344 COG0344, Predicted membrane protein Function unknown 83644609 Common rplS 50S ribosomal protein L19 HCH_01775 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 83648851 Common rplD Ribosomal protein L4 HCH_06216 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 83643197 Common argH argininosuccinate lyase HCH_00294 230 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 83643412 Common - Transcriptional regulator HCH_00516 157 COG0583 LysR, Transcriptional regulator Transcription 83645440 Common thrH phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein HCH_02661 21 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 83648238 Common - FOG: TPR repeat HCH_05589 19 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83647973 Common - predicted NTP binding protein (contains STAS domain) HCH_05310 2 None None None 83648413 Common - Transcriptional regulator HCH_05772 92 COG1737 RpiR, Transcriptional regulators Transcription 83648729 Common - hypothetical protein HCH_06091 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 83647214 Common ureE Urease accessory protein UreE HCH_04524 67 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 83646429 Common - Response regulator containing a CheY-like receiver domain and an HD-GYP domain HCH_03702 152 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83643545 Common - Response regulator containing a CheY-like receiver domain and an HD-GYP domain HCH_00654 121 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83646814 Nonpathogen - hypothetical protein HCH_04114 1 None None None 83644581 Common - Membrane-associated phospholipid phosphatase HCH_01745 50 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 83645901 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_03148 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83643655 Common - uncharacterized protein involved in cysteine biosynthesis HCH_00768 43 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 83645354 Nonpathogen - citrate synthase-like protein HCH_02564 6 None None None 83649298 Nonpathogen - hypothetical protein HCH_06678 2 None None None 83647419 Common smc chromosome segregation protein SMC HCH_04731 189 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83649381 Common - phage major capsid protein, P2 family HCH_06766 22 None None None 83647617 Common - predicted UDP-glucose 6-dehydrogenase HCH_04938 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 83649476 Nonpathogen - hypothetical protein HCH_06868 1 None None None 83645027 Common potA putrescine/spermidine ABC transporter ATPase protein HCH_02209 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83644803 Common - predicted aminopeptidase HCH_01980 65 COG2234 Iap, Predicted aminopeptidases General function prediction only 83647627 Common - putative Zn-dependent protease HCH_04948 135 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83646489 Nonpathogen - hypothetical protein HCH_03767 1 None None None 83644025 Common - Sugar phosphate isomerases/epimerase HCH_01158 71 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 83645509 Common - Coenzyme F390 synthetase HCH_02734 94 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 83647409 Common - Negative regulator of flagellin synthesis (anti-sigma28 factor) HCH_04721 21 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 83647764 Common - hypothetical protein HCH_05093 2 None None None 83645890 Common - hypothetical protein HCH_03136 22 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 83648863 Common rplK ribosomal protein L11 HCH_06228 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 83649210 Common - Mg2+ and Co2+ transporters HCH_06583 106 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 83644482 Common - Signal transduction histidine kinase HCH_01636 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83648763 Common trpE anthranilate synthase component I HCH_06125 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 83646745 Common - predicted amidohydrolase HCH_04040 182 COG0388 COG0388, Predicted amidohydrolase General function prediction only 83643139 Nonpathogen - hypothetical protein HCH_00234 1 None None None 83647329 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase HCH_04640 175 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83649338 Common - Zn-ribbon-containing, possibly nucleic-acid-binding protein HCH_06721 12 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 83644824 Common - probable poly(3-hydroxybutyrate) depolymerase precursor HCH_02000 12 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 83648401 Common - hypothetical protein HCH_05760 23 None None None 83649217 Common - FOG: EAL domain HCH_06590 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83645270 Nonpathogen - hypothetical protein HCH_02474 1 None None None 83644293 Common - predicted flavoprotein HCH_01442 102 COG0431 COG0431, Predicted flavoprotein General function prediction only 83644387 Common pldB Lysophospholipase HCH_01539 52 COG2267 PldB, Lysophospholipase Lipid metabolism 83644684 Common - Multimeric flavodoxin WrbA HCH_01857 120 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 83648847 Common rplV 50S ribosomal protein L22 HCH_06212 228 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 83646927 Nonpathogen - hypothetical protein HCH_04230 2 None None None 83647130 Nonpathogen - hypothetical protein HCH_04436 1 None None None 83648775 Common - uncharacterized membrane protein HCH_06137 10 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 83649328 Nonpathogen - hypothetical protein HCH_06711 2 None None None 83648540 Common petA ubiquinol-cytochrome c reductase, iron-sulfur subunit HCH_05900 93 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 83643213 Common - hypothetical protein HCH_00311 18 None None None 83643027 Common - hypothetical protein HCH_00116 11 None None None 83646801 Common - ThiS family protein HCH_04100 10 None None None 83648218 Common - AraC-type DNA-binding domain-containing protein HCH_05568 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83645042 Common rluA2 Pseudouridylate synthases, 23S RNA-specific HCH_02226 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83643796 Common atpG1 F0F1-type ATP synthase, gamma subunit HCH_00915 53 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 83645103 Nonpathogen - hypothetical protein HCH_02290 1 None None None 83645428 Common - 3-oxoacyl-(acyl carrier protein) synthase III HCH_02649 198 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 83648433 Common - hypothetical protein HCH_05792 24 None None None 83644596 Common - ABC-type spermidine/putrescine transport system, ATPase components HCH_01761 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83645736 Nonpathogen - hypothetical protein HCH_02977 1 None None None 83644329 Common - putative Ser protein kinase HCH_01481 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 83644241 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase HCH_01388 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 83646869 Common hutH histidine ammonia-lyase HCH_04172 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 83647239 Nonpathogen - hypothetical protein HCH_04549 1 None None None 83646653 Common - Acyl-CoA dehydrogenase HCH_03943 171 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83643777 Common - hypothetical protein HCH_00895 14 None None None 83646687 Common - hypothetical protein HCH_03978 8 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83647890 Common - Kef-type K+ transport system, predicted NAD-binding component HCH_05225 76 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 83648136 Common - Transcriptional regulator HCH_05483 159 COG0583 LysR, Transcriptional regulator Transcription 83649377 Common - hypothetical protein HCH_06761 13 None None None 83647148 Common - hypothetical protein HCH_04454 59 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 83642963 Common - hypothetical protein HCH_00051 54 COG3346 COG3346, Uncharacterized conserved protein Function unknown 83646119 Common - Hemolysin activation/secretion protein HCH_03379 66 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 83644691 Common - hypothetical protein HCH_01864 15 None None None 83647416 Common - hypothetical protein HCH_04728 17 None None None 83645604 Common - Transposase and inactivated derivatives HCH_02835 33 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 83645916 Common dapA1 dihydrodipicolinate synthase HCH_03163 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 83644886 Nonpathogen - hypothetical protein HCH_02065 1 None None None 83648712 Nonpathogen - hypothetical protein HCH_06073 1 None None None 83648241 Nonpathogen - hypothetical protein HCH_05592 1 None None None 83648047 Common - predicted ATPase or kinase HCH_05388 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 83644953 Nonpathogen - hypothetical protein HCH_02134 1 None None None 83647399 Common - FOG: TPR repeat HCH_04711 14 None None None 83648720 Common - ABC-type sugar transport system, permease components HCH_06081 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83648273 Common - Site-specific recombinase HCH_05625 136 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 83647899 Common mutS DNA mismatch repair protein HCH_05234 203 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 83646140 Common - Transposase and inactivated derivatives HCH_03400 33 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83648654 Common - Thiol-disulfide isomerase and thioredoxins HCH_06014 23 None None None 83647937 Common - Glycosyltransferase HCH_05274 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83646262 Common - predicted transcriptional regulator HCH_03527 84 COG1959 COG1959, Predicted transcriptional regulator Transcription 83644558 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01720 28 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646022 Nonpathogen - hypothetical protein HCH_03275 1 None None None 83648840 Common rplE 50S ribosomal protein L5 HCH_06205 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 83646246 Nonpathogen - hypothetical protein HCH_03510 1 None None None 83649497 Common - hypothetical protein HCH_06889 16 None None None 83649601 Common - ADP-ribose pyrophosphatase HCH_06996 104 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83643933 Common rpiA ribose-5-phosphate isomerase A HCH_01062 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 83646605 Nonpathogen - hypothetical protein HCH_03888 1 None None None 83649055 Common - flagellar basal body-associated protein FliL-like protein HCH_06420 21 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 83643851 Common ald alanine dehydrogenase HCH_00974 164 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 83646278 Common - hypothetical protein HCH_03546 56 COG1479 COG1479, Uncharacterized conserved protein Function unknown 83643421 Common - short chain dehydrogenase HCH_00526 226 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83646151 Nonpathogen - hypothetical protein HCH_03412 2 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83649579 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06974 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644401 Common - hypothetical protein HCH_01554 31 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 83644355 Common - phytanoyl-CoA deoxygenase family protein HCH_01507 36 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83649537 Nonpathogen - hypothetical protein HCH_06930 1 None None None 83645147 Common mutT NTP pyrophosphohydrolase including oxidative damage repair enzyme HCH_02334 54 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83645906 Nonpathogen - hypothetical protein HCH_03154 1 None None None 83649075 Common - hypothetical protein HCH_06440 33 COG3382 COG3382, Uncharacterized conserved protein Function unknown 83643528 Nonpathogen - hypothetical protein HCH_00637 1 None None None 83645674 Nonpathogen - hypothetical protein HCH_02910 2 None None None 83648505 Common ispA Geranylgeranyl pyrophosphate synthase HCH_05865 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 83644392 Nonpathogen - hypothetical protein HCH_01544 1 None None None 83646409 Common - hypothetical protein HCH_03679 27 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 83647727 Common - Alcohol dehydrogenase, class IV HCH_05054 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 83645126 Common - Sugar kinase, ribokinase family HCH_02313 166 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83645536 Common - Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) HCH_02762 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 83643629 Nonpathogen - hypothetical protein HCH_00742 1 None None None 83649520 Common - Transcriptional regulator HCH_06913 126 COG1609 PurR, Transcriptional regulators Transcription 83647386 Common - predicted membrane protein involved in D-alanine export HCH_04698 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 83649070 Nonpathogen - hypothetical protein HCH_06435 1 None None None 83644783 Nonpathogen - hypothetical protein HCH_01960 1 None None None 83649236 Common - hypothetical protein HCH_06612 8 None None None 83648187 Common - predicted transcriptional regulator HCH_05536 35 COG0640 ArsR, Predicted transcriptional regulators Transcription 83648323 Nonpathogen - hypothetical protein HCH_05678 1 None None None 83645663 Nonpathogen - hypothetical protein HCH_02899 1 None None None 83648460 Nonpathogen - hypothetical protein HCH_05819 1 None None None 83643938 Nonpathogen - hypothetical protein HCH_01067 1 None None None 83645854 Nonpathogen - hypothetical protein HCH_03098 8 None None None 83644664 Nonpathogen - hypothetical protein HCH_01835 1 None None None 83645383 Nonpathogen - protein containing tetratricopeptide repeats HCH_02601 6 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83648346 Nonpathogen - hypothetical protein HCH_05700 1 None None None 83644535 Nonpathogen - hypothetical protein HCH_01697 1 None None None 83649533 Nonpathogen - hypothetical protein HCH_06926 1 None None None 83647620 Common - predicted acyltransferase HCH_04941 94 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83649630 Common - predicted metal-dependent membrane protease HCH_07025 17 None None None 83645466 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D HCH_02688 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 83646311 Nonpathogen - hypothetical protein HCH_03579 3 None None None 83648447 Common - FAD/FMN-containing dehydrogenase HCH_05806 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83649626 Nonpathogen - hypothetical protein HCH_07021 1 None None None 83646392 Common phy 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) HCH_03662 18 COG4247 Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) Lipid metabolism 83645454 Common - Ammonia permease HCH_02676 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 83647492 Common - predicted membrane protein HCH_04808 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 83648676 Nonpathogen - Nitroreductase HCH_06036 2 COG0778 NfnB, Nitroreductase Energy production and conversion 83645248 Common - hypothetical protein HCH_02451 23 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 83645264 Common - ABC-type sugar transport system, periplasmic component HCH_02467 108 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83644472 Common - Transcriptional regulator HCH_01626 162 COG0583 LysR, Transcriptional regulator Transcription 83643563 Common - Chemotaxis protein CheC, inhibitor of MCP methylation HCH_00673 28 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 83648948 Common - Nucleoside-diphosphate-sugar epimerase HCH_06311 61 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83646093 Nonpathogen - hypothetical protein HCH_03349 1 None None None 83645690 Common - Permease of the major facilitator superfamily HCH_02927 136 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83644435 Nonpathogen - hypothetical protein HCH_01587 1 None None None 83648556 Common ilvH acetolactate synthase 3 regulatory subunit HCH_05915 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 83645874 Common - Transcriptional regulator HCH_03119 99 COG0583 LysR, Transcriptional regulator Transcription 83647996 Common - Actin-like ATPase involved in cell morphogenesis HCH_05334 231 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 83648338 Nonpathogen - hypothetical protein HCH_05692 1 None None None 83649279 Nonpathogen - hypothetical protein HCH_06656 1 None None None 83643883 Nonpathogen - hypothetical protein HCH_01008 1 None None None 83645029 Common - Collagenase and related protease HCH_02211 51 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 83644628 Common mucD serine protease MucD precursor HCH_01795 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83648200 Common - Signal transduction histidine kinase HCH_05549 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83643069 Common - ABC-type proline/glycine betaine transport system, ATPase components HCH_00160 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 83643767 Nonpathogen - hypothetical protein HCH_00885 4 None None None 83647044 Common - predicted O-methyltransferase HCH_04348 103 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 83647066 Common - hypothetical protein HCH_04370 9 None None None 83648623 Common - predicted esterase of the alpha-beta hydrolase superfamily HCH_05982 43 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83643541 Common - delta-aminolevulinic acid dehydratase HCH_00650 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 83644486 Common - hypothetical protein HCH_01641 77 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 83643257 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00355 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647377 Nonpathogen - hypothetical protein HCH_04689 1 None None None 83644575 Common - Transcriptional regulator HCH_01739 18 COG1309 AcrR, Transcriptional regulator Transcription 83645933 Common - hypothetical protein HCH_03180 21 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 83648787 Common - FOG: TPR repeat HCH_06150 27 COG0457 NrfG, FOG: TPR repeat General function prediction only 83648951 Common rpoZ DNA-directed RNA polymerase, omega subunit HCH_06314 119 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 83645239 Common purF amidophosphoribosyltransferase HCH_02442 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 83645504 Common - Membrane protein involved in the export of O-antigen and teichoic acid HCH_02729 63 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83647208 Common - Branched-chain amino acid ABC-type transport system, permease components HCH_04517 158 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83647062 Common - Heme exporter protein D HCH_04366 5 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 83647579 Nonpathogen - hypothetical protein HCH_04898 2 COG1396 HipB, Predicted transcriptional regulators Transcription 83643874 Common - Transcriptional regulator HCH_00999 13 COG1309 AcrR, Transcriptional regulator Transcription 83648308 Common - hypothetical protein HCH_05661 11 None None None 83643510 Nonpathogen - hypothetical protein HCH_00618 3 None None None 83643755 Common lpdA1 dihydrolipoamide dehydrogenase HCH_00873 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83647310 Common - nucleotide-binding protein HCH_04620 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 83644791 Common - predicted phosphatase HCH_01968 7 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 83646880 Nonpathogen draG ADP-ribosylglycohydrolase HCH_04183 4 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 83644423 Nonpathogen - hypothetical protein HCH_01576 4 None None None 83643993 Nonpathogen - hypothetical protein HCH_01125 2 None None None 83643452 Common - hypothetical protein HCH_00558 4 None None None 83646924 Nonpathogen - hypothetical protein HCH_04227 1 None None None 83645035 Common - Membrane-fusion protein HCH_02217 176 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83642948 Nonpathogen - ferric pseudobactins receptor protein RF5-like protein HCH_00034 1 None None None 83645976 Nonpathogen - hypothetical protein HCH_03226 1 None None None 83647104 Common norB Nitric oxide reductase large subunit HCH_04410 109 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 83644901 Common - Rhs family protein HCH_02080 74 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83646413 Common - Serine/threonine protein kinase HCH_03684 70 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83648485 Common - uncharacterized plant Iojap protein HCH_05845 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 83643520 Common - hypothetical protein HCH_00628 3 COG2259 COG2259, Predicted membrane protein Function unknown 83644100 Common nusA transcription elongation factor NusA HCH_01238 218 COG0195 NusA, Transcription elongation factor Transcription 83644471 Common - predicted Permease HCH_01625 38 COG0730 COG0730, Predicted permeases General function prediction only 83646078 Common - Thiol-disulfide isomerase and thioredoxins HCH_03334 150 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83643382 Common - Di- and tricarboxylate transporters HCH_00483 129 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 83645597 Nonpathogen - hypothetical protein HCH_02829 1 None None None 83645241 Nonpathogen - hypothetical protein HCH_02444 1 None None None 83647691 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_05016 178 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83647339 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_04650 158 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83643830 Common maiA maleylacetoacetate isomerase HCH_00952 109 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83645992 Common - putative type III export protein YscD HCH_03242 9 None None None 83647092 Nonpathogen - hypothetical protein HCH_04397 1 None None None 83646692 Common - predicted oxidoreductase (related to aryl-alcohol dehydrogenase) HCH_03983 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83648805 Common - Glycosyltransferase HCH_06170 117 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83645752 Nonpathogen - hypothetical protein HCH_02993 1 None None None 83646339 Nonpathogen - hypothetical protein HCH_03609 1 None None None 83648661 Common - Acyl-CoA dehydrogenase HCH_06021 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83643948 Common hisE Phosphoribosyl-ATP pyrophosphohydrolase HCH_01078 174 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 83649022 Common - hypothetical protein HCH_06387 10 None None None 83643760 Common - predicted branched-chain amino acid permease (azaleucine resistance) HCH_00878 111 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 83643970 Nonpathogen - hypothetical protein HCH_01100 1 None None None 83643979 Nonpathogen - hypothetical protein HCH_01111 1 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 83645742 Nonpathogen - hypothetical protein HCH_02983 1 None None None 83645817 Common - putative intracellular protease/amidase HCH_03061 155 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 83645785 Nonpathogen - hypothetical protein HCH_03029 1 None None None 83649485 Nonpathogen - hypothetical protein HCH_06877 1 None None None 83648039 Common hflC HflC protein HCH_05380 204 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83648067 Common - DNA repair photolyase HCH_05408 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 83645923 Common - AraC-type DNA-binding domain-containing protein HCH_03170 28 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646866 Common hutI imidazolonepropionase HCH_04169 112 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 83648700 Common - hypothetical protein HCH_06061 4 COG2520 COG2520, Predicted methyltransferase General function prediction only 83647839 Common fliA flagellar biosynthesis sigma factor FliA HCH_05171 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 83644061 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01196 17 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647481 Nonpathogen - hypothetical protein HCH_04797 1 None None None 83647099 Common - Parvulin-like peptidyl-prolyl isomerase HCH_04404 149 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 83647527 Common - Acetyltransferase, including N-acetylases of ribosomal protein HCH_04844 82 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83645618 Common - Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family 2 HCH_02851 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 83645648 Nonpathogen - hypothetical protein HCH_02883 1 None None None 83645956 Common - Signal transduction histidine kinase, nitrogen specific HCH_03205 24 None None None 83648440 Common - Transcriptional regulator HCH_05799 76 COG1309 AcrR, Transcriptional regulator Transcription 83645332 Common - hypothetical protein HCH_02541 10 None None None 83644003 Common - uncharacterized protein contain chitin-binding domain type 3 HCH_01135 21 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 83649441 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase components HCH_06829 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83645369 Common - hypothetical protein HCH_02586 6 None None None 83649358 Common - hypothetical protein HCH_06743 15 None None None 83643749 Common - Permease of the major facilitator superfamily HCH_00867 70 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83646458 Nonpathogen - hypothetical protein HCH_03734 1 None None None 83648767 Common - Transcriptional regulator HCH_06129 154 COG0583 LysR, Transcriptional regulator Transcription 83645697 Nonpathogen - hypothetical protein HCH_02935 3 COG5500 COG5500, Predicted integral membrane protein Function unknown 83649341 Common - Glutathione S-transferase HCH_06725 82 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83649160 Common apaH diadenosine tetraphosphatase HCH_06531 99 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 83643648 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00761 40 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643788 Common - Transcriptional regulator HCH_00907 165 COG0583 LysR, Transcriptional regulator Transcription 83643367 Nonpathogen - protein containing PDZ domain HCH_00467 3 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83646029 Nonpathogen - hypothetical protein HCH_03283 1 None None None 83644651 Common - hypothetical protein HCH_01822 12 None None None 83644335 Common htpX1 Zn-dependent protease with chaperone function HCH_01488 15 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 83649646 Nonpathogen - hypothetical protein HCH_07041 1 None None None 83649202 Common - 2,3-dihydroxybenzoate-2,3-dehydrogenase HCH_06575 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83646288 Nonpathogen - hypothetical protein HCH_03556 1 None None None 83646035 Common - IS116/IS110/IS902 family transposase HCH_03289 56 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 83647549 Nonpathogen - hypothetical protein HCH_04869 1 None None None 83644046 Nonpathogen - hypothetical protein HCH_01180 6 None None None 83644022 Nonpathogen - hypothetical protein HCH_01155 1 None None None 83644544 Common - hypothetical protein HCH_01706 65 COG1469 COG1469, Uncharacterized conserved protein Function unknown 83644709 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_01882 89 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83645636 Nonpathogen - hypothetical protein HCH_02870 1 None None None 83647811 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase HCH_05141 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83648658 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_06018 213 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83644125 Common - FAD/FMN-containing dehydrogenase HCH_01266 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83646211 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03474 85 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83646804 Common - hypothetical protein HCH_04103 5 None None None 83647748 Common - putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzyme HCH_05075 32 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83648405 Common - short chain dehydrogenase HCH_05764 79 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83645991 Nonpathogen - hypothetical protein HCH_03241 1 None None None 83648543 Common - Mg-dependent DNase HCH_05903 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 83646218 Nonpathogen - hypothetical protein HCH_03482 1 None None None 83649676 Common atpH F0F1 ATP synthase subunit delta HCH_07075 184 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 83643005 Common - cell wall surface anchor family protein HCH_00094 43 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 83643123 Common pepD putative aminoacyl-histidine dipeptidase PepD HCH_00218 54 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 83644752 Nonpathogen - hypothetical protein HCH_01929 1 None None None 83643612 Common - Phosphoglycerate dehydrogenase and related dehydrogenase HCH_00724 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 83647867 Nonpathogen - hypothetical protein HCH_05200 1 None None None 83644233 Common - Rhs family protein HCH_01380 44 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83645135 Nonpathogen - hypothetical protein HCH_02322 2 None None None 83643789 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_00908 94 None None None 83646227 Common - Polyketide synthase modules and related protein HCH_03491 229 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83649065 Common - predicted transcription regulator, contains HTH domain (MarR family) HCH_06430 24 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 83649570 Common glpK glycerol kinase HCH_06965 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 83644542 Common hisI2 Phosphoribosyl-AMP cyclohydrolase HCH_10001 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 83647322 Common - AraC-type DNA-binding domain-containing protein HCH_04634 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83644085 Common grpE Molecular chaperone GrpE (heat shock protein) HCH_01223 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 83644704 Common rpoS nonessential primary sigma factor HCH_01877 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 83643291 Common - probable phage protein HCH_00390 10 None None None 83648562 Common comL DNA uptake lipoprotein HCH_05922 119 COG4105 ComL, DNA uptake lipoprotein General function prediction only 83643782 Nonpathogen - hypothetical protein HCH_00901 1 None None None 83645145 Common - hypothetical protein HCH_02332 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 83648052 Common - Flagellar motor protein HCH_05393 109 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83647229 Nonpathogen - hypothetical protein HCH_04539 1 None None None 83644163 Nonpathogen - hypothetical protein HCH_01306 2 None None None 83646308 Nonpathogen - hypothetical protein HCH_03576 1 None None None 83649159 Nonpathogen - hypothetical protein HCH_06530 2 None None None 83646566 Common - Methyl-accepting chemotaxis protein HCH_03848 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83643981 Common - Outer membrane phospholipase A HCH_01113 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 83645064 Nonpathogen - hypothetical protein HCH_02248 2 None None None 83647978 Common - predicted sugar phosphate isomerase involved in capsule formation HCH_05315 182 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 83645166 Common - tRNA-dihydrouridine synthase A HCH_02353 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 83647715 Common - predicted membrane protein HCH_05042 12 COG2314 XynA, Predicted membrane protein Function unknown 83647696 Common - Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster HCH_05021 68 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 83647929 Common neuA CMP-N-acetylneuraminic acid synthetase HCH_05265 54 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 83647922 Common - Arsenate reductase and related protein, glutaredoxin family HCH_05258 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 83644668 Common gmhA1 phosphoheptose isomerase HCH_01840 142 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 83648595 Common ribH riboflavin synthase subunit beta HCH_05954 227 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 83649663 Common - Transposase and inactivated derivatives HCH_07061 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83649516 Common - ABC-type sugar transport system, permease component HCH_06908 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83643322 Nonpathogen - hypothetical protein HCH_00422 1 None None None 83646196 Common - uncharacterized protein conserved in bacteria containing thioredoxin-like domain HCH_03459 19 COG4759 COG4759, Uncharacterized protein conserved in bacteria containing thioredoxin-like domain Posttranslational modification, protein turnover, chaperones 83648396 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_05755 183 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83647732 Common - predicted metal-dependent Hydrolase related to alanyl-tRNA synthetase HxxxH domain HCH_05059 240 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 83647122 Nonpathogen - hypothetical protein HCH_04428 1 None None None 83648202 Nonpathogen - hypothetical protein HCH_05552 1 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 83646576 Common sdaA L-serine ammonia-lyase HCH_03859 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 83647635 Common - Universal stress protein UspA and related nucleotide-binding protein HCH_04956 71 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83643501 Nonpathogen - hypothetical protein HCH_00608 1 None None None 83648513 Common secA preprotein translocase subunit SecA HCH_05873 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 83649530 Common - AraC-type DNA-binding domain-containing protein HCH_06923 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83648868 Common - hypothetical protein HCH_06232 8 None None None 83648371 Common - probable transcriptional regulator HCH_05728 14 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 83644893 Nonpathogen - hypothetical protein HCH_02072 1 None None None 83643403 Common - hypothetical protein HCH_00506 2 None None None 83647832 Common - ATPase involved in chromosome partitioning HCH_05163 221 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83645360 Nonpathogen - hypothetical protein HCH_02570 1 None None None 83648045 Nonpathogen - hypothetical protein HCH_05386 1 None None None 83644265 Common sufD FeS assembly protein SufD HCH_01413 168 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 83648464 Common - Lactoylglutathione lyase HCH_05824 51 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83648011 Common - Phosphate starvation-inducible protein PhoH, predicted ATPase HCH_05349 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 83646699 Common - Na+/alanine symporter HCH_03992 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 83643469 Common - 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase HCH_00576 194 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 83644658 Common - Transcriptional regulator HCH_01829 175 COG0583 LysR, Transcriptional regulator Transcription 83646867 Common hutG formimidoylglutamase HCH_04170 61 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 83647849 Common fliM flagellar motor switch protein FliM HCH_05181 111 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 83649650 Common - hypothetical protein HCH_07045 4 None None None 83644374 Nonpathogen - hypothetical protein HCH_01526 1 None None None 83645810 Common - AraC-type DNA-binding domain-containing protein HCH_03054 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83647554 Common - Lactoylglutathione lyase HCH_04873 19 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 83649167 Nonpathogen - hypothetical protein HCH_06538 1 None None None 83646275 Common - Gluconate kinase HCH_03543 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 83645307 Nonpathogen - hypothetical protein HCH_02515 1 None None None 83644255 Nonpathogen - hypothetical protein HCH_01402 1 None None None 83646659 Common - Electron transfer flavoprotein, alpha subunit HCH_03949 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 83643484 Common - ABC-type multidrug transport system, ATPase and permease components HCH_00591 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83647722 Common - hypothetical protein HCH_05049 4 None None None 83645801 Common pntA NAD(P) transhydrogenase subunit alpha HCH_03045 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 83645803 Common - glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein HCH_03047 5 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 83646468 Common - hypothetical protein HCH_03744 2 None None None 83645450 Common - uncharacterized membrane protein HCH_02672 108 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 83647464 Common - MoxR-like ATPase HCH_04780 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 83648319 Nonpathogen - hypothetical protein HCH_05674 1 None None None 83643548 Common - ABC-type antimicrobial peptide transport system, ATPase component HCH_00657 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83647074 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04379 26 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648209 Common - Oligoketide cyclase/lipid transport protein HCH_05559 7 None None None 83643105 Common - hypothetical protein HCH_00198 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 83643073 Common - uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats HCH_00164 12 COG4700 COG4700, Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats Function unknown 83648055 Common - Rhodanese-related sulfurtransferase HCH_05396 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83644881 Common - hypothetical protein HCH_02060 8 None None None 83643822 Nonpathogen - hypothetical protein HCH_00944 1 None None None 83644466 Common - FOG: EAL domain HCH_01619 166 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83643143 Nonpathogen - hypothetical protein HCH_00238 3 None None None 83648608 Common aroB 3-dehydroquinate synthase HCH_05967 210 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 83648741 Common ksgA dimethyladenosine transferase HCH_06103 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 83643040 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ HCH_00130 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 83644107 Nonpathogen - hypothetical protein HCH_01246 1 None None None 83648841 Common rplX 50S ribosomal protein L24 HCH_06206 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 83647051 Common - predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family HCH_04355 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 83647301 Common - Type II secretory pathway, component PulD HCH_04610 141 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 83647505 Common - hypothetical protein HCH_04821 18 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 83646165 Common - uncharacterized protein involved in exopolysaccharide biosynthesis HCH_03427 84 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 83645148 Common rsuA 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases HCH_02335 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 83644911 Nonpathogen - hypothetical protein HCH_02091 1 None None None 83649466 Common ilvB2 acetolactate synthase 2 catalytic subunit HCH_06858 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83646344 Nonpathogen - hypothetical protein HCH_03614 1 None None None 83643375 Common - FOG: PAS/PAC domain HCH_00476 162 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83648795 Common - Serine acetyltransferase HCH_06159 193 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83643351 Common - Serine phosphatase RsbU, regulator of sigma subunit HCH_00451 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83647330 Common - Adenylate cyclase, family 3 HCH_04641 79 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 83648601 Common - putative ABC transporter ATP-binding protein HCH_05960 244 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83645828 Common - hypothetical protein HCH_03072 17 None None None 83644411 Common - hypothetical protein HCH_01564 19 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 83645099 Common mcrC McrBC 5-methylcytosine restriction system component HCH_02283 19 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 83644403 Common - SAM-dependent methyltransferase HCH_01556 11 None None None 83645528 Nonpathogen - hypothetical protein HCH_02753 9 None None None 83646446 Common - Mg/Co/Ni transporter MgtE (contains CBS domain) HCH_03720 156 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 83644510 Common sfp Phosphopantetheinyl transferase HCH_01667 31 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 83648358 Common - Superfamily I DNA and RNA helicase HCH_05712 25 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 83649071 Common - Cytochrome c5 HCH_06436 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 83644732 Common - hypothetical protein HCH_01907 20 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 83646187 Common - Non-ribosomal peptide synthetase modules and related protein HCH_03450 194 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83649093 Nonpathogen - hypothetical protein HCH_06459 1 None None None 83648748 Common - DnaJ-domain-containing protein 1 HCH_06111 45 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 83645967 Nonpathogen - hypothetical protein HCH_03216 1 None None None 83645939 Nonpathogen - hypothetical protein HCH_03186 1 None None None 83642981 Common - predicted glutathione S-transferase HCH_00070 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83645497 Nonpathogen - hypothetical protein HCH_02722 1 None None None 83648789 Common - Type II secretory pathway, component PulD HCH_06153 139 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 83648535 Common gmhA phosphoheptose isomerase HCH_05896 123 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 83645998 Nonpathogen - hypothetical protein HCH_03248 1 None None None 83643246 Common - predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain HCH_00344 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83645223 Common - Poly(3-hydroxyalkanoate) synthetase HCH_02425 74 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 83645561 Common - putative aminotransferase HCH_02792 4 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83648537 Common - Glutathione S-transferase HCH_05897 90 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83649248 Common - Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases HCH_06624 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 83648944 Nonpathogen - hypothetical protein HCH_06307 1 None None None 83643976 Common - Transcriptional regulator HCH_01108 84 COG1309 AcrR, Transcriptional regulator Transcription 83644680 Common - NAD-dependent aldehyde dehydrogenase HCH_01852 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83642925 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_00012 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83646768 Nonpathogen - hypothetical protein HCH_04066 1 None None None 83643965 Common alc allantoicase HCH_01095 15 COG4266 Alc, Allantoicase Nucleotide transport and metabolism 83646126 Common - ABC-type multidrug transport system, ATPase component HCH_03386 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83648088 Common - Permease of the major facilitator superfamily HCH_05432 228 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83648154 Nonpathogen - hypothetical protein HCH_05502 1 None None None 83648699 Common - hypothetical protein HCH_06058 9 None None None 83647265 Common - predicted transcriptional regulator HCH_04572 95 COG0789 SoxR, Predicted transcriptional regulators Transcription 83648972 Common - hypothetical protein HCH_06336 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 83646994 Common - hypothetical protein HCH_04297 21 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 83647537 Nonpathogen - hypothetical protein HCH_04854 1 None None None 83648986 Common - DNA polymerase I HCH_06350 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 83647860 Common fliG flagellar motor switch protein G HCH_05192 124 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 83646885 Nonpathogen - hypothetical protein HCH_04188 6 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 83648613 Common pilN Tfp pilus assembly protein PilN HCH_05971 46 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 83644740 Common - hypothetical protein HCH_01915 8 COG3313 COG3313, Predicted Fe-S protein General function prediction only 83645940 Nonpathogen - hypothetical protein HCH_03187 1 None None None 83644309 Common - Transposase and inactivated derivatives HCH_01460 33 None None None 83647158 Common - rRNA methylase HCH_04464 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 83646953 Common - Transcriptional regulator HCH_04256 165 COG0583 LysR, Transcriptional regulator Transcription 83646836 Nonpathogen - hypothetical protein HCH_04136 1 None None None 83649368 Nonpathogen - hypothetical protein HCH_06753 1 None None None 83648964 Common - hypothetical protein HCH_06328 11 None None None 83647152 Common - Tfp pilus assembly protein PilF HCH_04458 32 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83644768 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_01945 141 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83647532 Common - Diadenosine tetraphosphatase and related serine/threonine protein phosphatase HCH_04849 47 None None None 83647912 Common - CDP-diglyceride synthetase HCH_05247 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 83649419 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_06805 25 COG0456 RimI, Acetyltransferases General function prediction only 83646933 Common - FOG: CheY-like receiver HCH_04236 76 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83648507 Common ribA GTP cyclohydrolase II HCH_05867 201 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 83643829 Nonpathogen - hypothetical protein HCH_00951 1 None None None 83645111 Common - Transcriptional regulator HCH_02298 178 COG0583 LysR, Transcriptional regulator Transcription 83647161 Common secD preprotein translocase subunit SecD HCH_04467 219 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 83643416 Common - hypothetical protein HCH_00520 34 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 83649334 Nonpathogen - hypothetical protein HCH_06717 1 None None None 83644615 Common recJ single-stranded-DNA-specific exonuclease RecJ HCH_01781 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 83646521 Nonpathogen - endonuclease/exonuclease/phosphatase family protein HCH_03798 1 None None None 83646978 Common - hypothetical protein HCH_04281 2 None None None 83646256 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03521 21 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83643686 Common mnhE putative monovalent cation/H+ antiporter subunit E HCH_00801 79 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 83644521 Common - Lactoylglutathione lyase HCH_01678 39 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 83644015 Nonpathogen - probable acetyltransferase HCH_01148 2 COG3393 COG3393, Predicted acetyltransferase General function prediction only 83644556 Common hemN1 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase HCH_01718 29 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 83646502 Common - Transposase and inactivated derivatives HCH_03780 33 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83646239 Common - FOG: GGDEF domain HCH_03503 144 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83644856 Common - hypothetical protein HCH_02032 37 COG0439 AccC, Biotin carboxylase Lipid metabolism 83645476 Common - DNA internalization-related competence protein ComEC/Rec2 HCH_02699 169 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 83646045 Common - Metal-dependent Hydrolase of the beta-lactamase superfamily III HCH_03300 40 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 83649353 Common - predicted metal-binding protein HCH_06738 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 83643797 Common atpA1 F0F1 ATP synthase subunit alpha HCH_00917 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 83644888 Nonpathogen - hypothetical protein HCH_02067 1 None None None 83646237 Common - Glutamate decarboxylase and related PLP-dependent protein HCH_03501 63 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 83646470 Common - hypothetical protein HCH_03746 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 83643020 Common - NAD-dependent protein deacetylases, SIR2 family HCH_00109 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 83645300 Nonpathogen - hypothetical protein HCH_02508 1 None None None 83645193 Nonpathogen - hypothetical protein HCH_02388 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83649272 Common - hypothetical protein HCH_06649 9 None None None 83648597 Common ribE2 riboflavin synthase subunit alpha HCH_05956 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 83645391 Common - Acetyltransferase HCH_02609 98 COG0456 RimI, Acetyltransferases General function prediction only 83649194 Common - Non-ribosomal peptide synthetase modules and related protein HCH_06566 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83648790 Nonpathogen - hypothetical protein HCH_06154 2 None None None 83648070 Common - uncharacterized protein involved in tellurite resistance HCH_05411 26 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 83646143 Common - probable galactose oxidase containing Kelch motif repeats HCH_03403 13 None None None 83648814 Nonpathogen - hypothetical protein HCH_06179 1 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83648991 Common - predicted integral membrane protein HCH_06356 127 COG0762 COG0762, Predicted integral membrane protein Function unknown 83648856 Common rpsG 30S ribosomal protein S7 HCH_06221 235 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 83648993 Common - predicted GTPase (dynamin-related) HCH_06358 26 COG1160 COG1160, Predicted GTPases General function prediction only 83648732 Nonpathogen - hypothetical protein HCH_06094 1 None None None 83643936 Common - hypothetical protein HCH_01065 50 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 83643340 Common malE maltose ABC transporter periplasmic protein HCH_00440 100 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 83647870 Common - putative oxaloacetate decarboxylase gamma chain HCH_05203 10 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 83643478 Common greB transcription elongation factor GreB HCH_00585 195 COG0782 GreA, Transcription elongation factor Transcription 83644586 Common - Methyl-accepting chemotaxis protein HCH_01751 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83648140 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_05487 10 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644072 Common - protein containing bacterial pre-peptidase C-terminal domain HCH_01209 11 None None None 83643835 Common - Phosphatidylserine/phosphatidylglycerophosphate/c ardiolipin synthases and related enzyme HCH_00957 59 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 83646057 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_03312 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644199 Common hisB Imidazoleglycerol-phosphate dehydratase HCH_01342 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 83647189 Common - ABC-type Fe3+ transport system, periplasmic component HCH_04497 112 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83642995 Common - Methyl-accepting chemotaxis protein HCH_00084 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647180 Common - Adenylate cyclase, family 3 HCH_04487 89 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 83645709 Common - Fe2+/Zn2+ uptake regulation protein HCH_02947 92 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83643053 Common - ABC-type multidrug transport system, ATPase and permease components HCH_00144 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83648521 Common murC UDP-N-acetylmuramate--L-alanine ligase HCH_05882 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 83644687 Common - Thiol-disulfide isomerase and thioredoxins HCH_01860 118 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83645083 Common - hypothetical protein HCH_02267 51 COG2836 COG2836, Uncharacterized conserved protein Function unknown 83648325 Common - hypothetical protein HCH_05680 5 None None None 83645180 Common - hypothetical protein HCH_02372 34 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 83644190 Common - Transposase and inactivated derivatives HCH_01333 33 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 83644721 Nonpathogen - hypothetical protein HCH_01896 1 None None None 83643349 Common - Methyl-accepting chemotaxis protein HCH_00449 25 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83645593 Common - Phospholipid-binding protein HCH_02825 119 COG1881 COG1881, Phospholipid-binding protein General function prediction only 83644260 Nonpathogen - hypothetical protein HCH_01407 1 None None None 83644176 Nonpathogen - hypothetical protein HCH_01318 1 None None None 83645702 Common - ABC-type Mn/Zn transport system, ATPase component HCH_02940 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 83645082 Common hemN2 coproporphyrinogen III oxidase HCH_02266 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 83649024 Common - Site-specific recombinase HCH_06389 52 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 83644519 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs HCH_01676 190 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83646873 Common - Zn-dependent Hydrolase, including glyoxylases HCH_04176 200 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83649215 Common - Membrane-fusion protein HCH_06589 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83642944 Common - uncharacterized protein containing LysM domain HCH_00031 45 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 83646663 Nonpathogen - hypothetical protein HCH_03953 1 None None None 83647877 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase HCH_05211 72 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 83649473 Nonpathogen - hypothetical protein HCH_06865 2 None None None 83646540 Common - Non-ribosomal peptide synthetase modules and related protein HCH_03818 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83642988 Common - FOG: EAL domain HCH_00077 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83644987 Common - hypothetical protein HCH_02168 3 None None None 83643052 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00143 62 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83648386 Nonpathogen - hypothetical protein HCH_05744 1 None None None 83646399 Common - Endoglucanase C-terminal domain/subunit and related protein HCH_03669 15 COG4305 COG4305, Endoglucanase C-terminal domain/subunit and related proteins Carbohydrate transport and metabolism 83646103 Nonpathogen - hypothetical protein HCH_03359 1 None None None 83646083 Common - Transcriptional regulator HCH_03339 59 COG1309 AcrR, Transcriptional regulator Transcription 83647826 Nonpathogen - hypothetical protein HCH_05157 2 COG5373 COG5373, Predicted membrane protein Function unknown 83648077 Nonpathogen - hypothetical protein HCH_05421 1 None None None 83644843 Nonpathogen - hypothetical protein HCH_02019 1 None None None 83644908 Common - Rhs family protein HCH_02088 71 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 83646968 Common - hypothetical protein HCH_04271 31 COG4339 COG4339, Uncharacterized protein conserved in bacteria Function unknown 83644302 Common - hypothetical protein HCH_01452 4 None None None 83645556 Common - Serine/threonine protein phosphatase HCH_02786 85 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83648178 Nonpathogen - hypothetical protein HCH_05526 1 None None None 83648876 Common - Membrane protein related to metalloendopeptidase HCH_06239 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83646436 Common - Chemotaxis protein histidine kinase and related kinase HCH_03709 164 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83649446 Nonpathogen - hypothetical protein HCH_06835 1 None None None 83644912 Nonpathogen - hypothetical protein HCH_02092 2 None None None 83642999 Nonpathogen - hypothetical protein HCH_00088 1 None None None 83643029 Common - predicted membrane protein HCH_00118 34 COG5373 COG5373, Predicted membrane protein Function unknown 83649152 Common - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain HCH_06522 109 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83644140 Common - predicted nucleoside-diphosphate-sugar epimerase HCH_01282 122 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83644747 Common - SecY interacting protein Syd HCH_01923 19 None None None 83643427 Common - AraC-type DNA-binding domain-containing protein HCH_00532 97 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83648151 Common - ATPase with chaperone activity, ATP-binding subunit HCH_05499 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83643596 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_00708 25 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644454 Common - ABC-type uncharacterized transport system, permease component HCH_01607 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 83648933 Common - hypothetical protein HCH_06296 4 None None None 83648146 Nonpathogen - hypothetical protein HCH_05493 1 None None None 83647522 Common - Nucleoside-diphosphate-sugar epimerase HCH_04838 235 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83648107 Common - Ubiquinone biosynthesis protein COQ7 HCH_05452 29 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 83648584 Common - Geranylgeranyl pyrophosphate synthase HCH_05943 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 83645189 Common asnB2 asparagine synthase (glutamine-hydrolyzing) HCH_02383 173 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83647012 Common - probable transcriptional regulator, Cro-like HCH_04315 6 None None None 83646632 Nonpathogen - hypothetical protein HCH_03921 2 None None None 83643637 Common - Chromosome segregation ATPase HCH_00750 9 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 83646364 Nonpathogen - hypothetical protein HCH_03634 1 None None None 83643609 Nonpathogen - hypothetical protein HCH_00721 1 None None None 83644201 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HCH_01346 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 83644418 Common - Lactoylglutathione lyase HCH_01571 11 None None None 83645711 Nonpathogen - hypothetical protein HCH_02949 3 None None None 83647585 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase HCH_04904 209 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 83648499 Common - predicted Permease HCH_05859 128 COG0730 COG0730, Predicted permeases General function prediction only 83649551 Common - Transcriptional regulator HCH_06944 120 COG0583 LysR, Transcriptional regulator Transcription 83646216 Nonpathogen - hypothetical protein HCH_03480 2 None None None 83646450 Common - short chain dehydrogenase HCH_03725 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83649143 Common - NADPH:quinone reductase and related Zn-dependent oxidoreductase HCH_06512 159 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83645774 Nonpathogen - hypothetical protein HCH_03017 1 None None None 83645867 Nonpathogen - hypothetical protein HCH_03112 1 None None None 83649289 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_06668 29 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83643107 Common - hypothetical protein HCH_00200 2 None None None 83648072 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components HCH_05413 69 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83649226 Common - hypothetical protein HCH_06601 22 COG5463 COG5463, Predicted integral membrane protein Function unknown 83645621 Nonpathogen - hypothetical protein HCH_02854 1 None None None 83645219 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase HCH_02420 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 83646062 Common - hypothetical protein HCH_03317 20 COG3831 COG3831, Uncharacterized conserved protein Function unknown 83644037 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_01171 35 None None None 83648231 Nonpathogen - hypothetical protein HCH_05581 1 None None None 83648921 Common - predicted Zn peptidase HCH_06283 55 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 83647227 Nonpathogen - hypothetical protein HCH_04537 1 None None None 83643467 Common - Cell division protein HCH_00574 92 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 83645782 Common - ADP-ribose pyrophosphatase HCH_03026 109 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83648021 Common - Endonuclease I HCH_05359 16 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 83647098 Common - Zn-dependent Hydrolase, including glyoxylases HCH_04403 44 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83648528 Common ftsI penicillin-binding protein 2 HCH_05889 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 83648278 Common - hypothetical protein HCH_05630 4 None None None 83645623 Nonpathogen - hypothetical protein HCH_02858 1 None None None 83643868 Common - hypothetical protein HCH_00993 7 None None None 83643792 Common - Phosphoribosylpyrophosphate synthetase HCH_00912 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 83648293 Nonpathogen - hypothetical protein HCH_05646 1 None None None 83647966 Common - Trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain HCH_05303 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83649265 Common - predicted PP-loop superfamily ATPase HCH_06642 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 83647089 Nonpathogen - hypothetical protein HCH_04394 1 None None None 83647689 Common - predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily) HCH_05014 14 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83647915 Common pyrH uridylate kinase HCH_05251 230 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 83649026 Common - hypothetical protein HCH_06391 6 None None None 83646598 Common - Acetyltransferase (isoleucine patch superfamily) HCH_03881 167 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 83646492 Common - hypothetical protein HCH_03770 4 None None None 83643215 Common - putative heme iron utilization protein HCH_00313 9 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 83646708 Common - Serine/threonine protein kinase HCH_04002 153 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83643260 Common - predicted endonuclease containing a URI domain HCH_00358 73 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 83646532 Common - hypothetical protein HCH_03811 2 None None None 83644634 Common recO DNA repair protein RecO HCH_01803 54 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 83649471 Common - Serine/threonine protein phosphatase HCH_06863 127 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83644876 Common - Amidases related to nicotinamidase HCH_02055 96 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83643346 Common - NTPase HCH_00446 35 COG1986 COG1986, Uncharacterized conserved protein Function unknown 83644502 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01658 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644267 Nonpathogen - hypothetical protein HCH_01415 1 None None None 83647939 Nonpathogen - hypothetical protein HCH_05275 8 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83645821 Common - Membrane protein related to metalloendopeptidase HCH_03065 18 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83648426 Common - Transcriptional regulator HCH_05785 90 COG1309 AcrR, Transcriptional regulator Transcription 83644434 Nonpathogen - hypothetical protein HCH_01588 1 None None None 83646948 Common - hypothetical protein HCH_04251 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 83648063 Common parC DNA topoisomerase IV subunit A HCH_05404 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 83648887 Common mrcB penicillin-binding protein 1B HCH_06250 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 83645761 Nonpathogen - hypothetical protein HCH_03003 1 None None None 83646828 Common - predicted signal transduction protein containing sensor and EAL domains HCH_04128 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83645150 Common - Cold shock protein HCH_02337 172 COG1278 CspC, Cold shock proteins Transcription 83647141 Nonpathogen - hypothetical protein HCH_04447 1 None None None 83645447 Common - Transglutaminase-like enzyme, putative cysteine protease HCH_02669 86 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83643333 Common edd phosphogluconate dehydratase HCH_00433 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 83645968 Common - Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin HCH_03217 28 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 83647166 Common flgL flagellar hook-associated protein FlgL HCH_04472 98 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83644675 Nonpathogen - hypothetical protein HCH_01847 1 None None None 83644340 Common - Transcriptional regulator HCH_01492 159 COG1522 Lrp, Transcriptional regulators Transcription 83648214 Common - hypothetical protein HCH_05564 23 None None None 83648116 Common - ABC-type Fe3+-siderophore transport system, permease component HCH_05462 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83648165 Nonpathogen - hypothetical protein HCH_05513 1 None None None 83645550 Common - RTX toxins and related Ca2+-binding protein HCH_02780 105 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 83649016 Nonpathogen - hypothetical protein HCH_06381 1 None None None 83647503 Common - uncharacterized flagellar protein FlaG HCH_04819 24 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 83645600 Nonpathogen - hypothetical protein HCH_02832 2 None None None 83647887 Common - Pyruvate-formate lyase-activating enzyme HCH_05222 94 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 83644181 Nonpathogen - hypothetical protein HCH_01324 2 None None None 83649254 Common - hypothetical protein HCH_06630 54 COG2862 COG2862, Predicted membrane protein Function unknown 83646117 Nonpathogen - protein containing calx-beta domain HCH_03377 5 None None None 83643281 Common - uncharacterized phage Mu protein gp47-like protein HCH_00380 13 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 83647119 Nonpathogen - hypothetical protein HCH_04425 2 None None None 83644862 Nonpathogen - hypothetical protein HCH_02038 1 None None None 83646750 Common - hypothetical protein HCH_04045 57 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 83649414 Common - predicted metal-dependent hydrolase HCH_06800 25 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 83643112 Common - ABC-type sugar transport system, ATPase components HCH_00206 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83645242 Common ftsK cell division protein FtsK HCH_02445 200 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 83645924 Nonpathogen - hypothetical protein HCH_03171 1 None None None 83647644 Common rmf Ribosome modulation factor HCH_10018 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 83646989 Nonpathogen - hypothetical protein HCH_04292 2 None None None 83646297 Nonpathogen - hypothetical protein HCH_03564 1 None None None 83645512 Common - Glycosyltransferase HCH_02736 157 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83645716 Nonpathogen - hypothetical protein HCH_02955 1 None None None 83644497 Common glcB malate synthase G HCH_01653 81 COG2225 AceB, Malate synthase Energy production and conversion 83645295 Common - Zn-dependent Hydrolase, including glyoxylases HCH_02503 84 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83645378 Nonpathogen - hypothetical protein HCH_02596 5 None None None 83643150 Nonpathogen - hypothetical protein HCH_00245 1 COG5373 COG5373, Predicted membrane protein Function unknown 83647241 Common - Bacteriophage head-tail adaptor HCH_04551 21 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 83645831 Common deoB phosphopentomutase HCH_03075 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 83649518 Common - ABC-type sugar transport system, periplasmic component HCH_06910 63 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83643145 Common - tRNA 2-selenouridine synthase HCH_00240 65 COG2603 COG2603, Predicted ATPase General function prediction only 83643559 Nonpathogen - hypothetical protein HCH_00669 1 None None None 83644116 Common - hypothetical protein HCH_01257 30 COG2606 EbsC, Uncharacterized conserved protein Function unknown 83646486 Nonpathogen - hypothetical protein HCH_03764 1 None None None 83644226 Common - anaerobic nitric oxide reductase transcription regulator HCH_01373 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83647472 Nonpathogen - hypothetical protein HCH_04788 1 None None None 83643674 Common - Phosphate/sulphate Permease HCH_00788 134 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 83647025 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_04329 29 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83644409 Common - Transcriptional regulator HCH_01562 186 COG0583 LysR, Transcriptional regulator Transcription 83646325 Nonpathogen - protein containing glyoxalase/bleomycin resistance protein/dioxygenase superfamily domain HCH_03594 6 None None None 83648589 Nonpathogen - hypothetical protein HCH_05948 1 None None None 161897895 Common ribE1 riboflavin synthase subunit alpha HCH_02673 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 83646068 Common - Glutathione S-transferase HCH_03323 115 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83647655 Common - hypothetical protein HCH_04975 58 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 83643761 Common - predicted membrane protein HCH_00879 26 COG4392 COG4392, Predicted membrane protein Function unknown 83648005 Common - GTPase - Sulfate adenylate transferase subunit 1 HCH_05344 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 83645438 Nonpathogen - hypothetical protein HCH_02659 1 None None None 83649321 Common - hypothetical protein HCH_06703 14 None None None 83646359 Nonpathogen - hypothetical protein HCH_03629 1 None None None 83646273 Common - TRAP-type mannitol/chloroaromatic compound transport system, small permease component HCH_03541 28 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 83647340 Common - predicted transcriptional regulator HCH_04651 143 COG0640 ArsR, Predicted transcriptional regulators Transcription 83644996 Common - acetolactate synthase HCH_02178 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83647828 Nonpathogen - hypothetical protein HCH_05159 1 None None None 83644371 Nonpathogen - hypothetical protein HCH_01523 1 None None None 83646265 Common - protein containing tetratricopeptide repeat HCH_03531 5 None None None 83649135 Common cobN cobaltochelatase, CobN subunit HCH_06504 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 83645899 Common - Fatty-acid desaturase HCH_03146 49 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 83645961 Nonpathogen - hypothetical protein HCH_03210 1 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83648962 Nonpathogen - hypothetical protein HCH_06326 6 None None None 83649014 Common - hypothetical protein HCH_06379 19 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 83645411 Nonpathogen - hypothetical protein HCH_02632 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83647023 Common - hypothetical protein HCH_04327 11 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 83643799 Common atpE1 ATP synthase F0, C subunit HCH_00919 13 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 83644352 Common - uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein HCH_01504 97 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 83643385 Common - Chromosome segregation ATPase HCH_00487 17 None None None 83649666 Common - Tn7-like transposition protein D HCH_07064 18 None None None 83644788 Nonpathogen - hypothetical protein HCH_01966 2 None None None 83648904 Common folK2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HCH_06267 150 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 83645229 Common asd aspartate-semialdehyde dehydrogenase HCH_02431 198 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 83647559 Nonpathogen - hypothetical protein HCH_04878 1 None None None 83648306 Nonpathogen - hypothetical protein HCH_05659 1 None None None 83648706 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_06067 9 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83647808 Common - predicted ATPase HCH_05138 27 COG3899 COG3899, Predicted ATPase General function prediction only 83643707 Nonpathogen - hypothetical protein HCH_00824 2 None None None 83649041 Common speA arginine decarboxylase HCH_06406 178 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 83643700 Nonpathogen - hypothetical protein HCH_00817 1 None None None 83644819 Nonpathogen - hypothetical protein HCH_01995 1 None None None 83643730 Common - Anaerobic dehydrogenase, typically selenocysteine-containing HCH_00847 176 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 83647306 Common fxsA FxsA cytoplasmic membrane protein HCH_04615 70 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 83643808 Nonpathogen - hypothetical protein HCH_00928 2 None None None 83648176 Common - hypothetical protein HCH_05524 8 None None None 83649593 Common fusA2 translation elongation factor G HCH_06988 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 83649450 Nonpathogen - hypothetical protein HCH_06839 1 None None None 83646394 Nonpathogen - hypothetical protein HCH_03664 1 None None None 83648758 Nonpathogen - hypothetical protein HCH_06120 1 None None None 83646671 Common - Glycosyltransferase HCH_03962 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83648057 Common - Truncated, possibly inactive, lysyl-tRNA synthetase (class II) HCH_05398 212 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 83643497 Nonpathogen - hypothetical protein HCH_00604 1 None None None 83647422 Common alkB alkane hydroxylase HCH_04734 26 None None None 83643849 Common - hypothetical protein HCH_00972 29 COG4452 CreD, Inner membrane protein involved in colicin E2 resistance Defense mechanisms 83644598 Common argD acetylornithine aminotransferase HCH_01763 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83647598 Common - Biopolymer transport protein HCH_04917 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83647664 Common - FOG: CBS domain HCH_04984 132 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 83643657 Common - Signal transduction histidine kinase HCH_00770 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83648853 Common rpsJ ribosomal protein S10 HCH_06218 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 83645373 Common - hypothetical protein HCH_02591 5 None None None 83643203 Nonpathogen - hypothetical protein HCH_00301 1 None None None 83643924 Common - Glycosyltransferase involved in cell wall biogenesis HCH_01052 188 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83649421 Nonpathogen - hypothetical protein HCH_06806 1 None None None 83649206 Common - hypothetical protein HCH_06579 26 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 83643199 Common lysA diaminopimelate decarboxylase HCH_00297 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 83649457 Common - hypothetical protein HCH_06847 2 None None None 83648615 Common - Membrane carboxypeptidase/penicillin-binding protein HCH_05973 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 83649200 Common - ABC-type enterobactin transport system, permease component HCH_06573 186 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 83648138 Nonpathogen - hypothetical protein HCH_05485 1 None None None 83646696 Common moaA molybdenum cofactor biosynthesis protein A HCH_03988 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83649403 Nonpathogen - hypothetical protein HCH_06789 1 None None None 83647924 Common dapE succinyl-diaminopimelate desuccinylase HCH_05260 208 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 83645009 Common purL phosphoribosylformylglycinamidine synthase HCH_02192 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 83645118 Common - Transcriptional regulator HCH_02305 109 COG1846 MarR, Transcriptional regulators Transcription 83646033 Common - Transposase and inactivated derivatives HCH_03287 75 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83646857 Common - hypothetical protein HCH_04158 3 None None None 83646054 Nonpathogen - hypothetical protein HCH_03309 1 None None None 83644290 Common - predicted acyltransferase HCH_01439 57 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83644980 Nonpathogen - hypothetical protein HCH_02161 1 None None None 83646797 Common - Transposase and inactivated derivatives HCH_04096 18 None None None 83644922 Common - Transposase and inactivated derivatives HCH_02103 45 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 83643222 Nonpathogen - hypothetical protein HCH_00320 1 None None None 83647932 Nonpathogen - hypothetical protein HCH_05267 1 None None None 83647567 Nonpathogen - hypothetical protein HCH_04886 1 None None None 83648166 Nonpathogen - hypothetical protein HCH_05514 1 None None None 83646281 Nonpathogen - hypothetical protein HCH_03549 1 None None None 83646157 Common - Glycosyltransferase HCH_03419 130 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83647355 Nonpathogen - hypothetical protein HCH_04666 5 None None None 83643119 Nonpathogen - hypothetical protein HCH_00213 4 None None None 83643758 Nonpathogen - hypothetical protein HCH_00876 1 None None None 83648197 Common - ABC-type Fe3+ transport system, periplasmic component HCH_05547 81 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83647994 Common mreD Cell shape-determining protein HCH_05332 44 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 83646141 Nonpathogen - hypothetical protein HCH_03401 1 None None None 83647014 Common - PPE-repeat protein HCH_04317 21 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 83649643 Common - Superfamily I DNA and RNA helicase and helicase subunit HCH_07038 85 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 83645101 Nonpathogen - hypothetical protein HCH_02288 1 None None None 83647146 Common engA GTP-binding protein EngA HCH_04452 238 COG1160 COG1160, Predicted GTPases General function prediction only 83648919 Common - predicted transcriptional regulator HCH_06281 37 COG1396 HipB, Predicted transcriptional regulators Transcription 83645492 Common - uncharacterized protein involved in exopolysaccharide biosynthesis HCH_02716 87 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 83644533 Common - Subtilisin-like serine protease HCH_01695 110 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 83645040 Common - Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family HCH_02223 68 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 83648710 Common - hypothetical protein HCH_06071 12 None None None 83649231 Common - TRAP-type C4-dicarboxylate transport system, large permease component HCH_06607 133 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 83644078 Common smpB SsrA-binding protein HCH_01215 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 83644781 Common - predicted Hydrolase of HD superfamily HCH_01958 45 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 83644393 Nonpathogen - hypothetical protein HCH_01546 1 None None None 83646047 Common - Transcriptional regulator HCH_03302 127 COG1609 PurR, Transcriptional regulators Transcription 83649683 Common - ParA family protein HCH_07081 221 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83647404 Nonpathogen - predicted protein-tyrosine phosphatase HCH_04716 2 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 83644283 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_01432 133 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83647114 Common - Transcriptional regulator HCH_04420 49 COG1522 Lrp, Transcriptional regulators Transcription 83647542 Common - Permease of the major facilitator superfamily HCH_04860 84 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83648089 Common - Multidrug resistance efflux pump HCH_05433 140 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83649343 Common - group II intron-encoding maturase HCH_06727 91 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 83644941 Common - hypothetical protein HCH_02122 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 83644333 Nonpathogen - hypothetical protein HCH_01485 1 None None None 83646318 Common - Nitroreductase HCH_03586 131 COG0778 NfnB, Nitroreductase Energy production and conversion 83647216 Common ureG urease accessory protein UreG HCH_04526 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 83646896 Nonpathogen - hypothetical protein HCH_04199 9 None None None 83646623 Common - hypothetical protein HCH_03911 13 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 83649608 Nonpathogen - hypothetical protein HCH_07003 1 None None None 83645311 Common - ABC-type uncharacterized transport system, duplicated ATPase component HCH_02519 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 83647725 Common - putative exonuclease HCH_05052 94 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 83643397 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00500 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83644344 Common - Membrane protease subunit stomatin/prohibitin-like protein HCH_01496 220 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83643774 Common - hypothetical protein HCH_00892 14 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 83644071 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain HCH_01208 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83645771 Nonpathogen - hypothetical protein HCH_03013 1 None None None 83648079 Common - Dihydrofolate reductase HCH_05422 71 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 83647397 Nonpathogen - hypothetical protein HCH_04709 1 None None None 83645735 Nonpathogen - hypothetical protein HCH_02976 1 None None None 83647892 Nonpathogen - hypothetical protein HCH_05227 2 None None None 83646459 Nonpathogen - hypothetical protein HCH_03735 1 None None None 83642936 Common - Lauroyl/myristoyl acyltransferase HCH_00023 126 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 83644161 Common - Transcriptional regulator HCH_01303 179 COG0583 LysR, Transcriptional regulator Transcription 83645339 Common - hypothetical protein HCH_02548 43 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 83648275 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_05627 45 COG0456 RimI, Acetyltransferases General function prediction only 83647703 Common - sigma 54-dependent transcriptional activator HCH_05030 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 83646782 Common fliE1 flagellar hook-basal body complex protein (FliE) HCH_04079 51 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 83646644 Common gspH general secretion pathway protein H HCH_03933 3 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 83642965 Common - uncharacterized protein required for cytochrome oxidase assembly HCH_00053 49 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 83646260 Common - Histone acetyltransferase HPA2/related acetyltransferase HCH_03525 11 COG0456 RimI, Acetyltransferases General function prediction only 83645207 Common rfbB dTDP-glucose 4,6-dehydratase HCH_02406 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 83647611 Common - FOG: CheY-like receiver HCH_04932 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83649577 Common - hypothetical protein HCH_06972 3 None None None 83645602 Nonpathogen - hypothetical protein HCH_10011 2 None None None 83643438 Common - Methyl-accepting chemotaxis protein HCH_00543 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83647418 Common zipA cell division protein ZipA HCH_04730 45 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 83649196 Common - Cytosine deaminase and related metal-dependent Hydrolase HCH_06568 145 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83649632 Nonpathogen - hypothetical protein HCH_07026 1 None None None 83648659 Nonpathogen - hypothetical protein HCH_06019 2 None None None 83643586 Nonpathogen - hypothetical protein HCH_00697 3 None None None 83644275 Common - hypothetical protein HCH_01423 14 None None None 83649572 Common - ABC-type sugar transport system, ATPase components HCH_06967 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83649506 Common - hypothetical protein HCH_06899 17 COG3738 COG3738, Uncharacterized protein conserved in bacteria Function unknown 83645019 Common - Nucleotidyltransferase/DNA polymerase involved in DNA repair HCH_02201 62 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 83646922 Nonpathogen - hypothetical protein HCH_04225 4 None None None 83644809 Common - hypothetical protein HCH_01986 7 COG0393 COG0393, Uncharacterized conserved protein Function unknown 83649274 Common - hypothetical protein HCH_06651 2 None None None 83643269 Common - Response regulator containing a CheY-like receiver domain and a GGDEF domain HCH_00368 189 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83648362 Nonpathogen - hypothetical protein HCH_05718 1 None None None 83646248 Nonpathogen - hypothetical protein HCH_03512 1 None None None 83647444 Nonpathogen - hypothetical protein HCH_04759 1 None None None 83648910 Common - DNA primase (bacterial type) HCH_06273 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 83644773 Common aruD succinylglutamate 5-semialdehyde dehydrogenase HCH_01950 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83645124 Common - ABC-type uncharacterized transport system, permease component HCH_02311 113 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 83645159 Common - predicted amidohydrolase HCH_02346 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 83645672 Nonpathogen - hypothetical protein HCH_02908 1 None None None 83648685 Common - Microcystin-dependent protein HCH_06045 34 COG4675 MdpB, Microcystin-dependent protein Function unknown 83645665 Nonpathogen - hypothetical protein HCH_02901 1 None None None 83649652 Common - hypothetical protein HCH_07048 5 None None None 83646305 Common - Outer membrane receptor protein, mostly Fe transport HCH_03573 90 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83645128 Common ushA bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor HCH_02315 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 83647952 Common - NhaP-type Na+/H+ and K+/H+ antiporters HCH_05288 118 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 83643627 Nonpathogen - hypothetical protein HCH_00739 1 None None None 83643252 Nonpathogen - hypothetical protein HCH_00350 1 None None None 83649086 Nonpathogen - hypothetical protein HCH_06452 1 None None None 83643931 Common - Inorganic pyrophosphatase HCH_01060 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 83648624 Common - Signal transduction protein containing GAF and PtsI domains HCH_05983 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 83649689 Common - putative inner membrane protein translocase component YidC HCH_07087 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 83647294 Common purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase HCH_04603 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 83644297 Common - predicted esterase HCH_01447 94 COG0627 COG0627, Predicted esterase General function prediction only 83643352 Common - uncharacterized flavoprotein HCH_00452 35 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 83644662 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease components HCH_01833 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83649077 Nonpathogen - hypothetical protein HCH_06443 1 None None None 83649308 Common - Spermidine/putrescine-binding periplasmic protein HCH_06688 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83644507 Nonpathogen - hypothetical protein HCH_01664 1 None None None 83647490 Common - predicted membrane protein HCH_04806 17 COG2259 COG2259, Predicted membrane protein Function unknown 83645385 Common - FOG: TPR repeat HCH_02603 50 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83648435 Common - hypothetical protein HCH_05794 15 None None None 83645904 Nonpathogen - hypothetical protein HCH_03151 1 None None None 83648122 Nonpathogen - hypothetical protein HCH_05468 1 None None None 83642931 Common - Na+/phosphate symporter HCH_00018 79 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 83645330 Nonpathogen - hypothetical protein HCH_02539 1 None None None 83649366 Common - hypothetical protein HCH_06751 2 None None None 83645984 Common - Transcriptional regulator HCH_03234 93 COG1309 AcrR, Transcriptional regulator Transcription 83647608 Common - sigma 54-dependent transcriptional activator containing CheY-like receiver domain HCH_04929 188 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83643547 Common - ABC-type metal ion transport system, periplasmic component/surface adhesin HCH_00656 22 None None None 83646591 Common - SAM-dependent methyltransferase HCH_03874 35 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 83649307 Common - predicted endonuclease containing a URI domain HCH_06687 64 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 83646771 Nonpathogen - hypothetical protein HCH_04068 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 83643183 Common - hypothetical protein HCH_00280 13 COG5589 COG5589, Uncharacterized conserved protein Function unknown 83643573 Nonpathogen - hypothetical protein HCH_00683 1 None None None 83648244 Common - hypothetical protein HCH_05595 81 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 83645047 Common - ABC-type polysaccharide/polyol phosphate export systems, permease component HCH_10008 135 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 83646422 Common - Diaminopimelate decarboxylase HCH_03695 183 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 83643329 Common - Cation transport ATPase HCH_00429 230 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 83643665 Common - Outer membrane protein and related peptidoglycan-associated (lipo)protein HCH_00779 161 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83644607 Common rimM 16S rRNA processing protein RimM HCH_01773 145 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 83649613 Nonpathogen - hypothetical protein HCH_07008 1 None None None 83647366 Common wcaJ putative colanic acid biosynthsis UDP-glucose lipid carrier transferase HCH_04677 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 83648189 Nonpathogen - hypothetical protein HCH_05538 6 None None None 83643885 Common coaD phosphopantetheine adenylyltransferase HCH_01010 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 83644443 Common - hypothetical protein HCH_01596 51 COG2930 COG2930, Uncharacterized conserved protein Function unknown 83648494 Common ilvD dihydroxy-acid dehydratase HCH_05854 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 83643087 Common - protein containing HTH domain HCH_00179 14 COG3655 COG3655, Predicted transcriptional regulator Transcription 83649628 Common - predicted metal-dependent membrane protease HCH_07023 25 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 83646906 Common - putative threonine efflux protein HCH_04209 112 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83649586 Common - ABC-type sugar transport system, permease components HCH_06981 149 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83644398 Nonpathogen - hypothetical protein HCH_01551 13 None None None 83647248 Nonpathogen - hypothetical protein HCH_04558 1 None None None 83644178 Nonpathogen - hypothetical protein HCH_01320 1 None None None 83645609 Common - TonB-dependent receptor family protein HCH_02841 78 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 83647376 Common - Glycosyltransferase involved in cell wall biogenesis HCH_04688 219 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83648255 Nonpathogen - hypothetical protein HCH_05607 1 None None None 83649690 Common rnpA ribonuclease P protein component HCH_10034 59 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 83645728 Nonpathogen - hypothetical protein HCH_02968 1 None None None 83644869 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase HCH_02048 31 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83646490 Nonpathogen - hypothetical protein HCH_03768 6 None None None 83648268 Common - hypothetical protein HCH_05620 3 None None None 83647998 Common gatC glutamyl-tRNA(Gln) amidotransferase, C subunit HCH_05336 144 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 83644478 Common tdh L-threonine 3-dehydrogenase HCH_01632 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 83644960 Common - predicted metal-binding, possibly nucleic acid-binding protein HCH_02141 52 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 83647755 Common - ABC-type transport system involved in multi-copper enzyme maturation, permease component HCH_05084 46 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 83645233 Common trpB1 tryptophan synthase subunit beta HCH_02436 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 83643844 Common - phosphoglycerate mutase HCH_00966 74 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 83645860 Common - probable polygalacturonase HCH_03104 16 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 83646717 Common narH nitrate reductase, beta subunit HCH_04010 148 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 83649371 Common - putative exonuclease HCH_06756 180 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83645740 Common - Subtilisin-like serine protease HCH_02981 113 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 83649295 Common - hypothetical protein HCH_06675 7 None None None 83643752 Common - Chitinase HCH_00869 39 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 83646003 Nonpathogen - hypothetical protein HCH_03254 1 None None None 83643096 Common - predicted hydrolase of the alpha/beta-hydrolase fold HCH_00189 64 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 83642914 Nonpathogen - hypothetical protein HCH_00001 1 None None None 83643227 Common - Signal transduction histidine kinase regulating C4-dicarboxylate transport system HCH_00325 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83645053 Common - SAM-dependent methyltransferase HCH_02237 88 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83644577 Common - protein containing StAR-related lipid-transfer (START) domain HCH_01741 14 None None None 83645679 Common - hypothetical protein HCH_02915 40 COG1284 COG1284, Uncharacterized conserved protein Function unknown 83648668 Common - Ornithine/acetylornithine aminotransferase HCH_06028 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83647785 Common yscU Type III secretory pathway, component EscU HCH_05114 130 COG4792 EscU, Type III secretory pathway, component EscU Intracellular trafficking and secretion 83647183 Common - ABC-type multidrug transport system, permease component HCH_04490 145 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 83644958 Common maf1 maf protein HCH_02139 194 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 83645485 Common - Transcriptional regulator HCH_02709 137 COG1802 GntR, Transcriptional regulators Transcription 83647901 Common - ATPase with chaperone activity, ATP-binding subunit HCH_05236 6 None None None 83645002 Common prc Periplasmic protease HCH_02184 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 83644321 Common - ABC-type spermidine/putrescine transport system, permease component I HCH_01473 137 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 83645201 Common - Glycosyltransferase HCH_02400 176 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83645321 Common nhaB sodium/proton antiporter HCH_02529 25 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 83645892 Common - uncharacterized protein involved in formation of curli polymers HCH_03138 24 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 83644972 Common ppiB Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family HCH_02152 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 83644552 Common dnaB replicative DNA helicase HCH_01714 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 83648652 Common - Phosphoribosylamine-glycine ligase HCH_06012 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 83643738 Common - hypothetical protein HCH_00855 19 None None None 83644380 Common ahcY S-adenosyl-L-homocysteine hydrolase HCH_01532 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 83645326 Common - NADPH:quinone reductase and related Zn-dependent oxidoreductase HCH_02535 160 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83647253 Common - Restriction endonuclease HCH_10016 48 COG1403 McrA, Restriction endonuclease Defense mechanisms 83647987 Common ptsH phosphocarrier protein HPr HCH_05325 155 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 83646812 Common - probable carbohydrate binding domain HCH_04112 13 None None None 83643235 Common - hypothetical protein HCH_00333 23 None None None 83646664 Nonpathogen - hypothetical protein HCH_03955 1 None None None 83642953 Common - Molecular chaperone (small heat shock protein) HCH_00041 165 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 83649554 Common - hypothetical protein HCH_06947 4 None None None 83643443 Common - Periplasmic protein TonB, links inner and outer membranes HCH_00548 58 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83648714 Common - AraC-type DNA-binding domain-containing protein HCH_06075 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83646685 Nonpathogen - hypothetical protein HCH_03976 1 None None None 83643368 Nonpathogen - hypothetical protein HCH_00468 1 None None None 83644967 Common - predicted periplasmic solute-binding protein HCH_02147 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 83645844 Common - ABC-type Fe3+ transport system, periplasmic component HCH_03088 114 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83647455 Common - uncharacterized protein, possibly involved in aromatic compounds catabolism HCH_04771 41 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 83648415 Common - TRAP-type C4-dicarboxylate transport system, periplasmic component HCH_05774 96 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83647080 Common - Sphingosine kinase and enzyme related to eukaryotic diacylglycerol kinase HCH_04385 75 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 83648833 Common rplO ribosomal protein L15 HCH_06198 199 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 83648377 Common parE DNA topoisomerase IV subunit B HCH_05734 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 83645022 Common - peptidase family M16 (insulinase) protein HCH_02204 157 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 83643166 Common - Periplasmic protease HCH_00263 4 None None None 83643872 Nonpathogen - hypothetical protein HCH_00997 3 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 83648033 Common - Permease of the drug/metabolite transporter (DMT) superfamily HCH_05375 135 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83647055 Common - short-chain alcohol dehydrogenase-like protein HCH_04359 204 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83647629 Nonpathogen - hypothetical protein HCH_04950 7 None None None 83643419 Common - DnaJ-class molecular chaperone HCH_00524 234 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83648674 Nonpathogen - RedY-like protein HCH_06034 2 None None None 83645356 Common - Transposase and inactivated derivatives HCH_02566 33 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83647647 Common - predicted Co/Zn/Cd cation transporters HCH_04967 194 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 83645318 Common - SAM-dependent methyltransferase HCH_02526 80 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83649542 Common - Transcriptional regulator HCH_06935 60 COG2808 PaiB, Transcriptional regulator Transcription 83646427 Common - 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HCH_03700 14 None None None 83649383 Common - probable phage head completeion protein HCH_06769 18 None None None 83645670 Nonpathogen - hypothetical protein HCH_02906 1 None None None 83648285 Nonpathogen - hypothetical protein HCH_05637 1 None None None 83649186 Nonpathogen - hypothetical protein HCH_06558 1 None None None 83643410 Nonpathogen - hypothetical protein HCH_00514 1 None None None 83645367 Common - RTX toxins and related Ca2+-binding protein HCH_02583 98 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 83644800 Common - Short-chain alcohol dehydrogenase of unknown specificity HCH_01977 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 83645396 Common rnd ribonuclease D HCH_02616 116 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 83647618 Common galE UDP-glucose 4-epimerase HCH_04939 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 83645254 Common - uncharacterized conserved protein, contains FHA domain HCH_02457 22 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 83643408 Nonpathogen - hypothetical protein HCH_00511 1 None None None